Assembly of a phased diploid Candida albicans genome facilitates allele-specific measurements and provides a simple model for repeat and indel structure.
Assembly of the Candida albicans genome into sixteen supercontigs aligned on the eight chromosomes.
The diploid genome sequence of Candida albicans.
Autophagy in the pathogen Candida albicans.
Crystal structures of Hsp104 N-terminal domains from Saccharomyces cerevisiae and Candida albicans suggest the mechanism for the function of Hsp104 in dissolving prions.
Candida albicans Iff11, a secreted protein required for cell wall structure and virulence.
Cap2-HAP complex is a critical transcriptional regulator that has dual but contrasting roles in regulation of iron homeostasis in Candida albicans.
Genome-wide identification of fungal GPI proteins.
Integrated proteomics and genomics strategies bring new insight into Candida albicans response upon macrophage interaction.
Temporal anatomy of an epigenetic switch in cell programming: the white-opaque transition of C. albicans.
Unexpected role for a serine/threonine-rich domain in the Candida albicans Iff protein family.
An expanded regulatory network temporally controls Candida albicans biofilm formation.
Characterization of the CaNAG3, CaNAG4, and CaNAG6 genes of the pathogenic fungus Candida albicans: possible involvement of these genes in the susceptibilities of cytotoxic agents.
Identification and characterization of the genes for N-acetylglucosamine kinase and N-acetylglucosamine-phosphate deacetylase in the pathogenic fungus Candida albicans.
N-acetylglucosamine utilization by Saccharomyces cerevisiae based on expression of Candida albicans NAG genes.
Two membrane proteins located in the Nag regulon of Candida albicans confer multidrug resistance.
Exposure of Candida albicans to antifungal agents affects expression of SAP2 and SAP9 secreted proteinase genes.
The Golgi GDPase of the fungal pathogen Candida albicans affects morphogenesis, glycosylation, and cell wall properties.
Rieske head domain dynamics and indazole-derivative inhibition of Candida albicans complex III.
Sequence finishing and gene mapping for Candida albicans chromosome 7 and syntenic analysis against the Saccharomyces cerevisiae genome.
The IQGAP Iqg1 is a regulatory target of CDK for cytokinesis in Candida albicans.
Time course global gene expression analysis of an in vivo Candida biofilm.
A family of secreted pathogenesis-related proteins in Candida albicans.
Corneal virulence of Candida albicans strains deficient in Tup1-regulated genes.
Effects of fluconazole on the secretome, the wall proteome, and wall integrity of the clinical fungus Candida albicans.
Efg1, a morphogenetic regulator in Candida albicans, is a sequence-specific DNA binding protein.
Identification and characterization of TUP1-regulated genes in Candida albicans.
Identification of Candida albicans exposed surface proteins in vivo by a rapid proteomic approach.
Immunoglobulin G responses to a panel of Candida albicans antigens as accurate and early markers for the presence of systemic candidiasis.
Normal adaptation of Candida albicans to the murine gastrointestinal tract requires Efg1p-dependent regulation of metabolic and host defense genes.
Rfg1, a protein related to the Saccharomyces cerevisiae hypoxic regulator Rox1, controls filamentous growth and virulence in Candida albicans.
TUP1, CPH1 and EFG1 make independent contributions to filamentation in Candida albicans.
The basic helix-loop-helix transcription factor Cph2 regulates hyphal development in Candida albicans partly via TEC1.
Transcription profiling of Candida albicans cells undergoing the yeast-to-hyphal transition.
E-site drug specificity of the human pathogen Candida albicans ribosome.
FungalRV: adhesin prediction and immunoinformatics portal for human fungal pathogens.
Global roles of Ssn6 in Tup1- and Nrg1-dependent gene regulation in the fungal pathogen, Candida albicans.
A phenotypic profile of the Candida albicans regulatory network.
An iron homeostasis regulatory circuit with reciprocal roles in Candida albicans commensalism and pathogenesis.
In silico analysis for transcription factors with Zn(II)(2)C(6) binuclear cluster DNA-binding domains in Candida albicans.
In vivo systematic analysis of Candida albicans Zn2-Cys6 transcription factors mutants for mice organ colonization.
Post-transcriptional regulation of the Sef1 transcription factor controls the virulence of Candida albicans in its mammalian host.
Regulatory network modelling of iron acquisition by a fungal pathogen in contact with epithelial cells.
Regulatory networks affected by iron availability in Candida albicans.
A novel role for the transcription factor Cwt1p as a negative regulator of nitrosative stress in Candida albicans.
Analysis of PRA1 and its relationship to Candida albicans- macrophage interactions.
CTA4 transcription factor mediates induction of nitrosative stress response in Candida albicans.
Candida albicans Hap43 is a repressor induced under low-iron conditions and is essential for iron-responsive transcriptional regulation and virulence.
Cellular responses of Candida albicans to phagocytosis and the extracellular activities of neutrophils are critical to counteract carbohydrate starvation, oxidative and nitrosative stress.
Fluconazole at subinhibitory concentrations induces the oxidative- and nitrosative-responsive genes TRR1, GRE2 and YHB1, and enhances the resistance of Candida albicans to phagocytes.
Imidazole antibiotics inhibit the nitric oxide dioxygenase function of microbial flavohemoglobin.
In vivo transcript profiling of Candida albicans identifies a gene essential for interepithelial dissemination.
Inducible defense mechanism against nitric oxide in Candida albicans.
Transcriptional response of Candida albicans to nitric oxide and the role of the YHB1 gene in nitrosative stress and virulence.
Transcriptional response of Candida albicans upon internalization by macrophages.
A recently evolved transcriptional network controls biofilm development in Candida albicans.
Calcineurin is essential for survival during membrane stress in Candida albicans.
Purification, characterization and inhibition of sterol C24-methyltransferase from Candida albicans.
Quantitative proteomics and metabolomics approaches to demonstrate N-acetyl-D-glucosamine inducible amino acid deprivation response as morphological switch in Candida albicans.
Sequencing, disruption, and characterization of the Candida albicans sterol methyltransferase (ERG6) gene: drug susceptibility studies in erg6 mutants.
Antifungal activity of fluconazole in combination with lovastatin and their effects on gene expression in the ergosterol and prenylation pathways in Candida albicans.
A 368-base-pair cis-acting HWP1 promoter region, HCR, of Candida albicans confers hypha-specific gene regulation and binds architectural transcription factors Nhp6 and Gcf1p.
Adhesive and mammalian transglutaminase substrate properties of Candida albicans Hwp1.
An in vitro assay to study the transcriptional response during adherence of Candida albicans to different human epithelia.
Beta-1,2 oligomannose adhesin epitopes are widely distributed over the different families of Candida albicans cell wall mannoproteins and are associated through both N- and O-glycosylation processes.
C-terminal signals regulate targeting of glycosylphosphatidylinositol-anchored proteins to the cell wall or plasma membrane in Candida albicans.
Candida albicans HWP1 gene expression and host antibody responses in colonization and disease.
Candida albicans Tup1 is involved in farnesol-mediated inhibition of filamentous-growth induction.
Capric acid secreted by S. boulardii inhibits C. albicans filamentous growth, adhesion and biofilm formation.
Chemical screening identifies filastatin, a small molecule inhibitor of Candida albicans adhesion, morphogenesis, and pathogenesis.
Comparison between allicin and fluconazole in Candida albicans biofilm inhibition and in suppression of HWP1 gene expression.
Critical role of Bcr1-dependent adhesins in C. albicans biofilm formation in vitro and in vivo.
Developmental expression of a tandemly repeated, proline- and glutamine-rich amino acid motif on hyphal surfaces on Candida albicans.
Diagnosis of invasive candidiasis by enzyme-linked immunosorbent assay using the N-terminal fragment of Candida albicans hyphal wall protein 1.
Essential role of the Candida albicans transglutaminase substrate, hyphal wall protein 1, in lethal oroesophageal candidiasis in immunodeficient mice.
Expression of ALS1, HWP1 and SAP4 genes in Candida albicans strains isolated from women with vaginitis.
Expression of firefly luciferase in Candida albicans and its use in the selection of stable transformants.
Expression of transglutaminase substrate activity on Candida albicans germ tubes through a coiled, disulfide-bonded N-terminal domain of Hwp1 requires C-terminal glycosylphosphatidylinositol modification.
Function of Candida albicans adhesin Hwp1 in biofilm formation.
Functional analysis of Candida albicans GPI-anchored proteins: roles in cell wall integrity and caspofungin sensitivity.
Genetic organization and sequence analysis of the hypha-specific cell wall protein gene HWP1 of Candida albicans.
Gpr1, a putative G-protein-coupled receptor, regulates morphogenesis and hypha formation in the pathogenic fungus Candida albicans.
HWP1 functions in the morphological development of Candida albicans downstream of EFG1, TUP1, and RBF1.
Hemoglobin is an effective inducer of hyphal differentiation in Candida albicans.
Heterologous expression of Candida albicans cell wall-associated adhesins in Saccharomyces cerevisiae Reveals differential specificities in adherence and biofilm formation and in binding oral Streptococcus gordonii.
Human serum promotes Candida albicans biofilm growth and virulence gene expression on silicone biomaterial.
Hwp1 and related adhesins contribute to both mating and biofilm formation in Candida albicans.
Hypoxic conditions and iron restriction affect the cell-wall proteome of Candida albicans grown under vagina-simulative conditions.
Identification of inhibitors of yeast-to-hyphae transition in Candida albicans by a reporter screening assay.
Inactivation of Kex2p diminishes the virulence of Candida albicans.
Inhibition of Candida albicans biofilm formation by farnesol, a quorum-sensing molecule.
Inhibition of yeast-to-hypha transition in Candida albicans by phorbasin H isolated from Phorbas sp.
Inhibition on Candida albicans biofilm formation using divalent cation chelators (EDTA).
Interaction of Candida albicans biofilms with antifungals: transcriptional response and binding of antifungals to beta-glucans.
Mass spectrometric quantification of the adaptations in the wall proteome of Candida albicans in response to ambient pH.
Mss11, a transcriptional activator, is required for hyphal development in Candida albicans.
Niche-specific requirement for hyphal wall protein 1 in virulence of Candida albicans.
Ocimum sanctum essential oil inhibits virulence attributes in Candida albicans.
Purpurin suppresses Candida albicans biofilm formation and hyphal development.
Reduced virulence of HWP1-deficient mutants of Candida albicans and their interactions with host cells.
Reevaluation of the role of HWP1 in systemic candidiasis by use of Candida albicans strains with selectable marker URA3 targeted to the ENO1 locus.
Regulation of cell-surface genes and biofilm formation by the C. albicans transcription factor Bcr1p.
Role of Bcr1-activated genes Hwp1 and Hyr1 in Candida albicans oral mucosal biofilms and neutrophil evasion.
State of differentiation defines buccal epithelial cell affinity for cross-linking to Candida albicans Hwp1.
Streptococcus mutans inhibits Candida albicans hyphal formation by the fatty acid signaling molecule trans-2-decenoic acid (SDSF).
Synthetic glycopeptide vaccines combining beta-mannan and peptide epitopes induce protection against candidiasis.
The Flo8 transcription factor is essential for hyphal development and virulence in Candida albicans.
The adhesin Hwp1 and the first daughter cell localize to the a/a portion of the conjugation bridge during Candida albicans mating.
The inhibitory activity of linalool against the filamentous growth and biofilm formation in Candida albicans.
The inhibitory effect of a macrocyclic bisbibenzyl riccardin D on the biofilms of Candida albicans.
Transcript profiling in Candida albicans reveals new cellular functions for the transcriptional repressors CaTup1, CaMig1 and CaNrg1.
Trifluoromethanesulfonic acid-based proteomic analysis of cell wall and secreted proteins of the ascomycetous fungi Neurospora crassa and Candida albicans.
Use of green fluorescent protein fusions to analyse the N- and C-terminal signal peptides of GPI-anchored cell wall proteins in Candida albicans.
A study of the Candida albicans cell wall proteome.
Contribution of the glycolytic flux and hypoxia adaptation to efficient biofilm formation by Candida albicans.
Control of the C. albicans cell wall damage response by transcriptional regulator Cas5.
Role of the Hog1 stress-activated protein kinase in the global transcriptional response to stress in the fungal pathogen Candida albicans.
A conserved transcriptional regulator governs fungal morphology in widely diverged species.
Bistable expression of WOR1, a master regulator of white-opaque switching in Candida albicans.
Environmental induction of white-opaque switching in Candida albicans.
Epigenetic properties of white-opaque switching in Candida albicans are based on a self-sustaining transcriptional feedback loop.
Identification of Candida albicans genes that induce Saccharomyces cerevisiae cell adhesion and morphogenesis.
Interlocking transcriptional feedback loops control white-opaque switching in Candida albicans.
TOS9 regulates white-opaque switching in Candida albicans.
The transcription factor Flo8 mediates CO2 sensing in the human fungal pathogen Candida albicans.
An extensive circuitry for cell wall regulation in Candida albicans.
Derepressed hyphal growth and reduced virulence in a VH1 family-related protein phosphatase mutant of the human pathogen Candida albicans.
Reduced pathogenicity of a Candida albicans MAP kinase phosphatase (CPP1) mutant in the murine mastitis model.
Repression of hyphal proteinase expression by the mitogen-activated protein (MAP) kinase phosphatase Cpp1p of Candida albicans is independent of the MAP kinase Cek1p.
Roles of the Candida albicans mitogen-activated protein kinase homolog, Cek1p, in hyphal development and systemic candidiasis.
Candida albicans SET1 encodes a histone 3 lysine 4 methyltransferase that contributes to the pathogenesis of invasive candidiasis.
Identification and functional characterization of a novel Candida albicans gene CaMNN5 that suppresses the iron-dependent growth defect of Saccharomyces cerevisiae aft1Delta mutant.
MNN5 encodes an iron-regulated alpha-1,2-mannosyltransferase important for protein glycosylation, cell wall integrity, morphogenesis, and virulence in Candida albicans.
The Mnn2 mannosyltransferase family modulates mannoprotein fibril length, immune recognition and virulence of Candida albicans.
A photostable green fluorescent protein variant for analysis of protein localization in Candida albicans.
Candida albicans hyphal morphogenesis occurs in Sec3p-independent and Sec3p-dependent phases separated by septin ring formation.
Candida albicans protein kinase CaHsl1p regulates cell elongation and virulence.
