Aminoacyl-transfer RNA synthetases class-II family profile
Putative beta-lactamase-inhibitor-like PepSY-like
6-hydroxymethylpterin diphosphokinase MptE-like
Schiff-base intermediate with acetaldehyde
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Pyruvate/ketoisovalerate oxidoreductase catalytic
LPS export ABC transporter periplasmic protein LptC
NIF system FeS cluster assembly NifU C-terminal
NIF system FeS cluster assembly NifU N-terminal
Polymerase/histidinol phosphatase N-terminal
RNA polymerase sigma factor 70 region 4 type 2
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Phosphomannose isomerase type I catalytic
Tryptophan synthase beta chain-like PALP
Membrane insertase YidC/Oxa/ALB C-terminal
Alpha-glycerophosphate oxidase C-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Solute-binding protein family 3/N-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Glycoside hydrolase family 57 N-terminal
Glucosamine/galactosamine-6-phosphate isomerase
PBS lyase HEAT domain protein repeat-containing protein
Peptidase M10 metallopeptidase domain-containing protein
Gfo/Idh/MocA-like oxidoreductase N-terminal
S-adenosylmethionine-dependent methyltransferase
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Phosphotransferase system enzyme I N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Release factor glutamine methyltransferase N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
N-sulphoglucosamine sulphohydrolase C-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
ATPsynthase alpha/beta subunit N-terminal extension
Lysidine-tRNA(Ile) synthetase C-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Serpentine_recp domain containing protein
ABC transporter substrate-binding protein PnrA-like
Pyruvate phosphate dikinase AMP/ATP-binding
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Polysaccharide biosynthesis protein CapD-like
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Essential for prephenate dehydratase activity
Trigger factor ribosome-binding bacterial
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Cation-transporting P-type ATPase N-terminal
Plays an important role in substrate specificity
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Interaction with polymerase core subunit RpoC
Alanyl-transfer RNA synthetases family profile
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Penicillin-binding protein transpeptidase
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Aconitase A/isopropylmalate dehydratase small subunit swivel
Phosphoribosylformylglycinamidine synthase linker
D-galactose/methyl-galactoside binding periplasmic protein MglB
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
ABC-type uncharacterised transport system
Phosphocysteine intermediate; for EIIB activity
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Ionotropic glutamate receptor C-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Curli production assembly/transport component CsgG
Aspartate/homoserine dehydrogenase NAD-binding
Type VII secretion system protein EssD-like
O-(3'-phospho-DNA)-tyrosine intermediate
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Thymidylate synthase/dCMP hydroxymethylase
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Diacylglycerol glucosyltransferase N-terminal
Glycosyl transferase family 28 C-terminal
Flagellar Assembly Protein A N-terminal region
Signal recognition particle SRP54 helical bundle
Putative beta-lactamase-inhibitor-like PepSY-like domain-containing protein
Important for guanine/8-oxoguanine distinction
Major facilitator superfamily (MFS) profile
Gfo/Idh/MocA-like oxidoreductase C-terminal
Flagellar motor switch protein FliN-like C-terminal
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Bacterial transcription activator effector binding
NADH-ubiquinone oxidoreductase 51kDa subunit FMN-binding
Putative regulatory protein FmdB Zinc ribbon
Type I restriction modification DNA specificity
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Translation elongation factor P/YeiP central
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Restriction system protein Mrr-like N-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Outer membrane protein beta-barrel domain-containing protein
Transcription factor NikR nickel binding C-terminal
Large ribosomal subunit protein uL15/eL18
Large ribosomal subunit protein uL2 C-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Proton acceptor; for glutaminase activity
SMODS-associated and fused to various effectors
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Transcriptional regulator LacI/GalR-like sensor
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
RNA binding; important for wobble base 34 recognition
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Flagellar hook-length control protein-like C-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Alpha-amylase/4-alpha-glucanotransferase C-terminal
Alpha-amylase/4-alpha-glucanotransferase central
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase N-terminal
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Phosphatidylglycerol lysyltransferase C-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Membrane fusion protein biotin-lipoyl like
RND efflux pump membrane fusion protein barrel-sandwich
1,4-alpha-glucan branching enzyme C-terminal
Reversibly protonated during proton transport
N6 adenine-specific DNA methyltransferase N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Fe/B12 periplasmic-binding domain-containing protein
N-acetylmuramoyl-L-alanine amidase domain-containing protein
Plays an important role in discriminating NADH against NADPH
Could be important to modulate the pK values of the two catalytic cysteine residues
Sodium/calcium exchanger membrane region
Molybdopterin cofactor biosynthesis C (MoaC)
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Chromosomal replication initiator DnaA C-terminal
CASTOR/POLLUX/SYM8 ion channel conserved
Pseudouridine synthase I TruA alpha/beta
Phage terminase large subunit N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Auto-transporter adhesin head GIN domain-containing protein
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Ribosomal RNA adenine methylase transferase N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
O-(5'-phospho-DNA)-tyrosine intermediate
UDP N-acetylglucosamine O-acyltransferase C-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
DNA mismatch repair proteins mutS family
Ribose-phosphate pyrophosphokinase N-terminal
Outer membrane lipoprotein carrier protein LolA
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Lipocalin-like domain-containing protein
YbaK/aminoacyl-tRNA synthetase-associated
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
AMP-activated protein kinase glycogen-binding
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Cell envelope-related transcriptional attenuator
Glycosyltransferase subfamily 4-like N-terminal
Flagellar assembly protein FliH/Type III secretion system HrpE
Type III restriction/modification enzyme methylation subunit
NADH:flavin oxidoreductase/NADH oxidase N-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding