999552:METH RS07690
gene id: 999552:METH_RS07690
uniprot id: V9VPL3
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

999552:METH RS11060
gene id: 999552:METH_RS11060
uniprot id: V9VU37
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

999552:METH RS02910
gene id: 999552:METH_RS02910
uniprot id: V9VPB2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

999552:METH RS04215
gene id: 999552:METH_RS04215
uniprot id: V9VT51
names: Similarity
messages: Belongs to the AHA1 family.

999552:METH RS20715
gene id: 999552:METH_RS20715
uniprot id: V9VZS6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

999552:METH RS09870
gene id: 999552:METH_RS09870
uniprot id: V9VQL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

999552:METH RS02570
gene id: 999552:METH_RS02570
uniprot id: V9VMI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

999552:METH RS01335
gene id: 999552:METH_RS01335
uniprot id: V9VLU6
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

999552:METH RS14310
gene id: 999552:METH_RS14310
uniprot id: V9VY42
names: Similarity
messages: Belongs to the transglycosylase Slt family.
messages: Belongs to the virb1 family.

999552:METH RS02505
gene id: 999552:METH_RS02505
uniprot id: V9VP29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

999552:METH RS18990
gene id: 999552:METH_RS18990
uniprot id: V9VYY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

999552:METH RS13915
gene id: 999552:METH_RS13915
uniprot id: V9VUS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

999552:METH RS08620
gene id: 999552:METH_RS08620
uniprot id: V9VSZ3
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

999552:METH RS18805
gene id: 999552:METH_RS18805
uniprot id: V9VYV3
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

999552:METH RS10640
gene id: 999552:METH_RS10640
uniprot id: V9VWB0
names: Similarity
messages: Belongs to the autoinducer synthase family.

999552:METH RS15845
gene id: 999552:METH_RS15845
uniprot id: V9VVS2
names: Similarity
messages: Belongs to the glutamine synthetase family.

999552:METH RS11495
gene id: 999552:METH_RS11495
uniprot id: V9VRE4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS18245
gene id: 999552:METH_RS18245
uniprot id: V9VUN3
names: Cofactor
messages: Binds 1 zinc ion per subunit.

999552:METH RS14140
gene id: 999552:METH_RS14140
uniprot id: V9VV43
names: Similarity
messages: Belongs to the TPP enzyme family.

999552:METH RS14790
gene id: 999552:METH_RS14790
uniprot id: V9VVC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

999552:METH RS21570
gene id: 999552:METH_RS21570
uniprot id: V9W384
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

999552:METH RS06930
gene id: 999552:METH_RS06930
uniprot id: V9VUF9
names: Similarity
messages: Belongs to the ArsC family.

999552:METH RS14415
gene id: 999552:METH_RS14415
uniprot id: V9VY59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

999552:METH RS06340
gene id: 999552:METH_RS06340
uniprot id: V9VQZ5
names: Similarity
messages: Belongs to the thioesterase PaaI family.

999552:METH RS07340
gene id: 999552:METH_RS07340
uniprot id: V9VRC8
names: Subcellular Location Annotation
messages: Cell inner membrane

999552:METH RS13990
gene id: 999552:METH_RS13990
uniprot id: V9VWP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

999552:METH RS01650
gene id: 999552:METH_RS01650
uniprot id: V9VLZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

999552:METH RS04430
gene id: 999552:METH_RS04430
uniprot id: V9VPY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

999552:METH RS00885
gene id: 999552:METH_RS00885
uniprot id: V9VQ42
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

999552:METH RS19800
gene id: 999552:METH_RS19800
uniprot id: V9VZD2
names: Similarity
messages: Belongs to the type III secretion exporter family.

999552:METH RS01045
gene id: 999552:METH_RS01045
uniprot id: V9VLP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

999552:METH RS22130
gene id: 999552:METH_RS22130
uniprot id: V9W1C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

999552:METH RS13040
gene id: 999552:METH_RS13040
uniprot id: V9VXJ0
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS14760
gene id: 999552:METH_RS14760
uniprot id: V9VVB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

999552:METH RS02575
gene id: 999552:METH_RS02575
uniprot id: V9VSF1
names: Subcellular Location Annotation
messages: Cell inner membrane

999552:METH RS21225
gene id: 999552:METH_RS21225
uniprot id: V9W0L7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS05990
gene id: 999552:METH_RS05990
uniprot id: V9VNY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Cytoplasm
messages: Homodimer.

999552:METH RS12895
gene id: 999552:METH_RS12895
uniprot id: V9VV17
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

999552:METH RS05030
gene id: 999552:METH_RS05030
uniprot id: V9VQB5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

999552:METH RS13325
gene id: 999552:METH_RS13325
uniprot id: V9VXP2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

999552:METH RS19760
gene id: 999552:METH_RS19760
uniprot id: V9W0Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

999552:METH RS21160
gene id: 999552:METH_RS21160
uniprot id: V9VXS1
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

999552:METH RS10070
gene id: 999552:METH_RS10070
uniprot id: V9VTN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

999552:METH RS00005
gene id: 999552:METH_RS00005
uniprot id: V9VR32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

999552:METH RS10250
gene id: 999552:METH_RS10250
uniprot id: V9VST5
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

999552:METH RS00235
gene id: 999552:METH_RS00235
uniprot id: V9VPU6
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS20590
gene id: 999552:METH_RS20590
uniprot id: V9W2L3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

999552:METH RS20930
gene id: 999552:METH_RS20930
uniprot id: V9W2S9
names: Similarity
messages: Belongs to the PrpD family.

999552:METH RS16205
gene id: 999552:METH_RS16205
uniprot id: V9VXM7
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS12985
gene id: 999552:METH_RS12985
uniprot id: V9VS51
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

999552:METH RS14265
gene id: 999552:METH_RS14265
uniprot id: V9VV55
names: Similarity
messages: Belongs to the TPP enzyme family.

999552:METH RS17920
gene id: 999552:METH_RS17920
uniprot id: V9VWR8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

999552:METH RS17320
gene id: 999552:METH_RS17320
uniprot id: V9VY56
names: Similarity
messages: Belongs to the ABC transporter superfamily.

999552:METH RS01110
gene id: 999552:METH_RS01110
uniprot id: V9VRK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

999552:METH RS24975
gene id: 999552:METH_RS24975
uniprot id: V9VX29
names: Similarity
messages: Belongs to the multicopper oxidase family.

999552:METH RS21265
gene id: 999552:METH_RS21265
uniprot id: V9W306
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

999552:METH RS09390
gene id: 999552:METH_RS09390
uniprot id: V9VQC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

999552:METH RS14890
gene id: 999552:METH_RS14890
uniprot id: V9VT50
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS19765
gene id: 999552:METH_RS19765
uniprot id: V9VXR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

999552:METH RS00065
gene id: 999552:METH_RS00065
uniprot id: V9VNP0
names: Similarity
messages: Belongs to the peptidase M16 family.

999552:METH RS11125
gene id: 999552:METH_RS11125
uniprot id: V9VR54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

999552:METH RS22205
gene id: 999552:METH_RS22205
uniprot id: V9W1E4
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

999552:METH RS12865
gene id: 999552:METH_RS12865
uniprot id: V9VV13
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

999552:METH RS02895
gene id: 999552:METH_RS02895
uniprot id: V9VR83
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

999552:METH RS12920
gene id: 999552:METH_RS12920
uniprot id: V9VV20
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

999552:METH RS20875
gene id: 999552:METH_RS20875
uniprot id: V9W1B7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. L-carnitine dehydrogenase subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3-dehydrocarnitine.
messages: Cytoplasm
messages: Homodimer.

999552:METH RS11950
gene id: 999552:METH_RS11950
uniprot id: V9VVK5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS09770
gene id: 999552:METH_RS09770
uniprot id: V9VQJ1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

999552:METH RS13790
gene id: 999552:METH_RS13790
uniprot id: V9VWI7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

999552:METH RS20310
gene id: 999552:METH_RS20310
uniprot id: V9VZI9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

999552:METH RS07550
gene id: 999552:METH_RS07550
uniprot id: V9VTG7
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS03325
gene id: 999552:METH_RS03325
uniprot id: V9VQD9
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS15550
gene id: 999552:METH_RS15550
uniprot id: V9VTF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

999552:METH RS18475
gene id: 999552:METH_RS18475
uniprot id: V9W017
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

999552:METH RS20255
gene id: 999552:METH_RS20255
uniprot id: V9VX63
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

999552:METH RS20920
gene id: 999552:METH_RS20920
uniprot id: V9W1C7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS04650
gene id: 999552:METH_RS04650
uniprot id: V9VR00
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

999552:METH RS17000
gene id: 999552:METH_RS17000
uniprot id: V9VXZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

999552:METH RS14815
gene id: 999552:METH_RS14815
uniprot id: V9VVC4
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

999552:METH RS17550
gene id: 999552:METH_RS17550
uniprot id: V9VUB1
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

999552:METH RS17790
gene id: 999552:METH_RS17790
uniprot id: V9VWP8
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

999552:METH RS02130
gene id: 999552:METH_RS02130
uniprot id: V9VS44
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

999552:METH RS21035
gene id: 999552:METH_RS21035
uniprot id: V9W0H5
names: Similarity
messages: Belongs to the universal stress protein A family.

999552:METH RS10930
gene id: 999552:METH_RS10930
uniprot id: V9VV36
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

999552:METH RS09670
gene id: 999552:METH_RS09670
uniprot id: V9VTF8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

999552:METH RS02370
gene id: 999552:METH_RS02370
uniprot id: V9VNY7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

999552:METH RS09420
gene id: 999552:METH_RS09420
uniprot id: V9VVM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

999552:METH RS18040
gene id: 999552:METH_RS18040
uniprot id: V9VYG7
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

999552:METH RS00620
gene id: 999552:METH_RS00620
uniprot id: V9VNY1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

999552:METH RS05680
gene id: 999552:METH_RS05680
uniprot id: V9VNT5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

999552:METH RS04860
gene id: 999552:METH_RS04860
uniprot id: V9VR36
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

999552:METH RS07195
gene id: 999552:METH_RS07195
uniprot id: V9VS92
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS20595
gene id: 999552:METH_RS20595
uniprot id: V9VZQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

999552:METH RS14495
gene id: 999552:METH_RS14495
uniprot id: V9VV87
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS12555
gene id: 999552:METH_RS12555
uniprot id: V9VRX2
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

999552:METH RS05405
gene id: 999552:METH_RS05405
uniprot id: V9VSJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

999552:METH RS19275
gene id: 999552:METH_RS19275
uniprot id: V9VXG9
names: Similarity
messages: Belongs to the Tim44 family.

999552:METH RS20610
gene id: 999552:METH_RS20610
uniprot id: V9VXF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

999552:METH RS17010
gene id: 999552:METH_RS17010
uniprot id: V9VZB8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

999552:METH RS19525
gene id: 999552:METH_RS19525
uniprot id: V9VZ85
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

999552:METH RS01380
gene id: 999552:METH_RS01380
uniprot id: V9VQD6
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

999552:METH RS15625
gene id: 999552:METH_RS15625
uniprot id: V9VYP8
names: Similarity
messages: Belongs to the GST superfamily.

999552:METH RS13490
gene id: 999552:METH_RS13490
uniprot id: V9VUH7
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS08205
gene id: 999552:METH_RS08205
uniprot id: V9VPV4
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS12430
gene id: 999552:METH_RS12430
uniprot id: V9VX66
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

999552:METH RS13750
gene id: 999552:METH_RS13750
uniprot id: V9VWI2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

999552:METH RS06140
gene id: 999552:METH_RS06140
uniprot id: V9VNZ9
names: Similarity
messages: Belongs to the ArsC family.

999552:METH RS07065
gene id: 999552:METH_RS07065
uniprot id: V9VR82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

999552:METH RS21505
gene id: 999552:METH_RS21505
uniprot id: V9W365
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

999552:METH RS15995
gene id: 999552:METH_RS15995
uniprot id: V9VXJ1
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS02190
gene id: 999552:METH_RS02190
uniprot id: V9VS56
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

999552:METH RS20845
gene id: 999552:METH_RS20845
uniprot id: V9W0C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

999552:METH RS22230
gene id: 999552:METH_RS22230
uniprot id: V9W1E9
names: Similarity
messages: Belongs to the peptidase C14A family.

999552:METH RS09495
gene id: 999552:METH_RS09495
uniprot id: V9VQE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

999552:METH RS16910
gene id: 999552:METH_RS16910
uniprot id: V9VW98
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

999552:METH RS02770
gene id: 999552:METH_RS02770
uniprot id: V9VP93
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS22190
gene id: 999552:METH_RS22190
uniprot id: V9VYK9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

999552:METH RS19795
gene id: 999552:METH_RS19795
uniprot id: V9VYD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Membrane

999552:METH RS14080
gene id: 999552:METH_RS14080
uniprot id: V9VV37
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS04990
gene id: 999552:METH_RS04990
uniprot id: V9VS95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

999552:METH RS10940
gene id: 999552:METH_RS10940
uniprot id: V9VWF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

999552:METH RS21425
gene id: 999552:METH_RS21425
uniprot id: V9W1P9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

999552:METH RS07110
gene id: 999552:METH_RS07110
uniprot id: V9VUJ4
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

999552:METH RS03410
gene id: 999552:METH_RS03410
uniprot id: V9VMV1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

999552:METH RS09070
gene id: 999552:METH_RS09070
uniprot id: V9VU87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

999552:METH RS19490
gene id: 999552:METH_RS19490
uniprot id: V9VXL2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

999552:METH RS14250
gene id: 999552:METH_RS14250
uniprot id: V9VSU3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

999552:METH RS18310
gene id: 999552:METH_RS18310
uniprot id: V9VXM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

999552:METH RS11515
gene id: 999552:METH_RS11515
uniprot id: V9VVE8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

999552:METH RS02645
gene id: 999552:METH_RS02645
uniprot id: V9VP71
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS09815
gene id: 999552:METH_RS09815
uniprot id: V9VUM4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS18965
gene id: 999552:METH_RS18965
uniprot id: V9VUY8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

999552:METH RS18995
gene id: 999552:METH_RS18995
uniprot id: V9VUZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

999552:METH RS02495
gene id: 999552:METH_RS02495
uniprot id: V9VMD9
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

999552:METH RS08190
gene id: 999552:METH_RS08190
uniprot id: V9VRU5
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

999552:METH RS13615
gene id: 999552:METH_RS13615
uniprot id: V9VSG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

999552:METH RS22315
gene id: 999552:METH_RS22315
uniprot id: V9W2C5
names: Similarity
messages: Belongs to the ClpA/ClpB family.

999552:METH RS04940
gene id: 999552:METH_RS04940
uniprot id: V9VS85
names: Similarity
messages: Belongs to the UPF0235 family.

999552:METH RS00935
gene id: 999552:METH_RS00935
uniprot id: V9VP39
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

999552:METH RS16535
gene id: 999552:METH_RS16535
uniprot id: V9VZ70
names: Similarity
messages: Belongs to the peptidase S1B family.

999552:METH RS07900
gene id: 999552:METH_RS07900
uniprot id: V9VTN2
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

999552:METH RS12285
gene id: 999552:METH_RS12285
uniprot id: V9VVQ0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

999552:METH RS02625
gene id: 999552:METH_RS02625
uniprot id: V9VR42
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.
messages: Membrane

999552:METH RS11520
gene id: 999552:METH_RS11520
uniprot id: V9VRE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

999552:METH RS17760
gene id: 999552:METH_RS17760
uniprot id: V9VZP0
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

999552:METH RS19530
gene id: 999552:METH_RS19530
uniprot id: V9VV80
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

999552:METH RS01355
gene id: 999552:METH_RS01355
uniprot id: V9VQD1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

999552:METH RS08625
gene id: 999552:METH_RS08625
uniprot id: V9VU25
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS09120
gene id: 999552:METH_RS09120
uniprot id: V9VSA0
names: Similarity
messages: Belongs to the universal stress protein A family.

999552:METH RS17770
gene id: 999552:METH_RS17770
uniprot id: V9VXC3
names: Similarity
messages: Belongs to the peptidase M17 family.

999552:METH RS09710
gene id: 999552:METH_RS09710
uniprot id: V9VSJ3
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

999552:METH RS04815
gene id: 999552:METH_RS04815
uniprot id: V9VS54
names: Subcellular Location Annotation
messages: Mitochondrion

999552:METH RS19790
gene id: 999552:METH_RS19790
uniprot id: V9VXR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

999552:METH RS20265
gene id: 999552:METH_RS20265
uniprot id: V9VZH3
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

999552:METH RS22045
gene id: 999552:METH_RS22045
uniprot id: V9W174
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

999552:METH RS03225
gene id: 999552:METH_RS03225
uniprot id: V9VMS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

999552:METH RS06820
gene id: 999552:METH_RS06820
uniprot id: V9VT37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.
messages: The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.

999552:METH RS21990
gene id: 999552:METH_RS21990
uniprot id: V9W239
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

999552:METH RS11310
gene id: 999552:METH_RS11310
uniprot id: V9VWN1
names: Similarity
messages: Belongs to the selenium-binding protein family.

999552:METH RS17245
gene id: 999552:METH_RS17245
uniprot id: V9VU62
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

999552:METH RS05660
gene id: 999552:METH_RS05660
uniprot id: V9VTZ1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

999552:METH RS11120
gene id: 999552:METH_RS11120
uniprot id: V9VV69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

999552:METH RS02755
gene id: 999552:METH_RS02755
uniprot id: V9VR65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

999552:METH RS18075
gene id: 999552:METH_RS18075
uniprot id: V9VZU3
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

999552:METH RS18365
gene id: 999552:METH_RS18365
uniprot id: V9VYM4
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

999552:METH RS11865
gene id: 999552:METH_RS11865
uniprot id: V9VTP8
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

999552:METH RS09845
gene id: 999552:METH_RS09845
uniprot id: V9VVV9
names: Similarity
messages: Belongs to the GcvT family.

999552:METH RS11920
gene id: 999552:METH_RS11920
uniprot id: V9VUM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

999552:METH RS17990
gene id: 999552:METH_RS17990
uniprot id: V9VYF9
names: Similarity
messages: Belongs to the hyi family.

999552:METH RS21235
gene id: 999552:METH_RS21235
uniprot id: V9VXT6
names: Similarity
messages: Belongs to the GcvT family.

999552:METH RS08375
gene id: 999552:METH_RS08375
uniprot id: V9VPX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

999552:METH RS01040
gene id: 999552:METH_RS01040
uniprot id: V9VQ72
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

999552:METH RS20745
gene id: 999552:METH_RS20745
uniprot id: V9W096
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

999552:METH RS00130
gene id: 999552:METH_RS00130
uniprot id: V9VLA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

999552:METH RS13980
gene id: 999552:METH_RS13980
uniprot id: V9VV27
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

999552:METH RS17870
gene id: 999552:METH_RS17870
uniprot id: V9VXE2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

999552:METH RS08025
gene id: 999552:METH_RS08025
uniprot id: V9VSM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

999552:METH RS03140
gene id: 999552:METH_RS03140
uniprot id: V9VRC1
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

999552:METH RS16715
gene id: 999552:METH_RS16715
uniprot id: V9VWU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

999552:METH RS00930
gene id: 999552:METH_RS00930
uniprot id: V9VN69
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

999552:METH RS18980
gene id: 999552:METH_RS18980
uniprot id: V9VXB2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

999552:METH RS21260
gene id: 999552:METH_RS21260
uniprot id: V9VXU0
names: Cofactor
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

999552:METH RS09580
gene id: 999552:METH_RS09580
uniprot id: V9VQG0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

999552:METH RS20645
gene id: 999552:METH_RS20645
uniprot id: V9VZQ9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS01525
gene id: 999552:METH_RS01525
uniprot id: V9VLX1
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

999552:METH RS07335
gene id: 999552:METH_RS07335
uniprot id: V9VUN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

999552:METH RS18250
gene id: 999552:METH_RS18250
uniprot id: V9VZX6
names: Similarity
messages: Belongs to the GcvT family.