Candida albicans septin mutants are defective for invasive growth and virulence.
Cell cycle dynamics and quorum sensing in Candida albicans chlamydospores are distinct from budding and hyphal growth.
Cyclin-dependent kinases control septin phosphorylation in Candida albicans hyphal development.
Rapid redistribution of phosphatidylinositol-(4,5)-bisphosphate and septins during the Candida albicans response to caspofungin.
Septin function in Candida albicans morphogenesis.
Tandem affinity purification of the Candida albicans septin protein complex.
The germ tubes of Candida albicans hyphae and pseudohyphae show different patterns of septin ring localization.
Function of Atg11 in non-selective autophagy and selective autophagy of Candida albicans.
Identification and characterization of CaApe2 -- a neutral arginine/alanine/leucine-specific metallo-aminopeptidase from Candida albicans.
Characterization of the Candida albicans amino acid permease family: Gap2 is the only general amino acid permease and Gap4 is an S-adenosylmethionine (SAM) transporter required for SAM-induced morphogenesis.
Functional analysis of the phospholipase C gene CaPLC1 and two unusual phospholipase C genes, CaPLC2 and CaPLC3, of Candida albicans.
Global role of the protein kinase Gcn2 in the human pathogen Candida albicans.
The Candida albicans GAP gene family encodes permeases involved in general and specific amino acid uptake and sensing.
A comprehensive functional portrait of two heat shock factor-type transcriptional regulators involved in Candida albicans morphogenesis and virulence.
A histone deacetylase adjusts transcription kinetics at coding sequences during Candida albicans morphogenesis.
A sticky situation: untangling the transcriptional network controlling biofilm development in Candida albicans.
Adaptations of Candida albicans for growth in the mammalian intestinal tract.
Bcr1 plays a central role in the regulation of opaque cell filamentation in Candida albicans.
Conjugated linoleic acid inhibits hyphal growth in Candida albicans by modulating Ras1p cellular levels and downregulating TEC1 expression.
DNA array studies demonstrate convergent regulation of virulence factors by Cph1, Cph2, and Efg1 in Candida albicans.
Developmental regulation of an adhesin gene during cellular morphogenesis in the fungal pathogen Candida albicans.
Divergent targets of Candida albicans biofilm regulator Bcr1 in vitro and in vivo.
Effect of tetrandrine against Candida albicans biofilms.
From attachment to damage: defined genes of Candida albicans mediate adhesion, invasion and damage during interaction with oral epithelial cells.
Genetic control of conventional and pheromone-stimulated biofilm formation in Candida albicans.
Hypoxic adaptation by Efg1 regulates biofilm formation by Candida albicans.
Killing of Candida albicans filaments by Salmonella enterica serovar Typhimurium is mediated by sopB effectors, parts of a type III secretion system.
PGA4, a GAS homologue from Candida albicans, is up-regulated early in infection processes.
Pseudomonas aeruginosa secreted factors impair biofilm development in Candida albicans.
Regulation of the Cdc42/Cdc24 GTPase module during Candida albicans hyphal growth.
Repression of CDC28 reduces the expression of the morphology-related transcription factors, Efg1p, Nrg1p, Rbf1p, Rim101p, Fkh2p and Tec1p and induces cell elongation in Candida albicans.
Role of filamentation in Galleria mellonella killing by Candida albicans.
Roles of Candida albicans Gat2, a GATA-type zinc finger transcription factor, in biofilm formation, filamentous growth and virulence.
Secretory products of Escherichia coli biofilm modulate Candida biofilm formation and hyphal development.
Tec1 mediates the pheromone response of the white phenotype of Candida albicans: insights into the evolution of new signal transduction pathways.
Tec1p-independent activation of a hypha-associated Candida albicans virulence gene during infection.
The 'finger,' a unique multicellular morphology of Candida albicans induced by CO2 and dependent upon the Ras1-cyclic AMP pathway.
The Mep2p ammonium permease controls nitrogen starvation-induced filamentous growth in Candida albicans.
The TEA/ATTS transcription factor CaTec1p regulates hyphal development and virulence in Candida albicans.
The protein kinase Tor1 regulates adhesin gene expression in Candida albicans.
Candida albicans Czf1 and Efg1 coordinate the response to farnesol during quorum sensing, white-opaque thermal dimorphism, and cell death.
Divergence of Stp1 and Stp2 transcription factors in Candida albicans places virulence factors required for proper nutrient acquisition under amino acid control.
Pho85, Pcl1, and Hms1 signaling governs Candida albicans morphogenesis induced by high temperature or Hsp90 compromise.
The fungal pathogen Candida albicans autoinduces hyphal morphogenesis by raising extracellular pH.
Wild-type Drosophila melanogaster as a model host to analyze nitrogen source dependent virulence of Candida albicans.
A novel multidrug efflux transporter gene of the major facilitator superfamily from Candida albicans (FLU1) conferring resistance to fluconazole.
Alcohol dehydrogenase I expression correlates with CDR1, CDR2 and FLU1 expression in Candida albicans from patients with vulvovaginal candidiasis.
An acquired mechanism of antifungal drug resistance simultaneously enables Candida albicans to escape from intrinsic host defenses.
Candida albicans flu1-mediated efflux of salivary histatin 5 reduces its cytosolic concentration and fungicidal activity.
Identification of the Candida albicans Cap1p regulon.
Mechanism of action of tetrandrine, a natural inhibitor of Candida albicans drug efflux pumps.
Molecular mechanisms underlying the tetrandrine-mediated reversal of the fluconazole resistance of Candida albicans.
Sensitive bioassay for determination of fluconazole concentrations in plasma using a Candida albicans mutant hypersusceptible to azoles.
Vulvovaginal candidiasis: species distribution, fluconazole resistance and drug efflux pump gene overexpression.
Genetic control of chlamydospore formation in Candida albicans.
Characterisation of Pga1, a putative Candida albicans cell wall protein necessary for proper adhesion and biofilm formation.
Genomic response programs of Candida albicans following protoplasting and regeneration.
Candida albicans specific genes: distinct roles in host-pathogen interactions.
Comparison of gene expression profiles of Candida albicans azole-resistant clinical isolates and laboratory strains exposed to drugs inducing multidrug transporters.
Depletion of polyubiquitin encoded by the UBI4 gene confers pleiotropic phenotype to Candida albicans cells.
Molecular and proteomic analyses highlight the importance of ubiquitination for the stress resistance, metabolic adaptation, morphogenetic regulation and virulence of Candida albicans.
Mnt1p and Mnt2p of Candida albicans are partially redundant alpha-1,2-mannosyltransferases that participate in O-linked mannosylation and are required for adhesion and virulence.
MFS transportome of the human pathogenic yeast Candida albicans.
Novel role of a family of major facilitator transporters in biofilm development and virulence of Candida albicans.
Characterization of genetic determinants that modulate Candida albicans filamentation in the presence of bacteria.
Milbemycins: more than efflux inhibitors for fungal pathogens.
Processing of predicted substrates of fungal Kex2 proteinases from Candida albicans, C. glabrata, Saccharomyces cerevisiae and Pichia pastoris.
Glycine metabolism in Candida albicans: characterization of the serine hydroxymethyltransferase (SHM1, SHM2) and threonine aldolase (GLY1) genes.
Proteomics-based identification of novel Candida albicans antigens for diagnosis of systemic candidiasis in patients with underlying hematological malignancies.
A conserved stress-activated protein kinase regulates a core stress response in the human pathogen Candida albicans.
Candida albicans response regulator gene SSK1 regulates a subset of genes whose functions are associated with cell wall biosynthesis and adaptation to oxidative stress.
Functional studies of the Ssk1p response regulator protein of Candida albicans as determined by phenotypic analysis of receiver domain point mutants.
Role of the mitogen-activated protein kinase Hog1p in morphogenesis and virulence of Candida albicans.
The Cek1 and Hog1 mitogen-activated protein kinases play complementary roles in cell wall biogenesis and chlamydospore formation in the fungal pathogen Candida albicans.
The Hog1 mitogen-activated protein kinase is essential in the oxidative stress response and chlamydospore formation in Candida albicans.
The MAP kinase Hog1p differentially regulates stress-induced production and accumulation of glycerol and D-arabitol in Candida albicans.
The MAP kinase Mkc1p is activated under different stress conditions in Candida albicans.
The Pbs2 MAP kinase kinase is essential for the oxidative-stress response in the fungal pathogen Candida albicans.
The mitogen-activated protein kinase homolog HOG1 gene controls glycerol accumulation in the pathogenic fungus Candida albicans.
Candida albicans uses multiple mechanisms to acquire the essential metabolite inositol during infection.
Candida albicans Ssa1/2p is the cell envelope binding protein for human salivary histatin 5.
Evidence for presence in the cell wall of Candida albicans of a protein related to the hsp70 family.
Glycerophosphocholine utilization by Candida albicans: role of the Git3 transporter in virulence.
Property differences among the four major Candida albicans strain clades.
Robust utilization of phospholipase-generated metabolites, glycerophosphodiesters, by Candida albicans: role of the CaGit1 permease.
Cross-species identification of novel Candida albicans immunogenic proteins by combination of two-dimensional polyacrylamide gel electrophoresis and mass spectrometry.
MNL1 regulates weak acid-induced stress responses of the fungal pathogen Candida albicans.
Msn2- and Msn4-like transcription factors play no obvious roles in the stress responses of the fungal pathogen Candida albicans.
Genome-wide expression profiling of the response to azole, polyene, echinocandin, and pyrimidine antifungal agents in Candida albicans.
Genome-wide expression profiling reveals genes associated with amphotericin B and fluconazole resistance in experimentally induced antifungal resistant isolates of Candida albicans.
Regulation of sugar transport and metabolism by the Candida albicans Rgt1 transcriptional repressor.
Transcriptional regulation of carbohydrate metabolism in the human pathogen Candida albicans.
Unique aspects of gene expression during Candida albicans mating and possible G(1) dependency.
The role of nutrient regulation and the Gpa2 protein in the mating pheromone response of C. albicans.
Secreted lipases of Candida albicans: cloning, characterisation and expression analysis of a new gene family with at least ten members.
Bcr1 functions downstream of Ssd1 to mediate antimicrobial peptide resistance in Candida albicans.
Candida albicans SSD1 can suppress multiple mutations in Saccharomyces cerevisiae.
SSD1 is integral to host defense peptide resistance in Candida albicans.
PMT family of Candida albicans: five protein mannosyltransferase isoforms affect growth, morphogenesis and antifungal resistance.
Virulence of the fungal pathogen Candida albicans requires the five isoforms of protein mannosyltransferases.
Metabolic specialization associated with phenotypic switching in Candidaalbicans.
RBR1, a novel pH-regulated cell wall gene of Candida albicans, is repressed by RIM101 and activated by NRG1.
Validation of Cdc68p as a novel antifungal target.
Candida albicans CHT3 encodes the functional homolog of the Cts1 chitinase of Saccharomyces cerevisiae.
Mass spectrometric analysis of the secretome of Candida albicans.
Micafungin alters the expression of genes related to cell wall integrity in Candida albicans biofilms.
Molecular cloning and characterization of chitinase genes from Candida albicans.
The Candida albicans CaACE2 gene affects morphogenesis, adherence and virulence.
A forkhead transcription factor is important for true hyphal as well as yeast morphogenesis in Candida albicans.
Proteolytic cleavage of covalently linked cell wall proteins by Candida albicans Sap9 and Sap10.
Functional characterization of myosin I tail regions in Candida albicans.
Myosin I is required for hypha formation in Candida albicans.
BAR domain proteins Rvs161 and Rvs167 contribute to Candida albicans endocytosis, morphogenesis, and virulence.
The Sur7 protein regulates plasma membrane organization and prevents intracellular cell wall growth in Candida albicans.
A core filamentation response network in Candida albicans is restricted to eight genes.
A genome-wide transcriptional analysis of morphology determination in Candida albicans.
Genome-wide analysis of Candida albicans gene expression patterns during infection of the mammalian kidney.
Genome-wide transcription profiling of the early phase of biofilm formation by Candida albicans.
Induction of the Candida albicans filamentous growth program by relief of transcriptional repression: a genome-wide analysis.
The moonlighting protein Tsa1p is implicated in oxidative stress response and in cell wall biogenesis in Candida albicans.
Transcriptional profiling in Candida albicans reveals new adaptive responses to extracellular pH and functions for Rim101p.
In Candida albicans, the Nim1 kinases Gin4 and Hsl1 negatively regulate pseudohypha formation and Gin4 also controls septin organization.
Rad52 depletion in Candida albicans triggers both the DNA-damage checkpoint and filamentation accompanied by but independent of expression of hypha-specific genes.
Regulation of Cdc42 GTPase activity in the formation of hyphae in Candida albicans.
SLA2 mutations cause SWE1-mediated cell cycle phenotypes in Candida albicans and Saccharomyces cerevisiae.
Phylogenetic relationships of fungal cytochromes c.
Activation of Rac1 by the guanine nucleotide exchange factor Dck1 is required for invasive filamentous growth in the pathogen Candida albicans.
Dominant negative selection of heterologous genes: isolation of Candida albicans genes that interfere with Saccharomyces cerevisiae mating factor-induced cell cycle arrest.
Evolution of a fungal regulatory gene family: the Zn(II)2Cys6 binuclear cluster DNA binding motif.
Expression of the Candida albicans morphogenesis regulator gene CZF1 and its regulation by Efg1p and Czf1p.
Filamentous growth of Candida albicans in response to physical environmental cues and its regulation by the unique CZF1 gene.
Functional importance of the DNA binding activity of Candida albicans Czf1p.
Invasive filamentous growth of Candida albicans is promoted by Czf1p-dependent relief of Efg1p-mediated repression.
Portrait of Candida albicans adherence regulators.
RNA sequencing revealed novel actors of the acquisition of drug resistance in Candida albicans.
The morphogenetic regulator Czf1p is a DNA-binding protein that regulates white opaque switching in Candida albicans.
A Candida albicans mannoprotein deprived of its mannan moiety is efficiently taken up and processed by human dendritic cells and induces T-cell activation without stimulating proinflammatory cytokine production.
Antigenic properties and processing requirements of 65-kilodalton mannoprotein, a major antigen target of anti-Candida human T-cell response, as disclosed by specific human T-cell clones.
