DNA-binding transcription factor activity
proton-transporting ATPase activity, rotational mechanism
vacuolar proton-transporting V-type ATPase, V1 domain
Ubiquitin-like modifier conjugation pathway
Nicotinamide adenine dinucleotide phosphate
Nicotinic adenine dinucleotide phosphate
S-adenosylmethionine biosynthetic process
protein quality control for misfolded or incompletely synthesized proteins
regulation of transcription by RNA polymerase II
clathrin coat of trans-Golgi network vesicle
histidine catabolic process to glutamate and formamide
histidine catabolic process to glutamate and formate
ubiquitin-dependent protein catabolic process
extracellular ligand-gated monoatomic ion channel activity
transmembrane signaling receptor activity
oxidoreductase activity, acting on the CH-CH group of donors
mitochondrial outer membrane translocase complex
negative regulation of BMP signaling pathway
negative regulation of cell differentiation
regulation of synaptic transmission, cholinergic
phosphogluconate dehydrogenase (decarboxylating) activity
protein serine/threonine kinase activity
nucleobase-containing compound metabolic process
G protein-coupled peptide receptor activity
calcium-dependent cysteine-type endopeptidase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
acetylcholine-gated monoatomic cation-selective channel activity
S-adenosylmethionine-dependent methyltransferase activity
cellular aromatic compound metabolic process
cellular nitrogen compound metabolic process
organic cyclic compound metabolic process
MAP kinase tyrosine/serine/threonine phosphatase activity
peptidyl-prolyl cis-trans isomerase activity
phosphoenolpyruvate carboxykinase (GTP) activity
2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity
2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity
L-methionine salvage from S-adenosylmethionine
L-methionine salvage from methylthioadenosine
Glycosylphosphatidylinositol anchor anabolism
Glycosylphosphatidylinositol anchor biosynthesis
Glycosylphosphatidylinositol anchor biosynthetic process
Glycosylphosphatidylinositol anchor formation
Glycosylphosphatidylinositol anchor synthesis
phosphatidylinositol-3-phosphate phosphatase activity
2-aminoethylphosphonate-pyruvate transaminase activity
alanine-glyoxylate transaminase activity
RNA polymerase II cis-regulatory region sequence-specific DNA binding
positive regulation of DNA-templated transcription
proteasome core complex, alpha-subunit complex
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of monoatomic ion transmembrane transport
voltage-gated potassium channel activity
malonate-semialdehyde dehydrogenase (acetylating) activity
methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity
regulation of proteasomal ubiquitin-dependent protein catabolic process
monoatomic ion transmembrane transporter activity
retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
negative regulation of double-strand break repair via homologous recombination
L-tyrosine:2-oxoglutarate aminotransferase activity
purine-nucleoside phosphorylase activity
copper ion transmembrane transporter activity
minus-end-directed microtubule motor activity
regulation of DNA-templated transcription
DNA-binding transcription factor activity, RNA polymerase II-specific
small conductance calcium-activated potassium channel activity
endoplasmic reticulum to Golgi vesicle-mediated transport
endoplasmic reticulum-Golgi intermediate compartment
double-strand break repair via nonhomologous end joining
linear malto-oligosaccharide phosphorylase activity
glycine biosynthetic process from serine
glycine hydroxymethyltransferase activity
DNA-binding transcription activator activity, RNA polymerase II-specific
regulation of stem cell population maintenance
N,N-dimethylaniline monooxygenase activity
mitochondrial electron transport, cytochrome c to oxygen
mitochondrial respiratory chain complex IV
non-membrane spanning protein tyrosine kinase activity
cAMP-dependent protein kinase regulator activity
pyrroline-5-carboxylate reductase activity
adenosylmethionine decarboxylase activity
G protein-coupled receptor signaling pathway
G-protein beta/gamma-subunit complex binding
hydrolase activity, hydrolyzing O-glycosyl compounds
