Complete genome sequence of the apicomplexan, Cryptosporidium parvum.
Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Structure and function of a G-actin sequestering protein with a vital role in malaria oocyst development inside the mosquito vector.
Characterization of 14-3-3 proteins from Cryptosporidium parvum.
Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis.
Discovery of Potent and Selective Inhibitors of Calcium-Dependent Protein Kinase 1 (CDPK1) from C. parvum and T. gondii.
Structures of apicomplexan calcium-dependent protein kinases reveal mechanism of activation by calcium.
Crystal structures of three protozoan homologs of tryptophanyl-tRNA synthetase.
Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.
Toolkit of Approaches To Support Target-Focused Drug Discovery for Plasmodium falciparum Lysyl tRNA Synthetase.
Characterization of a new phosphatase from Plasmodium.
Integrated mapping, chromosomal sequencing and sequence analysis of Cryptosporidium parvum.
Cryptosporidium parvum spermidine/spermine N1-acetyltransferase exhibits different characteristics from the host enzyme.
Acta Crystallogr Sect F Struct Biol Cryst Commun
Acta Crystallogr. F Struct. Biol. Commun.
Structure of triosephosphate isomerase from Cryptosporidium parvum.
Structure of a critical metabolic enzyme: S-adenosylmethionine synthetase from Cryptosporidium parvum.
An overview of structure, function, and regulation of pyruvate kinases.
Crystal structure of Cryptosporidium parvum pyruvate kinase.
Biochemical and structural characterization of Cryptosporidium parvum Lactate dehydrogenase.
The structural basis of Cryptosporidium-specific IMP dehydrogenase inhibitor selectivity.
Targeting a uniquely nonspecific prenyl synthase with bisphosphonates to combat cryptosporidiosis.