mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
small GTPase mediated signal transduction
Ubiquitin-like modifier conjugation pathway
sphingomyelin phosphodiesterase activity
alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity
N-acetylglucosamine-6-sulfatase activity
DNA-binding transcription factor activity, RNA polymerase II-specific
mRNA cleavage and polyadenylation specificity factor complex
DNA-binding transcription factor activity
ATP-dependent diacylglycerol kinase activity
protein kinase C-activating G protein-coupled receptor signaling pathway
negative regulation of apoptotic process
protein serine/threonine kinase activity
cellular modified amino acid catabolic process
gamma-glutamylaminecyclotransferase activity
3',5'-cyclic-nucleotide phosphodiesterase activity
positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
hydrolase activity, hydrolyzing O-glycosyl compounds
MAP kinase tyrosine/serine/threonine phosphatase activity
phosphatidylinositol phospholipase C activity
regulation of transcription by RNA polymerase II
homophilic cell adhesion via plasma membrane adhesion molecules
regulation of DNA-templated transcription
regulation of alternative mRNA splicing, via spliceosome
double-strand break repair via homologous recombination
phosphatidylinositol-3-phosphate binding
positive regulation of DNA-templated transcription
positive regulation of macromolecule metabolic process
post-translational protein targeting to endoplasmic reticulum membrane
generation of catalytic spliceosome for second transesterification step
ATP-dependent chromatin remodeler activity
cyclin-dependent protein serine/threonine kinase regulator activity
intracellular membrane-bounded organelle
glomerular basement membrane development
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
ammonium transmembrane transporter activity
regulation of response to reactive oxygen species
establishment of planar polarity involved in nephron morphogenesis
proteasome core complex, alpha-subunit complex
ubiquitin-dependent protein catabolic process
[acetyl-CoA carboxylase] kinase activity
[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity
positive regulation of cellular catabolic process
extracellular matrix structural constituent
Arp2/3 complex-mediated actin nucleation
retinoic acid receptor signaling pathway
regulation of monoatomic ion transmembrane transport
voltage-gated potassium channel activity
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
negative regulation of receptor signaling pathway via JAK-STAT
negative regulation of signal transduction
negative regulation of type II interferon-mediated signaling pathway
regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
regulation of tyrosine phosphorylation of STAT protein
mitochondrial outer membrane translocase complex
L-alpha-amino acid transmembrane transport
phosphatidylinositol bisphosphate binding
proton-transporting ATPase activity, rotational mechanism
proton-transporting V-type ATPase, V1 domain
S-adenosylmethionine-dependent methyltransferase activity
Guanosine 5'-monophosphate biosynthetic process
monocarboxylic acid transmembrane transporter activity
Nicotinamide adenine dinucleotide phosphate
Nicotinic adenine dinucleotide phosphate
isocitrate dehydrogenase (NADP+) activity
G protein-coupled receptor signaling pathway
purine-nucleoside phosphorylase activity
negative regulation of axon regeneration
posterior lateral line neuromast hair cell development
melanocyte-stimulating hormone receptor activity
positive regulation of apoptotic process
transcription initiation at RNA polymerase III promoter
non-membrane spanning protein tyrosine kinase activity
regulation of cellular component organization
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
COPII-coated ER to Golgi transport vesicle
endoplasmic reticulum to Golgi vesicle-mediated transport
endoplasmic reticulum-Golgi intermediate compartment membrane
retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
negative regulation of DNA-templated transcription
sodium:potassium-exchanging ATPase complex
methenyltetrahydrofolate cyclohydrolase activity
methylenetetrahydrofolate dehydrogenase (NADP+) activity
peptidyl-prolyl cis-trans isomerase activity
corticotropin-releasing hormone receptor 2 binding
positive regulation of cell cycle G2/M phase transition
cell communication by electrical coupling
slow-twitch skeletal muscle fiber contraction
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
deadenylation-dependent decapping of nuclear-transcribed mRNA
extracellular ligand-gated monoatomic ion channel activity
mRNA 5'-cap (guanine-N7-)-methyltransferase activity
proteasome-mediated ubiquitin-dependent protein catabolic process
transcription initiation at RNA polymerase II promoter
mitochondrial electron transport, ubiquinol to cytochrome c
mitochondrial respiratory chain complex III
RNA polymerase II cis-regulatory region sequence-specific DNA binding
extracellularly ATP-gated monoatomic cation channel activity
convergent extension involved in gastrulation
protein-arginine N-methyltransferase activity
L-methionine salvage from S-adenosylmethionine
L-methionine salvage from methylthioadenosine
S-methyl-5-thioribose-1-phosphate isomerase activity
G protein-coupled purinergic nucleotide receptor activity
phospholipase C-activating G protein-coupled receptor signaling pathway
polypeptide N-acetylgalactosaminyltransferase activity
mitochondrial respiratory chain complex III assembly
acetylgalactosaminyltransferase activity
phosphatidylinositol-4-phosphate binding
phosphotransferase activity, alcohol group as acceptor
hydrolase activity, acting on glycosyl bonds
Molybdenum cofactor biosynthetic process
Mo-molybdopterin cofactor biosynthetic process
Glycosylphosphatidylinositol anchor anabolism
Glycosylphosphatidylinositol anchor biosynthesis
Glycosylphosphatidylinositol anchor biosynthetic process
Glycosylphosphatidylinositol anchor formation
Glycosylphosphatidylinositol anchor synthesis
gamma-aminobutyric acid signaling pathway
vacuolar proton-transporting V-type ATPase, V0 domain
cyclin-dependent protein serine/threonine kinase inhibitor activity