999552:METH RS04310
gene id: 999552:METH_RS04310
uniprot id: V9VRW0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

999552:METH RS04280
gene id: 999552:METH_RS04280
uniprot id: V9VRV8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

999552:METH RS18270
gene id: 999552:METH_RS18270
uniprot id: V9VUN8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

999552:METH RS20435
gene id: 999552:METH_RS20435
uniprot id: V9VXA7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

999552:METH RS05120
gene id: 999552:METH_RS05120
uniprot id: V9VNG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

999552:METH RS06735
gene id: 999552:METH_RS06735
uniprot id: V9VUC3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

999552:METH RS04355
gene id: 999552:METH_RS04355
uniprot id: V9VQV1
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

999552:METH RS13130
gene id: 999552:METH_RS13130
uniprot id: V9VU96
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

999552:METH RS13080
gene id: 999552:METH_RS13080
uniprot id: V9VV46
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS07850
gene id: 999552:METH_RS07850
uniprot id: V9VPN8
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

999552:METH RS05435
gene id: 999552:METH_RS05435
uniprot id: V9VNP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

999552:METH RS20100
gene id: 999552:METH_RS20100
uniprot id: V9VXZ1
names: Similarity
messages: Belongs to the YciI family.

999552:METH RS17580
gene id: 999552:METH_RS17580
uniprot id: V9VZL8
names: Function
names: Similarity
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.

999552:METH RS02010
gene id: 999552:METH_RS02010
uniprot id: V9VPM4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

999552:METH RS09255
gene id: 999552:METH_RS09255
uniprot id: V9VQA8
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS00980
gene id: 999552:METH_RS00980
uniprot id: V9VN81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

999552:METH RS01115
gene id: 999552:METH_RS01115
uniprot id: V9VNA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

999552:METH RS17575
gene id: 999552:METH_RS17575
uniprot id: V9VXM8
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

999552:METH RS20600
gene id: 999552:METH_RS20600
uniprot id: V9W063
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

999552:METH RS18225
gene id: 999552:METH_RS18225
uniprot id: V9VZX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

999552:METH RS11970
gene id: 999552:METH_RS11970
uniprot id: V9VUN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

999552:METH RS15980
gene id: 999552:METH_RS15980
uniprot id: V9VYV7
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

999552:METH RS20050
gene id: 999552:METH_RS20050
uniprot id: V9VZJ6
names: Similarity
messages: Belongs to the LOG family.

999552:METH RS08050
gene id: 999552:METH_RS08050
uniprot id: V9VSM8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

999552:METH RS15855
gene id: 999552:METH_RS15855
uniprot id: V9VXG8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

999552:METH RS19585
gene id: 999552:METH_RS19585
uniprot id: V9W0M4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

999552:METH RS18495
gene id: 999552:METH_RS18495
uniprot id: V9VYP6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

999552:METH RS04060
gene id: 999552:METH_RS04060
uniprot id: V9VRR2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

999552:METH RS19170
gene id: 999552:METH_RS19170
uniprot id: V9W0D4
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

999552:METH RS01200
gene id: 999552:METH_RS01200
uniprot id: V9VQA0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

999552:METH RS20115
gene id: 999552:METH_RS20115
uniprot id: V9VVN0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

999552:METH RS07800
gene id: 999552:METH_RS07800
uniprot id: V9VUV3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

999552:METH RS15570
gene id: 999552:METH_RS15570
uniprot id: V9VYN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

999552:METH RS18870
gene id: 999552:METH_RS18870
uniprot id: V9W072
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

999552:METH RS10965
gene id: 999552:METH_RS10965
uniprot id: V9VWG1
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

999552:METH RS16040
gene id: 999552:METH_RS16040
uniprot id: V9VWK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

999552:METH RS10425
gene id: 999552:METH_RS10425
uniprot id: V9VW75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

999552:METH RS18185
gene id: 999552:METH_RS18185
uniprot id: V9VXK3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

999552:METH RS05045
gene id: 999552:METH_RS05045
uniprot id: V9VNF3
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

999552:METH RS16770
gene id: 999552:METH_RS16770
uniprot id: V9VXV2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

999552:METH RS14225
gene id: 999552:METH_RS14225
uniprot id: V9VY30
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

999552:METH RS13215
gene id: 999552:METH_RS13215
uniprot id: V9VW85
names: Similarity
messages: Belongs to the peptidase A24 family.

999552:METH RS05590
gene id: 999552:METH_RS05590
uniprot id: V9VQN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

999552:METH RS05215
gene id: 999552:METH_RS05215
uniprot id: V9VTP7
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS13910
gene id: 999552:METH_RS13910
uniprot id: V9VXZ9
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS05340
gene id: 999552:METH_RS05340
uniprot id: V9VQJ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Maintains high levels of reduced glutathione.

999552:METH RS11720
gene id: 999552:METH_RS11720
uniprot id: V9VVH2
names: Subcellular Location Annotation
messages: Cell inner membrane

999552:METH RS07865
gene id: 999552:METH_RS07865
uniprot id: V9VSI9
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

999552:METH RS01035
gene id: 999552:METH_RS01035
uniprot id: V9VP54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

999552:METH RS09025
gene id: 999552:METH_RS09025
uniprot id: V9VVH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

999552:METH RS19620
gene id: 999552:METH_RS19620
uniprot id: V9VY98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

999552:METH RS05840
gene id: 999552:METH_RS05840
uniprot id: V9VSR0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

999552:METH RS09065
gene id: 999552:METH_RS09065
uniprot id: V9VT67
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

999552:METH RS05620
gene id: 999552:METH_RS05620
uniprot id: V9VRK5
names: Similarity
messages: Belongs to the TelA family.

999552:METH RS01640
gene id: 999552:METH_RS01640
uniprot id: V9VPF2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

999552:METH RS09620
gene id: 999552:METH_RS09620
uniprot id: V9VTF0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

999552:METH RS14210
gene id: 999552:METH_RS14210
uniprot id: V9VVU3
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS15450
gene id: 999552:METH_RS15450
uniprot id: V9VWD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

999552:METH RS05350
gene id: 999552:METH_RS05350
uniprot id: V9VSI8
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

999552:METH RS00815
gene id: 999552:METH_RS00815
uniprot id: V9VLJ6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS15410
gene id: 999552:METH_RS15410
uniprot id: V9VTD2
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

999552:METH RS11390
gene id: 999552:METH_RS11390
uniprot id: V9VTG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

999552:METH RS09085
gene id: 999552:METH_RS09085
uniprot id: V9VS96
names: Similarity
messages: Belongs to the virb1 family.

999552:METH RS08380
gene id: 999552:METH_RS08380
uniprot id: V9VV50
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

999552:METH RS11115
gene id: 999552:METH_RS11115
uniprot id: V9VU47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

999552:METH RS18460
gene id: 999552:METH_RS18460
uniprot id: V9VXQ2
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

999552:METH RS17420
gene id: 999552:METH_RS17420
uniprot id: V9VY67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

999552:METH RS13050
gene id: 999552:METH_RS13050
uniprot id: V9VU82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

999552:METH RS05380
gene id: 999552:METH_RS05380
uniprot id: V9VNN4
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

999552:METH RS00010
gene id: 999552:METH_RS00010
uniprot id: V9VMU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

999552:METH RS00300
gene id: 999552:METH_RS00300
uniprot id: V9VLC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

999552:METH RS20120
gene id: 999552:METH_RS20120
uniprot id: V9W0W4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

999552:METH RS00220
gene id: 999552:METH_RS00220
uniprot id: V9VR69
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS19205
gene id: 999552:METH_RS19205
uniprot id: V9VY08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

999552:METH RS01570
gene id: 999552:METH_RS01570
uniprot id: V9VQG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

999552:METH RS09755
gene id: 999552:METH_RS09755
uniprot id: V9VSK2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

999552:METH RS07780
gene id: 999552:METH_RS07780
uniprot id: V9VRK6
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS14465
gene id: 999552:METH_RS14465
uniprot id: V9VY68
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

999552:METH RS20660
gene id: 999552:METH_RS20660
uniprot id: V9VXG0
names: Similarity
messages: Belongs to the DapA family.

999552:METH RS13155
gene id: 999552:METH_RS13155
uniprot id: V9VXK9
names: Similarity
messages: Belongs to the transglycosylase Slt family.
messages: Belongs to the virb1 family.

999552:METH RS08390
gene id: 999552:METH_RS08390
uniprot id: V9VSV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

999552:METH RS15380
gene id: 999552:METH_RS15380
uniprot id: V9VX96
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

999552:METH RS12335
gene id: 999552:METH_RS12335
uniprot id: V9VVR0
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

999552:METH RS11925
gene id: 999552:METH_RS11925
uniprot id: V9VVK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein.

999552:METH RS07030
gene id: 999552:METH_RS07030
uniprot id: V9VPA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

999552:METH RS08395
gene id: 999552:METH_RS08395
uniprot id: V9VTY6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS15415
gene id: 999552:METH_RS15415
uniprot id: V9VYK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

999552:METH RS00455
gene id: 999552:METH_RS00455
uniprot id: V9VPW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

999552:METH RS19085
gene id: 999552:METH_RS19085
uniprot id: V9VXD3
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS03550
gene id: 999552:METH_RS03550
uniprot id: V9VQH7
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

999552:METH RS09000
gene id: 999552:METH_RS09000
uniprot id: V9VU81
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

999552:METH RS05440
gene id: 999552:METH_RS05440
uniprot id: V9VTW1
names: Similarity
messages: Belongs to the GST superfamily.

999552:METH RS11610
gene id: 999552:METH_RS11610
uniprot id: V9VTK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

999552:METH RS01085
gene id: 999552:METH_RS01085
uniprot id: V9VRJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

999552:METH RS20840
gene id: 999552:METH_RS20840
uniprot id: V9VZV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

999552:METH RS20855
gene id: 999552:METH_RS20855
uniprot id: V9VXK2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

999552:METH RS19835
gene id: 999552:METH_RS19835
uniprot id: V9W0S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

999552:METH RS01125
gene id: 999552:METH_RS01125
uniprot id: V9VQ86
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

999552:METH RS01670
gene id: 999552:METH_RS01670
uniprot id: V9VQI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

999552:METH RS12680
gene id: 999552:METH_RS12680
uniprot id: V9VUY5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

999552:METH RS18560
gene id: 999552:METH_RS18560
uniprot id: V9W028
names: Function
names: Subcellular Location Annotation
messages: Could be a virulence factor.
messages: Secreted

999552:METH RS17865
gene id: 999552:METH_RS17865
uniprot id: V9VWR1
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

999552:METH RS14220
gene id: 999552:METH_RS14220
uniprot id: V9VST9
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

999552:METH RS18170
gene id: 999552:METH_RS18170
uniprot id: V9VUL8
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

999552:METH RS08600
gene id: 999552:METH_RS08600
uniprot id: V9VQ07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

999552:METH RS01225
gene id: 999552:METH_RS01225
uniprot id: V9VQA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

999552:METH RS15440
gene id: 999552:METH_RS15440
uniprot id: V9VYL3
names: Similarity
messages: Belongs to the TrpF family.

999552:METH RS03320
gene id: 999552:METH_RS03320
uniprot id: V9VPH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

999552:METH RS11620
gene id: 999552:METH_RS11620
uniprot id: V9VVG1
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

999552:METH RS12525
gene id: 999552:METH_RS12525
uniprot id: V9VVU5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

999552:METH RS20005
gene id: 999552:METH_RS20005
uniprot id: V9W0V0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

999552:METH RS09550
gene id: 999552:METH_RS09550
uniprot id: V9VQF6
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

999552:METH RS02610
gene id: 999552:METH_RS02610
uniprot id: V9VSF5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

999552:METH RS14070
gene id: 999552:METH_RS14070
uniprot id: V9VY17
names: Cofactor
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

999552:METH RS05080
gene id: 999552:METH_RS05080
uniprot id: V9VQC7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

999552:METH RS04640
gene id: 999552:METH_RS04640
uniprot id: V9VTC8
names: Subunit
messages: Homotetramer.

999552:METH RS06775
gene id: 999552:METH_RS06775
uniprot id: V9VR29
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS13825
gene id: 999552:METH_RS13825
uniprot id: V9VSK3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

999552:METH RS03100
gene id: 999552:METH_RS03100
uniprot id: V9VPD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

999552:METH RS13085
gene id: 999552:METH_RS13085
uniprot id: V9VW56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

999552:METH RS18115
gene id: 999552:METH_RS18115
uniprot id: V9VYH9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

999552:METH RS21050
gene id: 999552:METH_RS21050
uniprot id: V9W2V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

999552:METH RS14950
gene id: 999552:METH_RS14950
uniprot id: V9VVE3
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS00030
gene id: 999552:METH_RS00030
uniprot id: V9VR37
names: Similarity
messages: Belongs to the SDHAF4 family.

999552:METH RS07535
gene id: 999552:METH_RS07535
uniprot id: V9VUR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

999552:METH RS04525
gene id: 999552:METH_RS04525
uniprot id: V9VTA9
names: Similarity
messages: Belongs to the ClpA/ClpB family.

999552:METH RS11550
gene id: 999552:METH_RS11550
uniprot id: V9VRF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

999552:METH RS19295
gene id: 999552:METH_RS19295
uniprot id: V9W0G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

999552:METH RS06310
gene id: 999552:METH_RS06310
uniprot id: V9VU85
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

999552:METH RS17825
gene id: 999552:METH_RS17825
uniprot id: V9VYD4
names: Similarity
messages: Belongs to the UPF0178 family.

999552:METH RS20015
gene id: 999552:METH_RS20015
uniprot id: V9VXY1
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS09075
gene id: 999552:METH_RS09075
uniprot id: V9VQ80
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

999552:METH RS13290
gene id: 999552:METH_RS13290
uniprot id: V9VWA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

999552:METH RS01920
gene id: 999552:METH_RS01920
uniprot id: V9VPK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

999552:METH RS08400
gene id: 999552:METH_RS08400
uniprot id: V9VPY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

999552:METH RS07615
gene id: 999552:METH_RS07615
uniprot id: V9VUS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

999552:METH RS04050
gene id: 999552:METH_RS04050
uniprot id: V9VPR8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

999552:METH RS06830
gene id: 999552:METH_RS06830
uniprot id: V9VUD8
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

999552:METH RS15805
gene id: 999552:METH_RS15805
uniprot id: V9VXF8
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

999552:METH RS14745
gene id: 999552:METH_RS14745
uniprot id: V9VX01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

999552:METH RS06135
gene id: 999552:METH_RS06135
uniprot id: V9VSU9
names: Subcellular Location Annotation
messages: Cytoplasm

999552:METH RS04450
gene id: 999552:METH_RS04450
uniprot id: V9VT96
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS01625
gene id: 999552:METH_RS01625
uniprot id: V9VLY7
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

999552:METH RS17060
gene id: 999552:METH_RS17060
uniprot id: V9VWD1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

999552:METH RS22405
gene id: 999552:METH_RS22405
uniprot id: V9W2E5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

999552:METH RS09430
gene id: 999552:METH_RS09430
uniprot id: V9VTC1
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS01680
gene id: 999552:METH_RS01680
uniprot id: V9VRV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

999552:METH RS16875
gene id: 999552:METH_RS16875
uniprot id: V9VTZ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

999552:METH RS19230
gene id: 999552:METH_RS19230
uniprot id: V9VY15
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS08430
gene id: 999552:METH_RS08430
uniprot id: V9VPY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

999552:METH RS18955
gene id: 999552:METH_RS18955
uniprot id: V9VXX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

999552:METH RS18745
gene id: 999552:METH_RS18745
uniprot id: V9VUV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

999552:METH RS12795
gene id: 999552:METH_RS12795
uniprot id: V9VS16
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS05825
gene id: 999552:METH_RS05825
uniprot id: V9VU18
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

999552:METH RS13860
gene id: 999552:METH_RS13860
uniprot id: V9VXY0
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

999552:METH RS16050
gene id: 999552:METH_RS16050
uniprot id: V9VTN6
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

999552:METH RS04810
gene id: 999552:METH_RS04810
uniprot id: V9VR24
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

999552:METH RS02700
gene id: 999552:METH_RS02700
uniprot id: V9VQ29
names: Subunit
messages: Homodimer.

999552:METH RS20970
gene id: 999552:METH_RS20970
uniprot id: V9W1D7
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

999552:METH RS07000
gene id: 999552:METH_RS07000
uniprot id: V9VT73
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

999552:METH RS13000
gene id: 999552:METH_RS13000
uniprot id: V9VV33
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

999552:METH RS00430
gene id: 999552:METH_RS00430
uniprot id: V9VPW7
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

999552:METH RS21360
gene id: 999552:METH_RS21360
uniprot id: V9W074
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

999552:METH RS21315
gene id: 999552:METH_RS21315
uniprot id: V9W060
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

999552:METH RS20190
gene id: 999552:METH_RS20190
uniprot id: V9VVP1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

999552:METH RS09035
gene id: 999552:METH_RS09035
uniprot id: V9VT62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

999552:METH RS03715
gene id: 999552:METH_RS03715
uniprot id: V9VPM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

999552:METH RS15620
gene id: 999552:METH_RS15620
uniprot id: V9VTG6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS05420
gene id: 999552:METH_RS05420
uniprot id: V9VQK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

999552:METH RS09750
gene id: 999552:METH_RS09750
uniprot id: V9VVU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

999552:METH RS15605
gene id: 999552:METH_RS15605
uniprot id: V9VWF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

999552:METH RS04795
gene id: 999552:METH_RS04795
uniprot id: V9VNC1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

999552:METH RS17405
gene id: 999552:METH_RS17405
uniprot id: V9VZI3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

999552:METH RS22040
gene id: 999552:METH_RS22040
uniprot id: V9W0S3
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.
messages: Catalyzes the reversible phosphorylation of pyruvate and phosphate.

999552:METH RS16720
gene id: 999552:METH_RS16720
uniprot id: V9VXU4
names: Similarity
messages: Belongs to the DapA family.

999552:METH RS02780
gene id: 999552:METH_RS02780
uniprot id: V9VR67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

999552:METH RS14935
gene id: 999552:METH_RS14935
uniprot id: V9VX27
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

999552:METH RS05635
gene id: 999552:METH_RS05635
uniprot id: V9VTY7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

999552:METH RS18070
gene id: 999552:METH_RS18070
uniprot id: V9VUK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

999552:METH RS06090
gene id: 999552:METH_RS06090
uniprot id: V9VQV9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

999552:METH RS18430
gene id: 999552:METH_RS18430
uniprot id: V9VX06
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

999552:METH RS16340
gene id: 999552:METH_RS16340
uniprot id: V9VWN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

999552:METH RS03510
gene id: 999552:METH_RS03510
uniprot id: V9VMW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

999552:METH RS17750
gene id: 999552:METH_RS17750
uniprot id: V9VYC3
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS19810
gene id: 999552:METH_RS19810
uniprot id: V9W0R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

999552:METH RS08670
gene id: 999552:METH_RS08670
uniprot id: V9VS34
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

999552:METH RS09470
gene id: 999552:METH_RS09470
uniprot id: V9VQE2
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

999552:METH RS20180
gene id: 999552:METH_RS20180
uniprot id: V9VYK7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

999552:METH RS00925
gene id: 999552:METH_RS00925
uniprot id: V9VRG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

999552:METH RS14065
gene id: 999552:METH_RS14065
uniprot id: V9VSS4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS07795
gene id: 999552:METH_RS07795
uniprot id: V9VPM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

999552:METH RS14050
gene id: 999552:METH_RS14050
uniprot id: V9VV34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

999552:METH RS20900
gene id: 999552:METH_RS20900
uniprot id: V9W1C1
names: Similarity
messages: Belongs to the glutamate synthase family.

999552:METH RS12205
gene id: 999552:METH_RS12205
uniprot id: V9VUR9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

999552:METH RS22125
gene id: 999552:METH_RS22125
uniprot id: V9W0W9
names: Subunit
messages: Homodimer.

999552:METH RS07885
gene id: 999552:METH_RS07885
uniprot id: V9VRN0
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

999552:METH RS22020
gene id: 999552:METH_RS22020
uniprot id: V9W3L1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

999552:METH RS10460
gene id: 999552:METH_RS10460
uniprot id: V9VSY1
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

999552:METH RS11640
gene id: 999552:METH_RS11640
uniprot id: V9VUG9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

999552:METH RS11975
gene id: 999552:METH_RS11975
uniprot id: V9VVL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

999552:METH RS13110
gene id: 999552:METH_RS13110
uniprot id: V9VW61
names: Similarity
messages: Belongs to the peptidase U62 family.

999552:METH RS08630
gene id: 999552:METH_RS08630
uniprot id: V9VQ11
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

999552:METH RS00790
gene id: 999552:METH_RS00790
uniprot id: V9VLJ1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

999552:METH RS00985
gene id: 999552:METH_RS00985
uniprot id: V9VP47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

999552:METH RS11260
gene id: 999552:METH_RS11260
uniprot id: V9VWM4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS20605
gene id: 999552:METH_RS20605
uniprot id: V9W176
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

999552:METH RS09520
gene id: 999552:METH_RS09520
uniprot id: V9VQF1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

999552:METH RS12440
gene id: 999552:METH_RS12440
uniprot id: V9VUV0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

999552:METH RS13350
gene id: 999552:METH_RS13350
uniprot id: V9VXP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

999552:METH RS14380
gene id: 999552:METH_RS14380
uniprot id: V9VWV2
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

999552:METH RS12080
gene id: 999552:METH_RS12080
uniprot id: V9VX07
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

999552:METH RS10335
gene id: 999552:METH_RS10335
uniprot id: V9VSV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

999552:METH RS04335
gene id: 999552:METH_RS04335
uniprot id: V9VRW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

999552:METH RS12180
gene id: 999552:METH_RS12180
uniprot id: V9VUR5
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

999552:METH RS18090
gene id: 999552:METH_RS18090
uniprot id: V9VYH4
names: Similarity
messages: Belongs to the peptidase S58 family.

999552:METH RS20665
gene id: 999552:METH_RS20665
uniprot id: V9W2M5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

999552:METH RS10385
gene id: 999552:METH_RS10385
uniprot id: V9VTT4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

999552:METH RS16625
gene id: 999552:METH_RS16625
uniprot id: V9VW43
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

999552:METH RS01550
gene id: 999552:METH_RS01550
uniprot id: V9VLX5
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS16075
gene id: 999552:METH_RS16075
uniprot id: V9VTP1
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

999552:METH RS16710
gene id: 999552:METH_RS16710
uniprot id: V9VW60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

999552:METH RS18380
gene id: 999552:METH_RS18380
uniprot id: V9VWZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

999552:METH RS08220
gene id: 999552:METH_RS08220
uniprot id: V9VSQ7
names: Function
names: Subcellular Location Annotation
messages: Could be a virulence factor.
messages: Secreted

999552:METH RS12760
gene id: 999552:METH_RS12760
uniprot id: V9VUZ7
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

999552:METH RS19160
gene id: 999552:METH_RS19160
uniprot id: V9VZ08
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

999552:METH RS06320
gene id: 999552:METH_RS06320
uniprot id: V9VRX0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

999552:METH RS07320
gene id: 999552:METH_RS07320
uniprot id: V9VSB1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

999552:METH RS12585
gene id: 999552:METH_RS12585
uniprot id: V9VXA2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS17815
gene id: 999552:METH_RS17815
uniprot id: V9VWQ1
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

999552:METH RS08110
gene id: 999552:METH_RS08110
uniprot id: V9VTS2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

999552:METH RS02135
gene id: 999552:METH_RS02135
uniprot id: V9VNT9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS19060
gene id: 999552:METH_RS19060
uniprot id: V9VXC8
names: Similarity
messages: Belongs to the YkuD family.

999552:METH RS06150
gene id: 999552:METH_RS06150
uniprot id: V9VQW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

999552:METH RS04055
gene id: 999552:METH_RS04055
uniprot id: V9VQP6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and hydrogenobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of hydrogenobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CobB catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

999552:METH RS14490
gene id: 999552:METH_RS14490
uniprot id: V9VY73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

999552:METH RS04850
gene id: 999552:METH_RS04850
uniprot id: V9VTH0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

999552:METH RS14035
gene id: 999552:METH_RS14035
uniprot id: V9VY13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

999552:METH RS19950
gene id: 999552:METH_RS19950
uniprot id: V9VVK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

999552:METH RS08130
gene id: 999552:METH_RS08130
uniprot id: V9VSP3
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

999552:METH RS05285
gene id: 999552:METH_RS05285
uniprot id: V9VTT3
names: Function
names: Similarity
messages: Belongs to the nitrile hydratase subunit beta family.
messages: NHase catalyzes the hydration of various nitrile compounds to the corresponding amides.

999552:METH RS12050
gene id: 999552:METH_RS12050
uniprot id: V9VTS6
names: Function
names: Similarity
messages: Belongs to the vsr family.
messages: May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.

999552:METH RS04120
gene id: 999552:METH_RS04120
uniprot id: V9VT32
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

999552:METH RS18420
gene id: 999552:METH_RS18420
uniprot id: V9VUR2
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

999552:METH RS15405
gene id: 999552:METH_RS15405
uniprot id: V9VXA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

999552:METH RS00990
gene id: 999552:METH_RS00990
uniprot id: V9VQ61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

999552:METH RS11945
gene id: 999552:METH_RS11945
uniprot id: V9VUM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

999552:METH RS01515
gene id: 999552:METH_RS01515
uniprot id: V9VPD1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

999552:METH RS19195
gene id: 999552:METH_RS19195
uniprot id: V9W0E0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

999552:METH RS05995
gene id: 999552:METH_RS05995
uniprot id: V9VU41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

999552:METH RS11265
gene id: 999552:METH_RS11265
uniprot id: V9VTE9
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

999552:METH RS19190
gene id: 999552:METH_RS19190
uniprot id: V9VV19
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

999552:METH RS18255
gene id: 999552:METH_RS18255
uniprot id: V9VWX8
names: Similarity
messages: Belongs to the Gfa family.

999552:METH RS18845
gene id: 999552:METH_RS18845
uniprot id: V9VX81
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

999552:METH RS21895
gene id: 999552:METH_RS21895
uniprot id: V9W133
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS06885
gene id: 999552:METH_RS06885
uniprot id: V9VR48
names: Similarity
messages: Belongs to the GST superfamily.

999552:METH RS17710
gene id: 999552:METH_RS17710
uniprot id: V9VZN4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

999552:METH RS18940
gene id: 999552:METH_RS18940
uniprot id: V9VUY4
names: Similarity
messages: Belongs to the UPF0758 family.

999552:METH RS12365
gene id: 999552:METH_RS12365
uniprot id: V9VRU3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

999552:METH RS13430
gene id: 999552:METH_RS13430
uniprot id: V9VSD7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS17415
gene id: 999552:METH_RS17415
uniprot id: V9VX72
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

999552:METH RS14300
gene id: 999552:METH_RS14300
uniprot id: V9VWT9
names: Subunit
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

999552:METH RS08525
gene id: 999552:METH_RS08525
uniprot id: V9VV78
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS02435
gene id: 999552:METH_RS02435
uniprot id: V9VQY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

999552:METH RS02165
gene id: 999552:METH_RS02165
uniprot id: V9VNU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

999552:METH RS06355
gene id: 999552:METH_RS06355
uniprot id: V9VP31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

999552:METH RS11425
gene id: 999552:METH_RS11425
uniprot id: V9VVD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

999552:METH RS18030
gene id: 999552:METH_RS18030
uniprot id: V9VWT8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS12210
gene id: 999552:METH_RS12210
uniprot id: V9VVP3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

999552:METH RS06040
gene id: 999552:METH_RS06040
uniprot id: V9VNZ0
names: Similarity
messages: Belongs to the group II decarboxylase family.

999552:METH RS01915
gene id: 999552:METH_RS01915
uniprot id: V9VNP3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

999552:METH RS18550
gene id: 999552:METH_RS18550
uniprot id: V9VYQ5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

999552:METH RS20950
gene id: 999552:METH_RS20950
uniprot id: V9VXM4
names: Similarity
messages: Belongs to the GcvT family.

999552:METH RS18730
gene id: 999552:METH_RS18730
uniprot id: V9VX62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

999552:METH RS19350
gene id: 999552:METH_RS19350
uniprot id: V9VXI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

999552:METH RS00955
gene id: 999552:METH_RS00955
uniprot id: V9VN75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

999552:METH RS21040
gene id: 999552:METH_RS21040
uniprot id: V9W1F3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

999552:METH RS18740
gene id: 999552:METH_RS18740
uniprot id: V9VYU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

999552:METH RS20105
gene id: 999552:METH_RS20105
uniprot id: V9VYJ5
names: Similarity
messages: Belongs to the AHA1 family.

999552:METH RS07875
gene id: 999552:METH_RS07875
uniprot id: V9VPP3
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS09760
gene id: 999552:METH_RS09760
uniprot id: V9VTH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

999552:METH RS03905
gene id: 999552:METH_RS03905
uniprot id: V9VN10
names: Function
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.

999552:METH RS06265
gene id: 999552:METH_RS06265
uniprot id: V9VQY3
names: Similarity
messages: Belongs to the glutamine synthetase family.

999552:METH RS08465
gene id: 999552:METH_RS08465
uniprot id: V9VPY7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

999552:METH RS05805
gene id: 999552:METH_RS05805
uniprot id: V9VQR7
names: Function
messages: Repressor involved in choline regulation of the bet genes.
messages: Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine.

999552:METH RS21055
gene id: 999552:METH_RS21055
uniprot id: V9W007
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS02410
gene id: 999552:METH_RS02410
uniprot id: V9VMC5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

999552:METH RS11465
gene id: 999552:METH_RS11465
uniprot id: V9VVE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

999552:METH RS12040
gene id: 999552:METH_RS12040
uniprot id: V9VRP0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

999552:METH RS16785
gene id: 999552:METH_RS16785
uniprot id: V9VW76
names: Similarity
messages: Belongs to the Dps family.

999552:METH RS01000
gene id: 999552:METH_RS01000
uniprot id: V9VRI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

999552:METH RS10015
gene id: 999552:METH_RS10015
uniprot id: V9VSQ0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

999552:METH RS08645
gene id: 999552:METH_RS08645
uniprot id: V9VSZ7
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

999552:METH RS15355
gene id: 999552:METH_RS15355
uniprot id: V9VYJ7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

999552:METH RS14915
gene id: 999552:METH_RS14915
uniprot id: V9VT56
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

999552:METH RS05225
gene id: 999552:METH_RS05225
uniprot id: V9VRA8
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

999552:METH RS13260
gene id: 999552:METH_RS13260
uniprot id: V9VV83
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

999552:METH RS02120
gene id: 999552:METH_RS02120
uniprot id: V9VQT0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

999552:METH RS11785
gene id: 999552:METH_RS11785
uniprot id: V9VWW0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

999552:METH RS22395
gene id: 999552:METH_RS22395
uniprot id: V9W3U0
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS14820
gene id: 999552:METH_RS14820
uniprot id: V9VW44
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS14540
gene id: 999552:METH_RS14540
uniprot id: V9VSZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

999552:METH RS10200
gene id: 999552:METH_RS10200
uniprot id: V9VTQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PpiC/parvulin rotamase family.
messages: Cell outer membrane
messages: Membrane

999552:METH RS19005
gene id: 999552:METH_RS19005
uniprot id: V9W099
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

999552:METH RS15500
gene id: 999552:METH_RS15500
uniprot id: V9VTE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

999552:METH RS03540
gene id: 999552:METH_RS03540
uniprot id: V9VSU7
names: Function
names: Similarity
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.

999552:METH RS20315
gene id: 999552:METH_RS20315
uniprot id: V9VZZ8
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

999552:METH RS10470
gene id: 999552:METH_RS10470
uniprot id: V9VUX9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

999552:METH RS09735
gene id: 999552:METH_RS09735
uniprot id: V9VSJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

999552:METH RS16275
gene id: 999552:METH_RS16275
uniprot id: V9VXN2
names: Function
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

999552:METH RS12105
gene id: 999552:METH_RS12105
uniprot id: V9VX12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

999552:METH RS02940
gene id: 999552:METH_RS02940
uniprot id: V9VQ69
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

999552:METH RS09705
gene id: 999552:METH_RS09705
uniprot id: V9VVT1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS07635
gene id: 999552:METH_RS07635
uniprot id: V9VPK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

999552:METH RS15680
gene id: 999552:METH_RS15680
uniprot id: V9VYQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

999552:METH RS19090
gene id: 999552:METH_RS19090
uniprot id: V9VXZ2
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS07820
gene id: 999552:METH_RS07820
uniprot id: V9VTL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

999552:METH RS10150
gene id: 999552:METH_RS10150
uniprot id: V9VTP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

999552:METH RS07645
gene id: 999552:METH_RS07645
uniprot id: V9VRI2
names: Similarity
messages: Belongs to the thioredoxin family. DsbE subfamily.

999552:METH RS12480
gene id: 999552:METH_RS12480
uniprot id: V9VRW1
names: Similarity
messages: Belongs to the UPF0047 family.

999552:METH RS08870
gene id: 999552:METH_RS08870
uniprot id: V9VT34
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

999552:METH RS21440
gene id: 999552:METH_RS21440
uniprot id: V9W094
names: Similarity
messages: Belongs to the RelE toxin family.

999552:METH RS11170
gene id: 999552:METH_RS11170
uniprot id: V9VV90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

999552:METH RS14725
gene id: 999552:METH_RS14725
uniprot id: V9VYA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

999552:METH RS03025
gene id: 999552:METH_RS03025
uniprot id: V9VMQ2
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

999552:METH RS07950
gene id: 999552:METH_RS07950
uniprot id: V9VSK7
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS18675
gene id: 999552:METH_RS18675
uniprot id: V9VXT5
names: Similarity
messages: Belongs to the pirin family.

999552:METH RS20140
gene id: 999552:METH_RS20140
uniprot id: V9VVN4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

999552:METH RS18355
gene id: 999552:METH_RS18355
uniprot id: V9VWZ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

999552:METH RS11715
gene id: 999552:METH_RS11715
uniprot id: V9VUI4
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

999552:METH RS02970
gene id: 999552:METH_RS02970
uniprot id: V9VR94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

999552:METH RS11730
gene id: 999552:METH_RS11730
uniprot id: V9VWV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

999552:METH RS10885
gene id: 999552:METH_RS10885
uniprot id: V9VWE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

999552:METH RS04550
gene id: 999552:METH_RS04550
uniprot id: V9VTB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

999552:METH RS18045
gene id: 999552:METH_RS18045
uniprot id: V9VUJ8
names: Similarity
messages: Belongs to the YggT family.

999552:METH RS12385
gene id: 999552:METH_RS12385
uniprot id: V9VVS0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

999552:METH RS11580
gene id: 999552:METH_RS11580
uniprot id: V9VWS2
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

999552:METH RS12125
gene id: 999552:METH_RS12125
uniprot id: V9VTT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

999552:METH RS13375
gene id: 999552:METH_RS13375
uniprot id: V9VSC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Cell inner membrane
messages: Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP.
messages: Membrane

999552:METH RS08990
gene id: 999552:METH_RS08990
uniprot id: V9VS82
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

999552:METH RS02000
gene id: 999552:METH_RS02000
uniprot id: V9VS15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

999552:METH RS07855
gene id: 999552:METH_RS07855
uniprot id: V9VUW2
names: Similarity
messages: Belongs to the UPF0145 family.

999552:METH RS06965
gene id: 999552:METH_RS06965
uniprot id: V9VR62
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

999552:METH RS05780
gene id: 999552:METH_RS05780
uniprot id: V9VSQ2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS00870
gene id: 999552:METH_RS00870
uniprot id: V9VRF7
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

999552:METH RS18445
gene id: 999552:METH_RS18445
uniprot id: V9VUR6
names: Similarity
messages: Belongs to the peptidase U62 family.

999552:METH RS21595
gene id: 999552:METH_RS21595
uniprot id: V9W0E4
names: Similarity
messages: Belongs to the group II decarboxylase family.

999552:METH RS16670
gene id: 999552:METH_RS16670
uniprot id: V9VTV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

999552:METH RS19535
gene id: 999552:METH_RS19535
uniprot id: V9W0L4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

999552:METH RS20035
gene id: 999552:METH_RS20035
uniprot id: V9W0V4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

999552:METH RS08035
gene id: 999552:METH_RS08035
uniprot id: V9VPS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

999552:METH RS07425
gene id: 999552:METH_RS07425
uniprot id: V9VPG7
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS09995
gene id: 999552:METH_RS09995
uniprot id: V9VTM1
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

999552:METH RS07400
gene id: 999552:METH_RS07400
uniprot id: V9VSC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

999552:METH RS17505
gene id: 999552:METH_RS17505
uniprot id: V9VZK2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS22460
gene id: 999552:METH_RS22460
uniprot id: V9W3V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

999552:METH RS07740
gene id: 999552:METH_RS07740
uniprot id: V9VRJ9
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

999552:METH RS14675
gene id: 999552:METH_RS14675
uniprot id: V9VYA0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

999552:METH RS19920
gene id: 999552:METH_RS19920
uniprot id: V9VZH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

999552:METH RS08640
gene id: 999552:METH_RS08640
uniprot id: V9VS31
names: Similarity
messages: Belongs to the BolA/IbaG family.

999552:METH RS21015
gene id: 999552:METH_RS21015
uniprot id: V9W0G8
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

999552:METH RS02260
gene id: 999552:METH_RS02260
uniprot id: V9VS66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

999552:METH RS13195
gene id: 999552:METH_RS13195
uniprot id: V9VS94
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS13905
gene id: 999552:METH_RS13905
uniprot id: V9VSM4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

999552:METH RS11510
gene id: 999552:METH_RS11510
uniprot id: V9VUE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

999552:METH RS03775
gene id: 999552:METH_RS03775
uniprot id: V9VQK4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

999552:METH RS21155
gene id: 999552:METH_RS21155
uniprot id: V9W1I3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

999552:METH RS13340
gene id: 999552:METH_RS13340
uniprot id: V9VWB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

999552:METH RS04485
gene id: 999552:METH_RS04485
uniprot id: V9VQX2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

999552:METH RS05050
gene id: 999552:METH_RS05050
uniprot id: V9VTL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

999552:METH RS12075
gene id: 999552:METH_RS12075
uniprot id: V9VRP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

999552:METH RS00615
gene id: 999552:METH_RS00615
uniprot id: V9VN20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

999552:METH RS07135
gene id: 999552:METH_RS07135
uniprot id: V9VUJ9
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

999552:METH RS22215
gene id: 999552:METH_RS22215
uniprot id: V9VYL6
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

999552:METH RS03505
gene id: 999552:METH_RS03505
uniprot id: V9VRI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

999552:METH RS13625
gene id: 999552:METH_RS13625
uniprot id: V9VUK8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

999552:METH RS04265
gene id: 999552:METH_RS04265
uniprot id: V9VT61
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

999552:METH RS20700
gene id: 999552:METH_RS20700
uniprot id: V9W190
names: Similarity
messages: Belongs to the ParB family.

999552:METH RS00735
gene id: 999552:METH_RS00735
uniprot id: V9VN37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

999552:METH RS06370
gene id: 999552:METH_RS06370
uniprot id: V9VRX8
names: Similarity
messages: Belongs to the Gfa family.

999552:METH RS00875
gene id: 999552:METH_RS00875
uniprot id: V9VN60
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

999552:METH RS04760
gene id: 999552:METH_RS04760
uniprot id: V9VS42
names: Similarity
messages: Belongs to the PhzF family.

999552:METH RS19175
gene id: 999552:METH_RS19175
uniprot id: V9VXE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

999552:METH RS21465
gene id: 999552:METH_RS21465
uniprot id: V9W0S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

999552:METH RS00775
gene id: 999552:METH_RS00775
uniprot id: V9VP11
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

999552:METH RS04115
gene id: 999552:METH_RS04115
uniprot id: V9VN30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

999552:METH RS16025
gene id: 999552:METH_RS16025
uniprot id: V9VTN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

999552:METH RS03260
gene id: 999552:METH_RS03260
uniprot id: V9VSQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

999552:METH RS19010
gene id: 999552:METH_RS19010
uniprot id: V9VXB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

999552:METH RS20490
gene id: 999552:METH_RS20490
uniprot id: V9W038
names: Subcellular Location Annotation
messages: Cell inner membrane

999552:METH RS13845
gene id: 999552:METH_RS13845
uniprot id: V9VVK1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS01180
gene id: 999552:METH_RS01180
uniprot id: V9VLS1
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

999552:METH RS10880
gene id: 999552:METH_RS10880
uniprot id: V9VR15
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS09090
gene id: 999552:METH_RS09090
uniprot id: V9VT71
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

999552:METH RS05150
gene id: 999552:METH_RS05150
uniprot id: V9VTN4
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

999552:METH RS15950
gene id: 999552:METH_RS15950
uniprot id: V9VTL6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

999552:METH RS09740
gene id: 999552:METH_RS09740
uniprot id: V9VUL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

999552:METH RS16610
gene id: 999552:METH_RS16610
uniprot id: V9VXS5
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

999552:METH RS19840
gene id: 999552:METH_RS19840
uniprot id: V9VXS8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

999552:METH RS15970
gene id: 999552:METH_RS15970
uniprot id: V9VXI6
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

999552:METH RS21500
gene id: 999552:METH_RS21500
uniprot id: V9VXY8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS15795
gene id: 999552:METH_RS15795
uniprot id: V9VVR2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

999552:METH RS11690
gene id: 999552:METH_RS11690
uniprot id: V9VUH9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

999552:METH RS17720
gene id: 999552:METH_RS17720
uniprot id: V9VXB5
names: Similarity
messages: Belongs to the group II decarboxylase family.

