9755:GLYCTK
gene id: 9755:GLYCTK
uniprot id: A0A2Y9EPR5
names: Similarity
messages: Belongs to the glycerate kinase type-2 family.

9755:PROM1
gene id: 9755:PROM1
uniprot id: A0A2Y9SHU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prominin family.
messages: Membrane
messages: microvillus membrane

9755:LOC112067096
gene id: 9755:LOC112067096
uniprot id: A0A2Y9THM9
names: Similarity
messages: Belongs to the COX20 family.

9755:MIF
gene id: 9755:MIF
uniprot id: A0A2Y9SH80
names: Similarity
messages: Belongs to the MIF family.

9755:TAC1
gene id: 9755:TAC1
uniprot id: A0A2Y9FGB3
uniprot id: A0A455B8I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted
messages: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.

9755:SLC12A5
gene id: 9755:SLC12A5
uniprot id: A0A2Y9F5E6
uniprot id: A0A2Y9F5K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

9755:ZSCAN30
gene id: 9755:ZSCAN30
uniprot id: A0A2Y9FHH3
names: Subcellular Location Annotation
messages: Nucleus

9755:LOC102976446
gene id: 9755:LOC102976446
uniprot id: A0A2Y9F192
uniprot id: A0A2Y9F1T5
uniprot id: A0A2Y9F2M5
uniprot id: A0A455BBF9
names: Similarity
messages: Belongs to the protease inhibitor I47 (latexin) family.

9755:MAPK9
gene id: 9755:MAPK9
uniprot id: A0A2Y9S3T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

9755:EGFLAM
gene id: 9755:EGFLAM
uniprot id: A0A2Y9SRB6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:ATP1B2
gene id: 9755:ATP1B2
uniprot id: A0A2Y9EF34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

9755:ATP11C
gene id: 9755:ATP11C
uniprot id: A0A2Y9EDC2
uniprot id: A0A2Y9EEE1
uniprot id: A0A2Y9EEF0
uniprot id: A0A2Y9EF30
uniprot id: A0A455AND5
uniprot id: A0A455AQ21
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:ADAMTS3
gene id: 9755:ADAMTS3
uniprot id: A0A2Y9RXD8
uniprot id: A0A2Y9S4X4
uniprot id: A0A455BIH1
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9755:ZFPM2
gene id: 9755:ZFPM2
uniprot id: A0A455C4M4
names: Subcellular Location Annotation
messages: Nucleus

9755:PTGER4
gene id: 9755:PTGER4
uniprot id: A0A2Y9F0E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with FEM1A.
messages: Membrane
messages: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.

9755:VCP
gene id: 9755:VCP
uniprot id: A0A2Y9EZQ3
names: Similarity
messages: Belongs to the AAA ATPase family.

9755:EFNB1
gene id: 9755:EFNB1
uniprot id: A0A2Y9EHF8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:IRX2
gene id: 9755:IRX2
uniprot id: A0A2Y9SSY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

9755:KEF67 p06
gene id: 9755:KEF67_p06
uniprot id: Q9MES9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I.
messages: Mitochondrion membrane

9755:LOC102980944
gene id: 9755:LOC102980944
uniprot id: A0A2Y9F5C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TTC30/dfy-1/fleer family.
messages: Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip.
messages: cilium

9755:PRKN
gene id: 9755:PRKN
uniprot id: A0A455BNM5
uniprot id: A0A455BNN0
uniprot id: A0A455BNP2
uniprot id: A0A455BPA5
uniprot id: A0A455C3Q4
uniprot id: A0A455C3Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RBR family. Parkin subfamily.
messages: Forms an E3 ubiquitin ligase complex.
messages: Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.
messages: Mitochondrion

9755:TMPRSS5
gene id: 9755:TMPRSS5
uniprot id: A0A455C9N4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:CD40
gene id: 9755:CD40
uniprot id: A0A455C2R6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:THNSL1
gene id: 9755:THNSL1
uniprot id: A0A2Y9FBC8
names: Similarity
messages: Belongs to the threonine synthase family.

9755:CUL3
gene id: 9755:CUL3
uniprot id: A0A2Y9SNR1
names: Similarity
messages: Belongs to the cullin family.

9755:CCNY
gene id: 9755:CCNY
uniprot id: A0A2Y9T971
uniprot id: A0A455BS24
names: Similarity
messages: Belongs to the cyclin family. Cyclin Y subfamily.

9755:CMAS
gene id: 9755:CMAS
uniprot id: A0A2Y9EZR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CMP-NeuNAc synthase family.
messages: Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN).
messages: Homotetramer; the active enzyme is formed by a dimer of dimers.

9755:FZD9
gene id: 9755:FZD9
uniprot id: A0A2Y9SPN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

9755:TUSC3
gene id: 9755:TUSC3
uniprot id: A0A2Y9T8D8
uniprot id: A0A2Y9TG58
uniprot id: A0A455AK73
uniprot id: A0A455AKH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:ITGA9
gene id: 9755:ITGA9
uniprot id: A0A2Y9TB19
uniprot id: A0A455ADD4
uniprot id: A0A455ADR8
uniprot id: A0A455AR20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9755:GPAT4
gene id: 9755:GPAT4
uniprot id: A0A2Y9FPG2
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

9755:LOC102981962
gene id: 9755:LOC102981962
uniprot id: A0A2Y9F6L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 6A family.
messages: Membrane
messages: Mitochondrion inner membrane

9755:LOC102975416
gene id: 9755:LOC102975416
uniprot id: A0A2Y9SVV1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

9755:AP4S1
gene id: 9755:AP4S1
uniprot id: A0A2Y9F2Y4
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

9755:SMG7
gene id: 9755:SMG7
uniprot id: A0A2Y9TFC4
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Plays a role in nonsense-mediated mRNA decay.

9755:KPNA6
gene id: 9755:KPNA6
uniprot id: A0A2Y9FJU4
uniprot id: A0A455B177
uniprot id: A0A455BFC9
names: Function
names: Similarity
messages: Belongs to the importin alpha family.
messages: Functions in nuclear protein import.

9755:HRH4
gene id: 9755:HRH4
uniprot id: A0A2Y9F727
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9755:SUSD3
gene id: 9755:SUSD3
uniprot id: A0A2Y9S310
uniprot id: A0A2Y9SAX1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:PCNP
gene id: 9755:PCNP
uniprot id: A0A2Y9EP78
uniprot id: A0A455BL97
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with UHRF2/NIRF.
messages: May be involved in cell cycle regulation.
messages: Nucleus

9755:LOC112064309
gene id: 9755:LOC112064309
uniprot id: A0A2Y9SFN3
names: Similarity
messages: Belongs to the cyclin family.

9755:LOC114483892
gene id: 9755:LOC114483892
uniprot id: A0A455C6T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway.
messages: Belongs to the NPR3 family.
messages: Lysosome

9755:OTP
gene id: 9755:OTP
uniprot id: A0A2Y9S730
names: Subcellular Location Annotation
messages: Nucleus

9755:RNF5
gene id: 9755:RNF5
uniprot id: A0A2Y9FCP3
uniprot id: A0A455AH72
names: Domain
names: Function
names: Subcellular Location Annotation
messages: E3 ubiquitin-protein ligase.
messages: Endoplasmic reticulum membrane
messages: Mitochondrion membrane
messages: The RING-type zinc finger domain is responsible for E3 ligase activity.

9755:IL18
gene id: 9755:IL18
uniprot id: A0A2Y9TBD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-1 family.
messages: Cytoplasm
messages: Forms a ternary complex with ligand-binding receptor subunit IL18R1 and signaling receptor subunit IL18RAP at the plasma membrane. Mature IL18 first binds to IL18R1 forming a low affinity binary complex, which then interacts with IL18RAP to form a high affinity ternary complex that signals inside the cell. Interacts with cargo receptor TMED10; the interaction mediates the translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) and thereby secretion.
messages: Pro-inflammatory cytokine primarily involved in epithelial barrier repair, polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
messages: Secreted

9755:LOC114484344
gene id: 9755:LOC114484344
uniprot id: A0A455AIT6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:LOC102993493
gene id: 9755:LOC102993493
uniprot id: A0A2Y9FPD7
names: Subcellular Location Annotation
messages: Membrane

9755:LOC102994592
gene id: 9755:LOC102994592
uniprot id: A0A2Y9S3N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NXF family.
messages: Cytoplasm

9755:TXNL4A
gene id: 9755:TXNL4A
uniprot id: A0A2Y9TFK5
uniprot id: A0A2Y9TKF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

9755:PROP1
gene id: 9755:PROP1
uniprot id: A0A2Y9FIK4
uniprot id: A0A2Y9S0G0
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Possibly involved in the ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes and caudomedial thyrotropes.

9755:IFNGR2
gene id: 9755:IFNGR2
uniprot id: A0A2Y9SCC1
uniprot id: A0A455BHY7
names: Subcellular Location Annotation
messages: Membrane

9755:HSF5
gene id: 9755:HSF5
uniprot id: A0A2Y9T6N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

9755:PIK3C2B
gene id: 9755:PIK3C2B
uniprot id: A0A455B5Y7
uniprot id: A0A455B5Z5
uniprot id: A0A455B6B5
uniprot id: A0A455B6C1
uniprot id: A0A455B6C8
uniprot id: A0A455B6U9
uniprot id: A0A455B6V7
uniprot id: A0A455B8N8
uniprot id: A0A455B8P3
uniprot id: A0A455B8P8
uniprot id: A0A455BKC8
uniprot id: A0A455BKD3
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

9755:RIPPLY1
gene id: 9755:RIPPLY1
uniprot id: A0A455AQ05
uniprot id: A0A455AQ85
uniprot id: A0A455AS50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ripply family.
messages: Nucleus

9755:SMG6
gene id: 9755:SMG6
uniprot id: A0A455CA58
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Plays a role in nonsense-mediated mRNA decay.

9755:ADAMTS16
gene id: 9755:ADAMTS16
uniprot id: A0A2Y9SHF0
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9755:LOC102992462
gene id: 9755:LOC102992462
uniprot id: A0A455C2H3
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: nucleolus

9755:BICD1
gene id: 9755:BICD1
uniprot id: A0A2Y9T1S4
uniprot id: A0A2Y9T3K0
uniprot id: A0A2Y9T5L6
uniprot id: A0A2Y9TA56
uniprot id: A0A2Y9TA61
uniprot id: A0A455BDD0
uniprot id: A0A455BE03
uniprot id: A0A455BE05
uniprot id: A0A455BE07
uniprot id: A0A455BGE1
names: Similarity
messages: Belongs to the BicD family.

9755:ANKS4B
gene id: 9755:ANKS4B
uniprot id: A0A455C339
names: Function
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

9755:LRP10
gene id: 9755:LRP10
uniprot id: A0A2Y9EES4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:MMS19
gene id: 9755:MMS19
uniprot id: A0A455AJS7
uniprot id: A0A455ALC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MET18/MMS19 family.
messages: Component of the CIA complex.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.
messages: Nucleus
messages: spindle

9755:LOC102981900
gene id: 9755:LOC102981900
uniprot id: A0A2Y9SYR9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9755:FCF1
gene id: 9755:FCF1
uniprot id: A0A2Y9F8D5
uniprot id: A0A455C7W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP23/FCF1 family. FCF1 subfamily.
messages: nucleolus

9755:TMEM138
gene id: 9755:TMEM138
uniprot id: A0A2Y9ENU6
uniprot id: A0A2Y9EQ82
uniprot id: A0A455C9B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM138 family.
messages: Membrane
messages: Required for ciliogenesis.
messages: Vacuole membrane
messages: cilium

9755:SLC25A6
gene id: 9755:SLC25A6
uniprot id: A0A2Y9S538
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

9755:BTC
gene id: 9755:BTC
uniprot id: A0A2Y9F4A5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:MYCL
gene id: 9755:MYCL
uniprot id: A0A2Y9T0C6
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

9755:RGMA
gene id: 9755:RGMA
uniprot id: A0A2Y9RVU7
uniprot id: A0A455BSQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

9755:RUVBL1
gene id: 9755:RUVBL1
uniprot id: A0A2Y9S3D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Dynein axonemal particle
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

9755:RPL11
gene id: 9755:RPL11
uniprot id: A0A2Y9FET9
uniprot id: A0A2Y9SSD6
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.

9755:PELO
gene id: 9755:PELO
uniprot id: A0A455BIX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Component of the Pelota-HBS1L complex, a complex that recognizes stalled ribosomes and triggers the No-Go Decay (NGD) pathway. In the Pelota-HBS1L complex, pelo recognizes ribosomes stalled at the 3' end of an mRNA and engages stalled ribosomes by destabilizing mRNA in the mRNA channel.
messages: Cytoplasm

9755:DCBLD1
gene id: 9755:DCBLD1
uniprot id: A0A455BN15
uniprot id: A0A455BN20
uniprot id: A0A455BR53
uniprot id: A0A455BR59
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:HDHD2
gene id: 9755:HDHD2
uniprot id: A0A2Y9FHC4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

9755:CNNM1
gene id: 9755:CNNM1
uniprot id: A0A2Y9FA93
uniprot id: A0A2Y9SIP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Cell membrane
messages: Membrane
messages: Metal transporter.

9755:STAB2
gene id: 9755:STAB2
uniprot id: A0A2Y9EVK5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:TDRD5
gene id: 9755:TDRD5
uniprot id: A0A2Y9EU23
uniprot id: A0A2Y9EU80
uniprot id: A0A2Y9EV97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDRD5 family.
messages: Cytoplasm
messages: Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body (CB) assembly.

9755:LOC102992933
gene id: 9755:LOC102992933
uniprot id: A0A455AFP8
names: Subcellular Location Annotation
messages: Nucleus

9755:LNPEP
gene id: 9755:LNPEP
uniprot id: A0A2Y9SMU2
uniprot id: A0A455BIX2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Membrane

9755:TRMT1
gene id: 9755:TRMT1
uniprot id: A0A2Y9EIU9
uniprot id: A0A2Y9EJK5
uniprot id: A0A2Y9TIN8
uniprot id: A0A2Y9TK61
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.

9755:PPP1CC
gene id: 9755:PPP1CC
uniprot id: A0A455AI50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: nucleolus
messages: nucleoplasm

9755:EFEMP1
gene id: 9755:EFEMP1
uniprot id: A0A2Y9S8B2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:LHX1
gene id: 9755:LHX1
uniprot id: A0A2Y9EDY4
names: Subcellular Location Annotation
messages: Nucleus

9755:FAM167A
gene id: 9755:FAM167A
uniprot id: A0A2Y9FPS2
names: Similarity
messages: Belongs to the FAM167 (SEC) family.

9755:NODAL
gene id: 9755:NODAL
uniprot id: A0A2Y9FE89
names: Similarity
messages: Belongs to the TGF-beta family.

9755:SUSD5
gene id: 9755:SUSD5
uniprot id: A0A455AG84
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:FAM83B
gene id: 9755:FAM83B
uniprot id: A0A2Y9F5K8
names: Similarity
messages: Belongs to the FAM83 family.

9755:DIS3L2
gene id: 9755:DIS3L2
uniprot id: A0A2Y9FKK5
uniprot id: A0A455API7
uniprot id: A0A455ARD1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mitosis, and negatively regulates cell proliferation.
messages: Belongs to the RNR ribonuclease family.
messages: Belongs to the RNR ribonuclease family. DIS3L2 subfamily.
messages: Cytoplasm
messages: P-body
messages: Specifically recognizes and binds polyuridylated RNAs via 3 RNA-binding regions (named U-zone 1, U-zone 2 and U-zone 3) that form an open funnel on one face of the catalytic domain, allowing RNA to navigate a path to the active site.

9755:PPM1G
gene id: 9755:PPM1G
uniprot id: A0A2Y9EU94
uniprot id: A0A455BUP0
names: Similarity
messages: Belongs to the PP2C family.

9755:DPAGT1
gene id: 9755:DPAGT1
uniprot id: A0A2Y9FIX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family.
messages: Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol.
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:BPNT1
gene id: 9755:BPNT1
uniprot id: A0A2Y9T837
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

9755:PDC
gene id: 9755:PDC
uniprot id: A0A2Y9F9G1
names: Similarity
messages: Belongs to the phosducin family.

9755:ETFB
gene id: 9755:ETFB
uniprot id: A0A2Y9F2I8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

9755:TTC19
gene id: 9755:TTC19
uniprot id: A0A2Y9T2C1
names: Similarity
messages: Belongs to the TTC19 family.

9755:QTRT2
gene id: 9755:QTRT2
uniprot id: A0A2Y9ES46
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Heterodimer of a catalytic subunit QTRT1 and an accessory subunit QTRT2.
messages: Mitochondrion outer membrane
messages: Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).

9755:SYN2
gene id: 9755:SYN2
uniprot id: A0A2Y9SN58
uniprot id: A0A455AEW5
uniprot id: A0A455AFT0
names: Similarity
messages: Belongs to the synapsin family.

9755:LOC102988905
gene id: 9755:LOC102988905
uniprot id: A0A2Y9FRR4
names: Similarity
messages: Belongs to the actin family.

9755:SPC25
gene id: 9755:SPC25
uniprot id: A0A2Y9FHX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC25 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

9755:ACTR1B
gene id: 9755:ACTR1B
uniprot id: A0A2Y9T7W7
names: Similarity
messages: Belongs to the actin family.

9755:DNAJC25
gene id: 9755:DNAJC25
uniprot id: A0A2Y9F0H3
uniprot id: A0A455BKQ3
names: Similarity
messages: Belongs to the DNAJC25 family.

9755:LOX
gene id: 9755:LOX
uniprot id: A0A2Y9F6V7
uniprot id: A0A2Y9SGK3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

9755:LOC112065978
gene id: 9755:LOC112065978
uniprot id: A0A2Y9SZE8
names: Function
messages: Converts protoheme IX and farnesyl diphosphate to heme O.

9755:MARCO
gene id: 9755:MARCO
uniprot id: A0A2Y9RWY1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:CARTPT
gene id: 9755:CARTPT
uniprot id: A0A2Y9FT31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

9755:PLD4
gene id: 9755:PLD4
uniprot id: A0A2Y9EDG1
uniprot id: A0A2Y9T921
names: Similarity
messages: Belongs to the phospholipase D family.

9755:DMRT3
gene id: 9755:DMRT3
uniprot id: A0A2Y9FRK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

9755:PDE5A
gene id: 9755:PDE5A
uniprot id: A0A2Y9SCB0
uniprot id: A0A2Y9SF74
uniprot id: A0A455BW46
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9755:STK3
gene id: 9755:STK3
uniprot id: A0A2Y9S711
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Nucleus

9755:CELF6
gene id: 9755:CELF6
uniprot id: A0A2Y9T704
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Nucleus

9755:AFF1
gene id: 9755:AFF1
uniprot id: A0A2Y9S5R3
uniprot id: A0A455BFC8
uniprot id: A0A455BFV5
uniprot id: A0A455BG02
uniprot id: A0A455BIF0
uniprot id: A0A455BV22
names: Similarity
messages: Belongs to the AF4 family.

9755:SLC10A2
gene id: 9755:SLC10A2
uniprot id: A0A2Y9EVV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

9755:TMEM178A
gene id: 9755:TMEM178A
uniprot id: A0A2Y9SDE3
names: Similarity
messages: Belongs to the TMEM178 family.

9755:P2RX5
gene id: 9755:P2RX5
uniprot id: A0A2Y9T5P5
uniprot id: A0A455CA32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

9755:EXO1
gene id: 9755:EXO1
uniprot id: A0A2Y9ERZ7
uniprot id: A0A2Y9ETG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.
messages: Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Nucleus

9755:PBX2
gene id: 9755:PBX2
uniprot id: A0A2Y9SH16
uniprot id: A0A2Y9SPR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

9755:B3GALT2
gene id: 9755:B3GALT2
uniprot id: A0A2Y9F7U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9755:CD6
gene id: 9755:CD6
uniprot id: A0A2Y9THQ3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:LEO1
gene id: 9755:LEO1
uniprot id: A0A2Y9T2I7
uniprot id: A0A455BS11
names: Similarity
messages: Belongs to the LEO1 family.

9755:LPAR3
gene id: 9755:LPAR3
uniprot id: A0A2Y9F670
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9755:MATN3
gene id: 9755:MATN3
uniprot id: A0A2Y9S6U9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:VIPR2
gene id: 9755:VIPR2
uniprot id: A0A2Y9TC81
uniprot id: A0A2Y9TG63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

9755:GRM5
gene id: 9755:GRM5
uniprot id: A0A2Y9T9C8
uniprot id: A0A2Y9TBA0
uniprot id: A0A2Y9TCX8
uniprot id: A0A2Y9TF98
uniprot id: A0A2Y9TH00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

9755:TBX19
gene id: 9755:TBX19
uniprot id: A0A2Y9F446
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9755:MC3R
gene id: 9755:MC3R
uniprot id: A0A2Y9T8J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane

9755:HOXA7
gene id: 9755:HOXA7
uniprot id: A0A2Y9F114
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

9755:PSMG2
gene id: 9755:PSMG2
uniprot id: A0A2Y9SHC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PSMG2 family.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1.
messages: Forms a heterodimer with PSMG1.

9755:LOC102976718
gene id: 9755:LOC102976718
uniprot id: A0A2Y9F5G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9755:NAA60
gene id: 9755:NAA60
uniprot id: A0A2Y9SPK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA60 subfamily.
messages: Golgi apparatus membrane

9755:ZC3H12C
gene id: 9755:ZC3H12C
uniprot id: A0A2Y9T9W5
uniprot id: A0A2Y9TBB5
names: Similarity
messages: Belongs to the ZC3H12 family.

9755:TTC36
gene id: 9755:TTC36
uniprot id: A0A2Y9FKS8
names: Similarity
messages: Belongs to the TTC36 family.

9755:CDH6
gene id: 9755:CDH6
uniprot id: A0A2Y9SVF3
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

9755:SLC9A3
gene id: 9755:SLC9A3
uniprot id: A0A2Y9SNE1
uniprot id: A0A2Y9STL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Membrane
messages: Recycling endosome membrane

9755:LOC102978094
gene id: 9755:LOC102978094
uniprot id: A0A2Y9SGY2
uniprot id: A0A2Y9SII2
names: Similarity
messages: Belongs to the cytochrome P450 family.

9755:EMC7
gene id: 9755:EMC7
uniprot id: A0A2Y9FRH4
names: Similarity
names: Subunit
messages: Belongs to the EMC7 family.
messages: Component of the ER membrane protein complex (EMC).

9755:LOC102984528
gene id: 9755:LOC102984528
uniprot id: A0A2Y9RWR7
uniprot id: A0A455C5Y6
names: Similarity
messages: Belongs to the actin family.

9755:DTX2
gene id: 9755:DTX2
uniprot id: A0A2Y9ELC0
uniprot id: A0A2Y9ELH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

9755:CACNG7
gene id: 9755:CACNG7
uniprot id: A0A2Y9F2F7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2.

9755:HOXB3
gene id: 9755:HOXB3
uniprot id: A0A2Y9T6S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

9755:ZSCAN20
gene id: 9755:ZSCAN20
uniprot id: A0A2Y9F614
uniprot id: A0A455B1P0
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

9755:NXPH1
gene id: 9755:NXPH1
uniprot id: A0A2Y9EHQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

9755:LOC102992061
gene id: 9755:LOC102992061
uniprot id: A0A2Y9T8P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:PIAS2
gene id: 9755:PIAS2
uniprot id: A0A2Y9ETE9
uniprot id: A0A2Y9EVF1
uniprot id: A0A2Y9TGG1
uniprot id: A0A2Y9THY3
uniprot id: A0A455AIL6
uniprot id: A0A455AIM1
uniprot id: A0A455AIZ6
uniprot id: A0A455AKI4
names: Similarity
messages: Belongs to the PIAS family.

9755:VPS37B
gene id: 9755:VPS37B
uniprot id: A0A2Y9SJ16
uniprot id: A0A455AIY7
uniprot id: A0A455AXE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

9755:SCN3B
gene id: 9755:SCN3B
uniprot id: A0A455C6Y5
uniprot id: A0A455C6Z0
uniprot id: A0A455C759
uniprot id: A0A455C9I1
uniprot id: A0A455CBX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel auxiliary subunit SCN3B (TC 8.A.17) family.
messages: Membrane
messages: Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.

9755:UBIAD1
gene id: 9755:UBIAD1
uniprot id: A0A2Y9FVE3
uniprot id: A0A2Y9STE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Membrane

9755:ATXN3
gene id: 9755:ATXN3
uniprot id: A0A2Y9ELX6
uniprot id: A0A2Y9EM29
uniprot id: A0A2Y9ENB0
uniprot id: A0A455C853
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9755:MED20
gene id: 9755:MED20
uniprot id: A0A455ADN7
uniprot id: A0A455ARF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 20 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

9755:ARHGEF6
gene id: 9755:ARHGEF6
uniprot id: A0A2Y9T0N6
uniprot id: A0A2Y9T570
uniprot id: A0A455AMS9
uniprot id: A0A455AN05
uniprot id: A0A455APV2
uniprot id: A0A455B1K4
names: Subcellular Location Annotation
messages: lamellipodium

9755:VPS72
gene id: 9755:VPS72
uniprot id: A0A2Y9FWV6
names: Function
names: Similarity
messages: Belongs to the VPS72/YL1 family.
messages: Deposition-and-exchange histone chaperone specific for H2AZ1, specifically chaperones H2AZ1 and deposits it into nucleosomes. As component of the SRCAP complex, mediates the ATP-dependent exchange of histone H2AZ1/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling.

9755:HSPA4L
gene id: 9755:HSPA4L
uniprot id: A0A2Y9F1Q5
names: Similarity
messages: Belongs to the heat shock protein 70 family.

9755:LOC102985372
gene id: 9755:LOC102985372
uniprot id: A0A455B772
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9755:CCDC25
gene id: 9755:CCDC25
uniprot id: A0A2Y9FR18
uniprot id: A0A2Y9T6R7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CCDC25 family.
messages: Cell membrane
messages: Endomembrane system
messages: Interacts (via cytoplasmic region) with ILK.

9755:VKORC1L1
gene id: 9755:VKORC1L1
uniprot id: A0A2Y9TKD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:B4GALNT2
gene id: 9755:B4GALNT2
uniprot id: A0A2Y9EWP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Membrane

9755:GALNTL6
gene id: 9755:GALNTL6
uniprot id: A0A2Y9T6N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9755:PPP6R1
gene id: 9755:PPP6R1
uniprot id: A0A2Y9EK99
names: Similarity
messages: Belongs to the SAPS family.

9755:AFG3L2
gene id: 9755:AFG3L2
uniprot id: A0A2Y9SD81
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

9755:CHCHD6
gene id: 9755:CHCHD6
uniprot id: A0A2Y9S3B2
uniprot id: A0A455AFT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MICOS complex subunit Mic19 family. Metazoan Mic25 subfamily.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Membrane
messages: Mitochondrion inner membrane

9755:FGF4
gene id: 9755:FGF4
uniprot id: A0A2Y9TH28
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9755:DYNC1I1
gene id: 9755:DYNC1I1
uniprot id: A0A455BD21
uniprot id: A0A455BPN5
names: Similarity
messages: Belongs to the dynein intermediate chain family.

9755:ODF2
gene id: 9755:ODF2
uniprot id: A0A2Y9EGS7
uniprot id: A0A2Y9EGS9
uniprot id: A0A2Y9EHG3
uniprot id: A0A2Y9EHG8
uniprot id: A0A2Y9EI58
uniprot id: A0A2Y9EIN4
uniprot id: A0A2Y9STK9
uniprot id: A0A2Y9SUZ4
uniprot id: A0A2Y9SXE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

9755:ALX4
gene id: 9755:ALX4
uniprot id: A0A2Y9FLV2
names: Subcellular Location Annotation
messages: Nucleus

9755:DNASE1L1
gene id: 9755:DNASE1L1
uniprot id: A0A2Y9FCX9
names: Similarity
messages: Belongs to the DNase I family.

9755:LOC102989866
gene id: 9755:LOC102989866
uniprot id: A0A2Y9RX98
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

9755:SLC25A43
gene id: 9755:SLC25A43
uniprot id: A0A2Y9T788
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9755:LOC102979308
gene id: 9755:LOC102979308
uniprot id: A0A2Y9TAR4
names: Similarity
messages: Belongs to the serpin family.

9755:NUP50
gene id: 9755:NUP50
uniprot id: A0A2Y9SY58
names: Subcellular Location Annotation
messages: nuclear pore complex

9755:EIF3B
gene id: 9755:EIF3B
uniprot id: A0A2Y9FUY3
uniprot id: A0A455BZK6
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit B family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Also interacts with UPF2. Interacts with METTL3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.
messages: Cytoplasm
messages: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: The RRM domain mediates interaction with EIF3J.

9755:LOC102994874
gene id: 9755:LOC102994874
uniprot id: A0A2Y9RZK6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Secreted

9755:ST6GAL2
gene id: 9755:ST6GAL2
uniprot id: A0A2Y9S4T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9755:FAM135B
gene id: 9755:FAM135B
uniprot id: A0A2Y9TAZ2
names: Similarity
messages: Belongs to the FAM135 family.

9755:DUSP6
gene id: 9755:DUSP6
uniprot id: A0A2Y9EJ38
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

9755:LOC102976944
gene id: 9755:LOC102976944
uniprot id: A0A2Y9EHS1
names: Similarity
messages: Belongs to the globin family.

9755:LOC102995098
gene id: 9755:LOC102995098
uniprot id: A0A2Y9F7F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

9755:SSH2
gene id: 9755:SSH2
uniprot id: A0A2Y9FI32
uniprot id: A0A2Y9FI33
uniprot id: A0A2Y9FIK7
uniprot id: A0A2Y9FKA1
uniprot id: A0A455BXN0
uniprot id: A0A455BYH3
uniprot id: A0A455C1B4
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

9755:RPRD1B
gene id: 9755:RPRD1B
uniprot id: A0A2Y9T3I8
names: Function
names: Similarity
names: Subunit
messages: Associates with the RNA polymerase II complex.
messages: Belongs to the UPF0400 (RTT103) family.
messages: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD.

9755:GPR89A
gene id: 9755:GPR89A
uniprot id: A0A2Y9FUG7
uniprot id: A0A2Y9SAC5
uniprot id: A0A455B6Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Golgi pH regulator (TC 1.A.38) family.
messages: Membrane

9755:DACT1
gene id: 9755:DACT1
uniprot id: A0A2Y9S209
uniprot id: A0A2Y9SA07
names: Similarity
messages: Belongs to the dapper family.

9755:C6
gene id: 9755:C6
uniprot id: A0A2Y9F0S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Secreted

9755:LOC102991840
gene id: 9755:LOC102991840
uniprot id: A0A2Y9FQN6
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Component of the large ribosomal subunit.

9755:RETNLB
gene id: 9755:RETNLB
uniprot id: A0A2Y9FDR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistin/FIZZ family.
messages: Secreted

9755:HABP4
gene id: 9755:HABP4
uniprot id: A0A2Y9TCQ0
names: Similarity
messages: Belongs to the SERBP1-HABP4 family.

9755:GNB1
gene id: 9755:GNB1
uniprot id: A0A2Y9SRE5
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

9755:IFIH1
gene id: 9755:IFIH1
uniprot id: A0A2Y9EMC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

9755:OAS2
gene id: 9755:OAS2
uniprot id: A0A2Y9EL90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-5A synthase family.
messages: Cytoplasm

9755:CETN1
gene id: 9755:CETN1
uniprot id: A0A2Y9ERW3
names: Similarity
messages: Belongs to the centrin family.

9755:LHX4
gene id: 9755:LHX4
uniprot id: A0A2Y9EL82
names: Subcellular Location Annotation
messages: Nucleus

9755:NDUFS4
gene id: 9755:NDUFS4
uniprot id: A0A2Y9SXA8
uniprot id: A0A455BIP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS4 subunit family.
messages: Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.
messages: Mitochondrion inner membrane

9755:ATP10B
gene id: 9755:ATP10B
uniprot id: A0A2Y9F615
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

9755:MAGOH
gene id: 9755:MAGOH
uniprot id: A0A2Y9FQ23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mago nashi family.
messages: Nucleus

9755:LOC102990567
gene id: 9755:LOC102990567
uniprot id: A0A2Y9F6W3
names: Similarity
messages: Belongs to the cytochrome b5 family.

9755:CA4
gene id: 9755:CA4
uniprot id: A0A455C1Y3
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

9755:SRP72
gene id: 9755:SRP72
uniprot id: A0A2Y9F6D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP72 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
messages: Cytoplasm

9755:HYAL4
gene id: 9755:HYAL4
uniprot id: A0A2Y9EFB1
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

9755:PAQR4
gene id: 9755:PAQR4
uniprot id: A0A2Y9SL90
uniprot id: A0A2Y9SPQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

9755:THRSP
gene id: 9755:THRSP
uniprot id: A0A2Y9EQN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

9755:LOC112064628
gene id: 9755:LOC112064628
uniprot id: A0A2Y9SIL6
names: Similarity
messages: Belongs to the dapper family.

9755:LOC102988543
gene id: 9755:LOC102988543
uniprot id: A0A2Y9TCJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

9755:VILL
gene id: 9755:VILL
uniprot id: A0A455AE88
uniprot id: A0A455AEP2
uniprot id: A0A455AGN9
uniprot id: A0A455AS24
names: Similarity
messages: Belongs to the villin/gelsolin family.

9755:NRF1
gene id: 9755:NRF1
uniprot id: A0A2Y9T202
uniprot id: A0A2Y9TAG1
uniprot id: A0A455B9C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRF1/Ewg family.
messages: Nucleus

9755:CPLX2
gene id: 9755:CPLX2
uniprot id: A0A2Y9F0L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

9755:ST8SIA2
gene id: 9755:ST8SIA2
uniprot id: A0A2Y9RVX5
uniprot id: A0A455BTA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9755:HACD4
gene id: 9755:HACD4
uniprot id: A0A2Y9FBD6
uniprot id: A0A2Y9FDD2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:PKMYT1
gene id: 9755:PKMYT1
uniprot id: A0A2Y9ECV1
names: Similarity
messages: Belongs to the protein kinase superfamily.

9755:SGTB
gene id: 9755:SGTB
uniprot id: A0A2Y9EIA7
uniprot id: A0A2Y9EJ17
uniprot id: A0A2Y9EKD2
names: Similarity
messages: Belongs to the SGT family.

9755:VDAC1
gene id: 9755:VDAC1
uniprot id: A0A2Y9SDC8
names: Similarity
messages: Belongs to the eukaryotic mitochondrial porin family.

9755:NOS3
gene id: 9755:NOS3
uniprot id: A0A2Y9FMB5
uniprot id: A0A2Y9T1B5
uniprot id: A0A455BBQ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NOS family.
messages: Binds 1 FAD.
messages: Binds 1 FMN.
messages: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.

9755:PSMB8
gene id: 9755:PSMB8
uniprot id: A0A2Y9ETF9
uniprot id: A0A455AG70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

9755:SMAD1
gene id: 9755:SMAD1
uniprot id: A0A2Y9T0I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

9755:CBLB
gene id: 9755:CBLB
uniprot id: A0A2Y9SHX2
uniprot id: A0A2Y9SJJ1
names: Domain
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

9755:TCF7
gene id: 9755:TCF7
uniprot id: A0A2Y9SP57
uniprot id: A0A2Y9SRL8
uniprot id: A0A2Y9SWE5
uniprot id: A0A455BME2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

9755:NPBWR2
gene id: 9755:NPBWR2
uniprot id: A0A2Y9FUT7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9755:FARSB
gene id: 9755:FARSB
uniprot id: A0A2Y9SNQ3
uniprot id: A0A2Y9SWY7
names: Similarity
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.

9755:B3GALT9
gene id: 9755:B3GALT9
uniprot id: A0A2Y9SVN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9755:DCAF13
gene id: 9755:DCAF13
uniprot id: A0A2Y9FBR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DCAF13/WDSOF1 family.
messages: nucleolus

9755:PEX19
gene id: 9755:PEX19
uniprot id: A0A2Y9FUB2
uniprot id: A0A2Y9RZU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxin-19 family.
messages: Interacts with a broad range of peroxisomal membrane proteins, including PEX3, PEX10, PEX11A, PEX11B, PEX12, PEX13, PEX14 and PEX16, PXMP2/PMP22, PXMP4/PMP24, SLC25A17/PMP34, ABCD1/ALDP, ABCD2/ALDRP, and ABCD3/PMP70. Also interacts with the tumor suppressor CDKN2A/p19ARF.
messages: Membrane
messages: Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53.
messages: Peroxisome membrane

9755:SOD3
gene id: 9755:SOD3
uniprot id: A0A2Y9FLS3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

9755:LAPTM5
gene id: 9755:LAPTM5
uniprot id: A0A2Y9FQB4
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

9755:DRD1
gene id: 9755:DRD1
uniprot id: A0A2Y9F3K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
messages: Membrane
messages: dendritic spine

9755:SCAP
gene id: 9755:SCAP
uniprot id: A0A2Y9SVF7
uniprot id: A0A455AD97
uniprot id: A0A455AQW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SCAP family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

9755:SLC35D2
gene id: 9755:SLC35D2
uniprot id: A0A2Y9TEF1
uniprot id: A0A455BM03
names: Subcellular Location Annotation
messages: Membrane

9755:YKT6
gene id: 9755:YKT6
uniprot id: A0A2Y9FLL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.

9755:CTSD
gene id: 9755:CTSD
uniprot id: A0A2Y9SC19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Lysosome
messages: extracellular space

9755:SUCLA2
gene id: 9755:SUCLA2
uniprot id: A0A2Y9EIG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
messages: Belongs to the succinate/malate CoA ligase beta subunit family. ATP-specific subunit beta subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for ATP.
messages: Mitochondrion

9755:TAF10
gene id: 9755:TAF10
uniprot id: A0A2Y9SGB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF10 family.
messages: Nucleus
messages: The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription.

9755:C6H12orf75
gene id: 9755:C6H12orf75
uniprot id: A0A2Y9T0X0
names: Similarity
messages: Belongs to the OCC1 family.

9755:LOC112067454
gene id: 9755:LOC112067454
uniprot id: A0A2Y9TG51
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:CD48
gene id: 9755:CD48
uniprot id: A0A2Y9S7B9
names: Subcellular Location Annotation
messages: Membrane

9755:GLRA2
gene id: 9755:GLRA2
uniprot id: A0A2Y9FB02
uniprot id: A0A2Y9FB05
uniprot id: A0A2Y9FD04
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

9755:PATJ
gene id: 9755:PATJ
uniprot id: A0A455B843
uniprot id: A0A455B8K8
uniprot id: A0A455B8Y0
uniprot id: A0A455B8Y4
uniprot id: A0A455BAY7
uniprot id: A0A455BAZ3
uniprot id: A0A455BAZ9
uniprot id: A0A455BML2
names: Subcellular Location Annotation
messages: Cell membrane
messages: tight junction

9755:ADGRA1
gene id: 9755:ADGRA1
uniprot id: A0A2Y9SLK7
names: Subcellular Location Annotation
messages: Membrane

9755:IPO13
gene id: 9755:IPO13
uniprot id: A0A2Y9F180
uniprot id: A0A455AWM5
uniprot id: A0A455AYJ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the importin beta family.
messages: Cytoplasm
messages: Interacts with UBC9, RAN, RBM8A, eIF-1A and PAX6.
messages: Nucleus

9755:UBE2E1
gene id: 9755:UBE2E1
uniprot id: A0A2Y9S0B5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9755:HOXA11
gene id: 9755:HOXA11
uniprot id: A0A2Y9F0S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

9755:PABPC4
gene id: 9755:PABPC4
uniprot id: A0A2Y9SZF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

9755:DHRS3
gene id: 9755:DHRS3
uniprot id: A0A2Y9FSH4
uniprot id: A0A2Y9SVU4
uniprot id: A0A455B4X7
uniprot id: A0A455BI52
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9755:TMED2
gene id: 9755:TMED2
uniprot id: A0A2Y9FLZ8
uniprot id: A0A455AHT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

9755:SEZ6L2
gene id: 9755:SEZ6L2
uniprot id: A0A2Y9ERM9
uniprot id: A0A2Y9ESF8
uniprot id: A0A455BZV1
uniprot id: A0A455BZV6
uniprot id: A0A455C3Z2
uniprot id: A0A455CAG1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:DPYS
gene id: 9755:DPYS
uniprot id: A0A2Y9T448
uniprot id: A0A2Y9TCG1
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

9755:ENO1
gene id: 9755:ENO1
uniprot id: A0A2Y9EXF5
uniprot id: A0A455B6Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

9755:TERF2
gene id: 9755:TERF2
uniprot id: A0A2Y9SQX1
uniprot id: A0A2Y9SY14
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.
messages: Homodimer.
messages: Nucleus
messages: telomere

9755:CAMSAP1
gene id: 9755:CAMSAP1
uniprot id: A0A2Y9STQ8
uniprot id: A0A2Y9SV45
uniprot id: A0A2Y9SZQ0
uniprot id: A0A455BVV5
uniprot id: A0A455BVV6
uniprot id: A0A455BZC2
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

9755:RIPOR2
gene id: 9755:RIPOR2
uniprot id: A0A2Y9F6W2
uniprot id: A0A2Y9F6X3
uniprot id: A0A455AFE3
uniprot id: A0A455AGQ1
names: Similarity
messages: Belongs to the RIPOR family.

9755:TOMM40L
gene id: 9755:TOMM40L
uniprot id: A0A2Y9EZL0
uniprot id: A0A2Y9EZV0
uniprot id: A0A2Y9S742
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

9755:LOC102978941
gene id: 9755:LOC102978941
uniprot id: A0A2Y9S5D4
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

9755:MFF
gene id: 9755:MFF
uniprot id: A0A2Y9FMP2
uniprot id: A0A2Y9FMP6
uniprot id: A0A2Y9FMV4
uniprot id: A0A2Y9FN69
uniprot id: A0A2Y9FPE1
uniprot id: A0A2Y9FPE6
uniprot id: A0A2Y9FQ79
uniprot id: A0A455APW3
uniprot id: A0A455B214
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tango11 family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Peroxisome
messages: Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface.
messages: synaptic vesicle

9755:RNFT2
gene id: 9755:RNFT2
uniprot id: A0A2Y9FQ78
uniprot id: A0A455AI58
uniprot id: A0A455AJM0
uniprot id: A0A455AJS5
uniprot id: A0A455AW11
names: Subcellular Location Annotation
messages: Membrane

9755:ZSCAN5B
gene id: 9755:ZSCAN5B
uniprot id: A0A2Y9F4U7
names: Subcellular Location Annotation
messages: Nucleus

9755:LOC112067434
gene id: 9755:LOC112067434
uniprot id: A0A2Y9TFK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIII family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

9755:CXCL13
gene id: 9755:CXCL13
uniprot id: A0A455BG21
uniprot id: A0A455BG75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

9755:CCNB1
gene id: 9755:CCNB1
uniprot id: A0A2Y9FT05
names: Function
names: Similarity
messages: Belongs to the cyclin family.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.

9755:GIPC2
gene id: 9755:GIPC2
uniprot id: A0A2Y9SAQ5
names: Similarity
messages: Belongs to the GIPC family.

9755:LOC102981487
gene id: 9755:LOC102981487
uniprot id: A0A2Y9FUA0
uniprot id: A0A455B998
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:TSC22D4
gene id: 9755:TSC22D4
uniprot id: A0A2Y9EYZ6
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

9755:BMP5
gene id: 9755:BMP5
uniprot id: A0A2Y9EU58
uniprot id: A0A2Y9SPT3
names: Similarity
messages: Belongs to the TGF-beta family.

9755:LOC112064110
gene id: 9755:LOC112064110
uniprot id: A0A2Y9SMB8
names: Function
names: Similarity
messages: Belongs to the E(R) family.
messages: May have a role in the cell cycle.

9755:CCN5
gene id: 9755:CCN5
uniprot id: A0A2Y9T089
uniprot id: A0A2Y9T698
names: Similarity
messages: Belongs to the CCN family.

9755:CDKAL1
gene id: 9755:CDKAL1
uniprot id: A0A2Y9SMI3
uniprot id: A0A455AHS5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
messages: Endoplasmic reticulum membrane

9755:LOC114487991
gene id: 9755:LOC114487991
uniprot id: A0A455CBT0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

9755:LOC112067146
gene id: 9755:LOC112067146
uniprot id: A0A455AIF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: cytoskeleton

9755:LOC102994248
gene id: 9755:LOC102994248
uniprot id: A0A2Y9F0K7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:STAB1
gene id: 9755:STAB1
uniprot id: A0A455AFM5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:LOC102975454
gene id: 9755:LOC102975454
uniprot id: A0A2Y9SCS8
uniprot id: A0A2Y9SKE0
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

9755:AQP5
gene id: 9755:AQP5
uniprot id: A0A2Y9ESN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

9755:ATP5MC2
gene id: 9755:ATP5MC2
uniprot id: A0A2Y9SKA5
uniprot id: A0A455BE95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

9755:C16H11orf58
gene id: 9755:C16H11orf58
uniprot id: A0A2Y9EN61
names: Similarity
messages: Belongs to the SMAP family.

9755:LOC112066595
gene id: 9755:LOC112066595
uniprot id: A0A2Y9T5C9
uniprot id: A0A455C0U3
uniprot id: A0A455C0U6
names: Similarity
messages: Belongs to the COG1 family.

9755:LOC102989030
gene id: 9755:LOC102989030
uniprot id: A0A2Y9SZ76
names: Similarity
messages: Belongs to the heat shock protein 70 family.

9755:LOC112064068
gene id: 9755:LOC112064068
uniprot id: A0A2Y9SKS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

9755:TREX2
gene id: 9755:TREX2
uniprot id: A0A455API1
names: Similarity
messages: Belongs to the exonuclease superfamily. TREX family.

9755:GGTA1
gene id: 9755:GGTA1
uniprot id: A0A2Y9STG0
uniprot id: A0A2Y9SX89
uniprot id: A0A455BKU7
uniprot id: A0A455BNC7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Membrane

9755:HOXC8
gene id: 9755:HOXC8
uniprot id: A0A2Y9FN48
names: Subcellular Location Annotation
messages: Nucleus

9755:RFNG
gene id: 9755:RFNG
uniprot id: A0A2Y9FLV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9755:HAX1
gene id: 9755:HAX1
uniprot id: A0A2Y9FTR5
names: Function
names: Similarity
messages: Belongs to the HAX1 family.
messages: Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools.

9755:MED23
gene id: 9755:MED23
uniprot id: A0A2Y9SPH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 23 family.
messages: Nucleus

9755:LOC102987948
gene id: 9755:LOC102987948
uniprot id: A0A2Y9ENS5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9755:RNF170
gene id: 9755:RNF170
uniprot id: A0A2Y9T8D3
uniprot id: A0A2Y9TBV2
uniprot id: A0A2Y9TG54
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:LOC102988804
gene id: 9755:LOC102988804
uniprot id: A0A2Y9T8L4
names: Similarity
messages: Belongs to the glycosyl hydrolase 59 family.

9755:MEOX1
gene id: 9755:MEOX1
uniprot id: A0A2Y9FPG8
names: Subcellular Location Annotation
messages: Nucleus

9755:CTDP1
gene id: 9755:CTDP1
uniprot id: A0A2Y9THL4
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: This promotes the activity of RNA polymerase II.

9755:LOC102990226
gene id: 9755:LOC102990226
uniprot id: A0A2Y9SXX3
names: Subcellular Location Annotation
messages: Nucleus

9755:CSTA
gene id: 9755:CSTA
uniprot id: A0A2Y9F030
names: Similarity
messages: Belongs to the cystatin family.

9755:MRPL15
gene id: 9755:MRPL15
uniprot id: A0A2Y9FG72
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

9755:LOC102975124
gene id: 9755:LOC102975124
uniprot id: A0A455BJX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

9755:SLC24A2
gene id: 9755:SLC24A2
uniprot id: A0A2Y9SV38
uniprot id: A0A2Y9SYY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

9755:RAD50
gene id: 9755:RAD50
uniprot id: A0A2Y9SES1
uniprot id: A0A2Y9SET0
names: Similarity
messages: Belongs to the SMC family. RAD50 subfamily.

9755:TPM1
gene id: 9755:TPM1
uniprot id: A0A2Y9T0P0
uniprot id: A0A2Y9T0P7
uniprot id: A0A2Y9T4E6
uniprot id: A0A2Y9T4F0
uniprot id: A0A2Y9T6R0
uniprot id: A0A2Y9T8T6
uniprot id: A0A455BNZ0
uniprot id: A0A455C417
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

9755:MAPK8
gene id: 9755:MAPK8
uniprot id: A0A2Y9EPS4
uniprot id: A0A455AMA8
uniprot id: A0A455AP52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

9755:ATXN1L
gene id: 9755:ATXN1L
uniprot id: A0A2Y9F5X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

9755:LOC102994350
gene id: 9755:LOC102994350
uniprot id: A0A2Y9TGU0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

9755:DYNC2H1
gene id: 9755:DYNC2H1
uniprot id: A0A2Y9RX12
names: Similarity
messages: Belongs to the dynein heavy chain family.

9755:MAP2K5
gene id: 9755:MAP2K5
uniprot id: A0A2Y9T0Q8
uniprot id: A0A2Y9T4F6
uniprot id: A0A455BSF3
names: Similarity
messages: Belongs to the protein kinase superfamily.

9755:IDUA
gene id: 9755:IDUA
uniprot id: A0A455BH26
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

9755:NKX6-1
gene id: 9755:NKX6-1
uniprot id: A0A2Y9EQ51
names: Subcellular Location Annotation
messages: Nucleus

9755:NIPA2
gene id: 9755:NIPA2
uniprot id: A0A2Y9S993
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

9755:RNPEP
gene id: 9755:RNPEP
uniprot id: A0A2Y9T9U0
uniprot id: A0A455B5G2
uniprot id: A0A455B5Z8
uniprot id: A0A455B7R0
uniprot id: A0A455BJC2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

9755:LOC102993329
gene id: 9755:LOC102993329
uniprot id: A0A2Y9F322
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9755:ONECUT2
gene id: 9755:ONECUT2
uniprot id: A0A2Y9EF86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

9755:CACNA1C
gene id: 9755:CACNA1C
uniprot id: A0A2Y9T1D3
uniprot id: A0A455BCX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. CACNA1C subfamily.
messages: Cell membrane
messages: Membrane
messages: Perikaryon
messages: Postsynaptic density membrane
messages: T-tubule
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death.
messages: dendrite
messages: sarcolemma

9755:TEAD4
gene id: 9755:TEAD4
uniprot id: A0A455BCL0
uniprot id: A0A455BD87
names: Subcellular Location Annotation
messages: Nucleus

9755:CCNH
gene id: 9755:CCNH
uniprot id: A0A2Y9SU51
uniprot id: A0A455BJ38
names: Function
names: Similarity
names: Subunit
messages: Associates primarily with CDK7 and MAT1 to form the CAK complex. CAK can further associate with the core-TFIIH to form the TFIIH basal transcription factor.
messages: Belongs to the cyclin family. Cyclin C subfamily.
messages: Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

9755:TGFB1I1
gene id: 9755:TGFB1I1
uniprot id: A0A2Y9F4T2
uniprot id: A0A2Y9F4X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paxillin family.
messages: cytoskeleton
messages: focal adhesion

9755:C3AR1
gene id: 9755:C3AR1
uniprot id: A0A2Y9FBF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Interacts with VGF-derived peptide TLQP-21.
messages: Membrane
messages: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.

9755:MEGF8
gene id: 9755:MEGF8
uniprot id: A0A2Y9EH50
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:TJAP1
gene id: 9755:TJAP1
uniprot id: A0A2Y9SM38
uniprot id: A0A455AHZ5
names: Subcellular Location Annotation
messages: Membrane

9755:NUDCD1
gene id: 9755:NUDCD1
uniprot id: A0A2Y9F3Y7
uniprot id: A0A2Y9TAZ7
uniprot id: A0A455C5N6
uniprot id: A0A455C8J3
uniprot id: A0A455CBF7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9755:LOC112066110
gene id: 9755:LOC112066110
uniprot id: A0A2Y9T2Q0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

9755:SNRPC
gene id: 9755:SNRPC
uniprot id: A0A2Y9EP42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the U1 small nuclear ribonucleoprotein C family.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. snrpc/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates E complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Nucleus
messages: U1 snRNP is composed of the 7 core Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins SNRNP70/U1-70K, SNRPA/U1-A and SNRPC/U1-C. SNRPC/U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA.

9755:LOC112067642
gene id: 9755:LOC112067642
uniprot id: A0A2Y9TJW2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:TENM3
gene id: 9755:TENM3
uniprot id: A0A2Y9S2A0
uniprot id: A0A455ALJ1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:P2RY8
gene id: 9755:P2RY8
uniprot id: A0A2Y9FRL6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9755:ATP6V1B2
gene id: 9755:ATP6V1B2
uniprot id: A0A2Y9EJ25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.

9755:CCL5
gene id: 9755:CCL5
uniprot id: A0A455CAX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

9755:CAD
gene id: 9755:CAD
uniprot id: A0A2Y9S888
uniprot id: A0A2Y9SBG0
names: Similarity
messages: In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily.

9755:DIPK2A
gene id: 9755:DIPK2A
uniprot id: A0A2Y9FDY9
uniprot id: A0A455BLM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Secreted

9755:MTMR10
gene id: 9755:MTMR10
uniprot id: A0A455BPU2
uniprot id: A0A455C4W1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

9755:GPAM
gene id: 9755:GPAM
uniprot id: A0A2Y9SMS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipids biosynthesis such as triglycerides, phosphatidic acids and lysophosphatidic acids.
messages: Mitochondrion outer membrane

9755:KCNMB1
gene id: 9755:KCNMB1
uniprot id: A0A2Y9FKW1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KCNMB (TC 8.A.14.1) family.
messages: Interacts with KCNMA1 tetramer. There are probably 4 molecules of KCMNB per KCNMA1 tetramer.
messages: Membrane
messages: N-glycosylated.
messages: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity.

9755:MTMR12
gene id: 9755:MTMR12
uniprot id: A0A2Y9SFY4
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

9755:LOC102988099
gene id: 9755:LOC102988099
uniprot id: A0A2Y9FB32
uniprot id: A0A2Y9FD32
names: Subcellular Location Annotation
messages: Membrane

9755:LOC102988908
gene id: 9755:LOC102988908
uniprot id: A0A2Y9EXP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

9755:QRFP
gene id: 9755:QRFP
uniprot id: A0A2Y9FUT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFamide neuropeptide family.
messages: Secreted

9755:PLK5
gene id: 9755:PLK5
uniprot id: A0A455CBL7
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

9755:OSMR
gene id: 9755:OSMR
uniprot id: A0A2Y9ESL0
uniprot id: A0A2Y9EUI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

9755:GNB4
gene id: 9755:GNB4
uniprot id: A0A2Y9SMX2
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

9755:WDR44
gene id: 9755:WDR44
uniprot id: A0A2Y9EQV8
names: Subcellular Location Annotation
messages: trans-Golgi network

9755:HGF
gene id: 9755:HGF
uniprot id: A0A2Y9RZG7
uniprot id: A0A455BN23
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Dimer of an alpha chain and a beta chain linked by a disulfide bond. Interacts with SRPX2; the interaction increases HGF mitogenic activity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization.

9755:PCID2
gene id: 9755:PCID2
uniprot id: A0A455BWV6
names: Similarity
messages: Belongs to the CSN12 family.

9755:TNFAIP2
gene id: 9755:TNFAIP2
uniprot id: A0A455C899
names: Similarity
messages: Belongs to the SEC6 family.

9755:FGD1
gene id: 9755:FGD1
uniprot id: A0A2Y9FBB8
uniprot id: A0A455ANS9
names: Subcellular Location Annotation
messages: cytoskeleton

9755:CREBL2
gene id: 9755:CREBL2
uniprot id: A0A2Y9T1N4
uniprot id: A0A455BDL5
uniprot id: A0A455BG01
uniprot id: A0A455BSJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Nucleus

9755:NLRP5
gene id: 9755:NLRP5
uniprot id: A0A2Y9F5H3
names: Similarity
messages: Belongs to the NLRP family.

9755:ELMO2
gene id: 9755:ELMO2
uniprot id: A0A2Y9T7X6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

9755:FGF12
gene id: 9755:FGF12
uniprot id: A0A2Y9FL38
uniprot id: A0A2Y9SRL3
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9755:FAR2
gene id: 9755:FAR2
uniprot id: A0A2Y9FDE9
uniprot id: A0A2Y9FFD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acyl-CoA reductase family.
messages: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
messages: Peroxisome membrane

9755:OLFM1
gene id: 9755:OLFM1
uniprot id: A0A2Y9S3J2
uniprot id: A0A2Y9S9Y2
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

9755:TNF
gene id: 9755:TNF
uniprot id: A0A2Y9EW81
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tumor necrosis factor family.
messages: Cell membrane
messages: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces GKAP42 protein degradation in adipocytes which is partially responsible for TNF-induced insulin resistance. Plays a role in angiogenesis by inducing VEGF production synergistically with IL1B and IL6.
messages: Homotrimer. Interacts with SPPL2B.
messages: Membrane
messages: O-glycosylated; glycans contain galactose, N-acetylgalactosamine and N-acetylneuraminic acid.
messages: Secreted
messages: The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.
messages: The membrane form, but not the soluble form, is phosphorylated on serine residues. Dephosphorylation of the membrane form occurs by binding to soluble TNFRSF1A/TNFR1.
messages: The soluble form derives from the membrane form by proteolytic processing. The membrane-bound form is further proteolytically processed by SPPL2A or SPPL2B through regulated intramembrane proteolysis producing TNF intracellular domains (ICD1 and ICD2) released in the cytosol and TNF C-domain 1 and C-domain 2 secreted into the extracellular space.

9755:RIC3
gene id: 9755:RIC3
uniprot id: A0A455AAW8
names: Similarity
messages: Belongs to the ric-3 family.

9755:FOXB1
gene id: 9755:FOXB1
uniprot id: A0A2Y9FBI2
names: Subcellular Location Annotation
messages: Nucleus

9755:FAM229B
gene id: 9755:FAM229B
uniprot id: A0A2Y9FA10
names: Similarity
messages: Belongs to the FAM229 family.

9755:CRYZ
gene id: 9755:CRYZ
uniprot id: A0A2Y9FHL9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

9755:KCNJ13
gene id: 9755:KCNJ13
uniprot id: A0A2Y9FJR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

9755:ADCYAP1R1
gene id: 9755:ADCYAP1R1
uniprot id: A0A2Y9T8X4
names: Subcellular Location Annotation
messages: Membrane

9755:ACVR1
gene id: 9755:ACVR1
uniprot id: A0A2Y9F110
uniprot id: A0A455ACW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

9755:B4GALT1
gene id: 9755:B4GALT1
uniprot id: A0A2Y9F6J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

9755:TAX1BP3
gene id: 9755:TAX1BP3
uniprot id: A0A2Y9FMM7
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: May regulate a number of protein-protein interactions by competing for PDZ domain binding sites.
messages: Nucleus

9755:FEZ1
gene id: 9755:FEZ1
uniprot id: A0A2Y9EQ88
names: Similarity
messages: Belongs to the zygin family.

9755:ATL3
gene id: 9755:ATL3
uniprot id: A0A2Y9TDD9
uniprot id: A0A2Y9TJ29
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

9755:MYSM1
gene id: 9755:MYSM1
uniprot id: A0A2Y9FRN9
uniprot id: A0A2Y9FRR9
uniprot id: A0A2Y9FTJ7
names: Similarity
messages: Belongs to the peptidase M67A family. MYSM1 subfamily.

9755:AARS1
gene id: 9755:AARS1
uniprot id: A0A2Y9EH02
names: Cofactor
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: ISGylated.
messages: Monomer. Interacts with ANKRD16; the interaction is direct.

9755:SCUBE2
gene id: 9755:SCUBE2
uniprot id: A0A455C5B9
uniprot id: A0A455C5C4
uniprot id: A0A455C5L7
uniprot id: A0A455C6C8
uniprot id: A0A455C8V4
uniprot id: A0A455C8V6
uniprot id: A0A455CBL2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9755:LOC102993787
gene id: 9755:LOC102993787
uniprot id: A0A2Y9S3J7
names: Similarity
messages: Belongs to the ficolin lectin family.

9755:FOXL2
gene id: 9755:FOXL2
uniprot id: A0A2Y9TDF8
names: Subcellular Location Annotation
messages: Nucleus

9755:ROMO1
gene id: 9755:ROMO1
uniprot id: A0A2Y9EGD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGR2 family.
messages: Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.
messages: Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation.
messages: Mitochondrion inner membrane

9755:BCAP31
gene id: 9755:BCAP31
uniprot id: A0A2Y9S9W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays a role in the export of secreted proteins in the ER.

9755:PHYHIPL
gene id: 9755:PHYHIPL
uniprot id: A0A455APP1
names: Similarity
messages: Belongs to the PHYHIP family.

9755:ADRA2B
gene id: 9755:ADRA2B
uniprot id: A0A2Y9FAH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.
messages: Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA2B sub-subfamily.
messages: Cell membrane
messages: Membrane

9755:CFAP298
gene id: 9755:CFAP298
uniprot id: A0A2Y9EDX1
uniprot id: A0A2Y9SHY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP298 family.
messages: cilium basal body

9755:SET
gene id: 9755:SET
uniprot id: A0A2Y9EJ43
uniprot id: A0A2Y9SZM4
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9755:C15H8orf82
gene id: 9755:C15H8orf82
uniprot id: A0A2Y9EMR3
names: Similarity
messages: Belongs to the UPF0598 family.

9755:BLOC1S2
gene id: 9755:BLOC1S2
uniprot id: A0A2Y9F9M2
names: Similarity
messages: Belongs to the BLOC1S2 family.

9755:PDIK1L
gene id: 9755:PDIK1L
uniprot id: A0A2Y9EY66
uniprot id: A0A2Y9SS35
names: Similarity
messages: Belongs to the protein kinase superfamily.

9755:LOC102975790
gene id: 9755:LOC102975790
uniprot id: A0A2Y9FFA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

9755:AMOTL1
gene id: 9755:AMOTL1
uniprot id: A0A2Y9F4W9
uniprot id: A0A2Y9F6J7
names: Similarity
messages: Belongs to the angiomotin family.

9755:LOC102996849
gene id: 9755:LOC102996849
uniprot id: A0A2Y9SGB2
names: Function
names: Subcellular Location Annotation
messages: May function as a transcription factor.
messages: Nucleus

9755:DLG1
gene id: 9755:DLG1
uniprot id: A0A2Y9SWA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: Membrane

9755:POLG2
gene id: 9755:POLG2
uniprot id: A0A2Y9FL17
uniprot id: A0A2Y9FMI8
uniprot id: A0A455CA54
names: Subcellular Location Annotation
messages: Mitochondrion

9755:LOC102988973
gene id: 9755:LOC102988973
uniprot id: A0A455C4R4
uniprot id: A0A455C4R9
uniprot id: A0A455C4S3
uniprot id: A0A455C519
uniprot id: A0A455C525
uniprot id: A0A455C529
uniprot id: A0A455C5U5
uniprot id: A0A455C5V0
uniprot id: A0A455C8L9
uniprot id: A0A455C8M3
uniprot id: A0A455CBH0
uniprot id: A0A455CBH1
uniprot id: A0A455CBH2
names: Caution
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:ERGIC2
gene id: 9755:ERGIC2
uniprot id: A0A2Y9T3V2
uniprot id: A0A2Y9T875
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

9755:MEN1
gene id: 9755:MEN1
uniprot id: A0A2Y9TE37
uniprot id: A0A2Y9TJG4
names: Subcellular Location Annotation
messages: Nucleus

9755:HYLS1
gene id: 9755:HYLS1
uniprot id: A0A2Y9F9N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HYLS1 family.
messages: centriole
messages: cilium

9755:IRX1
gene id: 9755:IRX1
uniprot id: A0A2Y9SWV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

9755:MRPS14
gene id: 9755:MRPS14
uniprot id: A0A2Y9TIM0
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

9755:LOC112065480
gene id: 9755:LOC112065480
uniprot id: A0A455BZ02
uniprot id: A0A455C010
uniprot id: A0A455CA92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

9755:NPTX1
gene id: 9755:NPTX1
uniprot id: A0A2Y9T7I9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:FA2H
gene id: 9755:FA2H
uniprot id: A0A2Y9EIK7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sterol desaturase family. SCS7 subfamily.
messages: Binds 2 Zn(2+) ions per subunit that likely form a catalytic dimetal center.
messages: Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters in sebaceous gland, specifically regulating hair follicle homeostasis. Involved in the synthesis of sphingolipids of plasma membrane rafts, controlling lipid raft mobility and trafficking of raft-associated proteins.
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:LOC112062645
gene id: 9755:LOC112062645
uniprot id: A0A455C7X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 18 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Secreted

9755:ZSCAN9
gene id: 9755:ZSCAN9
uniprot id: A0A455ATL1
names: Subcellular Location Annotation
messages: Nucleus

9755:NETO2
gene id: 9755:NETO2
uniprot id: A0A2Y9SVQ3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:GPHA2
gene id: 9755:GPHA2
uniprot id: A0A2Y9FDN4
names: Caution
names: Function
names: Similarity
messages: Belongs to the glycoprotein hormones subunit alpha family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.

9755:SLC1A1
gene id: 9755:SLC1A1
uniprot id: A0A2Y9FAY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

9755:LOC102995487
gene id: 9755:LOC102995487
uniprot id: A0A2Y9S0Z5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.

9755:MYLK4
gene id: 9755:MYLK4
uniprot id: A0A455ADN3
uniprot id: A0A455AE25
uniprot id: A0A455AG30
names: Similarity
messages: Belongs to the protein kinase superfamily.

9755:CSRNP2
gene id: 9755:CSRNP2
uniprot id: A0A2Y9F2V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

9755:SLC23A2
gene id: 9755:SLC23A2
uniprot id: A0A2Y9SK93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

9755:USP35
gene id: 9755:USP35
uniprot id: A0A2Y9TGZ1
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

9755:LOC102990294
gene id: 9755:LOC102990294
uniprot id: A0A2Y9F1B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

9755:KCNMB2
gene id: 9755:KCNMB2
uniprot id: A0A2Y9EME7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KCNMB (TC 8.A.14.1) family.
messages: Interacts with KCNMA1 tetramer. There are probably 4 molecules of KCMNB per KCNMA1 tetramer.
messages: Membrane
messages: N-glycosylated.
messages: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity.

9755:SMYD2
gene id: 9755:SMYD2
uniprot id: A0A2Y9TIZ3
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically trimethylates histone H3 'Lys-4' (H3K4me3) in vivo. The activity requires interaction with HSP90alpha. Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'.
messages: cytosol

9755:TAGLN
gene id: 9755:TAGLN
uniprot id: A0A2Y9F8H5
names: Similarity
messages: Belongs to the calponin family.

9755:CELSR2
gene id: 9755:CELSR2
uniprot id: A0A455B4W4
names: Subcellular Location Annotation
messages: Membrane

9755:GPR101
gene id: 9755:GPR101
uniprot id: A0A2Y9FGR1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9755:OOEP
gene id: 9755:OOEP
uniprot id: A0A2Y9TJB7
names: Similarity
messages: Belongs to the KHDC1 family.

9755:PLK4
gene id: 9755:PLK4
uniprot id: A0A2Y9FEY9
uniprot id: A0A2Y9FGU0
names: Subcellular Location Annotation
messages: Cleavage furrow
messages: centriole

9755:MRPS12
gene id: 9755:MRPS12
uniprot id: A0A2Y9F4U6
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

9755:SLC39A8
gene id: 9755:SLC39A8
uniprot id: A0A2Y9FD17
uniprot id: A0A2Y9FDF5
names: Subcellular Location Annotation
messages: Membrane

9755:ADGRA3
gene id: 9755:ADGRA3
uniprot id: A0A2Y9F628
uniprot id: A0A2Y9F7T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

9755:GPT
gene id: 9755:GPT
uniprot id: A0A2Y9S427
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

9755:CYSLTR2
gene id: 9755:CYSLTR2
uniprot id: A0A2Y9F6U2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9755:DDX18
gene id: 9755:DDX18
uniprot id: A0A2Y9RWU0
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

9755:GALR1
gene id: 9755:GALR1
uniprot id: A0A2Y9FL43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

9755:LOC102991949
gene id: 9755:LOC102991949
uniprot id: A0A2Y9F2V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

9755:ATP11A
gene id: 9755:ATP11A
uniprot id: A0A2Y9S7B5
uniprot id: A0A455BWV9
uniprot id: A0A455BWW1
uniprot id: A0A455BWW3
uniprot id: A0A455BXM7
uniprot id: A0A455C0H0
uniprot id: A0A455C0H5
uniprot id: A0A455C9R2
uniprot id: A0A455C9R4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:JPH3
gene id: 9755:JPH3
uniprot id: A0A2Y9SY74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

9755:SLC37A3
gene id: 9755:SLC37A3
uniprot id: A0A455B9L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

9755:IFI44L
gene id: 9755:IFI44L
uniprot id: A0A2Y9FF28
names: Similarity
messages: Belongs to the IFI44 family.

9755:PAQR3
gene id: 9755:PAQR3
uniprot id: A0A2Y9RX67
uniprot id: A0A455BGA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

9755:TMEM186
gene id: 9755:TMEM186
uniprot id: A0A2Y9F732
uniprot id: A0A455BZT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM186 family.
messages: Membrane

9755:SLC16A10
gene id: 9755:SLC16A10
uniprot id: A0A2Y9S1J9
names: Subcellular Location Annotation
messages: Membrane

9755:SHQ1
gene id: 9755:SHQ1
uniprot id: A0A2Y9EN41
names: Similarity
messages: Belongs to the SHQ1 family.

9755:PGLYRP2
gene id: 9755:PGLYRP2
uniprot id: A0A2Y9TL35
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

9755:NCR3
gene id: 9755:NCR3
uniprot id: A0A2Y9SFN8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the natural cytotoxicity receptor (NCR) family.
messages: Cell membrane
messages: Homodimer in the unliganted form. Interacts with CD3Z. Interacts with and is activated by binding to NCR3LG1. Interacts with and is activated by binding to BAG6.
messages: Membrane

9755:DDO
gene id: 9755:DDO
uniprot id: A0A2Y9FA53
uniprot id: A0A455BN58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

9755:SGCZ
gene id: 9755:SGCZ
uniprot id: A0A2Y9TGA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

9755:FAT4
gene id: 9755:FAT4
uniprot id: A0A2Y9SFP1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:CMTM3
gene id: 9755:CMTM3
uniprot id: A0A2Y9FKV7
names: Subcellular Location Annotation
messages: Membrane

9755:PRODH2
gene id: 9755:PRODH2
uniprot id: A0A455AE18
names: Function
names: Similarity
messages: Belongs to the proline oxidase family.
messages: Converts proline to delta-1-pyrroline-5-carboxylate.

9755:CNTN2
gene id: 9755:CNTN2
uniprot id: A0A2Y9FXL5
names: Similarity
messages: Belongs to the immunoglobulin superfamily. Contactin family.

9755:IK
gene id: 9755:IK
uniprot id: A0A2Y9ESR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RED family.
messages: Nucleus

9755:LAMTOR5
gene id: 9755:LAMTOR5
uniprot id: A0A2Y9EQV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMTOR5 family.
messages: Lysosome

9755:SNX9
gene id: 9755:SNX9
uniprot id: A0A2Y9SRI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

9755:ARHGEF12
gene id: 9755:ARHGEF12
uniprot id: A0A2Y9FFH6
uniprot id: A0A2Y9FFP8
uniprot id: A0A2Y9FFQ8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane

9755:CDCP2
gene id: 9755:CDCP2
uniprot id: A0A2Y9SAN5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:GPD2
gene id: 9755:GPD2
uniprot id: A0A2Y9FIU4
uniprot id: A0A455ACU8
uniprot id: A0A455AE32
names: Function
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta-cell glucose-sensing device.

9755:NDUFS6
gene id: 9755:NDUFS6
uniprot id: A0A2Y9EN30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS6 subunit family.
messages: Mitochondrion inner membrane

9755:ADH7
gene id: 9755:ADH7
uniprot id: A0A2Y9FDL6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

9755:FOXK1
gene id: 9755:FOXK1
uniprot id: A0A2Y9SJM2
names: Subcellular Location Annotation
messages: Nucleus

9755:AURKAIP1
gene id: 9755:AURKAIP1
uniprot id: A0A2Y9FRH6
uniprot id: A0A455B4E8
names: Similarity
messages: Belongs to the mitochondrion-specific ribosomal protein mS38 family.

9755:MTMR8
gene id: 9755:MTMR8
uniprot id: A0A455APE6
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

9755:ERN2
gene id: 9755:ERN2
uniprot id: A0A2Y9EMY1
uniprot id: A0A2Y9SPH3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:EP300
gene id: 9755:EP300
uniprot id: A0A455BCN8
uniprot id: A0A455BEY0
names: Subcellular Location Annotation
messages: Cytoplasm

9755:C20H10orf53
gene id: 9755:C20H10orf53
uniprot id: A0A2Y9FTY0
names: Similarity
messages: Belongs to the UPF0728 family.

9755:NTRK2
gene id: 9755:NTRK2
uniprot id: A0A455BME8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

9755:REEP1
gene id: 9755:REEP1
uniprot id: A0A455BU41
uniprot id: A0A455BU42
uniprot id: A0A455BUT3
uniprot id: A0A455C8N0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:GJB5
gene id: 9755:GJB5
uniprot id: A0A2Y9SZ53
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9755:CADM2
gene id: 9755:CADM2
uniprot id: A0A455BVA6
names: Similarity
messages: Belongs to the nectin family.

9755:LOC102983937
gene id: 9755:LOC102983937
uniprot id: A0A2Y9T068
names: Subcellular Location Annotation
messages: Membrane

9755:FHIP1A
gene id: 9755:FHIP1A
uniprot id: A0A455BFQ8
uniprot id: A0A455BI34
names: Similarity
messages: Belongs to the FHIP family.

9755:CXXC1
gene id: 9755:CXXC1
uniprot id: A0A2Y9TB35
uniprot id: A0A2Y9TEV6
uniprot id: A0A455AKS3
names: Subcellular Location Annotation
messages: Nucleus

9755:LOC102987211
gene id: 9755:LOC102987211
uniprot id: A0A2Y9S8E0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:TRHDE
gene id: 9755:TRHDE
uniprot id: A0A2Y9SIQ7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Membrane

9755:CCDC153
gene id: 9755:CCDC153
uniprot id: A0A2Y9FIS8
names: Similarity
messages: Belongs to the UPF0610 family.

9755:CYRIB
gene id: 9755:CYRIB
uniprot id: A0A2Y9EHS4
uniprot id: A0A2Y9T8K6
uniprot id: A0A455CB84
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CYRI family.
messages: Interacts with RAC1 (GTP-bound form preferentially).
messages: Membrane

9755:ZNF445
gene id: 9755:ZNF445
uniprot id: A0A2Y9TCH5
names: Subcellular Location Annotation
messages: Nucleus

9755:ESCO1
gene id: 9755:ESCO1
uniprot id: A0A2Y9FNH0
names: Subcellular Location Annotation
messages: Nucleus

9755:KDM1B
gene id: 9755:KDM1B
uniprot id: A0A2Y9SKA8
uniprot id: A0A455AET0
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

9755:SLC25A4
gene id: 9755:SLC25A4
uniprot id: A0A2Y9EY77
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

9755:XCR1
gene id: 9755:XCR1
uniprot id: A0A2Y9FHT3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9755:AP3M2
gene id: 9755:AP3M2
uniprot id: A0A455ALN5
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

9755:MMP28
gene id: 9755:MMP28
uniprot id: A0A2Y9SXQ9
uniprot id: A0A2Y9T1Q7
uniprot id: A0A2Y9T5Q8
uniprot id: A0A455C031
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

9755:LOC102978759
gene id: 9755:LOC102978759
uniprot id: A0A2Y9SPK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

9755:BEX5
gene id: 9755:BEX5
uniprot id: A0A2Y9FHS8
names: Similarity
messages: Belongs to the BEX family.

9755:RPL30
gene id: 9755:RPL30
uniprot id: A0A2Y9EGX2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

9755:PAM
gene id: 9755:PAM
uniprot id: A0A2Y9SDG0
uniprot id: A0A2Y9SE93
uniprot id: A0A2Y9SEA3
uniprot id: A0A2Y9SEA9
uniprot id: A0A2Y9SH85
uniprot id: A0A2Y9SH93
uniprot id: A0A2Y9SHB2
uniprot id: A0A2Y9SK64
uniprot id: A0A2Y9SLX8
uniprot id: A0A455BJA5
uniprot id: A0A455BJJ0
uniprot id: A0A455BM15
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Binds 2 Cu(2+) ions per subunit.
messages: Binds one Zn(2+) ion per subunit.
messages: In the C-terminal section; belongs to the peptidyl-alpha-hydroxyglycine alpha-amidating lyase family.
messages: In the N-terminal section; belongs to the copper type II ascorbate-dependent monooxygenase family.
messages: Membrane
messages: secretory vesicle membrane

9755:SOX4
gene id: 9755:SOX4
uniprot id: A0A2Y9SQ96
names: Subcellular Location Annotation
messages: Nucleus

9755:ULK1
gene id: 9755:ULK1
uniprot id: A0A2Y9SM56
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.
messages: Serine/threonine-protein kinase involved in autophagy in response to starvation.

9755:UBE2K
gene id: 9755:UBE2K
uniprot id: A0A455BHZ9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9755:PLK2
gene id: 9755:PLK2
uniprot id: A0A2Y9EKM7
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

9755:ALLC
gene id: 9755:ALLC
uniprot id: A0A2Y9F6K3
names: Function
names: Similarity
messages: Belongs to the allantoicase family.
messages: The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals.

9755:MAB21L2
gene id: 9755:MAB21L2
uniprot id: A0A2Y9EYQ7
names: Similarity
messages: Belongs to the mab-21 family.

9755:KCNE2
gene id: 9755:KCNE2
uniprot id: A0A455BXA5
names: Similarity
messages: Belongs to the potassium channel KCNE family.

9755:TRIM71
gene id: 9755:TRIM71
uniprot id: A0A2Y9S7S2
names: Similarity
messages: Belongs to the TRIM/RBCC family.

9755:LOC114483883
gene id: 9755:LOC114483883
uniprot id: A0A455C6I3
names: Subcellular Location Annotation
messages: Cytoplasm

9755:ANG
gene id: 9755:ANG
uniprot id: A0A455BQA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

9755:NR6A1
gene id: 9755:NR6A1
uniprot id: A0A2Y9F2F2
uniprot id: A0A2Y9STS2
uniprot id: A0A455BN86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9755:SEPTIN14
gene id: 9755:SEPTIN14
uniprot id: A0A2Y9F5L6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

9755:TASOR2
gene id: 9755:TASOR2
uniprot id: A0A455BNV5
uniprot id: A0A455BNY1
uniprot id: A0A455BPI5
uniprot id: A0A455BS49
uniprot id: A0A455C3Y4
names: Similarity
messages: Belongs to the TASOR family.

9755:PHTF2
gene id: 9755:PHTF2
uniprot id: A0A2Y9S6D1
uniprot id: A0A2Y9S781
uniprot id: A0A455BB04
names: Subcellular Location Annotation
messages: Membrane

9755:DPH5
gene id: 9755:DPH5
uniprot id: A0A2Y9F4U5
uniprot id: A0A455BA81
names: Function
names: Similarity
messages: Belongs to the diphthine synthase family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

9755:DNAJC27
gene id: 9755:DNAJC27
uniprot id: A0A2Y9EG71
uniprot id: A0A2Y9EI61
names: Function
names: Subunit
messages: GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling.
messages: Interacts directly with MAPK1 (wild-type and kinase-deficient forms). Interacts directly (in GTP-bound form) with MAP2K1 (wild-type and kinase-deficient forms).

9755:ADGRG4
gene id: 9755:ADGRG4
uniprot id: A0A455B233
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:LAMA2
gene id: 9755:LAMA2
uniprot id: A0A2Y9SLJ5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

9755:LAMP2
gene id: 9755:LAMP2
uniprot id: A0A2Y9F6M2
uniprot id: A0A2Y9F872
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lysosome membrane
messages: Membrane

9755:PLA2G4E
gene id: 9755:PLA2G4E
uniprot id: A0A2Y9SE47
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

9755:LOC114484525
gene id: 9755:LOC114484525
uniprot id: A0A455AKU8
names: Similarity
messages: Belongs to the hexokinase family.

9755:MRTO4
gene id: 9755:MRTO4
uniprot id: A0A2Y9EL49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the pre-60S ribosomal particle.
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
messages: Cytoplasm
messages: nucleolus

9755:LOC112067303
gene id: 9755:LOC112067303
uniprot id: A0A2Y9TJ00
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:STX6
gene id: 9755:STX6
uniprot id: A0A2Y9EM81
uniprot id: A0A2Y9ENF7
uniprot id: A0A455B662
uniprot id: A0A455B6K6
uniprot id: A0A455B724
uniprot id: A0A455B727
uniprot id: A0A455BKK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Golgi apparatus membrane

9755:PIR
gene id: 9755:PIR
uniprot id: A0A2Y9S5R4
names: Similarity
messages: Belongs to the pirin family.

9755:PKD1
gene id: 9755:PKD1
uniprot id: A0A455C1D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Membrane

9755:CACNB1
gene id: 9755:CACNB1
uniprot id: A0A2Y9F0F7
uniprot id: A0A2Y9F1I9
uniprot id: A0A455BYQ9
uniprot id: A0A455CA74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: Membrane
messages: sarcolemma

9755:TRIO
gene id: 9755:TRIO
uniprot id: A0A455BL57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cytoplasm

9755:SAP18
gene id: 9755:SAP18
uniprot id: A0A2Y9F0C9
names: Similarity
messages: Belongs to the SAP18 family.

9755:ACYP1
gene id: 9755:ACYP1
uniprot id: A0A2Y9FA63
uniprot id: A0A455BSQ6
names: Similarity
messages: Belongs to the acylphosphatase family.

9755:KCTD10
gene id: 9755:KCTD10
uniprot id: A0A2Y9FS66
names: Similarity
messages: Belongs to the BACURD family.

9755:BMP4
gene id: 9755:BMP4
uniprot id: A0A2Y9EIT4
names: Similarity
messages: Belongs to the TGF-beta family.

9755:NKX2-2
gene id: 9755:NKX2-2
uniprot id: A0A2Y9FHD6
names: Subcellular Location Annotation
messages: Nucleus

9755:NPC2
gene id: 9755:NPC2
uniprot id: A0A2Y9F8U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPC2 family.
messages: Secreted

9755:TM9SF4
gene id: 9755:TM9SF4
uniprot id: A0A2Y9FII8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

9755:EXOC6B
gene id: 9755:EXOC6B
uniprot id: A0A2Y9TJP5
uniprot id: A0A2Y9TK74
uniprot id: A0A455BTL9
uniprot id: A0A455BUA6
uniprot id: A0A455BX11
uniprot id: A0A455C8G0
names: Function
names: Similarity
messages: Belongs to the SEC15 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

9755:LOC112062403
gene id: 9755:LOC112062403
uniprot id: A0A2Y9S1K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

9755:CTSL
gene id: 9755:CTSL
uniprot id: A0A455BMI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

9755:CEBPZ
gene id: 9755:CEBPZ
uniprot id: A0A2Y9EKI0
names: Similarity
messages: Belongs to the CBF/MAK21 family.

9755:LOC102981470
gene id: 9755:LOC102981470
uniprot id: A0A455BLE9
uniprot id: A0A455BPE1
names: Subcellular Location Annotation
messages: Nucleus

9755:ZP3
gene id: 9755:ZP3
uniprot id: A0A2Y9EK29
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

9755:TCIRG1
gene id: 9755:TCIRG1
uniprot id: A0A2Y9TE40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

9755:LOC102984531
gene id: 9755:LOC102984531
uniprot id: A0A2Y9SFG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:SPAM1
gene id: 9755:SPAM1
uniprot id: A0A2Y9EEM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 56 family.
messages: Cell membrane
messages: Membrane

9755:RO60
gene id: 9755:RO60
uniprot id: A0A2Y9TEE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

9755:CPSF4L
gene id: 9755:CPSF4L
uniprot id: A0A455BY46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex.
messages: Nucleus

9755:G6PC2
gene id: 9755:G6PC2
uniprot id: A0A2Y9FHR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

9755:LOC102983370
gene id: 9755:LOC102983370
uniprot id: A0A455BDT1
names: Similarity
messages: Belongs to the SKP1 family.

9755:AGPAT1
gene id: 9755:AGPAT1
uniprot id: A0A2Y9FB41
uniprot id: A0A455AH66
uniprot id: A0A455AUU3
names: Domain
names: Function
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

9755:SLC22A3
gene id: 9755:SLC22A3
uniprot id: A0A2Y9SIP5
uniprot id: A0A455BNQ8
uniprot id: A0A455BRY1
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

9755:VRTN
gene id: 9755:VRTN
uniprot id: A0A2Y9F8C9
names: Similarity
messages: Belongs to the vertnin family.

9755:SARAF
gene id: 9755:SARAF
uniprot id: A0A2Y9F9F6
uniprot id: A0A455AZY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SARAF family.
messages: Endoplasmic reticulum membrane
messages: Interacts with STIM1; the interaction is inhibit by th interaction of STIM1 with EFHB.
messages: Membrane
messages: Negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling. In response to cytosolic Ca(2+) elevation after endoplasmic reticulum Ca(2+) refilling, promotes a slow inactivation of STIM (STIM1 or STIM2)-dependent SOCE activity: possibly act by facilitating the deoligomerization of STIM to efficiently turn off ORAI when the endoplasmic reticulum lumen is filled with the appropriate Ca(2+) levels, and thus preventing the overload of the cell with excessive Ca(2+) ions.

9755:WSCD1
gene id: 9755:WSCD1
uniprot id: A0A455BYV1
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9755:PML
gene id: 9755:PML
uniprot id: A0A2Y9EXD6
uniprot id: A0A2Y9EXF3
uniprot id: A0A2Y9EYD8
uniprot id: A0A2Y9EZB7
uniprot id: A0A455BPF7
uniprot id: A0A455BPI0
names: Subcellular Location Annotation
messages: Cytoplasm

9755:SLC39A11
gene id: 9755:SLC39A11
uniprot id: A0A455BY50
names: Subcellular Location Annotation
messages: Membrane

9755:YPEL2
gene id: 9755:YPEL2
uniprot id: A0A2Y9SX92
names: Similarity
messages: Belongs to the yippee family.

9755:MED30
gene id: 9755:MED30
uniprot id: A0A2Y9F193
uniprot id: A0A455C4M2
uniprot id: A0A455C4X5
uniprot id: A0A455CBG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 30 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

9755:ELP2
gene id: 9755:ELP2
uniprot id: A0A2Y9EXJ6
uniprot id: A0A2Y9EY20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ELP2 family.
messages: Cytoplasm
messages: Nucleus

9755:LOC102975070
gene id: 9755:LOC102975070
uniprot id: A0A2Y9F097
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9. Interacts with RNPS1. Interacts with the SRP receptor subunit SRPRA.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). As part of the SRP complex, associates with the SRP receptor (SR) component SRPRA to target secretory proteins to the endoplasmic reticulum membrane. Binds to the signal sequence of presecretory proteins when they emerge from the ribosomes. Displays basal GTPase activity, and stimulates reciprocal GTPase activation of the SR subunit SRPRA. Forms a guanosine 5'-triphosphate (GTP)-dependent complex with the SR subunit SRPRA. SR compaction and GTPase mediated rearrangement of SR drive SRP-mediated cotranslational protein translocation into the ER. Requires the presence of SRP9/SRP14 and/or SRP19 to stably interact with RNA. Plays a role in proliferation and differentiation of granulocytic cells, neutrophils migration capacity and exocrine pancreas development.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Nucleus speckle
messages: The M domain binds the 7SL RNA in presence of SRP19 and binds the signal sequence of presecretory proteins.
messages: The NG domain, also named G domain, is a special guanosine triphosphatase (GTPase) domain, which binds GTP and forms a guanosine 5'-triphosphate (GTP)-dependent complex with a homologous NG domain in the SRP receptor subunit SRPRA. The two NG domains undergo cooperative rearrangements upon their assembly, which culminate in the reciprocal activation of the GTPase activity of one another. SRP receptor compaction upon binding with cargo-loaded SRP and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER.

9755:PICALM
gene id: 9755:PICALM
uniprot id: A0A2Y9FJC2
uniprot id: A0A2Y9FJC4
uniprot id: A0A2Y9FJH6
uniprot id: A0A2Y9FJJ7
uniprot id: A0A2Y9FJK2
uniprot id: A0A2Y9FKD3
uniprot id: A0A2Y9FKD8
uniprot id: A0A2Y9FLJ5
uniprot id: A0A2Y9FLK0
uniprot id: A0A2Y9T8Y2
uniprot id: A0A2Y9TCG2
uniprot id: A0A455C5X1
uniprot id: A0A455C654
uniprot id: A0A455C6X7
uniprot id: A0A455CBQ1
names: Similarity
messages: Belongs to the PICALM/SNAP91 family.

9755:CFAP97D1
gene id: 9755:CFAP97D1
uniprot id: A0A2Y9FR84
names: Similarity
messages: Belongs to the CFAP97 family.

9755:PSMB1
gene id: 9755:PSMB1
uniprot id: A0A2Y9FJB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

9755:ACER2
gene id: 9755:ACER2
uniprot id: A0A2Y9SWI3
uniprot id: A0A2Y9T370
uniprot id: A0A455BLQ0
uniprot id: A0A455BPQ3
uniprot id: A0A455C1H6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:ERI1
gene id: 9755:ERI1
uniprot id: A0A2Y9EG80
uniprot id: A0A2Y9EH51
names: Subcellular Location Annotation
messages: Cytoplasm

9755:SHCBP1L
gene id: 9755:SHCBP1L
uniprot id: A0A2Y9EYL7
names: Subcellular Location Annotation
messages: spindle

9755:SUPT4H1
gene id: 9755:SUPT4H1
uniprot id: A0A2Y9FC48
uniprot id: A0A2Y9FCB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT4 family.
messages: Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II.
messages: Nucleus

9755:PAICS
gene id: 9755:PAICS
uniprot id: A0A2Y9T9W7
uniprot id: A0A2Y9TDP0
names: Similarity
names: Subunit
messages: Homooctamer.
messages: In the C-terminal section; belongs to the AIR carboxylase family. Class II subfamily.
messages: In the N-terminal section; belongs to the SAICAR synthetase family.

9755:LOC102986079
gene id: 9755:LOC102986079
uniprot id: A0A2Y9EZQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Catalyzes the deimination of arginine residues of proteins.
messages: Cytoplasm

9755:RIGI
gene id: 9755:RIGI
uniprot id: A0A455BN35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

9755:VIPAS39
gene id: 9755:VIPAS39
uniprot id: A0A2Y9FF10
uniprot id: A0A2Y9FFA4
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Early endosome
messages: Endosome
messages: Late endosome
messages: Vesicle

9755:KAT2B
gene id: 9755:KAT2B
uniprot id: A0A2Y9S443
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. GCN5 subfamily.
messages: centrosome

9755:SCNN1B
gene id: 9755:SCNN1B
uniprot id: A0A2Y9EPK3
names: Subcellular Location Annotation
messages: Membrane

9755:LOC102994305
gene id: 9755:LOC102994305
uniprot id: A0A2Y9S7D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:PSMD13
gene id: 9755:PSMD13
uniprot id: A0A2Y9TGU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S11 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP). The regulatory particle is made of a lid composed of 9 subunits including PSMD13, a base containing 6 ATPases and few additional components.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

9755:RDH8
gene id: 9755:RDH8
uniprot id: A0A2Y9EL77
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9755:C4H1orf43
gene id: 9755:C4H1orf43
uniprot id: A0A2Y9FVM0
uniprot id: A0A2Y9FWN2
names: Function
names: Subcellular Location Annotation
messages: General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages.
messages: Golgi apparatus
messages: Membrane
messages: Mitochondrion

9755:SCN11A
gene id: 9755:SCN11A
uniprot id: A0A2Y9EYR3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

9755:CFL2
gene id: 9755:CFL2
uniprot id: A0A2Y9SAN2
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

9755:SDHD
gene id: 9755:SDHD
uniprot id: A0A2Y9TFP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CybS family.
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

9755:POT1
gene id: 9755:POT1
uniprot id: A0A2Y9EQN0
uniprot id: A0A2Y9ES84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the telombin family.
messages: Nucleus
messages: telomere

9755:LOC112063969
gene id: 9755:LOC112063969
uniprot id: A0A455BI81
names: Similarity
messages: Belongs to the dopey family.

9755:KCNQ3
gene id: 9755:KCNQ3
uniprot id: A0A455C434
uniprot id: A0A455C4C9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9755:AFF4
gene id: 9755:AFF4
uniprot id: A0A2Y9ENZ9
uniprot id: A0A2Y9EP32
uniprot id: A0A2Y9EQK4
names: Similarity
messages: Belongs to the AF4 family.

9755:GDF6
gene id: 9755:GDF6
uniprot id: A0A2Y9S2N4
names: Similarity
messages: Belongs to the TGF-beta family.

9755:NT5DC2
gene id: 9755:NT5DC2
uniprot id: A0A2Y9SQM9
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

9755:GNPDA1
gene id: 9755:GNPDA1
uniprot id: A0A2Y9EG96
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

9755:GTF2I
gene id: 9755:GTF2I
uniprot id: A0A2Y9SC29
names: Subcellular Location Annotation
messages: Nucleus

9755:PTH1R
gene id: 9755:PTH1R
uniprot id: A0A2Y9FLT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

9755:ATP9A
gene id: 9755:ATP9A
uniprot id: A0A2Y9T5N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

9755:WAS
gene id: 9755:WAS
uniprot id: A0A2Y9F5Z6
names: Subcellular Location Annotation
messages: Nucleus

9755:ANP32B
gene id: 9755:ANP32B
uniprot id: A0A2Y9SZL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANP32 family.
messages: Multifunctional protein that is involved in the regulation of many processes.
messages: Nucleus

9755:WDFY2
gene id: 9755:WDFY2
uniprot id: A0A2Y9ENU8
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

9755:NKX2-3
gene id: 9755:NKX2-3
uniprot id: A0A2Y9SEV8
names: Subcellular Location Annotation
messages: Nucleus

9755:DYNLT3
gene id: 9755:DYNLT3
uniprot id: A0A2Y9S4E1
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

9755:TET2
gene id: 9755:TET2
uniprot id: A0A2Y9EPE9
uniprot id: A0A2Y9EQ13
uniprot id: A0A2Y9ER31
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TET family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Chromosome
messages: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development.
messages: The zinc ions have a structural role.

9755:LOC102995087
gene id: 9755:LOC102995087
uniprot id: A0A2Y9T2T1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

9755:PSIP1
gene id: 9755:PSIP1
uniprot id: A0A2Y9SV88
uniprot id: A0A2Y9SYZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HDGF family.
messages: Nucleus

9755:CHAC1
gene id: 9755:CHAC1
uniprot id: A0A2Y9F0T2
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

9755:TARS1
gene id: 9755:TARS1
uniprot id: A0A2Y9FFC2
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

9755:PPP1R21
gene id: 9755:PPP1R21
uniprot id: A0A2Y9FA64
uniprot id: A0A2Y9FAK0
uniprot id: A0A2Y9FC40
uniprot id: A0A2Y9SE85
uniprot id: A0A455BXP1
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

9755:SMO
gene id: 9755:SMO
uniprot id: A0A2Y9FEM7
uniprot id: A0A455BA59
uniprot id: A0A455BCA4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: cilium

9755:ORC5
gene id: 9755:ORC5
uniprot id: A0A2Y9EZM3
names: Subcellular Location Annotation
messages: Nucleus

9755:TBC1D24
gene id: 9755:TBC1D24
uniprot id: A0A2Y9ECW7
uniprot id: A0A455C1E9
uniprot id: A0A455C5M0
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasmic vesicle membrane
messages: Interacts with ARF6.
messages: Membrane
messages: Presynapse

9755:ACTR6
gene id: 9755:ACTR6
uniprot id: A0A2Y9T4R9
names: Similarity
messages: Belongs to the actin family.

9755:PAN3
gene id: 9755:PAN3
uniprot id: A0A2Y9FM47
uniprot id: A0A2Y9FP46
uniprot id: A0A2Y9SZ01
uniprot id: A0A455BWT4
uniprot id: A0A455BWT6
uniprot id: A0A455BWT8
uniprot id: A0A455BXJ5
uniprot id: A0A455C0E6
uniprot id: A0A455C9Q3
uniprot id: A0A455C9Q5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. PAN3 family.
messages: Contains a pseudokinase domain. The protein kinase domain is predicted to be catalytically inactive because some of the residues important for catalytic activity are substituted and it lacks the equivalent of the binding site for a peptide substrate. However, it has retained an ATP-binding site and ATP-binding is required for mRNA degradation, stimulating the activity of the PAN2 nuclease in vitro. The nucleotide-binding site is juxtaposed to the RNase active site of PAN2 in the complex and may actually bind nucleosides of a poly(A) RNA rather than ATP, feeding the poly(A)-tail to the active site of the deadenylase and thus increasing the efficiency with which this distributive enzyme degrades oligo(A) RNAs.
messages: Homodimer. Forms a heterotrimer with a catalytic subunit PAN2 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts (via PAM-2 motif) with poly(A)-binding protein PABPC1 (via PABC domain), conferring substrate specificity of the enzyme complex. Interacts with the GW182 family proteins TNRC6A, TNRC6B and TNRC6C.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: P-body
messages: Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and PABP, and to miRNA targets via its interaction with GW182 family proteins.
messages: The N-terminal zinc finger binds to poly(A) RNA.
messages: The pseudokinase domain, the coiled-coil (CC), and C-terminal knob domain (CK) form a structural unit (PKC) that forms an extensive high-affinity interaction surface for PAN2.

9755:PMPCA
gene id: 9755:PMPCA
uniprot id: A0A2Y9STU4
uniprot id: A0A455BWH9
names: Similarity
messages: Belongs to the peptidase M16 family.

9755:NTMT2
gene id: 9755:NTMT2
uniprot id: A0A2Y9F7N4
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

9755:TNMD
gene id: 9755:TNMD
uniprot id: A0A2Y9EVX1
names: Similarity
messages: Belongs to the chondromodulin-1 family.

9755:AHSA1
gene id: 9755:AHSA1
uniprot id: A0A2Y9FFA9
uniprot id: A0A2Y9S9T0
names: Similarity
messages: Belongs to the AHA1 family.

9755:ZAR1L
gene id: 9755:ZAR1L
uniprot id: A0A2Y9EPA1
uniprot id: A0A455BXH7
uniprot id: A0A455C9Y1
names: Similarity
names: Subunit
messages: Belongs to the ZAR1 family.
messages: Interacts with YBX2.

9755:ADAMTS1
gene id: 9755:ADAMTS1
uniprot id: A0A2Y9FIT3
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9755:SH3RF3
gene id: 9755:SH3RF3
uniprot id: A0A2Y9S994
names: Similarity
messages: Belongs to the SH3RF family.

9755:COQ2
gene id: 9755:COQ2
uniprot id: A0A2Y9S177
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
messages: Mitochondrion inner membrane

9755:SEC61A1
gene id: 9755:SEC61A1
uniprot id: A0A2Y9FWQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecY/SEC61-alpha family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:LOC114484210
gene id: 9755:LOC114484210
uniprot id: A0A455AE35
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

9755:PRPF18
gene id: 9755:PRPF18
uniprot id: A0A2Y9FLA5
uniprot id: A0A455BTZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP18 family.
messages: Nucleus speckle

9755:ABCC6
gene id: 9755:ABCC6
uniprot id: A0A2Y9FPN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

9755:SLC10A1
gene id: 9755:SLC10A1
uniprot id: A0A2Y9F1W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

9755:MMP23B
gene id: 9755:MMP23B
uniprot id: A0A2Y9SSS8
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:MAP3K5
gene id: 9755:MAP3K5
uniprot id: A0A2Y9SIX6
uniprot id: A0A455BMS0
uniprot id: A0A455C2P7
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

9755:CCNT1
gene id: 9755:CCNT1
uniprot id: A0A2Y9ER92
uniprot id: A0A2Y9SQU7
names: Similarity
messages: Belongs to the cyclin family.

9755:PARD6B
gene id: 9755:PARD6B
uniprot id: A0A2Y9FRD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

9755:CILP
gene id: 9755:CILP
uniprot id: A0A2Y9T776
uniprot id: A0A455BV38
names: Subcellular Location Annotation
messages: extracellular matrix

9755:GATA1
gene id: 9755:GATA1
uniprot id: A0A2Y9FIZ4
uniprot id: A0A2Y9S257
names: Subcellular Location Annotation
messages: Nucleus

9755:SPNS2
gene id: 9755:SPNS2
uniprot id: A0A2Y9T666
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

9755:TNKS
gene id: 9755:TNKS
uniprot id: A0A2Y9TAM5
names: Function
names: Similarity
messages: Belongs to the ARTD/PARP family.
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

9755:B4GALT5
gene id: 9755:B4GALT5
uniprot id: A0A2Y9T5K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

9755:TPRG1L
gene id: 9755:TPRG1L
uniprot id: A0A2Y9SXN9
uniprot id: A0A2Y9SZR5
names: Similarity
messages: Belongs to the TPRG1 family.

9755:CLGN
gene id: 9755:CLGN
uniprot id: A0A2Y9FF90
uniprot id: A0A455BFE8
uniprot id: A0A455BHX6
names: Similarity
messages: Belongs to the calreticulin family.

9755:PTPN2
gene id: 9755:PTPN2
uniprot id: A0A2Y9SC93
uniprot id: A0A2Y9SG75
uniprot id: A0A2Y9SJ10
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

9755:LOC102977760
gene id: 9755:LOC102977760
uniprot id: A0A2Y9T7P3
names: Similarity
messages: Belongs to the NXPE family.

9755:VPS35L
gene id: 9755:VPS35L
uniprot id: A0A455BXT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS35L family.
messages: Endosome

9755:DNASE2B
gene id: 9755:DNASE2B
uniprot id: A0A2Y9S9H3
names: Similarity
messages: Belongs to the DNase II family.

9755:LOC114487450
gene id: 9755:LOC114487450
uniprot id: A0A455BVZ9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:VPS26B
gene id: 9755:VPS26B
uniprot id: A0A2Y9T7Q4
names: Similarity
messages: Belongs to the VPS26 family.

9755:CDO1
gene id: 9755:CDO1
uniprot id: A0A2Y9FAC8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cysteine dioxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the oxidation of cysteine to cysteine sulfinic acid with addition of molecular dioxygen.

9755:NUTM1
gene id: 9755:NUTM1
uniprot id: A0A2Y9FNV5
names: Similarity
messages: Belongs to the NUT family.

9755:WAPL
gene id: 9755:WAPL
uniprot id: A0A2Y9FG15
uniprot id: A0A2Y9FGD5
names: Similarity
messages: Belongs to the WAPL family.

9755:RSPO4
gene id: 9755:RSPO4
uniprot id: A0A2Y9T207
names: Similarity
messages: Belongs to the R-spondin family.

9755:WTAP
gene id: 9755:WTAP
uniprot id: A0A2Y9SR85
uniprot id: A0A455BPC2
names: Similarity
messages: Belongs to the fl(2)d family.

9755:CTLA4
gene id: 9755:CTLA4
uniprot id: A0A2Y9FBH0
uniprot id: A0A2Y9FBQ4
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
messages: Membrane

9755:SEC62
gene id: 9755:SEC62
uniprot id: A0A455BG25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC62 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:KMT5A
gene id: 9755:KMT5A
uniprot id: A0A2Y9SE29
uniprot id: A0A2Y9SH29
uniprot id: A0A2Y9SJY8
uniprot id: A0A455AI03
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

9755:GRK1
gene id: 9755:GRK1
uniprot id: A0A2Y9F8A5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

9755:SRC
gene id: 9755:SRC
uniprot id: A0A455BZU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

9755:MTERF3
gene id: 9755:MTERF3
uniprot id: A0A2Y9EXT5
names: Similarity
messages: Belongs to the mTERF family.

9755:CDC42EP3
gene id: 9755:CDC42EP3
uniprot id: A0A2Y9FHR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

9755:CCND2
gene id: 9755:CCND2
uniprot id: A0A2Y9F9Z9
names: Similarity
messages: Belongs to the cyclin family.

9755:KMT5B
gene id: 9755:KMT5B
uniprot id: A0A2Y9TFE3
uniprot id: A0A455C652
uniprot id: A0A455C755
uniprot id: A0A455CBR6
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

9755:SNU13
gene id: 9755:SNU13
uniprot id: A0A2Y9T313
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

9755:AREG
gene id: 9755:AREG
uniprot id: A0A2Y9FH20
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:RGS2
gene id: 9755:RGS2
uniprot id: A0A2Y9T6G2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: nucleolus

9755:PPP6C
gene id: 9755:PPP6C
uniprot id: A0A2Y9F9B8
uniprot id: A0A455BKD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family.
messages: Cytoplasm

9755:LOC102976852
gene id: 9755:LOC102976852
uniprot id: A0A2Y9SEC6
names: Similarity
messages: Belongs to the calreticulin family.

9755:TRIM32
gene id: 9755:TRIM32
uniprot id: A0A2Y9FPV6
names: Similarity
messages: Belongs to the TRIM/RBCC family.

9755:HINT1
gene id: 9755:HINT1
uniprot id: A0A2Y9FIA6
names: Similarity
messages: Belongs to the HINT family.

9755:STK11
gene id: 9755:STK11
uniprot id: A0A2Y9FTB2
uniprot id: A0A455C6M8
uniprot id: A0A455C8Z4
uniprot id: A0A455CBN3
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. LKB1 subfamily.

9755:IMPDH1
gene id: 9755:IMPDH1
uniprot id: A0A2Y9T6Y1
uniprot id: A0A2Y9TCZ5
uniprot id: A0A2Y9TEY7
uniprot id: A0A455B9E2
uniprot id: A0A455B9X3
uniprot id: A0A455BNY5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.
messages: Nucleus

9755:LOC102989310
gene id: 9755:LOC102989310
uniprot id: A0A2Y9T0E3
names: Similarity
messages: Belongs to the cytochrome P450 family.

9755:ST8SIA1
gene id: 9755:ST8SIA1
uniprot id: A0A2Y9T450
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9755:LRP12
gene id: 9755:LRP12
uniprot id: A0A2Y9T5K7
uniprot id: A0A2Y9T7L1
uniprot id: A0A2Y9TC36
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:CNIH1
gene id: 9755:CNIH1
uniprot id: A0A2Y9EGW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

9755:IFNK
gene id: 9755:IFNK
uniprot id: A0A2Y9F457
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

9755:TBC1D7
gene id: 9755:TBC1D7
uniprot id: A0A2Y9SM80
uniprot id: A0A455AHK7
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Vesicle

9755:IKBKE
gene id: 9755:IKBKE
uniprot id: A0A455B5W0
uniprot id: A0A455B695
uniprot id: A0A455B6S5
uniprot id: A0A455B6S9
uniprot id: A0A455B8L6
uniprot id: A0A455BKA0
names: Subcellular Location Annotation
messages: Cytoplasm

9755:LCA5L
gene id: 9755:LCA5L
uniprot id: A0A455BI40
names: Similarity
messages: Belongs to the LCA5 family.

9755:LRP6
gene id: 9755:LRP6
uniprot id: A0A2Y9T543
uniprot id: A0A455BCW5
uniprot id: A0A455BDK8
uniprot id: A0A455BFX9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDLR family.
messages: Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalosomes.
messages: Homodimer; disulfide-linked. Forms phosphorylated oligomer aggregates on Wnt-signaling.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:HHIPL1
gene id: 9755:HHIPL1
uniprot id: A0A2Y9T9A0
names: Caution
names: Similarity
messages: Belongs to the HHIP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:NT5C3A
gene id: 9755:NT5C3A
uniprot id: A0A2Y9F1A9
uniprot id: A0A2Y9F2G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

9755:MSX1
gene id: 9755:MSX1
uniprot id: A0A2Y9SGP2
names: Subcellular Location Annotation
messages: Nucleus

9755:PSMD11
gene id: 9755:PSMD11
uniprot id: A0A2Y9ER04
names: Similarity
messages: Belongs to the proteasome subunit S9 family.

