Major facilitator superfamily (MFS) profile
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Large ribosomal subunit protein uL6 alpha-beta
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Glycine cleavage T-protein C-terminal barrel
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Arabinogalactan endo-beta-1,4-galactanase
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Siderophore-interacting protein C-terminal
Phosphotransferase system enzyme I N-terminal
Ribosomal RNA small subunit methyltransferase E methyltransferase
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Pyrroline-5-carboxylate reductase catalytic N-terminal
Molybdenum cofactor biosynthesis protein F N-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Glucosamine/galactosamine-6-phosphate isomerase
Glycosyltransferase subfamily 4-like N-terminal
Solute-binding protein family 3/N-terminal
Pseudouridine synthase I TruA alpha/beta
Prepilin type IV endopeptidase peptidase
6-phosphogluconate dehydrogenase C-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Prokaryotic-type class I peptide chain release factors
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Shikimate dehydrogenase substrate binding N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Phenol hydroxylase C-terminal dimerisation
Large ribosomal subunit protein bL12 C-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
ABC-type glycine betaine transport system substrate-binding
Aminoacyl-transfer RNA synthetases class-II family profile
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Formamidopyrimidine-DNA glycosylase catalytic
Ionotropic glutamate receptor C-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Flagellar motor switch protein FliN-like C-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Bacterial bifunctional deaminase-reductase C-terminal
Electron transfer via tryptophanyl radical
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
RNA polymerase sigma factor 70 region 4 type 2
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Beta-hexosaminidase bacterial type N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Could play a key role in the communication between the regulatory and the substrate sites
Alpha-D-phosphohexomutase alpha/beta/alpha
ATP synthase F1 complex delta/epsilon subunit N-terminal
RNA 2-O ribose methyltransferase substrate binding
Essential for prephenate dehydratase activity
Ribose-phosphate pyrophosphokinase N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
N-sulphoglucosamine sulphohydrolase C-terminal
Penicillin-binding protein transpeptidase
Interaction with polymerase core subunit RpoC
Glycoside hydrolase family 42 N-terminal
Alpha-glycerophosphate oxidase C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Cytochrome C biogenesis protein transmembrane
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Tryptophan synthase beta chain-like PALP
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Large ribosomal subunit protein bL12 oligomerization
Cytochrome bc1 complex cytochrome c subunit
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Threonine/serine exporter-like N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Chromosomal replication initiator DnaA C-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Heat-inducible transcription repressor HrcA C-terminal
Glycoside-hydrolase family GH114 TIM-barrel
Glycoside-hydrolase family GH114 TIM-barrel domain-containing protein
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Exonuclease VII large subunit C-terminal
Glycoside hydrolase family 31 N-terminal
Peptide methionine sulphoxide reductase MsrA
Helix-hairpin-helix DNA-binding motif class 1
O-(5'-phospho-DNA)-tyrosine intermediate
SUF system FeS cluster assembly SufBD N-terminal
N-acetylneuraminic acid synthase N-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Carbamoyl-phosphate synthase small subunit N-terminal
Peptidase M1 membrane alanine aminopeptidase
Phosphatidic acid phosphatase type 2/haloperoxidase
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Sporulation transcription regulator WhiA N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Elongation factor G-binding protein C-terminal treble-clef zinc-finger
Putative oxidoreductase/dehydrogenase Rossmann-like
Glucose-6-phosphate isomerase prokaryote
Bacterial type II secretion system protein E
Pyrimidine nucleoside phosphorylase C-terminal
Alpha-L-glutamate ligase-related protein ATP-grasp
Activator of Hsp90 ATPase homologue 1-like C-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
tRNA pseudouridine synthase II TruB subfamily 2 C-terminal
tRNA pseudouridylate synthase B C-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Polymerase/histidinol phosphatase N-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Schiff-base intermediate with D-ribose 5-phosphate
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
NIF system FeS cluster assembly NifU N-terminal
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
DNA replication/recombination mediator RecO N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Na+/H+ antiporter MnhB subunit-related protein
Nitrate ABC transporter substrate-binding protein
Reversibly protonated during proton transport
General stress protein FMN-binding split barrel
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Aspartate/homoserine dehydrogenase NAD-binding
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Small ribosomal subunit protein uS4 N-terminal
DNA topoisomerase I catalytic core eukaryotic-type
BAAT/Acyl-CoA thioester hydrolase C-terminal
ABC transporter substrate-binding protein PnrA-like
Important for substrate specificity; cannot use PPi as phosphoryl donor
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Plays an important role in substrate specificity
Release factor glutamine methyltransferase N-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Moves into active site upon enzyme activation, plays a role in electron transfer
Phosphomannose isomerase type I catalytic
Cell envelope-related transcriptional attenuator
Bacterial transcription activator effector binding
Signal recognition particle SRP54 helical bundle
Polysaccharide chain length determinant N-terminal
ABC transporter substrate-binding protein
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Galactofuranosyltransferase GlfT2 N-terminal
Galactofuranosyltransferase-2 C-terminal
Phosphoribosylformylglycinamidine synthase linker
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Resolvase/invertase-type recombinase catalytic
Putative regulatory protein FmdB Zinc ribbon
DNA-directed DNA polymerase family A palm
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Thymidylate synthase/dCMP hydroxymethylase
Glycoamylase-like domain-containing protein
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Gram-positive cocci surface proteins LPxTG domain-containing protein
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Ribosomal RNA adenine methylase transferase N-terminal
Glycosyl transferase family 3 N-terminal
Mannose-6-phosphate isomerase type II C-terminal
Endoribonuclease L-PSP/chorismate mutase-like
Large ribosomal subunit protein uL2 C-terminal
Translation elongation factor P/YeiP central