999552:METH RS10080
gene id: 999552:METH_RS10080
uniprot id: V9VQP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

999552:METH RS00750
gene id: 999552:METH_RS00750
uniprot id: V9VQ20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

999552:METH RS15540
gene id: 999552:METH_RS15540
uniprot id: V9VWE7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

999552:METH RS20425
gene id: 999552:METH_RS20425
uniprot id: V9W024
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

999552:METH RS01165
gene id: 999552:METH_RS01165
uniprot id: V9VNB6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

999552:METH RS07005
gene id: 999552:METH_RS07005
uniprot id: V9VPA1
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS03295
gene id: 999552:METH_RS03295
uniprot id: V9VPG6
names: Similarity
messages: Belongs to the autoinducer synthase family.

999552:METH RS22150
gene id: 999552:METH_RS22150
uniprot id: V9W0X4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

999552:METH RS03455
gene id: 999552:METH_RS03455
uniprot id: V9VRH5
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

999552:METH RS14735
gene id: 999552:METH_RS14735
uniprot id: V9VW31
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

999552:METH RS00645
gene id: 999552:METH_RS00645
uniprot id: V9VNY5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

999552:METH RS00295
gene id: 999552:METH_RS00295
uniprot id: V9VPV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

999552:METH RS00315
gene id: 999552:METH_RS00315
uniprot id: V9VNT2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.

999552:METH RS14715
gene id: 999552:METH_RS14715
uniprot id: V9VWZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

999552:METH RS01105
gene id: 999552:METH_RS01105
uniprot id: V9VLQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

999552:METH RS09895
gene id: 999552:METH_RS09895
uniprot id: V9VQL6
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

999552:METH RS01080
gene id: 999552:METH_RS01080
uniprot id: V9VLQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

999552:METH RS18175
gene id: 999552:METH_RS18175
uniprot id: V9VZW2
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.
messages: Membrane

999552:METH RS13995
gene id: 999552:METH_RS13995
uniprot id: V9VSR6
names: Similarity
messages: Belongs to the universal stress protein A family.

999552:METH RS00135
gene id: 999552:METH_RS00135
uniprot id: V9VR55
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

999552:METH RS05155
gene id: 999552:METH_RS05155
uniprot id: V9VQE3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

999552:METH RS08790
gene id: 999552:METH_RS08790
uniprot id: V9VT20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

999552:METH RS06010
gene id: 999552:METH_RS06010
uniprot id: V9VST2
names: Similarity
messages: Belongs to the YjdM family.

999552:METH RS07920
gene id: 999552:METH_RS07920
uniprot id: V9VRN5
names: Similarity
messages: Belongs to the YkuD family.

999552:METH RS14145
gene id: 999552:METH_RS14145
uniprot id: V9VVT9
names: Similarity
messages: Belongs to the DDAH family.

999552:METH RS07130
gene id: 999552:METH_RS07130
uniprot id: V9VPC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

999552:METH RS19715
gene id: 999552:METH_RS19715
uniprot id: V9VZB9
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

999552:METH RS08565
gene id: 999552:METH_RS08565
uniprot id: V9VU19
names: Similarity
messages: Belongs to the citrate synthase family.

999552:METH RS05295
gene id: 999552:METH_RS05295
uniprot id: V9VRF1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

999552:METH RS09290
gene id: 999552:METH_RS09290
uniprot id: V9VVL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COX15/CtaA family. Type 2 subfamily.
messages: Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
messages: Cell membrane
messages: Interacts with CtaB.
messages: Membrane

999552:METH RS11725
gene id: 999552:METH_RS11725
uniprot id: V9VRI5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

999552:METH RS11915
gene id: 999552:METH_RS11915
uniprot id: V9VTQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

999552:METH RS07105
gene id: 999552:METH_RS07105
uniprot id: V9VPB7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SoxA family.
messages: Binds 2 heme groups per subunit.
messages: Heterodimer of SoxA and SoxX.
messages: Periplasm

999552:METH RS08535
gene id: 999552:METH_RS08535
uniprot id: V9VSX9
names: Similarity
messages: Belongs to the TrpC family.

999552:METH RS09425
gene id: 999552:METH_RS09425
uniprot id: V9VSE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

999552:METH RS03485
gene id: 999552:METH_RS03485
uniprot id: V9VMV9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

999552:METH RS12780
gene id: 999552:METH_RS12780
uniprot id: V9VU39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

999552:METH RS09965
gene id: 999552:METH_RS09965
uniprot id: V9VSP0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

999552:METH RS13200
gene id: 999552:METH_RS13200
uniprot id: V9VXL8
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS17525
gene id: 999552:METH_RS17525
uniprot id: V9VUA7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

999552:METH RS19665
gene id: 999552:METH_RS19665
uniprot id: V9W0N9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

999552:METH RS17745
gene id: 999552:METH_RS17745
uniprot id: V9VXB8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS12625
gene id: 999552:METH_RS12625
uniprot id: V9VVW4
names: Similarity
messages: Belongs to the RecJ family.

999552:METH RS08695
gene id: 999552:METH_RS08695
uniprot id: V9VS40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

999552:METH RS00575
gene id: 999552:METH_RS00575
uniprot id: V9VPZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

999552:METH RS16270
gene id: 999552:METH_RS16270
uniprot id: V9VWN0
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

999552:METH RS11955
gene id: 999552:METH_RS11955
uniprot id: V9VRM7
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS08735
gene id: 999552:METH_RS08735
uniprot id: V9VT10
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

999552:METH RS13075
gene id: 999552:METH_RS13075
uniprot id: V9VU86
names: Similarity
messages: Belongs to the threonine synthase family.

999552:METH RS02885
gene id: 999552:METH_RS02885
uniprot id: V9VPA8
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

999552:METH RS00485
gene id: 999552:METH_RS00485
uniprot id: V9VR98
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

999552:METH RS19420
gene id: 999552:METH_RS19420
uniprot id: V9VV60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

999552:METH RS13985
gene id: 999552:METH_RS13985
uniprot id: V9VVR6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

999552:METH RS19215
gene id: 999552:METH_RS19215
uniprot id: V9VV22
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

999552:METH RS21215
gene id: 999552:METH_RS21215
uniprot id: V9W2Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

999552:METH RS03050
gene id: 999552:METH_RS03050
uniprot id: V9VSM1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS12020
gene id: 999552:METH_RS12020
uniprot id: V9VUP0
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

999552:METH RS09530
gene id: 999552:METH_RS09530
uniprot id: V9VVP8
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

999552:METH RS22095
gene id: 999552:METH_RS22095
uniprot id: V9W3P3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS13630
gene id: 999552:METH_RS13630
uniprot id: V9VVH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

999552:METH RS21000
gene id: 999552:METH_RS21000
uniprot id: V9VXN4
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

999552:METH RS21715
gene id: 999552:METH_RS21715
uniprot id: V9W0H8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS21665
gene id: 999552:METH_RS21665
uniprot id: V9W3A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

999552:METH RS19180
gene id: 999552:METH_RS19180
uniprot id: V9VY04
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

999552:METH RS03580
gene id: 999552:METH_RS03580
uniprot id: V9VQI0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

999552:METH RS00635
gene id: 999552:METH_RS00635
uniprot id: V9VRC2
names: Similarity
messages: Belongs to the YkuD family.

999552:METH RS18435
gene id: 999552:METH_RS18435
uniprot id: V9VXP9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

999552:METH RS06880
gene id: 999552:METH_RS06880
uniprot id: V9VUF0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

999552:METH RS22380
gene id: 999552:METH_RS22380
uniprot id: V9W121
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

999552:METH RS06725
gene id: 999552:METH_RS06725
uniprot id: V9VT23
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS07605
gene id: 999552:METH_RS07605
uniprot id: V9VTH8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

999552:METH RS00765
gene id: 999552:METH_RS00765
uniprot id: V9VRD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

999552:METH RS07165
gene id: 999552:METH_RS07165
uniprot id: V9VR99
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

999552:METH RS12380
gene id: 999552:METH_RS12380
uniprot id: V9VUU2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

999552:METH RS06890
gene id: 999552:METH_RS06890
uniprot id: V9VS35
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

999552:METH RS12300
gene id: 999552:METH_RS12300
uniprot id: V9VTV6
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

999552:METH RS10290
gene id: 999552:METH_RS10290
uniprot id: V9VTR7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

999552:METH RS18725
gene id: 999552:METH_RS18725
uniprot id: V9W054
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

999552:METH RS05180
gene id: 999552:METH_RS05180
uniprot id: V9VTN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

999552:METH RS09545
gene id: 999552:METH_RS09545
uniprot id: V9VUH0
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

999552:METH RS14510
gene id: 999552:METH_RS14510
uniprot id: V9VSY9
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

999552:METH RS13250
gene id: 999552:METH_RS13250
uniprot id: V9VXM8
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

999552:METH RS12990
gene id: 999552:METH_RS12990
uniprot id: V9VXI2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

999552:METH RS07455
gene id: 999552:METH_RS07455
uniprot id: V9VUQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

999552:METH RS20980
gene id: 999552:METH_RS20980
uniprot id: V9W2U0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS14560
gene id: 999552:METH_RS14560
uniprot id: V9VWX7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS08045
gene id: 999552:METH_RS08045
uniprot id: V9VRR6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS13355
gene id: 999552:METH_RS13355
uniprot id: V9VUE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

999552:METH RS14385
gene id: 999552:METH_RS14385
uniprot id: V9VSW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

999552:METH RS18235
gene id: 999552:METH_RS18235
uniprot id: V9VXL0
names: Similarity
messages: Belongs to the GcvT family.

999552:METH RS18415
gene id: 999552:METH_RS18415
uniprot id: V9VYN2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

999552:METH RS16985
gene id: 999552:METH_RS16985
uniprot id: V9VWA7
names: Similarity
messages: Belongs to the YciI family.

999552:METH RS15810
gene id: 999552:METH_RS15810
uniprot id: V9VTJ3
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

999552:METH RS19015
gene id: 999552:METH_RS19015
uniprot id: V9VXX8
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

999552:METH RS11855
gene id: 999552:METH_RS11855
uniprot id: V9VRL0
names: Similarity
messages: Belongs to the BolA/IbaG family.

999552:METH RS04165
gene id: 999552:METH_RS04165
uniprot id: V9VT42
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS01140
gene id: 999552:METH_RS01140
uniprot id: V9VNB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

999552:METH RS03365
gene id: 999552:METH_RS03365
uniprot id: V9VSR8
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

999552:METH RS21475
gene id: 999552:METH_RS21475
uniprot id: V9VXY2
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

999552:METH RS15130
gene id: 999552:METH_RS15130
uniprot id: V9VYG6
names: Similarity
messages: Belongs to the peptidase C40 family.

999552:METH RS11295
gene id: 999552:METH_RS11295
uniprot id: V9VUB4
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

999552:METH RS04405
gene id: 999552:METH_RS04405
uniprot id: V9VQW1
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS09135
gene id: 999552:METH_RS09135
uniprot id: V9VU97
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

999552:METH RS14885
gene id: 999552:METH_RS14885
uniprot id: V9VX20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

999552:METH RS21905
gene id: 999552:METH_RS21905
uniprot id: V9VYA4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

999552:METH RS19675
gene id: 999552:METH_RS19675
uniprot id: V9VXP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

999552:METH RS03000
gene id: 999552:METH_RS03000
uniprot id: V9VMQ0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

999552:METH RS14575
gene id: 999552:METH_RS14575
uniprot id: V9VY85
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS19825
gene id: 999552:METH_RS19825
uniprot id: V9VZD9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

999552:METH RS01575
gene id: 999552:METH_RS01575
uniprot id: V9VLY0
names: Similarity
messages: Belongs to the UPF0102 family.

999552:METH RS14780
gene id: 999552:METH_RS14780
uniprot id: V9VT31
names: Subcellular Location Annotation
messages: Cell inner membrane

999552:METH RS11320
gene id: 999552:METH_RS11320
uniprot id: V9VUC1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS19990
gene id: 999552:METH_RS19990
uniprot id: V9VYI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

999552:METH RS17540
gene id: 999552:METH_RS17540
uniprot id: V9VX91
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

999552:METH RS19955
gene id: 999552:METH_RS19955
uniprot id: V9W0U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

999552:METH RS05665
gene id: 999552:METH_RS05665
uniprot id: V9VQP3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

999552:METH RS03175
gene id: 999552:METH_RS03175
uniprot id: V9VMS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

999552:METH RS00320
gene id: 999552:METH_RS00320
uniprot id: V9VPV8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

999552:METH RS10420
gene id: 999552:METH_RS10420
uniprot id: V9VQV3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

999552:METH RS13415
gene id: 999552:METH_RS13415
uniprot id: V9VUG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0283 family.
messages: Cell inner membrane
messages: Membrane

999552:METH RS05705
gene id: 999552:METH_RS05705
uniprot id: V9VSP1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS19745
gene id: 999552:METH_RS19745
uniprot id: V9VYB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

999552:METH RS19750
gene id: 999552:METH_RS19750
uniprot id: V9VZC3
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

999552:METH RS11560
gene id: 999552:METH_RS11560
uniprot id: V9VTJ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

999552:METH RS00855
gene id: 999552:METH_RS00855
uniprot id: V9VP25
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

999552:METH RS07995
gene id: 999552:METH_RS07995
uniprot id: V9VRQ5
names: Similarity
messages: Belongs to the YicC/YloC family.

999552:METH RS02800
gene id: 999552:METH_RS02800
uniprot id: V9VP98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

999552:METH RS12315
gene id: 999552:METH_RS12315
uniprot id: V9VRT3
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

999552:METH RS13535
gene id: 999552:METH_RS13535
uniprot id: V9VXT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P-Pant transferase superfamily. EntD family.
messages: EntB, EntD, EntE, and EntF form a multienzyme complex called enterobactin synthase.
messages: Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo-domains of both EntB (ArCP domain) and EntF (PCP domain) to yield their holo-forms which make them competent for the activation of 2,3-dihydroxybenzoate (DHB) and L-serine, respectively.

999552:METH RS09950
gene id: 999552:METH_RS09950
uniprot id: V9VUQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

999552:METH RS01545
gene id: 999552:METH_RS01545
uniprot id: V9VQF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

999552:METH RS01210
gene id: 999552:METH_RS01210
uniprot id: V9VRM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

999552:METH RS10060
gene id: 999552:METH_RS10060
uniprot id: V9VVZ9
names: Similarity
messages: Belongs to the SufE family.

999552:METH RS07775
gene id: 999552:METH_RS07775
uniprot id: V9VUU9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

999552:METH RS12965
gene id: 999552:METH_RS12965
uniprot id: V9VXH6
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

999552:METH RS05600
gene id: 999552:METH_RS05600
uniprot id: V9VSM6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

999552:METH RS04695
gene id: 999552:METH_RS04695
uniprot id: V9VTD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

999552:METH RS03515
gene id: 999552:METH_RS03515
uniprot id: V9VSU2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

999552:METH RS00665
gene id: 999552:METH_RS00665
uniprot id: V9VRC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

999552:METH RS16600
gene id: 999552:METH_RS16600
uniprot id: V9VW37
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

999552:METH RS19260
gene id: 999552:METH_RS19260
uniprot id: V9VZ30
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

999552:METH RS01725
gene id: 999552:METH_RS01725
uniprot id: V9VM04
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

999552:METH RS19960
gene id: 999552:METH_RS19960
uniprot id: V9VXX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

999552:METH RS11270
gene id: 999552:METH_RS11270
uniprot id: V9VUA9
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

999552:METH RS05580
gene id: 999552:METH_RS05580
uniprot id: V9VNR8
names: Subcellular Location Annotation
messages: Cell inner membrane

999552:METH RS00865
gene id: 999552:METH_RS00865
uniprot id: V9VLK7
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

999552:METH RS08235
gene id: 999552:METH_RS08235
uniprot id: V9VPW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

999552:METH RS02935
gene id: 999552:METH_RS02935
uniprot id: V9VPB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

999552:METH RS05055
gene id: 999552:METH_RS05055
uniprot id: V9VQC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

999552:METH RS04820
gene id: 999552:METH_RS04820
uniprot id: V9VNC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

999552:METH RS08560
gene id: 999552:METH_RS08560
uniprot id: V9VSY3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

999552:METH RS18925
gene id: 999552:METH_RS18925
uniprot id: V9VX99
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

999552:METH RS06275
gene id: 999552:METH_RS06275
uniprot id: V9VSX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

999552:METH RS16230
gene id: 999552:METH_RS16230
uniprot id: V9VWT1
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS04085
gene id: 999552:METH_RS04085
uniprot id: V9VRR7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

999552:METH RS18970
gene id: 999552:METH_RS18970
uniprot id: V9W095
names: Similarity
messages: Belongs to the Nudix hydrolase family.

999552:METH RS22480
gene id: 999552:METH_RS22480
uniprot id: V9VYT3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS22115
gene id: 999552:METH_RS22115
uniprot id: V9VYH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

999552:METH RS03155
gene id: 999552:METH_RS03155
uniprot id: V9VSN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

999552:METH RS12005
gene id: 999552:METH_RS12005
uniprot id: V9VRN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

999552:METH RS09295
gene id: 999552:METH_RS09295
uniprot id: V9VSC4
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

999552:METH RS06270
gene id: 999552:METH_RS06270
uniprot id: V9VRV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

999552:METH RS22290
gene id: 999552:METH_RS22290
uniprot id: V9VYN4
names: Similarity
messages: Belongs to the VgrG protein family.

999552:METH RS21255
gene id: 999552:METH_RS21255
uniprot id: V9W1K9
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

999552:METH RS14920
gene id: 999552:METH_RS14920
uniprot id: V9VYE0
names: Similarity
messages: Belongs to the PhoH family.

999552:METH RS12475
gene id: 999552:METH_RS12475
uniprot id: V9VVT4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

999552:METH RS01605
gene id: 999552:METH_RS01605
uniprot id: V9VRU4
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

999552:METH RS04700
gene id: 999552:METH_RS04700
uniprot id: V9VQ44
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

999552:METH RS04920
gene id: 999552:METH_RS04920
uniprot id: V9VND6
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

999552:METH RS02790
gene id: 999552:METH_RS02790
uniprot id: V9VML5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

999552:METH RS10020
gene id: 999552:METH_RS10020
uniprot id: V9VTM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

999552:METH RS12950
gene id: 999552:METH_RS12950
uniprot id: V9VV23
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS08040
gene id: 999552:METH_RS08040
uniprot id: V9VUZ1
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

999552:METH RS12620
gene id: 999552:METH_RS12620
uniprot id: V9VUX8
names: Similarity
messages: Belongs to the FBPase class 2 family.

999552:METH RS05475
gene id: 999552:METH_RS05475
uniprot id: V9VQL5
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

999552:METH RS12130
gene id: 999552:METH_RS12130
uniprot id: V9VUQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

999552:METH RS09250
gene id: 999552:METH_RS09250
uniprot id: V9VUB6
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

999552:METH RS10230
gene id: 999552:METH_RS10230
uniprot id: V9VUU3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

999552:METH RS07630
gene id: 999552:METH_RS07630
uniprot id: V9VTI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

999552:METH RS07010
gene id: 999552:METH_RS07010
uniprot id: V9VUH5
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

999552:METH RS21250
gene id: 999552:METH_RS21250
uniprot id: V9W0M3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

999552:METH RS03220
gene id: 999552:METH_RS03220
uniprot id: V9VRD4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

999552:METH RS08495
gene id: 999552:METH_RS08495
uniprot id: V9VPZ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
messages: Cell membrane
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.

999552:METH RS19475
gene id: 999552:METH_RS19475
uniprot id: V9VZ77
names: Similarity
messages: Belongs to the glutamate synthase family.