negative regulation of transcription by RNA polymerase II
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
regulation of lipid biosynthetic process
negative regulation of integrin-mediated signaling pathway
protein import into peroxisome matrix, docking
acyltransferase activity, transferring groups other than amino-acyl groups
hydroxymethylglutaryl-CoA lyase activity
negative regulation of translational initiation
TIM22 mitochondrial import inner membrane insertion complex
protein insertion into mitochondrial inner membrane
protein transmembrane transporter activity
inorganic cation transmembrane transporter activity
monoatomic cation transmembrane transporter activity
ATP-dependent DNA damage sensor activity
proton-transporting ATP synthase complex assembly
negative regulation of cell population proliferation
positive regulation of cytosolic calcium ion concentration
obsolete regulation of neurotransmitter levels
hydrolase activity, acting on acid anhydrides
insulin-like growth factor receptor binding
phosphoenolpyruvate carboxykinase (GTP) activity
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
extrinsic component of mitochondrial inner membrane
Adenosine 5'-triphosphate biosynthetic process
Adenosine triphosphate biosynthetic process
proton-transporting ATP synthase activity, rotational mechanism
G-protein beta/gamma-subunit complex binding
positive regulation of neuron differentiation
spinal cord motor neuron differentiation
DNA-binding transcription activator activity, RNA polymerase II-specific
ubiquitin-protein transferase activator activity
inward rectifier potassium channel activity
protein tyrosine/serine/threonine phosphatase activity
NAD-dependent protein deacetylase activity
eukaryotic translation initiation factor 3 complex
formation of cytoplasmic translation initiation complex
transforming growth factor beta receptor signaling pathway
axon extension involved in axon guidance
tRNA (guanine(46)-N7)-methyltransferase activity
guanyl-nucleotide exchange factor activity
DNA-directed 5'-3' RNA polymerase activity
inositol tetrakisphosphate 1-kinase activity
inositol trisphosphate metabolic process
inositol-1,3,4-trisphosphate 5-kinase activity
inositol-1,3,4-trisphosphate 6-kinase activity
3',5'-cyclic-GMP phosphodiesterase activity
fatty acid elongation, monounsaturated fatty acid
fatty acid elongation, polyunsaturated fatty acid
fatty acid elongation, saturated fatty acid
long-chain fatty acid biosynthetic process
long-chain fatty-acyl-CoA biosynthetic process
unsaturated fatty acid biosynthetic process
very long-chain fatty acid biosynthetic process
chaperone-mediated protein complex assembly
oxidation-dependent protein catabolic process
protein quality control for misfolded or incompletely synthesized proteins
'de novo' GDP-L-fucose biosynthetic process
protein serine/threonine phosphatase activity
regulation of skeletal muscle fiber development
mRNA regulatory element binding translation repressor activity
dolichyl-diphosphooligosaccharide-protein glycotransferase activity
RNA polymerase I general transcription initiation factor activity
transcription initiation at RNA polymerase I promoter
adenylate cyclase-modulating G protein-coupled receptor signaling pathway
intraciliary transport involved in cilium assembly
THO complex part of transcription export complex
regulation of macromolecule metabolic process
L-arginine transmembrane transporter activity
L-leucine transmembrane transporter activity
regulation of cellular response to hypoxia
protoporphyrinogen IX biosynthetic process
mismatch base pair DNA N-glycosylase activity
proteolysis involved in protein catabolic process
convergent extension involved in axis elongation
cAMP-dependent protein kinase regulator activity
rRNA (adenine-N6,N6-)-dimethyltransferase activity
transcription elongation by RNA polymerase II
glucose-6-phosphate dehydrogenase activity
phosphogluconate dehydrogenase (decarboxylating) activity
epithelial cilium movement involved in extracellular fluid movement
histone H3K4 monomethyltransferase activity
negative regulation of actin filament polymerization
voltage-gated monoatomic ion channel activity
piccolo histone acetyltransferase complex
phosphotransferase activity, for other substituted phosphate groups
N-acylsphingosine amidohydrolase activity
RNA polymerase I transcription regulator complex
extracellularly glycine-gated chloride channel activity
transmembrane signaling receptor activity
maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
dehydrodolichyl diphosphate synthase activity
dehydrodolichyl diphosphate synthase complex
transferase activity, transferring alkyl or aryl (other than methyl) groups
epiboly involved in gastrulation with mouth forming second
regulation of actin filament organization
regulation of cellular component biogenesis
G protein-coupled serotonin receptor activity
glucosamine-6-phosphate deaminase activity
arachidonate 12(S)-lipoxygenase activity
alanine-glyoxylate transaminase activity
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
hydrolase activity, acting on ester bonds
acetylcholine-gated monoatomic cation-selective channel activity
pyrroline-5-carboxylate reductase activity
serine-type endopeptidase inhibitor activity
obsolete tRNA (adenine-N1)-methyltransferase activity
TIM23 mitochondrial import inner membrane translocase complex
protein import into mitochondrial matrix
mitochondrial electron transport, succinate to ubiquinone
Proton-transporting ATP synthase complex coupling factor F(0)
proton motive force-driven ATP synthesis
proton transmembrane transporter activity
proton-transporting ATP synthase complex, coupling factor F(o)
non-membrane spanning protein tyrosine phosphatase activity
NAD+-protein-arginine ADP-ribosyltransferase activity
hydroxymethylglutaryl-CoA reductase (NADPH) activity
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity
intramolecular phosphotransferase activity
alpha-(1->3)-fucosyltransferase activity
oxidized purine nucleobase lesion DNA N-glycosylase activity
calmodulin-dependent protein kinase activity
mitochondrial respiratory chain complex I assembly
