A systematically improved high quality genome and transcriptome of the human blood fluke Schistosoma mansoni.
Mitochondrial genes of Schistosoma mansoni.
Molecular characterization of mitochondrial DNA provides evidence for the recent introduction of Schistosoma mansoni into America.
Phylogenies inferred from mitochondrial gene orders-a cautionary tale from the parasitic flatworms.
Screening the Schistosoma mansoni transcriptome for genes differentially expressed in the schistosomulum stage in search for vaccine candidates.
Molecular and functional characterization of a putative PA28? proteasome activator orthologue in Schistosoma mansoni.
Molecular and functional characterization of a putative PA28gamma proteasome activator orthologue in Schistosoma mansoni.
Schistosoma mansoni Egg, Adult Male and Female Comparative Gene Expression Analysis and Identification of Novel Genes by RNA-Seq.
The major parasite surface antigen associated with human resistance to schistosomiasis is a 37-kD glyceraldehyde-3P-dehydrogenase.
Structure and kinetics assays of recombinant Schistosoma mansoni dihydrofolate reductase.
Molecular cloning and sequencing of the alpha-tubulin gene from Schistosoma mansoni.
The genome of the blood fluke Schistosoma mansoni.
Functional conservation of Schistosoma mansoni Smads in TGF-beta signaling.
Origin and diversification of the human parasite Schistosoma mansoni.
Structure of the gene encoding a putative Schistosoma mansoni tegumental antigen precursor.
Developmentally regulated expression, alternative splicing and distinct sub-groupings in members of the Schistosoma mansoni venom allergen-like (SmVAL) gene family.
Schistosoma mansoni venom allergen-like protein 4 (SmVAL4) is a novel lipid-binding SCP/TAPS protein that lacks the prototypical CAP motifs.
Another 26-kilodalton glutathione S-transferase of Schistosoma mansoni.
Analysis of two Schistosoma mansoni uridine phosphorylases isoforms suggests the emergence of a protein with a non-canonical function.
SmCB2, a novel tegumental cathepsin B from adult Schistosoma mansoni.
Structural and kinetic analysis of Schistosoma mansoni Adenylosuccinate Lyase (SmADSL).
Structure and bioactivity of neuropeptide F from the human parasites Schistosoma mansoni and Schistosoma japonicum.
The class I histone deacetylases of the platyhelminth parasite Schistosoma mansoni.
A cDNA encoding an alpha-tubulin from Schistosoma mansoni.
Expression of functional Schistosoma mansoni Smad4: role in Erk-mediated transforming growth factor beta (TGF-beta) down-regulation.
Schistosoma mansoni: gene expression of the nucleotide excision repair factor 2 (NEF2) during the parasite life cycle, and in adult worms after exposure to different DNA-damaging agents.
Characterisation of a Rho homologue of Schistosoma mansoni.
Activation route of the Schistosoma mansoni cathepsin B1 drug target: structural map with a glycosaminoglycan switch.
Azanitrile Inhibitors of the SmCB1 Protease Target Are Lethal to Schistosoma mansoni: Structural and Mechanistic Insights into Chemotype Reactivity.
Druggable Hot Spots in the Schistosomiasis Cathepsin B1 Target Identified by Functional and Binding Mode Analysis of Potent Vinyl Sulfone Inhibitors.
Functional expression and characterization of Schistosoma mansoni cathepsin B and its trans-activation by an endogenous asparaginyl endopeptidase.
Structural basis for inhibition of cathepsin B drug target from the human blood fluke, Schistosoma mansoni.
Crystal structure of Schistosoma mansoni arginase, a potential drug target for the treatment of schistosomiasis.
Cloning and characterization of a high mobility group box 1 (HMGB1) homologue protein from Schistosoma mansoni.
Cloning the genes and DNA binding properties of High Mobility Group B1 (HMGB1) proteins from the human blood flukes Schistosoma mansoni and Schistosoma japonicum.
Cloning and sequence analysis of a lysophospholipase homologue from Schistosoma mansoni.
Schistosoma mansoni hexokinase: cDNA cloning and immunogenicity studies.
The structure of mammalian hexokinase-1.
Cloning and characterization of a putative calcium-transporting ATPase gene from Schistosoma mansoni.
Cloning of Schistosoma mansoni transcription factor NF-YA subunit: phylogenic conservation of the HAP-2 homology domain.
Molecular cloning and expression of SmIrV1, a Schistosoma mansoni antigen with similarity to calnexin, calreticulin, and OvRal1.
RNA trans-splicing in flatworms. Analysis of trans-spliced mRNAs and genes in the human parasite, Schistosoma mansoni.
Characterization of Sm20.8, a member of a family of schistosome tegumental antigens.
Molecular characterization and immunolocalization of Schistosoma mansoni ATP-diphosphohydrolase.
Molecular Cloning and Characterization of Novel Glutamate-Gated Chloride Channel Subunits from Schistosoma mansoni.
SmCL3, a gastrodermal cysteine protease of the human blood fluke Schistosoma mansoni.
Gene linkage and steady state RNAs suggest trans-splicing may be associated with a polycistronic transcript in Schistosoma mansoni.
Cloning of two actin genes from Schistosoma mansoni.
Cloning of a protein arginine methyltransferase PRMT1 homologue from Schistosoma mansoni: evidence for roles in nuclear receptor signaling and RNA metabolism.
The role of tegumental aquaporin from the human parasitic worm, Schistosoma mansoni, in osmoregulation and drug uptake.
Molecular and enzymatic characterisation of Schistosoma mansoni thioredoxin.
Structural and functional characterization of Schistosoma mansoni Thioredoxin.