999552:METH RS15510
gene id: 999552:METH_RS15510
uniprot id: V9VVM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

999552:METH RS19590
gene id: 999552:METH_RS19590
uniprot id: V9VXN0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

999552:METH RS22375
gene id: 999552:METH_RS22375
uniprot id: V9W3T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

999552:METH RS08545
gene id: 999552:METH_RS08545
uniprot id: V9VPZ8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

999552:METH RS01360
gene id: 999552:METH_RS01360
uniprot id: V9VLV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

999552:METH RS02065
gene id: 999552:METH_RS02065
uniprot id: V9VPN3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

999552:METH RS15600
gene id: 999552:METH_RS15600
uniprot id: V9VVN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

999552:METH RS14305
gene id: 999552:METH_RS14305
uniprot id: V9VSV2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

999552:METH RS02500
gene id: 999552:METH_RS02500
uniprot id: V9VSC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

999552:METH RS03145
gene id: 999552:METH_RS03145
uniprot id: V9VMR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

999552:METH RS10960
gene id: 999552:METH_RS10960
uniprot id: V9VR30
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

999552:METH RS02005
gene id: 999552:METH_RS02005
uniprot id: V9VNR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

999552:METH RS19235
gene id: 999552:METH_RS19235
uniprot id: V9VZ24
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS03165
gene id: 999552:METH_RS03165
uniprot id: V9VQB2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

999552:METH RS17495
gene id: 999552:METH_RS17495
uniprot id: V9VY82
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

999552:METH RS00070
gene id: 999552:METH_RS00070
uniprot id: V9VPS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

999552:METH RS22445
gene id: 999552:METH_RS22445
uniprot id: V9W137
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

999552:METH RS20415
gene id: 999552:METH_RS20415
uniprot id: V9W2G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

999552:METH RS09245
gene id: 999552:METH_RS09245
uniprot id: V9VT93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

999552:METH RS20690
gene id: 999552:METH_RS20690
uniprot id: V9VZR8
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

999552:METH RS06100
gene id: 999552:METH_RS06100
uniprot id: V9VRT1
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

999552:METH RS11750
gene id: 999552:METH_RS11750
uniprot id: V9VRJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

999552:METH RS13305
gene id: 999552:METH_RS13305
uniprot id: V9VUD5
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

999552:METH RS09355
gene id: 999552:METH_RS09355
uniprot id: V9VUD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

999552:METH RS11905
gene id: 999552:METH_RS11905
uniprot id: V9VRL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

999552:METH RS00170
gene id: 999552:METH_RS00170
uniprot id: V9VR59
names: Subunit
messages: Monomer.

999552:METH RS22475
gene id: 999552:METH_RS22475
uniprot id: V9W2G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

999552:METH RS02670
gene id: 999552:METH_RS02670
uniprot id: V9VP73
names: Similarity
messages: Belongs to the peptidase S11 family.

999552:METH RS18035
gene id: 999552:METH_RS18035
uniprot id: V9VXH0
names: Similarity
messages: Belongs to the UPF0246 family.

999552:METH RS18755
gene id: 999552:METH_RS18755
uniprot id: V9VX67
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

999552:METH RS13855
gene id: 999552:METH_RS13855
uniprot id: V9VSL0
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

999552:METH RS10330
gene id: 999552:METH_RS10330
uniprot id: V9VW50
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

999552:METH RS07610
gene id: 999552:METH_RS07610
uniprot id: V9VPK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

999552:METH RS15610
gene id: 999552:METH_RS15610
uniprot id: V9VXD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

999552:METH RS12320
gene id: 999552:METH_RS12320
uniprot id: V9VX43
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

999552:METH RS15395
gene id: 999552:METH_RS15395
uniprot id: V9VVK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

999552:METH RS17980
gene id: 999552:METH_RS17980
uniprot id: V9VWS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

999552:METH RS09840
gene id: 999552:METH_RS09840
uniprot id: V9VQK7
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS20850
gene id: 999552:METH_RS20850
uniprot id: V9W1B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

999552:METH RS04555
gene id: 999552:METH_RS04555
uniprot id: V9VQ13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

999552:METH RS05695
gene id: 999552:METH_RS05695
uniprot id: V9VQP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

999552:METH RS09285
gene id: 999552:METH_RS09285
uniprot id: V9VQB3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

999552:METH RS00755
gene id: 999552:METH_RS00755
uniprot id: V9VLI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

999552:METH RS04300
gene id: 999552:METH_RS04300
uniprot id: V9VQU2
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

999552:METH RS13295
gene id: 999552:METH_RS13295
uniprot id: V9VSB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

999552:METH RS19140
gene id: 999552:METH_RS19140
uniprot id: V9W0C9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

999552:METH RS19305
gene id: 999552:METH_RS19305
uniprot id: V9VY29
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

999552:METH RS13720
gene id: 999552:METH_RS13720
uniprot id: V9VXW0
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

999552:METH RS01370
gene id: 999552:METH_RS01370
uniprot id: V9VNF9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

999552:METH RS01760
gene id: 999552:METH_RS01760
uniprot id: V9VNL4
names: Subcellular Location Annotation
messages: Cytoplasm

999552:METH RS10040
gene id: 999552:METH_RS10040
uniprot id: V9VSQ3
names: Similarity
messages: Belongs to the acylphosphatase family.

999552:METH RS01440
gene id: 999552:METH_RS01440
uniprot id: V9VQE5
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

999552:METH RS10160
gene id: 999552:METH_RS10160
uniprot id: V9VQQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

999552:METH RS13275
gene id: 999552:METH_RS13275
uniprot id: V9VXN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

999552:METH RS03780
gene id: 999552:METH_RS03780
uniprot id: V9VRM2
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

999552:METH RS15815
gene id: 999552:METH_RS15815
uniprot id: V9VYS5
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

999552:METH RS04730
gene id: 999552:METH_RS04730
uniprot id: V9VR11
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

999552:METH RS01290
gene id: 999552:METH_RS01290
uniprot id: V9VNE5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

999552:METH RS08845
gene id: 999552:METH_RS08845
uniprot id: V9VT29
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

999552:METH RS00255
gene id: 999552:METH_RS00255
uniprot id: V9VNS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

999552:METH RS07595
gene id: 999552:METH_RS07595
uniprot id: V9VRG9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS18125
gene id: 999552:METH_RS18125
uniprot id: V9VZV2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

999552:METH RS20730
gene id: 999552:METH_RS20730
uniprot id: V9VXH5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS03605
gene id: 999552:METH_RS03605
uniprot id: V9VQI5
names: Similarity
messages: Belongs to the GcvT family.

999552:METH RS18205
gene id: 999552:METH_RS18205
uniprot id: V9VWW9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

999552:METH RS10555
gene id: 999552:METH_RS10555
uniprot id: V9VTW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

999552:METH RS06990
gene id: 999552:METH_RS06990
uniprot id: V9VR68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

999552:METH RS10415
gene id: 999552:METH_RS10415
uniprot id: V9VUX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

999552:METH RS03190
gene id: 999552:METH_RS03190
uniprot id: V9VQB7
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

999552:METH RS14095
gene id: 999552:METH_RS14095
uniprot id: V9VSS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NosZ family.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.
messages: Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide.
messages: Periplasm

999552:METH RS02820
gene id: 999552:METH_RS02820
uniprot id: V9VSI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

999552:METH RS04985
gene id: 999552:METH_RS04985
uniprot id: V9VR63
names: Similarity
messages: Belongs to the phosphohexose mutase family.

999552:METH RS14020
gene id: 999552:METH_RS14020
uniprot id: V9VVR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

999552:METH RS05320
gene id: 999552:METH_RS05320
uniprot id: V9VRF6
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

999552:METH RS13320
gene id: 999552:METH_RS13320
uniprot id: V9VSB8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

999552:METH RS11180
gene id: 999552:METH_RS11180
uniprot id: V9VWL4
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

999552:METH RS08860
gene id: 999552:METH_RS08860
uniprot id: V9VVD3
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

999552:METH RS12880
gene id: 999552:METH_RS12880
uniprot id: V9VS32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

999552:METH RS14655
gene id: 999552:METH_RS14655
uniprot id: V9VVA4
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

999552:METH RS01090
gene id: 999552:METH_RS01090
uniprot id: V9VNA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

999552:METH RS02605
gene id: 999552:METH_RS02605
uniprot id: V9VMI7
names: Similarity
messages: Belongs to the universal stress protein A family.

999552:METH RS17715
gene id: 999552:METH_RS17715
uniprot id: V9VWN2
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

999552:METH RS19505
gene id: 999552:METH_RS19505
uniprot id: V9VV76
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS15920
gene id: 999552:METH_RS15920
uniprot id: V9VXH7
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

999552:METH RS00655
gene id: 999552:METH_RS00655
uniprot id: V9VLH3
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

999552:METH RS05255
gene id: 999552:METH_RS05255
uniprot id: V9VNI5
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

999552:METH RS08080
gene id: 999552:METH_RS08080
uniprot id: V9VSN2
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

999552:METH RS09910
gene id: 999552:METH_RS09910
uniprot id: V9VTK6
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS05815
gene id: 999552:METH_RS05815
uniprot id: V9VSQ6
names: Similarity
messages: Belongs to the sulfatase family.

999552:METH RS19945
gene id: 999552:METH_RS19945
uniprot id: V9VZI0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

999552:METH RS01555
gene id: 999552:METH_RS01555
uniprot id: V9VRT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

999552:METH RS19030
gene id: 999552:METH_RS19030
uniprot id: V9W0A5
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

999552:METH RS18575
gene id: 999552:METH_RS18575
uniprot id: V9VUT6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

999552:METH RS13240
gene id: 999552:METH_RS13240
uniprot id: V9VW89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

999552:METH RS05585
gene id: 999552:METH_RS05585
uniprot id: V9VTX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

999552:METH RS06130
gene id: 999552:METH_RS06130
uniprot id: V9VRT7
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

999552:METH RS12015
gene id: 999552:METH_RS12015
uniprot id: V9VTS3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

999552:METH RS01425
gene id: 999552:METH_RS01425
uniprot id: V9VRR5
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

999552:METH RS17100
gene id: 999552:METH_RS17100
uniprot id: V9VY32
names: Similarity
messages: Belongs to the GcvT family.

999552:METH RS08225
gene id: 999552:METH_RS08225
uniprot id: V9VTU2
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS13090
gene id: 999552:METH_RS13090
uniprot id: V9VS73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

999552:METH RS11395
gene id: 999552:METH_RS11395
uniprot id: V9VUD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

999552:METH RS20790
gene id: 999552:METH_RS20790
uniprot id: V9VZU2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

999552:METH RS11980
gene id: 999552:METH_RS11980
uniprot id: V9VRN1
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS06995
gene id: 999552:METH_RS06995
uniprot id: V9VS53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

999552:METH RS09610
gene id: 999552:METH_RS09610
uniprot id: V9VVQ9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

999552:METH RS17015
gene id: 999552:METH_RS17015
uniprot id: V9VWB3
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

999552:METH RS18905
gene id: 999552:METH_RS18905
uniprot id: V9VXW1
names: Similarity
messages: Belongs to the UDPGP type 2 family.

999552:METH RS04460
gene id: 999552:METH_RS04460
uniprot id: V9VQW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

999552:METH RS19555
gene id: 999552:METH_RS19555
uniprot id: V9VV86
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

999552:METH RS09590
gene id: 999552:METH_RS09590
uniprot id: V9VSG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

999552:METH RS18020
gene id: 999552:METH_RS18020
uniprot id: V9VUJ2
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

999552:METH RS16725
gene id: 999552:METH_RS16725
uniprot id: V9VTW7
names: Similarity
messages: Belongs to the proline racemase family.

999552:METH RS02155
gene id: 999552:METH_RS02155
uniprot id: V9VM83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

999552:METH RS08090
gene id: 999552:METH_RS08090
uniprot id: V9VPT3
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS08745
gene id: 999552:METH_RS08745
uniprot id: V9VQ28
names: Similarity
messages: Belongs to the HIBADH-related family.

999552:METH RS04900
gene id: 999552:METH_RS04900
uniprot id: V9VTI0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS01840
gene id: 999552:METH_RS01840
uniprot id: V9VNM5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS09810
gene id: 999552:METH_RS09810
uniprot id: V9VTI7
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

999552:METH RS11340
gene id: 999552:METH_RS11340
uniprot id: V9VTG4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

999552:METH RS09320
gene id: 999552:METH_RS09320
uniprot id: V9VSC8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

999552:METH RS14525
gene id: 999552:METH_RS14525
uniprot id: V9VW02
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

999552:METH RS10935
gene id: 999552:METH_RS10935
uniprot id: V9VR23
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

999552:METH RS10190
gene id: 999552:METH_RS10190
uniprot id: V9VW18
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS11670
gene id: 999552:METH_RS11670
uniprot id: V9VVG5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

999552:METH RS05455
gene id: 999552:METH_RS05455
uniprot id: V9VSK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

999552:METH RS00115
gene id: 999552:METH_RS00115
uniprot id: V9VMV5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

999552:METH RS17900
gene id: 999552:METH_RS17900
uniprot id: V9VYE7
names: Cofactor
messages: Binds 1 zinc ion per subunit.

999552:METH RS18960
gene id: 999552:METH_RS18960
uniprot id: V9VYX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PpiC/parvulin rotamase family.
messages: Cell outer membrane
messages: Membrane

999552:METH RS02905
gene id: 999552:METH_RS02905
uniprot id: V9VSJ5
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

999552:METH RS01275
gene id: 999552:METH_RS01275
uniprot id: V9VQB4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS10025
gene id: 999552:METH_RS10025
uniprot id: V9VUR3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

999552:METH RS00700
gene id: 999552:METH_RS00700
uniprot id: V9VRD0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

999552:METH RS20155
gene id: 999552:METH_RS20155
uniprot id: V9VYK4
names: Subcellular Location Annotation
messages: Cytoplasm

999552:METH RS19200
gene id: 999552:METH_RS19200
uniprot id: V9VXF3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

999552:METH RS01150
gene id: 999552:METH_RS01150
uniprot id: V9VQ91
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

999552:METH RS20080
gene id: 999552:METH_RS20080
uniprot id: V9VYJ1
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

999552:METH RS12195
gene id: 999552:METH_RS12195
uniprot id: V9VX24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS07815
gene id: 999552:METH_RS07815
uniprot id: V9VSI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

999552:METH RS19095
gene id: 999552:METH_RS19095
uniprot id: V9VZ00
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

999552:METH RS15515
gene id: 999552:METH_RS15515
uniprot id: V9VWE4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

999552:METH RS09725
gene id: 999552:METH_RS09725
uniprot id: V9VQI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

999552:METH RS12615
gene id: 999552:METH_RS12615
uniprot id: V9VU11
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

999552:METH RS10210
gene id: 999552:METH_RS10210
uniprot id: V9VQR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

999552:METH RS06730
gene id: 999552:METH_RS06730
uniprot id: V9VP58
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde.

999552:METH RS04540
gene id: 999552:METH_RS04540
uniprot id: V9VS02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

999552:METH RS03920
gene id: 999552:METH_RS03920
uniprot id: V9VQN0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

999552:METH RS17775
gene id: 999552:METH_RS17775
uniprot id: V9VYC7
names: Similarity
messages: Belongs to the peptidase C40 family.

999552:METH RS12435
gene id: 999552:METH_RS12435
uniprot id: V9VTX8
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

999552:METH RS12225
gene id: 999552:METH_RS12225
uniprot id: V9VTU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

999552:METH RS18180
gene id: 999552:METH_RS18180
uniprot id: V9VWW6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapB family.
messages: Binds 2 heme C groups per subunit.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Electron transfer subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from the membrane-anchored tetraheme c-type NapC protein and transfers these to NapA subunit, thus allowing electron flow between membrane and periplasm. Essential for periplasmic nitrate reduction with nitrate as the terminal electron acceptor.
messages: Periplasm

999552:METH RS05750
gene id: 999552:METH_RS05750
uniprot id: V9VRM6
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS14670
gene id: 999552:METH_RS14670
uniprot id: V9VT12
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

999552:METH RS19595
gene id: 999552:METH_RS19595
uniprot id: V9VY92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

999552:METH RS18595
gene id: 999552:METH_RS18595
uniprot id: V9VYR6
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS03620
gene id: 999552:METH_RS03620
uniprot id: V9VSW1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

999552:METH RS13315
gene id: 999552:METH_RS13315
uniprot id: V9VWA9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

999552:METH RS13115
gene id: 999552:METH_RS13115
uniprot id: V9VS79
names: Similarity
messages: Belongs to the DprA/Smf family.

999552:METH RS05730
gene id: 999552:METH_RS05730
uniprot id: V9VSP6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

999552:METH RS11345
gene id: 999552:METH_RS11345
uniprot id: V9VUC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

999552:METH RS21770
gene id: 999552:METH_RS21770
uniprot id: V9W0J7
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

999552:METH RS09635
gene id: 999552:METH_RS09635
uniprot id: V9VVR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

999552:METH RS04445
gene id: 999552:METH_RS04445
uniprot id: V9VN80
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS10560
gene id: 999552:METH_RS10560
uniprot id: V9VUZ0
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

999552:METH RS03480
gene id: 999552:METH_RS03480
uniprot id: V9VRI0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

999552:METH RS09865
gene id: 999552:METH_RS09865
uniprot id: V9VUN6
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

999552:METH RS21045
gene id: 999552:METH_RS21045
uniprot id: V9VXP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

999552:METH RS02705
gene id: 999552:METH_RS02705
uniprot id: V9VR56
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

999552:METH RS02375
gene id: 999552:METH_RS02375
uniprot id: V9VPU5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

999552:METH RS00965
gene id: 999552:METH_RS00965
uniprot id: V9VQ56
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

999552:METH RS04275
gene id: 999552:METH_RS04275
uniprot id: V9VQT7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

999552:METH RS19385
gene id: 999552:METH_RS19385
uniprot id: V9VZ58
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

999552:METH RS01450
gene id: 999552:METH_RS01450
uniprot id: V9VRR9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

999552:METH RS09210
gene id: 999552:METH_RS09210
uniprot id: V9VUB2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS19850
gene id: 999552:METH_RS19850
uniprot id: V9VZE4
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body

999552:METH RS10300
gene id: 999552:METH_RS10300
uniprot id: V9VQS8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.

999552:METH RS14580
gene id: 999552:METH_RS14580
uniprot id: V9VV98
names: Similarity
messages: Belongs to the LacAB/RpiB family.

999552:METH RS10995
gene id: 999552:METH_RS10995
uniprot id: V9VR33
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

999552:METH RS14005
gene id: 999552:METH_RS14005
uniprot id: V9VV31
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

999552:METH RS20880
gene id: 999552:METH_RS20880
uniprot id: V9VXK7
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS08585
gene id: 999552:METH_RS08585
uniprot id: V9VS23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

999552:METH RS05490
gene id: 999552:METH_RS05490
uniprot id: V9VSK8
names: Similarity
messages: Belongs to the aspartokinase family.

999552:METH RS11075
gene id: 999552:METH_RS11075
uniprot id: V9VWH9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS08060
gene id: 999552:METH_RS08060
uniprot id: V9VTR1
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

999552:METH RS11695
gene id: 999552:METH_RS11695
uniprot id: V9VVG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

999552:METH RS04425
gene id: 999552:METH_RS04425
uniprot id: V9VT91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

999552:METH RS18410
gene id: 999552:METH_RS18410
uniprot id: V9VXP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

999552:METH RS09030
gene id: 999552:METH_RS09030
uniprot id: V9VS87
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

999552:METH RS16015
gene id: 999552:METH_RS16015
uniprot id: V9VWK2
names: Similarity
messages: Belongs to the IucA/IucC family.

999552:METH RS14500
gene id: 999552:METH_RS14500
uniprot id: V9VVZ7
names: Similarity
messages: Belongs to the MlaA family.

999552:METH RS18135
gene id: 999552:METH_RS18135
uniprot id: V9VXJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

999552:METH RS18120
gene id: 999552:METH_RS18120
uniprot id: V9VUK9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

999552:METH RS11845
gene id: 999552:METH_RS11845
uniprot id: V9VUK7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

999552:METH RS07845
gene id: 999552:METH_RS07845
uniprot id: V9VTM0
names: Function
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

999552:METH RS21710
gene id: 999552:METH_RS21710
uniprot id: V9W3C0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
messages: Homodimer.
messages: Involved in phosphonate degradation.

999552:METH RS09475
gene id: 999552:METH_RS09475
uniprot id: V9VVP0
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Belongs to the IspF family.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS12650
gene id: 999552:METH_RS12650
uniprot id: V9VU15
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

999552:METH RS18110
gene id: 999552:METH_RS18110
uniprot id: V9VXI8
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

999552:METH RS18145
gene id: 999552:METH_RS18145
uniprot id: V9VUL3
names: Subcellular Location Annotation
messages: Cell inner membrane

999552:METH RS07395
gene id: 999552:METH_RS07395
uniprot id: V9VRD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

999552:METH RS12770
gene id: 999552:METH_RS12770
uniprot id: V9VS11
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

999552:METH RS02105
gene id: 999552:METH_RS02105
uniprot id: V9VS38
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

999552:METH RS18140
gene id: 999552:METH_RS18140
uniprot id: V9VYI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

999552:METH RS18330
gene id: 999552:METH_RS18330
uniprot id: V9VWZ0
names: Similarity
messages: Belongs to the UPF0434 family.