transcription elongation by mitochondrial RNA polymerase
generation of catalytic spliceosome for first transesterification step
regulation of ARF protein signal transduction
nuclear-transcribed mRNA catabolic process
negative regulation of erythrocyte differentiation
adenylate cyclase-inhibiting adrenergic receptor signaling pathway
auditory receptor cell stereocilium organization
positive regulation of canonical Wnt signaling pathway
monoatomic anion transmembrane transporter activity
solute:inorganic anion antiporter activity
regulation of G protein-coupled receptor signaling pathway
NADH dehydrogenase (ubiquinone) activity
regulation of nitrogen compound metabolic process
RNA polymerase II transcription regulatory region sequence-specific DNA binding
cyclin-dependent protein serine/threonine kinase activator activity
embryonic retina morphogenesis in camera-type eye
fatty acid beta-oxidation using acyl-CoA oxidase
vacuolar proton-transporting V-type ATPase complex
purine-rich negative regulatory element binding
3-hydroxyacyl-CoA dehydrogenase activity
mitochondrial fatty acid beta-oxidation multienzyme complex
negative regulation of Wnt signaling pathway
G protein-coupled receptor kinase activity
SRP-dependent cotranslational protein targeting to membrane
fructose 2,6-bisphosphate metabolic process
regulation of actin filament polymerization
DNA-(apurinic or apyrimidinic site) endonuclease activity
class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G-protein activated inward rectifier potassium channel activity
riboflavin transmembrane transporter activity
G protein-coupled acetylcholine receptor activity
superoxide-generating NADPH oxidase activator activity
anaphase-promoting complex-dependent catabolic process
transmembrane monodehydroascorbate reductase activity
glial cell-derived neurotrophic factor receptor binding
metal ion transmembrane transporter activity
positive regulation of triglyceride catabolic process
glutaminyl-peptide cyclotransferase activity
3-oxoacyl-[acyl-carrier-protein] synthase activity
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
acetyl-CoA transmembrane transporter activity
central nervous system neuron axonogenesis
negative regulation of BMP signaling pathway
vesicle tethering involved in exocytosis
regulatory ncRNA-mediated gene silencing
CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity
double-strand break repair via nonhomologous end joining
long-chain fatty acid-CoA ligase activity
regulation of microtubule cytoskeleton organization
mitochondrial respiratory chain complex IV
tRNA-uridine aminocarboxypropyltransferase activity
ribose phosphate diphosphokinase activity
mitochondrial respiratory chain complex I
glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
glycerol-3-phosphate dehydrogenase complex
oligopeptide transmembrane transporter activity
multi-ciliated epithelial cell differentiation
L-lysine catabolic process to acetyl-CoA via saccharopine
dihydrolipoyllysine-residue succinyltransferase activity
ventral spinal cord interneuron differentiation
glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex
regulation of small GTPase mediated signal transduction
transmembrane receptor protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase signaling pathway
nucleoside triphosphate biosynthetic process
7,8-dihydroneopterin 3'-triphosphate biosynthetic process
tetrahydrobiopterin biosynthetic process
defense response to Gram-negative bacterium
glutamate dehydrogenase [NAD(P)+] activity
oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
proton-transporting V-type ATPase, V0 domain
S-adenosylmethionine biosynthetic process
oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
chloride:monoatomic cation symporter activity
hydroxyacylglutathione hydrolase activity
methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione
alcohol-forming very long-chain fatty acyl-CoA reductase activity
negative regulation of cell differentiation
positive regulation of cell population proliferation
negative regulation of ERK1 and ERK2 cascade
negative regulation of endodermal cell differentiation
negative regulation of fibroblast growth factor receptor signaling pathway
protein folding in endoplasmic reticulum
Adenosine 3',5'-phosphate biosynthetic process
Adenosine-3',5'-cyclic-monophosphate anabolism
Adenosine-3',5'-cyclic-monophosphate biosynthesis
Adenosine-3',5'-cyclic-monophosphate biosynthetic process
Adenosine-3',5'-cyclic-monophosphate formation
Adenosine-3',5'-cyclic-monophosphate synthesis
Cyclic adenylic acid biosynthetic process
inorganic phosphate transmembrane transporter activity
mitochondrial phosphate ion transmembrane transport
bis(5'-adenosyl)-triphosphatase activity
establishment of epithelial cell apical/basal polarity
optic cup morphogenesis involved in camera-type eye development
tumor necrosis factor-mediated signaling pathway
adenylate cyclase-inhibiting dopamine receptor signaling pathway
dopamine neurotransmitter receptor activity
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
mitochondrial electron transport, cytochrome c to oxygen
nuclear-transcribed mRNA poly(A) tail shortening
positive regulation of cytoplasmic mRNA processing body assembly
protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
vacuolar proton-transporting V-type ATPase complex assembly
signal transduction by p53 class mediator
methylenetetrahydrofolate reductase (NAD(P)H) activity
positive regulation of mitochondrial fission
positive regulation of protein targeting to membrane
carbohydrate derivative metabolic process
cardioblast migration to the midline involved in heart field formation
convergent extension involved in nephron morphogenesis
lens placode formation involved in camera-type eye formation
neural plate anterior/posterior regionalization
positive regulation of transcription by RNA polymerase II
regulation of proteasomal ubiquitin-dependent protein catabolic process
collagen-activated tyrosine kinase receptor signaling pathway
regulation of response to external stimulus
mitotic spindle assembly checkpoint signaling
spinal cord motor neuron cell fate specification
