Resolvase/invertase-type recombinase catalytic
Peptidase M1 membrane alanine aminopeptidase
Pyridoxamine 5'-phosphate oxidase putative
Thiamine pyrophosphate enzyme TPP-binding
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Mycothiol-dependent maleylpyruvate isomerase metal-binding
Major facilitator superfamily (MFS) profile
Mandelate racemase/muconate lactonizing enzyme C-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Beta-hexosaminidase bacterial type N-terminal
Essential for prephenate dehydratase activity
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Helix-hairpin-helix DNA-binding motif class 1
Polymerase/histidinol phosphatase N-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Aminoacyl-transfer RNA synthetases class-II family profile
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Transcription regulator AsnC/Lrp ligand binding
N,N-dimethylformamidase beta subunit-like C-terminal
Tryptophan synthase beta chain-like PALP
Alpha-glycerophosphate oxidase C-terminal
RNA polymerase sigma factor 70 region 4 type 2
Plays an important role in substrate specificity
Shikimate dehydrogenase substrate binding N-terminal
RlpA-like protein double-psi beta-barrel
RlpA-like protein double-psi beta-barrel domain-containing protein
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Transglycosylase SLT domain-containing protein
Peptidase S9 prolyl oligopeptidase catalytic
Peptidase S9 prolyl oligopeptidase catalytic domain-containing protein
Histidine-specific methyltransferase SAM-dependent
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Cation-transporting P-type ATPase N-terminal
Cytochrome C biogenesis protein transmembrane
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Anthranilate synthase component I N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Membrane insertase YidC/Oxa/ALB C-terminal
Glycosyl transferase family 3 N-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Protein O-mannosyl-transferase C-terminal four TM
Putative exodeoxyribonuclease 8 PDDEXK-like
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Amidohydrolase-related domain-containing protein
Aconitase A/isopropylmalate dehydratase small subunit swivel
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Putative adhesin domain-containing protein
Transposase IS116/IS110/IS902 C-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Putative regulatory protein FmdB Zinc ribbon
Phosphatidic acid phosphatase type 2/haloperoxidase
Alpha-D-phosphohexomutase alpha/beta/alpha
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Cell envelope-related transcriptional attenuator
Large ribosomal subunit protein uL2 C-terminal
DNA primase/polymerase bifunctional N-terminal
Bacterial bifunctional deaminase-reductase C-terminal
DNA-3-methyladenine glycosylase AlkA N-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Putative oxidoreductase/dehydrogenase Rossmann-like
Probable subtilase-type protease inhibitor
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Bulb-type lectin domain-containing protein
Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminal
Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase C-terminal
DNA-directed DNA polymerase family A palm
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
UDP-glucose/GDP-mannose dehydrogenase C-terminal
HTH-type transcriptional regulator MT1864/Rv1816-like C-terminal
Peptidoglycan recognition protein family
Polysaccharide lyase 8 N-terminal alpha-helical
Polysaccharide lyase family 8 C-terminal
Capsule polysaccharide biosynthesis protein
Elongation factor G-binding protein C-terminal treble-clef zinc-finger
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Sporulation transcription regulator WhiA N-terminal
Release factor glutamine methyltransferase N-terminal
Pyrimidine nucleoside phosphorylase C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Cation-transporting P-type ATPase C-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Aerobactin siderophore biosynthesis IucA/IucC N-terminal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Adaptive response protein AidB N-terminal
Transposase IS204/IS1001/IS1096/IS1165 DDE
Probable terminal-alkyne amino-acid exporter
Gfo/Idh/MocA-like oxidoreductase N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
ABC transporter substrate-binding protein PnrA-like
Gfo/Idh/MocA-like oxidoreductase C-terminal
Conserved hypothetical protein CHP02679 N terminus
Penicillin-binding protein transpeptidase
Important for substrate specificity; cannot use PPi as phosphoryl donor
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Involved in ionization of N3 of dUMP, leading to its activation
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
May play a role in metal incorporation in vivo
Lipoprotein-anchoring transpeptidase ErfK/SrfK
Peptide methionine sulphoxide reductase MsrA
Acetylserotonin O-methyltransferase dimerisation
DNA replication/recombination mediator RecO N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Cytochrome bc1 complex cytochrome c subunit
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
YbaK/aminoacyl-tRNA synthetase-associated
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Pyruvate phosphate dikinase AMP/ATP-binding
Peptidase M15C domain-containing protein
Na+/H+ antiporter MnhB subunit-related protein
Diacylglycerol glucosyltransferase N-terminal
Glycoside-hydrolase family GH114 TIM-barrel
Glycoside-hydrolase family GH114 TIM-barrel domain-containing protein
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
Ribonucleotide reductase large subunit C-terminal