999552:METH RS22070
gene id: 999552:METH_RS22070
uniprot id: V9W3M8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

999552:METH RS20165
gene id: 999552:METH_RS20165
uniprot id: V9VVN8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

999552:METH RS08485
gene id: 999552:METH_RS08485
uniprot id: V9VSW8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS11900
gene id: 999552:METH_RS11900
uniprot id: V9VVJ5
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

999552:METH RS17585
gene id: 999552:METH_RS17585
uniprot id: V9VWL5
names: Similarity
messages: Belongs to the glutamate synthase family.

999552:METH RS20895
gene id: 999552:METH_RS20895
uniprot id: V9W0D7
names: Similarity
messages: Belongs to the TPP enzyme family.

999552:METH RS16400
gene id: 999552:METH_RS16400
uniprot id: V9VW11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

999552:METH RS00795
gene id: 999552:METH_RS00795
uniprot id: V9VRE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

999552:METH RS09890
gene id: 999552:METH_RS09890
uniprot id: V9VUP1
names: Similarity
messages: Belongs to the CFA/CMAS family.

999552:METH RS13635
gene id: 999552:METH_RS13635
uniprot id: V9VWG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

999552:METH RS06380
gene id: 999552:METH_RS06380
uniprot id: V9VP34
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

999552:METH RS04030
gene id: 999552:METH_RS04030
uniprot id: V9VPR3
names: Function
messages: Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A.

999552:METH RS08575
gene id: 999552:METH_RS08575
uniprot id: V9VQ03
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

999552:METH RS16945
gene id: 999552:METH_RS16945
uniprot id: V9VXX7
names: Similarity
messages: Belongs to the pirin family.

999552:METH RS12725
gene id: 999552:METH_RS12725
uniprot id: V9VU29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. L-carnitine dehydrogenase subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3-dehydrocarnitine.
messages: Cytoplasm
messages: Homodimer.

999552:METH RS03555
gene id: 999552:METH_RS03555
uniprot id: V9VRJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

999552:METH RS09455
gene id: 999552:METH_RS09455
uniprot id: V9VSE6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

999552:METH RS11615
gene id: 999552:METH_RS11615
uniprot id: V9VUG6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

999552:METH RS07505
gene id: 999552:METH_RS07505
uniprot id: V9VSD4
names: Similarity
messages: Belongs to the GcvT family.

999552:METH RS05735
gene id: 999552:METH_RS05735
uniprot id: V9VNU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

999552:METH RS06365
gene id: 999552:METH_RS06365
uniprot id: V9VQZ8
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

999552:METH RS09005
gene id: 999552:METH_RS09005
uniprot id: V9VQ73
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

999552:METH RS08490
gene id: 999552:METH_RS08490
uniprot id: V9VU03
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

999552:METH RS03030
gene id: 999552:METH_RS03030
uniprot id: V9VSL8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

999552:METH RS20125
gene id: 999552:METH_RS20125
uniprot id: V9VXZ5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

999552:METH RS22420
gene id: 999552:METH_RS22420
uniprot id: V9W132
names: Subcellular Location Annotation
messages: Cell membrane

999552:METH RS20915
gene id: 999552:METH_RS20915
uniprot id: V9W0E2
names: Similarity
messages: Belongs to the GST superfamily.

999552:METH RS10410
gene id: 999552:METH_RS10410
uniprot id: V9VTT8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

999552:METH RS05740
gene id: 999552:METH_RS05740
uniprot id: V9VU04
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

999552:METH RS09675
gene id: 999552:METH_RS09675
uniprot id: V9VUJ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

999552:METH RS07935
gene id: 999552:METH_RS07935
uniprot id: V9VPQ3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

999552:METH RS19690
gene id: 999552:METH_RS19690
uniprot id: V9VZB5
names: Caution
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS13175
gene id: 999552:METH_RS13175
uniprot id: V9VXL4
names: Similarity
messages: Belongs to the bacterial secretin family.

999552:METH RS16125
gene id: 999552:METH_RS16125
uniprot id: V9VWL6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

999552:METH RS01015
gene id: 999552:METH_RS01015
uniprot id: V9VQ67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

999552:METH RS03735
gene id: 999552:METH_RS03735
uniprot id: V9VSX2
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

999552:METH RS17090
gene id: 999552:METH_RS17090
uniprot id: V9VWF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

999552:METH RS07405
gene id: 999552:METH_RS07405
uniprot id: V9VTE6
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

999552:METH RS15895
gene id: 999552:METH_RS15895
uniprot id: V9VXH3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

999552:METH RS07245
gene id: 999552:METH_RS07245
uniprot id: V9VSA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

999552:METH RS11780
gene id: 999552:METH_RS11780
uniprot id: V9VRJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.

999552:METH RS11910
gene id: 999552:METH_RS11910
uniprot id: V9VWY2
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

999552:METH RS01620
gene id: 999552:METH_RS01620
uniprot id: V9VQH2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS19410
gene id: 999552:METH_RS19410
uniprot id: V9VY52
names: Subcellular Location Annotation
messages: Nucleus

999552:METH RS17820
gene id: 999552:METH_RS17820
uniprot id: V9VXD2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

999552:METH RS18325
gene id: 999552:METH_RS18325
uniprot id: V9VZZ1
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

999552:METH RS00650
gene id: 999552:METH_RS00650
uniprot id: V9VQ04
names: Caution
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

999552:METH RS03760
gene id: 999552:METH_RS03760
uniprot id: V9VMZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

999552:METH RS10910
gene id: 999552:METH_RS10910
uniprot id: V9VWE9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.
messages: Membrane

999552:METH RS08840
gene id: 999552:METH_RS08840
uniprot id: V9VS58
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

999552:METH RS14690
gene id: 999552:METH_RS14690
uniprot id: V9VWZ2
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

999552:METH RS14420
gene id: 999552:METH_RS14420
uniprot id: V9VV77
names: Similarity
messages: Belongs to the SfsA family.

999552:METH RS03345
gene id: 999552:METH_RS03345
uniprot id: V9VPH4
names: Similarity
messages: Belongs to the BMP lipoprotein family.

999552:METH RS09790
gene id: 999552:METH_RS09790
uniprot id: V9VUM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

999552:METH RS02865
gene id: 999552:METH_RS02865
uniprot id: V9VQ57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

999552:METH RS20710
gene id: 999552:METH_RS20710
uniprot id: V9W2N5
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS01790
gene id: 999552:METH_RS01790
uniprot id: V9VNL7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

999552:METH RS09045
gene id: 999552:METH_RS09045
uniprot id: V9VQ77
names: Subcellular Location Annotation
messages: Cell membrane

999552:METH RS07050
gene id: 999552:METH_RS07050
uniprot id: V9VT85
names: Similarity
messages: Belongs to the TPP enzyme family.

999552:METH RS09880
gene id: 999552:METH_RS09880
uniprot id: V9VSM7
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

999552:METH RS05235
gene id: 999552:METH_RS05235
uniprot id: V9VSE1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

999552:METH RS03315
gene id: 999552:METH_RS03315
uniprot id: V9VSQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

999552:METH RS20470
gene id: 999552:METH_RS20470
uniprot id: V9W152
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

999552:METH RS00950
gene id: 999552:METH_RS00950
uniprot id: V9VRH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

999552:METH RS09795
gene id: 999552:METH_RS09795
uniprot id: V9VQJ7
names: Subcellular Location Annotation
messages: Cell inner membrane

999552:METH RS08760
gene id: 999552:METH_RS08760
uniprot id: V9VT15
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

999552:METH RS09480
gene id: 999552:METH_RS09480
uniprot id: V9VSF0
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

999552:METH RS07600
gene id: 999552:METH_RS07600
uniprot id: V9VSE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

999552:METH RS08705
gene id: 999552:METH_RS08705
uniprot id: V9VU36
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS18155
gene id: 999552:METH_RS18155
uniprot id: V9VWW1
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

999552:METH RS04505
gene id: 999552:METH_RS04505
uniprot id: V9VQ01
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

999552:METH RS00270
gene id: 999552:METH_RS00270
uniprot id: V9VR75
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

999552:METH RS12325
gene id: 999552:METH_RS12325
uniprot id: V9VTW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

999552:METH RS05760
gene id: 999552:METH_RS05760
uniprot id: V9VNU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

999552:METH RS17510
gene id: 999552:METH_RS17510
uniprot id: V9VWK4
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

999552:METH RS13135
gene id: 999552:METH_RS13135
uniprot id: V9VV54
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

999552:METH RS02540
gene id: 999552:METH_RS02540
uniprot id: V9VR25
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

999552:METH RS21785
gene id: 999552:METH_RS21785
uniprot id: V9W3E4
names: Similarity
messages: Belongs to the histone deacetylase family.

999552:METH RS01770
gene id: 999552:METH_RS01770
uniprot id: V9VQK0
names: Similarity
messages: Belongs to the thioredoxin family.

999552:METH RS19125
gene id: 999552:METH_RS19125
uniprot id: V9VV10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

999552:METH RS19325
gene id: 999552:METH_RS19325
uniprot id: V9VXH9
names: Similarity
messages: Belongs to the thioredoxin family.

999552:METH RS07870
gene id: 999552:METH_RS07870
uniprot id: V9VTM6
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

999552:METH RS21340
gene id: 999552:METH_RS21340
uniprot id: V9W0P4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

999552:METH RS15245
gene id: 999552:METH_RS15245
uniprot id: V9VVI0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

999552:METH RS00940
gene id: 999552:METH_RS00940
uniprot id: V9VQ51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

999552:METH RS21210
gene id: 999552:METH_RS21210
uniprot id: V9VXT2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

999552:METH RS19820
gene id: 999552:METH_RS19820
uniprot id: V9VYD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

999552:METH RS09720
gene id: 999552:METH_RS09720
uniprot id: V9VUK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

999552:METH RS17360
gene id: 999552:METH_RS17360
uniprot id: V9VU79
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

999552:METH RS02340
gene id: 999552:METH_RS02340
uniprot id: V9VS83
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

999552:METH RS08530
gene id: 999552:METH_RS08530
uniprot id: V9VS13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

999552:METH RS19255
gene id: 999552:METH_RS19255
uniprot id: V9VY18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

999552:METH RS07200
gene id: 999552:METH_RS07200
uniprot id: V9VTB2
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS19165
gene id: 999552:METH_RS19165
uniprot id: V9VV14
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

999552:METH RS00035
gene id: 999552:METH_RS00035
uniprot id: V9VMU8
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS08165
gene id: 999552:METH_RS08165
uniprot id: V9VTT1
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS17515
gene id: 999552:METH_RS17515
uniprot id: V9VX87
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

999552:METH RS08440
gene id: 999552:METH_RS08440
uniprot id: V9VS01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

999552:METH RS14000
gene id: 999552:METH_RS14000
uniprot id: V9VY10
names: Similarity
messages: Belongs to the GcvT family.

999552:METH RS02565
gene id: 999552:METH_RS02565
uniprot id: V9VR28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

999552:METH RS00905
gene id: 999552:METH_RS00905
uniprot id: V9VLN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

999552:METH RS09630
gene id: 999552:METH_RS09630
uniprot id: V9VQG6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

999552:METH RS14025
gene id: 999552:METH_RS14025
uniprot id: V9VWP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

999552:METH RS00995
gene id: 999552:METH_RS00995
uniprot id: V9VLN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

999552:METH RS02295
gene id: 999552:METH_RS02295
uniprot id: V9VPS8
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

999552:METH RS02600
gene id: 999552:METH_RS02600
uniprot id: V9VR34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

999552:METH RS00960
gene id: 999552:METH_RS00960
uniprot id: V9VP42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

999552:METH RS00745
gene id: 999552:METH_RS00745
uniprot id: V9VP04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

999552:METH RS18750
gene id: 999552:METH_RS18750
uniprot id: V9W058
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

999552:METH RS03850
gene id: 999552:METH_RS03850
uniprot id: V9VN05
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS10225
gene id: 999552:METH_RS10225
uniprot id: V9VTQ9
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

999552:METH RS11300
gene id: 999552:METH_RS11300
uniprot id: V9VVC3
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS19425
gene id: 999552:METH_RS19425
uniprot id: V9W0J4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

999552:METH RS05655
gene id: 999552:METH_RS05655
uniprot id: V9VNT0
names: Similarity
messages: Belongs to the UPF0173 family.

999552:METH RS02380
gene id: 999552:METH_RS02380
uniprot id: V9VQX3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS21995
gene id: 999552:METH_RS21995
uniprot id: V9VYC8
names: Similarity
messages: Belongs to the universal stress protein A family.

999552:METH RS17470
gene id: 999552:METH_RS17470
uniprot id: V9VY76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS11895
gene id: 999552:METH_RS11895
uniprot id: V9VUL7
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS01155
gene id: 999552:METH_RS01155
uniprot id: V9VLR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

999552:METH RS10990
gene id: 999552:METH_RS10990
uniprot id: V9VV45
names: Function
names: Similarity
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: May be required for disulfide bond formation in some proteins.

999552:METH RS04770
gene id: 999552:METH_RS04770
uniprot id: V9VTF3
names: Caution
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS04270
gene id: 999552:METH_RS04270
uniprot id: V9VPW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

999552:METH RS02920
gene id: 999552:METH_RS02920
uniprot id: V9VR87
names: Similarity
messages: Belongs to the Nudix hydrolase family.

999552:METH RS05170
gene id: 999552:METH_RS05170
uniprot id: V9VSD1
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

999552:METH RS12820
gene id: 999552:METH_RS12820
uniprot id: V9VS20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

999552:METH RS20755
gene id: 999552:METH_RS20755
uniprot id: V9VXI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

999552:METH RS01890
gene id: 999552:METH_RS01890
uniprot id: V9VNN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

999552:METH RS16470
gene id: 999552:METH_RS16470
uniprot id: V9VZ31
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

999552:METH RS00895
gene id: 999552:METH_RS00895
uniprot id: V9VRG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

999552:METH RS18720
gene id: 999552:METH_RS18720
uniprot id: V9VUV5
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

999552:METH RS12520
gene id: 999552:METH_RS12520
uniprot id: V9VUW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

999552:METH RS04440
gene id: 999552:METH_RS04440
uniprot id: V9VRY0
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS07665
gene id: 999552:METH_RS07665
uniprot id: V9VPK9
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

999552:METH RS10490
gene id: 999552:METH_RS10490
uniprot id: V9VTV1
names: Similarity
messages: Belongs to the HesB/IscA family.

999552:METH RS03215
gene id: 999552:METH_RS03215
uniprot id: V9VQC1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

999552:METH RS01710
gene id: 999552:METH_RS01710
uniprot id: V9VNK5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS03495
gene id: 999552:METH_RS03495
uniprot id: V9VPJ8
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

999552:METH RS00565
gene id: 999552:METH_RS00565
uniprot id: V9VN12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

999552:METH RS05970
gene id: 999552:METH_RS05970
uniprot id: V9VQU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

999552:METH RS00685
gene id: 999552:METH_RS00685
uniprot id: V9VNZ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

999552:METH RS19815
gene id: 999552:METH_RS19815
uniprot id: V9VXS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

999552:METH RS16975
gene id: 999552:METH_RS16975
uniprot id: V9VU07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

999552:METH RS00580
gene id: 999552:METH_RS00580
uniprot id: V9VLG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

999552:METH RS17455
gene id: 999552:METH_RS17455
uniprot id: V9VZJ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

999552:METH RS20185
gene id: 999552:METH_RS20185
uniprot id: V9VZL9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

999552:METH RS17520
gene id: 999552:METH_RS17520
uniprot id: V9VY86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

999552:METH RS16415
gene id: 999552:METH_RS16415
uniprot id: V9VTS4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS01315
gene id: 999552:METH_RS01315
uniprot id: V9VRP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

999552:METH RS10570
gene id: 999552:METH_RS10570
uniprot id: V9VWA0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

999552:METH RS03130
gene id: 999552:METH_RS03130
uniprot id: V9VQA7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

999552:METH RS19830
gene id: 999552:METH_RS19830
uniprot id: V9VVE9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

999552:METH RS13120
gene id: 999552:METH_RS13120
uniprot id: V9VXK4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

999552:METH RS06720
gene id: 999552:METH_RS06720
uniprot id: V9VS05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

999552:METH RS01430
gene id: 999552:METH_RS01430
uniprot id: V9VNG6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS04435
gene id: 999552:METH_RS04435
uniprot id: V9VQW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

999552:METH RS04725
gene id: 999552:METH_RS04725
uniprot id: V9VQ49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

999552:METH RS11740
gene id: 999552:METH_RS11740
uniprot id: V9VUI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

999552:METH RS09040
gene id: 999552:METH_RS09040
uniprot id: V9VU83
names: Similarity
messages: Belongs to the fabD family.

999552:METH RS01170
gene id: 999552:METH_RS01170
uniprot id: V9VP77
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

999552:METH RS11590
gene id: 999552:METH_RS11590
uniprot id: V9VUG2
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.

999552:METH RS14840
gene id: 999552:METH_RS14840
uniprot id: V9VVC8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

999552:METH RS02335
gene id: 999552:METH_RS02335
uniprot id: V9VMA9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

999552:METH RS11130
gene id: 999552:METH_RS11130
uniprot id: V9VWJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

999552:METH RS01580
gene id: 999552:METH_RS01580
uniprot id: V9VRT9
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

999552:METH RS01665
gene id: 999552:METH_RS01665
uniprot id: V9VPF8
names: Similarity
messages: Belongs to the MreC family.

999552:METH RS15635
gene id: 999552:METH_RS15635
uniprot id: V9VWF7
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

999552:METH RS11755
gene id: 999552:METH_RS11755
uniprot id: V9VWV5
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

999552:METH RS09660
gene id: 999552:METH_RS09660
uniprot id: V9VVS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

999552:METH RS07825
gene id: 999552:METH_RS07825
uniprot id: V9VPN4
names: Subunit
messages: Homodimer.

999552:METH RS21095
gene id: 999552:METH_RS21095
uniprot id: V9W018
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

999552:METH RS13380
gene id: 999552:METH_RS13380
uniprot id: V9VXQ3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

999552:METH RS05335
gene id: 999552:METH_RS05335
uniprot id: V9VTU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

999552:METH RS05105
gene id: 999552:METH_RS05105
uniprot id: V9VQD2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS12190
gene id: 999552:METH_RS12190
uniprot id: V9VRR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

999552:METH RS19925
gene id: 999552:METH_RS19925
uniprot id: V9VVJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

999552:METH RS18770
gene id: 999552:METH_RS18770
uniprot id: V9VYU8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

999552:METH RS19225
gene id: 999552:METH_RS19225
uniprot id: V9VXF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

999552:METH RS11110
gene id: 999552:METH_RS11110
uniprot id: V9VT95
names: Similarity
messages: Belongs to the HesB/IscA family.

999552:METH RS21190
gene id: 999552:METH_RS21190
uniprot id: V9VXS6
names: Similarity
messages: Belongs to the class-C beta-lactamase family.

999552:METH RS04840
gene id: 999552:METH_RS04840
uniprot id: V9VS60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

999552:METH RS00520
gene id: 999552:METH_RS00520
uniprot id: V9VNW0
names: Similarity
messages: Belongs to the PRORSD1 family.

999552:METH RS00510
gene id: 999552:METH_RS00510
uniprot id: V9VRA1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cell inner membrane
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

999552:METH RS15505
gene id: 999552:METH_RS15505
uniprot id: V9VYM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

999552:METH RS08550
gene id: 999552:METH_RS08550
uniprot id: V9VV82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

999552:METH RS18490
gene id: 999552:METH_RS18490
uniprot id: V9VXQ7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

999552:METH RS18230
gene id: 999552:METH_RS18230
uniprot id: V9VWX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

999552:METH RS00145
gene id: 999552:METH_RS00145
uniprot id: V9VNQ2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

999552:METH RS17605
gene id: 999552:METH_RS17605
uniprot id: V9VZM1
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS10895
gene id: 999552:METH_RS10895
uniprot id: V9VU12
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

999552:METH RS15675
gene id: 999552:METH_RS15675
uniprot id: V9VTH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

999552:METH RS08555
gene id: 999552:METH_RS08555
uniprot id: V9VS18
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS08000
gene id: 999552:METH_RS08000
uniprot id: V9VSL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

999552:METH RS04625
gene id: 999552:METH_RS04625
uniprot id: V9VQZ3
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

999552:METH RS21345
gene id: 999552:METH_RS21345
uniprot id: V9W1N3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

999552:METH RS15790
gene id: 999552:METH_RS15790
uniprot id: V9VYR8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS19615
gene id: 999552:METH_RS19615
uniprot id: V9VXN5
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

999552:METH RS19655
gene id: 999552:METH_RS19655
uniprot id: V9VZA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

999552:METH RS10340
gene id: 999552:METH_RS10340
uniprot id: V9VTS5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS01190
gene id: 999552:METH_RS01190
uniprot id: V9VNC3
names: Function
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

999552:METH RS10000
gene id: 999552:METH_RS10000
uniprot id: V9VUQ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

999552:METH RS05520
gene id: 999552:METH_RS05520
uniprot id: V9VNQ9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

999552:METH RS02415
gene id: 999552:METH_RS02415
uniprot id: V9VS98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

999552:METH RS04645
gene id: 999552:METH_RS04645
uniprot id: V9VQ31
names: Similarity
messages: Belongs to the UPF0260 family.