obsolete neurotransmitter biosynthetic process
monoatomic ion transmembrane transporter activity
nuclear origin of replication recognition complex
convergent extension involved in organogenesis
G protein-coupled glutamate receptor signaling pathway
transmembrane receptor protein serine/threonine kinase activity
macrophage activation involved in immune response
negative regulation of neutrophil differentiation
farnesyl diphosphate biosynthetic process, mevalonate pathway
hydroxymethylglutaryl-CoA synthase activity
endoplasmic reticulum-plasma membrane tethering
posterior lateral line neuromast primordium migration
potassium ion import across plasma membrane
alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity
protein-malonyllysine demalonylase activity
protein-succinyllysine desuccinylase activity
vascular endothelial growth factor receptor activity
negative regulation of T cell activation
2-octaprenyl-6-methoxy-1,4-benzoquinone methylase activity
2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity
N,N-dimethylaniline monooxygenase activity
tRNA splicing, via endonucleolytic cleavage and ligation
bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity
bis(5'-nucleosyl)-tetraphosphatase activity
Cyclic guanylic acid biosynthetic process
Guanosine 3',5'-phosphate biosynthetic process
Guanosine-3',5'-cyclic-monophosphate anabolism
Guanosine-3',5'-cyclic-monophosphate biosynthesis
Guanosine-3',5'-cyclic-monophosphate biosynthetic process
Guanosine-3',5'-cyclic-monophosphate formation
Guanosine-3',5'-cyclic-monophosphate synthesis
anterior/posterior pattern specification
positive regulation of canonical NF-kappaB signal transduction
nucleobase-containing compound metabolic process
mitotic intra-S DNA damage checkpoint signaling
regulation of cell proliferation involved in compound eye morphogenesis
regulation of photoreceptor cell differentiation
regulation of retina development in camera-type eye
protein-glutamine gamma-glutamyltransferase activity
determination of heart left/right asymmetry
protein serine/threonine/tyrosine kinase activity
glutamate-5-semialdehyde dehydrogenase activity
RNA polymerase II CTD heptapeptide repeat phosphatase activity
hematopoietic progenitor cell differentiation
protein-lysine N-methyltransferase activity
3-oxo-5-alpha-steroid 4-dehydrogenase activity
positive regulation of Rho protein signal transduction
clustering of voltage-gated sodium channels
carnitine O-palmitoyltransferase activity
peptide alpha-N-acetyltransferase activity
uridine transmembrane transporter activity
vasoactive intestinal polypeptide receptor activity
G protein-coupled adenosine receptor activity
ATP-dependent H2AZ histone chaperone activity
calmodulin-dependent protein phosphatase activity
protein-cysteine S-palmitoyltransferase activity
negative regulation of canonical Wnt signaling pathway
positive regulation of translational elongation
positive regulation of translational termination
17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity
17-alpha-hydroxyprogesterone aldolase activity
androst-4-ene-3,17-dione biosynthetic process
negative regulation of insulin receptor signaling pathway
regulation of cell population proliferation
regulation of mitochondrial membrane potential
1,4-alpha-oligoglucan phosphorylase activity
pyrimidine-nucleoside phosphorylase activity
fibroblast growth factor receptor signaling pathway involved in forebrain neuron fate commitment
glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
glutaminyl-tRNAGln biosynthesis via transamidation
glutamyl-tRNA(Gln) amidotransferase complex
diacylglycerol-dependent serine/threonine kinase activity
L-ascorbic acid transmembrane transporter activity
DNA replication preinitiation complex assembly
regulation of DNA-templated DNA replication initiation
diacylglycerol O-acyltransferase activity
telomere maintenance via telomere lengthening
RNA polymerase I core promoter sequence-specific DNA binding
regulation of reactive oxygen species metabolic process
negative regulation of meiotic nuclear division
glycoprotein 6-alpha-L-fucosyltransferase activity
negative regulation of Notch signaling pathway
double-stranded RNA adenosine deaminase activity
regulation of microtubule polymerization or depolymerization
lymphoid lineage cell migration into thymus
RNA N6-methyladenosine methyltransferase complex
phosphatidylethanolamine biosynthetic process
phosphatidylserine decarboxylase activity
thioredoxin-dependent peroxiredoxin activity
galactosylceramide sulfotransferase activity
positive regulation of response to external stimulus
cellular nitrogen compound metabolic process
vitamin transmembrane transporter activity
intermediate filament cytoskeleton organization
establishment or maintenance of cell polarity
positive regulation of cellular component organization
mitochondrial cytochrome c oxidase assembly
negative regulation of endodermal cell fate specification
termination of RNA polymerase II transcription
positive regulation of neural retina development
vacuolar proton-transporting V-type ATPase, V1 domain
choline-phosphate cytidylyltransferase activity
G protein-coupled GABA receptor activity
dolichol-linked oligosaccharide biosynthetic process
dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity
detection of mechanical stimulus involved in sensory perception of touch
endoplasmic reticulum-Golgi intermediate compartment
xenobiotic detoxification by transmembrane export across the plasma membrane
xenobiotic transmembrane transporter activity
cilium movement involved in cell motility
Notch signaling pathway involved in arterial endothelial cell fate commitment
galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity
transforming growth factor beta receptor activity, type II
pyrimidine nucleotide-sugar transmembrane transporter activity
endoplasmic reticulum signal peptide binding
signal recognition particle, endoplasmic reticulum targeting
nicotinamide-nucleotide adenylyltransferase activity
nicotinate-nucleotide adenylyltransferase activity
positive regulation of histone H3-K9 dimethylation
ventral spinal cord interneuron specification
