Ubiquitin-like modifier conjugation pathway
ubiquitin-dependent protein catabolic process
galactosylceramide sulfotransferase activity
extracellular ligand-gated monoatomic ion channel activity
transmembrane signaling receptor activity
regulation of monoatomic ion transmembrane transport
voltage-gated potassium channel activity
regulation of DNA-templated transcription
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity
proteasome-mediated ubiquitin-dependent protein catabolic process
DNA-binding transcription factor activity
regulation of transcription by RNA polymerase II
homophilic cell adhesion via plasma membrane adhesion molecules
regulation of complement activation, lectin pathway
DNA-binding transcription factor activity, RNA polymerase II-specific
positive regulation of DNA-templated transcription
Nicotinamide adenine dinucleotide phosphate
Nicotinic adenine dinucleotide phosphate
N,N-dimethylaniline monooxygenase activity
S-adenosylmethionine-dependent methyltransferase activity
RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA-binding transcription activator activity, RNA polymerase II-specific
hydrolase activity, hydrolyzing O-glycosyl compounds
pyrimidine nucleotide-sugar transmembrane transporter activity
inositol pentakisphosphate 2-kinase activity
monoatomic anion transmembrane transporter activity
protein serine/threonine kinase activity
alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity
sphingomyelin phosphodiesterase activity
positive regulation of transcription by RNA polymerase II
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
G protein-coupled serotonin receptor activity
phosphotransferase activity, alcohol group as acceptor
mitochondrial cytochrome c oxidase assembly
phosphatidylinositol-3-phosphate binding
nucleobase-containing compound metabolic process
acetylcholine-gated monoatomic cation-selective channel activity
small GTPase mediated signal transduction
protein-arginine N-methyltransferase activity
very long-chain fatty acid biosynthetic process
[protein-PII] uridylyltransferase activity
ATP-dependent diacylglycerol kinase activity
protein kinase C-activating G protein-coupled receptor signaling pathway
calcium-activated cation channel activity
protein modification by small protein conjugation
ubiquitin-like modifier activating enzyme activity
nicotinate-nucleotide diphosphorylase (carboxylating) activity
G protein-coupled receptor signaling pathway
nucleoside diphosphate phosphatase activity
phosphatidylinositol-3,5-bisphosphate binding
minus-end-directed microtubule motor activity
mitotic G2 DNA damage checkpoint signaling
polyubiquitin modification-dependent protein binding
positive regulation of SREBP signaling pathway
sphingosine-1-phosphate phosphatase activity
double-strand break repair via nonhomologous end joining
acyltransferase activity, transferring groups other than amino-acyl groups
eukaryotic translation elongation factor 1 complex
positive regulation of interleukin-1 production
mitochondrial respiratory chain complex I
adenylate cyclase-activating G protein-coupled receptor signaling pathway
long-chain fatty acid import into peroxisome
long-chain fatty acid transporter activity
calcium-dependent cysteine-type endopeptidase activity
tRNA (uridine) methyltransferase activity
positive regulation of transcription of Notch receptor target
negative regulation of apoptotic process
phosphatidylinositol-4-phosphate binding
positive regulation of translational elongation
positive regulation of translational termination
positive regulation of transcription initiation by RNA polymerase II
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
inositol monophosphate 1-phosphatase activity
phosphatidylinositol phosphate biosynthetic process
guanyl-nucleotide exchange factor activity
proton-transporting ATPase activity, rotational mechanism
vacuolar proton-transporting V-type ATPase, V1 domain
proteasome core complex, beta-subunit complex
ATP-dependent DNA damage sensor activity
double-strand break repair via homologous recombination
ammonium transmembrane transporter activity
negative regulation of signal transduction
cyclin-dependent protein serine/threonine kinase activator activity
protoheme IX farnesyltransferase activity
mitochondrial electron transport, NADH to ubiquinone
extrinsic component of mitochondrial inner membrane
tetrahydrobiopterin biosynthetic process
outward rectifier potassium channel activity
calcium ion-regulated exocytosis of neurotransmitter
regulation of calcium ion-dependent exocytosis
carbohydrate derivative metabolic process
UDP-N-acetylglucosamine biosynthetic process
phosphoacetylglucosamine mutase activity
negative regulation of canonical Wnt signaling pathway
ligand-gated monoatomic ion channel activity
protein-lysine N-methyltransferase activity
extracellular matrix structural constituent
histone H2AQ104 methyltransferase activity
anterior/posterior pattern specification
Adenosine 5'-triphosphate biosynthetic process
Adenosine triphosphate biosynthetic process
Proton-transporting ATP synthase complex coupling factor F(0)
mitochondrial proton-transporting ATP synthase complex
proton motive force-driven ATP synthesis
proton transmembrane transporter activity
proton-transporting ATP synthase complex, coupling factor F(o)
tRNA splicing, via endonucleolytic cleavage and ligation
endoplasmic reticulum-plasma membrane tethering
thiamine diphosphate biosynthetic process
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
N-acylsphingosine amidohydrolase activity
phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity
regulation of cilium beat frequency involved in ciliary motility
intracellular membrane-bounded organelle
peptidyl-prolyl cis-trans isomerase activity
histone H3K36 methyltransferase activity
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
Arp2/3 complex-mediated actin nucleation
N-acetylmuramoyl-L-alanine amidase activity
regulation of cell population proliferation
regulation of small GTPase mediated signal transduction
positive regulation of transcription elongation by RNA polymerase II
positive regulation of canonical NF-kappaB signal transduction
cytochrome-b5 reductase activity, acting on NAD(P)H
DNA-directed 5'-3' RNA polymerase activity
maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II
transcription initiation at RNA polymerase II promoter
transcription-coupled nucleotide-excision repair
cysteine-type endopeptidase activity involved in execution phase of apoptosis
recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex
transcription elongation by RNA polymerase II
chloride transmembrane transporter activity
negative regulation of transcription by RNA polymerase II
Glycosylphosphatidylinositol anchor anabolism
Glycosylphosphatidylinositol anchor biosynthesis
Glycosylphosphatidylinositol anchor biosynthetic process
Glycosylphosphatidylinositol anchor formation
Glycosylphosphatidylinositol anchor synthesis
'de novo' pyrimidine nucleobase biosynthetic process
SRP-dependent cotranslational protein targeting to membrane
negative regulation of translational elongation
signal recognition particle, endoplasmic reticulum targeting
dihydrolipoyllysine-residue succinyltransferase activity
fructose 2,6-bisphosphate metabolic process
fructose-2,6-bisphosphate 2-phosphatase activity
regulation of nitrogen compound metabolic process
tryptophan catabolic process to kynurenine
ribosomal large subunit export from nucleus
fatty acid elongation, monounsaturated fatty acid
fatty acid elongation, polyunsaturated fatty acid
fatty acid elongation, saturated fatty acid
Deoxyribonucleotide biosynthetic process
RNA polymerase II preinitiation complex assembly
metal ion transmembrane transporter activity
gamma-glutamylaminecyclotransferase activity
endoplasmic reticulum to Golgi vesicle-mediated transport
oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
negative regulation of BMP signaling pathway
protoporphyrinogen IX biosynthetic process
obsolete tRNA (guanine-N1-)-methyltransferase activity
mitochondrial ADP transmembrane transport
mitochondrial ATP transmembrane transport
oxoglutarate dehydrogenase (succinyl-transferring) activity
negative regulation of transcription by RNA polymerase III
ubiquitin-protein transferase activator activity
attachment of spindle microtubules to kinetochore
mitotic spindle assembly checkpoint signaling
acyltransferase activity, acyl groups converted into alkyl on transfer
vasoactive intestinal polypeptide receptor activity
hydroxymethylglutaryl-CoA lyase activity
negative regulation of DNA-templated transcription
transmembrane receptor protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase signaling pathway
guanidinoacetate N-methyltransferase activity
hydrolase activity, acting on ester bonds
electron-transferring-flavoprotein dehydrogenase activity
alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity
2-(3-amino-3-carboxypropyl)histidine synthase activity
1-alkyl-2-acetylglycerophosphocholine esterase activity
protein tyrosine/serine/threonine phosphatase activity
RNA polymerase II general transcription initiation factor activity
TFIIF-class transcription factor complex binding
procollagen-proline 4-dioxygenase activity
sulfate adenylyltransferase (ATP) activity
glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group
transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
deoxyribodipyrimidine photo-lyase activity
regulation of alternative mRNA splicing, via spliceosome
glycerol-3-phosphate dehydrogenase complex
obsolete sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity
eukaryotic translation initiation factor 3 complex
eukaryotic translation initiation factor 3 complex, eIF3m
formation of cytoplasmic translation initiation complex
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
ATP-dependent chromatin remodeler activity
negative regulation of biosynthetic process
respiratory gaseous exchange by respiratory system
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
asparagine synthase (glutamine-hydrolyzing) activity
P-type transmembrane transporter activity
protein processing involved in protein targeting to mitochondrion
phosphopantothenoylcysteine decarboxylase activity
phosphopantothenoylcysteine decarboxylase complex
tRNA-uridine aminocarboxypropyltransferase activity
RNA polymerase II CTD heptapeptide repeat kinase activity
cyclin-dependent protein serine/threonine kinase activity
anaphase-promoting complex-dependent catabolic process
regulation of mitotic metaphase/anaphase transition
glutathione dehydrogenase (ascorbate) activity
5-amino-6-(5-phosphoribosylamino)uracil reductase activity
serine-type endopeptidase inhibitor activity
non-membrane spanning protein tyrosine kinase activity
monoatomic cation:bicarbonate symporter activity
zinc ion transmembrane transporter activity
positive regulation of response to external stimulus
transferase activity, transferring phosphorus-containing groups
FAD-dependent H3K4me/H3K4me3 demethylase activity
nuclear-transcribed mRNA catabolic process, no-go decay
nuclear-transcribed mRNA catabolic process, non-stop decay
bis(5'-adenosyl)-triphosphatase activity
L-ascorbic acid transmembrane transporter activity
Molybdenum cofactor biosynthetic process
Mo-molybdopterin cofactor biosynthetic process
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
carbohydrate transmembrane transporter activity
establishment or maintenance of cell polarity
positive regulation of cellular component organization
calmodulin-dependent protein kinase activity
mitochondrial calcium ion transmembrane transport
collagen-containing extracellular matrix
proteasome core complex, alpha-subunit complex
proteolysis involved in protein catabolic process
inward rectifier potassium channel activity
hydrolase activity, acting on acid anhydrides
2-iminobutanoate/2-iminopropanoate deaminase
organonitrogen compound catabolic process
polynucleotide 5'-hydroxyl-kinase activity
P-type potassium transmembrane transporter activity
cellular response to amino acid stimulus
alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity
negative regulation of synaptic vesicle exocytosis
negative regulation of protein ubiquitination
3-beta-hydroxy-delta5-steroid dehydrogenase activity
RNA polymerase II transcription regulatory region sequence-specific DNA binding
alcohol-forming very long-chain fatty acyl-CoA reductase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
G protein-coupled acetylcholine receptor signaling pathway
mRNA regulatory element binding translation repressor activity
negative regulation of translational initiation
cilium movement involved in cell motility
dehydrodolichyl diphosphate synthase activity
dehydrodolichyl diphosphate synthase complex
regulation of G protein-coupled receptor signaling pathway
G protein-coupled receptor kinase activity
dolichol-linked oligosaccharide biosynthetic process
regulatory ncRNA-mediated gene silencing
thioredoxin-disulfide reductase (NADP) activity
negative regulation of DNA recombination
thyrotropin-releasing hormone receptor activity
negative regulation of actin filament polymerization
mitotic DNA replication checkpoint signaling
oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor
intraciliary transport involved in cilium assembly
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
cAMP-dependent protein kinase regulator activity
diacylglycerol-dependent serine/threonine kinase activity
alternative mRNA splicing, via spliceosome
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
regulation of double-strand break repair via homologous recombination
DNA-(apurinic or apyrimidinic site) endonuclease activity
oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity
rRNA (guanine) methyltransferase activity
ribosome-associated ubiquitin-dependent protein catabolic process
oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
ATP synthesis coupled electron transport
NADH dehydrogenase (ubiquinone) activity
glucose-6-phosphate dehydrogenase activity
endoplasmic reticulum tubular network maintenance
endoplasmic reticulum tubular network membrane
positive regulation of endoplasmic reticulum tubular network organization
CAAX-protein geranylgeranyltransferase complex
protein geranylgeranyltransferase activity
voltage-gated monoatomic anion channel activity
Cyclic guanylic acid biosynthetic process
Guanosine 3',5'-phosphate biosynthetic process
Guanosine-3',5'-cyclic-monophosphate anabolism
Guanosine-3',5'-cyclic-monophosphate biosynthesis
Guanosine-3',5'-cyclic-monophosphate biosynthetic process
Guanosine-3',5'-cyclic-monophosphate formation
Guanosine-3',5'-cyclic-monophosphate synthesis
UDP-N-acetylglucosamine metabolic process
phosphatidylcholine transporter activity
calcium-activated potassium channel activity
DNA topoisomerase type I (single strand cut, ATP-independent) activity
acetyl-CoA biosynthetic process from acetate
tRNA (guanine) methyltransferase activity
protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
regulation of Rho protein signal transduction
NAD-dependent protein deacetylase activity
protein-malonyllysine demalonylase activity
protein-succinyllysine desuccinylase activity
copper ion transmembrane transporter activity
formation of translation preinitiation complex
Mo-molybdopterin cofactor sulfurase activity
mitochondrial respiratory chain complex IV
protein-disulfide reductase (NAD(P)) activity
mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
hydrolase activity, hydrolyzing N-glycosyl compounds
positive regulation of protein polymerization
protein serine/threonine phosphatase activity
P450-containing electron transport chain
chaperone-mediated protein complex assembly
NAD-dependent histone deacetylase activity
positive regulation of triglyceride catabolic process
phospholipase C-activating G protein-coupled receptor signaling pathway
ATPase-coupled monoatomic cation transmembrane transporter activity
protein serine/threonine phosphatase inhibitor activity
cyclin-dependent protein serine/threonine kinase inhibitor activity
regulation of macromolecule metabolic process
mitochondria-associated endoplasmic reticulum membrane
mitochondrion-endoplasmic reticulum membrane tethering
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
transmembrane monodehydroascorbate reductase activity
intracellular non-membrane-bounded organelle
3-oxo-5-alpha-steroid 4-dehydrogenase activity
phosphatidylinositol biosynthetic process
methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione
D-arabinono-1,4-lactone oxidase activity
ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity
betaine-homocysteine S-methyltransferase activity
nuclear-transcribed mRNA catabolic process
TIM23 mitochondrial import inner membrane translocase complex
protein import into mitochondrial matrix
negative regulation of Wnt signaling pathway
RNA polymerase II CTD heptapeptide repeat phosphatase activity
L-methionine salvage from S-adenosylmethionine
L-methionine salvage from methylthioadenosine
methylthioribulose 1-phosphate dehydratase activity
non-membrane spanning protein tyrosine phosphatase activity
clathrin coat of trans-Golgi network vesicle
cytoskeleton-dependent intracellular transport
G protein-coupled glutamate receptor signaling pathway
group II metabotropic glutamate receptor activity
regulation of synaptic transmission, glutamatergic
protein-glutamine gamma-glutamyltransferase activity
ornithine decarboxylase inhibitor activity
modification-dependent protein catabolic process
ATPase-coupled intramembrane lipid transporter activity
retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
sugar transmembrane transporter activity
mitochondrial respiratory chain complex III assembly
tRNA (cytidine-3-)-methyltransferase activity
acetylgalactosaminyltransferase activity
nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