9755:OCRL
gene id: 9755:OCRL
uniprot id: A0A2Y9SYY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: phagosome membrane

9755:GHRH
gene id: 9755:GHRH
uniprot id: A0A2Y9EKY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

9755:LOC112063836
gene id: 9755:LOC112063836
uniprot id: A0A2Y9SGF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase e subunit family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

9755:MLNR
gene id: 9755:MLNR
uniprot id: A0A2Y9EMG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9755:ROR2
gene id: 9755:ROR2
uniprot id: A0A2Y9EVD5
uniprot id: A0A2Y9T8A2
uniprot id: A0A2Y9T9X7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:LPIN2
gene id: 9755:LPIN2
uniprot id: A0A2Y9SCE8
uniprot id: A0A2Y9SJ62
uniprot id: A0A455AHI9
uniprot id: A0A455AI09
uniprot id: A0A455AJG9
uniprot id: A0A455AJN3
uniprot id: A0A455AVW0
names: Similarity
messages: Belongs to the lipin family.

9755:SELL
gene id: 9755:SELL
uniprot id: A0A2Y9EGW0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the selectin/LECAM family.
messages: Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia.
messages: Cell membrane
messages: Interaction with SELPLG/PSGL1 and PODXL2 is required for promoting recruitment and rolling of leukocytes. This interaction is dependent on the sialyl Lewis X glycan modification of SELPLG and PODXL2, and tyrosine sulfation modifications of SELPLG. Sulfation on 'Tyr-51' of SELPLG is important for L-selectin binding.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:SLC16A11
gene id: 9755:SLC16A11
uniprot id: A0A2Y9T015
names: Subcellular Location Annotation
messages: Membrane

9755:SEMA6C
gene id: 9755:SEMA6C
uniprot id: A0A2Y9FTT8
uniprot id: A0A2Y9FTU8
uniprot id: A0A455B6S6
uniprot id: A0A455B7M7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:RPGRIP1L
gene id: 9755:RPGRIP1L
uniprot id: A0A2Y9EWG8
uniprot id: A0A455ACS0
uniprot id: A0A455ANF6
names: Similarity
messages: Belongs to the RPGRIP1 family.

9755:MDGA2
gene id: 9755:MDGA2
uniprot id: A0A2Y9SCR2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9755:ADGRF5
gene id: 9755:ADGRF5
uniprot id: A0A455AEX8
uniprot id: A0A455ASC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

9755:IDS
gene id: 9755:IDS
uniprot id: A0A455APJ8
names: Similarity
messages: Belongs to the sulfatase family.

9755:CDS2
gene id: 9755:CDS2
uniprot id: A0A2Y9F504
uniprot id: A0A455C0Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Membrane

9755:TASOR
gene id: 9755:TASOR
uniprot id: A0A2Y9SLZ2
uniprot id: A0A2Y9SMS1
uniprot id: A0A2Y9ST67
uniprot id: A0A2Y9SV51
uniprot id: A0A455AF58
uniprot id: A0A455AHI5
uniprot id: A0A455AT45
names: Similarity
messages: Belongs to the TASOR family.

9755:CDKN1A
gene id: 9755:CDKN1A
uniprot id: A0A2Y9ENU9
names: Similarity
messages: Belongs to the CDI family.

9755:TRPM5
gene id: 9755:TRPM5
uniprot id: A0A2Y9TE99
names: Subcellular Location Annotation
messages: Membrane

9755:NMT1
gene id: 9755:NMT1
uniprot id: A0A2Y9TCN9
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

9755:MTR
gene id: 9755:MTR
uniprot id: A0A2Y9RYB9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methylcob(III)alamin (MeCbl) to homocysteine, yielding enzyme-bound cob(I)alamin and methionine in the cytosol. MeCbl is an active form of cobalamin (vitamin B12) used as a cofactor for methionine biosynthesis. Cob(I)alamin form is regenerated to MeCbl by a transfer of a methyl group from 5-methyltetrahydrofolate. The processing of cobalamin in the cytosol occurs in a multiprotein complex composed of at least MMACHC, MMADHC, MTRR (methionine synthase reductase) and MTR which may contribute to shuttle safely and efficiently cobalamin towards MTR in order to produce methionine.
messages: Cytoplasm
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

9755:FOXL1
gene id: 9755:FOXL1
uniprot id: A0A2Y9EWE6
names: Subcellular Location Annotation
messages: Nucleus

9755:CYGB
gene id: 9755:CYGB
uniprot id: A0A2Y9TB15
names: Similarity
messages: Belongs to the globin family.

9755:CTSC
gene id: 9755:CTSC
uniprot id: A0A2Y9TFA8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C1 family.
messages: Lysosome
messages: Tetramer of heterotrimers consisting of exclusion domain, heavy- and light chains.

9755:SRSF1
gene id: 9755:SRSF1
uniprot id: A0A455BZB2
names: Similarity
messages: Belongs to the splicing factor SR family.

9755:ODAM
gene id: 9755:ODAM
uniprot id: A0A2Y9FBL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ODAM family.
messages: Cytoplasm
messages: Interacts (via C-terminus) with ARHGEF5.
messages: Nucleus
messages: Secreted
messages: Tooth-associated epithelia protein that probably plays a role in odontogenesis, the complex process that results in the initiation and generation of the tooth. May be incorporated in the enamel matrix at the end of mineralization process. Involved in the induction of RHOA activity via interaction with ARHGEF and expression of downstream factors such as ROCK. Plays a role in attachment of the junctional epithelium to the tooth surface.

9755:DOP1A
gene id: 9755:DOP1A
uniprot id: A0A455BTC9
names: Similarity
messages: Belongs to the dopey family.

9755:PHC3
gene id: 9755:PHC3
uniprot id: A0A2Y9SNB6
uniprot id: A0A2Y9SPA4
uniprot id: A0A2Y9SRS8
uniprot id: A0A2Y9SRT0
uniprot id: A0A2Y9SWJ3
uniprot id: A0A455BSR1
uniprot id: A0A455BSS5
names: Subcellular Location Annotation
messages: Nucleus

9755:VWC2
gene id: 9755:VWC2
uniprot id: A0A2Y9RX58
names: Subcellular Location Annotation
messages: Synapse

9755:GRK6
gene id: 9755:GRK6
uniprot id: A0A2Y9S0F2
uniprot id: A0A2Y9S7F1
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

9755:TFB2M
gene id: 9755:TFB2M
uniprot id: A0A2Y9FF17
uniprot id: A0A2Y9FF65
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:GABRP
gene id: 9755:GABRP
uniprot id: A0A2Y9S6U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9755:NSG2
gene id: 9755:NSG2
uniprot id: A0A2Y9ES83
names: Similarity
messages: Belongs to the NSG family.

9755:EIF4H
gene id: 9755:EIF4H
uniprot id: A0A455BYP3
names: Function
names: Subcellular Location Annotation
messages: Stimulates the RNA helicase activity of EIF4A in the translation initiation complex. Binds weakly mRNA.
messages: perinuclear region

9755:TYR
gene id: 9755:TYR
uniprot id: A0A2Y9EY06
uniprot id: A0A2Y9EY31
uniprot id: A0A2Y9F036
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

9755:GCFC2
gene id: 9755:GCFC2
uniprot id: A0A2Y9FBT6
uniprot id: A0A2Y9FC11
uniprot id: A0A2Y9FC82
uniprot id: A0A2Y9FDS7
uniprot id: A0A455BXY7
uniprot id: A0A455C8T6
names: Similarity
messages: Belongs to the GCF family.

9755:RPLP2
gene id: 9755:RPLP2
uniprot id: A0A2Y9EU66
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

9755:TMEM120B
gene id: 9755:TMEM120B
uniprot id: A0A2Y9FQX8
uniprot id: A0A2Y9FR32
uniprot id: A0A455AVT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM120 family.
messages: Membrane
messages: Nucleus inner membrane

9755:GIP
gene id: 9755:GIP
uniprot id: A0A2Y9EUV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion.
messages: Secreted

9755:INTU
gene id: 9755:INTU
uniprot id: A0A2Y9F1Q0
uniprot id: A0A2Y9F1Y7
uniprot id: A0A2Y9F280
uniprot id: A0A2Y9F342
uniprot id: A0A2Y9F3M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inturned family.
messages: Cell surface
messages: cilium basal body

9755:LCNL1
gene id: 9755:LCNL1
uniprot id: A0A2Y9FPY9
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

9755:MRPL11
gene id: 9755:MRPL11
uniprot id: A0A2Y9FPZ4
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

9755:MEIS1
gene id: 9755:MEIS1
uniprot id: A0A455BUI5
uniprot id: A0A455BUI7
uniprot id: A0A455C8U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

9755:LOC102982618
gene id: 9755:LOC102982618
uniprot id: A0A2Y9SE45
names: Similarity
messages: Belongs to the cytochrome P450 family.

9755:SUMF2
gene id: 9755:SUMF2
uniprot id: A0A2Y9EPU0
uniprot id: A0A2Y9EPX1
uniprot id: A0A2Y9EQE4
uniprot id: A0A2Y9ER91
uniprot id: A0A2Y9ERE5
uniprot id: A0A455BZQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase-modifying factor family.
messages: Endoplasmic reticulum lumen

9755:LOC102987686
gene id: 9755:LOC102987686
uniprot id: A0A2Y9EWX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Mitochondrion intermembrane space
messages: Required for assembly of mitochondrial respiratory chain complexes.

9755:TRPC6
gene id: 9755:TRPC6
uniprot id: A0A2Y9RX19
uniprot id: A0A2Y9S0U4
uniprot id: A0A2Y9S5B5
names: Subcellular Location Annotation
messages: Membrane

9755:RPL7L1
gene id: 9755:RPL7L1
uniprot id: A0A2Y9SQ52
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

9755:HAPSTR2
gene id: 9755:HAPSTR2
uniprot id: A0A2Y9F9S5
names: Subcellular Location Annotation
messages: Nucleus

9755:ESD
gene id: 9755:ESD
uniprot id: A0A2Y9EIV5
uniprot id: A0A2Y9EJ10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the esterase D family.
messages: Cytoplasmic vesicle
messages: Serine hydrolase involved in the detoxification of formaldehyde.

9755:TMPRSS2
gene id: 9755:TMPRSS2
uniprot id: A0A2Y9SCJ6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:MPEG1
gene id: 9755:MPEG1
uniprot id: A0A2Y9FDD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPEG1 family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

9755:PHC1
gene id: 9755:PHC1
uniprot id: A0A2Y9T5C5
uniprot id: A0A2Y9T9W9
uniprot id: A0A455BCU0
uniprot id: A0A455BSF1
names: Subcellular Location Annotation
messages: Nucleus

9755:RAB27A
gene id: 9755:RAB27A
uniprot id: A0A2Y9T154
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

9755:HOXC10
gene id: 9755:HOXC10
uniprot id: A0A2Y9FKN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

9755:ALDH1L1
gene id: 9755:ALDH1L1
uniprot id: A0A455AET8
uniprot id: A0A455AG52
uniprot id: A0A455AS80
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
messages: In the N-terminal section; belongs to the GART family.

9755:RNPC3
gene id: 9755:RNPC3
uniprot id: A0A455B883
uniprot id: A0A455BA60
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the U11/U12 snRNPs that are part of the U12-type spliceosome. Found in a complex with m(7)G-capped U12 snRNA. Interacts with PDCD7.
messages: Nucleus
messages: Participates in pre-mRNA U12-dependent splicing, performed by the minor spliceosome which removes U12-type introns. U12-type introns comprises less than 1% of all non-coding sequences. Binds to the 3'-stem-loop of m(7)G-capped U12 snRNA.

9755:SBDS
gene id: 9755:SBDS
uniprot id: A0A2Y9F7X4
names: Function
names: Similarity
messages: Belongs to the SDO1/SBDS family.
messages: Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.

9755:MINDY4B
gene id: 9755:MINDY4B
uniprot id: A0A455BD35
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
messages: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

9755:XPO7
gene id: 9755:XPO7
uniprot id: A0A2Y9T8B9
uniprot id: A0A2Y9T9Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus

9755:NOC3L
gene id: 9755:NOC3L
uniprot id: A0A2Y9FNC0
uniprot id: A0A2Y9FNM5
uniprot id: A0A2Y9FQQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF/MAK21 family.
messages: nucleolus

9755:MDM2
gene id: 9755:MDM2
uniprot id: A0A2Y9FGP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Cytoplasm
messages: nucleolus
messages: nucleoplasm

9755:HACD1
gene id: 9755:HACD1
uniprot id: A0A455BTD7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:PIGG
gene id: 9755:PIGG
uniprot id: A0A2Y9F325
uniprot id: A0A2Y9F339
uniprot id: A0A2Y9F3B5
uniprot id: A0A2Y9F449
uniprot id: A0A2Y9F4W6
uniprot id: A0A455BHI5
uniprot id: A0A455BK58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGG subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:WARS1
gene id: 9755:WARS1
uniprot id: A0A455BT71
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9755:SNRPD1
gene id: 9755:SNRPD1
uniprot id: A0A2Y9FQV6
uniprot id: A0A2Y9SCJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP core protein family.
messages: Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Most spliceosomal snRNPs contain a common set of Sm proteins, SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. Component of the U1 snRNP. The U1 snRNP is composed of the U1 snRNA and the 7 core Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG, and at least three U1 snRNP-specific proteins SNRNP70/U1-70K, SNRPA/U1-A and SNRPC/U1-C. Component of the U4/U6-U5 tri-snRNP complex composed of the U4, U6 and U5 snRNAs and at least PRPF3, PRPF4, PRPF6, PRPF8, PRPF31, SNRNP200, TXNL4A, SNRNP40, SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF, SNRPG, DDX23, CD2BP2, PPIH, SNU13, EFTUD2, SART1 and USP39, plus LSM2, LSM3, LSM4, LSM5, LSM6, LSM7 and LSM8. Component of the minor spliceosome, which splices U12-type introns. Part of the SMN-Sm complex that contains SMN1, GEMIN2/SIP1, DDX20/GEMIN3, GEMIN4, GEMIN5, GEMIN6, GEMIN7, GEMIN8, STRAP/UNRIP and the Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG; catalyzes core snRNPs assembly. Forms a 6S pICln-Sm complex composed of CLNS1A/pICln, SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG; ring-like structure where CLNS1A/pICln mimics additional Sm proteins and which is unable to assemble into the core snRNP. Interacts (via C-terminus) with SMN1 (via Tudor domain); the interaction is direct. Interacts with GEMIN2; the interaction is direct. Interacts with SNRPD2; the interaction is direct.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA.
messages: cytosol

9755:SLC29A3
gene id: 9755:SLC29A3
uniprot id: A0A2Y9EYT1
uniprot id: A0A2Y9F0A4
uniprot id: A0A455ALV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

9755:MESD
gene id: 9755:MESD
uniprot id: A0A2Y9FLU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MESD family.
messages: Endoplasmic reticulum

9755:TFAP2C
gene id: 9755:TFAP2C
uniprot id: A0A2Y9T1U4
names: Similarity
messages: Belongs to the AP-2 family.

9755:SPX
gene id: 9755:SPX
uniprot id: A0A2Y9T3R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spexin family.
messages: Secreted

9755:SLC39A9
gene id: 9755:SLC39A9
uniprot id: A0A2Y9F992
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Cell membrane
messages: Membrane
messages: Mitochondrion
messages: Nucleus
messages: Transports zinc ions across cell and organelle membranes into the cytoplasm and regulates intracellular zinc homeostasis. Participates in the zinc ions efflux out of the secretory compartments. Also functions as membrane androgen receptor that mediates, through a G protein, the non-classical androgen signaling pathway, characterized by the activation of MAPK3/MAPK1 (Erk1/2) and transcription factors CREB1 or ATF1. Moreover, has dual functions as membrane-bound androgen receptor and as an androgen-dependent zinc transporter both of which are mediated through an inhibitory G protein (Gi) that mediates both MAP kinase and zinc signaling leading to the androgen-dependent apoptotic process.
messages: perinuclear region
messages: trans-Golgi network membrane

9755:ANO4
gene id: 9755:ANO4
uniprot id: A0A2Y9SWJ6
uniprot id: A0A2Y9SXX8
uniprot id: A0A2Y9SXY3
uniprot id: A0A2Y9T0I6
uniprot id: A0A2Y9T2G0
uniprot id: A0A2Y9T4L4
uniprot id: A0A2Y9T4M1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:MARCHF11
gene id: 9755:MARCHF11
uniprot id: A0A2Y9T0I7
names: Subcellular Location Annotation
messages: Membrane

9755:TMEM254
gene id: 9755:TMEM254
uniprot id: A0A2Y9TAH7
names: Subcellular Location Annotation
messages: Membrane

9755:BNIP1
gene id: 9755:BNIP1
uniprot id: A0A2Y9FR66
names: Subcellular Location Annotation
messages: Membrane

9755:CDK7
gene id: 9755:CDK7
uniprot id: A0A2Y9FSY3
uniprot id: A0A2Y9SKN9
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

9755:FAM98B
gene id: 9755:FAM98B
uniprot id: A0A2Y9EZ11
names: Similarity
messages: Belongs to the FAM98 family.

9755:ACADSB
gene id: 9755:ACADSB
uniprot id: A0A2Y9SF61
uniprot id: A0A2Y9SI05
uniprot id: A0A455B1I2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

9755:IRX4
gene id: 9755:IRX4
uniprot id: A0A2Y9SKI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

9755:KIN
gene id: 9755:KIN
uniprot id: A0A2Y9FDQ6
uniprot id: A0A455BP20
names: Similarity
messages: Belongs to the KIN17 family.

9755:RC3H1
gene id: 9755:RC3H1
uniprot id: A0A2Y9TGQ8
uniprot id: A0A2Y9TKA8
uniprot id: A0A455B6Z9
names: Subcellular Location Annotation
messages: P-body

9755:GPR6
gene id: 9755:GPR6
uniprot id: A0A2Y9ELE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9755:LOC102976645
gene id: 9755:LOC102976645
uniprot id: A0A2Y9RZC0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:SLC22A18
gene id: 9755:SLC22A18
uniprot id: A0A2Y9FKV3
names: Subcellular Location Annotation
messages: Membrane

9755:LOC112066581
gene id: 9755:LOC112066581
uniprot id: A0A455BYX7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

9755:LOC102983710
gene id: 9755:LOC102983710
uniprot id: A0A2Y9T0X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

9755:UTRN
gene id: 9755:UTRN
uniprot id: A0A2Y9SIL5
uniprot id: A0A2Y9SJ64
uniprot id: A0A2Y9SM04
uniprot id: A0A2Y9SM09
uniprot id: A0A2Y9SQ08
names: Subcellular Location Annotation
messages: cytoskeleton

9755:SNTG2
gene id: 9755:SNTG2
uniprot id: A0A455BUG4
uniprot id: A0A455BUG5
uniprot id: A0A455BUG9
uniprot id: A0A455BUH0
uniprot id: A0A455BUH4
uniprot id: A0A455BUH5
uniprot id: A0A455BV46
uniprot id: A0A455BV50
uniprot id: A0A455BV55
uniprot id: A0A455BXX4
uniprot id: A0A455BXX9
uniprot id: A0A455BXY4
uniprot id: A0A455C8T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: cytoskeleton

9755:IRAK4
gene id: 9755:IRAK4
uniprot id: A0A2Y9EQ34
uniprot id: A0A2Y9EQJ3
uniprot id: A0A2Y9ERL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with MYD88 and IRAK2 to form a ternary complex called the Myddosome.
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
messages: Cytoplasm
messages: Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens.

9755:NDUFB11
gene id: 9755:NDUFB11
uniprot id: A0A2Y9ELV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB11 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane

9755:NCOA3
gene id: 9755:NCOA3
uniprot id: A0A2Y9SZJ8
uniprot id: A0A2Y9T7K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.
messages: Nucleus

9755:LOC112064292
gene id: 9755:LOC112064292
uniprot id: A0A2Y9SM47
names: Similarity
messages: Belongs to the MHC class I family.

9755:LOC112062150
gene id: 9755:LOC112062150
uniprot id: A0A2Y9RYH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

9755:ACE
gene id: 9755:ACE
uniprot id: A0A455C1X7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M2 family.
messages: Binds 2 Zn(2+) ions per subunit.

9755:CPSF3
gene id: 9755:CPSF3
uniprot id: A0A2Y9S7M6
uniprot id: A0A2Y9SFF7
names: Subcellular Location Annotation
messages: Nucleus

9755:TSHZ3
gene id: 9755:TSHZ3
uniprot id: A0A2Y9TDD5
uniprot id: A0A2Y9TIQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.
messages: Nucleus

9755:CRLS1
gene id: 9755:CRLS1
uniprot id: A0A2Y9SLB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

9755:SS18
gene id: 9755:SS18
uniprot id: A0A2Y9FA69
uniprot id: A0A2Y9FAA4
uniprot id: A0A2Y9FAK3
uniprot id: A0A2Y9FC45
uniprot id: A0A455AVP8
names: Similarity
messages: Belongs to the SS18 family.

9755:NGF
gene id: 9755:NGF
uniprot id: A0A2Y9EJ77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Secreted

9755:LOC102985868
gene id: 9755:LOC102985868
uniprot id: A0A2Y9T577
names: Similarity
messages: Belongs to the cytochrome P450 family.

9755:LOC114486512
gene id: 9755:LOC114486512
uniprot id: A0A455BEY2
names: Subcellular Location Annotation
messages: Membrane

9755:RSBN1
gene id: 9755:RSBN1
uniprot id: A0A2Y9SE20
uniprot id: A0A455BLM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the round spermatid basic protein 1 family.
messages: Nucleus

9755:MYO3B
gene id: 9755:MYO3B
uniprot id: A0A2Y9SQN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: In the C-terminal section; belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: cytoskeleton

9755:LRP3
gene id: 9755:LRP3
uniprot id: A0A2Y9THT7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:ME2
gene id: 9755:ME2
uniprot id: A0A2Y9EL21
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

9755:EML6
gene id: 9755:EML6
uniprot id: A0A2Y9SDF6
uniprot id: A0A2Y9SEU9
names: Function
names: Similarity
messages: Belongs to the WD repeat EMAP family.
messages: May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.

9755:LOC102984872
gene id: 9755:LOC102984872
uniprot id: A0A2Y9T2A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:MRPL35
gene id: 9755:MRPL35
uniprot id: A0A2Y9ELG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bL35 family.
messages: Mitochondrion

9755:CCND1
gene id: 9755:CCND1
uniprot id: A0A2Y9TJV6
names: Similarity
messages: Belongs to the cyclin family.

9755:SLC4A8
gene id: 9755:SLC4A8
uniprot id: A0A2Y9SQI9
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane

9755:FGF13
gene id: 9755:FGF13
uniprot id: A0A2Y9ERK5
uniprot id: A0A2Y9SZ68
uniprot id: A0A455AN31
uniprot id: A0A455APR3
uniprot id: A0A455APR7
uniprot id: A0A455AQ60
uniprot id: A0A455B1X0
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9755:DDX6
gene id: 9755:DDX6
uniprot id: A0A2Y9TB64
names: Similarity
messages: Belongs to the DEAD box helicase family.

9755:EMC2
gene id: 9755:EMC2
uniprot id: A0A2Y9FH46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC2 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.

9755:CABIN1
gene id: 9755:CABIN1
uniprot id: A0A455AUZ6
names: Subcellular Location Annotation
messages: Nucleus

9755:ARSG
gene id: 9755:ARSG
uniprot id: A0A2Y9T588
uniprot id: A0A2Y9TB53
names: Similarity
messages: Belongs to the sulfatase family.

9755:MFSD14A
gene id: 9755:MFSD14A
uniprot id: A0A2Y9F6U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

9755:LOC102992045
gene id: 9755:LOC102992045
uniprot id: A0A455C1G3
names: Similarity
messages: Belongs to the mesothelin family.

9755:MMP7
gene id: 9755:MMP7
uniprot id: A0A2Y9S592
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

9755:EDNRB
gene id: 9755:EDNRB
uniprot id: A0A2Y9FC67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9755:SNCB
gene id: 9755:SNCB
uniprot id: A0A2Y9EK44
names: Similarity
messages: Belongs to the synuclein family.

9755:HNF1B
gene id: 9755:HNF1B
uniprot id: A0A2Y9EWV7
uniprot id: A0A2Y9EWW3
uniprot id: A0A2Y9EYT3
uniprot id: A0A455C2D4
uniprot id: A0A455C2N5
uniprot id: A0A455C3H2
uniprot id: A0A455CB03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HNF1 homeobox family.
messages: Nucleus

9755:SLC39A2
gene id: 9755:SLC39A2
uniprot id: A0A2Y9EMV0
names: Subcellular Location Annotation
messages: Membrane

9755:RNASE10
gene id: 9755:RNASE10
uniprot id: A0A2Y9FRK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

9755:BGN
gene id: 9755:BGN
uniprot id: A0A2Y9F584
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: May be involved in collagen fiber assembly.
messages: extracellular matrix

9755:SLC45A1
gene id: 9755:SLC45A1
uniprot id: A0A2Y9ST21
names: Subcellular Location Annotation
messages: Membrane

9755:YPEL5
gene id: 9755:YPEL5
uniprot id: A0A2Y9F583
names: Similarity
messages: Belongs to the yippee family.

9755:RNF152
gene id: 9755:RNF152
uniprot id: A0A2Y9FAH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNF152 family.
messages: Lysosome membrane
messages: Membrane

9755:CRYGN
gene id: 9755:CRYGN
uniprot id: A0A455BQE8
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

9755:ADAMTS2
gene id: 9755:ADAMTS2
uniprot id: A0A2Y9S7G1
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9755:BTF3
gene id: 9755:BTF3
uniprot id: A0A2Y9F2N8
uniprot id: A0A2Y9F2S1
names: Similarity
messages: Belongs to the NAC-beta family.

9755:BAAT
gene id: 9755:BAAT
uniprot id: A0A2Y9FBQ1
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

9755:DPH3
gene id: 9755:DPH3
uniprot id: A0A2Y9EIK3
uniprot id: A0A455BAE6
names: Similarity
messages: Belongs to the DPH3 family.

9755:LOC102979058
gene id: 9755:LOC102979058
uniprot id: A0A455AB92
uniprot id: A0A455AB96
uniprot id: A0A455ABD8
uniprot id: A0A455ADG8
uniprot id: A0A455AN08
names: Subcellular Location Annotation
messages: Membrane

9755:SCAND1
gene id: 9755:SCAND1
uniprot id: A0A2Y9EHL4
names: Subcellular Location Annotation
messages: Nucleus

9755:MFSD11
gene id: 9755:MFSD11
uniprot id: A0A455C0S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

9755:CNOT1
gene id: 9755:CNOT1
uniprot id: A0A2Y9F0Q4
uniprot id: A0A2Y9F0X1
uniprot id: A0A2Y9F229
uniprot id: A0A2Y9SQB5
uniprot id: A0A2Y9STV6
uniprot id: A0A2Y9SWC6
uniprot id: A0A455AF73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT1 family.
messages: Nucleus

9755:MDFIC2
gene id: 9755:MDFIC2
uniprot id: A0A2Y9SMH6
names: Similarity
messages: Belongs to the MDFI family.

9755:PGAP1
gene id: 9755:PGAP1
uniprot id: A0A2Y9F6R6
uniprot id: A0A2Y9F722
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI inositol-deacylase family.
messages: Endoplasmic reticulum membrane
messages: Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:ADD2
gene id: 9755:ADD2
uniprot id: A0A2Y9FR55
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

9755:FN3K
gene id: 9755:FN3K
uniprot id: A0A2Y9FKX6
names: Similarity
messages: Belongs to the fructosamine kinase family.

9755:HMX3
gene id: 9755:HMX3
uniprot id: A0A2Y9SKQ3
names: Subcellular Location Annotation
messages: Nucleus

9755:KYNU
gene id: 9755:KYNU
uniprot id: A0A2Y9FHI6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:AGBL4
gene id: 9755:AGBL4
uniprot id: A0A455B5D1
names: Similarity
messages: Belongs to the peptidase M14 family.

9755:CCS
gene id: 9755:CCS
uniprot id: A0A2Y9F6F6
names: Similarity
messages: In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family.

9755:ITIH3
gene id: 9755:ITIH3
uniprot id: A0A2Y9F9V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

9755:LOC102982355
gene id: 9755:LOC102982355
uniprot id: A0A2Y9T855
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:ELAVL2
gene id: 9755:ELAVL2
uniprot id: A0A2Y9TEC0
names: Similarity
messages: Belongs to the RRM elav family.

9755:PPIL3
gene id: 9755:PPIL3
uniprot id: A0A2Y9ET48
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

9755:ATP5PB
gene id: 9755:ATP5PB
uniprot id: A0A2Y9SI60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ATPase B chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion
messages: Mitochondrion inner membrane

9755:CRYBA1
gene id: 9755:CRYBA1
uniprot id: A0A2Y9FFR3
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

9755:PGBD1
gene id: 9755:PGBD1
uniprot id: A0A2Y9EPJ5
names: Subcellular Location Annotation
messages: Nucleus

9755:LOC102988126
gene id: 9755:LOC102988126
uniprot id: A0A455CAQ4
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

9755:PAPOLB
gene id: 9755:PAPOLB
uniprot id: A0A2Y9FUI0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Binds 2 magnesium ions. Also active with manganese.
messages: Nucleus
messages: Polymerase that creates the 3'-poly(A) tail of mRNA's.

9755:IL2RB
gene id: 9755:IL2RB
uniprot id: A0A2Y9F029
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Cell membrane
messages: Membrane
messages: Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit. Interacts with SHB upon interleukin stimulation.

9755:RBM48
gene id: 9755:RBM48
uniprot id: A0A2Y9EJ41
names: Function
names: Similarity
names: Subunit
messages: As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.
messages: Belongs to the RBM48 family.
messages: Component of the minor spliceosome. Within this complex, interacts with ARMC7 and PRPF8/PRP8.

9755:TSHR
gene id: 9755:TSHR
uniprot id: A0A2Y9F3I2
uniprot id: A0A455BSU6
uniprot id: A0A455BTI7
uniprot id: A0A455BW86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Basolateral cell membrane
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Interacts with heterodimer GPHA2:GPHB5; this interaction stimulates cAMP production. Interacts (via the PDZ-binding motif) with SCRIB; regulates TSHR trafficking and function.
messages: Lateral cell membrane
messages: Membrane
messages: Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.

9755:FSIP1
gene id: 9755:FSIP1
uniprot id: A0A2Y9TDW9
names: Similarity
messages: Belongs to the FSIP1 family.

9755:LOC102983740
gene id: 9755:LOC102983740
uniprot id: A0A2Y9EXW6
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

9755:LOC112065900
gene id: 9755:LOC112065900
uniprot id: A0A2Y9T1C8
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

9755:LRRC7
gene id: 9755:LRRC7
uniprot id: A0A455B8E8
uniprot id: A0A455B8F3
uniprot id: A0A455B8S9
uniprot id: A0A455BAS6
uniprot id: A0A455BAT2
uniprot id: A0A455BME4
names: Similarity
messages: Belongs to the LAP (LRR and PDZ) protein family.

9755:MAML1
gene id: 9755:MAML1
uniprot id: A0A2Y9S3V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

9755:ABCC8
gene id: 9755:ABCC8
uniprot id: A0A455C6K4
uniprot id: A0A455C6K9
uniprot id: A0A455C6T5
uniprot id: A0A455C6U0
uniprot id: A0A455C7I9
uniprot id: A0A455C9C9
uniprot id: A0A455C9D2
uniprot id: A0A455CBU7
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with KCNJ11.
messages: Membrane

9755:NPEPPS
gene id: 9755:NPEPPS
uniprot id: A0A2Y9TCN5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Membrane

9755:LPAR2
gene id: 9755:LPAR2
uniprot id: A0A2Y9F836
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9755:KIF6
gene id: 9755:KIF6
uniprot id: A0A455AIG5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9755:C19H18orf32
gene id: 9755:C19H18orf32
uniprot id: A0A2Y9FHY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UPF0729 family.
messages: Interacts with DERL1 and AMFR.
messages: Lipid droplet
messages: May activate the NF-kappa-B signaling pathway.

9755:TOR1B
gene id: 9755:TOR1B
uniprot id: A0A2Y9EJQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.
messages: Endoplasmic reticulum lumen

9755:COPS4
gene id: 9755:COPS4
uniprot id: A0A2Y9FP20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN4 family.
messages: Nucleus
messages: Vesicle
messages: synaptic vesicle

9755:LOC102981498
gene id: 9755:LOC102981498
uniprot id: A0A2Y9SXJ4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

9755:GGH
gene id: 9755:GGH
uniprot id: A0A2Y9SW27
uniprot id: A0A2Y9SZW7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

9755:LYPLA2
gene id: 9755:LYPLA2
uniprot id: A0A2Y9FEH6
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

9755:ANKS6
gene id: 9755:ANKS6
uniprot id: A0A2Y9SU89
uniprot id: A0A2Y9SY33
uniprot id: A0A455BKQ6
names: Function
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

9755:SNAPC3
gene id: 9755:SNAPC3
uniprot id: A0A2Y9SV93
uniprot id: A0A2Y9SZ05
uniprot id: A0A455C1F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNAPC3/SRD2 family.
messages: Nucleus
messages: Part of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC3 interacts with SNAPC1.
messages: Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.

9755:NOL11
gene id: 9755:NOL11
uniprot id: A0A2Y9FMK5
names: Subcellular Location Annotation
messages: nucleolus

9755:PRPF4B
gene id: 9755:PRPF4B
uniprot id: A0A2Y9SNY7
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.
messages: Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF.

9755:LOC102979220
gene id: 9755:LOC102979220
uniprot id: A0A2Y9SGP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H3 family.
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus

9755:PRSS12
gene id: 9755:PRSS12
uniprot id: A0A2Y9F5V8
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations.
messages: Secreted

9755:PARD3B
gene id: 9755:PARD3B
uniprot id: A0A2Y9SNN0
uniprot id: A0A455ALV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR3 family.
messages: Cell junction
messages: Endomembrane system

9755:YAE1
gene id: 9755:YAE1
uniprot id: A0A2Y9FNT7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9755:IL3RA
gene id: 9755:IL3RA
uniprot id: A0A455BWT5
names: Subcellular Location Annotation
messages: Membrane

9755:SPHKAP
gene id: 9755:SPHKAP
uniprot id: A0A2Y9EEC9
names: Similarity
messages: Belongs to the AKAP110 family.

9755:NETO1
gene id: 9755:NETO1
uniprot id: A0A2Y9FES2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:HEG1
gene id: 9755:HEG1
uniprot id: A0A2Y9STY3
uniprot id: A0A455BIZ2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:TGFBR2
gene id: 9755:TGFBR2
uniprot id: A0A2Y9S4G6
uniprot id: A0A455ADK4
uniprot id: A0A455AQU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFRB1 by the constitutively active TGFBR2. Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4. The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes. This constitutes the canonical SMAD-dependent TGF-beta signaling cascade. Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways.

9755:ATP6V1C1
gene id: 9755:ATP6V1C1
uniprot id: A0A2Y9F0W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits.

9755:MOCS2
gene id: 9755:MOCS2
uniprot id: A0A2Y9FXY7
uniprot id: A0A2Y9SK88
uniprot id: A0A455BLF0
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MoaE family. MOCS2B subfamily.
messages: Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
messages: Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein is produced by a bicistronic gene which also produces the small subunit (MOCS2A) from an overlapping reading frame.
messages: cytosol

9755:ALG2
gene id: 9755:ALG2
uniprot id: A0A2Y9SVU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.
messages: Membrane

9755:EVC
gene id: 9755:EVC
uniprot id: A0A2Y9S946
uniprot id: A0A2Y9SFV6
names: Subcellular Location Annotation
messages: Membrane
messages: cilium basal body
messages: cilium membrane

9755:HS3ST4
gene id: 9755:HS3ST4
uniprot id: A0A2Y9SUA7
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9755:TPM2
gene id: 9755:TPM2
uniprot id: A0A2Y9ETA1
uniprot id: A0A2Y9EUK5
uniprot id: A0A2Y9EV87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

9755:LOC102984211
gene id: 9755:LOC102984211
uniprot id: A0A2Y9F0K4
uniprot id: A0A2Y9F0Z6
uniprot id: A0A2Y9F1U0
names: Similarity
messages: Belongs to the HPF1 family.

9755:ACSM5
gene id: 9755:ACSM5
uniprot id: A0A2Y9SS34
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

9755:SKIC2
gene id: 9755:SKIC2
uniprot id: A0A2Y9EX18
names: Subcellular Location Annotation
messages: Cytoplasm

9755:KIF3B
gene id: 9755:KIF3B
uniprot id: A0A2Y9FGM5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9755:LOC102975756
gene id: 9755:LOC102975756
uniprot id: A0A2Y9F0C7
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

9755:SIAH2
gene id: 9755:SIAH2
uniprot id: A0A2Y9EDH7
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

9755:MED7
gene id: 9755:MED7
uniprot id: A0A2Y9EKJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 7 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
messages: Component of the Mediator complex.
messages: Nucleus

9755:CEP70
gene id: 9755:CEP70
uniprot id: A0A455B8B5
uniprot id: A0A455B8C5
uniprot id: A0A455BB68
uniprot id: A0A455BB72
uniprot id: A0A455BMW3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Directly interacts with tubulin-gamma; this interaction determines centrosomal localization.
messages: Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle.
messages: centrosome

9755:APOM
gene id: 9755:APOM
uniprot id: A0A2Y9EW38
uniprot id: A0A455AFY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family. Highly divergent.
messages: Interacts with LRP2; LRP2 mediates APOM renal uptake and subsequent lysosomal degradation.
messages: Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid.
messages: Secreted

9755:PAXBP1
gene id: 9755:PAXBP1
uniprot id: A0A2Y9SJF8
names: Similarity
messages: Belongs to the GCF family.

9755:AKNAD1
gene id: 9755:AKNAD1
uniprot id: A0A2Y9SDP0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.

9755:RIPPLY3
gene id: 9755:RIPPLY3
uniprot id: A0A2Y9FK37
uniprot id: A0A455BKI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ripply family.
messages: Nucleus

9755:ATP23
gene id: 9755:ATP23
uniprot id: A0A2Y9SJM0
uniprot id: A0A2Y9SK89
uniprot id: A0A2Y9SMZ0
uniprot id: A0A2Y9SQZ1
uniprot id: A0A455BE27
uniprot id: A0A455BT23
names: Similarity
messages: Belongs to the peptidase M76 family.

9755:PVALEF
gene id: 9755:PVALEF
uniprot id: A0A2Y9T8A4
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

9755:KLHL22
gene id: 9755:KLHL22
uniprot id: A0A2Y9SLE5
names: Subcellular Location Annotation
messages: Lysosome
messages: Nucleus
messages: centrosome
messages: cytosol
messages: spindle

9755:GPR132
gene id: 9755:GPR132
uniprot id: A0A2Y9T8V9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9755:LY75
gene id: 9755:LY75
uniprot id: A0A2Y9SQR7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:BMX
gene id: 9755:BMX
uniprot id: A0A455BU34
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

9755:LOC114484417
gene id: 9755:LOC114484417
uniprot id: A0A455AWX9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.

9755:GRM8
gene id: 9755:GRM8
uniprot id: A0A2Y9T644
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

9755:LOC102979011
gene id: 9755:LOC102979011
uniprot id: A0A2Y9FIJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Secreted

9755:ALG14
gene id: 9755:ALG14
uniprot id: A0A2Y9SE40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG14 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane

9755:LOC102980967
gene id: 9755:LOC102980967
uniprot id: A0A2Y9EE73
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

9755:GRIK1
gene id: 9755:GRIK1
uniprot id: A0A2Y9FCV2
uniprot id: A0A2Y9SBC9
uniprot id: A0A2Y9SBD2
uniprot id: A0A2Y9SC37
uniprot id: A0A2Y9SC42
uniprot id: A0A2Y9SF76
uniprot id: A0A2Y9SI29
uniprot id: A0A2Y9SJN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

9755:LOC102978307
gene id: 9755:LOC102978307
uniprot id: A0A2Y9FCT0
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9755:PCNT
gene id: 9755:PCNT
uniprot id: A0A455BIB2
uniprot id: A0A455BXM0
uniprot id: A0A455BXM9
names: Subcellular Location Annotation
messages: centrosome

9755:TIGD2
gene id: 9755:TIGD2
uniprot id: A0A2Y9EM00
names: Subcellular Location Annotation
messages: Nucleus

9755:SOD2
gene id: 9755:SOD2
uniprot id: A0A2Y9FMN4
uniprot id: A0A455BNR2
uniprot id: A0A455BRY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Homotetramer.
messages: Mitochondrion matrix

9755:LDHB
gene id: 9755:LDHB
uniprot id: A0A2Y9T3J5
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

9755:MTFR1L
gene id: 9755:MTFR1L
uniprot id: A0A2Y9SS26
uniprot id: A0A2Y9SWS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

9755:LOC102987499
gene id: 9755:LOC102987499
uniprot id: A0A2Y9THH0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:LOC102986844
gene id: 9755:LOC102986844
uniprot id: A0A2Y9FT26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTF2H2 family.
messages: Nucleus

9755:NIPAL1
gene id: 9755:NIPAL1
uniprot id: A0A2Y9F5R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

9755:ATP1B4
gene id: 9755:ATP1B4
uniprot id: A0A2Y9F6C8
uniprot id: A0A2Y9F6H6
uniprot id: A0A455B268
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

9755:C2H2orf88
gene id: 9755:C2H2orf88
uniprot id: A0A2Y9EM78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small membrane AKAP family.
messages: Cell membrane
messages: Membrane

9755:NEU3
gene id: 9755:NEU3
uniprot id: A0A2Y9EGH6
uniprot id: A0A2Y9EGN5
uniprot id: A0A455C7Q0
uniprot id: A0A455C8C6
uniprot id: A0A455C9T8
uniprot id: A0A455CC23
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

9755:FASN
gene id: 9755:FASN
uniprot id: A0A2Y9T899
names: Function
messages: Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ([ACP]) domain.

9755:FRAS1
gene id: 9755:FRAS1
uniprot id: A0A2Y9S173
uniprot id: A0A455BFL8
uniprot id: A0A455BFM5
uniprot id: A0A455BG31
uniprot id: A0A455BG37
uniprot id: A0A455BG85
uniprot id: A0A455BG93
uniprot id: A0A455BIP6
uniprot id: A0A455BVA2
uniprot id: A0A455BVA7
uniprot id: A0A455BVB4
names: Similarity
messages: Belongs to the FRAS1 family.

9755:DAZL
gene id: 9755:DAZL
uniprot id: A0A2Y9ETG1
names: Subcellular Location Annotation
messages: Cytoplasm

9755:MYO1H
gene id: 9755:MYO1H
uniprot id: A0A2Y9SCW4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

9755:DARS1
gene id: 9755:DARS1
uniprot id: A0A2Y9FS22
names: Function
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.

9755:RPA4
gene id: 9755:RPA4
uniprot id: A0A2Y9EMD1
names: Similarity
messages: Belongs to the replication factor A protein 2 family.

9755:POLR3G
gene id: 9755:POLR3G
uniprot id: A0A2Y9ST91
uniprot id: A0A2Y9SVL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC7 RNA polymerase subunit family.
messages: Nucleus

9755:TIMM9
gene id: 9755:TIMM9
uniprot id: A0A2Y9EMT0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

9755:LOC102983088
gene id: 9755:LOC102983088
uniprot id: A0A2Y9F641
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FUN14 family.
messages: Mitochondrion outer membrane

9755:NUBP2
gene id: 9755:NUBP2
uniprot id: A0A2Y9EEQ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
messages: Cytoplasm
messages: Heterotetramer of 2 NUBP1 and 2 NUBP2 chains. Interacts with KIFC1.
messages: Nucleus
messages: centrosome

9755:SLC25A53
gene id: 9755:SLC25A53
uniprot id: A0A2Y9FD46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9755:ADRA1D
gene id: 9755:ADRA1D
uniprot id: A0A2Y9FFW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with FLNA (via filamin repeat 21); increases PKA-mediated phosphorylation of FLNA.
messages: Membrane
messages: This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.

9755:SLC35C1
gene id: 9755:SLC35C1
uniprot id: A0A2Y9FJE9
uniprot id: A0A2Y9FJN2
names: Subcellular Location Annotation
messages: Membrane

9755:GRM6
gene id: 9755:GRM6
uniprot id: A0A2Y9S065
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

9755:TM4SF1
gene id: 9755:TM4SF1
uniprot id: A0A2Y9EY96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

9755:FABP6
gene id: 9755:FABP6
uniprot id: A0A2Y9RZ31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm

9755:CRYBG1
gene id: 9755:CRYBG1
uniprot id: A0A2Y9FAY7
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

9755:PLAA
gene id: 9755:PLAA
uniprot id: A0A2Y9EV78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PLAP family.
messages: Cytoplasm

9755:CEP57
gene id: 9755:CEP57
uniprot id: A0A2Y9RXP6
uniprot id: A0A2Y9S0T9
names: Similarity
messages: Belongs to the translokin family.

9755:OTX1
gene id: 9755:OTX1
uniprot id: A0A2Y9ESF0
names: Subcellular Location Annotation
messages: Nucleus

9755:DRD4
gene id: 9755:DRD4
uniprot id: A0A2Y9TAS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9755:SAMHD1
gene id: 9755:SAMHD1
uniprot id: A0A2Y9F7R1
uniprot id: A0A2Y9F7T3
uniprot id: A0A2Y9F9D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAMHD1 family.
messages: Chromosome

9755:LAP3
gene id: 9755:LAP3
uniprot id: A0A2Y9EH99
names: Similarity
names: Subunit
messages: Belongs to the peptidase M17 family.
messages: Homohexamer.

9755:TRH
gene id: 9755:TRH
uniprot id: A0A2Y9SMF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRH family.
messages: Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
messages: Secreted

9755:LOC102995560
gene id: 9755:LOC102995560
uniprot id: A0A2Y9F2Q7
uniprot id: A0A455C822
names: Similarity
messages: Belongs to the folate receptor family.

9755:MAF1
gene id: 9755:MAF1
uniprot id: A0A2Y9FA51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAF1 family.
messages: Element of the TORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.
messages: Nucleus

9755:LOC102975060
gene id: 9755:LOC102975060
uniprot id: A0A2Y9FQM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCR10/QCR9 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

9755:METTL15
gene id: 9755:METTL15
uniprot id: A0A2Y9SGA0
uniprot id: A0A455C690
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmH family.

9755:RCL1
gene id: 9755:RCL1
uniprot id: A0A2Y9F137
uniprot id: A0A2Y9F1V3
uniprot id: A0A455BL99
uniprot id: A0A455BLI4
uniprot id: A0A455BPI1
uniprot id: A0A455C188
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
messages: Part of the small subunit (SSU) processome, composed of more than 70 proteins and the RNA chaperone small nucleolar RNA (snoRNA) U3.
messages: nucleolus

9755:OVCH2
gene id: 9755:OVCH2
uniprot id: A0A2Y9ESN4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:ST8SIA5
gene id: 9755:ST8SIA5
uniprot id: A0A455AI84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9755:LOC102995106
gene id: 9755:LOC102995106
uniprot id: A0A455BVJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC9 RNA polymerase subunit family.
messages: Nucleus

9755:GDPGP1
gene id: 9755:GDPGP1
uniprot id: A0A2Y9SB36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDPGP1 family.
messages: Cytoplasm
messages: Specific and highly efficient GDP-D-glucose phosphorylase regulating the levels of GDP-D-glucose in cells.

9755:METTL16
gene id: 9755:METTL16
uniprot id: A0A455C0X7
uniprot id: A0A455CAN7
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: RNA N6-methyltransferase that methylates adenosine residues at the N(6) position of a subset of RNAs and is involved in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6-methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure.

9755:ACTL8
gene id: 9755:ACTL8
uniprot id: A0A2Y9EL48
names: Similarity
messages: Belongs to the actin family.

9755:DTX3L
gene id: 9755:DTX3L
uniprot id: A0A2Y9F978
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

9755:IRX3
gene id: 9755:IRX3
uniprot id: A0A2Y9SW24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

9755:WASHC3
gene id: 9755:WASHC3
uniprot id: A0A455BQZ9
names: Similarity
messages: Belongs to the CCDC53 family.

9755:UBE3C
gene id: 9755:UBE3C
uniprot id: A0A455BBH7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:PROS1
gene id: 9755:PROS1
uniprot id: A0A2Y9EH60
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:WWP1
gene id: 9755:WWP1
uniprot id: A0A455CBC9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:CTU1
gene id: 9755:CTU1
uniprot id: A0A2Y9TB98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
messages: Component of a complex at least composed of URM1, CTU2/NCS2 and CTU1/ATPBD3. May form a heterodimer with CTU2/NCS2.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

9755:NRG4
gene id: 9755:NRG4
uniprot id: A0A455BT01
names: Caution
names: Similarity
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:CWC25
gene id: 9755:CWC25
uniprot id: A0A2Y9T4D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CWC25 family.
messages: Nucleus

9755:LOC102991479
gene id: 9755:LOC102991479
uniprot id: A0A2Y9SCB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

9755:PSD2
gene id: 9755:PSD2
uniprot id: A0A455BJU5
names: Subcellular Location Annotation
messages: Membrane
messages: ruffle membrane

9755:CA1
gene id: 9755:CA1
uniprot id: A0A2Y9F8S5
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

9755:DBNL
gene id: 9755:DBNL
uniprot id: A0A2Y9F4U9
uniprot id: A0A455BQB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABP1 family.
messages: Early endosome
messages: Golgi apparatus membrane
messages: Perikaryon
messages: Postsynaptic density
messages: cell cortex
messages: clathrin-coated vesicle membrane
messages: dendrite
messages: lamellipodium
messages: neuron projection
messages: podosome
messages: ruffle

9755:PRDM1
gene id: 9755:PRDM1
uniprot id: A0A2Y9EKU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Interacts with PRMT5. Interacts with FBXO10. Interacts with FBXO11.
messages: Nucleus
messages: Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection. Binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells. Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions.

9755:ABRAXAS1
gene id: 9755:ABRAXAS1
uniprot id: A0A2Y9RXV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM175 family. Abraxas subfamily.
messages: Nucleus

9755:GPR12
gene id: 9755:GPR12
uniprot id: A0A2Y9EYC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9755:TM9SF2
gene id: 9755:TM9SF2
uniprot id: A0A2Y9EJP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

9755:GATA2
gene id: 9755:GATA2
uniprot id: A0A2Y9S9T9
names: Subcellular Location Annotation
messages: Nucleus

9755:LOC112062707
gene id: 9755:LOC112062707
uniprot id: A0A2Y9SAV3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

9755:PENK
gene id: 9755:PENK
uniprot id: A0A455CBG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Neuropeptide that competes with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress.
messages: Secreted
messages: chromaffin granule lumen

9755:EMP1
gene id: 9755:EMP1
uniprot id: A0A455BG05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

9755:LTV1
gene id: 9755:LTV1
uniprot id: A0A2Y9EGC7
uniprot id: A0A455BQQ4
names: Similarity
messages: Belongs to the LTV1 family.

9755:CNKSR2
gene id: 9755:CNKSR2
uniprot id: A0A2Y9FM26
uniprot id: A0A2Y9FM74
uniprot id: A0A2Y9FNN5
uniprot id: A0A2Y9FPL6
uniprot id: A0A2Y9S4D9
uniprot id: A0A455APS8
uniprot id: A0A455B3F9
names: Similarity
messages: Belongs to the CNKSR family.

9755:ITGB7
gene id: 9755:ITGB7
uniprot id: A0A2Y9FKX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Melanosome
messages: Membrane
messages: Recycling endosome
messages: focal adhesion
messages: invadopodium membrane
messages: lamellipodium
messages: ruffle membrane

9755:IL2
gene id: 9755:IL2
uniprot id: A0A2Y9F6D3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-2 family.
messages: Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer (NK) cells that plays pivotal roles in the immune response and tolerance. Binds to a receptor complex composed of either the high-affinity trimeric IL-2R (IL2RA/CD25, IL2RB/CD122 and IL2RG/CD132) or the low-affinity dimeric IL-2R (IL2RB and IL2RG). Interaction with the receptor leads to oligomerization and conformation changes in the IL-2R subunits resulting in downstream signaling starting with phosphorylation of JAK1 and JAK3. In turn, JAK1 and JAK3 phosphorylate the receptor to form a docking site leading to the phosphorylation of several substrates including STAT5. This process leads to activation of several pathways including STAT, phosphoinositide-3-kinase/PI3K and mitogen-activated protein kinase/MAPK pathways. Functions as a T-cell growth factor and can increase NK-cell cytolytic activity as well. Promotes strong proliferation of activated B-cells and subsequently immunoglobulin production. Plays a pivotal role in regulating the adaptive immune system by controlling the survival and proliferation of regulatory T-cells, which are required for the maintenance of immune tolerance. Moreover, participates in the differentiation and homeostasis of effector T-cell subsets, including Th1, Th2, Th17 as well as memory CD8-positive T-cells.
messages: Secreted

9755:DTD1
gene id: 9755:DTD1
uniprot id: A0A2Y9F4A2
uniprot id: A0A2Y9F601
uniprot id: A0A2Y9SL58
uniprot id: A0A2Y9SSF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DTD family.
messages: Cytoplasm

9755:PEX16
gene id: 9755:PEX16
uniprot id: A0A2Y9FJF4
uniprot id: A0A2Y9TH44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-16 family.
messages: Peroxisome membrane

9755:TET3
gene id: 9755:TET3
uniprot id: A0A2Y9TED0
uniprot id: A0A2Y9TK54
uniprot id: A0A455BX21
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TET family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Chromosome
messages: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development.
messages: The zinc ions have a structural role.

9755:SNRPG
gene id: 9755:SNRPG
uniprot id: A0A2Y9FTV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing.
messages: cytosol

9755:SLC5A1
gene id: 9755:SLC5A1
uniprot id: A0A2Y9FQZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

9755:CAMSAP2
gene id: 9755:CAMSAP2
uniprot id: A0A2Y9T673
uniprot id: A0A2Y9TC67
uniprot id: A0A2Y9TE92
uniprot id: A0A455B556
uniprot id: A0A455B626
uniprot id: A0A455B7U1
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

9755:ZBED6
gene id: 9755:ZBED6
uniprot id: A0A455B5Z9
names: Subcellular Location Annotation
messages: Nucleus

9755:B4GALT3
gene id: 9755:B4GALT3
uniprot id: A0A2Y9RZP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

9755:TERT
gene id: 9755:TERT
uniprot id: A0A2Y9SLU6
uniprot id: A0A2Y9SMN4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reverse transcriptase family. Telomerase subfamily.
messages: Cytoplasm
messages: Nucleus
messages: PML body
messages: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nucleotide telomeric repeat unit, 5'-TTAGGG-3'. The catalytic cycle involves primer binding, primer extension and release of product once the template boundary has been reached or nascent product translocation followed by further extension. More active on substrates containing 2 or 3 telomeric repeats. Telomerase activity is regulated by a number of factors including telomerase complex-associated proteins, chaperones and polypeptide modifiers. Modulates Wnt signaling. Plays important roles in aging and antiapoptosis.
messages: The RNA-interacting domain 1 (RD1)/N-terminal extension (NTE) is required for interaction with the pseudoknot-template domain of each of TERC dimers. It contains anchor sites that bind primer nucleotides upstream of the RNA-DNA hybrid and is thus an essential determinant of repeat addition processivity.
messages: The RNA-interacting domain 2 (RD2) is essential for both interaction with the CR4-CR5 domain of TERC and for DNA synthesis.
messages: The primer grip sequence in the RT domain is required for telomerase activity and for stable association with short telomeric primers.
messages: nucleolus
messages: nucleoplasm
messages: telomere

9755:BCORL1
gene id: 9755:BCORL1
uniprot id: A0A2Y9EIL4
uniprot id: A0A455APF4
uniprot id: A0A455ARB1
names: Similarity
messages: Belongs to the BCOR family.

9755:MCCC2
gene id: 9755:MCCC2
uniprot id: A0A2Y9FT02
names: Similarity
messages: Belongs to the AccD/PCCB family.

9755:EFHC2
gene id: 9755:EFHC2
uniprot id: A0A2Y9S0U9
names: Subcellular Location Annotation
messages: cilium axoneme

9755:TUBB6
gene id: 9755:TUBB6
uniprot id: A0A2Y9SH24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

9755:NDUFA8
gene id: 9755:NDUFA8
uniprot id: A0A2Y9FKB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA8 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

9755:DTNBP1
gene id: 9755:DTNBP1
uniprot id: A0A2Y9SNF2
names: Similarity
messages: Belongs to the dysbindin family.

9755:NOL6
gene id: 9755:NOL6
uniprot id: A0A2Y9EY93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAP family.
messages: Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
messages: nucleolus

9755:ALDH3A1
gene id: 9755:ALDH3A1
uniprot id: A0A455C794
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

9755:TEX13B
gene id: 9755:TEX13B
uniprot id: A0A2Y9SYS5
names: Similarity
messages: Belongs to the TEX13 family.

9755:ATP6V0D2
gene id: 9755:ATP6V0D2
uniprot id: A0A2Y9FEX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

9755:LOC112065907
gene id: 9755:LOC112065907
uniprot id: A0A2Y9T545
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Divalent metal ions. Mg(2+) is the most effective.

9755:HS6ST1
gene id: 9755:HS6ST1
uniprot id: A0A2Y9S002
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

9755:VSTM5
gene id: 9755:VSTM5
uniprot id: A0A2Y9F962
names: Subcellular Location Annotation
messages: Membrane

9755:RIPOR3
gene id: 9755:RIPOR3
uniprot id: A0A2Y9FPF9
names: Similarity
messages: Belongs to the RIPOR family.

9755:PPP1R14A
gene id: 9755:PPP1R14A
uniprot id: A0A2Y9TI63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP1 inhibitor family.
messages: Cytoplasm
messages: Inhibitor of PPP1CA.

9755:FAM131A
gene id: 9755:FAM131A
uniprot id: A0A2Y9FG82
uniprot id: A0A2Y9SU56
uniprot id: A0A455BI20
names: Similarity
messages: Belongs to the FAM131 family.

9755:MAGI2
gene id: 9755:MAGI2
uniprot id: A0A2Y9RZE4
names: Subcellular Location Annotation
messages: Membrane

9755:RCAN1
gene id: 9755:RCAN1
uniprot id: A0A2Y9FS58
names: Similarity
messages: Belongs to the RCAN family.

9755:KCNAB2
gene id: 9755:KCNAB2
uniprot id: A0A455B452
uniprot id: A0A455BIE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

9755:IER3IP1
gene id: 9755:IER3IP1
uniprot id: A0A2Y9TCM8
names: Similarity
messages: Belongs to the YOS1 family.

9755:SEMA3C
gene id: 9755:SEMA3C
uniprot id: A0A2Y9RZF3
uniprot id: A0A2Y9S2Q7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9755:NGFR
gene id: 9755:NGFR
uniprot id: A0A2Y9TDQ1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:PALM3
gene id: 9755:PALM3
uniprot id: A0A2Y9TKS8
names: Similarity
messages: Belongs to the paralemmin family.

9755:DTYMK
gene id: 9755:DTYMK
uniprot id: A0A2Y9SP80
uniprot id: A0A2Y9SVB1
uniprot id: A0A455AU50
names: Similarity
messages: Belongs to the thymidylate kinase family.

9755:RBM47
gene id: 9755:RBM47
uniprot id: A0A2Y9FXT1
uniprot id: A0A2Y9SEH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM RBM47 family.
messages: Cytoplasm
messages: Nucleus

9755:PSMB2
gene id: 9755:PSMB2
uniprot id: A0A2Y9FIE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

9755:NUP133
gene id: 9755:NUP133
uniprot id: A0A2Y9F8Q1
uniprot id: A0A2Y9F8Q3
uniprot id: A0A2Y9FAF6
uniprot id: A0A455AN99
uniprot id: A0A455ANJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin Nup133 family.
messages: nuclear pore complex

9755:MED19
gene id: 9755:MED19
uniprot id: A0A2Y9FBV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 19 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

9755:PABIR2
gene id: 9755:PABIR2
uniprot id: A0A2Y9EEZ6
uniprot id: A0A2Y9EF00
uniprot id: A0A2Y9EFN5
uniprot id: A0A2Y9EG31
uniprot id: A0A2Y9EG36
uniprot id: A0A2Y9EGB5
uniprot id: A0A2Y9EGR2
uniprot id: A0A2Y9T0I3
uniprot id: A0A455ANX4
uniprot id: A0A455AP55
uniprot id: A0A455AQK1
uniprot id: A0A455AR15
uniprot id: A0A455B2U6
uniprot id: A0A455B2V4
names: Similarity
messages: Belongs to the FAM122 family.

9755:IL5RA
gene id: 9755:IL5RA
uniprot id: A0A2Y9SQX4
names: Subcellular Location Annotation
messages: Membrane

9755:OSBPL10
gene id: 9755:OSBPL10
uniprot id: A0A2Y9S7R5
uniprot id: A0A455AE28
uniprot id: A0A455AFT9
uniprot id: A0A455AGI5
uniprot id: A0A455ARV7
names: Similarity
messages: Belongs to the OSBP family.

9755:DEFB128
gene id: 9755:DEFB128
uniprot id: A0A2Y9T8G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

9755:RBBP7
gene id: 9755:RBBP7
uniprot id: A0A2Y9FGY0
names: Subcellular Location Annotation
messages: Nucleus

9755:THUMPD3
gene id: 9755:THUMPD3
uniprot id: A0A2Y9FFU6
names: Similarity
messages: Belongs to the methyltransferase superfamily.

9755:SRP68
gene id: 9755:SRP68
uniprot id: A0A455C272
uniprot id: A0A455CAR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP68 family.
messages: Cytoplasm
messages: nucleolus

9755:GORAB
gene id: 9755:GORAB
uniprot id: A0A2Y9F5B8
names: Similarity
messages: Belongs to the GORAB family.

9755:CTNND2
gene id: 9755:CTNND2
uniprot id: A0A2Y9F5J2
uniprot id: A0A2Y9SVD2
uniprot id: A0A455BI17
names: Similarity
messages: Belongs to the beta-catenin family.

9755:KDM3A
gene id: 9755:KDM3A
uniprot id: A0A2Y9FAW3
uniprot id: A0A2Y9FCV6
uniprot id: A0A455BYY8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM2 histone demethylase family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code.
messages: Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors.
messages: Nucleus
messages: The JmjC domain and the C6-type zinc-finger are required for the demethylation activity.

9755:ZBTB8OS
gene id: 9755:ZBTB8OS
uniprot id: A0A2Y9FLV7
uniprot id: A0A2Y9SWN1
names: Similarity
names: Subunit
messages: Belongs to the archease family.
messages: Component of the tRNA-splicing ligase complex.

9755:SDC2
gene id: 9755:SDC2
uniprot id: A0A2Y9ES42
uniprot id: A0A2Y9RZD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

9755:ETS1
gene id: 9755:ETS1
uniprot id: A0A455C602
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Cytoplasm
messages: Nucleus

9755:EPHA6
gene id: 9755:EPHA6
uniprot id: A0A2Y9SIP9
uniprot id: A0A2Y9SKB7
names: Subcellular Location Annotation
messages: Membrane

9755:LOC112066338
gene id: 9755:LOC112066338
uniprot id: A0A455BEV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

9755:KCNA2
gene id: 9755:KCNA2
uniprot id: A0A2Y9EPE4
uniprot id: A0A455BA39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.2/KCNA2 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: Presynaptic cell membrane
messages: Synaptic cell membrane
messages: lamellipodium membrane
messages: paranodal septate junction
messages: synaptosome

9755:ETFA
gene id: 9755:ETFA
uniprot id: A0A2Y9F182
uniprot id: A0A455BPR5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

9755:MPDZ
gene id: 9755:MPDZ
uniprot id: A0A2Y9SYW8
uniprot id: A0A2Y9SYX3
uniprot id: A0A455BLE6
uniprot id: A0A455BLN0
uniprot id: A0A455BLN6
uniprot id: A0A455BM32
uniprot id: A0A455BM37
uniprot id: A0A455BPM6
uniprot id: A0A455BPN1
uniprot id: A0A455C1E6
names: Subcellular Location Annotation
messages: Cell membrane
messages: tight junction

9755:TMTC2
gene id: 9755:TMTC2
uniprot id: A0A2Y9SJB7
uniprot id: A0A2Y9SMN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

9755:ELOVL7
gene id: 9755:ELOVL7
uniprot id: A0A2Y9F8T6
uniprot id: A0A2Y9T006
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Belongs to the ELO family. ELOVL7 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0-, or C26:0-CoAs. May participate to the production of saturated and polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

9755:PLA2G10
gene id: 9755:PLA2G10
uniprot id: A0A2Y9EPA2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

9755:SEC22A
gene id: 9755:SEC22A
uniprot id: A0A2Y9SK65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in vesicle transport between the ER and the Golgi complex.
messages: Membrane

9755:TENT5A
gene id: 9755:TENT5A
uniprot id: A0A2Y9TGV2
uniprot id: A0A2Y9TIR3
uniprot id: A0A455BTL1
names: Similarity
messages: Belongs to the TENT family.

9755:CCDC85C
gene id: 9755:CCDC85C
uniprot id: A0A455BT60
uniprot id: A0A455BT72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC85 family.
messages: adherens junction

9755:GPC5
gene id: 9755:GPC5
uniprot id: A0A2Y9STA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

9755:FAM110C
gene id: 9755:FAM110C
uniprot id: A0A2Y9S8D5
names: Similarity
messages: Belongs to the FAM110 family.

9755:RSL24D1
gene id: 9755:RSL24D1
uniprot id: A0A2Y9T1A6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

9755:LSM8
gene id: 9755:LSM8
uniprot id: A0A2Y9TIA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.

9755:KCNK16
gene id: 9755:KCNK16
uniprot id: A0A2Y9FT18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

9755:ANXA4
gene id: 9755:ANXA4
uniprot id: A0A2Y9TEF2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Zymogen granule membrane

9755:MTMR9
gene id: 9755:MTMR9
uniprot id: A0A2Y9T8P1
uniprot id: A0A2Y9TAA6
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

9755:SENP2
gene id: 9755:SENP2
uniprot id: A0A2Y9F740
names: Similarity
messages: Belongs to the peptidase C48 family.

9755:LOC102992448
gene id: 9755:LOC102992448
uniprot id: A0A2Y9FIH0
names: Similarity
messages: Belongs to the calcitonin family.

9755:IGHMBP2
gene id: 9755:IGHMBP2
uniprot id: A0A2Y9EMJ1
uniprot id: A0A455AE97
uniprot id: A0A455AGP8
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

9755:CLCA4
gene id: 9755:CLCA4
uniprot id: A0A2Y9F6B0
names: Similarity
messages: Belongs to the CLCR family.

9755:FUT8
gene id: 9755:FUT8
uniprot id: A0A2Y9TKT6
uniprot id: A0A455C7B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 23 family.
messages: Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.
messages: Golgi stack membrane
messages: Membrane

9755:RCE1
gene id: 9755:RCE1
uniprot id: A0A2Y9EV01
uniprot id: A0A2Y9EV38
uniprot id: A0A455C638
uniprot id: A0A455C645
uniprot id: A0A455C6C7
uniprot id: A0A455C6D6
uniprot id: A0A455C736
uniprot id: A0A455CBR4
uniprot id: A0A455CBR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U48 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:ARAF
gene id: 9755:ARAF
uniprot id: A0A2Y9EJW6
uniprot id: A0A2Y9EKG8
uniprot id: A0A2Y9ELQ9
uniprot id: A0A2Y9ELW4
uniprot id: A0A2Y9S234
uniprot id: A0A455ANR2
uniprot id: A0A455B2B1
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

9755:LOC112062359
gene id: 9755:LOC112062359
uniprot id: A0A455APJ3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.

9755:OPTN
gene id: 9755:OPTN
uniprot id: A0A2Y9FLQ9
uniprot id: A0A455BS28
uniprot id: A0A455BUP7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Golgi apparatus
messages: May act by regulating membrane trafficking and cellular morphogenesis.
messages: Recycling endosome
messages: autophagosome
messages: perinuclear region
messages: trans-Golgi network

9755:NHSL2
gene id: 9755:NHSL2
uniprot id: A0A2Y9T8T3
names: Similarity
messages: Belongs to the NHS family.

9755:AIFM1
gene id: 9755:AIFM1
uniprot id: A0A2Y9EIL9
uniprot id: A0A455APZ4
uniprot id: A0A455B3Y6
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

9755:NFYB
gene id: 9755:NFYB
uniprot id: A0A2Y9SWZ5
uniprot id: A0A455BR17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NFYB/HAP3 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.
messages: Heterotrimeric transcription factor composed of three components, NF-YA, NF-YB and NF-YC. NF-YB and NF-YC must interact and dimerize for NF-YA association and DNA binding. Interacts with C1QBP.

9755:LOC114487749
gene id: 9755:LOC114487749
uniprot id: A0A455CAY5
names: Similarity
messages: Belongs to the CLEC16A/gop-1 family.

9755:NFYA
gene id: 9755:NFYA
uniprot id: A0A2Y9FAB5
uniprot id: A0A2Y9FAF2
uniprot id: A0A2Y9FAH7
uniprot id: A0A455ADN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NFYA/HAP2 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
messages: Heterotrimer.
messages: Nucleus

9755:CFAP157
gene id: 9755:CFAP157
uniprot id: A0A455BQI0
names: Similarity
messages: Belongs to the CFAP157 family.

9755:KCNK1
gene id: 9755:KCNK1
uniprot id: A0A2Y9S5P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: Recycling endosome
messages: Synaptic cell membrane
messages: Vesicle
messages: dendrite

9755:LOC102982874
gene id: 9755:LOC102982874
uniprot id: A0A2Y9FNM0
names: Similarity
messages: Belongs to the FAM90 family.

9755:UGT8
gene id: 9755:UGT8
uniprot id: A0A2Y9S9P6
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

9755:LOC112064330
gene id: 9755:LOC112064330
uniprot id: A0A2Y9SPK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

9755:LOC102976948
gene id: 9755:LOC102976948
uniprot id: A0A2Y9S6H1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:SNTA1
gene id: 9755:SNTA1
uniprot id: A0A2Y9T413
uniprot id: A0A455C507
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

9755:GNG10
gene id: 9755:GNG10
uniprot id: A0A2Y9T281
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

9755:BPI
gene id: 9755:BPI
uniprot id: A0A2Y9F852
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

9755:BAMBI
gene id: 9755:BAMBI
uniprot id: A0A2Y9S7M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BAMBI family.
messages: Membrane
messages: Negatively regulates TGF-beta signaling.

9755:S100PBP
gene id: 9755:S100PBP
uniprot id: A0A2Y9FJL2
uniprot id: A0A2Y9FJT7
uniprot id: A0A2Y9FJU1
uniprot id: A0A455B101
uniprot id: A0A455B245
names: Subcellular Location Annotation
messages: Nucleus

9755:LOC102985766
gene id: 9755:LOC102985766
uniprot id: A0A2Y9EFC1
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

9755:CHMP5
gene id: 9755:CHMP5
uniprot id: A0A2Y9EY98
names: Similarity
messages: Belongs to the SNF7 family.

9755:SPACA3
gene id: 9755:SPACA3
uniprot id: A0A2Y9F3L4
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

9755:MEP1A
gene id: 9755:MEP1A
uniprot id: A0A2Y9FEI0
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:GCLM
gene id: 9755:GCLM
uniprot id: A0A2Y9FPJ4
uniprot id: A0A2Y9FPT2
names: Similarity
names: Subunit
messages: Belongs to the aldo/keto reductase family. Glutamate--cysteine ligase light chain subfamily.
messages: Heterodimer of a catalytic heavy chain and a regulatory light chain.

9755:NKIRAS1
gene id: 9755:NKIRAS1
uniprot id: A0A2Y9F2K6
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

9755:CACNA1B
gene id: 9755:CACNA1B
uniprot id: A0A455C162
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This alpha-1B subunit gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated' (HVA) group. They are involved in pain signaling. Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons.

9755:PRKD3
gene id: 9755:PRKD3
uniprot id: A0A2Y9EJR7
uniprot id: A0A455BUE3
uniprot id: A0A455BX52
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by DAG and phorbol esters.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Cytoplasm
messages: Membrane

9755:SYNDIG1L
gene id: 9755:SYNDIG1L
uniprot id: A0A2Y9F843
names: Similarity
messages: Belongs to the CD225/Dispanin family.

9755:NAPSA
gene id: 9755:NAPSA
uniprot id: A0A2Y9TH72
names: Similarity
messages: Belongs to the peptidase A1 family.

9755:PACS2
gene id: 9755:PACS2
uniprot id: A0A2Y9T907
uniprot id: A0A2Y9TAK3
uniprot id: A0A455BTF6
uniprot id: A0A455BU40
uniprot id: A0A455BWU4
names: Similarity
messages: Belongs to the PACS family.

9755:ST8SIA4
gene id: 9755:ST8SIA4
uniprot id: A0A2Y9SKI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9755:EMC1
gene id: 9755:EMC1
uniprot id: A0A2Y9ELP5
uniprot id: A0A2Y9EMH0
uniprot id: A0A2Y9EMP3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC1 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:GNPNAT1
gene id: 9755:GNPNAT1
uniprot id: A0A2Y9FDM0
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. GNA1 subfamily.
messages: Homodimer.

9755:SLC39A3
gene id: 9755:SLC39A3
uniprot id: A0A2Y9TFS9
uniprot id: A0A455C8X7
uniprot id: A0A455CBM5
names: Subcellular Location Annotation
messages: Membrane

9755:ELF2
gene id: 9755:ELF2
uniprot id: A0A2Y9EJ68
uniprot id: A0A2Y9EJV6
uniprot id: A0A2Y9EKH4
uniprot id: A0A2Y9EL38
uniprot id: A0A2Y9EL94
uniprot id: A0A2Y9EL97
uniprot id: A0A2Y9S905
uniprot id: A0A2Y9SC86
uniprot id: A0A2Y9SF54
uniprot id: A0A2Y9SGQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9755:GPCPD1
gene id: 9755:GPCPD1
uniprot id: A0A2Y9SL77
uniprot id: A0A2Y9SRR8
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

9755:CTNNA1
gene id: 9755:CTNNA1
uniprot id: A0A2Y9EUK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction

9755:DHRS7C
gene id: 9755:DHRS7C
uniprot id: A0A2Y9EKS8
uniprot id: A0A455C040
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9755:LOC102992781
gene id: 9755:LOC102992781
uniprot id: A0A2Y9F3P5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9755:SEPTIN8
gene id: 9755:SEPTIN8
uniprot id: A0A2Y9SFY7
uniprot id: A0A455BZ29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

9755:TMEM182
gene id: 9755:TMEM182
uniprot id: A0A2Y9S831
uniprot id: A0A455BUF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM182 family.
messages: Cell membrane
messages: Membrane

9755:CKS2
gene id: 9755:CKS2
uniprot id: A0A2Y9T8M6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
messages: Forms a homohexamer that can probably bind six kinase subunits.

9755:FAM221B
gene id: 9755:FAM221B
uniprot id: A0A2Y9ETB5
names: Similarity
messages: Belongs to the FAM221 family.

9755:B4GALT2
gene id: 9755:B4GALT2
uniprot id: A0A2Y9STF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

9755:SLC1A3
gene id: 9755:SLC1A3
uniprot id: A0A2Y9EIW5
uniprot id: A0A2Y9EKC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

9755:CLIP1
gene id: 9755:CLIP1
uniprot id: A0A2Y9FTK8
names: Subcellular Location Annotation
messages: cytoskeleton

9755:YIPF6
gene id: 9755:YIPF6
uniprot id: A0A2Y9FD78
uniprot id: A0A2Y9S4M6
uniprot id: A0A455AQY1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:FBLN2
gene id: 9755:FBLN2
uniprot id: A0A2Y9SUT3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fibulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9755:TMEM230
gene id: 9755:TMEM230
uniprot id: A0A2Y9F472
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Early endosome
messages: Endosome
messages: Involved in trafficking and recycling of synaptic vesicles.
messages: Late endosome
messages: Membrane
messages: Recycling endosome
messages: autophagosome
messages: synaptic vesicle
messages: trans-Golgi network

9755:EPC2
gene id: 9755:EPC2
uniprot id: A0A2Y9FA48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enhancer of polycomb family.
messages: Nucleus

9755:TMOD4
gene id: 9755:TMOD4
uniprot id: A0A2Y9FU02
uniprot id: A0A455B9J9
names: Subcellular Location Annotation
messages: cytoskeleton

9755:PAQR5
gene id: 9755:PAQR5
uniprot id: A0A2Y9FDW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

9755:HOXB5
gene id: 9755:HOXB5
uniprot id: A0A2Y9EVV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

9755:PARVA
gene id: 9755:PARVA
uniprot id: A0A2Y9SC18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parvin family.
messages: Cell membrane

9755:GTF2F2
gene id: 9755:GTF2F2
uniprot id: A0A2Y9SWL3
uniprot id: A0A2Y9SYX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB.

9755:FOXJ1
gene id: 9755:FOXJ1
uniprot id: A0A2Y9ECW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FOXJ1 family.
messages: Nucleus

9755:ABCB10
gene id: 9755:ABCB10
uniprot id: A0A2Y9SBZ4
uniprot id: A0A455ALH6
names: Subcellular Location Annotation
messages: Membrane

9755:STAG2
gene id: 9755:STAG2
uniprot id: A0A2Y9EY35
uniprot id: A0A2Y9EYL1
uniprot id: A0A455APH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

9755:LOC102994025
gene id: 9755:LOC102994025
uniprot id: A0A455BWM1
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

9755:DLGAP3
gene id: 9755:DLGAP3
uniprot id: A0A2Y9SRL2
names: Similarity
messages: Belongs to the SAPAP family.

9755:ARRDC1
gene id: 9755:ARRDC1
uniprot id: A0A2Y9SUI8
uniprot id: A0A2Y9SWV5
uniprot id: A0A2Y9SZ62
uniprot id: A0A455BXY8
uniprot id: A0A455C0U1
names: Similarity
messages: Belongs to the arrestin family.

9755:CD28
gene id: 9755:CD28
uniprot id: A0A2Y9F234
names: Subcellular Location Annotation
messages: Membrane

9755:PDYN
gene id: 9755:PDYN
uniprot id: A0A2Y9F6N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A(1-13) has a typical opioid activity, it is 700 times more potent than Leu-enkephalin.
messages: Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress.
messages: Leumorphin has a typical opioid activity and may have anti-apoptotic effect.
messages: Secreted

9755:ARFGEF2
gene id: 9755:ARFGEF2
uniprot id: A0A2Y9T5J1
names: Subcellular Location Annotation
messages: Golgi apparatus
messages: perinuclear region

9755:LOC102976581
gene id: 9755:LOC102976581
uniprot id: A0A2Y9TEH6
uniprot id: A0A455BV73
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

9755:CAPN8
gene id: 9755:CAPN8
uniprot id: A0A2Y9T9G8
names: Caution
names: Similarity
messages: Belongs to the peptidase C2 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:OAZ2
gene id: 9755:OAZ2
uniprot id: A0A2Y9D5R1
names: Similarity
messages: Belongs to the ODC antizyme family.

9755:LOC102975620
gene id: 9755:LOC102975620
uniprot id: A0A2Y9ELK4
names: Similarity
messages: Belongs to the PRAME family.

9755:HSF2
gene id: 9755:HSF2
uniprot id: A0A2Y9SIV9
uniprot id: A0A2Y9SLQ8
uniprot id: A0A2Y9SRK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

9755:STEAP2
gene id: 9755:STEAP2
uniprot id: A0A2Y9FAC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

9755:XPO1
gene id: 9755:XPO1
uniprot id: A0A2Y9EU68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm

9755:PAFAH1B1
gene id: 9755:PAFAH1B1
uniprot id: A0A2Y9FLM5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LIS1/nudF family.
messages: Can self-associate. Interacts with DCX, dynein, dynactin, IQGAP1, KATNB1, NDE1, NDEL1, NUDC and RSN. Interacts with DISC1, and this interaction is enhanced by NDEL1. Interacts with DAB1 when DAB1 is phosphorylated in response to RELN/reelin signaling. Component of cytosolic PAF-AH IB, which is composed of PAFAH1B1 (alpha), PAFAH1B2 (beta) and PAFAH1B3 (gamma) subunits. Trimer formation is not essential for the catalytic activity of the enzyme which is contributed solely by the PAFAH1B2 (beta) and PAFAH1B3 (gamma) subunits.
messages: Dimerization mediated by the LisH domain may be required to activate dynein.
messages: Nucleus membrane
messages: Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate. Neuronal migration involves a process called nucleokinesis, whereby migrating cells extend an anterior process into which the nucleus subsequently translocates. During nucleokinesis dynein at the nuclear surface may translocate the nucleus towards the centrosome by exerting force on centrosomal microtubules. Also required for proper activation of Rho GTPases and actin polymerization at the leading edge of locomoting cerebellar neurons and postmigratory hippocampal neurons in response to calcium influx triggered via NMDA receptors. May also play a role in other forms of cell locomotion including the migration of fibroblasts during wound healing. Non-catalytic subunit of an acetylhydrolase complex which inactivates platelet-activating factor (PAF) by removing the acetyl group at the SN-2 position.
messages: centrosome
messages: cytoskeleton
messages: spindle

9755:ZYG11B
gene id: 9755:ZYG11B
uniprot id: A0A2Y9EVM5
uniprot id: A0A455B942
names: Similarity
messages: Belongs to the zyg-11 family.

9755:TNFAIP6
gene id: 9755:TNFAIP6
uniprot id: A0A2Y9F3F7
uniprot id: A0A2Y9F560
uniprot id: A0A455ABY7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:NECAP2
gene id: 9755:NECAP2
uniprot id: A0A2Y9ST51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

9755:UNC13C
gene id: 9755:UNC13C
uniprot id: A0A2Y9T137
names: Subcellular Location Annotation
messages: Cytoplasm

9755:TSPAN33
gene id: 9755:TSPAN33
uniprot id: A0A2Y9T753
uniprot id: A0A455BA64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9755:STYXL2
gene id: 9755:STYXL2
uniprot id: A0A455B6B1
uniprot id: A0A455B769
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

9755:NID1
gene id: 9755:NID1
uniprot id: A0A455AMP9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

9755:WNT6
gene id: 9755:WNT6
uniprot id: A0A455C8F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9755:KHSRP
gene id: 9755:KHSRP
uniprot id: A0A2Y9TGM4
uniprot id: A0A2Y9TKX1
uniprot id: A0A455C7F5
names: Subcellular Location Annotation
messages: Nucleus

9755:OXT
gene id: 9755:OXT
uniprot id: A0A2Y9SAV1
names: Similarity
messages: Belongs to the vasopressin/oxytocin family.

9755:IL13RA2
gene id: 9755:IL13RA2
uniprot id: A0A2Y9EVA6
names: Subcellular Location Annotation
messages: Membrane

9755:SLC34A3
gene id: 9755:SLC34A3
uniprot id: A0A2Y9T164
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Membrane

9755:APIP
gene id: 9755:APIP
uniprot id: A0A2Y9S842
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aldolase class II family. Adducin subfamily.
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death.
messages: Cytoplasm
messages: Homotetramer. Interacts with APAF1. May interact with CASP1.

9755:KCTD3
gene id: 9755:KCTD3
uniprot id: A0A2Y9T643
names: Similarity
messages: Belongs to the KCTD3 family.

9755:THEMIS2
gene id: 9755:THEMIS2
uniprot id: A0A2Y9FDT1
uniprot id: A0A2Y9ST97
names: Similarity
messages: Belongs to the themis family.

9755:NCDN
gene id: 9755:NCDN
uniprot id: A0A2Y9FG99
uniprot id: A0A455B0C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurochondrin family.
messages: Postsynapse

9755:TPX2
gene id: 9755:TPX2
uniprot id: A0A2Y9FIV1
uniprot id: A0A455BZM0
uniprot id: A0A455C0P9
uniprot id: A0A455CAE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPX2 family.
messages: Nucleus
messages: spindle pole

9755:CDK15
gene id: 9755:CDK15
uniprot id: A0A2Y9ELD7
names: Similarity
messages: Belongs to the protein kinase superfamily.

9755:DBX2
gene id: 9755:DBX2
uniprot id: A0A2Y9F701
names: Subcellular Location Annotation
messages: Nucleus

9755:TBX20
gene id: 9755:TBX20
uniprot id: A0A2Y9FRV6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9755:SGMS1
gene id: 9755:SGMS1
uniprot id: A0A2Y9SE26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

9755:MED28
gene id: 9755:MED28
uniprot id: A0A2Y9EHN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 28 family.
messages: Nucleus

9755:SLC22A12
gene id: 9755:SLC22A12
uniprot id: A0A2Y9TE90
names: Subcellular Location Annotation
messages: Membrane

9755:ARL8B
gene id: 9755:ARL8B
uniprot id: A0A455ASS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: spindle

9755:GNB5
gene id: 9755:GNB5
uniprot id: A0A2Y9FJQ2
uniprot id: A0A2Y9T538
uniprot id: A0A455BVD4
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

9755:GINS1
gene id: 9755:GINS1
uniprot id: A0A2Y9SL95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS1/PSF1 family.
messages: Chromosome
messages: Component of the GINS complex which is a heterotetramer of GINS1, GINS2, GINS3 and GINS4. Forms a stable subcomplex with GINS4. GINS complex interacts with DNA primase in vitro. Component of the CMG helicase complex, a hexameric ring of related MCM2-7 subunits stabilized by CDC45 and the tetrameric GINS complex.
messages: Nucleus
messages: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.

9755:NAGK
gene id: 9755:NAGK
uniprot id: A0A2Y9TI81
names: Similarity
messages: Belongs to the eukaryotic-type N-acetylglucosamine kinase family.

9755:CDH18
gene id: 9755:CDH18
uniprot id: A0A2Y9SDY5
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

9755:HCFC2
gene id: 9755:HCFC2
uniprot id: A0A2Y9FEG0
uniprot id: A0A455BBG3
uniprot id: A0A455BC36
uniprot id: A0A455BC79
uniprot id: A0A455BC84
uniprot id: A0A455BEH4
uniprot id: A0A455BR12
names: Subcellular Location Annotation
messages: Nucleus

9755:ACTR2
gene id: 9755:ACTR2
uniprot id: A0A2Y9FJF5
uniprot id: A0A455BU37
names: Similarity
messages: Belongs to the actin family.

9755:SLC35E4
gene id: 9755:SLC35E4
uniprot id: A0A2Y9FQW3
names: Subcellular Location Annotation
messages: Membrane

9755:PGR
gene id: 9755:PGR
uniprot id: A0A2Y9S4K4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Cytoplasm
messages: Nucleus
messages: Steroid hormone receptor involved in the regulation of eukaryotic gene expression which affects cellular proliferation and differentiation in target tissues.

9755:TLR10
gene id: 9755:TLR10
uniprot id: A0A2Y9EIN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

9755:ADAMTS19
gene id: 9755:ADAMTS19
uniprot id: A0A2Y9SRN0
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9755:TAF11
gene id: 9755:TAF11
uniprot id: A0A2Y9EP04
uniprot id: A0A455AFK1
names: Similarity
messages: Belongs to the TAF11 family.

9755:TIGD6
gene id: 9755:TIGD6
uniprot id: A0A2Y9FY04
names: Subcellular Location Annotation
messages: Nucleus

9755:OXCT1
gene id: 9755:OXCT1
uniprot id: A0A2Y9S8P6
uniprot id: A0A455BXZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
messages: Mitochondrion

9755:C8H5orf24
gene id: 9755:C8H5orf24
uniprot id: A0A2Y9EQM1
uniprot id: A0A2Y9ERY3
names: Similarity
messages: Belongs to the UPF0461 family.

9755:WNT3A
gene id: 9755:WNT3A
uniprot id: A0A2Y9F2M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9755:NDFIP1
gene id: 9755:NDFIP1
uniprot id: A0A2Y9SL53
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

9755:SLC16A9
gene id: 9755:SLC16A9
uniprot id: A0A2Y9EYK3
uniprot id: A0A2Y9F031
uniprot id: A0A2Y9RYE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cell membrane
messages: Membrane

9755:LOC102992942
gene id: 9755:LOC102992942
uniprot id: A0A2Y9ETU4
names: Similarity
messages: Belongs to the MHC class II family.

9755:PERP
gene id: 9755:PERP
uniprot id: A0A2Y9FD91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

9755:LOC112062230
gene id: 9755:LOC112062230
uniprot id: A0A2Y9RZZ3
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9755:GLIS1
gene id: 9755:GLIS1
uniprot id: A0A2Y9FPU1
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

9755:GPR180
gene id: 9755:GPR180
uniprot id: A0A2Y9EFS7
uniprot id: A0A2Y9EGF8
names: Subcellular Location Annotation
messages: Membrane

9755:TMEM17
gene id: 9755:TMEM17
uniprot id: A0A2Y9EQ02
names: Subcellular Location Annotation
messages: Membrane

9755:TNFSF13B
gene id: 9755:TNFSF13B
uniprot id: A0A2Y9SJX1
names: Similarity
messages: Belongs to the tumor necrosis factor family.

9755:DUXB
gene id: 9755:DUXB
uniprot id: A0A2Y9SWJ0
names: Subcellular Location Annotation
messages: Nucleus

9755:LOC102994122
gene id: 9755:LOC102994122
uniprot id: A0A2Y9TKL5
names: Subcellular Location Annotation
messages: Membrane

9755:ZEB1
gene id: 9755:ZEB1
uniprot id: A0A2Y9S0L0
uniprot id: A0A2Y9S451
uniprot id: A0A455BSW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.
messages: Nucleus

9755:TLE3
gene id: 9755:TLE3
uniprot id: A0A455BQ91
names: Similarity
messages: Belongs to the WD repeat Groucho/TLE family.

9755:PAX5
gene id: 9755:PAX5
uniprot id: A0A2Y9FP06
names: Subcellular Location Annotation
messages: Nucleus

9755:CACNB4
gene id: 9755:CACNB4
uniprot id: A0A2Y9ETD2
uniprot id: A0A2Y9EU38
names: Similarity
messages: Belongs to the calcium channel beta subunit family.

9755:ZP4
gene id: 9755:ZP4
uniprot id: A0A2Y9EZV1
uniprot id: A0A2Y9RYE1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPB subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Zona pellucida

9755:ADCY5
gene id: 9755:ADCY5
uniprot id: A0A2Y9EQC1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

9755:DOK6
gene id: 9755:DOK6
uniprot id: A0A2Y9THJ1
names: Similarity
messages: Belongs to the DOK family. Type B subfamily.

9755:AQP6
gene id: 9755:AQP6
uniprot id: A0A2Y9ER55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

9755:ZPBP2
gene id: 9755:ZPBP2
uniprot id: A0A2Y9F094
uniprot id: A0A455C0Q5
uniprot id: A0A455CAM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the zona pellucida-binding protein Sp38 family.
messages: Secreted
messages: acrosome

9755:GPR83
gene id: 9755:GPR83
uniprot id: A0A2Y9F1R5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9755:CUL4A
gene id: 9755:CUL4A
uniprot id: A0A2Y9F8K1
uniprot id: A0A2Y9S3U7
names: Similarity
messages: Belongs to the cullin family.

9755:SERPINE2
gene id: 9755:SERPINE2
uniprot id: A0A2Y9SNS5
names: Similarity
messages: Belongs to the serpin family.

9755:MLLT1
gene id: 9755:MLLT1
uniprot id: A0A2Y9TGS4
uniprot id: A0A2Y9TKZ6
names: Subcellular Location Annotation
messages: Nucleus

9755:SUPT20HL2
gene id: 9755:SUPT20HL2
uniprot id: A0A2Y9S4C1
names: Similarity
messages: Belongs to the SPT20 family.

9755:LHFPL4
gene id: 9755:LHFPL4
uniprot id: A0A2Y9FFY2
names: Subcellular Location Annotation
messages: Membrane

9755:GJB7
gene id: 9755:GJB7
uniprot id: A0A2Y9S1W6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9755:GPC1
gene id: 9755:GPC1
uniprot id: A0A455ATH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

9755:PLA2G2F
gene id: 9755:PLA2G2F
uniprot id: A0A2Y9SUP4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

9755:LOC102986432
gene id: 9755:LOC102986432
uniprot id: A0A2Y9TKP0
names: Similarity
messages: Belongs to the serpin family.

9755:LMNB1
gene id: 9755:LMNB1
uniprot id: A0A2Y9SDA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intermediate filament family.
messages: Nucleus lamina

9755:SUMO2
gene id: 9755:SUMO2
uniprot id: A0A2Y9ECB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

9755:ST18
gene id: 9755:ST18
uniprot id: A0A2Y9SVW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYT1 family.
messages: Nucleus

9755:LOC102975028
gene id: 9755:LOC102975028
uniprot id: A0A455BXQ6
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

9755:LOC102983686
gene id: 9755:LOC102983686
uniprot id: A0A2Y9FUM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

9755:WNT10A
gene id: 9755:WNT10A
uniprot id: A0A2Y9FA17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9755:TCAF2
gene id: 9755:TCAF2
uniprot id: A0A2Y9FD39
names: Similarity
messages: Belongs to the TCAF family.

9755:RETREG3
gene id: 9755:RETREG3
uniprot id: A0A2Y9EI43
uniprot id: A0A455C1R3
uniprot id: A0A455CAM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RETREG family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:MAD1L1
gene id: 9755:MAD1L1
uniprot id: A0A2Y9SRD7
names: Similarity
messages: Belongs to the MAD1 family.

9755:NEMP2
gene id: 9755:NEMP2
uniprot id: A0A2Y9EKA9
uniprot id: A0A2Y9EKX1
uniprot id: A0A2Y9ELE4
uniprot id: A0A2Y9EME9
uniprot id: A0A455AJH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NEMP family.
messages: Nucleus inner membrane

9755:TRAM1L1
gene id: 9755:TRAM1L1
uniprot id: A0A2Y9EX50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

9755:FYTTD1
gene id: 9755:FYTTD1
uniprot id: A0A2Y9SWD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UIF family.
messages: Nucleus speckle
messages: nucleoplasm

9755:ZIC5
gene id: 9755:ZIC5
uniprot id: A0A2Y9SRF4
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

9755:SIDT1
gene id: 9755:SIDT1
uniprot id: A0A2Y9F1U7
uniprot id: A0A2Y9SBJ4
uniprot id: A0A2Y9SBJ9
uniprot id: A0A2Y9SFD5
uniprot id: A0A2Y9SI95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SID1 family.
messages: Membrane

9755:TIRAP
gene id: 9755:TIRAP
uniprot id: A0A2Y9TBL9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Adapter involved in the TLR2 and TLR4 signaling pathways in the innate immune response.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer.
messages: Membrane

9755:LOC112064342
gene id: 9755:LOC112064342
uniprot id: A0A2Y9SGZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

9755:FAM110B
gene id: 9755:FAM110B
uniprot id: A0A455C545
names: Similarity
messages: Belongs to the FAM110 family.

9755:GABBR1
gene id: 9755:GABBR1
uniprot id: A0A2Y9SGN8
uniprot id: A0A455AEY0
uniprot id: A0A455AHB8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:FAM163A
gene id: 9755:FAM163A
uniprot id: A0A2Y9ELA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

9755:CCNQ
gene id: 9755:CCNQ
uniprot id: A0A2Y9S1W0
uniprot id: A0A455APV7
names: Similarity
messages: Belongs to the cyclin family. Cyclin-like FAM58 subfamily.

9755:CCL17
gene id: 9755:CCL17
uniprot id: A0A2Y9FSA2
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.

9755:RPL4
gene id: 9755:RPL4
uniprot id: A0A2Y9FP87
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

9755:NEK7
gene id: 9755:NEK7
uniprot id: A0A455B566
uniprot id: A0A455B5K0
uniprot id: A0A455B5L0
uniprot id: A0A455B7W7
names: Similarity
messages: Belongs to the protein kinase superfamily.

9755:FBP2
gene id: 9755:FBP2
uniprot id: A0A2Y9FFZ3
names: Similarity
messages: Belongs to the FBPase class 1 family.

9755:LOC112062401
gene id: 9755:LOC112062401
uniprot id: A0A2Y9F8A0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9755:SLC30A9
gene id: 9755:SLC30A9
uniprot id: A0A2Y9FJX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Endoplasmic reticulum
messages: Membrane
messages: Mitochondrion membrane
messages: Nucleus

9755:DOK5
gene id: 9755:DOK5
uniprot id: A0A2Y9F1Q2
names: Similarity
messages: Belongs to the DOK family. Type B subfamily.

9755:LOC112064619
gene id: 9755:LOC112064619
uniprot id: A0A2Y9SHS0
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

9755:CPO
gene id: 9755:CPO
uniprot id: A0A2Y9FJQ8
names: Similarity
messages: Belongs to the peptidase M14 family.

9755:NKAIN4
gene id: 9755:NKAIN4
uniprot id: A0A2Y9T0H7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:RBM10
gene id: 9755:RBM10
uniprot id: A0A2Y9ELV5
uniprot id: A0A455AP92
uniprot id: A0A455API2
uniprot id: A0A455AQW7
uniprot id: A0A455ARD6
uniprot id: A0A455B368
names: Subcellular Location Annotation
messages: Nucleus

9755:KIF1B
gene id: 9755:KIF1B
uniprot id: A0A455B3Y7
uniprot id: A0A455B3Z3
uniprot id: A0A455B4C8
uniprot id: A0A455B6L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: axon

9755:CENPA
gene id: 9755:CENPA
uniprot id: A0A2Y9ET18
uniprot id: A0A2Y9EUC7
names: Similarity
messages: Belongs to the histone H3 family.

9755:LOC102990258
gene id: 9755:LOC102990258
uniprot id: A0A455B0W8
names: Similarity
messages: Belongs to the cytochrome P450 family.

9755:UROS
gene id: 9755:UROS
uniprot id: A0A2Y9SIH4
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.

9755:ACAT1
gene id: 9755:ACAT1
uniprot id: A0A2Y9EZ35
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

9755:LOC102982999
gene id: 9755:LOC102982999
uniprot id: A0A2Y9F9A8
uniprot id: A0A2Y9F9J3
uniprot id: A0A2Y9FBD1
uniprot id: A0A455AI35
names: Similarity
messages: Belongs to the cytochrome P450 family.

9755:ST8SIA6
gene id: 9755:ST8SIA6
uniprot id: A0A2Y9S471
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9755:TRPC4
gene id: 9755:TRPC4
uniprot id: A0A2Y9F7Z7
uniprot id: A0A2Y9F885
uniprot id: A0A2Y9F8P0
uniprot id: A0A2Y9F9X8
uniprot id: A0A2Y9F9Y3
names: Subcellular Location Annotation
messages: Membrane

9755:GBX1
gene id: 9755:GBX1
uniprot id: A0A455BDU6
names: Subcellular Location Annotation
messages: Nucleus

9755:BEGAIN
gene id: 9755:BEGAIN
uniprot id: A0A2Y9T9B6
names: Subcellular Location Annotation
messages: Membrane

9755:MRPS10
gene id: 9755:MRPS10
uniprot id: A0A2Y9FDJ3
uniprot id: A0A2Y9FFG0
uniprot id: A0A2Y9SJU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Mitochondrion

9755:SLC29A1
gene id: 9755:SLC29A1
uniprot id: A0A455AGK4
uniprot id: A0A455AH30
uniprot id: A0A455AUP4
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Basolateral cell membrane
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Lateral cell membrane
messages: Membrane

9755:WARS2
gene id: 9755:WARS2
uniprot id: A0A2Y9FIR0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9755:LOC102992931
gene id: 9755:LOC102992931
uniprot id: A0A455B5J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

9755:PDE6B
gene id: 9755:PDE6B
uniprot id: A0A2Y9F445
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9755:LOC102992041
gene id: 9755:LOC102992041
uniprot id: A0A2Y9EZ65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:INO80
gene id: 9755:INO80
uniprot id: A0A2Y9TGT2
uniprot id: A0A2Y9TL44
uniprot id: A0A455BQK5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Component of the INO80 chromatin-remodeling complex.
messages: Nucleus
messages: The DBINO region is involved in binding to DNA.

9755:CLDN17
gene id: 9755:CLDN17
uniprot id: A0A2Y9FPG5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9755:SGCE
gene id: 9755:SGCE
uniprot id: A0A2Y9EMC5
uniprot id: A0A2Y9ENR2
names: Function
names: Similarity
messages: Belongs to the sarcoglycan alpha/epsilon family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.

9755:PSMC2
gene id: 9755:PSMC2
uniprot id: A0A2Y9FS10
names: Similarity
messages: Belongs to the AAA ATPase family.

9755:E2F8
gene id: 9755:E2F8
uniprot id: A0A2Y9S7Z8
uniprot id: A0A2Y9S8J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

9755:COPS5
gene id: 9755:COPS5
uniprot id: A0A2Y9FUL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M67A family. CSN5 subfamily.
messages: synaptic vesicle

9755:DLX4
gene id: 9755:DLX4
uniprot id: A0A2Y9FQE7
uniprot id: A0A455C2Q5
names: Subcellular Location Annotation
messages: Nucleus

9755:TADA2B
gene id: 9755:TADA2B
uniprot id: A0A2Y9SHT4
names: Subcellular Location Annotation
messages: Nucleus

9755:LOC102974513
gene id: 9755:LOC102974513
uniprot id: A0A2Y9F649
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

9755:TMEM38A
gene id: 9755:TMEM38A
uniprot id: A0A455BPQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.
messages: Nucleus

9755:PPIP5K1
gene id: 9755:PPIP5K1
uniprot id: A0A455BQD2
uniprot id: A0A455BQD7
uniprot id: A0A455BQE2
uniprot id: A0A455BQE6
uniprot id: A0A455BQE7
uniprot id: A0A455BQF1
uniprot id: A0A455BQF6
uniprot id: A0A455BQG1
uniprot id: A0A455BR19
uniprot id: A0A455BR25
uniprot id: A0A455BR30
uniprot id: A0A455BR36
uniprot id: A0A455BTP8
uniprot id: A0A455BTQ7
uniprot id: A0A455BTR3
uniprot id: A0A455C5H0
uniprot id: A0A455C5H7
uniprot id: A0A455C5I2
uniprot id: A0A455C5I7
uniprot id: A0A455C5J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytosol

9755:IGF1R
gene id: 9755:IGF1R
uniprot id: A0A2Y9TH39
uniprot id: A0A2Y9TK79
uniprot id: A0A455BPW4
uniprot id: A0A455BPY1
uniprot id: A0A455BQL4
uniprot id: A0A455BT75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

9755:XKR5
gene id: 9755:XKR5
uniprot id: A0A2Y9S5T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

9755:JUP
gene id: 9755:JUP
uniprot id: A0A455C1P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: adherens junction

9755:TMEM176B
gene id: 9755:TMEM176B
uniprot id: A0A2Y9TAU0
names: Similarity
messages: Belongs to the TMEM176 family.

9755:SNX10
gene id: 9755:SNX10
uniprot id: A0A455BN12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

9755:C1R
gene id: 9755:C1R
uniprot id: A0A2Y9T663
uniprot id: A0A455BCS6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:CNNM4
gene id: 9755:CNNM4
uniprot id: A0A2Y9EZJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Cell membrane
messages: Membrane
messages: Metal transporter.

9755:CELSR1
gene id: 9755:CELSR1
uniprot id: A0A2Y9T4A5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor that may have an important role in cell/cell signaling during nervous system formation.

9755:LOC102989062
gene id: 9755:LOC102989062
uniprot id: A0A2Y9ENG1
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Involved in nucleotide metabolism via production of dUMP, the immediate precursor of thymidine nucleotides, and decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

9755:TMEM41B
gene id: 9755:TMEM41B
uniprot id: A0A2Y9FD79
uniprot id: A0A2Y9FD85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM41 family.
messages: Membrane

9755:RPS19
gene id: 9755:RPS19
uniprot id: A0A2Y9EH42
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS19 family.

9755:CD244
gene id: 9755:CD244
uniprot id: A0A2Y9S6G5
names: Subcellular Location Annotation
messages: Membrane

9755:SH2B2
gene id: 9755:SH2B2
uniprot id: A0A2Y9FLS4
uniprot id: A0A2Y9SNT2
names: Similarity
messages: Belongs to the SH2B adapter family.

9755:CAPZA3
gene id: 9755:CAPZA3
uniprot id: A0A2Y9FMN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

9755:LDB2
gene id: 9755:LDB2
uniprot id: A0A2Y9S9E3
uniprot id: A0A2Y9SD60
uniprot id: A0A2Y9SG52
uniprot id: A0A2Y9SHT9
names: Similarity
messages: Belongs to the LDB family.

9755:GCNT4
gene id: 9755:GCNT4
uniprot id: A0A455BJ51
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

9755:SEC23B
gene id: 9755:SEC23B
uniprot id: A0A2Y9F532
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

9755:GCLC
gene id: 9755:GCLC
uniprot id: A0A2Y9SGV1
uniprot id: A0A2Y9SJV1
uniprot id: A0A455AG21
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 3 family.

9755:GDPD4
gene id: 9755:GDPD4
uniprot id: A0A2Y9T8V5
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

9755:ZNF397
gene id: 9755:ZNF397
uniprot id: A0A2Y9FHS3
uniprot id: A0A2Y9SCJ4
names: Subcellular Location Annotation
messages: Nucleus

9755:GC
gene id: 9755:GC
uniprot id: A0A2Y9EXW2
names: Function
names: Subcellular Location Annotation
messages: Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation.
messages: Secreted

9755:LOC102981626
gene id: 9755:LOC102981626
uniprot id: A0A2Y9SVH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:ANAPC2
gene id: 9755:ANAPC2
uniprot id: A0A2Y9EJM4
names: Similarity
messages: Belongs to the cullin family.

9755:HDAC10
gene id: 9755:HDAC10
uniprot id: A0A2Y9FPX6
names: Similarity
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.

9755:PHYHIP
gene id: 9755:PHYHIP
uniprot id: A0A2Y9FP57
names: Similarity
messages: Belongs to the PHYHIP family.

9755:NKX1-1
gene id: 9755:NKX1-1
uniprot id: A0A2Y9SGV0
names: Subcellular Location Annotation
messages: Nucleus

9755:LOC102980197
gene id: 9755:LOC102980197
uniprot id: A0A2Y9F6K6
names: Similarity
messages: Belongs to the NipSnap family.

9755:LOC102981375
gene id: 9755:LOC102981375
uniprot id: A0A2Y9FLJ9
uniprot id: A0A2Y9FN31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

9755:LOC102992241
gene id: 9755:LOC102992241
uniprot id: A0A455C5V3
uniprot id: A0A455C5W0
uniprot id: A0A455C641
uniprot id: A0A455C646
uniprot id: A0A455C6W2
uniprot id: A0A455C928
uniprot id: A0A455CBP8
names: Subcellular Location Annotation
messages: nuclear pore complex

9755:LOC102993638
gene id: 9755:LOC102993638
uniprot id: A0A2Y9FI24
names: Similarity
messages: Belongs to the NKAP family.

9755:GSR
gene id: 9755:GSR
uniprot id: A0A2Y9FBD5
uniprot id: A0A2Y9FBL4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: Maintains high levels of reduced glutathione in the cytosol.

9755:MS4A3
gene id: 9755:MS4A3
uniprot id: A0A2Y9TI01
names: Similarity
messages: Belongs to the MS4A family.

9755:SLC6A1
gene id: 9755:SLC6A1
uniprot id: A0A2Y9F8R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

9755:LCN8
gene id: 9755:LCN8
uniprot id: A0A455C9D5
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

9755:PLAU
gene id: 9755:PLAU
uniprot id: A0A2Y9F590
uniprot id: A0A455AL34
uniprot id: A0A455AZU6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:DPH2
gene id: 9755:DPH2
uniprot id: A0A2Y9EZ49
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family. DPH2 subfamily.
messages: Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase. Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit.

9755:PSMD12
gene id: 9755:PSMD12
uniprot id: A0A455C021
names: Similarity
messages: Belongs to the proteasome subunit p55 family.

9755:LOC102987821
gene id: 9755:LOC102987821
uniprot id: A0A2Y9SW75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

9755:TSHZ1
gene id: 9755:TSHZ1
uniprot id: A0A2Y9TKG6
names: Similarity
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.