DNA replication-dependent chromatin assembly
transcription cis-regulatory region binding
macrophage colony-stimulating factor receptor binding
positive regulation of protein phosphorylation
ATP synthesis coupled electron transport
negative regulation of biosynthetic process
Ric1-Rgp1 guanyl-nucleotide exchange factor complex
negative regulation of transforming growth factor beta receptor signaling pathway
photoreceptor cell outer segment organization
inositol monophosphate 1-phosphatase activity
inositol monophosphate 3-phosphatase activity
inositol monophosphate 4-phosphatase activity
phosphatidylinositol phosphate biosynthetic process
beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity
nucleoside triphosphate adenylate kinase activity
protein-phosphatidylethanolamide deconjugating activity
late distal convoluted tubule development
thioredoxin-disulfide reductase (NADP) activity
3-demethoxyubiquinol 3-hydroxylase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
determination of pancreatic left/right asymmetry
regulation of plasma membrane sterol distribution
ubiquitin-dependent protein catabolic process via the N-end rule pathway
'de novo' NAD biosynthetic process from tryptophan
3-hydroxyanthranilate 3,4-dioxygenase activity
positive regulation of DNA demethylation
establishment of mitotic spindle orientation
chaperone cofactor-dependent protein refolding
calcium-dependent cysteine-type endopeptidase activity
gamma-aminobutyric acid:sodium:chloride symporter activity
proton-transporting ATP synthase complex, catalytic core F(1)
L-cystine L-cysteine-lyase (deaminating)
glutathione specific gamma-glutamylcyclotransferase activity
aspartate family amino acid metabolic process
dimethylallyl diphosphate biosynthetic process
isopentenyl-diphosphate delta-isomerase activity
determination of digestive tract left/right asymmetry
determination of left/right asymmetry in diencephalon
embryonic heart tube left/right pattern formation
regulation of convergent extension involved in gastrulation
negative regulation of lymphocyte differentiation
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
receptor signaling protein tyrosine kinase activator activity
positive regulation of transcription initiation by RNA polymerase II
calcium-dependent protein serine/threonine phosphatase regulator activity
transforming growth factor beta receptor binding
sphingosine-1-phosphate receptor activity
GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity
protein serine/threonine kinase inhibitor activity
establishment or maintenance of microtubule cytoskeleton polarity
molybdate ion transmembrane transporter activity
18S rRNA aminocarboxypropyltransferase activity
enzyme-directed rRNA pseudouridine synthesis
mitochondrial electron transport, NADH to ubiquinone
positive regulation of double-strand break repair
acetyl-CoA biosynthetic process from pyruvate
pyruvate dehydrogenase (acetyl-transferring) activity
aspartic endopeptidase activity, intramembrane cleaving
mitochondrial ADP transmembrane transport
mitochondrial ATP transmembrane transport
tRNA-type intron splice site recognition and cleavage
negative regulation of protein phosphorylation
diphosphomevalonate decarboxylase activity
isopentenyl diphosphate biosynthetic process, mevalonate pathway
regulation of mitotic cell cycle spindle assembly checkpoint
determination of liver left/right asymmetry
NMDA selective glutamate receptor complex
poly(ADP-ribose) glycohydrolase activity
RNA polymerase II C-terminal domain binding
RNA polymerase II CTD heptapeptide repeat kinase activity
10-formyltetrahydrofolate catabolic process
formyltetrahydrofolate dehydrogenase activity
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
sphingolipid delta-4 desaturase activity
protein-L-isoaspartate (D-aspartate) O-methyltransferase activity
L-tyrosine:2-oxoglutarate aminotransferase activity
cAMP response element binding protein binding
TRIF-dependent toll-like receptor signaling pathway
transcription elongation factor activity
ATPase-coupled intramembrane lipid transporter activity
tryptophan catabolic process to kynurenine
3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
cis-regulatory region sequence-specific DNA binding
double-strand break repair via single-strand annealing
nucleoside transmembrane transporter activity
K63-linked polyubiquitin modification-dependent protein binding
midbrain-hindbrain boundary morphogenesis
regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation
positive regulation of centrosome duplication
regulation of actin cytoskeleton organization
embryonic cranial skeleton morphogenesis
negative regulation of histone methylation
positive regulation of histone acetylation
glycine biosynthetic process from serine
glycine hydroxymethyltransferase activity
tRNA aminoacylation for protein translation
3-hydroxy-4-(trimethylammonio)butanoate anabolism
3-hydroxy-4-(trimethylammonio)butanoate biosynthesis
3-hydroxy-4-(trimethylammonio)butanoate biosynthetic process
3-hydroxy-4-(trimethylammonio)butanoate formation
3-hydroxy-4-(trimethylammonio)butanoate synthesis
Gamma-trimethyl-hydroxybutyrobetaine anabolism
Gamma-trimethyl-hydroxybutyrobetaine biosynthesis
Gamma-trimethyl-hydroxybutyrobetaine biosynthetic process
Gamma-trimethyl-hydroxybutyrobetaine formation
Gamma-trimethyl-hydroxybutyrobetaine synthesis
sulfate adenylyltransferase (ATP) activity
histone H4K20 methyltransferase activity
histone H4K20 monomethyltransferase activity
transcription preinitiation complex assembly
mitochondrial proton-transporting ATP synthase complex
blood vessel endothelial cell differentiation
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
regulation of axon extension involved in axon guidance
glycylpeptide N-tetradecanoyltransferase activity
protein O-acetylglucosaminyltransferase activity
tRNA wobble adenosine to inosine editing
tRNA-specific adenosine deaminase activity
tRNA-specific adenosine-34 deaminase activity
obsolete acyl-coenzyme A diphosphatase activity
negative regulation of mRNA polyadenylation
retinol transmembrane transporter activity
cellular response to amino acid stimulus
regulation of hemoglobin biosynthetic process