999552:METH RS19480
gene id: 999552:METH_RS19480
uniprot id: V9VV71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

999552:METH RS03855
gene id: 999552:METH_RS03855
uniprot id: V9VSZ2
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS06285
gene id: 999552:METH_RS06285
uniprot id: V9VU80
names: Similarity
messages: Belongs to the ABC transporter superfamily.

999552:METH RS19185
gene id: 999552:METH_RS19185
uniprot id: V9VZ14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

999552:METH RS03095
gene id: 999552:METH_RS03095
uniprot id: V9VRB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

999552:METH RS14115
gene id: 999552:METH_RS14115
uniprot id: V9VV39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane

999552:METH RS22370
gene id: 999552:METH_RS22370
uniprot id: V9VYQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

999552:METH RS13070
gene id: 999552:METH_RS13070
uniprot id: V9VXJ4
names: Similarity
messages: Belongs to the peptidase M16 family.

999552:METH RS06945
gene id: 999552:METH_RS06945
uniprot id: V9VT63
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

999552:METH RS10315
gene id: 999552:METH_RS10315
uniprot id: V9VTS1
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

999552:METH RS02300
gene id: 999552:METH_RS02300
uniprot id: V9VQW0
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

999552:METH RS18525
gene id: 999552:METH_RS18525
uniprot id: V9VUS9
names: Function
names: Subunit
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

999552:METH RS20330
gene id: 999552:METH_RS20330
uniprot id: V9W2E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

999552:METH RS14770
gene id: 999552:METH_RS14770
uniprot id: V9VW35
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS10380
gene id: 999552:METH_RS10380
uniprot id: V9VSW4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

999552:METH RS00470
gene id: 999552:METH_RS00470
uniprot id: V9VMZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

999552:METH RS11275
gene id: 999552:METH_RS11275
uniprot id: V9VVB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Could be part of an ABC transporter complex.
messages: Membrane

999552:METH RS17565
gene id: 999552:METH_RS17565
uniprot id: V9VW89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

999552:METH RS11995
gene id: 999552:METH_RS11995
uniprot id: V9VUN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

999552:METH RS04090
gene id: 999552:METH_RS04090
uniprot id: V9VN26
names: Similarity
messages: Belongs to the CobH/CbiC family.

999552:METH RS01395
gene id: 999552:METH_RS01395
uniprot id: V9VRQ9
names: Caution
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS06255
gene id: 999552:METH_RS06255
uniprot id: V9VP17
names: Similarity
messages: Belongs to the glutamine synthetase family.

999552:METH RS06125
gene id: 999552:METH_RS06125
uniprot id: V9VQW3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS01590
gene id: 999552:METH_RS01590
uniprot id: V9VPE3
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

999552:METH RS17325
gene id: 999552:METH_RS17325
uniprot id: V9VU76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

999552:METH RS04285
gene id: 999552:METH_RS04285
uniprot id: V9VN56
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

999552:METH RS20720
gene id: 999552:METH_RS20720
uniprot id: V9W091
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

999552:METH RS00475
gene id: 999552:METH_RS00475
uniprot id: V9VNV1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

999552:METH RS05485
gene id: 999552:METH_RS05485
uniprot id: V9VRI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

999552:METH RS01745
gene id: 999552:METH_RS01745
uniprot id: V9VQJ4
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS17085
gene id: 999552:METH_RS17085
uniprot id: V9VZF1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

999552:METH RS16180
gene id: 999552:METH_RS16180
uniprot id: V9VYZ8
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

999552:METH RS12540
gene id: 999552:METH_RS12540
uniprot id: V9VTZ7
names: Similarity
messages: Belongs to the GcvT family.

999552:METH RS09685
gene id: 999552:METH_RS09685
uniprot id: V9VSI6
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

999552:METH RS15545
gene id: 999552:METH_RS15545
uniprot id: V9VXC4
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

999552:METH RS13875
gene id: 999552:METH_RS13875
uniprot id: V9VWK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

999552:METH RS10485
gene id: 999552:METH_RS10485
uniprot id: V9VSY6
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

999552:METH RS07375
gene id: 999552:METH_RS07375
uniprot id: V9VSB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

999552:METH RS08995
gene id: 999552:METH_RS08995
uniprot id: V9VT58
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

999552:METH RS19730
gene id: 999552:METH_RS19730
uniprot id: V9W0Q0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS22425
gene id: 999552:METH_RS22425
uniprot id: V9W1I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MerT family.
messages: Cell inner membrane
messages: Membrane

999552:METH RS04620
gene id: 999552:METH_RS04620
uniprot id: V9VQ26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

999552:METH RS13890
gene id: 999552:METH_RS13890
uniprot id: V9VUQ6
names: Similarity
messages: Belongs to the UPF0229 family.

999552:METH RS21735
gene id: 999552:METH_RS21735
uniprot id: V9W0I3
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

999552:METH RS07170
gene id: 999552:METH_RS07170
uniprot id: V9VS86
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

999552:METH RS09830
gene id: 999552:METH_RS09830
uniprot id: V9VTJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

999552:METH RS19470
gene id: 999552:METH_RS19470
uniprot id: V9VY62
names: Similarity
messages: Belongs to the Gfa family.

999552:METH RS03375
gene id: 999552:METH_RS03375
uniprot id: V9VQE9
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

999552:METH RS05345
gene id: 999552:METH_RS05345
uniprot id: V9VRG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

999552:METH RS19930
gene id: 999552:METH_RS19930
uniprot id: V9W0U0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

999552:METH RS04545
gene id: 999552:METH_RS04545
uniprot id: V9VN92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

999552:METH RS14775
gene id: 999552:METH_RS14775
uniprot id: V9VX05
names: Subcellular Location Annotation
messages: Cell inner membrane

999552:METH RS05495
gene id: 999552:METH_RS05495
uniprot id: V9VNQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

999552:METH RS08610
gene id: 999552:METH_RS08610
uniprot id: V9VS28
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

999552:METH RS01020
gene id: 999552:METH_RS01020
uniprot id: V9VLN8
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

999552:METH RS03440
gene id: 999552:METH_RS03440
uniprot id: V9VST0
names: Similarity
messages: Belongs to the glutamine synthetase family.

999552:METH RS05470
gene id: 999552:METH_RS05470
uniprot id: V9VY88
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS16735
gene id: 999552:METH_RS16735
uniprot id: V9VW65
names: Similarity
messages: Belongs to the proline racemase family.

999552:METH RS09500
gene id: 999552:METH_RS09500
uniprot id: V9VVP4
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

999552:METH RS11540
gene id: 999552:METH_RS11540
uniprot id: V9VVF1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

999552:METH RS01695
gene id: 999552:METH_RS01695
uniprot id: V9VQI4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

999552:METH RS10180
gene id: 999552:METH_RS10180
uniprot id: V9VUT4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

999552:METH RS07530
gene id: 999552:METH_RS07530
uniprot id: V9VPI4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

999552:METH RS11760
gene id: 999552:METH_RS11760
uniprot id: V9VTN3
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS02115
gene id: 999552:METH_RS02115
uniprot id: V9VPP4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

999552:METH RS06935
gene id: 999552:METH_RS06935
uniprot id: V9VR58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane

999552:METH RS08195
gene id: 999552:METH_RS08195
uniprot id: V9VSQ4
names: Similarity
messages: Belongs to the universal stress protein A family.

999552:METH RS02180
gene id: 999552:METH_RS02180
uniprot id: V9VQU0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

999552:METH RS07485
gene id: 999552:METH_RS07485
uniprot id: V9VTF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

999552:METH RS02125
gene id: 999552:METH_RS02125
uniprot id: V9VM78
names: Similarity
messages: Belongs to the thioester dehydratase family. FabA subfamily.

999552:METH RS11965
gene id: 999552:METH_RS11965
uniprot id: V9VTR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

999552:METH RS08140
gene id: 999552:METH_RS08140
uniprot id: V9VPU4
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS11065
gene id: 999552:METH_RS11065
uniprot id: V9VV58
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

999552:METH RS16590
gene id: 999552:METH_RS16590
uniprot id: V9VZ49
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS08540
gene id: 999552:METH_RS08540
uniprot id: V9VU13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

999552:METH RS03305
gene id: 999552:METH_RS03305
uniprot id: V9VRE5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

999552:METH RS01055
gene id: 999552:METH_RS01055
uniprot id: V9VRJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

999552:METH RS17810
gene id: 999552:METH_RS17810
uniprot id: V9VZP8
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS15580
gene id: 999552:METH_RS15580
uniprot id: V9VWF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

999552:METH RS11525
gene id: 999552:METH_RS11525
uniprot id: V9VWR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

999552:METH RS07360
gene id: 999552:METH_RS07360
uniprot id: V9VPF7
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

999552:METH RS19365
gene id: 999552:METH_RS19365
uniprot id: V9VV49
names: Similarity
messages: Belongs to the SCO1/2 family.

999552:METH RS00085
gene id: 999552:METH_RS00085
uniprot id: V9VMV2
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

999552:METH RS18465
gene id: 999552:METH_RS18465
uniprot id: V9VYP2
names: Function
names: Similarity
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: May be required for disulfide bond formation in some proteins.

999552:METH RS09655
gene id: 999552:METH_RS09655
uniprot id: V9VQH1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

999552:METH RS22740
gene id: 999552:METH_RS22740
uniprot id: V9VWM7
names: Similarity
messages: Belongs to the peptidase M10B family.

999552:METH RS11600
gene id: 999552:METH_RS11600
uniprot id: V9VRF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

999552:METH RS08160
gene id: 999552:METH_RS08160
uniprot id: V9VSP8
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

999552:METH RS03230
gene id: 999552:METH_RS03230
uniprot id: V9VSP7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.

999552:METH RS18455
gene id: 999552:METH_RS18455
uniprot id: V9VX11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

999552:METH RS14910
gene id: 999552:METH_RS14910
uniprot id: V9VX23
names: Similarity
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.

999552:METH RS01075
gene id: 999552:METH_RS01075
uniprot id: V9VQ78
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

999552:METH RS15835
gene id: 999552:METH_RS15835
uniprot id: V9VTJ9
names: Cofactor
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.

999552:METH RS05260
gene id: 999552:METH_RS05260
uniprot id: V9VTR4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

999552:METH RS19415
gene id: 999552:METH_RS19415
uniprot id: V9VZ66
names: Similarity
messages: Belongs to the YciI family.

999552:METH RS09565
gene id: 999552:METH_RS09565
uniprot id: V9VSG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

999552:METH RS11145
gene id: 999552:METH_RS11145
uniprot id: V9VV75
names: Similarity
messages: Belongs to the cytochrome P450 family.

999552:METH RS09765
gene id: 999552:METH_RS09765
uniprot id: V9VUL5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS18100
gene id: 999552:METH_RS18100
uniprot id: V9VZU6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

999552:METH RS12970
gene id: 999552:METH_RS12970
uniprot id: V9VU69
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

999552:METH RS13365
gene id: 999552:METH_RS13365
uniprot id: V9VWB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

999552:METH RS07160
gene id: 999552:METH_RS07160
uniprot id: V9VUK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

999552:METH RS14470
gene id: 999552:METH_RS14470
uniprot id: V9VV84
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

999552:METH RS03265
gene id: 999552:METH_RS03265
uniprot id: V9VPG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

999552:METH RS09400
gene id: 999552:METH_RS09400
uniprot id: V9VSD8
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

999552:METH RS06805
gene id: 999552:METH_RS06805
uniprot id: V9VR35
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

999552:METH RS15370
gene id: 999552:METH_RS15370
uniprot id: V9VWC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

999552:METH RS00025
gene id: 999552:METH_RS00025
uniprot id: V9VL87
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

999552:METH RS17850
gene id: 999552:METH_RS17850
uniprot id: V9VYD8
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS10205
gene id: 999552:METH_RS10205
uniprot id: V9VUT8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

999552:METH RS16290
gene id: 999552:METH_RS16290
uniprot id: V9VW00
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

999552:METH RS13455
gene id: 999552:METH_RS13455
uniprot id: V9VSE0
names: Function
names: Similarity
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.

999552:METH RS19845
gene id: 999552:METH_RS19845
uniprot id: V9VYE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

999552:METH RS20830
gene id: 999552:METH_RS20830
uniprot id: V9VXJ6
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

999552:METH RS02815
gene id: 999552:METH_RS02815
uniprot id: V9VMM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

999552:METH RS05835
gene id: 999552:METH_RS05835
uniprot id: V9VRP1
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

999552:METH RS07385
gene id: 999552:METH_RS07385
uniprot id: V9VPG3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

999552:METH RS22620
gene id: 999552:METH_RS22620
uniprot id: V9W023
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

999552:METH RS19570
gene id: 999552:METH_RS19570
uniprot id: V9VY87
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

999552:METH RS00570
gene id: 999552:METH_RS00570
uniprot id: V9VNX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

999552:METH RS07580
gene id: 999552:METH_RS07580
uniprot id: V9VPJ4
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

999552:METH RS11825
gene id: 999552:METH_RS11825
uniprot id: V9VVI4
names: Similarity
messages: Belongs to the peptidase M1 family.

999552:METH RS06035
gene id: 999552:METH_RS06035
uniprot id: V9VST6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

999552:METH RS21555
gene id: 999552:METH_RS21555
uniprot id: V9W0T6
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

999552:METH RS07225
gene id: 999552:METH_RS07225
uniprot id: V9VTB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

999552:METH RS03800
gene id: 999552:METH_RS03800
uniprot id: V9VSY2
names: Similarity
messages: Belongs to the GcvT family.

999552:METH RS01910
gene id: 999552:METH_RS01910
uniprot id: V9VRZ8
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.

999552:METH RS02835
gene id: 999552:METH_RS02835
uniprot id: V9VQ52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the carboxylate-amine ligase family. Glutamate--cysteine ligase type 2 subfamily.
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).
messages: Homodimer or monomer when oxidized or reduced, respectively.
messages: chloroplast

999552:METH RS06800
gene id: 999552:METH_RS06800
uniprot id: V9VUD4
names: Similarity
messages: Belongs to the Gfa family.

999552:METH RS09415
gene id: 999552:METH_RS09415
uniprot id: V9VQD3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

999552:METH RS15435
gene id: 999552:METH_RS15435
uniprot id: V9VTD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

999552:METH RS14350
gene id: 999552:METH_RS14350
uniprot id: V9VWU7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

999552:METH RS19045
gene id: 999552:METH_RS19045
uniprot id: V9VYZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

999552:METH RS19935
gene id: 999552:METH_RS19935
uniprot id: V9VXW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

999552:METH RS06055
gene id: 999552:METH_RS06055
uniprot id: V9VQV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

999552:METH RS02660
gene id: 999552:METH_RS02660
uniprot id: V9VMJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

999552:METH RS00045
gene id: 999552:METH_RS00045
uniprot id: V9VPR6
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

999552:METH RS18885
gene id: 999552:METH_RS18885
uniprot id: V9VYW3
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS18150
gene id: 999552:METH_RS18150
uniprot id: V9VZV7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

999552:METH RS18190
gene id: 999552:METH_RS18190
uniprot id: V9VYJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

999552:METH RS04375
gene id: 999552:METH_RS04375
uniprot id: V9VPX9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS19250
gene id: 999552:METH_RS19250
uniprot id: V9VXG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

999552:METH RS17445
gene id: 999552:METH_RS17445
uniprot id: V9VY72
names: Similarity
messages: Belongs to the UPF0262 family.

999552:METH RS05755
gene id: 999552:METH_RS05755
uniprot id: V9VSP9
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS01220
gene id: 999552:METH_RS01220
uniprot id: V9VP87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

999552:METH RS17910
gene id: 999552:METH_RS17910
uniprot id: V9VUH4
names: Similarity
messages: Belongs to the peptidase S41A family.

999552:METH RS11480
gene id: 999552:METH_RS11480
uniprot id: V9VTI1
names: Similarity
messages: Belongs to the DEAD box helicase family.

999552:METH RS02710
gene id: 999552:METH_RS02710
uniprot id: V9VMK2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

999552:METH RS18935
gene id: 999552:METH_RS18935
uniprot id: V9VYX3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

999552:METH RS16185
gene id: 999552:METH_RS16185
uniprot id: V9W0Q2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

999552:METH RS04975
gene id: 999552:METH_RS04975
uniprot id: V9VTJ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

999552:METH RS03055
gene id: 999552:METH_RS03055
uniprot id: V9VPD2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

999552:METH RS19070
gene id: 999552:METH_RS19070
uniprot id: V9VYZ6
names: Similarity
messages: Belongs to the YkuD family.

999552:METH RS14125
gene id: 999552:METH_RS14125
uniprot id: V9VWR5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

999552:METH RS19245
gene id: 999552:METH_RS19245
uniprot id: V9W0F3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

999552:METH RS00060
gene id: 999552:METH_RS00060
uniprot id: V9VMV0
names: Similarity
messages: Belongs to the peptidase M16 family.

999552:METH RS06225
gene id: 999552:METH_RS06225
uniprot id: V9VU72
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

999552:METH RS17925
gene id: 999552:METH_RS17925
uniprot id: V9VXF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

999552:METH RS07540
gene id: 999552:METH_RS07540
uniprot id: V9VRF8
names: Similarity
messages: Belongs to the LOG family.

999552:METH RS17005
gene id: 999552:METH_RS17005
uniprot id: V9VU10
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

999552:METH RS13100
gene id: 999552:METH_RS13100
uniprot id: V9VU92
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Interacts with CtaA.
messages: Membrane

999552:METH RS00535
gene id: 999552:METH_RS00535
uniprot id: V9VRA7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS13190
gene id: 999552:METH_RS13190
uniprot id: V9VW79
names: Similarity
messages: Belongs to the GSP E family.

999552:METH RS10565
gene id: 999552:METH_RS10565
uniprot id: V9VQX5
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

999552:METH RS00020
gene id: 999552:METH_RS00020
uniprot id: V9VPR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

999552:METH RS02535
gene id: 999552:METH_RS02535
uniprot id: V9VQ02
names: Similarity
messages: Belongs to the Nudix hydrolase family.

999552:METH RS01120
gene id: 999552:METH_RS01120
uniprot id: V9VP68
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

999552:METH RS20530
gene id: 999552:METH_RS20530
uniprot id: V9VZN6
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS02160
gene id: 999552:METH_RS02160
uniprot id: V9VS48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

999552:METH RS01365
gene id: 999552:METH_RS01365
uniprot id: V9VRQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

999552:METH RS04145
gene id: 999552:METH_RS04145
uniprot id: V9VT38
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

999552:METH RS08720
gene id: 999552:METH_RS08720
uniprot id: V9VS43
names: Similarity
messages: Belongs to the YkuD family.