oxidative single-stranded DNA demethylation
nucleoside transmembrane transporter activity
endoplasmic reticulum-Golgi intermediate compartment membrane
cyclin-dependent protein serine/threonine kinase regulator activity
ATP-dependent DNA damage sensor activity
L-aspartate:2-oxoglutarate aminotransferase activity
negative regulation of signal transduction
regulation of G protein-coupled receptor signaling pathway
DNA-directed 5'-3' RNA polymerase activity
phosphatidylinositol-4-phosphate binding
metal ion transmembrane transporter activity
3',5'-cyclic-nucleotide phosphodiesterase activity
regulation of mitotic cell cycle spindle assembly checkpoint
regulation of microtubule cytoskeleton organization
serine-type endopeptidase inhibitor activity
pyrimidine nucleotide-sugar transmembrane transporter activity
RNA polymerase II CTD heptapeptide repeat phosphatase activity
protein tyrosine/serine/threonine phosphatase activity
deadenylation-dependent decapping of nuclear-transcribed mRNA
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
proteolysis involved in protein catabolic process
mitochondrial electron transport, ubiquinol to cytochrome c
mitochondrial respiratory chain complex III
transmembrane receptor protein serine/threonine kinase activity
inward rectifier potassium channel activity
eukaryotic translation initiation factor 3 complex, eIF3e
formation of cytoplasmic translation initiation complex
glutathione specific gamma-glutamylcyclotransferase activity
small GTPase mediated signal transduction
G protein-coupled GABA receptor activity
oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
peptide-methionine (R)-S-oxide reductase activity
molybdate ion transmembrane transporter activity
FAD-dependent H3K4me/H3K4me3 demethylase activity
RNA polymerase II C-terminal domain binding
mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity
2,4-dienoyl-CoA reductase (NADPH) activity
Adenosine 5'-triphosphate biosynthetic process
Adenosine triphosphate biosynthetic process
Proton-transporting ATP synthase complex coupling factor F(0)
proton-transporting ATP synthase complex, coupling factor F(o)
ubiquitin-protein transferase activator activity
monoatomic anion transmembrane transporter activity
glutamate-cysteine ligase catalytic subunit binding
protein serine/threonine/tyrosine kinase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
proteasome regulatory particle, base subcomplex
organonitrogen compound metabolic process
regulation of microtubule polymerization or depolymerization
generation of catalytic spliceosome for second transesterification step
1-alkyl-2-acetylglycerophosphocholine esterase activity
proteasome core complex, beta-subunit complex
peptide alpha-N-acetyltransferase activity
tRNA wobble adenosine to inosine editing
tRNA-specific adenosine-34 deaminase activity
establishment of mitotic spindle orientation
monoatomic cation transmembrane transporter activity
regulation of ARF protein signal transduction
proton-transporting V-type ATPase, V0 domain
positive regulation of cell cycle G2/M phase transition
long-chain fatty acid import into peroxisome
long-chain fatty acid transporter activity
MyD88-dependent toll-like receptor signaling pathway
positive regulation of canonical NF-kappaB signal transduction
carbohydrate derivative biosynthetic process
glutamine-fructose-6-phosphate transaminase (isomerizing) activity
N-acetylmuramoyl-L-alanine amidase activity
nuclear-transcribed mRNA catabolic process
hydrolase activity, hydrolyzing N-glycosyl compounds
adenyl-nucleotide exchange factor activity
regulation of canonical Wnt signaling pathway
tryptophan catabolic process to kynurenine
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
3-demethoxyubiquinol 3-hydroxylase activity
extrinsic component of mitochondrial inner membrane
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
galactosylceramide sulfotransferase activity
protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
bis(5'-nucleosyl)-tetraphosphatase activity
L-ascorbic acid transmembrane transporter activity
protein-lysine N-methyltransferase activity
regulation of cellular component organization
nuclear origin of replication recognition complex
