Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii.
Glutathione synthetase homologs encode alpha-L-glutamate ligases for methanogenic coenzyme F420 and tetrahydrosarcinapterin biosyntheses.
A bifunctional dCTP deaminase-dUTP nucleotidohydrolase from the hyperthermophilic archaeon Methanocaldococcus jannaschii.
Structural basis for recognition and catalysis by the bifunctional dCTP deaminase and dUTPase from Methanococcus jannaschii.
Structure of the bifunctional dCTP deaminase-dUTPase from Methanocaldococcus jannaschii and its relation to other homotrimeric dUTPases.
The Methanococcus jannaschii dCTP deaminase is a bifunctional deaminase and diphosphatase.
Structural studies of MJ1529, an O6-methylguanine-DNA methyltransferase.
The Ni-containing carbon monoxide dehydrogenase family: light at the end of the tunnel?
A freestanding proofreading domain is required for protein synthesis quality control in Archaea.
A unique hydrophobic cluster near the active site contributes to differences in borrelidin inhibition among threonyl-tRNA synthetases.
Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Cooperative RNP assembly: complementary rescue of structural defects by protein and RNA subunits of archaeal RNase P.
Fidelity of tRNA 5'-maturation: a possible basis for the functional dependence of archaeal and eukaryal RNase P on multiple protein cofactors.
Studies on Methanocaldococcus jannaschii RNase P reveal insights into the roles of RNA and protein cofactors in RNase P catalysis.
Identifying two ancient enzymes in Archaea using predicted secondary structure alignment.
Toxin-antitoxin loci are highly abundant in free-living but lost from host-associated prokaryotes.
Biochemical characterization of the GTP:adenosylcobinamide-phosphate guanylyltransferase (CobY) enzyme of the hyperthermophilic archaeon Methanocaldococcus jannaschii.
Identification and characterization of the 2-phospho-L-lactate guanylyltransferase involved in coenzyme F420 biosynthesis.
Novel type of ADP-forming acetyl coenzyme A synthetase in hyperthermophilic archaea: heterologous expression and characterization of isoenzymes from the sulfate reducer Archaeoglobus fulgidus and the methanogen Methanococcus jannaschii.
L-aspartate semialdehyde and a 6-deoxy-5-ketohexose 1-phosphate are the precursors to the aromatic amino acids in Methanocaldococcus jannaschii.
MJ0400 from Methanocaldococcus jannaschii exhibits fructose-1,6-bisphosphate aldolase activity.
Structure of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid synthase, a catalyst in the archaeal pathway for the biosynthesis of aromatic amino acids.
Archaeal ribosomal protein L1: the structure provides new insights into RNA binding of the L1 protein family.
Interaction of ribosomal L1 proteins from mesophilic and thermophilic Archaea and Bacteria with specific L1-binding sites on 23S rRNA and mRNA.
Ribosomal protein L1 recognizes the same specific structural motif in its target sites on the autoregulatory mRNA and 23S rRNA.
Structure of ribosomal protein L1 from Methanococcus thermolithotrophicus. Functionally important structural invariants on the L1 surface.
Structural and functional investigation of a putative archaeal selenocysteine synthase.
Evidence for a family of archaeal ATPases.
MJ1647, an open reading frame in the genome of the hyperthermophile Methanococcus jannaschii, encodes a very thermostable archaeal histone with a C-terminal extension.
A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes.
A stable archaeal pyruvate carboxylase from the hyperthermophile Methanococcus jannaschii.
Archaeal RNA polymerase subunits F and P are bona fide homologs of eukaryotic RPB4 and RPB12.
Characterization of nicotinamide mononucleotide adenylyltransferase from thermophilic archaea.
Identification of the archaeal NMN adenylytransferase gene.
Structure of nicotinamide mononucleotide adenylyltransferase: a key enzyme in NAD(+) biosynthesis.
The unusual methanogenic seryl-tRNA synthetase recognizes tRNASer species from all three kingdoms of life.
Amino acid activation of a dual-specificity tRNA synthetase is independent of tRNA.
Asymmetric behavior of archaeal prolyl-tRNA synthetase.