Candida albicans Sun41p, a putative glycosidase, is involved in morphogenesis, cell wall biogenesis, and biofilm formation.
Differential release of an immunodominant 65 kDa mannoprotein antigen from yeast and mycelial forms of Candida albicans.
Effect of tunicamycin on Candida albicans biofilm formation and maintenance.
Generation of a recombinant 65-kilodalton mannoprotein, a major antigen target of cell-mediated immune response to Candida albicans.
Identification of a 65-kDa mannoprotein as a main target of human cell-mediated immune response to Candida albicans.
Identification of pH-regulated antigen 1 released from Candida albicans as the major ligand for leukocyte integrin alphaMbeta2.
Proteomic analysis of Candida albicans cell walls reveals covalently bound carbohydrate-active enzymes and adhesins.
Purification and biochemical characterization of a 65-kilodalton mannoprotein (MP65), a main target of anti-Candida cell-mediated immune responses in humans.
The 65 kDa mannoprotein gene of Candida albicans encodes a putative beta-glucanase adhesin required for hyphal morphogenesis and experimental pathogenicity.
Use of 65 kDa mannoprotein gene primers in Real Time PCR identification of Candida albicans in biological samples.
Identification of a new family of genes involved in beta-1,2-mannosylation of glycans in Pichia pastoris and Candida albicans.
Haploinsufficiency-based large-scale forward genetic analysis of filamentous growth in the diploid human fungal pathogen C.albicans.
Conserved functional domains of the RNA polymerase III general transcription factor BRF.
Candida albicans SH3-domain proteins involved in hyphal growth, cytokinesis, and vacuolar morphology.
Cdc28-Cln3 phosphorylation of Sla1 regulates actin patch dynamics in different modes of fungal growth.
Anchorage of Candida albicans Ssr1 to the cell wall, and transcript profiling of the null mutant.
Macromolecular crystal data phased by negative-stained electron-microscopy reconstructions.
N-acetylglucosamine-inducible CaGAP1 encodes a general amino acid permease which co-ordinates external nitrogen source response and morphogenesis in Candida albicans.
Nitrogen metabolism and virulence of Candida albicans require the GATA-type transcriptional activator encoded by GAT1.
Regulatory role of glycerol in Candida albicans biofilm formation.
CDK-dependent phosphorylation of Mob2 is essential for hyphal development in Candida albicans.
Conserved serine/threonine kinase encoded by CBK1 regulates expression of several hypha-associated transcripts and genes encoding cell wall proteins in Candida albicans.
Role of the RAM network in cell polarity and hyphal morphogenesis in Candida albicans.
The NDR/LATS kinase Cbk1 controls the activity of the transcriptional regulator Bcr1 during biofilm formation in Candida albicans.
A monoclonal antibody specific for Candida albicans Als4 demonstrates overlapping localization of Als family proteins on the fungal cell surface and highlights differences between Als localization in vitro and in vivo.
Candida albicans ALS1: domains related to a Saccharomyces cerevisiae sexual agglutinin separated by a repeating motif.
Candida albicans Als proteins mediate aggregation with bacteria and yeasts.
Candida albicans Als1p: an adhesin that is a downstream effector of the EFG1 filamentation pathway.
Candida albicans Sfl1 suppresses flocculation and filamentation.
Candida albicans Tpk1p and Tpk2p isoforms differentially regulate pseudohyphal development, biofilm structure, cell aggregation and adhesins expression.
Complementary adhesin function in C. albicans biofilm formation.
Contribution of Candida albicans ALS1 to the pathogenesis of experimental oropharyngeal candidiasis.
Degenerate peptide recognition by Candida albicans adhesins Als5p and Als1p.
Detection of Als proteins on the cell wall of Candida albicans in murine tissues.
Efg1 Controls caspofungin-induced cell aggregation of Candida albicans through the adhesin Als1.
Frequency and expression of ALS and HWP1 genotypes in Candida albicans strains isolated from Mexican patients suffering from vaginal candidosis.
Functional analysis of the Candida albicans ALS1 gene product.
Functional and structural diversity in the Als protein family of Candida albicans.
Functional control of the Candida albicans cell wall by catalytic protein kinase A subunit Tpk1.
Heterogeneous distribution of Candida albicans cell-surface antigens demonstrated with an Als1-specific monoclonal antibody.
In vivo inhibitory effect on the biofilm formation of Candida albicans by liverwort derived riccardin D.
Monitoring ALS1 and ALS3 gene expression during in vitro Candida albicans biofilm formation under continuous flow conditions.
Profiling of adhesive properties of the agglutinin-like sequence (ALS) protein family, a virulent attribute of Candida albicans.
Quantification of ALS1 gene expression in Candida albicans biofilms by RT-PCR using hybridisation probes on the LightCycler.
Real-time PCR expression profiling of genes encoding potential virulence factors in Candida albicans biofilms: identification of model-dependent and -independent gene expression.
Structure and function of glycosylated tandem repeats from Candida albicans Als adhesins.
The N-terminal part of Als1 protein from Candida albicans specifically binds fucose-containing glycans.
Use of green fluorescent protein and reverse transcription-PCR to monitor Candida albicans agglutinin-like sequence gene expression in a murine model of disseminated candidiasis.
Analysis of Candida albicans plasma membrane proteome.
The MARVEL domain protein Nce102 regulates actin organization and invasive growth of Candida albicans.
An analysis of the Candida albicans genome database for soluble secreted proteins using computer-based prediction algorithms.
Crystal structure of histone chaperone Vps75 from Candida albicans.
A single-copy suppressor of the Saccharomyces cerevisae late-mitotic mutants cdc15 and dbf2 is encoded by the Candida albicans CDC14 gene.
Sep7 is essential to modify septin ring dynamics and inhibit cell separation during Candida albicans hyphal growth.
The Cdc14p phosphatase affects late cell-cycle events and morphogenesis in Candida albicans.
Transcriptional analysis of the Candida albicans cell cycle.
Cyclin Cln3p links G1 progression to hyphal and pseudohyphal development in Candida albicans.
Molecular cloning and analysis of CDC28 and cyclin homologues from the human fungal pathogen Candida albicans.
Release from quorum-sensing molecules triggers hyphal formation during Candida albicans resumption of growth.
The F-box protein Grr1 regulates the stability of Ccn1, Cln3 and Hof1 and cell morphogenesis in Candida albicans.
The G1 cyclin Cln3 regulates morphogenesis in Candida albicans.
RIM101-dependent and -independent pathways govern pH responses in Candida albicans.
Ybp1 and Gpx3 signaling in Candida albicans govern hydrogen peroxide-induced oxidation of the Cap1 transcription factor and macrophage escape.
A family of Candida cell surface haem-binding proteins involved in haemin and haemoglobin-iron utilization.
Biofilm formation by Candida albicans mutants for genes coding fungal proteins exhibiting the eight-cysteine-containing CFEM domain.
Conserved and divergent roles of Bcr1 and CFEM proteins in Candida parapsilosis and Candida albicans.
Expression cloning of the Candida albicans CSA1 gene encoding a mycelial surface antigen by sorting of Saccharomyces cerevisiae transformants with monoclonal antibody-coated magnetic beads.
Identification of genes upregulated by the transcription factor Bcr1 that are involved in impermeability, impenetrability, and drug resistance of Candida albicans a/alpha biofilms.
Iron restriction-induced adaptations in the wall proteome of Candida albicans.
Oxygen accessibility and iron levels are critical factors for the antifungal action of ciclopirox against Candida albicans.
Some biological features of Candida albicans mutants for genes coding fungal proteins containing the CFEM domain.
Surface stress induces a conserved cell wall stress response in the pathogenic fungus Candida albicans.
Analysis of the interaction between the aspartic peptidase inhibitor SQAPI and aspartic peptidases using surface plasmon resonance.
Candida albicans hyphal formation and the expression of the Efg1-regulated proteinases Sap4 to Sap6 are required for the invasion of parenchymal organs.
Comprehensive characterization of secreted aspartic proteases encoded by a virulence gene family in Candida albicans.
Different isoforms of secreted aspartyl proteinases (Sap) are expressed by Candida albicans during oral and cutaneous candidosis in vivo.
Expression analysis of SIR2 and SAPs1-4 gene expression in Candida albicans treated with allicin compared to fluconazole.
In vitro study of secreted aspartyl proteinases Sap1 to Sap3 and Sap4 to Sap6 expression in Candida albicans pleomorphic forms.
Pathogen and host factors are needed to provoke a systemic host response to gastrointestinal infection of Drosophila larvae by Candida albicans.
Profile of Candida albicans-secreted aspartic proteinase elicited during vaginal infection.
Secreted aspartic peptidases of Candida albicans liberate bactericidal hemocidins from human hemoglobin.
Crystal structures of N-terminally truncated telomerase reverse transcriptase from fungi.
Crystal structures of N-terminally truncated telomerase reverse transcriptase from fungi‡.
Carbon source-induced reprogramming of the cell wall proteome and secretome modulates the adherence and drug resistance of the fungal pathogen Candida albicans.
Global transcriptional profiling of Candida albicans cwt1 null mutant.
Analysis of secreted aspartic proteinases from Candida albicans: purification and characterization of individual Sap1, Sap2 and Sap3 isoenzymes.
Candida albicans-secreted aspartic proteinases modify the epithelial cytokine response in an in vitro model of vaginal candidiasis.
Evidence that members of the secretory aspartyl proteinase gene family, in particular SAP2, are virulence factors for Candida vaginitis.
Host versus in vitro signals and intrastrain allelic differences in the expression of a Candida albicans virulence gene.
In vitro Candida albicans biofilm induced proteinase activity and SAP8 expression correlates with in vivo denture stomatitis severity.
Molecular cloning of the secretory acid proteinase gene from Candida albicans and its use as a species-specific probe.
The Inflammatory response induced by aspartic proteases of Candida albicans is independent of proteolytic activity.
The secreted aspartyl proteinases Sap1 and Sap2 cause tissue damage in an in vitro model of vaginal candidiasis based on reconstituted human vaginal epithelium.
The yeast Candida albicans evades human complement attack by secretion of aspartic proteases.
A GATA transcription factor recruits Hda1 in response to reduced Tor1 signaling to establish a hyphal chromatin state in Candida albicans.
Analysis of a fungus-specific transcription factor family, the Candida albicans zinc cluster proteins, by artificial activation.
Candida albicans Ume6, a filament-specific transcriptional regulator, directs hyphal growth via a pathway involving Hgc1 cyclin-related protein.
Candida albicans VMA3 is necessary for V-ATPase assembly and function and contributes to secretion and filamentation.
Candida albicans white and opaque cells undergo distinct programs of filamentous growth.
Dispersion as an important step in the Candida albicans biofilm developmental cycle.
Endosomal and AP-3-dependent vacuolar trafficking routes make additive contributions to Candida albicans hyphal growth and pathogenesis.
Expression levels of a filament-specific transcriptional regulator are sufficient to determine Candida albicans morphology and virulence.
Expression of UME6, a key regulator of Candida albicans hyphal development, enhances biofilm formation via Hgc1- and Sun41-dependent mechanisms.
The Yak1 kinase is involved in the initiation and maintenance of hyphal growth in Candida albicans.
UME6 is a crucial downstream target of other transcriptional regulators of true hyphal development in Candida albicans.
UME6, a novel filament-specific regulator of Candida albicans hyphal extension and virulence.
Deficiencies in the essential Smp3 mannosyltransferase block glycosylphosphatidylinositol assembly and lead to defects in growth and cell wall biogenesis in Candida albicans.
SST2, a regulator of G-protein signaling for the Candida albicans mating response pathway.
A relay network of extracellular heme-binding proteins drives C. albicans iron acquisition from hemoglobin.
An eight-cysteine-containing CFEM domain unique to a group of fungal membrane proteins.
Genome-wide expression profiling of the response to ciclopirox olamine in Candida albicans.
Regulation of the hypoxic response in Candida albicans.
Structural basis of haem-iron acquisition by fungal pathogens.
The Candida albicans ERG26 gene encoding the C-3 sterol dehydrogenase (C-4 decarboxylase) is essential for growth.
A Candida albicans homolog of CDC25 is functional in Saccharomyces cerevisiae.
A proteomic analysis of the salt, cadmium and peroxide stress responses in Candida albicans and the role of the Hog1 stress-activated MAPK in regulating the stress-induced proteome.
Evolutionary tinkering with conserved components of a transcriptional regulatory network.
G1/S transcription factor orthologues Swi4p and Swi6p are important but not essential for cell proliferation and influence hyphal development in the fungal pathogen Candida albicans.
Transcription factor substitution during the evolution of fungal ribosome regulation.
Cloning of the Candida albicans nucleoside transporter by complementation of nucleoside transport-deficient Saccharomyces.
Phosphatidylserine synthase and phosphatidylserine decarboxylase are essential for cell wall integrity and virulence in Candida albicans.
Conservation and evolution of cis-regulatory systems in ascomycete fungi.
Characterization of thiol-specific antioxidant 1 (TSA1) of Candida albicans.
Identification of cell surface determinants in Candida albicans reveals Tsa1p, a protein differentially localized in the cell.
2-dodecanol (decyl methyl carbinol) inhibits hyphal formation and SIR2 expression in C. albicans.
Candida albicans, a distinctive fungal model for cellular aging study.
Inhibition of hyphae formation and SIR2 expression in Candida albicans treated with fresh Allium sativum (garlic) extract.
N-acetylglucosamine kinase, HXK1 is involved in morphogenetic transition and metabolic gene expression in Candida albicans.
Phenotypic switching in Candida albicans is controlled by a SIR2 gene.
Candidalysin is a fungal peptide toxin critical for mucosal infection.
Candidalysins Are a New Family of Cytolytic Fungal Peptide Toxins.
Cloning and characterization of ECE1, a gene expressed in association with cell elongation of the dimorphic pathogen Candida albicans.
Human serum inhibits adhesion and biofilm formation in Candida albicans.
Crystal structure of glutamate dehydrogenase 3 from Candida albicans.
A proteomic analysis of secretory proteins of a pre-vacuolar mutant of Candida albicans.
EFG1 is a major regulator of cell wall dynamics in Candida albicans as revealed by DNA microarrays.
Genes selectively up-regulated by pheromone in white cells are involved in biofilm formation in Candida albicans.
Requirement for Candida albicans Sun41 in biofilm formation and virulence.
