Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Abnormal spindle-like microcephaly-associated protein ASH
Aminoacyl-transfer RNA synthetases class-II family profile
Major facilitator superfamily (MFS) profile
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-119)
NAD(P) transhydrogenase alpha subunit C-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Alpha-glycerophosphate oxidase C-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
tRNA(Ile)-lysidine synthase substrate-binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Resolvase/invertase-type recombinase catalytic
O-(5'-phospho-DNA)-tyrosine intermediate
Phosphoribosylformylglycinamidine synthase linker
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Tryptophan synthase beta chain-like PALP
Activator of Hsp90 ATPase homologue 1-like C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
ATP-dependent DNA helicase RecG C-terminal
Anthranilate synthase component I N-terminal
Polymerase/histidinol phosphatase N-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Glucose-methanol-choline oxidoreductase N-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Lipoprotein-anchoring transpeptidase ErfK/SrfK
RNA polymerase sigma factor 70 region 4 type 2
Glycosyl transferase family 3 N-terminal
Pyridoxamine 5'-phosphate oxidase putative
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
ABC-type glycine betaine transport system substrate-binding
Could play a key role in the communication between the regulatory and the substrate sites
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Shikimate dehydrogenase substrate binding N-terminal
Glycosyltransferase family 28 N-terminal
Thymidylate synthase/dCMP hydroxymethylase
Bacterial Ig-like domain-containing protein
Alpha-L-rhamnosidase six-hairpin glycosidase
Bacterial alpha-L-rhamnosidase N-terminal
Transcription regulator AsnC/Lrp ligand binding
Type II restriction enzyme and methyltransferase RM.Eco57I-like
Formamidopyrimidine-DNA glycosylase catalytic
SMP-30/Gluconolactonase/LRE-like region domain-containing protein
CRISPR-associated protein Cas6 C-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Solute-binding protein family 3/N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Gp5/Type VI secretion system Vgr protein OB-fold
Ribosomal RNA adenine methylase transferase N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Important for beta-aspartyl-AMP intermediate formation
DNA replication/recombination mediator RecO N-terminal
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Penicillin-binding protein transpeptidase
Trigger factor ribosome-binding bacterial
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
YbaK/aminoacyl-tRNA synthetase-associated
Pseudouridine synthase I TruA alpha/beta
Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase C-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Glyoxalase/fosfomycin resistance/dioxygenase
Adaptive response protein AidB N-terminal
DNA polymerase III delta subunit C-terminal
Methionyl-tRNA synthetase anticodon-binding
Glycine cleavage T-protein C-terminal barrel
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Peptide methionine sulphoxide reductase MsrA
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Schiff-base intermediate with D-ribose 5-phosphate
Could be important to modulate the pK values of the two catalytic cysteine residues
Glycoside hydrolase family 31 N-terminal
Schiff-base intermediate with substrate; via topaquinone
N6 adenine-specific DNA methyltransferase N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Carbohydrate-binding domain-containing protein
Isoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-? in acceptor proteins)
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Removed in mature form; by autocatalysis
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Large ribosomal subunit protein uL2 C-terminal
Saccharopine dehydrogenase-like C-terminal
DnaJ homologue subfamily C member 28 conserved
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Threonine/serine exporter-like N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Sporulation transcription regulator WhiA N-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Insecticide toxin TcdB middle/N-terminal domain-containing protein
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
Ribonucleotide reductase large subunit C-terminal
Glycosyl transferase family 28 C-terminal
Essential for prephenate dehydratase activity
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Endoribonuclease L-PSP/chorismate mutase-like
Peptidase M1 membrane alanine aminopeptidase
Inosine monophosphate cyclohydrolase-like
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Large ribosomal subunit protein uL15/eL18
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Contractile injection system tube protein N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Endonuclease/exonuclease/phosphatase domain-containing protein
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Ribulose bisphosphate carboxylase small subunit
Peptidase S9 prolyl oligopeptidase catalytic
Type III restriction enzyme C-terminal endonuclease
Prokaryotic-type class I peptide chain release factors
Schiff-base intermediate with dihydroxyacetone-P
Myo-inositol-1-phosphate synthase GAPDH-like
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Ribose-phosphate pyrophosphokinase N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Glucosamine/galactosamine-6-phosphate isomerase
Survival protein SurE-like phosphatase/nucleotidase
Sugar ABC transporter substrate-binding protein
Large ribosomal subunit protein uL6 alpha-beta
Homogentisate 1,2-dioxygenase C-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
DNA-3-methyladenine glycosylase AlkA N-terminal
Subtilisin-like protease fibronectin type-III
DNA-directed DNA polymerase family A palm
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
EfeO-type cupredoxin-like domain-containing protein
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Heavy metal-binding domain-containing protein
Phosphatidic acid phosphatase type 2/haloperoxidase
Exonuclease VII large subunit C-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Biopterin-dependent aromatic amino acid hydroxylase family profile
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
6-phosphogluconate dehydrogenase C-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Diacylglycerol glucosyltransferase N-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Microcin J25-processing protein McjB C-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
RNA 2-O ribose methyltransferase substrate binding
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
L-seryl-tRNA selenium transferase N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
SsuA/THI5-like domain-containing protein
Bacterial type II secretion system protein E
Alanyl-transfer RNA synthetases family profile
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Fibronectin type-III domain-containing protein
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Small ribosomal subunit protein uS4 N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Mycothiol-dependent maleylpyruvate isomerase metal-binding
Membrane fusion protein biotin-lipoyl like
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Phosphomannose isomerase type I catalytic
Putative regulatory protein FmdB Zinc ribbon
Leucine-binding protein domain-containing protein
NIF system FeS cluster assembly NifU N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
Helix-hairpin-helix DNA-binding motif class 1
BAAT/Acyl-CoA thioester hydrolase C-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Gly-cisPro motif, important for rejection of L-amino acids
Na+/H+ antiporter MnhB subunit-related protein