9755:LRRC8A
gene id: 9755:LRRC8A
uniprot id: A0A2Y9EJS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

9755:ATPAF2
gene id: 9755:ATPAF2
uniprot id: A0A2Y9SY13
uniprot id: A0A455C2W8
uniprot id: A0A455C7B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

9755:SSR3
gene id: 9755:SSR3
uniprot id: A0A2Y9ESM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-gamma family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

9755:ZWILCH
gene id: 9755:ZWILCH
uniprot id: A0A2Y9FR03
uniprot id: A0A2Y9FRV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZWILCH family.
messages: Component of the RZZ complex.
messages: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex.
messages: kinetochore

9755:PABPC1
gene id: 9755:PABPC1
uniprot id: A0A2Y9ELL8
uniprot id: A0A2Y9ELR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

9755:LOC112063604
gene id: 9755:LOC112063604
uniprot id: A0A2Y9SAR2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

9755:RRP8
gene id: 9755:RRP8
uniprot id: A0A2Y9EJ44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RRP8 family.
messages: Component of the eNoSC complex.
messages: Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase.
messages: nucleolus

9755:THEMIS
gene id: 9755:THEMIS
uniprot id: A0A455BNL4
names: Similarity
messages: Belongs to the themis family.

9755:TOP1MT
gene id: 9755:TOP1MT
uniprot id: A0A2Y9T478
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

9755:POLR2D
gene id: 9755:POLR2D
uniprot id: A0A2Y9RWW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Nucleus

9755:TRMO
gene id: 9755:TRMO
uniprot id: A0A2Y9F5S5
uniprot id: A0A455BL23
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

9755:SRF
gene id: 9755:SRF
uniprot id: A0A2Y9ES03
uniprot id: A0A2Y9ET71
names: Subcellular Location Annotation
messages: Nucleus

9755:USP39
gene id: 9755:USP39
uniprot id: A0A2Y9TA00
names: Subcellular Location Annotation
messages: Nucleus

9755:LOC102984784
gene id: 9755:LOC102984784
uniprot id: A0A2Y9F481
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

9755:NRXN2
gene id: 9755:NRXN2
uniprot id: A0A2Y9TDN2
uniprot id: A0A2Y9TFF4
uniprot id: A0A2Y9TFF9
uniprot id: A0A2Y9TJT1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:LOC102977200
gene id: 9755:LOC102977200
uniprot id: A0A455BYY9
uniprot id: A0A455BYZ7
uniprot id: A0A455CA91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

9755:SLC25A12
gene id: 9755:SLC25A12
uniprot id: A0A2Y9F9R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

9755:DGAT1
gene id: 9755:DGAT1
uniprot id: A0A2Y9SBW3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Homodimer or homotetramer; both forms have similar enzymatic activities.
messages: Membrane

9755:FAM216B
gene id: 9755:FAM216B
uniprot id: A0A2Y9FII5
names: Similarity
messages: Belongs to the FAM216 family.

9755:GALNT4
gene id: 9755:GALNT4
uniprot id: A0A2Y9FHF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9755:LOC112062060
gene id: 9755:LOC112062060
uniprot id: A0A2Y9RY04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

9755:ATP6V1B1
gene id: 9755:ATP6V1B1
uniprot id: A0A2Y9FR60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.

9755:CCNG1
gene id: 9755:CCNG1
uniprot id: A0A2Y9FF13
uniprot id: A0A455BMX4
names: Similarity
messages: Belongs to the cyclin family.

9755:MAN2A2
gene id: 9755:MAN2A2
uniprot id: A0A2Y9ESW6
uniprot id: A0A2Y9ET46
uniprot id: A0A455BPF0
uniprot id: A0A455BPH5
uniprot id: A0A455BQ33
uniprot id: A0A455C4I0
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

9755:MAPK8IP2
gene id: 9755:MAPK8IP2
uniprot id: A0A2Y9T4D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JIP scaffold family.
messages: Cytoplasm

9755:PNN
gene id: 9755:PNN
uniprot id: A0A2Y9F935
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pinin family.
messages: Found in a mRNA splicing-dependent exon junction complex (EJC). Found in a complex with SR proteins. Found in a mRNP complex with RNPS1. Component of the PSAP complex consisting of RNPS1, SAP18 and PNN. Interacts with PNISR, CTBP1, CTBP2, KRT8, KRT18, KRT19, PS1D/PNO40, PPIG, RNPS1, SFRS4 and SRRM2. Identified in the spliceosome C complex.
messages: Nucleus speckle
messages: desmosome

9755:LOC112065457
gene id: 9755:LOC112065457
uniprot id: A0A2Y9SUF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

9755:SRMS
gene id: 9755:SRMS
uniprot id: A0A455CAT8
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

9755:ADAMTS20
gene id: 9755:ADAMTS20
uniprot id: A0A2Y9EQ12
uniprot id: A0A455BE33
uniprot id: A0A455BEN8
uniprot id: A0A455BEQ3
uniprot id: A0A455BEQ7
uniprot id: A0A455BH45
uniprot id: A0A455BH52
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9755:VDAC2
gene id: 9755:VDAC2
uniprot id: A0A2Y9EGH8
names: Similarity
messages: Belongs to the eukaryotic mitochondrial porin family.

9755:LOC102986522
gene id: 9755:LOC102986522
uniprot id: A0A455ARS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H2A family.
messages: Belongs to the histone H3 family.
messages: Chromosome
messages: Nucleus

9755:SLC35B4
gene id: 9755:SLC35B4
uniprot id: A0A2Y9TBT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

9755:GRK4
gene id: 9755:GRK4
uniprot id: A0A455BJZ3
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

9755:LOC102981261
gene id: 9755:LOC102981261
uniprot id: A0A2Y9EGY0
names: Similarity
messages: Belongs to the formin homology family. Diaphanous subfamily.

9755:CER1
gene id: 9755:CER1
uniprot id: A0A2Y9FNM2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9755:PGAM2
gene id: 9755:PGAM2
uniprot id: A0A2Y9F303
uniprot id: A0A2Y9RWG1
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

9755:SPICE1
gene id: 9755:SPICE1
uniprot id: A0A2Y9ESD8
uniprot id: A0A2Y9EU07
uniprot id: A0A2Y9SEZ3
uniprot id: A0A2Y9SJK5
uniprot id: A0A455BK77
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with CEP120.
messages: centriole
messages: spindle

9755:LOC102988625
gene id: 9755:LOC102988625
uniprot id: A0A2Y9FRW5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9755:ACER3
gene id: 9755:ACER3
uniprot id: A0A2Y9T8X2
uniprot id: A0A2Y9TCF1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:AASDH
gene id: 9755:AASDH
uniprot id: A0A2Y9F6X5
uniprot id: A0A2Y9F6Y0
uniprot id: A0A2Y9F7Z5
uniprot id: A0A455BFP8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

9755:LOC102989485
gene id: 9755:LOC102989485
uniprot id: A0A2Y9SDW9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:IQSEC1
gene id: 9755:IQSEC1
uniprot id: A0A455AEF3
uniprot id: A0A455AEV1
uniprot id: A0A455AGU7
uniprot id: A0A455AS95
names: Similarity
messages: Belongs to the BRAG family.

9755:OGFOD1
gene id: 9755:OGFOD1
uniprot id: A0A2Y9EQN3
names: Similarity
messages: Belongs to the TPA1 family.

9755:PIWIL2
gene id: 9755:PIWIL2
uniprot id: A0A2Y9FM67
uniprot id: A0A455BLX4
names: Similarity
messages: Belongs to the argonaute family.

9755:POU5F1
gene id: 9755:POU5F1
uniprot id: A0A2Y9EQM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

9755:LOC102981519
gene id: 9755:LOC102981519
uniprot id: A0A2Y9FBM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha-casein family.
messages: Important role in the capacity of milk to transport calcium phosphate.
messages: Secreted

9755:RDH12
gene id: 9755:RDH12
uniprot id: A0A2Y9FEZ1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9755:PLA2G5
gene id: 9755:PLA2G5
uniprot id: A0A2Y9F1R2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

9755:NPM1
gene id: 9755:NPM1
uniprot id: A0A2Y9FWX8
uniprot id: A0A2Y9RYQ1
names: Similarity
messages: Belongs to the nucleoplasmin family.

9755:ERLIN2
gene id: 9755:ERLIN2
uniprot id: A0A455ALD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the band 7/mec-2 family.
messages: Endoplasmic reticulum membrane
messages: Mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway.
messages: Membrane

9755:TCN1
gene id: 9755:TCN1
uniprot id: A0A2Y9FB10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic cobalamin transport proteins family.
messages: Secreted

9755:SLC25A38
gene id: 9755:SLC25A38
uniprot id: A0A2Y9S957
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
messages: Membrane
messages: Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis.
messages: Mitochondrion inner membrane
messages: Plays a role as pro-apoptotic protein that induces caspase-dependent apoptosis.

9755:TPP1
gene id: 9755:TPP1
uniprot id: A0A2Y9EHQ1
names: Cofactor
messages: Binds 1 Ca(2+) ion per subunit.

9755:LYPLAL1
gene id: 9755:LYPLAL1
uniprot id: A0A455B827
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

9755:PRR5L
gene id: 9755:PRR5L
uniprot id: A0A2Y9EQ59
names: Similarity
messages: Belongs to the PROTOR family.

9755:SAP130
gene id: 9755:SAP130
uniprot id: A0A2Y9FMU4
uniprot id: A0A2Y9FNB9
uniprot id: A0A2Y9FPK1
uniprot id: A0A2Y9RZW9
uniprot id: A0A455C7A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAP130 family.
messages: Nucleus

9755:LOC112066214
gene id: 9755:LOC112066214
uniprot id: A0A2Y9T0H1
names: Similarity
messages: Belongs to the SS18 family.

9755:ATF1
gene id: 9755:ATF1
uniprot id: A0A2Y9SJX7
uniprot id: A0A2Y9SQP7
uniprot id: A0A455BEG6
names: Subcellular Location Annotation
messages: Nucleus

9755:TPM3
gene id: 9755:TPM3
uniprot id: A0A2Y9FTK6
uniprot id: A0A2Y9FVL5
uniprot id: A0A2Y9FWM0
uniprot id: A0A2Y9S7F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

9755:XKR9
gene id: 9755:XKR9
uniprot id: A0A2Y9FTX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

9755:ENSA
gene id: 9755:ENSA
uniprot id: A0A2Y9FIG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.

9755:BRINP2
gene id: 9755:BRINP2
uniprot id: A0A2Y9TIM9
names: Similarity
messages: Belongs to the BRINP family.

9755:EVA1C
gene id: 9755:EVA1C
uniprot id: A0A2Y9EFM1
names: Similarity
messages: Belongs to the EVA1 family.

9755:BET1
gene id: 9755:BET1
uniprot id: A0A2Y9TET0
names: Subcellular Location Annotation
messages: Membrane

9755:SLC28A2
gene id: 9755:SLC28A2
uniprot id: A0A2Y9F7M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

9755:RUNX1T1
gene id: 9755:RUNX1T1
uniprot id: A0A2Y9EYZ2
uniprot id: A0A2Y9EZI6
uniprot id: A0A2Y9F0G7
uniprot id: A0A2Y9RYY0
names: Similarity
messages: Belongs to the CBFA2T family.

9755:PIERCE1
gene id: 9755:PIERCE1
uniprot id: A0A2Y9EH74
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with CFAP53, ODAD1 and ODAD3; the interactions link the outer dynein arms docking complex (ODA-DC) to the internal microtubule inner proteins (MIP) in cilium axoneme.
messages: cilium axoneme

9755:ADGRF1
gene id: 9755:ADGRF1
uniprot id: A0A2Y9SNB2
names: Subcellular Location Annotation
messages: Membrane

9755:XPC
gene id: 9755:XPC
uniprot id: A0A455AGZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPC family.
messages: Nucleus

9755:LOC102996807
gene id: 9755:LOC102996807
uniprot id: A0A2Y9TFL1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:POMK
gene id: 9755:POMK
uniprot id: A0A2Y9TEG1
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N-acetylglucosamine (GlcNAc)-beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-1,3-N-acetylglucosamine-beta-1,4-(phosphate-6-)mannose). Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Only shows kinase activity when the GalNAc-beta-3-GlcNAc-beta-terminus is linked to the 4-position of O-mannose, suggesting that this disaccharide serves as the substrate recognition motif.

9755:MTX3
gene id: 9755:MTX3
uniprot id: A0A2Y9FJ33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

9755:HOXA1
gene id: 9755:HOXA1
uniprot id: A0A2Y9F1W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family. Labial subfamily.
messages: Nucleus

9755:LOC102992571
gene id: 9755:LOC102992571
uniprot id: A0A2Y9FSW6
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

9755:SPPL2A
gene id: 9755:SPPL2A
uniprot id: A0A2Y9RZN7
uniprot id: A0A2Y9S370
uniprot id: A0A455C5A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Endosome membrane
messages: Lysosome membrane
messages: Membrane

9755:PHF10
gene id: 9755:PHF10
uniprot id: A0A2Y9SI64
uniprot id: A0A2Y9SLN9
uniprot id: A0A2Y9SPP9
uniprot id: A0A455BRU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAYP family.
messages: Nucleus

9755:GABRA5
gene id: 9755:GABRA5
uniprot id: A0A2Y9RWR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9755:WNK3
gene id: 9755:WNK3
uniprot id: A0A2Y9T1E8
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

9755:CYFIP2
gene id: 9755:CYFIP2
uniprot id: A0A2Y9S366
names: Similarity
messages: Belongs to the CYFIP family.

9755:BECN2
gene id: 9755:BECN2
uniprot id: A0A2Y9ESN3
names: Similarity
messages: Belongs to the beclin family.

9755:TEAD1
gene id: 9755:TEAD1
uniprot id: A0A455C5Z8
names: Subcellular Location Annotation
messages: Nucleus

9755:LOC102978064
gene id: 9755:LOC102978064
uniprot id: A0A2Y9TIF3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:BTAF1
gene id: 9755:BTAF1
uniprot id: A0A2Y9SKZ0
uniprot id: A0A2Y9SMQ4
names: Subcellular Location Annotation
messages: Nucleus

9755:NUP205
gene id: 9755:NUP205
uniprot id: A0A2Y9FAS5
uniprot id: A0A2Y9FCR2
names: Similarity
messages: Belongs to the NUP186/NUP192/NUP205 family.

9755:LOC112065747
gene id: 9755:LOC112065747
uniprot id: A0A2Y9T0Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

9755:PKD2
gene id: 9755:PKD2
uniprot id: A0A2Y9SUI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Cell membrane
messages: Membrane
messages: cilium membrane

9755:WDR4
gene id: 9755:WDR4
uniprot id: A0A2Y9EXZ7
uniprot id: A0A2Y9EY16
uniprot id: A0A2Y9F023
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat TRM82 family.
messages: Nucleus
messages: Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

9755:ADAM17
gene id: 9755:ADAM17
uniprot id: A0A2Y9FNR2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:LOC102987095
gene id: 9755:LOC102987095
uniprot id: A0A455BXU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9755:CLDN2
gene id: 9755:CLDN2
uniprot id: A0A2Y9F2L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9755:LOC102982813
gene id: 9755:LOC102982813
uniprot id: A0A455BKZ2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:GPR15
gene id: 9755:GPR15
uniprot id: A0A2Y9F5Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9755:RPL27A
gene id: 9755:RPL27A
uniprot id: A0A2Y9EMF7
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

9755:SMPDL3A
gene id: 9755:SMPDL3A
uniprot id: A0A2Y9F9B9
uniprot id: A0A2Y9F9X0
uniprot id: A0A455BMT2
uniprot id: A0A455BNH2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) per subunit.
messages: Secreted

9755:APOC3
gene id: 9755:APOC3
uniprot id: A0A2Y9F8Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apolipoprotein C3 family.
messages: Secreted

9755:GNG12
gene id: 9755:GNG12
uniprot id: A0A2Y9SAY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

9755:HTR6
gene id: 9755:HTR6
uniprot id: A0A2Y9EMI5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9755:LOC112067420
gene id: 9755:LOC112067420
uniprot id: A0A2Y9TF27
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:CAMK2G
gene id: 9755:CAMK2G
uniprot id: A0A2Y9TC49
uniprot id: A0A2Y9TE06
uniprot id: A0A2Y9TE12
uniprot id: A0A2Y9TG39
uniprot id: A0A2Y9TG44
uniprot id: A0A455AJV6
uniprot id: A0A455AJV9
uniprot id: A0A455AK44
uniprot id: A0A455AK48
uniprot id: A0A455ALM3
uniprot id: A0A455ALM9
uniprot id: A0A455ALN4
uniprot id: A0A455ALR0
uniprot id: A0A455AYD4
uniprot id: A0A455AYD9
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

9755:DCT
gene id: 9755:DCT
uniprot id: A0A2Y9EH20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

9755:PLAC8L1
gene id: 9755:PLAC8L1
uniprot id: A0A2Y9SQP0
names: Similarity
messages: Belongs to the cornifelin family.

9755:LOC112066660
gene id: 9755:LOC112066660
uniprot id: A0A2Y9T9D4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space
messages: Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

9755:RALY
gene id: 9755:RALY
uniprot id: A0A2Y9T3V0
uniprot id: A0A455BZB4
uniprot id: A0A455BZB8
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

9755:DCLK1
gene id: 9755:DCLK1
uniprot id: A0A2Y9SYI9
uniprot id: A0A455BYE2
uniprot id: A0A455C9Y5
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

9755:NFKB2
gene id: 9755:NFKB2
uniprot id: A0A2Y9FMN6
uniprot id: A0A2Y9FN08
uniprot id: A0A455AN60
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9755:FGD6
gene id: 9755:FGD6
uniprot id: A0A2Y9FKU7
uniprot id: A0A455BEB4
names: Subcellular Location Annotation
messages: cytoskeleton

9755:TMEM184C
gene id: 9755:TMEM184C
uniprot id: A0A2Y9SWD3
names: Subcellular Location Annotation
messages: Membrane

9755:TMEM176A
gene id: 9755:TMEM176A
uniprot id: A0A2Y9FM63
uniprot id: A0A2Y9FNS6
names: Similarity
messages: Belongs to the TMEM176 family.

9755:ADCK1
gene id: 9755:ADCK1
uniprot id: A0A455BSR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.
messages: Secreted

9755:EIF2AK3
gene id: 9755:EIF2AK3
uniprot id: A0A2Y9T9Q8
uniprot id: A0A455BVD5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

9755:GPR18
gene id: 9755:GPR18
uniprot id: A0A455BVP7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9755:RNASE1
gene id: 9755:RNASE1
uniprot id: A0A2Y9FPD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

9755:POP5
gene id: 9755:POP5
uniprot id: A0A2Y9FT40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
messages: nucleolus

9755:TUBB2A
gene id: 9755:TUBB2A
uniprot id: A0A2Y9SFJ7
uniprot id: A0A2Y9SM60
uniprot id: A0A455ADW0
uniprot id: A0A455AR70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

9755:LOC102982230
gene id: 9755:LOC102982230
uniprot id: A0A2Y9SL79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC7 family.
messages: Nucleus
messages: Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.

9755:OPRK1
gene id: 9755:OPRK1
uniprot id: A0A2Y9T3X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain. Plays a role in mediating reduced physical activity upon treatment with synthetic opioids. Plays a role in the regulation of salivation in response to synthetic opioids. May play a role in arousal and regulation of autonomic and neuroendocrine functions.
messages: Interacts with NHERF1. Interacts with GABARAPL1.
messages: Membrane

9755:FNTB
gene id: 9755:FNTB
uniprot id: A0A2Y9S6P6
uniprot id: A0A2Y9SD26
uniprot id: A0A2Y9SEJ5
uniprot id: A0A455BS48
uniprot id: A0A455BS57
uniprot id: A0A455BSU0
uniprot id: A0A455BVI1
uniprot id: A0A455C7A2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.
messages: Heterodimer of FNTA and FNTB.

9755:AGRP
gene id: 9755:AGRP
uniprot id: A0A2Y9FKZ2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9755:PPFIBP1
gene id: 9755:PPFIBP1
uniprot id: A0A2Y9T5J7
uniprot id: A0A455BD75
uniprot id: A0A455BD79
uniprot id: A0A455BD84
uniprot id: A0A455BDW5
uniprot id: A0A455BG94
uniprot id: A0A455BG99
uniprot id: A0A455BSV3
uniprot id: A0A455BSV8
uniprot id: A0A455BSW3
names: Similarity
messages: Belongs to the liprin family. Liprin-beta subfamily.

9755:ATP11B
gene id: 9755:ATP11B
uniprot id: A0A2Y9SP99
uniprot id: A0A2Y9SRS2
uniprot id: A0A2Y9SUG6
uniprot id: A0A455BEX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

9755:LOC102995131
gene id: 9755:LOC102995131
uniprot id: A0A455C5S9
names: Similarity
messages: Belongs to the ODC antizyme family.

9755:LOC112062610
gene id: 9755:LOC112062610
uniprot id: A0A2Y9S3W0
names: Similarity
messages: Belongs to the FAM83 family.

9755:SLC6A8
gene id: 9755:SLC6A8
uniprot id: A0A2Y9S1U4
uniprot id: A0A455AMU6
uniprot id: A0A455API6
uniprot id: A0A455B1M4
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A8 subfamily.
messages: Cell membrane
messages: Membrane

9755:IFRD1
gene id: 9755:IFRD1
uniprot id: A0A2Y9T2Y4
uniprot id: A0A455BCI0
names: Similarity
messages: Belongs to the IFRD family.

9755:AK6
gene id: 9755:AK6
uniprot id: A0A2Y9FW02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation.
messages: Cajal body
messages: Monomer and homodimer. Interacts with COIL (via C-terminus).
messages: nucleoplasm

9755:LOC112065329
gene id: 9755:LOC112065329
uniprot id: A0A2Y9T051
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the REI1 family.
messages: Cytoplasm

9755:CDC42SE1
gene id: 9755:CDC42SE1
uniprot id: A0A2Y9FTZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Interacts with CDC42 (in GTP-bound form). Interacts weakly with RAC1 and not at all with RHOA.
messages: Membrane
messages: Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages.
messages: cytoskeleton

9755:SPARCL1
gene id: 9755:SPARCL1
uniprot id: A0A2Y9ETV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPARC family.
messages: extracellular matrix

9755:PKD1L1
gene id: 9755:PKD1L1
uniprot id: A0A455B8G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Membrane

9755:FOXC1
gene id: 9755:FOXC1
uniprot id: A0A2Y9SH56
names: Subcellular Location Annotation
messages: Nucleus

9755:WNT5A
gene id: 9755:WNT5A
uniprot id: A0A2Y9SMX4
uniprot id: A0A2Y9ST80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9755:BORCS7
gene id: 9755:BORCS7
uniprot id: A0A2Y9FN27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS7 family.
messages: Lysosome membrane
messages: Membrane

9755:ALDH9A1
gene id: 9755:ALDH9A1
uniprot id: A0A2Y9FR82
uniprot id: A0A2Y9FRC6
uniprot id: A0A2Y9FTY2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

9755:LOC102978444
gene id: 9755:LOC102978444
uniprot id: A0A2Y9FJ47
names: Similarity
messages: Belongs to the calcitonin family.

9755:FAM8A1
gene id: 9755:FAM8A1
uniprot id: A0A2Y9SN98
uniprot id: A0A455AHT6
names: Subcellular Location Annotation
messages: Membrane

9755:ADSL
gene id: 9755:ADSL
uniprot id: A0A2Y9T2Q6
uniprot id: A0A455BBT8
uniprot id: A0A455BCG1
uniprot id: A0A455BCK3
uniprot id: A0A455BRE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

9755:LOC112064947
gene id: 9755:LOC112064947
uniprot id: A0A455AFU4
names: Subcellular Location Annotation
messages: Mitochondrion intermembrane space

9755:CD99L2
gene id: 9755:CD99L2
uniprot id: A0A2Y9S8H0
uniprot id: A0A455AP36
uniprot id: A0A455APC0
uniprot id: A0A455AQQ7
uniprot id: A0A455AR74
uniprot id: A0A455B312
names: Similarity
messages: Belongs to the CD99 family.

9755:GK2
gene id: 9755:GK2
uniprot id: A0A2Y9FHW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FGGY kinase family.
messages: Cytoplasm

9755:KCNG1
gene id: 9755:KCNG1
uniprot id: A0A2Y9SZT6
names: Subcellular Location Annotation
messages: Membrane

9755:PSMA1
gene id: 9755:PSMA1
uniprot id: A0A2Y9FF77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

9755:NKG7
gene id: 9755:NKG7
uniprot id: A0A2Y9F1D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

9755:LOC102989786
gene id: 9755:LOC102989786
uniprot id: A0A2Y9EHV3
names: Caution
names: Similarity
messages: Belongs to the seminal plasma protein family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:PIGF
gene id: 9755:PIGF
uniprot id: A0A2Y9ETJ6
uniprot id: A0A2Y9ETS1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:LYRM2
gene id: 9755:LYRM2
uniprot id: A0A2Y9FN17
names: Similarity
messages: Belongs to the complex I LYR family.

9755:PDCD5
gene id: 9755:PDCD5
uniprot id: A0A2Y9THW4
names: Similarity
messages: Belongs to the PDCD5 family.

9755:ERMP1
gene id: 9755:ERMP1
uniprot id: A0A2Y9ESL2
uniprot id: A0A455BLB3
uniprot id: A0A455BLJ6
uniprot id: A0A455C1A3
names: Subcellular Location Annotation
messages: Membrane

9755:PPA2
gene id: 9755:PPA2
uniprot id: A0A2Y9S8M2
uniprot id: A0A455BG55
uniprot id: A0A455BGT9
names: Similarity
messages: Belongs to the PPase family.

9755:PPP1R12B
gene id: 9755:PPP1R12B
uniprot id: A0A455B507
uniprot id: A0A455B514
uniprot id: A0A455B5E4
uniprot id: A0A455B5E8
uniprot id: A0A455B5F8
uniprot id: A0A455B5Y1
uniprot id: A0A455B5Y6
uniprot id: A0A455B7P0
uniprot id: A0A455B7P5
uniprot id: A0A455BJA3
uniprot id: A0A455BJA8
names: Subcellular Location Annotation
names: Subunit
messages: PP1 comprises a catalytic subunit, and one or several targeting or regulatory subunits.
messages: stress fiber

9755:ALAS2
gene id: 9755:ALAS2
uniprot id: A0A2Y9SAU4
uniprot id: A0A455AQ86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion inner membrane

9755:SLC35A3
gene id: 9755:SLC35A3
uniprot id: A0A2Y9F6A4
uniprot id: A0A2Y9SA55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9755:TM6SF2
gene id: 9755:TM6SF2
uniprot id: A0A2Y9F9U9
uniprot id: A0A455C4Y3
uniprot id: A0A455C4Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TM6SF family.
messages: Membrane

9755:DYNC1LI1
gene id: 9755:DYNC1LI1
uniprot id: A0A2Y9FL80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

9755:IL1R1
gene id: 9755:IL1R1
uniprot id: A0A2Y9FCY5
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

9755:GANC
gene id: 9755:GANC
uniprot id: A0A2Y9EM75
uniprot id: A0A455BQG9
uniprot id: A0A455BQH9
uniprot id: A0A455BQI1
uniprot id: A0A455BR57
uniprot id: A0A455BR63
uniprot id: A0A455BTT4
uniprot id: A0A455BTT8
uniprot id: A0A455BTU1
uniprot id: A0A455C5L4
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

9755:TMEM30B
gene id: 9755:TMEM30B
uniprot id: A0A2Y9S5N2
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

9755:NDC80
gene id: 9755:NDC80
uniprot id: A0A2Y9SM96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the NDC80/HEC1 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

9755:MRPL13
gene id: 9755:MRPL13
uniprot id: A0A2Y9FC97
uniprot id: A0A455C3K5
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

9755:PUSL1
gene id: 9755:PUSL1
uniprot id: A0A2Y9FRH1
uniprot id: A0A2Y9FTC6
uniprot id: A0A2Y9FU85
uniprot id: A0A455B4U1
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

9755:NEDD4L
gene id: 9755:NEDD4L
uniprot id: A0A455AHL7
uniprot id: A0A455AJA6
uniprot id: A0A455AVC8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:NAB1
gene id: 9755:NAB1
uniprot id: A0A2Y9S5E8
uniprot id: A0A455AHL1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAB family.
messages: Homomultimers may associate with EGR1 bound to DNA.
messages: Nucleus

9755:ZNF496
gene id: 9755:ZNF496
uniprot id: A0A2Y9FJX1
uniprot id: A0A2Y9TKP9
uniprot id: A0A455C3M7
names: Subcellular Location Annotation
messages: Nucleus

9755:MAP6D1
gene id: 9755:MAP6D1
uniprot id: A0A2Y9SWQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STOP family.
messages: cytoskeleton

9755:LGI1
gene id: 9755:LGI1
uniprot id: A0A2Y9FCB6
uniprot id: A0A2Y9FEF4
uniprot id: A0A2Y9SNL2
names: Subcellular Location Annotation
messages: Secreted

9755:COQ5
gene id: 9755:COQ5
uniprot id: A0A2Y9FV18
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
messages: Mitochondrion inner membrane

9755:PAX7
gene id: 9755:PAX7
uniprot id: A0A2Y9ELQ5
uniprot id: A0A2Y9EMI0
uniprot id: A0A2Y9EMQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

9755:C11H15orf40
gene id: 9755:C11H15orf40
uniprot id: A0A2Y9SBJ2
names: Similarity
messages: Belongs to the UPF0235 family.

9755:COQ10B
gene id: 9755:COQ10B
uniprot id: A0A2Y9EZS1
uniprot id: A0A2Y9SQ39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

9755:FAM120C
gene id: 9755:FAM120C
uniprot id: A0A2Y9SVL4
uniprot id: A0A2Y9SZD2
uniprot id: A0A455AN58
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

9755:COPA
gene id: 9755:COPA
uniprot id: A0A2Y9FSD0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.

9755:JAK2
gene id: 9755:JAK2
uniprot id: A0A2Y9SYZ0
uniprot id: A0A455BLA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system
messages: Nucleus

9755:NCAPH
gene id: 9755:NCAPH
uniprot id: A0A2Y9FAI6
uniprot id: A0A2Y9FAJ5
uniprot id: A0A2Y9FAW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND2 (condensin subunit 2) family.
messages: Chromosome
messages: Cytoplasm
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.

9755:PTGDS
gene id: 9755:PTGDS
uniprot id: A0A2Y9FNN0
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

9755:GADL1
gene id: 9755:GADL1
uniprot id: A0A2Y9FBD9
uniprot id: A0A455AGF2
uniprot id: A0A455AIM4
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

9755:ITGB5
gene id: 9755:ITGB5
uniprot id: A0A455BLH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

9755:SGCD
gene id: 9755:SGCD
uniprot id: A0A455BJQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

9755:ADAM7
gene id: 9755:ADAM7
uniprot id: A0A2Y9TEM7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:PTPRT
gene id: 9755:PTPRT
uniprot id: A0A2Y9SZS1
uniprot id: A0A2Y9T5W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Membrane

9755:RAB33B
gene id: 9755:RAB33B
uniprot id: A0A2Y9EKG9
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

9755:ZFHX2
gene id: 9755:ZFHX2
uniprot id: A0A2Y9S6G4
names: Subcellular Location Annotation
messages: Nucleus

9755:RAP2C
gene id: 9755:RAP2C
uniprot id: A0A2Y9FTX4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Palmitoylated.
messages: Recycling endosome membrane
messages: Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form.

9755:ATG4A
gene id: 9755:ATG4A
uniprot id: A0A455AP40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

9755:RRAGA
gene id: 9755:RRAGA
uniprot id: A0A2Y9FJ19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

9755:DNTT
gene id: 9755:DNTT
uniprot id: A0A2Y9F9N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Nucleus
messages: Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator.

9755:TRMT1L
gene id: 9755:TRMT1L
uniprot id: A0A2Y9TF65
uniprot id: A0A455B614
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: May play a role in motor coordination and exploratory behavior.

9755:RPL31
gene id: 9755:RPL31
uniprot id: A0A2Y9FF55
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Component of the large ribosomal subunit.

9755:ANKH
gene id: 9755:ANKH
uniprot id: A0A2Y9EI27
uniprot id: A0A2Y9EIQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKH family.
messages: Membrane
messages: Regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter.

9755:CLDN9
gene id: 9755:CLDN9
uniprot id: A0A2Y9EDC9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9755:GDI1
gene id: 9755:GDI1
uniprot id: A0A455APD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

9755:TMEM242
gene id: 9755:TMEM242
uniprot id: A0A2Y9SIG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM242 family.
messages: Membrane

9755:MAML2
gene id: 9755:MAML2
uniprot id: A0A2Y9ENS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

9755:FMC1
gene id: 9755:FMC1
uniprot id: A0A2Y9EPE2
names: Similarity
messages: Belongs to the FMC1 family.

9755:ARPC3
gene id: 9755:ARPC3
uniprot id: A0A2Y9ELT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC3 family.
messages: Component of the Arp2/3 complex.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

9755:TLR5
gene id: 9755:TLR5
uniprot id: A0A2Y9FFB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

9755:MGAT5B
gene id: 9755:MGAT5B
uniprot id: A0A2Y9TDM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 18 family.
messages: Golgi apparatus membrane
messages: Membrane

9755:CLK1
gene id: 9755:CLK1
uniprot id: A0A2Y9ESI5
names: Similarity
messages: Belongs to the protein kinase superfamily.

9755:ACOX3
gene id: 9755:ACOX3
uniprot id: A0A2Y9EV37
uniprot id: A0A455BGT3
uniprot id: A0A455BH84
uniprot id: A0A455BJV4
uniprot id: A0A455BWH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

9755:LOC102992218
gene id: 9755:LOC102992218
uniprot id: A0A2Y9F3S7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9755:AGPAT5
gene id: 9755:AGPAT5
uniprot id: A0A455AMN4
uniprot id: A0A455AMV2
uniprot id: A0A455APP5
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

9755:LOC102976721
gene id: 9755:LOC102976721
uniprot id: A0A2Y9SXK7
names: Subcellular Location Annotation
messages: spindle

9755:C20H4orf47
gene id: 9755:C20H4orf47
uniprot id: A0A2Y9F8A2
uniprot id: A0A455AKW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP96 family.
messages: centrosome

9755:DYNLT4
gene id: 9755:DYNLT4
uniprot id: A0A2Y9EY51
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

9755:LOC102975914
gene id: 9755:LOC102975914
uniprot id: A0A2Y9ELJ9
names: Similarity
messages: Belongs to the PRAME family.

9755:FOXK2
gene id: 9755:FOXK2
uniprot id: A0A2Y9T664
uniprot id: A0A455C207
names: Subcellular Location Annotation
messages: Nucleus

9755:ZRANB1
gene id: 9755:ZRANB1
uniprot id: A0A2Y9SEX0
names: Similarity
messages: Belongs to the peptidase C64 family.

9755:HPS3
gene id: 9755:HPS3
uniprot id: A0A2Y9TFI9
uniprot id: A0A2Y9TH78
uniprot id: A0A455B9E5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the biogenesis of lysosome-related organelles complex-2 (or BLOC2) composed of HPS3, HPS5 and HPS6.
messages: Cytoplasm
messages: Involved in early stages of melanosome biogenesis and maturation.

9755:MTAP
gene id: 9755:MTAP
uniprot id: A0A2Y9FEB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Cytoplasm
messages: Homotrimer.
messages: Nucleus

9755:KDM4A
gene id: 9755:KDM4A
uniprot id: A0A2Y9F763
uniprot id: A0A2Y9SZ78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM3 histone demethylase family.
messages: Nucleus

9755:AKAP5
gene id: 9755:AKAP5
uniprot id: A0A2Y9EIC6
names: Subcellular Location Annotation
messages: Membrane

9755:HMMR
gene id: 9755:HMMR
uniprot id: A0A2Y9FF60
uniprot id: A0A2Y9FH11
uniprot id: A0A2Y9RYQ5
uniprot id: A0A2Y9S2C9
uniprot id: A0A2Y9S606
names: Subcellular Location Annotation
messages: spindle

9755:TMC8
gene id: 9755:TMC8
uniprot id: A0A2Y9T8J2
uniprot id: A0A455BZX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

9755:CCNJL
gene id: 9755:CCNJL
uniprot id: A0A2Y9EMW0
names: Similarity
messages: Belongs to the cyclin family.

9755:KDR
gene id: 9755:KDR
uniprot id: A0A2Y9FEK6
uniprot id: A0A455BF76
uniprot id: A0A455BFW0
uniprot id: A0A455BIA2
uniprot id: A0A455BUW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

9755:LOC102990876
gene id: 9755:LOC102990876
uniprot id: A0A2Y9EKF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

9755:TPP2
gene id: 9755:TPP2
uniprot id: A0A2Y9SKJ5
uniprot id: A0A2Y9ST32
uniprot id: A0A455BYE5
uniprot id: A0A455C190
uniprot id: A0A455C9Y6
names: Caution
names: Similarity
messages: Belongs to the peptidase S8 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:MYLK
gene id: 9755:MYLK
uniprot id: A0A455BY94
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

9755:ANO9
gene id: 9755:ANO9
uniprot id: A0A455AGH4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:PFKP
gene id: 9755:PFKP
uniprot id: A0A2Y9EZ51
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:IFNAR2
gene id: 9755:IFNAR2
uniprot id: A0A2Y9SCL7
uniprot id: A0A2Y9SFS8
uniprot id: A0A2Y9SIL4
names: Subcellular Location Annotation
messages: Membrane

9755:UBL3
gene id: 9755:UBL3
uniprot id: A0A2Y9EHV6
uniprot id: A0A455BXJ7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9755:IL5
gene id: 9755:IL5
uniprot id: A0A2Y9EY78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-5 family.
messages: Homodimer; disulfide-linked. Interacts with IL5RA. Interacts with CSF2RB.
messages: Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Acts also on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation (By similarity). Mechanistically, exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB. Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively.
messages: Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Acts also on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation. Mechanistically, exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB. Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively.
messages: Secreted

9755:RRS1
gene id: 9755:RRS1
uniprot id: A0A2Y9FCU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRS1 family.
messages: Involved in ribosomal large subunit assembly.
messages: Nucleus

9755:HOXB4
gene id: 9755:HOXB4
uniprot id: A0A2Y9EVF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

9755:FXYD2
gene id: 9755:FXYD2
uniprot id: A0A2Y9EHW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FXYD family.
messages: May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase.
messages: Membrane
messages: Regulatory subunit of the sodium/potassium-transporting ATPase which is composed of a catalytic alpha subunit, an auxiliary non-catalytic beta subunit and an additional regulatory subunit.

9755:USP15
gene id: 9755:USP15
uniprot id: A0A2Y9EM98
uniprot id: A0A2Y9EME2
uniprot id: A0A2Y9ENN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: Nucleus

9755:SPSB4
gene id: 9755:SPSB4
uniprot id: A0A2Y9ERZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

9755:EEF1D
gene id: 9755:EEF1D
uniprot id: A0A2Y9F328
uniprot id: A0A2Y9S447
uniprot id: A0A2Y9SBY4
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.

9755:LOC102978095
gene id: 9755:LOC102978095
uniprot id: A0A2Y9FQJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

9755:ALG5
gene id: 9755:ALG5
uniprot id: A0A2Y9FTS3
uniprot id: A0A2Y9SWG8
uniprot id: A0A2Y9SYT6
uniprot id: A0A455C9C3
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

9755:GMFG
gene id: 9755:GMFG
uniprot id: A0A2Y9F4P4
names: Similarity
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.

9755:MRPL22
gene id: 9755:MRPL22
uniprot id: A0A2Y9EZ79
uniprot id: A0A2Y9F130
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

9755:ACVR1C
gene id: 9755:ACVR1C
uniprot id: A0A2Y9EKQ5
uniprot id: A0A2Y9ELJ4
uniprot id: A0A2Y9SH87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

9755:SLFN11
gene id: 9755:SLFN11
uniprot id: A0A2Y9ENE6
names: Similarity
messages: Belongs to the Schlafen family. Subgroup III subfamily.

9755:LOC112062286
gene id: 9755:LOC112062286
uniprot id: A0A2Y9S8F5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

9755:PRDM10
gene id: 9755:PRDM10
uniprot id: A0A2Y9FFT5
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

9755:PARP2
gene id: 9755:PARP2
uniprot id: A0A2Y9FNW6
uniprot id: A0A2Y9FQT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Nucleus

9755:LOC102988948
gene id: 9755:LOC102988948
uniprot id: A0A2Y9FGB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

9755:PDHX
gene id: 9755:PDHX
uniprot id: A0A2Y9FS54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Mitochondrion matrix

9755:SMUG1
gene id: 9755:SMUG1
uniprot id: A0A2Y9SJP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. SMUG1 family.
messages: Nucleus

9755:HCAR1
gene id: 9755:HCAR1
uniprot id: A0A2Y9FUU3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9755:CCL26
gene id: 9755:CCL26
uniprot id: A0A2Y9T002
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.

9755:ESX1
gene id: 9755:ESX1
uniprot id: A0A2Y9FB99
names: Subcellular Location Annotation
messages: Nucleus

9755:MED12L
gene id: 9755:MED12L
uniprot id: A0A2Y9T9I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 12 family.
messages: Nucleus

9755:LOC102994747
gene id: 9755:LOC102994747
uniprot id: A0A2Y9FAP9
names: Similarity
messages: Belongs to the GroES chaperonin family.

9755:IREB2
gene id: 9755:IREB2
uniprot id: A0A2Y9T0T3
uniprot id: A0A455BQF0
uniprot id: A0A455BT05
uniprot id: A0A455C4T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Cytoplasm

9755:MARS2
gene id: 9755:MARS2
uniprot id: A0A455AIV2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9755:LOC102983776
gene id: 9755:LOC102983776
uniprot id: A0A2Y9RXY4
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9755:LOC102987585
gene id: 9755:LOC102987585
uniprot id: A0A2Y9T0F9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Component of the signal peptidase complex.
messages: Endoplasmic reticulum membrane

9755:NOP14
gene id: 9755:NOP14
uniprot id: A0A455BWL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP14 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
messages: nucleolus

9755:KATNAL2
gene id: 9755:KATNAL2
uniprot id: A0A2Y9TER2
uniprot id: A0A455AH78
uniprot id: A0A455AH87
uniprot id: A0A455AHP6
uniprot id: A0A455AHQ0
uniprot id: A0A455AJ45
uniprot id: A0A455AJD7
uniprot id: A0A455AJE1
uniprot id: A0A455AVG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 2 sub-subfamily.
messages: Cytoplasm
messages: Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.
messages: cytoskeleton
messages: spindle
messages: spindle pole

9755:CDH15
gene id: 9755:CDH15
uniprot id: A0A455ACK2
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

9755:KCNS2
gene id: 9755:KCNS2
uniprot id: A0A2Y9F7Z8
names: Subcellular Location Annotation
messages: Membrane

9755:XPA
gene id: 9755:XPA
uniprot id: A0A2Y9T1B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPA family.
messages: Nucleus

9755:PHOSPHO2
gene id: 9755:PHOSPHO2
uniprot id: A0A2Y9EVJ0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.

9755:FIBIN
gene id: 9755:FIBIN
uniprot id: A0A2Y9FA61
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FIBIN family.
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer; disulfide-linked. Seems to also exist as monomers.
messages: Secreted

9755:CTNS
gene id: 9755:CTNS
uniprot id: A0A2Y9FLN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cystinosin family.
messages: Membrane

9755:REM1
gene id: 9755:REM1
uniprot id: A0A2Y9FIU6
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

9755:ARL5A
gene id: 9755:ARL5A
uniprot id: A0A2Y9ESZ8
uniprot id: A0A2Y9EUP5
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

9755:FTCD
gene id: 9755:FTCD
uniprot id: A0A2Y9SBV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds and promotes bundling of vimentin filaments originating from the Golgi.
messages: Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool.
messages: Golgi apparatus
messages: Homooctamer, including four polyglutamate binding sites. The subunits are arranged as a tetramer of dimers, and form a planar ring-shaped structure.
messages: In the C-terminal section; belongs to the cyclodeaminase/cyclohydrolase family.
messages: In the N-terminal section; belongs to the formiminotransferase family.
messages: centriole

9755:LOC102990938
gene id: 9755:LOC102990938
uniprot id: A0A2Y9FAT8
names: Similarity
messages: Belongs to the CD225/Dispanin family.

9755:SRPRA
gene id: 9755:SRPRA
uniprot id: A0A2Y9FJA0
uniprot id: A0A2Y9FJG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:TAS2R42
gene id: 9755:TAS2R42
uniprot id: A0A2Y9T8H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

9755:INO80D
gene id: 9755:INO80D
uniprot id: A0A2Y9EYE1
names: Subcellular Location Annotation
messages: Nucleus

9755:VPS13A
gene id: 9755:VPS13A
uniprot id: A0A2Y9SYV2
uniprot id: A0A2Y9T0Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS13 family.
messages: Lipid droplet

9755:RNASET2
gene id: 9755:RNASET2
uniprot id: A0A2Y9SLZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase T2 family.
messages: Lysosome lumen

9755:CEBPD
gene id: 9755:CEBPD
uniprot id: A0A2Y9SZS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. C/EBP subfamily.
messages: Nucleus

9755:NNT
gene id: 9755:NNT
uniprot id: A0A2Y9S9V7
names: Similarity
messages: In the N-terminal section; belongs to the AlaDH/PNT family.

9755:REEP5
gene id: 9755:REEP5
uniprot id: A0A2Y9T155
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

9755:SLC6A3
gene id: 9755:SLC6A3
uniprot id: A0A2Y9EPK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A3 subfamily.
messages: Cell membrane
messages: Membrane
messages: axon
messages: neuron projection

9755:LOC102981758
gene id: 9755:LOC102981758
uniprot id: A0A2Y9S3W1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.

9755:LOC102980272
gene id: 9755:LOC102980272
uniprot id: A0A455AT66
names: Similarity
messages: Belongs to the peptidase S9C family.

9755:UGP2
gene id: 9755:UGP2
uniprot id: A0A2Y9EZD9
uniprot id: A0A2Y9F0C6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDPGP type 1 family.
messages: Homooctamer.
messages: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.

9755:EDA
gene id: 9755:EDA
uniprot id: A0A2Y9S111
uniprot id: A0A2Y9S124
uniprot id: A0A2Y9S4K5
uniprot id: A0A2Y9S7V8
uniprot id: A0A2Y9S7W1
uniprot id: A0A2Y9S924
names: Similarity
messages: Belongs to the tumor necrosis factor family.

9755:LOC129391332
gene id: 9755:LOC129391332
uniprot id: A0A455C0T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

9755:CNTFR
gene id: 9755:CNTFR
uniprot id: A0A2Y9TCM9
names: Similarity
messages: Belongs to the type I cytokine receptor family. Type 3 subfamily.

9755:PKN3
gene id: 9755:PKN3
uniprot id: A0A2Y9EJT2
uniprot id: A0A2Y9SV14
uniprot id: A0A455C0K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Nucleus

9755:LOC102979261
gene id: 9755:LOC102979261
uniprot id: A0A2Y9FET2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:NELFE
gene id: 9755:NELFE
uniprot id: A0A2Y9EWK6
uniprot id: A0A2Y9EXY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM NELF-E family.
messages: Chromosome
messages: Nucleus

9755:CMTM8
gene id: 9755:CMTM8
uniprot id: A0A2Y9S117
names: Subcellular Location Annotation
messages: Membrane

9755:DDX59
gene id: 9755:DDX59
uniprot id: A0A2Y9FNY4
uniprot id: A0A2Y9T826
uniprot id: A0A455B5J5
uniprot id: A0A455B7V2
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX59 subfamily.

9755:SNX7
gene id: 9755:SNX7
uniprot id: A0A2Y9F8T0
uniprot id: A0A2Y9F936
uniprot id: A0A2Y9F9G3
names: Similarity
messages: Belongs to the sorting nexin family.

9755:NLK
gene id: 9755:NLK
uniprot id: A0A2Y9FFM2
uniprot id: A0A455C374
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

9755:GUCA2B
gene id: 9755:GUCA2B
uniprot id: A0A2Y9EJX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylin family.
messages: Secreted

9755:ING2
gene id: 9755:ING2
uniprot id: A0A2Y9EFY7
uniprot id: A0A455B060
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

9755:CLTB
gene id: 9755:CLTB
uniprot id: A0A2Y9S0H3
uniprot id: A0A455C9T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

9755:PLSCR5
gene id: 9755:PLSCR5
uniprot id: A0A2Y9FAX6
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

9755:TMOD2
gene id: 9755:TMOD2
uniprot id: A0A2Y9T4Y6
names: Subcellular Location Annotation
messages: cytoskeleton

9755:IL17RA
gene id: 9755:IL17RA
uniprot id: A0A455BCW9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9755:EDN1
gene id: 9755:EDN1
uniprot id: A0A2Y9EKQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

9755:PITX1
gene id: 9755:PITX1
uniprot id: A0A2Y9SR39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

9755:LHCGR
gene id: 9755:LHCGR
uniprot id: A0A2Y9S829
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

9755:THYN1
gene id: 9755:THYN1
uniprot id: A0A2Y9EK97
uniprot id: A0A2Y9ELN6
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

9755:ISCA2
gene id: 9755:ISCA2
uniprot id: A0A2Y9F8E0
uniprot id: A0A2Y9FA41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HesB/IscA family.
messages: Mitochondrion

9755:LOC102992127
gene id: 9755:LOC102992127
uniprot id: A0A2Y9FTB5
names: Similarity
messages: Belongs to the intermediate filament family.

9755:TRPV1
gene id: 9755:TRPV1
uniprot id: A0A2Y9FLM8
names: Subcellular Location Annotation
messages: Membrane

9755:CHSY1
gene id: 9755:CHSY1
uniprot id: A0A2Y9RVV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

9755:RP2
gene id: 9755:RP2
uniprot id: A0A2Y9FHF1
uniprot id: A0A2Y9FJ80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.
messages: Belongs to the TBCC family.
messages: Cell membrane
messages: Membrane

9755:AGPAT3
gene id: 9755:AGPAT3
uniprot id: A0A2Y9SJY6
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

9755:LOC112066114
gene id: 9755:LOC112066114
uniprot id: A0A455ANH2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9755:XIRP2
gene id: 9755:XIRP2
uniprot id: A0A2Y9FB15
uniprot id: A0A455AE19
names: Domain
names: Function
names: Similarity
messages: Belongs to the Xin family.
messages: Protects actin filaments from depolymerization.
messages: Xin repeats bind F-actin.

9755:ATP13A2
gene id: 9755:ATP13A2
uniprot id: A0A2Y9F3Y4
uniprot id: A0A2Y9F413
uniprot id: A0A2Y9F5P2
uniprot id: A0A2Y9SS45
uniprot id: A0A455B3T0
uniprot id: A0A455BI15
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:EOGT
gene id: 9755:EOGT
uniprot id: A0A2Y9SQM4
names: Similarity
messages: Belongs to the glycosyltransferase 61 family.

9755:GTF2H4
gene id: 9755:GTF2H4
uniprot id: A0A2Y9EPR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.
messages: Nucleus

9755:TCP11L1
gene id: 9755:TCP11L1
uniprot id: A0A2Y9EXY0
names: Similarity
messages: Belongs to the TCP11 family.

9755:GTF2E1
gene id: 9755:GTF2E1
uniprot id: A0A2Y9SKD8
names: Function
names: Similarity
messages: Belongs to the TFIIE alpha subunit family.
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.

9755:CTNNB1
gene id: 9755:CTNNB1
uniprot id: A0A2Y9F1X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: adherens junction

9755:BBS5
gene id: 9755:BBS5
uniprot id: A0A2Y9FGJ2
uniprot id: A0A2Y9FGN8
uniprot id: A0A455ARX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BBS5 family.
messages: Membrane
messages: Part of BBSome complex, that contains BBS1, BBS2, BBS4, BBS5, BBS7, BBS8/TTC8, BBS9 and BBIP10.
messages: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for BBSome complex ciliary localization but not for the proper complex assembly.
messages: centriolar satellite
messages: cilium membrane

9755:LOC102976301
gene id: 9755:LOC102976301
uniprot id: A0A2Y9FMR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Secreted

9755:SSH3
gene id: 9755:SSH3
uniprot id: A0A2Y9EWZ8
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

9755:INTS3
gene id: 9755:INTS3
uniprot id: A0A2Y9FVJ9
names: Similarity
messages: Belongs to the Integrator subunit 3 family.

9755:CCNJ
gene id: 9755:CCNJ
uniprot id: A0A2Y9SG55
uniprot id: A0A2Y9SNS2
uniprot id: A0A455AKC4
names: Similarity
messages: Belongs to the cyclin family.

9755:LOC112066694
gene id: 9755:LOC112066694
uniprot id: A0A2Y9TC47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

9755:CEBPG
gene id: 9755:CEBPG
uniprot id: A0A2Y9FLZ6
uniprot id: A0A2Y9FME4
names: Similarity
messages: Belongs to the bZIP family. C/EBP subfamily.

9755:LOC102986459
gene id: 9755:LOC102986459
uniprot id: A0A2Y9EVS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9755:NXPE3
gene id: 9755:NXPE3
uniprot id: A0A2Y9EN50
uniprot id: A0A2Y9ENX4
names: Similarity
messages: Belongs to the NXPE family.

9755:CDH2
gene id: 9755:CDH2
uniprot id: A0A2Y9SGT6
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

9755:DNAI7
gene id: 9755:DNAI7
uniprot id: A0A2Y9EF22
names: Similarity
messages: Belongs to the DNAI7 family.

9755:CFAP68
gene id: 9755:CFAP68
uniprot id: A0A2Y9FQ72
names: Function
names: Subcellular Location Annotation
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.
messages: cilium axoneme

9755:RPF1
gene id: 9755:RPF1
uniprot id: A0A2Y9ENR9
names: Subcellular Location Annotation
messages: nucleolus

9755:WEE1
gene id: 9755:WEE1
uniprot id: A0A2Y9F794
uniprot id: A0A2Y9F8V1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
messages: Binds 2 magnesium ions per subunit.
messages: Nucleus

9755:CFAP418
gene id: 9755:CFAP418
uniprot id: A0A2Y9EZ27
uniprot id: A0A2Y9EZM2
uniprot id: A0A455C511
uniprot id: A0A455C8R0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in photoreceptor outer segment disk morphogenesis.
messages: Photoreceptor inner segment

9755:SPIN1
gene id: 9755:SPIN1
uniprot id: A0A2Y9T8E0
names: Similarity
messages: Belongs to the SPIN/STSY family.

9755:NXPH2
gene id: 9755:NXPH2
uniprot id: A0A2Y9SP58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

9755:AP4B1
gene id: 9755:AP4B1
uniprot id: A0A2Y9EUC6
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

9755:NOL12
gene id: 9755:NOL12
uniprot id: A0A2Y9F014
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRP17 family.
messages: Interacts with KIAA1191.
messages: nucleolus

9755:CAPN1
gene id: 9755:CAPN1
uniprot id: A0A2Y9F8M2
uniprot id: A0A2Y9F9B6
uniprot id: A0A455C9A0
names: Similarity
messages: Belongs to the peptidase C2 family.

9755:RBBP5
gene id: 9755:RBBP5
uniprot id: A0A2Y9FUI6
uniprot id: A0A2Y9FUN9
uniprot id: A0A2Y9FWM3
names: Subcellular Location Annotation
messages: Nucleus

9755:TSC22D2
gene id: 9755:TSC22D2
uniprot id: A0A2Y9EE01
uniprot id: A0A2Y9EF76
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

9755:NPR2
gene id: 9755:NPR2
uniprot id: A0A2Y9ETY7
uniprot id: A0A2Y9EVB6
uniprot id: A0A2Y9T1V1
uniprot id: A0A455BLK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

9755:NRG3
gene id: 9755:NRG3
uniprot id: A0A2Y9TE79
uniprot id: A0A455B022
names: Caution
names: Similarity
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:ARID3C
gene id: 9755:ARID3C
uniprot id: A0A455BLW1
uniprot id: A0A455BMC4
uniprot id: A0A455BPW3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer.
messages: Nucleus
messages: Transcription factor.

9755:EBF4
gene id: 9755:EBF4
uniprot id: A0A2Y9S6F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

9755:VEGFD
gene id: 9755:VEGFD
uniprot id: A0A455BX13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Secreted

9755:MTERF4
gene id: 9755:MTERF4
uniprot id: A0A2Y9FPG0
names: Similarity
messages: Belongs to the mTERF family.

9755:CPNE8
gene id: 9755:CPNE8
uniprot id: A0A2Y9SJC8
uniprot id: A0A2Y9SM61
names: Similarity
messages: Belongs to the copine family.

9755:TM4SF5
gene id: 9755:TM4SF5
uniprot id: A0A2Y9EUA2
uniprot id: A0A2Y9SXG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

9755:YDJC
gene id: 9755:YDJC
uniprot id: A0A2Y9FX94
uniprot id: A0A455AHK2
uniprot id: A0A455AI26
uniprot id: A0A455AJI9
uniprot id: A0A455AJP5
names: Function
names: Similarity
messages: Belongs to the YdjC deacetylase family.
messages: Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides.

9755:SF3A3
gene id: 9755:SF3A3
uniprot id: A0A455B5H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3A3 family.
messages: Nucleus

9755:NAPRT
gene id: 9755:NAPRT
uniprot id: A0A2Y9F140
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

9755:GIMAP4
gene id: 9755:GIMAP4
uniprot id: A0A2Y9FHU8
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

9755:LOC102980294
gene id: 9755:LOC102980294
uniprot id: A0A2Y9FA37
uniprot id: A0A455APU7
uniprot id: A0A455ARQ5
names: Similarity
messages: Belongs to the SNF7 family.

9755:PNOC
gene id: 9755:PNOC
uniprot id: A0A2Y9TCZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Secreted

9755:SERPINA7
gene id: 9755:SERPINA7
uniprot id: A0A2Y9EI49
names: Similarity
messages: Belongs to the serpin family.

9755:NARF
gene id: 9755:NARF
uniprot id: A0A2Y9FKY0
uniprot id: A0A455CAL3
names: Similarity
messages: Belongs to the NARF family.

9755:HM13
gene id: 9755:HM13
uniprot id: A0A455C1Q7
uniprot id: A0A455C4X8
uniprot id: A0A455CAM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

9755:SLC31A2
gene id: 9755:SLC31A2
uniprot id: A0A2Y9EV19
uniprot id: A0A2Y9SUH2
uniprot id: A0A2Y9T2K0
uniprot id: A0A455BKN0
uniprot id: A0A455BKN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

9755:TULP3
gene id: 9755:TULP3
uniprot id: A0A2Y9FA04
uniprot id: A0A455BDA2
uniprot id: A0A455BFM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUB family.
messages: Secreted

9755:ADGRG6
gene id: 9755:ADGRG6
uniprot id: A0A2Y9SIE9
uniprot id: A0A455BMG1
uniprot id: A0A455BN64
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:SDHB
gene id: 9755:SDHB
uniprot id: A0A455B4T9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Iron-sulfur protein (IP) subunit of the succinate dehydrogenase complex (mitochondrial respiratory chain complex II), responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

9755:CDT1
gene id: 9755:CDT1
uniprot id: A0A2Y9SW19
names: Similarity
messages: Belongs to the Cdt1 family.

9755:CPT1A
gene id: 9755:CPT1A
uniprot id: A0A455C9M7
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

9755:ASPDH
gene id: 9755:ASPDH
uniprot id: A0A2Y9EK06
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.

9755:TSPOAP1
gene id: 9755:TSPOAP1
uniprot id: A0A2Y9SZR4
uniprot id: A0A2Y9T4B1
names: Similarity
messages: Belongs to the RIMBP family.

9755:LOC102990513
gene id: 9755:LOC102990513
uniprot id: A0A2Y9FJG1
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.

9755:GLRB
gene id: 9755:GLRB
uniprot id: A0A2Y9SUU1
uniprot id: A0A2Y9T0S0
uniprot id: A0A455BF35
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9755:APPL2
gene id: 9755:APPL2
uniprot id: A0A2Y9F3G2
uniprot id: A0A2Y9F564
uniprot id: A0A455BEI2
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: Nucleus
messages: phagosome
messages: ruffle

9755:SMIM15
gene id: 9755:SMIM15
uniprot id: A0A2Y9FBP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM15 family.
messages: Membrane

9755:OPRD1
gene id: 9755:OPRD1
uniprot id: A0A2Y9SUZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9755:TMPRSS11A
gene id: 9755:TMPRSS11A
uniprot id: A0A2Y9FG81
uniprot id: A0A2Y9FGH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Membrane

9755:KIF11
gene id: 9755:KIF11
uniprot id: A0A2Y9SIE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-5/BimC subfamily.
messages: spindle pole

9755:CHMP2B
gene id: 9755:CHMP2B
uniprot id: A0A2Y9EJT4
names: Similarity
messages: Belongs to the SNF7 family.

9755:TMEM265
gene id: 9755:TMEM265
uniprot id: A0A2Y9SP88
names: Similarity
messages: Belongs to the CD225/Dispanin family.

9755:AKAP12
gene id: 9755:AKAP12
uniprot id: A0A2Y9SIN6
uniprot id: A0A2Y9SRC8
names: Subcellular Location Annotation
messages: Membrane

9755:PNLIP
gene id: 9755:PNLIP
uniprot id: A0A2Y9FMW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

9755:LOC102991848
gene id: 9755:LOC102991848
uniprot id: A0A2Y9SLG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PET117 family.
messages: Mitochondrion

9755:LYZL6
gene id: 9755:LYZL6
uniprot id: A0A2Y9FKB7
uniprot id: A0A2Y9FKM8
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

9755:VPS16
gene id: 9755:VPS16
uniprot id: A0A2Y9SAV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS16 family.
messages: Early endosome
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes.
messages: Vesicle

9755:CASP10
gene id: 9755:CASP10
uniprot id: A0A2Y9F1D1
uniprot id: A0A2Y9SPK8
names: Similarity
messages: Belongs to the peptidase C14A family.

9755:NOP10
gene id: 9755:NOP10
uniprot id: A0A2Y9FQS2
names: Similarity
messages: Belongs to the NOP10 family.

9755:LOC102989742
gene id: 9755:LOC102989742
uniprot id: A0A2Y9SGK0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:SBNO1
gene id: 9755:SBNO1
uniprot id: A0A2Y9SCT3
uniprot id: A0A2Y9SJI8
names: Similarity
messages: Belongs to the SBNO family.

9755:SSR1
gene id: 9755:SSR1
uniprot id: A0A2Y9EEW6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-alpha family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma. Interacts with palmitoylated calnexin (CALX), the interaction is required for efficient folding of glycosylated proteins.
messages: Membrane
messages: Shows a remarkable charge distribution with the N-terminus being highly negatively charged, and the cytoplasmic C-terminus positively charged.
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins.

9755:LOC112062579
gene id: 9755:LOC112062579
uniprot id: A0A2Y9S3C3
names: Similarity
messages: Belongs to the histone H2B family.

9755:B3GAT2
gene id: 9755:B3GAT2
uniprot id: A0A2Y9TEG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

9755:WDR82
gene id: 9755:WDR82
uniprot id: A0A2Y9STB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SWD2 family.
messages: Nucleus

9755:LOC102988681
gene id: 9755:LOC102988681
uniprot id: A0A2Y9SJZ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9755:TRIP12
gene id: 9755:TRIP12
uniprot id: A0A2Y9FMY9
uniprot id: A0A2Y9FMZ4
uniprot id: A0A2Y9FPJ6
uniprot id: A0A2Y9FQC0
uniprot id: A0A2Y9SNU0
uniprot id: A0A2Y9SNU5
uniprot id: A0A2Y9SPU4
uniprot id: A0A2Y9SPU9
uniprot id: A0A2Y9SS94
uniprot id: A0A2Y9SUX9
uniprot id: A0A2Y9SUY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPL family. K-HECT subfamily.
messages: E3 ubiquitin-protein ligase involved in ubiquitin fusion degradation (UFD) pathway and regulation of DNA repair. Part of the ubiquitin fusion degradation (UFD) pathway, a process that mediates ubiquitination of protein at their N-terminus, regardless of the presence of lysine residues in target proteins.
messages: nucleoplasm

9755:NELL1
gene id: 9755:NELL1
uniprot id: A0A2Y9SBB3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:MYO6
gene id: 9755:MYO6
uniprot id: A0A455BNK6
uniprot id: A0A455BRQ6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: clathrin-coated pit
messages: clathrin-coated vesicle
messages: filopodium
messages: microvillus
messages: ruffle membrane
messages: trans-Golgi network membrane

9755:CLDN20
gene id: 9755:CLDN20
uniprot id: A0A455BS00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9755:GOSR1
gene id: 9755:GOSR1
uniprot id: A0A2Y9FI19
uniprot id: A0A2Y9FIJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GOSR1 family.
messages: Component of several multiprotein Golgi SNARE complexes.
messages: Golgi apparatus membrane
messages: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.
messages: Membrane

9755:EMP3
gene id: 9755:EMP3
uniprot id: A0A2Y9F010
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probably involved in cell proliferation and cell-cell interactions.

9755:SLC45A2
gene id: 9755:SLC45A2
uniprot id: A0A2Y9SJ18
names: Subcellular Location Annotation
messages: Membrane

9755:HADHA
gene id: 9755:HADHA
uniprot id: A0A2Y9EUD7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

9755:EPHA8
gene id: 9755:EPHA8
uniprot id: A0A455B982
names: Subcellular Location Annotation
messages: Membrane

9755:LOC112062563
gene id: 9755:LOC112062563
uniprot id: A0A2Y9SB75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

9755:EYA3
gene id: 9755:EYA3
uniprot id: A0A2Y9FDJ7
uniprot id: A0A2Y9FDS6
uniprot id: A0A2Y9SUE9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

9755:KCNK13
gene id: 9755:KCNK13
uniprot id: A0A2Y9T8S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

9755:LOC102996508
gene id: 9755:LOC102996508
uniprot id: A0A455AQ46
names: Function
names: Similarity
messages: Belongs to the OPA3 family.
messages: May play some role in mitochondrial processes.

9755:ARF4
gene id: 9755:ARF4
uniprot id: A0A2Y9FDI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

9755:SNX14
gene id: 9755:SNX14
uniprot id: A0A2Y9EYD2
uniprot id: A0A2Y9EYW0
uniprot id: A0A2Y9EZF5
uniprot id: A0A2Y9S5L5
uniprot id: A0A455BNB7
uniprot id: A0A455BNH5
uniprot id: A0A455BRM9
uniprot id: A0A455C3G8
names: Similarity
messages: Belongs to the sorting nexin family.

9755:GRIA2
gene id: 9755:GRIA2
uniprot id: A0A2Y9EXK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

9755:ABCB4
gene id: 9755:ABCB4
uniprot id: A0A455BPY8
names: Subcellular Location Annotation
messages: Membrane

9755:GPR17
gene id: 9755:GPR17
uniprot id: A0A2Y9FMU7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9755:NFRKB
gene id: 9755:NFRKB
uniprot id: A0A2Y9FFZ7
uniprot id: A0A455C666
names: Subcellular Location Annotation
messages: Nucleus

9755:PUS7L
gene id: 9755:PUS7L
uniprot id: A0A2Y9EQ07
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

9755:TRPC1
gene id: 9755:TRPC1
uniprot id: A0A2Y9FM41
uniprot id: A0A2Y9FMI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC1 sub-subfamily.
messages: Membrane
messages: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.

9755:GHRL
gene id: 9755:GHRL
uniprot id: A0A455AGJ6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the motilin family.
messages: Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation.
messages: O-octanoylation is essential for ghrelin activity.
messages: Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility.
messages: Secreted

9755:SVOP
gene id: 9755:SVOP
uniprot id: A0A455AIX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

9755:ADAMTS17
gene id: 9755:ADAMTS17
uniprot id: A0A2Y9RZP6
uniprot id: A0A455BT49
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9755:GABRA4
gene id: 9755:GABRA4
uniprot id: A0A2Y9FA62
uniprot id: A0A2Y9FAG8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9755:HABP2
gene id: 9755:HABP2
uniprot id: A0A2Y9EQG2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9755:HYOU1
gene id: 9755:HYOU1
uniprot id: A0A2Y9FIR8
uniprot id: A0A2Y9FIW8
names: Similarity
messages: Belongs to the heat shock protein 70 family.

9755:NUSAP1
gene id: 9755:NUSAP1
uniprot id: A0A2Y9EYX6
uniprot id: A0A2Y9F0T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NUSAP family.
messages: Cytoplasm

9755:SIRT2
gene id: 9755:SIRT2
uniprot id: A0A2Y9F427
uniprot id: A0A455ABI2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase.

9755:HBP1
gene id: 9755:HBP1
uniprot id: A0A2Y9ENS1
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

9755:TNS4
gene id: 9755:TNS4
uniprot id: A0A2Y9F060
uniprot id: A0A2Y9F0A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTEN phosphatase protein family.
messages: focal adhesion

9755:VGLL3
gene id: 9755:VGLL3
uniprot id: A0A2Y9F417
uniprot id: A0A2Y9F5P6
uniprot id: A0A2Y9SEY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.
messages: Nucleus

9755:MGAM
gene id: 9755:MGAM
uniprot id: A0A2Y9EIC7
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:B9D1
gene id: 9755:B9D1
uniprot id: A0A455C369
names: Subcellular Location Annotation
messages: cilium basal body

9755:HTT
gene id: 9755:HTT
uniprot id: A0A2Y9SCD5
uniprot id: A0A2Y9SGW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the huntingtin family.
messages: Cytoplasm
messages: May play a role in microtubule-mediated transport or vesicle function.
messages: Nucleus

9755:NUPR2
gene id: 9755:NUPR2
uniprot id: A0A2Y9EPV6
names: Similarity
messages: Belongs to the NUPR family.

9755:TXLNG
gene id: 9755:TXLNG
uniprot id: A0A2Y9RWU4
uniprot id: A0A455APZ3
uniprot id: A0A455ARV2
uniprot id: A0A455B3N7
names: Similarity
messages: Belongs to the taxilin family.

9755:LTBR
gene id: 9755:LTBR
uniprot id: A0A2Y9EIX9
uniprot id: A0A455BDC6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:LOC102981657
gene id: 9755:LOC102981657
uniprot id: A0A2Y9FQL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

9755:SLC44A3
gene id: 9755:SLC44A3
uniprot id: A0A2Y9EZE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

9755:TP73
gene id: 9755:TP73
uniprot id: A0A455B483
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Found in a complex with p53/TP53 and CABLES1.
messages: Mitochondrion matrix
messages: Nucleus
messages: PML body
messages: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
messages: centrosome

9755:AJAP1
gene id: 9755:AJAP1
uniprot id: A0A2Y9SRS7
names: Subcellular Location Annotation
messages: Membrane

9755:HOOK3
gene id: 9755:HOOK3
uniprot id: A0A2Y9TGG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hook family.
messages: cytoskeleton

9755:LOC112066930
gene id: 9755:LOC112066930
uniprot id: A0A455AP95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the THAP1 family.
messages: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes.
messages: Interacts with PAWR. Component of a THAP1/THAP3-HCFC1-OGT complex that contains, either THAP1 or THAP3, HCFC1 and OGT. Interacts with OGT. Interacts (via the HBM) with HCFC1 (via the Kelch-repeat domain); the interaction recruits HCFC1 to the RRM1 promoter.
messages: nucleoplasm

9755:KAT7
gene id: 9755:KAT7
uniprot id: A0A2Y9FUW4
uniprot id: A0A2Y9T564
uniprot id: A0A2Y9TB34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

9755:IFNB1
gene id: 9755:IFNB1
uniprot id: A0A2Y9FJ90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

9755:ATOH7
gene id: 9755:ATOH7
uniprot id: A0A2Y9TDZ1
names: Subcellular Location Annotation
messages: Nucleus
messages: Perikaryon
messages: axon

9755:ERAL1
gene id: 9755:ERAL1
uniprot id: A0A2Y9FFG7
uniprot id: A0A2Y9T2M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly.

9755:RBM3
gene id: 9755:RBM3
uniprot id: A0A2Y9F5Q2
uniprot id: A0A2Y9F5V3
names: Subcellular Location Annotation
messages: Cytoplasm

9755:AGO2
gene id: 9755:AGO2
uniprot id: A0A2Y9F0R0
uniprot id: A0A2Y9T2J1
uniprot id: A0A2Y9T6G8
uniprot id: A0A2Y9T8Q1
uniprot id: A0A455C823
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argonaute family.
messages: Belongs to the argonaute family. Ago subfamily.
messages: Hydroxylated. 4-hydroxylation appears to enhance protein stability but is not required for miRNA-binding or endonuclease activity.
messages: Interacts with DICER1 through its Piwi domain and with TARBP2 during assembly of the RNA-induced silencing complex (RISC). Together, DICER1, AGO2 and TARBP2 constitute the trimeric RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC). Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. Note however that the term RISC has also been used to describe the trimeric RLC/miRLC. The formation of RISC complexes containing siRNAs rather than miRNAs appears to occur independently of DICER1. Interacts with AGO1. Also interacts with DDB1, DDX5, DDX6, DDX20, DHX30, DHX36, DDX47, DHX9, ELAVL, FXR1, GEMIN4, HNRNPF, IGF2BP1, ILF3, IMP8, MATR3, PABPC1, PRMT5, P4HA1, P4HB, RBM4, SART3, TNRC6A, TNRC6B, UPF1 and YBX1. Interacts with the P-body components DCP1A and XRN1. Associates with polysomes and messenger ribonucleoproteins (mNRPs). Interacts with RBM4; the interaction is modulated under stress-induced conditions, occurs under both cell proliferation and differentiation conditions and in an RNA-and phosphorylation-independent manner. Interacts with LIMD1, WTIP and AJUBA. Interacts with TRIM71. Interacts with APOBEC3G in an RNA-dependent manner. Interacts with APOBEC3A, APOBEC3C, APOBEC3F and APOBEC3H. Interacts with DICER1, TARBP2, EIF6, MOV10 and RPL7A (60S ribosome subunit); they form a large RNA-induced silencing complex (RISC). Interacts with FMR1. Interacts with ZFP36.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the mRNA specifically by AGO2. Binding of RISC to a partially complementary mRNA results in silencing through inhibition of translation, and this is independent of endonuclease activity. May inhibit translation initiation by binding to the 7-methylguanosine cap, thereby preventing the recruitment of the translation initiation factor eIF4-E. May also inhibit translation initiation via interaction with EIF6, which itself binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit. The inhibition of translational initiation leads to the accumulation of the affected mRNA in cytoplasmic processing bodies (P-bodies), where mRNA degradation may subsequently occur. In some cases RISC-mediated translational repression is also observed for miRNAs that perfectly match the 3' untranslated region (3'-UTR). Can also up-regulate the translation of specific mRNAs under certain growth conditions. Binds to the AU element of the 3'-UTR of the TNF (TNF-alpha) mRNA and up-regulates translation under conditions of serum starvation. Also required for transcriptional gene silencing (TGS), in which short RNAs known as antigene RNAs or agRNAs direct the transcriptional repression of complementary promoter regions.
messages: The Piwi domain may perform RNA cleavage by a mechanism similar to that of RNase H. However, while RNase H utilizes a triad of Asp-Asp-Glu (DDE) for metal ion coordination, this protein appears to utilize a triad of Asp-Asp-His (DDH).

9755:LPAR1
gene id: 9755:LPAR1
uniprot id: A0A2Y9T055
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cell surface
messages: Endosome
messages: Membrane

9755:LOC102974182
gene id: 9755:LOC102974182
uniprot id: A0A2Y9FK76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm

9755:TGIF1
gene id: 9755:TGIF1
uniprot id: A0A2Y9FMV5
names: Subcellular Location Annotation
messages: Nucleus

9755:LOC102973323
gene id: 9755:LOC102973323
uniprot id: A0A2Y9EI44
names: Similarity
messages: Belongs to the CD36 family.

9755:ST7
gene id: 9755:ST7
uniprot id: A0A2Y9TAN8
uniprot id: A0A2Y9TEC8
uniprot id: A0A2Y9TED4
uniprot id: A0A455BA26
uniprot id: A0A455BAB5
uniprot id: A0A455BCG4
uniprot id: A0A455BP37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ST7 family.
messages: Membrane

9755:CYRIA
gene id: 9755:CYRIA
uniprot id: A0A2Y9SDZ8
uniprot id: A0A2Y9SFF3
uniprot id: A0A455BUS8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CYRI family.
messages: Interacts with RAC1 (GTP-bound form preferentially).
messages: Membrane

9755:EFHC1
gene id: 9755:EFHC1
uniprot id: A0A2Y9FVG1
uniprot id: A0A455AGF0
names: Subcellular Location Annotation
messages: cilium axoneme

9755:HOXC9
gene id: 9755:HOXC9
uniprot id: A0A2Y9FM40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

9755:RNF8
gene id: 9755:RNF8
uniprot id: A0A2Y9SHA5
uniprot id: A0A2Y9SQ17
uniprot id: A0A455AFQ5
uniprot id: A0A455AH18
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: According to a well-established model, RNF8 initiate H2A 'Lys-63'-linked ubiquitination leading to recruitment of RNF168 to amplify H2A 'Lys-63'-linked ubiquitination. However, other data suggest that RNF168 is the priming ubiquitin ligase by mediating monoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histone H2A (H2AK13Ub and H2AK15Ub respectively). These data suggest that RNF168 might be recruited to DSBs sites in a RNF8-dependent manner by binding to non-histone proteins ubiquitinated via 'Lys-63'-linked and initiates monoubiquitination of H2A, which is then amplified by RNF8. Additional evidences are however required to confirm these data.
messages: Autoubiquitinated through 'Lys-48' and 'Lys-63' of ubiquitin. 'Lys-63' polyubiquitination is mediated by UBE2N. 'Lys-29'-type polyubiquitination is also observed, but it doesn't require its own functional RING-type zinc finger.
messages: Belongs to the CHFR family.
messages: Belongs to the RNF8 family.
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53BP1 and BRCA1 ionizing radiation-induced foci (IRIF). Also controls the recruitment of UIMC1-BRCC3 (RAP80-BRCC36) and PAXIP1/PTIP to DNA damage sites. Also recruited at DNA interstrand cross-links (ICLs) sites and catalyzes 'Lys-63'-linked ubiquitination of histones H2A and H2AX, leading to recruitment of FAAP20 and Fanconi anemia (FA) complex, followed by interstrand cross-link repair. H2A ubiquitination also mediates the ATM-dependent transcriptional silencing at regions flanking DSBs in cis, a mechanism to avoid collision between transcription and repair intermediates. Promotes the formation of 'Lys-63'-linked polyubiquitin chains via interactions with the specific ubiquitin-conjugating UBE2N/UBC13 and ubiquitinates non-histone substrates such as PCNA. Substrates that are polyubiquitinated at 'Lys-63' are usually not targeted for degradation. Also catalyzes the formation of 'Lys-48'-linked polyubiquitin chains via interaction with the ubiquitin-conjugating UBE2L6/UBCH8, leading to degradation of substrate proteins such as CHEK2, JMJD2A/KDM4A and KU80/XRCC5: it is still unclear how the preference toward 'Lys-48'- versus 'Lys-63'-linked ubiquitination is regulated but it could be due to RNF8 ability to interact with specific E2 specific ligases. For instance, interaction with phosphorylated HERC2 promotes the association between RNF8 and UBE2N/UBC13 and favors the specific formation of 'Lys-63'-linked ubiquitin chains…
messages: Homodimer. Forms a E2-E3 ubiquitin ligase complex composed of the RNF8 homodimer and a E2 heterodimer of UBE2N and UBE2V2. Interacts with class III E2s, including UBE2E1, UBE2E2, and UBE2E3 and with UBE2N. Interacts with RXRA. Interacts (via FHA domain) with phosphorylated HERC2 (via C-terminus). Interacts with PIWIL1; leading to sequester RNF8 in the cytoplasm.
messages: Midbody
messages: Nucleus
messages: The FHA domain specifically recognizes and binds ATM-phosphorylated MDC1 and phosphorylated HERC2.
messages: telomere

9755:UTP6
gene id: 9755:UTP6
uniprot id: A0A2Y9SZK4
uniprot id: A0A2Y9T617
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP6 family.
messages: nucleolus

9755:LOC102977145
gene id: 9755:LOC102977145
uniprot id: A0A2Y9EMT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOR1AIP family.
messages: Membrane

9755:LBX2
gene id: 9755:LBX2
uniprot id: A0A2Y9ETC8
names: Subcellular Location Annotation
messages: Nucleus

9755:MANF
gene id: 9755:MANF
uniprot id: A0A455AIT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARMET family.
messages: Secreted

9755:GRAMD1C
gene id: 9755:GRAMD1C
uniprot id: A0A455BK61
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:DDX24
gene id: 9755:DDX24
uniprot id: A0A455BWJ0
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

9755:SUCLG1
gene id: 9755:SUCLG1
uniprot id: A0A2Y9F9Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterodimer of an alpha and a beta subunit. Different beta subunits determine nucleotide specificity. Together with the ATP-specific beta subunit SUCLA2, forms an ADP-forming succinyl-CoA synthetase (A-SCS). Together with the GTP-specific beta subunit SUCLG2 forms a GDP-forming succinyl-CoA synthetase (G-SCS).
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.

9755:TRPC7
gene id: 9755:TRPC7
uniprot id: A0A2Y9SQY4
names: Subcellular Location Annotation
messages: Membrane

9755:SEMA7A
gene id: 9755:SEMA7A
uniprot id: A0A2Y9T141
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:HOXD3
gene id: 9755:HOXD3
uniprot id: A0A2Y9SNQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

9755:SLC9A6
gene id: 9755:SLC9A6
uniprot id: A0A2Y9EEA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Endosome membrane
messages: Recycling endosome membrane

9755:ALOX5
gene id: 9755:ALOX5
uniprot id: A0A455AP74
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:TAS1R1
gene id: 9755:TAS1R1
uniprot id: A0A2Y9SS29
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9755:LOC102977405
gene id: 9755:LOC102977405
uniprot id: A0A2Y9FF89
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

9755:HDAC2
gene id: 9755:HDAC2
uniprot id: A0A2Y9RXT7
uniprot id: A0A455BNM3
uniprot id: A0A455BR80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

9755:VANGL2
gene id: 9755:VANGL2
uniprot id: A0A2Y9FSD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

9755:CHST1
gene id: 9755:CHST1
uniprot id: A0A2Y9FID4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

9755:SLC16A7
gene id: 9755:SLC16A7
uniprot id: A0A2Y9EZS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

9755:ENAH
gene id: 9755:ENAH
uniprot id: A0A2Y9T647
uniprot id: A0A2Y9T7X2
uniprot id: A0A2Y9TC40
uniprot id: A0A2Y9TC43
uniprot id: A0A2Y9TE66
uniprot id: A0A2Y9TE71
uniprot id: A0A455B5G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ena/VASP family.
messages: cytoskeleton

9755:SHOX
gene id: 9755:SHOX
uniprot id: A0A2Y9RY93
names: Subcellular Location Annotation
messages: Nucleus

9755:CDK5RAP2
gene id: 9755:CDK5RAP2
uniprot id: A0A455BKX5
names: Subcellular Location Annotation
messages: Golgi apparatus
messages: centrosome

9755:LOC102981944
gene id: 9755:LOC102981944
uniprot id: A0A2Y9FSH5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9755:LOC102973494
gene id: 9755:LOC102973494
uniprot id: A0A2Y9SA50
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

9755:LOC102978731
gene id: 9755:LOC102978731
uniprot id: A0A455AFA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tigger transposable element derived protein family.
messages: Nucleus

9755:RGR
gene id: 9755:RGR
uniprot id: A0A2Y9EJJ3
names: Subcellular Location Annotation
messages: Membrane

9755:PLXNA3
gene id: 9755:PLXNA3
uniprot id: A0A2Y9S1Q9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:WNT9B
gene id: 9755:WNT9B
uniprot id: A0A2Y9FKN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9755:PTK2B
gene id: 9755:PTK2B
uniprot id: A0A2Y9T8K9
uniprot id: A0A455BMQ4
uniprot id: A0A455C238
names: Subcellular Location Annotation
messages: Cell membrane
messages: cell cortex
messages: focal adhesion

9755:ECHDC2
gene id: 9755:ECHDC2
uniprot id: A0A2Y9EUY7
uniprot id: A0A455BB50
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

9755:FMNL3
gene id: 9755:FMNL3
uniprot id: A0A455BEB2
names: Similarity
messages: Belongs to the formin homology family.

9755:CILP2
gene id: 9755:CILP2
uniprot id: A0A2Y9F869
names: Subcellular Location Annotation
messages: extracellular matrix

9755:HEPH
gene id: 9755:HEPH
uniprot id: A0A2Y9S4L0
uniprot id: A0A2Y9S929
names: Similarity
messages: Belongs to the multicopper oxidase family.

9755:ALKAL2
gene id: 9755:ALKAL2
uniprot id: A0A2Y9SAF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALKAL family.
messages: Secreted

9755:RRP1B
gene id: 9755:RRP1B
uniprot id: A0A2Y9SBB5
uniprot id: A0A2Y9SF14
uniprot id: A0A2Y9SI12
uniprot id: A0A455BI53
names: Similarity
messages: Belongs to the RRP1 family.

9755:ZSCAN10
gene id: 9755:ZSCAN10
uniprot id: A0A2Y9ECU4
names: Subcellular Location Annotation
messages: Nucleus

9755:ADORA2A
gene id: 9755:ADORA2A
uniprot id: A0A2Y9FPT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

9755:RANBP6
gene id: 9755:RANBP6
uniprot id: A0A2Y9ETR5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9755:TMEM200B
gene id: 9755:TMEM200B
uniprot id: A0A2Y9SW07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

9755:LMNB2
gene id: 9755:LMNB2
uniprot id: A0A2Y9TIL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intermediate filament family.
messages: Nucleus lamina

9755:SLC26A8
gene id: 9755:SLC26A8
uniprot id: A0A455AGB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

9755:IL22RA2
gene id: 9755:IL22RA2
uniprot id: A0A2Y9FU46
names: Subcellular Location Annotation
messages: Membrane

9755:TNFRSF1A
gene id: 9755:TNFRSF1A
uniprot id: A0A2Y9TAJ9
uniprot id: A0A455BSA5
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:LOC102990369
gene id: 9755:LOC102990369
uniprot id: A0A2Y9T858
names: Similarity
messages: Belongs to the intermediate filament family.

9755:TYW3
gene id: 9755:TYW3
uniprot id: A0A2Y9FHQ1
uniprot id: A0A2Y9FI47
names: Function
names: Similarity
messages: Belongs to the TYW3 family.
messages: Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.

9755:SLC17A4
gene id: 9755:SLC17A4
uniprot id: A0A2Y9FQM9
names: Subcellular Location Annotation
messages: Membrane

9755:CEP44
gene id: 9755:CEP44
uniprot id: A0A455BM36
uniprot id: A0A455BMT8
uniprot id: A0A455BQD9
uniprot id: A0A455C278
names: Subcellular Location Annotation
messages: Midbody
messages: centriole
messages: spindle pole

9755:DOHH
gene id: 9755:DOHH
uniprot id: A0A455CBE3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the deoxyhypusine hydroxylase family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.

9755:ITGB1
gene id: 9755:ITGB1
uniprot id: A0A2Y9F676
uniprot id: A0A455BRX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Melanosome
messages: Membrane
messages: Recycling endosome
messages: focal adhesion
messages: invadopodium membrane
messages: lamellipodium
messages: ruffle membrane

9755:KCNF1
gene id: 9755:KCNF1
uniprot id: A0A2Y9S7U7
names: Subcellular Location Annotation
messages: Membrane

9755:LOC102991858
gene id: 9755:LOC102991858
uniprot id: A0A455ADA4
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9755:SIRT4
gene id: 9755:SIRT4
uniprot id: A0A2Y9FW31
uniprot id: A0A455AI99
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: According to some authors, ADP-ribosyltransferase activity of sirtuins may be an inefficient side reaction of the deacetylase activity and may not be physiologically relevant.
messages: Acts as NAD-dependent protein lipoamidase, biotinylase, deacetylase and ADP-ribosyl transferase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP-ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitochondrial glutamine metabolism by mediating mono ADP-ribosylation of GLUD1: expressed in response to DNA damage and negatively regulates anaplerosis by inhibiting GLUD1, leading to block metabolism of glutamine into tricarboxylic acid cycle and promoting cell cycle arrest. In response to mTORC1 signal, SIRT4 expression is repressed, promoting anaplerosis and cell proliferation. Acts as a tumor suppressor. Also acts as a NAD-dependent protein deacetylase: mediates deacetylation of 'Lys-471' of MLYCD, inhibiting its activity, thereby acting as a regulator of lipid homeostasis. Does not seem to deacetylate PC. Controls fatty acid oxidation by inhibiting PPARA transcriptional activation. Impairs SIRT1-PPARA interaction probably through the regulation of NAD(+) levels. Down-regulates insulin secretion.
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Interacts with GLUD1, IDE and SLC25A5. Interacts with DLAT and PDHX.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion matrix

9755:SUPT16H
gene id: 9755:SUPT16H
uniprot id: A0A2Y9EM36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24 family. SPT16 subfamily.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Component of the FACT complex.
messages: Nucleus

9755:RELN
gene id: 9755:RELN
uniprot id: A0A2Y9S6D6
uniprot id: A0A2Y9S785
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the reelin family.
messages: Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Oligomer of disulfide-linked homodimers. Binds to the ectodomains of VLDLR and LRP8/APOER2.
messages: extracellular matrix

9755:LOC114484233
gene id: 9755:LOC114484233
uniprot id: A0A455AGL1
names: Similarity
messages: Belongs to the VPS52 family.

9755:LOC102979418
gene id: 9755:LOC102979418
uniprot id: A0A2Y9SQK5
names: Subcellular Location Annotation
messages: Nucleus

9755:STT3A
gene id: 9755:STT3A
uniprot id: A0A2Y9EPL9
uniprot id: A0A2Y9T9I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

9755:TMEM94
gene id: 9755:TMEM94
uniprot id: A0A455BYM1
uniprot id: A0A455BYM8
uniprot id: A0A455BZL5
uniprot id: A0A455BZM3
uniprot id: A0A455C2J9
uniprot id: A0A455CA67
names: Subcellular Location Annotation
messages: Membrane

9755:LHX8
gene id: 9755:LHX8
uniprot id: A0A2Y9F546
names: Subcellular Location Annotation
messages: Nucleus

9755:FYN
gene id: 9755:FYN
uniprot id: A0A2Y9S551
uniprot id: A0A2Y9S5U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

9755:FAM171B
gene id: 9755:FAM171B
uniprot id: A0A2Y9F3Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

9755:NOP58
gene id: 9755:NOP58
uniprot id: A0A2Y9F9I8
uniprot id: A0A2Y9F9V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

9755:DOCK6
gene id: 9755:DOCK6
uniprot id: A0A2Y9TGA0
uniprot id: A0A2Y9TJL7
names: Similarity
messages: Belongs to the DOCK family.

9755:DPP4
gene id: 9755:DPP4
uniprot id: A0A2Y9EMH4
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the peptidase S9B family. DPPIV subfamily.
messages: Cell junction
messages: Cell membrane
messages: Membrane raft
messages: invadopodium membrane
messages: lamellipodium membrane

9755:LOC102992843
gene id: 9755:LOC102992843
uniprot id: A0A2Y9EPL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9755:LOC112063878
gene id: 9755:LOC112063878
uniprot id: A0A2Y9SBC3
names: Subcellular Location Annotation
messages: nucleolus

9755:LGSN
gene id: 9755:LGSN
uniprot id: A0A2Y9FIS9
names: Similarity
messages: Belongs to the glutamine synthetase family.

9755:DHDDS
gene id: 9755:DHDDS
uniprot id: A0A2Y9F084
names: Similarity
messages: Belongs to the UPP synthase family.

9755:TTYH3
gene id: 9755:TTYH3
uniprot id: A0A2Y9SML7
uniprot id: A0A2Y9SV00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

9755:LOC102979483
gene id: 9755:LOC102979483
uniprot id: A0A2Y9RXC9
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.

9755:SIVA1
gene id: 9755:SIVA1
uniprot id: A0A2Y9T932
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl-x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.
messages: Nucleus

9755:MYO1F
gene id: 9755:MYO1F
uniprot id: A0A2Y9EV90
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

9755:LOC114487494
gene id: 9755:LOC114487494
uniprot id: A0A455BX12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

9755:BIRC2
gene id: 9755:BIRC2
uniprot id: A0A2Y9FG71
uniprot id: A0A455C944
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IAP family.
messages: Cytoplasm
messages: Nucleus

9755:EPHA1
gene id: 9755:EPHA1
uniprot id: A0A455B921
names: Subcellular Location Annotation
messages: Membrane

9755:OGG1
gene id: 9755:OGG1
uniprot id: A0A2Y9FFQ6
uniprot id: A0A2Y9FFR1
uniprot id: A0A2Y9FFZ2
uniprot id: A0A2Y9FFZ8
uniprot id: A0A455AG28
uniprot id: A0A455AGH6
uniprot id: A0A455AGI8
uniprot id: A0A455AHV7
uniprot id: A0A455AIA1
uniprot id: A0A455AIA7
uniprot id: A0A455AU34
uniprot id: A0A455AU43
uniprot id: A0A455AU48
names: Function
names: Similarity
messages: Belongs to the type-1 OGG1 family.
messages: DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion.

9755:DNAH5
gene id: 9755:DNAH5
uniprot id: A0A455BXS7
names: Similarity
messages: Belongs to the dynein heavy chain family.

9755:RFC1
gene id: 9755:RFC1
uniprot id: A0A2Y9S1X9
uniprot id: A0A2Y9S8N0
uniprot id: A0A2Y9S9Z7
uniprot id: A0A455BFX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the activator 1 large subunit family.
messages: Nucleus

9755:NPEPL1
gene id: 9755:NPEPL1
uniprot id: A0A2Y9T5X6
uniprot id: A0A455C1U5
names: Similarity
messages: Belongs to the peptidase M17 family.

9755:LOC102993079
gene id: 9755:LOC102993079
uniprot id: A0A2Y9SN75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:PKNOX1
gene id: 9755:PKNOX1
uniprot id: A0A2Y9SJM8
uniprot id: A0A2Y9SJN4
uniprot id: A0A455BHQ1
uniprot id: A0A455BXF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

9755:GINS4
gene id: 9755:GINS4
uniprot id: A0A2Y9FMQ6
uniprot id: A0A2Y9FN81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GINS4/SLD5 family.
messages: Chromosome
messages: Nucleus
messages: Required for initiation of chromosomal DNA replication. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.

9755:ZUP1
gene id: 9755:ZUP1
uniprot id: A0A2Y9FD05
uniprot id: A0A455C310
names: Similarity
names: Subunit
messages: Belongs to the peptidase C78 family. ZUFSP subfamily.
messages: Interacts with RPA1 and RPA2.

9755:MGME1
gene id: 9755:MGME1
uniprot id: A0A2Y9EWD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGME1 family.
messages: Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA-primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair.
messages: Mitochondrion

9755:AP1S3
gene id: 9755:AP1S3
uniprot id: A0A2Y9SQ49
uniprot id: A0A2Y9SXD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: Membrane
messages: clathrin-coated pit

9755:PIK3IP1
gene id: 9755:PIK3IP1
uniprot id: A0A455AIN9
uniprot id: A0A455AKK2
uniprot id: A0A455AKK9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:ZDHHC13
gene id: 9755:ZDHHC13
uniprot id: A0A2Y9FBC4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9755:PLK1
gene id: 9755:PLK1
uniprot id: A0A2Y9EPA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
messages: Midbody
messages: Nucleus
messages: centrosome

9755:ZC3HC1
gene id: 9755:ZC3HC1
uniprot id: A0A2Y9EUE1
uniprot id: A0A2Y9T8W0
uniprot id: A0A2Y9TGL8
names: Subcellular Location Annotation
messages: Nucleus

9755:SLC25A48
gene id: 9755:SLC25A48
uniprot id: A0A2Y9EGF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9755:KCNJ11
gene id: 9755:KCNJ11
uniprot id: A0A455C9U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ11 subfamily.
messages: Membrane

9755:SLC9A2
gene id: 9755:SLC9A2
uniprot id: A0A2Y9S189
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Interacts with CHP1 and CHP2.
messages: Membrane

9755:HOMEZ
gene id: 9755:HOMEZ
uniprot id: A0A2Y9EDK4
uniprot id: A0A2Y9EEN7
uniprot id: A0A2Y9EFB4
names: Subcellular Location Annotation
messages: Nucleus

9755:ASPM
gene id: 9755:ASPM
uniprot id: A0A2Y9TED1
names: Subcellular Location Annotation
messages: Nucleus

9755:ABCB5
gene id: 9755:ABCB5
uniprot id: A0A2Y9TGE0
names: Subcellular Location Annotation
messages: Membrane

9755:SNCA
gene id: 9755:SNCA
uniprot id: A0A2Y9SUS1
uniprot id: A0A2Y9T2V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synuclein family.
messages: Membrane
messages: Nucleus
messages: Secreted
messages: Synapse
messages: axon

9755:GABRG2
gene id: 9755:GABRG2
uniprot id: A0A2Y9FB04
uniprot id: A0A2Y9FD09
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRG2 sub-subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9755:ITGAV
gene id: 9755:ITGAV
uniprot id: A0A455AUW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9755:ACADM
gene id: 9755:ACADM
uniprot id: A0A2Y9EQN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Mitochondrion matrix

9755:TFAP2D
gene id: 9755:TFAP2D
uniprot id: A0A2Y9EHJ0
names: Similarity
messages: Belongs to the AP-2 family.

9755:DDX47
gene id: 9755:DDX47
uniprot id: A0A2Y9T230
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

9755:CHDH
gene id: 9755:CHDH
uniprot id: A0A2Y9SQJ8
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

9755:SESN1
gene id: 9755:SESN1
uniprot id: A0A2Y9EED7
uniprot id: A0A2Y9EFJ0
uniprot id: A0A455BN88
uniprot id: A0A455BRD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

9755:SULT1C4
gene id: 9755:SULT1C4
uniprot id: A0A2Y9EIS3
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9755:IL17A
gene id: 9755:IL17A
uniprot id: A0A2Y9F315
uniprot id: A0A2Y9SHC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

9755:PEX5L
gene id: 9755:PEX5L
uniprot id: A0A2Y9SMS7
uniprot id: A0A2Y9SMT1
uniprot id: A0A2Y9SNQ7
uniprot id: A0A2Y9SR80
uniprot id: A0A2Y9STX8
uniprot id: A0A2Y9SW05
names: Similarity
messages: Belongs to the peroxisomal targeting signal receptor family.

9755:RYBP
gene id: 9755:RYBP
uniprot id: A0A2Y9SQA3
uniprot id: A0A455ADE0
names: Subcellular Location Annotation
messages: Nucleus

9755:LOC102988052
gene id: 9755:LOC102988052
uniprot id: A0A455BYE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

9755:NPBWR1
gene id: 9755:NPBWR1
uniprot id: A0A2Y9SXG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9755:RPN1
gene id: 9755:RPN1
uniprot id: A0A2Y9FUQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

9755:SFRP2
gene id: 9755:SFRP2
uniprot id: A0A2Y9FAG3
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:WDR76
gene id: 9755:WDR76
uniprot id: A0A2Y9RYI3
uniprot id: A0A2Y9RYJ7
uniprot id: A0A2Y9RYK4
uniprot id: A0A2Y9S5C6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: Interacts with CUL4A and/or CUL4B.
messages: Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

9755:TTC39A
gene id: 9755:TTC39A
uniprot id: A0A2Y9F3L0
uniprot id: A0A2Y9SEF6
uniprot id: A0A455B8T0
names: Similarity
messages: Belongs to the TTC39 family.

9755:RPTOR
gene id: 9755:RPTOR
uniprot id: A0A455C240
uniprot id: A0A455C5D0
names: Similarity
messages: Belongs to the WD repeat RAPTOR family.

9755:ZFP36L1
gene id: 9755:ZFP36L1
uniprot id: A0A2Y9SE72
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

9755:ATP5F1B
gene id: 9755:ATP5F1B
uniprot id: A0A2Y9FUP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

9755:ETV1
gene id: 9755:ETV1
uniprot id: A0A2Y9ELU5
uniprot id: A0A2Y9EM92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9755:UBE2L3
gene id: 9755:UBE2L3
uniprot id: A0A2Y9SK87
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9755:STRN3
gene id: 9755:STRN3
uniprot id: A0A2Y9TKQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

9755:SOAT1
gene id: 9755:SOAT1
uniprot id: A0A2Y9EU28
uniprot id: A0A2Y9TKF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:IRAK1BP1
gene id: 9755:IRAK1BP1
uniprot id: A0A2Y9FNZ7
uniprot id: A0A455BNE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRAK1BP1 family.
messages: Cytoplasm
messages: Nucleus

9755:CEP76
gene id: 9755:CEP76
uniprot id: A0A2Y9EM66
uniprot id: A0A2Y9SDT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP76 family.
messages: Centrosomal protein involved in regulation of centriole duplication. Required to limit centriole duplication to once per cell cycle by preventing centriole reduplication.
messages: centriole

9755:NDUFV2
gene id: 9755:NDUFV2
uniprot id: A0A2Y9F631
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.

9755:GJA3
gene id: 9755:GJA3
uniprot id: A0A2Y9SU90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9755:BAZ1A
gene id: 9755:BAZ1A
uniprot id: A0A2Y9SD44
names: Subcellular Location Annotation
messages: Nucleus

9755:SZRD1
gene id: 9755:SZRD1
uniprot id: A0A455B4Y7
names: Similarity
messages: Belongs to the SZRD1 family.

9755:GATAD1
gene id: 9755:GATAD1
uniprot id: A0A2Y9TGU8
names: Subcellular Location Annotation
messages: Nucleus

9755:LOC112065494
gene id: 9755:LOC112065494
uniprot id: A0A2Y9T219
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:LOC102989537
gene id: 9755:LOC102989537
uniprot id: A0A2Y9EPH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

9755:HNRNPAB
gene id: 9755:HNRNPAB
uniprot id: A0A2Y9S076
uniprot id: A0A2Y9S097
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9755:CCL28
gene id: 9755:CCL28
uniprot id: A0A2Y9FDF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

9755:SENP1
gene id: 9755:SENP1
uniprot id: A0A2Y9ELB1
uniprot id: A0A2Y9EM26
uniprot id: A0A2Y9SJH6
names: Similarity
messages: Belongs to the peptidase C48 family.

9755:THAP10
gene id: 9755:THAP10
uniprot id: A0A2Y9EJ19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the THAP1 family.
messages: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes.
messages: Interacts with PAWR. Component of a THAP1/THAP3-HCFC1-OGT complex that contains, either THAP1 or THAP3, HCFC1 and OGT. Interacts with OGT. Interacts (via the HBM) with HCFC1 (via the Kelch-repeat domain); the interaction recruits HCFC1 to the RRM1 promoter.
messages: nucleoplasm

9755:TMOD3
gene id: 9755:TMOD3
uniprot id: A0A455BT04
names: Subcellular Location Annotation
messages: cytoskeleton

9755:CENPU
gene id: 9755:CENPU
uniprot id: A0A2Y9S3G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-U/AME1 family.
messages: Nucleus

9755:NAP1L2
gene id: 9755:NAP1L2
uniprot id: A0A2Y9FGA4
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9755:RER1
gene id: 9755:RER1
uniprot id: A0A2Y9SXZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RER1 family.
messages: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
messages: Membrane

9755:NANOS3
gene id: 9755:NANOS3
uniprot id: A0A455C1A5
names: Similarity
messages: Belongs to the nanos family.

9755:ATPSCKMT
gene id: 9755:ATPSCKMT
uniprot id: A0A2Y9EQ16
uniprot id: A0A2Y9SC48
uniprot id: A0A455BXS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANT/ATPSC lysine N-methyltransferase family.
messages: Mitochondrion membrane

9755:NSMCE1
gene id: 9755:NSMCE1
uniprot id: A0A2Y9FJF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE1 family.
messages: Component of the Smc5-Smc6 complex.
messages: Nucleus
messages: RING-type zinc finger-containing E3 ubiquitin ligase that assembles with melanoma antigen protein (MAGE) to catalyze the direct transfer of ubiquitin from E2 ubiquitin-conjugating enzyme to a specific substrate. Involved in maintenance of genome integrity, DNA damage response and DNA repair.
messages: telomere

9755:CDPF1
gene id: 9755:CDPF1
uniprot id: A0A2Y9SW88
names: Similarity
messages: Belongs to the CDPF1 family.

9755:LOC102992416
gene id: 9755:LOC102992416
uniprot id: A0A2Y9SIA5
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

9755:SPPL3
gene id: 9755:SPPL3
uniprot id: A0A2Y9SJM6
uniprot id: A0A455AJS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

9755:HSD17B1
gene id: 9755:HSD17B1
uniprot id: A0A2Y9EI50
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9755:GALNT10
gene id: 9755:GALNT10
uniprot id: A0A2Y9SCN3
uniprot id: A0A455BJN5
uniprot id: A0A455BMU0
uniprot id: A0A455BZI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9755:TCF7L2
gene id: 9755:TCF7L2
uniprot id: A0A2Y9SEH4
uniprot id: A0A2Y9SEI4
uniprot id: A0A2Y9SEJ0
uniprot id: A0A2Y9SFD9
uniprot id: A0A2Y9SFF2
uniprot id: A0A2Y9SI93
uniprot id: A0A2Y9SI97
uniprot id: A0A2Y9SIA1
uniprot id: A0A2Y9SIA4
uniprot id: A0A2Y9SIA8
uniprot id: A0A2Y9SL55
uniprot id: A0A2Y9SL59
uniprot id: A0A2Y9SL69
uniprot id: A0A2Y9SMW9
uniprot id: A0A2Y9SMX5
uniprot id: A0A2Y9SMY1
uniprot id: A0A2Y9SMY6
uniprot id: A0A455AMJ8
uniprot id: A0A455AMK2
uniprot id: A0A455AMK7
uniprot id: A0A455AMR6
uniprot id: A0A455AMS0
uniprot id: A0A455AMS7
uniprot id: A0A455AP90
uniprot id: A0A455AP99
uniprot id: A0A455APK5
uniprot id: A0A455APL1
uniprot id: A0A455B1B9
uniprot id: A0A455B1C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

9755:CTNNBL1
gene id: 9755:CTNNBL1
uniprot id: A0A2Y9T7L8
uniprot id: A0A455C264
uniprot id: A0A455CA41
names: Subcellular Location Annotation
messages: Nucleus

9755:TPH1
gene id: 9755:TPH1
uniprot id: A0A2Y9F9Z0
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

9755:UNC45A
gene id: 9755:UNC45A
uniprot id: A0A2Y9ETI4
uniprot id: A0A2Y9EUU9
names: Subcellular Location Annotation
messages: perinuclear region

9755:API5
gene id: 9755:API5
uniprot id: A0A2Y9FLY0
uniprot id: A0A2Y9FMC8
names: Similarity
messages: Belongs to the API5 family.

9755:WNT3
gene id: 9755:WNT3
uniprot id: A0A2Y9TB72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9755:CHPT1
gene id: 9755:CHPT1
uniprot id: A0A2Y9T0W0
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

9755:AGL
gene id: 9755:AGL
uniprot id: A0A455BAA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycogen debranching enzyme family.
messages: Cytoplasm
messages: Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.

9755:NCBP1
gene id: 9755:NCBP1
uniprot id: A0A2Y9EWZ7
uniprot id: A0A2Y9EY00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NCBP1 family.
messages: Nucleus

9755:PAPSS1
gene id: 9755:PAPSS1
uniprot id: A0A2Y9EFL1
uniprot id: A0A2Y9S9K7
names: Similarity
messages: In the C-terminal section; belongs to the sulfate adenylyltransferase family.
messages: In the N-terminal section; belongs to the APS kinase family.

9755:LOC102977781
gene id: 9755:LOC102977781
uniprot id: A0A2Y9FIC7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:PIH1D2
gene id: 9755:PIH1D2
uniprot id: A0A2Y9FPX0
uniprot id: A0A2Y9FRV0
uniprot id: A0A455C7I5
names: Similarity
messages: Belongs to the PIH1 family.

9755:FAM124B
gene id: 9755:FAM124B
uniprot id: A0A2Y9FR30
names: Similarity
messages: Belongs to the FAM124 family.

9755:MCHR1
gene id: 9755:MCHR1
uniprot id: A0A2Y9FBW2
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Interacts with NCDN.
messages: Membrane

9755:TNFRSF25
gene id: 9755:TNFRSF25
uniprot id: A0A455BIV4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:LOC102977326
gene id: 9755:LOC102977326
uniprot id: A0A2Y9ER21
names: Similarity
messages: Belongs to the peptidase A1 family.