SUN proteins belong to a novel family of beta-(1,3)-glucan-modifying enzymes involved in fungal morphogenesis.
The SUN41 and SUN42 genes are essential for cell separation in Candida albicans.
Transcriptional response of Candida albicans to hypoxia: linkage of oxygen sensing and Efg1p-regulatory networks.
Characterization of human, Schizosaccharomyces pombe, and Candida albicans mRNA cap methyltransferases and complete replacement of the yeast capping apparatus by mammalian enzymes.
Neddylation and CAND1 independently stimulate SCF ubiquitin ligase activity in Candida albicans.
ALS3 and ALS8 represent a single locus that encodes a Candida albicans adhesin; functional comparisons between Als3p and Als1p.
Evaluation of the role of Candida albicans agglutinin-like sequence (Als) proteins in human oral epithelial cell interactions.
In vitro and in vivo activities of pterostilbene against Candida albicans biofilms.
Investigation of the function of Candida albicans Als3 by heterologous expression in Candida glabrata.
Lipopeptides from Bacillus strain AR2 inhibits biofilm formation by Candida albicans.
O-mannosylation in Candida albicans enables development of interkingdom biofilm communities.
Participation of Candida albicans transcription factor RLM1 in cell wall biogenesis and virulence.
Quantifying the forces driving cell-cell adhesion in a fungal pathogen.
Recognition of Candida albicans Als3 by the germ tube-specific monoclonal antibody 3D9.3.
The peptide-binding cavity is essential for Als3-mediated adhesion of Candida albicans to human cells.
Therapeutic Potential of Thiazolidinedione-8 as an Antibiofilm Agent against Candida albicans.
The Candida albicans 14-3-3 gene, BMH1, is essential for growth.
Identification of the putative protein phosphatase gene PTC1 as a virulence-related gene using a silkworm model of Candida albicans infection.
Ppg1, a PP2A-type protein phosphatase, controls filament extension and virulence in Candida albicans.
Systematic screens of a Candida albicans homozygous deletion library decouple morphogenetic switching and pathogenicity.
Thiamin pyrimidine biosynthesis in Candida albicans: a remarkable reaction between histidine and pyridoxal phosphate.
Large-scale identification of putative exported proteins in Candida albicans by genetic selection.
The presence of disulfide bonds reveals an evolutionarily conserved mechanism involved in mitochondrial protein translocase assembly.
Candida albicans Cas5, a regulator of cell wall integrity, is required for virulence in murine and toll mutant fly models.
Candida albicans hyphal formation and virulence assessed using a Caenorhabditis elegans infection model.
Isolation, characterization, and regulation of the Candida albicans ERG27 gene encoding the sterol 3-keto reductase.
Eukaryotic resistance to fluoride toxicity mediated by a widespread family of fluoride export proteins.
Cloning and sequencing of the Candida albicans homologue of SRB1/PSA1/VIG9, the essential gene encoding GDP-mannose pyrophosphorylase in Saccharomyces cerevisiae.
The VIG9 gene products from the human pathogenic fungi Candida albicans and Candida glabrata encode GDP-mannose pyrophosphorylase.
Diverged binding specificity of Rim101p, the Candida albicans ortholog of PacC.
Transcription profiling of cyclic AMP signaling in Candida albicans.
Crk1, a novel Cdc2-related protein kinase, is required for hyphal development and virulence in Candida albicans.
The mannan of Candida albicans lacking beta-1,2-linked oligomannosides increases the production of inflammatory cytokines by dendritic cells.
Identification and cloning of GCA1, a gene that encodes a cell surface glucoamylase from Candida albicans.
Forward genetics in Candida albicans that reveals the Arp2/3 complex is required for hyphal formation, but not endocytosis.
Allelic variation in the contiguous loci encoding Candida albicans ALS5, ALS1 and ALS9.
Structural basis for the broad specificity to host-cell ligands by the pathogenic fungus Candida albicans.
Unequal contribution of ALS9 alleles to adhesion between Candida albicans and human vascular endothelial cells.
Cell surface changes in the Candida albicans mitochondrial mutant goa1Delta are associated with reduced recognition by innate immune cells.
Disruption of Candida albicans IFF4 gene involves modifications of the cell electrical surface properties.
Gene overexpression/suppression analysis of candidate virulence factors of Candida albicans.
Identification and characterization of a sphingolipid delta 4-desaturase family.
Seryl-tRNA synthetase is not responsible for the evolution of CUG codon reassignment in Candida albicans.
A transcription factor regulatory cascade controls secreted aspartic protease expression in Candida albicans.
Control of ammonium permease expression and filamentous growth by the GATA transcription factors GLN3 and GAT1 in Candida albicans.
Dur3 is the major urea transporter in Candida albicans and is co-regulated with the urea amidolyase Dur1,2.
GLN3 encodes a global regulator of nitrogen metabolism and virulence of C. albicans.
Rhb1 regulates the expression of secreted aspartic protease 2 through the TOR signaling pathway in Candida albicans.
Inhibition of inositol phosphorylceramide synthase by the cyclic peptide aureobasidin A.
Medicinal genetics approach towards identifying the molecular target of a novel inhibitor of fungal cell wall assembly.
Cloning and expression of the gene from Candida albicans that encodes a high-affinity corticosteroid-binding protein.
Candida albicans SRR1, a putative two component response regulator gene, is required for stress adaptation, morphogenesis and virulence.
A screen in Saccharomyces cerevisiae identified CaMCM1, an essential gene in Candida albicans crucial for morphogenesis.
The histone deacetylase genes HDA1 and RPD3 play distinct roles in regulation of high-frequency phenotypic switching in Candida albicans.
The zinc cluster transcription factor Ahr1p directs Mcm1p regulation of Candida albicans adhesion.
Global transcriptome sequencing identifies chlamydospore specific markers in Candida albicans and Candida dubliniensis.
Arv1 lipid transporter function is conserved between pathogenic and nonpathogenic fungi.
Candida albicans transcription factor Ace2 regulates metabolism and is required for filamentation in hypoxic conditions.
Characterization of the CaENG1 gene encoding an endo-1,3-beta-glucanase involved in cell separation in Candida albicans.
The serine/threonine protein phosphatase SIT4 modulates yeast-to-hypha morphogenesis and virulence in Candida albicans.
A DNA-binding protein from Candida albicans that binds to the RPG box of Saccharomyces cerevisiae and the telomeric repeat sequence of C. albicans.
Biochemical and genetic characterization of Rbf1p, a putative transcription factor of Candida albicans.
Identification of Candida albicans genes induced during thrush offers insight into pathogenesis.
The Sko1 protein represses the yeast-to-hypha transition and regulates the oxidative stress response in Candida albicans.
Transcriptional profiling of the Candida albicans Ssk1p receiver domain point mutants and their virulence.
Identification of a putative DEAD-box RNA helicase and a zinc-finger protein in Candida albicans by functional complementation of the S. cerevisiae rok1 mutation.
Alternative mating type configurations (a/alpha versus a/a or alpha/alpha) of Candida albicans result in alternative biofilms regulated by different pathways.
Candida albicans Hyr1p confers resistance to neutrophil killing and is a potential vaccine target.
Candida albicans biofilm formation in a new in vivo rat model.
Candida albicans forms biofilms on the vaginal mucosa.
Development and validation of an in vivo Candida albicans biofilm denture model.
Estrogen promotes innate immune evasion of Candida albicans through inactivation of the alternative complement system.
Hyphal induction in the human fungal pathogen Candida albicans reveals a characteristic wall protein profile.
Identification of potential cell-surface proteins in Candida albicans and investigation of the role of a putative cell-surface glycosidase in adhesion and virulence.
The CRH family coding for cell wall glycosylphosphatidylinositol proteins with a predicted transglycosidase domain affects cell wall organization and virulence of Candida albicans.
The P-type ATPase Spf1 is required for endoplasmic reticulum functions and cell wall integrity in Candida albicans.
CDK regulates septin organization through cell-cycle-dependent phosphorylation of the Nim1-related kinase Gin4.
Comparison of INO1 gene sequences and products in Candida albicans and Saccharomyces cerevisiae.
Identification of a mating type-like locus in the asexual pathogenic yeast Candida albicans.
Mds3 regulates morphogenesis in Candida albicans through the TOR pathway.
Complete glycosylphosphatidylinositol anchors are required in Candida albicans for full morphogenesis, virulence and resistance to macrophages.
GPI7 affects cell-wall protein anchorage in Saccharomyces cerevisiae and Candida albicans.
A putative dual-specific protein phosphatase encoded by YVH1 controls growth, filamentation and virulence in Candida albicans.
Hgc1 mediates dynamic Candida albicans-endothelium adhesion events during circulation.
Hgc1, a novel hypha-specific G1 cyclin-related protein regulates Candida albicans hyphal morphogenesis.
Hyphal chain formation in Candida albicans: Cdc28-Hgc1 phosphorylation of Efg1 represses cell separation genes.
Hyphal growth in Candida albicans requires the phosphorylation of Sec2 by the Cdc28-Ccn1/Hgc1 kinase.
Phosphorylation of Rga2, a Cdc42 GAP, by CDK/Hgc1 is crucial for Candida albicans hyphal growth.
Tcc1p, a novel protein containing the tetratricopeptide repeat motif, interacts with Tup1p to regulate morphological transition and virulence in Candida albicans.
Temporal and spatial control of HGC1 expression results in Hgc1 localization to the apical cells of hyphae in Candida albicans.
Atg8 and Ire1 in combination regulate the autophagy-related endoplasmic reticulum stress response in Candida albicans.
Stress-associated endoplasmic reticulum protein 1 (SERP1) and Atg8 synergistically regulate unfolded protein response (UPR) that is independent on autophagy in Candida albicans.
The malfunction of peroxisome has an impact on the oxidative stress sensitivity in Candida albicans.
Cellular and molecular biology of Candida albicans estrogen response.
Global analysis of altered gene expression during morphogenesis of Candida albicans in vitro.
Regulation of copper toxicity by Candida albicans GPA2.
The CaCTR1 gene is required for high-affinity iron uptake and is transcriptionally controlled by a copper-sensing transactivator encoded by CaMAC1.
The Candida albicans CTR1 gene encodes a functional copper transporter.
SKN7 of Candida albicans: mutant construction and phenotype analysis.
Characterizing the role of cell-wall beta-1,3-exoglucanase Xog1p in Candida albicans adhesion by the human antimicrobial peptide LL-37.
Isolation and characterization of the GFA1 gene encoding the glutamine:fructose-6-phosphate amidotransferase of Candida albicans.
The crystal and solution studies of glucosamine-6-phosphate synthase from Candida albicans.
Cloning and nucleotide sequence analysis of the Candida albicans enolase gene.
Molecular cloning and characterization of the Candida albicans enolase gene.
Molecular cloning of cDNA and analysis of protein secondary structure of Candida albicans enolase, an abundant, immunodominant glycolytic enzyme.
An RNA transport system in Candida albicans regulates hyphal morphology and invasive growth.
Morphogenesis, adhesive properties, and antifungal resistance depend on the Pmt6 protein mannosyltransferase in the fungal pathogen candida albicans.
Analysis of the Candida albicans Als2p and Als4p adhesins suggests the potential for compensatory function within the Als family.
Temporal analysis of Candida albicans gene expression during biofilm development.
An Ashbya gossypii cts2 mutant deficient in a sporulation-specific chitinase can be complemented by Candida albicans CHT4.
Low virulent strains of Candida albicans: unravelling the antigens for a future vaccine.
Elucidation of potentially virulent factors of Candida albicans during serum adaptation by using quantitative time-course proteomics.
Evolution of pathogenicity and sexual reproduction in eight Candida genomes.
CaMac1, a Candida albicans copper ion-sensing transcription factor, promotes filamentous and invasive growth in Saccharomyces cerevisiae.
From experimental setup to data analysis in transcriptomics: copper metabolism in the human pathogen Candida albicans.
Microbial interactions and differential protein expression in Staphylococcus aureus -Candida albicans dual-species biofilms.
Identification and characterization of a previously undescribed family of sequence-specific DNA-binding domains.
Structure of the transcriptional network controlling white-opaque switching in Candida albicans.
Molecular and phenotypic analysis of CaVRG4, encoding an essential Golgi apparatus GDP-mannose transporter.
Candida albicans hyphae have a Spitzenkorper that is distinct from the polarisome found in yeast and pseudohyphae.
Ras1-induced hyphal development in Candida albicans requires the formin Bni1.
Role of actin cytoskeletal dynamics in activation of the cyclic AMP pathway and HWP1 gene expression in Candida albicans.
The formin family protein CaBni1p has a role in cell polarity control during both yeast and hyphal growth in Candida albicans.
Yeast-to-hyphal transition triggers formin-dependent Golgi localization to the growing tip in Candida albicans.
Sequence analysis and expression of the two genes for elongation factor 1 alpha from the dimorphic yeast Candida albicans.
Candida albicans RFX2 encodes a DNA binding protein involved in DNA damage responses, morphogenesis, and virulence.
NRG1 represses yeast-hypha morphogenesis and hypha-specific gene expression in Candida albicans.
The transcriptomes of two heritable cell types illuminate the circuit governing their differentiation.
Transcriptional responses of candida albicans to epithelial and endothelial cells.
Candida albicans Rim13p, a protease required for Rim101p processing at acidic and alkaline pHs.
Candida albicans Hgt1p, a multifunctional evasion molecule: complement inhibitor, CR3 analogue, and human immunodeficiency virus-binding molecule.
Identification and phylogenetic analysis of a glucose transporter gene family from the human pathogenic yeast Candida albicans.
Molecular cloning and functional characterisation of a glucose transporter, CaHGT1, of Candida albicans.
PIF-pocket as a target for C. albicans Pkh selective inhibitors.
Carbonic anhydrase activators: activation of the beta-carbonic anhydrases from the pathogenic fungi Candida albicans and Cryptococcus neoformans with amines and amino acids.
Carbonic anhydrase inhibitors. Inhibition and homology modeling studies of the fungal beta-carbonic anhydrase from Candida albicans with sulfonamides.
Carbonic anhydrase inhibitors. Inhibition of the beta-class enzymes from the fungal pathogens Candida albicans and Cryptococcus neoformans with aliphatic and aromatic carboxylates.
Carbonic anhydrase inhibitors. Inhibition of the fungal beta-carbonic anhydrases from Candida albicans and Cryptococcus neoformans with boronic acids.