Cysteine activation is an inherent in vitro property of prolyl-tRNA synthetases.
Cysteinyl-tRNA(Cys) formation in Methanocaldococcus jannaschii: the mechanism is still unknown.
Methanocaldococcus jannaschii prolyl-tRNA synthetase charges tRNA(Pro) with cysteine.
Methanococcus jannaschii prolyl-cysteinyl-tRNA synthetase possesses overlapping amino acid binding sites.
One polypeptide with two aminoacyl-tRNA synthetase activities.
Species-specific differences in amino acid editing by class II prolyl-tRNA synthetase.
Synthesis of cysteinyl-tRNA(Cys) by a genome that lacks the normal cysteine-tRNA synthetase.
The structural basis of cysteine aminoacylation of tRNAPro by prolyl-tRNA synthetases.
Crystal structure of the MJ0490 gene product of the hyperthermophilic archaebacterium Methanococcus jannaschii, a novel member of the lactate/malate family of dehydrogenases.
Differences in the oligomeric states of the LDH-like L-MalDH from the hyperthermophilic archaea Methanococcus jannaschii and Archaeoglobus fulgidus.
Identification of an archaeal 2-hydroxy acid dehydrogenase catalyzing reactions involved in coenzyme biosynthesis in methanoarchaea.
Refolding, characterization and crystal structure of (S)-malate dehydrogenase from the hyperthermophilic archaeon Aeropyrum pernix.
The putative L-lactate dehydrogenase from Methanococcus jannaschii is an NADPH-dependent L-malate dehydrogenase.
Atomic structure of the KEOPS complex: an ancient protein kinase-containing molecular machine.
Structure of the archaeal Kae1/Bud32 fusion protein MJ1130: a model for the eukaryotic EKC/KEOPS subcomplex.
CofE catalyzes the addition of two glutamates to F420-0 in F420 coenzyme biosynthesis in Methanococcus jannaschii.
Structure of GlnK1 with bound effectors indicates regulatory mechanism for ammonia uptake.
Crystal structure of the Csm3-Csm4 subcomplex in the type III-A CRISPR-Cas interference complex.
Nucleoside diphosphate kinase from the hyperthermophilic archaeon Methanococcus jannaschii: overexpression, crystallization and preliminary X-ray crystallographic analysis.
A new class of adenylate kinase in methanogens is related to uridylate kinase.
Crystallization and preliminary X-ray diffraction analysis of MJ0458, an adenylate kinase from Methanocaldococcus jannaschii.
Identification of the final two genes functioning in methanofuran biosynthesis in Methanocaldococcus jannaschii.
Crystal structure of a small heat-shock protein.
Small heat shock protein of Methanococcus jannaschii, a hyperthermophile.
Catalytic and thermodynamic properties of tetrahydromethanopterin-dependent serine hydroxymethyltransferase from Methanococcus jannaschii.
Biochemical characterization of a dihydroneopterin aldolase used for methanopterin biosynthesis in methanogens.
Comparative genomics guided discovery of two missing archaeal enzyme families involved in the biosynthesis of the pterin moiety of tetrahydromethanopterin and tetrahydrofolate.
A thermostable platform for transcriptional regulation: the DNA-binding properties of two Lrp homologs from the hyperthermophilic archaeon Methanococcus jannaschii.
The adenylate kinase genes of M. voltae, M. thermolithotrophicus, M. jannaschii, and M. igneus define a new family of adenylate kinases.
The adenylate kinases from a mesophilic and three thermophilic methanogenic members of the Archaea.
Identification of a 5'-deoxyadenosine deaminase in Methanocaldococcus jannaschii and its possible role in recycling the radical S-adenosylmethionine enzyme reaction product 5'-deoxyadenosine.
S-Inosyl-L-Homocysteine Hydrolase, a Novel Enzyme Involved in S-Adenosyl-L-Methionine Recycling.
Structure of triosephosphate isomerase (TIM) from Methanocaldococcus jannaschii.
Identification of lactaldehyde dehydrogenase in Methanocaldococcus jannaschii and its involvement in production of lactate for F420 biosynthesis.