polyadenylation-dependent snoRNA 3'-end processing
homologous chromosome pairing at meiosis
3'(2'),5'-bisphosphate nucleotidase activity
solute:inorganic anion antiporter activity
protein transmembrane transporter activity
centrosome-templated microtubule nucleation
crossover junction DNA endonuclease activity
double-strand break repair via break-induced replication
porphyrin-containing compound biosynthetic process
inositol tetrakisphosphate 1-kinase activity
inositol trisphosphate metabolic process
inositol-1,3,4-trisphosphate 5-kinase activity
inositol-1,3,4-trisphosphate 6-kinase activity
mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity
negative regulation of Ras protein signal transduction
negative regulation of fibroblast growth factor receptor signaling pathway
alkylglycerone-phosphate synthase activity
vitamin-K-epoxide reductase (warfarin-sensitive) activity
3-oxoacyl-[acyl-carrier-protein] synthase activity
long-chain-acyl-CoA dehydrogenase activity
biotin-[acetyl-CoA-carboxylase] ligase activity
regulation of ARF protein signal transduction
18S rRNA aminocarboxypropyltransferase activity
enzyme-directed rRNA pseudouridine synthesis
2',3'-cyclic-nucleotide 3'-phosphodiesterase activity
mitochondrial respiratory chain complex I assembly
ubiquinol-cytochrome-c reductase activity
phosphatidyl-N-dimethylethanolamine N-methyltransferase activity
phosphatidyl-N-methylethanolamine N-methyltransferase activity
phosphatidylcholine biosynthetic process
phosphatidylethanolamine N-methyltransferase activity
N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity
purine ribonucleoside monophosphate biosynthetic process
purine ribonucleotide biosynthetic process
glycine decarboxylation via glycine cleavage system
delayed rectifier potassium channel activity
DNA replication preinitiation complex assembly
regulation of DNA-templated DNA replication initiation
3',5'-cyclic-nucleotide phosphodiesterase activity
tRNA threonylcarbamoyladenosine metabolic process
mitochondrial electron transport, ubiquinol to cytochrome c
mitochondrial respiratory chain complex III
transforming growth factor beta receptor signaling pathway
voltage-gated monoatomic ion channel activity
fructose 1,6-bisphosphate 1-phosphatase activity
L-serine-phosphatidylethanolamine phosphatidyltransferase activity
L-alpha-amino acid transmembrane transport
phosphonoacetaldehyde hydrolase activity
4-hydroxyphenylpyruvate dioxygenase activity
guanine phosphoribosyltransferase activity
hypoxanthine phosphoribosyltransferase activity
oxidoreductase activity, acting on NAD(P)H
early endosome to late endosome transport
calmodulin-dependent protein phosphatase activity
establishment of mitotic spindle orientation
monoatomic ion transmembrane transporter activity
endoplasmic reticulum membrane organization
glutathione specific gamma-glutamylcyclotransferase activity
ATP-dependent H2AZ histone chaperone activity
positive regulation of apoptotic process
O-phosphoseryl-tRNA(Sec) selenium transferase activity
conversion of seryl-tRNAsec to selenocys-tRNAsec
intramolecular phosphotransferase activity
MAP kinase tyrosine/serine/threonine phosphatase activity
TIM22 mitochondrial import inner membrane insertion complex
protein insertion into mitochondrial inner membrane
tRNA (cytidine-5-)-methyltransferase activity
3',5'-cyclic-GMP phosphodiesterase activity
organonitrogen compound metabolic process
diphosphomevalonate decarboxylase activity
isopentenyl diphosphate biosynthetic process, mevalonate pathway
modulation of chemical synaptic transmission
peptidyl-aspartic acid 3-dioxygenase activity
generation of precursor metabolites and energy
oxidoreductase activity, acting on the CH-CH group of donors
CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity
phosphatidylinositol phospholipase C activity
endoplasmic reticulum unfolded protein response
histone H4K20 methyltransferase activity
3-hydroxy-4-(trimethylammonio)butanoate anabolism
3-hydroxy-4-(trimethylammonio)butanoate biosynthesis
3-hydroxy-4-(trimethylammonio)butanoate biosynthetic process
3-hydroxy-4-(trimethylammonio)butanoate formation
3-hydroxy-4-(trimethylammonio)butanoate synthesis
Gamma-trimethyl-hydroxybutyrobetaine anabolism
Gamma-trimethyl-hydroxybutyrobetaine biosynthesis
Gamma-trimethyl-hydroxybutyrobetaine biosynthetic process
Gamma-trimethyl-hydroxybutyrobetaine formation
Gamma-trimethyl-hydroxybutyrobetaine synthesis
gamma-butyrobetaine dioxygenase activity
retinol transmembrane transporter activity
phosphatidylinositol bisphosphate binding
ubiquitin-dependent protein catabolic process via the N-end rule pathway
monocarboxylic acid transmembrane transporter activity
proton-transporting V-type ATPase, V1 domain
G protein-coupled acetylcholine receptor activity
adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway
regulation of store-operated calcium entry
positive regulation of cell population proliferation
regulation of cellular component organization
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
meiotic DNA double-strand break formation
G protein-coupled peptide receptor activity
hydroxymethylglutaryl-CoA synthase activity
endoplasmic reticulum signal peptide binding
glycoprotein 6-alpha-L-fucosyltransferase activity
vitamin transmembrane transporter activity
endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
17-alpha-hydroxyprogesterone aldolase activity
regulation of actin filament polymerization
prostaglandin-endoperoxide synthase activity
isocitrate dehydrogenase (NADP+) activity
methionyl-tRNA formyltransferase activity
aspartate family amino acid metabolic process
proteasome regulatory particle, base subcomplex
mitochondrial electron transport, succinate to ubiquinone
mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)
gamma-aminobutyric acid metabolic process
obsolete neurotransmitter catabolic process
positive regulation of nitric oxide biosynthetic process