protein-tyrosine sulfotransferase activity
protein-N-terminal asparagine amidohydrolase activity
mannose-1-phosphate guanylyltransferase (GTP) activity
negative regulation of vasculature development
regulation of vascular endothelial growth factor receptor signaling pathway
endoplasmic reticulum tubular network formation
obsolete tRNA (guanine-N2-)-methyltransferase activity
positive regulation of acrosome reaction
DNA polymerase processivity factor activity
[heparan sulfate]-glucosamine N-sulfotransferase activity
heparan sulfate proteoglycan biosynthetic process
secondary active sulfate transmembrane transporter activity
proteasome regulatory particle, base subcomplex
tRNA (cytidine-5-)-methyltransferase activity
anterior/posterior pattern specification involved in pronephros development
tRNA uridine(34) acetyltransferase activity
obsolete nucleic acid phosphodiester bond hydrolysis
camera-type eye photoreceptor cell development
positive regulation of cell migration involved in sprouting angiogenesis
positive regulation of filopodium assembly
regulation of systemic arterial blood pressure by renin-angiotensin
carbohydrate transmembrane transporter activity
Proton-transporting ATP synthase complex catalytic core F(1)
mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)
Mo-molybdopterin cofactor sulfurase activity
phosphatidylinositol-3,4,5-trisphosphate binding
1-alkyl-2-acetylglycerophosphocholine esterase activity
aminoacyl-tRNA synthetase multienzyme complex
growth hormone-releasing hormone activity
initiator methionyl aminopeptidase activity
1-phosphatidylinositol-3-kinase activity
FAD-dependent H3K4me/H3K4me3 demethylase activity
ubiquitin-like modifier activating enzyme activity
proteasome core complex, beta-subunit complex
peroxisome matrix targeting signal-2 binding
water transmembrane transporter activity
O-phosphoseryl-tRNA(Sec) selenium transferase activity
conversion of seryl-tRNAsec to selenocys-tRNAsec
single-stranded DNA 5'-3' DNA exonuclease activity
nucleobase-containing compound kinase activity
positive regulation of hypoxia-inducible factor-1alpha signaling pathway
positive regulation of protein sumoylation
DNA-binding transcription factor binding
positive regulation of BMP signaling pathway
biotin-[acetyl-CoA-carboxylase] ligase activity
regulation of establishment of cell polarity
UDP-glucose:hexose-1-phosphate uridylyltransferase activity
galactose catabolic process via UDP-galactose
calcium-activated potassium channel activity
formimidoyltetrahydrofolate cyclodeaminase activity
glutamate formimidoyltransferase activity
histidine catabolic process to glutamate and formamide
histidine catabolic process to glutamate and formate
blood vessel endothelial cell proliferation involved in sprouting angiogenesis
branching involved in blood vessel morphogenesis
adenyl-nucleotide exchange factor activity
mitochondrial pyruvate transmembrane transport
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
negative regulation of retinal cell programmed cell death
intestinal epithelial cell differentiation
oxidative single-stranded RNA demethylation
ATP-dependent NAD(P)H-hydrate dehydratase activity
nicotinamide nucleotide metabolic process
attachment of mitotic spindle microtubules to kinetochore
succinate-CoA ligase (ADP-forming) activity
regulation of stem cell population maintenance
1-acylglycerophosphocholine O-acyltransferase activity
gastric inhibitory peptide receptor activity
cysteine-type endopeptidase inhibitor activity
rRNA (guanine) methyltransferase activity
collagen-containing extracellular matrix
cytochrome-b5 reductase activity, acting on NAD(P)H
tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent
organonitrogen compound metabolic process
magnesium ion transmembrane transporter activity
RNA polymerase II-specific DNA-binding transcription factor binding
protein maturation by [4Fe-4S] cluster transfer
regulation of ceramide biosynthetic process
fructose-2,6-bisphosphate 2-phosphatase activity
DNA topoisomerase type I (single strand cut, ATP-independent) activity
N6-methyladenosine-containing RNA reader activity
positive regulation of SREBP signaling pathway
angioblast cell migration from lateral mesoderm to midline
arterial endothelial cell fate commitment
ciliary receptor clustering involved in smoothened signaling pathway
forebrain dorsal/ventral pattern formation
positive regulation of smoothened signaling pathway
vitamin-K-epoxide reductase (warfarin-sensitive) activity
2-(3-amino-3-carboxypropyl)histidine synthase activity
multicellular organismal response to stress
G protein-coupled opioid receptor activity
3-beta-hydroxy-delta5-steroid dehydrogenase activity
ATP-activated inward rectifier potassium channel activity
glycine dehydrogenase (decarboxylating) activity
phosphoribosylformylglycinamidine synthase activity
pentose-phosphate shunt, non-oxidative branch
regulation of Wnt signaling pathway involved in heart development
phosphatidylcholine-retinol O-acyltransferase activity
endoribonuclease activity, cleaving siRNA-paired mRNA
miRNA-mediated gene silencing by inhibition of translation
miRNA-mediated gene silencing by mRNA destabilization
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity
mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
trans-L-3-hydroxyproline dehydratase activity
4-alpha-hydroxytetrahydrobiopterin dehydratase activity
histone H3K27 methyltransferase activity
negative regulation of activin receptor signaling pathway
P-type transmembrane transporter activity
molybdopterin adenylyltransferase activity
molybdopterin molybdotransferase activity
protein carboxyl O-methyltransferase activity
G protein-coupled neurotensin receptor activity
inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
positive regulation of transcription of Notch receptor target
oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
phosphatidate cytidylyltransferase activity
mannose-ethanolamine phosphotransferase activity
P450-containing electron transport chain
clathrin coat of trans-Golgi network vesicle
inorganic diphosphate phosphatase activity
phosphate-containing compound metabolic process