Acetamido sugar biosynthesis in the Euryarchaea.
Characterization of aldolase from Methanococcus jannaschii by gas chromatography.
Kinetic mechanism of fuculose-1-phosphate aldolase from the hyperthermophilic archaeon Methanococcus jannaschii.
Ribose-5-phosphate biosynthesis in Methanocaldococcus jannaschii occurs in the absence of a pentose-phosphate pathway.
The structure of an archaeal ribose-5-phosphate isomerase from Methanocaldococcus jannaschii (MJ1603).
Biosynthesis of wyosine derivatives in tRNA: an ancient and highly diverse pathway in Archaea.
Archaeal RibL: a new FAD synthetase that is air sensitive.
Identification and characterization of the Nudix hydrolase from the Archaeon, Methanococcus jannaschii, as a highly specific ADP-ribose pyrophosphatase.
Binding of adenosine-based ligands to the MjDim1 rRNA methyltransferase: implications for reaction mechanism and drug design.
Structural and functional divergence within the Dim1/KsgA family of rRNA methyltransferases.
A Methanocaldococcus jannaschii archaeal signature gene encodes for a 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase: a new enzyme in purine biosynthesis.
Crystal structure and function of 5-formaminoimidazole-4-carboxamide ribonucleotide synthetase from Methanocaldococcus jannaschii.
The active site of a lon protease from Methanococcus jannaschii distinctly differs from the canonical catalytic Dyad of Lon proteases.
Crystal structure of a fibrillarin homologue from Methanococcus jannaschii, a hyperthermophile, at 1.6-A resolution.
Expression, purification and preliminary X-ray analysis of a fibrillarin homolog from Methanococcus jannaschii, a hyperthermophile.
Biochemical characterization of a novel hypoxanthine/xanthine dNTP pyrophosphatase from Methanococcus jannaschii.
Structure-based identification of a novel NTPase from Methanococcus jannaschii.
Guide-independent DNA cleavage by archaeal Argonaute from Methanocaldococcus jannaschii.
Mechanistic insights into archaeal and human Argonaute substrate binding and cleavage properties.
Single-molecule FRET supports the two-state model of Argonaute action.
Structural and mechanistic insights into an archaeal DNA-guided Argonaute protein.
Panoramic view of a superfamily of phosphatases through substrate profiling.
Structure-based experimental confirmation of biochemical function to a methyltransferase, MJ0882, from hyperthermophile Methanococcus jannaschii.
Crystal structure of the radical SAM enzyme catalyzing tricyclic modified base formation in tRNA.
Pyruvate is the source of the two carbons that are required for formation of the imidazoline ring of 4-demethylwyosine.
Regulation of the protein-conducting channel by a bound ribosome.
Ribosome binding of a single copy of the SecY complex: implications for protein translocation.
Single copies of Sec61 and TRAP associate with a nontranslating mammalian ribosome.
The plug domain of the SecY protein stabilizes the closed state of the translocation channel and maintains a membrane seal.
X-ray structure of a protein-conducting channel.
ATP binding to PAN or the 26S ATPases causes association with the 20S proteasome, gate opening, and translocation of unfolded proteins.
An archaebacterial ATPase, homologous to ATPases in the eukaryotic 26 S proteasome, activates protein breakdown by 20 S proteasomes.
Biochemical and physical properties of the Methanococcus jannaschii 20S proteasome and PAN, a homolog of the ATPase (Rpt) subunits of the eucaryal 26S proteasome.
Docking of the proteasomal ATPases' carboxyl termini in the 20S proteasome's alpha ring opens the gate for substrate entry.
Interactions of PAN's C-termini with archaeal 20S proteasome and implications for the eukaryotic proteasome-ATPase interactions.
Mechanism of substrate unfolding and translocation by the regulatory particle of the proteasome from Methanocaldococcus jannaschii.
PAN, the proteasome-activating nucleotidase from archaebacteria, is a protein-unfolding molecular chaperone.
Structural insights into the regulatory particle of the proteasome from Methanocaldococcus jannaschii.
Crystal structure of a conserved hypothetical protein MJ0927 from Methanocaldococcus jannaschii reveals a novel quaternary assembly in the Nif3 family.