regulation of canonical Wnt signaling pathway
L-proline transmembrane transporter activity
mRNA 3'-end processing by stem-loop binding and cleavage
mRNA cleavage and polyadenylation specificity factor complex
Glc3Man9GlcNAc2 oligosaccharide glucosidase activity
hydroxymethylglutaryl-CoA reductase (NADPH) activity
proton-transporting V-type ATPase, V0 domain
2-oxoglutarate-dependent dioxygenase activity
molybdate ion transmembrane transporter activity
peptide alpha-N-acetyltransferase activity
regulation of cytosolic calcium ion concentration
protein O-acetylglucosaminyltransferase activity
NMDA selective glutamate receptor complex
2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity
3-demethylubiquinone-9 3-O-methyltransferase activity
hexaprenyldihydroxybenzoate methyltransferase activity
obsolete tRNA (cytosine-2'-O-)-methyltransferase activity
glucosamine-6-phosphate deaminase activity
histone H3K27 methyltransferase activity
pteridine-containing compound metabolic process
Proton-transporting ATP synthase complex catalytic core F(1)
proton-transporting ATP synthase activity, rotational mechanism
proton-transporting ATP synthase complex, catalytic core F(1)
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
alpha-(1->3)-fucosyltransferase activity
phosphatidate cytidylyltransferase activity
mitochondrial inner membrane peptidase complex
protein localization to phagophore assembly site
O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity
tRNA threonylcarbamoyladenosine modification
tRNA transcription by RNA polymerase III
regulation of plasma membrane sterol distribution
melanin-concentrating hormone receptor activity
acetylcholine receptor regulator activity
adenylate cyclase-modulating G protein-coupled receptor signaling pathway
sphingolipid delta-4 desaturase activity
5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity
deadenylation-dependent decapping of nuclear-transcribed mRNA
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
4-alpha-hydroxytetrahydrobiopterin dehydratase activity
mitochondrial respiratory chain complex II assembly
retinoic acid receptor signaling pathway
cellular response to amino acid starvation
protein-N-terminal asparagine amidohydrolase activity
obsolete tRNA (adenine-N1)-methyltransferase activity
negative regulation of cell population proliferation
'de novo' NAD biosynthetic process from tryptophan
positive regulation of protein dephosphorylation
procollagen-lysine 5-dioxygenase activity
oxidized purine nucleobase lesion DNA N-glycosylase activity
L-amino acid transmembrane transporter activity
COPII-coated ER to Golgi transport vesicle
endoplasmic reticulum-Golgi intermediate compartment
aspartic endopeptidase activity, intramembrane cleaving
tetrahydrofolylpolyglutamate synthase activity
estradiol 17-beta-dehydrogenase [NAD(P)] activity
monoatomic cation transmembrane transporter activity
ethanolamine-phosphate cytidylyltransferase activity
phosphatidylethanolamine biosynthetic process
purine-nucleoside phosphorylase activity
alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity
telomerase RNA reverse transcriptase activity
3'-tRNA processing endoribonuclease activity
TRIF-dependent toll-like receptor signaling pathway
Adenosine 3',5'-phosphate biosynthetic process
Adenosine-3',5'-cyclic-monophosphate anabolism
Adenosine-3',5'-cyclic-monophosphate biosynthesis
Adenosine-3',5'-cyclic-monophosphate biosynthetic process
Adenosine-3',5'-cyclic-monophosphate formation
Adenosine-3',5'-cyclic-monophosphate synthesis
Cyclic adenylic acid biosynthetic process
endoplasmic reticulum-Golgi intermediate compartment membrane
negative regulation of cell differentiation
DNA strand elongation involved in mitotic DNA replication
oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
negative regulation of protein dephosphorylation
regulation of protein localization to plasma membrane
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
G-protein beta/gamma-subunit complex binding
mannose-ethanolamine phosphotransferase activity
tRNA-guanosine(34) queuine transglycosylase activity
iron ion transmembrane transporter activity
DNA replication, synthesis of RNA primer
organic cyclic compound metabolic process
Guanosine 3',5'-cyclic monophosphate-binding
deoxyribonucleoside 5'-monophosphate N-glycosidase activity
deoxyribonucleoside monophosphate catabolic process
THO complex part of transcription export complex
positive regulation of nuclear cell cycle DNA replication
protein serine/threonine kinase activator activity
regulation of cell cycle phase transition
chaperone cofactor-dependent protein refolding
negative regulation of gene expression, epigenetic
MyD88-dependent toll-like receptor signaling pathway
electron transport coupled proton transport
mitochondrial electron transport, cytochrome c to oxygen
histidine catabolic process to glutamate and formamide
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G protein-coupled photoreceptor activity
'de novo' cotranslational protein folding
acetyl-CoA C-myristoyltransferase activity
propanoyl-CoA C-acyltransferase activity
propionyl-CoA C2-trimethyltridecanoyltransferase activity
transcription initiation at RNA polymerase III promoter
vacuolar proton-transporting V-type ATPase complex assembly
clustering of voltage-gated sodium channels
endosome transport via multivesicular body sorting pathway
ribosomal small subunit export from nucleus
glucose transmembrane transporter activity
mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
positive regulation of DNA-templated transcription, elongation
regulation of transcription elongation by RNA polymerase II
nucleoside transmembrane transporter activity
positive regulation of innate immune response
positive regulation of DNA demethylation
pyruvate dehydrogenase (acetyl-transferring) kinase activity
assembly of large subunit precursor of preribosome
aminoacyl-tRNA synthetase multienzyme complex