Lactate utilization protein B C-terminal
ABC-type glycine betaine transport system substrate-binding
Involved in allosteric activation by GTP
Ricin B lectin domain-containing protein
Ribosomal RNA adenine methylase transferase N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Schiff-base intermediate with substrate; via topaquinone
Gp5/Type VI secretion system Vgr protein OB-fold
Glucose-methanol-choline oxidoreductase N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
NIF system FeS cluster assembly NifU N-terminal
Exonuclease VII large subunit C-terminal
Prokaryotic-type class I peptide chain release factors
M6 family metalloprotease domain-containing protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Large ribosomal subunit protein uL15/eL18
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Microcin J25-processing protein McjB C-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
CobB/CobQ-like glutamine amidotransferase
Threonine/serine exporter-like N-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
PknH-like extracellular domain-containing protein
Cell wall-active antibiotics response LiaF-like C-terminal
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
L-gamma-glutamyl-L-propargylglycine hydroxylase
Glycine cleavage T-protein C-terminal barrel
Transition state stabilizer; via amide nitrogen
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Thiopeptide-type bacteriocin biosynthesis
Fatty acid synthase subunit PfaD N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Phosphomannose isomerase type I catalytic
Terminase large subunit gp17-like C-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
RNA 2-O ribose methyltransferase substrate binding
Formamidopyrimidine-DNA glycosylase catalytic
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
tRNA(Ile)-lysidine synthase substrate-binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Small ribosomal subunit protein uS4 N-terminal
Dystroglycan-type cadherin-like domain-containing protein
4'-phosphopantetheinyl transferase N-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
L,D-transpeptidase catalytic domain-containing protein
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Gram-positive cocci surface proteins LPxTG domain-containing protein
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Glucosamine/galactosamine-6-phosphate isomerase
Important for beta-aspartyl-AMP intermediate formation
Phosphoribosylformylglycinamidine synthase linker
MmyB-like transcription regulator ligand binding
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Nitrite/Sulfite reductase ferredoxin-like
NADH-rubredoxin oxidoreductase C-terminal
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Right handed beta helix domain-containing protein
Myo-inositol-1-phosphate synthase GAPDH-like
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal domain-containing protein
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Signal recognition particle SRP54 helical bundle
6-phosphogluconate dehydrogenase C-terminal
Removed in mature form; by autocatalysis
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Bacterial type II secretion system protein E
Proton acceptor; for glutaminase activity
2-oxoacid dehydrogenase acyltransferase catalytic
Tetracyclin repressor-like C-terminal group 31
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Heat-inducible transcription repressor HrcA C-terminal
Alanyl-transfer RNA synthetases family profile
Translation elongation factor P/YeiP central
Molybdopterin cofactor biosynthesis C (MoaC)
Gram-positive cocci surface proteins LPxTG
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
tRNA pseudouridine synthase II TruB subfamily 2 C-terminal
tRNA pseudouridylate synthase B C-terminal
SGNH hydrolase-type esterase domain-containing protein
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Peptidase C39-like domain-containing protein
Cysteine sulfenic acid (-SOH) intermediate
Inosine/uridine-preferring nucleoside hydrolase
Carbamoyl-phosphate synthase small subunit N-terminal
SUF system FeS cluster assembly SufBD N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
Styrene monooxygenase StyA putative substrate binding
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
S-adenosyl-L-homocysteine hydrolase NAD binding
Schiff-base intermediate with substrate; via pyruvic acid
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-108)
Acyltransferase MbtK/IucB-like conserved
N-acetylmuramoyl-L-alanine amidase domain-containing protein
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Pseudouridine synthase I TruA alpha/beta
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Reversibly protonated during proton transport
N-acetylneuraminic acid synthase N-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Quercetin 2,3-dioxygenase C-terminal cupin
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Schiff-base intermediate with D-ribose 5-phosphate
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Activator of Hsp90 ATPase homologue 1-like C-terminal
Endoribonuclease L-PSP/chorismate mutase-like
Pyruvate dehydrogenase E1 component middle
PsrA tetracyclin repressor-like C-terminal
Prepilin type IV endopeptidase peptidase
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Terminase large subunit-like endonuclease
Cytochrome oxidase subunit II copper A binding
Phosphatidylglycerol lysyltransferase C-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Microcystin LR degradation protein MlrC C-terminal
Microcystin LR degradation protein MlrC N-terminal