Crystallization and preliminary X-ray diffraction analysis of the Nif3-family protein MJ0927 from Methanocaldococcus jannaschii.
Archaeosortases and exosortases are widely distributed systems linking membrane transit with posttranslational modification.
Identification of a pH regulated Na(+)/H(+) antiporter of Methanococcus jannaschii.
Crystal structure of NusG N-terminal (NGN) domain from Methanocaldococcus jannaschii and its interaction with rpoE''.
Spt4/5 stimulates transcription elongation through the RNA polymerase clamp coiled-coil motif.
(R)-citramalate synthase in methanogenic archaea.
MjK1, a K+ channel from M. jannaschii, mediates K+ uptake and K+ sensitivity in E. coli.
Site-specific mutational analysis of a novel cysteine motif proposed to ligate the 4Fe-4S cluster in the iron-sulfur flavoprotein of the thermophilic methanoarchaeon Methanosarcina thermophila.
Hyperpolarization moves S4 sensors inward to open MVP, a methanococcal voltage-gated potassium channel.
Genes and derived amino acid sequences of S-layer proteins from mesophilic, thermophilic, and extremely thermophilic methanococci.
Methylglyoxal is an intermediate in the biosynthesis of 6-deoxy-5-ketofructose-1-phosphate: a precursor for aromatic amino acid biosynthesis in Methanocaldococcus jannaschii.
Conserved arginine and aspartate residues are critical for function of MjNhaP1, a Na+/H+ antiporter of M. jannaschii.
Crystal structure determination of FtsZ from Methanococcus jannaschii.
Crystal structure of the bacterial cell-division protein ftsZ.
Structural insights into FtsZ protofilament formation.
Structural insights into the conformational variability of FtsZ.
Structural analysis of protein folding by the long-chain archaeal chaperone FKBP26.
Synthesis of catalytically active form III ribulose 1,5-bisphosphate carboxylase/oxygenase in archaea.
Unusual ribulose 1,5-bisphosphate carboxylase/oxygenase of anoxic Archaea.
Cation hexaammines are selective and potent inhibitors of the CorA magnesium transport system.
Functional similarity between archaeal and bacterial CorA magnesium transporters.
Structural insights into the mechanisms of Mg2+ uptake, transport, and gating by CorA.
The CorA Mg2+ transporter is a homotetramer.
The Cryo-EM structure of the CorA channel from Methanocaldococcus jannaschii in low magnesium conditions.
Identification of the gene encoding sulfopyruvate decarboxylase, an enzyme involved in biosynthesis of coenzyme M.
Structural insights into HypB, a GTP-binding protein that regulates metal binding.
A new type of sulfite reductase, a novel coenzyme F420-dependent enzyme, from the methanarchaeon Methanocaldococcus jannaschii.
Coenzyme F420-dependent sulfite reductase-enabled sulfite detoxification and use of sulfite as a sole sulfur source by Methanococcus maripaludis.
Enzymology and evolution of the pyruvate pathway to 2-oxobutyrate in Methanocaldococcus jannaschii.
Methanogen homoaconitase catalyzes both hydrolyase reactions in coenzyme B biosynthesis.
Substrate specificity determinants of the methanogen homoaconitase enzyme: structure and function of the small subunit.
Cloning and expression of the inositol monophosphatase gene from Methanococcus jannaschii and characterization of the enzyme.
Crystal structure and catalytic mechanism of the MJ0109 gene product: a bifunctional enzyme with inositol monophosphatase and fructose 1,6-bisphosphatase activities.
MJ0109 is an enzyme that is both an inositol monophosphatase and the 'missing' archaeal fructose-1,6-bisphosphatase.
Identification and characterization of a DNA primase from the hyperthermophilic archaeon Methanococcus jannaschii.
Identification of a unique radical S-Adenosylmethionine methylase likely involved in methanopterin biosynthesis in Methanocaldococcus jannaschii.
Identification of coenzyme M biosynthetic 2-phosphosulfolactate phosphatase. A member of a new class of Mg2+-dependent acid phosphatases.