P450-containing electron transport chain
eukaryotic translation initiation factor 3 complex
oxidoreductase activity, acting on NAD(P)H
1,4-alpha-oligoglucan phosphorylase activity
pyrimidine-nucleoside phosphorylase activity
negative regulation of apoptotic process
regulation of actin filament polymerization
xenobiotic transmembrane transporter activity
mitochondrial respiratory chain complex I
phosphotransferase activity, for other substituted phosphate groups
double-strand break repair via homologous recombination
mitotic recombination-dependent replication fork processing
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
protoporphyrinogen IX biosynthetic process
deadenylation-independent decapping of nuclear-transcribed mRNA
mitochondrial pyruvate transmembrane transport
negative regulation of DNA-templated transcription
phosphatidylethanolamine biosynthetic process
phosphatidylserine decarboxylase activity
transcription initiation at RNA polymerase II promoter
cellular response to amino acid stimulus
UTP:glucose-1-phosphate uridylyltransferase activity
N-acylsphingosine amidohydrolase activity
phosphotransferase activity, alcohol group as acceptor
protein-cysteine S-palmitoyltransferase activity
proton-transporting V-type ATPase, V1 domain
NADH dehydrogenase (ubiquinone) activity
protein-arginine N-methyltransferase activity
'de novo' NAD biosynthetic process from tryptophan
3-hydroxyanthranilate 3,4-dioxygenase activity
TIM22 mitochondrial import inner membrane insertion complex
protein insertion into mitochondrial inner membrane
protein transmembrane transporter activity
mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
Arp2/3 complex-mediated actin nucleation
vacuolar proton-transporting V-type ATPase complex assembly
TIM23 mitochondrial import inner membrane translocase complex
protein import into mitochondrial matrix
mitochondrial inner membrane peptidase complex
protein processing involved in protein targeting to mitochondrion
deoxyribonucleotide biosynthetic process
protein-disulfide reductase (NAD(P)) activity
cysteine-type endopeptidase inhibitor activity
glutathione dehydrogenase (ascorbate) activity
negative regulation of actin filament polymerization
cilium movement involved in cell motility
G protein-coupled receptor kinase activity
G protein-coupled acetylcholine receptor activity
N-acetylgalactosamine-6-sulfatase activity
positive regulation of transcription by RNA polymerase II
calmodulin-lysine N-methyltransferase activity
positive regulation of translational elongation
positive regulation of translational termination
transcription initiation at RNA polymerase III promoter
acyltransferase activity, transferring groups other than amino-acyl groups
mitochondrial ADP transmembrane transport
mitochondrial ATP transmembrane transport
N-acetylgalactosamine-6-phosphate deacetylase activity
N-acetylglucosamine-6-phosphate deacetylase activity
aminocarboxymuconate-semialdehyde decarboxylase activity
negative regulation of quinolinate biosynthetic process
glucose-6-phosphate dehydrogenase activity
maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Adenosine 3',5'-phosphate biosynthetic process
Adenosine-3',5'-cyclic-monophosphate anabolism
Adenosine-3',5'-cyclic-monophosphate biosynthesis
Adenosine-3',5'-cyclic-monophosphate biosynthetic process
Adenosine-3',5'-cyclic-monophosphate formation
Adenosine-3',5'-cyclic-monophosphate synthesis
Cyclic adenylic acid biosynthetic process
'de novo' pyrimidine nucleobase biosynthetic process
orotate phosphoribosyltransferase activity
orotidine-5'-phosphate decarboxylase activity
regulation of nitrogen compound metabolic process
alcohol-forming long-chain fatty acyl-CoA reductase activity
alcohol-forming very long-chain fatty acyl-CoA reductase activity
SRP-dependent cotranslational protein targeting to membrane
endoplasmic reticulum signal peptide binding
signal recognition particle, endoplasmic reticulum targeting
tRNA-5-taurinomethyluridine 2-sulfurtransferase
riboflavin transmembrane transporter activity
P-type transmembrane transporter activity
pyridoxal phosphate biosynthetic process
negative regulation of transcription by RNA polymerase II
