A natural polymorphism in Zika virus NS2A protein responsible of virulence in mice.
Biological transmission of arboviruses: reexamination of and new insights into components, mechanisms, and unique traits as well as their evolutionary trends.
C19orf66 interrupts Zika virus replication by inducing lysosomal degradation of viral NS3.
Comparative Flavivirus-Host Protein Interaction Mapping Reveals Mechanisms of Dengue and Zika Virus Pathogenesis.
Crystal structure of Zika virus NS2B-NS3 protease in complex with a boronate inhibitor.
Crystal structure of Zika virus NS5 RNA-dependent RNA polymerase.
Crystal structure of full-length Zika virus NS5 protein reveals a conformation similar to Japanese encephalitis virus NS5.
Crystal structure of unlinked NS2B-NS3 protease from Zika virus.
Crystal structures of the methyltransferase and helicase from the ZIKA 1947 MR766 Uganda strain.
Extended surface for membrane association in Zika virus NS1 structure.
Flavivirus NS1: a multifaceted enigmatic viral protein.
Full-length sequencing and genomic characterization of Bagaza, Kedougou, and Zika viruses.
Host Factor SPCS1 Regulates the Replication of Japanese Encephalitis Virus through Interactions with Transmembrane Domains of NS2B.
Intrinsically disordered side of the zika virus proteome.
Molecular recognition features in zika virus proteome.
Structural Insights into the Inhibition of Zika Virus NS2B-NS3 Protease by a Small-Molecule Inhibitor.
Structural view of the helicase reveals that Zika virus uses a conserved mechanism for unwinding RNA.
Structure and function of the Zika virus full-length NS5 protein.
Structure of the NS3 helicase from Zika virus.
The flavivirus polymerase NS5 regulates translation of viral genomic RNA.
Zika Virus NS5 Forms Supramolecular Nuclear Bodies That Sequester Importin-alpha and Modulate the Host Immune and Pro-Inflammatory Response in Neuronal Cells.
Zika Virus Non-Structural Protein NS5 Inhibits the RIG-I Pathway and Interferon Lambda 1 Promoter Activation by Targeting IKK Epsilon.
Zika Virus Proteins NS2A and NS4A Are Major Antagonists that Reduce IFN-beta Promoter Activity Induced by the MDA5/RIG-I Signaling Pathway.
Zika Virus Targets Human STAT2 to Inhibit Type I Interferon Signaling.
Zika genomics urgently need standardized and curated reference sequences.
Zika virus NS4A and NS4B proteins deregulate Akt-mTOR signaling in human fetal neural stem cells to inhibit neurogenesis and induce autophagy.
Zika virus NS5 protein antagonizes type I interferon production via blocking TBK1 activation.
Zika virus elicits inflammation to evade antiviral response by cleaving cGAS via NS1-caspase-1 axis.
Zika virus evades interferon-mediated antiviral response through the co-operation of multiple nonstructural proteins in vitro.
Zika virus inhibits type-I interferon production and downstream signaling.
Zika virus nonstructural protein 5 residue R681 is critical for dimer formation and enzymatic activity.
Zika-Virus-encoded NS2A disrupts mammalian cortical neurogenesis by degrading adherens junction proteins.