Rapamycin insensitivity in Schistosoma mansoni is not due to FKBP12 functionality.
Conserved role for 14-3-3epsilon downstream of type I TGFbeta receptors.
Saci-1, -2, and -3 and Perere, four novel retrotransposons with high transcriptional activities from the human parasite Schistosoma mansoni.
A cloned ATP:guanidino kinase in the trematode Schistosoma mansoni has a novel duplicated structure.
Crystallization and X-ray analysis of the Schistosoma mansoni guanidino kinase.
Molecular determinants of compatibility polymorphism in the Biomphalaria glabrata/Schistosoma mansoni model: New candidates identified by a global comparative proteomics approach.
The Schistosoma mansoni phosphagen kinase gene contains two closely apposed transcription initiation sites and arose from a fused gene duplication.
Cloning of a 21.7-kDa vaccine-dominant antigen gene of Schistosoma mansoni reveals an EF hand-like motif.
The Schistosoma mansoni tegumental-allergen-like (TAL) protein family: influence of developmental expression on human IgE responses.
Structural basis for the function and inhibition of dihydroorotate dehydrogenase from Schistosoma mansoni.
Structural basis for the function and inhibition of dihydroorotate dehydrogenase from Schistosomamansoni.
Structural and kinetic studies of Schistosoma mansoni adenylate kinases.
Characterization of the methionine sulfoxide reductases of Schistosoma mansoni.
Interaction of the proteasome S5a/Rpn10 multiubiquitin-binding protein and the 8 kDa calcium-binding protein of Schistosoma mansoni.
Cloning and functional expression of a Shaker-related voltage-gated potassium channel gene from Schistosoma mansoni (Trematoda: Digenea).
Glutathione reductase and thioredoxin reductase at the crossroad: the structure of Schistosoma mansoni thioredoxin glutathione reductase.
Inhibition of Schistosoma mansoni thioredoxin-glutathione reductase by auranofin: structural and kinetic aspects.
Mapping the catalytic cycle of Schistosoma mansoni thioredoxin glutathione reductase by X-ray crystallography.
Non-covalent inhibitors of thioredoxin glutathione reductase with schistosomicidal activity in vivo.
The disulfide redox system of Schistosoma mansoni and the importance of a multifunctional enzyme, thioredoxin glutathione reductase.
A recombinant protein from Schistosoma mansoni useful for the detection of S. mansoni and Schistosoma haematobium antibodies.
Tegumental phosphodiesterase SmNPP-5 is a virulence factor for schistosomes.
Tegumental phosphosdiesterase SmNPP-5 is a virulence factor for schistosomes.
Identification and characterization of Schistosoma mansoni p17.7, a cyclophilin.
Dioecious Schistosoma mansoni express divergent gene repertoires regulated by pairing.
Cloning and sequence analysis of the Schistosoma mansoni membrane glycoprotein antigen gene GP22.
Cloning and characterization of Schistosoma mansoni fructose-1,6-bisphosphate aldolase isoenzyme.
Crystal structure and immunological properties of the first annexin from Schistosoma mansoni: insights into the structural integrity of the schistosomal tegument.
Characterization of Sm13, a tegumental antigen of Schistosoma mansoni.
Schistosome Na,K-ATPase as a therapeutic target.
Schistosome I/Lamides - A new family of bioactive helminth neuropeptides.
Schistosome I/Lamides--a new family of bioactive helminth neuropeptides.
Biophysical dissection of schistosome septins: Insights into oligomerization and membrane binding.
Crystal structure of a Schistosoma mansoni septin reveals the phenomenon of strand slippage in septins dependent on the nature of the bound nucleotide.
Reversible paralysis of Schistosoma mansoni by forchlorfenuron, a phenylurea cytokinin that affects septins.
Septins of Platyhelminths: identification, phylogeny, expression and localization among developmental stages of Schistosoma mansoni.
Schistosoma mansoni phosphoglycerate mutase: a glycolytic ectoenzyme with thrombolytic potential.
Isolation and characterization of Schistosoma mansoni constitutive androstane receptor.
Molecular identification of a Schistosoma mansoni tegumental protein with similarity to cytoplasmic dynein light chains.
Design, Synthesis, and Characterization of Novel Small Molecules as Broad Range Antischistosomal Agents.
Genetic and molecular basis of drug resistance and species-specific drug action in schistosome parasites.
Independent origins of loss-of-function mutations conferring oxamniquine resistance in a Brazilian schistosome population.
Molecular basis for hycanthone drug action in schistosome parasites.
Structural and Functional Characterization of the Enantiomers of the Antischistosomal Drug Oxamniquine.
Isolation of cDNAs encoding secreted and transmembrane proteins from Schistosoma mansoni by a signal sequence trap method.
Schistosoma mansoni tropomyosin: cDNA characterization, sequence, expression, and gene product localization.
Cloning of a developmentally regulated tegument antigen of Schistosoma mansoni.
Immunization with Schistosoma mansoni 22.6 kDa antigen induces partial protection against experimental infection in a recombinant protein form but not as DNA vaccine.
Molecular cloning and characterisation of the 22-kilodalton adult Schistosoma mansoni antigen recognised by antibodies from mice protectively vaccinated with isolated tegumental surface membranes.
Schistocins: Novel antimicrobial peptides encrypted in the Schistosoma mansoni Kunitz Inhibitor SmKI-1.
Human IgE responses to different splice variants of Schistosoma mansoni tropomyosin: associations with immunity.
Schistosoma mansoni: comparison of cloned tropomyosin antigens shared between adult parasites and Biomphalaria glabrata.
Cloning, characterization, and functional expression of cDNAs encoding glucose transporter proteins from the human parasite Schistosoma mansoni.