positive regulation of DNA damage response, signal transduction by p53 class mediator
maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
racemase and epimerase activity, acting on carbohydrates and derivatives
peroxisome matrix targeting signal-2 binding
pyridoxal phosphate biosynthetic process
RNA N6-methyladenosine methyltransferase complex
protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
positive regulation of receptor internalization
regulation of Arp2/3 complex-mediated actin nucleation
K63-linked polyubiquitin modification-dependent protein binding
positive regulation of Wnt signaling pathway
mitochondrial proton-transporting ATP synthase, stator stalk
proton motive force-driven mitochondrial ATP synthesis
regulation of neuronal synaptic plasticity
eukaryotic translation initiation factor 2alpha kinase activity
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
phosphotransferase activity, for other substituted phosphate groups
1-phosphatidylinositol 4-kinase activity
cellular aromatic compound metabolic process
vacuolar proton-transporting V-type ATPase complex
plasma membrane proton-transporting V-type ATPase complex
G protein-coupled adenosine receptor activity
transcription cis-regulatory region binding
regulation of microtubule cytoskeleton organization
protein import into peroxisome matrix, docking
dolichol-phosphate-mannose synthase complex
glutamate-5-semialdehyde dehydrogenase activity
oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
eukaryotic translation initiation factor 2B complex
guanyl-nucleotide exchange factor complex
cyclin-dependent protein serine/threonine kinase regulator activity
delta(3)-delta(2)-enoyl-CoA isomerase activity
UTP:glucose-1-phosphate uridylyltransferase activity
negative regulation of activin receptor signaling pathway
transferase activity, transferring alkyl or aryl (other than methyl) groups
mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)
DNA-binding transcription repressor activity, RNA polymerase II-specific
sequence-specific double-stranded DNA binding
generation of catalytic spliceosome for first transesterification step
glucose-6-phosphate 1-epimerase activity
fibroblast growth factor receptor binding
fibroblast growth factor receptor signaling pathway
positive regulation of protein phosphorylation
response to endoplasmic reticulum stress
proteasome regulatory particle, lid subcomplex
peptide-methionine (R)-S-oxide reductase activity
positive regulation of cell cycle G2/M phase transition
nicotinamide-nucleotide adenylyltransferase activity
nicotinate-nucleotide adenylyltransferase activity
gamma-aminobutyric acid catabolic process
succinate-semialdehyde dehydrogenase (NAD+) activity
endoplasmic reticulum tubular network formation
succinate-CoA ligase (ADP-forming) activity
succinate-CoA ligase (GDP-forming) activity
GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity
transcription preinitiation complex assembly
pyrimidine nucleotide import into mitochondrion
pyrimidine nucleotide transmembrane transporter activity
adenylate cyclase-activating adrenergic receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
inorganic diphosphate phosphatase activity
phosphate-containing compound metabolic process
deadenylation-independent decapping of nuclear-transcribed mRNA
single-stranded DNA 5'-3' DNA exonuclease activity
K48-linked polyubiquitin modification-dependent protein binding
cysteine-type endopeptidase inhibitor activity
hydroxyacylglutathione hydrolase activity
spinal cord motor neuron cell fate specification
carbohydrate derivative biosynthetic process
glutamine-fructose-6-phosphate transaminase (isomerizing) activity
cysteine-type endopeptidase activator activity involved in apoptotic process
positive regulation of apoptotic signaling pathway
extrinsic apoptotic signaling pathway in absence of ligand
regulation of neuron projection development
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
chloride:monoatomic cation symporter activity
deoxyribonucleoside triphosphate catabolic process
nucleoside triphosphate diphosphatase activity
exonucleolytic catabolism of deadenylated mRNA
phosphate ion transmembrane transporter activity
phosphoribosylformylglycinamidine synthase activity
termination of RNA polymerase III transcription
protein-phosphatidylethanolamide deconjugating activity
inorganic phosphate transmembrane transporter activity
ferrous iron transmembrane transporter activity
O-phospho-L-serine:2-oxoglutarate aminotransferase activity
oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
late endosome to vacuole transport via multivesicular body sorting pathway
2,4-dienoyl-CoA reductase (NADPH) activity
S-adenosylhomocysteine metabolic process
eukaryotic translation initiation factor 3 complex, eIF3e
DNA recombinase auxiliary factor complex
meiotic strand invasion involved in reciprocal meiotic recombination
mitotic recombination-dependent replication fork processing
nucleotide-excision repair factor 3 complex
glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
G protein-coupled glutamate receptor binding
glycine betaine biosynthetic process from choline
general transcription initiation factor activity
DNA replication-dependent chromatin assembly
cholesterol biosynthetic process via lathosterol
regulation of microtubule polymerization or depolymerization
protein-N-terminal glutamine amidohydrolase activity
negative regulation of mRNA polyadenylation
obsolete regulation of neurotransmitter levels
L-lysine catabolic process to acetyl-CoA via L-pipecolate
single-stranded DNA exodeoxyribonuclease activity
cellular response to nitrogen starvation
transmembrane receptor protein serine/threonine kinase activity
regulation of synaptic vesicle exocytosis
transforming growth factor beta receptor activity, type II
tRNA-type intron splice site recognition and cleavage
glycine biosynthetic process from serine
glycine hydroxymethyltransferase activity
dihydropyrimidine dehydrogenase (NADP+) activity
spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
ryanodine-sensitive calcium-release channel activity
sodium:potassium-exchanging ATPase complex
negative regulation of meiotic nuclear division
single-strand selective uracil DNA N-glycosylase activity
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate
oxidoreductase activity, acting on CH-OH group of donors
adenylate cyclase-inhibiting serotonin receptor signaling pathway
nuclear origin of replication recognition complex
dystrophin-associated glycoprotein complex
unsaturated fatty acid biosynthetic process
S-adenosylmethionine biosynthetic process
S-methyl-5-thioribose-1-phosphate isomerase activity
regulation of early endosome to late endosome transport
N6-threonylcarbomyladenosine methylthiotransferase activity
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
phosphatidylserine decarboxylase activity
methylenetetrahydrofolate dehydrogenase (NADP+) activity
very-long-chain enoyl-CoA reductase activity
Guanosine 5'-monophosphate biosynthetic process
formimidoyltetrahydrofolate cyclodeaminase activity
glutamate formimidoyltransferase activity
histidine catabolic process to glutamate and formate
acetyl-CoA biosynthetic process from pyruvate
dihydrolipoyllysine-residue acetyltransferase activity
diacylglycerol O-acyltransferase activity
transcription elongation factor activity
NAD+ synthase (glutamine-hydrolyzing) activity
obsolete tRNA (guanine-N2-)-methyltransferase activity
mRNA 5'-cap (guanine-N7-)-methyltransferase activity
negative regulation of MyD88-independent toll-like receptor signaling pathway
rRNA (adenine-N6,N6-)-dimethyltransferase activity
cis-regulatory region sequence-specific DNA binding
mitochondrial oxoglutarate dehydrogenase complex
pyrroline-5-carboxylate reductase activity
6-pyruvoyltetrahydropterin synthase activity
small conductance calcium-activated potassium channel activity
hydrolase activity, acting on glycosyl bonds
termination of RNA polymerase II transcription
RNA endonuclease activity, producing 5'-phosphomonoesters
inositol monophosphate 3-phosphatase activity
inositol monophosphate 4-phosphatase activity
Branched-chain amino acid biosynthetic process
branched-chain-amino-acid transaminase activity
regulation of miRNA-mediated gene silencing
Branched-chain amino acid catabolic process
3-hydroxyisobutyrate dehydrogenase activity
mitochondrial pyruvate transmembrane transport
positive regulation of protein metabolic process
telomere maintenance via telomere lengthening
negative regulation of transcription elongation by RNA polymerase II
regulation of mitochondrial mRNA stability
regulation of cytokinesis, actomyosin contractile ring assembly
epidermal growth factor receptor signaling pathway
positive regulation of mitotic nuclear division
SRP-dependent cotranslational protein targeting to membrane, translocation
glutathione-disulfide reductase (NADP) activity
Rab-protein geranylgeranyltransferase complex
L-glutamate transmembrane transporter activity
neurotransmitter loading into synaptic vesicle
neurotransmitter transmembrane transporter activity
regulation of synapse structure or activity
superoxide-generating NAD(P)H oxidase activity
phosphogluconate dehydrogenase (decarboxylating) activity
nuclear protein quality control by the ubiquitin-proteasome system
flavin-dependent sulfhydryl oxidase activity
regulation of lipid biosynthetic process
apoptotic process involved in development
phosphatidylserine exposure on apoptotic cell surface
malate dehydrogenase (decarboxylating) (NAD+) activity
1-acylglycerophosphocholine O-acyltransferase activity
inner mitochondrial membrane organization
eukaryotic translation initiation factor 4F complex
adenyl-nucleotide exchange factor activity
obsolete acyl-coenzyme A diphosphatase activity
long-chain fatty acid-CoA ligase activity
positive regulation of neuromuscular synaptic transmission
positive regulation of fat cell differentiation
glycerophosphodiester phosphodiesterase activity
N-acylneuraminate-9-phosphate synthase activity
negative regulation of RIG-I signaling pathway
negative regulation of type I interferon production
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
organic cyclic compound biosynthetic process
organonitrogen compound biosynthetic process
secondary metabolite biosynthetic process
thiamine triphosphate phosphatase activity
regulation of glycogen metabolic process
positive regulation of B cell differentiation
fibroblast growth factor receptor activity
G protein-coupled GABA receptor activity
RNA polymerase II-specific DNA-binding transcription factor binding
RNA polymerase II C-terminal domain binding
mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity
poly(ADP-ribose) glycohydrolase activity
nucleoside diphosphate metabolic process
negative regulation of double-strand break repair via homologous recombination
mRNA (nucleoside-2'-O-)-methyltransferase activity
secondary active sulfate transmembrane transporter activity
protein-cysteine S-palmitoyltransferase activity
methylenetetrahydrofolate reductase (NAD(P)H) activity
protein-tyrosine sulfotransferase activity
negative regulation of protein phosphorylation
mitochondrial proton-transporting ATP synthase complex assembly
2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity
intraciliary transport particle B binding
3-hydroxyacyl-CoA dehydrogenase activity
mitochondrial fatty acid beta-oxidation multienzyme complex
nuclear-transcribed mRNA catabolic process, exonucleolytic
positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
positive regulation of translational initiation
establishment or maintenance of microtubule cytoskeleton polarity
orexigenic neuropeptide QRFP receptor binding
transcription elongation by mitochondrial RNA polymerase
positive regulation of Rho protein signal transduction
negative regulation of insulin receptor signaling pathway
regulation of mitochondrial membrane potential