Carbonic anhydrase inhibitors. The beta-carbonic anhydrases from the fungal pathogens Cryptococcus neoformans and Candida albicans are strongly inhibited by substituted-phenyl-1H-indole-5-sulfonamides.
Carbonic anhydrase inhibitors: inhibition of the beta-class enzymes from the fungal pathogens Candida albicans and Cryptococcus neoformans with simple anions.
Dithiocarbamates are strong inhibitors of the beta-class fungal carbonic anhydrases from Cryptococcus neoformans, Candida albicans and Candida glabrata.
Fungal adenylyl cyclase integrates CO2 sensing with cAMP signaling and virulence.
Natural product-based phenols as novel probes for mycobacterial and fungal carbonic anhydrases.
The bZIP transcription factor Rca1p is a central regulator of a novel CO(2) sensing pathway in yeast.
Dominant active alleles of RIM101 (PRR2) bypass the pH restriction on filamentation of Candida albicans.
Effect of environmental pH on morphological development of Candida albicans is mediated via the PacC-related transcription factor encoded by PRR2.
Structural analyses of PCNA from the fungal pathogen Candida albicans identify three regions with species-specific conformations.
A multifunctional, synthetic Gaussia princeps luciferase reporter for live imaging of Candida albicans infections.
The GPI-modified proteins Pga59 and Pga62 of Candida albicans are required for cell wall integrity.
A proteomic view of Candida albicans yeast cell metabolism in exponential and stationary growth phases.
Proteomic analysis of the oxidative stress response in Candida albicans.
Clathrin- and Arp2/3-independent endocytosis in the fungal pthogen Candida albicans.
Cloning and characterization of the 2,3-oxidosqualene cyclase-coding gene of Candida albicans.
Ergosterol gene expression in wild-type and ergosterol-deficient mutants of Candida albicans.
Sequence of the Candida albicans erg7 gene.
Biogenesis of Candida albicans Can1 permease expressed in Saccharomyces cerevisiae.
Degradation of Candida albicans Can1 permease expressed in Saccharomyces cerevisiae.
Transport properties of a C. albicans amino-acid permease whose putative gene was cloned and expressed in S. cerevisiae.
APSES proteins regulate morphogenesis and metabolism in Candida albicans.
BDSF inhibits Candida albicans adherence to urinary catheters.
Increased filamentous growth of Candida albicans in simulated microgravity.
Insight into the antiadhesive effect of yeast wall protein 1 of Candida albicans.
Yeast wall protein 1 of Candida albicans.
Zap1 control of cell-cell signaling in Candida albicans biofilms.
Candida albicans cell surface superoxide dismutases degrade host-derived reactive oxygen species to escape innate immune surveillance.
Superoxide dismutases in Candida albicans: transcriptional regulation and functional characterization of the hyphal-induced SOD5 gene.
Monosomy of a specific chromosome determines L-sorbose utilization: a novel regulatory mechanism in Candida albicans.
Cloning, sequencing, expression and allelic sequence diversity of ERG3 (C-5 sterol desaturase gene) in Candida albicans.
Identification and characterization of four azole-resistant erg3 mutants of Candida albicans.
Resistance to fluconazole and cross-resistance to amphotericin B in Candida albicans from AIDS patients caused by defective sterol delta5,6-desaturation.
Deletion of the CaBIG1 gene reduces beta-1,6-glucan synthesis, filamentation, adhesion, and virulence in Candida albicans.
Role of the Candida albicans MNN1 gene family in cell wall structure and virulence.
The histidine kinases of Candida albicans: regulation of cell wall mannan biosynthesis.
Candida albicans Csy1p is a nutrient sensor important for activation of amino acid uptake and hyphal morphogenesis.
Cap1p is involved in multiple pathways of oxidative stress response in Candida albicans.
Dbf2 is essential for cytokinesis and correct mitotic spindle formation in Candida albicans.
Candida albicans MTLalpha tup1Delta mutants can reversibly switch to mating-competent, filamentous growth forms.
Cloning and regulated expression of the Candida albicans phospholipase B (PLB1) gene.
Control of filament formation in Candida albicans by the transcriptional repressor TUP1.
Role of hyphal formation in interactions of Candida albicans with endothelial cells.
Roles of TUP1 in switching, phase maintenance, and phase-specific gene expression in Candida albicans.
cDNA microarray analysis of differential gene expression in Candida albicans biofilm exposed to farnesol.
Analysis of the serologic response to systemic Candida albicans infection in a murine model.
Identification of Candida albicans antigens reactive with immunoglobulin E antibody of human sera.
Characterisation of D-arabinono-1,4-lactone oxidase from Candida albicans ATCC 10231.
Deficiency of D-erythroascorbic acid attenuates hyphal growth and virulence of Candida albicans.
Isolation and sequence of the t-RNA ligase-encoding gene of Candida albicans.
Candida albicans Msi3p, a homolog of the Saccharomyces cerevisiae Sse1p of the Hsp70 family, is involved in cell growth and fluconazole tolerance.
Serological profiling of a Candida albicans protein microarray reveals permanent host-pathogen interplay and stage-specific responses during candidemia.
The Candida albicans plasma membrane protein Rch1p, a member of the vertebrate SLC10 carrier family, is a novel regulator of cytosolic Ca2+ homoeostasis.
Shp1, a regulator of protein phosphatase 1 Glc7, has important roles in cell morphogenesis, cell cycle progression and DNA damage response in Candida albicans.
Spindle assembly checkpoint component CaMad2p is indispensable for Candida albicans survival and virulence in mice.
The essentiality of the fungus-specific Dam1 complex is correlated with a one-kinetochore-one-microtubule interaction present throughout the cell cycle, independent of the nature of a centromere.
A versatile overexpression strategy in the pathogenic yeast Candida albicans: identification of regulators of morphogenesis and fitness.
Candida albicans Sfl2, a temperature-induced transcriptional regulator, is required for virulence in a murine gastrointestinal infection model.
Roles of Candida albicans Sfl1 in hyphal development.
The quorum-sensing molecules farnesol/homoserine lactone and dodecanol operate via distinct modes of action in Candida albicans.
Cloning and functional study of CaPPe1 in Candida albicans by using Saccharomyces cerevisiae model system.
The contribution of Candida albicans vacuolar ATPase subunit V1B encoded by VMA2 to stress response, autophagy, and virulence is independent of environmental pH.
Isolation and sequencing of the Candida albicans MSI3, a putative novel member of the HSP70 family.
PRR1, a homolog of Aspergillus nidulans palF, controls pH-dependent gene expression and filamentation in Candida albicans.
Molecular analysis of the Candida albicans homolog of Saccharomyces cerevisiae MNN9, required for glycosylation of cell wall mannoproteins.
Isolation of a Candida albicans gene, tightly linked to URA3, coding for a putative transcription factor that suppresses a Saccharomyces cerevisiae aft1 mutation.
Mutation in IRO1 tightly linked with URA3 gene reduces virulence of Candida albicans.
Evolution of a combinatorial transcriptional circuit: a case study in yeasts.
Characterization, heterologous expression and functional analysis of mevalonate diphosphate decarboxylase gene (MVD) of Candida albicans.
Roles of Candida albicans Dfg5p and Dcw1p cell surface proteins in growth and hypha formation.
Csa2, a member of the Rbt5 protein family, is involved in the utilization of iron from human hemoglobin during Candida albicans hyphal growth.
Establishment and evaluation of a double antibody sandwich ELISA to detect Csa2 protein of Candida albicans.
Overcoming Fungal Echinocandin Resistance through Inhibition of the Non-essential Stress Kinase Yck2.
Evaluation of the roles of four Candida albicans genes in virulence by using gene disruption strains that express URA3 from the native locus.
A Candida albicans petite mutant strain with uncoupled oxidative phosphorylation overexpresses MDR1 and has diminished susceptibility to fluconazole and voriconazole.
A key structural domain of the Candida albicans Mdr1 protein.
Analysis of a Candida albicans gene that encodes a novel mechanism for resistance to benomyl and methotrexate.
Candida albicans gene encoding resistance to benomyl and methotrexate is a multidrug resistance gene.
Deciphering azole resistance mechanisms with a focus on transcription factor-encoding genes TAC1, MRR1 and UPC2 in a set of fluconazole-resistant clinical isolates of Candida albicans.
Differential requirement of the transcription factor Mcm1 for activation of the Candida albicans multidrug efflux pump MDR1 by its regulators Mrr1 and Cap1.
Distinct patterns of gene expression associated with development of fluconazole resistance in serial candida albicans isolates from human immunodeficiency virus-infected patients with oropharyngeal candidiasis.
Drug resistance genes and trailing growth in Candida albicans isolates.
Drug-induced regulation of the MDR1 promoter in Candida albicans.
Fluconazole transport into Candida albicans secretory vesicles by the membrane proteins Cdr1p, Cdr2p, and Mdr1p.
Functional dissection of a Candida albicans zinc cluster transcription factor, the multidrug resistance regulator Mrr1.
Genomewide location analysis of Candida albicans Upc2p, a regulator of sterol metabolism and azole drug resistance.
Identification of promoter elements responsible for the regulation of MDR1 from Candida albicans, a major facilitator transporter involved in azole resistance.
Increased mRNA levels of ERG16, CDR, and MDR1 correlate with increases in azole resistance in Candida albicans isolates from a patient infected with human immunodeficiency virus.
Inducible and constitutive activation of two polymorphic promoter alleles of the Candida albicans multidrug efflux pump MDR1.
Inhibition of Candida albicans virulence factors by novel levofloxacin derivatives.
Multidrug resistance in Candida albicans: disruption of the BENr gene.
Multidrug-resistant transport proteins in yeast: complete inventory and phylogenetic characterization of yeast open reading frames with the major facilitator superfamily.
Multiple cis-acting sequences mediate upregulation of the MDR1 efflux pump in a fluconazole-resistant clinical Candida albicans isolate.
Overexpression of the MDR1 gene is sufficient to confer increased resistance to toxic compounds in Candida albicans.
Proteomic analysis of Mrr1p- and Tac1p-associated differential protein expression in azole-resistant clinical isolates of Candida albicans.
Rapid, transient fluconazole resistance in Candida albicans is associated with increased mRNA levels of CDR.
Regulation of efflux pump expression and drug resistance by the transcription factors Mrr1, Upc2, and Cap1 in Candida albicans.
Rep1p negatively regulating MDR1 efflux pump involved in drug resistance in Candida albicans.
Rifampicin induces MDR1 expression in Candida albicans.
SAGA/ADA complex subunit Ada2 is required for Cap1- but not Mrr1-mediated upregulation of the Candida albicans multidrug efflux pump MDR1.
Specificity of drug transport mediated by CaMDR1: a major facilitator of Candida albicans.
Susceptibilities of Candida albicans multidrug transporter mutants to various antifungal agents and other metabolic inhibitors.
Targeted gene disruption in Candida albicans wild-type strains: the role of the MDR1 gene in fluconazole resistance of clinical Candida albicans isolates.
The bZip transcription factor Cap1p is involved in multidrug resistance and oxidative stress response in Candida albicans.
The transcription factor Mrr1p controls expression of the MDR1 efflux pump and mediates multidrug resistance in Candida albicans.
Transcriptional regulation of MDR1, encoding a drug efflux determinant, in fluconazole-resistant Candida albicans strains through an Mcm1p binding site.
Glycolytic enzymes of Candida albicans are nonubiquitous immunogens during candidiasis.
Crystal structure of Gig2 protein from Candida albicans provides a structural insight into DUF1479 family oxygenases.
Candida albicans SOD5 represents the prototype of an unprecedented class of Cu-only superoxide dismutases required for pathogen defense.
Granulocytes govern the transcriptional response, morphology and proliferation of Candida albicans in human blood.
Inhibitory effect of Shikonin on Candida albicans growth.
Superoxide dismutases are involved in Candida albicans biofilm persistence against miconazole.
Design, synthesis, inhibition studies, and molecular modeling of pepstatin analogues addressing different secreted aspartic proteinases of Candida albicans.
Multiplicity of genes encoding secreted aspartic proteinases in Candida species.
Genome-wide expression profiling of the response to terbinafine in Candida albicans using a cDNA microarray analysis.
Structure and regulation of the HSP90 gene from the pathogenic fungus Candida albicans.
A histone deacetylation inhibitor and mutant promote colony-type switching of the human pathogen Candida albicans.
Adaptation of the Efg1p morphogenetic pathway in Candida albicans by negative autoregulation and PKA-dependent repression of the EFG1 gene.
HOS2 and HDA1 encode histone deacetylases with opposing roles in Candida albicans morphogenesis.
Hyphal development in Candida albicans requires two temporally linked changes in promoter chromatin for initiation and maintenance.
Lysine deacetylases Hda1 and Rpd3 regulate Hsp90 function thereby governing fungal drug resistance.
Sch9 kinase integrates hypoxia and CO2 sensing to suppress hyphal morphogenesis in Candida albicans.
Cloning, purification, and properties of Candida albicans thymidylate synthase.
The Candida albicans cell wall protein Rhd3/Pga29 is abundant in the yeast form and contributes to virulence.
The cell wall protein Rhd3/Pga29 is over-expressed in Candida albicans upon micafungin treatment.
AP1-mediated multidrug resistance in Saccharomyces cerevisiae requires FLR1 encoding a transporter of the major facilitator superfamily.
Analysis of the oxidative stress regulation of the Candida albicans transcription factor, Cap1p.
Baicalein induces programmed cell death in Candida albicans.
Cap1p attenuates the apoptosis of Candida albicans.
Cap1p plays regulation roles in redox, energy metabolism and substance transport: an investigation on Candida albicans under normal culture condition.
Exposure to caspofungin activates Cap and Hog pathways in Candida albicans.
Expression of Candida albicans glutathione transferases is induced inside phagocytes and upon diverse environmental stresses.
Genome-wide mapping of the coactivator Ada2p yields insight into the functional roles of SAGA/ADA complex in Candida albicans.
Glucose promotes stress resistance in the fungal pathogen Candida albicans.
Identification and characterization of Cor33p, a novel protein implicated in tolerance towards oxidative stress in Candida albicans.
Mechanisms underlying the exquisite sensitivity of Candida albicans to combinatorial cationic and oxidative stress that enhances the potent fungicidal activity of phagocytes.
Stress-induced gene expression in Candida albicans: absence of a general stress response.