An Fe2+-dependent cyclic phosphodiesterase catalyzes the hydrolysis of 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate in methanopterin biosynthesis.
Glucose-6-phosphate isomerase from the hyperthermophilic archaeon Methanococcus jannaschii: characterization of the first archaeal member of the phosphoglucose isomerase superfamily.
Crystal structure of shikimate 5-dehydrogenase (SDH) bound to NADP: insights into function and evolution.
A thermostable single-strand DNase from Methanococcus jannaschii related to the RecJ recombination and repair exonuclease from Escherichia coli.
Alanine Tails Signal Proteolysis in Bacterial Ribosome-Associated Quality Control.
Catalysis by the second class of tRNA(m1G37) methyl transferase requires a conserved proline.
Crystal structure of archaeal tRNA(m(1)G37)methyltransferase aTrm5.
Distinct origins of tRNA(m1G37) methyltransferase.
Mechanism of N-methylation by the tRNA m1G37 methyltransferase Trm5.
Tertiary structure checkpoint at anticodon loop modification in tRNA functional maturation.
Identification of enzymes homologous to isocitrate dehydrogenase that are involved in coenzyme B and leucine biosynthesis in methanoarchaea.
Mechanism of 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase, a key enzyme in the methanopterin biosynthetic pathway.
The conversion of a phenol to an aniline occurs in the biochemical formation of the 1-(4-aminophenyl)-1-deoxy-D-ribitol moiety in methanopterin.
Methanococcus jannaschii ORF mj0608 codes for a class C inorganic pyrophosphatase protected by Co(2+) or Mn(2+) ions against fluoride inhibition.
Structural and functional characterization of a novel phosphodiesterase from Methanococcus jannaschii.
Targeted analysis and discovery of posttranslational modifications in proteins from methanogenic archaea by top-down MS.
RNA polymerase subunit H features a beta-ribbon motif within a novel fold that is present in archaea and eukaryotes.
Crystal structure of archaeal RNase HII: a homologue of human major RNase H.
Metal ion binding and enzymatic mechanism of Methanococcus jannaschii RNase HII.
BeF(3)(-) acts as a phosphate analog in proteins phosphorylated on aspartate: structure of a BeF(3)(-) complex with phosphoserine phosphatase.
Crystal structure of phosphoserine phosphatase from Methanococcus jannaschii, a hyperthermophile, at 1.8 A resolution.
Structural characterization of the reaction pathway in phosphoserine phosphatase: crystallographic 'snapshots' of intermediate states.
Methanococci use the diaminopimelate aminotransferase (DapL) pathway for lysine biosynthesis.
Expression and purification of Arg196 and Lys272 mutants of mevalonate kinase from Methanococcus jannaschii.
Overexpression, purification, and characterization of the thermostable mevalonate kinase from Methanococcus jannaschii.
Structural analysis of a set of proteins resulting from a bacterial genomics project.
Structure of the Methanococcus jannaschii mevalonate kinase, a member of the GHMP kinase superfamily.
Biosynthesis of the 5-(aminomethyl)-3-furanmethanol moiety of methanofuran.
Mechanism of the enzymatic synthesis of 4-(hydroxymethyl)-2-furancarboxaldehyde-phosphate (4-HFC-P) from glyceraldehyde-3-phosphate catalyzed by 4-HFC-P synthase.
Structure of the methanofuran/methanopterin-biosynthetic enzyme MJ1099 from Methanocaldococcus jannaschii.
Structure and function of an archaeal topoisomerase VI subunit with homology to the meiotic recombination factor Spo11.
Crystal structure of the antitoxin-toxin protein complex RelB-RelE from Methanococcus jannaschii.
Identification and characterization of a single-stranded DNA-binding protein from the archaeon Methanococcus jannaschii.
Structure and dynamics of translation initiation factor aIF-1A from the archaeon Methanococcus jannaschii determined by NMR spectroscopy.
Structure and function of the FeoB G-domain from Methanococcus jannaschii.
Structure and activity of the Cas3 HD nuclease MJ0384, an effector enzyme of the CRISPR interference.
