BREX system Lon protease-like BrxL N-terminal
Bacterial transcription activator effector binding
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Surface layer protein A domain-containing protein
FAD-dependent oxidoreductase 2 FAD binding
DNA primase/polymerase bifunctional N-terminal
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Could be important to modulate the pK values of the two catalytic cysteine residues
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
ssDNA thymidine ADP-ribosyltransferase DarT
Release factor glutamine methyltransferase N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Ribose-phosphate pyrophosphokinase N-terminal
Penicillin-binding protein transpeptidase
O-(3'-phospho-DNA)-tyrosine intermediate
Peptidase metallopeptidase domain-containing protein
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Important for interaction with partner proteins
Menaquinone biosynthesis protein MenD middle
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Single-stranded-DNA-specific exonuclease RecJ C-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
6-phosphogluconate dehydrogenase C-terminal
Peptidase M1 membrane alanine aminopeptidase
Polysaccharide biosynthesis protein C-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Anthranilate synthase component I N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Alpha-D-phosphohexomutase alpha/beta/alpha
Major facilitator superfamily (MFS) profile
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Phosphatidic acid phosphatase type 2/haloperoxidase
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Glycosyltransferase subfamily 4-like N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Phage terminase large subunit C-terminal
Phage terminase large subunit N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
2,4-diaminopentanoate dehydrogenase C-terminal
Dihydrodipicolinate reductase N-terminal
Terminase large subunit-like endonuclease
Probable transposase IS891/IS1136/IS1341
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Putative host cell surface-exposed lipoprotein Ltp-like HTH region
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase N-terminal
Phosphotransferase system enzyme I N-terminal
ABC-type glycine betaine transport system substrate-binding
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Phosphocysteine intermediate; for EIIB activity
Gram-positive cocci surface proteins LPxTG
Gram-positive cocci surface proteins LPxTG domain-containing protein
Glucosamine/galactosamine-6-phosphate isomerase
Inosine/uridine-preferring nucleoside hydrolase
Plays an important role in substrate specificity
Choloylglycine hydrolase/NAAA C-terminal
Solute-binding protein family 3/N-terminal
Solute-binding protein family 3/N-terminal domain-containing protein
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Hydroxymethylglutaryl-coenzyme A synthase C-terminal
Hydroxymethylglutaryl-coenzyme A synthase N-terminal
Large ribosomal subunit protein uL2 C-terminal
RNA 2-O ribose methyltransferase substrate binding
Type I restriction modification DNA specificity
Transposase IS116/IS110/IS902 C-terminal
Peptide methionine sulphoxide reductase MsrA
YbaK/aminoacyl-tRNA synthetase-associated
O-(5'-phospho-DNA)-tyrosine intermediate
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Small ribosomal subunit protein uS4 N-terminal
Important for beta-aspartyl-AMP intermediate formation
Reversibly protonated during proton transport
Involved in allosteric activation by GTP
SUF system FeS cluster assembly SufBD N-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Peptidase M10 metallopeptidase domain-containing protein
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Transcriptional regulator TetR C-terminal Firmicutes type
Dihydrodipicolinate reductase C-terminal
Phosphomannose isomerase type I catalytic
Alpha-glycerophosphate oxidase C-terminal
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Shikimate dehydrogenase substrate binding N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Heat-inducible transcription repressor HrcA C-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain-containing protein
Chromosomal replication initiator protein DnaA
Large ribosomal subunit protein uL6 alpha-beta
Gly-cisPro motif, important for rejection of L-amino acids
Helix-hairpin-helix DNA-binding motif class 1
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Threonine/serine exporter-like N-terminal
Type VII secretion system protein EssD-like
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Bacterial type II secretion system protein E
Cell envelope-related transcriptional attenuator
Alanyl-transfer RNA synthetases family profile
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Thymidylate synthase/dCMP hydroxymethylase
Bacterial bifunctional deaminase-reductase C-terminal
Sporulation transcription regulator WhiA N-terminal
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Important for autoinhibition of adenylyltransferase activity
Tryptophan synthase beta chain-like PALP
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
X-Prolyl dipeptidyl aminopeptidase PepX N-terminal
DNA-directed DNA polymerase family A palm
Carbamoyl-phosphate synthase small subunit N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Phosphoribosylformylglycinamidine synthase linker
Translation elongation factor P/YeiP central
Ionotropic glutamate receptor C-terminal
Cobalamin-independent methionine synthase MetE N-terminal
Large ribosomal subunit protein uL15/eL18
Ribonucleotide reductase large subunit C-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Pseudouridine synthase I TruA alpha/beta
Peptidase C39-like domain-containing protein
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Peptidase S9 prolyl oligopeptidase catalytic
Prokaryotic-type class I peptide chain release factors
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
RNA binding; important for wobble base 34 recognition
Polymerase/histidinol phosphatase N-terminal
Thiamin pyrophosphokinase thiamin-binding
SGNH hydrolase-type esterase domain-containing protein
Glycosyl transferase family 3 N-terminal
Aspartate/homoserine dehydrogenase NAD-binding
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Interaction with polymerase core subunit RpoC
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
ATP synthase F1 complex delta/epsilon subunit N-terminal
Septum formation inhibitor MinC C-terminal
Ribosomal RNA adenine methylase transferase N-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
tRNA pseudouridylate synthase B C-terminal
NIF system FeS cluster assembly NifU N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
DNA replication/recombination mediator RecO N-terminal
Type II restriction enzyme and methyltransferase RM.Eco57I-like
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Restriction system protein Mrr-like N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Exonuclease VII large subunit C-terminal
DNA mismatch repair proteins mutS family
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Conserved hypothetical protein CHP02679 N terminus
Integron-associated effector binding protein
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Signal recognition particle SRP54 helical bundle
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
HicB-like antitoxin of toxin-antitoxin system