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
negative regulation of biosynthetic process
3-oxo-5-alpha-steroid 4-dehydrogenase activity
3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
transferase activity, transferring alkyl or aryl (other than methyl) groups
phosphatidylinositol phosphate phosphatase activity
THO complex part of transcription export complex
transcription elongation by RNA polymerase II
RNA polymerase II general transcription initiation factor activity
GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity
GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase activity
negative regulation of Wnt signaling pathway
chloride:monoatomic cation symporter activity
RNA polymerase II transcription regulatory region sequence-specific DNA binding
cytochrome-b5 reductase activity, acting on NAD(P)H
transcription preinitiation complex assembly
transcription cis-regulatory region binding
acetylgalactosaminyltransferase activity
UDP-N-acetylglucosamine biosynthetic process
phosphoacetylglucosamine mutase activity
sodium:potassium-exchanging ATPase complex
nuclear DNA-directed RNA polymerase complex
isocitrate dehydrogenase (NADP+) activity
protein-arginine omega-N asymmetric methyltransferase activity
hydrolase activity, acting on ester bonds
sugar transmembrane transporter activity
late endosome to vacuole transport via multivesicular body sorting pathway
3-hydroxyacyl-CoA dehydrogenase activity
mitochondrial fatty acid beta-oxidation multienzyme complex
ubiquitin-like modifier activating enzyme activity
dolichyl-diphosphooligosaccharide-protein glycotransferase activity
calcium,diacylglycerol-dependent serine/threonine kinase activity
ATP-dependent chromatin remodeler activity
glycine decarboxylation via glycine cleavage system
negative regulation of translational initiation
protein-phosphatidylethanolamide deconjugating activity
intracellular membrane-bounded organelle
positive regulation of transcription elongation by RNA polymerase II
guanyl-nucleotide exchange factor activity
malate dehydrogenase (decarboxylating) (NAD+) activity
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
Guanosine 3',5'-cyclic monophosphate-binding
poly(U)-specific exoribonuclease activity, producing 3' uridine cyclic phosphate ends
1,4-alpha-glucan branching enzyme activity
1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis)
protein serine/threonine phosphatase activity
protein folding in endoplasmic reticulum
negative regulation of transforming growth factor beta receptor signaling pathway
glucose-6-phosphate 1-epimerase activity
farnesyl diphosphate biosynthetic process, mevalonate pathway
hydroxymethylglutaryl-CoA synthase activity
cyclin-dependent protein serine/threonine kinase activator activity
galactoside 2-alpha-L-fucosyltransferase activity
establishment of mitotic spindle localization
mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
proton motive force-driven ATP synthesis
proton transmembrane transporter activity
negative regulation of transcription by RNA polymerase III
regulation of alternative mRNA splicing, via spliceosome
alkylglycerone-phosphate synthase activity
vacuolar proton-transporting V-type ATPase complex
purine-rich negative regulatory element binding
deoxyribonucleoside triphosphate catabolic process
nucleoside triphosphate diphosphatase activity
protein maturation by [4Fe-4S] cluster transfer
CAAX-protein geranylgeranyltransferase activity
CAAX-protein geranylgeranyltransferase complex
negative regulation of translational elongation
procollagen-lysine 5-dioxygenase activity
dehydrodolichyl diphosphate synthase activity
homophilic cell adhesion via plasma membrane adhesion molecules
secondary active sulfate transmembrane transporter activity
regulation of complement activation, lectin pathway
fructose 1,6-bisphosphate 1-phosphatase activity
DNA-3-methyladenine glycosylase activity
DNA-3-methylguanine glycosylase activity
DNA-7-methyladenine glycosylase activity
DNA-7-methylguanine glycosylase activity
proton-transporting two-sector ATPase complex, catalytic domain
2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity
eukaryotic translation elongation factor 1 complex
transmembrane receptor protein tyrosine kinase activity