999552:METH RS05830
gene id: 999552:METH_RS05830
uniprot id: V9VQR9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS03445
gene id: 999552:METH_RS03445
uniprot id: V9VPJ1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

999552:METH RS08765
gene id: 999552:METH_RS08765
uniprot id: V9VU44
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS21090
gene id: 999552:METH_RS21090
uniprot id: V9W2W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

999552:METH RS08020
gene id: 999552:METH_RS08020
uniprot id: V9VRR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

999552:METH RS00595
gene id: 999552:METH_RS00595
uniprot id: V9VNX4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

999552:METH RS01295
gene id: 999552:METH_RS01295
uniprot id: V9VPA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

999552:METH RS13300
gene id: 999552:METH_RS13300
uniprot id: V9VXN8
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

999552:METH RS08510
gene id: 999552:METH_RS08510
uniprot id: V9VSX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

999552:METH RS16390
gene id: 999552:METH_RS16390
uniprot id: V9VTS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

999552:METH RS16085
gene id: 999552:METH_RS16085
uniprot id: V9VVX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

999552:METH RS15350
gene id: 999552:METH_RS15350
uniprot id: V9VTC3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

999552:METH RS13405
gene id: 999552:METH_RS13405
uniprot id: V9VSD2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

999552:METH RS13880
gene id: 999552:METH_RS13880
uniprot id: V9VSL5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

999552:METH RS08865
gene id: 999552:METH_RS08865
uniprot id: V9VS63
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

999552:METH RS19705
gene id: 999552:METH_RS19705
uniprot id: V9VXQ1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

999552:METH RS06210
gene id: 999552:METH_RS06210
uniprot id: V9VSW2
names: Subcellular Location Annotation
messages: Cytoplasm

999552:METH RS20990
gene id: 999552:METH_RS20990
uniprot id: V9W0G2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

999552:METH RS05275
gene id: 999552:METH_RS05275
uniprot id: V9VSG0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

999552:METH RS01445
gene id: 999552:METH_RS01445
uniprot id: V9VLW2
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

999552:METH RS01690
gene id: 999552:METH_RS01690
uniprot id: V9VPG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

999552:METH RS02445
gene id: 999552:METH_RS02445
uniprot id: V9VMD0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

999552:METH RS09820
gene id: 999552:METH_RS09820
uniprot id: V9VQK2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

999552:METH RS20175
gene id: 999552:METH_RS20175
uniprot id: V9VY01
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

999552:METH RS11505
gene id: 999552:METH_RS11505
uniprot id: V9VTI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

999552:METH RS08770
gene id: 999552:METH_RS08770
uniprot id: V9VQ33
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

999552:METH RS05450
gene id: 999552:METH_RS05450
uniprot id: V9VRH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

999552:METH RS11665
gene id: 999552:METH_RS11665
uniprot id: V9VUH3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

999552:METH RS07565
gene id: 999552:METH_RS07565
uniprot id: V9VRG3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

999552:METH RS09835
gene id: 999552:METH_RS09835
uniprot id: V9VUN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.
messages: Membrane

999552:METH RS01345
gene id: 999552:METH_RS01345
uniprot id: V9VNF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

999552:METH RS12025
gene id: 999552:METH_RS12025
uniprot id: V9VVL9
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

999552:METH RS08605
gene id: 999552:METH_RS08605
uniprot id: V9VV88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

999552:METH RS19875
gene id: 999552:METH_RS19875
uniprot id: V9VYF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

999552:METH RS06375
gene id: 999552:METH_RS06375
uniprot id: V9VSZ1
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS13495
gene id: 999552:METH_RS13495
uniprot id: V9VVD9
names: Similarity
messages: Belongs to the bacterial glucokinase family.

999552:METH RS00530
gene id: 999552:METH_RS00530
uniprot id: V9VLF3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

999552:METH RS10905
gene id: 999552:METH_RS10905
uniprot id: V9VR20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

999552:METH RS02715
gene id: 999552:METH_RS02715
uniprot id: V9VSG9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS05400
gene id: 999552:METH_RS05400
uniprot id: V9VRH1
names: Similarity
messages: Belongs to the GARS family.

999552:METH RS11820
gene id: 999552:METH_RS11820
uniprot id: V9VUK2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

999552:METH RS05820
gene id: 999552:METH_RS05820
uniprot id: V9VNV7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Binds 2 potassium ions per subunit.
messages: Dimer of dimers.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS19025
gene id: 999552:METH_RS19025
uniprot id: V9VUZ6
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

999552:METH RS13695
gene id: 999552:METH_RS13695
uniprot id: V9VXV5
names: Subcellular Location Annotation
messages: Cytoplasm

999552:METH RS13280
gene id: 999552:METH_RS13280
uniprot id: V9VUC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

999552:METH RS16880
gene id: 999552:METH_RS16880
uniprot id: V9VZA1
names: Similarity
messages: Belongs to the GroES chaperonin family.

999552:METH RS19680
gene id: 999552:METH_RS19680
uniprot id: V9VYA9
names: Subcellular Location Annotation
messages: Cell inner membrane

999552:METH RS07390
gene id: 999552:METH_RS07390
uniprot id: V9VUP3
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS01195
gene id: 999552:METH_RS01195
uniprot id: V9VP81
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

999552:METH RS01990
gene id: 999552:METH_RS01990
uniprot id: V9VQP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

999552:METH RS01145
gene id: 999552:METH_RS01145
uniprot id: V9VP74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

999552:METH RS06245
gene id: 999552:METH_RS06245
uniprot id: V9VRV5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

999552:METH RS19240
gene id: 999552:METH_RS19240
uniprot id: V9VV26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

999552:METH RS19500
gene id: 999552:METH_RS19500
uniprot id: V9VZ81
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

999552:METH RS10185
gene id: 999552:METH_RS10185
uniprot id: V9VQR2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

999552:METH RS11400
gene id: 999552:METH_RS11400
uniprot id: V9VVD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

999552:METH RS20145
gene id: 999552:METH_RS20145
uniprot id: V9W0W6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS17735
gene id: 999552:METH_RS17735
uniprot id: V9VZN8
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

999552:METH RS10980
gene id: 999552:METH_RS10980
uniprot id: V9VU27
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

999552:METH RS02480
gene id: 999552:METH_RS02480
uniprot id: V9VP12
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS02980
gene id: 999552:METH_RS02980
uniprot id: V9VSK9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

999552:METH RS22110
gene id: 999552:METH_RS22110
uniprot id: V9W275
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS20565
gene id: 999552:METH_RS20565
uniprot id: V9W2K9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

999552:METH RS06170
gene id: 999552:METH_RS06170
uniprot id: V9VU65
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS20460
gene id: 999552:METH_RS20460
uniprot id: V9VZM2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

999552:METH RS04420
gene id: 999552:METH_RS04420
uniprot id: V9VN76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

999552:METH RS11880
gene id: 999552:METH_RS11880
uniprot id: V9VRL5
names: Similarity
messages: Belongs to the peptidase M24B family.

999552:METH RS19710
gene id: 999552:METH_RS19710
uniprot id: V9VYB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Cell membrane
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

999552:METH RS12065
gene id: 999552:METH_RS12065
uniprot id: V9VUP7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

999552:METH RS08835
gene id: 999552:METH_RS08835
uniprot id: V9VVC6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

999552:METH RS06900
gene id: 999552:METH_RS06900
uniprot id: V9VP83
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

999552:METH RS18275
gene id: 999552:METH_RS18275
uniprot id: V9VZY1
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

999552:METH RS05465
gene id: 999552:METH_RS05465
uniprot id: V9VTW4
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

999552:METH RS11250
gene id: 999552:METH_RS11250
uniprot id: V9VRB0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

999552:METH RS16020
gene id: 999552:METH_RS16020
uniprot id: V9VXJ5
names: Similarity
messages: Belongs to the IucA/IucC family.

999552:METH RS14520
gene id: 999552:METH_RS14520
uniprot id: V9VV91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

999552:METH RS07680
gene id: 999552:METH_RS07680
uniprot id: V9VSG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

999552:METH RS05270
gene id: 999552:METH_RS05270
uniprot id: V9VRC7
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS01100
gene id: 999552:METH_RS01100
uniprot id: V9VQ81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

999552:METH RS02280
gene id: 999552:METH_RS02280
uniprot id: V9VMA0
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

999552:METH RS09615
gene id: 999552:METH_RS09615
uniprot id: V9VSH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

999552:METH RS04560
gene id: 999552:METH_RS04560
uniprot id: V9VQY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

999552:METH RS02465
gene id: 999552:METH_RS02465
uniprot id: V9VQY7
names: Similarity
messages: Belongs to the RNase T2 family.

999552:METH RS02015
gene id: 999552:METH_RS02015
uniprot id: V9VQQ0
names: Subcellular Location Annotation
messages: Cell inner membrane

999552:METH RS22140
gene id: 999552:METH_RS22140
uniprot id: V9VYJ8
names: Similarity
messages: Belongs to the DSD1 family.

999552:METH RS17945
gene id: 999552:METH_RS17945
uniprot id: V9VUH8
names: Similarity
messages: Belongs to the GcvT family.

999552:METH RS10510
gene id: 999552:METH_RS10510
uniprot id: V9VW90
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

999552:METH RS03015
gene id: 999552:METH_RS03015
uniprot id: V9VQ84
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

999552:METH RS00560
gene id: 999552:METH_RS00560
uniprot id: V9VRB2
names: Function
names: Similarity
messages: A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex.
messages: Belongs to the bacterial AtpI family.

999552:METH RS16055
gene id: 999552:METH_RS16055
uniprot id: V9VYX5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily.

999552:METH RS09745
gene id: 999552:METH_RS09745
uniprot id: V9VQI6
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS03585
gene id: 999552:METH_RS03585
uniprot id: V9VRJ8
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.

999552:METH RS01905
gene id: 999552:METH_RS01905
uniprot id: V9VM36
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

999552:METH RS09490
gene id: 999552:METH_RS09490
uniprot id: V9VUG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

999552:METH RS18900
gene id: 999552:METH_RS18900
uniprot id: V9VX94
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

999552:METH RS07735
gene id: 999552:METH_RS07735
uniprot id: V9VUU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.
messages: Oligomer of 12 subunits arranged in the form of two hexameric ring.

999552:METH RS19265
gene id: 999552:METH_RS19265
uniprot id: V9VV32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

999552:METH RS02490
gene id: 999552:METH_RS02490
uniprot id: V9VQZ2
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

999552:METH RS01765
gene id: 999552:METH_RS01765
uniprot id: V9VPH8
names: Similarity
messages: Belongs to the YkuD family.

999552:METH RS21430
gene id: 999552:METH_RS21430
uniprot id: V9VXX3
names: Similarity
messages: Belongs to the Gfa family.

999552:METH RS01005
gene id: 999552:METH_RS01005
uniprot id: V9VN85
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

999552:METH RS04315
gene id: 999552:METH_RS04315
uniprot id: V9VN61
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

999552:METH RS14110
gene id: 999552:METH_RS14110
uniprot id: V9VY21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

999552:METH RS00720
gene id: 999552:METH_RS00720
uniprot id: V9VQ14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

999552:METH RS03740
gene id: 999552:METH_RS03740
uniprot id: V9VPM7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS07955
gene id: 999552:METH_RS07955
uniprot id: V9VTP3
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS08985
gene id: 999552:METH_RS08985
uniprot id: V9VVG6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

999552:METH RS14260
gene id: 999552:METH_RS14260
uniprot id: V9VY34
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

999552:METH RS17860
gene id: 999552:METH_RS17860
uniprot id: V9VZQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

999552:METH RS00680
gene id: 999552:METH_RS00680
uniprot id: V9VN29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

999552:METH RS12810
gene id: 999552:METH_RS12810
uniprot id: V9VV05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

999552:METH RS17670
gene id: 999552:METH_RS17670
uniprot id: V9VXA8
names: Similarity
messages: Belongs to the FMO family.

999552:METH RS08785
gene id: 999552:METH_RS08785
uniprot id: V9VS52
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS17250
gene id: 999552:METH_RS17250
uniprot id: V9VZG4
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

999552:METH RS18345
gene id: 999552:METH_RS18345
uniprot id: V9VUP9
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

999552:METH RS14240
gene id: 999552:METH_RS14240
uniprot id: V9VVU8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

999552:METH RS04570
gene id: 999552:METH_RS04570
uniprot id: V9VN96
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

999552:METH RS05595
gene id: 999552:METH_RS05595
uniprot id: V9VRK0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

999552:METH RS15965
gene id: 999552:METH_RS15965
uniprot id: V9VWJ5
names: Similarity
messages: Belongs to the CFA/CMAS family.

999552:METH RS19780
gene id: 999552:METH_RS19780
uniprot id: V9VVD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

999552:METH RS21740
gene id: 999552:METH_RS21740
uniprot id: V9W0Y1
names: Similarity
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.

999552:METH RS14215
gene id: 999552:METH_RS14215
uniprot id: V9VWS5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

999552:METH RS13620
gene id: 999552:METH_RS13620
uniprot id: V9VXU6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

999552:METH RS03330
gene id: 999552:METH_RS03330
uniprot id: V9VRE9
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS14450
gene id: 999552:METH_RS14450
uniprot id: V9VVY7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS13105
gene id: 999552:METH_RS13105
uniprot id: V9VV51
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

999552:METH RS12665
gene id: 999552:METH_RS12665
uniprot id: V9VRZ0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS18295
gene id: 999552:METH_RS18295
uniprot id: V9VUP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

999552:METH RS20740
gene id: 999552:METH_RS20740
uniprot id: V9VZT1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

999552:METH RS08455
gene id: 999552:METH_RS08455
uniprot id: V9VTZ8
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

999552:METH RS04885
gene id: 999552:METH_RS04885
uniprot id: V9VR40
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS02110
gene id: 999552:METH_RS02110
uniprot id: V9VNT4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

999552:METH RS14900
gene id: 999552:METH_RS14900
uniprot id: V9VVD5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

999552:METH RS16630
gene id: 999552:METH_RS16630
uniprot id: V9VWS4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS03895
gene id: 999552:METH_RS03895
uniprot id: V9VQM4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

999552:METH RS00110
gene id: 999552:METH_RS00110
uniprot id: V9VR50
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

999552:METH RS03500
gene id: 999552:METH_RS03500
uniprot id: V9VQH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

999552:METH RS14880
gene id: 999552:METH_RS14880
uniprot id: V9VW52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

999552:METH RS07985
gene id: 999552:METH_RS07985
uniprot id: V9VPR4
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

999552:METH RS02990
gene id: 999552:METH_RS02990
uniprot id: V9VQ79
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

999552:METH RS05100
gene id: 999552:METH_RS05100
uniprot id: V9VTM4
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

999552:METH RS00185
gene id: 999552:METH_RS00185
uniprot id: V9VPU0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

999552:METH RS07310
gene id: 999552:METH_RS07310
uniprot id: V9VUM9
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

999552:METH RS09780
gene id: 999552:METH_RS09780
uniprot id: V9VSK6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

999552:METH RS00050
gene id: 999552:METH_RS00050
uniprot id: V9VL90
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

999552:METH RS08685
gene id: 999552:METH_RS08685
uniprot id: V9VQ21
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

999552:METH RS00800
gene id: 999552:METH_RS00800
uniprot id: V9VN48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

999552:METH RS03060
gene id: 999552:METH_RS03060
uniprot id: V9VQ92
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

999552:METH RS05545
gene id: 999552:METH_RS05545
uniprot id: V9VRJ2
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS05280
gene id: 999552:METH_RS05280
uniprot id: V9VNK3
names: Similarity
messages: Belongs to the nitrile hydratase subunit alpha family.

999552:METH RS03545
gene id: 999552:METH_RS03545
uniprot id: V9VPK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

999552:METH RS08825
gene id: 999552:METH_RS08825
uniprot id: V9VU54
names: Subcellular Location Annotation
messages: Secreted

999552:METH RS04105
gene id: 999552:METH_RS04105
uniprot id: V9VQQ5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

999552:METH RS14515
gene id: 999552:METH_RS14515
uniprot id: V9VY78
names: Subunit
messages: Homotrimer.

999552:METH RS14375
gene id: 999552:METH_RS14375
uniprot id: V9VVX5
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

999552:METH RS18915
gene id: 999552:METH_RS18915
uniprot id: V9VUY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

999552:METH RS07905
gene id: 999552:METH_RS07905
uniprot id: V9VPP8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

999552:METH RS02325
gene id: 999552:METH_RS02325
uniprot id: V9VPT4
names: Similarity
messages: Belongs to the pyruvate kinase family.

999552:METH RS20250
gene id: 999552:METH_RS20250
uniprot id: V9W110
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

999552:METH RS02425
gene id: 999552:METH_RS02425
uniprot id: V9VP00
names: Similarity
messages: Belongs to the AlaDH/PNT family.

999552:METH RS11655
gene id: 999552:METH_RS11655
uniprot id: V9VWT6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

999552:METH RS06825
gene id: 999552:METH_RS06825
uniprot id: V9VP69
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

999552:METH RS07970
gene id: 999552:METH_RS07970
uniprot id: V9VRQ0
names: Similarity
messages: Belongs to the leucine-binding protein family.

999552:METH RS19080
gene id: 999552:METH_RS19080
uniprot id: V9W0B6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

999552:METH RS01095
gene id: 999552:METH_RS01095
uniprot id: V9VP64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

999552:METH RS13450
gene id: 999552:METH_RS13450
uniprot id: V9VWD2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

999552:METH RS19905
gene id: 999552:METH_RS19905
uniprot id: V9W0T8
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

999552:METH RS01160
gene id: 999552:METH_RS01160
uniprot id: V9VRL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

999552:METH RS15685
gene id: 999552:METH_RS15685
uniprot id: V9VVQ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

999552:METH RS12595
gene id: 999552:METH_RS12595
uniprot id: V9VUX3
names: Similarity
messages: Belongs to the pirin family.

999552:METH RS16705
gene id: 999552:METH_RS16705
uniprot id: V9VZ74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

999552:METH RS18480
gene id: 999552:METH_RS18480
uniprot id: V9VX15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

999552:METH RS09805
gene id: 999552:METH_RS09805
uniprot id: V9VSL2
names: Similarity
messages: Belongs to the virb1 family.

999552:METH RS13485
gene id: 999552:METH_RS13485
uniprot id: V9VXS4
names: Subcellular Location Annotation
messages: Cell outer membrane

999552:METH RS09505
gene id: 999552:METH_RS09505
uniprot id: V9VSF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

999552:METH RS12815
gene id: 999552:METH_RS12815
uniprot id: V9VVZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

999552:METH RS04950
gene id: 999552:METH_RS04950
uniprot id: V9VTJ1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

999552:METH RS19600
gene id: 999552:METH_RS19600
uniprot id: V9VZA0
names: Similarity
messages: Belongs to the histone deacetylase family.

999552:METH RS08855
gene id: 999552:METH_RS08855
uniprot id: V9VQ45
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

999552:METH RS20635
gene id: 999552:METH_RS20635
uniprot id: V9VXF6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

999552:METH RS21065
gene id: 999552:METH_RS21065
uniprot id: V9W1F8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

999552:METH RS14720
gene id: 999552:METH_RS14720
uniprot id: V9VT22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

999552:METH RS14270
gene id: 999552:METH_RS14270
uniprot id: V9VVV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

999552:METH RS15765
gene id: 999552:METH_RS15765
uniprot id: V9VYR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

999552:METH RS05070
gene id: 999552:METH_RS05070
uniprot id: V9VNF8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

999552:METH RS04290
gene id: 999552:METH_RS04290
uniprot id: V9VT66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

999552:METH RS01010
gene id: 999552:METH_RS01010
uniprot id: V9VP50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

999552:METH RS09785
gene id: 999552:METH_RS09785
uniprot id: V9VTI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

999552:METH RS00460
gene id: 999552:METH_RS00460
uniprot id: V9VLE1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

999552:METH RS20750
gene id: 999552:METH_RS20750
uniprot id: V9W195
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

999552:METH RS04635
gene id: 999552:METH_RS04635
uniprot id: V9VNA3
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

999552:METH RS14410
gene id: 999552:METH_RS14410
uniprot id: V9VSX0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

999552:METH RS15425
gene id: 999552:METH_RS15425
uniprot id: V9VWD5
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

999552:METH RS07325
gene id: 999552:METH_RS07325
uniprot id: V9VTD0
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

999552:METH RS21565
gene id: 999552:METH_RS21565
uniprot id: V9VY03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

999552:METH RS03170
gene id: 999552:METH_RS03170
uniprot id: V9VRC4
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

999552:METH RS15905
gene id: 999552:METH_RS15905
uniprot id: V9VYU0
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS06925
gene id: 999552:METH_RS06925
uniprot id: V9VP86
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Multidrug efflux pump.

999552:METH RS14825
gene id: 999552:METH_RS14825
uniprot id: V9VX13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

999552:METH RS15535
gene id: 999552:METH_RS15535
uniprot id: V9VVM8
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

999552:METH RS02890
gene id: 999552:METH_RS02890
uniprot id: V9VQ62
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

999552:METH RS00400
gene id: 999552:METH_RS00400
uniprot id: V9VPW4
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

999552:METH RS20525
gene id: 999552:METH_RS20525
uniprot id: V9W2J8
names: Subcellular Location Annotation
messages: Membrane

999552:METH RS13795
gene id: 999552:METH_RS13795
uniprot id: V9VSJ8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.