glycine betaine biosynthetic process from choline
ubiquitin-like protein transferase activity
regulation of Rho protein signal transduction
flavin-dependent sulfhydryl oxidase activity
ribosomal large subunit export from nucleus
ribosomal small subunit export from nucleus
fructose 1,6-bisphosphate 1-phosphatase activity
thiamine triphosphate phosphatase activity
negative regulation of mitotic cell cycle
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity
phosphatidylinositol-3-phosphate phosphatase activity
vascular endothelial growth factor receptor signaling pathway
complement activation, classical pathway
single-stranded DNA exodeoxyribonuclease activity
atrial cardiac muscle cell differentiation
tetrahydrofolylpolyglutamate synthase activity
Golgi to plasma membrane protein transport
transmembrane ascorbate ferrireductase activity
ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity
ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity
negative regulation of neuron apoptotic process
procollagen-lysine 5-dioxygenase activity
voltage-gated monoatomic anion channel activity
thyrotropin-releasing hormone receptor activity
'de novo' pyrimidine nucleobase biosynthetic process
glutathione dehydrogenase (ascorbate) activity
malate dehydrogenase (decarboxylating) (NAD+) activity
actin polymerization or depolymerization
positive regulation of neutrophil migration
oxoglutarate dehydrogenase (succinyl-transferring) activity
ciliary neurotrophic factor receptor binding
ciliary neurotrophic factor-mediated signaling pathway
cAMP-dependent protein kinase inhibitor activity
protoheme IX farnesyltransferase activity
L-aspartate:2-oxoglutarate aminotransferase activity
pigment granule aggregation in cell center
branched-chain amino acid catabolic process
branched-chain amino acid transmembrane transporter activity
hydrolase activity, hydrolyzing N-glycosyl compounds
G protein-coupled glutamate receptor binding
adenylate cyclase-activating G protein-coupled receptor signaling pathway
regulation of osteoblast differentiation
proteasome regulatory particle, lid subcomplex
5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity
dystrophin-associated glycoprotein complex
histone H3K27 trimethyltransferase activity
intracellular non-membrane-bounded organelle
phosphatidylinositol N-acetylglucosaminyltransferase activity
negative regulation of substrate adhesion-dependent cell spreading
regulation of Arp2/3 complex-mediated actin nucleation
vesicle targeting, trans-Golgi to endosome
low-density lipoprotein particle receptor binding
8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity
purine deoxyribonucleotide metabolic process
hindbrain-spinal cord boundary formation
protein serine/threonine phosphatase inhibitor activity
oxidoreductase activity, acting on the CH-CH group of donors
very-long-chain enoyl-CoA reductase activity
G protein-coupled peptide receptor activity
tRNA (uridine) methyltransferase activity
long-chain fatty acid import into peroxisome
long-chain fatty acid transporter activity
regulation of retinoic acid receptor signaling pathway
detection of light stimulus involved in visual perception
positive regulation of interleukin-1 production
endoplasmic reticulum tubular network maintenance
endoplasmic reticulum tubular network membrane
positive regulation of endoplasmic reticulum tubular network organization
MAP kinase kinase kinase kinase activity
phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity
positive regulation of developmental process
sequence-specific double-stranded DNA binding
calcium-activated cation channel activity
Rab-protein geranylgeranyltransferase complex
L-methionine-(R)-S-oxide reductase activity
peptide-methionine (R)-S-oxide reductase activity
positive regulation of Wnt signaling pathway
positive regulation of somitomeric trunk muscle development
ventricular cardiac muscle cell differentiation
protein serine/threonine kinase activator activity
cyclin-dependent protein serine/threonine kinase activity
N-acylphosphatidylethanolamine-specific phospholipase D activity
establishment of endothelial blood-brain barrier
posterior lateral line neuromast deposition
RNA polymerase II general transcription initiation factor binding
regulation of mitotic metaphase/anaphase transition
ribosome-associated ubiquitin-dependent protein catabolic process
estradiol 17-beta-dehydrogenase [NAD(P)] activity
ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
endoplasmic reticulum unfolded protein response
heparan sulfate sulfotransferase activity
regulation of canonical Wnt signaling pathway
regulation of cell-cell adhesion mediated by cadherin
GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity
GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase activity
determination of left/right asymmetry in lateral mesoderm
protein-L-histidine N-pros-methyltransferase activity
lymphatic endothelial cell fate commitment
5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase activity
positive regulation of convergent extension involved in gastrulation
positive regulation of non-canonical Wnt signaling pathway
zinc ion transmembrane transporter activity
cellular response to 2,3,7,8-tetrachlorodibenzodioxine
regulation of cardiac muscle contraction
fibroblast growth factor receptor activity
regulation of chondrocyte differentiation
G protein-coupled acetylcholine receptor signaling pathway
2-iminobutanoate/2-iminopropanoate deaminase
detection of stimulus involved in sensory perception
methylated-DNA-[protein]-cysteine S-methyltransferase activity
positive regulation of heart contraction
CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity
tRNA-guanosine(34) queuine transglycosylase activity
N-acetyl-beta-D-galactosaminidase activity
thyroid-stimulating hormone receptor activity
regulation of mitochondrial mRNA stability
crossover junction DNA endonuclease activity
double-strand break repair via break-induced replication
positive regulation of actin filament polymerization
negative regulation of protein secretion
regulation of epidermal growth factor receptor signaling pathway