The Hog1 MAP kinase controls respiratory metabolism in the fungal pathogen Candida albicans.
The role of Candida albicans AP-1 protein against host derived ROS in in vivo models of infection.
Thioredoxin regulates multiple hydrogen peroxide-induced signaling pathways in Candida albicans.
Trehalose is an important mediator of Cap1p oxidative stress response in Candida albicans.
Molecular cloning of a gene encoding translation initiation factor (TIF) from Candida albicans.
Copper-dependent transcriptional regulation by Candida albicans Mac1p.
Glycosylphosphatidylinositol-anchored proteases of Candida albicans target proteins necessary for both cellular processes and host-pathogen interactions.
Functional analysis of Candida albicans genes encoding SH3-domain-containing proteins.
Avirulence of Candida albicans CaHK1 mutants in a murine model of hematogenously disseminated candidiasis.
Deletion of the Candida albicans histidine kinase gene CHK1 improves recognition by phagocytes through an increased exposure of cell wall beta-1,3-glucans.
Deletion of the two-component histidine kinase gene (CHK1) of Candida albicans contributes to enhanced growth inhibition and killing by human neutrophils in vitro.
Effects of histidine kinase gene CHK1 on some biological characteristics of Candida albicans.
Flocculation of hyphae is associated with a deletion in the putative CaHK1 two-component histidine kinase gene from Candida albicans.
Identification of a putative histidine kinase two-component phosphorelay gene (CaHK1) in Candida albicans.
Roles of three histidine kinase genes in hyphal development and virulence of the pathogenic fungus Candida albicans.
Studies on the regulation of the two-component histidine kinase gene CHK1 in Candida albicans using the heterologous lacZ reporter gene.
Temporal expression of the Candida albicans genes CHK1 and CSSK1, adherence, and morphogenesis in a model of reconstituted human esophageal epithelial candidiasis.
The Candida albicans histidine kinase Chk1p: signaling and cell wall mannan.
The Ssk1p response regulator and Chk1p histidine kinase mutants of Candida albicans are hypersensitive to fluconazole and voriconazole.
The role of the Candida albicans histidine kinase (CHK1) gene in the regulation of cell wall mannan and glucan biosynthesis.
The two-component signal transduction protein Chk1p regulates quorum sensing in Candida albicans.
Cloning and functional expression of UGT genes encoding sterol glucosyltransferases from Saccharomyces cerevisiae, Candida albicans, Pichia pastoris, and Dictyostelium discoideum.
Candida albicans SUR7 contributes to secretion, biofilm formation, and macrophage killing.
Sur7 promotes plasma membrane organization and is needed for resistance to stressful conditions and to the invasive growth and virulence of Candida albicans.
The Candida albicans Sur7 protein is needed for proper synthesis of the fibrillar component of the cell wall that confers strength.
Disruption of the Candida albicans TPS1 gene encoding trehalose-6-phosphate synthase impairs formation of hyphae and decreases infectivity.
Structural and In Vivo Studies on Trehalose-6-Phosphate Synthase from Pathogenic Fungi Provide Insights into Its Catalytic Mechanism, Biological Necessity, and Potential for Novel Antifungal Drug Design.
Membrane sphingolipid-ergosterol interactions are important determinants of multidrug resistance in Candida albicans.
Purification and characterization of a catechol 1,2-dioxygenase from a phenol degrading Candida albicans TL3.
A Candida albicans gene encoding a DNA ligase.
An evaluation of the role of LIG4 in genomic instability and adaptive mutagenesis in Candida albicans.
Cell cycle regulation of a DNA ligase-encoding gene (CaLIG4) from Candida albicans.
Phenotypic analysis and virulence of Candida albicans LIG4 mutants.
Global gene deletion analysis exploring yeast filamentous growth.
Analysis of heterologous expression of Candida albicans SEC61 gene reveals differences in Sec61p homologues related to species-specific functionality.
The TATA-binding protein (TBP) from the human fungal pathogen Candida albicans can complement defects in human and yeast TBPs.
Spitzenkorper, exocyst, and polarisome components in Candida albicans hyphae show different patterns of localization and have distinct dynamic properties.
A Candida biofilm-induced pathway for matrix glucan delivery: implications for drug resistance.
An exo-beta-(1,3)-glucanase of Candida albicans: purification of the enzyme and molecular cloning of the gene.
Carbohydrate binding sites in Candida albicans exo-beta-1,3-glucanase and the role of the Phe-Phe 'clamp' at the active site entrance.
Hydrolase and transferase activities of the beta-1,3-exoglucanase of Candida albicans.
Identification of Glu-330 as the catalytic nucleophile of Candida albicans exo-beta-(1,3)-glucanase.
Proteomic analysis of proteins released from growth-arrested Candida albicans following exposure to caspofungin.
The MAP kinase-activated protein kinase Rck2p regulates cellular responses to cell wall stresses, filamentation and virulence in the human fungal pathogen Candida albicans.
The major exoglucanase from Candida albicans: a non-glycosylated secretory monomer related to its counterpart from Saccharomyces cerevisiae.
The structure of the exo-beta-(1,3)-glucanase from Candida albicans in native and bound forms: relationship between a pocket and groove in family 5 glycosyl hydrolases.
The pH-dependent conformational change of eukaryotic translation initiation factor 5: Insights into partner-binding manner.
Candida albicans biofilm-defective mutants.
Candida albicans Zcf37, a zinc finger protein, is required for stabilization of the white state.
Candida albicans protein kinase CK2 governs virulence during oropharyngeal candidiasis.
Candida albicans possesses Sap7 as a pepstatin A-insensitive secreted aspartic protease.
Induction of SAP7 correlates with virulence in an intravenous infection model of candidiasis but not in a vaginal infection model in mice.
A conserved mitogen-activated protein kinase pathway is required for mating in Candida albicans.
Aromatic amino-acid biosynthesis in Candida albicans: identification of the ARO4 gene encoding a second DAHP synthase.
Candida albicans sterol C-14 reductase, encoded by the ERG24 gene, as a potential antifungal target site.
Isolation and sequence of the gene encoding ornithine decarboxylase, SPE1, from Candida albicans by complementation of a spe1 delta strain of Saccharomyces cerevisiae.
The ornithine decarboxylase gene from Candida albicans. Sequence analysis and expression during dimorphism.
Factors supporting cysteine tolerance and sulfite production in Candida albicans.
Evidence for the presence of pir-like proteins in Candida albicans.
Role of Pir1 in the construction of the Candida albicans cell wall.
The cell wall architecture of Candida albicans wild-type cells and cell wall-defective mutants.
A fungal family of transcriptional regulators: the zinc cluster proteins.
New tools for phenotypic analysis in Candida albicans: the WAR1 gene confers resistance to sorbate.
Candida albicans cyclin Clb4 carries S-phase cyclin activity.
Cdc28 provides a molecular link between Hsp90, morphogenesis, and cell cycle progression in Candida albicans.
Contribution of Candida albicans cell wall components to recognition by and escape from murine macrophages.
Plagiochin E, an antifungal active macrocyclic bis(bibenzyl), induced apoptosis in Candida albicans through a metacaspase-dependent apoptotic pathway.
The mitotic cyclins Clb2p and Clb4p affect morphogenesis in Candida albicans.
Defective hyphal development and avirulence caused by a deletion of the SSK1 response regulator gene in Candida albicans.
Deletion of the SSK1 response regulator gene in Candida albicans contributes to enhanced killing by human polymorphonuclear neutrophils.
Histidine kinase, two-component signal transduction proteins of Candida albicans and the pathogenesis of candidosis.
Identification of a putative response regulator two-component phosphorelay gene (CaSSK1) from Candida albicans.
Cloning and expression of squalene epoxidase from the pathogenic yeast Candida albicans.
Inhibition of squalene epoxidase by allylamine antimycotic compounds. A comparative study of the fungal and mammalian enzymes.
Properties of a particulate squalene epoxidase from Candida albicans.
Squalene epoxidase encoded by ERG1 affects morphogenesis and drug susceptibilities of Candida albicans.
The Candida albicans-specific gene EED1 encodes a key regulator of hyphal extension.
Tyrosol is a quorum-sensing molecule in Candida albicans.
A zinc finger protein from Candida albicans is involved in sucrose utilization.
PHR2 of Candida albicans encodes a functional homolog of the pH-regulated gene PHR1 with an inverted pattern of pH-dependent expression.
Sequence and transcript analysis of the C. albicans URA3 gene encoding orotidine-5'-phosphate decarboxylase.
Detailed comparison of Candida albicans and Candida glabrata biofilms under different conditions and their susceptibility to caspofungin and anidulafungin.
Distinct domains of the Candida albicans adhesin Eap1p mediate cell-cell and cell-substrate interactions.
EAP1, a Candida albicans gene involved in binding human epithelial cells.
Eap1p, an adhesin that mediates Candida albicans biofilm formation in vitro and in vivo.
Molecular cloning and analysis of the NAG1 cDNA coding for glucosamine-6-phosphate deaminase from Candida albicans.
Identification and characterization of a Candida albicans mating pheromone.
Deletion of the high-affinity cAMP phosphodiesterase encoded by PDE2 affects stress responses and virulence in Candida albicans.
Alpha-pheromone-induced 'shmooing' and gene regulation require white-opaque switching during Candida albicans mating.
Intra- and intermolecular events direct the propeptide-mediated maturation of the Candida albicans secreted aspartic proteinase Sap1p.
Misexpression of the opaque-phase-specific gene PEP1 (SAP1) in the white phase of Candida albicans confers increased virulence in a mouse model of cutaneous infection.
Transcription of the gene for a pepsinogen, PEP1, is regulated by white-opaque switching in Candida albicans.
X-ray structures of Sap1 and Sap5: structural comparison of the secreted aspartic proteinases from Candida albicans.
Structural analysis of a fungal methionine synthase with substrates and inhibitors.
Structure of Candida albicans methionine synthase determined by employing surface residue mutagenesis.
The cobalamin-independent methionine synthase enzyme captured in a substrate-induced closed conformation.
Decoding serological response to Candida cell wall immunome into novel diagnostic, prognostic, and therapeutic candidates for systemic candidiasis by proteomic and bioinformatic analyses.
Kinetics of beta-1,3 glucan interaction at the donor and acceptor sites of the fungal glucosyltransferase encoded by the BGL2 gene.
Localisation of Bgl2p upon antifungal drug treatment in Candida albicans.
Phenotype in Candida albicans of a disruption of the BGL2 gene encoding a 1,3-beta-glucosyltransferase.
Two-dimensional gel electrophoresis as analytical tool for identifying Candida albicans immunogenic proteins.
The structure of the Candida albicans Ess1 prolyl isomerase reveals a well-ordered linker that restricts domain mobility.
Cloning of Candida albicans SEC14 gene homologue coding for a putative essential function.
Two transcripts, differing at their 3' ends, are produced from the Candida albicans SEC14 gene.
Snf7p, a component of the ESCRT-III protein complex, is an upstream member of the RIM101 pathway in Candida albicans.
Aft2, a novel transcription regulator, is required for iron metabolism, oxidative stress, surface adhesion and hyphal development in Candida albicans.
Role of Candida albicans Aft2p transcription factor in ferric reductase activity, morphogenesis and virulence.
Functional characterization of CaCBF1, the Candida albicans homolog of centromere binding factor 1.
The centromere-binding factor Cbf1p from Candida albicans complements the methionine auxotrophic phenotype of Saccharomyces cerevisiae.
Sequencing of a 4.3 kbp region of chromosome 2 of Candida albicans reveals the presence of homologues of SHE9 from Saccharomyces cerevisiae and of bacterial phosphatidylinositol-phospholipase C.
Structural basis for Mep2 ammonium transceptor activation by phosphorylation.
Identification of Candida albicans ALS2 and ALS4 and localization of als proteins to the fungal cell surface.
Secretion and filamentation are mediated by the Candida albicans t-SNAREs Sso2p and Sec9p.
Sequence of a dihydrofolate reductase-encoding gene from Candida albicans.
3-phosphoglycerate kinase: a glycolytic enzyme protein present in the cell wall of Candida albicans.
A phosphatidylinositol 3-kinase of Candida albicans: molecular cloning and characterization.
Generation and functional in vivo characterization of a lipid kinase defective phosphatidylinositol 3-kinase Vps34p of Candida albicans.
The deletion of CaVPS34 in the human pathogenic yeast Candida albicans causes defects in vesicle-mediated protein sorting and nuclear segregation.
The phosphatidylinositol 3-kinase Vps34p of the human pathogenic yeast Candida albicans is a multifunctional protein that interacts with the putative vacuolar H+ -ATPase subunit Vma7p.
Self-regulation of Candida albicans population size during GI colonization.
4-oxatetradecanoic acid is fungicidal for Cryptococcus neoformans and inhibits replication of human immunodeficiency virus I.
Cloning and characterization of the gene encoding the ADP-ribosylation factor in Candida albicans.
Candida albicans-conditioned medium protects yeast cells from oxidative stress: a possible link between quorum sensing and oxidative stress resistance.
Farnesol-induced apoptosis in Candida albicans is mediated by Cdr1-p extrusion and depletion of intracellular glutathione.
CDC42 is required for polarized growth in human pathogen Candida albicans.
Candida albicans killing by RAW 264.7 mouse macrophage cells: effects of Candida genotype, infection ratios, and gamma interferon treatment.
Correlation between virulence of Candida albicans mutants in mice and Galleria mellonella larvae.
Inhibition of the pathogenically related morphologic transition in Candida albicans by disrupting Cdc42 binding to its effectors.
Virulence and hyphal formation of Candida albicans require the Ste20p-like protein kinase CaCla4p.
Candida albicans CDK1 and CYB1: cDNA homologues of the cdc2/CDC28 and cdc13/CLB1/CLB2 cell cycle control genes.
Defining Candida albicans stationary phase by cellular and DNA replication, gene expression and regulation.
Hyphal elongation is regulated independently of cell cycle in Candida albicans.
Rfa2 is specifically dephosphorylated by Pph3 in Candida albicans.
Identification and study of a Candida albicans protein homologous to Saccharomyces cerevisiae Ssr1p, an internal cell-wall protein.
Identification of an N-acetylglucosamine transporter that mediates hyphal induction in Candida albicans.
Candida albicans biofilms: a developmental state associated with specific and stable gene expression patterns.