Detailed analysis of RNA-protein interactions within the ribosomal protein S8-rRNA complex from the archaeon Methanococcus jannaschii.
A new subfamily of agmatinases present in methanogenic Archaea is Fe(II) dependent.
A thioredoxin from the hyperthermophilic archaeon Methanococcus jannaschii has a glutaredoxin-like fold but thioredoxin-like activities.
Structure and mechanism of homoserine kinase: prototype for the GHMP kinase superfamily.
A monofunctional and thermostable prephenate dehydratase from the archaeon Methanocaldococcus jannaschii.
Biosynthesis of F0, precursor of the F420 cofactor, requires a unique two radical-SAM domain enzyme and tyrosine as substrate.
Biosynthetic versatility and coordinated action of 5'-deoxyadenosyl radicals in deazaflavin biosynthesis.
Identification of the 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase required for coenzyme F(420) biosynthesis.
Cloning, purification, crystallization and preliminary X-ray studies of RFC boxes II-VIII of replication factor C from Methanococcus jannaschii.
Identification of coenzyme M biosynthetic phosphosulfolactate synthase: a new family of sulfonate-biosynthesizing enzymes.
Structure of an archaeal homolog of the eukaryotic RNA polymerase II RPB4/RPB7 complex.
Characterization of an Fe(2+)-dependent archaeal-specific GTP cyclohydrolase, MptA, from Methanocaldococcus jannaschii.
Soluble P-type ATPase from an archaeon, Methanococcus jannaschii.
The Methanocaldococcus jannaschii protein Mj0968 is not a P-type ATPase.
Tetratrico-peptide-repeat proteins in the archaeon Methanococcus jannaschii.
Structure of a two-domain N-terminal fragment of ribosomal protein L10 from Methanococcus jannaschii reveals a specific piece of the archaeal ribosomal stalk.
Expression, purification, characterization and crystallization of flap endonuclease-1 from Methanococcus jannaschii.
Methanococcus jannaschii flap endonuclease: expression, purification, and substrate requirements.
The crystal structure of flap endonuclease-1 from Methanococcus jannaschii.
Crystal structure of DNA sequence specificity subunit of a type I restriction-modification enzyme and its functional implications.
RNA-dependent conversion of phosphoserine forms selenocysteine in eukaryotes and archaea.
A CTP-dependent archaeal riboflavin kinase forms a bridge in the evolution of cradle-loop barrels.
Identification and characterization of an archaeon-specific riboflavin kinase.
Crystallization and preliminary X-ray analysis of the Mj0684 gene product, a putative aspartate aminotransferase, from Methanococcus jannaschii.
A divergent archaeal member of the alkaline phosphatase binuclear metalloenzyme superfamily has phosphoglycerate mutase activity.
Molecular characterization of phosphoglycerate mutase in archaea.
Crystal structures of apo wild-type M. jannaschii tyrosyl-tRNA synthetase (TyrRS) and an engineered TyrRS specific for O-methyl-L-tyrosine.
Domain-domain communication in a miniature archaebacterial tRNA synthetase.
Major anticodon-binding region missing from an archaebacterial tRNA synthetase.
Structural basis for orthogonal tRNA specificities of tyrosyl-tRNA synthetases for genetic code expansion.
Alpha-keto acid chain elongation reactions involved in the biosynthesis of coenzyme B (7-mercaptoheptanoyl threonine phosphate) in methanogenic Archaea.
A member of a new class of GTP cyclohydrolases produces formylaminopyrimidine nucleotide monophosphates.
Archaeal ApbC/Nbp35 homologs function as iron-sulfur cluster carrier proteins.
Crystallization and preliminary X-ray analysis of isopentenyl diphosphate isomerase from Methanocaldococcus jannaschii.
Inhibition of type 2 isopentenyl diphosphate isomerase from Methanocaldococcus jannaschii by a mechanism-based inhibitor of type 1 isopentenyl diphosphate isomerase.
ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer.
The crystal structure of the MJ0796 ATP-binding cassette. Implications for the structural consequences of ATP hydrolysis in the active site of an ABC transporter.
Archaeal shikimate kinase, a new member of the GHMP-kinase family.
