S-adenosyl-L-homocysteine hydrolase NAD binding
Aminoacyl-transfer RNA synthetases class-II family profile
Major facilitator superfamily (MFS) profile
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Removed in mature form; by autocatalysis
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Involved in ionization of N3 of dUMP, leading to its activation
Cysteine sulfenic acid (-SOH) intermediate
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Translation elongation factor IF5A C-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
ATP-grasp fold succinyl-CoA synthetase-type
DNA-directed RNA polymerase RBP11-like dimerisation
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Methionyl-tRNA synthetase anticodon-binding
Phosphoribosylformylglycinamidine synthase linker
Cobalamin-independent methionine synthase MetE N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Molybdopterin cofactor biosynthesis C (MoaC)
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
DNA-directed DNA polymerase family B multifunctional
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Alanyl-transfer RNA synthetases family profile
Gamma-glutamylcyclotransferase AIG2-like
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
tRNA nucleotidyltransferase substrate binding
Glycosyl transferase family 3 N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Mandelate racemase/muconate lactonizing enzyme C-terminal
Large ribosomal subunit protein uL2 C-terminal
Proton acceptor; for FBP phosphatase activity
Proton donor/acceptor; for FBP aldolase activity
Schiff-base intermediate with DHAP; for FBP aldolase activity
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Signal recognition particle SRP54 helical bundle
Glycoside hydrolase family 57 N-terminal
Peptidase M1 membrane alanine aminopeptidase
Large ribosomal subunit protein uL6 alpha-beta
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
O-(3'-phospho-DNA)-tyrosine intermediate
Cytochrome b/b6 N-terminal region profile
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Glycoside hydrolase family 31 N-terminal
Cytochrome b/b6 C-terminal region profile
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
NADH:ubiquinone oxidoreductase 30kDa subunit
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Serine/threonine specific protein phosphatases
Ribosome maturation protein SDO1/SBDS C-terminal
Ribosome maturation protein SDO1/SBDS N-terminal
Ribosome maturation protein SDO1/SBDS central
Heme-copper oxidase subunit III family profile
Dinitrogenase iron-molybdenum cofactor biosynthesis
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Peptidase S9 prolyl oligopeptidase catalytic
Large ribosomal subunit protein uL15/eL18
Aconitase A/isopropylmalate dehydratase small subunit swivel
Proton acceptor; for processing activity
Schiff-base intermediate with substrate; via pyruvic acid
Bacterial type II secretion system protein E
Alpha-D-phosphohexomutase alpha/beta/alpha
Cation-transporting P-type ATPase N-terminal
Polyribonucleotide 5'-hydroxyl-kinase Clp1 P-loop
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Inosine/uridine-preferring nucleoside hydrolase
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Tryptophan synthase beta chain-like PALP
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Myo-inositol-1-phosphate synthase GAPDH-like
Pyruvate ferredoxin oxidoreductase beta subunit C-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
SAM-dependent methyltransferase TRM5/TYW2-type
Prepilin type IV endopeptidase peptidase
Glycosyl transferase family 28 C-terminal
Cytochrome oxidase subunit II copper A binding
RNA 3'-terminal phosphate cyclase insert
Iron dependent repressor metal binding and dimerisation
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Schiff-base intermediate with D-ribose 5-phosphate
Glycogen debranching enzyme bacterial and archaeal type N-terminal
Cytochrome c-552/DMSO reductase-like haem-binding
Polymerase/histidinol phosphatase N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Transcription factor NikR nickel binding C-terminal
DNA-directed RNA polymerase subunit 2 hybrid-binding
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
CRISPR-associated protein Cas6 C-terminal
tRNA(Met) cytidine acetyltransferase TmcA N-terminal
Proliferating cell nuclear antigen PCNA C-terminal
Proliferating cell nuclear antigen PCNA N-terminal
Transcription regulator AsnC/Lrp ligand binding
Small zinc finger protein HVO-2753-like zinc-binding pocket
DNA-directed DNA polymerase family B exonuclease
Large ribosomal subunit protein uL30-like ferredoxin-like fold
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
DNA-directed RNA polymerase M/15kDa subunit
Type I restriction enzyme R protein N-terminal
Arsenite oxidase subunit AioA/Iodate reductase subunit IdrA 3Fe-4S cluster
Small ribosomal subunit protein uS15 N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Nicotinate phosphoribosyltransferase C-terminal
Quinolinate phosphoribosyl transferase C-terminal
Electron transfer via tryptophanyl radical
Translation elongation factor EF1B beta/delta subunit guanine nucleotide exchange
Aspartate/homoserine dehydrogenase NAD-binding
Small ribosomal subunit protein uS4 N-terminal
RNA polymerase subunit H/Rpb5 C-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Spo11/DNA topoisomerase VI subunit A N-terminal
ATPsynthase alpha/beta subunit N-terminal extension
Glycine cleavage T-protein C-terminal barrel