late endosome to vacuole transport via multivesicular body sorting pathway
positive regulation of protein dephosphorylation
medium-chain-acyl-CoA dehydrogenase activity
histone H3K36 methyltransferase activity
glucose 6-phosphate:inorganic phosphate antiporter activity
nucleoside diphosphate phosphatase activity
regulation of complement activation, lectin pathway
dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity
regulation of glutamate receptor signaling pathway
polyubiquitin modification-dependent protein binding
cortical actin cytoskeleton organization
mitochondrial oxoglutarate dehydrogenase complex
regulation of cell cycle G2/M phase transition
deadenylation-independent decapping of nuclear-transcribed mRNA
electron-transferring-flavoprotein dehydrogenase activity
NAD+ nucleotidase, cyclic ADP-ribose generating
negative regulation of MyD88-independent toll-like receptor signaling pathway
H4/H2A histone acetyltransferase complex
2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity
2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity
endothelial tip cell filopodium assembly
regulation of cell migration involved in sprouting angiogenesis
2,4-dienoyl-CoA reductase (NADPH) activity
eukaryotic translation elongation factor 1 complex
mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity
protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
positive regulation of transcription elongation by RNA polymerase II
cytoskeleton-dependent intracellular transport
skeletal muscle satellite cell migration
N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity
glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity
nucleoside triphosphate diphosphatase activity
5-phosphoribose 1-diphosphate biosynthetic process
ribonucleoside monophosphate biosynthetic process
deoxyribonucleoside triphosphate catabolic process
regulation of cellular response to insulin stimulus
regulation of ER-associated ubiquitin-dependent protein catabolic process
cell migration involved in mesendoderm migration
mesoderm migration involved in gastrulation
pyrimidine nucleotide biosynthetic process
regulation of DNA-templated transcription elongation
transcription elongation-coupled chromatin remodeling
regulation of calcineurin-mediated signaling
regulation of cardiac muscle hypertrophy
central nervous system neuron development
peripheral nervous system neuron development
regulation of toll-like receptor signaling pathway
meiotic nuclear membrane microtubule tethering complex
Deoxyribonucleotide biosynthetic process
ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
tRNA threonylcarbamoyladenosine modification
cellular response to prostaglandin stimulus
cellular response to xenobiotic stimulus
regulation of mitotic cell cycle, embryonic
regulation of neurotransmitter secretion
holo-[acyl-carrier-protein] synthase activity
ubiquinol-cytochrome-c reductase activity
2',3'-cyclic-nucleotide 3'-phosphodiesterase activity
mitochondrial respiratory chain complex II assembly
establishment of mitotic spindle localization
regulation of retinal ganglion cell axon guidance
asparagine synthase (glutamine-hydrolyzing) activity
establishment of protein localization to membrane
obsolete tRNA (guanine-N1-)-methyltransferase activity
MyD88-dependent toll-like receptor signaling pathway
aminocarboxymuconate-semialdehyde decarboxylase activity
negative regulation of quinolinate biosynthetic process
melanin-concentrating hormone receptor activity
regulation of double-strand break repair via homologous recombination
3,4-dihydroxy-5-polyprenylbenzoic acid O-methyltransferase activity
3-demethylubiquinol-n 3-O-methyltransferase activity
ATP-binding cassette (ABC) transporter complex
6-pyruvoyltetrahydropterin synthase activity
negative regulation of translational elongation
dolichyl-phosphate beta-D-mannosyltransferase activity
'de novo' cotranslational protein folding
proton-transporting two-sector ATPase complex, catalytic domain
UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity
histone H3K9 trimethyltransferase activity
protein-N-terminal glutamine amidohydrolase activity
S-(hydroxymethyl)glutathione dehydrogenase NAD activity
S-(hydroxymethyl)glutathione dehydrogenase NADP activity
S-(hydroxymethyl)glutathione dehydrogenase activity
4-hydroxyphenylpyruvate dioxygenase activity
regulation of macrophage differentiation
regulation of neutrophil differentiation
transmitter-gated monoatomic ion channel activity
regulation of mRNA cis splicing, via spliceosome
deoxyribonucleoside 5'-monophosphate N-glycosidase activity
deoxyribonucleoside monophosphate catabolic process
acetylcholine receptor regulator activity
K48-linked polyubiquitin modification-dependent protein binding
oxidoreductase activity, acting on NAD(P)H
N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity
rRNA (pseudouridine) methyltransferase activity
iron ion transmembrane transporter activity
mitotic recombination-dependent replication fork processing
extracellular matrix constituent secretion
1,4-alpha-glucan branching enzyme activity
protein import into mitochondrial intermembrane space
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
centrosome-templated microtubule nucleation
negative regulation of phosphate metabolic process
negative regulation of protein modification process
positive regulation of release of cytochrome c from mitochondria
oxidative single-stranded DNA demethylation
selenocysteine insertion sequence binding
ornithine decarboxylase inhibitor activity
antigen processing and presentation of endogenous peptide antigen via MHC class I
1-phosphatidylinositol-3-kinase regulator activity
phosphatidylinositol 3-kinase complex, class IB
delta4-3-oxosteroid 5beta-reductase activity
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
negative regulation of gene expression, epigenetic
regulation of non-canonical NF-kappaB signal transduction
positive regulation of DNA damage response, signal transduction by p53 class mediator
heparosan-N-sulfate-glucuronate 5-epimerase activity
rRNA (uridine-N3-)-methyltransferase activity
mitotic DNA replication checkpoint signaling
exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)