9755:TLX2
gene id: 9755:TLX2
uniprot id: A0A2Y9ERF9
names: Subcellular Location Annotation
messages: Nucleus

9755:DYNC1H1
gene id: 9755:DYNC1H1
uniprot id: A0A2Y9FFN9
names: Similarity
messages: Belongs to the dynein heavy chain family.

9755:INSM1
gene id: 9755:INSM1
uniprot id: A0A2Y9SNQ0
names: Subcellular Location Annotation
messages: Nucleus

9755:UFL1
gene id: 9755:UFL1
uniprot id: A0A2Y9FF61
uniprot id: A0A455BNY4
names: Similarity
messages: Belongs to the UFL1 family.

9755:TMEM63B
gene id: 9755:TMEM63B
uniprot id: A0A2Y9ESX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

9755:LOC112064364
gene id: 9755:LOC112064364
uniprot id: A0A2Y9SNG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:LSM12
gene id: 9755:LSM12
uniprot id: A0A2Y9T502
names: Similarity
messages: Belongs to the LSM12 family.

9755:SNX3
gene id: 9755:SNX3
uniprot id: A0A2Y9FBM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome
messages: Endosome
messages: phagosome

9755:LOC102984399
gene id: 9755:LOC102984399
uniprot id: A0A2Y9EXR1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Basal cell membrane
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
messages: Interacts with PDZK1.

9755:RBP7
gene id: 9755:RBP7
uniprot id: A0A2Y9EWE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm

9755:ACOT6
gene id: 9755:ACOT6
uniprot id: A0A2Y9S6K1
uniprot id: A0A455BT84
uniprot id: A0A455BVX8
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

9755:HSPA9
gene id: 9755:HSPA9
uniprot id: A0A2Y9F0W7
names: Similarity
messages: Belongs to the heat shock protein 70 family.

9755:SMIM14
gene id: 9755:SMIM14
uniprot id: A0A2Y9F2F8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

9755:LOC102978947
gene id: 9755:LOC102978947
uniprot id: A0A2Y9FT99
uniprot id: A0A455ATM3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9755:MASP2
gene id: 9755:MASP2
uniprot id: A0A2Y9SZ81
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:SCG2
gene id: 9755:SCG2
uniprot id: A0A2Y9EUT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Interacts with Secretogranin III/SCG3.
messages: Neuroendocrine protein of the granin family that regulates the biogenesis of secretory granules.
messages: Secreted

9755:FBN2
gene id: 9755:FBN2
uniprot id: A0A2Y9SFP0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fibrillin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9755:KIF18A
gene id: 9755:KIF18A
uniprot id: A0A2Y9FET8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9755:CIBAR1
gene id: 9755:CIBAR1
uniprot id: A0A2Y9RZ72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CIBAR family.
messages: centriole
messages: cilium basal body

9755:C5
gene id: 9755:C5
uniprot id: A0A2Y9FIB4
names: Subcellular Location Annotation
messages: Secreted

9755:ZNF197
gene id: 9755:ZNF197
uniprot id: A0A2Y9TAU5
uniprot id: A0A455AT76
names: Subcellular Location Annotation
messages: Nucleus

9755:LOC102984452
gene id: 9755:LOC102984452
uniprot id: A0A455ALC7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:PLPP5
gene id: 9755:PLPP5
uniprot id: A0A2Y9TGC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

9755:RIDA
gene id: 9755:RIDA
uniprot id: A0A2Y9EFQ3
uniprot id: A0A455C493
uniprot id: A0A455C4I9
uniprot id: A0A455C8E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RutC family.
messages: Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase.
messages: Peroxisome

9755:TPD52
gene id: 9755:TPD52
uniprot id: A0A2Y9FI63
uniprot id: A0A2Y9T1Q5
uniprot id: A0A455CB95
names: Similarity
messages: Belongs to the TPD52 family.

9755:HINT2
gene id: 9755:HINT2
uniprot id: A0A2Y9EUM3
uniprot id: A0A2Y9SVG8
uniprot id: A0A455BKW4
uniprot id: A0A455BLL0
uniprot id: A0A455C0V8
names: Caution
names: Similarity
messages: Belongs to the HINT family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:CTSS
gene id: 9755:CTSS
uniprot id: A0A455B7A0
uniprot id: A0A455BL94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

9755:FANCC
gene id: 9755:FANCC
uniprot id: A0A2Y9TIB0
uniprot id: A0A2Y9TJ80
uniprot id: A0A455BLR4
uniprot id: A0A455BM00
uniprot id: A0A455BQ03
uniprot id: A0A455C1U6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the multisubunit FA complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. This complex may also include HSP70.
messages: DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.
messages: Nucleus

9755:TES
gene id: 9755:TES
uniprot id: A0A2Y9FUC9
uniprot id: A0A2Y9T0D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prickle / espinas / testin family.
messages: Cytoplasm
messages: Interacts via LIM domain 1 with ZYX. Interacts (via LIM domain 3) with ENAH and VASP. Interacts with ALKBH4, talin, actin, alpha-actinin, GRIP1 and PXN (By similarity). Interacts (via LIM domain 2) with ACTL7A (via N-terminus). Heterodimer with ACTL7A; the heterodimer interacts with ENAH to form a heterotrimer.
messages: Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor.
messages: focal adhesion

9755:CHGB
gene id: 9755:CHGB
uniprot id: A0A2Y9FJR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

9755:ARMC1
gene id: 9755:ARMC1
uniprot id: A0A2Y9T3N0
names: Function
names: Subcellular Location Annotation
messages: In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.
messages: Membrane
messages: Mitochondrion outer membrane

9755:LOC102989827
gene id: 9755:LOC102989827
uniprot id: A0A2Y9SL75
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

9755:DAD1
gene id: 9755:DAD1
uniprot id: A0A2Y9EDR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DAD/OST2 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

9755:CTSZ
gene id: 9755:CTSZ
uniprot id: A0A2Y9T7Y6
names: Similarity
messages: Belongs to the peptidase C1 family.

9755:FOXN4
gene id: 9755:FOXN4
uniprot id: A0A2Y9FS40
names: Subcellular Location Annotation
messages: Nucleus

9755:NME3
gene id: 9755:NME3
uniprot id: A0A2Y9SLK8
names: Similarity
messages: Belongs to the NDK family.

9755:DNAH8
gene id: 9755:DNAH8
uniprot id: A0A2Y9SQ69
names: Similarity
messages: Belongs to the dynein heavy chain family.

9755:LPAR6
gene id: 9755:LPAR6
uniprot id: A0A2Y9F186
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9755:CEPT1
gene id: 9755:CEPT1
uniprot id: A0A2Y9EGC2
uniprot id: A0A455B795
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

9755:LOC102993837
gene id: 9755:LOC102993837
uniprot id: A0A2Y9RZW4
names: Caution
names: Similarity
messages: Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:NSUN2
gene id: 9755:NSUN2
uniprot id: A0A2Y9SQA6
uniprot id: A0A455BL46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: extracellular exosome

9755:LOC102984370
gene id: 9755:LOC102984370
uniprot id: A0A2Y9EPP7
uniprot id: A0A455B7D0
uniprot id: A0A455B7D5
uniprot id: A0A455BA71
uniprot id: A0A455BLV2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

9755:PTAR1
gene id: 9755:PTAR1
uniprot id: A0A2Y9F9X7
uniprot id: A0A2Y9FA57
uniprot id: A0A455C120
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

9755:STARD13
gene id: 9755:STARD13
uniprot id: A0A2Y9FR93
names: Subcellular Location Annotation
messages: Cytoplasm

9755:LOC102988144
gene id: 9755:LOC102988144
uniprot id: A0A2Y9T8J8
names: Similarity
messages: Belongs to the FAM229 family.

9755:ANKS1B
gene id: 9755:ANKS1B
uniprot id: A0A2Y9SWG0
uniprot id: A0A2Y9SWG6
uniprot id: A0A2Y9SXT1
uniprot id: A0A2Y9SXT8
uniprot id: A0A2Y9T0D8
uniprot id: A0A2Y9T2B6
uniprot id: A0A2Y9T2C2
uniprot id: A0A2Y9T2C8
uniprot id: A0A2Y9T4H4
uniprot id: A0A2Y9T4H9
uniprot id: A0A455BBZ8
uniprot id: A0A455BC45
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

9755:PPM1F
gene id: 9755:PPM1F
uniprot id: A0A2Y9FUB5
uniprot id: A0A455AK90
names: Similarity
messages: Belongs to the PP2C family.

9755:TRPM3
gene id: 9755:TRPM3
uniprot id: A0A2Y9SVK1
uniprot id: A0A2Y9SVK6
uniprot id: A0A2Y9SWV2
uniprot id: A0A2Y9SWV7
uniprot id: A0A2Y9SZB4
uniprot id: A0A2Y9SZC1
uniprot id: A0A2Y9T1D4
uniprot id: A0A2Y9T1D9
uniprot id: A0A2Y9T3I9
uniprot id: A0A2Y9T3J4
uniprot id: A0A455BL24
uniprot id: A0A455BLC2
uniprot id: A0A455BLQ8
names: Subcellular Location Annotation
messages: Membrane

9755:OIP5
gene id: 9755:OIP5
uniprot id: A0A2Y9EZY2
uniprot id: A0A455BQL7
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
messages: centromere

9755:FAM163B
gene id: 9755:FAM163B
uniprot id: A0A2Y9EXV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

9755:GSS
gene id: 9755:GSS
uniprot id: A0A455C1S5
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic GSH synthase family.
messages: Binds 1 Mg(2+) ion per subunit.

9755:NMD3
gene id: 9755:NMD3
uniprot id: A0A2Y9F2P9
uniprot id: A0A455BFD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
messages: Belongs to the NMD3 family.
messages: Cytoplasm
messages: Nucleus

9755:PRPSAP2
gene id: 9755:PRPSAP2
uniprot id: A0A2Y9T461
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

9755:TRIM9
gene id: 9755:TRIM9
uniprot id: A0A2Y9F4F0
uniprot id: A0A455BQ92
names: Subcellular Location Annotation
messages: cytoskeleton

9755:ABCD1
gene id: 9755:ABCD1
uniprot id: A0A2Y9S5J5
uniprot id: A0A455ANY3
uniprot id: A0A455B2I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.
messages: Membrane
messages: Peroxisome membrane

9755:CMC4
gene id: 9755:CMC4
uniprot id: A0A2Y9S1T8
uniprot id: A0A455APH2
names: Similarity
messages: Belongs to the CMC4 family.

9755:RIOK3
gene id: 9755:RIOK3
uniprot id: A0A2Y9FNA2
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.
messages: Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses.

9755:DPCD
gene id: 9755:DPCD
uniprot id: A0A2Y9F2H6
names: Similarity
messages: Belongs to the DPCD family.

9755:PCNA
gene id: 9755:PCNA
uniprot id: A0A2Y9F433
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PCNA family.
messages: Nucleus
messages: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

9755:POLR1E
gene id: 9755:POLR1E
uniprot id: A0A2Y9EUD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.
messages: nucleolus

9755:CCDC43
gene id: 9755:CCDC43
uniprot id: A0A2Y9FKH2
names: Similarity
messages: Belongs to the CCDC43 family.

9755:CPS1
gene id: 9755:CPS1
uniprot id: A0A2Y9SP16
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:LOC102990546
gene id: 9755:LOC102990546
uniprot id: A0A2Y9SEW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:ZNF263
gene id: 9755:ZNF263
uniprot id: A0A2Y9FF52
uniprot id: A0A2Y9FH98
uniprot id: A0A455C1M0
names: Subcellular Location Annotation
messages: Nucleus

9755:ZSCAN29
gene id: 9755:ZSCAN29
uniprot id: A0A2Y9FIS1
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

9755:IL25
gene id: 9755:IL25
uniprot id: A0A455BR58
names: Similarity
messages: Belongs to the IL-17 family.

9755:CEMIP2
gene id: 9755:CEMIP2
uniprot id: A0A2Y9SWS0
uniprot id: A0A2Y9T3G1
names: Similarity
messages: Belongs to the CEMIP family.

9755:LOC102983402
gene id: 9755:LOC102983402
uniprot id: A0A2Y9SKX4
uniprot id: A0A2Y9SKX8
uniprot id: A0A2Y9SL11
uniprot id: A0A2Y9SLM5
uniprot id: A0A2Y9SLP7
uniprot id: A0A2Y9SPB3
uniprot id: A0A2Y9SPC4
uniprot id: A0A2Y9SPD1
uniprot id: A0A2Y9SPD6
uniprot id: A0A2Y9SS46
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

9755:SLC30A3
gene id: 9755:SLC30A3
uniprot id: A0A2Y9S8G9
uniprot id: A0A455BTY0
uniprot id: A0A455BUL4
uniprot id: A0A455C8K1
uniprot id: A0A455C8K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

9755:ARGLU1
gene id: 9755:ARGLU1
uniprot id: A0A2Y9EQ45
names: Similarity
messages: Belongs to the UPF0430 family.

9755:NIPBL
gene id: 9755:NIPBL
uniprot id: A0A455BI50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC2/Nipped-B family.
messages: Nucleus

9755:BASP1
gene id: 9755:BASP1
uniprot id: A0A2Y9SIX0
names: Similarity
messages: Belongs to the BASP1 family.

9755:INSIG1
gene id: 9755:INSIG1
uniprot id: A0A2Y9T9E0
uniprot id: A0A455B8N9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates feedback control of cholesterol synthesis.
messages: Membrane

9755:PNRC1
gene id: 9755:PNRC1
uniprot id: A0A2Y9EJD5
names: Subcellular Location Annotation
messages: Nucleus

9755:SQSTM1
gene id: 9755:SQSTM1
uniprot id: A0A2Y9FB24
names: Subcellular Location Annotation
messages: Lysosome
messages: autophagosome

9755:CD34
gene id: 9755:CD34
uniprot id: A0A2Y9F4N0
uniprot id: A0A2Y9F5H0
names: Subcellular Location Annotation
messages: Membrane

9755:LOC102979005
gene id: 9755:LOC102979005
uniprot id: A0A455AEE9
names: Subcellular Location Annotation
messages: Nucleus

9755:TYSND1
gene id: 9755:TYSND1
uniprot id: A0A2Y9EJ78
uniprot id: A0A2Y9EKN8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1B family.
messages: Peroxisomal protease that mediates both the removal of the leader peptide from proteins containing a PTS2 target sequence and processes several PTS1-containing proteins. Catalyzes the processing of PTS1-proteins involved in the peroxisomal beta-oxidation of fatty acids.
messages: Peroxisome
messages: The full-lengh TYSND1 is the active the proteolytic processing of PTS1- and PTS2-proteins and in self-cleavage, and intermolecular self-cleavage of TYSND1 down-regulates its protease activity.

9755:UTP23
gene id: 9755:UTP23
uniprot id: A0A2Y9T2K9
names: Subcellular Location Annotation
messages: nucleolus

9755:CXCR1
gene id: 9755:CXCR1
uniprot id: A0A455BTK9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9755:CDKL1
gene id: 9755:CDKL1
uniprot id: A0A455BRP7
uniprot id: A0A455BV19
names: Similarity
messages: Belongs to the protein kinase superfamily.

9755:PDZK1IP1
gene id: 9755:PDZK1IP1
uniprot id: A0A2Y9SE71
names: Subcellular Location Annotation
messages: Membrane

9755:GNS
gene id: 9755:GNS
uniprot id: A0A2Y9F808
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Lysosome
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

9755:WNT2
gene id: 9755:WNT2
uniprot id: A0A2Y9F3Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9755:TLR6
gene id: 9755:TLR6
uniprot id: A0A2Y9EGM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

9755:TMEM9B
gene id: 9755:TMEM9B
uniprot id: A0A2Y9ELW6
uniprot id: A0A2Y9EN99
uniprot id: A0A455C6N9
names: Similarity
messages: Belongs to the TMEM9 family.

9755:HDDC2
gene id: 9755:HDDC2
uniprot id: A0A2Y9F3X8
uniprot id: A0A2Y9SPH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HDDC2 family.
messages: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
messages: Homodimer.

9755:PRKAR2A
gene id: 9755:PRKAR2A
uniprot id: A0A2Y9SQ82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

9755:BANF2
gene id: 9755:BANF2
uniprot id: A0A2Y9EWX1
names: Subcellular Location Annotation
messages: Nucleus

9755:MAPK14
gene id: 9755:MAPK14
uniprot id: A0A2Y9SFQ4
uniprot id: A0A2Y9SMC1
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

9755:F2R
gene id: 9755:F2R
uniprot id: A0A2Y9EPC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9755:SMC5
gene id: 9755:SMC5
uniprot id: A0A2Y9SWD7
uniprot id: A0A2Y9SYU4
uniprot id: A0A2Y9T327
uniprot id: A0A455BLR3
uniprot id: A0A455BPB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC5 subfamily.
messages: Chromosome
messages: Nucleus

9755:LOC102986675
gene id: 9755:LOC102986675
uniprot id: A0A2Y9F9I0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space
messages: Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

9755:SPG7
gene id: 9755:SPG7
uniprot id: A0A2Y9SYI8
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

9755:TLCD4
gene id: 9755:TLCD4
uniprot id: A0A2Y9SIU6
names: Subcellular Location Annotation
messages: Membrane

9755:TACR1
gene id: 9755:TACR1
uniprot id: A0A2Y9TK96
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with ARRB1.
messages: Membrane

9755:HS2ST1
gene id: 9755:HS2ST1
uniprot id: A0A2Y9EQX9
uniprot id: A0A2Y9ESG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Golgi apparatus membrane
messages: Membrane

9755:NDUFB5
gene id: 9755:NDUFB5
uniprot id: A0A2Y9ENP4
uniprot id: A0A2Y9ENT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB5 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9755:LOC112062151
gene id: 9755:LOC112062151
uniprot id: A0A2Y9S271
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

9755:GDAP2
gene id: 9755:GDAP2
uniprot id: A0A2Y9SAE1
uniprot id: A0A2Y9SIP2
uniprot id: A0A455B9W9
names: Similarity
messages: Belongs to the GDAP2 family.

9755:SNX17
gene id: 9755:SNX17
uniprot id: A0A2Y9ETK1
uniprot id: A0A2Y9EUW5
uniprot id: A0A455BUS3
uniprot id: A0A455BXJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane
messages: Early endosome
messages: Endosome
messages: Membrane

9755:KIF24
gene id: 9755:KIF24
uniprot id: A0A2Y9EE78
uniprot id: A0A2Y9EFX2
uniprot id: A0A455BPU7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9755:TRAPPC13
gene id: 9755:TRAPPC13
uniprot id: A0A2Y9EIB2
uniprot id: A0A2Y9EJ20
uniprot id: A0A2Y9EKD7
uniprot id: A0A2Y9EKJ2
names: Similarity
names: Subunit
messages: Belongs to the TRAPPC13 family.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.

9755:ALG9
gene id: 9755:ALG9
uniprot id: A0A2Y9FRT6
uniprot id: A0A2Y9T7X3
uniprot id: A0A2Y9T9X1
uniprot id: A0A2Y9TDV9
uniprot id: A0A2Y9TFR7
uniprot id: A0A2Y9TFS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:CASKIN2
gene id: 9755:CASKIN2
uniprot id: A0A2Y9T5I3
uniprot id: A0A455CA69
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

9755:DRAM1
gene id: 9755:DRAM1
uniprot id: A0A2Y9T0V5
names: Subcellular Location Annotation
messages: Membrane

9755:SEC11A
gene id: 9755:SEC11A
uniprot id: A0A2Y9EPR1
uniprot id: A0A455BQK0
uniprot id: A0A455BT62
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Component of the signal peptidase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:GRIN3A
gene id: 9755:GRIN3A
uniprot id: A0A2Y9SU75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

9755:DUSP9
gene id: 9755:DUSP9
uniprot id: A0A2Y9S9U2
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

9755:MFAP1
gene id: 9755:MFAP1
uniprot id: A0A2Y9F3A9
names: Function
names: Similarity
messages: Belongs to the MFAP1 family.
messages: Involved in pre-mRNA splicing as a component of the spliceosome.

9755:SOX3
gene id: 9755:SOX3
uniprot id: A0A2Y9SZ57
names: Subcellular Location Annotation
messages: Nucleus

9755:LOC114487616
gene id: 9755:LOC114487616
uniprot id: A0A455C2Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

9755:IGF2BP1
gene id: 9755:IGF2BP1
uniprot id: A0A2Y9TA81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM IMP/VICKZ family.
messages: Nucleus
messages: P-body
messages: Stress granule
messages: filopodium
messages: growth cone
messages: lamellipodium
messages: perinuclear region

9755:C1D
gene id: 9755:C1D
uniprot id: A0A2Y9ENM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the C1D family.
messages: Cytoplasm
messages: Monomer and homodimer.
messages: Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA.
messages: nucleolus

9755:CACNG4
gene id: 9755:CACNG4
uniprot id: A0A2Y9TBQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization.

9755:DNAL4
gene id: 9755:DNAL4
uniprot id: A0A2Y9EY99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

9755:DNAJC2
gene id: 9755:DNAJC2
uniprot id: A0A2Y9FS09
uniprot id: A0A2Y9FTX6
names: Function
names: Subcellular Location Annotation
messages: Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain. When nuclear, mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at 'Lys-119' (H2AK119ub), and promotes the displacement of the polycomb PRC1 complex from chromatin, thereby facilitating transcription activation.
messages: cytosol

9755:LOC102973809
gene id: 9755:LOC102973809
uniprot id: A0A2Y9FJE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Secreted

9755:CNOT6
gene id: 9755:CNOT6
uniprot id: A0A2Y9FGA2
uniprot id: A0A2Y9FGJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

9755:HTR4
gene id: 9755:HTR4
uniprot id: A0A2Y9T0B4
uniprot id: A0A455BK75
uniprot id: A0A455BMQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Endosome
messages: Membrane
messages: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.

9755:LGI2
gene id: 9755:LGI2
uniprot id: A0A2Y9S9B3
names: Subcellular Location Annotation
messages: Secreted

9755:IGF2BP2
gene id: 9755:IGF2BP2
uniprot id: A0A2Y9SRF6
uniprot id: A0A2Y9SW87
uniprot id: A0A455BG04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM IMP/VICKZ family.
messages: P-body
messages: Stress granule

9755:PDE6C
gene id: 9755:PDE6C
uniprot id: A0A2Y9ER64
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9755:RNF168
gene id: 9755:RNF168
uniprot id: A0A2Y9SR86
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: According to a well-established model, RNF168 cannot initiate H2A 'Lys-63'-linked ubiquitination and is recruited following RNF8-dependent histone ubiquitination to amplify H2A 'Lys-63'-linked ubiquitination. However, other data suggest that RNF168 is the priming ubiquitin ligase by mediating monoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histone H2A (H2AK13Ub and H2AK15Ub respectively). These data suggest that RNF168 might be recruited to DSBs sites in a RNF8-dependent manner by binding to non-histone proteins ubiquitinated via 'Lys-63'-linked and initiates monoubiquitination of H2A, which is then amplified by RNF8. Additional evidences are however required to confirm these data.
messages: Belongs to the RNF168 family.
messages: E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recruited at DNA interstrand cross-links (ICLs) sites and promotes accumulation of 'Lys-63'-linked ubiquitination of histones H2A and H2AX, leading to recruitment of FAAP20 and Fanconi anemia (FA) complex, followed by interstrand cross-link repair. H2A ubiquitination also mediates the ATM-dependent transcriptional silencing at regions flanking DSBs in cis, a mechanism to avoid collision between transcription and repair intermediates. Also involved in class switch recombination in immune system, via its role in regulation of DSBs repair. Following DNA damage, promotes the ubiquitination and degradation of JMJD2A/KDM4A in collaboration with RNF8, leading to unmask H4K20me2 mark and promote the recruitment of TP53BP1 at DNA damage sites. Not able to initiate 'Lys-63'-linked ubiquitination in vitro; possibly due to partial occlusion of the UBE2N/UBC13-binding region. Catalyzes monoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histone H2A (H2AK13Ub and H2AK15Ub, respectively).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with UBE2N/UBC13.
messages: Nucleus
messages: Sumoylated with SUMO1 by PIAS4 in response to double-strand breaks (DSBs).
messages: The MIU motif (motif interacting with ubiquitin) mediates the interaction with both 'Lys-48'- and 'Lys-63'-linked ubiquitin chains. The UMI motif mediates interaction with ubiquitin with a preference for 'Lys-63'-linked ubiquitin. The specificity for different types of ubiquitin is mediated by juxtaposition of ubiquitin-binding motifs (MIU and UMI motifs) with LR motifs (LRMs).
messages: Ubiquitinated.

9755:CACNA1E
gene id: 9755:CACNA1E
uniprot id: A0A2Y9ENQ1
uniprot id: A0A2Y9EPR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents.

9755:LOC102987877
gene id: 9755:LOC102987877
uniprot id: A0A2Y9FPZ5
uniprot id: A0A2Y9FQ29
uniprot id: A0A2Y9FQA8
uniprot id: A0A2Y9FRX8
uniprot id: A0A2Y9FSS2
uniprot id: A0A2Y9SHR3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

9755:INO80C
gene id: 9755:INO80C
uniprot id: A0A2Y9FAV5
names: Subcellular Location Annotation
messages: Nucleus

9755:ENTREP2
gene id: 9755:ENTREP2
uniprot id: A0A2Y9T751
names: Similarity
messages: Belongs to the ENTREP family.

9755:FAM171A1
gene id: 9755:FAM171A1
uniprot id: A0A2Y9S0L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

9755:TAS2R4
gene id: 9755:TAS2R4
uniprot id: A0A2Y9T9M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

9755:LOC102982470
gene id: 9755:LOC102982470
uniprot id: A0A455BZU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

9755:CLK3
gene id: 9755:CLK3
uniprot id: A0A2Y9F2C8
names: Similarity
messages: Belongs to the protein kinase superfamily.

9755:CITED1
gene id: 9755:CITED1
uniprot id: A0A2Y9T7L9
uniprot id: A0A455APF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

9755:PFN2
gene id: 9755:PFN2
uniprot id: A0A2Y9TD38
uniprot id: A0A2Y9TFE0
uniprot id: A0A2Y9TH36
uniprot id: A0A455B6W6
names: Similarity
messages: Belongs to the profilin family.

9755:PKM
gene id: 9755:PKM
uniprot id: A0A2Y9FAF8
uniprot id: A0A2Y9T8N5
uniprot id: A0A455BPC7
uniprot id: A0A455BPE8
names: Similarity
messages: Belongs to the pyruvate kinase family.

9755:NKAIN2
gene id: 9755:NKAIN2
uniprot id: A0A455BRR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

9755:LOC102975023
gene id: 9755:LOC102975023
uniprot id: A0A2Y9EJQ9
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

9755:CHRM2
gene id: 9755:CHRM2
uniprot id: A0A2Y9EY80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

9755:CDC42
gene id: 9755:CDC42
uniprot id: A0A2Y9SZ98
uniprot id: A0A455B4Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

9755:UPK1A
gene id: 9755:UPK1A
uniprot id: A0A2Y9TDA9
uniprot id: A0A455ACJ7
uniprot id: A0A455AQ22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9755:GINS2
gene id: 9755:GINS2
uniprot id: A0A2Y9SVM3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS2/PSF2 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus

9755:NTS
gene id: 9755:NTS
uniprot id: A0A2Y9EVV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurotensin family.
messages: Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.
messages: Secreted
messages: Vesicle
messages: secretory vesicle

9755:SLC5A3
gene id: 9755:SLC5A3
uniprot id: A0A2Y9SC12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

9755:SGIP1
gene id: 9755:SGIP1
uniprot id: A0A455B810
uniprot id: A0A455B813
uniprot id: A0A455B8H0
uniprot id: A0A455B8H5
uniprot id: A0A455B8U3
uniprot id: A0A455BAV5
uniprot id: A0A455BMH6
names: Function
names: Subcellular Location Annotation
messages: May function in clathrin-mediated endocytosis. Has both a membrane binding/tubulating activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a preference for membranes enriched in phosphatidylserine and phosphoinositides and is required for the endocytosis of the transferrin receptor. May also bind tubulin. May play a role in the regulation of energy homeostasis.
messages: clathrin-coated pit

9755:FERMT3
gene id: 9755:FERMT3
uniprot id: A0A2Y9EHT8
names: Similarity
messages: Belongs to the kindlin family.

9755:LOC102993677
gene id: 9755:LOC102993677
uniprot id: A0A2Y9T9B8
names: Similarity
messages: Belongs to the Bcl-2 family.

9755:LOC102986969
gene id: 9755:LOC102986969
uniprot id: A0A2Y9SU66
uniprot id: A0A455C1E4
names: Subcellular Location Annotation
messages: Nucleus

9755:DNAH12
gene id: 9755:DNAH12
uniprot id: A0A2Y9SQ72
names: Similarity
messages: Belongs to the dynein heavy chain family.

9755:CCR1
gene id: 9755:CCR1
uniprot id: A0A2Y9FLE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

9755:CPQ
gene id: 9755:CPQ
uniprot id: A0A2Y9S750
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Carboxypeptidase that may play an important role in the hydrolysis of circulating peptides. Catalyzes the hydrolysis of dipeptides with unsubstituted terminals into amino acids. May play a role in the liberation of thyroxine hormone from its thyroglobulin (Tg) precursor.
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer. The monomeric form is inactive while the homodimer is active.
messages: Lysosome

9755:TOLLIP
gene id: 9755:TOLLIP
uniprot id: A0A2Y9S7P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tollip family.
messages: Cytoplasm

9755:EIF5B
gene id: 9755:EIF5B
uniprot id: A0A2Y9FAK7
uniprot id: A0A2Y9FAL6
uniprot id: A0A2Y9FAL7
uniprot id: A0A2Y9FAY5
uniprot id: A0A2Y9FAZ2
uniprot id: A0A2Y9T3K3
uniprot id: A0A455BVW8
uniprot id: A0A455BYQ3
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.

9755:AASDHPPT
gene id: 9755:AASDHPPT
uniprot id: A0A2Y9FA74
names: Similarity
messages: Belongs to the P-Pant transferase superfamily. AcpS family.

9755:ARCN1
gene id: 9755:ARCN1
uniprot id: A0A2Y9FKT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

9755:C17H19orf12
gene id: 9755:C17H19orf12
uniprot id: A0A2Y9TIB7
uniprot id: A0A455ACH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the C19orf12 family.
messages: Mitochondrion membrane

9755:CRELD2
gene id: 9755:CRELD2
uniprot id: A0A2Y9FP19
uniprot id: A0A455BFD1
names: Caution
names: Similarity
messages: Belongs to the CRELD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:CRB1
gene id: 9755:CRB1
uniprot id: A0A2Y9T9L6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:AFP
gene id: 9755:AFP
uniprot id: A0A2Y9FP24
names: Subcellular Location Annotation
messages: Secreted

9755:CCN1
gene id: 9755:CCN1
uniprot id: A0A2Y9FEA7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9755:TOP2B
gene id: 9755:TOP2B
uniprot id: A0A2Y9F3M6
uniprot id: A0A2Y9RX81
uniprot id: A0A455BAY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Homodimer.
messages: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand.
messages: nucleolus
messages: nucleoplasm

9755:LOC102990859
gene id: 9755:LOC102990859
uniprot id: A0A2Y9EDD1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9755:ING3
gene id: 9755:ING3
uniprot id: A0A2Y9F3Y9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

9755:PFN4
gene id: 9755:PFN4
uniprot id: A0A2Y9F474
uniprot id: A0A455BVK2
names: Similarity
messages: Belongs to the profilin family.

9755:PFKFB3
gene id: 9755:PFKFB3
uniprot id: A0A2Y9FCP8
uniprot id: A0A455BTD0
uniprot id: A0A455BU16
uniprot id: A0A455BWR7
uniprot id: A0A455C8A7
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

9755:PEAR1
gene id: 9755:PEAR1
uniprot id: A0A2Y9EYF7
uniprot id: A0A455B6J9
uniprot id: A0A455B6Z1
uniprot id: A0A455B9B7
uniprot id: A0A455BKY9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:CDC42EP4
gene id: 9755:CDC42EP4
uniprot id: A0A2Y9T465
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

9755:DOP1B
gene id: 9755:DOP1B
uniprot id: A0A2Y9SCD4
names: Similarity
messages: Belongs to the dopey family.

9755:CRYBA2
gene id: 9755:CRYBA2
uniprot id: A0A2Y9F9U1
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

9755:MED11
gene id: 9755:MED11
uniprot id: A0A2Y9EU95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 11 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

9755:TNNT3
gene id: 9755:TNNT3
uniprot id: A0A2Y9FNB7
uniprot id: A0A455ADW6
uniprot id: A0A455ADX1
uniprot id: A0A455AEB5
uniprot id: A0A455AEB9
uniprot id: A0A455AFJ3
uniprot id: A0A455AGB3
uniprot id: A0A455AGB7
uniprot id: A0A455AGC1
uniprot id: A0A455ARN8
uniprot id: A0A455ARP4
uniprot id: A0A455ARP8
names: Caution
names: Function
names: Similarity
messages: Belongs to the troponin T family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

9755:NDUFV3
gene id: 9755:NDUFV3
uniprot id: A0A2Y9EY21
uniprot id: A0A2Y9EZ38
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. May be the terminally assembled subunit of Complex I.
messages: Belongs to the complex I NDUFV3 subunit family.
messages: Complex I is composed of 45 different subunits. This is a component of the flavoprotein-sulfur (FP) fragment of the enzyme.

9755:WLS
gene id: 9755:WLS
uniprot id: A0A2Y9FAY3
uniprot id: A0A2Y9FAY6
uniprot id: A0A455B8F7
uniprot id: A0A455BAT7
uniprot id: A0A455BMF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the wntless family.
messages: Golgi apparatus membrane
messages: Membrane

9755:LOC102984570
gene id: 9755:LOC102984570
uniprot id: A0A2Y9FQL5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9755:SLC66A2
gene id: 9755:SLC66A2
uniprot id: A0A2Y9F053
uniprot id: A0A2Y9F1P7
uniprot id: A0A455AHZ6
names: Subcellular Location Annotation
messages: Membrane

9755:LOC102979298
gene id: 9755:LOC102979298
uniprot id: A0A2Y9FPQ1
uniprot id: A0A2Y9S9F1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Cytoplasm
messages: Homodimer.
messages: Pyrophosphatase that hydrolyzes the non-canonical purine (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.

9755:LOC102989563
gene id: 9755:LOC102989563
uniprot id: A0A2Y9SNC2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:FTSJ3
gene id: 9755:FTSJ3
uniprot id: A0A2Y9EMC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
messages: Interacts with NIP7.
messages: Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation.
messages: nucleolus

9755:HHIP
gene id: 9755:HHIP
uniprot id: A0A2Y9F773
uniprot id: A0A2Y9F7K9
uniprot id: A0A2Y9F811
uniprot id: A0A2Y9F958
names: Caution
names: Similarity
messages: Belongs to the HHIP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:TMEM167A
gene id: 9755:TMEM167A
uniprot id: A0A2Y9EIM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KISH family.
messages: Golgi apparatus membrane
messages: Involved in the early part of the secretory pathway.
messages: Membrane

9755:MYORG
gene id: 9755:MYORG
uniprot id: A0A455BLL4
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

9755:GABPA
gene id: 9755:GABPA
uniprot id: A0A2Y9F9G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9755:LOC102978605
gene id: 9755:LOC102978605
uniprot id: A0A2Y9RZL0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:PPIL2
gene id: 9755:PPIL2
uniprot id: A0A2Y9FU59
uniprot id: A0A455AHJ9
uniprot id: A0A455AJI3
uniprot id: A0A455AVX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.
messages: Nucleus

9755:HNF1A
gene id: 9755:HNF1A
uniprot id: A0A2Y9EP35
uniprot id: A0A2Y9SHL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HNF1 homeobox family.
messages: Nucleus

9755:LOC102984856
gene id: 9755:LOC102984856
uniprot id: A0A455AI69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: cytoskeleton

9755:CELF3
gene id: 9755:CELF3
uniprot id: A0A2Y9F8B8
uniprot id: A0A2Y9F8M6
uniprot id: A0A2Y9F8M8
uniprot id: A0A2Y9F924
uniprot id: A0A2Y9F929
uniprot id: A0A2Y9RZV1
uniprot id: A0A2Y9RZV6
uniprot id: A0A2Y9RZW2
uniprot id: A0A2Y9RZW7
uniprot id: A0A2Y9RZX7
uniprot id: A0A2Y9RZY1
uniprot id: A0A2Y9RZY3
uniprot id: A0A2Y9RZY8
uniprot id: A0A2Y9RZZ6
uniprot id: A0A2Y9RZZ9
uniprot id: A0A2Y9S005
uniprot id: A0A2Y9S010
uniprot id: A0A2Y9S014
uniprot id: A0A2Y9S018
uniprot id: A0A2Y9S023
uniprot id: A0A2Y9S028
uniprot id: A0A2Y9S3C5
uniprot id: A0A2Y9S3E2
uniprot id: A0A2Y9S3H1
uniprot id: A0A2Y9S3H7
uniprot id: A0A2Y9S3I2
uniprot id: A0A2Y9S3J3
uniprot id: A0A2Y9S6X9
uniprot id: A0A2Y9S6Y4
uniprot id: A0A2Y9S6Y7
uniprot id: A0A2Y9S6Z2
uniprot id: A0A2Y9S705
uniprot id: A0A2Y9S710
uniprot id: A0A2Y9S715
uniprot id: A0A2Y9S7X1
uniprot id: A0A2Y9S7X5
uniprot id: A0A2Y9S7X8
uniprot id: A0A2Y9S7Y7
uniprot id: A0A2Y9S7Z5
uniprot id: A0A2Y9S7Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Nucleus

9755:NKX2-5
gene id: 9755:NKX2-5
uniprot id: A0A2Y9F350
names: Subcellular Location Annotation
messages: Nucleus

9755:LOC102979564
gene id: 9755:LOC102979564
uniprot id: A0A2Y9T7I7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens.
messages: Belongs to the IL-1 family.
messages: Secreted

9755:NKX2-8
gene id: 9755:NKX2-8
uniprot id: A0A2Y9EPF1
names: Subcellular Location Annotation
messages: Nucleus

9755:PRTFDC1
gene id: 9755:PRTFDC1
uniprot id: A0A2Y9T3E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

9755:NRG2
gene id: 9755:NRG2
uniprot id: A0A2Y9SK85
uniprot id: A0A2Y9SKX0
uniprot id: A0A2Y9SRI9
uniprot id: A0A2Y9SRJ3
uniprot id: A0A2Y9STH7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9755:TNFRSF9
gene id: 9755:TNFRSF9
uniprot id: A0A2Y9SSQ3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:NCAN
gene id: 9755:NCAN
uniprot id: A0A2Y9TKU6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aggrecan/versican proteoglycan family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9755:LOC102975133
gene id: 9755:LOC102975133
uniprot id: A0A2Y9FLV1
uniprot id: A0A2Y9FMV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYBC1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:AMZ2
gene id: 9755:AMZ2
uniprot id: A0A455C125
uniprot id: A0A455C588
names: Function
names: Similarity
messages: Belongs to the peptidase M54 family.
messages: Probable zinc metalloprotease.

9755:PTPN11
gene id: 9755:PTPN11
uniprot id: A0A2Y9SDV4
uniprot id: A0A2Y9SKK4
uniprot id: A0A455AXD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm

9755:BAK1
gene id: 9755:BAK1
uniprot id: A0A2Y9FR10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane

9755:ART4
gene id: 9755:ART4
uniprot id: A0A2Y9ET92
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

9755:DUOXA2
gene id: 9755:DUOXA2
uniprot id: A0A2Y9FF81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DUOXA family.
messages: Membrane

9755:CACHD1
gene id: 9755:CACHD1
uniprot id: A0A2Y9SGX2
uniprot id: A0A455B8I7
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

9755:TMEM65
gene id: 9755:TMEM65
uniprot id: A0A2Y9T2J6
names: Subcellular Location Annotation
messages: Membrane

9755:STOML1
gene id: 9755:STOML1
uniprot id: A0A2Y9EXX2
uniprot id: A0A2Y9T0K0
uniprot id: A0A455BRZ7
uniprot id: A0A455BSP7
uniprot id: A0A455C753
names: Similarity
messages: Belongs to the band 7/mec-2 family.

9755:FES
gene id: 9755:FES
uniprot id: A0A2Y9ESW1
uniprot id: A0A2Y9EUU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.
messages: Cell membrane
messages: Membrane
messages: cytoskeleton

9755:TNFRSF11A
gene id: 9755:TNFRSF11A
uniprot id: A0A455AV43
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:PAQR7
gene id: 9755:PAQR7
uniprot id: A0A2Y9FLA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

9755:STMN2
gene id: 9755:STMN2
uniprot id: A0A2Y9F4Y8
names: Similarity
messages: Belongs to the stathmin family.

9755:UBLCP1
gene id: 9755:UBLCP1
uniprot id: A0A2Y9F750
names: Subcellular Location Annotation
messages: Nucleus

9755:VPS4A
gene id: 9755:VPS4A
uniprot id: A0A2Y9SRJ9
uniprot id: A0A2Y9STS4
uniprot id: A0A455ADS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

9755:MRPL53
gene id: 9755:MRPL53
uniprot id: A0A2Y9ES60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL53 family.
messages: Mitochondrion

9755:AMFR
gene id: 9755:AMFR
uniprot id: A0A2Y9SPJ0
names: Subcellular Location Annotation
messages: Membrane

9755:POC5
gene id: 9755:POC5
uniprot id: A0A2Y9F4D4
uniprot id: A0A2Y9F4H5
uniprot id: A0A2Y9F582
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POC5 family.
messages: Essential for the assembly of the distal half of centrioles, required for centriole elongation.
messages: centriole

9755:TERF1
gene id: 9755:TERF1
uniprot id: A0A2Y9SX31
uniprot id: A0A2Y9T3T5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.
messages: Homodimer.
messages: Nucleus
messages: telomere

9755:CLRN1
gene id: 9755:CLRN1
uniprot id: A0A2Y9F4W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

9755:PES1
gene id: 9755:PES1
uniprot id: A0A2Y9FQP8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pescadillo family.
messages: Chromosome
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome. Interacts with IRS1 and UBTF. May interact with MAP1B.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: Sumoylated.
messages: nucleolus
messages: nucleoplasm

9755:CA2
gene id: 9755:CA2
uniprot id: A0A2Y9F931
uniprot id: A0A455C8P2
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

9755:NAP1L5
gene id: 9755:NAP1L5
uniprot id: A0A2Y9FJ29
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9755:LGR4
gene id: 9755:LGR4
uniprot id: A0A2Y9F8T3
names: Subcellular Location Annotation
messages: Membrane

9755:LOC102980685
gene id: 9755:LOC102980685
uniprot id: A0A2Y9FB61
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9755:PDIA6
gene id: 9755:PDIA6
uniprot id: A0A2Y9SDK1
uniprot id: A0A2Y9SF00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen
messages: Melanosome

9755:CENPI
gene id: 9755:CENPI
uniprot id: A0A2Y9EY04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-I/CTF3 family.
messages: Nucleus
messages: centromere

9755:NRCAM
gene id: 9755:NRCAM
uniprot id: A0A2Y9S047
names: Similarity
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.

9755:LOC102996375
gene id: 9755:LOC102996375
uniprot id: A0A2Y9EZT0
uniprot id: A0A2Y9F0X3
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.

9755:RPA2
gene id: 9755:RPA2
uniprot id: A0A2Y9FDK2
uniprot id: A0A2Y9FDL2
uniprot id: A0A2Y9FFI2
names: Similarity
messages: Belongs to the replication factor A protein 2 family.

9755:MLLT11
gene id: 9755:MLLT11
uniprot id: A0A2Y9S824
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLLT11 family.
messages: Nucleus
messages: centrosome

9755:VEZT
gene id: 9755:VEZT
uniprot id: A0A2Y9SXV0
uniprot id: A0A2Y9T4J4
uniprot id: A0A455BBA8
uniprot id: A0A455BC24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vezatin family.
messages: Cell membrane
messages: Membrane
messages: Nucleus
messages: adherens junction

9755:DNAJB14
gene id: 9755:DNAJB14
uniprot id: A0A2Y9FD31
uniprot id: A0A2Y9FD95
uniprot id: A0A2Y9FF66
uniprot id: A0A455BFC7
uniprot id: A0A455BUH3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:DNAH1
gene id: 9755:DNAH1
uniprot id: A0A455ASD1
names: Similarity
messages: Belongs to the dynein heavy chain family.

9755:MBP
gene id: 9755:MBP
uniprot id: A0A2Y9FLP1
uniprot id: A0A2Y9THK7
uniprot id: A0A455AJ70
uniprot id: A0A455AKQ1
uniprot id: A0A455AKR5
uniprot id: A0A455AKR9
uniprot id: A0A455AX83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin basic protein family.
messages: Myelin membrane

9755:LCAT
gene id: 9755:LCAT
uniprot id: A0A455ADR2
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

9755:STXBP5L
gene id: 9755:STXBP5L
uniprot id: A0A2Y9SCU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat L(2)GL family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

9755:PHF20
gene id: 9755:PHF20
uniprot id: A0A2Y9T3I5
uniprot id: A0A455BYE0
uniprot id: A0A455BZA6
names: Subcellular Location Annotation
messages: Nucleus

9755:SUDS3
gene id: 9755:SUDS3
uniprot id: A0A2Y9FGE0
uniprot id: A0A2Y9SDH2
uniprot id: A0A455AJ90
uniprot id: A0A455AJL7
uniprot id: A0A455AJM1
uniprot id: A0A455AL39
uniprot id: A0A455AL63
names: Subcellular Location Annotation
messages: Nucleus

9755:GAD2
gene id: 9755:GAD2
uniprot id: A0A2Y9T547
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

9755:SSR2
gene id: 9755:SSR2
uniprot id: A0A2Y9EX53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-beta family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

9755:TAF7L
gene id: 9755:TAF7L
uniprot id: A0A2Y9EXG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

9755:DERL2
gene id: 9755:DERL2
uniprot id: A0A2Y9EIU6
uniprot id: A0A2Y9EJJ2
uniprot id: A0A2Y9SY23
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:OGFR
gene id: 9755:OGFR
uniprot id: A0A2Y9EFI3
names: Similarity
messages: Belongs to the opioid growth factor receptor family.

9755:RNGTT
gene id: 9755:RNGTT
uniprot id: A0A2Y9S8J9
uniprot id: A0A455BN96
uniprot id: A0A455BNF6
uniprot id: A0A455BNZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate.
messages: In the C-terminal section; belongs to the eukaryotic GTase family.
messages: In the N-terminal section; belongs to the non-receptor class of the protein-tyrosine phosphatase family.
messages: Nucleus

9755:LOC102986298
gene id: 9755:LOC102986298
uniprot id: A0A2Y9T9Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H2 subunit B family.
messages: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Nucleus
messages: The RNase H2 complex is a heterotrimer composed of the catalytic subunit RNASEH2A and the non-catalytic subunits RNASEH2B and RNASEH2C.

9755:ANXA2
gene id: 9755:ANXA2
uniprot id: A0A2Y9FM81
uniprot id: A0A2Y9FMS1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9.
messages: Membrane
messages: basement membrane

9755:IDNK
gene id: 9755:IDNK
uniprot id: A0A2Y9TEF5
uniprot id: A0A2Y9TJB5
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

9755:DYNLT2
gene id: 9755:DYNLT2
uniprot id: A0A455BP82
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

9755:LOC102975660
gene id: 9755:LOC102975660
uniprot id: A0A2Y9EYM3
uniprot id: A0A2Y9F0P8
names: Similarity
messages: Belongs to the GroES chaperonin family.

9755:ABCA4
gene id: 9755:ABCA4
uniprot id: A0A2Y9FRB4
names: Subcellular Location Annotation
messages: Membrane

9755:CD109
gene id: 9755:CD109
uniprot id: A0A2Y9TII6
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.

9755:ADCK5
gene id: 9755:ADCK5
uniprot id: A0A2Y9SAD4
uniprot id: A0A2Y9SBU8
uniprot id: A0A455C3V8
uniprot id: A0A455C3W4
uniprot id: A0A455C3X0
uniprot id: A0A455C453
uniprot id: A0A455C458
uniprot id: A0A455C4Y4
uniprot id: A0A455C863
uniprot id: A0A455CBA9
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

9755:NPNT
gene id: 9755:NPNT
uniprot id: A0A455BGM3
uniprot id: A0A455BGU4
uniprot id: A0A455BJ89
names: Caution
names: Similarity
messages: Belongs to the nephronectin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:INIP
gene id: 9755:INIP
uniprot id: A0A2Y9SZI1
uniprot id: A0A455BNJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SOSS-C family.
messages: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs).
messages: Component of the SOSS complex.
messages: Nucleus

9755:CDK10
gene id: 9755:CDK10
uniprot id: A0A2Y9STW1
names: Similarity
messages: Belongs to the protein kinase superfamily.

9755:LOC102991401
gene id: 9755:LOC102991401
uniprot id: A0A2Y9RWN4
uniprot id: A0A2Y9S0F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

9755:LOC102974327
gene id: 9755:LOC102974327
uniprot id: A0A2Y9F4P7
names: Subcellular Location Annotation
messages: Membrane

9755:ADGRG2
gene id: 9755:ADGRG2
uniprot id: A0A2Y9EQ61
uniprot id: A0A2Y9EQP9
uniprot id: A0A2Y9ERN5
uniprot id: A0A2Y9RWW5
uniprot id: A0A2Y9RXK9
uniprot id: A0A2Y9S0P6
names: Subcellular Location Annotation
messages: Membrane

9755:BCHE
gene id: 9755:BCHE
uniprot id: A0A2Y9SP91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Secreted

9755:DRAM2
gene id: 9755:DRAM2
uniprot id: A0A2Y9EHA8
names: Subcellular Location Annotation
messages: Membrane

9755:DNTTIP2
gene id: 9755:DNTTIP2
uniprot id: A0A2Y9FPE5
names: Subcellular Location Annotation
messages: nucleolus

9755:GUCY1B1
gene id: 9755:GUCY1B1
uniprot id: A0A2Y9F3E4
uniprot id: A0A2Y9T2U5
uniprot id: A0A455BEF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

9755:PDLIM3
gene id: 9755:PDLIM3
uniprot id: A0A2Y9F789
uniprot id: A0A2Y9TAD8
names: Subcellular Location Annotation
messages: Z line

9755:LOC102996773
gene id: 9755:LOC102996773
uniprot id: A0A2Y9F913
names: Subcellular Location Annotation
messages: Cytoplasm

9755:KEF67 p08
gene id: 9755:KEF67_p08
uniprot id: Q9MET1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
messages: Mitochondrion inner membrane

9755:FOXF1
gene id: 9755:FOXF1
uniprot id: A0A2Y9SW28
names: Subcellular Location Annotation
messages: Nucleus

9755:TAF13
gene id: 9755:TAF13
uniprot id: A0A2Y9SEC7
names: Subcellular Location Annotation
messages: Nucleus

9755:CCL24
gene id: 9755:CCL24
uniprot id: A0A2Y9ELI4
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.

9755:LOC102987847
gene id: 9755:LOC102987847
uniprot id: A0A2Y9SV91
uniprot id: A0A2Y9T1Z1
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

9755:PI4K2B
gene id: 9755:PI4K2B
uniprot id: A0A2Y9S923
uniprot id: A0A2Y9SFT4
uniprot id: A0A455BVP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
messages: Membrane

9755:PTS
gene id: 9755:PTS
uniprot id: A0A2Y9FQ15
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the PTPS family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin.

9755:PRMT7
gene id: 9755:PRMT7
uniprot id: A0A2Y9F1N2
uniprot id: A0A2Y9F2U8
uniprot id: A0A455AB25
uniprot id: A0A455AB60
uniprot id: A0A455AC84
uniprot id: A0A455AD84
uniprot id: A0A455AMN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.
messages: Nucleus
messages: cytosol

9755:NR1H3
gene id: 9755:NR1H3
uniprot id: A0A455C6V4
uniprot id: A0A455C6V9
uniprot id: A0A455C726
uniprot id: A0A455C7S6
uniprot id: A0A455C9G7
uniprot id: A0A455CBW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

9755:IL16
gene id: 9755:IL16
uniprot id: A0A2Y9F5P8
uniprot id: A0A455BSN0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homotetramer.
messages: Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4.
messages: Nucleus
messages: Secreted

9755:BRPF3
gene id: 9755:BRPF3
uniprot id: A0A2Y9F4J5
uniprot id: A0A455ART4
names: Subcellular Location Annotation
messages: Nucleus

9755:GCK
gene id: 9755:GCK
uniprot id: A0A2Y9FJL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hexokinase family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: cytosol

9755:MCM9
gene id: 9755:MCM9
uniprot id: A0A2Y9F3C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Chromosome
messages: Nucleus

9755:ACAP2
gene id: 9755:ACAP2
uniprot id: A0A2Y9SVZ3
uniprot id: A0A455BHV6
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

9755:HHIPL2
gene id: 9755:HHIPL2
uniprot id: A0A2Y9FNG4
names: Similarity
messages: Belongs to the HHIP family.

9755:LOC102974934
gene id: 9755:LOC102974934
uniprot id: A0A2Y9T2X2
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

9755:FRRS1
gene id: 9755:FRRS1
uniprot id: A0A455B7H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRRS1 family.
messages: Membrane

9755:POPDC3
gene id: 9755:POPDC3
uniprot id: A0A2Y9S1J4
names: Similarity
messages: Belongs to the popeye family.

9755:ZC3HAV1
gene id: 9755:ZC3HAV1
uniprot id: A0A2Y9FB01
names: Similarity
messages: Belongs to the ARTD/PARP family.

9755:LOC102980039
gene id: 9755:LOC102980039
uniprot id: A0A2Y9FIP3
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Membrane
messages: The TCR-CD3 complex is composed of a CD3D/CD3E and a CD3G/CD3E heterodimers that preferentially associate with TCRalpha and TCRbeta, respectively, to form TCRalpha/CD3E/CD3G and TCRbeta/CD3G/CD3E trimers. In turn, the hexamer interacts with CD3Z homodimer to form the TCR-CD3 complex. Alternatively, TCRalpha and TCRbeta can be replaced by TCRgamma and TCRdelta.

9755:SERP2
gene id: 9755:SERP2
uniprot id: A0A2Y9SSC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.
messages: Membrane

9755:RIBC1
gene id: 9755:RIBC1
uniprot id: A0A455APL8
uniprot id: A0A455AQZ0
names: Similarity
messages: Belongs to the RIB43A family.

9755:SVOPL
gene id: 9755:SVOPL
uniprot id: A0A2Y9T2Z1
names: Subcellular Location Annotation
messages: Membrane

9755:RBX1
gene id: 9755:RBX1
uniprot id: A0A2Y9SY00
names: Similarity
messages: Belongs to the RING-box family.

9755:HAPLN4
gene id: 9755:HAPLN4
uniprot id: A0A2Y9F8N6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9755:RAB38
gene id: 9755:RAB38
uniprot id: A0A2Y9EV63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

9755:ATG4B
gene id: 9755:ATG4B
uniprot id: A0A2Y9SP85
uniprot id: A0A455ATE3
uniprot id: A0A455B5X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

9755:NOBOX
gene id: 9755:NOBOX
uniprot id: A0A2Y9T6L0
names: Subcellular Location Annotation
messages: Nucleus

9755:HAL
gene id: 9755:HAL
uniprot id: A0A2Y9FJV6
names: Similarity
messages: Belongs to the PAL/histidase family.

9755:HOXD12
gene id: 9755:HOXD12
uniprot id: A0A2Y9EZG7
names: Subcellular Location Annotation
messages: Nucleus

9755:GAL3ST4
gene id: 9755:GAL3ST4
uniprot id: A0A2Y9SQZ2
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

9755:NLGN4X
gene id: 9755:NLGN4X
uniprot id: A0A2Y9FVN5
uniprot id: A0A2Y9FWP0
uniprot id: A0A2Y9S524
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

9755:USP36
gene id: 9755:USP36
uniprot id: A0A455C037
uniprot id: A0A455C492
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

9755:ELAVL3
gene id: 9755:ELAVL3
uniprot id: A0A2Y9EPQ1
uniprot id: A0A2Y9ER51
names: Similarity
messages: Belongs to the RRM elav family.

9755:SERPINI2
gene id: 9755:SERPINI2
uniprot id: A0A2Y9F438
uniprot id: A0A455APC2
names: Similarity
messages: Belongs to the serpin family.

9755:MANEA
gene id: 9755:MANEA
uniprot id: A0A2Y9F5F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

9755:HTR7
gene id: 9755:HTR7
uniprot id: A0A455AM46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9755:TRPV4
gene id: 9755:TRPV4
uniprot id: A0A455AI62
names: Subcellular Location Annotation
messages: Membrane

9755:CALHM2
gene id: 9755:CALHM2
uniprot id: A0A2Y9FU25
uniprot id: A0A2Y9FX55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

9755:CCND3
gene id: 9755:CCND3
uniprot id: A0A2Y9FDC1
uniprot id: A0A2Y9FDQ2
names: Similarity
messages: Belongs to the cyclin family.

9755:LOC102980808
gene id: 9755:LOC102980808
uniprot id: A0A2Y9FJ48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

9755:CDH8
gene id: 9755:CDH8
uniprot id: A0A455ACZ1
uniprot id: A0A455AQ73
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

9755:NIPAL2
gene id: 9755:NIPAL2
uniprot id: A0A2Y9RYY3
uniprot id: A0A2Y9RZA3
uniprot id: A0A2Y9S729
uniprot id: A0A455C4D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

9755:PFKFB2
gene id: 9755:PFKFB2
uniprot id: A0A455BK84
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

9755:HCK
gene id: 9755:HCK
uniprot id: A0A455CAH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

9755:USO1
gene id: 9755:USO1
uniprot id: A0A2Y9F1Y9
uniprot id: A0A455BFH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VDP/USO1/EDE1 family.
messages: Membrane

9755:SORL1
gene id: 9755:SORL1
uniprot id: A0A2Y9F600
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS10-related sortilin family. SORL1 subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Recycling endosome membrane
messages: Secreted
messages: multivesicular body membrane
messages: secretory vesicle membrane
messages: trans-Golgi network membrane

9755:YBEY
gene id: 9755:YBEY
uniprot id: A0A2Y9SJ46
uniprot id: A0A455BHY4
uniprot id: A0A455BIC7
uniprot id: A0A455BXN8
names: Similarity
messages: Belongs to the endoribonuclease YbeY family.

9755:C12H2orf49
gene id: 9755:C12H2orf49
uniprot id: A0A2Y9ET56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ashwin family.
messages: Nucleus

9755:EXOSC3
gene id: 9755:EXOSC3
uniprot id: A0A2Y9ES55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP40 family.
messages: Cytoplasm
messages: nucleolus

9755:VRK1
gene id: 9755:VRK1
uniprot id: A0A2Y9T7E1
uniprot id: A0A2Y9TDD6
uniprot id: A0A2Y9TFB3
names: Similarity
messages: Belongs to the protein kinase superfamily.

9755:ADM
gene id: 9755:ADM
uniprot id: A0A2Y9FD28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adrenomedullin family.
messages: Secreted

9755:TMEM86B
gene id: 9755:TMEM86B
uniprot id: A0A2Y9EI79
uniprot id: A0A2Y9EKA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

9755:PAH
gene id: 9755:PAH
uniprot id: A0A2Y9FXK9
uniprot id: A0A2Y9SY64
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

9755:PEX13
gene id: 9755:PEX13
uniprot id: A0A2Y9FKC0
names: Similarity
messages: Belongs to the peroxin-13 family.

9755:SLC7A9
gene id: 9755:SLC7A9
uniprot id: A0A2Y9EHH4
names: Subcellular Location Annotation
messages: Membrane

9755:AQP7
gene id: 9755:AQP7
uniprot id: A0A2Y9EZE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

9755:RBM17
gene id: 9755:RBM17
uniprot id: A0A2Y9FD61
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the spliceosome.
messages: Nucleus
messages: Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites.

9755:VSX2
gene id: 9755:VSX2
uniprot id: A0A2Y9F8C6
names: Subcellular Location Annotation
messages: Nucleus

9755:KCNS1
gene id: 9755:KCNS1
uniprot id: A0A2Y9T6D4
uniprot id: A0A455C0M7
names: Subcellular Location Annotation
messages: Membrane

9755:SLC6A12
gene id: 9755:SLC6A12
uniprot id: A0A2Y9F8B9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Basolateral cell membrane
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A12 subfamily.
messages: Cell membrane
messages: Interacts with LIN7C.
messages: Lateral cell membrane
messages: Membrane

9755:LOC102979369
gene id: 9755:LOC102979369
uniprot id: A0A2Y9EK85
uniprot id: A0A455BQ96
uniprot id: A0A455C5E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCTS1 family.
messages: Cytoplasm

9755:NUDT3
gene id: 9755:NUDT3
uniprot id: A0A2Y9FE21
uniprot id: A0A455ADJ3
uniprot id: A0A455AF40
uniprot id: A0A455AR98
names: Similarity
messages: Belongs to the Nudix hydrolase family. DIPP subfamily.

9755:ACAD10
gene id: 9755:ACAD10
uniprot id: A0A455AWZ8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

9755:KCNQ1
gene id: 9755:KCNQ1
uniprot id: A0A2Y9TDV2
uniprot id: A0A455ADJ0
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the potassium channel family. KQT (TC 1.A.1.15) subfamily. Kv7.1/KCNQ1 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum
messages: Lateral cell membrane
messages: Membrane
messages: Membrane raft

9755:STAG1
gene id: 9755:STAG1
uniprot id: A0A2Y9EJ28
uniprot id: A0A2Y9TFC6
uniprot id: A0A455B8I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

9755:HSBP1L1
gene id: 9755:HSBP1L1
uniprot id: A0A2Y9TKP4
uniprot id: A0A455AKF2
names: Similarity
messages: Belongs to the HSBP1 family.

9755:ZFYVE28
gene id: 9755:ZFYVE28
uniprot id: A0A455BHL4
names: Similarity
messages: Belongs to the lst-2 family.

9755:NPHP1
gene id: 9755:NPHP1
uniprot id: A0A2Y9T3Q9
names: Subcellular Location Annotation
messages: Membrane

9755:MBOAT1
gene id: 9755:MBOAT1
uniprot id: A0A2Y9SN15
uniprot id: A0A455AEL3
uniprot id: A0A455AH01
names: Subcellular Location Annotation
messages: Membrane

9755:FSHB
gene id: 9755:FSHB
uniprot id: A0A2Y9S772
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

9755:ABCD3
gene id: 9755:ABCD3
uniprot id: A0A2Y9SA15
uniprot id: A0A2Y9SGS8
uniprot id: A0A455B7J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.
messages: Membrane
messages: Peroxisome membrane

9755:TEX10
gene id: 9755:TEX10
uniprot id: A0A2Y9SZ93
names: Similarity
messages: Belongs to the IPI1/TEX10 family.

9755:AMBP
gene id: 9755:AMBP
uniprot id: A0A2Y9EWU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Endoplasmic reticulum
messages: In the N-terminal section; belongs to the calycin superfamily. Lipocalin family.
messages: Kunitz-type serine protease inhibitor. Has high catalytic efficiency for F10/blood coagulation factor Xa and may act as an anticoagulant by inhibiting prothrombin activation. Inhibits trypsin and mast cell CMA1/chymase and tryptase proteases.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Monomer. Also occurs as a complex with tryptase in mast cells.
messages: Nucleus membrane
messages: cytosol
messages: extracellular matrix

9755:GAREM2
gene id: 9755:GAREM2
uniprot id: A0A2Y9SER9
names: Similarity
messages: Belongs to the GAREM family.

9755:ACTRT2
gene id: 9755:ACTRT2
uniprot id: A0A2Y9FLR4
names: Similarity
messages: Belongs to the actin family.

9755:ELL2
gene id: 9755:ELL2
uniprot id: A0A2Y9EWJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

9755:ETV4
gene id: 9755:ETV4
uniprot id: A0A2Y9FPH4
uniprot id: A0A2Y9FR89
uniprot id: A0A2Y9FS46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9755:CHRDL2
gene id: 9755:CHRDL2
uniprot id: A0A2Y9FEN7
names: Subcellular Location Annotation
messages: Secreted

9755:TRAF6
gene id: 9755:TRAF6
uniprot id: A0A2Y9ERK4
uniprot id: A0A2Y9ERN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family. A subfamily.
messages: Lipid droplet
messages: Nucleus
messages: cell cortex

9755:PRDM15
gene id: 9755:PRDM15
uniprot id: A0A2Y9SC16
uniprot id: A0A455BHP2
names: Subcellular Location Annotation
messages: Nucleus

9755:KMT2D
gene id: 9755:KMT2D
uniprot id: A0A2Y9ERW0
uniprot id: A0A455BDW4
uniprot id: A0A455BDW9
uniprot id: A0A455BEH5
uniprot id: A0A455BEI1
uniprot id: A0A455BEI9
uniprot id: A0A455BTJ2
names: Subcellular Location Annotation
messages: Nucleus

9755:CADM1
gene id: 9755:CADM1
uniprot id: A0A2Y9FMC5
uniprot id: A0A2Y9FMW0
names: Similarity
messages: Belongs to the nectin family.

9755:MAP2K4
gene id: 9755:MAP2K4
uniprot id: A0A2Y9SXK3
uniprot id: A0A2Y9T1J9
names: Similarity
messages: Belongs to the protein kinase superfamily.

9755:B3GALT6
gene id: 9755:B3GALT6
uniprot id: A0A2Y9SXZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9755:DYNLT1
gene id: 9755:DYNLT1
uniprot id: A0A2Y9SIJ9
uniprot id: A0A2Y9SRA2
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

9755:LOC102992750
gene id: 9755:LOC102992750
uniprot id: A0A2Y9S2H0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:PLPP4
gene id: 9755:PLPP4
uniprot id: A0A2Y9SLC6
uniprot id: A0A455AM66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

9755:PTPN14
gene id: 9755:PTPN14
uniprot id: A0A2Y9EG52
uniprot id: A0A2Y9EHB8
uniprot id: A0A455B6K8
uniprot id: A0A455B8E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

9755:AK2
gene id: 9755:AK2
uniprot id: A0A2Y9FJR7
uniprot id: A0A2Y9FKQ4
uniprot id: A0A2Y9SSD0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Belongs to the adenylate kinase family. AK2 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Mitochondrion intermembrane space
messages: Monomer.

9755:IMPA1
gene id: 9755:IMPA1
uniprot id: A0A2Y9FME5
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

9755:MCM7
gene id: 9755:MCM7
uniprot id: A0A2Y9EZ14
uniprot id: A0A2Y9EZ90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Nucleus

9755:TBK1
gene id: 9755:TBK1
uniprot id: A0A2Y9SQL8
uniprot id: A0A455BB00
uniprot id: A0A455BBQ7
names: Subcellular Location Annotation
messages: Cytoplasm

9755:MARK2
gene id: 9755:MARK2
uniprot id: A0A455C5M3
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

9755:FGF16
gene id: 9755:FGF16
uniprot id: A0A2Y9T6T6
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9755:MMGT1
gene id: 9755:MMGT1
uniprot id: A0A2Y9EDA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane magnesium transporter (TC 1.A.67) family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

9755:TEKT3
gene id: 9755:TEKT3
uniprot id: A0A455C296
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

9755:CTNNA2
gene id: 9755:CTNNA2
uniprot id: A0A2Y9TC61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction

9755:LOXL1
gene id: 9755:LOXL1
uniprot id: A0A2Y9EYD6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

9755:MEGF11
gene id: 9755:MEGF11
uniprot id: A0A2Y9EZL4
uniprot id: A0A2Y9T9D0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:SLC35B1
gene id: 9755:SLC35B1
uniprot id: A0A2Y9FSA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

9755:LOC102985903
gene id: 9755:LOC102985903
uniprot id: A0A2Y9SZN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the noggin family.
messages: Homodimer.
messages: Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.
messages: Secreted

9755:IFRD2
gene id: 9755:IFRD2
uniprot id: A0A455AGA3
names: Similarity
messages: Belongs to the IFRD family.

9755:MBTD1
gene id: 9755:MBTD1
uniprot id: A0A2Y9F725
uniprot id: A0A2Y9F7E1
uniprot id: A0A2Y9F7F8
uniprot id: A0A2Y9F8Z8
uniprot id: A0A2Y9T938
uniprot id: A0A2Y9TDP4
names: Subcellular Location Annotation
messages: Nucleus

9755:FGF20
gene id: 9755:FGF20
uniprot id: A0A2Y9FIC2
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9755:LSM2
gene id: 9755:LSM2
uniprot id: A0A2Y9EWM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: Nucleus

9755:HAT1
gene id: 9755:HAT1
uniprot id: A0A2Y9FA06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAT1 family.
messages: Catalytic subunit of the type B histone acetyltransferase (HAT) complex, composed of RBBP7 and HAT1. Interacts with histones H4 and H2A.
messages: Histone acetyltransferase that plays a role in different biological processes including cell cycle progression, glucose metabolism, histone production or DNA damage repair. Coordinates histone production and acetylation via H4 promoter binding. Acetylates histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, histone H2A at 'Lys-5' (H2AK5ac).

9755:TNIP2
gene id: 9755:TNIP2
uniprot id: A0A455BGZ7
names: Subcellular Location Annotation
messages: Cytoplasm

9755:LIFR
gene id: 9755:LIFR
uniprot id: A0A455BI71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

9755:SOX1
gene id: 9755:SOX1
uniprot id: A0A2Y9SKR7
uniprot id: A0A2Y9STC0
names: Subcellular Location Annotation
messages: Nucleus

9755:GEMIN2
gene id: 9755:GEMIN2
uniprot id: A0A2Y9F8T7
uniprot id: A0A455BRF8
uniprot id: A0A455BRG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gemin-2 family.
messages: Cytoplasm
messages: Part of the core SMN complex.
messages: The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs.

9755:SOX21
gene id: 9755:SOX21
uniprot id: A0A2Y9STB0
names: Subcellular Location Annotation
messages: Nucleus

9755:MAP7D3
gene id: 9755:MAP7D3
uniprot id: A0A2Y9T2Y8
names: Similarity
messages: Belongs to the MAP7 family.

9755:LOC102988390
gene id: 9755:LOC102988390
uniprot id: A0A2Y9RWK9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:PREPL
gene id: 9755:PREPL
uniprot id: A0A2Y9EYB4
uniprot id: A0A2Y9SF73
uniprot id: A0A455BUA4
uniprot id: A0A455BUA5
names: Similarity
messages: Belongs to the peptidase S9A family.

9755:ARPP19
gene id: 9755:ARPP19
uniprot id: A0A2Y9T4R6
uniprot id: A0A455BQG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.

9755:STEAP4
gene id: 9755:STEAP4
uniprot id: A0A2Y9EYR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

9755:SLC34A2
gene id: 9755:SLC34A2
uniprot id: A0A455BU21
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Membrane

9755:TRPC5
gene id: 9755:TRPC5
uniprot id: A0A2Y9F516
names: Subcellular Location Annotation
messages: Membrane

9755:LOC102975583
gene id: 9755:LOC102975583
uniprot id: A0A455AKE3
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

9755:PPARGC1B
gene id: 9755:PPARGC1B
uniprot id: A0A455BJM1
uniprot id: A0A455BZH3
names: Subcellular Location Annotation
messages: Nucleus

9755:NIBAN2
gene id: 9755:NIBAN2
uniprot id: A0A2Y9EFU4
uniprot id: A0A2Y9EGH7
uniprot id: A0A2Y9EHT7
names: Similarity
messages: Belongs to the Niban family.

9755:LOC102982282
gene id: 9755:LOC102982282
uniprot id: A0A455B0Y5
names: Similarity
messages: Belongs to the peptidase S1C family.

9755:FAM227B
gene id: 9755:FAM227B
uniprot id: A0A2Y9S6I7
names: Similarity
messages: Belongs to the FAM227 family.

9755:FADS1
gene id: 9755:FADS1
uniprot id: A0A2Y9ENT2
uniprot id: A0A2Y9ENW9
uniprot id: A0A2Y9EQE3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

9755:CORIN
gene id: 9755:CORIN
uniprot id: A0A2Y9TDP5
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:RDH14
gene id: 9755:RDH14
uniprot id: A0A2Y9SF05
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9755:CCSER1
gene id: 9755:CCSER1
uniprot id: A0A2Y9T0R5
uniprot id: A0A455BF53
names: Similarity
messages: Belongs to the CCSER family.

9755:ALDH1A2
gene id: 9755:ALDH1A2
uniprot id: A0A2Y9F081
uniprot id: A0A455BV04
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

9755:CARMIL3
gene id: 9755:CARMIL3
uniprot id: A0A455C684
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CARMIL family.
messages: Cytoplasm

9755:NDUFS8
gene id: 9755:NDUFS8
uniprot id: A0A455C7Y6
uniprot id: A0A455C8E2
names: Similarity
messages: Belongs to the complex I 23 kDa subunit family.

9755:LOC102991176
gene id: 9755:LOC102991176
uniprot id: A0A2Y9ENT5
uniprot id: A0A2Y9SMW8
uniprot id: A0A455AG20
names: Subcellular Location Annotation
messages: Nucleus

9755:ITGB4
gene id: 9755:ITGB4
uniprot id: A0A2Y9ED97
uniprot id: A0A2Y9EDM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

9755:GRIK3
gene id: 9755:GRIK3
uniprot id: A0A2Y9EKB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

9755:LOC102982923
gene id: 9755:LOC102982923
uniprot id: A0A2Y9SIP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

9755:ANTXR1
gene id: 9755:ANTXR1
uniprot id: A0A2Y9FMA6
uniprot id: A0A2Y9FMG1
uniprot id: A0A2Y9FMU1
uniprot id: A0A2Y9FNX1
uniprot id: A0A455BUJ3
uniprot id: A0A455BXA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

9755:LOC102984256
gene id: 9755:LOC102984256
uniprot id: A0A455BM51
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:SLC5A7
gene id: 9755:SLC5A7
uniprot id: A0A2Y9F5P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

9755:FNIP1
gene id: 9755:FNIP1
uniprot id: A0A2Y9ERS3
uniprot id: A0A2Y9ETN7
uniprot id: A0A455BJI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNIP family.
messages: Lysosome membrane
messages: Membrane

9755:LOC102994530
gene id: 9755:LOC102994530
uniprot id: A0A2Y9F239
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:QSOX2
gene id: 9755:QSOX2
uniprot id: A0A2Y9SY59
names: Function
names: Similarity
messages: Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.
messages: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide.

9755:SYN1
gene id: 9755:SYN1
uniprot id: A0A2Y9EJW9
uniprot id: A0A2Y9EKH3
names: Similarity
messages: Belongs to the synapsin family.

9755:UBA1
gene id: 9755:UBA1
uniprot id: A0A2Y9ELV9
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

9755:E2F7
gene id: 9755:E2F7
uniprot id: A0A2Y9FDT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

9755:EMX1
gene id: 9755:EMX1
uniprot id: A0A2Y9EWC6
uniprot id: A0A2Y9TGP7
names: Subcellular Location Annotation
messages: Nucleus

9755:RPSA
gene id: 9755:RPSA
uniprot id: A0A2Y9FEB2
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acylated. Acylation may be a prerequisite for conversion of the monomeric 37 kDa laminin receptor precursor (37LRP) to the mature dimeric 67 kDa laminin receptor (67LR), and may provide a mechanism for membrane association.
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Cell membrane
messages: Cleaved by stromelysin-3 (ST3) at the cell surface. Cleavage by stromelysin-3 may be a mechanism to alter cell-extracellular matrix interactions.
messages: Cytoplasm
messages: Monomer (37LRP) and homodimer (67LR). Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Interacts with RPS21. Interacts with several laminins including at least LAMB1. Interacts with MDK. The mature dimeric form interacts with PPP1R16B (via its fourth ankyrin repeat). Interacts with PPP1CA only in the presence of PPP1R16B.
messages: Nucleus
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. Acts as a PPP1R16B-dependent substrate of PPP1CA.
messages: This protein appears to have acquired a second function as a laminin receptor specifically in the vertebrate lineage.

9755:SGK1
gene id: 9755:SGK1
uniprot id: A0A2Y9SPT4
uniprot id: A0A2Y9SRL0
names: Similarity
messages: Belongs to the protein kinase superfamily.

9755:PRKAB2
gene id: 9755:PRKAB2
uniprot id: A0A2Y9FC21
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

9755:ESR1
gene id: 9755:ESR1
uniprot id: A0A455BNS6
uniprot id: A0A455BNT1
uniprot id: A0A455BNU5
uniprot id: A0A455BS19
uniprot id: A0A455C3W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family.
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Binds DNA as a homodimer.
messages: Membrane
messages: Nucleus
messages: The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.

9755:PLCB4
gene id: 9755:PLCB4
uniprot id: A0A2Y9EU48
uniprot id: A0A455C156
names: Cofactor
names: Function
messages: Binds 1 Ca(2+) ion per subunit.
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

9755:CCNYL1
gene id: 9755:CCNYL1
uniprot id: A0A2Y9EX31
uniprot id: A0A2Y9EY43
names: Similarity
messages: Belongs to the cyclin family. Cyclin Y subfamily.

9755:LOC102995721
gene id: 9755:LOC102995721
uniprot id: A0A2Y9EPM0
names: Subcellular Location Annotation
messages: Membrane

9755:CANX
gene id: 9755:CANX
uniprot id: A0A2Y9F1N6
names: Similarity
messages: Belongs to the calreticulin family.

9755:GJC2
gene id: 9755:GJC2
uniprot id: A0A455C661
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9755:LOC102992814
gene id: 9755:LOC102992814
uniprot id: A0A2Y9EHW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

9755:LOC102986579
gene id: 9755:LOC102986579
uniprot id: A0A2Y9FB51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIIc family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits, encoded in the mitochondrial DNA, and 11 supernumerary subunits, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

9755:SNRPE
gene id: 9755:SNRPE
uniprot id: A0A2Y9EZR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. As part of the U7 snRNP it is involved in histone 3'-end processing.
messages: cytosol

9755:SLC25A47
gene id: 9755:SLC25A47
uniprot id: A0A2Y9EUS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9755:FAM174B
gene id: 9755:FAM174B
uniprot id: A0A2Y9S3K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM174 family.
messages: Membrane

9755:EDEM1
gene id: 9755:EDEM1
uniprot id: A0A2Y9SQ92
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

9755:PHKA2
gene id: 9755:PHKA2
uniprot id: A0A2Y9EQ66
uniprot id: A0A2Y9EQ94
uniprot id: A0A2Y9ERS8
uniprot id: A0A455APV5
uniprot id: A0A455APW0
uniprot id: A0A455AQ44
uniprot id: A0A455ARG6
uniprot id: A0A455ARH0
uniprot id: A0A455AS08
uniprot id: A0A455B3T9
uniprot id: A0A455B3U6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

9755:TTC38
gene id: 9755:TTC38
uniprot id: A0A2Y9FQU4
uniprot id: A0A455BC19
uniprot id: A0A455BCS8
names: Similarity
messages: Belongs to the TTC38 family.

9755:TMEM165
gene id: 9755:TMEM165
uniprot id: A0A2Y9FEU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

9755:VPS4B
gene id: 9755:VPS4B
uniprot id: A0A2Y9ENN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

9755:LOC102987744
gene id: 9755:LOC102987744
uniprot id: A0A2Y9SDU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9755:ATP6V0A4
gene id: 9755:ATP6V0A4
uniprot id: A0A2Y9FB64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

9755:LOC112065901
gene id: 9755:LOC112065901
uniprot id: A0A2Y9SYE2
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

9755:PARK7
gene id: 9755:PARK7
uniprot id: A0A2Y9F7N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C56 family.
messages: Membrane raft

9755:UNC13B
gene id: 9755:UNC13B
uniprot id: A0A2Y9F0M0
uniprot id: A0A455BLL8
uniprot id: A0A455C0X0
names: Subcellular Location Annotation
messages: Cytoplasm

9755:CD99
gene id: 9755:CD99
uniprot id: A0A2Y9RXG5
names: Similarity
messages: Belongs to the CD99 family.

9755:LOC102973949
gene id: 9755:LOC102973949
uniprot id: A0A2Y9SX44
uniprot id: A0A2Y9SZN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

9755:TRIT1
gene id: 9755:TRIT1
uniprot id: A0A2Y9FC66
names: Function
names: Similarity
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37.

9755:NFS1
gene id: 9755:NFS1
uniprot id: A0A2Y9T044
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

9755:TOMM7
gene id: 9755:TOMM7
uniprot id: A0A2Y9TB38
uniprot id: A0A2Y9TFK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom7 family.
messages: Membrane
messages: Mitochondrion outer membrane

9755:CERT1
gene id: 9755:CERT1
uniprot id: A0A2Y9T690
uniprot id: A0A2Y9TE61
uniprot id: A0A2Y9TEG5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus

9755:HDAC9
gene id: 9755:HDAC9
uniprot id: A0A2Y9EPS5
uniprot id: A0A2Y9EPT0
uniprot id: A0A2Y9T2C5
uniprot id: A0A2Y9T2E1
uniprot id: A0A2Y9T8H7
uniprot id: A0A2Y9T8I4
uniprot id: A0A2Y9TAQ6
uniprot id: A0A455BB26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

9755:RPL21
gene id: 9755:RPL21
uniprot id: A0A455BXT3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

9755:APP
gene id: 9755:APP
uniprot id: A0A2Y9EXI8
uniprot id: A0A2Y9EXK6
uniprot id: A0A2Y9EY25
uniprot id: A0A2Y9EZH0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Cell membrane
messages: Cell surface
messages: Cytoplasmic vesicle
messages: Early endosome
messages: Endosome
messages: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis.
messages: Golgi apparatus
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-APP binds TNFRSF21 triggering caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6).
messages: Nucleus
messages: Perikaryon
messages: Secreted
messages: The gamma-CTF peptides as well as the caspase-cleaved peptides, including C31, are potent enhancers of neuronal apoptosis.
messages: Vesicle
messages: clathrin-coated pit
messages: growth cone

9755:HNRNPA3
gene id: 9755:HNRNPA3
uniprot id: A0A2Y9SHV3
names: Subcellular Location Annotation
messages: Nucleus

9755:HIP1R
gene id: 9755:HIP1R
uniprot id: A0A2Y9SC99
names: Similarity
messages: Belongs to the SLA2 family.

9755:ANP32E
gene id: 9755:ANP32E
uniprot id: A0A2Y9EVB3
uniprot id: A0A2Y9EWE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANP32 family.
messages: Multifunctional protein that is involved in the regulation of many processes.
messages: Nucleus

9755:LOC102987795
gene id: 9755:LOC102987795
uniprot id: A0A2Y9F0G9
uniprot id: A0A2Y9F0M8
uniprot id: A0A2Y9F0V6
uniprot id: A0A2Y9F1P8
names: Similarity
messages: Belongs to the peptidase C14A family.

9755:SMAD2
gene id: 9755:SMAD2
uniprot id: A0A2Y9TEE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

9755:ARL6
gene id: 9755:ARL6
uniprot id: A0A2Y9SCT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: cilium membrane

9755:STRN
gene id: 9755:STRN
uniprot id: A0A2Y9S748
uniprot id: A0A2Y9SDT7
uniprot id: A0A455BU13
uniprot id: A0A455BUQ6
uniprot id: A0A455BXH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

9755:CD151
gene id: 9755:CD151
uniprot id: A0A2Y9EVI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9755:LOC102978706
gene id: 9755:LOC102978706
uniprot id: A0A2Y9FAJ4
names: Subcellular Location Annotation
messages: Membrane

9755:SLC30A7
gene id: 9755:SLC30A7
uniprot id: A0A2Y9F4Y2
uniprot id: A0A2Y9F6N0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Functions as a zinc transporter.
messages: Homooligomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: trans-Golgi network membrane

9755:SYNM
gene id: 9755:SYNM
uniprot id: A0A2Y9F7T9
uniprot id: A0A2Y9F9L3
names: Similarity
messages: Belongs to the intermediate filament family.

9755:LOC102988394
gene id: 9755:LOC102988394
uniprot id: A0A2Y9FGT9
names: Similarity
messages: Belongs to the PRR23 family.

9755:CHAT
gene id: 9755:CHAT
uniprot id: A0A2Y9FU34
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

9755:INS
gene id: 9755:INS
uniprot id: A0A2Y9SAK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the insulin family.
messages: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
messages: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
messages: Secreted

9755:CFAP107
gene id: 9755:CFAP107
uniprot id: A0A2Y9FUG4
names: Function
names: Subcellular Location Annotation
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.
messages: cilium axoneme

9755:SLBP
gene id: 9755:SLBP
uniprot id: A0A2Y9S9T8
names: Similarity
messages: Belongs to the SLBP family.

9755:PPP1R14D
gene id: 9755:PPP1R14D
uniprot id: A0A455BU48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP1 inhibitor family.
messages: Cytoplasm
messages: Inhibitor of PPP1CA.

9755:FABP2
gene id: 9755:FABP2
uniprot id: A0A2Y9FF18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm

9755:PTPRD
gene id: 9755:PTPRD
uniprot id: A0A2Y9SVD7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.

9755:DYRK1A
gene id: 9755:DYRK1A
uniprot id: A0A2Y9EWY3
uniprot id: A0A2Y9SBL3
uniprot id: A0A455BXE2
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

9755:HNRNPH2
gene id: 9755:HNRNPH2
uniprot id: A0A2Y9FBN6
names: Subcellular Location Annotation
messages: nucleoplasm

9755:SYNE2
gene id: 9755:SYNE2
uniprot id: A0A2Y9TEC5
uniprot id: A0A2Y9TGC3
uniprot id: A0A2Y9TI45
uniprot id: A0A2Y9TI50
uniprot id: A0A2Y9TK48
uniprot id: A0A2Y9TK60
uniprot id: A0A455BS27
names: Similarity
messages: Belongs to the nesprin family.

9755:LOC102982192
gene id: 9755:LOC102982192
uniprot id: A0A2Y9SA70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

9755:ATG2A
gene id: 9755:ATG2A
uniprot id: A0A455C731
uniprot id: A0A455C7T1
uniprot id: A0A455CBW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG2 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Preautophagosomal structure membrane

9755:PROKR1
gene id: 9755:PROKR1
uniprot id: A0A2Y9FNW7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9755:FAM76B
gene id: 9755:FAM76B
uniprot id: A0A2Y9EHM7
uniprot id: A0A2Y9RX31
uniprot id: A0A455C7T5
uniprot id: A0A455C7Z0
uniprot id: A0A455C9V3
names: Similarity
messages: Belongs to the FAM76 family.

9755:MKI67
gene id: 9755:MKI67
uniprot id: A0A2Y9SF85
names: Subcellular Location Annotation
messages: Nucleus

9755:ILKAP
gene id: 9755:ILKAP
uniprot id: A0A2Y9F4R6
uniprot id: A0A2Y9SSI0
uniprot id: A0A455AQJ9
uniprot id: A0A455AQT7
uniprot id: A0A455AQU2
uniprot id: A0A455ASP7
names: Similarity
messages: Belongs to the PP2C family.

9755:FZD10
gene id: 9755:FZD10
uniprot id: A0A2Y9SHP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

9755:TCF7L1
gene id: 9755:TCF7L1
uniprot id: A0A2Y9T5M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

9755:LOC102979676
gene id: 9755:LOC102979676
uniprot id: A0A2Y9F5G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9755:EXOSC2
gene id: 9755:EXOSC2
uniprot id: A0A2Y9T293
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP4 family.
messages: Cytoplasm

9755:SLC39A6
gene id: 9755:SLC39A6
uniprot id: A0A2Y9SJW2
names: Subcellular Location Annotation
messages: Membrane

9755:EDEM2
gene id: 9755:EDEM2
uniprot id: A0A2Y9FIB9
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

9755:VPS13C
gene id: 9755:VPS13C
uniprot id: A0A2Y9T6U2
uniprot id: A0A455BPH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS13 family.
messages: Lipid droplet

9755:FZD5
gene id: 9755:FZD5
uniprot id: A0A2Y9EX37
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:ERCC3
gene id: 9755:ERCC3
uniprot id: A0A2Y9S3R0
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

9755:DENND5B
gene id: 9755:DENND5B
uniprot id: A0A455BDZ2
names: Caution
names: Similarity
messages: Belongs to the RAB6IP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:SCAI
gene id: 9755:SCAI
uniprot id: A0A2Y9T2D2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAI family.
messages: Cytoplasm
messages: Interacts with DIAPH1. Forms a nuclear ternary complex with MRTFA and SRF.
messages: Nucleus
messages: Tumor suppressor which functions to suppress MRTFA-induced SRF transcriptional activity.

9755:NCAPG
gene id: 9755:NCAPG
uniprot id: A0A2Y9EGN1
uniprot id: A0A2Y9SFX0
uniprot id: A0A455BGP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND3 (condensin subunit 3) family.
messages: Chromosome

9755:PDIA4
gene id: 9755:PDIA4
uniprot id: A0A2Y9FGV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

9755:HPSE
gene id: 9755:HPSE
uniprot id: A0A2Y9S152
names: Similarity
messages: Belongs to the glycosyl hydrolase 79 family.

9755:BORCS5
gene id: 9755:BORCS5
uniprot id: A0A2Y9F2Y3
uniprot id: A0A455BCX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS5 family.
messages: Lysosome membrane
messages: Membrane

9755:DLG2
gene id: 9755:DLG2
uniprot id: A0A455CBT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: Membrane

9755:KEF67 p11
gene id: 9755:KEF67_p11
uniprot id: Q9MET4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

9755:LOC102986540
gene id: 9755:LOC102986540
uniprot id: A0A2Y9FPZ0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

9755:FAM161A
gene id: 9755:FAM161A
uniprot id: A0A2Y9TEM4
uniprot id: A0A2Y9TID4
uniprot id: A0A2Y9TKA2
names: Similarity
messages: Belongs to the FAM161 family.

9755:TMEM161B
gene id: 9755:TMEM161B
uniprot id: A0A2Y9FG51
uniprot id: A0A2Y9SCR6
uniprot id: A0A2Y9SGL9
uniprot id: A0A2Y9SKZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM161 family.
messages: Membrane

9755:ART3
gene id: 9755:ART3
uniprot id: A0A455BG58
uniprot id: A0A455BV70
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

9755:WDR12
gene id: 9755:WDR12
uniprot id: A0A2Y9F0K5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat WDR12/YTM1 family.
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

9755:CDKN2AIPNL
gene id: 9755:CDKN2AIPNL
uniprot id: A0A2Y9EQN7
uniprot id: A0A2Y9ER14
uniprot id: A0A2Y9ERZ3
uniprot id: A0A2Y9ES34
names: Similarity
messages: Belongs to the CARF family.

9755:CSN3
gene id: 9755:CSN3
uniprot id: A0A2Y9FC33
uniprot id: A0A2Y9TDR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kappa-casein family.
messages: Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk.
messages: Secreted

9755:LOC102976573
gene id: 9755:LOC102976573
uniprot id: A0A2Y9EKW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

9755:LOC102973874
gene id: 9755:LOC102973874
uniprot id: A0A2Y9STI3
names: Subcellular Location Annotation
messages: Nucleus

9755:SLC6A14
gene id: 9755:SLC6A14
uniprot id: A0A2Y9F9R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

9755:TAFA3
gene id: 9755:TAFA3
uniprot id: A0A2Y9F370
uniprot id: A0A2Y9F3B9
names: Similarity
messages: Belongs to the TAFA family.

9755:NDOR1
gene id: 9755:NDOR1
uniprot id: A0A2Y9EIW8
uniprot id: A0A2Y9EK74
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Interacts with CIAPIN1; as part of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of CIAPIN1, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. It can also reduce the [2Fe-2S] cluster of CISD1 and activate this protein implicated in Fe/S cluster repair.
messages: perinuclear region

9755:DDR1
gene id: 9755:DDR1
uniprot id: A0A2Y9EQL1
uniprot id: A0A455AF22
names: Subcellular Location Annotation
messages: Membrane

9755:LOC102985237
gene id: 9755:LOC102985237
uniprot id: A0A2Y9FP41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

9755:LOC102983447
gene id: 9755:LOC102983447
uniprot id: A0A455BDJ0
names: Subcellular Location Annotation
messages: Nucleus

9755:MARK1
gene id: 9755:MARK1
uniprot id: A0A2Y9T5X7
uniprot id: A0A2Y9T9F1
uniprot id: A0A2Y9TBX0
uniprot id: A0A2Y9TBX7
uniprot id: A0A2Y9TE11
uniprot id: A0A455B831
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

9755:FAM120B
gene id: 9755:FAM120B
uniprot id: A0A2Y9SR81
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

9755:MALSU1
gene id: 9755:MALSU1
uniprot id: A0A2Y9T5V7
uniprot id: A0A455BB49
names: Similarity
messages: Belongs to the Iojap/RsfS family.

9755:EYS
gene id: 9755:EYS
uniprot id: A0A2Y9TIV9
uniprot id: A0A2Y9TJI3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:TGFB2
gene id: 9755:TGFB2
uniprot id: A0A2Y9FLC0
uniprot id: A0A2Y9FMV0
uniprot id: A0A2Y9FNU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.
messages: extracellular matrix

9755:LOC102990569
gene id: 9755:LOC102990569
uniprot id: A0A2Y9SG73
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:NDUFC1
gene id: 9755:NDUFC1
uniprot id: A0A2Y9EJ63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFC1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9755:EHD1
gene id: 9755:EHD1
uniprot id: A0A2Y9EVV2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

9755:TADA1
gene id: 9755:TADA1
uniprot id: A0A2Y9F6S6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TADA1 family.
messages: Component of the STAGA transcription coactivator-HAT complex, at least composed of SUPT3H, GCN5L2, TAF5L, TAF6L, SUPT7L, TADA3L, TAD1L, TAF10, TAF12, TRRAP and TAF9.
messages: Nucleus
messages: Probably involved in transcriptional regulation.

9755:TTI2
gene id: 9755:TTI2
uniprot id: A0A2Y9FCP7
names: Similarity
messages: Belongs to the TTI2 family.

9755:MCU
gene id: 9755:MCU
uniprot id: A0A2Y9THW9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCU (TC 1.A.77) family.
messages: Forms a well-packed pentamer with an overall cylindrical shape. The inner core of the pentamer is formed with the second transmembrane region and the second coiled-coil region: while the transmembrane regions pack into a five-helix bundle having a largely polar pore across the membrane, the coiled-coil outside the membrane forms a pentamer with a hydrophobic core. The inner core is wrapped by the first transmembrane region through contacts between the first and the second transmembrane regions. The second transmembrane is followed by the inner juxtamembrane region (IJMH) that orients at a wide angle relative to the second transmembrane. The two core domains are held together on the periphery by the outer juxtamembrane helix (OJMH).
messages: Membrane
messages: Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
messages: Mitochondrion inner membrane

9755:ATP5F1A
gene id: 9755:ATP5F1A
uniprot id: A0A2Y9EXN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

9755:LOC102986213
gene id: 9755:LOC102986213
uniprot id: A0A455APV8
names: Similarity
names: Subunit
messages: Belongs to the TRAPPC13 family.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.

9755:FLVCR1
gene id: 9755:FLVCR1
uniprot id: A0A2Y9EXC9
names: Subcellular Location Annotation
messages: Membrane

9755:TIMP3
gene id: 9755:TIMP3
uniprot id: A0A2Y9EHF4
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

9755:CCSER2
gene id: 9755:CCSER2
uniprot id: A0A2Y9EJJ8
uniprot id: A0A2Y9EJK2
uniprot id: A0A2Y9EK84
uniprot id: A0A2Y9ELH5
uniprot id: A0A2Y9ELH8
uniprot id: A0A2Y9ELM8
uniprot id: A0A455AL85
uniprot id: A0A455AN16
uniprot id: A0A455ANA4
names: Similarity
messages: Belongs to the CCSER family.

9755:SNRPB
gene id: 9755:SNRPB
uniprot id: A0A2Y9FN00
uniprot id: A0A455CAU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP SmB/SmN family.
messages: Nucleus

9755:HCFC1
gene id: 9755:HCFC1
uniprot id: A0A2Y9F1V9
uniprot id: A0A2Y9F231
uniprot id: A0A2Y9F3T8
uniprot id: A0A455AMR8
uniprot id: A0A455AMS1
uniprot id: A0A455AMZ2
uniprot id: A0A455APF6
uniprot id: A0A455APG0
uniprot id: A0A455APT8
uniprot id: A0A455B1J0
names: Subcellular Location Annotation
messages: Nucleus

9755:TMC6
gene id: 9755:TMC6
uniprot id: A0A455C119
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

9755:LOC102983042
gene id: 9755:LOC102983042
uniprot id: A0A2Y9SAM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
messages: Peroxisome

9755:ANXA10
gene id: 9755:ANXA10
uniprot id: A0A2Y9F712
names: Similarity
messages: Belongs to the annexin family.

9755:CAB39
gene id: 9755:CAB39
uniprot id: A0A2Y9FMR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

9755:EPC1
gene id: 9755:EPC1
uniprot id: A0A2Y9S0I3
uniprot id: A0A455C819
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enhancer of polycomb family.
messages: Nucleus

9755:CPLX1
gene id: 9755:CPLX1
uniprot id: A0A2Y9S8Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

9755:SLC6A4
gene id: 9755:SLC6A4
uniprot id: A0A2Y9T1I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A4 subfamily.
messages: Cell membrane
messages: Endomembrane system
messages: Endosome membrane
messages: Membrane
messages: Synapse
messages: focal adhesion
messages: neuron projection

9755:SELE
gene id: 9755:SELE
uniprot id: A0A2Y9EHJ9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selectin/LECAM family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:LOC102990906
gene id: 9755:LOC102990906
uniprot id: A0A2Y9FQH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYF2 family.
messages: Involved in pre-mRNA splicing.
messages: May be part of a spliceosome complex.
messages: Nucleus

9755:RBM15B
gene id: 9755:RBM15B
uniprot id: A0A2Y9F903
uniprot id: A0A455AUQ4
names: Similarity
messages: Belongs to the RRM Spen family.

9755:PDXK
gene id: 9755:PDXK
uniprot id: A0A2Y9FF41
uniprot id: A0A455BXG4
names: Similarity
messages: Belongs to the pyridoxine kinase family.

9755:GLI2
gene id: 9755:GLI2
uniprot id: A0A2Y9S6C3
uniprot id: A0A2Y9S9A3
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

9755:RIOK1
gene id: 9755:RIOK1
uniprot id: A0A2Y9EFZ2
uniprot id: A0A455ADU2
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

9755:RPA3
gene id: 9755:RPA3
uniprot id: A0A2Y9FIM1
uniprot id: A0A2Y9FKQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 3 family.
messages: Nucleus

9755:VPS33B
gene id: 9755:VPS33B
uniprot id: A0A2Y9ESX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: clathrin-coated vesicle

9755:PTPN21
gene id: 9755:PTPN21
uniprot id: A0A2Y9T7A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

9755:MAPRE1
gene id: 9755:MAPRE1
uniprot id: A0A2Y9T3N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

9755:LOC102995707
gene id: 9755:LOC102995707
uniprot id: A0A2Y9FHY3
names: Similarity
messages: Belongs to the SMIM12 family.

9755:INA
gene id: 9755:INA
uniprot id: A0A2Y9FU18
names: Similarity
messages: Belongs to the intermediate filament family.

9755:PANX2
gene id: 9755:PANX2
uniprot id: A0A455BRV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

9755:EIF4E3
gene id: 9755:EIF4E3
uniprot id: A0A2Y9STC6
uniprot id: A0A455ADJ1
uniprot id: A0A455AQS2
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

9755:MCHR2
gene id: 9755:MCHR2
uniprot id: A0A2Y9F2J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9755:ARL11
gene id: 9755:ARL11
uniprot id: A0A455BWX8
uniprot id: A0A455BWY0
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

9755:LOC102986325
gene id: 9755:LOC102986325
uniprot id: A0A2Y9T3C6
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

9755:MRPS18C
gene id: 9755:MRPS18C
uniprot id: A0A2Y9FAN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Mitochondrion

9755:ALDH6A1
gene id: 9755:ALDH6A1
uniprot id: A0A2Y9FG62
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA.

9755:MCL1
gene id: 9755:MCL1
uniprot id: A0A2Y9S808
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Cytoplasm
messages: Membrane
messages: nucleoplasm

9755:LOC114484601
gene id: 9755:LOC114484601
uniprot id: A0A455AP69
names: Similarity
messages: Belongs to the cytochrome P450 family.

9755:LOC102990856
gene id: 9755:LOC102990856
uniprot id: A0A2Y9FCU7
names: Similarity
messages: Belongs to the cytochrome P450 family.

9755:RNF39
gene id: 9755:RNF39
uniprot id: A0A2Y9SHD6
names: Subcellular Location Annotation
messages: Cytoplasm

9755:TACR2
gene id: 9755:TACR2
uniprot id: A0A2Y9FED6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9755:LOC102986575
gene id: 9755:LOC102986575
uniprot id: A0A2Y9F9X9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

9755:LANCL2
gene id: 9755:LANCL2
uniprot id: A0A2Y9RWZ8
names: Similarity
messages: Belongs to the LanC-like protein family.

9755:LOC112066265
gene id: 9755:LOC112066265
uniprot id: A0A455BNM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB2 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9755:ATP6V1E1
gene id: 9755:ATP6V1E1
uniprot id: A0A455BRZ3
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

9755:SDF4
gene id: 9755:SDF4
uniprot id: A0A2Y9SY80
uniprot id: A0A455BIQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREC family.
messages: Golgi apparatus lumen

9755:NR5A1
gene id: 9755:NR5A1
uniprot id: A0A2Y9F6N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR5 subfamily.
messages: Nucleus

9755:TOR1AIP1
gene id: 9755:TOR1AIP1
uniprot id: A0A2Y9ELU7
uniprot id: A0A2Y9EMM3
uniprot id: A0A2Y9EMU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOR1AIP family.
messages: Membrane

9755:TRMT2B
gene id: 9755:TRMT2B
uniprot id: A0A455AN23
uniprot id: A0A455APX1
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:MID1IP1
gene id: 9755:MID1IP1
uniprot id: A0A2Y9F2I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

9755:DNAH6
gene id: 9755:DNAH6
uniprot id: A0A2Y9T7X0
names: Similarity
messages: Belongs to the dynein heavy chain family.

9755:EFNB2
gene id: 9755:EFNB2
uniprot id: A0A2Y9SKS2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:ITIH1
gene id: 9755:ITIH1
uniprot id: A0A2Y9FA65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

9755:PPARA
gene id: 9755:PPARA
uniprot id: A0A455BCN7
uniprot id: A0A455BF18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.
messages: Nucleus

9755:PAIP2B
gene id: 9755:PAIP2B
uniprot id: A0A2Y9FRA9
names: Similarity
messages: Belongs to the PAIP2 family.

9755:TSPAN17
gene id: 9755:TSPAN17
uniprot id: A0A2Y9EI18
uniprot id: A0A455BX51
uniprot id: A0A455BX56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9755:DIO3
gene id: 9755:DIO3
uniprot id: A0A2Y9TAE3
names: Function
names: Similarity
messages: Belongs to the iodothyronine deiodinase family.
messages: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).

9755:LOC102983767
gene id: 9755:LOC102983767
uniprot id: A0A455C351
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9755:TDP2
gene id: 9755:TDP2
uniprot id: A0A2Y9F6W7
names: Subcellular Location Annotation
messages: PML body

9755:CACNA2D4
gene id: 9755:CACNA2D4
uniprot id: A0A2Y9T7G2
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

9755:C9H9orf131
gene id: 9755:C9H9orf131
uniprot id: A0A455BLM8
names: Similarity
messages: Belongs to the SPATA31 family.

9755:GPRC6A
gene id: 9755:GPRC6A
uniprot id: A0A2Y9FIE6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9755:SPATA31F1
gene id: 9755:SPATA31F1
uniprot id: A0A2Y9EF94
names: Similarity
messages: Belongs to the SPATA31 family.

9755:ATG16L2
gene id: 9755:ATG16L2
uniprot id: A0A2Y9EX26
uniprot id: A0A455C5E9
uniprot id: A0A455C5F3
uniprot id: A0A455C5P6
uniprot id: A0A455C5Q0
uniprot id: A0A455C6F2
uniprot id: A0A455C6F8
uniprot id: A0A455C8W5
uniprot id: A0A455C8W7
uniprot id: A0A455CBL9
names: Similarity
messages: Belongs to the WD repeat ATG16 family.

9755:GLRX
gene id: 9755:GLRX
uniprot id: A0A2Y9SHK9
names: Function
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

9755:CRX
gene id: 9755:CRX
uniprot id: A0A2Y9FK04
names: Subcellular Location Annotation
messages: Nucleus

9755:DNAAF2
gene id: 9755:DNAAF2
uniprot id: A0A2Y9ENL1
uniprot id: A0A2Y9EPE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PIH1 family. Kintoun subfamily.
messages: Cytoplasm
messages: Interacts with CFAP300. Interacts with DNAI2 and HSPA1A. Interacts with DYX1C1. Interacts with PIH1D3.
messages: Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment.

9755:LOC102974505
gene id: 9755:LOC102974505
uniprot id: A0A455AB86
names: Subcellular Location Annotation
messages: Nucleus

9755:CISD2
gene id: 9755:CISD2
uniprot id: A0A2Y9FEL0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CISD protein family. CISD2 subfamily.
messages: Binds 1 [2Fe-2S] cluster.
messages: Endoplasmic reticulum membrane
messages: Homodimer.
messages: Mitochondrion outer membrane
messages: Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy.

9755:CDC14B
gene id: 9755:CDC14B
uniprot id: A0A2Y9FCC1
uniprot id: A0A2Y9FCE5
uniprot id: A0A2Y9FCE8
uniprot id: A0A2Y9FCK4
uniprot id: A0A2Y9TEC6
uniprot id: A0A455BM08
uniprot id: A0A455BMH9
uniprot id: A0A455C1V5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

9755:GPKOW
gene id: 9755:GPKOW
uniprot id: A0A2Y9FED5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MOS2 family.
messages: Nucleus
messages: RNA-binding protein involved in pre-mRNA splicing.

9755:ADRB3
gene id: 9755:ADRB3
uniprot id: A0A455ALJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.
messages: Cell membrane
messages: Interacts with ARRDC3.
messages: Membrane

9755:TMEM123
gene id: 9755:TMEM123
uniprot id: A0A2Y9FHH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD164 family.
messages: Membrane

9755:SLC35E3
gene id: 9755:SLC35E3
uniprot id: A0A2Y9FWZ3
names: Subcellular Location Annotation
messages: Membrane

9755:PARP14
gene id: 9755:PARP14
uniprot id: A0A2Y9F835
names: Similarity
messages: Belongs to the ARTD/PARP family.

9755:GIMD1
gene id: 9755:GIMD1
uniprot id: A0A2Y9S958
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

9755:NHERF2
gene id: 9755:NHERF2
uniprot id: A0A2Y9ECY5
uniprot id: A0A2Y9SK67
uniprot id: A0A2Y9SNK9
names: Function
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Endomembrane system
messages: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.

9755:LOC102986136
gene id: 9755:LOC102986136
uniprot id: A0A2Y9TDG8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:MTM1
gene id: 9755:MTM1
uniprot id: A0A2Y9FS99
uniprot id: A0A455ANJ7
uniprot id: A0A455ANT3
uniprot id: A0A455AQ84
uniprot id: A0A455AQN5
uniprot id: A0A455B2D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

9755:LOC102992213
gene id: 9755:LOC102992213
uniprot id: A0A2Y9S466
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:TNRC6B
gene id: 9755:TNRC6B
uniprot id: A0A455BBS2
uniprot id: A0A455BCF2
uniprot id: A0A455BCJ3
uniprot id: A0A455BRD4
names: Similarity
messages: Belongs to the GW182 family.

9755:WNT16
gene id: 9755:WNT16
uniprot id: A0A2Y9F696
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9755:RIMBP2
gene id: 9755:RIMBP2
uniprot id: A0A455AJF6
names: Similarity
messages: Belongs to the RIMBP family.