Cloning and sequencing of the Candida albicans C-4 sterol methyl oxidase gene (ERG25) and expression of an ERG25 conditional lethal mutation in Saccharomyces cerevisiae.
Complete inventory of ABC proteins in human pathogenic yeast, Candida albicans.
Functional analysis of a vacuolar ABC transporter in wild-type Candida albicans reveals its involvement in virulence.
Proteomic analysis of Rta2p-dependent raft-association of detergent-resistant membranes in Candida albicans.
Expansion of the aspartate beta-semialdehyde dehydrogenase family: the first structure of a fungal ortholog.
A Candida albicans homolog of a human cyclophilin gene encodes a peptidyl-prolyl cis-trans isomerase.
cDNA array analysis of the differential expression change in virulence-related genes during the development of resistance in Candida albicans.
Genome-wide expression profile analysis reveals coordinately regulated genes associated with stepwise acquisition of azole resistance in Candida albicans clinical isolates.
Cloning and disruption of caPLB1, a phospholipase B gene involved in the pathogenicity of Candida albicans.
DNA microarray analysis of fluconazole resistance in a laboratory Candida albicans strain.
The cryo-EM structure of a gamma-TuSC elucidates architecture and regulation of minimal microtubule nucleation systems.
Kinesin-8-specific loop-2 controls the dual activities of the motor domain according to tubulin protofilament shape.
Identification of GIG1, a GlcNAc-induced gene in Candida albicans needed for normal sensitivity to the chitin synthase inhibitor nikkomycin Z.
N-acetylglucosamine (GlcNAc) induction of hyphal morphogenesis and transcriptional responses in Candida albicans are not dependent on its metabolism.
Homologs of the yeast neck filament associated genes: isolation and sequence analysis of Candida albicans CDC3 and CDC10.
Hemoglobin regulates expression of an activator of mating-type locus alpha genes in Candida albicans.
Induction of a high affinity fibronectin receptor in Candida albicans by caspofungin: requirements for beta (1,6) glucans and the developmental regulator Hbr1p.
Hyphal guidance and invasive growth in Candida albicans require the Ras-like GTPase Rsr1p and its GTPase-activating protein Bud2p.
Rsr1 focuses Cdc42 activity at hyphal tips and promotes maintenance of hyphal development in Candida albicans.
Candida albicans VAC8 is required for vacuolar inheritance and normal hyphal branching.
Potent in vitro synergism of fluconazole and osthole against fluconazole-resistant Candida albicans.
A common drug-responsive element mediates the upregulation of the Candida albicans ABC transporters CDR1 and CDR2, two genes involved in antifungal drug resistance.
ABC transporter Cdr1p contributes more than Cdr2p does to fluconazole efflux in fluconazole-resistant Candida albicans clinical isolates.
ABC transporters Cdr1p, Cdr2p and Cdr3p of a human pathogen Candida albicans are general phospholipid translocators.
Adherence of Candida albicans to silicone induces immediate enhanced tolerance to fluconazole.
Adriamycin alters the expression of drug efflux pumps and confers amphotericin B tolerance in Candida albicans.
Alanine scanning of all cysteines and construction of a functional cysteine-less Cdr1p, a multidrug ABC transporter of Candida albicans.
Alanine scanning of transmembrane helix 11 of Cdr1p ABC antifungal efflux pump of Candida albicans: identification of amino acid residues critical for drug efflux.
Antagonism of azole activity against Candida albicans following induction of multidrug resistance genes by selected antimicrobial agents.
Antimicrobial peptides enhance the candidacidal activity of antifungal drugs by promoting the efflux of ATP from Candida cells.
Asymmetric distribution of phosphatidylethanolamine in C. albicans: possible mediation by CDR1, a multidrug transporter belonging to ATP binding cassette (ABC) superfamily.
CDR1, a multidrug resistance gene from Candida albicans, contains multiple regulatory domains in its promoter and the distal AP-1 element mediates its induction by miconazole.
CaNdt80 is involved in drug resistance in Candida albicans by regulating CDR1.
Candida drug resistance protein 1, a major multidrug ATP binding cassette transporter of Candida albicans, translocates fluorescent phospholipids in a reconstituted system.
Characterisation of human steroid hormone transport mediated by Cdr1p, a multidrug transporter of Candida albicans, belonging to the ATP binding cassette super family.
Characterization of Cdr1p, a major multidrug efflux protein of Candida albicans: purified protein is amenable to intrinsic fluorescence analysis.
Chimeras of the ABC drug transporter Cdr1p reveal functional indispensability of transmembrane domains and nucleotide-binding domains, but transmembrane segment 12 is replaceable with the corresponding homologous region of the non-drug transporter Cdr3p.
Deletion of transmembrane domain 12 of CDR1, a multidrug transporter from Candida albicans, leads to altered drug specificity: expression of a yeast multidrug transporter in baculovirus expression system.
Disulfiram is a potent modulator of multidrug transporter Cdr1p of Candida albicans.
Divergent signature motifs of nucleotide binding domains of ABC multidrug transporter, CaCdr1p of pathogenic Candida albicans, are functionally asymmetric and noninterchangeable.
Doxorubicin induces drug efflux pumps in Candida albicans.
Drug susceptibilities of yeast cells are affected when expressing mutant Candida albicans drug resistance protein.
Expression of CDR1, a multidrug resistance gene of Candida albicans: transcriptional activation by heat shock, drugs and human steroid hormones.
Expression of the CDR1 efflux pump in clinical Candida albicans isolates is controlled by a negative regulatory element.
Fcr1p inhibits development of fluconazole resistance in Candida albicans by abolishing CDR1 induction.
Functional characterization of Candida albicans ABC transporter Cdr1p.
Functional characterization of N-terminal nucleotide binding domain (NBD-1) of a major ABC drug transporter Cdr1p of Candida albicans: uncommon but conserved Trp326 of Walker B is important for ATP binding.
Functional expression of Candida albicans drug efflux pump Cdr1p in a Saccharomyces cerevisiae strain deficient in membrane transporters.
Functional similarities and differences between Candida albicans Cdr1p and Cdr2p transporters.
Identification of a negative regulatory element which regulates basal transcription of a multidrug resistance gene CDR1 of Candida albicans.
Induced expression of the Candida albicans multidrug resistance gene CDR1 in response to fluconazole and other antifungals.
Insight into pleiotropic drug resistance ATP-binding cassette pump drug transport through mutagenesis of Cdr1p transmembrane domains.
Key physiological differences in Candida albicans CDR1 induction by steroid hormones and antifungal drugs.
Membrane fluidity affects functions of Cdr1p, a multidrug ABC transporter of Candida albicans.
Mitochondria influence CDR1 efflux pump activity, Hog1-mediated oxidative stress pathway, iron homeostasis, and ergosterol levels in Candida albicans.
Molecular determinants of transient and reversible induced up-regulation of CaCDR1 in azole susceptible clinical isolates of Candida albicans.
Multidrug transporters CaCdr1p and CaMdr1p of Candida albicans display different lipid specificities: both ergosterol and sphingolipids are essential for targeting of CaCdr1p to membrane rafts.
Multiple efflux mechanisms are involved in Candida albicans fluconazole resistance.
Ncb2 is involved in activated transcription of CDR1 in azole-resistant clinical isolates of Candida albicans.
Persistent Candida albicans colonization and molecular mechanisms of azole resistance in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) patients.
Purification and characterization of the N-terminal nucleotide binding domain of an ABC drug transporter of Candida albicans: uncommon cysteine 193 of Walker A is critical for ATP hydrolysis.
Regulated overexpression of CDR1 in Candida albicans confers multidrug resistance.
Relative contributions of the Candida albicans ABC transporters Cdr1p and Cdr2p to clinical azole resistance.
SRE1 and SRE2 are two specific steroid-responsive modules of Candida drug resistance gene 1 (CDR1) promoter.
Serum repressing efflux pump CDR1 in Candida albicans.
Substitution of threonine-1351 in the multidrug transporter Cdr1p of Candida albicans results in hypersusceptibility to antifungal agents and threonine-1351 is essential for synergic effects of calcineurin inhibitor FK520.
Synergistic mechanisms of retigeric acid B and azoles against Candida albicans.
TAC1, transcriptional activator of CDR genes, is a new transcription factor involved in the regulation of Candida albicans ABC transporters CDR1 and CDR2.
The DNA-binding domain of CaNdt80p is required to activate CDR1 involved in drug resistance in Candida albicans.
The amino acid residues of transmembrane helix 5 of multidrug resistance protein CaCdr1p of Candida albicans are involved in substrate specificity and drug transport.
Time course of microbiologic outcome and gene expression in Candida albicans during and following in vitro and in vivo exposure to fluconazole.
Transcriptional activation and increased mRNA stability contribute to overexpression of CDR1 in azole-resistant Candida albicans.
Transcriptional analyses of antifungal drug resistance in Candida albicans.
Transcriptional regulation of drug-resistance genes in Candida albicans biofilms in response to antifungals.
A role for amyloid in cell aggregation and biofilm formation.
Candida albicans Als adhesins have conserved amyloid-forming sequences.
Candida albicans and Saccharomyces cerevisiae expressing ALA1/ALS5 adhere to accessible threonine, serine, or alanine patches.
Expression, cloning, and characterization of a Candida albicans gene, ALA1, that confers adherence properties upon Saccharomyces cerevisiae for extracellular matrix proteins.
Force-induced formation and propagation of adhesion nanodomains in living fungal cells.
Global cell surface conformational shift mediated by a Candida albicans adhesin.
Overexpression of the Candida albicans ALA1 gene in Saccharomyces cerevisiae results in aggregation following attachment of yeast cells to extracellular matrix proteins, adherence properties similar to those of Candida albicans.
Damage to the glycoshield activates PMT-directed O-mannosylation via the Msb2-Cek1 pathway in Candida albicans.
Proteomic analysis of detergent-resistant membranes from Candida albicans.
Distinct roles of Candida albicans drug resistance transcription factors TAC1, MRR1, and UPC2 in virulence.
Multidrug-resistant transporter mdr1p-mediated uptake of a novel antifungal compound.
Mutations in the multi-drug resistance regulator MRR1, followed by loss of heterozygosity, are the main cause of MDR1 overexpression in fluconazole-resistant Candida albicans strains.
The stepwise acquisition of fluconazole resistance mutations causes a gradual loss of fitness in Candida albicans.
Candida albicans scavenges host zinc via Pra1 during endothelial invasion.
Cloning and characterization of PRA1, a gene encoding a novel pH-regulated antigen of Candida albicans.
Cloning of a cDNA fragment encoding part of the protein moiety of the 58-kDa fibrinogen-binding mannoprotein of Candida albicans.
Comparative study of the C3d receptor and 58-kilodalton fibrinogen-binding mannoproteins of Candida albicans.
Complement regulator Factor H mediates a two-step uptake of Streptococcus pneumoniae by human cells.
Expression of the fibrinogen binding mannoprotein and the laminin receptor of Candida albicans in vitro and in infected tissues.
Heterogeneous surface distribution of the fibrinogen-binding protein on Candida albicans.
Identification of a 58-kilodalton cell surface fibrinogen-binding mannoprotein from Candida albicans.
Identification of continuous B-cell epitopes on the protein moiety of the 58-kiloDalton cell wall mannoprotein of Candida albicans belonging to a family of immunodominant fungal antigens.
Immune evasion of the human pathogenic yeast Candida albicans: Pra1 is a Factor H, FHL-1 and plasminogen binding surface protein.
Integrin alphaXbeta(2) is a leukocyte receptor for Candida albicans and is essential for protection against fungal infections.
Molecular determinants of the interaction between human high molecular weight kininogen and Candida albicans cell wall: Identification of kininogen-binding proteins on fungal cell wall and mapping the cell wall-binding regions on kininogen molecule.
Regulation of innate immune response to Candida albicans infections by alphaMbeta2-Pra1p interaction.
Role of pH-regulated antigen 1 of Candida albicans in the fungal recognition and antifungal response of human neutrophils.
Secreted pH-regulated antigen 1 of Candida albicans blocks activation and conversion of complement C3.
The pH-regulated antigen 1 of Candida albicans binds the human complement inhibitor C4b-binding protein and mediates fungal complement evasion.
An analysis of the impact of NRG1 overexpression on the Candida albicans response to specific environmental stimuli.
CaSPA2 is important for polarity establishment and maintenance in Candida albicans.
Candida albicans transcription factor Rim101 mediates pathogenic interactions through cell wall functions.
Differential expression of the NRG1 repressor controls species-specific regulation of chlamydospore development in Candida albicans and Candida dubliniensis.
Drosophila melanogaster as a facile model for large-scale studies of virulence mechanisms and antifungal drug efficacy in Candida species.
Efficacy of a genetically engineered Candida albicans tet-NRG1 strain as an experimental live attenuated vaccine against hematogenously disseminated candidiasis.
Engineered control of cell morphology in vivo reveals distinct roles for yeast and filamentous forms of Candida albicans during infection.
Expression of one-hybrid fusions with Staphylococcus aureus lexA in Candida albicans confirms that Nrg1 is a transcriptional repressor and that Gcn4 is a transcriptional activator.
Inhibition of filamentation can be used to treat disseminated candidiasis.
NRG1, a repressor of filamentous growth in C.albicans, is down-regulated during filament induction.
The bacterial signalling molecule indole attenuates the virulence of the fungal pathogen Candida albicans.
The transcriptional regulator Nrg1p controls Candida albicans biofilm formation and dispersion.
Transcriptional profiling of the early stages of germination in Candida albicans by real-time RT-PCR.
Use of a genetically engineered strain to evaluate the pathogenic potential of yeast cell and filamentous forms during Candida albicans systemic infection in immunodeficient mice.
Isolation and characterization of the Candida albicans gene for mRNA 5'-triphosphatase: association of mRNA 5'-triphosphatase and mRNA 5'-guanylyltransferase activities is essential for the function of mRNA 5'-capping enzyme in vivo.
Pga13 in Candida albicans is localized in the cell wall and influences cell surface properties, morphogenesis and virulence.
Regulation of the Candida albicans cell wall damage response by transcription factor Sko1 and PAS kinase Psk1.
The crystal structure of the secreted aspartic proteinase 3 from Candida albicans and its complex with pepstatin A.
Characterization of Hwp2, a Candida albicans putative GPI-anchored cell wall protein necessary for invasive growth.
