NAD(P) transhydrogenase alpha subunit C-terminal
Glycosyltransferase subfamily 4-like N-terminal
Major facilitator superfamily (MFS) profile
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Phosphatidic acid phosphatase type 2/haloperoxidase
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Reversibly protonated during proton transport
RNA polymerase sigma factor 70 region 4 type 2
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Positions MEP for the nucleophilic attack
Nitrile hydratase alpha /Thiocyanate hydrolase gamma
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Flagellar assembly protein FliH/Type III secretion system HrpE
Aminoacyl-transfer RNA synthetases class-II family profile
Mandelate racemase/muconate lactonizing enzyme C-terminal
Glucose-methanol-choline oxidoreductase C-terminal
Cobalt ABC transporter substrate-binding protein
Putative regulatory protein FmdB Zinc ribbon
NADH:ubiquinone oxidoreductase-like 20kDa subunit
N-end rule aminoacyl transferase C-terminal
Formylmethanofuran dehydrogenase subunit E
NIF system FeS cluster assembly NifU N-terminal
Probable periplasmic serine endoprotease DegP-like
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
Ribonucleotide reductase large subunit C-terminal
Invasion associated locus B family protein
TRAP C4-dicarboxylate transport system permease DctM subunit
Ribonucleotide reductase large subunit N-terminal
Transcription regulator AsnC/Lrp ligand binding
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Electron transfer flavoprotein alpha/beta-subunit N-terminal
TonB-dependent receptor-like beta-barrel
Cytochrome c-type biogenesis protein CcmF C-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Lysozyme inhibitor LprI N-terminal domain-containing protein
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Alanyl-transfer RNA synthetases family profile
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Heme-copper oxidase subunit III family profile
Resolvase/invertase-type recombinase catalytic
S-adenosyl-L-homocysteine hydrolase NAD binding
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Important for substrate specificity; cannot use PPi as phosphoryl donor
Periplasmic nitrate reductase, electron transfer subunit
Organic solvent tolerance-like N-terminal
Organic solvent tolerance-like N-terminal domain-containing protein
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Flagellar motor switch protein FliN-like C-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Tryptophan synthase beta chain-like PALP
Invasion associated locus B (IalB) protein
Prokaryotic-type class I peptide chain release factors
Solute-binding protein family 3/N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
DNA-directed RNA polymerase RpoA/D/Rpb3-type
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Membrane fusion protein biotin-lipoyl like
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Activator of Hsp90 ATPase homologue 1-like C-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Type 2A encapsulin shell protein SrpI-like
Penicillin-binding protein transpeptidase
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Signal transduction histidine kinase subgroup 2 dimerisation and phosphoacceptor
Large ribosomal subunit protein uL2 C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
PQQ-dependent catabolism-associated beta-propeller protein
Polymerase/histidinol phosphatase N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Solute-binding protein family 3/N-terminal domain-containing protein
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr C-terminal
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr N-terminal
Chromosomal replication initiator DnaA C-terminal
General stress protein FMN-binding split barrel
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Polysaccharide biosynthesis protein C-terminal
Quinoprotein dehydrogenase-associated SoxYZ-like carrier
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Translation elongation factor P/YeiP central
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Transglycosylase SLT domain-containing protein
Putative exodeoxyribonuclease 8 PDDEXK-like
Dinitrogenase iron-molybdenum cofactor biosynthesis
Involved in ionization of N3 of dUMP, leading to its activation
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Inner membrane protein YgaP-like transmembrane
Large ribosomal subunit protein uL6 alpha-beta
UDP N-acetylglucosamine O-acyltransferase C-terminal
Plasmid replication protein C N-terminal
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
AB hydrolase-1 domain-containing protein
Aconitase A/isopropylmalate dehydratase small subunit swivel
Pseudouridine synthase I TruA alpha/beta
NADH:ubiquinone oxidoreductase 30kDa subunit
NIF system FeS cluster assembly NifU C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
S-adenosylmethionine-dependent methyltransferase
RNA 2-O ribose methyltransferase substrate binding
Ligand-binding protein with streptavidin-like fold
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Outer membrane lipoprotein carrier protein LolA
Carbohydrate binding module xylan-binding
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Small ribosomal subunit protein uS4 N-terminal
Sulfatase-modifying factor enzyme domain-containing protein
Polysaccharide chain length determinant N-terminal
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Survival protein SurE-like phosphatase/nucleotidase
Membrane insertase YidC/Oxa/ALB C-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Mannose-6-phosphate isomerase type II C-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Plays an important role in substrate specificity
DNA topoisomerase I catalytic core eukaryotic-type
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
ABC transporter substrate-binding protein PnrA-like