9755:F11R
gene id: 9755:F11R
uniprot id: A0A2Y9F1T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily.
messages: Cell membrane
messages: Membrane
messages: tight junction

9755:DCLK2
gene id: 9755:DCLK2
uniprot id: A0A2Y9F321
uniprot id: A0A2Y9F3V0
uniprot id: A0A2Y9T0N3
uniprot id: A0A455BF04
uniprot id: A0A455BFI9
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

9755:LDLRAD2
gene id: 9755:LDLRAD2
uniprot id: A0A455B446
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:TFB1M
gene id: 9755:TFB1M
uniprot id: A0A455BPD4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

9755:SF1
gene id: 9755:SF1
uniprot id: A0A2Y9TDB9
uniprot id: A0A2Y9TF83
uniprot id: A0A2Y9TF89
uniprot id: A0A2Y9THA2
uniprot id: A0A2Y9THA6
uniprot id: A0A2Y9TJ16
uniprot id: A0A2Y9TJ18
uniprot id: A0A2Y9TJP1
uniprot id: A0A455C669
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBP/SF1 family.
messages: Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.
messages: Nucleus

9755:NRP2
gene id: 9755:NRP2
uniprot id: A0A2Y9SNV4
uniprot id: A0A2Y9SPW5
uniprot id: A0A2Y9SSB7
uniprot id: A0A2Y9SX51
names: Caution
names: Similarity
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:PPM1L
gene id: 9755:PPM1L
uniprot id: A0A2Y9SWC2
uniprot id: A0A455BCL4
names: Similarity
messages: Belongs to the PP2C family.

9755:PPP3R1
gene id: 9755:PPP3R1
uniprot id: A0A2Y9TJR4
names: Similarity
messages: Belongs to the calcineurin regulatory subunit family.

9755:LIG3
gene id: 9755:LIG3
uniprot id: A0A2Y9ENF6
uniprot id: A0A2Y9EP84
uniprot id: A0A455CAY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

9755:NCL
gene id: 9755:NCL
uniprot id: A0A2Y9SX22
names: Function
names: Subcellular Location Annotation
messages: Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats.
messages: nucleolus

9755:ATF7IP
gene id: 9755:ATF7IP
uniprot id: A0A2Y9T5E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCAF family.
messages: Nucleus

9755:RAB27B
gene id: 9755:RAB27B
uniprot id: A0A2Y9FJP7
uniprot id: A0A2Y9FL18
uniprot id: A0A2Y9TAU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

9755:GSC
gene id: 9755:GSC
uniprot id: A0A2Y9TAV7
names: Subcellular Location Annotation
messages: Nucleus

9755:NKD1
gene id: 9755:NKD1
uniprot id: A0A2Y9STY1
uniprot id: A0A455APN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKD family.
messages: Cell autonomous antagonist of the canonical Wnt signaling pathway.
messages: Cell membrane
messages: Cytoplasm

9755:FN1
gene id: 9755:FN1
uniprot id: A0A2Y9EED2
uniprot id: A0A2Y9EF02
uniprot id: A0A2Y9EFF6
uniprot id: A0A2Y9EFG1
uniprot id: A0A2Y9EFM7
uniprot id: A0A2Y9EFN3
uniprot id: A0A2Y9EG48
uniprot id: A0A455ANC8
names: Function
messages: Secreted by contracting muscle, induces liver autophagy, a degradative pathway for nutrient mobilization and damage removal, and systemic insulin sensitization via hepatic ITGA5:ITGB1 integrin receptor signaling.

9755:PKD2L2
gene id: 9755:PKD2L2
uniprot id: A0A455BZR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Membrane

9755:DGCR2
gene id: 9755:DGCR2
uniprot id: A0A455AKE5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:LOC102994965
gene id: 9755:LOC102994965
uniprot id: A0A2Y9SSM8
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

9755:ITIH4
gene id: 9755:ITIH4
uniprot id: A0A455AEN1
uniprot id: A0A455AGE3
uniprot id: A0A455AH20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

9755:MCM10
gene id: 9755:MCM10
uniprot id: A0A2Y9S0M6
uniprot id: A0A2Y9S0N4
uniprot id: A0A2Y9S476
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM10 family.
messages: Nucleus

9755:ZNF326
gene id: 9755:ZNF326
uniprot id: A0A2Y9F2B9
uniprot id: A0A2Y9F376
uniprot id: A0A2Y9SB05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AKAP95 family.
messages: Nucleus matrix

9755:DPPA4
gene id: 9755:DPPA4
uniprot id: A0A2Y9FBM6
names: Subcellular Location Annotation
messages: Nucleus

9755:SH3RF1
gene id: 9755:SH3RF1
uniprot id: A0A2Y9TCJ3
names: Similarity
messages: Belongs to the SH3RF family.

9755:CLK4
gene id: 9755:CLK4
uniprot id: A0A2Y9F2C7
names: Similarity
messages: Belongs to the protein kinase superfamily.

9755:MELTF
gene id: 9755:MELTF
uniprot id: A0A2Y9F4Z7
uniprot id: A0A2Y9SUN4
names: Similarity
messages: Belongs to the transferrin family.

9755:TUBGCP4
gene id: 9755:TUBGCP4
uniprot id: A0A2Y9TKF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

9755:LOC114487443
gene id: 9755:LOC114487443
uniprot id: A0A455BVZ2
names: Similarity
messages: Belongs to the SURF6 family.

9755:RPL17
gene id: 9755:RPL17
uniprot id: A0A2Y9FIE8
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

9755:PLA2G12A
gene id: 9755:PLA2G12A
uniprot id: A0A2Y9S9T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Secreted

9755:PPP1R15B
gene id: 9755:PPP1R15B
uniprot id: A0A2Y9FUJ8
names: Similarity
messages: Belongs to the PPP1R15 family.

9755:SLC13A1
gene id: 9755:SLC13A1
uniprot id: A0A2Y9FX34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

9755:UBAP2L
gene id: 9755:UBAP2L
uniprot id: A0A2Y9S6W2
uniprot id: A0A455B6N1
uniprot id: A0A455B6N6
uniprot id: A0A455B6N9
uniprot id: A0A455B721
uniprot id: A0A455B726
uniprot id: A0A455B730
uniprot id: A0A455B7H8
uniprot id: A0A455B7I3
uniprot id: A0A455B7I8
uniprot id: A0A455B9F0
uniprot id: A0A455B9F5
uniprot id: A0A455B9G0
uniprot id: A0A455BL20
uniprot id: A0A455BL25
uniprot id: A0A455BL30
uniprot id: A0A455BL37
names: Subcellular Location Annotation
messages: Cytoplasm

9755:LOC102982825
gene id: 9755:LOC102982825
uniprot id: A0A2Y9SYI1
uniprot id: A0A455BF22
uniprot id: A0A455BF27
uniprot id: A0A455BF32
uniprot id: A0A455BF47
uniprot id: A0A455BF50
uniprot id: A0A455BHI8
uniprot id: A0A455BHJ5
uniprot id: A0A455BU57
uniprot id: A0A455BU62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNIP family.
messages: Lysosome membrane
messages: Membrane

9755:INTS8
gene id: 9755:INTS8
uniprot id: A0A2Y9RZ95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 8 family.
messages: Nucleus

9755:STX10
gene id: 9755:STX10
uniprot id: A0A2Y9EK60
uniprot id: A0A455C5H1
names: Subcellular Location Annotation
messages: Golgi apparatus membrane

9755:ENTPD5
gene id: 9755:ENTPD5
uniprot id: A0A2Y9FE80
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

9755:SHKBP1
gene id: 9755:SHKBP1
uniprot id: A0A2Y9FRH5
names: Similarity
messages: Belongs to the KCTD3 family.

9755:DIPK1A
gene id: 9755:DIPK1A
uniprot id: A0A455B824
uniprot id: A0A455B8F9
names: Similarity
messages: Belongs to the DIPK family.

9755:SPTSSB
gene id: 9755:SPTSSB
uniprot id: A0A2Y9F331
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:SLCO1C1
gene id: 9755:SLCO1C1
uniprot id: A0A2Y9FPD9
uniprot id: A0A2Y9FPI9
uniprot id: A0A2Y9FPT1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:B3GALNT1
gene id: 9755:B3GALNT1
uniprot id: A0A2Y9SRT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9755:CPNE6
gene id: 9755:CPNE6
uniprot id: A0A2Y9FTA1
names: Similarity
messages: Belongs to the copine family.

9755:PCBD1
gene id: 9755:PCBD1
uniprot id: A0A2Y9TC55
uniprot id: A0A2Y9THQ9
uniprot id: A0A455AL91
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

9755:DYNC1LI2
gene id: 9755:DYNC1LI2
uniprot id: A0A2Y9SQQ0
uniprot id: A0A2Y9ST34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

9755:STK17B
gene id: 9755:STK17B
uniprot id: A0A2Y9F6S2
names: Similarity
messages: Belongs to the protein kinase superfamily.

9755:FAM166A
gene id: 9755:FAM166A
uniprot id: A0A2Y9EK69
names: Similarity
messages: Belongs to the CIMIP2 family.

9755:CMBL
gene id: 9755:CMBL
uniprot id: A0A2Y9EPY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dienelactone hydrolase family.
messages: cytosol

9755:F9
gene id: 9755:F9
uniprot id: A0A2Y9EF35
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9755:LOC102993851
gene id: 9755:LOC102993851
uniprot id: A0A2Y9ENV1
uniprot id: A0A2Y9THD1
names: Subcellular Location Annotation
messages: Membrane

9755:LRP2
gene id: 9755:LRP2
uniprot id: A0A2Y9EXJ2
names: Caution
names: Similarity
messages: Belongs to the LDLR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:TRHR
gene id: 9755:TRHR
uniprot id: A0A2Y9F9D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

9755:ACVRL1
gene id: 9755:ACVRL1
uniprot id: A0A2Y9SJY3
uniprot id: A0A2Y9SMQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

9755:ELK4
gene id: 9755:ELK4
uniprot id: A0A2Y9TK59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9755:DPP3
gene id: 9755:DPP3
uniprot id: A0A455C747
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M49 family.
messages: Binds 1 zinc ion per subunit.

9755:SMIM12
gene id: 9755:SMIM12
uniprot id: A0A2Y9FHY3
uniprot id: A0A455B2T9
names: Similarity
messages: Belongs to the SMIM12 family.

9755:KCNA5
gene id: 9755:KCNA5
uniprot id: A0A2Y9T5V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.5/KCNA5 sub-subfamily.
messages: Cell membrane
messages: Membrane

9755:SPRN
gene id: 9755:SPRN
uniprot id: A0A2Y9SG11
names: Function
names: Similarity
messages: Belongs to the SPRN family.
messages: Prion-like protein that has PrP(C)-like neuroprotective activity. May act as a modulator for the biological actions of normal and abnormal PrP.

9755:TSEN54
gene id: 9755:TSEN54
uniprot id: A0A2Y9TDN4
names: Similarity
messages: Belongs to the SEN54 family.

9755:TMEM126B
gene id: 9755:TMEM126B
uniprot id: A0A2Y9FGE9
uniprot id: A0A455CBS8
names: Subcellular Location Annotation
messages: Membrane

9755:PRKCZ
gene id: 9755:PRKCZ
uniprot id: A0A2Y9SZJ7
uniprot id: A0A455B4P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

9755:BOP1
gene id: 9755:BOP1
uniprot id: A0A2Y9SBU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat BOP1/ERB1 family.
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

9755:HSPA2
gene id: 9755:HSPA2
uniprot id: A0A2Y9EID0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

9755:LOC102977724
gene id: 9755:LOC102977724
uniprot id: A0A2Y9FQT6
names: Function
names: Subcellular Location Annotation
messages: May function as a transcription factor.
messages: Nucleus

9755:PIM1
gene id: 9755:PIM1
uniprot id: A0A2Y9F4G5
uniprot id: A0A2Y9SKC6
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

9755:KCNK17
gene id: 9755:KCNK17
uniprot id: A0A2Y9FW10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

9755:SPAST
gene id: 9755:SPAST
uniprot id: A0A2Y9SDQ6
uniprot id: A0A455BUP3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. It is critical for the biogenesis and maintenance of complex microtubule arrays in axons, spindles and cilia. SPAST is involved in abscission step of cytokinesis and nuclear envelope reassembly during anaphase in cooperation with the ESCRT-III complex. Recruited at the midbody, probably by IST1, and participates in membrane fission during abscission together with the ESCRT-III complex. Recruited to the nuclear membrane by IST1 and mediates microtubule severing, promoting nuclear envelope sealing and mitotic spindle disassembly during late anaphase. Required for membrane traffic from the endoplasmic reticulum (ER) to the Golgi and endosome recycling. Recruited by IST1 to endosomes and regulates early endosomal tubulation and recycling by mediating microtubule severing. Probably plays a role in axon growth and the formation of axonal branches.
messages: Allosteric enzyme with a cooperative mechanism; at least two neighbor subunits influence each other strongly in spastin hexamers. Microtubule binding promotes cooperative interactions among spastin subunits.
messages: Belongs to the AAA ATPase family. Spastin subfamily.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Homohexamer. Mostly monomeric, but assembles into hexameric structure for short periods of time. Oligomerization seems to be a prerequisite for catalytic activity. Binding to ATP in a cleft between two adjacent subunits stabilizes the homohexameric form. Binds to microtubules at least in part via the alpha-tubulin and beta-tubulin tails. The hexamer adopts a ring conformation through which microtubules pass prior to being severed. Does not interact strongly with tubulin heterodimers. Interacts (via MIT domain) with CHMP1B; the interaction is direct. Interacts with SSNA1. Interacts with ATL1. Interacts with RTN1. Interacts with ZFYVE27. Interacts with REEP1. Interacts (via MIT domain) with IST1.
messages: Membrane
messages: Midbody
messages: Nucleus
messages: axon
messages: centrosome
messages: cytoskeleton
messages: perinuclear region
messages: spindle

9755:CDKN2AIP
gene id: 9755:CDKN2AIP
uniprot id: A0A2Y9S3H6
uniprot id: A0A2Y9S740
uniprot id: A0A2Y9SA06
uniprot id: A0A2Y9SBF4
names: Similarity
messages: Belongs to the CARF family.

9755:RPS6KA6
gene id: 9755:RPS6KA6
uniprot id: A0A2Y9T4L7
uniprot id: A0A2Y9T6P5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

9755:FAM124A
gene id: 9755:FAM124A
uniprot id: A0A2Y9SWS6
names: Similarity
messages: Belongs to the FAM124 family.

9755:CAB39L
gene id: 9755:CAB39L
uniprot id: A0A2Y9EMV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

9755:NFE2L3
gene id: 9755:NFE2L3
uniprot id: A0A2Y9SYN1
names: Similarity
messages: Belongs to the bZIP family. CNC subfamily.

9755:CCM2L
gene id: 9755:CCM2L
uniprot id: A0A2Y9T856
names: Similarity
messages: Belongs to the CCM2 family.

9755:LOC102984680
gene id: 9755:LOC102984680
uniprot id: A0A455B4K0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

9755:UCMA
gene id: 9755:UCMA
uniprot id: A0A2Y9FL65
uniprot id: A0A455BU17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UCMA family.
messages: May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface.
messages: extracellular matrix

9755:LOC102987467
gene id: 9755:LOC102987467
uniprot id: A0A2Y9EL34
names: Similarity
messages: Belongs to the MORF4 family-associated protein family.

9755:SNED1
gene id: 9755:SNED1
uniprot id: A0A2Y9SS86
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:LOC102974359
gene id: 9755:LOC102974359
uniprot id: A0A2Y9EHF3
names: Similarity
messages: Belongs to the CD36 family.

9755:STAT6
gene id: 9755:STAT6
uniprot id: A0A2Y9EJ89
uniprot id: A0A2Y9EL63
uniprot id: A0A455BT40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

9755:MAPK1IP1L
gene id: 9755:MAPK1IP1L
uniprot id: A0A2Y9F6P2
names: Similarity
messages: Belongs to the MISS family.

9755:ALMS1
gene id: 9755:ALMS1
uniprot id: A0A455BUB4
uniprot id: A0A455BUB5
uniprot id: A0A455BXS6
names: Subcellular Location Annotation
messages: centrosome

9755:SLC30A1
gene id: 9755:SLC30A1
uniprot id: A0A2Y9EHW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

9755:TSPAN4
gene id: 9755:TSPAN4
uniprot id: A0A2Y9EUT1
uniprot id: A0A2Y9TER0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9755:PPP3CB
gene id: 9755:PPP3CB
uniprot id: A0A2Y9EXY3
uniprot id: A0A2Y9TC65
uniprot id: A0A2Y9TE28
uniprot id: A0A455ALM4
uniprot id: A0A455ALX2
uniprot id: A0A455ANF0
uniprot id: A0A455ANP8
uniprot id: A0A455B0E0
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

9755:TIMM22
gene id: 9755:TIMM22
uniprot id: A0A2Y9FI23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM22 complex.
messages: Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.
messages: Membrane
messages: Mitochondrion inner membrane

9755:RANBP17
gene id: 9755:RANBP17
uniprot id: A0A2Y9RZ57
uniprot id: A0A2Y9S6Z0
uniprot id: A0A455BVX6
uniprot id: A0A455BVX7
uniprot id: A0A455BVY1
uniprot id: A0A455BVY8
uniprot id: A0A455BWL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus

9755:LOC102978767
gene id: 9755:LOC102978767
uniprot id: A0A2Y9EW64
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

9755:NOTCH3
gene id: 9755:NOTCH3
uniprot id: A0A2Y9TGL5
uniprot id: A0A455C007
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

9755:MAT2B
gene id: 9755:MAT2B
uniprot id: A0A2Y9FF07
uniprot id: A0A2Y9FF69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family. MAT2B subfamily.
messages: Heterotrimer; composed of a catalytic MAT2A homodimer that binds one regulatory MAT2B chain. Heterohexamer; composed of a central, catalytic MAT2A homotetramer flanked on either side by a regulatory MAT2B chain. NADP binding increases the affinity for MAT2A.
messages: Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.

9755:COPS7B
gene id: 9755:COPS7B
uniprot id: A0A2Y9FJP3
uniprot id: A0A2Y9FJR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
messages: Cytoplasm
messages: Nucleus

9755:EFNA5
gene id: 9755:EFNA5
uniprot id: A0A2Y9EQ37
uniprot id: A0A2Y9EQ64
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:DHX15
gene id: 9755:DHX15
uniprot id: A0A2Y9FKD6
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.

9755:ADGRL2
gene id: 9755:ADGRL2
uniprot id: A0A2Y9EPC6
uniprot id: A0A2Y9EPV4
uniprot id: A0A2Y9EQQ5
names: Subcellular Location Annotation
messages: Membrane

9755:LOC102989673
gene id: 9755:LOC102989673
uniprot id: A0A2Y9S791
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:HTR5A
gene id: 9755:HTR5A
uniprot id: A0A2Y9FK45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9755:GPR87
gene id: 9755:GPR87
uniprot id: A0A2Y9FBV7
uniprot id: A0A2Y9FCC3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9755:LOC114484299
gene id: 9755:LOC114484299
uniprot id: A0A455AI16
names: Similarity
messages: Belongs to the DCP1 family.

9755:LEPR
gene id: 9755:LEPR
uniprot id: A0A2Y9FFN8
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane

9755:DCLRE1B
gene id: 9755:DCLRE1B
uniprot id: A0A2Y9ETW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

9755:JAKMIP1
gene id: 9755:JAKMIP1
uniprot id: A0A2Y9F568
uniprot id: A0A2Y9SFU3
names: Similarity
messages: Belongs to the JAKMIP family.

9755:SIAH1
gene id: 9755:SIAH1
uniprot id: A0A2Y9EPD2
uniprot id: A0A2Y9SSZ5
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

9755:CNFN
gene id: 9755:CNFN
uniprot id: A0A2Y9EGG8
uniprot id: A0A455ADB8
names: Similarity
messages: Belongs to the cornifelin family.

9755:SNTG1
gene id: 9755:SNTG1
uniprot id: A0A2Y9SW13
uniprot id: A0A2Y9T1V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: cytoskeleton

9755:AQP3
gene id: 9755:AQP3
uniprot id: A0A2Y9EYB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

9755:NSDHL
gene id: 9755:NSDHL
uniprot id: A0A2Y9FEU1
uniprot id: A0A455AQK7
names: Similarity
messages: Belongs to the 3-beta-HSD family.

9755:PDGFRL
gene id: 9755:PDGFRL
uniprot id: A0A2Y9TAH5
uniprot id: A0A455AMA3
names: Subunit
messages: Forms a complex composed of PDGFRL, TNK2 and GRB2.

9755:LNPK
gene id: 9755:LNPK
uniprot id: A0A2Y9SNW6
uniprot id: A0A2Y9SQP2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Homodimer; homodimerization requires the C4-type zinc finger motif and decreases during mitosis in a phosphorylation-dependent manner.
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

9755:SLC34A1
gene id: 9755:SLC34A1
uniprot id: A0A2Y9EIZ3
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Membrane

9755:LSM5
gene id: 9755:LSM5
uniprot id: A0A455B9S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.

9755:LOC102974723
gene id: 9755:LOC102974723
uniprot id: A0A2Y9SWN2
names: Subcellular Location Annotation
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9755:LOC112065979
gene id: 9755:LOC112065979
uniprot id: A0A2Y9SXX3
names: Subcellular Location Annotation
messages: Nucleus

9755:STON2
gene id: 9755:STON2
uniprot id: A0A2Y9TDC4
uniprot id: A0A455BST7
uniprot id: A0A455C805
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Stoned B family.
messages: Cytoplasm

9755:LOC114485977
gene id: 9755:LOC114485977
uniprot id: A0A455B4J3
names: Subcellular Location Annotation
messages: Membrane

9755:YWHAB
gene id: 9755:YWHAB
uniprot id: A0A2Y9T7M5
names: Similarity
messages: Belongs to the 14-3-3 family.

9755:DYNC1I2
gene id: 9755:DYNC1I2
uniprot id: A0A2Y9FFS1
uniprot id: A0A455AF55
uniprot id: A0A455AF60
uniprot id: A0A455AF66
uniprot id: A0A455AGH0
uniprot id: A0A455AH46
names: Similarity
messages: Belongs to the dynein intermediate chain family.

9755:ACAD8
gene id: 9755:ACAD8
uniprot id: A0A2Y9EJK7
uniprot id: A0A455C6U3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

9755:LOC102974101
gene id: 9755:LOC102974101
uniprot id: A0A2Y9FMX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the THAP1 family.
messages: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes.
messages: Interacts with PAWR. Component of a THAP1/THAP3-HCFC1-OGT complex that contains, either THAP1 or THAP3, HCFC1 and OGT. Interacts with OGT. Interacts (via the HBM) with HCFC1 (via the Kelch-repeat domain); the interaction recruits HCFC1 to the RRM1 promoter.
messages: nucleoplasm

9755:TIMP1
gene id: 9755:TIMP1
uniprot id: A0A2Y9ELX0
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

9755:UBN2
gene id: 9755:UBN2
uniprot id: A0A2Y9T3L5
uniprot id: A0A2Y9T5M6
uniprot id: A0A455B9X7
uniprot id: A0A455BC06
names: Similarity
messages: Belongs to the ubinuclein family.

9755:PPP2R5A
gene id: 9755:PPP2R5A
uniprot id: A0A2Y9TIQ2
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

9755:TMEM45B
gene id: 9755:TMEM45B
uniprot id: A0A2Y9FFR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

9755:TPD52L1
gene id: 9755:TPD52L1
uniprot id: A0A2Y9F1Z4
uniprot id: A0A455BR22
names: Similarity
messages: Belongs to the TPD52 family.

9755:REEP6
gene id: 9755:REEP6
uniprot id: A0A2Y9FDM8
uniprot id: A0A455C5J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

9755:GABRR1
gene id: 9755:GABRR1
uniprot id: A0A2Y9EK28
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Interacts with SQSTM1.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9755:PGM1
gene id: 9755:PGM1
uniprot id: A0A2Y9FPC7
uniprot id: A0A2Y9FPM0
uniprot id: A0A455BAX1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

9755:GCH1
gene id: 9755:GCH1
uniprot id: A0A2Y9F766
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

9755:AKR1D1
gene id: 9755:AKR1D1
uniprot id: A0A2Y9FAL8
uniprot id: A0A2Y9FB03
names: Similarity
messages: Belongs to the aldo/keto reductase family.

9755:DYNLL1
gene id: 9755:DYNLL1
uniprot id: A0A2Y9FT15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

9755:PPT2
gene id: 9755:PPT2
uniprot id: A0A2Y9FAR5
uniprot id: A0A2Y9FCQ1
uniprot id: A0A455AH63
uniprot id: A0A455AUT3
names: Similarity
messages: Belongs to the palmitoyl-protein thioesterase family.

9755:MICAL3
gene id: 9755:MICAL3
uniprot id: A0A455BCU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Cytoplasm

9755:EMC6
gene id: 9755:EMC6
uniprot id: A0A2Y9FKE7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC6 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:EIF3J
gene id: 9755:EIF3J
uniprot id: A0A2Y9F679
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit J family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. This subunit binds directly within the mRNA entry channel of the 40S ribosome to the aminoacyl (A) site. It may regulate the interaction between the 43S PIC and mRNA.
messages: Cytoplasm
messages: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.

9755:AMACR
gene id: 9755:AMACR
uniprot id: A0A2Y9F7P5
uniprot id: A0A455BIJ1
names: Similarity
messages: Belongs to the CoA-transferase III family.

9755:KCNK18
gene id: 9755:KCNK18
uniprot id: A0A2Y9FLV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

9755:B4GALT6
gene id: 9755:B4GALT6
uniprot id: A0A2Y9FU13
uniprot id: A0A2Y9FU75
uniprot id: A0A2Y9FW50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

9755:LOC102977917
gene id: 9755:LOC102977917
uniprot id: A0A2Y9FT48
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:GABRA1
gene id: 9755:GABRA1
uniprot id: A0A2Y9FDX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA1 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9755:HEBP2
gene id: 9755:HEBP2
uniprot id: A0A2Y9SIL1
names: Similarity
messages: Belongs to the HEBP family.

9755:METTL3
gene id: 9755:METTL3
uniprot id: A0A2Y9EN43
uniprot id: A0A455BUD2
names: Similarity
messages: Belongs to the MT-A70-like family.

9755:LOC102993255
gene id: 9755:LOC102993255
uniprot id: A0A2Y9TJI4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:LOC102989916
gene id: 9755:LOC102989916
uniprot id: A0A2Y9EWJ9
names: Subcellular Location Annotation
messages: Secreted

9755:DCTN5
gene id: 9755:DCTN5
uniprot id: A0A2Y9ENH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunits 5/6 family. Dynactin subunit 5 subfamily.
messages: cytoskeleton

9755:STAC3
gene id: 9755:STAC3
uniprot id: A0A2Y9EL68
uniprot id: A0A2Y9SSS7
uniprot id: A0A455BE41
uniprot id: A0A455BGH7
names: Subcellular Location Annotation
messages: sarcolemma

9755:PALMD
gene id: 9755:PALMD
uniprot id: A0A2Y9F1M6
names: Similarity
messages: Belongs to the paralemmin family.

9755:RANBP10
gene id: 9755:RANBP10
uniprot id: A0A455ABI8
names: Similarity
messages: Belongs to the RANBP9/10 family.

9755:ADSS2
gene id: 9755:ADSS2
uniprot id: A0A2Y9FAR8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Mitochondrion
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

9755:UST
gene id: 9755:UST
uniprot id: A0A2Y9SR42
uniprot id: A0A455BMK6
uniprot id: A0A455BN26
uniprot id: A0A455BQN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Golgi apparatus membrane
messages: Membrane

9755:LOC112063623
gene id: 9755:LOC112063623
uniprot id: A0A2Y9SDX9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:ANHX
gene id: 9755:ANHX
uniprot id: A0A2Y9SKN1
names: Subcellular Location Annotation
messages: Nucleus

9755:LOC102984737
gene id: 9755:LOC102984737
uniprot id: A0A2Y9TB30
uniprot id: A0A455C397
names: Subcellular Location Annotation
messages: Membrane

9755:LOC102976245
gene id: 9755:LOC102976245
uniprot id: A0A455AGQ7
names: Similarity
messages: Belongs to the actin family.

9755:SNPH
gene id: 9755:SNPH
uniprot id: A0A455BY80
uniprot id: A0A455BZ46
uniprot id: A0A455C232
names: Subcellular Location Annotation
messages: Membrane

9755:DIPK2B
gene id: 9755:DIPK2B
uniprot id: A0A2Y9S8W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Secreted

9755:CLNS1A
gene id: 9755:CLNS1A
uniprot id: A0A2Y9EQP3
uniprot id: A0A2Y9T910
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pICln (TC 1.A.47) family.
messages: Nucleus

9755:SNX30
gene id: 9755:SNX30
uniprot id: A0A2Y9STQ4
uniprot id: A0A455BL22
names: Similarity
messages: Belongs to the sorting nexin family.

9755:ASF1A
gene id: 9755:ASF1A
uniprot id: A0A2Y9SLF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

9755:P2RX6
gene id: 9755:P2RX6
uniprot id: A0A2Y9SK41
uniprot id: A0A455AHC0
uniprot id: A0A455AHC4
uniprot id: A0A455AHT3
uniprot id: A0A455AJ87
uniprot id: A0A455AJ91
uniprot id: A0A455AJH7
uniprot id: A0A455AVM5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

9755:ALG11
gene id: 9755:ALG11
uniprot id: A0A2Y9ETE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Required for N-linked oligosaccharide assembly.

9755:JMJD1C
gene id: 9755:JMJD1C
uniprot id: A0A2Y9FF67
uniprot id: A0A2Y9FFA0
uniprot id: A0A2Y9RY75
uniprot id: A0A2Y9S1Y1
uniprot id: A0A2Y9S5M2
uniprot id: A0A455AMG5
uniprot id: A0A455AP61
uniprot id: A0A455APG8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM2 histone demethylase family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code.
messages: Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors.
messages: Nucleus
messages: The JmjC domain and the C6-type zinc-finger are required for the demethylation activity.

9755:KCNB1
gene id: 9755:KCNB1
uniprot id: A0A2Y9EDU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.1/KCNB1 sub-subfamily.
messages: Lateral cell membrane
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: axon
messages: dendrite
messages: sarcolemma
messages: synaptosome

9755:SCRIB
gene id: 9755:SCRIB
uniprot id: A0A455C4I5
uniprot id: A0A455C4J0
uniprot id: A0A455C5L9
uniprot id: A0A455C8I9
uniprot id: A0A455CBF4
names: Similarity
messages: Belongs to the LAP (LRR and PDZ) protein family.

9755:LOC102979558
gene id: 9755:LOC102979558
uniprot id: A0A2Y9EJN3
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

9755:KLC1
gene id: 9755:KLC1
uniprot id: A0A2Y9TD94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

9755:ILVBL
gene id: 9755:ILVBL
uniprot id: A0A2Y9EH23
uniprot id: A0A455CAH2
names: Similarity
messages: Belongs to the TPP enzyme family.

9755:ALOX5AP
gene id: 9755:ALOX5AP
uniprot id: A0A2Y9EV34
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:LOC114484194
gene id: 9755:LOC114484194
uniprot id: A0A455AEE7
names: Similarity
messages: Belongs to the histone H3 family.

9755:VPS33A
gene id: 9755:VPS33A
uniprot id: A0A2Y9FTL2
uniprot id: A0A455AJR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: clathrin-coated vesicle

9755:ST7L
gene id: 9755:ST7L
uniprot id: A0A2Y9F374
uniprot id: A0A2Y9F3C4
uniprot id: A0A2Y9F3H1
uniprot id: A0A2Y9F4A1
uniprot id: A0A2Y9F519
uniprot id: A0A455B771
uniprot id: A0A455B825
uniprot id: A0A455B830
uniprot id: A0A455BA03
uniprot id: A0A455BLN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ST7 family.
messages: Membrane

9755:ISCA1
gene id: 9755:ISCA1
uniprot id: A0A2Y9FF71
uniprot id: A0A2Y9FH22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HesB/IscA family.
messages: Mitochondrion

9755:WASF3
gene id: 9755:WASF3
uniprot id: A0A2Y9SSY5
uniprot id: A0A455C9E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

9755:TMPRSS9
gene id: 9755:TMPRSS9
uniprot id: A0A455CBN0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:SLC7A11
gene id: 9755:SLC7A11
uniprot id: A0A2Y9FTB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Cell membrane
messages: Membrane

9755:ZDHHC6
gene id: 9755:ZDHHC6
uniprot id: A0A2Y9FED2
uniprot id: A0A2Y9FG98
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9755:APPL1
gene id: 9755:APPL1
uniprot id: A0A2Y9SMQ8
uniprot id: A0A2Y9ST53
uniprot id: A0A2Y9SV36
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: Nucleus
messages: phagosome
messages: ruffle

9755:GLCE
gene id: 9755:GLCE
uniprot id: A0A2Y9FDQ3
names: Similarity
messages: Belongs to the D-glucuronyl C5-epimerase family.

9755:LIPE
gene id: 9755:LIPE
uniprot id: A0A455AB62
uniprot id: A0A455AB64
uniprot id: A0A455AB99
uniprot id: A0A455AMU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 'GDXG' lipolytic enzyme family.
messages: Cell membrane
messages: Lipid droplet
messages: caveola
messages: cytosol

9755:POFUT2
gene id: 9755:POFUT2
uniprot id: A0A2Y9SIU5
names: Similarity
messages: Belongs to the glycosyltransferase 68 family.

9755:IFI44
gene id: 9755:IFI44
uniprot id: A0A2Y9SBB8
names: Similarity
messages: Belongs to the IFI44 family.

9755:TM6SF1
gene id: 9755:TM6SF1
uniprot id: A0A2Y9FUQ6
uniprot id: A0A455BPZ6
uniprot id: A0A455BQ01
uniprot id: A0A455BQ07
uniprot id: A0A455BQ25
uniprot id: A0A455BQ30
uniprot id: A0A455BQQ8
uniprot id: A0A455BQR2
uniprot id: A0A455BTB6
uniprot id: A0A455BTC1
uniprot id: A0A455BTC6
uniprot id: A0A455C541
uniprot id: A0A455C547
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TM6SF family.
messages: Membrane

9755:GATA6
gene id: 9755:GATA6
uniprot id: A0A2Y9SEC9
names: Subcellular Location Annotation
messages: Nucleus

9755:UBALD2
gene id: 9755:UBALD2
uniprot id: A0A2Y9T7C4
names: Similarity
messages: Belongs to the UBALD family.

9755:CAPN9
gene id: 9755:CAPN9
uniprot id: A0A2Y9S981
names: Similarity
messages: Belongs to the peptidase C2 family.

9755:UBR2
gene id: 9755:UBR2
uniprot id: A0A2Y9FDD8
uniprot id: A0A2Y9FDR2
uniprot id: A0A2Y9FDR7
uniprot id: A0A2Y9FFG6
uniprot id: A0A455AEW1
uniprot id: A0A455AFC4
uniprot id: A0A455AST9
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

9755:NELL2
gene id: 9755:NELL2
uniprot id: A0A2Y9SJT1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:NTN4
gene id: 9755:NTN4
uniprot id: A0A2Y9FLY5
uniprot id: A0A2Y9T104
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:MTFR2
gene id: 9755:MTFR2
uniprot id: A0A2Y9F0X8
uniprot id: A0A2Y9SIF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

9755:CDH7
gene id: 9755:CDH7
uniprot id: A0A2Y9EM53
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

9755:MRPL19
gene id: 9755:MRPL19
uniprot id: A0A2Y9FC07
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.

9755:EIF5
gene id: 9755:EIF5
uniprot id: A0A2Y9T7C5
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

9755:ADAM9
gene id: 9755:ADAM9
uniprot id: A0A2Y9TAE2
uniprot id: A0A455ALW7
uniprot id: A0A455ANZ7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:SRRD
gene id: 9755:SRRD
uniprot id: A0A2Y9SDF2
names: Similarity
messages: Belongs to the SRR1 family.

9755:LOC112063964
gene id: 9755:LOC112063964
uniprot id: A0A2Y9SBN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

9755:IDI1
gene id: 9755:IDI1
uniprot id: A0A2Y9T7E5
names: Function
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).

9755:CCNK
gene id: 9755:CCNK
uniprot id: A0A2Y9TAJ1
names: Similarity
messages: Belongs to the cyclin family.

9755:ABLIM2
gene id: 9755:ABLIM2
uniprot id: A0A455BGS3
names: Subcellular Location Annotation
messages: Cytoplasm

9755:ACTL9
gene id: 9755:ACTL9
uniprot id: A0A2Y9EV58
names: Similarity
messages: Belongs to the actin family.

9755:NAAA
gene id: 9755:NAAA
uniprot id: A0A2Y9FGV0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acid ceramidase family.
messages: Heterodimer.
messages: Lysosome

9755:CDSN
gene id: 9755:CDSN
uniprot id: A0A2Y9EQS0
names: Function
names: Subcellular Location Annotation
messages: Important for the epidermal barrier integrity.
messages: Secreted

9755:YWHAE
gene id: 9755:YWHAE
uniprot id: A0A2Y9FI13
uniprot id: A0A455BXM4
names: Similarity
messages: Belongs to the 14-3-3 family.

9755:CDH9
gene id: 9755:CDH9
uniprot id: A0A2Y9F1V0
uniprot id: A0A2Y9SJA2
uniprot id: A0A2Y9SNZ6
uniprot id: A0A2Y9SP09
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

9755:SFRP4
gene id: 9755:SFRP4
uniprot id: A0A2Y9F5D8
uniprot id: A0A455BB52
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:LOC102977192
gene id: 9755:LOC102977192
uniprot id: A0A2Y9S7A8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:RIN2
gene id: 9755:RIN2
uniprot id: A0A2Y9FEE1
uniprot id: A0A455C0J7
uniprot id: A0A455C3H4
names: Similarity
messages: Belongs to the RIN (Ras interaction/interference) family.

9755:FOXI2
gene id: 9755:FOXI2
uniprot id: A0A2Y9SG64
names: Subcellular Location Annotation
messages: Nucleus

9755:SPON1
gene id: 9755:SPON1
uniprot id: A0A2Y9SDU2
names: Subcellular Location Annotation
messages: extracellular matrix

9755:LOC102981654
gene id: 9755:LOC102981654
uniprot id: A0A2Y9SP70
uniprot id: A0A2Y9SVA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA5 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9755:FOXD3
gene id: 9755:FOXD3
uniprot id: A0A2Y9SB72
names: Subcellular Location Annotation
messages: Nucleus

9755:DIP2B
gene id: 9755:DIP2B
uniprot id: A0A2Y9SJ47
uniprot id: A0A2Y9SQH1
uniprot id: A0A455BEF5
uniprot id: A0A455BGV7
uniprot id: A0A455BTH4
names: Similarity
messages: Belongs to the DIP2 family.

9755:PPIL1
gene id: 9755:PPIL1
uniprot id: A0A2Y9EML8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

9755:PGGT1B
gene id: 9755:PGGT1B
uniprot id: A0A2Y9F6M6
uniprot id: A0A455BYU5
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.

9755:LOC102981152
gene id: 9755:LOC102981152
uniprot id: A0A2Y9T6Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

9755:LOC102994476
gene id: 9755:LOC102994476
uniprot id: A0A2Y9EE14
names: Subcellular Location Annotation
messages: Nucleus

9755:LOC102974014
gene id: 9755:LOC102974014
uniprot id: A0A455BS80
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.

9755:GPR52
gene id: 9755:GPR52
uniprot id: A0A2Y9F1R3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9755:PRF1
gene id: 9755:PRF1
uniprot id: A0A2Y9F6I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Secreted

9755:GRB7
gene id: 9755:GRB7
uniprot id: A0A2Y9F282
uniprot id: A0A455C2R5
uniprot id: A0A455C600
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

9755:IPO7
gene id: 9755:IPO7
uniprot id: A0A2Y9SAJ8
names: Subcellular Location Annotation
messages: Cytoplasm

9755:ADAMTS9
gene id: 9755:ADAMTS9
uniprot id: A0A2Y9ST23
uniprot id: A0A455ADE5
uniprot id: A0A455ADS7
uniprot id: A0A455AEX5
uniprot id: A0A455AFT8
uniprot id: A0A455AR32
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9755:SLC19A3
gene id: 9755:SLC19A3
uniprot id: A0A2Y9SNL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

9755:PSMC5
gene id: 9755:PSMC5
uniprot id: A0A2Y9EL16
names: Similarity
messages: Belongs to the AAA ATPase family.

9755:YWHAZ
gene id: 9755:YWHAZ
uniprot id: A0A455C5E3
names: Similarity
messages: Belongs to the 14-3-3 family.

9755:EXOG
gene id: 9755:EXOG
uniprot id: A0A455AS70
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

9755:RARS1
gene id: 9755:RARS1
uniprot id: A0A2Y9EWG1
uniprot id: A0A2Y9EXT8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9755:LOC102994778
gene id: 9755:LOC102994778
uniprot id: A0A455AS23
names: Similarity
messages: Belongs to the SMIM12 family.

9755:MDH2
gene id: 9755:MDH2
uniprot id: A0A2Y9ELI1
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

9755:MSTN
gene id: 9755:MSTN
uniprot id: A0A2Y9ELF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts specifically as a negative regulator of skeletal muscle growth.
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked. Interacts with WFIKKN2, leading to inhibit its activity. Interacts with FSTL3.
messages: Secreted

9755:YARS1
gene id: 9755:YARS1
uniprot id: A0A2Y9FJK5
uniprot id: A0A455B0W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Nucleus

9755:SATB2
gene id: 9755:SATB2
uniprot id: A0A2Y9SSD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

9755:LONP2
gene id: 9755:LONP2
uniprot id: A0A2Y9ENK3
uniprot id: A0A2Y9EPM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta-oxidation through degradation of the self-processed forms of TYSND1.
messages: Belongs to the peptidase S16 family.
messages: Interacts with PEX5. Interacts with TYSND1.
messages: Peroxisome matrix

9755:COG3
gene id: 9755:COG3
uniprot id: A0A2Y9FSM2
uniprot id: A0A2Y9FVI3
uniprot id: A0A2Y9T0R1
uniprot id: A0A455BWQ8
names: Function
names: Similarity
messages: Belongs to the COG3 family.
messages: Involved in ER-Golgi transport.

9755:ERAP1
gene id: 9755:ERAP1
uniprot id: A0A2Y9FEW8
uniprot id: A0A455BYQ1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Membrane

9755:DDOST
gene id: 9755:DDOST
uniprot id: A0A455B4S5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDOST 48 kDa subunit family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).

9755:NT5E
gene id: 9755:NT5E
uniprot id: A0A2Y9EZF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 5'-nucleotidase family.
messages: Membrane

9755:GNPAT
gene id: 9755:GNPAT
uniprot id: A0A2Y9FNM8
uniprot id: A0A2Y9S966
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Peroxisome membrane

9755:ATP2A2
gene id: 9755:ATP2A2
uniprot id: A0A2Y9ELZ3
uniprot id: A0A455AHH4
uniprot id: A0A455AV65
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

9755:CAND1
gene id: 9755:CAND1
uniprot id: A0A2Y9FWI3
names: Similarity
messages: Belongs to the CAND family.

9755:LOC102975242
gene id: 9755:LOC102975242
uniprot id: A0A2Y9T2L4
names: Subcellular Location Annotation
messages: Nucleus

9755:XRCC1
gene id: 9755:XRCC1
uniprot id: A0A455AD90
names: Subcellular Location Annotation
messages: Nucleus

9755:TPST1
gene id: 9755:TPST1
uniprot id: A0A2Y9EPV1
uniprot id: A0A455C3B1
uniprot id: A0A455CB67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein sulfotransferase family.
messages: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
messages: Golgi apparatus membrane

9755:DUSP2
gene id: 9755:DUSP2
uniprot id: A0A2Y9TBX1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

9755:SDE2
gene id: 9755:SDE2
uniprot id: A0A2Y9FPW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDE2 family.
messages: Cytoplasm
messages: Nucleus

9755:SLC30A2
gene id: 9755:SLC30A2
uniprot id: A0A2Y9EY91
uniprot id: A0A455B5X9
uniprot id: A0A455B5Y9
uniprot id: A0A455BHK2
uniprot id: A0A455BHK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

9755:NPPC
gene id: 9755:NPPC
uniprot id: A0A2Y9FLR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

9755:SGO2
gene id: 9755:SGO2
uniprot id: A0A2Y9F1M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

9755:TRAF3
gene id: 9755:TRAF3
uniprot id: A0A2Y9T978
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

9755:SETD6
gene id: 9755:SETD6
uniprot id: A0A455ACY2
uniprot id: A0A455AQ64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily.
messages: Nucleus
messages: Protein-lysine N-methyltransferase.

9755:STMN3
gene id: 9755:STMN3
uniprot id: A0A2Y9T860
names: Similarity
messages: Belongs to the stathmin family.

9755:TSEN15
gene id: 9755:TSEN15
uniprot id: A0A455B5M3
names: Similarity
messages: Belongs to the SEN15 family.

9755:MFSD3
gene id: 9755:MFSD3
uniprot id: A0A2Y9ELZ7
uniprot id: A0A2Y9S3X8
uniprot id: A0A455C634
uniprot id: A0A455C8R3
names: Subcellular Location Annotation
messages: Membrane

9755:GRP
gene id: 9755:GRP
uniprot id: A0A2Y9FSG0
uniprot id: A0A2Y9FUF3
uniprot id: A0A2Y9FVA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bombesin/neuromedin-B/ranatensin family.
messages: Secreted
messages: neuron projection

9755:TRMT11
gene id: 9755:TRMT11
uniprot id: A0A2Y9FUB1
uniprot id: A0A2Y9SLW0
names: Function
names: Subunit
messages: Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.
messages: Interacts with TRMT112.

9755:CHD2
gene id: 9755:CHD2
uniprot id: A0A455BPY5
uniprot id: A0A455BQ04
uniprot id: A0A455BQP2
uniprot id: A0A455BT99
uniprot id: A0A455C531
names: Subcellular Location Annotation
messages: Nucleus

9755:LIPT2
gene id: 9755:LIPT2
uniprot id: A0A2Y9EUB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Mitochondrion

9755:SFTPD
gene id: 9755:SFTPD
uniprot id: A0A2Y9EZJ1
names: Similarity
names: Subunit
messages: Belongs to the SFTPD family.
messages: Oligomeric complex of 4 set of homotrimers.

9755:SLCO2B1
gene id: 9755:SLCO2B1
uniprot id: A0A455C6S0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:LOC112066934
gene id: 9755:LOC112066934
uniprot id: A0A2Y9TA99
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:ST6GALNAC3
gene id: 9755:ST6GALNAC3
uniprot id: A0A2Y9SGC0
uniprot id: A0A455B8R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9755:POU3F4
gene id: 9755:POU3F4
uniprot id: A0A2Y9FCP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

9755:LOC102978514
gene id: 9755:LOC102978514
uniprot id: A0A2Y9SLC4
names: Similarity
messages: Belongs to the cytochrome P450 family.

9755:FXN
gene id: 9755:FXN
uniprot id: A0A2Y9F1U1
uniprot id: A0A2Y9SZ55
names: Similarity
messages: Belongs to the frataxin family.

9755:LOC102991765
gene id: 9755:LOC102991765
uniprot id: A0A2Y9SMB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:INTS7
gene id: 9755:INTS7
uniprot id: A0A2Y9EIJ3
uniprot id: A0A2Y9EJ50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 7 family.
messages: Nucleus

9755:APOC1
gene id: 9755:APOC1
uniprot id: A0A2Y9TD48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apolipoprotein C1 family.
messages: Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor. Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL. Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP). Binds free fatty acids and reduces their intracellular esterification. Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein.
messages: Secreted

9755:CPEB3
gene id: 9755:CPEB3
uniprot id: A0A455AK13
uniprot id: A0A455AKA5
names: Similarity
messages: Belongs to the RRM CPEB family.

9755:DYDC1
gene id: 9755:DYDC1
uniprot id: A0A2Y9EZK3
names: Similarity
messages: Belongs to the dpy-30 family.

9755:MIPEP
gene id: 9755:MIPEP
uniprot id: A0A2Y9SYL0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

9755:SAMD4B
gene id: 9755:SAMD4B
uniprot id: A0A2Y9TDE4
uniprot id: A0A2Y9TFK3
uniprot id: A0A455AB18
uniprot id: A0A455AD71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAUG family.
messages: Cytoplasm

9755:TRIM21
gene id: 9755:TRIM21
uniprot id: A0A2Y9F9K9
names: Subcellular Location Annotation
messages: Cytoplasm

9755:CDK5RAP1
gene id: 9755:CDK5RAP1
uniprot id: A0A2Y9T665
names: Similarity
messages: Belongs to the methylthiotransferase family. MiaB subfamily.

9755:MAP1LC3B
gene id: 9755:MAP1LC3B
uniprot id: A0A2Y9SQ55
names: Similarity
messages: Belongs to the ATG8 family.

9755:ACTR8
gene id: 9755:ACTR8
uniprot id: A0A2Y9FKH5
uniprot id: A0A2Y9FLN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the actin family. ARP8 subfamily.
messages: Chromosome
messages: Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the DBINO domain of INO80. Exists as monomers and dimers, but the dimer is most probably the biologically relevant form required for stable interactions with histones that exploits the twofold symmetry of the nucleosome core.
messages: Nucleus
messages: Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize.
messages: Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.

9755:LOC102991140
gene id: 9755:LOC102991140
uniprot id: A0A2Y9SE32
names: Similarity
messages: Belongs to the cytochrome P450 family.

9755:TAS1R2
gene id: 9755:TAS1R2
uniprot id: A0A455B3R6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9755:SENP5
gene id: 9755:SENP5
uniprot id: A0A2Y9F4Z1
uniprot id: A0A2Y9F530
uniprot id: A0A2Y9F6S8
uniprot id: A0A455BX71
uniprot id: A0A455BX77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C48 family.
messages: nucleolus

9755:RAB3C
gene id: 9755:RAB3C
uniprot id: A0A2Y9EK04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

9755:CDH1
gene id: 9755:CDH1
uniprot id: A0A2Y9EXB8
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

9755:AP5M1
gene id: 9755:AP5M1
uniprot id: A0A2Y9FBZ3
names: Subcellular Location Annotation
names: Subunit
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane
messages: Probably part of the adaptor protein complex 5 (AP-5) a tetramer composed of AP5B1, AP5M1, AP5S1 and AP5Z1.

9755:TGM7
gene id: 9755:TGM7
uniprot id: A0A2Y9TGA6
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.

9755:LOC102980282
gene id: 9755:LOC102980282
uniprot id: A0A2Y9SRX6
names: Similarity
messages: Belongs to the cytochrome c family.

9755:SYT14
gene id: 9755:SYT14
uniprot id: A0A2Y9TK89
uniprot id: A0A455B6P2
uniprot id: A0A455BK71
names: Similarity
messages: Belongs to the synaptotagmin family.

9755:SLC28A3
gene id: 9755:SLC28A3
uniprot id: A0A2Y9TGL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

9755:TMPRSS3
gene id: 9755:TMPRSS3
uniprot id: A0A455BHP6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:LOC102982895
gene id: 9755:LOC102982895
uniprot id: A0A2Y9SAW9
uniprot id: A0A2Y9SIH6
names: Similarity
messages: Belongs to the cytochrome P450 family.

9755:TNS3
gene id: 9755:TNS3
uniprot id: A0A455BDQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTEN phosphatase protein family.
messages: focal adhesion

9755:LOC102993433
gene id: 9755:LOC102993433
uniprot id: A0A2Y9TIN6
names: Subcellular Location Annotation
messages: Membrane

9755:LOC102994440
gene id: 9755:LOC102994440
uniprot id: A0A2Y9FSD4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9755:CCNE1
gene id: 9755:CCNE1
uniprot id: A0A2Y9TI46
names: Similarity
messages: Belongs to the cyclin family.

9755:ACTA2
gene id: 9755:ACTA2
uniprot id: A0A2Y9EGB4
names: Similarity
messages: Belongs to the actin family.

9755:LIN28B
gene id: 9755:LIN28B
uniprot id: A0A2Y9EYC0
names: Similarity
messages: Belongs to the lin-28 family.

9755:PSMD2
gene id: 9755:PSMD2
uniprot id: A0A455BHV4
names: Function
names: Similarity
messages: Belongs to the proteasome subunit S2 family.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

9755:NRXN1
gene id: 9755:NRXN1
uniprot id: A0A2Y9S7B6
uniprot id: A0A2Y9S7C1
uniprot id: A0A2Y9S7C7
uniprot id: A0A2Y9S7D3
uniprot id: A0A2Y9S7D8
uniprot id: A0A2Y9S7N2
uniprot id: A0A2Y9S7N7
uniprot id: A0A2Y9S7P3
uniprot id: A0A2Y9S7S0
uniprot id: A0A2Y9SB23
uniprot id: A0A2Y9SB28
uniprot id: A0A2Y9SB31
uniprot id: A0A2Y9SB39
uniprot id: A0A2Y9SE03
uniprot id: A0A2Y9SE08
uniprot id: A0A2Y9SE12
uniprot id: A0A2Y9SE17
uniprot id: A0A2Y9SE22
uniprot id: A0A2Y9SFG1
uniprot id: A0A2Y9SFG6
uniprot id: A0A2Y9SFH1
uniprot id: A0A2Y9SFH5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Presynaptic cell membrane

9755:H1-1
gene id: 9755:H1-1
uniprot id: A0A2Y9FQK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

9755:B3GNT9
gene id: 9755:B3GNT9
uniprot id: A0A2Y9FKX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9755:LOC102994595
gene id: 9755:LOC102994595
uniprot id: A0A455BPJ1
names: Subcellular Location Annotation
messages: Nucleus

9755:PON2
gene id: 9755:PON2
uniprot id: A0A2Y9F8H6
uniprot id: A0A2Y9F8S8
uniprot id: A0A2Y9F8S9
uniprot id: A0A455BAW6
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the paraoxonase family.
messages: Binds 2 calcium ions per subunit.
messages: Glycosylated.

9755:RAMP1
gene id: 9755:RAMP1
uniprot id: A0A455AQD8
uniprot id: A0A455B437
names: Similarity
messages: Belongs to the RAMP family.

9755:CAPN6
gene id: 9755:CAPN6
uniprot id: A0A2Y9EQU6
names: Caution
names: Similarity
messages: Belongs to the peptidase C2 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:CEBPA
gene id: 9755:CEBPA
uniprot id: A0A2Y9EFL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. C/EBP subfamily.
messages: Nucleus

9755:CR2
gene id: 9755:CR2
uniprot id: A0A2Y9EMQ0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:LOC102996317
gene id: 9755:LOC102996317
uniprot id: A0A2Y9FA28
uniprot id: A0A2Y9FBZ9
names: Similarity
messages: Belongs to the calcitonin family.

9755:NPVF
gene id: 9755:NPVF
uniprot id: A0A2Y9EVU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FARP (FMRFamide related peptide) family.
messages: Secreted

9755:TMBIM4
gene id: 9755:TMBIM4
uniprot id: A0A2Y9FLK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

9755:LOC102974962
gene id: 9755:LOC102974962
uniprot id: A0A2Y9FNK0
names: Similarity
messages: Belongs to the cornifelin family.

9755:ENGASE
gene id: 9755:ENGASE
uniprot id: A0A455CB27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 85 family.
messages: cytosol

9755:FLNA
gene id: 9755:FLNA
uniprot id: A0A2Y9S1N4
names: Similarity
messages: Belongs to the filamin family.

9755:BST1
gene id: 9755:BST1
uniprot id: A0A2Y9FBZ8
uniprot id: A0A2Y9S9N7
uniprot id: A0A2Y9SFT0
uniprot id: A0A2Y9SHE6
names: Similarity
messages: Belongs to the ADP-ribosyl cyclase family.

9755:ERCC5
gene id: 9755:ERCC5
uniprot id: A0A2Y9ESN8
uniprot id: A0A455BXI8
uniprot id: A0A455C167
uniprot id: A0A455C9Y3
uniprot id: A0A455C9Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPG/RAD2 endonuclease family. XPG subfamily.
messages: Nucleus

9755:LOC102985126
gene id: 9755:LOC102985126
uniprot id: A0A2Y9FK60
uniprot id: A0A2Y9SZ11
uniprot id: A0A455BYC3
uniprot id: A0A455BZ86
uniprot id: A0A455C269
uniprot id: A0A455CA42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane

9755:PHACTR4
gene id: 9755:PHACTR4
uniprot id: A0A2Y9EFH6
uniprot id: A0A2Y9EFP9
uniprot id: A0A2Y9SUF4
uniprot id: A0A2Y9SZ02
uniprot id: A0A455B2M7
uniprot id: A0A455BGR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.
messages: Cytoplasm
messages: Regulator of protein phosphatase 1 (PP1) required for neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development. Acts as an activator of PP1. During neural tube closure, localizes to the ventral neural tube and activates PP1, leading to down-regulate cell proliferation within cranial neural tissue and the neural retina. Also acts as a regulator of migration of enteric neural crest cells (ENCCs) by activating PP1, leading to repression of the integrin signaling through the rho/rock pathway.
messages: lamellipodium

9755:PTPRZ1
gene id: 9755:PTPRZ1
uniprot id: A0A2Y9T6E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily.
messages: Membrane

9755:SELP
gene id: 9755:SELP
uniprot id: A0A455B6D4
uniprot id: A0A455B791
uniprot id: A0A455B950
uniprot id: A0A455BKT0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selectin/LECAM family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:MAPK1
gene id: 9755:MAPK1
uniprot id: A0A2Y9SG06
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
messages: caveola
messages: focal adhesion

9755:NANOG
gene id: 9755:NANOG
uniprot id: A0A2Y9T220
uniprot id: A0A2Y9T880
names: Subcellular Location Annotation
messages: Nucleus

9755:C16H11orf54
gene id: 9755:C16H11orf54
uniprot id: A0A2Y9F960
uniprot id: A0A2Y9FAY4
uniprot id: A0A455C6Q5
uniprot id: A0A455C9E9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Exhibits ester hydrolase activity on the substrate p-nitrophenyl acetate.
messages: Monomer.
messages: Nucleus

9755:STK10
gene id: 9755:STK10
uniprot id: A0A2Y9S7D0
uniprot id: A0A455C9F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Cell membrane

9755:PPM1A
gene id: 9755:PPM1A
uniprot id: A0A2Y9S2J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

9755:CRYAA
gene id: 9755:CRYAA
uniprot id: A0A2Y9FRY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.
messages: Nucleus

9755:LGMN
gene id: 9755:LGMN
uniprot id: A0A2Y9FNQ9
names: Similarity
messages: Belongs to the peptidase C13 family.

9755:RAB3IL1
gene id: 9755:RAB3IL1
uniprot id: A0A2Y9FG60
uniprot id: A0A455C7N7
uniprot id: A0A455C7V4
uniprot id: A0A455C9T2
uniprot id: A0A455CC21
names: Similarity
messages: Belongs to the SEC2 family.

9755:CCL20
gene id: 9755:CCL20
uniprot id: A0A2Y9FHF0
uniprot id: A0A2Y9FHM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

9755:GRIN2B
gene id: 9755:GRIN2B
uniprot id: A0A2Y9FNA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

9755:MAS1
gene id: 9755:MAS1
uniprot id: A0A2Y9FXQ8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9755:RNF121
gene id: 9755:RNF121
uniprot id: A0A455C9Q1
names: Subcellular Location Annotation
messages: Membrane

9755:SLC1A2
gene id: 9755:SLC1A2
uniprot id: A0A2Y9FS94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

9755:PGM3
gene id: 9755:PGM3
uniprot id: A0A2Y9F7D5
uniprot id: A0A2Y9F867
uniprot id: A0A2Y9F9C8
uniprot id: A0A2Y9TD25
uniprot id: A0A455BSP0
uniprot id: A0A455BW29
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O-glycosylation.

9755:PTPRF
gene id: 9755:PTPRF
uniprot id: A0A2Y9SS75
uniprot id: A0A2Y9SWY3
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.

9755:UROD
gene id: 9755:UROD
uniprot id: A0A2Y9EX47
names: Similarity
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Homodimer.

9755:SPP2
gene id: 9755:SPP2
uniprot id: A0A2Y9EHP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPP2 family.
messages: Could coordinate an aspect of bone turnover.
messages: Secreted

9755:LOC102985031
gene id: 9755:LOC102985031
uniprot id: A0A2Y9T892
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:PARP8
gene id: 9755:PARP8
uniprot id: A0A2Y9SAC6
names: Similarity
messages: Belongs to the ARTD/PARP family.

9755:CSRNP3
gene id: 9755:CSRNP3
uniprot id: A0A2Y9FQA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

9755:PSMB10
gene id: 9755:PSMB10
uniprot id: A0A2Y9FE14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

9755:LOC102984294
gene id: 9755:LOC102984294
uniprot id: A0A2Y9FSI1
names: Similarity
messages: Belongs to the histone H2B family.

9755:NMNAT2
gene id: 9755:NMNAT2
uniprot id: A0A2Y9THC1
uniprot id: A0A2Y9TKB9
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

9755:SMC3
gene id: 9755:SMC3
uniprot id: A0A2Y9F527
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC3 subfamily.
messages: Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex also plays an important role in spindle pole assembly during mitosis and in chromosomes movement.
messages: Nucleus
messages: centromere

9755:LOC102989468
gene id: 9755:LOC102989468
uniprot id: A0A2Y9SFC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:CTPS1
gene id: 9755:CTPS1
uniprot id: A0A2Y9SR67
uniprot id: A0A2Y9SSK3
names: Caution
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:PAPPA
gene id: 9755:PAPPA
uniprot id: A0A2Y9SZZ2
names: Caution
names: Similarity
messages: Belongs to the peptidase M43B family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:LOC102983630
gene id: 9755:LOC102983630
uniprot id: A0A455C7E6
names: Similarity
messages: Belongs to the PACS family.

9755:ABT1
gene id: 9755:ABT1
uniprot id: A0A2Y9FQQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF2/ABP1 family.
messages: nucleolus

9755:LOC102974264
gene id: 9755:LOC102974264
uniprot id: A0A455BLN7
names: Similarity
messages: Belongs to the NSG family.

9755:SLC25A46
gene id: 9755:SLC25A46
uniprot id: A0A2Y9FA03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion outer membrane

9755:LOC102989093
gene id: 9755:LOC102989093
uniprot id: A0A2Y9SKF9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9755:EIF2B2
gene id: 9755:EIF2B2
uniprot id: A0A2Y9FA58
uniprot id: A0A455BSP2
uniprot id: A0A455BTE2
uniprot id: A0A455C7W5
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

9755:SOAT2
gene id: 9755:SOAT2
uniprot id: A0A2Y9FKR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:RBP1
gene id: 9755:RBP1
uniprot id: A0A2Y9FHU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm

9755:MED13
gene id: 9755:MED13
uniprot id: A0A2Y9T5A0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

9755:HUWE1
gene id: 9755:HUWE1
uniprot id: A0A2Y9FCR5
names: Similarity
messages: Belongs to the UPL family. TOM1/PTR1 subfamily.

9755:SLC6A9
gene id: 9755:SLC6A9
uniprot id: A0A2Y9EZ54
uniprot id: A0A2Y9SR94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A9 subfamily.
messages: Cell membrane
messages: Membrane

9755:LOC112063602
gene id: 9755:LOC112063602
uniprot id: A0A140GN66
names: Similarity
messages: Belongs to the globin family.

9755:HIBADH
gene id: 9755:HIBADH
uniprot id: A0A2Y9FU47
uniprot id: A0A455B9X0
names: Similarity
messages: Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.

9755:LOC102986645
gene id: 9755:LOC102986645
uniprot id: A0A2Y9T6F8
uniprot id: A0A2Y9T9V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

9755:SEC31B
gene id: 9755:SEC31B
uniprot id: A0A455AKN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC31 family.
messages: Endoplasmic reticulum membrane

9755:LOC112067318
gene id: 9755:LOC112067318
uniprot id: A0A455AD99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lambda interferon family.
messages: Secreted

9755:CLRN3
gene id: 9755:CLRN3
uniprot id: A0A2Y9EJG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

9755:MAPK4
gene id: 9755:MAPK4
uniprot id: A0A2Y9TH02
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

9755:ADGRB3
gene id: 9755:ADGRB3
uniprot id: A0A2Y9TEV2
names: Subcellular Location Annotation
messages: Membrane

9755:SCFD2
gene id: 9755:SCFD2
uniprot id: A0A2Y9THE0
uniprot id: A0A455BF91
uniprot id: A0A455BFR6
uniprot id: A0A455BFS1
uniprot id: A0A455BFS6
uniprot id: A0A455BFW8
uniprot id: A0A455BFX2
uniprot id: A0A455BIA9
uniprot id: A0A455BIB3
uniprot id: A0A455BIB9
uniprot id: A0A455BUX9
uniprot id: A0A455BUY4
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

9755:C1H3orf70
gene id: 9755:C1H3orf70
uniprot id: A0A2Y9SNF4
names: Similarity
messages: Belongs to the UPF0524 family.

9755:MYH6
gene id: 9755:MYH6
uniprot id: A0A2Y9TII5
uniprot id: A0A2Y9TKC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: myofibril

9755:TSPAN5
gene id: 9755:TSPAN5
uniprot id: A0A2Y9SW39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9755:POMGNT2
gene id: 9755:POMGNT2
uniprot id: A0A2Y9EPY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 61 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:LOC102988769
gene id: 9755:LOC102988769
uniprot id: A0A2Y9FL34
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flavin monoamine oxidase family.
messages: Mitochondrion outer membrane
messages: Monomer, homo- or heterodimer (containing two subunits of similar size). Each subunit contains a covalently bound flavin. Enzymatically active as monomer.

9755:DCPS
gene id: 9755:DCPS
uniprot id: A0A2Y9FK51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HIT family.
messages: Cytoplasm
messages: Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway.
messages: Homodimer. Associates with components of the exosome multienzyme ribonuclease complex, such as EXOSC3 and EXOSC4. Interacts with NDOR1.
messages: Nucleus

9755:FOXR2
gene id: 9755:FOXR2
uniprot id: A0A2Y9FHP6
names: Subcellular Location Annotation
messages: Nucleus

9755:RNF34
gene id: 9755:RNF34
uniprot id: A0A2Y9FQX7
uniprot id: A0A2Y9FR36
names: Subcellular Location Annotation
messages: Cell membrane

9755:IL24
gene id: 9755:IL24
uniprot id: A0A2Y9ENA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

9755:NOX4
gene id: 9755:NOX4
uniprot id: A0A2Y9T928
uniprot id: A0A2Y9TCL3
names: Subcellular Location Annotation
messages: Membrane

9755:PRR5
gene id: 9755:PRR5
uniprot id: A0A2Y9T4W0
uniprot id: A0A455BCM9
names: Similarity
messages: Belongs to the PROTOR family.

9755:GCNT1
gene id: 9755:GCNT1
uniprot id: A0A2Y9FDU9
uniprot id: A0A2Y9FE18
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

9755:LOC102986303
gene id: 9755:LOC102986303
uniprot id: A0A2Y9EFI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 18 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

9755:MOSPD1
gene id: 9755:MOSPD1
uniprot id: A0A2Y9EGQ7
uniprot id: A0A455AR46
names: Subcellular Location Annotation
messages: Membrane

9755:STX11
gene id: 9755:STX11
uniprot id: A0A2Y9EEK7
names: Similarity
messages: Belongs to the syntaxin family.

9755:LOC102994465
gene id: 9755:LOC102994465
uniprot id: A0A2Y9F6M4
names: Similarity
messages: Belongs to the SSX family.

9755:NSRP1
gene id: 9755:NSRP1
uniprot id: A0A2Y9FI27
uniprot id: A0A2Y9FI28
uniprot id: A0A455C4Z8
uniprot id: A0A455CAM8
names: Similarity
messages: Belongs to the NSRP1 family.

9755:NKAP
gene id: 9755:NKAP
uniprot id: A0A2Y9SYT5
names: Similarity
messages: Belongs to the NKAP family.

9755:ADAM10
gene id: 9755:ADAM10
uniprot id: A0A2Y9F656
uniprot id: A0A2Y9F6A0
uniprot id: A0A2Y9F7V7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:SF3B4
gene id: 9755:SF3B4
uniprot id: A0A2Y9F5E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B4 family.
messages: Nucleus

9755:NKX2-1
gene id: 9755:NKX2-1
uniprot id: A0A2Y9SD31
names: Subcellular Location Annotation
messages: Nucleus

9755:MRPL1
gene id: 9755:MRPL1
uniprot id: A0A2Y9F6Q1
names: Subcellular Location Annotation
messages: Mitochondrion

9755:CDK1
gene id: 9755:CDK1
uniprot id: A0A2Y9S5I9
names: Similarity
messages: Belongs to the protein kinase superfamily.

9755:NEK9
gene id: 9755:NEK9
uniprot id: A0A2Y9F861
uniprot id: A0A2Y9TJU9
uniprot id: A0A455BW44
names: Similarity
messages: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.

9755:GALNT18
gene id: 9755:GALNT18
uniprot id: A0A455C5U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane

9755:CASTOR2
gene id: 9755:CASTOR2
uniprot id: A0A2Y9SRS6
names: Similarity
messages: Belongs to the GATS family.

9755:NF2
gene id: 9755:NF2
uniprot id: A0A455AWW8
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

9755:BTN1A1
gene id: 9755:BTN1A1
uniprot id: A0A2Y9FQI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

9755:TMC4
gene id: 9755:TMC4
uniprot id: A0A455ACT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

9755:GRIK2
gene id: 9755:GRIK2
uniprot id: A0A455BN66
uniprot id: A0A455BNC8
uniprot id: A0A455BNW0
uniprot id: A0A455BRH5
uniprot id: A0A455C3B4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

9755:B3GALT1
gene id: 9755:B3GALT1
uniprot id: A0A2Y9F107
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9755:CNR2
gene id: 9755:CNR2
uniprot id: A0A2Y9FEU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9755:NRN1
gene id: 9755:NRN1
uniprot id: A0A2Y9FL24
uniprot id: A0A2Y9FM23
names: Similarity
messages: Belongs to the neuritin family.

9755:CXCR4
gene id: 9755:CXCR4
uniprot id: A0A2Y9FUW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell junction
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Late endosome
messages: Lysosome
messages: Membrane

9755:NTHL1
gene id: 9755:NTHL1
uniprot id: A0A2Y9EEP3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nth/MutY family.
messages: Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.
messages: Binds 1 [4Fe-4S] cluster. The cluster does not appear to play a role in catalysis, but is probably involved in the proper positioning of the enzyme along the DNA strand.
messages: Interacts with YBX1.
messages: Mitochondrion
messages: Nucleus

9755:LOC112066213
gene id: 9755:LOC112066213
uniprot id: A0A2Y9T6J0
names: Similarity
messages: Belongs to the SS18 family.

9755:TP53BP1
gene id: 9755:TP53BP1
uniprot id: A0A2Y9F345
uniprot id: A0A2Y9F360
uniprot id: A0A2Y9S6W1
names: Subcellular Location Annotation
messages: Nucleus

9755:PRPF38A
gene id: 9755:PRPF38A
uniprot id: A0A2Y9FTI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRP38 family.
messages: Component of the spliceosome B complex.
messages: Involved in pre-mRNA splicing as a component of the spliceosome.
messages: Nucleus

9755:AQR
gene id: 9755:AQR
uniprot id: A0A2Y9SEN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CWF11 family.
messages: Identified in the spliceosome C complex. Component of the XAB2 complex, a multimeric protein complex composed of XAB2, PRPF19, AQR, ZNF830, ISY1, and PPIE.
messages: Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.
messages: Nucleus

9755:NAXD
gene id: 9755:NAXD
uniprot id: A0A2Y9SJW0
uniprot id: A0A2Y9SKK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Mitochondrion

9755:LOC102994991
gene id: 9755:LOC102994991
uniprot id: A0A2Y9FQQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H3 family.
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus

9755:GINS3
gene id: 9755:GINS3
uniprot id: A0A2Y9FIB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS3/PSF3 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

9755:LOC102985689
gene id: 9755:LOC102985689
uniprot id: A0A455AKV7
names: Similarity
messages: Belongs to the serpin family.

9755:LOC102990004
gene id: 9755:LOC102990004
uniprot id: A0A2Y9SDX4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:GLO1
gene id: 9755:GLO1
uniprot id: A0A2Y9SK07
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

9755:CENPO
gene id: 9755:CENPO
uniprot id: A0A2Y9EI65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-O/MCM21 family.
messages: Nucleus

9755:CASP6
gene id: 9755:CASP6
uniprot id: A0A2Y9SHI6
names: Similarity
messages: Belongs to the peptidase C14A family.

9755:GABRG1
gene id: 9755:GABRG1
uniprot id: A0A2Y9T9X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9755:MID1
gene id: 9755:MID1
uniprot id: A0A2Y9RXG0
names: Subcellular Location Annotation
messages: cytoskeleton

9755:TNPO1
gene id: 9755:TNPO1
uniprot id: A0A2Y9F117
uniprot id: A0A2Y9F2E4
uniprot id: A0A455BIH3
uniprot id: A0A455BYA5
names: Subcellular Location Annotation
messages: Cytoplasm

9755:SYNPR
gene id: 9755:SYNPR
uniprot id: A0A2Y9STU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

9755:FABP1
gene id: 9755:FABP1
uniprot id: A0A2Y9EGY8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport.
messages: Cytoplasm
messages: Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.

9755:RNF146
gene id: 9755:RNF146
uniprot id: A0A2Y9FXF2
names: Domain
names: Function
names: PTM
names: Subcellular Location Annotation
messages: E3 ubiquitin-protein ligase that specifically binds poly-ADP-ribosylated proteins and mediates their ubiquitination and subsequent degradation.
messages: The WWE domain mediates non-covalent poly(ADP-ribose)-binding.
messages: Ubiquitinated; autoubiquitinated.
messages: cytosol

9755:RPS24
gene id: 9755:RPS24
uniprot id: A0A2Y9EIP0
uniprot id: A0A2Y9EJB3
uniprot id: A0A455AZE9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

9755:AMOTL2
gene id: 9755:AMOTL2
uniprot id: A0A2Y9FC34
uniprot id: A0A2Y9FCA9
uniprot id: A0A2Y9TH83
names: Similarity
messages: Belongs to the angiomotin family.

9755:GPRASP1
gene id: 9755:GPRASP1
uniprot id: A0A2Y9S7A2
names: Similarity
messages: Belongs to the GPRASP family.

9755:ACP1
gene id: 9755:ACP1
uniprot id: A0A2Y9FAZ1
uniprot id: A0A2Y9FBB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates.
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
messages: Cytoplasm

9755:CSTF2T
gene id: 9755:CSTF2T
uniprot id: A0A2Y9FGU9
names: Subcellular Location Annotation
messages: Nucleus

9755:LLGL2
gene id: 9755:LLGL2
uniprot id: A0A455C107
uniprot id: A0A455C108
uniprot id: A0A455C1Y7
uniprot id: A0A455C572
uniprot id: A0A455CAP3
names: Similarity
messages: Belongs to the WD repeat L(2)GL family.

9755:TFRC
gene id: 9755:TFRC
uniprot id: A0A2Y9EWS1
uniprot id: A0A455BI89
uniprot id: A0A455BXK2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Acts as a lipid sensor that regulates mitochondrial fusion by regulating activation of the JNK pathway.
messages: Homodimer; disulfide-linked.
messages: Melanosome
messages: Membrane
messages: Stearoylated.

9755:LOC102979665
gene id: 9755:LOC102979665
uniprot id: A0A2Y9FK90
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9755:MINDY4
gene id: 9755:MINDY4
uniprot id: A0A2Y9FW53
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
messages: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

9755:LOC102981913
gene id: 9755:LOC102981913
uniprot id: A0A2Y9SU50
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:SMPX
gene id: 9755:SMPX
uniprot id: A0A2Y9FM79
names: Function
names: Similarity
messages: Belongs to the SMPX family.
messages: Plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair.

9755:LOC102992680
gene id: 9755:LOC102992680
uniprot id: A0A2Y9SVF9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Cytoplasm
messages: Homodimer.

9755:CLIC1
gene id: 9755:CLIC1
uniprot id: A0A2Y9EY05
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cell membrane
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane
messages: Nucleus membrane

9755:YEATS2
gene id: 9755:YEATS2
uniprot id: A0A2Y9SNF1
uniprot id: A0A2Y9SUK2
uniprot id: A0A2Y9SWM7
names: Subcellular Location Annotation
messages: Nucleus

9755:MTO1
gene id: 9755:MTO1
uniprot id: A0A2Y9TCU0
uniprot id: A0A2Y9TIP7
uniprot id: A0A2Y9TJE2
uniprot id: A0A455C3J3
names: Function
names: Similarity
messages: Belongs to the MnmG family.
messages: Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs.

9755:GJA10
gene id: 9755:GJA10
uniprot id: A0A2Y9FP15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9755:GUCY2D
gene id: 9755:GUCY2D
uniprot id: A0A2Y9T1A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane
messages: Photoreceptor outer segment membrane

9755:ZKSCAN8
gene id: 9755:ZKSCAN8
uniprot id: A0A2Y9ENC9
names: Subcellular Location Annotation
messages: Nucleus

9755:LOC102994985
gene id: 9755:LOC102994985
uniprot id: A0A455BTR8
names: Similarity
messages: Belongs to the SF3A2 family.

9755:PYGB
gene id: 9755:PYGB
uniprot id: A0A455BYK3
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

9755:PCMT1
gene id: 9755:PCMT1
uniprot id: A0A2Y9ESP3
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

9755:MID2
gene id: 9755:MID2
uniprot id: A0A2Y9T0Q2
uniprot id: A0A2Y9T324
names: Subcellular Location Annotation
messages: cytoskeleton

9755:RHBDD3
gene id: 9755:RHBDD3
uniprot id: A0A2Y9EHT0
names: Subcellular Location Annotation
messages: Membrane

9755:NHSL1
gene id: 9755:NHSL1
uniprot id: A0A2Y9EXN7
uniprot id: A0A2Y9EY62
uniprot id: A0A2Y9SHQ5
uniprot id: A0A2Y9SP75
names: Similarity
messages: Belongs to the NHS family.

9755:KIF5A
gene id: 9755:KIF5A
uniprot id: A0A455BE25
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9755:SEC13
gene id: 9755:SEC13
uniprot id: A0A2Y9STD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Lysosome membrane

9755:LOC102987447
gene id: 9755:LOC102987447
uniprot id: A0A2Y9EF77
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

9755:CLPP
gene id: 9755:CLPP
uniprot id: A0A2Y9EVC0
uniprot id: A0A455C337
names: Similarity
messages: Belongs to the peptidase S14 family.

9755:ST3GAL3
gene id: 9755:ST3GAL3
uniprot id: A0A2Y9ST65
uniprot id: A0A2Y9SVJ3
uniprot id: A0A455AWR2
uniprot id: A0A455AYP3
uniprot id: A0A455BAI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9755:TRAF2
gene id: 9755:TRAF2
uniprot id: A0A455BWS5
uniprot id: A0A455C0D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

9755:TIMM8B
gene id: 9755:TIMM8B
uniprot id: A0A2Y9FRU5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

9755:GATAD2B
gene id: 9755:GATAD2B
uniprot id: A0A455BL45
names: Subcellular Location Annotation
messages: Nucleus

9755:TUBGCP2
gene id: 9755:TUBGCP2
uniprot id: A0A2Y9SII6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

9755:ID4
gene id: 9755:ID4
uniprot id: A0A2Y9SKF0
names: Subcellular Location Annotation
messages: Nucleus

9755:PTGDR
gene id: 9755:PTGDR
uniprot id: A0A2Y9FIP5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9755:BFSP1
gene id: 9755:BFSP1
uniprot id: A0A2Y9SSH0
uniprot id: A0A455C287
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: cell cortex
messages: cytoskeleton

9755:PAMR1
gene id: 9755:PAMR1
uniprot id: A0A2Y9FS68
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:LOC102982478
gene id: 9755:LOC102982478
uniprot id: A0A2Y9EJS7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
messages: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.

9755:PROM2
gene id: 9755:PROM2
uniprot id: A0A455BW13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prominin family.
messages: Membrane
messages: microvillus membrane

9755:BCL2
gene id: 9755:BCL2
uniprot id: A0A2Y9EML1
uniprot id: A0A455AGZ4
uniprot id: A0A455AHG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: Nucleus membrane

9755:SRPX
gene id: 9755:SRPX
uniprot id: A0A2Y9S0V2
uniprot id: A0A2Y9S4E5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:BCAT1
gene id: 9755:BCAT1
uniprot id: A0A2Y9EFR2
uniprot id: A0A2Y9EGY2
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

9755:CNP
gene id: 9755:CNP
uniprot id: A0A2Y9FRI5
uniprot id: A0A455C642
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 2H phosphoesterase superfamily. CNPase family.
messages: Exists as monomers and homodimers.
messages: May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin.
messages: Melanosome
messages: Membrane

9755:FOXP3
gene id: 9755:FOXP3
uniprot id: A0A455ANE4
uniprot id: A0A455ANP2
uniprot id: A0A455AQ40
uniprot id: A0A455AQI8
names: Subcellular Location Annotation
messages: Nucleus

9755:IDO1
gene id: 9755:IDO1
uniprot id: A0A455AM64
uniprot id: A0A455B0N5
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

9755:C16H11orf87
gene id: 9755:C16H11orf87
uniprot id: A0A2Y9TFL5
names: Subcellular Location Annotation
messages: Membrane

9755:AGT
gene id: 9755:AGT
uniprot id: A0A2Y9FNV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the serpin family.
messages: Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis.
messages: Secreted
messages: Stimulates aldosterone release.

9755:DOLK
gene id: 9755:DOLK
uniprot id: A0A455BWU7
uniprot id: A0A455BWV0
names: Similarity
messages: Belongs to the polyprenol kinase family.

9755:FAM193A
gene id: 9755:FAM193A
uniprot id: A0A2Y9ENL2
uniprot id: A0A455BGZ1
uniprot id: A0A455BK15
names: Similarity
messages: Belongs to the FAM193 family.

9755:PAEP
gene id: 9755:PAEP
uniprot id: A0A2Y9EYU7
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

9755:RPL36A
gene id: 9755:RPL36A
uniprot id: A0A2Y9FDA7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

9755:CERS5
gene id: 9755:CERS5
uniprot id: A0A2Y9SJ63
uniprot id: A0A455BTH7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

9755:INPP1
gene id: 9755:INPP1
uniprot id: A0A2Y9EKX4
uniprot id: A0A2Y9EMF4
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

9755:PRKACB
gene id: 9755:PRKACB
uniprot id: A0A2Y9ENR4
uniprot id: A0A2Y9EQ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.
messages: Nucleus

9755:CCDC126
gene id: 9755:CCDC126
uniprot id: A0A2Y9ETZ8
names: Subcellular Location Annotation
messages: Secreted

9755:LOC102992858
gene id: 9755:LOC102992858
uniprot id: A0A2Y9FQG4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9755:GPC4
gene id: 9755:GPC4
uniprot id: A0A2Y9T6V9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

9755:CAPN5
gene id: 9755:CAPN5
uniprot id: A0A455CBM7
names: Similarity
messages: Belongs to the peptidase C2 family.

9755:OTOGL
gene id: 9755:OTOGL
uniprot id: A0A2Y9SSQ4
uniprot id: A0A455BQG8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:SYNJ1
gene id: 9755:SYNJ1
uniprot id: A0A2Y9EEZ5
uniprot id: A0A2Y9SB89
uniprot id: A0A455BHI2
uniprot id: A0A455BX94
names: Similarity
messages: Belongs to the synaptojanin family.
messages: In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.

9755:LOC114488048
gene id: 9755:LOC114488048
uniprot id: A0A455CC17
names: Similarity
messages: Belongs to the GOLGA6 family.

9755:OVOL2
gene id: 9755:OVOL2
uniprot id: A0A2Y9EYB6
names: Subcellular Location Annotation
messages: Nucleus

9755:CCL25
gene id: 9755:CCL25
uniprot id: A0A2Y9TL60
uniprot id: A0A455C3M0
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.

9755:LOC112061881
gene id: 9755:LOC112061881
uniprot id: A0A455BQ40
names: Function
names: Similarity
messages: Belongs to the peptidase M54 family.
messages: Probable zinc metalloprotease.

9755:AP3M1
gene id: 9755:AP3M1
uniprot id: A0A2Y9EWY1
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

9755:RNFT1
gene id: 9755:RNFT1
uniprot id: A0A2Y9SY60
uniprot id: A0A455CB62
names: Subcellular Location Annotation
messages: Membrane

9755:LOC102979163
gene id: 9755:LOC102979163
uniprot id: A0A2Y9SU92
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin.
messages: Belongs to the MoaD family. MOCS2A subfamily.
messages: C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of MOCS3, then thiocarboxylated (-COSH) via the rhodanese domain of MOCS3.
messages: Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.
messages: This protein is produced by a bicistronic gene which also produces the large subunit (MOCS2B) from an overlapping reading frame.
messages: cytosol

9755:RNASEH1
gene id: 9755:RNASEH1
uniprot id: A0A2Y9EET9
uniprot id: A0A455BUZ2
names: Function
names: Similarity
messages: Belongs to the RNase H family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

9755:GTPBP8
gene id: 9755:GTPBP8
uniprot id: A0A2Y9FFG5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.

9755:MAP3K21
gene id: 9755:MAP3K21
uniprot id: A0A2Y9RYV2
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

9755:SEMA5A
gene id: 9755:SEMA5A
uniprot id: A0A2Y9SJU5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:CDC73
gene id: 9755:CDC73
uniprot id: A0A2Y9T7W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC73 family.
messages: Nucleus

9755:GDF9
gene id: 9755:GDF9
uniprot id: A0A2Y9EQC4
uniprot id: A0A2Y9EQK0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer or heterodimer (Potential). But, in contrast to other members of this family, cannot be disulfide-linked.
messages: Secreted

9755:IL2RG
gene id: 9755:IL2RG
uniprot id: A0A2Y9F3R3
uniprot id: A0A2Y9TAZ4
names: Subcellular Location Annotation
messages: Membrane

9755:HOXC4
gene id: 9755:HOXC4
uniprot id: A0A2Y9FL63
uniprot id: A0A455BGP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

9755:TBX18
gene id: 9755:TBX18
uniprot id: A0A2Y9FEV5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9755:LOC112065116
gene id: 9755:LOC112065116
uniprot id: A0A455C968
names: Subcellular Location Annotation
messages: Membrane

9755:HSD17B7
gene id: 9755:HSD17B7
uniprot id: A0A2Y9F3Q4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily.

9755:ARSL
gene id: 9755:ARSL
uniprot id: A0A2Y9FQV2
uniprot id: A0A2Y9FSR2
uniprot id: A0A2Y9FTJ5
uniprot id: A0A455BH66
names: Similarity
messages: Belongs to the sulfatase family.

9755:LOC102994170
gene id: 9755:LOC102994170
uniprot id: A0A455B0B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
messages: Belongs to the NMD3 family.
messages: Cytoplasm
messages: Nucleus

9755:ABCC5
gene id: 9755:ABCC5
uniprot id: A0A2Y9FEV6
names: Subcellular Location Annotation
messages: Membrane

9755:PTDSS2
gene id: 9755:PTDSS2
uniprot id: A0A2Y9EU56
uniprot id: A0A455AF62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:NR0B1
gene id: 9755:NR0B1
uniprot id: A0A2Y9ETD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus
messages: Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency.

9755:MYO16
gene id: 9755:MYO16
uniprot id: A0A2Y9SRC9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

9755:LPGAT1
gene id: 9755:LPGAT1
uniprot id: A0A2Y9TF61
uniprot id: A0A2Y9TIT4
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

9755:FOXN1
gene id: 9755:FOXN1
uniprot id: A0A2Y9FFU3
names: Subcellular Location Annotation
messages: Nucleus

9755:TBX2
gene id: 9755:TBX2
uniprot id: A0A2Y9SZP6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9755:CCDC149
gene id: 9755:CCDC149
uniprot id: A0A2Y9SCR5
names: Similarity
messages: Belongs to the CCDC149 family.

9755:ANAPC5
gene id: 9755:ANAPC5
uniprot id: A0A2Y9SJB2
uniprot id: A0A2Y9SKZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC5 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: spindle

9755:HEXB
gene id: 9755:HEXB
uniprot id: A0A2Y9S947
uniprot id: A0A2Y9S952
uniprot id: A0A2Y9SCC4
uniprot id: A0A2Y9SCC9
uniprot id: A0A455BII3
uniprot id: A0A455BIW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 20 family.
messages: Lysosome

9755:STIM1
gene id: 9755:STIM1
uniprot id: A0A455C7C4
uniprot id: A0A455C7J0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:TPH2
gene id: 9755:TPH2
uniprot id: A0A2Y9SMM9
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

9755:TSR2
gene id: 9755:TSR2
uniprot id: A0A2Y9F9I3
uniprot id: A0A455B2Q2
names: Function
names: Similarity
messages: Belongs to the TSR2 family.
messages: May be involved in 20S pre-rRNA processing.

9755:HOXD1
gene id: 9755:HOXD1
uniprot id: A0A2Y9F0G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family. Labial subfamily.
messages: Nucleus

9755:LOC102990686
gene id: 9755:LOC102990686
uniprot id: A0A2Y9FHI0
uniprot id: A0A2Y9SI31
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

9755:LOC102985261
gene id: 9755:LOC102985261
uniprot id: A0A2Y9SAD6
uniprot id: A0A2Y9SE30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

9755:PTPRB
gene id: 9755:PTPRB
uniprot id: A0A2Y9SJG2
uniprot id: A0A2Y9SQ99
uniprot id: A0A455BBV4
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily.

9755:ATAD1
gene id: 9755:ATAD1
uniprot id: A0A2Y9FKV4
uniprot id: A0A2Y9FLR2
uniprot id: A0A2Y9FMR2
uniprot id: A0A455ALV3
names: Similarity
messages: Belongs to the AAA ATPase family.

9755:LOC102990897
gene id: 9755:LOC102990897
uniprot id: A0A2Y9FPG1
names: Similarity
messages: Belongs to the cytochrome P450 family.

9755:PCNX1
gene id: 9755:PCNX1
uniprot id: A0A2Y9S6I8
uniprot id: A0A2Y9SCW0
uniprot id: A0A2Y9SED2
uniprot id: A0A455BVU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

9755:TSHZ2
gene id: 9755:TSHZ2
uniprot id: A0A2Y9T0I5
names: Similarity
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.

9755:RIOK2
gene id: 9755:RIOK2
uniprot id: A0A2Y9FC88
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

9755:LOC102989933
gene id: 9755:LOC102989933
uniprot id: A0A2Y9TG57
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:GPAT3
gene id: 9755:GPAT3
uniprot id: A0A2Y9FAC7
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

9755:FZD3
gene id: 9755:FZD3
uniprot id: A0A2Y9ETN6
uniprot id: A0A2Y9TAB6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:RORA
gene id: 9755:RORA
uniprot id: A0A2Y9T725
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

9755:F5
gene id: 9755:F5
uniprot id: A0A455B6S7
uniprot id: A0A455BKS6
names: Similarity
messages: Belongs to the multicopper oxidase family.

9755:TMEM132E
gene id: 9755:TMEM132E
uniprot id: A0A2Y9SYW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

9755:IL21
gene id: 9755:IL21
uniprot id: A0A2Y9F6I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-15/IL-21 family.
messages: Secreted

9755:LOC102991748
gene id: 9755:LOC102991748
uniprot id: A0A2Y9SMV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:LOC112062368
gene id: 9755:LOC112062368
uniprot id: A0A2Y9S7Y6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:MINPP1
gene id: 9755:MINPP1
uniprot id: A0A2Y9FKH1
uniprot id: A0A2Y9FKU4
names: Similarity
messages: Belongs to the histidine acid phosphatase family. MINPP1 subfamily.

9755:LOC102980239
gene id: 9755:LOC102980239
uniprot id: A0A2Y9EMK2
names: Similarity
messages: Belongs to the TACO1 family.

9755:GAREM1
gene id: 9755:GAREM1
uniprot id: A0A2Y9SCY1
uniprot id: A0A2Y9SG27
names: Similarity
messages: Belongs to the GAREM family.

9755:MON2
gene id: 9755:MON2
uniprot id: A0A2Y9EMU0
uniprot id: A0A2Y9ENX5
uniprot id: A0A455BDE4
uniprot id: A0A455BE22
uniprot id: A0A455BT18
names: Similarity
messages: Belongs to the MON2 family.

9755:SLC18B1
gene id: 9755:SLC18B1
uniprot id: A0A2Y9FHC3
uniprot id: A0A2Y9SQ23
uniprot id: A0A455C2T7
names: Subcellular Location Annotation
messages: Membrane

9755:FZD7
gene id: 9755:FZD7
uniprot id: A0A2Y9SSR6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:CCDC34
gene id: 9755:CCDC34
uniprot id: A0A2Y9F974
names: Subcellular Location Annotation
messages: flagellum

9755:INTS9
gene id: 9755:INTS9
uniprot id: A0A2Y9F4W3
uniprot id: A0A2Y9F5I6
uniprot id: A0A455C254
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS9 subfamily.
messages: Nucleus

9755:SCOC
gene id: 9755:SCOC
uniprot id: A0A2Y9FUU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCOC family.
messages: Positive regulator of amino acid starvation-induced autophagy.
messages: trans-Golgi network

9755:FXYD6
gene id: 9755:FXYD6
uniprot id: A0A2Y9EFX0
uniprot id: A0A2Y9EH62
uniprot id: A0A2Y9EHJ7
uniprot id: A0A2Y9TB75
names: Caution
names: Similarity
messages: Belongs to the FXYD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:C2
gene id: 9755:C2
uniprot id: A0A2Y9EW01
uniprot id: A0A455AIM2
uniprot id: A0A455AIY2
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9755:WRNIP1
gene id: 9755:WRNIP1
uniprot id: A0A2Y9SG95
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

9755:ST13
gene id: 9755:ST13
uniprot id: A0A2Y9ECP9
names: Similarity
messages: Belongs to the FAM10 family.

9755:USP13
gene id: 9755:USP13
uniprot id: A0A2Y9SR76
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

9755:LCTL
gene id: 9755:LCTL
uniprot id: A0A2Y9FP40
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

9755:ARID5B
gene id: 9755:ARID5B
uniprot id: A0A2Y9F579
uniprot id: A0A2Y9RY01
uniprot id: A0A2Y9S5F7
names: Similarity
messages: Belongs to the ARID5B family.

9755:TLR7
gene id: 9755:TLR7
uniprot id: A0A2Y9FEY3
uniprot id: A0A2Y9RY86
uniprot id: A0A455BKB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Endoplasmic reticulum membrane
messages: Endosome
messages: Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production.
messages: Lysosome
messages: Membrane
messages: phagosome

9755:LOC102995493
gene id: 9755:LOC102995493
uniprot id: A0A2Y9SS51
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:HYI
gene id: 9755:HYI
uniprot id: A0A2Y9F902
names: Function
names: Similarity
messages: Belongs to the hyi family.
messages: Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).

9755:AP1G1
gene id: 9755:AP1G1
uniprot id: A0A2Y9F666
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

9755:FREM2
gene id: 9755:FREM2
uniprot id: A0A2Y9F888
names: Similarity
messages: Belongs to the FRAS1 family.

9755:REV3L
gene id: 9755:REV3L
uniprot id: A0A2Y9RXR2
uniprot id: A0A2Y9RYD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

9755:IL20RB
gene id: 9755:IL20RB
uniprot id: A0A455B8Z5
names: Subcellular Location Annotation
messages: Membrane

9755:LOC102977564
gene id: 9755:LOC102977564
uniprot id: A0A455AFA0
uniprot id: A0A455AHL4
names: Function
names: Similarity
messages: Belongs to the CMP-Neu5Ac hydroxylase family.
messages: Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell-pathogen interactions. Catalyzes the conversion of CMP-N-acetylneuraminic acid (CMP-Neu5Ac) into its hydroxylated derivative CMP-N-glycolylneuraminic acid (CMP-Neu5Gc), a sialic acid abundantly expressed at the surface of many cells.

9755:ATP6AP2
gene id: 9755:ATP6AP2
uniprot id: A0A2Y9FEC1
uniprot id: A0A455ANU0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Lysosome membrane
messages: Membrane
messages: autophagosome membrane
messages: clathrin-coated vesicle membrane
messages: dendritic spine membrane
messages: synaptic vesicle membrane

9755:APOA4
gene id: 9755:APOA4
uniprot id: A0A2Y9F8I0
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

9755:SLC17A5
gene id: 9755:SLC17A5
uniprot id: A0A2Y9F6Y8
names: Subcellular Location Annotation
messages: Membrane

9755:SATB1
gene id: 9755:SATB1
uniprot id: A0A2Y9S0H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

9755:WNT7B
gene id: 9755:WNT7B
uniprot id: A0A455BTU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9755:PPARG
gene id: 9755:PPARG
uniprot id: A0A455AHG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Cytoplasm
messages: Heterodimer with other nuclear receptors.
messages: Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. May play a role in the regulation of circadian rhythm.
messages: Nucleus

9755:RAB29
gene id: 9755:RAB29
uniprot id: A0A2Y9F2Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

9755:FXYD3
gene id: 9755:FXYD3
uniprot id: A0A2Y9THJ3
names: Similarity
messages: Belongs to the FXYD family.

9755:CLTA
gene id: 9755:CLTA
uniprot id: A0A2Y9FNI1
uniprot id: A0A455BKU3
uniprot id: A0A455BL51
uniprot id: A0A455BL55
uniprot id: A0A455BLJ0
uniprot id: A0A455BP28
uniprot id: A0A455BP33
uniprot id: A0A455C0T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

9755:SAMD8
gene id: 9755:SAMD8
uniprot id: A0A2Y9EHV7
uniprot id: A0A2Y9EII9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

9755:CTTNBP2
gene id: 9755:CTTNBP2
uniprot id: A0A2Y9T6V6
uniprot id: A0A2Y9T6W2
names: Subcellular Location Annotation
messages: cell cortex
messages: dendritic spine

9755:LOC102981221
gene id: 9755:LOC102981221
uniprot id: A0A455AMS4
uniprot id: A0A455B1K1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:STT3B
gene id: 9755:STT3B
uniprot id: A0A2Y9S4F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

9755:LOC102977001
gene id: 9755:LOC102977001
uniprot id: A0A2Y9SM24
names: Function
names: Similarity
messages: Belongs to the GST superfamily. Omega family.
messages: Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA).

9755:AQP4
gene id: 9755:AQP4
uniprot id: A0A2Y9EN34
uniprot id: A0A2Y9SLW2
uniprot id: A0A455AJ74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

9755:PCSK1
gene id: 9755:PCSK1
uniprot id: A0A2Y9ESI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin, insulin and AGRP.
messages: Vesicle
messages: secretory vesicle

9755:NDUFAF4
gene id: 9755:NDUFAF4
uniprot id: A0A2Y9F7J0
names: Similarity
names: Subunit
messages: Belongs to the NDUFAF4 family.
messages: Binds calmodulin. Interacts with NDUFAF3.

9755:STX12
gene id: 9755:STX12
uniprot id: A0A2Y9FFI9
names: Similarity
messages: Belongs to the syntaxin family.

9755:OSBPL3
gene id: 9755:OSBPL3
uniprot id: A0A2Y9T3X0
uniprot id: A0A2Y9T852
uniprot id: A0A455BAQ1
names: Similarity
messages: Belongs to the OSBP family.

9755:LOC102974489
gene id: 9755:LOC102974489
uniprot id: A0A455ACF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

9755:MDN1
gene id: 9755:MDN1
uniprot id: A0A2Y9FLI0
uniprot id: A0A455BN87
uniprot id: A0A455BNF0
uniprot id: A0A455BRJ9
uniprot id: A0A455C3E0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the midasin family.
messages: Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits.
messages: Nucleus
messages: nucleolus
messages: nucleoplasm

9755:TENT5C
gene id: 9755:TENT5C
uniprot id: A0A2Y9EUF1
names: Similarity
messages: Belongs to the TENT family.

9755:PKIA
gene id: 9755:PKIA
uniprot id: A0A2Y9ELQ7
uniprot id: A0A455C4A2
uniprot id: A0A455C4J9
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

9755:UNK
gene id: 9755:UNK
uniprot id: A0A455C1Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unkempt family.
messages: Cytoplasm

9755:TPPP3
gene id: 9755:TPPP3
uniprot id: A0A2Y9FKY7
uniprot id: A0A2Y9SQ01
uniprot id: A0A455ACF1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Belongs to the TPPP family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9755:LOC102977525
gene id: 9755:LOC102977525
uniprot id: A0A2Y9ES16
names: Similarity
messages: Belongs to the PRORSD1 family.

9755:CNTNAP1
gene id: 9755:CNTNAP1
uniprot id: A0A455C1Q1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:GUF1
gene id: 9755:GUF1
uniprot id: A0A2Y9F8E4
uniprot id: A0A2Y9THJ2
uniprot id: A0A455BFZ2
uniprot id: A0A455BIE0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. LepA subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion inner membrane
messages: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.

9755:HAPLN1
gene id: 9755:HAPLN1
uniprot id: A0A2Y9EQK2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9755:ALOX12
gene id: 9755:ALOX12
uniprot id: A0A2Y9EF90
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:CA14
gene id: 9755:CA14
uniprot id: A0A2Y9EVY5
uniprot id: A0A455B7B0
uniprot id: A0A455BLA5
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

9755:LOC102993260
gene id: 9755:LOC102993260
uniprot id: A0A2Y9EFW7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics.
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane
messages: Interacts with chaperones HSP70 and HSP90; this interaction is required for initial targeting to mitochondria.
messages: Membrane
messages: Microsome membrane
messages: Mitochondrion inner membrane
messages: The omega-1 hydroxylase activity is stimulated by cytochrome b5.

9755:BOK
gene id: 9755:BOK
uniprot id: A0A455ATZ7
names: Similarity
messages: Belongs to the Bcl-2 family.

9755:LOC112067624
gene id: 9755:LOC112067624
uniprot id: A0A2Y9TJD6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:LOC102984834
gene id: 9755:LOC102984834
uniprot id: A0A2Y9TG15
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

9755:MKNK1
gene id: 9755:MKNK1
uniprot id: A0A2Y9FTZ9
uniprot id: A0A2Y9FX20
uniprot id: A0A2Y9SA71
names: Similarity
messages: Belongs to the protein kinase superfamily.

9755:SCN9A
gene id: 9755:SCN9A
uniprot id: A0A2Y9SH10
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

9755:GALNT6
gene id: 9755:GALNT6
uniprot id: A0A2Y9FCI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9755:DGKG
gene id: 9755:DGKG
uniprot id: A0A2Y9SRJ7
uniprot id: A0A455BFH6
uniprot id: A0A455BFJ1
uniprot id: A0A455BFZ9
uniprot id: A0A455BIK8
uniprot id: A0A455BIM3
uniprot id: A0A455BIM8
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

9755:NUDT5
gene id: 9755:NUDT5
uniprot id: A0A2Y9FRQ9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

9755:FRG1
gene id: 9755:FRG1
uniprot id: A0A2Y9TAK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRG1 family.
messages: Cajal body
messages: nucleolus

9755:TGM6
gene id: 9755:TGM6
uniprot id: A0A2Y9S6E9
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

9755:NUP188
gene id: 9755:NUP188
uniprot id: A0A2Y9EJS3
uniprot id: A0A2Y9SZB3
names: Subcellular Location Annotation
messages: nuclear pore complex

9755:DGKE
gene id: 9755:DGKE
uniprot id: A0A2Y9EVA7
uniprot id: A0A2Y9EWD7
uniprot id: A0A455BZK8
uniprot id: A0A455C3L6
uniprot id: A0A455CAD6
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

9755:PRDM2
gene id: 9755:PRDM2
uniprot id: A0A455B6H9
uniprot id: A0A455BI41
names: Subcellular Location Annotation
messages: Nucleus

9755:LGR6
gene id: 9755:LGR6
uniprot id: A0A2Y9TE16
names: Subcellular Location Annotation
messages: Membrane

9755:NR4A3
gene id: 9755:NR4A3
uniprot id: A0A2Y9ST59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9755:BACE1
gene id: 9755:BACE1
uniprot id: A0A2Y9F8H1
uniprot id: A0A2Y9FA78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Endosome
messages: Membrane
messages: Membrane raft
messages: Recycling endosome
messages: trans-Golgi network

9755:ECHS1
gene id: 9755:ECHS1
uniprot id: A0A2Y9EFJ1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

9755:PROX2
gene id: 9755:PROX2
uniprot id: A0A2Y9F8E7
names: Subcellular Location Annotation
messages: Nucleus

9755:XYLB
gene id: 9755:XYLB
uniprot id: A0A2Y9TAU9
uniprot id: A0A2Y9TCM2
uniprot id: A0A2Y9TEL7
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis.

9755:LOC102993447
gene id: 9755:LOC102993447
uniprot id: A0A455BMA8
uniprot id: A0A455BMI6
uniprot id: A0A455BN11
uniprot id: A0A455C2F3
names: Subcellular Location Annotation
messages: Membrane

9755:WIF1
gene id: 9755:WIF1
uniprot id: A0A2Y9SQL3
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9755:GDPD1
gene id: 9755:GDPD1
uniprot id: A0A2Y9EQ60
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

9755:AVPR1B
gene id: 9755:AVPR1B
uniprot id: A0A2Y9EEF3
uniprot id: A0A455B6A0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.

9755:MGAT1
gene id: 9755:MGAT1
uniprot id: A0A2Y9EGG5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.
messages: Membrane
messages: The cofactor is mostly bound to the substrate.

9755:COPS9
gene id: 9755:COPS9
uniprot id: A0A2Y9EW58
names: Similarity
messages: Belongs to the CSN9 family.

9755:SLC2A3
gene id: 9755:SLC2A3
uniprot id: A0A2Y9T5G3
uniprot id: A0A455BDG4
uniprot id: A0A455BSD9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane
messages: Cell projection
messages: Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane. Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate. Does not mediate fructose transport.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Perikaryon
messages: Transport is mediated via a series of conformation changes, switching between a conformation where the substrate-binding cavity is accessible from the outside, and a another conformation where it is accessible from the cytoplasm.

9755:SLF2
gene id: 9755:SLF2
uniprot id: A0A455AL94
uniprot id: A0A455ALK0
uniprot id: A0A455B010
names: Similarity
messages: Belongs to the FAM178 family.

9755:EGFR
gene id: 9755:EGFR
uniprot id: A0A2Y9S4T3
uniprot id: A0A455BBC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

9755:KHDRBS3
gene id: 9755:KHDRBS3
uniprot id: A0A2Y9T4G1
names: Similarity
messages: Belongs to the KHDRBS family.

9755:LOC112061948
gene id: 9755:LOC112061948
uniprot id: A0A2Y9RWA5
names: Similarity
messages: Belongs to the peptidase M14 family.

9755:LOC112063601
gene id: 9755:LOC112063601
uniprot id: A0A455CBQ6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:THOC7
gene id: 9755:THOC7
uniprot id: A0A2Y9EG26
uniprot id: A0A2Y9SMM7
uniprot id: A0A2Y9SQB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC7 family.
messages: Nucleus
messages: Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.

9755:TLR4
gene id: 9755:TLR4
uniprot id: A0A2Y9F2E5
uniprot id: A0A455BNF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

9755:LOC102986953
gene id: 9755:LOC102986953
uniprot id: A0A2Y9SGD7
names: Function
messages: Important for normal spermatogenesis and male fertility. Specifically required for progression to the post-meiotic stages of spermatocyte development. Seems to be necessary for normal expression levels of a number of testis-expressed gene transcripts, although its role in this process is unclear.

9755:UBE4A
gene id: 9755:UBE4A
uniprot id: A0A2Y9FIT7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm
messages: The U-box domain is required for the ubiquitin protein ligase activity.
messages: Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases. Also functions as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase. Mediates 'Lys-48'-linked polyubiquitination of substrates.

9755:ETV2
gene id: 9755:ETV2
uniprot id: A0A2Y9EGE7
uniprot id: A0A2Y9THH6
uniprot id: A0A2Y9TIM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9755:LOC102982287
gene id: 9755:LOC102982287
uniprot id: A0A455BM77
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:OAF
gene id: 9755:OAF
uniprot id: A0A2Y9TDY9
names: Similarity
messages: Belongs to the OAF family.

9755:CLCN1
gene id: 9755:CLCN1
uniprot id: A0A455BNL1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:CLPTM1L
gene id: 9755:CLPTM1L
uniprot id: A0A2Y9ENI9
uniprot id: A0A2Y9ST71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

9755:FMO2
gene id: 9755:FMO2
uniprot id: A0A455BIX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

9755:LOC102982254
gene id: 9755:LOC102982254
uniprot id: A0A2Y9SA87
names: Similarity
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.