The Candida albicans Hwp2 is necessary for proper adhesion, biofilm formation and oxidative stress tolerance.
The Candida albicans Hwp2p can complement the lack of filamentation of a Saccharomyces cerevisiae flo11 null strain.
A functional analysis of the Candida albicans homolog of Saccharomyces cerevisiae VPS4.
Candida albicans VPS4 contributes differentially to epithelial and mucosal pathogenesis.
Candida albicans VPS4 is required for secretion of aspartyl proteases and in vivo virulence.
Mutational analysis of Candida albicans SNF7 reveals genetically separable Rim101 and ESCRT functions and demonstrates divergence in bro1-domain protein interactions.
The Candida albicans ESCRT pathway makes Rim101-dependent and -independent contributions to pathogenesis.
The beta-arrestin-like protein Rim8 is hyperphosphorylated and complexes with Rim21 and Rim101 to promote adaptation to neutral-alkaline pH.
Phosphoregulation of Nap1 plays a role in septin ring dynamics and morphogenesis in Candida albicans.
Cross-species and cross-compartmental aminoacylation of isoaccepting tRNAs by a class II tRNA synthetase.
Sequence analysis of Candida albicans phosphoribosyl-aminoimidazole carboxylase (ADE2) gene.
Sequence analysis of the Candida albicans ADE2 gene and physical separation of the two functionally distinct domains of the phosphoribosylaminoimidazole carboxylase.
Candida albicans lacking the gene encoding the regulatory subunit of protein kinase A displays a defect in hyphal formation and an altered localization of the catalytic subunit.
Genome-wide fitness test and mechanism-of-action studies of inhibitory compounds in Candida albicans.
Orchestrated actin nucleation by the Candida albicans polarisome complex enables filamentous growth.
Crystal Structure of histidine triad nucleotide-binding protein from the pathogenic fungus Candida albicans.
Pseudomonas aeruginosa lipopolysaccharide inhibits Candida albicans hyphae formation and alters gene expression during biofilm development.
Candida albicans Rho-type GTPase-encoding genes required for polarized cell growth and cell separation.
An antisense-based functional genomics approach for identification of genes critical for growth of Candida albicans.
The ALS5 gene of Candida albicans and analysis of the Als5p N-terminal domain.
Autophagy regulation of ATG13 and ATG27 on biofilm formation and antifungal resistance in Candida albicans.
The MET3 promoter: a new tool for Candida albicans molecular genetics.
Multiple functions of Pmt1p-mediated protein O-mannosylation in the fungal pathogen Candida albicans.
Pmt-mediated O mannosylation stabilizes an essential component of the secretory apparatus, Sec20p, in Candida albicans.
Protein O-mannosyltransferase isoforms regulate biofilm formation in Candida albicans.
Commercial AHAS-inhibiting herbicides are promising drug leads for the treatment of human fungal pathogenic infections.
Comparison of myristoyl-CoA:protein N-myristoyltransferases from three pathogenic fungi: Cryptococcus neoformans, Histoplasma capsulatum, and Candida albicans.
Crystal structure of the anti-fungal target N-myristoyl transferase.
Crystal structures of Candida albicans N-myristoyltransferase with two distinct inhibitors.
Scanning alanine mutagenesis and de-peptidization of a Candida albicans myristoyl-CoA:protein N-myristoyltransferase octapeptide substrate reveals three elements critical for molecular recognition.
The Candida albicans myristoyl-CoA:protein N-myristoyltransferase gene. Isolation and expression in Saccharomyces cerevisiae and Escherichia coli.
The evolutionary rewiring of the ribosomal protein transcription pathway modifies the interaction of transcription factor heteromer Ifh1-Fhl1 (interacts with forkhead 1-forkhead-like 1) with the DNA-binding specificity element.
Adaptation to environmental pH: integrating the Rim101 and calcineurin signal transduction pathways.
The Candida albicans PMM1 gene encoding phosphomannomutase complements a Saccharomyces cerevisiae sec 53-6 mutation.
A clinical isolate of Candida albicans with mutations in ERG11 (encoding sterol 14alpha-demethylase) and ERG5 (encoding C22 desaturase) is cross resistant to azoles and amphotericin B.
Differential regulation of SAP8 and SAP9, which encode two new members of the secreted aspartic proteinase family in Candida albicans.
The glycosylphosphatidylinositol-anchored protease Sap9 modulates the interaction of Candida albicans with human neutrophils.
Antimicrobial peptide MUC7 12-mer activates the calcium/calcineurin pathway in Candida albicans.
Farnesol-induced apoptosis in Candida albicans.
Investigating the function of Ddr48p in Candida albicans.
The Candida albicans Ddr48 protein is essential for filamentation, stress response, and confers partial antifungal drug resistance.
The transcription factor homolog CTF1 regulates {beta}-oxidation in Candida albicans.
A Candida albicans cell wall-linked protein promotes invasive filamentation into semi-solid medium.
Calmodulin binding to Dfi1p promotes invasiveness of Candida albicans.
A novel functional assay for fungal histidine kinases group III reveals the role of HAMP domains for fungicide sensitivity.
COS-l, a putative two-component histidine kinase of Candida albicans, is an in vivo virulence factor.
COS1, a two-component histidine kinase that is involved in hyphal development in the opportunistic pathogen Candida albicans.
Deletion of the HAMP domains from the histidine kinase CaNik1p of Candida albicans or treatment with fungicides activates the MAP kinase Hog1p in S. cerevisiae transformants.
The two-component hybrid kinase regulator CaNIK1 of Candida albicans.
An endocytic mechanism for haemoglobin-iron acquisition in Candida albicans.
Potential anti-infective targets in pathogenic yeasts: structure and properties of 3,4-dihydroxy-2-butanone 4-phosphate synthase of Candida albicans.
Characterization of the Saccharomyces cerevisiae FCY1 gene encoding cytosine deaminase and its homologue FCA1 of Candida albicans.
Attenuation of virulence and changes in morphology in Candida albicans by disruption of the N-acetylglucosamine catabolic pathway.
N-acetylglucosamine kinase, HXK1 contributes to white-opaque morphological transition in Candida albicans.
The inducible N-acetylglucosamine catabolic pathway gene cluster in Candida albicans: discrete N-acetylglucosamine-inducible factors interact at the promoter of NAG1.
Use of the porcine intestinal epithelium (PIE)-assay to analyze early stages of colonization by the human fungal pathogen Candida albicans.
Nonorthologous gene displacement of phosphomevalonate kinase.
Identification of sumoylation targets, combined with inactivation of SMT3, reveals the impact of sumoylation upon growth, morphology, and stress resistance in the pathogen Candida albicans.
Role of TFP1 in vacuolar acidification, oxidative stress and filamentous development in Candida albicans.
Msb2 signaling mucin controls activation of Cek1 mitogen-activated protein kinase in Candida albicans.
The Cek1 MAPK is a short-lived protein regulated by quorum sensing in the fungal pathogen Candida albicans.
The Sho1 adaptor protein links oxidative stress to morphogenesis and cell wall biosynthesis in the fungal pathogen Candida albicans.
Candida albicans sphingolipid C9-methyltransferase is involved in hyphal elongation.
Defensins from insects and plants interact with fungal glucosylceramides.
Glucosylceramide synthases, a gene family responsible for the biosynthesis of glucosphingolipids in animals, plants, and fungi.
The Candida albicans pescadillo homolog is required for normal hypha-to-yeast morphogenesis and yeast proliferation.
Candida albicans phosphatidylinositol synthase has common features with both Saccharomyces cerevisiae and mammalian phosphatidylinositol synthases.
Function of the phosphatidylinositol synthase Pis1 in maintenance of endoplasmic reticulum function and pathogenicity in Candida albicans.
Crystal structures of aminotransferases Aro8 and Aro9 from Candida albicans and structural insights into their properties.
Cloning of the Candida albicans HIS1 gene by direct complementation of a C. albicans histidine auxotroph using an improved double-ARS shuttle vector.
Divergent functions of three Candida albicans zinc-cluster transcription factors (CTA4, ASG1 and CTF1) complementing pleiotropic drug resistance in Saccharomyces cerevisiae.
Oma1 links mitochondrial protein quality control and TOR signaling to modulate physiological plasticity and cellular stress responses.
Differential extraction of N-acetylglucosaminidase and trehalase from the cell envelope of Candida albicans.
Disruption of the Candida albicans ATC1 gene encoding a cell-linked acid trehalase decreases hypha formation and infectivity without affecting resistance to oxidative stress.
On the biochemical classification of yeast trehalases: Candida albicans contains two enzymes with mixed features of neutral and acid trehalase activities.
The ATC1 gene encodes a cell wall-linked acid trehalase required for growth on trehalose in Candida albicans.
Trehalose and glycogen levels during the initial stages of growth of Candida albicans.
Activation of the heat shock transcription factor Hsf1 is essential for the full virulence of the fungal pathogen Candida albicans.
Hsp90 orchestrates transcriptional regulation by Hsf1 and cell wall remodelling by MAPK signalling during thermal adaptation in a pathogenic yeast.
Identification of a gene encoding the pyruvate decarboxylase gene regulator CaPdc2p from Candida albicans.
Modelling the regulation of thermal adaptation in Candida albicans, a major fungal pathogen of humans.
Role of the heat shock transcription factor, Hsf1, in a major fungal pathogen that is obligately associated with warm-blooded animals.
Elongation factor 3 (EF-3) from Candida albicans shows both structural and functional similarity to EF-3 from Saccharomyces cerevisiae.
Isolation and sequence analysis of the gene encoding translation elongation factor 3 from Candida albicans.
Isolation and sequence analysis of the gene for translation elongation factor 3 from Candida albicans.
Structure and regulation of a Candida albicans RP10 gene which encodes an immunogenic protein homologous to Saccharomyces cerevisiae ribosomal protein 10.
Cloning and sequence of a 3.835 kbp DNA fragment containing the HIS4 gene and a fragment of a PEX5-like gene from Candida albicans.
Catalase gene disruptant of the human pathogenic yeast Candida albicans is defective in hyphal growth, and a catalase-specific inhibitor can suppress hyphal growth of wild-type cells.
Cloning and sequencing of a Candida albicans catalase gene and effects of disruption of this gene.
Functional analysis of Candida albicans genes whose Saccharomyces cerevisiae homologues are involved in endocytosis.
Cloning of a DNA fragment encoding part of a 70-kDa heat shock protein of Candida albicans.
Molecular cloning and expression of a 70-kilodalton heat shock protein of Candida albicans.
Conservation of a portion of the S. cerevisiae Ure2p prion domain that interacts with the full-length protein.
Active and passive immunization with rHyr1p-N protects mice against hematogenously disseminated candidiasis.
Hyphal tip-associated localization of Cdc42 is F-actin dependent in Candida albicans.
The Candida albicans HYR1 gene, which is activated in response to hyphal development, belongs to a gene family encoding yeast cell wall proteins.
Ash1 protein, an asymmetrically localized transcriptional regulator, controls filamentous growth and virulence of Candida albicans.
Characterization of Candida albicans ASH1 in Saccharomyces cerevisiae.
Specialized sugar sensing in diverse fungi.
Inhibition of fungal pathogenicity by targeting the H2S-synthesizing enzyme cystathionine beta-synthase.
Inhibition of fungal pathogenicity by targeting the Hpisub>2pi/sub>S-synthesizing enzyme cystathionine beta-synthase.
Hsp21 potentiates antifungal drug tolerance in Candida albicans.
Non-glucan attached proteins of Candida albicans biofilm formed on various surfaces.
Small but crucial: the novel small heat shock protein Hsp21 mediates stress adaptation and virulence in Candida albicans.
Comparative transcript profiling of Candida albicans and Candida dubliniensis identifies SFL2, a C. albicans gene required for virulence in a reconstituted epithelial infection model.
Pga26 mediates filamentation and biofilm formation and is required for virulence in Candida albicans.
DNA array analysis of Candida albicans gene expression in response to adherence to polystyrene.
The role of Candida albicans SPT20 in filamentation, biofilm formation and pathogenesis.
Over-expression of Candida albicans mitochondrial ribosomal protein S9 (MrpS9p) disturbs mitochondrial function in Saccharomyces cerevisiae.
A Candida albicans 37 kDa polypeptide with homology to the laminin receptor is a component of the translational machinery.
Evidence for the presence of a high-affinity laminin receptor-like molecule on the surface of Candida albicans yeast cells.
A Candida albicans chaperonin subunit (CaCct8p) as a suppressor of morphogenesis and Ras phenotypes in C. albicans and Saccharomyces cerevisiae.
A potential phosphorylation site for an A-type kinase in the Efg1 regulator protein contributes to hyphal morphogenesis of Candida albicans.
A role for Efg1p in Candida albicans interactions with extracellular matrices.
Chlamydospore formation in Candida albicans requires the Efg1p morphogenetic regulator.
Control of white-opaque phenotypic switching in Candida albicans by the Efg1p morphogenetic regulator.
EFG1 null mutants of Candida albicans switch but cannot express the complete phenotype of white-phase budding cells.
Efg1 involved in drug resistance by regulating the expression of ERG3 in Candida albicans.
Functional mapping of the Candida albicans Efg1 regulator.
In vitro reconstructed human epithelia reveal contributions of Candida albicans EFG1 and CPH1 to adhesion and invasion.
Invasive lesions containing filamentous forms produced by a Candida albicans mutant that is defective in filamentous growth in culture.
Morphogenic regulator EFG1 affects the drug susceptibilities of pathogenic Candida albicans.
Nonfilamentous C. albicans mutants are avirulent.
Target specificity of the Candida albicans Efg1 regulator.
The filamentation pathway controlled by the Efg1 regulator protein is required for normal biofilm formation and development in Candida albicans.
The regulation of EFG1 in white-opaque switching in Candida albicans involves overlapping promoters.
Transcriptional regulators Cph1p and Efg1p mediate activation of the Candida albicans virulence gene SAP5 during infection.
Arginine 304 is an active site residue in phosphomannose isomerase from Candida albicans.
Cloning and heterologous expression of the Candida albicans gene PMI 1 encoding phosphomannose isomerase.
Identification of Cys-150 in the active site of phosphomannose isomerase from Candida albicans.
The X-ray crystal structure of phosphomannose isomerase from Candida albicans at 1.7-A resolution.
The role of secreted aspartyl proteinases in Candida albicans keratitis.