protein maturation by iron-sulfur cluster transfer
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
O-phospho-L-serine:2-oxoglutarate aminotransferase activity
voltage-gated monoatomic ion channel activity
adenylate cyclase-modulating G protein-coupled receptor signaling pathway
histone H3K4me/H3K4me2/H3K4me3 demethylase activity
nicotinate phosphoribosyltransferase activity
positive regulation of protein dephosphorylation
succinate-CoA ligase (ADP-forming) activity
mitochondrial respiratory chain complex I assembly
3-oxoacyl-[acyl-carrier-protein] synthase activity
proteasome regulatory particle, lid subcomplex
retinol transmembrane transporter activity
RNA polymerase I core promoter sequence-specific DNA binding
ligand-gated monoatomic ion channel activity
histone H4K20 methyltransferase activity
carbohydrate derivative metabolic process
anaphase-promoting complex-dependent catabolic process
DNA polymerase processivity factor activity
ATP synthesis coupled electron transport
positive regulation of SREBP signaling pathway
mitochondrial respiratory chain complex II assembly
positive regulation of DNA-templated transcription, elongation
intracellular non-membrane-bounded organelle
ATPase-coupled intramembrane lipid transporter activity
extracellularly ATP-gated monoatomic cation channel activity
ribose phosphate diphosphokinase activity
endoplasmic reticulum tubular network formation
O-phosphoseryl-tRNA(Sec) selenium transferase activity
conversion of seryl-tRNAsec to selenocys-tRNAsec
L-alpha-amino acid transmembrane transport
isopentenyl diphosphate biosynthetic process, mevalonate pathway
positive regulation of transcription initiation by RNA polymerase II
methylthioribulose 1-phosphate dehydratase activity
peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity
single-strand selective uracil DNA N-glycosylase activity
general transcription initiation factor activity
2-(3-amino-3-carboxypropyl)histidine synthase activity
Rab-protein geranylgeranyltransferase complex
proton-transporting ATP synthase activity, rotational mechanism
proton-transporting ATP synthase complex, catalytic core F(1)
positive regulation of apoptotic process
tRNA (cytidine(32)-2'-O)-methyltransferase activity
nucleobase-containing compound kinase activity
NAD+ synthase (glutamine-hydrolyzing) activity
1-phosphatidylinositol 4-kinase activity
phosphatidylinositol phosphate biosynthetic process
Molybdenum cofactor biosynthetic process
Mo-molybdopterin cofactor biosynthetic process
molybdopterin molybdotransferase activity
obsolete tRNA (adenine-N1)-methyltransferase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
adenylate cyclase-activating G protein-coupled receptor signaling pathway
miRNA-mediated gene silencing by inhibition of translation
voltage-gated monoatomic anion channel activity
protein carboxyl O-methyltransferase activity
proton-transporting ATP synthase complex assembly
G protein-coupled serotonin receptor activity
Guanosine 5'-monophosphate biosynthetic process
glutamate dehydrogenase [NAD(P)+] activity
cyclin-dependent protein serine/threonine kinase activity
aspartic endopeptidase activity, intramembrane cleaving
RNA polymerase II preinitiation complex assembly
Glc3Man9GlcNAc2 oligosaccharide glucosidase activity
protein import into mitochondrial intermembrane space
formation of translation preinitiation complex
termination of RNA polymerase II transcription
calcium-dependent protein serine/threonine phosphatase regulator activity
transcription-coupled nucleotide-excision repair
rRNA (uridine-N3-)-methyltransferase activity
thiomorpholine-carboxylate dehydrogenase activity
purine ribonucleoside monophosphate biosynthetic process
regulation of small GTPase mediated signal transduction
RNA endonuclease activity, producing 5'-phosphomonoesters
Ric1-Rgp1 guanyl-nucleotide exchange factor complex
negative regulation of RIG-I signaling pathway
negative regulation of type I interferon production
regulation of transcription elongation by RNA polymerase II
intramolecular phosphotransferase activity
ubiquitin-like protein transferase activity
8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity
neurotrophin TRK receptor signaling pathway