9755:C1QBP
gene id: 9755:C1QBP
uniprot id: A0A2Y9T004
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAM33 family.
messages: Cell membrane

9755:ORC6
gene id: 9755:ORC6
uniprot id: A0A2Y9FGU5
uniprot id: A0A2Y9FH55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC6 family.
messages: Nucleus

9755:OPN1SW
gene id: 9755:OPN1SW
uniprot id: A0A2Y9TF00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: Photoreceptor inner segment
messages: photoreceptor outer segment

9755:ZFP69
gene id: 9755:ZFP69
uniprot id: A0A455AY82
uniprot id: A0A455BCA0
names: Subcellular Location Annotation
messages: Nucleus

9755:MYT1
gene id: 9755:MYT1
uniprot id: A0A2Y9EKN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYT1 family.
messages: Nucleus

9755:MARVELD3
gene id: 9755:MARVELD3
uniprot id: A0A2Y9F618
names: Subcellular Location Annotation
messages: Membrane

9755:GUCY1A1
gene id: 9755:GUCY1A1
uniprot id: A0A2Y9F1Z8
uniprot id: A0A455BF01
uniprot id: A0A455BF25
uniprot id: A0A455BHG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

9755:LOC102994172
gene id: 9755:LOC102994172
uniprot id: A0A2Y9F3Q1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9755:CHST8
gene id: 9755:CHST8
uniprot id: A0A2Y9FMF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

9755:MIX23
gene id: 9755:MIX23
uniprot id: A0A2Y9EZR0
uniprot id: A0A2Y9F1L6
uniprot id: A0A455BM05
names: Similarity
messages: Belongs to the MIX23 family.

9755:PFDN5
gene id: 9755:PFDN5
uniprot id: A0A2Y9FN76
names: Similarity
messages: Belongs to the prefoldin subunit alpha family.

9755:STK11IP
gene id: 9755:STK11IP
uniprot id: A0A455AMI7
uniprot id: A0A455AMQ0
uniprot id: A0A455B1A6
uniprot id: A0A455B1B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STK11IP family.
messages: Cytoplasm

9755:TSPAN1
gene id: 9755:TSPAN1
uniprot id: A0A2Y9FX00
uniprot id: A0A455BB88
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:PSEN2
gene id: 9755:PSEN2
uniprot id: A0A2Y9TCD4
uniprot id: A0A455B5I4
uniprot id: A0A455B6E1
uniprot id: A0A455BJV5
uniprot id: A0A455BJW0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: The PAL motif is required for normal active site conformation.

9755:FEV
gene id: 9755:FEV
uniprot id: A0A2Y9FUM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9755:RAD51
gene id: 9755:RAD51
uniprot id: A0A2Y9S745
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Nucleus
messages: Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR). Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Recruited to resolve stalled replication forks during replication stress. Also involved in interstrand cross-link repair.

9755:POLR2K
gene id: 9755:POLR2K
uniprot id: A0A2Y9S2L7
names: Similarity
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.

9755:STX3
gene id: 9755:STX3
uniprot id: A0A2Y9TDJ5
uniprot id: A0A2Y9TJ40
uniprot id: A0A2Y9TJR5
uniprot id: A0A455C5S2
uniprot id: A0A455C611
uniprot id: A0A455C6S6
uniprot id: A0A455C913
uniprot id: A0A455CBP2
names: Similarity
messages: Belongs to the syntaxin family.

9755:LOC102984795
gene id: 9755:LOC102984795
uniprot id: A0A2Y9FA81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

9755:ACKR4
gene id: 9755:ACKR4
uniprot id: A0A2Y9FCG5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9755:CIAO2A
gene id: 9755:CIAO2A
uniprot id: A0A2Y9T8X6
names: Similarity
messages: Belongs to the MIP18 family.

9755:RPS7
gene id: 9755:RPS7
uniprot id: A0A2Y9SBQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eS7 family.
messages: centrosome

9755:HS6ST2
gene id: 9755:HS6ST2
uniprot id: A0A2Y9EXC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

9755:LOC102986673
gene id: 9755:LOC102986673
uniprot id: A0A2Y9F971
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

9755:NDUFB4
gene id: 9755:NDUFB4
uniprot id: A0A2Y9ELR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB4 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9755:SLC30A4
gene id: 9755:SLC30A4
uniprot id: A0A2Y9FH50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

9755:RPS6KA5
gene id: 9755:RPS6KA5
uniprot id: A0A2Y9TFC0
uniprot id: A0A455BTR4
uniprot id: A0A455C847
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

9755:LOC102996195
gene id: 9755:LOC102996195
uniprot id: A0A2Y9EWV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

9755:LOC102988596
gene id: 9755:LOC102988596
uniprot id: A0A2Y9FJC7
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

9755:DUS4L
gene id: 9755:DUS4L
uniprot id: A0A2Y9EMZ0
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.

9755:GALNT9
gene id: 9755:GALNT9
uniprot id: A0A2Y9SM08
uniprot id: A0A455AI65
uniprot id: A0A455AIL3
uniprot id: A0A455AIL7
uniprot id: A0A455AK55
uniprot id: A0A455AK60
uniprot id: A0A455AWJ6
uniprot id: A0A455AWK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9755:MYO19
gene id: 9755:MYO19
uniprot id: A0A455BZF3
uniprot id: A0A455BZF4
uniprot id: A0A455C0H3
uniprot id: A0A455C3E2
uniprot id: A0A455CAC2
uniprot id: A0A455CAC3
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:IFI6
gene id: 9755:IFI6
uniprot id: A0A455BIT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFI6/IFI27 family.
messages: Membrane

9755:RBM8A
gene id: 9755:RBM8A
uniprot id: A0A2Y9FWJ4
uniprot id: A0A2Y9FXH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RBM8A family.
messages: Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
messages: Cytoplasm
messages: Heterodimer with MAGOH. Part of the mRNA splicing-dependent exon junction complex (EJC) complex; the core complex contains CASC3, EIF4A3, MAGOH and RBM8A.
messages: Nucleus
messages: Nucleus speckle

9755:KPNA1
gene id: 9755:KPNA1
uniprot id: A0A2Y9SJ29
names: Function
names: Similarity
messages: Belongs to the importin alpha family.
messages: Functions in nuclear protein import.

9755:LHFPL1
gene id: 9755:LHFPL1
uniprot id: A0A2Y9EUG8
names: Subcellular Location Annotation
messages: Membrane

9755:LOC112067641
gene id: 9755:LOC112067641
uniprot id: A0A2Y9TKX4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:TRIQK
gene id: 9755:TRIQK
uniprot id: A0A2Y9F2H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIQK family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:GRB14
gene id: 9755:GRB14
uniprot id: A0A2Y9SNV6
uniprot id: A0A455ADB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

9755:SLC16A12
gene id: 9755:SLC16A12
uniprot id: A0A2Y9SMG6
names: Subcellular Location Annotation
messages: Membrane

9755:DDX5
gene id: 9755:DDX5
uniprot id: A0A2Y9FNJ9
uniprot id: A0A455C2B4
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.

9755:FLI1
gene id: 9755:FLI1
uniprot id: A0A2Y9FU84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9755:ATG9B
gene id: 9755:ATG9B
uniprot id: A0A455BBL4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

9755:RAMP3
gene id: 9755:RAMP3
uniprot id: A0A2Y9EXG5
uniprot id: A0A455BB99
uniprot id: A0A455BBG7
uniprot id: A0A455BDP3
uniprot id: A0A455BQA0
names: Similarity
messages: Belongs to the RAMP family.

9755:OLFM4
gene id: 9755:OLFM4
uniprot id: A0A2Y9FBY4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:LOC102978080
gene id: 9755:LOC102978080
uniprot id: A0A2Y9SIX4
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.

9755:ATP6V1G2
gene id: 9755:ATP6V1G2
uniprot id: A0A2Y9EW86
uniprot id: A0A455AHH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

9755:HACD2
gene id: 9755:HACD2
uniprot id: A0A2Y9ENY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:LOC112062599
gene id: 9755:LOC112062599
uniprot id: A0A455AP01
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

9755:IPO11
gene id: 9755:IPO11
uniprot id: A0A2Y9FTS5
names: Subcellular Location Annotation
messages: Cytoplasm

9755:UTP25
gene id: 9755:UTP25
uniprot id: A0A2Y9EWS9
uniprot id: A0A2Y9EWT6
uniprot id: A0A2Y9EY71
uniprot id: A0A455B5T1
uniprot id: A0A455B6P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP25 family.
messages: nucleolus

9755:ACSS3
gene id: 9755:ACSS3
uniprot id: A0A2Y9F581
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

9755:VPS37C
gene id: 9755:VPS37C
uniprot id: A0A455C857
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

9755:ZGPAT
gene id: 9755:ZGPAT
uniprot id: A0A2Y9T444
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with CHD4/Mi-2; the interaction is direct.
messages: Nucleus

9755:LRP1B
gene id: 9755:LRP1B
uniprot id: A0A2Y9SQY7
names: Caution
names: Similarity
messages: Belongs to the LDLR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:LOC102986428
gene id: 9755:LOC102986428
uniprot id: A0A2Y9T266
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:NDUFB6
gene id: 9755:NDUFB6
uniprot id: A0A2Y9F7Q9
uniprot id: A0A455BM85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB6 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9755:DCC
gene id: 9755:DCC
uniprot id: A0A455AHF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. DCC family.
messages: Membrane

9755:CRYBG3
gene id: 9755:CRYBG3
uniprot id: A0A2Y9SJ52
uniprot id: A0A455C227
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

9755:GALNT12
gene id: 9755:GALNT12
uniprot id: A0A2Y9T126
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9755:CDH4
gene id: 9755:CDH4
uniprot id: A0A2Y9SZV9
uniprot id: A0A455CAL5
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

9755:HS3ST1
gene id: 9755:HS3ST1
uniprot id: A0A2Y9EQ63
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9755:WDR48
gene id: 9755:WDR48
uniprot id: A0A2Y9F7U8
uniprot id: A0A2Y9F884
uniprot id: A0A455AIN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR48 family.
messages: Late endosome

9755:LOC102996045
gene id: 9755:LOC102996045
uniprot id: A0A455BGV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

9755:INSL6
gene id: 9755:INSL6
uniprot id: A0A2Y9FH29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

9755:MTOR
gene id: 9755:MTOR
uniprot id: A0A2Y9SVG2
names: Similarity
messages: Belongs to the PI3/PI4-kinase family.

9755:LOC102987040
gene id: 9755:LOC102987040
uniprot id: A0A2Y9S0A0
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

9755:RUSF1
gene id: 9755:RUSF1
uniprot id: A0A2Y9F5L1
uniprot id: A0A2Y9RYK9
uniprot id: A0A455C9Z5
names: Similarity
messages: Belongs to the RUS1 family.

9755:SSU72
gene id: 9755:SSU72
uniprot id: A0A2Y9FU95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSU72 phosphatase family.
messages: Nucleus
messages: Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination.

9755:OXR1
gene id: 9755:OXR1
uniprot id: A0A2Y9T3Q1
uniprot id: A0A2Y9T5J5
uniprot id: A0A2Y9T7K2
uniprot id: A0A2Y9T7K6
uniprot id: A0A2Y9T9T2
uniprot id: A0A2Y9TC27
uniprot id: A0A455C859
names: Similarity
messages: Belongs to the OXR1 family.

9755:FOXN2
gene id: 9755:FOXN2
uniprot id: A0A2Y9FAA0
uniprot id: A0A2Y9S8B4
names: Subcellular Location Annotation
messages: Nucleus

9755:LOC102991297
gene id: 9755:LOC102991297
uniprot id: A0A2Y9SCT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C56 family.
messages: Membrane raft

9755:SKP1
gene id: 9755:SKP1
uniprot id: A0A2Y9F2A9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SKP1 family.
messages: Component of multiple SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complexes formed of CUL1, SKP1, RBX1 and a variable F-box domain-containing protein as substrate-specific subunit.
messages: Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1.
messages: The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component.

9755:UCN3
gene id: 9755:UCN3
uniprot id: A0A2Y9EK38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Binds with high affinity to CRF receptors 2-alpha and 2-beta.
messages: Secreted
messages: Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.

9755:IMMT
gene id: 9755:IMMT
uniprot id: A0A2Y9EN12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic60 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

9755:PDE1A
gene id: 9755:PDE1A
uniprot id: A0A2Y9SI23
uniprot id: A0A2Y9SKZ3
uniprot id: A0A2Y9SKZ9
uniprot id: A0A2Y9SQQ8
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9755:FAM118B
gene id: 9755:FAM118B
uniprot id: A0A455AC12
uniprot id: A0A455AD21
names: Similarity
messages: Belongs to the FAM118 family.

9755:BMP10
gene id: 9755:BMP10
uniprot id: A0A2Y9FMA1
names: Similarity
messages: Belongs to the TGF-beta family.

9755:NCBP2L
gene id: 9755:NCBP2L
uniprot id: A0A455ARM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRM NCBP2 family.
messages: Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U snRNA and intronless mRNAs export from the nucleus. The CBC complex is essential for a pioneer round of mRNA translation, before steady state translation when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. The pioneer round of mRNA translation mediated by the CBC complex plays a central role in nonsense-mediated mRNA decay (NMD), NMD only taking place in mRNAs bound to the CBC complex, but not on eIF4E-bound mRNAs. The CBC complex enhances NMD in mRNAs containing at least one exon-junction complex (EJC), promoting the interaction between upf1 and upf2. The CBC complex is also involved in 'failsafe' NMD, which is independent of the EJC complex, while it does not participate in Staufen-mediated mRNA decay (SMD). During cell proliferation, the CBC complex is also involved in microRNAs (miRNAs) biogenesis via its interaction with srrt/ars2, thereby being required for miRNA-mediated RNA interference. The CBC complex also acts as a negative regulator of parn, thereby acting as an inhibitor of mRNA deadenylation. In the CBC complex, ncbp2/cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp1/cbp80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure. The conventional cap-binding complex with NCBP2 binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus.
messages: Component of the nuclear cap-binding complex (CBC), a heterodimer composed of ncbp1/cbp80 and ncbp2/cbp20 that interacts with m7GpppG-capped RNA.
messages: Nucleus

9755:LGR5
gene id: 9755:LGR5
uniprot id: A0A2Y9EYN4
uniprot id: A0A2Y9EZ42
uniprot id: A0A2Y9EZN6
names: Subcellular Location Annotation
messages: Membrane

9755:GHR
gene id: 9755:GHR
uniprot id: A0A2Y9F9G9
uniprot id: A0A455BI91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Cell membrane
messages: Membrane
messages: On growth hormone (GH) binding, forms homodimers and binds JAK2 via a box 1-containing domain. Binding to SOCS3 inhibits JAK2 activation, binding to CIS and SOCS2 inhibits STAT5 activation.
messages: The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.

9755:AVP
gene id: 9755:AVP
uniprot id: A0A2Y9S2Y7
names: Similarity
messages: Belongs to the vasopressin/oxytocin family.

9755:MEMO1
gene id: 9755:MEMO1
uniprot id: A0A2Y9SFK4
names: Similarity
messages: Belongs to the MEMO1 family.

9755:TMEM131L
gene id: 9755:TMEM131L
uniprot id: A0A2Y9SUN7
uniprot id: A0A2Y9T0L7
uniprot id: A0A2Y9T2S2
uniprot id: A0A455BF48
uniprot id: A0A455BFM8
uniprot id: A0A455BFS5
uniprot id: A0A455BUT6
names: Similarity
messages: Belongs to the TMEM131 family.

9755:SYN3
gene id: 9755:SYN3
uniprot id: A0A455BCB1
uniprot id: A0A455BEL5
names: Similarity
messages: Belongs to the synapsin family.

9755:USP34
gene id: 9755:USP34
uniprot id: A0A2Y9TEJ6
uniprot id: A0A2Y9TJS1
names: Similarity
messages: Belongs to the peptidase C19 family.

9755:LARP7
gene id: 9755:LARP7
uniprot id: A0A2Y9F8V2
uniprot id: A0A2Y9F9I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LARP7 family.
messages: nucleoplasm

9755:HMGCL
gene id: 9755:HMGCL
uniprot id: A0A2Y9FEQ9
uniprot id: A0A2Y9SS54
uniprot id: A0A455B3N1
uniprot id: A0A455B423
uniprot id: A0A455B686
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HMG-CoA lyase family.
messages: Homodimer; disulfide-linked. Can also form homotetramers.
messages: Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.

9755:LOC102992785
gene id: 9755:LOC102992785
uniprot id: A0A455BZH2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 27 family.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

9755:PFDN4
gene id: 9755:PFDN4
uniprot id: A0A2Y9T6H6
uniprot id: A0A2Y9T8I1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

9755:HRH1
gene id: 9755:HRH1
uniprot id: A0A2Y9EE52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9755:LOC102987348
gene id: 9755:LOC102987348
uniprot id: A0A2Y9FD76
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

9755:TIPRL
gene id: 9755:TIPRL
uniprot id: A0A2Y9F476
uniprot id: A0A2Y9F4Y5
uniprot id: A0A2Y9F5V5
names: Similarity
messages: Belongs to the TIP41 family.

9755:FAR1
gene id: 9755:FAR1
uniprot id: A0A2Y9FF64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acyl-CoA reductase family.
messages: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
messages: Peroxisome membrane

9755:LOC102994714
gene id: 9755:LOC102994714
uniprot id: A0A2Y9T1C9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:ELP3
gene id: 9755:ELP3
uniprot id: A0A455BMR3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.

9755:HARS1
gene id: 9755:HARS1
uniprot id: A0A2Y9ETK2
uniprot id: A0A455BK36
uniprot id: A0A455BZA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

9755:SPIB
gene id: 9755:SPIB
uniprot id: A0A2Y9TB93
uniprot id: A0A2Y9TF22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9755:VSX1
gene id: 9755:VSX1
uniprot id: A0A2Y9EMA5
names: Subcellular Location Annotation
messages: Nucleus

9755:STX19
gene id: 9755:STX19
uniprot id: A0A2Y9EFJ3
names: Similarity
messages: Belongs to the syntaxin family.

9755:MSMP
gene id: 9755:MSMP
uniprot id: A0A455BKW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-microseminoprotein family.
messages: Secreted

9755:TULP4
gene id: 9755:TULP4
uniprot id: A0A2Y9SLA0
names: Similarity
messages: Belongs to the TUB family.

9755:GLB1L2
gene id: 9755:GLB1L2
uniprot id: A0A2Y9T9K4
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

9755:LAMA3
gene id: 9755:LAMA3
uniprot id: A0A2Y9FN43
uniprot id: A0A2Y9SHB7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

9755:PSMD4
gene id: 9755:PSMD4
uniprot id: A0A2Y9FTU7
uniprot id: A0A2Y9FVX6
uniprot id: A0A455BL63
names: Similarity
messages: Belongs to the proteasome subunit S5A family.

9755:NUDT2
gene id: 9755:NUDT2
uniprot id: A0A2Y9EF85
names: Similarity
messages: Belongs to the Nudix hydrolase family.

9755:EEF2K
gene id: 9755:EEF2K
uniprot id: A0A2Y9EJC7
uniprot id: A0A455BYM0
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. Alpha-type protein kinase family.
messages: Monomer or homodimer.
messages: Undergoes calcium/calmodulin-dependent intramolecular autophosphorylation, and this results in it becoming partially calcium/calmodulin-independent.

9755:LOC102996439
gene id: 9755:LOC102996439
uniprot id: A0A2Y9SZD4
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

9755:ISL1
gene id: 9755:ISL1
uniprot id: A0A2Y9EWU9
names: Subcellular Location Annotation
messages: Nucleus

9755:BTNL9
gene id: 9755:BTNL9
uniprot id: A0A2Y9EFV1
uniprot id: A0A455BZP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

9755:MNAT1
gene id: 9755:MNAT1
uniprot id: A0A2Y9TD00
uniprot id: A0A2Y9TD15
uniprot id: A0A2Y9TH04
uniprot id: A0A455BS17
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with CDK7 and cyclin H.
messages: Nucleus
messages: Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.

9755:IL20
gene id: 9755:IL20
uniprot id: A0A2Y9EEH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

9755:PTH2R
gene id: 9755:PTH2R
uniprot id: A0A2Y9SS07
names: Subcellular Location Annotation
messages: Membrane

9755:IMMP2L
gene id: 9755:IMMP2L
uniprot id: A0A2Y9T2W0
uniprot id: A0A455BAE8
uniprot id: A0A455BCJ5
uniprot id: A0A455BP62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26 family. IMP2 subfamily.
messages: Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO.
messages: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
messages: Membrane
messages: Mitochondrion inner membrane

9755:LMOD1
gene id: 9755:LMOD1
uniprot id: A0A2Y9T9S5
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

9755:ATG3
gene id: 9755:ATG3
uniprot id: A0A2Y9EJG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG3 family.
messages: Cytoplasm

9755:TAS2R60
gene id: 9755:TAS2R60
uniprot id: A0A2Y9T6S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

9755:JOSD2
gene id: 9755:JOSD2
uniprot id: A0A455ANZ3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:P2RY1
gene id: 9755:P2RY1
uniprot id: A0A455B8M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9755:DMD
gene id: 9755:DMD
uniprot id: A0A455APP7
uniprot id: A0A455APQ2
uniprot id: A0A455APX7
uniprot id: A0A455APY4
uniprot id: A0A455ART1
uniprot id: A0A455ARU2
uniprot id: A0A455B3M1
names: Subcellular Location Annotation
messages: cytoskeleton

9755:CWC15
gene id: 9755:CWC15
uniprot id: A0A2Y9F4U8
names: Similarity
messages: Belongs to the CWC15 family.

9755:AGK
gene id: 9755:AGK
uniprot id: A0A2Y9EJ26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AGK family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

9755:RBL1
gene id: 9755:RBL1
uniprot id: A0A2Y9SZP4
uniprot id: A0A2Y9T1B4
uniprot id: A0A2Y9T7Q3
uniprot id: A0A455C1A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

9755:SNURF
gene id: 9755:SNURF
uniprot id: A0A2Y9FFW4
names: Similarity
messages: Belongs to the SNURF family.

9755:LOC102990790
gene id: 9755:LOC102990790
uniprot id: A0A2Y9FJ74
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:GDF10
gene id: 9755:GDF10
uniprot id: A0A2Y9FAZ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer.
messages: Secreted

9755:LOC102981884
gene id: 9755:LOC102981884
uniprot id: A0A2Y9SAS9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:CAMKMT
gene id: 9755:CAMKMT
uniprot id: A0A2Y9S7T2
uniprot id: A0A2Y9S8F1
uniprot id: A0A2Y9SFX6
uniprot id: A0A455BUB0
uniprot id: A0A455BXR9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9755:FXR1
gene id: 9755:FXR1
uniprot id: A0A2Y9F6V1
uniprot id: A0A2Y9F760
uniprot id: A0A2Y9F778
uniprot id: A0A2Y9F7N7
uniprot id: A0A2Y9F7P1
uniprot id: A0A2Y9F8R6
uniprot id: A0A455BEB7
uniprot id: A0A455BTZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMR1 family.
messages: Cytoplasmic ribonucleoprotein granule
messages: Nucleus envelope
messages: Postsynapse
messages: Synapse
messages: dendritic spine

9755:TIGD5
gene id: 9755:TIGD5
uniprot id: A0A2Y9F2H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tigger transposable element derived protein family.
messages: Nucleus

9755:TMEM231
gene id: 9755:TMEM231
uniprot id: A0A2Y9F8X1
uniprot id: A0A455AC47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM231 family.
messages: Membrane
messages: Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling.
messages: cilium membrane

9755:YIPF1
gene id: 9755:YIPF1
uniprot id: A0A2Y9FQ27
uniprot id: A0A455BMR9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Late endosome membrane
messages: Membrane
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

9755:TMEM181
gene id: 9755:TMEM181
uniprot id: A0A2Y9SHZ0
names: Subcellular Location Annotation
messages: Membrane

9755:LOC112067041
gene id: 9755:LOC112067041
uniprot id: A0A2Y9TBH6
names: Function
names: Similarity
messages: Belongs to the proline oxidase family.
messages: Converts proline to delta-1-pyrroline-5-carboxylate.

9755:POLR3F
gene id: 9755:POLR3F
uniprot id: A0A2Y9F4A6
uniprot id: A0A455C1J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

9755:BTG2
gene id: 9755:BTG2
uniprot id: A0A2Y9F7A7
names: Similarity
messages: Belongs to the BTG family.

9755:TBC1D31
gene id: 9755:TBC1D31
uniprot id: A0A2Y9T4C1
uniprot id: A0A2Y9T8P6
names: Function
names: Subcellular Location Annotation
messages: Molecular adapter which is involved in cilium biogenesis. Part of a functional complex including OFD1 a centriolar protein involved in cilium assembly. Could regulate the cAMP-dependent phosphorylation of OFD1, and its subsequent ubiquitination by PJA2 which ultimately leads to its proteasomal degradation.
messages: centriolar satellite
messages: cilium basal body

9755:CMTM5
gene id: 9755:CMTM5
uniprot id: A0A2Y9S6A9
uniprot id: A0A455BRV0
uniprot id: A0A455BUH1
names: Subcellular Location Annotation
messages: Membrane

9755:RHBDL2
gene id: 9755:RHBDL2
uniprot id: A0A2Y9SR99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Membrane

9755:SLC7A2
gene id: 9755:SLC7A2
uniprot id: A0A2Y9TEE3
uniprot id: A0A455AKL7
uniprot id: A0A455AM99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

9755:DUSP3
gene id: 9755:DUSP3
uniprot id: A0A2Y9FPB9
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

9755:RPL24
gene id: 9755:RPL24
uniprot id: A0A2Y9EMK7
uniprot id: A0A455C0V0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

9755:ARSJ
gene id: 9755:ARSJ
uniprot id: A0A2Y9EX66
names: Similarity
messages: Belongs to the sulfatase family.

9755:UTS2B
gene id: 9755:UTS2B
uniprot id: A0A2Y9FL82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urotensin-2 family.
messages: Secreted

9755:LOC102983359
gene id: 9755:LOC102983359
uniprot id: A0A2Y9F0F4
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

9755:DPY30
gene id: 9755:DPY30
uniprot id: A0A2Y9EGV5
names: Similarity
messages: Belongs to the dpy-30 family.

9755:LOC102980216
gene id: 9755:LOC102980216
uniprot id: A0A2Y9SNJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

9755:EPHA3
gene id: 9755:EPHA3
uniprot id: A0A2Y9SIN9
uniprot id: A0A2Y9SKA7
names: Subcellular Location Annotation
messages: Membrane

9755:GALNT7
gene id: 9755:GALNT7
uniprot id: A0A2Y9T8G8
uniprot id: A0A2Y9TA32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9755:NECTIN3
gene id: 9755:NECTIN3
uniprot id: A0A2Y9SC22
uniprot id: A0A2Y9SI15
uniprot id: A0A2Y9SJM3
names: Similarity
messages: Belongs to the nectin family.

9755:RARG
gene id: 9755:RARG
uniprot id: A0A2Y9SQW5
uniprot id: A0A455BEE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

9755:CLSPN
gene id: 9755:CLSPN
uniprot id: A0A2Y9FE62
names: Subcellular Location Annotation
messages: Nucleus

9755:MRPS11
gene id: 9755:MRPS11
uniprot id: A0A2Y9FGU7
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

9755:NUDT6
gene id: 9755:NUDT6
uniprot id: A0A2Y9F6S9
uniprot id: A0A2Y9S9V0
uniprot id: A0A455BGX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Cytoplasm
messages: May contribute to the regulation of cell proliferation.
messages: Mitochondrion
messages: Monomer and homodimer.
messages: Nucleus

9755:POLR2M
gene id: 9755:POLR2M
uniprot id: A0A2Y9F152
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRINL1 family.
messages: Nucleus

9755:DUSP4
gene id: 9755:DUSP4
uniprot id: A0A455AM90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

9755:MRPL44
gene id: 9755:MRPL44
uniprot id: A0A2Y9ETH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease III family. Mitochondrion-specific ribosomal protein mL44 subfamily.
messages: Mitochondrion

9755:SPATS2
gene id: 9755:SPATS2
uniprot id: A0A2Y9ERV1
names: Similarity
messages: Belongs to the SPATS2 family.

9755:SBF2
gene id: 9755:SBF2
uniprot id: A0A2Y9S861
uniprot id: A0A2Y9SEX4
uniprot id: A0A455C7G8
uniprot id: A0A455C9C0
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

9755:CENPBD1P
gene id: 9755:CENPBD1P
uniprot id: A0A2Y9FK99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tigger transposable element derived protein family.
messages: Nucleus

9755:LOC102981335
gene id: 9755:LOC102981335
uniprot id: A0A2Y9FAI5
names: Similarity
messages: Belongs to the FAH family.

9755:PGPEP1L
gene id: 9755:PGPEP1L
uniprot id: A0A455C504
names: Similarity
messages: Belongs to the peptidase C15 family.

9755:B4GALNT4
gene id: 9755:B4GALNT4
uniprot id: A0A2Y9TCT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane
messages: Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.

9755:HEATR5B
gene id: 9755:HEATR5B
uniprot id: A0A2Y9SF38
names: Similarity
messages: Belongs to the HEATR5 family.

9755:LOC114484675
gene id: 9755:LOC114484675
uniprot id: A0A2Y9F8A0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9755:CCNDBP1
gene id: 9755:CCNDBP1
uniprot id: A0A2Y9FE35
names: Similarity
names: Subunit
messages: Belongs to the CCNDBP1 family.
messages: Interacts with CCND1 and GRAP2. May also interact with COPS5, RPLP0, SIRT6, SYF2 and TCF3.

9755:AK3
gene id: 9755:AK3
uniprot id: A0A2Y9F133
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
messages: Mitochondrion matrix
messages: Monomer.

9755:LOC102985773
gene id: 9755:LOC102985773
uniprot id: A0A2Y9SDI0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

9755:B3GNT8
gene id: 9755:B3GNT8
uniprot id: A0A2Y9FRK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9755:NLRP14
gene id: 9755:NLRP14
uniprot id: A0A2Y9EYP6
names: Similarity
messages: Belongs to the NLRP family.

9755:TNNT2
gene id: 9755:TNNT2
uniprot id: A0A455B5H9
names: Function
names: Similarity
messages: Belongs to the troponin T family.
messages: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

9755:SPTBN4
gene id: 9755:SPTBN4
uniprot id: A0A2Y9TBT4
names: Similarity
messages: Belongs to the spectrin family.

9755:SPTY2D1
gene id: 9755:SPTY2D1
uniprot id: A0A2Y9ELV8
uniprot id: A0A2Y9ENB7
names: Similarity
messages: Belongs to the SPT2 family.

9755:CDK6
gene id: 9755:CDK6
uniprot id: A0A2Y9TEJ3
names: Similarity
messages: Belongs to the protein kinase superfamily.

9755:RBM46
gene id: 9755:RBM46
uniprot id: A0A2Y9FE47
names: Subcellular Location Annotation
messages: Cytoplasm

9755:DIO1
gene id: 9755:DIO1
uniprot id: A0A2Y9FPU9
uniprot id: A0A2Y9SE00
names: Function
names: Similarity
messages: Belongs to the iodothyronine deiodinase family.
messages: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).

9755:COG8
gene id: 9755:COG8
uniprot id: A0A2Y9FRD3
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins.

9755:LOC102975307
gene id: 9755:LOC102975307
uniprot id: A0A2Y9FFF7
uniprot id: A0A455C6H8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

9755:EAF2
gene id: 9755:EAF2
uniprot id: A0A2Y9FGX3
names: Similarity
messages: Belongs to the EAF family.

9755:SLC10A4
gene id: 9755:SLC10A4
uniprot id: A0A2Y9F5M3
uniprot id: A0A455BU01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

9755:ROR1
gene id: 9755:ROR1
uniprot id: A0A2Y9FS02
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:KCNJ8
gene id: 9755:KCNJ8
uniprot id: A0A2Y9FCF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

9755:ASZ1
gene id: 9755:ASZ1
uniprot id: A0A2Y9F5D0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with DDX4, PIWIL1, RANBP9 and TDRD1.
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

9755:LOC112063998
gene id: 9755:LOC112063998
uniprot id: A0A2Y9SIQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

9755:SERPINI1
gene id: 9755:SERPINI1
uniprot id: A0A2Y9SP69
names: Similarity
messages: Belongs to the serpin family.

9755:OCSTAMP
gene id: 9755:OCSTAMP
uniprot id: A0A2Y9F5F9
names: Subcellular Location Annotation
messages: Membrane

9755:FBXL5
gene id: 9755:FBXL5
uniprot id: A0A2Y9S8Z9
uniprot id: A0A2Y9SHB3
uniprot id: A0A455BGS0
names: Subcellular Location Annotation
messages: perinuclear region

9755:KNG1
gene id: 9755:KNG1
uniprot id: A0A2Y9SRQ8
names: Subcellular Location Annotation
messages: extracellular space

9755:ATOSA
gene id: 9755:ATOSA
uniprot id: A0A2Y9F9X5
uniprot id: A0A455BP36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATOS family.
messages: Nucleus

9755:CUTA
gene id: 9755:CUTA
uniprot id: A0A2Y9FSV9
uniprot id: A0A2Y9FTP9
uniprot id: A0A455AFW3
names: Similarity
names: Subunit
messages: Belongs to the CutA family.
messages: Homotrimer.

9755:GPT2
gene id: 9755:GPT2
uniprot id: A0A455AC72
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

9755:PIK3CG
gene id: 9755:PIK3CG
uniprot id: A0A2Y9F6Y3
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

9755:LRP4
gene id: 9755:LRP4
uniprot id: A0A455AMH2
names: Caution
names: Similarity
messages: Belongs to the LDLR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:LOC102991986
gene id: 9755:LOC102991986
uniprot id: A0A2Y9SFW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC2 family.
messages: Cell projection
messages: Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC. Interacts with SHANK3; the interaction probably mediates the association of SHANK3 with the Arp2/3 complex.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton
messages: synaptosome

9755:TWF1
gene id: 9755:TWF1
uniprot id: A0A2Y9SMM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

9755:SMAD9
gene id: 9755:SMAD9
uniprot id: A0A2Y9SW90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

9755:SLC7A10
gene id: 9755:SLC7A10
uniprot id: A0A2Y9THW7
names: Subcellular Location Annotation
messages: Membrane

9755:SSR4
gene id: 9755:SSR4
uniprot id: A0A2Y9F2D1
uniprot id: A0A2Y9F382
uniprot id: A0A2Y9F3T1
uniprot id: A0A2Y9S564
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-delta family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

9755:CAMK1
gene id: 9755:CAMK1
uniprot id: A0A2Y9FHS0
names: Similarity
messages: Belongs to the protein kinase superfamily.

9755:FERMT1
gene id: 9755:FERMT1
uniprot id: A0A2Y9SSD1
uniprot id: A0A2Y9SU98
names: Similarity
messages: Belongs to the kindlin family.

9755:COPS7A
gene id: 9755:COPS7A
uniprot id: A0A2Y9EU43
uniprot id: A0A2Y9EUQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
messages: Cytoplasm
messages: Nucleus

9755:EIF4G3
gene id: 9755:EIF4G3
uniprot id: A0A2Y9SSG5
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4G family.

9755:TRAPPC3L
gene id: 9755:TRAPPC3L
uniprot id: A0A2Y9EV52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Homodimer.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: cis-Golgi network

9755:DMC1
gene id: 9755:DMC1
uniprot id: A0A2Y9F0U9
names: Similarity
messages: Belongs to the RecA family. DMC1 subfamily.

9755:SLC6A17
gene id: 9755:SLC6A17
uniprot id: A0A2Y9ER17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

9755:MFNG
gene id: 9755:MFNG
uniprot id: A0A2Y9EZ17
uniprot id: A0A455BBH9
uniprot id: A0A455BDX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9755:CNTNAP5
gene id: 9755:CNTNAP5
uniprot id: A0A2Y9RW51
names: Caution
names: Similarity
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:SBF1
gene id: 9755:SBF1
uniprot id: A0A2Y9T0A7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

9755:SLC4A7
gene id: 9755:SLC4A7
uniprot id: A0A2Y9S0X7
uniprot id: A0A2Y9S7S7
uniprot id: A0A2Y9S8Y4
uniprot id: A0A455AFG5
uniprot id: A0A455AGR9
uniprot id: A0A455AGS3
uniprot id: A0A455AHD7
uniprot id: A0A455ASX4
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane

9755:LOC112067148
gene id: 9755:LOC112067148
uniprot id: A0A2Y9S672
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Cell membrane
messages: Cleavage furrow
messages: Endosome membrane
messages: Midbody ring
messages: Recycling endosome membrane
messages: filopodium membrane
messages: ruffle

9755:PLK3
gene id: 9755:PLK3
uniprot id: A0A2Y9EX55
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

9755:LOC102996919
gene id: 9755:LOC102996919
uniprot id: A0A2Y9S880
names: Function
names: Similarity
messages: Belongs to the SAA family.
messages: Major acute phase reactant. Apolipoprotein of the HDL complex.

9755:LOC112065988
gene id: 9755:LOC112065988
uniprot id: A0A2Y9T602
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.

9755:SMOC1
gene id: 9755:SMOC1
uniprot id: A0A455C7M1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:LOC102995526
gene id: 9755:LOC102995526
uniprot id: A0A2Y9EQB5
uniprot id: A0A455B8M1
uniprot id: A0A455B8Z9
uniprot id: A0A455BB05
names: Similarity
messages: Belongs to the cytochrome P450 family.

9755:CPVL
gene id: 9755:CPVL
uniprot id: A0A2Y9TBA8
names: Similarity
messages: Belongs to the peptidase S10 family.

9755:BCLAF3
gene id: 9755:BCLAF3
uniprot id: A0A2Y9S0I4
uniprot id: A0A455ANU9
uniprot id: A0A455AQN9
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

9755:OAZ3
gene id: 9755:OAZ3
uniprot id: A0A2Y9D5Q5
uniprot id: A0A2Y9D5R4
names: Similarity
messages: Belongs to the ODC antizyme family.

9755:SGSM3
gene id: 9755:SGSM3
uniprot id: A0A2Y9F9H7
uniprot id: A0A455BBW3
uniprot id: A0A455BCI8
uniprot id: A0A455BCJ4
uniprot id: A0A455BCM5
uniprot id: A0A455BEX5
uniprot id: A0A455BRG4
uniprot id: A0A455BRG8
names: Similarity
messages: Belongs to the small G protein signaling modulator family.

9755:CACNA1G
gene id: 9755:CACNA1G
uniprot id: A0A2Y9T4I0
uniprot id: A0A2Y9T4J0
uniprot id: A0A2Y9T685
uniprot id: A0A2Y9T691
uniprot id: A0A2Y9T6A4
uniprot id: A0A2Y9T874
uniprot id: A0A2Y9T879
uniprot id: A0A2Y9TAF9
uniprot id: A0A2Y9TAG3
uniprot id: A0A2Y9TAG8
uniprot id: A0A2Y9TCQ7
uniprot id: A0A2Y9TCR1
uniprot id: A0A2Y9TCR7
uniprot id: A0A2Y9TCS8
uniprot id: A0A455C4Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite negative potentials, and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes.

9755:SPDEF
gene id: 9755:SPDEF
uniprot id: A0A2Y9EPL8
uniprot id: A0A455AHH5
uniprot id: A0A455ATR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9755:FUCA2
gene id: 9755:FUCA2
uniprot id: A0A2Y9F569
names: Function
names: Similarity
names: Subunit
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
messages: Belongs to the glycosyl hydrolase 29 family.
messages: Homotetramer.

9755:TET1
gene id: 9755:TET1
uniprot id: A0A2Y9FEK4
uniprot id: A0A2Y9FEN9
uniprot id: A0A2Y9TGF5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TET family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Chromosome
messages: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development.
messages: The zinc ions have a structural role.

9755:LOC102973132
gene id: 9755:LOC102973132
uniprot id: A0A2Y9TBH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:CTSH
gene id: 9755:CTSH
uniprot id: A0A2Y9T792
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

9755:DDC
gene id: 9755:DDC
uniprot id: A0A455BBK5
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

9755:FERMT2
gene id: 9755:FERMT2
uniprot id: A0A2Y9FG14
uniprot id: A0A455BRR6
uniprot id: A0A455BRS7
uniprot id: A0A455BRT1
uniprot id: A0A455BSG3
uniprot id: A0A455BSG8
uniprot id: A0A455BV48
uniprot id: A0A455C6X1
uniprot id: A0A455C6X6
names: Similarity
messages: Belongs to the kindlin family.

9755:PPFIA3
gene id: 9755:PPFIA3
uniprot id: A0A455ADQ2
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

9755:KCNB2
gene id: 9755:KCNB2
uniprot id: A0A2Y9F4G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.2/KCNB2 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: Perikaryon
messages: dendrite

9755:MPPED1
gene id: 9755:MPPED1
uniprot id: A0A2Y9ECI4
names: Similarity
messages: Belongs to the UPF0046 family.

9755:CENPC
gene id: 9755:CENPC
uniprot id: A0A2Y9ES59
uniprot id: A0A2Y9ESV4
uniprot id: A0A2Y9ETM8
uniprot id: A0A2Y9EU34
names: Similarity
messages: Belongs to the CENP-C/MIF2 family.

9755:GPR31
gene id: 9755:GPR31
uniprot id: A0A2Y9EUC9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9755:SKA3
gene id: 9755:SKA3
uniprot id: A0A2Y9T0U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKA3 family.
messages: kinetochore
messages: spindle

9755:LYVE1
gene id: 9755:LYVE1
uniprot id: A0A2Y9F738
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:RSAD1
gene id: 9755:RSAD1
uniprot id: A0A2Y9EKQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen-III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Mitochondrion

9755:KDM6A
gene id: 9755:KDM6A
uniprot id: A0A2Y9S0S5
uniprot id: A0A2Y9S0T8
uniprot id: A0A2Y9S4B7
uniprot id: A0A2Y9S4C2
uniprot id: A0A2Y9S7Q4
uniprot id: A0A2Y9S8T6
uniprot id: A0A455ANZ5
uniprot id: A0A455AQM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTX family.
messages: Nucleus

9755:XRN2
gene id: 9755:XRN2
uniprot id: A0A2Y9FJF9
names: Function
names: Similarity
messages: Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
messages: Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.

9755:NCBP2
gene id: 9755:NCBP2
uniprot id: A0A2Y9F5S9
uniprot id: A0A455BHV2
uniprot id: A0A455BX65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRM NCBP2 family.
messages: Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U snRNA and intronless mRNAs export from the nucleus. The CBC complex is essential for a pioneer round of mRNA translation, before steady state translation when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. The pioneer round of mRNA translation mediated by the CBC complex plays a central role in nonsense-mediated mRNA decay (NMD), NMD only taking place in mRNAs bound to the CBC complex, but not on eIF4E-bound mRNAs. The CBC complex enhances NMD in mRNAs containing at least one exon-junction complex (EJC), promoting the interaction between upf1 and upf2. The CBC complex is also involved in 'failsafe' NMD, which is independent of the EJC complex, while it does not participate in Staufen-mediated mRNA decay (SMD). During cell proliferation, the CBC complex is also involved in microRNAs (miRNAs) biogenesis via its interaction with srrt/ars2, thereby being required for miRNA-mediated RNA interference. The CBC complex also acts as a negative regulator of parn, thereby acting as an inhibitor of mRNA deadenylation. In the CBC complex, ncbp2/cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp1/cbp80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure. The conventional cap-binding complex with NCBP2 binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus.
messages: Component of the nuclear cap-binding complex (CBC), a heterodimer composed of ncbp1/cbp80 and ncbp2/cbp20 that interacts with m7GpppG-capped RNA.
messages: Nucleus

9755:MTIF2
gene id: 9755:MTIF2
uniprot id: A0A2Y9EQE6
uniprot id: A0A2Y9SEE7
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

9755:TPMT
gene id: 9755:TPMT
uniprot id: A0A2Y9F9T4
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Monomer.

9755:NIT1
gene id: 9755:NIT1
uniprot id: A0A2Y9F109
uniprot id: A0A2Y9S6T8
uniprot id: A0A455B7C1
uniprot id: A0A455B985
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

9755:PKDREJ
gene id: 9755:PKDREJ
uniprot id: A0A455BCP5
uniprot id: A0A455BRL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Membrane

9755:PIK3C3
gene id: 9755:PIK3C3
uniprot id: A0A2Y9SJ94
uniprot id: A0A455AH65
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

9755:COL4A1
gene id: 9755:COL4A1
uniprot id: A0A2Y9SJX4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

9755:HNMT
gene id: 9755:HNMT
uniprot id: A0A2Y9FBA9
names: Function
names: Subunit
messages: Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine.
messages: Monomer.

9755:TRDMT1
gene id: 9755:TRDMT1
uniprot id: A0A2Y9FAJ0
uniprot id: A0A2Y9S0P5
uniprot id: A0A2Y9S0P9
uniprot id: A0A455BUX5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

9755:SLC40A1
gene id: 9755:SLC40A1
uniprot id: A0A2Y9F4N4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lateral cell membrane
messages: May be involved in iron transport and iron homeostasis.
messages: Membrane

9755:LOC102990695
gene id: 9755:LOC102990695
uniprot id: A0A2Y9S5C1
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

9755:APOLD1
gene id: 9755:APOLD1
uniprot id: A0A455BDM6
names: Similarity
messages: Belongs to the apolipoprotein L family.

9755:PRKAR1B
gene id: 9755:PRKAR1B
uniprot id: A0A2Y9SNG4
uniprot id: A0A455CB38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

9755:LOC112064077
gene id: 9755:LOC112064077
uniprot id: A0A2Y9SGD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic AdoMetDC family.
messages: Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.
messages: Heterotetramer of two alpha and two beta chains.

9755:TMBIM6
gene id: 9755:TMBIM6
uniprot id: A0A2Y9SSA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

9755:SMARCA2
gene id: 9755:SMARCA2
uniprot id: A0A455BLT4
names: Similarity
messages: Belongs to the SNF2/RAD54 helicase family.

9755:DCK
gene id: 9755:DCK
uniprot id: A0A455BIG5
names: Similarity
messages: Belongs to the DCK/DGK family.

9755:LOC102988285
gene id: 9755:LOC102988285
uniprot id: A0A455C921
names: Subcellular Location Annotation
messages: Membrane

9755:UNC93B1
gene id: 9755:UNC93B1
uniprot id: A0A2Y9FPA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

9755:PRSS16
gene id: 9755:PRSS16
uniprot id: A0A2Y9FSC9
names: Similarity
messages: Belongs to the peptidase S28 family.

9755:TTR
gene id: 9755:TTR
uniprot id: A0A2Y9FU17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transthyretin family.
messages: Homotetramer. Dimer of dimers. In the homotetramer, subunits assemble around a central channel that can accommodate two ligand molecules. Interacts with RBP4.
messages: Secreted
messages: Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.

9755:PBX1
gene id: 9755:PBX1
uniprot id: A0A2Y9EGV9
uniprot id: A0A2Y9EH90
uniprot id: A0A455B6F1
uniprot id: A0A455B7A4
uniprot id: A0A455B965
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

9755:VARS2
gene id: 9755:VARS2
uniprot id: A0A455AGT2
uniprot id: A0A455AHE6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9755:MFAP5
gene id: 9755:MFAP5
uniprot id: A0A2Y9EH78
uniprot id: A0A2Y9EHX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MFAP family.
messages: extracellular matrix

9755:ZMPSTE24
gene id: 9755:ZMPSTE24
uniprot id: A0A2Y9SZS5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.

9755:LOC102996653
gene id: 9755:LOC102996653
uniprot id: A0A2Y9FT46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 6A family.
messages: Membrane
messages: Mitochondrion inner membrane

9755:PPP1R13B
gene id: 9755:PPP1R13B
uniprot id: A0A2Y9TF74
names: Subcellular Location Annotation
messages: Nucleus

9755:ZNF706
gene id: 9755:ZNF706
uniprot id: A0A2Y9TA68
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9755:NKX6-3
gene id: 9755:NKX6-3
uniprot id: A0A2Y9TG25
names: Subcellular Location Annotation
messages: Nucleus

9755:LOC102986070
gene id: 9755:LOC102986070
uniprot id: A0A2Y9FPM9
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9755:NADK
gene id: 9755:NADK
uniprot id: A0A2Y9SRD0
names: Similarity
messages: Belongs to the NAD kinase family.

9755:APRT
gene id: 9755:APRT
uniprot id: A0A2Y9SPZ6
uniprot id: A0A455ADP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm

9755:PGD
gene id: 9755:PGD
uniprot id: A0A2Y9SSY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

9755:CTC1
gene id: 9755:CTC1
uniprot id: A0A2Y9FM48
uniprot id: A0A2Y9FMP1
uniprot id: A0A455C143
uniprot id: A0A455C226
uniprot id: A0A455C5B5
uniprot id: A0A455CAQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTC1 family.
messages: Nucleus
messages: telomere

9755:RSBN1L
gene id: 9755:RSBN1L
uniprot id: A0A2Y9EH39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the round spermatid basic protein 1 family.
messages: Nucleus

9755:USP1
gene id: 9755:USP1
uniprot id: A0A2Y9EUE4
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

9755:ZNF18
gene id: 9755:ZNF18
uniprot id: A0A2Y9FDE8
uniprot id: A0A2Y9FDS2
names: Subcellular Location Annotation
messages: Nucleus

9755:TM2D3
gene id: 9755:TM2D3
uniprot id: A0A2Y9EZE6
uniprot id: A0A2Y9F1I0
names: Subcellular Location Annotation
messages: Membrane

9755:ACSL6
gene id: 9755:ACSL6
uniprot id: A0A455BJ71
uniprot id: A0A455BMB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.
messages: Endoplasmic reticulum membrane
messages: Mitochondrion outer membrane

9755:TRIM25
gene id: 9755:TRIM25
uniprot id: A0A2Y9FHI2
uniprot id: A0A455C3X7
names: Subcellular Location Annotation
messages: Cytoplasm

9755:FGD5
gene id: 9755:FGD5
uniprot id: A0A2Y9SVY9
uniprot id: A0A455ATG1
names: Subcellular Location Annotation
messages: cytoskeleton

9755:AQP1
gene id: 9755:AQP1
uniprot id: A0A2Y9FV45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

9755:FCHO2
gene id: 9755:FCHO2
uniprot id: A0A2Y9TGE5
uniprot id: A0A455BIW3
uniprot id: A0A455BJ42
uniprot id: A0A455BLM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FCHO family.
messages: clathrin-coated pit

9755:DUSP12
gene id: 9755:DUSP12
uniprot id: A0A2Y9FG43
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

9755:LOC102985897
gene id: 9755:LOC102985897
uniprot id: A0A2Y9ETV8
uniprot id: A0A455ANJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX15/CtaA family.
messages: Membrane

9755:ZDHHC15
gene id: 9755:ZDHHC15
uniprot id: A0A455APZ9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9755:CDH20
gene id: 9755:CDH20
uniprot id: A0A2Y9F375
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

9755:SEMA5B
gene id: 9755:SEMA5B
uniprot id: A0A2Y9EW26
uniprot id: A0A2Y9SK22
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:PRIM2
gene id: 9755:PRIM2
uniprot id: A0A2Y9SG39
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.

9755:LOC102996437
gene id: 9755:LOC102996437
uniprot id: A0A455AQE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9755:ELMO1
gene id: 9755:ELMO1
uniprot id: A0A2Y9TEW8
uniprot id: A0A455BAG8
uniprot id: A0A455BCL7
uniprot id: A0A455BP84
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

9755:TMEM121
gene id: 9755:TMEM121
uniprot id: A0A2Y9T8Z6
names: Similarity
messages: Belongs to the TMEM121 family.

9755:PDGFRA
gene id: 9755:PDGFRA
uniprot id: A0A2Y9F044
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Interacts with homodimeric PDGFA, PDGFB and PDGFC, and with heterodimers formed by PDGFA and PDGFB. Monomer in the absence of bound ligand.
messages: Membrane
messages: Present in an inactive conformation in the absence of bound ligand. Binding of PDGFA and/or PDGFB leads to dimerization and activation by autophosphorylation on tyrosine residues.
messages: Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.

9755:CCNI
gene id: 9755:CCNI
uniprot id: A0A2Y9FJJ2
uniprot id: A0A2Y9RX62
names: Similarity
messages: Belongs to the cyclin family.

9755:ADGRD1
gene id: 9755:ADGRD1
uniprot id: A0A455AHS7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:TRAP1
gene id: 9755:TRAP1
uniprot id: A0A455C2L8
names: Similarity
messages: Belongs to the heat shock protein 90 family.

9755:ANXA5
gene id: 9755:ANXA5
uniprot id: A0A2Y9SCJ8
uniprot id: A0A455BJI1
names: Domain
names: Function
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.

9755:HEATR1
gene id: 9755:HEATR1
uniprot id: A0A2Y9S6G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HEATR1/UTP10 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

9755:AUP1
gene id: 9755:AUP1
uniprot id: A0A2Y9ERF4
uniprot id: A0A2Y9ERT5
uniprot id: A0A2Y9ES51
uniprot id: A0A2Y9ETB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AUP1 family.
messages: Membrane

9755:LOC102974522
gene id: 9755:LOC102974522
uniprot id: A0A2Y9FB17
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

9755:MYO7B
gene id: 9755:MYO7B
uniprot id: A0A2Y9S3N9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

9755:SCMH1
gene id: 9755:SCMH1
uniprot id: A0A2Y9SS37
uniprot id: A0A455AXR2
uniprot id: A0A455AXR7
uniprot id: A0A455AY03
uniprot id: A0A455AY30
uniprot id: A0A455AYU9
uniprot id: A0A455AYW7
uniprot id: A0A455AYX2
uniprot id: A0A455AYX7
uniprot id: A0A455AYZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

9755:MKX
gene id: 9755:MKX
uniprot id: A0A2Y9S8M9
names: Subcellular Location Annotation
messages: Nucleus

9755:KIFBP
gene id: 9755:KIFBP
uniprot id: A0A2Y9FEE2
uniprot id: A0A2Y9FGI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KIF-binding protein family.
messages: cytoskeleton

9755:CENPE
gene id: 9755:CENPE
uniprot id: A0A2Y9F4A3
uniprot id: A0A2Y9F4E4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9755:GUCA2A
gene id: 9755:GUCA2A
uniprot id: A0A2Y9EKS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylin family.
messages: Secreted

9755:REXO2
gene id: 9755:REXO2
uniprot id: A0A2Y9ER99
names: Similarity
messages: Belongs to the oligoribonuclease family.

9755:VTI1A
gene id: 9755:VTI1A
uniprot id: A0A2Y9SFI8
uniprot id: A0A2Y9SIF2
uniprot id: A0A2Y9SLB9
uniprot id: A0A455AKN1
uniprot id: A0A455AYZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

9755:LOC102975917
gene id: 9755:LOC102975917
uniprot id: A0A2Y9S7J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.
messages: Homotrimer. Functions as a homotrimer binding the FSH hormone heterodimer composed of CGA and FSHB (By similarity). Interacts with ARRB2 (By similarity). Interacts with APPL2; interaction is independent of follicle stimulating hormone stimulation.
messages: Membrane

9755:ELF4
gene id: 9755:ELF4
uniprot id: A0A2Y9EHV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9755:INKA1
gene id: 9755:INKA1
uniprot id: A0A2Y9F311
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INKA family.
messages: Nucleus

9755:GNRHR
gene id: 9755:GNRHR
uniprot id: A0A2Y9ESV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system.

9755:PIAS1
gene id: 9755:PIAS1
uniprot id: A0A2Y9EHX7
uniprot id: A0A2Y9EJA2
names: Similarity
messages: Belongs to the PIAS family.

9755:CFAP91
gene id: 9755:CFAP91
uniprot id: A0A2Y9SBN4
uniprot id: A0A2Y9SJZ8
uniprot id: A0A2Y9SK03
names: Similarity
messages: Belongs to the CFAP91 family.

9755:LOC102984889
gene id: 9755:LOC102984889
uniprot id: A0A2Y9F8G9
names: Similarity
messages: Belongs to the Speedy/Ringo family.

9755:LOC102984042
gene id: 9755:LOC102984042
uniprot id: A0A2Y9F8S4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9755:LOC102988698
gene id: 9755:LOC102988698
uniprot id: A0A2Y9T5T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 10 family.
messages: Nucleus

9755:RIBC2
gene id: 9755:RIBC2
uniprot id: A0A2Y9FQU2
names: Similarity
messages: Belongs to the RIB43A family.

9755:NIPSNAP3A
gene id: 9755:NIPSNAP3A
uniprot id: A0A2Y9F6G2
names: Similarity
messages: Belongs to the NipSnap family.

9755:CCNE2
gene id: 9755:CCNE2
uniprot id: A0A2Y9F7K2
names: Similarity
messages: Belongs to the cyclin family.

9755:PRPS2
gene id: 9755:PRPS2
uniprot id: A0A2Y9FIJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family.
messages: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
messages: Homodimer. The active form is probably a hexamer composed of 3 homodimers.

9755:PHLDA2
gene id: 9755:PHLDA2
uniprot id: A0A2Y9THK0
names: Subcellular Location Annotation
messages: Cytoplasm

9755:LOC112067445
gene id: 9755:LOC112067445
uniprot id: A0A2Y9TE23
uniprot id: A0A455AEU9
names: Similarity
messages: Belongs to the CDI family.

9755:SLC7A1
gene id: 9755:SLC7A1
uniprot id: A0A2Y9SSI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

9755:DCBLD2
gene id: 9755:DCBLD2
uniprot id: A0A2Y9SAT4
uniprot id: A0A455C1S9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:GJB2
gene id: 9755:GJB2
uniprot id: A0A2Y9SW17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9755:ITPR2
gene id: 9755:ITPR2
uniprot id: A0A2Y9T9Z4
uniprot id: A0A455BD57
uniprot id: A0A455BDU4
uniprot id: A0A455BDU7
uniprot id: A0A455BG72
uniprot id: A0A455BST9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the InsP3 receptor family.
messages: Endoplasmic reticulum membrane
messages: Homotetramer.
messages: Membrane
messages: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
messages: The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.

9755:ALKAL1
gene id: 9755:ALKAL1
uniprot id: A0A2Y9T1Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALKAL family.
messages: Secreted

9755:LOC102976287
gene id: 9755:LOC102976287
uniprot id: A0A2Y9FIZ1
uniprot id: A0A2Y9SH11
names: Similarity
messages: Belongs to the MHC class II family.

9755:GPRASP2
gene id: 9755:GPRASP2
uniprot id: A0A2Y9S3T3
names: Similarity
messages: Belongs to the GPRASP family.

9755:RPS6KA3
gene id: 9755:RPS6KA3
uniprot id: A0A2Y9EJC3
uniprot id: A0A2Y9EK14
uniprot id: A0A455ARF7
uniprot id: A0A455B387
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

9755:LOC102988795
gene id: 9755:LOC102988795
uniprot id: A0A2Y9FRA6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:LOC102974751
gene id: 9755:LOC102974751
uniprot id: A0A455ABN6
names: Similarity
messages: Belongs to the Izumo family.

9755:SLAIN2
gene id: 9755:SLAIN2
uniprot id: A0A2Y9TBV9
uniprot id: A0A2Y9TFW0
uniprot id: A0A2Y9THI1
uniprot id: A0A455BID5
names: Similarity
messages: Belongs to the SLAIN motif-containing family.

9755:PAPSS2
gene id: 9755:PAPSS2
uniprot id: A0A2Y9FKH6
uniprot id: A0A2Y9FKU9
names: Similarity
messages: In the C-terminal section; belongs to the sulfate adenylyltransferase family.
messages: In the N-terminal section; belongs to the APS kinase family.

9755:ROCK2
gene id: 9755:ROCK2
uniprot id: A0A2Y9FQJ9
uniprot id: A0A455BYE7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by RHOA binding. Inhibited by Y-27632.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane
messages: Nucleus
messages: Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
messages: centrosome

9755:EIF4G2
gene id: 9755:EIF4G2
uniprot id: A0A455C865
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4G family.

9755:MTX2
gene id: 9755:MTX2
uniprot id: A0A2Y9EZH5
uniprot id: A0A2Y9EZU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

9755:DIPK1B
gene id: 9755:DIPK1B
uniprot id: A0A2Y9SWU6
uniprot id: A0A455BXI6
names: Similarity
messages: Belongs to the DIPK family.

9755:NME9
gene id: 9755:NME9
uniprot id: A0A2Y9ERH7
uniprot id: A0A455AJ19
uniprot id: A0A455AKW0
uniprot id: A0A455AL45
names: Similarity
messages: Belongs to the NDK family.

9755:ABHD2
gene id: 9755:ABHD2
uniprot id: A0A2Y9FDZ2
uniprot id: A0A455BSC2
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

9755:NTNG1
gene id: 9755:NTNG1
uniprot id: A0A2Y9SBF8
uniprot id: A0A455B7U3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:MTG2
gene id: 9755:MTG2
uniprot id: A0A2Y9EG38
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

9755:CDC42BPG
gene id: 9755:CDC42BPG
uniprot id: A0A2Y9TJ59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
messages: Cytoplasm

9755:TAP2
gene id: 9755:TAP2
uniprot id: A0A2Y9SFH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCB family. MHC peptide exporter (TC 3.A.1.209) subfamily.
messages: Membrane

9755:HMCN1
gene id: 9755:HMCN1
uniprot id: A0A2Y9TH90
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:CCR8
gene id: 9755:CCR8
uniprot id: A0A2Y9FJ43
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9755:ZNF280D
gene id: 9755:ZNF280D
uniprot id: A0A2Y9T0S1
uniprot id: A0A2Y9T6T2
uniprot id: A0A2Y9T6T8
uniprot id: A0A2Y9T8V7
uniprot id: A0A455BT52
uniprot id: A0A455BWI6
names: Function
names: Subcellular Location Annotation
messages: May function as a transcription factor.
messages: Nucleus

9755:MAP4K3
gene id: 9755:MAP4K3
uniprot id: A0A2Y9S8E6
uniprot id: A0A2Y9SBM1
uniprot id: A0A2Y9SEK0
uniprot id: A0A455BU95
uniprot id: A0A455BXQ9
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

9755:CHRNA5
gene id: 9755:CHRNA5
uniprot id: A0A2Y9FJ27
uniprot id: A0A455BT29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9755:MMP1
gene id: 9755:MMP1
uniprot id: A0A2Y9S4J4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

9755:BEX4
gene id: 9755:BEX4
uniprot id: A0A2Y9FA84
names: Similarity
messages: Belongs to the BEX family.

9755:JRK
gene id: 9755:JRK
uniprot id: A0A455CBD5
names: Subcellular Location Annotation
messages: Nucleus

9755:PHACTR1
gene id: 9755:PHACTR1
uniprot id: A0A455AGR4
uniprot id: A0A455AHD1
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

9755:AMBN
gene id: 9755:AMBN
uniprot id: A0A2Y9FAU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ameloblastin family.
messages: Involved in the mineralization and structural organization of enamel.
messages: extracellular matrix

9755:PABIR3
gene id: 9755:PABIR3
uniprot id: A0A455AN91
names: Similarity
messages: Belongs to the FAM122 family.

9755:P4HA2
gene id: 9755:P4HA2
uniprot id: A0A2Y9SJC3
uniprot id: A0A2Y9SJW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

9755:LOC102980036
gene id: 9755:LOC102980036
uniprot id: A0A2Y9EKW7
uniprot id: A0A2Y9ELR8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:LOC102979350
gene id: 9755:LOC102979350
uniprot id: A0A2Y9EEA0
names: Similarity
messages: Belongs to the TMEM14 family.

9755:RPA1
gene id: 9755:RPA1
uniprot id: A0A2Y9FHY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
messages: Belongs to the replication factor A protein 1 family.
messages: Component of the heterotrimeric canonical replication protein A complex (RPA).
messages: PML body

9755:VPS54
gene id: 9755:VPS54
uniprot id: A0A2Y9EZ59
uniprot id: A0A2Y9EZR2
uniprot id: A0A2Y9F190
uniprot id: A0A455BVD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS54 family.
messages: trans-Golgi network

9755:LOC114484271
gene id: 9755:LOC114484271
uniprot id: A0A2Y9F5G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9755:LOC102995325
gene id: 9755:LOC102995325
uniprot id: A0A2Y9FIH8
names: Similarity
messages: Belongs to the SMEK family.

9755:GATM
gene id: 9755:GATM
uniprot id: A0A2Y9F7P7
uniprot id: A0A2Y9F999
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the amidinotransferase family.
messages: Homodimer.
messages: Mitochondrion inner membrane
messages: Transamidinase that catalyzes the transfer of the amidino group of L-arginine onto the amino moiety of acceptor metabolites such as glycine, beta-alanine, gamma-aminobutyric acid (GABA) and taurine yielding the corresponding guanidine derivatives. Catalyzes the rate-limiting step of creatine biosynthesis, namely the transfer of the amidino group from L-arginine to glycine to generate guanidinoacetate, which is then methylated by GAMT to form creatine. Provides creatine as a source for ATP generation in tissues with high energy demands, in particular skeletal muscle, heart and brain.

9755:MTRF1L
gene id: 9755:MTRF1L
uniprot id: A0A2Y9F3F9
uniprot id: A0A455BNT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

9755:XKRX
gene id: 9755:XKRX
uniprot id: A0A2Y9EXI1
uniprot id: A0A455AMV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

9755:MS4A13
gene id: 9755:MS4A13
uniprot id: A0A2Y9TG66
names: Similarity
messages: Belongs to the MS4A family.

9755:NAMPT
gene id: 9755:NAMPT
uniprot id: A0A2Y9RZG2
uniprot id: A0A455BQ46
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAPRTase family.
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Secreted

9755:TRMT61A
gene id: 9755:TRMT61A
uniprot id: A0A2Y9EDT0
uniprot id: A0A2Y9EED1
uniprot id: A0A2Y9EFI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
messages: Nucleus

9755:LOC102990403
gene id: 9755:LOC102990403
uniprot id: A0A2Y9T508
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9755:LOC102979979
gene id: 9755:LOC102979979
uniprot id: A0A455BXH5
names: Function
names: Similarity
messages: Belongs to the phage and mitochondrial RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

9755:MFSD6L
gene id: 9755:MFSD6L
uniprot id: A0A2Y9FY32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. MFSD6 family.
messages: Membrane

9755:TBX15
gene id: 9755:TBX15
uniprot id: A0A2Y9FI70
uniprot id: A0A455BLJ4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9755:IL1RAP
gene id: 9755:IL1RAP
uniprot id: A0A2Y9EIL8
uniprot id: A0A455BWB7
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

9755:CSPG4
gene id: 9755:CSPG4
uniprot id: A0A2Y9FAV8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:ST3GAL5
gene id: 9755:ST3GAL5
uniprot id: A0A455BY31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9755:ADAM2
gene id: 9755:ADAM2
uniprot id: A0A455ALD8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:FGF2
gene id: 9755:FGF2
uniprot id: A0A2Y9F7B8
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9755:SF3B3
gene id: 9755:SF3B3
uniprot id: A0A2Y9EJ37
names: Subcellular Location Annotation
messages: Nucleus

9755:CCHCR1
gene id: 9755:CCHCR1
uniprot id: A0A2Y9EP58
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be a regulator of keratinocyte proliferation or differentiation.
messages: Nucleus

9755:ADCY1
gene id: 9755:ADCY1
uniprot id: A0A2Y9EVI5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

9755:LOXHD1
gene id: 9755:LOXHD1
uniprot id: A0A455AJ39
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:ALG8
gene id: 9755:ALG8
uniprot id: A0A2Y9FGJ7
uniprot id: A0A2Y9FIB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:LOC102994410
gene id: 9755:LOC102994410
uniprot id: A0A455CA55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

9755:MFGE8
gene id: 9755:MFGE8
uniprot id: A0A2Y9F4V5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:LOC102988861
gene id: 9755:LOC102988861
uniprot id: A0A2Y9FH79
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

9755:POU1F1
gene id: 9755:POU1F1
uniprot id: A0A2Y9EJ39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

9755:RRAGC
gene id: 9755:RRAGC
uniprot id: A0A2Y9ESV3
uniprot id: A0A455B050
uniprot id: A0A455BCZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

9755:INSRR
gene id: 9755:INSRR
uniprot id: A0A2Y9EX12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

9755:LOC102985865
gene id: 9755:LOC102985865
uniprot id: A0A455APB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

9755:SLCO6A1
gene id: 9755:SLCO6A1
uniprot id: A0A2Y9SG58
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:SH3GL3
gene id: 9755:SH3GL3
uniprot id: A0A455BS31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Membrane

9755:VAPA
gene id: 9755:VAPA
uniprot id: A0A2Y9SCZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:PARD3
gene id: 9755:PARD3
uniprot id: A0A2Y9T3F0
uniprot id: A0A2Y9T3G5
uniprot id: A0A2Y9T5B3
uniprot id: A0A2Y9T5B6
uniprot id: A0A2Y9T5C1
uniprot id: A0A2Y9T5C6
uniprot id: A0A2Y9T7D1
uniprot id: A0A2Y9T7D6
uniprot id: A0A2Y9T9K5
uniprot id: A0A2Y9T9K9
uniprot id: A0A2Y9T9L5
uniprot id: A0A2Y9T9M1
uniprot id: A0A2Y9TBU6
uniprot id: A0A2Y9TBV0
uniprot id: A0A2Y9TBV5
uniprot id: A0A455BQX4
uniprot id: A0A455BQX9
uniprot id: A0A455BQY9
uniprot id: A0A455BQZ4
uniprot id: A0A455BRN6
uniprot id: A0A455BUA1
uniprot id: A0A455BUA7
uniprot id: A0A455C633
uniprot id: A0A455C639
uniprot id: A0A455C643
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR3 family.
messages: Cell junction
messages: Endomembrane system

9755:CHST11
gene id: 9755:CHST11
uniprot id: A0A455BCG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

9755:FAM83A
gene id: 9755:FAM83A
uniprot id: A0A2Y9FNQ8
names: Similarity
messages: Belongs to the FAM83 family.

9755:NIF3L1
gene id: 9755:NIF3L1
uniprot id: A0A2Y9ESR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
messages: Cytoplasm
messages: Homodimer. Interacts with COPS2. Interacts with THOC7.
messages: May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation.
messages: Nucleus

9755:PARP16
gene id: 9755:PARP16
uniprot id: A0A2Y9EM40
uniprot id: A0A2Y9EM91
uniprot id: A0A2Y9EMM7
uniprot id: A0A2Y9ENQ8
uniprot id: A0A2Y9T177
uniprot id: A0A2Y9T4Z5
uniprot id: A0A455C5T8
names: Similarity
messages: Belongs to the ARTD/PARP family.

9755:CKMT2
gene id: 9755:CKMT2
uniprot id: A5LH93
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

9755:FAH
gene id: 9755:FAH
uniprot id: A0A2Y9FLP7
uniprot id: A0A455BR62
uniprot id: A0A455BRV6
uniprot id: A0A455BUH7
uniprot id: A0A455C6A1
names: Similarity
messages: Belongs to the FAH family.

9755:RXRA
gene id: 9755:RXRA
uniprot id: A0A455BW26
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

9755:KCNK5
gene id: 9755:KCNK5
uniprot id: A0A2Y9FV07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

9755:LOC102981073
gene id: 9755:LOC102981073
uniprot id: A0A2Y9SF48
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9755:DCTN6
gene id: 9755:DCTN6
uniprot id: A0A2Y9F980
uniprot id: A0A455B027
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.
messages: Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.
messages: cytoskeleton

9755:LOC102974647
gene id: 9755:LOC102974647
uniprot id: A0A2Y9TI36
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

9755:KDM4C
gene id: 9755:KDM4C
uniprot id: A0A2Y9SV33
uniprot id: A0A455BLL1
uniprot id: A0A455BM06
uniprot id: A0A455BPK5
uniprot id: A0A455C1C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM3 histone demethylase family.
messages: Nucleus

9755:GAL3ST1
gene id: 9755:GAL3ST1
uniprot id: A0A2Y9FQN4
uniprot id: A0A2Y9FQV5
uniprot id: A0A2Y9SDV9
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

9755:DLX2
gene id: 9755:DLX2
uniprot id: A0A2Y9SNJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

9755:LOC102979050
gene id: 9755:LOC102979050
uniprot id: A0A2Y9EX98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCRB/QCR7 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Mitochondrion inner membrane

9755:LOC102975285
gene id: 9755:LOC102975285
uniprot id: A0A2Y9SUK7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9755:GPRASP3
gene id: 9755:GPRASP3
uniprot id: A0A2Y9FF91
names: Similarity
messages: Belongs to the GPRASP family.

9755:TPR
gene id: 9755:TPR
uniprot id: A0A2Y9FBA3
uniprot id: A0A455B8D6
names: Similarity
messages: Belongs to the TPR family.

9755:SSTR1
gene id: 9755:SSTR1
uniprot id: A0A2Y9FK33
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9755:SSBP1
gene id: 9755:SSBP1
uniprot id: A0A2Y9T6E7
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

9755:CAPN11
gene id: 9755:CAPN11
uniprot id: A0A2Y9ESX5
names: Similarity
messages: Belongs to the peptidase C2 family.

9755:PSMD1
gene id: 9755:PSMD1
uniprot id: A0A2Y9SUQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S1 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

9755:LOC102988767
gene id: 9755:LOC102988767
uniprot id: A0A2Y9FIJ1
names: Similarity
messages: Belongs to the CLCR family.

9755:CHRNA3
gene id: 9755:CHRNA3
uniprot id: A0A2Y9T165
uniprot id: A0A2Y9T4Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9755:KIF20A
gene id: 9755:KIF20A
uniprot id: A0A2Y9F2X6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9755:VIL1
gene id: 9755:VIL1
uniprot id: A0A455ANJ1
names: Similarity
messages: Belongs to the villin/gelsolin family.

9755:SPIC
gene id: 9755:SPIC
uniprot id: A0A2Y9F9F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9755:SCN8A
gene id: 9755:SCN8A
uniprot id: A0A2Y9EF45
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

9755:LOC102992493
gene id: 9755:LOC102992493
uniprot id: A0A2Y9F230
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:LOC102996067
gene id: 9755:LOC102996067
uniprot id: A0A2Y9SEI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-5A synthase family.
messages: Cytoplasm

9755:PIK3CB
gene id: 9755:PIK3CB
uniprot id: A0A2Y9TH96
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

9755:DPYSL2
gene id: 9755:DPYSL2
uniprot id: A0A2Y9FNT2
uniprot id: A0A2Y9FP88
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

9755:HIGD1A
gene id: 9755:HIGD1A
uniprot id: A0A2Y9ERI4
uniprot id: A0A2Y9T1C8
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

9755:CPNE4
gene id: 9755:CPNE4
uniprot id: A0A2Y9S0D5
names: Similarity
messages: Belongs to the copine family.

9755:EGFL6
gene id: 9755:EGFL6
uniprot id: A0A2Y9RY61
names: Caution
names: Similarity
messages: Belongs to the nephronectin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:KCNA3
gene id: 9755:KCNA3
uniprot id: A0A2Y9SEE1
names: Subcellular Location Annotation
messages: Membrane

9755:UCN2
gene id: 9755:UCN2
uniprot id: A0A2Y9FUS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Binds with high affinity to CRF receptors 2-alpha and 2-beta.
messages: Secreted
messages: Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.

9755:CDK3
gene id: 9755:CDK3
uniprot id: A0A455C365
names: Similarity
messages: Belongs to the protein kinase superfamily.

9755:ODF2L
gene id: 9755:ODF2L
uniprot id: A0A2Y9F6F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

9755:UCKL1
gene id: 9755:UCKL1
uniprot id: A0A2Y9T429
uniprot id: A0A455BZN1
uniprot id: A0A455BZN4
uniprot id: A0A455BZN5
uniprot id: A0A455CAE3
uniprot id: A0A455CAE4
names: Similarity
messages: Belongs to the uridine kinase family.

9755:SVIL
gene id: 9755:SVIL
uniprot id: A0A455BRY2
uniprot id: A0A455BRZ0
uniprot id: A0A455BSM9
uniprot id: A0A455BSN2
uniprot id: A0A455BSN8
uniprot id: A0A455BVB1
uniprot id: A0A455BVC3
uniprot id: A0A455C735
uniprot id: A0A455C740
names: Similarity
messages: Belongs to the villin/gelsolin family.

9755:SMC1A
gene id: 9755:SMC1A
uniprot id: A0A2Y9FH67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Chromosome
messages: Nucleus

9755:CCNG2
gene id: 9755:CCNG2
uniprot id: A0A2Y9FLT1
uniprot id: A0A455BV92
names: Similarity
messages: Belongs to the cyclin family.

9755:LOC114483879
gene id: 9755:LOC114483879
uniprot id: A0A455AJS9
uniprot id: A0A455AW84
names: Similarity
messages: Belongs to the G-alpha family. G(s) subfamily.

9755:NR1D2
gene id: 9755:NR1D2
uniprot id: A0A2Y9S4V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9755:DLGAP5
gene id: 9755:DLGAP5
uniprot id: A0A2Y9F6I1
uniprot id: A0A2Y9F6T2
uniprot id: A0A2Y9F8D6
names: Similarity
messages: Belongs to the SAPAP family.

9755:RBFOX2
gene id: 9755:RBFOX2
uniprot id: A0A2Y9EHA4
uniprot id: A0A2Y9T0C3
uniprot id: A0A455BCG8
uniprot id: A0A455BCH2
uniprot id: A0A455BEQ4
uniprot id: A0A455BEQ9
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

9755:DOCK8
gene id: 9755:DOCK8
uniprot id: A0A2Y9FRL0
uniprot id: A0A2Y9SWE0
names: Similarity
messages: Belongs to the DOCK family.

9755:LOC114484106
gene id: 9755:LOC114484106
uniprot id: A0A455ACR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

9755:TMSB10
gene id: 9755:TMSB10
uniprot id: A0A2Y9T7Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

9755:SERINC4
gene id: 9755:SERINC4
uniprot id: A0A2Y9SB44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

9755:SLC10A5
gene id: 9755:SLC10A5
uniprot id: A0A2Y9FK34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

9755:ERLEC1
gene id: 9755:ERLEC1
uniprot id: A0A2Y9S6T2
uniprot id: A0A2Y9SAI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OS-9 family.
messages: Endoplasmic reticulum lumen
messages: Lectin involved in the quality control of the secretory pathway. As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, targets misfolded endoplasmic reticulum lumenal glycoproteins for degradation.

9755:SNRPN
gene id: 9755:SNRPN
uniprot id: A0A2Y9FFY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP SmB/SmN family.
messages: Nucleus

9755:PPP2CA
gene id: 9755:PPP2CA
uniprot id: A0A2Y9F2F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family.
messages: Cytoplasm

9755:FMNL1
gene id: 9755:FMNL1
uniprot id: A0A2Y9T8S0
names: Similarity
messages: Belongs to the formin homology family.

9755:WNT2B
gene id: 9755:WNT2B
uniprot id: A0A2Y9F3C9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9755:CLDN19
gene id: 9755:CLDN19
uniprot id: A0A2Y9EVZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9755:LOC102974005
gene id: 9755:LOC102974005
uniprot id: A0A2Y9TFS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

9755:LAMA4
gene id: 9755:LAMA4
uniprot id: A0A2Y9RXU1
uniprot id: A0A2Y9RYG7
uniprot id: A0A2Y9S5B1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

9755:C7H4orf48
gene id: 9755:C7H4orf48
uniprot id: A0A2Y9SF89
names: Subcellular Location Annotation
messages: Secreted

9755:TRPV3
gene id: 9755:TRPV3
uniprot id: A0A2Y9FMM1
names: Subcellular Location Annotation
messages: Membrane

9755:POLR1D
gene id: 9755:POLR1D
uniprot id: A0A2Y9SUC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Component of the RNA polymerase I (Pol I) and RNA polymerase III (Pol III) complexes consisting of at least 13 and 17 subunits, respectively.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively.

9755:B2M
gene id: 9755:B2M
uniprot id: A0A2Y9FHQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-2-microglobulin family.
messages: Secreted

9755:SCUBE3
gene id: 9755:SCUBE3
uniprot id: A0A2Y9EVN7
uniprot id: A0A2Y9SG16
uniprot id: A0A2Y9SMQ5
uniprot id: A0A2Y9SPH5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9755:MRPS6
gene id: 9755:MRPS6
uniprot id: A0A455BHJ4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.

9755:OSTC
gene id: 9755:OSTC
uniprot id: A0A2Y9FFJ1
uniprot id: A0A2Y9FHD9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OSTC family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Specific component of the STT3A-containing form of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. May be involved in N-glycosylation of APP (amyloid-beta precursor protein). Can modulate gamma-secretase cleavage of APP by enhancing endoprotelysis of PSEN1.

9755:HARS2
gene id: 9755:HARS2
uniprot id: A0A2Y9ES32
uniprot id: A0A2Y9EU02
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

9755:PDPR
gene id: 9755:PDPR
uniprot id: A0A2Y9EHS5
names: Similarity
messages: Belongs to the GcvT family.

9755:LOC102986917
gene id: 9755:LOC102986917
uniprot id: A0A2Y9ENW2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:SLC2A9
gene id: 9755:SLC2A9
uniprot id: A0A2Y9S9F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane

9755:TUBGCP3
gene id: 9755:TUBGCP3
uniprot id: A0A2Y9SA83
uniprot id: A0A2Y9SBN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

9755:GALNT13
gene id: 9755:GALNT13
uniprot id: A0A2Y9SNY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9755:TIMM13
gene id: 9755:TIMM13
uniprot id: A0A2Y9ESS8
uniprot id: A0A455CBM9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

9755:EPB41
gene id: 9755:EPB41
uniprot id: A0A455B253
uniprot id: A0A455B2H5
uniprot id: A0A455B2I0
uniprot id: A0A455B2K9
uniprot id: A0A455B2L8
uniprot id: A0A455B362
uniprot id: A0A455B4L4
uniprot id: A0A455BG92
names: Subcellular Location Annotation
messages: Nucleus
messages: cell cortex
messages: cytoskeleton

9755:DENR
gene id: 9755:DENR
uniprot id: A0A2Y9F900
names: Similarity
messages: Belongs to the DENR family.

9755:CCR7
gene id: 9755:CCR7
uniprot id: A0A2Y9F247
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9755:CEP170
gene id: 9755:CEP170
uniprot id: A0A2Y9TEU3
uniprot id: A0A2Y9TGX5
uniprot id: A0A2Y9TIK1
uniprot id: A0A2Y9TIK4
uniprot id: A0A2Y9TIK6
uniprot id: A0A2Y9TJZ0
names: Similarity
messages: Belongs to the CEP170 family.

9755:LOC112062683
gene id: 9755:LOC112062683
uniprot id: A0A2Y9S7Y9
names: Subcellular Location Annotation
messages: growth cone
messages: lamellipodium

9755:FAM13C
gene id: 9755:FAM13C
uniprot id: A0A2Y9RY13
uniprot id: A0A2Y9RYM3
uniprot id: A0A455AMM7
uniprot id: A0A455B1D4
names: Similarity
messages: Belongs to the FAM13 family.

9755:CPA4
gene id: 9755:CPA4
uniprot id: A0A2Y9TDZ2
uniprot id: A0A455BA38
names: Similarity
messages: Belongs to the peptidase M14 family.

9755:KPNA4
gene id: 9755:KPNA4
uniprot id: A0A2Y9SU99
names: Function
names: Similarity
messages: Belongs to the importin alpha family.
messages: Functions in nuclear protein import.

9755:A2ML1
gene id: 9755:A2ML1
uniprot id: A0A2Y9EHL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

9755:LOC102992419
gene id: 9755:LOC102992419
uniprot id: A0A2Y9F8A0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9755:SELENOS
gene id: 9755:SELENOS
uniprot id: A0A2Y9FET6
uniprot id: A0A2Y9RWP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenoprotein S family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination.
messages: Membrane

9755:RLN1
gene id: 9755:RLN1
uniprot id: A0A2Y9FL98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

9755:LOC112061977
gene id: 9755:LOC112061977
uniprot id: A0A2Y9RXD9
names: Similarity
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.

9755:GOLM1
gene id: 9755:GOLM1
uniprot id: A0A2Y9TCK1
uniprot id: A0A455BLQ5
uniprot id: A0A455C1T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLM family.
messages: Membrane

9755:PAF1
gene id: 9755:PAF1
uniprot id: A0A2Y9F3T7
uniprot id: A0A2Y9F5K1
names: Similarity
messages: Belongs to the PAF1 family.

9755:LOC102978667
gene id: 9755:LOC102978667
uniprot id: A0A2Y9FT95
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9755:GNA14
gene id: 9755:GNA14
uniprot id: A0A2Y9SWT0
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

9755:CTSK
gene id: 9755:CTSK
uniprot id: A0A2Y9FTT0
uniprot id: A0A2Y9FWT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

9755:LOC112066141
gene id: 9755:LOC112066141
uniprot id: A0A455B4Z5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

9755:GPR155
gene id: 9755:GPR155
uniprot id: A0A2Y9F2A0
uniprot id: A0A2Y9F2E6
uniprot id: A0A455AF48
uniprot id: A0A455AGW5
names: Subcellular Location Annotation
messages: Membrane

9755:ZNF287
gene id: 9755:ZNF287
uniprot id: A0A2Y9FLB8
names: Subcellular Location Annotation
messages: Nucleus

9755:PCYOX1L
gene id: 9755:PCYOX1L
uniprot id: A0A2Y9FUA8
names: Similarity
messages: Belongs to the prenylcysteine oxidase family.

9755:KEF67 p09
gene id: 9755:KEF67_p09
uniprot id: Q9MET2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase protein 8 family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. Component of an ATP synthase complex composed of ATP5PB, ATP5MC1, ATP5F1E, ATP5PD, ATP5ME, ATP5PF, ATP5MF, MT-ATP6, MT-ATP8, ATP5F1A, ATP5F1B, ATP5F1D, ATP5F1C, ATP5PO, ATP5MG, ATP5MK and ATP5MJ (By similarity). Interacts with PRICKLE3 (By similarity).
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane (By similarity).
messages: Mitochondrion membrane

9755:PTGS1
gene id: 9755:PTGS1
uniprot id: A0A2Y9T2F1
uniprot id: A0A455BKG0
names: Caution
names: Similarity
messages: Belongs to the prostaglandin G/H synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:ALPI
gene id: 9755:ALPI
uniprot id: A0A2Y9SP20
uniprot id: A0A455APJ5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

9755:DUSP29
gene id: 9755:DUSP29
uniprot id: A0A2Y9EHW2
uniprot id: A0A455AKQ2
uniprot id: A0A455AM87
uniprot id: A0A455AZ25
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

9755:METTL14
gene id: 9755:METTL14
uniprot id: A0A2Y9S987
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MT-A70-like family.
messages: Heterodimer; heterodimerizes with METTL3 to form an antiparallel heterodimer that constitutes an active methyltransferase.
messages: Nucleus
messages: The METTL3-METTL14 heterodimer forms a N6-methyltransferase complex that methylates adenosine residues at the N(6) position of some mRNAs and regulates the circadian clock, differentiation of embryonic stem cells and cortical neurogenesis. In the heterodimer formed with METTL3, METTL14 constitutes the RNA-binding scaffold that recognizes the substrate rather than the catalytic core. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in mRNA stability and processing. M6A acts as a key regulator of mRNA stability by promoting mRNA destabilization and degradation. In embryonic stem cells (ESCs), m6A methylation of mRNAs encoding key naive pluripotency-promoting transcripts results in transcript destabilization. M6A regulates spermatogonial differentiation and meiosis and is essential for male fertility and spermatogenesis. M6A also regulates cortical neurogenesis: m6A methylation of transcripts related to transcription factors, neural stem cells, the cell cycle and neuronal differentiation during brain development promotes their destabilization and decay, promoting differentiation of radial glial cells.

9755:CHD1L
gene id: 9755:CHD1L
uniprot id: A0A2Y9FBZ5
uniprot id: A0A2Y9FE22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

9755:TRAM1
gene id: 9755:TRAM1
uniprot id: A0A2Y9FR64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

9755:CXCR6
gene id: 9755:CXCR6
uniprot id: A0A455AIM0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9755:THTPA
gene id: 9755:THTPA
uniprot id: A0A2Y9FTF3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Hydrolase highly specific for thiamine triphosphate (ThTP).
messages: Monomer.

9755:NEFH
gene id: 9755:NEFH
uniprot id: A0A455AHZ9
names: Similarity
messages: Belongs to the intermediate filament family.

9755:GNG2
gene id: 9755:GNG2
uniprot id: A0A2Y9SCS4
uniprot id: A0A455BV34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

9755:GRIN2A
gene id: 9755:GRIN2A
uniprot id: A0A455C0S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

9755:JAG1
gene id: 9755:JAG1
uniprot id: A0A2Y9SNZ9
uniprot id: A0A455BZH9
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

9755:FBN3
gene id: 9755:FBN3
uniprot id: A0A2Y9TG33
uniprot id: A0A2Y9TKU0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fibrillin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9755:NGRN
gene id: 9755:NGRN
uniprot id: A0A2Y9EU87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the neugrin family.
messages: Forms a regulatory protein-RNA complex, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mt-rRNA. Interacts with 16S mt-rRNA; this interaction is direct.
messages: Mitochondrion membrane
messages: Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.

9755:CSN2
gene id: 9755:CSN2
uniprot id: A0A2Y9FGQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-casein family.
messages: Important role in determination of the surface properties of the casein micelles.
messages: Secreted

9755:CPSF6
gene id: 9755:CPSF6
uniprot id: A0A2Y9SIV5
uniprot id: A0A2Y9SJF3
uniprot id: A0A2Y9SM83
uniprot id: A0A2Y9SQ84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CPSF6/7 family.
messages: Nucleus

9755:PPP1CB
gene id: 9755:PPP1CB
uniprot id: A0A2Y9SAP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: nucleolus
messages: nucleoplasm

9755:DBH
gene id: 9755:DBH
uniprot id: A0A2Y9EYV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the copper type II ascorbate-dependent monooxygenase family.
messages: Conversion of dopamine to noradrenaline.
messages: Homotetramer; composed of two disulfide-linked dimers.
messages: chromaffin granule lumen
messages: chromaffin granule membrane
messages: secretory vesicle lumen
messages: secretory vesicle membrane

9755:DNMT1
gene id: 9755:DNMT1
uniprot id: A0A2Y9EM37
uniprot id: A0A2Y9TG09
uniprot id: A0A2Y9THV2
uniprot id: A0A2Y9TJE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

9755:LOC102981548
gene id: 9755:LOC102981548
uniprot id: A0A2Y9SR91
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:PHTF1
gene id: 9755:PHTF1
uniprot id: A0A2Y9EUB9
uniprot id: A0A2Y9EUY5
uniprot id: A0A455B7M1
uniprot id: A0A455B9Z4
names: Subcellular Location Annotation
messages: Membrane

9755:EYA4
gene id: 9755:EYA4
uniprot id: A0A455BMM4
uniprot id: A0A455BMN0
uniprot id: A0A455BMN5
uniprot id: A0A455BMU4
uniprot id: A0A455BMU9
uniprot id: A0A455BMV4
uniprot id: A0A455BMV8
uniprot id: A0A455BNC0
uniprot id: A0A455BNC5
uniprot id: A0A455BNC9
uniprot id: A0A455BQX5
uniprot id: A0A455BQY0
uniprot id: A0A455BQY2
uniprot id: A0A455C2S2
uniprot id: A0A455C2S7
uniprot id: A0A455C2T2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

9755:BEND6
gene id: 9755:BEND6
uniprot id: A0A2Y9FC04
names: Subcellular Location Annotation
messages: Nucleus

9755:NAA30
gene id: 9755:NAA30
uniprot id: A0A2Y9S5V6
names: Similarity
messages: Belongs to the acetyltransferase family. MAK3 subfamily.

9755:EIF3G
gene id: 9755:EIF3G
uniprot id: A0A2Y9ELY6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit G family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of FRAP1 and RAPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts (via C-terminus) with AIFM1 (via N-terminus).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. This subunit can bind 18S rRNA.
messages: perinuclear region

9755:PKIB
gene id: 9755:PKIB
uniprot id: A0A2Y9SPN9
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

9755:DHTKD1
gene id: 9755:DHTKD1
uniprot id: A0A2Y9FTM0
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

9755:IFNGR1
gene id: 9755:IFNGR1
uniprot id: A0A2Y9FX73
names: Similarity
messages: Belongs to the type II cytokine receptor family.

9755:PTEN
gene id: 9755:PTEN
uniprot id: A0A2Y9FKD1
uniprot id: A0A2Y9FLR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3,4,5)P3 > PtdIns(3,4)P2 > PtdIns3P > Ins(1,3,4,5)P4.
messages: Belongs to the PTEN phosphatase protein family.
messages: Cytoplasm
messages: Nucleus
messages: PML body
messages: Postsynaptic density
messages: dendritic spine

9755:LOC102986932
gene id: 9755:LOC102986932
uniprot id: A0A2Y9S4T6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:SETD7
gene id: 9755:SETD7
uniprot id: A0A2Y9FCH4
uniprot id: A0A455BEV4
uniprot id: A0A455BFI5
uniprot id: A0A455BUI4
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

9755:NUF2
gene id: 9755:NUF2
uniprot id: A0A2Y9FW82
names: Similarity
messages: Belongs to the NUF2 family.

9755:LOC102986488
gene id: 9755:LOC102986488
uniprot id: A0A2Y9FBB2
names: Similarity
messages: Belongs to the serpin family.

9755:PCSK2
gene id: 9755:PCSK2
uniprot id: A0A2Y9EDF6
names: Similarity
messages: Belongs to the peptidase S8 family.

9755:ORC4
gene id: 9755:ORC4
uniprot id: A0A2Y9ES89
uniprot id: A0A2Y9ESJ1
uniprot id: A0A455ANK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC4 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication.
messages: Nucleus

9755:RUNDC3B
gene id: 9755:RUNDC3B
uniprot id: A0A2Y9T5N7
names: Similarity
names: Subunit
messages: Belongs to the RUNDC3 family.
messages: Interacts with RAP2A.

9755:FER
gene id: 9755:FER
uniprot id: A0A2Y9SS99
uniprot id: A0A2Y9STQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.
messages: Cell membrane
messages: Membrane
messages: cytoskeleton

9755:POU4F3
gene id: 9755:POU4F3
uniprot id: A0A2Y9F5W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

9755:LOC102983077
gene id: 9755:LOC102983077
uniprot id: A0A2Y9SPV7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9755:TCL1A
gene id: 9755:TCL1A
uniprot id: A0A2Y9F1E9
names: Similarity
messages: Belongs to the TCL1 family.

9755:CNDP2
gene id: 9755:CNDP2
uniprot id: A0A2Y9F8G7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

9755:LOC102989341
gene id: 9755:LOC102989341
uniprot id: A0A2Y9FG05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

9755:CLCN2
gene id: 9755:CLCN2
uniprot id: A0A2Y9FHZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-2/CLCN2 subfamily.
messages: Cell membrane
messages: Membrane

9755:VHL
gene id: 9755:VHL
uniprot id: A0A2Y9F2M3
names: Similarity
messages: Belongs to the VHL family.

9755:TSEN34
gene id: 9755:TSEN34
uniprot id: A0A2Y9TF36
uniprot id: A0A2Y9TIF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.
messages: Nucleus

9755:SOHLH1
gene id: 9755:SOHLH1
uniprot id: A0A2Y9SUJ8
names: Subcellular Location Annotation
messages: Nucleus

9755:PHF19
gene id: 9755:PHF19
uniprot id: A0A2Y9T188
uniprot id: A0A455BKJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus

9755:LOC112064328
gene id: 9755:LOC112064328
uniprot id: A0A455AGD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H3 family.
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus

9755:LOC102973995
gene id: 9755:LOC102973995
uniprot id: A0A2Y9ENZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX17 family.
messages: Mitochondrion intermembrane space

9755:PRMT5
gene id: 9755:PRMT5
uniprot id: A0A2Y9EFD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA).
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Nucleus

9755:EML4
gene id: 9755:EML4
uniprot id: A0A2Y9F035
uniprot id: A0A2Y9F0V3
uniprot id: A0A455BVV3
uniprot id: A0A455C931
names: Similarity
messages: Belongs to the WD repeat EMAP family.

9755:CHST3
gene id: 9755:CHST3
uniprot id: A0A2Y9EMH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

9755:CPSF2
gene id: 9755:CPSF2
uniprot id: A0A2Y9TFA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

9755:METAP1D
gene id: 9755:METAP1D
uniprot id: A0A2Y9SI67
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

9755:DOCK11
gene id: 9755:DOCK11
uniprot id: A0A2Y9SYX4
uniprot id: A0A2Y9SYX9
uniprot id: A0A2Y9T4Z8
names: Similarity
messages: Belongs to the DOCK family.

9755:TLR2
gene id: 9755:TLR2
uniprot id: A0A2Y9SW14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
messages: Membrane

9755:KEF67 p01
gene id: 9755:KEF67_p01
uniprot id: P41290
uniprot id: Q7HNZ6
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme b groups non-covalently.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
messages: Heme 1 (or BL or b562) is low-potential and absorbs at about 562 nm, and heme 2 (or BH or b566) is high-potential and absorbs at about 566 nm.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The cytochrome bc1 complex contains 11 subunits: 3 respiratory subunits (MT-CYB, CYC1 and UQCRFS1), 2 core proteins (UQCRC1 and UQCRC2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of UQCRFS1). This cytochrome bc1 complex then forms a dimer.
messages: The full-length protein contains only eight transmembrane helices, not nine as predicted by bioinformatics tools.

9755:INTS2
gene id: 9755:INTS2
uniprot id: A0A2Y9ET44
uniprot id: A0A2Y9ETB7
uniprot id: A0A2Y9SZC3
uniprot id: A0A2Y9T5U6
names: Similarity
messages: Belongs to the Integrator subunit 2 family.

9755:SULT1E1
gene id: 9755:SULT1E1
uniprot id: A0A2Y9EZE1
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9755:LOC102976077
gene id: 9755:LOC102976077
uniprot id: A0A2Y9SM16
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Involved in nucleotide metabolism via production of dUMP, the immediate precursor of thymidine nucleotides, and decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

9755:TGFBI
gene id: 9755:TGFBI
uniprot id: A0A2Y9F537
names: Subcellular Location Annotation
messages: extracellular matrix

9755:FBXO45
gene id: 9755:FBXO45
uniprot id: A0A2Y9SNB1
names: Similarity
messages: Belongs to the FBXO45/Fsn family.

9755:MTG1
gene id: 9755:MTG1
uniprot id: A0A2Y9SIS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Mitochondrion inner membrane
messages: Plays a role in the regulation of the mitochondrial ribosome assembly and of translational activity. Displays mitochondrial GTPase activity.

9755:DKC1
gene id: 9755:DKC1
uniprot id: A0A2Y9S1T3
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

9755:TSPO
gene id: 9755:TSPO
uniprot id: A0A455BRJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

9755:LOC102990067
gene id: 9755:LOC102990067
uniprot id: A0A2Y9SYL4
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.

9755:NSUN6
gene id: 9755:NSUN6
uniprot id: A0A2Y9EGM9
uniprot id: A0A2Y9EH89
uniprot id: A0A2Y9S8P0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

9755:XKR7
gene id: 9755:XKR7
uniprot id: A0A2Y9T7B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

9755:S100A10
gene id: 9755:S100A10
uniprot id: A0A2Y9FGV5
uniprot id: A0A455B9H5
names: Function
messages: Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine-specific kinase.

9755:LOC102988100
gene id: 9755:LOC102988100
uniprot id: A0A455BTL0
names: Similarity
messages: Belongs to the serpin family.

9755:AQP2
gene id: 9755:AQP2
uniprot id: A0A2Y9ERU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

9755:LOC102990412
gene id: 9755:LOC102990412
uniprot id: A0A2Y9T5M5
uniprot id: A0A2Y9TBJ6
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

9755:LOC102985988
gene id: 9755:LOC102985988
uniprot id: A0A2Y9SJB3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:PRIM1
gene id: 9755:PRIM1
uniprot id: A0A2Y9FRW8
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

9755:SULT4A1
gene id: 9755:SULT4A1
uniprot id: A0A2Y9T2Z8
uniprot id: A0A455BBZ5
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9755:TBX5
gene id: 9755:TBX5
uniprot id: A0A2Y9ELR5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9755:AHR
gene id: 9755:AHR
uniprot id: A0A2Y9EE85
names: Subcellular Location Annotation
messages: Cytoplasm

9755:RARS2
gene id: 9755:RARS2
uniprot id: A0A2Y9EJI8
uniprot id: A0A455C3F0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9755:MYG1
gene id: 9755:MYG1
uniprot id: A0A2Y9FKQ3
names: Similarity
messages: Belongs to the MYG1 family.

9755:COQ7
gene id: 9755:COQ7
uniprot id: A0A2Y9EKW2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone-independent manner.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ6. Interacts with COQ9.
messages: Mitochondrion inner membrane

9755:SNX18
gene id: 9755:SNX18
uniprot id: A0A2Y9F764
uniprot id: A0A455BIQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

9755:COL4A2
gene id: 9755:COL4A2
uniprot id: A0A2Y9SJS5
uniprot id: A0A2Y9SR44
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

9755:BRCA1
gene id: 9755:BRCA1
uniprot id: A0A455BY27
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Chromosome
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Regulates centrosomal microtubule nucleation. Required for appropriate cell cycle arrests after ionizing irradiation in both the S-phase and the G2 phase of the cell cycle. Required for FANCD2 targeting to sites of DNA damage. Inhibits lipid synthesis by binding to inactive phosphorylated ACACA and preventing its dephosphorylation. Contributes to homologous recombination repair (HRR) via its direct interaction with PALB2, fine-tunes recombinational repair partly through its modulatory role in the PALB2-dependent loading of BRCA2-RAD51 repair machinery at DNA breaks. Component of the BRCA1-RBBP8 complex which regulates CHEK1 activation and controls cell cycle G2/M checkpoints on DNA damage via BRCA1-mediated ubiquitination of RBBP8. Acts as a transcriptional activator.
messages: Heterodimer with BARD1. Part of the BRCA1-associated genome surveillance complex (BASC), which contains BRCA1, MSH2, MSH6, MLH1, ATM, BLM, PMS2 and the MRE11-RAD50-NBN protein (MRN) complex. This association could be a dynamic process changing throughout the cell cycle and within subnuclear domains. Component of the BRCA1-A complex, at least composed of BRCA1, BARD1, UIMC1/RAP80, ABRAXAS1, BRCC3/BRCC36, BABAM2 and BABAM1/NBA1. Interacts (via the BRCT domains) with ABRAXAS1 (phosphorylated form); this is important for recruitment to sites of DNA damage. Can form a heterotetramer with two molecules of ABRAXAS1 (phosphorylated form). Component of the BRCA1-RBBP8 complex. Interacts (via the BRCT domains) with RBBP8 ('Ser-327' phosphorylated form); the interaction ubiquitinates RBBP8, regulates CHEK1 activation, and involves RBBP8 in BRCA1-dependent G2/M checkpoint control on DNA damage. Associates with RNA polymerase II holoenzyme. Interacts with SMC1A, NELFB, DCLRE1C, CLSPN. CHEK1, CHEK2, BAP1, BRCC3, UBXN1 and PCLAF. Interacts (via BRCT domains) with BRIP1 (phosphorylated form). Interacts with FANCD2 (ubiquitinated form). Interacts with H2AX (phosphorylated on 'Ser-140'). Interacts (via the BRCT domains) with ACACA (phosphorylated form); the interaction prevents dephosphorylation of ACACA. Part of a BRCA complex containing BRCA1, BRCA2 and PALB2. Interacts directly with PALB2; the interaction is essential for its function in HRR. Interacts directly with BRCA2; the interaction occurs only in the presence of PALB2 which serves as the bridging protein. Interacts (via the BRCT domains) with LMO4; the interaction represses the transcriptional activity of BRCA1. Interacts (via the BRCT domains) with CCAR2 (via N-terminus); the interaction represses the transcriptional activator activity of BRCA1. Interacts with EXD2. Interacts (via C-terminus) with DHX9; this interaction is direct and links BRCA1 to the RNA polymerase II holoenzyme.
messages: Nucleus

9755:TM4SF19
gene id: 9755:TM4SF19
uniprot id: A0A2Y9SWF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

9755:TMEM145
gene id: 9755:TMEM145
uniprot id: A0A2Y9TC70
uniprot id: A0A2Y9TG30
uniprot id: A0A2Y9TI12
uniprot id: A0A455AB58
uniprot id: A0A455AB94
uniprot id: A0A455ADC3
uniprot id: A0A455AMU2
names: Subcellular Location Annotation
messages: Membrane

9755:KCNA6
gene id: 9755:KCNA6
uniprot id: A0A2Y9T3T1
uniprot id: A0A2Y9T5W1
names: Subcellular Location Annotation
messages: Membrane

9755:POLH
gene id: 9755:POLH
uniprot id: A0A2Y9ES20
uniprot id: A0A2Y9SGX9
names: Subcellular Location Annotation
messages: Nucleus

9755:LOC102973253
gene id: 9755:LOC102973253
uniprot id: A0A2Y9FJ92
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPCAM family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:ACTL6A
gene id: 9755:ACTL6A
uniprot id: A0A2Y9EP90
names: Similarity
messages: Belongs to the actin family.

9755:BRS3
gene id: 9755:BRS3
uniprot id: A0A2Y9EEB2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with C6orf89.
messages: Membrane

9755:UBE2D2
gene id: 9755:UBE2D2
uniprot id: A0A2Y9SHP1
uniprot id: A0A455BJR1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9755:MYF5
gene id: 9755:MYF5
uniprot id: A0A2Y9F301
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.
messages: Nucleus

9755:AKR1A1
gene id: 9755:AKR1A1
uniprot id: A0A2Y9EVD9
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the aldo/keto reductase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

9755:LOC102991696
gene id: 9755:LOC102991696
uniprot id: A0A2Y9SF37
uniprot id: A0A2Y9SKW2
uniprot id: A0A2Y9SMM8
names: Subcellular Location Annotation
messages: centrosome

9755:ATP6V0A2
gene id: 9755:ATP6V0A2
uniprot id: A0A2Y9FJX0
uniprot id: A0A2Y9SJH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

9755:IFNG
gene id: 9755:IFNG
uniprot id: A0A2Y9EPI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II (or gamma) interferon family.
messages: Homodimer. Interacts with IFNGR1 (via extracellular domain); this interaction promotes IFNGR1 dimerization.
messages: Secreted
messages: Type II interferon produced by immune cells such as T-cells and NK cells that plays crucial roles in antimicrobial, antiviral, and antitumor responses by activating effector immune cells and enhancing antigen presentation. Primarily signals through the JAK-STAT pathway after interaction with its receptor IFNGR1 to affect gene regulation. Upon IFNG binding, IFNGR1 intracellular domain opens out to allow association of downstream signaling components JAK2, JAK1 and STAT1, leading to STAT1 activation, nuclear translocation and transcription of IFNG-regulated genes. Many of the induced genes are transcription factors such as IRF1 that are able to further drive regulation of a next wave of transcription. Plays a role in class I antigen presentation pathway by inducing a replacement of catalytic proteasome subunits with immunoproteasome subunits. In turn, increases the quantity, quality, and repertoire of peptides for class I MHC loading. Increases the efficiency of peptide generation also by inducing the expression of activator PA28 that associates with the proteasome and alters its proteolytic cleavage preference. Up-regulates as well MHC II complexes on the cell surface by promoting expression of several key molecules such as cathepsins B/CTSB, H/CTSH, and L/CTSL. Participates in the regulation of hematopoietic stem cells during development and under homeostatic conditions by affecting their development, quiescence, and differentiation.

9755:GGNBP2
gene id: 9755:GGNBP2
uniprot id: A0A2Y9F443
uniprot id: A0A2Y9F482
uniprot id: A0A2Y9F5Y1
uniprot id: A0A2Y9F5Y5
uniprot id: A0A2Y9SXQ4
uniprot id: A0A455C3K6
names: Function
messages: May be involved in spermatogenesis.

9755:KCNK2
gene id: 9755:KCNK2
uniprot id: A0A2Y9TKJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

9755:LOC102990244
gene id: 9755:LOC102990244
uniprot id: A0A2Y9FK65
names: Subcellular Location Annotation
messages: Nucleus

9755:PANX3
gene id: 9755:PANX3
uniprot id: A0A2Y9F9T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

9755:LOC112065324
gene id: 9755:LOC112065324
uniprot id: A0A2Y9SRV9
uniprot id: A0A2Y9SVM5
names: Similarity
messages: Belongs to the TPRG1 family.