Aminoacylation of tRNA with phosphoserine for synthesis of cysteinyl-tRNA(Cys).
RNA-dependent cysteine biosynthesis in archaea.
Structural insights into the first step of RNA-dependent cysteine biosynthesis in archaea.
A mechanism of regulating transmembrane potassium flux through a ligand-mediated conformational switch.
Catalytic properties of the archaeal S-adenosylmethionine decarboxylase from Methanococcus jannaschii.
S-adenosylmethionine decarboxylase from the archaeon Methanococcus jannaschii: identification of a novel family of pyruvoyl enzymes.
Structure of dihydrodipicolinate synthase from Methanocaldococcus jannaschii.
Backbone resonance assignments of the 48 kDa dimeric putative 18S rRNA-methyltransferase Nep1 from Methanocaldococcus jannaschii.
The crystal structure of Nep1 reveals an extended SPOUT-class methyltransferase fold and a pre-organized SAM-binding site.
The ribosome assembly factor Nep1 responsible for Bowen-Conradi syndrome is a pseudouridine-N1-specific methyltransferase.
Cyclic di-AMP: another second messenger enters the fray.
RNA-based fluorescent biosensors for live cell imaging of second messenger cyclic di-AMP.
Identification of a highly diverged class of S-adenosylmethionine synthetases in the archaea.
The mcrA gene as an alternative to 16S rRNA in the phylogenetic analysis of methanogen populations in landfill.
Characterization of the aspartate transcarbamoylase from Methanococcus jannaschii.
Crystallization and structure determination of the catalytic trimer of Methanococcus jannaschii aspartate transcarbamoylase.
Characterization and kinetic mechanism of mono- and bifunctional ornithine acetyltransferases from thermophilic microorganisms.
Methanocaldococcus jannaschii uses a modified mevalonate pathway for biosynthesis of isopentenyl diphosphate.
Mutation of archaeal isopentenyl phosphate kinase highlights mechanism and guides phosphorylation of additional isoprenoid monophosphates.
X-ray structure of translation initiation factor eIF2gamma: implications for tRNA and eIF2alpha binding.
Iron-sulfur flavoprotein (Isf) from Methanosarcina thermophila is the prototype of a widely distributed family.
Structure of a site-2 protease family intramembrane metalloprotease.
Crystal structure of Mj1640/DUF358 protein reveals a putative SPOUT-class RNA methyltransferase.
Identification of the enzyme responsible for N1-methylation of pseudouridine 54 in archaeal tRNAs.
The archaeal COG1901/DUF358 SPOUT-methyltransferase members, together with pseudouridine synthase Pus10, catalyze the formation of 1-methylpseudouridine at position 54 of tRNA.
Crystal structures of eukaryotic translation initiation factor 5A from Methanococcus jannaschii at 1.8-A resolution.
Universally conserved translation initiation factors.
Biosynthesis of riboflavin in archaea studies on the mechanism of 3,4-dihydroxy-2-butanone-4-phosphate synthase of Methanococcus jannaschii.
Metal sites in 3,4-dihydroxy-2-butanone 4-phosphate synthase from Methanococcus jannaschii in complex with the substrate ribulose 5-phosphate.
Structure of 3,4-dihydroxy-2-butanone 4-phosphate synthase from Methanococcus jannaschii in complex with divalent metal ions and the substrate ribulose 5-phosphate: implications for the catalytic mechanism.
New class of IMP cyclohydrolases in Methanococcus jannaschii.
Structural and functional differences between two homologous mechanosensitive channels of Methanococcus jannaschii.
Formation of m2G6 in Methanocaldococcus jannaschii tRNA catalyzed by the novel methyltransferase Trm14.
Structure of protein L7Ae bound to a K-turn derived from an archaeal box H/ACA sRNA at 1.8 A resolution.
The crystal structure of the Methanocaldococcus jannaschii multifunctional L7Ae RNA-binding protein reveals an induced-fit interaction with the box C/D RNAs.
Methanococcus jannaschii uses a pyruvoyl-dependent arginine decarboxylase in polyamine biosynthesis.