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
ATP synthase F1 complex delta/epsilon subunit N-terminal
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
O-(3'-phospho-DNA)-tyrosine intermediate
Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase
Outer membrane protein beta-barrel domain-containing protein
Transposase IS116/IS110/IS902 C-terminal
Endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
Poly-beta-hydroxybutyrate polymerase N-terminal
ABC-type glycine betaine transport system substrate-binding
Quercetin 2,3-dioxygenase C-terminal cupin
RNA polymerase sigma factor 70 region 1.1
SUF system FeS cluster assembly SufBD N-terminal
Ankyrin repeat domain-containing protein
Methionyl-tRNA synthetase anticodon-binding
Phosphotransferase system enzyme I N-terminal
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Involved in tetramerization or stability of the tetramer
Terminase large subunit gp17-like C-terminal
Interaction with polymerase core subunit RpoC
Leucine-binding protein domain-containing protein
Surface antigen domain-containing protein
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Metallo-beta-lactamase domain-containing protein
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Glycine zipper domain-containing protein
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Alginate export domain-containing protein
YbaK/aminoacyl-tRNA synthetase-associated
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Glycine cleavage T-protein C-terminal barrel
Glycosyl transferase family 3 N-terminal
Phosphogluconate dehydrogenase NAD-binding putative C-terminal
Saccharopine dehydrogenase-like C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Glycine-zipper-containing OmpA-like membrane
Glycine-zipper-containing OmpA-like membrane domain-containing protein
Glucose-methanol-choline oxidoreductase N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Autotransporter secretion inner membrane protein TamB
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Thiol:disulfide interchange protein DsbD N-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Interacts with tRNA; defines subfamily-specific binding signature
Histidine-specific methyltransferase SAM-dependent
Sugar fermentation stimulation protein C-terminal
Anthranilate synthase component I N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Molybdopterin cofactor biosynthesis C (MoaC)
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Glycosyl transferase family 28 C-terminal
TtsA-like Glycoside hydrolase family 108
Glycogen debranching enzyme bacterial and archaeal type N-terminal
Polysaccharide biosynthesis protein CapD-like
Large ribosomal subunit protein uL15/eL18
Nitrogenase molybdenum-iron protein beta chain N-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
May play a role in metal incorporation in vivo
May play a role in transmitting local conformational changes
Peptidase M1 membrane alanine aminopeptidase
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Cobaltochelatase subunit CobS N-terminal
ABC-type transport auxiliary lipoprotein component
ABC-type transport auxiliary lipoprotein component domain-containing protein
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Release factor glutamine methyltransferase N-terminal
Gamma-butyrobetaine hydroxylase-like N-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Ribose-phosphate pyrophosphokinase N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Proton acceptor; for glutaminase activity
Peptidase S9 prolyl oligopeptidase catalytic
Could play a key role in the communication between the regulatory and the substrate sites
Putative glycogen debranching enzyme N-terminal
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Regulator of nucleoside diphosphate kinase N-terminal
Transcription elongation factor GreA/GreB C-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Required for zinc-mediated homotetramerization and catalytic activity
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
C4-dicarboxylate ABC transporter substrate-binding protein
DNA replication/recombination mediator RecO N-terminal
DNA-directed DNA polymerase family A palm
Aspartate/homoserine dehydrogenase NAD-binding
Antitoxin Xre/MbcA/ParS-like toxin-binding
Pyruvate phosphate dikinase AMP/ATP-binding
Lipocalin-like domain-containing protein
Ionotropic glutamate receptor C-terminal
Exopolysaccharide biosynthesis protein YbjH
Bacterial OB-fold domain-containing protein
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
High-affinity branched-chain amino acid transport system permease LivHM N-terminal
Transcription elongation factor GreA/GreB N-terminal
Urease accessory protein UreH-like transmembrane
Alkaline proteinase inhibitor/ Outer membrane lipoprotein Omp19 domain-containing protein
Rap1a immunity protein domain-containing protein
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
glutathione gamma-glutamylcysteinyltransferase
Heat-inducible transcription repressor HrcA C-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
SGNH hydrolase-type esterase domain-containing protein
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
PrcB C-terminal domain-containing protein
Alpha-(1,3)-fucosyltransferase FucT N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Outer membrane protein assembly factor BamD
Tetrahydrodipicolinate-N-succinyltransferase chain A
CobB/CobQ-like glutamine amidotransferase
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Flagellar hook-length control protein-like C-terminal
Gp5/Type VI secretion system Vgr protein OB-fold
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Flagellar basal body-associated protein FliL
FAD-dependent oxidoreductase 2 FAD binding
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Endoribonuclease L-PSP/chorismate mutase-like