9755:RAB9B
gene id: 9755:RAB9B
uniprot id: A0A2Y9FHJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: phagosome membrane

9755:SPDYC
gene id: 9755:SPDYC
uniprot id: A0A2Y9F8Y9
names: Similarity
messages: Belongs to the Speedy/Ringo family.

9755:SH3PXD2A
gene id: 9755:SH3PXD2A
uniprot id: A0A455ALT1
uniprot id: A0A455ANK1
uniprot id: A0A455ANL0
uniprot id: A0A455ANW1
uniprot id: A0A455B0J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3PXD2 family.
messages: Cytoplasm

9755:PPP2R2A
gene id: 9755:PPP2R2A
uniprot id: A0A2Y9FRF2
uniprot id: A0A455BLZ2
uniprot id: A0A455BQ94
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

9755:SLC13A3
gene id: 9755:SLC13A3
uniprot id: A0A2Y9F7B5
uniprot id: A0A455CAL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

9755:FAM234B
gene id: 9755:FAM234B
uniprot id: A0A455BDM0
names: Similarity
messages: Belongs to the FAM234 family.

9755:TMEM70
gene id: 9755:TMEM70
uniprot id: A0A2Y9F792
names: Similarity
messages: Belongs to the TMEM70 family.

9755:GPRIN3
gene id: 9755:GPRIN3
uniprot id: A0A2Y9END1
names: Function
messages: May be involved in neurite outgrowth.

9755:PEX1
gene id: 9755:PEX1
uniprot id: A0A2Y9EJP5
uniprot id: A0A455BA15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: cytosol

9755:DDX53
gene id: 9755:DDX53
uniprot id: A0A2Y9S4A0
names: Similarity
messages: Belongs to the DEAD box helicase family.

9755:UBE2E2
gene id: 9755:UBE2E2
uniprot id: A0A2Y9S0E1
uniprot id: A0A455BBJ3
uniprot id: A0A455BBJ8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9755:LOC102979971
gene id: 9755:LOC102979971
uniprot id: A0A455B5W7
names: Similarity
messages: Belongs to the BEX family.

9755:ACAA1
gene id: 9755:ACAA1
uniprot id: A0A455AI42
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

9755:ATRN
gene id: 9755:ATRN
uniprot id: A0A2Y9S2S9
uniprot id: A0A2Y9SAT0
uniprot id: A0A455C051
uniprot id: A0A455C058
uniprot id: A0A455C4A7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:USP44
gene id: 9755:USP44
uniprot id: A0A2Y9FJP0
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

9755:GON4L
gene id: 9755:GON4L
uniprot id: A0A2Y9EWM5
names: Subcellular Location Annotation
messages: Nucleus

9755:CAPN2
gene id: 9755:CAPN2
uniprot id: A0A2Y9TCF9
uniprot id: A0A2Y9TEI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C2 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

9755:LOC102994740
gene id: 9755:LOC102994740
uniprot id: A0A2Y9RZZ3
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9755:PM20D2
gene id: 9755:PM20D2
uniprot id: A0A2Y9S8K4
names: Function
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Catalyzes the peptide bond hydrolysis in dipeptides having basic amino acids lysine, ornithine or arginine at C-terminus.

9755:KCNH8
gene id: 9755:KCNH8
uniprot id: A0A2Y9S459
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

9755:RPP14
gene id: 9755:RPP14
uniprot id: A0A2Y9F9X6
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.

9755:SLC6A5
gene id: 9755:SLC6A5
uniprot id: A0A2Y9FHD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

9755:LOC114487161
gene id: 9755:LOC114487161
uniprot id: A0A455BRW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 16 family.
messages: Nucleus

9755:SLC33A1
gene id: 9755:SLC33A1
uniprot id: A0A2Y9EQP0
uniprot id: A0A455BBW5
uniprot id: A0A455BQQ5
names: Subcellular Location Annotation
messages: Membrane

9755:CFAP97
gene id: 9755:CFAP97
uniprot id: A0A2Y9EZ95
names: Similarity
messages: Belongs to the CFAP97 family.

9755:SLC13A4
gene id: 9755:SLC13A4
uniprot id: A0A2Y9TBE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

9755:SEPHS2
gene id: 9755:SEPHS2
uniprot id: A0A2Y9FUS3
names: Function
messages: Synthesizes selenophosphate from selenide and ATP.

9755:OSBPL6
gene id: 9755:OSBPL6
uniprot id: A0A2Y9SP62
names: Similarity
messages: Belongs to the OSBP family.

9755:LOC114484129
gene id: 9755:LOC114484129
uniprot id: A0A455AQH7
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9755:CHUK
gene id: 9755:CHUK
uniprot id: A0A2Y9F901
uniprot id: A0A2Y9SI37
uniprot id: A0A455AM15
uniprot id: A0A455ANU5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9755:UROC1
gene id: 9755:UROC1
uniprot id: A0A2Y9SB93
names: Similarity
messages: Belongs to the urocanase family.

9755:IRF2BPL
gene id: 9755:IRF2BPL
uniprot id: A0A2Y9ERS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF2BP family.
messages: Nucleus

9755:SMS
gene id: 9755:SMS
uniprot id: A0A2Y9S4F0
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

9755:LOC112063838
gene id: 9755:LOC112063838
uniprot id: A0A2Y9FUK9
names: Similarity
messages: Belongs to the ANKRD34 family.

9755:STK40
gene id: 9755:STK40
uniprot id: A0A2Y9F4V7
uniprot id: A0A455BDK0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be a negative regulator of NF-kappa-B and p53-mediated gene transcription.
messages: Nucleus

9755:CNRIP1
gene id: 9755:CNRIP1
uniprot id: A0A2Y9FNV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CNRIP family.
messages: Interacts with the cannabinoid receptor CNR1 (via C-terminus). Does not interact with cannabinoid receptor CNR2.
messages: Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels.

9755:RAD1
gene id: 9755:RAD1
uniprot id: A0A2Y9FGY8
uniprot id: A0A2Y9FH13
uniprot id: A0A2Y9FH54
uniprot id: A0A2Y9FHD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad1 family.
messages: Nucleus

9755:AMIGO2
gene id: 9755:AMIGO2
uniprot id: A0A2Y9EYA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. AMIGO family.
messages: Membrane

9755:CCNA1
gene id: 9755:CCNA1
uniprot id: A0A2Y9FR21
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

9755:LOC102990956
gene id: 9755:LOC102990956
uniprot id: A0A455AP00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: cytoskeleton

9755:VAMP2
gene id: 9755:VAMP2
uniprot id: A0A2Y9T2K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

9755:ZSCAN22
gene id: 9755:ZSCAN22
uniprot id: A0A2Y9S2B1
names: Subcellular Location Annotation
messages: Nucleus

9755:LOC112062578
gene id: 9755:LOC112062578
uniprot id: A0A2Y9S9U9
names: Similarity
messages: Belongs to the histone H2B family.

9755:IL4R
gene id: 9755:IL4R
uniprot id: A0A2Y9SSQ9
uniprot id: A0A455C1H0
names: Function
names: Similarity
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.

9755:ADAMTS18
gene id: 9755:ADAMTS18
uniprot id: A0A2Y9SU07
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9755:FANCM
gene id: 9755:FANCM
uniprot id: A0A2Y9F0N5
uniprot id: A0A2Y9F1X0
uniprot id: A0A455BRJ8
uniprot id: A0A455BUX0
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.

9755:LOC102994695
gene id: 9755:LOC102994695
uniprot id: A0A2Y9TGP1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:S100A11
gene id: 9755:S100A11
uniprot id: A0A2Y9FGZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the S-100 family.
messages: Facilitates the differentiation and the cornification of keratinocytes.
messages: Homodimer; disulfide-linked.

9755:LOC102977187
gene id: 9755:LOC102977187
uniprot id: A0A2Y9F8B2
uniprot id: A0A2Y9SDM2
names: Function
names: Similarity
messages: Belongs to the TYW1 family.
messages: Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis.

9755:MFSD14B
gene id: 9755:MFSD14B
uniprot id: A0A2Y9FGJ6
uniprot id: A0A2Y9S2X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

9755:KCNK12
gene id: 9755:KCNK12
uniprot id: A0A2Y9S7E7
uniprot id: A0A455BVK0
uniprot id: A0A455BZ09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

9755:PEX3
gene id: 9755:PEX3
uniprot id: A0A2Y9F3A6
uniprot id: A0A2Y9F4D7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with PEX19.
messages: Involved in peroxisome biosynthesis and integrity. Assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in the peroxisomes.
messages: Peroxisome membrane

9755:LOC102983962
gene id: 9755:LOC102983962
uniprot id: A0A2Y9FFV8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9755:SSX2IP
gene id: 9755:SSX2IP
uniprot id: A0A2Y9S9V6
uniprot id: A0A2Y9SAL0
uniprot id: A0A2Y9SAL5
uniprot id: A0A2Y9SDL8
uniprot id: A0A2Y9SGM2
uniprot id: A0A2Y9SI86
uniprot id: A0A455B896
uniprot id: A0A455BM88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIP family.
messages: adherens junction
messages: centriolar satellite

9755:LOC102992701
gene id: 9755:LOC102992701
uniprot id: A0A2Y9THZ7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:NRDE2
gene id: 9755:NRDE2
uniprot id: A0A2Y9EJ76
names: Similarity
messages: Belongs to the NRDE2 family.

9755:LOC102989132
gene id: 9755:LOC102989132
uniprot id: A0A2Y9SUX0
uniprot id: A0A455BDU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argonaute family. Ago subfamily.
messages: Interacts with EIF4B, IMP8, PRMT5, TNRC6A and TNRC6B. Interacts with ZFP36.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.

9755:LOC102994115
gene id: 9755:LOC102994115
uniprot id: A0A2Y9TBF0
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

9755:OPALIN
gene id: 9755:OPALIN
uniprot id: A0A2Y9SEW6
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Central nervous system-specific myelin protein that increase myelin genes expression during oligodendrocyte differentiation. Promotes oligodendrocyte terminal differentiation.
messages: Membrane

9755:KCNC4
gene id: 9755:KCNC4
uniprot id: A0A2Y9EQ09
uniprot id: A0A2Y9SAR4
uniprot id: A0A2Y9SHG5
uniprot id: A0A2Y9SJ09
uniprot id: A0A455B7A6
uniprot id: A0A455BLS1
names: Subcellular Location Annotation
messages: Membrane

9755:LOC102974196
gene id: 9755:LOC102974196
uniprot id: A0A2Y9EV03
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

9755:DDX3X
gene id: 9755:DDX3X
uniprot id: A0A2Y9FEA2
uniprot id: A0A2Y9FEH5
names: Similarity
messages: Belongs to the DEAD box helicase family.

9755:CLP1
gene id: 9755:CLP1
uniprot id: A0A2Y9FBJ4
uniprot id: A0A455C7H8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Clp1 family. Clp1 subfamily.
messages: Component of the tRNA splicing endonuclease complex, composed of CLP1, TSEN2, TSEN15, TSEN34 and TSEN54. Component of pre-mRNA cleavage complex II (CF-II). Also associates with numerous components of the pre-mRNA cleavage complex I (CF-I/CFIm), including NUDT21, CPSF2, CPSF3, CPSF6 and CPSF7. Interacts with CSTF2 and SYMPK.
messages: Nucleus
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; this phosphorylation event is a prerequisite for the subsequent ligation of the two exon halves and the production of a mature tRNA. Component of the pre-mRNA cleavage complex II (CF-II), which seems to be required for mRNA 3'-end formation. Also phosphorylates the 5'-terminus of exogenously introduced short interfering RNAs (siRNAs), which is a necessary prerequisite for their incorporation into the RNA-induced silencing complex (RISC). However, endogenous siRNAs and microRNAs (miRNAs) that are produced by the cleavage of dsRNA precursors by DICER1 already contain a 5'-phosphate group, so this protein may be dispensible for normal RNA-mediated gene silencing.

9755:LOC112062779
gene id: 9755:LOC112062779
uniprot id: A0A2Y9S864
names: Similarity
messages: Belongs to the histone H2B family.

9755:SERINC1
gene id: 9755:SERINC1
uniprot id: A0A2Y9F693
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

9755:BMP7
gene id: 9755:BMP7
uniprot id: A0A2Y9T1E2
uniprot id: A0A2Y9T7U1
names: Similarity
messages: Belongs to the TGF-beta family.

9755:LOC102995981
gene id: 9755:LOC102995981
uniprot id: A0A2Y9RZH4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:CPSF7
gene id: 9755:CPSF7
uniprot id: A0A2Y9ENX7
uniprot id: A0A2Y9EPE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CPSF6/7 family.
messages: Nucleus

9755:LOC102984303
gene id: 9755:LOC102984303
uniprot id: A0A2Y9FWD2
names: Similarity
messages: Belongs to the thioredoxin family.

9755:MARVELD2
gene id: 9755:MARVELD2
uniprot id: A0A2Y9FT17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

9755:TAF8
gene id: 9755:TAF8
uniprot id: A0A2Y9FDH4
uniprot id: A0A2Y9FFF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF8 family.
messages: Nucleus

9755:UBE2G2
gene id: 9755:UBE2G2
uniprot id: A0A2Y9SBP9
uniprot id: A0A2Y9SCG6
uniprot id: A0A2Y9SK16
uniprot id: A0A455BKY0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9755:LIN7C
gene id: 9755:LIN7C
uniprot id: A0A2Y9F979
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the lin-7 family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.
messages: Postsynaptic density membrane
messages: tight junction

9755:GTPBP4
gene id: 9755:GTPBP4
uniprot id: A0A2Y9EIN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

9755:RDH5
gene id: 9755:RDH5
uniprot id: A0A2Y9FL46
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9755:PEX7
gene id: 9755:PEX7
uniprot id: A0A2Y9FU40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat peroxin-7 family.
messages: Peroxisome matrix
messages: cytosol

9755:POU3F3
gene id: 9755:POU3F3
uniprot id: A0A2Y9S983
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

9755:NRM
gene id: 9755:NRM
uniprot id: A0A2Y9EPP9
uniprot id: A0A2Y9EQG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nurim family.
messages: Membrane
messages: Nucleus inner membrane

9755:LOC102978994
gene id: 9755:LOC102978994
uniprot id: A0A2Y9TAN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

9755:PTPRN
gene id: 9755:PTPRN
uniprot id: A0A2Y9FGJ1
uniprot id: A0A2Y9FGR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily.
messages: Membrane
messages: secretory vesicle membrane

9755:KAT6B
gene id: 9755:KAT6B
uniprot id: A0A2Y9TE41
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

9755:ATRNL1
gene id: 9755:ATRNL1
uniprot id: A0A2Y9SG69
uniprot id: A0A2Y9SNU8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:WHAMM
gene id: 9755:WHAMM
uniprot id: A0A2Y9SBK2
names: Subcellular Location Annotation
messages: Membrane

9755:NDUFS5
gene id: 9755:NDUFS5
uniprot id: A0A2Y9F0T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS5 subunit family.
messages: Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.
messages: Membrane
messages: Mitochondrion inner membrane

9755:ERF
gene id: 9755:ERF
uniprot id: A0A2Y9TJ41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9755:YIPF4
gene id: 9755:YIPF4
uniprot id: A0A2Y9EHL2
uniprot id: A0A455BY70
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:LOC102983336
gene id: 9755:LOC102983336
uniprot id: A0A455CBU8
names: Similarity
messages: Belongs to the FAM168 family.

9755:TRIM56
gene id: 9755:TRIM56
uniprot id: A0A2Y9FPC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIM/RBCC family.
messages: Cytoplasm

9755:INTS14
gene id: 9755:INTS14
uniprot id: A0A2Y9EM51
uniprot id: A0A2Y9ENI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INTS14 family.
messages: Nucleus
messages: Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.

9755:C18H6orf89
gene id: 9755:C18H6orf89
uniprot id: A0A2Y9SG30
uniprot id: A0A2Y9SPJ1
uniprot id: A0A455ARX4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

9755:LOC102987376
gene id: 9755:LOC102987376
uniprot id: A0A2Y9F5G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9755:LOC102991067
gene id: 9755:LOC102991067
uniprot id: A0A2Y9T9U4
uniprot id: A0A455B658
uniprot id: A0A455B7X7
uniprot id: A0A455BJJ3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:FOXE1
gene id: 9755:FOXE1
uniprot id: A0A2Y9T064
names: Subcellular Location Annotation
messages: Nucleus

9755:HYCC2
gene id: 9755:HYCC2
uniprot id: A0A2Y9ESI0
uniprot id: A0A2Y9ESQ7
uniprot id: A0A2Y9ET43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Hyccin family.
messages: Cell membrane
messages: Membrane
messages: cytosol

9755:TMPRSS11E
gene id: 9755:TMPRSS11E
uniprot id: A0A2Y9FIL8
uniprot id: A0A2Y9THL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Membrane

9755:PAM16
gene id: 9755:PAM16
uniprot id: A0A455C009
names: Similarity
messages: Belongs to the TIM16/PAM16 family.

9755:CCN3
gene id: 9755:CCN3
uniprot id: A0A2Y9FNU8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9755:GPHN
gene id: 9755:GPHN
uniprot id: A0A2Y9TJN6
uniprot id: A0A2Y9TKY0
uniprot id: A0A455BS64
uniprot id: A0A455BS72
uniprot id: A0A455BSV6
uniprot id: A0A455BVJ9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
messages: In the C-terminal section; belongs to the MoeA family.
messages: In the N-terminal section; belongs to the MoaB/Mog family.

9755:ADPRHL1
gene id: 9755:ADPRHL1
uniprot id: A0A2Y9SBQ3
uniprot id: A0A455BZJ3
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

9755:MECOM
gene id: 9755:MECOM
uniprot id: A0A2Y9EFH5
uniprot id: A0A2Y9EFI0
uniprot id: A0A2Y9EG72
uniprot id: A0A2Y9EH41
uniprot id: A0A2Y9EHE0
uniprot id: A0A2Y9SP23
uniprot id: A0A2Y9SRJ2
names: Subcellular Location Annotation
messages: Nucleus

9755:GPR21
gene id: 9755:GPR21
uniprot id: A0A2Y9FR35
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9755:EIF1B
gene id: 9755:EIF1B
uniprot id: A0A2Y9F798
names: Similarity
messages: Belongs to the SUI1 family.

9755:ZKSCAN2
gene id: 9755:ZKSCAN2
uniprot id: A0A2Y9EPI3
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

9755:DZIP3
gene id: 9755:DZIP3
uniprot id: A0A2Y9SJI4
uniprot id: A0A455BKE3
uniprot id: A0A455BNN1
names: Subcellular Location Annotation
messages: Cytoplasm

9755:ATP5ME
gene id: 9755:ATP5ME
uniprot id: A0A2Y9SF40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase e subunit family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

9755:NPY
gene id: 9755:NPY
uniprot id: A0A2Y9EXP0
uniprot id: A0A455B9Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

9755:MED15
gene id: 9755:MED15
uniprot id: A0A455AV71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 15 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

9755:LOC112066571
gene id: 9755:LOC112066571
uniprot id: A0A2Y9TAK0
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

9755:SUV39H2
gene id: 9755:SUV39H2
uniprot id: A0A2Y9S425
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
messages: Nucleus
messages: centromere

9755:LOC102977765
gene id: 9755:LOC102977765
uniprot id: A0A2Y9SIR8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:NAPG
gene id: 9755:NAPG
uniprot id: A0A2Y9FN05
uniprot id: A0A455AHA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

9755:GATA3
gene id: 9755:GATA3
uniprot id: A0A2Y9EJS0
uniprot id: A0A2Y9ELL5
names: Subcellular Location Annotation
messages: Nucleus

9755:EYA1
gene id: 9755:EYA1
uniprot id: A0A2Y9SW50
uniprot id: A0A455C4V9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

9755:TNFRSF11B
gene id: 9755:TNFRSF11B
uniprot id: A0A2Y9F9M4
names: Caution
names: Function
names: Subunit
messages: Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:GPRIN1
gene id: 9755:GPRIN1
uniprot id: A0A2Y9S077
names: Function
messages: May be involved in neurite outgrowth.

9755:NAP1L4
gene id: 9755:NAP1L4
uniprot id: A0A2Y9TD81
uniprot id: A0A455AG69
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9755:LOC102973517
gene id: 9755:LOC102973517
uniprot id: A0A2Y9TKU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

9755:TRIM45
gene id: 9755:TRIM45
uniprot id: A0A2Y9FC57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIM/RBCC family.
messages: Cytoplasm

9755:POMC
gene id: 9755:POMC
uniprot id: A0A2Y9SEL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Anorexigenic peptide. Increases the pigmentation of skin by increasing melanin production in melanocytes.
messages: Belongs to the POMC family.
messages: Endogenous opiate.
messages: Endogenous orexigenic opiate.
messages: Secreted
messages: Stimulates the adrenal glands to release cortisol.

9755:LOC102973644
gene id: 9755:LOC102973644
uniprot id: A0A455B6Z6
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

9755:PPP1R1C
gene id: 9755:PPP1R1C
uniprot id: A0A2Y9F3Z0
uniprot id: A0A2Y9F4X1
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 1 family.

9755:RPL37A
gene id: 9755:RPL37A
uniprot id: A0A2Y9SVG7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

9755:TUBD1
gene id: 9755:TUBD1
uniprot id: A0A2Y9FAA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: Nucleus
messages: centriole
messages: cilium

9755:RET
gene id: 9755:RET
uniprot id: A0A455AMB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane
messages: Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.

9755:SLC6A6
gene id: 9755:SLC6A6
uniprot id: A0A2Y9F7G1
uniprot id: A0A455AIS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A6 subfamily.
messages: Cell membrane
messages: Membrane

9755:TEFM
gene id: 9755:TEFM
uniprot id: A0A2Y9EPI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TEFM family.
messages: Transcription elongation factor which increases mitochondrial RNA polymerase processivity. Regulates transcription of the mitochondrial genome, including genes important for the oxidative phosphorylation machinery.
messages: mitochondrion nucleoid

9755:LOC102980393
gene id: 9755:LOC102980393
uniprot id: A0A2Y9F5C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: extracellular exosome

9755:LOC112064315
gene id: 9755:LOC112064315
uniprot id: A0A2Y9SMA6
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

9755:LOC102979194
gene id: 9755:LOC102979194
uniprot id: A0A455BWQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

9755:DRGX
gene id: 9755:DRGX
uniprot id: A0A2Y9FWZ2
names: Subcellular Location Annotation
messages: Nucleus

9755:PPIH
gene id: 9755:PPIH
uniprot id: A0A2Y9EWY5
uniprot id: A0A2Y9EXU9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

9755:BCOR
gene id: 9755:BCOR
uniprot id: A0A2Y9S7Q6
uniprot id: A0A455ANA5
uniprot id: A0A455APZ1
uniprot id: A0A455AQE3
names: Similarity
messages: Belongs to the BCOR family.

9755:SI
gene id: 9755:SI
uniprot id: A0A2Y9EU27
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:RND3
gene id: 9755:RND3
uniprot id: A0A2Y9FCZ6
names: Function
messages: Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.

9755:LOC102979294
gene id: 9755:LOC102979294
uniprot id: A0A2Y9FNE1
uniprot id: A0A455AAZ4
uniprot id: A0A455AAZ7
uniprot id: A0A455AB30
uniprot id: A0A455AC36
uniprot id: A0A455AC40
uniprot id: A0A455AD42
uniprot id: A0A455AMH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:DNASE1
gene id: 9755:DNASE1
uniprot id: A0A2Y9F0H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNase I family.
messages: Nucleus envelope
messages: Zymogen granule

9755:DSC3
gene id: 9755:DSC3
uniprot id: A0A2Y9FCM9
uniprot id: A0A2Y9FEH9
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

9755:PARP11
gene id: 9755:PARP11
uniprot id: A0A2Y9F8A3
uniprot id: A0A455BCL5
uniprot id: A0A455BDA7
uniprot id: A0A455BS73
names: Similarity
messages: Belongs to the ARTD/PARP family.

9755:RAB33A
gene id: 9755:RAB33A
uniprot id: A0A2Y9EJY9
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

9755:NR2C1
gene id: 9755:NR2C1
uniprot id: A0A2Y9SWX4
uniprot id: A0A2Y9T2V0
uniprot id: A0A455BBW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9755:ZC3H15
gene id: 9755:ZC3H15
uniprot id: A0A2Y9S1P5
names: Similarity
messages: Belongs to the ZC3H15/TMA46 family.

9755:UTP3
gene id: 9755:UTP3
uniprot id: A0A2Y9FB68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAS10 family.
messages: nucleolus

9755:TBXAS1
gene id: 9755:TBXAS1
uniprot id: A0A455B973
uniprot id: A0A455BA01
names: Similarity
messages: Belongs to the cytochrome P450 family.

9755:AGMAT
gene id: 9755:AGMAT
uniprot id: A0A2Y9SS10
uniprot id: A0A455B496
names: Similarity
messages: Belongs to the arginase family.
messages: Belongs to the arginase family. Agmatinase subfamily.

9755:PALS1
gene id: 9755:PALS1
uniprot id: A0A2Y9F5D9
uniprot id: A0A2Y9F5J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: Endomembrane system
messages: adherens junction
messages: tight junction

9755:TMEM63A
gene id: 9755:TMEM63A
uniprot id: A0A2Y9FRF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

9755:ATR
gene id: 9755:ATR
uniprot id: A0A2Y9FNJ8
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.

9755:DNAAF6
gene id: 9755:DNAAF6
uniprot id: A0A2Y9SZ37
names: Similarity
messages: Belongs to the PIH1 family.

9755:TMEM33
gene id: 9755:TMEM33
uniprot id: A0A2Y9FJZ5
uniprot id: A0A455BFR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

9755:FNBP1L
gene id: 9755:FNBP1L
uniprot id: A0A2Y9SE48
uniprot id: A0A455B7J5
uniprot id: A0A455B8E7
uniprot id: A0A455BM11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNBP1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Membrane
messages: Vesicle
messages: cell cortex
messages: cytoskeleton

9755:DXO
gene id: 9755:DXO
uniprot id: A0A2Y9EVZ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DXO/Dom3Z family.
messages: Binds 2 magnesium ions.
messages: Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
messages: Nucleus

9755:F12
gene id: 9755:F12
uniprot id: A0A2Y9S0D9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9755:SLC52A2
gene id: 9755:SLC52A2
uniprot id: A0A2Y9ELD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

9755:NUDT19
gene id: 9755:NUDT19
uniprot id: A0A2Y9EGU8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

9755:PPAT
gene id: 9755:PPAT
uniprot id: A0A2Y9F640
uniprot id: A0A2Y9F689
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

9755:LOC112062006
gene id: 9755:LOC112062006
uniprot id: A0A2Y9RXH8
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9755:FOXC2
gene id: 9755:FOXC2
uniprot id: A0A2Y9SW41
names: Subcellular Location Annotation
messages: Nucleus

9755:PTGES3
gene id: 9755:PTGES3
uniprot id: A0A2Y9FTT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the p23/wos2 family.
messages: Cytoplasm
messages: Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation.
messages: Forms a complex with HSP70, HSP90 and other chaperones.

9755:RICTOR
gene id: 9755:RICTOR
uniprot id: A0A2Y9ESK4
uniprot id: A0A2Y9EST2
uniprot id: A0A2Y9ET67
uniprot id: A0A2Y9ET72
uniprot id: A0A2Y9ETZ1
uniprot id: A0A2Y9EUI2
uniprot id: A0A455BIU7
names: Similarity
messages: Belongs to the RICTOR family.

9755:PAPPA2
gene id: 9755:PAPPA2
uniprot id: A0A2Y9TGZ3
names: Caution
names: Similarity
messages: Belongs to the peptidase M43B family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:EIF2S1
gene id: 9755:EIF2S1
uniprot id: A0A2Y9F653
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2-alpha family.
messages: Stress granule

9755:LOC112063603
gene id: 9755:LOC112063603
uniprot id: A0A2Y9S6Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

9755:ATP4B
gene id: 9755:ATP4B
uniprot id: A0A2Y9F7W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

9755:SH3BP5
gene id: 9755:SH3BP5
uniprot id: A0A2Y9S4V3
uniprot id: A0A455BAP6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

9755:MMP27
gene id: 9755:MMP27
uniprot id: A0A2Y9F5L4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

9755:CLCF1
gene id: 9755:CLCF1
uniprot id: A0A2Y9TJC5
uniprot id: A0A455C9M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

9755:GK5
gene id: 9755:GK5
uniprot id: A0A2Y9T9Q0
names: Similarity
messages: Belongs to the FGGY kinase family.

9755:UBR1
gene id: 9755:UBR1
uniprot id: A0A2Y9FCP9
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

9755:TSPYL2
gene id: 9755:TSPYL2
uniprot id: A0A2Y9F6I7
uniprot id: A0A2Y9F774
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9755:ST3GAL4
gene id: 9755:ST3GAL4
uniprot id: A0A2Y9FLA7
uniprot id: A0A455C6J8
uniprot id: A0A455C6T0
uniprot id: A0A455CBU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9755:LOC102976445
gene id: 9755:LOC102976445
uniprot id: A0A2Y9S7G5
uniprot id: A0A455C4G4
names: Similarity
messages: Belongs to the FAM83 family.

9755:CENPL
gene id: 9755:CENPL
uniprot id: A0A2Y9F6J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-L/IML3 family.
messages: Nucleus

9755:CLN5
gene id: 9755:CLN5
uniprot id: A0A2Y9SKG1
uniprot id: A0A455C9Y9
names: Similarity
messages: Belongs to the CLN5 family.

9755:PER2
gene id: 9755:PER2
uniprot id: A0A2Y9SQC3
uniprot id: A0A455AQM9
uniprot id: A0A455AST3
uniprot id: A0A455ASU3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9755:PRDM4
gene id: 9755:PRDM4
uniprot id: A0A2Y9T587
names: Function
names: Subcellular Location Annotation
messages: May function as a transcription factor involved in cell differentiation.
messages: Nucleus

9755:DNMT3L
gene id: 9755:DNMT3L
uniprot id: A0A2Y9FSY6
names: Subcellular Location Annotation
messages: Nucleus

9755:GCSH
gene id: 9755:GCSH
uniprot id: A0A2Y9FK22
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

9755:SFRP5
gene id: 9755:SFRP5
uniprot id: A0A2Y9FNW8
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:SNRNP27
gene id: 9755:SNRNP27
uniprot id: A0A2Y9F254
uniprot id: A0A455BV61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNUT3 family.
messages: May play a role in mRNA splicing.
messages: Nucleus
messages: Part of a tri-snRNP complex.

9755:SNX33
gene id: 9755:SNX33
uniprot id: A0A2Y9FAV1
uniprot id: A0A2Y9FAV6
uniprot id: A0A2Y9FB80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

9755:TBX22
gene id: 9755:TBX22
uniprot id: A0A2Y9EXN5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9755:CALCR
gene id: 9755:CALCR
uniprot id: A0A2Y9T9P0
uniprot id: A0A2Y9TFP0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Interacts with GPRASP2.
messages: Membrane

9755:ANK1
gene id: 9755:ANK1
uniprot id: A0A455APR9
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

9755:TBP
gene id: 9755:TBP
uniprot id: A0A2Y9SRW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

9755:TONSL
gene id: 9755:TONSL
uniprot id: A0A2Y9EMY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tonsoku family.
messages: Chromosome

9755:KCNH1
gene id: 9755:KCNH1
uniprot id: A0A2Y9TFA2
names: Subcellular Location Annotation
messages: Membrane

9755:SEPTIN6
gene id: 9755:SEPTIN6
uniprot id: A0A2Y9T4U0
uniprot id: A0A2Y9T4U6
uniprot id: A0A2Y9T6Q6
uniprot id: A0A2Y9T6R1
uniprot id: A0A455AMU3
uniprot id: A0A455AN19
uniprot id: A0A455B1L6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

9755:CDC42BPA
gene id: 9755:CDC42BPA
uniprot id: A0A2Y9T7S7
uniprot id: A0A2Y9T7T5
uniprot id: A0A2Y9T9H3
uniprot id: A0A2Y9T9H8
uniprot id: A0A455B5I8
uniprot id: A0A455B5W2
uniprot id: A0A455B5W8
uniprot id: A0A455B5X4
uniprot id: A0A455B6F3
uniprot id: A0A455B6F7
uniprot id: A0A455B894
uniprot id: A0A455BJW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
messages: Cytoplasm
messages: lamellipodium

9755:CDCA2
gene id: 9755:CDCA2
uniprot id: A0A2Y9FD81
uniprot id: A0A2Y9FDF1
uniprot id: A0A2Y9FDM1
uniprot id: A0A2Y9FFB6
names: Subcellular Location Annotation
messages: Nucleus

9755:LOC102987154
gene id: 9755:LOC102987154
uniprot id: A0A2Y9SC58
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:ARHGDIG
gene id: 9755:ARHGDIG
uniprot id: A0A2Y9SM11
names: Similarity
messages: Belongs to the Rho GDI family.

9755:TMEM9
gene id: 9755:TMEM9
uniprot id: A0A455B540
uniprot id: A0A455BJD9
names: Similarity
messages: Belongs to the TMEM9 family.

9755:BPNT2
gene id: 9755:BPNT2
uniprot id: A0A2Y9F1D2
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

9755:OVOL1
gene id: 9755:OVOL1
uniprot id: A0A2Y9TDS4
names: Subcellular Location Annotation
messages: Nucleus

9755:TBCE
gene id: 9755:TBCE
uniprot id: A0A2Y9RYV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCE family.
messages: Cytoplasm

9755:RDX
gene id: 9755:RDX
uniprot id: A0A2Y9FA11
uniprot id: A0A2Y9TBH9
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton
messages: microvillus

9755:LOC112064227
gene id: 9755:LOC112064227
uniprot id: A0A2Y9SNE9
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

9755:SPSB3
gene id: 9755:SPSB3
uniprot id: A0A2Y9EDI5
uniprot id: A0A2Y9EE51
uniprot id: A0A2Y9SUK8
uniprot id: A0A455C1I6
names: Function
names: Similarity
messages: Belongs to the SPSB family.
messages: May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

9755:EVC2
gene id: 9755:EVC2
uniprot id: A0A2Y9SD80
names: Subcellular Location Annotation
messages: Membrane
messages: cilium basal body
messages: cilium membrane

9755:PTN
gene id: 9755:PTN
uniprot id: A0A2Y9EYN1
uniprot id: A0A2Y9EYT2
uniprot id: A0A2Y9T3A6
uniprot id: A0A2Y9T3D2
uniprot id: A0A2Y9T5E0
names: Similarity
messages: Belongs to the pleiotrophin family.

9755:KCNK6
gene id: 9755:KCNK6
uniprot id: A0A2Y9TDI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

9755:RAD18
gene id: 9755:RAD18
uniprot id: A0A2Y9SMN0
uniprot id: A0A2Y9SNJ9
uniprot id: A0A2Y9SR33
uniprot id: A0A2Y9SR38
uniprot id: A0A2Y9STS1
uniprot id: A0A2Y9SVU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD18 family.
messages: Nucleus

9755:NDST2
gene id: 9755:NDST2
uniprot id: A0A2Y9F4F7
uniprot id: A0A2Y9F596
uniprot id: A0A455ALH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

9755:LOC112065309
gene id: 9755:LOC112065309
uniprot id: A0A2Y9SZI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:NPY2R
gene id: 9755:NPY2R
uniprot id: A0A2Y9FB77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9755:SLC22A8
gene id: 9755:SLC22A8
uniprot id: A0A2Y9EWW0
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

9755:CTNNBIP1
gene id: 9755:CTNNBIP1
uniprot id: A0A2Y9EWY2
uniprot id: A0A2Y9EXE4
names: Similarity
messages: Belongs to the CTNNBIP1 family.

9755:SLC15A1
gene id: 9755:SLC15A1
uniprot id: A0A2Y9EGT6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Interacts (via extracellular domain region) with trypsin.
messages: Membrane

9755:GCG
gene id: 9755:GCG
uniprot id: A0A2Y9EMW7
uniprot id: A0A2Y9EP01
names: Similarity
messages: Belongs to the glucagon family.

9755:GLB1
gene id: 9755:GLB1
uniprot id: A0A2Y9FM70
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

9755:ITPKA
gene id: 9755:ITPKA
uniprot id: A0A2Y9EYY2
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

9755:CAMK1D
gene id: 9755:CAMK1D
uniprot id: A0A2Y9T4S3
uniprot id: A0A2Y9TBC4
names: Similarity
messages: Belongs to the protein kinase superfamily.

9755:NPY5R
gene id: 9755:NPY5R
uniprot id: A0A2Y9F6Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders.

9755:PRIMPOL
gene id: 9755:PRIMPOL
uniprot id: A0A2Y9EHH3
uniprot id: A0A2Y9EIW9
uniprot id: A0A455AMK1
uniprot id: A0A455APD8
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

9755:PCLO
gene id: 9755:PCLO
uniprot id: A0A2Y9T7N1
names: Subcellular Location Annotation
messages: Presynaptic active zone

9755:SNX6
gene id: 9755:SNX6
uniprot id: A0A2Y9S6K3
names: Function
names: Similarity
messages: Belongs to the sorting nexin family.
messages: Involved in several stages of intracellular trafficking.

9755:WNT8A
gene id: 9755:WNT8A
uniprot id: A0A2Y9FGS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9755:GPM6A
gene id: 9755:GPM6A
uniprot id: A0A2Y9FNT4
uniprot id: A0A455ALR4
uniprot id: A0A455AN84
uniprot id: A0A455B074
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

9755:DDX42
gene id: 9755:DDX42
uniprot id: A0A2Y9TAC5
names: Similarity
messages: Belongs to the DEAD box helicase family.

9755:YPEL4
gene id: 9755:YPEL4
uniprot id: A0A2Y9FBK7
uniprot id: A0A2Y9TJ76
names: Similarity
messages: Belongs to the yippee family.

9755:CXCL11
gene id: 9755:CXCL11
uniprot id: A0A2Y9FJ13
uniprot id: A0A2Y9S0Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

9755:CEP63
gene id: 9755:CEP63
uniprot id: A0A2Y9T9K2
uniprot id: A0A2Y9TBJ2
uniprot id: A0A2Y9TDA6
uniprot id: A0A455B8V5
uniprot id: A0A455BN77
uniprot id: A0A455BND1
names: Similarity
messages: Belongs to the CEP63 family.

9755:PDE2A
gene id: 9755:PDE2A
uniprot id: A0A2Y9EZ05
uniprot id: A0A455C7H2
uniprot id: A0A455C7N2
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9755:LOC102976099
gene id: 9755:LOC102976099
uniprot id: A0A2Y9FHP5
uniprot id: A0A455BMP0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

9755:IFT46
gene id: 9755:IFT46
uniprot id: A0A2Y9FIP6
uniprot id: A0A2Y9FIU0
uniprot id: A0A455C6N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFT46 family.
messages: cilium
messages: cilium basal body

9755:LMX1B
gene id: 9755:LMX1B
uniprot id: A0A455BQK3
names: Subcellular Location Annotation
messages: Nucleus

9755:APEX2
gene id: 9755:APEX2
uniprot id: A0A2Y9FFF4
uniprot id: A0A2Y9FHG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Cytoplasm
messages: Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
messages: Mitochondrion
messages: Nucleus
messages: Probably binds two magnesium or manganese ions per subunit.

9755:NDUFB3
gene id: 9755:NDUFB3
uniprot id: A0A2Y9ESQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB3 subunit family.
messages: Mitochondrion inner membrane

9755:DUOX1
gene id: 9755:DUOX1
uniprot id: A0A2Y9S1W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.
messages: In the N-terminal section; belongs to the peroxidase family.
messages: Membrane

9755:NDUFA2
gene id: 9755:NDUFA2
uniprot id: A0A2Y9ES28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA2 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9755:FGF14
gene id: 9755:FGF14
uniprot id: A0A2Y9SJX9
uniprot id: A0A2Y9SNB8
uniprot id: A0A2Y9SR87
uniprot id: A0A455C0L6
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9755:SCNN1D
gene id: 9755:SCNN1D
uniprot id: A0A2Y9SXW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
messages: Membrane

9755:LOC112062576
gene id: 9755:LOC112062576
uniprot id: A0A2Y9S3G2
names: Similarity
messages: Belongs to the histone H2B family.

9755:AMHR2
gene id: 9755:AMHR2
uniprot id: A0A2Y9FKP8
uniprot id: A0A2Y9SMW1
uniprot id: A0A455BEE3
uniprot id: A0A455BGT4
uniprot id: A0A455BTE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane
messages: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.

9755:UGGT1
gene id: 9755:UGGT1
uniprot id: A0A2Y9FN01
uniprot id: A0A2Y9FQD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 8 family.
messages: Endoplasmic reticulum lumen

9755:NDUFAF1
gene id: 9755:NDUFAF1
uniprot id: A0A2Y9EZC9
names: Function
names: Similarity
messages: As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.
messages: Belongs to the CIA30 family.

9755:LOC102992353
gene id: 9755:LOC102992353
uniprot id: A0A455ANH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

9755:LOC102973390
gene id: 9755:LOC102973390
uniprot id: A0A2Y9F7T4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:AHCYL2
gene id: 9755:AHCYL2
uniprot id: A0A2Y9SZU6
uniprot id: A0A2Y9SZW6
uniprot id: A0A2Y9T3P6
uniprot id: A0A2Y9T7V7
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

9755:KCNJ15
gene id: 9755:KCNJ15
uniprot id: A0A2Y9EYQ2
uniprot id: A0A2Y9F079
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

9755:ZSCAN2
gene id: 9755:ZSCAN2
uniprot id: A0A455C4A1
names: Subcellular Location Annotation
messages: Nucleus

9755:STAM2
gene id: 9755:STAM2
uniprot id: A0A2Y9SH70
uniprot id: A0A2Y9SHU2
uniprot id: A0A2Y9SKU9
uniprot id: A0A2Y9SQL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Early endosome membrane
messages: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes.

9755:MRPL32
gene id: 9755:MRPL32
uniprot id: A0A2Y9FL26
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

9755:SLC26A7
gene id: 9755:SLC26A7
uniprot id: A0A2Y9RYZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

9755:SLCO2A1
gene id: 9755:SLCO2A1
uniprot id: A0A2Y9TBN1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:EPOR
gene id: 9755:EPOR
uniprot id: A0A2Y9ERB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Forms homodimers on EPO stimulation.
messages: Membrane
messages: Receptor for erythropoietin.

9755:TENM1
gene id: 9755:TENM1
uniprot id: A0A2Y9SZ71
uniprot id: A0A455AP75
uniprot id: A0A455AP83
uniprot id: A0A455APG6
uniprot id: A0A455AQV2
uniprot id: A0A455ARB9
uniprot id: A0A455B356
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:LMX1A
gene id: 9755:LMX1A
uniprot id: A0A455BJ34
names: Subcellular Location Annotation
messages: Nucleus

9755:SLC12A4
gene id: 9755:SLC12A4
uniprot id: A0A2Y9ST10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

9755:PGK1
gene id: 9755:PGK1
uniprot id: A0A2Y9FD52
uniprot id: A0A2Y9TB21
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

9755:CEP19
gene id: 9755:CEP19
uniprot id: A0A2Y9F5X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP19 family.
messages: centriole
messages: cilium basal body
messages: spindle pole

9755:INHBA
gene id: 9755:INHBA
uniprot id: A0A2Y9FKK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

9755:PDE9A
gene id: 9755:PDE9A
uniprot id: A0A455BN19
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9755:LOC102990948
gene id: 9755:LOC102990948
uniprot id: A0A2Y9EH63
uniprot id: A0A455BVK1
uniprot id: A0A455BVK6
uniprot id: A0A455BVK9
uniprot id: A0A455BVL0
uniprot id: A0A455BW85
uniprot id: A0A455BW90
uniprot id: A0A455BZ20
uniprot id: A0A455C980
uniprot id: A0A455C983
names: Similarity
messages: Belongs to the adenylate kinase family.

9755:LOC102995190
gene id: 9755:LOC102995190
uniprot id: A0A2Y9EW10
names: Similarity
messages: Belongs to the heat shock protein 70 family.

9755:HNF4G
gene id: 9755:HNF4G
uniprot id: A0A2Y9FD07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Nucleus

9755:PHOX2B
gene id: 9755:PHOX2B
uniprot id: A0A2Y9TJS7
names: Subcellular Location Annotation
messages: Nucleus

9755:PLPPR2
gene id: 9755:PLPPR2
uniprot id: A0A2Y9EPQ5
uniprot id: A0A2Y9EPT8
uniprot id: A0A2Y9ER56
uniprot id: A0A2Y9TJA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

9755:MYOZ2
gene id: 9755:MYOZ2
uniprot id: A0A2Y9ETD3
uniprot id: A0A455BH22
names: Similarity
messages: Belongs to the myozenin family.

9755:GRPEL2
gene id: 9755:GRPEL2
uniprot id: A0A2Y9FXD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

9755:TGFA
gene id: 9755:TGFA
uniprot id: A0A2Y9FR72
uniprot id: A0A2Y9TGL2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:WNT9A
gene id: 9755:WNT9A
uniprot id: A0A2Y9S8E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9755:CLASP2
gene id: 9755:CLASP2
uniprot id: A0A2Y9FJV7
uniprot id: A0A2Y9FL70
names: Subcellular Location Annotation
messages: kinetochore

9755:TFCP2L1
gene id: 9755:TFCP2L1
uniprot id: A0A2Y9RZZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

9755:DPF3
gene id: 9755:DPF3
uniprot id: A0A455BSG0
uniprot id: A0A455BT63
names: Similarity
messages: Belongs to the requiem/DPF family.

9755:PRKAR2B
gene id: 9755:PRKAR2B
uniprot id: A0A2Y9RZH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

9755:LOC102989171
gene id: 9755:LOC102989171
uniprot id: A0A2Y9FMJ7
names: Similarity
messages: Belongs to the cytochrome P450 family.

9755:DR1
gene id: 9755:DR1
uniprot id: A0A2Y9FGB1
uniprot id: A0A2Y9FGK3
names: Similarity
messages: Belongs to the NC2 beta/DR1 family.

9755:TREH
gene id: 9755:TREH
uniprot id: A0A2Y9FUQ5
names: Similarity
messages: Belongs to the glycosyl hydrolase 37 family.

9755:FTO
gene id: 9755:FTO
uniprot id: A0A2Y9SRG2
uniprot id: A0A2Y9SW64
uniprot id: A0A2Y9SYD6
uniprot id: A0A455ABU6
uniprot id: A0A455ABV1
uniprot id: A0A455AD05
uniprot id: A0A455ADZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fto family.
messages: Cytoplasm
messages: Nucleus speckle

9755:MYT1L
gene id: 9755:MYT1L
uniprot id: A0A2Y9S7N4
uniprot id: A0A2Y9SEC5
uniprot id: A0A2Y9SFP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYT1 family.
messages: Nucleus

9755:HGD
gene id: 9755:HGD
uniprot id: A0A2Y9ELL4
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

9755:NOTCH1
gene id: 9755:NOTCH1
uniprot id: A0A2Y9SVH2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

9755:LAMA5
gene id: 9755:LAMA5
uniprot id: A0A2Y9T1A3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

9755:TCTA
gene id: 9755:TCTA
uniprot id: A0A2Y9FVP1
uniprot id: A0A2Y9SST5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCTA family.
messages: May be required for cellular fusion during osteoclastogenesis.
messages: Membrane

9755:BRAF
gene id: 9755:BRAF
uniprot id: A0A2Y9SYF0
uniprot id: A0A2Y9SYF4
uniprot id: A0A2Y9SZY4
uniprot id: A0A455B935
uniprot id: A0A455B9W2
uniprot id: A0A455BBZ2
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

9755:LOC102988557
gene id: 9755:LOC102988557
uniprot id: A0A2Y9FBS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:PPP1R16B
gene id: 9755:PPP1R16B
uniprot id: A0A2Y9T1T9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9755:EVX2
gene id: 9755:EVX2
uniprot id: A0A2Y9SNL4
names: Subcellular Location Annotation
messages: Nucleus

9755:MRPS27
gene id: 9755:MRPS27
uniprot id: A0A2Y9S9X0
uniprot id: A0A455BY99
names: Subcellular Location Annotation
messages: Mitochondrion

9755:RHOT1
gene id: 9755:RHOT1
uniprot id: A0A2Y9EQ53
uniprot id: A0A2Y9SXL5
uniprot id: A0A2Y9SXM0
uniprot id: A0A2Y9SZ17
uniprot id: A0A2Y9SZ23
uniprot id: A0A2Y9T1K5
uniprot id: A0A2Y9T3L6
uniprot id: A0A2Y9T3M2
uniprot id: A0A2Y9T5L4
uniprot id: A0A2Y9T5L8
uniprot id: A0A455BXW3
uniprot id: A0A455BXW7
uniprot id: A0A455BXX2
uniprot id: A0A455C1M9
uniprot id: A0A455C1N6
uniprot id: A0A455CA08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking.
messages: Mitochondrion outer membrane

9755:IL18RAP
gene id: 9755:IL18RAP
uniprot id: A0A2Y9ETF6
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

9755:SDC3
gene id: 9755:SDC3
uniprot id: A0A2Y9FS71
uniprot id: A0A455B2U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

9755:BLOC1S5
gene id: 9755:BLOC1S5
uniprot id: A0A2Y9SGL3
names: Similarity
messages: Belongs to the BLOC1S5 family.

9755:SIGIRR
gene id: 9755:SIGIRR
uniprot id: A0A2Y9FCR9
uniprot id: A0A455AGX8
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

9755:LOC112066353
gene id: 9755:LOC112066353
uniprot id: A0A2Y9FCJ9
uniprot id: A0A2Y9FCR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the leptin family.
messages: Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, increases basal metabolism, influences reproductive function, regulates pancreatic beta-cell function and insulin secretion, is pro-angiogenic for endothelial cell and affects innate and adaptive immunity. In the arcuate nucleus of the hypothalamus, activates by depolarization POMC neurons inducing FOS and SOCS3 expression to release anorexigenic peptides and inhibits by hyperpolarization NPY neurons inducing SOCS3 with a consequent reduction on release of orexigenic peptides. In addition to its known satiety inducing effect, has a modulatory role in nutrient absorption. In the intestine, reduces glucose absorption by enterocytes by activating PKC and leading to a sequential activation of p38, PI3K and ERK signaling pathways which exerts an inhibitory effect on glucose absorption. Acts as a growth factor on certain tissues, through the activation of different signaling pathways increases expression of genes involved in cell cycle regulation such as CCND1, via JAK2-STAT3 pathway, or VEGFA, via MAPK1/3 and PI3K-AKT1 pathways. May also play an apoptotic role via JAK2-STAT3 pathway and up-regulation of BIRC5 expression. Pro-angiogenic, has mitogenic activity on vascular endothelial cells and plays a role in matrix remodeling by regulating the expression of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs). In innate immunity, modulates the activity and function of neutrophils by in…
messages: Secreted

9755:HEBP1
gene id: 9755:HEBP1
uniprot id: A0A2Y9FKU2
uniprot id: A0A455BCY6
uniprot id: A0A455BSK3
names: Similarity
messages: Belongs to the HEBP family.

9755:LOC102994795
gene id: 9755:LOC102994795
uniprot id: A0A2Y9EYS3
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 2 family.

9755:MYOG
gene id: 9755:MYOG
uniprot id: A0A2Y9FF75
names: Subcellular Location Annotation
messages: Nucleus

9755:CARNMT1
gene id: 9755:CARNMT1
uniprot id: A0A2Y9EW55
uniprot id: A0A2Y9EXH1
uniprot id: A0A455C0Z6
names: Similarity
messages: Belongs to the carnosine N-methyltransferase family.

9755:VEPH1
gene id: 9755:VEPH1
uniprot id: A0A2Y9EQM5
uniprot id: A0A2Y9ERL2
names: Similarity
messages: Belongs to the MELT/VEPH family.

9755:CXCL8
gene id: 9755:CXCL8
uniprot id: A0A2Y9FM29
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Homodimer.
messages: Secreted

9755:PTPN18
gene id: 9755:PTPN18
uniprot id: A0A2Y9S2Q3
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 4 subfamily.

9755:MED8
gene id: 9755:MED8
uniprot id: A0A2Y9F8Z7
uniprot id: A0A2Y9F904
uniprot id: A0A2Y9F9D8
uniprot id: A0A455AX71
uniprot id: A0A455BAX4
uniprot id: A0A455BAX9
uniprot id: A0A455BAZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 8 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

9755:LOC102988802
gene id: 9755:LOC102988802
uniprot id: A0A2Y9EVI7
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

9755:TACC1
gene id: 9755:TACC1
uniprot id: A0A2Y9FNE2
uniprot id: A0A2Y9FNL1
uniprot id: A0A2Y9FNX3
uniprot id: A0A2Y9TAL9
uniprot id: A0A455ANF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

9755:UMODL1
gene id: 9755:UMODL1
uniprot id: A0A455BYX1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:MBLAC1
gene id: 9755:MBLAC1
uniprot id: A0A2Y9SL82
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

9755:MAP1LC3A
gene id: 9755:MAP1LC3A
uniprot id: A0A2Y9T1I1
names: Similarity
messages: Belongs to the ATG8 family.

9755:CLCN6
gene id: 9755:CLCN6
uniprot id: A0A455B4B9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:AS3MT
gene id: 9755:AS3MT
uniprot id: A0A455ANX6
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

9755:QNG1
gene id: 9755:QNG1
uniprot id: A0A2Y9EHJ3
uniprot id: A0A2Y9TEE2
names: Function
names: Similarity
messages: Belongs to the QNG1 protein family.
messages: Catalyzes the hydrolysis of queuosine 5'-phosphate, releasing the nucleobase queuine (q). Is required for salvage of queuine from exogenous queuosine (Q) that is imported and then converted to queuosine 5'-phosphate intracellularly.

9755:FZD8
gene id: 9755:FZD8
uniprot id: A0A2Y9T3B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

9755:LOC102993463
gene id: 9755:LOC102993463
uniprot id: A0A2Y9S7E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:EID3
gene id: 9755:EID3
uniprot id: A0A2Y9EKF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE4 family.
messages: Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
messages: Component of the SMC5-SMC6 complex.
messages: Nucleus
messages: telomere

9755:FAM131B
gene id: 9755:FAM131B
uniprot id: A0A2Y9TAZ3
uniprot id: A0A455BNL8
names: Similarity
messages: Belongs to the FAM131 family.

9755:TUBB
gene id: 9755:TUBB
uniprot id: A0A2Y9EP82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

9755:GPSM2
gene id: 9755:GPSM2
uniprot id: A0A2Y9SDP2
uniprot id: A0A2Y9SGP5
names: Similarity
messages: Belongs to the GPSM family.

9755:LOC102982135
gene id: 9755:LOC102982135
uniprot id: A0A455B7D3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:AQP8
gene id: 9755:AQP8
uniprot id: A0A2Y9EN04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

9755:TNFSF4
gene id: 9755:TNFSF4
uniprot id: A0A2Y9FA66
names: Similarity
messages: Belongs to the tumor necrosis factor family.

9755:MGAT2
gene id: 9755:MGAT2
uniprot id: A0A2Y9EPN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 16 (GT16) protein family.
messages: Golgi apparatus membrane
messages: Membrane

9755:SLC44A4
gene id: 9755:SLC44A4
uniprot id: A0A2Y9EWL6
uniprot id: A0A2Y9EX27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

9755:FZD1
gene id: 9755:FZD1
uniprot id: A0A2Y9T066
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:LOC102979737
gene id: 9755:LOC102979737
uniprot id: A0A2Y9EK01
names: Similarity
messages: Belongs to the globin family.

9755:IARS1
gene id: 9755:IARS1
uniprot id: A0A2Y9S328
uniprot id: A0A2Y9S333
uniprot id: A0A2Y9S9I4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9755:CANT1
gene id: 9755:CANT1
uniprot id: A0A2Y9ERD3
uniprot id: A0A2Y9TDT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apyrase family.
messages: Promotes integrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells.
messages: extracellular matrix

9755:FMO1
gene id: 9755:FMO1
uniprot id: A0A2Y9FGN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:CD79A
gene id: 9755:CD79A
uniprot id: A0A2Y9EGG1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9755:AKAP3
gene id: 9755:AKAP3
uniprot id: A0A2Y9EK80
names: Similarity
messages: Belongs to the AKAP110 family.

9755:SLC12A7
gene id: 9755:SLC12A7
uniprot id: A0A2Y9SHL8
uniprot id: A0A2Y9SKJ0
uniprot id: A0A455BHZ3
uniprot id: A0A455BIL5
uniprot id: A0A455BXP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

9755:AHCYL1
gene id: 9755:AHCYL1
uniprot id: A0A2Y9EPD3
uniprot id: A0A2Y9EQU5
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

9755:FGA
gene id: 9755:FGA
uniprot id: A0A2Y9F8B3
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

9755:GALK2
gene id: 9755:GALK2
uniprot id: A0A2Y9S264
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

9755:TRNAU1AP
gene id: 9755:TRNAU1AP
uniprot id: A0A2Y9EF17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TRSPAP family.
messages: Cytoplasm
messages: Involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins. Stabilizes the SECISBP2, EEFSEC and tRNA(Sec) complex. May be involved in the methylation of tRNA(Sec). Enhances efficiency of selenoproteins synthesis.
messages: Nucleus

9755:PARP6
gene id: 9755:PARP6
uniprot id: A0A455BSM2
names: Similarity
messages: Belongs to the ARTD/PARP family.

9755:TNR
gene id: 9755:TNR
uniprot id: A0A2Y9FBD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family.
messages: extracellular matrix

9755:COL4A6
gene id: 9755:COL4A6
uniprot id: A0A2Y9T4V1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

9755:HSDL2
gene id: 9755:HSDL2
uniprot id: A0A2Y9EPW7
uniprot id: A0A2Y9ERE1
names: Subcellular Location Annotation
messages: Peroxisome

9755:RAX
gene id: 9755:RAX
uniprot id: A0A2Y9TKL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

9755:LIPI
gene id: 9755:LIPI
uniprot id: A0A2Y9ECT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

9755:LOC102990281
gene id: 9755:LOC102990281
uniprot id: A0A2Y9EY68
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:CALHM3
gene id: 9755:CALHM3
uniprot id: A0A455ANH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

9755:HDAC4
gene id: 9755:HDAC4
uniprot id: A0A455B500
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

9755:ST6GAL1
gene id: 9755:ST6GAL1
uniprot id: A0A2Y9SWK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9755:FHIP1B
gene id: 9755:FHIP1B
uniprot id: A0A455C7B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIP family.
messages: Membrane

9755:TAFA4
gene id: 9755:TAFA4
uniprot id: A0A2Y9ENC7
names: Similarity
messages: Belongs to the TAFA family.

9755:ENTPD7
gene id: 9755:ENTPD7
uniprot id: A0A2Y9EVP2
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

9755:CHMP3
gene id: 9755:CHMP3
uniprot id: A0A2Y9T9W1
names: Similarity
messages: Belongs to the SNF7 family.

9755:TMED1
gene id: 9755:TMED1
uniprot id: A0A2Y9ERG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

9755:TFAP2B
gene id: 9755:TFAP2B
uniprot id: A0A2Y9EFL9
uniprot id: A0A2Y9EGA8
names: Similarity
messages: Belongs to the AP-2 family.

9755:GJA5
gene id: 9755:GJA5
uniprot id: A0A455B7E0
uniprot id: A0A455B9R8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9755:KLHL3
gene id: 9755:KLHL3
uniprot id: A0A2Y9SR59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KLHL3 family.
messages: cytoskeleton
messages: cytosol

9755:TLE2
gene id: 9755:TLE2
uniprot id: A0A2Y9TGE9
uniprot id: A0A2Y9TJP9
uniprot id: A0A455CBE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

9755:VPS28
gene id: 9755:VPS28
uniprot id: A0A2Y9ELD6
uniprot id: A0A2Y9ELZ1
names: Function
names: Similarity
messages: Belongs to the VPS28 family.
messages: Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.

9755:LOC114484743
gene id: 9755:LOC114484743
uniprot id: A0A455AS72
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

9755:GBF1
gene id: 9755:GBF1
uniprot id: A0A2Y9SKW7
uniprot id: A0A455ALK7
uniprot id: A0A455ALL1
uniprot id: A0A455ALV4
uniprot id: A0A455ALV8
uniprot id: A0A455AND0
uniprot id: A0A455AND6
uniprot id: A0A455ANM8
uniprot id: A0A455ANN2
uniprot id: A0A455B0B6
uniprot id: A0A455B0C5
names: Subcellular Location Annotation
messages: Golgi apparatus

9755:SLC1A4
gene id: 9755:SLC1A4
uniprot id: A0A455BVB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

9755:LOC102984445
gene id: 9755:LOC102984445
uniprot id: A0A2Y9FII1
names: Similarity
messages: Belongs to the MS4A family.

9755:CFDP1
gene id: 9755:CFDP1
uniprot id: A0A2Y9SQV0
uniprot id: A0A455AB23
names: Function
names: Subcellular Location Annotation
messages: May play a role during embryogenesis.
messages: kinetochore

9755:OCLN
gene id: 9755:OCLN
uniprot id: A0A2Y9FSZ7
uniprot id: A0A2Y9FUZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
messages: Membrane
messages: tight junction

9755:SEMA4C
gene id: 9755:SEMA4C
uniprot id: A0A2Y9TC56
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:SOGA1
gene id: 9755:SOGA1
uniprot id: A0A2Y9F875
uniprot id: A0A455BYX4
uniprot id: A0A455BYY0
names: Similarity
messages: Belongs to the SOGA family.

9755:PHF5A
gene id: 9755:PHF5A
uniprot id: A0A455BBX7
uniprot id: A0A455BRH6
names: Similarity
messages: Belongs to the PHF5 family.

9755:CISD1
gene id: 9755:CISD1
uniprot id: A0A2Y9ERG6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CISD protein family. CISD2 subfamily.
messages: Binds 1 [2Fe-2S] cluster.
messages: Endoplasmic reticulum membrane
messages: Homodimer.
messages: Mitochondrion outer membrane
messages: Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy.

9755:TPM4
gene id: 9755:TPM4
uniprot id: A0A2Y9EMC7
uniprot id: A0A2Y9ENE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

9755:KIF16B
gene id: 9755:KIF16B
uniprot id: A0A2Y9SL52
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9755:S100B
gene id: 9755:S100B
uniprot id: A0A2Y9FKI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the S-100 family.
messages: Cytoplasm
messages: Nucleus
messages: Secreted

9755:FAM13B
gene id: 9755:FAM13B
uniprot id: A0A2Y9SB22
uniprot id: A0A2Y9SB37
uniprot id: A0A2Y9SB54
uniprot id: A0A2Y9SBR7
uniprot id: A0A2Y9SHP4
uniprot id: A0A2Y9SHP7
uniprot id: A0A2Y9SHS7
uniprot id: A0A2Y9SJA6
uniprot id: A0A2Y9SJF2
names: Similarity
messages: Belongs to the FAM13 family.

9755:SLC39A14
gene id: 9755:SLC39A14
uniprot id: A0A2Y9FN66
uniprot id: A0A2Y9FP62
uniprot id: A0A2Y9TA23
uniprot id: A0A455C212
names: Subcellular Location Annotation
messages: Membrane

9755:MEIS3
gene id: 9755:MEIS3
uniprot id: A0A2Y9EI29
uniprot id: A0A2Y9EIQ5
uniprot id: A0A2Y9EJB5
uniprot id: A0A2Y9EJE9
uniprot id: A0A455ACX4
uniprot id: A0A455AQ54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

9755:GPLD1
gene id: 9755:GPLD1
uniprot id: A0A455AF88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPLD1 family.
messages: Secreted

9755:GPBP1
gene id: 9755:GPBP1
uniprot id: A0A2Y9EZS3
uniprot id: A0A2Y9F043
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vasculin family.
messages: Nucleus

9755:NIP7
gene id: 9755:NIP7
uniprot id: A0A2Y9FRC0
uniprot id: A0A2Y9FRC7
uniprot id: A0A2Y9FRG2
uniprot id: A0A455ABN1
uniprot id: A0A455ANI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NIP7 family.
messages: Interacts with pre-ribosome complex.
messages: Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.
messages: nucleolus

9755:MUSTN1
gene id: 9755:MUSTN1
uniprot id: A0A2Y9FA70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MUSTANG family.
messages: Nucleus

9755:PLEKHA3
gene id: 9755:PLEKHA3
uniprot id: A0A2Y9SI98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sesquipedalian family.
messages: Early endosome
messages: Forms homodimers and heterodimers with PHETA. Interacts with OCRL and INPP5B.
messages: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
messages: Recycling endosome
messages: clathrin-coated vesicle
messages: trans-Golgi network

9755:NQO1
gene id: 9755:NQO1
uniprot id: A0A455ADI1
names: Similarity
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family.

9755:RAB3IP
gene id: 9755:RAB3IP
uniprot id: A0A2Y9SJX3
uniprot id: A0A2Y9SSK4
uniprot id: A0A455BBP4
names: Similarity
messages: Belongs to the SEC2 family.

9755:LOC102988542
gene id: 9755:LOC102988542
uniprot id: A0A2Y9TJF9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:TRAM2
gene id: 9755:TRAM2
uniprot id: A0A2Y9SM75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

9755:EIF5A
gene id: 9755:EIF5A
uniprot id: A0A2Y9EFS4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.

9755:BRMS1L
gene id: 9755:BRMS1L
uniprot id: A0A2Y9S671
uniprot id: A0A2Y9S9W2
names: Subcellular Location Annotation
messages: Nucleus

9755:MTFMT
gene id: 9755:MTFMT
uniprot id: A0A2Y9T183
names: Similarity
messages: Belongs to the Fmt family.

9755:LOC102995829
gene id: 9755:LOC102995829
uniprot id: A0A2Y9F0R6
names: Similarity
messages: Belongs to the folate receptor family.

9755:GUCY1A2
gene id: 9755:GUCY1A2
uniprot id: A0A2Y9RXQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

9755:MPP1
gene id: 9755:MPP1
uniprot id: A0A2Y9FFC7
names: Function
names: Subcellular Location Annotation
messages: Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity.
messages: stereocilium

9755:AP4M1
gene id: 9755:AP4M1
uniprot id: A0A2Y9F077
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

9755:NDUFB9
gene id: 9755:NDUFB9
uniprot id: A0A2Y9EUZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I LYR family.
messages: Mammalian complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9755:ANO3
gene id: 9755:ANO3
uniprot id: A0A2Y9SGC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Membrane

9755:PPM1E
gene id: 9755:PPM1E
uniprot id: A0A2Y9F9P2
names: Similarity
messages: Belongs to the PP2C family.

9755:REXO4
gene id: 9755:REXO4
uniprot id: A0A2Y9EYV3
names: Similarity
messages: Belongs to the REXO4 family.

9755:STC2
gene id: 9755:STC2
uniprot id: A0A2Y9F335
uniprot id: A0A455C9M3
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.

9755:ABI1
gene id: 9755:ABI1
uniprot id: A0A2Y9F212
uniprot id: A0A2Y9F216
uniprot id: A0A2Y9F283
uniprot id: A0A2Y9F287
uniprot id: A0A2Y9F2K5
uniprot id: A0A2Y9F2K7
uniprot id: A0A2Y9F3D7
uniprot id: A0A2Y9F3Z8
uniprot id: A0A2Y9F404
uniprot id: A0A2Y9T766
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABI family.
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

9755:SLC46A2
gene id: 9755:SLC46A2
uniprot id: A0A2Y9FCS3
names: Subcellular Location Annotation
messages: Membrane

9755:ERLIN1
gene id: 9755:ERLIN1
uniprot id: A0A2Y9F996
uniprot id: A0A455B0H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the band 7/mec-2 family.
messages: Endoplasmic reticulum membrane
messages: Mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway.
messages: Membrane

9755:SYBU
gene id: 9755:SYBU
uniprot id: A0A455C595
uniprot id: A0A455C5A3
uniprot id: A0A455C5J3
uniprot id: A0A455C5J7
uniprot id: A0A455C5K2
uniprot id: A0A455C6A4
uniprot id: A0A455C6B0
uniprot id: A0A455CBK8
names: Subcellular Location Annotation
messages: Membrane

9755:TEC
gene id: 9755:TEC
uniprot id: A0A2Y9THL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

9755:LOC112063641
gene id: 9755:LOC112063641
uniprot id: A0A2Y9S8K3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:WDR55
gene id: 9755:WDR55
uniprot id: A0A2Y9ETJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR55 family.
messages: Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis.
messages: nucleolus

9755:CCR5
gene id: 9755:CCR5
uniprot id: A0A2Y9SVD4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9755:CMC2
gene id: 9755:CMC2
uniprot id: A0A2Y9SVR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion

9755:SLAIN1
gene id: 9755:SLAIN1
uniprot id: A0A2Y9F9D5
uniprot id: A0A2Y9F9Y7
uniprot id: A0A2Y9STE8
names: Similarity
messages: Belongs to the SLAIN motif-containing family.

9755:SH3RF2
gene id: 9755:SH3RF2
uniprot id: A0A2Y9SWM0
uniprot id: A0A455BK64
uniprot id: A0A455BMP6
names: Similarity
messages: Belongs to the SH3RF family.

9755:TCEA1
gene id: 9755:TCEA1
uniprot id: A0A2Y9ENW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

9755:EEF1B2
gene id: 9755:EEF1B2
uniprot id: A0A2Y9EZF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: EF-1 is composed of 4 subunits: alpha, beta, delta, and gamma.
messages: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.

9755:GSN
gene id: 9755:GSN
uniprot id: A0A2Y9FI53
uniprot id: A0A2Y9FIA5
uniprot id: A0A455BKV2
uniprot id: A0A455BND2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the villin/gelsolin family.
messages: Binds to actin and to fibronectin. Identified in a complex composed of ACTA1, COBL, GSN and TMSB4X. Interacts with the inactive form of EIF2AK2/PKR.
messages: Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis.
messages: cytoskeleton

9755:PRND
gene id: 9755:PRND
uniprot id: A0A2Y9FHK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prion family.
messages: Cell membrane
messages: Membrane

9755:EGR2
gene id: 9755:EGR2
uniprot id: A0A2Y9RY94
uniprot id: A0A455AP62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus

9755:AGXT
gene id: 9755:AGXT
uniprot id: A0A2Y9FQX6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: Peroxisome

9755:GCHFR
gene id: 9755:GCHFR
uniprot id: A0A2Y9EZA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GFRP family.
messages: Membrane
messages: Nucleus membrane
messages: cytosol

9755:TRPM1
gene id: 9755:TRPM1
uniprot id: A0A455BQ26
names: Subcellular Location Annotation
messages: Membrane

9755:PHACTR3
gene id: 9755:PHACTR3
uniprot id: A0A455C2P6
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

9755:NR3C1
gene id: 9755:NR3C1
uniprot id: A0A2Y9SPF1
uniprot id: A0A2Y9SXQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Mitochondrion
messages: Nucleus
messages: centrosome
messages: spindle

9755:PALS2
gene id: 9755:PALS2
uniprot id: A0A455BAQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane

9755:RSPO2
gene id: 9755:RSPO2
uniprot id: A0A2Y9EII2
uniprot id: A0A2Y9EKK6
uniprot id: A0A2Y9T5X0
names: Similarity
messages: Belongs to the R-spondin family.

9755:NUP210L
gene id: 9755:NUP210L
uniprot id: A0A455B9G9
names: Similarity
messages: Belongs to the NUP210 family.

9755:POMT1
gene id: 9755:POMT1
uniprot id: A0A2Y9T085
uniprot id: A0A455BWF4
uniprot id: A0A455BZZ7
uniprot id: A0A455C9K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

9755:RPL34
gene id: 9755:RPL34
uniprot id: A0A2Y9FFJ5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

9755:LOC112063883
gene id: 9755:LOC112063883
uniprot id: A0A2Y9SHF5
names: Similarity
messages: Belongs to the intermediate filament family.

9755:IL10
gene id: 9755:IL10
uniprot id: A0A2Y9EEH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-10 family.
messages: Homodimer. Interacts with IL10RA and IL10RB.
messages: Immune regulatory cytokine.
messages: Secreted

9755:LOC102985833
gene id: 9755:LOC102985833
uniprot id: A0A2Y9F4T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9755:SLC14A2
gene id: 9755:SLC14A2
uniprot id: A0A2Y9F4Q4
uniprot id: A0A2Y9F6D0
uniprot id: A0A2Y9TCN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

9755:UNC13A
gene id: 9755:UNC13A
uniprot id: A0A2Y9F9P1
names: Subcellular Location Annotation
messages: Cytoplasm

9755:ENO4
gene id: 9755:ENO4
uniprot id: A0A2Y9FLG1
names: Similarity
messages: Belongs to the enolase family.

9755:CAPN10
gene id: 9755:CAPN10
uniprot id: A0A2Y9SSP1
uniprot id: A0A455ARK1
names: Similarity
messages: Belongs to the peptidase C2 family.

9755:CENPS
gene id: 9755:CENPS
uniprot id: A0A2Y9F6T6
names: Similarity
messages: Belongs to the TAF9 family. CENP-S/MHF1 subfamily.

9755:GPRC5C
gene id: 9755:GPRC5C
uniprot id: A0A2Y9ECP8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9755:LOC102996701
gene id: 9755:LOC102996701
uniprot id: A0A2Y9FFQ9
names: Similarity
messages: Belongs to the FBPase class 1 family.

9755:TADA2A
gene id: 9755:TADA2A
uniprot id: A0A2Y9T1X6
names: Subcellular Location Annotation
messages: Nucleus

9755:LOC102988322
gene id: 9755:LOC102988322
uniprot id: A0A2Y9TDT5
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

9755:FAM91A1
gene id: 9755:FAM91A1
uniprot id: A0A2Y9F3H5
names: Similarity
messages: Belongs to the FAM91 family.

9755:PIGZ
gene id: 9755:PIGZ
uniprot id: A0A2Y9F535
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:LHX5
gene id: 9755:LHX5
uniprot id: A0A2Y9EL74
names: Subcellular Location Annotation
messages: Nucleus

9755:LOC114483853
gene id: 9755:LOC114483853
uniprot id: A0A2Y9RXD9
names: Similarity
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.

9755:ETV6
gene id: 9755:ETV6
uniprot id: A0A2Y9F349
uniprot id: A0A2Y9F4N5
uniprot id: A0A455BDJ4
uniprot id: A0A455BSH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9755:EIF3A
gene id: 9755:EIF3A
uniprot id: A0A2Y9EZX3
uniprot id: A0A455AKZ8
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit A family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3L and EIF3K. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with EIF4G1. Also interacts with KRT7 and PIWIL2.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.

9755:PHKA1
gene id: 9755:PHKA1
uniprot id: A0A2Y9T958
uniprot id: A0A2Y9TAP5
uniprot id: A0A2Y9TDB3
uniprot id: A0A455AQ30
uniprot id: A0A455ARN4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

9755:TRIAP1
gene id: 9755:TRIAP1
uniprot id: A0A2Y9FW26
names: Similarity
messages: Belongs to the TRIAP1/MDM35 family.

9755:INPP4B
gene id: 9755:INPP4B
uniprot id: A0A2Y9F039
names: Similarity
messages: Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

9755:CPD
gene id: 9755:CPD
uniprot id: A0A2Y9SYY3
names: Similarity
messages: Belongs to the peptidase M14 family.

9755:MYMK
gene id: 9755:MYMK
uniprot id: A0A2Y9EXT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Membrane

9755:KIFC2
gene id: 9755:KIFC2
uniprot id: A0A455C457
uniprot id: A0A455C4F4
uniprot id: A0A455C579
uniprot id: A0A455CBC8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9755:CRYGS
gene id: 9755:CRYGS
uniprot id: A0A2Y9FH42
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

9755:MSH6
gene id: 9755:MSH6
uniprot id: A0A2Y9EYL6
uniprot id: A0A2Y9EYR0
uniprot id: A0A2Y9EZR6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).

9755:ATM
gene id: 9755:ATM
uniprot id: A0A2Y9EX57
uniprot id: A0A2Y9EZ30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.
messages: Cytoplasmic vesicle
messages: Nucleus
messages: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B-lymphocytes. After the introduction of DNA breaks by the RAG complex on one immunoglobulin allele, acts by mediating a repositioning of the second allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. Also involved in signal transduction and cell cycle control. May function as a tumor suppressor. Necessary for activation of ABL1 and SAPK. Phosphorylates DYRK2, CHEK2, p53/TP53, FANCD2, NFKBIA, BRCA1, CTIP, nibrin (NBN), TERF1, RAD9, UBQLN4 and DCLRE1C. May play a role in vesicle and/or protein transport. Could play a role in T-cell development, gonad and neurological function. Binds DNA ends. Plays a role in replication-dependent histone mRNA degradation. Phosphorylation of DYRK2 in nucleus in response to genotoxic stress prevents its MDM2-mediated ubiquitination and subsequent proteasome degradation. Phosphorylates ATF2 which stimulates its function in DNA damage response. Phosphorylates ERCC6 which is essential for its chromatin remodeling activity at DNA double-strand breaks.

9755:SDAD1
gene id: 9755:SDAD1
uniprot id: A0A2Y9FJ05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDA1 family.
messages: Required for 60S pre-ribosomal subunits export to the cytoplasm.
messages: nucleolus

9755:ABRAXAS2
gene id: 9755:ABRAXAS2
uniprot id: A0A2Y9EDZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM175 family. Abro1 subfamily.
messages: Nucleus
messages: spindle pole

9755:EIF2A
gene id: 9755:EIF2A
uniprot id: A0A2Y9EEJ4
names: Function
names: Similarity
messages: Belongs to the WD repeat EIF2A family.
messages: Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.

9755:LOC102979567
gene id: 9755:LOC102979567
uniprot id: A0A2Y9FJC0
uniprot id: A0A2Y9FKS3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9755:ARRDC3
gene id: 9755:ARRDC3
uniprot id: A0A2Y9EMU7
uniprot id: A0A2Y9EPC4
names: Similarity
messages: Belongs to the arrestin family.

9755:SLC16A14
gene id: 9755:SLC16A14
uniprot id: A0A2Y9SNW0
uniprot id: A0A455AR10
names: Subcellular Location Annotation
messages: Membrane

9755:ZIC2
gene id: 9755:ZIC2
uniprot id: A0A2Y9SJV5
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

9755:SGMS2
gene id: 9755:SGMS2
uniprot id: A0A2Y9EEY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

9755:CD47
gene id: 9755:CD47
uniprot id: A0A2Y9SFD1
uniprot id: A0A2Y9SJV3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9755:LOC102987244
gene id: 9755:LOC102987244
uniprot id: A0A2Y9FB60
names: Similarity
messages: Belongs to the serpin family.

9755:CCNA2
gene id: 9755:CCNA2
uniprot id: A0A2Y9FDS9
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

9755:LOC102980818
gene id: 9755:LOC102980818
uniprot id: A0A2Y9FP28
uniprot id: A0A455BHE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

9755:ACAD11
gene id: 9755:ACAD11
uniprot id: A0A2Y9T9P2
uniprot id: A0A2Y9TFM6
uniprot id: A0A455BA73
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

9755:LOC114484127
gene id: 9755:LOC114484127
uniprot id: A0A455AQG8
names: Subcellular Location Annotation
messages: Membrane

9755:AK1
gene id: 9755:AK1
uniprot id: A0A455BZX1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK1 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

9755:GFRA4
gene id: 9755:GFRA4
uniprot id: A0A2Y9S2Y1
uniprot id: A0A2Y9SAU6
names: Similarity
messages: Belongs to the GDNFR family.

9755:DMRT2
gene id: 9755:DMRT2
uniprot id: A0A2Y9SVF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

9755:FGD3
gene id: 9755:FGD3
uniprot id: A0A2Y9S6J9
names: Subcellular Location Annotation
messages: cytoskeleton

9755:CALHM1
gene id: 9755:CALHM1
uniprot id: A0A455AM76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

9755:INHBC
gene id: 9755:INHBC
uniprot id: A0A2Y9EKK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

9755:IMMP1L
gene id: 9755:IMMP1L
uniprot id: A0A2Y9F940
uniprot id: A0A2Y9F9H3
uniprot id: A0A455C6H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26 family.
messages: Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO.
messages: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
messages: Mitochondrion inner membrane

9755:MDFIC
gene id: 9755:MDFIC
uniprot id: A0A2Y9T2B2
names: Similarity
messages: Belongs to the MDFI family.

9755:TMTC1
gene id: 9755:TMTC1
uniprot id: A0A455BD89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

9755:SRFBP1
gene id: 9755:SRFBP1
uniprot id: A0A2Y9F6W8
uniprot id: A0A455BYW1
names: Function
names: Subunit
messages: Interacts with SRF. Forms complexes with SRF and SRF cofactors ARID2, MYOCD and NKX2-5. Interacts with the N-terminus of SLC2A4.
messages: May be involved in regulating transcriptional activation of cardiac genes during the aging process. May play a role in biosynthesis and/or processing of SLC2A4 in adipose cells.

9755:MAP3K13
gene id: 9755:MAP3K13
uniprot id: A0A455BV00
names: Function
names: Similarity
messages: Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7.
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

9755:PTPRA
gene id: 9755:PTPRA
uniprot id: A0A2Y9FQJ6
uniprot id: A0A2Y9S2W9
uniprot id: A0A2Y9SAW7
uniprot id: A0A455C6G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 4 subfamily.
messages: Cell membrane
messages: Membrane

9755:PSPC1
gene id: 9755:PSPC1
uniprot id: A0A2Y9T0G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PSPC family.
messages: Cytoplasm
messages: Nucleus matrix
messages: Nucleus speckle
messages: nucleolus

9755:EEIG2
gene id: 9755:EEIG2
uniprot id: A0A2Y9SB55
names: Similarity
messages: Belongs to the EEIG family.

9755:DERL1
gene id: 9755:DERL1
uniprot id: A0A2Y9FLS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Membrane

9755:UHRF2
gene id: 9755:UHRF2
uniprot id: A0A2Y9F000
uniprot id: A0A455BLC0
uniprot id: A0A455BLK6
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Multi domain E3 ubiquitin ligase that also plays a role in DNA methylation and histone modifications.
messages: Nucleus
messages: The YDG domain mediates the interaction with histone H3.
messages: The tudor-like regions specifically recognize and bind histone H3 unmethylated at 'Arg-2' (H3R2me0), while the PHD-type zinc finger specifically recognizes and binds histone H3 trimethylated at 'Lys-9' (H3K9me3).

9755:CRYBG2
gene id: 9755:CRYBG2
uniprot id: A0A455B5S4
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

9755:PLBD1
gene id: 9755:PLBD1
uniprot id: A0A2Y9T344
names: Function
names: Similarity
messages: Belongs to the phospholipase B-like family.
messages: Putative phospholipase.

9755:LOC102984825
gene id: 9755:LOC102984825
uniprot id: A0A2Y9SK27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:RPP30
gene id: 9755:RPP30
uniprot id: A0A2Y9FCN2
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

9755:DPEP1
gene id: 9755:DPEP1
uniprot id: A0A2Y9FKT3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
messages: Homodimer; disulfide-linked.
messages: Membrane

9755:LOC102974307
gene id: 9755:LOC102974307
uniprot id: A0A2Y9EVJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

9755:RPS5
gene id: 9755:RPS5
uniprot id: A0A2Y9FJ89
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

9755:AMZ1
gene id: 9755:AMZ1
uniprot id: A0A2Y9SMT0
names: Function
names: Similarity
messages: Belongs to the peptidase M54 family.
messages: Probable zinc metalloprotease.

9755:MAN1A2
gene id: 9755:MAN1A2
uniprot id: A0A2Y9SI19
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

9755:HTRA4
gene id: 9755:HTRA4
uniprot id: A0A2Y9TG28
names: Similarity
messages: Belongs to the peptidase S1C family.

9755:LOC102989412
gene id: 9755:LOC102989412
uniprot id: A0A2Y9FC02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:FAM83G
gene id: 9755:FAM83G
uniprot id: A0A2Y9F4E5
names: Similarity
messages: Belongs to the FAM83 family.

9755:TSR3
gene id: 9755:TSR3
uniprot id: A0A2Y9EDJ5
uniprot id: A0A455C1G5
uniprot id: A0A455C4I3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1248 (Psi1248) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:CDK8
gene id: 9755:CDK8
uniprot id: A0A2Y9SW67
names: Similarity
messages: Belongs to the protein kinase superfamily.

9755:MYOF
gene id: 9755:MYOF
uniprot id: A0A2Y9ER52
uniprot id: A0A2Y9ES66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferlin family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

9755:GPX8
gene id: 9755:GPX8
uniprot id: A0A2Y9FJA4
names: Similarity
messages: Belongs to the glutathione peroxidase family.

9755:RPS8
gene id: 9755:RPS8
uniprot id: A0A2Y9EZ13
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS8 family.

9755:SAXO1
gene id: 9755:SAXO1
uniprot id: A0A2Y9T1F3
names: Similarity
messages: Belongs to the FAM154 family.

9755:HIBCH
gene id: 9755:HIBCH
uniprot id: A0A2Y9EKB4
uniprot id: A0A455AJJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA.
messages: Mitochondrion

9755:SNW1
gene id: 9755:SNW1
uniprot id: A0A455C4R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNW family.
messages: Identified in the spliceosome C complex.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

9755:HMGCR
gene id: 9755:HMGCR
uniprot id: A0A2Y9SFL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMG-CoA reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane

9755:PGM5
gene id: 9755:PGM5
uniprot id: A0A2Y9T3H1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

9755:SLX4
gene id: 9755:SLX4
uniprot id: A0A2Y9F1Q9
names: Similarity
messages: Belongs to the SLX4 family.

9755:MAP3K7
gene id: 9755:MAP3K7
uniprot id: A0A2Y9FLL1
uniprot id: A0A2Y9FM10
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by pro-inflammatory cytokines and in response to physical and chemical stresses, including osmotic stress, oxidative stress, arsenic and ultraviolet light irradiation. Activated by 'Lys-63'-linked polyubiquitination and by autophosphorylation.
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Cytoplasm

9755:LOC102979550
gene id: 9755:LOC102979550
uniprot id: A0A2Y9EG16
names: Caution
names: Similarity
messages: Belongs to the CRISP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:AGPAT2
gene id: 9755:AGPAT2
uniprot id: A0A2Y9SU36
names: Domain
names: Function
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

9755:MYO7A
gene id: 9755:MYO7A
uniprot id: A0A455C5T9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

9755:CD93
gene id: 9755:CD93
uniprot id: A0A2Y9EFH9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:TMEM199
gene id: 9755:TMEM199
uniprot id: A0A2Y9FFJ2
uniprot id: A0A2Y9FFS9
uniprot id: A0A455C3A1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:ATG5
gene id: 9755:ATG5
uniprot id: A0A2Y9EJZ0
uniprot id: A0A2Y9S5Z8
uniprot id: A0A455C3A8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG5 family.
messages: Conjugated with ATG12.
messages: Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control after oxidative damage, and in subsequent cellular longevity. Plays a critical role in multiple aspects of lymphocyte development and is essential for both B and T lymphocyte survival and proliferation. Required for optimal processing and presentation of antigens for MHC II. Involved in the maintenance of axon morphology and membrane structures, as well as in normal adipocyte differentiation. Promotes primary ciliogenesis through removal of OFD1 from centriolar satellites and degradation of IFT20 via the autophagic pathway.
messages: May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. Plays a crucial role in IFN-gamma-induced autophagic cell death by interacting with FADD.
messages: Preautophagosomal structure membrane

9755:PALM2AKAP2
gene id: 9755:PALM2AKAP2
uniprot id: A0A455BKG9
uniprot id: A0A455BKT1
uniprot id: A0A455BL66
uniprot id: A0A455BL70
uniprot id: A0A455BNP9
uniprot id: A0A455C0F3
uniprot id: A0A455C0F7
names: Similarity
messages: Belongs to the paralemmin family.

9755:FUNDC1
gene id: 9755:FUNDC1
uniprot id: A0A2Y9F895
uniprot id: A0A455ANZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FUN14 family.
messages: Mitochondrion outer membrane

9755:NDUFV1
gene id: 9755:NDUFV1
uniprot id: A0A2Y9TJJ9
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

9755:PRC1
gene id: 9755:PRC1
uniprot id: A0A2Y9SB41
names: Similarity
messages: Belongs to the MAP65/ASE1 family.

9755:MYO1C
gene id: 9755:MYO1C
uniprot id: A0A455C0J0
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:KIF2A
gene id: 9755:KIF2A
uniprot id: A0A2Y9T8I5
uniprot id: A0A2Y9TD17
uniprot id: A0A2Y9TEX1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9755:SLC25A36
gene id: 9755:SLC25A36
uniprot id: A0A2Y9F598
uniprot id: A0A2Y9F5E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9755:OTC
gene id: 9755:OTC
uniprot id: A0A2Y9FRK9
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
messages: Homotrimer.

9755:NCOR1
gene id: 9755:NCOR1
uniprot id: A0A2Y9T6C7
names: Similarity
messages: Belongs to the N-CoR nuclear receptor corepressors family.

9755:LOC112063752
gene id: 9755:LOC112063752
uniprot id: A0A2Y9S942
names: Similarity
messages: Belongs to the GrpE family.

9755:MMP11
gene id: 9755:MMP11
uniprot id: A0A455AJD6
uniprot id: A0A455AKY3
uniprot id: A0A455AXF9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

9755:PSMG1
gene id: 9755:PSMG1
uniprot id: A0A2Y9SBU7
uniprot id: A0A2Y9SFS2
uniprot id: A0A455BHN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PSMG1 family.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with psmg2.
messages: Cytoplasm
messages: Forms a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer interacts directly with the PSMA5 and PSMA7 proteasome alpha subunits.
messages: Forms a heterodimer with psmg2.

9755:EIF3M
gene id: 9755:EIF3M
uniprot id: A0A2Y9EYF2
uniprot id: A0A2Y9EZY3
uniprot id: A0A2Y9S6P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Belongs to the eIF-3 subunit M family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm

9755:LOC114484418
gene id: 9755:LOC114484418
uniprot id: A0A455AIY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

9755:FAM234A
gene id: 9755:FAM234A
uniprot id: A0A2Y9FVR7
uniprot id: A0A455C5Y4
names: Similarity
messages: Belongs to the FAM234 family.

9755:APLNR
gene id: 9755:APLNR
uniprot id: A0A2Y9FL39
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9755:OPN3
gene id: 9755:OPN3
uniprot id: A0A2Y9TIL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.

9755:LOC114484480
gene id: 9755:LOC114484480
uniprot id: A0A455AJY7
names: Subcellular Location Annotation
messages: Secreted

9755:CCZ1
gene id: 9755:CCZ1
uniprot id: A0A2Y9SB26
uniprot id: A0A455BZK7
uniprot id: A0A455C2J2
names: Similarity
messages: Belongs to the CCZ1 family.

9755:ZSCAN32
gene id: 9755:ZSCAN32
uniprot id: A0A2Y9FD01
names: Subcellular Location Annotation
messages: Nucleus

9755:CUBN
gene id: 9755:CUBN
uniprot id: A0A2Y9FCH3
names: Caution
names: Similarity
messages: Belongs to the DMBT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:POGLUT3
gene id: 9755:POGLUT3
uniprot id: A0A2Y9FEH2
names: Similarity
messages: Belongs to the KDELC family.

9755:LIMS2
gene id: 9755:LIMS2
uniprot id: A0A2Y9S4M8
uniprot id: A0A455C6X5
uniprot id: A0A455C742
uniprot id: A0A455C9H2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Adapter protein in a cytoplasmic complex linking beta-integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors.
messages: Cell membrane
messages: Part of the heterotrimeric IPP complex composed of integrin-linked kinase (ILK), LIMS1 or LIMS2, and PARVA.
messages: focal adhesion

9755:UXS1
gene id: 9755:UXS1
uniprot id: A0A2Y9FQ93
uniprot id: A0A2Y9S178
uniprot id: A0A2Y9S977
uniprot id: A0A455BVH0
uniprot id: A0A455BVH3
uniprot id: A0A455BW53
uniprot id: A0A455BYX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: Golgi stack membrane
messages: Membrane

9755:STK32B
gene id: 9755:STK32B
uniprot id: A0A2Y9SD70
names: Similarity
messages: Belongs to the protein kinase superfamily.

9755:LOC102975167
gene id: 9755:LOC102975167
uniprot id: A0A2Y9SWN6
names: Similarity
messages: Belongs to the TECPR1 family.

9755:ARV1
gene id: 9755:ARV1
uniprot id: A0A2Y9FNU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARV1 family.
messages: Endoplasmic reticulum membrane
messages: Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.
messages: Membrane

9755:CLDN6
gene id: 9755:CLDN6
uniprot id: A0A2Y9EEL0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9755:DESI2
gene id: 9755:DESI2
uniprot id: A0A2Y9TES5
uniprot id: A0A2Y9TGU4
uniprot id: A0A2Y9TJX7
uniprot id: A0A455B8Y2
names: Similarity
messages: Belongs to the DeSI family.

9755:CPA6
gene id: 9755:CPA6
uniprot id: A0A2Y9SZV3
names: Similarity
messages: Belongs to the peptidase M14 family.

9755:SCTR
gene id: 9755:SCTR
uniprot id: A0A2Y9EJX1
names: Subcellular Location Annotation
messages: Membrane

9755:PIAS4
gene id: 9755:PIAS4
uniprot id: A0A2Y9TH01
uniprot id: A0A455CBA6
names: Similarity
messages: Belongs to the PIAS family.

9755:SIKE1
gene id: 9755:SIKE1
uniprot id: A0A2Y9FDR3
uniprot id: A0A455B9X9
names: Similarity
messages: Belongs to the SIKE family.

9755:SLC16A2
gene id: 9755:SLC16A2
uniprot id: A0A2Y9T6Q4
names: Subcellular Location Annotation
messages: Membrane

9755:LOC102977927
gene id: 9755:LOC102977927
uniprot id: A0A2Y9T3U0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.

9755:NDUFS1
gene id: 9755:NDUFS1
uniprot id: A0A2Y9EYW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 75 kDa subunit family.
messages: Mitochondrion inner membrane

9755:RFLNA
gene id: 9755:RFLNA
uniprot id: A0A455AJ10
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Refilin family.
messages: Interacts with FLNA and FLNB.
messages: cytoskeleton

9755:FGF10
gene id: 9755:FGF10
uniprot id: A0A2Y9FSN9
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9755:LOC102986691
gene id: 9755:LOC102986691
uniprot id: A0A2Y9EGG4
uniprot id: A0A455ABM2
uniprot id: A0A455ACT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-2 subfamily.
messages: Nucleus
messages: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR.
messages: nucleolus

9755:DIMT1
gene id: 9755:DIMT1
uniprot id: A0A2Y9FVT8
uniprot id: A0A2Y9TD70
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

9755:SLC52A3
gene id: 9755:SLC52A3
uniprot id: A0A2Y9FIT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

9755:CCDC22
gene id: 9755:CCDC22
uniprot id: A0A2Y9F3B2
names: Similarity
messages: Belongs to the CCDC22 family.

9755:SEC24B
gene id: 9755:SEC24B
uniprot id: A0A2Y9S9I1
uniprot id: A0A2Y9SCM5
uniprot id: A0A2Y9SFM1
uniprot id: A0A2Y9SH64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

9755:FPGS
gene id: 9755:FPGS
uniprot id: A0A2Y9EGI6
uniprot id: A0A2Y9EHU1
names: Cofactor
names: Function
names: Similarity
messages: A monovalent cation.
messages: Belongs to the folylpolyglutamate synthase family.
messages: Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis.

9755:MRPL54
gene id: 9755:MRPL54
uniprot id: A0A2Y9EP21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL54 family.
messages: Mitochondrion

9755:YRDC
gene id: 9755:YRDC
uniprot id: A0A2Y9EH10
names: Similarity
messages: Belongs to the SUA5 family.

9755:RTN4
gene id: 9755:RTN4
uniprot id: A0A2Y9ERX3
uniprot id: A0A2Y9S6Q4
uniprot id: A0A2Y9S6Z7
uniprot id: A0A2Y9SAF6
uniprot id: A0A455BVG2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:DTD2
gene id: 9755:DTD2
uniprot id: A0A2Y9F217
uniprot id: A0A2Y9F2X9
uniprot id: A0A2Y9F3G7
names: Similarity
messages: Belongs to the DTD family.

9755:ANAPC16
gene id: 9755:ANAPC16
uniprot id: A0A2Y9EM97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC16 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: Cytoplasm
messages: Nucleus
messages: kinetochore

9755:NIPAL3
gene id: 9755:NIPAL3
uniprot id: A0A2Y9SQS6
uniprot id: A0A2Y9SS53
uniprot id: A0A2Y9SUG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

9755:PSMB6
gene id: 9755:PSMB6
uniprot id: A0A2Y9EW98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

9755:AURKB
gene id: 9755:AURKB
uniprot id: A0A2Y9FM95
uniprot id: A0A2Y9FMN5
uniprot id: A0A2Y9FNR4
uniprot id: A0A2Y9T019
uniprot id: A0A2Y9T6H8
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.

9755:GTF2H5
gene id: 9755:GTF2H5
uniprot id: A0A2Y9FGY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB5 family.
messages: Component of the 7-subunit TFIIH core complex.
messages: In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.
messages: Nucleus

9755:SELENOP
gene id: 9755:SELENOP
uniprot id: A0A2Y9FBW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenoprotein P family.
messages: Secreted

9755:RPS15A
gene id: 9755:RPS15A
uniprot id: A0A2Y9STZ9
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

9755:HOOK1
gene id: 9755:HOOK1
uniprot id: A0A2Y9ENU2
uniprot id: A0A455B8M6
uniprot id: A0A455BMN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hook family.
messages: cytoskeleton

9755:TYRO3
gene id: 9755:TYRO3
uniprot id: A0A2Y9S4K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Membrane

9755:PAPOLA
gene id: 9755:PAPOLA
uniprot id: A0A2Y9FS47
uniprot id: A0A2Y9FS75
uniprot id: A0A455C872
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Binds 2 magnesium ions. Also active with manganese.
messages: Nucleus
messages: Polymerase that creates the 3'-poly(A) tail of mRNA's.

9755:EPB42
gene id: 9755:EPB42
uniprot id: A0A2Y9FG13
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.

9755:RPS21
gene id: 9755:RPS21
uniprot id: A0A2Y9T057
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS21 family.
messages: Component of the 40S small ribosomal subunit.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum
messages: cytosol

9755:FAM13A
gene id: 9755:FAM13A
uniprot id: A0A2Y9SWC3
uniprot id: A0A2Y9SYS4
uniprot id: A0A2Y9T304
uniprot id: A0A455BEK0
uniprot id: A0A455BF46
uniprot id: A0A455BF75
names: Similarity
messages: Belongs to the FAM13 family.

9755:FGF19
gene id: 9755:FGF19
uniprot id: A0A2Y9FI90
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9755:RPLP0
gene id: 9755:RPLP0
uniprot id: A0A2Y9FT57
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Ribosomal protein P0 is the functional equivalent of E.coli protein L10.

9755:SPOUT1
gene id: 9755:SPOUT1
uniprot id: A0A2Y9EJ34
uniprot id: A0A2Y9EL14
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily.

9755:GATB
gene id: 9755:GATB
uniprot id: A0A2Y9T2U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

9755:ENKUR
gene id: 9755:ENKUR
uniprot id: A0A2Y9T9F3
uniprot id: A0A455BSV5
names: Subcellular Location Annotation
messages: cilium axoneme

9755:UBE3A
gene id: 9755:UBE3A
uniprot id: A0A2Y9F4C9
uniprot id: A0A2Y9TIQ0
uniprot id: A0A2Y9TL43
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9755:HAAO
gene id: 9755:HAAO
uniprot id: A0A2Y9FB90
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 3-HAO family.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

9755:PATL1
gene id: 9755:PATL1
uniprot id: A0A2Y9FE97
uniprot id: A0A455C6B1
uniprot id: A0A455C6J9
names: Similarity
messages: Belongs to the PAT1 family.

9755:STC1
gene id: 9755:STC1
uniprot id: A0A2Y9EEX9
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.

9755:NR1H4
gene id: 9755:NR1H4
uniprot id: A0A2Y9EIE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

9755:CD55
gene id: 9755:CD55
uniprot id: A0A2Y9TH95
uniprot id: A0A2Y9TK82
uniprot id: A0A2Y9TKI8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:TSPO2
gene id: 9755:TSPO2
uniprot id: A0A2Y9FAE4
uniprot id: A0A455AHA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

9755:HSD17B13
gene id: 9755:HSD17B13
uniprot id: A0A2Y9FF82
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9755:ACTBL2
gene id: 9755:ACTBL2
uniprot id: A0A2Y9FUP8
names: Similarity
messages: Belongs to the actin family.

9755:RFTN1
gene id: 9755:RFTN1
uniprot id: A0A2Y9RXC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the raftlin family.
messages: Cell membrane
messages: Membrane

9755:ERH
gene id: 9755:ERH
uniprot id: A0A2Y9F9G4
names: Function
names: Similarity
messages: Belongs to the E(R) family.
messages: May have a role in the cell cycle.

9755:ABCG4
gene id: 9755:ABCG4
uniprot id: A0A2Y9FJH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

9755:NUDT21
gene id: 9755:NUDT21
uniprot id: A0A2Y9EP74
uniprot id: A0A2Y9EPA9
uniprot id: A0A455ACI0
uniprot id: A0A455APM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family. CPSF5 subfamily.
messages: Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.
messages: Cytoplasm
messages: Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.
messages: Nucleus

9755:PSAT1
gene id: 9755:PSAT1
uniprot id: A0A2Y9SWH0
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.

9755:OGN
gene id: 9755:OGN
uniprot id: A0A2Y9EY37
names: Similarity
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.

9755:DCTN1
gene id: 9755:DCTN1
uniprot id: A0A2Y9ETE0
uniprot id: A0A455BUE5
uniprot id: A0A455BV31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin 150 kDa subunit family.
messages: Cytoplasm
messages: cell cortex
messages: cytoskeleton

9755:LOC102993304
gene id: 9755:LOC102993304
uniprot id: A0A455BYM7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

9755:LOC112063648
gene id: 9755:LOC112063648
uniprot id: A0A2Y9S8W1
names: Similarity
messages: Belongs to the peptidase M17 family.

9755:GTF2B
gene id: 9755:GTF2B
uniprot id: A0A2Y9EWI2
names: Similarity
messages: Belongs to the TFIIB family.

9755:LOC112067444
gene id: 9755:LOC112067444
uniprot id: A0A455C836
uniprot id: A0A455CBZ4
names: Similarity
messages: Belongs to the peptidase A1 family.

9755:GPD1L
gene id: 9755:GPD1L
uniprot id: A0A2Y9S0W7
uniprot id: A0A2Y9S8X4
uniprot id: A0A455AE31
uniprot id: A0A455ARW1
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

9755:ERC2
gene id: 9755:ERC2
uniprot id: A0A2Y9SST0
uniprot id: A0A2Y9SUQ9
names: Subcellular Location Annotation
messages: Cytoplasm

9755:LOC102986245
gene id: 9755:LOC102986245
uniprot id: A0A2Y9EQP6
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9755:GALNT1
gene id: 9755:GALNT1
uniprot id: A0A2Y9FCN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9755:OTULIN
gene id: 9755:OTULIN
uniprot id: A0A2Y9EGQ1
uniprot id: A0A2Y9EHD4
uniprot id: A0A455BIP4
uniprot id: A0A455BXT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C65 family. Otulin subfamily.
messages: Cytoplasm

9755:LHX2
gene id: 9755:LHX2
uniprot id: A0A2Y9SU80
names: Subcellular Location Annotation
messages: Nucleus

9755:PHACTR2
gene id: 9755:PHACTR2
uniprot id: A0A2Y9SR52
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

9755:CCN2
gene id: 9755:CCN2
uniprot id: A0A2Y9SIZ2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9755:CLSTN2
gene id: 9755:CLSTN2
uniprot id: A0A455BAU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsyntenin family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Postsynaptic cell membrane

9755:NPTX2
gene id: 9755:NPTX2
uniprot id: A0A2Y9EWP2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:LOC102974667
gene id: 9755:LOC102974667
uniprot id: A0A2Y9S6M0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:SLC5A12
gene id: 9755:SLC5A12
uniprot id: A0A2Y9EUJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

9755:MOS
gene id: 9755:MOS
uniprot id: A0A2Y9EJ90
names: Similarity
messages: Belongs to the protein kinase superfamily.

9755:POMT2
gene id: 9755:POMT2
uniprot id: A0A2Y9EQB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

9755:LARS2
gene id: 9755:LARS2
uniprot id: A0A2Y9SLS1
uniprot id: A0A2Y9SUY4
uniprot id: A0A455AFW0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9755:DONSON
gene id: 9755:DONSON
uniprot id: A0A2Y9SES8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DONSON family.
messages: Nucleus

9755:NECAP1
gene id: 9755:NECAP1
uniprot id: A0A2Y9FB25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

9755:CAPZA2
gene id: 9755:CAPZA2
uniprot id: A0A2Y9F7C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

9755:SEC22B
gene id: 9755:SEC22B
uniprot id: A0A2Y9FIR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Melanosome
messages: Membrane
messages: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

9755:NAA25
gene id: 9755:NAA25
uniprot id: A0A2Y9F3C3
uniprot id: A0A2Y9F3I5
names: Similarity
messages: Belongs to the MDM20/NAA25 family.

9755:NOTCH2
gene id: 9755:NOTCH2
uniprot id: A0A2Y9SGX7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

9755:GPX2
gene id: 9755:GPX2
uniprot id: A0A2Y9FG39
names: Similarity
messages: Belongs to the glutathione peroxidase family.

9755:SCML2
gene id: 9755:SCML2
uniprot id: A0A2Y9ESP7
uniprot id: A0A2Y9ESX4
uniprot id: A0A2Y9EU22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

9755:TMEM126A
gene id: 9755:TMEM126A
uniprot id: A0A2Y9FLL0
uniprot id: A0A455C992
names: Subcellular Location Annotation
messages: Membrane

9755:MCTS1
gene id: 9755:MCTS1
uniprot id: A0A2Y9FG21
uniprot id: A0A2Y9FGB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCTS1 family.
messages: Cytoplasm

9755:AK5
gene id: 9755:AK5
uniprot id: A0A2Y9EYH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylate kinase family.
messages: Cytoplasm

9755:GABRE
gene id: 9755:GABRE
uniprot id: A0A2Y9F153
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9755:ADAMTS5
gene id: 9755:ADAMTS5
uniprot id: A0A2Y9FIN9
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9755:EBF2
gene id: 9755:EBF2
uniprot id: A0A2Y9FNS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

9755:SCN5A
gene id: 9755:SCN5A
uniprot id: A0A2Y9EYQ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

9755:AOPEP
gene id: 9755:AOPEP
uniprot id: A0A2Y9TJ82
names: Similarity
messages: Belongs to the peptidase M1 family.

9755:CCK
gene id: 9755:CCK
uniprot id: A0A2Y9EZM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gastrin/cholecystokinin family.
messages: Secreted

9755:DPY19L1
gene id: 9755:DPY19L1
uniprot id: A0A2Y9T535
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

9755:CLIC5
gene id: 9755:CLIC5
uniprot id: A0A2Y9SK66
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

9755:LOC102982687
gene id: 9755:LOC102982687
uniprot id: A0A455AHX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9755:AOC2
gene id: 9755:AOC2
uniprot id: A0A2Y9EGZ5
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

9755:RRN3
gene id: 9755:RRN3
uniprot id: A0A2Y9ENQ3
uniprot id: A0A2Y9SP36
names: Similarity
messages: Belongs to the RRN3 family.

9755:FAM53A
gene id: 9755:FAM53A
uniprot id: A0A2Y9SC77
names: Similarity
messages: Belongs to the FAM53 family.