Ric1-Rgp1 guanyl-nucleotide exchange factor complex
methylated-DNA-[protein]-cysteine S-methyltransferase activity
regulation of non-canonical NF-kappaB signal transduction
S-methyl-5-thioadenosine phosphorylase activity
phosphatidylinositol acyl-chain remodeling
Golgi to plasma membrane protein transport
initiator methionyl aminopeptidase activity
aromatic-L-amino-acid decarboxylase activity
RNA lariat debranching enzyme activator activity
RNA polymerase I general transcription initiation factor activity
transcription initiation at RNA polymerase I promoter
Golgi vesicle prefusion complex stabilization
mitochondrial outer membrane translocase complex
generation of catalytic spliceosome for second transesterification step
nuclear-transcribed mRNA poly(A) tail shortening
regulation of stem cell population maintenance
3-hydroxyisobutyryl-CoA hydrolase activity
glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex
ubiquitin-like protein transferase activity
phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity
MAP kinase kinase kinase kinase activity
exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
proton-transporting two-sector ATPase complex, catalytic domain
isopentenyl-diphosphate delta-isomerase activity
phosphatidylinositol-3-phosphate phosphatase activity
epidermal growth factor receptor binding
tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation
ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
selenocysteine insertion sequence binding
RNA polymerase I transcription regulator complex
calmodulin-lysine N-methyltransferase activity
positive regulation of mitochondrial fission
positive regulation of protein targeting to membrane
protein maturation by iron-sulfur cluster transfer
positive regulation of cytoplasmic mRNA processing body assembly
inositol heptakisphosphate kinase activity
inositol hexakisphosphate kinase activity
tRNA (guanine(46)-N7)-methyltransferase activity
resolution of meiotic recombination intermediates
lysophosphatidic acid acyltransferase activity
N-acetylglucosamine-6-sulfatase activity
1-pyrroline-5-carboxylate dehydrogenase activity
protein folding in endoplasmic reticulum
magnesium ion transmembrane transporter activity
protein serine/threonine/tyrosine kinase activity
RNA polymerase I core promoter sequence-specific DNA binding
vesicle tethering involved in exocytosis
rRNA (uridine-N3-)-methyltransferase activity
kainate selective glutamate receptor activity
kainate selective glutamate receptor complex
negative regulation of transforming growth factor beta receptor signaling pathway
positive regulation of canonical Wnt signaling pathway
regulation of proteasomal ubiquitin-dependent protein catabolic process
arginine biosynthetic process via ornithine
extracellularly ATP-gated monoatomic cation channel activity
nicotinate phosphoribosyltransferase activity
mRNA cleavage stimulating factor complex
positive regulation of myoblast differentiation
bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity
ribose phosphate diphosphokinase activity
phosphoribosylaminoimidazolecarboxamide formyltransferase activity
negative regulation of protein localization to cilium
establishment of protein localization to organelle
phosphatidylinositol-4,5-bisphosphate binding
DNA methylation-dependent heterochromatin formation
intermediate filament cytoskeleton organization
transforming growth factor beta receptor binding
protein localization to endoplasmic reticulum exit site
chondroitin sulfate biosynthetic process
glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity
Pteroylglutamic acid biosynthetic process
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity
polyribonucleotide nucleotidyltransferase activity
beta-galactoside alpha-2,6-sialyltransferase activity
negative regulation of stress granule assembly
positive regulation of intrinsic apoptotic signaling pathway
ceramide cholinephosphotransferase activity
neurotrophin TRK receptor signaling pathway
histone arginine N-methyltransferase activity
protein-arginine omega-N symmetric methyltransferase activity
DNA replication, Okazaki fragment processing
N-acylphosphatidylethanolamine-specific phospholipase D activity
glycine transmembrane transporter activity
xenobiotic detoxification by transmembrane export across the plasma membrane
xenobiotic transmembrane transporter activity
defense response to Gram-negative bacterium
defense response to Gram-positive bacterium
pyruvate dehydrogenase (acetyl-transferring) activity
proton-transporting ATP synthase complex assembly
3-hydroxybutyrate dehydrogenase activity
sno(s)RNA-containing ribonucleoprotein complex
detection of stimulus involved in sensory perception
phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DNA polymerase processivity factor activity
cAMP-dependent protein kinase inhibitor activity
protein kinase A catalytic subunit binding
glutaminyl-peptide cyclotransferase activity
arginyl-tRNA--protein transferase activity
positive regulation of flagellated sperm motility
1,4-alpha-oligoglucan phosphorylase activity
pyrimidine-nucleoside phosphorylase activity
calcium-dependent protein serine/threonine phosphatase regulator activity
negative regulation of substrate adhesion-dependent cell spreading
vesicle targeting, trans-Golgi to endosome
low-density lipoprotein particle receptor binding
heparan sulfate proteoglycan biosynthetic process
heparosan-N-sulfate-glucuronate 5-epimerase activity
glycosylphosphatidylinositol phospholipase D activity
ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
rRNA (pseudouridine) methyltransferase activity
phagolysosome assembly involved in apoptotic cell clearance
transcription initiation at mitochondrial promoter
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
positive regulation of microtubule depolymerization
protein N-linked glycosylation via asparagine
methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity
L-aspartate transmembrane transporter activity