9755:SLC18A2
gene id: 9755:SLC18A2
uniprot id: A0A2Y9SLW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Vesicular transporter family.
messages: Membrane
messages: secretory vesicle membrane
messages: synaptic vesicle membrane

9755:TP53
gene id: 9755:TP53
uniprot id: A0A455C1G1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Mitochondrion matrix
messages: Nucleus
messages: PML body
messages: centrosome

9755:SRPX2
gene id: 9755:SRPX2
uniprot id: A0A2Y9EVC6
uniprot id: A0A2Y9T2N2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:ERG28
gene id: 9755:ERG28
uniprot id: A0A2Y9F8X0
uniprot id: A0A2Y9S737
uniprot id: A0A2Y9S9Z8
uniprot id: A0A2Y9SA00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG28 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:PNPLA1
gene id: 9755:PNPLA1
uniprot id: A0A455AHP8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:PTK2
gene id: 9755:PTK2
uniprot id: A0A455C3Y9
uniprot id: A0A455C3Z5
uniprot id: A0A455C3Z9
uniprot id: A0A455C518
uniprot id: A0A455C876
uniprot id: A0A455CBB3
uniprot id: A0A455CBB5
names: Subcellular Location Annotation
messages: Cell membrane
messages: cell cortex
messages: focal adhesion

9755:EIF1AX
gene id: 9755:EIF1AX
uniprot id: A0A2Y9EK59
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Component of the 43S pre-initiation complex (43S PIC), which binds to the mRNA cap-proximal region, scans mRNA 5'-untranslated region, and locates the initiation codon. This protein enhances formation of the cap-proximal complex. Together with EIF1, facilitates scanning, start codon recognition, promotion of the assembly of 48S complex at the initiation codon (43S PIC becomes 48S PIC after the start codon is reached), and dissociation of aberrant complexes. After start codon location, together with EIF5B orients the initiator methionine-tRNA in a conformation that allows 60S ribosomal subunit joining to form the 80S initiation complex. Is released after 80S initiation complex formation, just after GTP hydrolysis by EIF5B, and before release of EIF5B. Its globular part is located in the A site of the 40S ribosomal subunit. Its interaction with EIF5 during scanning contribute to the maintenance of EIF1 within the open 43S PIC. In contrast to yeast orthologs, does not bind EIF1.

9755:ACER1
gene id: 9755:ACER1
uniprot id: A0A2Y9EWM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Membrane

9755:PURG
gene id: 9755:PURG
uniprot id: A0A2Y9T8H8
uniprot id: A0A2Y9TC06
uniprot id: A0A455AKK4
uniprot id: A0A455AZ90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

9755:SGSM2
gene id: 9755:SGSM2
uniprot id: A0A455C0H7
names: Similarity
messages: Belongs to the RUTBC family.

9755:TUBA8
gene id: 9755:TUBA8
uniprot id: A0A2Y9EFH7
uniprot id: A0A455BCB0
uniprot id: A0A455BRW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

9755:KCNK15
gene id: 9755:KCNK15
uniprot id: A0A2Y9FJJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

9755:LOC102975296
gene id: 9755:LOC102975296
uniprot id: A0A2Y9EFA3
uniprot id: A0A2Y9TKK5
names: Similarity
messages: Belongs to the Bcl-2 family.

9755:LOC102974999
gene id: 9755:LOC102974999
uniprot id: A0A455BBN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKA2 family.
messages: spindle

9755:MRPL47
gene id: 9755:MRPL47
uniprot id: A0A2Y9EQB0
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

9755:LOC102976925
gene id: 9755:LOC102976925
uniprot id: A0A2Y9S015
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

9755:TSPAN7
gene id: 9755:TSPAN7
uniprot id: A0A455B2Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9755:CHST14
gene id: 9755:CHST14
uniprot id: A0A2Y9EZU9
uniprot id: A0A455BSE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

9755:LOC102987478
gene id: 9755:LOC102987478
uniprot id: A0A2Y9EPX8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:SIX2
gene id: 9755:SIX2
uniprot id: A0A2Y9SEG8
uniprot id: A0A2Y9SFT3
names: Subcellular Location Annotation
messages: Nucleus

9755:LOC102976979
gene id: 9755:LOC102976979
uniprot id: A0A455C8Y5
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

9755:PKN2
gene id: 9755:PKN2
uniprot id: A0A2Y9EVY0
uniprot id: A0A2Y9EW06
uniprot id: A0A2Y9EX01
uniprot id: A0A2Y9EXW0
uniprot id: A0A455B880
uniprot id: A0A455BM70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cleavage furrow
messages: Midbody
messages: Nucleus

9755:LOC102978220
gene id: 9755:LOC102978220
uniprot id: A0A455C439
uniprot id: A0A455C8A9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin.
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

9755:RPL26
gene id: 9755:RPL26
uniprot id: A0A2Y9FMP5
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

9755:FAM166C
gene id: 9755:FAM166C
uniprot id: A0A2Y9SAV5
names: Similarity
messages: Belongs to the CIMIP2 family.

9755:OTOG
gene id: 9755:OTOG
uniprot id: A0A2Y9S7P2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:TMEM106C
gene id: 9755:TMEM106C
uniprot id: A0A2Y9EK73
names: Similarity
messages: Belongs to the TMEM106 family.

9755:FMN2
gene id: 9755:FMN2
uniprot id: A0A2Y9TDK4
names: Similarity
messages: Belongs to the formin homology family. Cappuccino subfamily.

9755:GJB3
gene id: 9755:GJB3
uniprot id: A0A2Y9ESW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9755:MICOS13
gene id: 9755:MICOS13
uniprot id: A0A2Y9EUQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic13 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

9755:DAPK3
gene id: 9755:DAPK3
uniprot id: A0A2Y9EV55
names: Similarity
messages: Belongs to the protein kinase superfamily.

9755:BMPR2
gene id: 9755:BMPR2
uniprot id: A0A2Y9SPM8
uniprot id: A0A2Y9SWW4
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.

9755:ST3GAL2
gene id: 9755:ST3GAL2
uniprot id: A0A2Y9EH07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9755:PPP2R2D
gene id: 9755:PPP2R2D
uniprot id: A0A2Y9SI59
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

9755:PSEN1
gene id: 9755:PSEN1
uniprot id: A0A2Y9EQM3
uniprot id: A0A2Y9ES75
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Cytoplasmic granule
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: Synapse
messages: The PAL motif is required for normal active site conformation.
messages: axon
messages: neuron projection

9755:CDK16
gene id: 9755:CDK16
uniprot id: A0A2Y9EL03
names: Similarity
messages: Belongs to the protein kinase superfamily.

9755:FAM114A1
gene id: 9755:FAM114A1
uniprot id: A0A2Y9S1D3
uniprot id: A0A2Y9S1D5
names: Similarity
messages: Belongs to the FAM114 family.

9755:RPS6KA2
gene id: 9755:RPS6KA2
uniprot id: A0A2Y9ERU8
uniprot id: A0A2Y9ETC1
uniprot id: A0A455BPA1
uniprot id: A0A455C3Q0
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

9755:IRX5
gene id: 9755:IRX5
uniprot id: A0A2Y9STK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

9755:CDH12
gene id: 9755:CDH12
uniprot id: A0A2Y9ERR8
uniprot id: A0A2Y9ET97
uniprot id: A0A2Y9SMM0
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

9755:ARMCX1
gene id: 9755:ARMCX1
uniprot id: A0A2Y9T2W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eutherian X-chromosome-specific Armcx family.
messages: Membrane

9755:UNC5CL
gene id: 9755:UNC5CL
uniprot id: A0A2Y9FAS8
names: Similarity
messages: Belongs to the unc-5 family.

9755:GLI3
gene id: 9755:GLI3
uniprot id: A0A455BB69
uniprot id: A0A455BDL3
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

9755:FZD6
gene id: 9755:FZD6
uniprot id: A0A2Y9FGT6
uniprot id: A0A2Y9T457
uniprot id: A0A455C554
uniprot id: A0A455C5X3
uniprot id: A0A455CBH7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:KIF21A
gene id: 9755:KIF21A
uniprot id: A0A455BER1
uniprot id: A0A455BH72
uniprot id: A0A455BH77
uniprot id: A0A455BTS5
uniprot id: A0A455BTT0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9755:GSTO1
gene id: 9755:GSTO1
uniprot id: A0A2Y9F1K8
uniprot id: A0A2Y9F237
uniprot id: A0A2Y9F3J2
names: Function
names: Similarity
messages: Belongs to the GST superfamily. Omega family.
messages: Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA).

9755:LEPROTL1
gene id: 9755:LEPROTL1
uniprot id: A0A2Y9TAI8
uniprot id: A0A2Y9TGA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

9755:TRIP10
gene id: 9755:TRIP10
uniprot id: A0A2Y9F629
uniprot id: A0A455CB41
names: Subcellular Location Annotation
messages: cytoskeleton

9755:CHST2
gene id: 9755:CHST2
uniprot id: A0A2Y9TFK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

9755:LOC102992106
gene id: 9755:LOC102992106
uniprot id: A0A2Y9FM51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

9755:ITIH2
gene id: 9755:ITIH2
uniprot id: A0A2Y9FDR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

9755:PTMS
gene id: 9755:PTMS
uniprot id: A0A2Y9T1Y7
names: Similarity
messages: Belongs to the pro/parathymosin family.

9755:RUVBL2
gene id: 9755:RUVBL2
uniprot id: A0A2Y9F0F3
uniprot id: A0A2Y9F1Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Dynein axonemal particle
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

9755:DCTPP1
gene id: 9755:DCTPP1
uniprot id: A0A2Y9ERB2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homotetramer.
messages: Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.
messages: cytosol

9755:NLGN3
gene id: 9755:NLGN3
uniprot id: A0A2Y9F3U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

9755:SPARC
gene id: 9755:SPARC
uniprot id: A0A455BKA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
messages: Belongs to the SPARC family.
messages: Membrane
messages: basement membrane

9755:MAML3
gene id: 9755:MAML3
uniprot id: A0A2Y9SW56
uniprot id: A0A455BUJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

9755:LOC102979127
gene id: 9755:LOC102979127
uniprot id: A0A455C1Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
messages: Secreted

9755:DDX52
gene id: 9755:DDX52
uniprot id: A0A2Y9EXF0
uniprot id: A0A2Y9EXW3
uniprot id: A0A2Y9EYT6
uniprot id: A0A455C011
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

9755:TM2D1
gene id: 9755:TM2D1
uniprot id: A0A2Y9SDK2
uniprot id: A0A455B8Y9
names: Subcellular Location Annotation
messages: Membrane

9755:CASP8
gene id: 9755:CASP8
uniprot id: A0A2Y9F1C7
uniprot id: A0A2Y9F269
names: Similarity
messages: Belongs to the peptidase C14A family.

9755:NPC1
gene id: 9755:NPC1
uniprot id: A0A2Y9FQP0
uniprot id: A0A455AKI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

9755:PPP6R2
gene id: 9755:PPP6R2
uniprot id: A0A455BC85
names: Similarity
messages: Belongs to the SAPS family.

9755:DHX9
gene id: 9755:DHX9
uniprot id: A0A2Y9EZM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DEAH subfamily.
messages: Nucleus

9755:PITX2
gene id: 9755:PITX2
uniprot id: A0A2Y9FAG7
uniprot id: A0A2Y9FCB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

9755:LOC114486168
gene id: 9755:LOC114486168
uniprot id: A0A455BKY1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Secreted

9755:DNMBP
gene id: 9755:DNMBP
uniprot id: A0A455AMH1
uniprot id: A0A455AMH6
uniprot id: A0A455AMP4
uniprot id: A0A455AP73
uniprot id: A0A455API0
uniprot id: A0A455B191
names: Subcellular Location Annotation
messages: Cell junction
messages: Golgi stack
messages: Synapse
messages: cytoskeleton

9755:CSNK1G2
gene id: 9755:CSNK1G2
uniprot id: A0A2Y9TKT7
uniprot id: A0A455C5E1
uniprot id: A0A455C8R9
uniprot id: A0A455CBJ4
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

9755:GPR158
gene id: 9755:GPR158
uniprot id: A0A2Y9T9E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9755:BORA
gene id: 9755:BORA
uniprot id: A0A2Y9EWQ0
names: Similarity
messages: Belongs to the BORA family.

9755:CXXC4
gene id: 9755:CXXC4
uniprot id: A0A2Y9SGT5
names: Subcellular Location Annotation
messages: Cytoplasm

9755:ANTXRL
gene id: 9755:ANTXRL
uniprot id: A0A2Y9FF39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

9755:SCML1
gene id: 9755:SCML1
uniprot id: A0A2Y9ENE3
uniprot id: A0A2Y9ENV2
uniprot id: A0A2Y9ENV7
uniprot id: A0A2Y9EPN6
uniprot id: A0A2Y9EPW8
uniprot id: A0A2Y9S4D5
names: Similarity
messages: Belongs to the SCM family.

9755:EMC3
gene id: 9755:EMC3
uniprot id: A0A2Y9F2B2
uniprot id: A0A2Y9F3G5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC3 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

9755:PRPF31
gene id: 9755:PRPF31
uniprot id: A0A2Y9F2F3
uniprot id: A0A455AE17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP31 family.
messages: Cajal body

9755:MRPS5
gene id: 9755:MRPS5
uniprot id: A0A2Y9FAI1
uniprot id: A0A2Y9T3W0
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

9755:GTPBP10
gene id: 9755:GTPBP10
uniprot id: A0A2Y9FFS3
uniprot id: A0A2Y9FG03
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

9755:PDSS1
gene id: 9755:PDSS1
uniprot id: A0A2Y9T551
uniprot id: A0A455BSR7
uniprot id: A0A455BVF6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

9755:LOC102973898
gene id: 9755:LOC102973898
uniprot id: A0A2Y9FKE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm
messages: May play a role in lipid transport protein in Schwann cells. May bind cholesterol.
messages: Monomer.

9755:UFC1
gene id: 9755:UFC1
uniprot id: A0A2Y9F1S0
names: Function
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UFC1 subfamily.
messages: E1-like enzyme which specifically catalyzes the second step in ufmylation. Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.

9755:APAF1
gene id: 9755:APAF1
uniprot id: A0A2Y9T568
uniprot id: A0A455BBZ3
uniprot id: A0A455BQX3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Monomer. Oligomerizes upon binding of cytochrome c and dATP.
messages: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.

9755:NCSTN
gene id: 9755:NCSTN
uniprot id: A0A2Y9FSD2
uniprot id: A0A2Y9FUB6
uniprot id: A0A2Y9FV81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicastrin family.
messages: Membrane

9755:MMD
gene id: 9755:MMD
uniprot id: A0A2Y9SZ61
uniprot id: A0A2Y9T1P6
uniprot id: A0A2Y9T5Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

9755:CRHR2
gene id: 9755:CRHR2
uniprot id: A0A2Y9FT67
uniprot id: A0A2Y9FV40
uniprot id: A0A455B9S6
uniprot id: A0A455BAA4
uniprot id: A0A455BAK5
uniprot id: A0A455BCQ5
uniprot id: A0A455BPB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Membrane

9755:ADAM22
gene id: 9755:ADAM22
uniprot id: A0A2Y9TBI3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:CGAS
gene id: 9755:CGAS
uniprot id: A0A2Y9F8V6
names: Similarity
messages: Belongs to the mab-21 family.

9755:ZSCAN12
gene id: 9755:ZSCAN12
uniprot id: A0A2Y9FHH7
uniprot id: A0A455AFL4
names: Subcellular Location Annotation
messages: Nucleus

9755:SDR42E2
gene id: 9755:SDR42E2
uniprot id: A0A2Y9EK67
names: Similarity
messages: Belongs to the 3-beta-HSD family.

9755:GABRB1
gene id: 9755:GABRB1
uniprot id: A0A2Y9TFY6
uniprot id: A0A2Y9THJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9755:LOC102977168
gene id: 9755:LOC102977168
uniprot id: A0A2Y9RXL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

9755:EBAG9
gene id: 9755:EBAG9
uniprot id: A0A2Y9T4H0
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.

9755:SAR1B
gene id: 9755:SAR1B
uniprot id: A0A2Y9ER08
names: Similarity
messages: Belongs to the small GTPase superfamily. SAR1 family.

9755:PDCD4
gene id: 9755:PDCD4
uniprot id: A0A2Y9SG50
uniprot id: A0A2Y9SNR3
names: Similarity
messages: Belongs to the PDCD4 family.

9755:ADCY2
gene id: 9755:ADCY2
uniprot id: A0A2Y9SFI4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

9755:PTP4A1
gene id: 9755:PTP4A1
uniprot id: A0A2Y9TGU2
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

9755:LIN52
gene id: 9755:LIN52
uniprot id: A0A2Y9SA52
names: Similarity
messages: Belongs to the lin-52 family.

9755:TMPO
gene id: 9755:TMPO
uniprot id: A0A2Y9T2F8
uniprot id: A0A2Y9T4K9
uniprot id: A0A455BED0
uniprot id: A0A455BQW8
names: Similarity
messages: Belongs to the LEM family.

9755:RPS9
gene id: 9755:RPS9
uniprot id: A0A2Y9F2E8
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

9755:RIPK2
gene id: 9755:RIPK2
uniprot id: A0A2Y9SW09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
messages: Cytoplasm
messages: Found in a signaling complex consisting of at least ARHGEF2, NOD2 and RIPK2.
messages: Serine/threonine/tyrosine-protein kinase that plays an essential role in modulation of innate and adaptive immune responses. Acts as a key effector of NOD1 and NOD2 signaling pathways: upon activation by bacterial peptidoglycans, NOD1 and NOD2 oligomerize and recruit RIPK2 via CARD-CARD domains, leading to the formation of RIPK2 filaments.

9755:PURA
gene id: 9755:PURA
uniprot id: A0A2Y9SEJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

9755:ARHGEF3
gene id: 9755:ARHGEF3
uniprot id: A0A2Y9FUC3
uniprot id: A0A455AEH0
uniprot id: A0A455ASB6
names: Function
names: Subcellular Location Annotation
messages: Acts as guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases.
messages: Cytoplasm

9755:LOC102980255
gene id: 9755:LOC102980255
uniprot id: A0A2Y9S4Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

9755:ADGRV1
gene id: 9755:ADGRV1
uniprot id: A0A2Y9SZ83
names: Subcellular Location Annotation
messages: Membrane

9755:ACTA1
gene id: 9755:ACTA1
uniprot id: A0A2Y9S7L7
names: Similarity
messages: Belongs to the actin family.

9755:FAM133A
gene id: 9755:FAM133A
uniprot id: A0A2Y9TB87
names: Similarity
messages: Belongs to the FAM133 family.

9755:TNFRSF4
gene id: 9755:TNFRSF4
uniprot id: A0A2Y9SYW7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:PRPS1L1
gene id: 9755:PRPS1L1
uniprot id: A0A2Y9TFI0
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

9755:RWDD3
gene id: 9755:RWDD3
uniprot id: A0A2Y9F6M8
uniprot id: A0A2Y9SHG9
uniprot id: A0A455BAB9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9755:KCNQ2
gene id: 9755:KCNQ2
uniprot id: A0A2Y9SZV4
uniprot id: A0A2Y9T1H6
uniprot id: A0A2Y9T3R3
uniprot id: A0A2Y9T7Y1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9755:KCNQ5
gene id: 9755:KCNQ5
uniprot id: A0A455BNJ7
uniprot id: A0A455BP40
uniprot id: A0A455BRQ0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9755:IST1
gene id: 9755:IST1
uniprot id: A0A2Y9SQ85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IST1 family.
messages: Cytoplasmic vesicle
messages: Nucleus envelope

9755:GPX1
gene id: 9755:GPX1
uniprot id: A0A455ATU6
names: Similarity
messages: Belongs to the glutathione peroxidase family.

9755:ST3GAL6
gene id: 9755:ST3GAL6
uniprot id: A0A2Y9SEI1
uniprot id: A0A455BQ24
uniprot id: A0A455C1W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9755:IQSEC2
gene id: 9755:IQSEC2
uniprot id: A0A2Y9F6P3
uniprot id: A0A455AP49
names: Similarity
messages: Belongs to the BRAG family.

9755:GNA13
gene id: 9755:GNA13
uniprot id: A0A2Y9EL95
uniprot id: A0A2Y9T862
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

9755:LOC102993067
gene id: 9755:LOC102993067
uniprot id: A0A2Y9F4L2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9755:UBE2B
gene id: 9755:UBE2B
uniprot id: A0A2Y9EQG3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9755:CPB2
gene id: 9755:CPB2
uniprot id: A0A2Y9SYZ1
names: Similarity
messages: Belongs to the peptidase M14 family.

9755:ZFP69B
gene id: 9755:ZFP69B
uniprot id: A0A455AWJ2
names: Subcellular Location Annotation
messages: Nucleus

9755:JAKMIP2
gene id: 9755:JAKMIP2
uniprot id: A0A2Y9F9S8
uniprot id: A0A2Y9SNQ1
names: Similarity
messages: Belongs to the JAKMIP family.

9755:PTPRK
gene id: 9755:PTPRK
uniprot id: A0A2Y9SHY2
uniprot id: A0A2Y9SII5
uniprot id: A0A2Y9SLF4
uniprot id: A0A455BMQ7
uniprot id: A0A455BNF1
uniprot id: A0A455C2V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Membrane

9755:FOXR1
gene id: 9755:FOXR1
uniprot id: A0A455C898
names: Subcellular Location Annotation
messages: Nucleus

9755:TOR3A
gene id: 9755:TOR3A
uniprot id: A0A2Y9TGT9
uniprot id: A0A2Y9TII0
uniprot id: A0A455B6J3
names: Similarity
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.

9755:SSH1
gene id: 9755:SSH1
uniprot id: A0A455AWA2
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

9755:MBOAT2
gene id: 9755:MBOAT2
uniprot id: A0A2Y9EEX5
uniprot id: A0A2Y9S8C5
uniprot id: A0A2Y9SBK0
names: Subcellular Location Annotation
messages: Membrane

9755:ENPEP
gene id: 9755:ENPEP
uniprot id: A0A2Y9FAE0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Membrane

9755:GRK2
gene id: 9755:GRK2
uniprot id: A0A2Y9TK15
uniprot id: A0A455C7D9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

9755:VAMP3
gene id: 9755:VAMP3
uniprot id: A0A2Y9EPJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

9755:PEBP1
gene id: 9755:PEBP1
uniprot id: A0A2Y9FPY0
names: Similarity
messages: Belongs to the phosphatidylethanolamine-binding protein family.

9755:NUDT7
gene id: 9755:NUDT7
uniprot id: A0A2Y9FAD1
uniprot id: A0A2Y9FC76
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

9755:IRF3
gene id: 9755:IRF3
uniprot id: A0A2Y9EZY0
uniprot id: A0A2Y9F067
uniprot id: A0A2Y9F0I4
names: Subcellular Location Annotation
messages: Nucleus

9755:LOC102986624
gene id: 9755:LOC102986624
uniprot id: A0A2Y9T2T7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:EIPR1
gene id: 9755:EIPR1
uniprot id: A0A2Y9EEU4
uniprot id: A0A2Y9SEL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat EIPR1 family.
messages: trans-Golgi network

9755:PEMT
gene id: 9755:PEMT
uniprot id: A0A455BXY1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
messages: Catalyzes the three sequential steps of the methylation pathway for the biosynthesis of phosphatidylcholine, a critical and essential component for membrane structure. Uses S-adenosylmethionine (S-adenosyl-L-methionine, SAM or AdoMet) as the methyl group donor for the methylation of phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE) to phosphatidylmonomethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine, PMME), PMME to phosphatidyldimethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine, PDME), and PDME to phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine, PC), producing S-adenosyl-L-homocysteine in each step.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

9755:LOC102979402
gene id: 9755:LOC102979402
uniprot id: A0A2Y9S489
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

9755:CLPS
gene id: 9755:CLPS
uniprot id: A0A2Y9EXV3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.
messages: Enterostatin has a biological activity as a satiety signal.
messages: Forms a 1:1 stoichiometric complex with pancreatic lipase.
messages: Secreted

9755:LOC102982068
gene id: 9755:LOC102982068
uniprot id: A0A2Y9TBP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:LOC102997030
gene id: 9755:LOC102997030
uniprot id: A0A2Y9SSZ9
names: Similarity
messages: Belongs to the SelWTH family. Selenoprotein T subfamily.

9755:CPEB4
gene id: 9755:CPEB4
uniprot id: A0A455BWS0
uniprot id: A0A455BXI1
uniprot id: A0A455C9Q0
uniprot id: A0A455C9Q2
names: Similarity
messages: Belongs to the RRM CPEB family.

9755:TXLNB
gene id: 9755:TXLNB
uniprot id: A0A455BQS5
names: Similarity
messages: Belongs to the taxilin family.

9755:TBX21
gene id: 9755:TBX21
uniprot id: A0A2Y9T7D8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9755:SEC63
gene id: 9755:SEC63
uniprot id: A0A2Y9S5Y1
names: Subcellular Location Annotation
messages: Membrane

9755:NUDT4
gene id: 9755:NUDT4
uniprot id: A0A2Y9EKZ2
uniprot id: A0A2Y9T4S7
names: Similarity
messages: Belongs to the Nudix hydrolase family. DIPP subfamily.

9755:BZW2
gene id: 9755:BZW2
uniprot id: A0A2Y9FHF7
uniprot id: A0A455BA87
uniprot id: A0A455BD69
names: Similarity
messages: Belongs to the BZW family.

9755:NDUFB8
gene id: 9755:NDUFB8
uniprot id: A0A2Y9EH19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB8 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9755:DLC1
gene id: 9755:DLC1
uniprot id: A0A2Y9EGX4
uniprot id: A0A455ALU6
uniprot id: A0A455ANL3
uniprot id: A0A455B0A6
names: Subcellular Location Annotation
messages: Cytoplasm

9755:DLX6
gene id: 9755:DLX6
uniprot id: A0A2Y9T7X8
names: Subcellular Location Annotation
messages: Nucleus

9755:EDNRA
gene id: 9755:EDNRA
uniprot id: A0A140GN25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with HDAC7 and KAT5.
messages: Membrane
messages: Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.

9755:PPOX
gene id: 9755:PPOX
uniprot id: A0A2Y9F1R7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily.
messages: Binds 1 FAD per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
messages: Mitochondrion inner membrane

9755:TSPYL1
gene id: 9755:TSPYL1
uniprot id: A0A2Y9EV50
uniprot id: A0A2Y9EX02
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9755:MICAL1
gene id: 9755:MICAL1
uniprot id: A0A2Y9EN02
uniprot id: A0A2Y9RYE9
uniprot id: A0A455BN73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Cytoplasm

9755:RELL1
gene id: 9755:RELL1
uniprot id: A0A2Y9F1K3
uniprot id: A0A455BGE8
names: Similarity
messages: Belongs to the RELT family.

9755:LOC102974554
gene id: 9755:LOC102974554
uniprot id: A0A2Y9TL46
names: Subcellular Location Annotation
messages: Secreted

9755:RUNX1
gene id: 9755:RUNX1
uniprot id: A0A2Y9FPR9
uniprot id: A0A455BHJ9
uniprot id: A0A455BI00
names: Function
names: Subcellular Location Annotation
messages: Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'-TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
messages: Nucleus

9755:OPN5
gene id: 9755:OPN5
uniprot id: A0A2Y9FNI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

9755:JAG2
gene id: 9755:JAG2
uniprot id: A0A2Y9TD76
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

9755:CAPRIN1
gene id: 9755:CAPRIN1
uniprot id: A0A2Y9S6V3
uniprot id: A0A455C7F7
names: Similarity
messages: Belongs to the caprin family.

9755:CALHM6
gene id: 9755:CALHM6
uniprot id: A0A2Y9EVQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

9755:SEC11C
gene id: 9755:SEC11C
uniprot id: A0A2Y9FSF8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Component of the signal peptidase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:LAMC2
gene id: 9755:LAMC2
uniprot id: A0A2Y9THB6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

9755:PRDX6
gene id: 9755:PRDX6
uniprot id: A0A2Y9F3L9
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

9755:PHOX2A
gene id: 9755:PHOX2A
uniprot id: A0A2Y9S6Q8
names: Subcellular Location Annotation
messages: Nucleus

9755:GALM
gene id: 9755:GALM
uniprot id: A0A2Y9F717
uniprot id: A0A455BVJ0
uniprot id: A0A455C8Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldose epimerase family.
messages: Monomer.
messages: Mutarotase that catalyzes the interconversion of beta-D-galactose and alpha-D-galactose during galactose metabolism.

9755:PHC2
gene id: 9755:PHC2
uniprot id: A0A2Y9SQW1
uniprot id: A0A2Y9SWY8
uniprot id: A0A455B121
uniprot id: A0A455B2Y2
uniprot id: A0A455BES2
names: Subcellular Location Annotation
messages: Nucleus

9755:SDHA
gene id: 9755:SDHA
uniprot id: A0A2Y9SM01
uniprot id: A0A2Y9SNS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

9755:LOC102992903
gene id: 9755:LOC102992903
uniprot id: A0A2Y9TFU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:RPS6KB1
gene id: 9755:RPS6KB1
uniprot id: A0A2Y9FA67
uniprot id: A0A2Y9FAD5
uniprot id: A0A2Y9FAP1
uniprot id: A0A2Y9FC81
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

9755:LOC102985876
gene id: 9755:LOC102985876
uniprot id: A0A2Y9SIT5
names: Similarity
messages: Belongs to the CDV3 family.

9755:LIF
gene id: 9755:LIF
uniprot id: A0A2Y9FTC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LIF/OSM family.
messages: LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.
messages: Secreted

9755:HSD17B10
gene id: 9755:HSD17B10
uniprot id: A0A2Y9FJ86
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9755:CLDN5
gene id: 9755:CLDN5
uniprot id: A0A2Y9FBG5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9755:LHFPL7
gene id: 9755:LHFPL7
uniprot id: A0A2Y9FUV1
names: Subcellular Location Annotation
messages: Membrane

9755:LOC112064927
gene id: 9755:LOC112064927
uniprot id: A0A455AGF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Secreted

9755:SEPTIN10
gene id: 9755:SEPTIN10
uniprot id: A0A2Y9FBR7
uniprot id: A0A2Y9S162
uniprot id: A0A2Y9S4N9
uniprot id: A0A2Y9S961
uniprot id: A0A455BVE3
uniprot id: A0A455BVE4
uniprot id: A0A455BW23
uniprot id: A0A455C955
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

9755:LOC102977595
gene id: 9755:LOC102977595
uniprot id: A0A2Y9S813
names: Function
names: Similarity
messages: Belongs to the BLOC1S5 family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO).

9755:LOC102980118
gene id: 9755:LOC102980118
uniprot id: A0A2Y9SQG2
names: Similarity
messages: Belongs to the BTG family.

9755:DCSTAMP
gene id: 9755:DCSTAMP
uniprot id: A0A2Y9T7Y8
names: Subcellular Location Annotation
messages: Membrane

9755:LOC102991698
gene id: 9755:LOC102991698
uniprot id: A0A2Y9F937
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TMEM97/sigma-2 receptor family.
messages: Endoplasmic reticulum membrane
messages: Interacts with NPC1.
messages: Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.
messages: Membrane
messages: Nucleus membrane
messages: Rough endoplasmic reticulum membrane

9755:LOC102975110
gene id: 9755:LOC102975110
uniprot id: A0A2Y9T6P0
names: Subcellular Location Annotation
messages: Membrane

9755:SKAP1
gene id: 9755:SKAP1
uniprot id: A0A2Y9TAM6
names: Similarity
messages: Belongs to the SKAP family.

9755:MMP16
gene id: 9755:MMP16
uniprot id: A0A2Y9SX66
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

9755:MMP20
gene id: 9755:MMP20
uniprot id: A0A2Y9F6H9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

9755:C2H2orf76
gene id: 9755:C2H2orf76
uniprot id: A0A2Y9RWV9
uniprot id: A0A2Y9RWW3
uniprot id: A0A455C990
names: Similarity
messages: Belongs to the UPF0538 family.

9755:LOC102975115
gene id: 9755:LOC102975115
uniprot id: A0A2Y9SY24
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

9755:SOX2
gene id: 9755:SOX2
uniprot id: A0A2Y9FML7
names: Subcellular Location Annotation
messages: Nucleus

9755:LOC102982926
gene id: 9755:LOC102982926
uniprot id: A0A2Y9TBR3
uniprot id: A0A2Y9TFN5
names: Similarity
messages: Belongs to the CARF family.

9755:ADAMTS15
gene id: 9755:ADAMTS15
uniprot id: A0A2Y9TA75
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9755:DLL1
gene id: 9755:DLL1
uniprot id: A0A2Y9SIW1
uniprot id: A0A455BNM9
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

9755:ADK
gene id: 9755:ADK
uniprot id: A0A2Y9TA20
uniprot id: A0A2Y9TC09
uniprot id: A0A2Y9TDY1
uniprot id: A0A2Y9THM4
uniprot id: A0A455ALC4
uniprot id: A0A455ALM7
uniprot id: A0A455AN53
uniprot id: A0A455ANE3
uniprot id: A0A455B040
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Monomer.
messages: Nucleus

9755:ASPHD1
gene id: 9755:ASPHD1
uniprot id: A0A2Y9ESF3
names: Similarity
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.

9755:CSGALNACT2
gene id: 9755:CSGALNACT2
uniprot id: A0A2Y9S5M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

9755:ITGA8
gene id: 9755:ITGA8
uniprot id: A0A2Y9S0K4
uniprot id: A0A2Y9S7J4
uniprot id: A0A455BQN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9755:IZUMO1R
gene id: 9755:IZUMO1R
uniprot id: A0A2Y9T990
names: Similarity
messages: Belongs to the folate receptor family.

9755:ANXA7
gene id: 9755:ANXA7
uniprot id: A0A2Y9TG60
uniprot id: A0A2Y9THR7
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

9755:TBX1
gene id: 9755:TBX1
uniprot id: A0A455AKZ2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9755:RBBP8
gene id: 9755:RBBP8
uniprot id: A0A2Y9F2D3
uniprot id: A0A455AGU1
uniprot id: A0A455AIQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COM1/SAE2/CtIP family.
messages: Nucleus

9755:SLC41A2
gene id: 9755:SLC41A2
uniprot id: A0A2Y9SY81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

9755:CAPN3
gene id: 9755:CAPN3
uniprot id: A0A2Y9ELM2
uniprot id: A0A2Y9ELS1
uniprot id: A0A2Y9EN00
uniprot id: A0A455BQI4
uniprot id: A0A455BQJ6
uniprot id: A0A455BR73
uniprot id: A0A455BTU6
uniprot id: A0A455C5M7
uniprot id: A0A455C5N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C2 family.
messages: Calcium-regulated non-lysosomal thiol-protease.
messages: Cytoplasm
messages: Homodimer.
messages: nucleolus

9755:SLC49A3
gene id: 9755:SLC49A3
uniprot id: A0A455BKH2
names: Subcellular Location Annotation
messages: Membrane

9755:C8H5orf63
gene id: 9755:C8H5orf63
uniprot id: A0A2Y9SL97
uniprot id: A0A455BJS7
names: Similarity
messages: Belongs to the glutaredoxin family.

9755:SERPINA4
gene id: 9755:SERPINA4
uniprot id: A0A2Y9FD62
names: Similarity
messages: Belongs to the serpin family.

9755:SLC8A2
gene id: 9755:SLC8A2
uniprot id: A0A455AEF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

9755:RABEP1
gene id: 9755:RABEP1
uniprot id: A0A2Y9EIV7
uniprot id: A0A2Y9EJK3
uniprot id: A0A455BZP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rabaptin family.
messages: Cytoplasm
messages: Early endosome
messages: Endosome

9755:LOC112064847
gene id: 9755:LOC112064847
uniprot id: A0A2Y9SPV7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9755:ZNF277
gene id: 9755:ZNF277
uniprot id: A0A2Y9T3A9
uniprot id: A0A455B9L5
uniprot id: A0A455BA48
uniprot id: A0A455BAD7
uniprot id: A0A455BCI4
uniprot id: A0A455BCI9
uniprot id: A0A455BP57
names: Similarity
messages: Belongs to the ZNF277 family.

9755:OVCH1
gene id: 9755:OVCH1
uniprot id: A0A2Y9T7J9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:LOC102996065
gene id: 9755:LOC102996065
uniprot id: A0A2Y9EL05
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9755:CMC1
gene id: 9755:CMC1
uniprot id: A0A2Y9S0Z4
uniprot id: A0A455AER6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion

9755:PPIE
gene id: 9755:PPIE
uniprot id: A0A2Y9ST16
uniprot id: A0A2Y9SVE1
uniprot id: A0A455AYJ0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.
messages: Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

9755:TMC1
gene id: 9755:TMC1
uniprot id: A0A2Y9ER90
uniprot id: A0A455BL17
uniprot id: A0A455BPA4
uniprot id: A0A455C106
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:LOC102978885
gene id: 9755:LOC102978885
uniprot id: A0A2Y9TAZ0
names: Similarity
messages: Belongs to the NDK family.

9755:FGD4
gene id: 9755:FGD4
uniprot id: A0A2Y9FAL5
uniprot id: A0A2Y9T8G3
uniprot id: A0A455BDD5
uniprot id: A0A455BE10
uniprot id: A0A455BGE6
names: Subcellular Location Annotation
messages: cytoskeleton

9755:CD40LG
gene id: 9755:CD40LG
uniprot id: A0A2Y9EDS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a ligand for integrins, specifically ITGA5:ITGB1 and ITGAV:ITGB3; both integrins and the CD40 receptor are required for activation of CD40-CD40LG signaling, which have cell-type dependent effects, such as B-cell activation, NF-kappa-B signaling and anti-apoptotic signaling.
messages: Belongs to the tumor necrosis factor family.
messages: Cell surface
messages: Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
messages: Homotrimer.

9755:AGBL2
gene id: 9755:AGBL2
uniprot id: A0A2Y9TDZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

9755:MAGI1
gene id: 9755:MAGI1
uniprot id: A0A2Y9SMK8
uniprot id: A0A2Y9ST07
uniprot id: A0A2Y9SUY9
uniprot id: A0A455AE07
uniprot id: A0A455AEG3
uniprot id: A0A455AFR5
uniprot id: A0A455AGG1
uniprot id: A0A455ART6
names: Subcellular Location Annotation
messages: Membrane

9755:CPPED1
gene id: 9755:CPPED1
uniprot id: A0A2Y9EDM7
names: Function
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. CPPED1 family.
messages: Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. May play an inhibitory role in glucose uptake by adipocytes.

9755:RAG1
gene id: 9755:RAG1
uniprot id: A0A2Y9EQ27
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAG1 family.
messages: Binds 1 divalent metal cation per subunit. Mg(2+) or Mn(2+).
messages: Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities. DNA cleavage occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the phosphodiester bond on the opposite strand in a direct transesterification reaction, thereby creating 4 DNA ends: 2 hairpin coding ends and 2 blunt, 5'-phosphorylated ends.
messages: Homodimer.
messages: Nucleus
messages: The NBD (nonamer binding) DNA-binding domain mediates the specific binding to the nonamer RSS motif by forming a tightly interwoven homodimer that binds and synapses 2 nonamer elements, with each NBD making contact with both DNA molecules. Each RSS is composed of well-conserved heptamer (consensus 5'-CACAGTG-3') and nonamer (consensus 5'-ACAAAAACC-3') sequences separated by a spacer of either 12 bp or 23 bp.

9755:LOC102980092
gene id: 9755:LOC102980092
uniprot id: A0A2Y9TFE4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

9755:SNF8
gene id: 9755:SNF8
uniprot id: A0A2Y9EVU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF8 family.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).

9755:GRHL1
gene id: 9755:GRHL1
uniprot id: A0A455C958
names: Subcellular Location Annotation
messages: Nucleus

9755:MTRF1
gene id: 9755:MTRF1
uniprot id: A0A2Y9SZ13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

9755:NFU1
gene id: 9755:NFU1
uniprot id: A0A2Y9F0Z4
uniprot id: A0A2Y9F2Y7
uniprot id: A0A455BVM7
uniprot id: A0A455BYG4
names: Similarity
messages: Belongs to the NifU family.

9755:ALDH1A1
gene id: 9755:ALDH1A1
uniprot id: A0A2Y9EQ78
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

9755:LOC114484273
gene id: 9755:LOC114484273
uniprot id: A0A455AFN5
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9755:TCAF1
gene id: 9755:TCAF1
uniprot id: A0A2Y9FB39
names: Similarity
messages: Belongs to the TCAF family.

9755:CPOX
gene id: 9755:CPOX
uniprot id: A0A2Y9F6J2
uniprot id: A0A455BPZ3
names: Similarity
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Homodimer.

9755:PDE8B
gene id: 9755:PDE8B
uniprot id: A0A2Y9SF43
uniprot id: A0A2Y9SFX7
uniprot id: A0A2Y9SFZ7
uniprot id: A0A2Y9SIU8
uniprot id: A0A2Y9SIV8
uniprot id: A0A2Y9SLT7
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9755:GABARAPL2
gene id: 9755:GABARAPL2
uniprot id: A0A2Y9F7D3
uniprot id: A0A455AQP0
names: Similarity
messages: Belongs to the ATG8 family.

9755:NEU1
gene id: 9755:NEU1
uniprot id: A0A2Y9EXZ2
uniprot id: A0A455ADM7
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

9755:PCLAF
gene id: 9755:PCLAF
uniprot id: A0A2Y9FDT3
names: Subcellular Location Annotation
messages: Nucleus
messages: perinuclear region

9755:TMEM38B
gene id: 9755:TMEM38B
uniprot id: A0A2Y9SYC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

9755:LOC114487283
gene id: 9755:LOC114487283
uniprot id: A0A455BX92
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.

9755:MFSD4B
gene id: 9755:MFSD4B
uniprot id: A0A2Y9FH76
names: Subcellular Location Annotation
messages: Membrane

9755:LOC102973733
gene id: 9755:LOC102973733
uniprot id: A0A2Y9FQM6
uniprot id: A0A455AIT4
names: Similarity
messages: Belongs to the GST superfamily. Theta family.

9755:LEF1
gene id: 9755:LEF1
uniprot id: A0A2Y9S9Y7
uniprot id: A0A2Y9SD09
uniprot id: A0A2Y9SG14
uniprot id: A0A2Y9SHN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

9755:SLC9A9
gene id: 9755:SLC9A9
uniprot id: A0A2Y9T9I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Endosome membrane
messages: Recycling endosome membrane

9755:MELK
gene id: 9755:MELK
uniprot id: A0A2Y9FNI6
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

9755:RPS6
gene id: 9755:RPS6
uniprot id: A0A2Y9EXF9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

9755:KRT19
gene id: 9755:KRT19
uniprot id: A0A2Y9TAE9
names: Similarity
messages: Belongs to the intermediate filament family.

9755:LOC102982024
gene id: 9755:LOC102982024
uniprot id: A0A2Y9FM36
names: Subcellular Location Annotation
messages: Secreted

9755:ERMN
gene id: 9755:ERMN
uniprot id: A0A2Y9EK43
uniprot id: A0A2Y9SGZ0
names: Function
names: Subunit
messages: Binds actin.
messages: Plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. May play an important role in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the maintenance and plasticity of related structures in the mature CNS.

9755:HMGCLL1
gene id: 9755:HMGCLL1
uniprot id: A0A2Y9SH96
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

9755:IGF2BP3
gene id: 9755:IGF2BP3
uniprot id: A0A2Y9T9C7
uniprot id: A0A2Y9TBV1
uniprot id: A0A2Y9TDZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM IMP/VICKZ family.
messages: P-body
messages: Stress granule

9755:ERO1B
gene id: 9755:ERO1B
uniprot id: A0A2Y9S5N8
uniprot id: A0A455AKD0
uniprot id: A0A455AM59
uniprot id: A0A455AYZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane

9755:TIGD4
gene id: 9755:TIGD4
uniprot id: A0A2Y9FLE4
names: Subcellular Location Annotation
messages: Nucleus

9755:CCL21
gene id: 9755:CCL21
uniprot id: A0A2Y9EF95
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.

9755:LOC102979729
gene id: 9755:LOC102979729
uniprot id: A0A2Y9FFB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

9755:AWAT2
gene id: 9755:AWAT2
uniprot id: A0A2Y9FCR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane

9755:MAP2K6
gene id: 9755:MAP2K6
uniprot id: A0A455C6B6
names: Similarity
messages: Belongs to the protein kinase superfamily.

9755:ETV5
gene id: 9755:ETV5
uniprot id: A0A2Y9F9H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9755:RPL14
gene id: 9755:RPL14
uniprot id: A0A2Y9F6W4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

9755:HOXB9
gene id: 9755:HOXB9
uniprot id: A0A2Y9EVF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

9755:FBLL1
gene id: 9755:FBLL1
uniprot id: A0A2Y9EVV9
names: Similarity
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.

9755:TAF9
gene id: 9755:TAF9
uniprot id: A0A2Y9FT08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus

9755:SCP2
gene id: 9755:SCP2
uniprot id: A0A2Y9SDT5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Cytoplasm
messages: Interacts with PEX5; the interaction is essential for peroxisomal import.
messages: Mitochondrion

9755:SYK
gene id: 9755:SYK
uniprot id: A0A2Y9FIZ2
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.

9755:LOC102995581
gene id: 9755:LOC102995581
uniprot id: A0A2Y9FC01
uniprot id: A0A2Y9FC06
uniprot id: A0A2Y9FC26
uniprot id: A0A2Y9FC32
uniprot id: A0A2Y9FC98
uniprot id: A0A2Y9FCH6
uniprot id: A0A2Y9FCI0
uniprot id: A0A2Y9FE30
uniprot id: A0A2Y9FE34
uniprot id: A0A2Y9SH25
uniprot id: A0A2Y9SKQ5
uniprot id: A0A2Y9SNP6
uniprot id: A0A2Y9SQG7
uniprot id: A0A455BSV4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

9755:KRT17
gene id: 9755:KRT17
uniprot id: A0A2Y9FRF6
names: Similarity
messages: Belongs to the intermediate filament family.

9755:IL26
gene id: 9755:IL26
uniprot id: A0A2Y9EQB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

9755:TMCC3
gene id: 9755:TMCC3
uniprot id: A0A2Y9T0Y0
uniprot id: A0A455BBA2
uniprot id: A0A455BBW4
uniprot id: A0A455BQV3
names: Similarity
messages: Belongs to the TEX28 family.

9755:LOC102973804
gene id: 9755:LOC102973804
uniprot id: A0A2Y9S7W6
names: Similarity
messages: Belongs to the GAGE family.

9755:ANKRD13D
gene id: 9755:ANKRD13D
uniprot id: A0A2Y9EV11
uniprot id: A0A455C7I6
uniprot id: A0A455C7P3
uniprot id: A0A455C7P9
uniprot id: A0A455C886
uniprot id: A0A455C9R1
uniprot id: A0A455CC10
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

9755:KCNJ3
gene id: 9755:KCNJ3
uniprot id: A0A2Y9FVH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
messages: Membrane
messages: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

9755:IMPG1
gene id: 9755:IMPG1
uniprot id: A0A455BRS2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: interphotoreceptor matrix

9755:SUPT20H
gene id: 9755:SUPT20H
uniprot id: A0A2Y9FR26
uniprot id: A0A2Y9SUD6
uniprot id: A0A2Y9SUE1
uniprot id: A0A2Y9T102
uniprot id: A0A455BXG1
uniprot id: A0A455BYA6
uniprot id: A0A455BYB2
uniprot id: A0A455C142
uniprot id: A0A455C148
uniprot id: A0A455C9X8
uniprot id: A0A455C9X9
names: Similarity
messages: Belongs to the SPT20 family.

9755:MTIF3
gene id: 9755:MTIF3
uniprot id: A0A2Y9EZH9
names: Similarity
messages: Belongs to the IF-3 family.

9755:OSBP
gene id: 9755:OSBP
uniprot id: A0A455C6M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sesquipedalian family.
messages: Early endosome
messages: Forms homodimers and heterodimers with PHETA. Interacts with OCRL and INPP5B.
messages: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
messages: Recycling endosome
messages: clathrin-coated vesicle
messages: trans-Golgi network

9755:EIF2AK1
gene id: 9755:EIF2AK1
uniprot id: A0A455CA07
names: Similarity
messages: Belongs to the protein kinase superfamily.

9755:MED13L
gene id: 9755:MED13L
uniprot id: A0A455AJQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

9755:CYYR1
gene id: 9755:CYYR1
uniprot id: A0A2Y9SIN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYYR1 family.
messages: Membrane

9755:ATP8A1
gene id: 9755:ATP8A1
uniprot id: A0A455BG76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

9755:LOC112064220
gene id: 9755:LOC112064220
uniprot id: A0A2Y9SIE4
names: Subcellular Location Annotation
messages: Cytoplasm

9755:SYNE1
gene id: 9755:SYNE1
uniprot id: A0A2Y9SPM9
uniprot id: A0A455BNU0
uniprot id: A0A455BPE9
uniprot id: A0A455BS14
names: Similarity
messages: Belongs to the nesprin family.

9755:ATP6V1D
gene id: 9755:ATP6V1D
uniprot id: A0A2Y9THP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase D subunit family.
messages: cilium
messages: clathrin-coated vesicle membrane

9755:NNMT
gene id: 9755:NNMT
uniprot id: A0A2Y9ER32
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.

9755:NADK2
gene id: 9755:NADK2
uniprot id: A0A2Y9F0F0
uniprot id: A0A2Y9SQZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAD kinase family.
messages: Homodimer.
messages: Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor.
messages: Mitochondrion

9755:CWF19L2
gene id: 9755:CWF19L2
uniprot id: A0A2Y9RXR0
uniprot id: A0A455C5S6
uniprot id: A0A455C915
names: Similarity
messages: Belongs to the CWF19 family.

9755:LOC102976226
gene id: 9755:LOC102976226
uniprot id: A0A2Y9SFN9
uniprot id: A0A455BU64
uniprot id: A0A455BXM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

9755:UBE2F
gene id: 9755:UBE2F
uniprot id: A0A2Y9SNM3
uniprot id: A0A2Y9SPL9
uniprot id: A0A2Y9SWV4
uniprot id: A0A455AQ68
uniprot id: A0A455AQG2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9755:OSBPL1A
gene id: 9755:OSBPL1A
uniprot id: A0A2Y9SHE5
uniprot id: A0A2Y9SM48
names: Similarity
messages: Belongs to the OSBP family.

9755:PIK3CD
gene id: 9755:PIK3CD
uniprot id: A0A2Y9SS64
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

9755:TAF15
gene id: 9755:TAF15
uniprot id: A0A2Y9EMX8
uniprot id: A0A455C1X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TET family.
messages: Nucleus

9755:LOC102977598
gene id: 9755:LOC102977598
uniprot id: A0A2Y9T059
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:SEPTIN9
gene id: 9755:SEPTIN9
uniprot id: A0A455C0W6
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

9755:ZDHHC12
gene id: 9755:ZDHHC12
uniprot id: A0A455BWZ2
uniprot id: A0A455BWZ3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9755:EPHA7
gene id: 9755:EPHA7
uniprot id: A0A2Y9SCQ9
uniprot id: A0A2Y9SH95
names: Subcellular Location Annotation
messages: Membrane

9755:SGTA
gene id: 9755:SGTA
uniprot id: A0A2Y9FDU1
names: Similarity
messages: Belongs to the SGT family.

9755:KCNG4
gene id: 9755:KCNG4
uniprot id: A0A2Y9SXR6
names: Subcellular Location Annotation
messages: Membrane

9755:SIGMAR1
gene id: 9755:SIGMAR1
uniprot id: A0A2Y9EFA0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ERG2 family.
messages: Cell junction
messages: Cytoplasmic vesicle
messages: Endoplasmic reticulum membrane
messages: Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Regulates calcium efflux at the endoplasmic reticulum.
messages: Homotrimer.
messages: Lipid droplet
messages: Membrane
messages: Nucleus envelope
messages: Nucleus inner membrane
messages: Nucleus outer membrane
messages: Postsynaptic density membrane
messages: The C-terminal helices form a flat, hydrophobic surface that is probably tightly associated with the cytosolic surface of the endoplasmic reticulum membrane.
messages: Vesicle
messages: growth cone

9755:ABCG5
gene id: 9755:ABCG5
uniprot id: A0A2Y9SBP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

9755:PTX3
gene id: 9755:PTX3
uniprot id: A0A2Y9SUE5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:KCNMA1
gene id: 9755:KCNMA1
uniprot id: A0A2Y9TG69
uniprot id: A0A2Y9THS5
uniprot id: A0A455AMK5
uniprot id: A0A455AML1
uniprot id: A0A455AMP2
uniprot id: A0A455AMS6
uniprot id: A0A455AMT2
uniprot id: A0A455AZG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa1.1/KCNMA1 sub-subfamily.
messages: Membrane

9755:SCN1B
gene id: 9755:SCN1B
uniprot id: A0A455ACL2
uniprot id: A0A455AF03
uniprot id: A0A455AQ41
names: Subcellular Location Annotation
messages: Membrane

9755:LOC102983817
gene id: 9755:LOC102983817
uniprot id: A0A2Y9SVA7
uniprot id: A0A2Y9SXQ8
names: Similarity
messages: Belongs to the GPSM family.

9755:BCL9
gene id: 9755:BCL9
uniprot id: A0A2Y9FUH6
uniprot id: A0A2Y9SH13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCL9 family.
messages: Nucleus

9755:MZT1
gene id: 9755:MZT1
uniprot id: A0A2Y9EYN6
names: Function
names: Similarity
messages: Belongs to the MOZART1 family.
messages: Required for gamma-tubulin complex recruitment to the centrosome.

9755:NASP
gene id: 9755:NASP
uniprot id: A0A2Y9ETL0
uniprot id: A0A455B979
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NASP family.
messages: Nucleus

9755:ADGRL4
gene id: 9755:ADGRL4
uniprot id: A0A2Y9EJA9
uniprot id: A0A2Y9EKR0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:VXN
gene id: 9755:VXN
uniprot id: A0A2Y9FEG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vexin family.
messages: Cell membrane
messages: Membrane
messages: Nucleus

9755:PIGC
gene id: 9755:PIGC
uniprot id: A0A2Y9ERD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGC family.
messages: Membrane

9755:IYD
gene id: 9755:IYD
uniprot id: A0A2Y9ELN2
names: Subcellular Location Annotation
messages: Cell membrane

9755:NUDT12
gene id: 9755:NUDT12
uniprot id: A0A2Y9EQA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Cytoplasmic granule
messages: Peroxisome

9755:VCAM1
gene id: 9755:VCAM1
uniprot id: A0A2Y9FHT7
names: Subcellular Location Annotation
messages: Cell membrane

9755:ARRDC4
gene id: 9755:ARRDC4
uniprot id: A0A2Y9RZM8
uniprot id: A0A455BPZ1
names: Similarity
messages: Belongs to the arrestin family.

9755:MFSD8
gene id: 9755:MFSD8
uniprot id: A0A2Y9FF14
uniprot id: A0A455BGJ1
uniprot id: A0A455BGZ4
uniprot id: A0A455BH54
uniprot id: A0A455BW81
names: Subcellular Location Annotation
messages: Membrane

9755:PSMC3IP
gene id: 9755:PSMC3IP
uniprot id: A0A2Y9EGD9
uniprot id: A0A2Y9EH16
uniprot id: A0A2Y9EHR2
uniprot id: A0A2Y9EIF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HOP2 family.
messages: Nucleus

9755:PDE4B
gene id: 9755:PDE4B
uniprot id: A0A2Y9SDI8
uniprot id: A0A455BAW1
uniprot id: A0A455BMI3
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9755:BICD2
gene id: 9755:BICD2
uniprot id: A0A2Y9FHT0
uniprot id: A0A2Y9FJL0
names: Similarity
messages: Belongs to the BicD family.

9755:RAPGEF2
gene id: 9755:RAPGEF2
uniprot id: A0A2Y9SUV7
uniprot id: A0A2Y9SYR0
uniprot id: A0A2Y9T0T5
uniprot id: A0A2Y9T0U0
uniprot id: A0A455BEG2
uniprot id: A0A455BF12
uniprot id: A0A455BF17
uniprot id: A0A455BHI3
names: Similarity
messages: Belongs to the RAPGEF2 family.

9755:RAP2A
gene id: 9755:RAP2A
uniprot id: A0A2Y9EGG0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Palmitoylated.
messages: Recycling endosome membrane
messages: Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form.

9755:SLC35F4
gene id: 9755:SLC35F4
uniprot id: A0A2Y9S6E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

9755:GIMAP8
gene id: 9755:GIMAP8
uniprot id: A0A2Y9T3G2
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

9755:TMEM255A
gene id: 9755:TMEM255A
uniprot id: A0A2Y9F6M9
uniprot id: A0A2Y9F762
uniprot id: A0A455ANB7
uniprot id: A0A455AQ01
uniprot id: A0A455B258
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM255 family.
messages: Membrane

9755:GPR55
gene id: 9755:GPR55
uniprot id: A0A2Y9FNB3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9755:LOC112065788
gene id: 9755:LOC112065788
uniprot id: A0A2Y9T3K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC16 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: Cytoplasm
messages: Nucleus
messages: kinetochore

9755:DNAH3
gene id: 9755:DNAH3
uniprot id: A0A455BZ21
uniprot id: A0A455BZ22
uniprot id: A0A455BZ33
uniprot id: A0A455BZ37
uniprot id: A0A455BZ43
uniprot id: A0A455C030
uniprot id: A0A455C042
uniprot id: A0A455C048
uniprot id: A0A455C306
uniprot id: A0A455C313
uniprot id: A0A455C319
uniprot id: A0A455C324
uniprot id: A0A455CA96
uniprot id: A0A455CA98
names: Similarity
messages: Belongs to the dynein heavy chain family.

9755:SH3GL2
gene id: 9755:SH3GL2
uniprot id: A0A2Y9SWR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Membrane

9755:DPYSL3
gene id: 9755:DPYSL3
uniprot id: A0A2Y9SC41
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

9755:DUSP8
gene id: 9755:DUSP8
uniprot id: A0A455AF05
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

9755:SLC25A16
gene id: 9755:SLC25A16
uniprot id: A0A2Y9TC60
uniprot id: A0A2Y9TE22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9755:TTC27
gene id: 9755:TTC27
uniprot id: A0A2Y9S7G7
uniprot id: A0A2Y9SB76
uniprot id: A0A2Y9SFJ1
uniprot id: A0A455BTZ2
names: Similarity
messages: Belongs to the TTC27 family.

9755:TSPYL5
gene id: 9755:TSPYL5
uniprot id: A0A2Y9FGZ7
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9755:EPHA4
gene id: 9755:EPHA4
uniprot id: A0A2Y9EGC9
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome
messages: Membrane

9755:SEMA3D
gene id: 9755:SEMA3D
uniprot id: A0A2Y9TF79
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:VPS18
gene id: 9755:VPS18
uniprot id: A0A455BQL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS18 family.
messages: Membrane

9755:LOC102974991
gene id: 9755:LOC102974991
uniprot id: A0A2Y9T2E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

9755:BID
gene id: 9755:BID
uniprot id: A0A455BCB8
uniprot id: A0A455BCZ9
uniprot id: A0A455BD19
uniprot id: A0A455BFC5
uniprot id: A0A455BRX2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane
messages: Mitochondrion outer membrane

9755:GRPEL1
gene id: 9755:GRPEL1
uniprot id: A0A2Y9SG49
uniprot id: A0A455BGQ9
uniprot id: A0A455BH58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

9755:SMG8
gene id: 9755:SMG8
uniprot id: A0A2Y9ENN5
names: Function
names: Similarity
messages: Belongs to the SMG8 family.
messages: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.

9755:LOC102993821
gene id: 9755:LOC102993821
uniprot id: A0A2Y9SLN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Secreted

9755:TNFSF11
gene id: 9755:TNFSF11
uniprot id: A0A2Y9F8Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane
messages: Secreted

9755:HOXB8
gene id: 9755:HOXB8
uniprot id: A0A2Y9EWQ6
names: Subcellular Location Annotation
messages: Nucleus

9755:TAF7
gene id: 9755:TAF7
uniprot id: A0A2Y9SUF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

9755:UBL4A
gene id: 9755:UBL4A
uniprot id: A0A2Y9S8E4
names: Subcellular Location Annotation
messages: cytosol

9755:AARS2
gene id: 9755:AARS2
uniprot id: A0A2Y9ES45
uniprot id: A0A455AG05
uniprot id: A0A455AGG2
uniprot id: A0A455AHT5
uniprot id: A0A455AI86
names: Caution
names: Cofactor
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: ISGylated.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with ANKRD16; the interaction is direct.

9755:SLC41A1
gene id: 9755:SLC41A1
uniprot id: A0A2Y9F4M5
uniprot id: A0A455B6A5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

9755:DUSP13B
gene id: 9755:DUSP13B
uniprot id: A0A2Y9EGH3
uniprot id: A0A455AL38
uniprot id: A0A455ALE1
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

9755:SHROOM4
gene id: 9755:SHROOM4
uniprot id: A0A2Y9S8T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

9755:YJU2
gene id: 9755:YJU2
uniprot id: A0A2Y9EV61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CWC16 family. YJU2 subfamily.
messages: Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.
messages: Nucleus
messages: Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex.

9755:LOC102995670
gene id: 9755:LOC102995670
uniprot id: A0A455ACY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

9755:TBCC
gene id: 9755:TBCC
uniprot id: A0A2Y9FFH1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCC family.
messages: Cytoplasm
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.

9755:LOC114483930
gene id: 9755:LOC114483930
uniprot id: A0A455C0A8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 27 family.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

9755:LOC102996154
gene id: 9755:LOC102996154
uniprot id: A0A2Y9TB01
uniprot id: A0A455C1B1
uniprot id: A0A455C4B2
names: Similarity
messages: Belongs to the COG1 family.

9755:ASIC3
gene id: 9755:ASIC3
uniprot id: A0A2Y9T8K1
uniprot id: A0A455B8H4
uniprot id: A0A455B8Y5
uniprot id: A0A455B9B4
uniprot id: A0A455BBC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
messages: Membrane

9755:CPLX4
gene id: 9755:CPLX4
uniprot id: A0A2Y9FSI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

9755:EGF
gene id: 9755:EGF
uniprot id: A0A2Y9END4
uniprot id: A0A2Y9ENU1
uniprot id: A0A2Y9EPM1
uniprot id: A0A2Y9EPV8
names: Caution
names: Function
names: Subunit
messages: EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.
messages: Interacts with EGFR and promotes EGFR dimerization.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:PAX2
gene id: 9755:PAX2
uniprot id: A0A2Y9EFG2
uniprot id: A0A2Y9EG56
uniprot id: A0A2Y9EGR4
uniprot id: A0A2Y9EHC3
names: Subcellular Location Annotation
messages: Nucleus

9755:ORC1
gene id: 9755:ORC1
uniprot id: A0A2Y9FRQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC1 family.
messages: Component of ORC, a complex composed of at least 6 subunits: ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. ORC is regulated in a cell-cycle dependent manner. It is sequentially assembled at the exit from anaphase of mitosis and disassembled as cells enter S phase. Interacts with CDC6 and KAT7/HBO1. Interacts with LRWD1 predominantly during the G1 phase and with less affinity during mitosis, when phosphorylated.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Nucleus

9755:SLC15A4
gene id: 9755:SLC15A4
uniprot id: A0A455AKK5
names: Similarity
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.

9755:TRPM8
gene id: 9755:TRPM8
uniprot id: A0A2Y9SXC2
names: Subcellular Location Annotation
messages: Membrane

9755:PDE3B
gene id: 9755:PDE3B
uniprot id: A0A455C877
uniprot id: A0A455C9Q4
uniprot id: A0A455CC07
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9755:ZNF330
gene id: 9755:ZNF330
uniprot id: A0A2Y9ESI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOA36 family.
messages: centromere
messages: nucleolus

9755:CDH22
gene id: 9755:CDH22
uniprot id: A0A2Y9T084
uniprot id: A0A2Y9T403
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

9755:HSF1
gene id: 9755:HSF1
uniprot id: A0A2Y9EMZ4
uniprot id: A0A2Y9S3W8
uniprot id: A0A2Y9S421
uniprot id: A0A2Y9S7H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

9755:GALNT14
gene id: 9755:GALNT14
uniprot id: A0A455BTU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9755:LPCAT4
gene id: 9755:LPCAT4
uniprot id: A0A2Y9FPB3
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

9755:THADA
gene id: 9755:THADA
uniprot id: A0A2Y9FR97
uniprot id: A0A2Y9FT55
uniprot id: A0A2Y9FU01
uniprot id: A0A455BU76
uniprot id: A0A455C8P5
names: Function
names: Similarity
messages: Belongs to the THADA family.
messages: Together with methyltransferase FTSJ1, methylates the 2'-O-ribose of nucleotides at position 32 of the anticodon loop of substrate tRNAs.

9755:GPR37L1
gene id: 9755:GPR37L1
uniprot id: A0A2Y9TE02
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9755:GTF2H3
gene id: 9755:GTF2H3
uniprot id: A0A455AI27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB4 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
messages: Nucleus
messages: Part of a TFIID-containing RNA polymerase II pre-initiation complex that is composed of TBP and at least GTF2A1, GTF2A2, GTF2E1, GTF2E2, GTF2F1, GTF2H2, GTF2H3, GTF2H4, GTF2H5, GTF2B, TCEA1, ERCC2, ERCC3, TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. Component of the 7-subunit TFIIH core complex composed of XPB/ERCC3, XPD/ERCC2, GTF2H1, GTF2H2, GTF2H3, GTF2H4 and GTF2H5, which is active in NER. The core complex associates with the 3-subunit CDK-activating kinase (CAK) module composed of CCNH/cyclin H, CDK7 and MNAT1 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription. Interacts with RARA; the interaction requires prior phosphorylation of RARA on 'Ser-369' which then enhances interaction of RARA with CDK7.

9755:SH2D1A
gene id: 9755:SH2D1A
uniprot id: A0A2Y9F755
uniprot id: A0A2Y9T764
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2.

9755:LOC102991826
gene id: 9755:LOC102991826
uniprot id: A0A2Y9SN16
names: Similarity
messages: Belongs to the potassium channel KCNE family.

9755:DHCR7
gene id: 9755:DHCR7
uniprot id: A0A2Y9F484
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

9755:YARS2
gene id: 9755:YARS2
uniprot id: A0A2Y9FXZ7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9755:LIX1
gene id: 9755:LIX1
uniprot id: A0A2Y9FCH1
names: Similarity
messages: Belongs to the LIX1 family.

9755:LOC102982657
gene id: 9755:LOC102982657
uniprot id: A0A2Y9S6F2
names: Similarity
messages: Belongs to the cytochrome P450 family.

9755:PRODH
gene id: 9755:PRODH
uniprot id: A0A2Y9SIX3
names: Function
names: Similarity
messages: Belongs to the proline oxidase family.
messages: Converts proline to delta-1-pyrroline-5-carboxylate.

9755:RRM1
gene id: 9755:RRM1
uniprot id: A0A2Y9F7W8
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

9755:MOXD1
gene id: 9755:MOXD1
uniprot id: A0A2Y9SIP6
uniprot id: A0A2Y9SLK9
names: Similarity
messages: Belongs to the copper type II ascorbate-dependent monooxygenase family.

9755:MPP3
gene id: 9755:MPP3
uniprot id: A0A2Y9T936
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane

9755:TMEM41A
gene id: 9755:TMEM41A
uniprot id: A0A2Y9FC59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM41 family.
messages: Membrane

9755:CARMIL1
gene id: 9755:CARMIL1
uniprot id: A0A455AI66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CARMIL family.
messages: Cytoplasm

9755:CWF19L1
gene id: 9755:CWF19L1
uniprot id: A0A2Y9F990
uniprot id: A0A2Y9FB16
uniprot id: A0A455AL97
names: Similarity
messages: Belongs to the CWF19 family.

9755:EXOSC9
gene id: 9755:EXOSC9
uniprot id: A0A2Y9FDL4
uniprot id: A0A455BGW0
names: Subcellular Location Annotation
messages: Cytoplasm

9755:CMKLR1
gene id: 9755:CMKLR1
uniprot id: A0A2Y9SHM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

9755:NDRG4
gene id: 9755:NDRG4
uniprot id: A0A2Y9F0W5
uniprot id: A0A2Y9F146
uniprot id: A0A2Y9F2P4
uniprot id: A0A455AC56
uniprot id: A0A455AEJ2
names: Similarity
messages: Belongs to the NDRG family.

9755:MTNR1B
gene id: 9755:MTNR1B
uniprot id: A0A2Y9ES79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9755:PTGES3L
gene id: 9755:PTGES3L
uniprot id: A0A2Y9EGZ0
uniprot id: A0A455C0L0
uniprot id: A0A455C0M1
uniprot id: A0A455C4S7
uniprot id: A0A455CAL4
names: Similarity
messages: Belongs to the p23/wos2 family.

9755:DEUP1
gene id: 9755:DEUP1
uniprot id: A0A455C7Y3
names: Similarity
messages: Belongs to the CEP63 family.

9755:CRMP1
gene id: 9755:CRMP1
uniprot id: A0A2Y9S932
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

9755:NEUROD2
gene id: 9755:NEUROD2
uniprot id: A0A2Y9T797
names: Subcellular Location Annotation
messages: Nucleus

9755:CDK5
gene id: 9755:CDK5
uniprot id: A0A2Y9FM68
names: Similarity
messages: Belongs to the protein kinase superfamily.

9755:SLC7A3
gene id: 9755:SLC7A3
uniprot id: A0A2Y9F3R8
uniprot id: A0A2Y9F3V6
uniprot id: A0A2Y9F4N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

9755:FLNB
gene id: 9755:FLNB
uniprot id: A0A455AF07
names: Similarity
messages: Belongs to the filamin family.

9755:SCAMP1
gene id: 9755:SCAMP1
uniprot id: A0A2Y9FSS0
uniprot id: A0A2Y9FST8
uniprot id: A0A455BJ70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

9755:TAF1A
gene id: 9755:TAF1A
uniprot id: A0A2Y9FNN1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the transcription factor SL1/TIF-IB complex, composed of TBP and at least TAF1A, TAF1B, TAF1C and TAF1D. In the complex interacts directly with TBP, TAF1A and TAF1B. Interaction of the SL1/TIF-IB subunits with TBP excludes interaction of TBP with the transcription factor IID (TFIID) subunits.
messages: Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits.
messages: Nucleus

9755:ADAM33
gene id: 9755:ADAM33
uniprot id: A0A2Y9FAP8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:EZR
gene id: 9755:EZR
uniprot id: A0A2Y9SPN5
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton
messages: microvillus

9755:ORC3
gene id: 9755:ORC3
uniprot id: A0A2Y9EK75
uniprot id: A0A2Y9EKS5
uniprot id: A0A2Y9ELG3
uniprot id: A0A2Y9ELL6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC3 family.
messages: Component of ORC, a complex composed of at least 6 subunits: ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. ORC is regulated in a cell-cycle dependent manner. It is sequentially assembled at the exit from anaphase of mitosis and disassembled as cells enter S phase.
messages: Nucleus

9755:MON1A
gene id: 9755:MON1A
uniprot id: A0A2Y9F3T6
names: Function
names: Similarity
messages: Belongs to the MON1/SAND family.
messages: Plays an important role in membrane trafficking through the secretory apparatus.

9755:KMO
gene id: 9755:KMO
uniprot id: A0A2Y9FCC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.
messages: Mitochondrion outer membrane

9755:LOC102973521
gene id: 9755:LOC102973521
uniprot id: A0A2Y9FIY6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:DYNLRB2
gene id: 9755:DYNLRB2
uniprot id: A0A2Y9FCC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
messages: Belongs to the GAMAD family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs); the composition seems to vary in respect to the IC, LIC and LC composition. The heavy chain homodimer serves as a scaffold for the probable homodimeric assembly of the respective non-catalytic subunits. The ICs and LICs bind directly to the HC dimer and the LCs assemble on the IC dimer.
messages: cytoskeleton

9755:IMPACT
gene id: 9755:IMPACT
uniprot id: A0A2Y9F690
uniprot id: A0A2Y9F6D9
uniprot id: A0A2Y9F721
uniprot id: A0A455AHG4
uniprot id: A0A455AHY2
uniprot id: A0A455AJD5
uniprot id: A0A455AVS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IMPACT family.
messages: Cytoplasm

9755:HS3ST3A1
gene id: 9755:HS3ST3A1
uniprot id: A0A2Y9SY88
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9755:ACVR2B
gene id: 9755:ACVR2B
uniprot id: A0A2Y9TAV5
uniprot id: A0A455AEC0
uniprot id: A0A455AS60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

9755:LOC112065819
gene id: 9755:LOC112065819
uniprot id: A0A2Y9SZF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vasculin family.
messages: Nucleus

9755:DBNDD2
gene id: 9755:DBNDD2
uniprot id: A0A2Y9F677
names: Similarity
messages: Belongs to the dysbindin family.

9755:LOC102979190
gene id: 9755:LOC102979190
uniprot id: A0A2Y9SAE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:RBPMS2
gene id: 9755:RBPMS2
uniprot id: A0A2Y9T320
uniprot id: A0A455BRL9
names: Subcellular Location Annotation
messages: Cytoplasm

9755:KIF7
gene id: 9755:KIF7
uniprot id: A0A2Y9ENR1
uniprot id: A0A455BRM3
uniprot id: A0A455BRN2
uniprot id: A0A455BRN7
uniprot id: A0A455BSC7
uniprot id: A0A455BV09
uniprot id: A0A455C6T1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9755:LOC102992148
gene id: 9755:LOC102992148
uniprot id: A0A2Y9SIE1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.
messages: Nucleus

9755:SHMT1
gene id: 9755:SHMT1
uniprot id: A0A2Y9T1R1
uniprot id: A0A455C783
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

9755:LOC102974623
gene id: 9755:LOC102974623
uniprot id: A0A2Y9SX53
uniprot id: A0A2Y9SZP2
uniprot id: A0A2Y9T1P9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9755:CAP1
gene id: 9755:CAP1
uniprot id: A0A455BIR9
names: Similarity
messages: Belongs to the CAP family.

9755:ZC3H14
gene id: 9755:ZC3H14
uniprot id: A0A2Y9T703
uniprot id: A0A2Y9T708
uniprot id: A0A2Y9TAF4
uniprot id: A0A2Y9TAF8
uniprot id: A0A2Y9TD30
uniprot id: A0A2Y9TD35
uniprot id: A0A2Y9TF08
uniprot id: A0A2Y9TF11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZC3H14 family.
messages: Involved in poly(A) tail length control in neuronal cells. Binds the polyadenosine RNA oligonucleotides.
messages: Nucleus speckle

9755:LIPC
gene id: 9755:LIPC
uniprot id: A0A2Y9T7D5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9755:HOXA5
gene id: 9755:HOXA5
uniprot id: A0A2Y9F0M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

9755:CENPV
gene id: 9755:CENPV
uniprot id: A0A2Y9SZY0
names: Similarity
messages: Belongs to the Gfa family.

9755:CASS4
gene id: 9755:CASS4
uniprot id: A0A2Y9ELK1
uniprot id: A0A2Y9EN54
uniprot id: A0A2Y9T076
uniprot id: A0A455C1A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

9755:SCARB1
gene id: 9755:SCARB1
uniprot id: A0A2Y9SCY0
uniprot id: A0A2Y9SGS6
uniprot id: A0A2Y9SGT1
uniprot id: A0A2Y9SLG1
uniprot id: A0A455AIT1
uniprot id: A0A455AJ36
names: Similarity
messages: Belongs to the CD36 family.

9755:GIMAP6
gene id: 9755:GIMAP6
uniprot id: A0A2Y9FG31
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

9755:SH3BP5L
gene id: 9755:SH3BP5L
uniprot id: A0A2Y9FB50
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

9755:KCNV2
gene id: 9755:KCNV2
uniprot id: A0A2Y9T110
names: Subcellular Location Annotation
messages: Membrane

9755:P2RX1
gene id: 9755:P2RX1
uniprot id: A0A2Y9FKF2
uniprot id: A0A455BY67
uniprot id: A0A455C219
uniprot id: A0A455CA31
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

9755:GEM
gene id: 9755:GEM
uniprot id: A0A2Y9FEC2
uniprot id: A0A455C4U1
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

9755:MINDY3
gene id: 9755:MINDY3
uniprot id: A0A2Y9EVV7
uniprot id: A0A2Y9EWB6
uniprot id: A0A455BPP9
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
messages: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

9755:ACTL7B
gene id: 9755:ACTL7B
uniprot id: A0A2Y9FDK1
names: Similarity
messages: Belongs to the actin family.

9755:CALCRL
gene id: 9755:CALCRL
uniprot id: A0A2Y9EY64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Heterodimer of CALCRL and RAMP1, RAMP2 or RAMP3.
messages: Membrane
messages: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

9755:NINJ1
gene id: 9755:NINJ1
uniprot id: A0A2Y9S2Z4
uniprot id: A0A2Y9S6M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ninjurin family.
messages: Membrane

9755:SLC24A5
gene id: 9755:SLC24A5
uniprot id: A0A2Y9FCW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

9755:RBP4
gene id: 9755:RBP4
uniprot id: A0A2Y9SF56
uniprot id: A0A2Y9SIX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Interacts with TTR.
messages: Retinol-binding protein that mediates retinol transport in blood plasma.
messages: Secreted

9755:RGS9BP
gene id: 9755:RGS9BP
uniprot id: A0A2Y9EH70
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

9755:FAM120A
gene id: 9755:FAM120A
uniprot id: A0A2Y9SAX6
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

9755:ISL2
gene id: 9755:ISL2
uniprot id: A0A2Y9F0Z8
names: Subcellular Location Annotation
messages: Nucleus

9755:PLBD2
gene id: 9755:PLBD2
uniprot id: A0A455AKH7
names: Function
names: Similarity
messages: Belongs to the phospholipase B-like family.
messages: Putative phospholipase.

9755:LOC102996290
gene id: 9755:LOC102996290
uniprot id: A0A2Y9TAN0
names: Similarity
messages: Belongs to the intermediate filament family.

9755:TDGF1
gene id: 9755:TDGF1
uniprot id: A0A2Y9FL97
names: Caution
names: Similarity
messages: Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:DMRT1
gene id: 9755:DMRT1
uniprot id: A0A2Y9SZB1
uniprot id: A0A455C138
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

9755:ITGA7
gene id: 9755:ITGA7
uniprot id: A0A2Y9FM16
uniprot id: A0A2Y9FN19
uniprot id: A0A455BDI5
uniprot id: A0A455BE56
uniprot id: A0A455BE65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9755:OPHN1
gene id: 9755:OPHN1
uniprot id: A0A2Y9S4L6
uniprot id: A0A455AQ48
uniprot id: A0A455B1V3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Postsynapse
messages: Presynapse
messages: dendrite

9755:LOC102976673
gene id: 9755:LOC102976673
uniprot id: A0A2Y9EII5
names: Similarity
messages: Belongs to the globin family.

9755:ACTN1
gene id: 9755:ACTN1
uniprot id: A0A2Y9RYC3
uniprot id: A0A2Y9S5W0
uniprot id: A0A2Y9S5X1
names: Similarity
messages: Belongs to the alpha-actinin family.

9755:FAM98A
gene id: 9755:FAM98A
uniprot id: A0A2Y9FJD6
uniprot id: A0A2Y9FLF3
names: Similarity
messages: Belongs to the FAM98 family.

9755:BCKDHA
gene id: 9755:BCKDHA
uniprot id: A0A455AD94
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: Together with BCKDHB forms the heterotetrameric E1 subunit of the mitochondrial branched-chain alpha-ketoacid dehydrogenase (BCKD) complex. The BCKD complex catalyzes the multi-step oxidative decarboxylation of alpha-ketoacids derived from the branched-chain amino-acids valine, leucine and isoleucine producing CO2 and acyl-CoA which is subsequently utilized to produce energy. The E1 subunit catalyzes the first step with the decarboxylation of the alpha-ketoacid forming an enzyme-product intermediate. A reductive acylation mediated by the lipoylamide cofactor of E2 extracts the acyl group from the E1 active site for the next step of the reaction.

9755:SLC30A5
gene id: 9755:SLC30A5
uniprot id: A0A2Y9FSX8
uniprot id: A0A455BJ27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Functions as a zinc transporter.
messages: Membrane
messages: trans-Golgi network membrane

9755:TNFSF15
gene id: 9755:TNFSF15
uniprot id: A0A2Y9FC31
names: Similarity
messages: Belongs to the tumor necrosis factor family.

9755:CD8B
gene id: 9755:CD8B
uniprot id: A0A2Y9FB57
names: Subcellular Location Annotation
messages: Membrane

9755:SLC6A15
gene id: 9755:SLC6A15
uniprot id: A0A2Y9FG40
uniprot id: A0A2Y9FG61
uniprot id: A0A2Y9FGG1
uniprot id: A0A2Y9FI72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A15 subfamily.
messages: Membrane

9755:TMEM39B
gene id: 9755:TMEM39B
uniprot id: A0A2Y9FJN3
uniprot id: A0A2Y9FKU1
uniprot id: A0A2Y9FLX5
uniprot id: A0A455B2E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM39 family.
messages: Membrane

9755:MAPKAP1
gene id: 9755:MAPKAP1
uniprot id: A0A2Y9EH68
uniprot id: A0A2Y9EIL1
uniprot id: A0A2Y9SXH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIN1 family.
messages: Cytoplasmic vesicle

9755:ATP10A
gene id: 9755:ATP10A
uniprot id: A0A455BPM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

9755:ARPIN
gene id: 9755:ARPIN
uniprot id: A0A2Y9ENQ7
names: Similarity
messages: Belongs to the Arpin family.

9755:SPTSSA
gene id: 9755:SPTSSA
uniprot id: A0A2Y9SA01
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:CA10
gene id: 9755:CA10
uniprot id: A0A2Y9S766
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Does not have a catalytic activity.

9755:SEMA3E
gene id: 9755:SEMA3E
uniprot id: A0A2Y9ETV9
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:SENP6
gene id: 9755:SENP6
uniprot id: A0A2Y9TCS2
uniprot id: A0A2Y9TGR5
uniprot id: A0A2Y9TGR9
uniprot id: A0A2Y9TIM7
uniprot id: A0A2Y9TIN1
uniprot id: A0A455C3J7
names: Similarity
messages: Belongs to the peptidase C48 family.

9755:SHMT2
gene id: 9755:SHMT2
uniprot id: A0A2Y9EJX7
names: Similarity
messages: Belongs to the SHMT family.

9755:ARHGAP32
gene id: 9755:ARHGAP32
uniprot id: A0A2Y9T9L3
uniprot id: A0A2Y9TB52
names: Similarity
messages: Belongs to the PX domain-containing GAP family.

9755:PRDM16
gene id: 9755:PRDM16
uniprot id: A0A455B713
names: Subcellular Location Annotation
messages: Nucleus

9755:AMD1
gene id: 9755:AMD1
uniprot id: A0A2Y9S1H1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic AdoMetDC family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.
messages: Heterotetramer of two alpha and two beta chains.

9755:CCDC167
gene id: 9755:CCDC167
uniprot id: A0A2Y9FNH2
names: Subcellular Location Annotation
messages: Membrane

9755:CYSLTR1
gene id: 9755:CYSLTR1
uniprot id: A0A2Y9T6K5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9755:LOC102977189
gene id: 9755:LOC102977189
uniprot id: A0A2Y9FAT7
names: Similarity
messages: Belongs to the PRR23 family.

9755:F10
gene id: 9755:F10
uniprot id: A0A2Y9S3S0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9755:AP4E1
gene id: 9755:AP4E1
uniprot id: A0A455BTH6
names: Function
names: Similarity
names: Subunit
messages: Adaptor protein complex 4 (AP-4) is a heterotetramer composed of two large adaptins, a medium adaptin and a small adaptin.
messages: Belongs to the adaptor complexes large subunit family.
messages: Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.

9755:SLC35B3
gene id: 9755:SLC35B3
uniprot id: A0A2Y9EH37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

9755:LOC112064316
gene id: 9755:LOC112064316
uniprot id: A0A2Y9SMB1
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

9755:RXFP2
gene id: 9755:RXFP2
uniprot id: A0A2Y9T0W4
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:ZFYVE26
gene id: 9755:ZFYVE26
uniprot id: A0A2Y9FF84
uniprot id: A0A455BSA6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with AP5Z1, AP5B1, AP5S1 and SPG11. Interacts with TTC19 and KIF13A.
messages: Midbody
messages: Phosphatidylinositol 3-phosphate-binding protein required for the abcission step in cytokinesis: recruited to the midbody during cytokinesis and acts as a regulator of abcission. May also be required for efficient homologous recombination DNA double-strand break repair.

9755:ELF1
gene id: 9755:ELF1
uniprot id: A0A2Y9FCT9
uniprot id: A0A455BXC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9755:LOC102981411
gene id: 9755:LOC102981411
uniprot id: A0A2Y9F747
uniprot id: A0A2Y9RW46
uniprot id: A0A2Y9S3Q4
names: Similarity
messages: Belongs to the cytochrome P450 family.

9755:PTGFR
gene id: 9755:PTGFR
uniprot id: A0A2Y9FEY4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9755:PCMTD1
gene id: 9755:PCMTD1
uniprot id: A0A2Y9EMJ5
uniprot id: A0A2Y9T1M1
uniprot id: A0A455C4Y7
uniprot id: A0A455C591
uniprot id: A0A455C603
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

9755:PDX1
gene id: 9755:PDX1
uniprot id: A0A2Y9SUB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

9755:WASF1
gene id: 9755:WASF1
uniprot id: A0A2Y9RYC7
uniprot id: A0A455BRA1
uniprot id: A0A455C347
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

9755:AKAP4
gene id: 9755:AKAP4
uniprot id: A0A2Y9S241
names: Similarity
messages: Belongs to the AKAP110 family.

9755:GFM1
gene id: 9755:GFM1
uniprot id: A0A2Y9F1H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis.
messages: Mitochondrion

9755:GFRA3
gene id: 9755:GFRA3
uniprot id: A0A2Y9F0X6
names: Similarity
messages: Belongs to the GDNFR family.

9755:LOC102991790
gene id: 9755:LOC102991790
uniprot id: A0A2Y9RXV9
names: Similarity
messages: Belongs to the Speedy/Ringo family.

9755:DCP1B
gene id: 9755:DCP1B
uniprot id: A0A2Y9T1Y4
uniprot id: A0A455BCE3
names: Similarity
messages: Belongs to the DCP1 family.

9755:THBS4
gene id: 9755:THBS4
uniprot id: A0A2Y9STL8
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:ITM2A
gene id: 9755:ITM2A
uniprot id: A0A2Y9F4K1
uniprot id: A0A2Y9F4R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

9755:LOC102979137
gene id: 9755:LOC102979137
uniprot id: A0A455C4H4
uniprot id: A0A455C4H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

9755:GPN3
gene id: 9755:GPN3
uniprot id: A0A455AX03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

9755:RGS4
gene id: 9755:RGS4
uniprot id: A0A2Y9S208
uniprot id: A0A2Y9S5P6
names: Function
messages: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein.

9755:YES1
gene id: 9755:YES1
uniprot id: A0A2Y9ERX0
uniprot id: A0A2Y9ES88
uniprot id: A0A2Y9ETT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

9755:ASPH
gene id: 9755:ASPH
uniprot id: A0A2Y9T3P7
uniprot id: A0A455C500
uniprot id: A0A455C5A0
uniprot id: A0A455C615
uniprot id: A0A455C8Q6
uniprot id: A0A455CBI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.
messages: Membrane

9755:LOC112065033
gene id: 9755:LOC112065033
uniprot id: A0A2Y9SP63
names: Similarity
messages: Belongs to the protein kinase superfamily.

9755:GPR50
gene id: 9755:GPR50
uniprot id: A0A2Y9S5K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9755:DST
gene id: 9755:DST
uniprot id: A0A2Y9ESH7
uniprot id: A0A2Y9ETB6
uniprot id: A0A2Y9SMG0
names: Subcellular Location Annotation
messages: cytoskeleton

9755:LOC102977204
gene id: 9755:LOC102977204
uniprot id: A0A455B219
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NXF family.
messages: Cytoplasm
messages: nucleoplasm

9755:GLS
gene id: 9755:GLS
uniprot id: A0A2Y9F448
uniprot id: A0A2Y9RYH7
uniprot id: A0A2Y9S5B8
uniprot id: A0A2Y9S620
names: Similarity
messages: Belongs to the glutaminase family.

9755:TAS2R41
gene id: 9755:TAS2R41
uniprot id: A0A2Y9T8U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

9755:ADAMTS4
gene id: 9755:ADAMTS4
uniprot id: A0A2Y9EZV7
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9755:ITPKB
gene id: 9755:ITPKB
uniprot id: A0A2Y9EHY7
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

9755:CEP57L1
gene id: 9755:CEP57L1
uniprot id: A0A2Y9EDT6
names: Similarity
messages: Belongs to the translokin family.

9755:HHEX
gene id: 9755:HHEX
uniprot id: A0A2Y9SLE1
names: Subcellular Location Annotation
messages: Nucleus

9755:AKR1E2
gene id: 9755:AKR1E2
uniprot id: A0A2Y9T585
names: Similarity
messages: Belongs to the aldo/keto reductase family.

9755:HIGD1C
gene id: 9755:HIGD1C
uniprot id: A0A2Y9SJS1
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

9755:ERRFI1
gene id: 9755:ERRFI1
uniprot id: A0A2Y9SUK5
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus

9755:CACNG3
gene id: 9755:CACNG3
uniprot id: A0A2Y9EMX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane

9755:LOC114486216
gene id: 9755:LOC114486216
uniprot id: A0A455BM28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the RNA polymerase II complex. Interacts with transcribing RNA polymerase II phosphorylated on 'Ser-7' on CTD.
messages: Belongs to the RPAP2 family.
messages: Nucleus
messages: Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated 'Ser-7' of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of 'Ser-5' of the CTD, thereby promoting transcription of snRNA genes.

9755:RASGRP3
gene id: 9755:RASGRP3
uniprot id: A0A455C8Y1
names: Similarity
messages: Belongs to the RASGRP family.

9755:UFM1
gene id: 9755:UFM1
uniprot id: A0A2Y9F802
uniprot id: A0A2Y9F890
names: Function
names: Similarity
messages: Belongs to the UFM1 family.
messages: Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to lysine residues of substrate proteins as a monomer or a lysine-linked polymer. Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.

9755:RAP1GDS1
gene id: 9755:RAP1GDS1
uniprot id: A0A2Y9EVB2
uniprot id: A0A2Y9EX59
uniprot id: A0A2Y9SVW6
uniprot id: A0A2Y9T2M5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Mitochondrion

9755:NONO
gene id: 9755:NONO
uniprot id: A0A2Y9FG20
uniprot id: A0A455AQC5
names: Subcellular Location Annotation
messages: Nucleus speckle

9755:ACTL7A
gene id: 9755:ACTL7A
uniprot id: A0A2Y9FD60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Golgi apparatus
messages: May play an important role in formation and fusion of Golgi-derived vesicles during acrosome biogenesis.
messages: Nucleus
messages: cytoskeleton

9755:EPN3
gene id: 9755:EPN3
uniprot id: A0A2Y9EJE8
names: Similarity
messages: Belongs to the epsin family.

9755:PCYT1B
gene id: 9755:PCYT1B
uniprot id: A0A2Y9RWS7
names: Function
names: Similarity
messages: Belongs to the cytidylyltransferase family.
messages: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.

9755:TEKT2
gene id: 9755:TEKT2
uniprot id: A0A2Y9T069
uniprot id: A0A455B0S6
uniprot id: A0A455BDN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

9755:SP4
gene id: 9755:SP4
uniprot id: A0A2Y9FDZ5
uniprot id: A0A455BAB2
uniprot id: A0A455BB41
uniprot id: A0A455BD91
uniprot id: A0A455BPX1
names: Subcellular Location Annotation
messages: Nucleus

9755:TRAPPC11
gene id: 9755:TRAPPC11
uniprot id: A0A2Y9EEV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPPC11 family.
messages: Involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage.
messages: cis-Golgi network

9755:BABAM2
gene id: 9755:BABAM2
uniprot id: A0A455C8N2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BABAM2 family.
messages: Component of the ARISC complex. Component of the BRCA1-A complex. Component of the BRISC complex. Binds polyubiquitin.
messages: Contains 2 ubiquitin-conjugating enzyme family-like (UEV-like) regions. These regions lack the critical Cys residues required for ubiquitination but retain the ability to bind ubiquitin.
messages: Cytoplasm
messages: May play a role in homeostasis or cellular differentiation in cells of neural, epithelial and germline origins. May also act as a death receptor-associated anti-apoptotic protein, which inhibits the mitochondrial apoptotic pathway.
messages: Nucleus

9755:TSN
gene id: 9755:TSN
uniprot id: A0A2Y9FL57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the translin family.
messages: DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots.
messages: Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand.
messages: Nucleus
messages: Ring-shaped heterooctamer of six TSN and two TSNAX subunits, DNA/RNA binding occurs inside the ring.

9755:LOC102975327
gene id: 9755:LOC102975327
uniprot id: A0A2Y9SS19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of mevalonate to mevalonate 5-phosphate, a key step in isoprenoid and cholesterol biosynthesis.
messages: Cytoplasm

9755:DOCK9
gene id: 9755:DOCK9
uniprot id: A0A2Y9SRA1
uniprot id: A0A2Y9SRB1
uniprot id: A0A2Y9ST72
uniprot id: A0A455BVN0
uniprot id: A0A455BVN1
uniprot id: A0A455BVN4
uniprot id: A0A455BVN6
uniprot id: A0A455BVN9
uniprot id: A0A455BVP6
uniprot id: A0A455BWC5
uniprot id: A0A455BWD0
uniprot id: A0A455BZ50
uniprot id: A0A455BZ55
uniprot id: A0A455BZ60
uniprot id: A0A455BZ65
uniprot id: A0A455C993
uniprot id: A0A455C995
uniprot id: A0A455C997
names: Similarity
messages: Belongs to the DOCK family.

9755:FTMT
gene id: 9755:FTMT
uniprot id: A0A2Y9F6L6
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

9755:FASLG
gene id: 9755:FASLG
uniprot id: A0A2Y9ERD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Cell membrane
messages: Cytoplasmic form induces gene transcription inhibition.
messages: Cytoplasmic vesicle lumen
messages: Lysosome lumen
messages: Nucleus
messages: Secreted

9755:ACTRT3
gene id: 9755:ACTRT3
uniprot id: A0A2Y9EZU5
names: Similarity
messages: Belongs to the actin family.

9755:PRICKLE2
gene id: 9755:PRICKLE2
uniprot id: A0A2Y9EEY6
uniprot id: A0A2Y9EFM2
uniprot id: A0A2Y9EGQ3
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

9755:PPFIA2
gene id: 9755:PPFIA2
uniprot id: A0A2Y9SSB6
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

9755:KCNMB3
gene id: 9755:KCNMB3
uniprot id: A0A455BH62
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KCNMB (TC 8.A.14.1) family.
messages: Interacts with KCNMA1 tetramer. There are probably 4 molecules of KCMNB per KCNMA1 tetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-glycosylated.
messages: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity.

9755:SMAGP
gene id: 9755:SMAGP
uniprot id: A0A2Y9SS27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAGP family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane

9755:PANX1
gene id: 9755:PANX1
uniprot id: A0A2Y9FJ50
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: S-nitrosylation inhibits channel currents and ATP release.
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

9755:LOC112067635
gene id: 9755:LOC112067635
uniprot id: A0A2Y9TGF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

9755:LAMP5
gene id: 9755:LAMP5
uniprot id: A0A2Y9EUS1
uniprot id: A0A2Y9EW40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane
messages: Membrane

9755:SCAMP4
gene id: 9755:SCAMP4
uniprot id: A0A455C5B3
uniprot id: A0A455C8R1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:LOC102989113
gene id: 9755:LOC102989113
uniprot id: A0A2Y9F5V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:GTF2H1
gene id: 9755:GTF2H1
uniprot id: A0A2Y9EM99
uniprot id: A0A455C9Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB1 family.
messages: Nucleus

9755:APMAP
gene id: 9755:APMAP
uniprot id: A0A455C025
names: Similarity
messages: Belongs to the strictosidine synthase family.

9755:SCG3
gene id: 9755:SCG3
uniprot id: A0A2Y9F3M2
names: Subcellular Location Annotation
messages: Membrane
messages: Secreted
messages: secretory vesicle membrane

9755:HMGN3
gene id: 9755:HMGN3
uniprot id: A0A2Y9FNH6
uniprot id: A0A2Y9FQD5
uniprot id: A0A455BQ66
uniprot id: A0A455BQ83
uniprot id: A0A455BTI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

9755:NRXN3
gene id: 9755:NRXN3
uniprot id: A0A2Y9S6F9
uniprot id: A0A2Y9S6N7
uniprot id: A0A2Y9SD15
uniprot id: A0A2Y9SEI5
uniprot id: A0A455BST5
uniprot id: A0A455BTH2
uniprot id: A0A455BW76
uniprot id: A0A455C7Z2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Presynaptic cell membrane

9755:NIPA1
gene id: 9755:NIPA1
uniprot id: A0A2Y9SAP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

9755:HOXA6
gene id: 9755:HOXA6
uniprot id: A0A2Y9F2L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

9755:CRY2
gene id: 9755:CRY2
uniprot id: A0A2Y9FLN7
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 FAD per subunit.

9755:DOT1L
gene id: 9755:DOT1L
uniprot id: A0A2Y9TL10
uniprot id: A0A2Y9TL50
uniprot id: A0A2Y9TL52
uniprot id: A0A455C660
uniprot id: A0A455C8S7
uniprot id: A0A455CBK7
uniprot id: A0A455CBK9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.
messages: Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.
messages: Histone methyltransferase. Methylates 'Lys-79' of histone H3.
messages: In contrast to other lysine histone methyltransferases, it does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones.
messages: Nucleus

9755:KIF2B
gene id: 9755:KIF2B
uniprot id: A0A2Y9SYF9
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:HOXC6
gene id: 9755:HOXC6
uniprot id: A0A2Y9FN40
uniprot id: A0A2Y9SJ86
uniprot id: A0A2Y9SQ38
uniprot id: A0A2Y9SRY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

9755:SEC61B
gene id: 9755:SEC61B
uniprot id: A0A2Y9FE28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC61-beta family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Necessary for protein translocation in the endoplasmic reticulum.

9755:MAP6
gene id: 9755:MAP6
uniprot id: A0A2Y9EH43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STOP family.
messages: cytoskeleton

9755:LOC102973941
gene id: 9755:LOC102973941
uniprot id: A0A2Y9S789
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:VPS13B
gene id: 9755:VPS13B
uniprot id: A0A2Y9S2H8
uniprot id: A0A2Y9S656
uniprot id: A0A455C3J5
uniprot id: A0A455C3U3
uniprot id: A0A455C7Y7
names: Similarity
messages: Belongs to the VPS13 family.

9755:GFM2
gene id: 9755:GFM2
uniprot id: A0A2Y9ETM9
uniprot id: A0A2Y9EU42
uniprot id: A0A2Y9EU51
uniprot id: A0A2Y9EUR1
uniprot id: A0A455BJ47
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
messages: Mitochondrion

9755:ATP5PD
gene id: 9755:ATP5PD
uniprot id: A0A2Y9ECA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase d subunit family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion inner membrane

9755:TYRP1
gene id: 9755:TYRP1
uniprot id: A0A2Y9EW91
uniprot id: A0A2Y9EY58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

9755:SLC12A3
gene id: 9755:SLC12A3
uniprot id: A0A455ABA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

9755:ARL6IP5
gene id: 9755:ARL6IP5
uniprot id: A0A2Y9EPZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

9755:BROX
gene id: 9755:BROX
uniprot id: A0A2Y9ET22
uniprot id: A0A455BJS1
names: Similarity
messages: Belongs to the BROX family.

9755:MCOLN2
gene id: 9755:MCOLN2
uniprot id: A0A2Y9SA75
uniprot id: A0A2Y9SHX1
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

9755:MSH5
gene id: 9755:MSH5
uniprot id: A0A2Y9EW42
uniprot id: A0A455ADP8
uniprot id: A0A455AEV6
uniprot id: A0A455AFS0
uniprot id: A0A455AFS5
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.

9755:ATP5PO
gene id: 9755:ATP5PO
uniprot id: A0A2Y9FKK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion inner membrane

9755:LOC102994026
gene id: 9755:LOC102994026
uniprot id: A0A2Y9S6H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:LOC102977964
gene id: 9755:LOC102977964
uniprot id: A0A2Y9TIE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:DDX28
gene id: 9755:DDX28
uniprot id: A0A2Y9FG67
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

9755:UBE2D1
gene id: 9755:UBE2D1
uniprot id: A0A455AL09
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9755:MRPL36
gene id: 9755:MRPL36
uniprot id: A0A2Y9SM31
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

9755:ADCY3
gene id: 9755:ADCY3
uniprot id: A0A455BUV8
uniprot id: A0A455C8Y6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

9755:ADAM23
gene id: 9755:ADAM23
uniprot id: A0A2Y9SP56
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:AMER1
gene id: 9755:AMER1
uniprot id: A0A2Y9FIH2
names: Similarity
messages: Belongs to the Amer family.

9755:KIT
gene id: 9755:KIT
uniprot id: A0A2Y9FEQ2
uniprot id: A0A2Y9FET5
uniprot id: A0A2Y9FEW7
uniprot id: A0A2Y9FGN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Membrane

9755:NFASC
gene id: 9755:NFASC
uniprot id: A0A2Y9FUK1
uniprot id: A0A2Y9FUP4
uniprot id: A0A2Y9FWM7
uniprot id: A0A455B4M9
names: Similarity
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.

9755:LOC114487540
gene id: 9755:LOC114487540
uniprot id: A0A455C9Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cystatin family.
messages: Secreted

9755:POLB
gene id: 9755:POLB
uniprot id: A0A2Y9FNF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Cytoplasm
messages: DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
messages: Nucleus

9755:PBX3
gene id: 9755:PBX3
uniprot id: A0A2Y9T050
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

9755:DYDC2
gene id: 9755:DYDC2
uniprot id: A0A2Y9EZJ6
names: Similarity
messages: Belongs to the dpy-30 family.

9755:LOC102986053
gene id: 9755:LOC102986053
uniprot id: A0A2Y9TA94
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

9755:LTN1
gene id: 9755:LTN1
uniprot id: A0A2Y9SHY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LTN1 family.
messages: Component of the ribosome quality control complex (RQC).
messages: E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.
messages: cytosol

9755:ATP9B
gene id: 9755:ATP9B
uniprot id: A0A2Y9TKM2
uniprot id: A0A455AXA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

9755:TALDO1
gene id: 9755:TALDO1
uniprot id: A0A2Y9T9D3
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.

9755:MYO15A
gene id: 9755:MYO15A
uniprot id: A0A455BYS9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

9755:GPN1
gene id: 9755:GPN1
uniprot id: A0A2Y9FH34
uniprot id: A0A455BTS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II.
messages: Cytoplasm
messages: Nucleus
messages: Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.

9755:MYOD1
gene id: 9755:MYOD1
uniprot id: A0A2Y9F383
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.
messages: Nucleus

9755:ENPP1
gene id: 9755:ENPP1
uniprot id: A0A2Y9SIX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
messages: Secreted

9755:CEP55
gene id: 9755:CEP55
uniprot id: A0A2Y9EQI3
uniprot id: A0A2Y9ER58
names: Subcellular Location Annotation
messages: Cytoplasm

9755:EIF4A2
gene id: 9755:EIF4A2
uniprot id: A0A2Y9F6P4
uniprot id: A0A2Y9F709
uniprot id: A0A2Y9F7I1
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

9755:ORC2
gene id: 9755:ORC2
uniprot id: A0A2Y9ETW7
uniprot id: A0A455AXC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC2 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Component of the origin recognition complex (ORC).
messages: Nucleus

9755:BSX
gene id: 9755:BSX
uniprot id: A0A2Y9FRD4
names: Subcellular Location Annotation
messages: Nucleus

9755:AATF
gene id: 9755:AATF
uniprot id: A0A2Y9EEI2
uniprot id: A0A455C391
names: Similarity
messages: Belongs to the AATF family.

9755:ELP1
gene id: 9755:ELP1
uniprot id: A0A2Y9SX32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP1/IKA1 family.
messages: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
messages: Cytoplasm
messages: Nucleus

9755:SLC10A7
gene id: 9755:SLC10A7
uniprot id: A0A2Y9SVZ8
uniprot id: A0A2Y9SW03
uniprot id: A0A2Y9SYG7
uniprot id: A0A2Y9T0K1
uniprot id: A0A2Y9T2Q2
uniprot id: A0A455BEZ4
uniprot id: A0A455BFH9
uniprot id: A0A455BFM2
uniprot id: A0A455BI11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Cell membrane
messages: Does not show transport activity towards bile acids or steroid sulfates.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

9755:THOC6
gene id: 9755:THOC6
uniprot id: A0A2Y9ECU8
uniprot id: A0A2Y9EDC5
names: Similarity
messages: Belongs to the WD repeat THOC6 family.

9755:PSMC6
gene id: 9755:PSMC6
uniprot id: A0A2Y9FDM5
names: Similarity
messages: Belongs to the AAA ATPase family.

9755:PMEL
gene id: 9755:PMEL
uniprot id: A0A2Y9FRS1
uniprot id: A0A2Y9FRS6
uniprot id: A0A2Y9FTP2
uniprot id: A0A2Y9FUJ1
names: Similarity
messages: Belongs to the PMEL/NMB family.

9755:LOC102991591
gene id: 9755:LOC102991591
uniprot id: A0A455BH83
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:SUCLG2
gene id: 9755:SUCLG2
uniprot id: A0A2Y9SSZ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family. GTP-specific subunit beta subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
messages: Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for GTP.
messages: Mitochondrion

9755:NCEH1
gene id: 9755:NCEH1
uniprot id: A0A2Y9FAA9
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

9755:ABHD3
gene id: 9755:ABHD3
uniprot id: A0A2Y9FQ59
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

9755:HAGH
gene id: 9755:HAGH
uniprot id: A0A2Y9SLC8
uniprot id: A0A2Y9STW0
uniprot id: A0A455BYI9
uniprot id: A0A455BYJ8
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

9755:EDN3
gene id: 9755:EDN3
uniprot id: A0A2Y9T434
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

9755:LOC102990890
gene id: 9755:LOC102990890
uniprot id: A0A455C284
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.

9755:SLC30A6
gene id: 9755:SLC30A6
uniprot id: A0A2Y9EIY7
uniprot id: A0A2Y9S7Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

9755:STN1
gene id: 9755:STN1
uniprot id: A0A2Y9FU33
uniprot id: A0A455ALT9
uniprot id: A0A455ANM3
uniprot id: A0A455ANX3
uniprot id: A0A455B0K4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the STN1 family.
messages: Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.
messages: Component of the CST complex.
messages: Nucleus
messages: telomere

9755:LOC102975860
gene id: 9755:LOC102975860
uniprot id: A0A2Y9F4Z3
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

9755:LRRFIP2
gene id: 9755:LRRFIP2
uniprot id: A0A455AG40
uniprot id: A0A455AGJ9
uniprot id: A0A455AHX4
uniprot id: A0A455AIB2
uniprot id: A0A455AIB7
uniprot id: A0A455AIC4
uniprot id: A0A455AU53
uniprot id: A0A455AU61
names: Similarity
messages: Belongs to the LRRFIP family.

9755:GABRD
gene id: 9755:GABRD
uniprot id: A0A2Y9SSR9
uniprot id: A0A2Y9SV44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9755:TMEM129
gene id: 9755:TMEM129
uniprot id: A0A2Y9F313
uniprot id: A0A2Y9F329
uniprot id: A0A2Y9F3B0
uniprot id: A0A2Y9F440
uniprot id: A0A455BH15
uniprot id: A0A455BHG0
uniprot id: A0A455BK34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM129 family.
messages: Membrane

9755:CFAP45
gene id: 9755:CFAP45
uniprot id: A0A2Y9FSD7
names: Similarity
messages: Belongs to the CFAP45 family.

9755:OLFM3
gene id: 9755:OLFM3
uniprot id: A0A2Y9EWD3
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

9755:MIS12
gene id: 9755:MIS12
uniprot id: A0A2Y9EI68
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mis12 family.
messages: Component of the MIS12 complex composed of MIS12, DSN1, NSL1 and PMF1. Also interacts with KNL1, CBX3, CBX5, NDC80 and ZWINT.
messages: kinetochore

9755:NDUFC2
gene id: 9755:NDUFC2
uniprot id: A0A2Y9EQZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFC2 subunit family.
messages: Mitochondrion inner membrane

9755:CCDC90B
gene id: 9755:CCDC90B
uniprot id: A0A2Y9TAR5
uniprot id: A0A2Y9TCA2
names: Similarity
messages: Belongs to the CCDC90 family.

9755:GDF2
gene id: 9755:GDF2
uniprot id: A0A2Y9FAZ5
names: Similarity
messages: Belongs to the TGF-beta family.

9755:LOC102982837
gene id: 9755:LOC102982837
uniprot id: A0A2Y9FGS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

9755:CXCL9
gene id: 9755:CXCL9
uniprot id: A0A2Y9FH65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

9755:ADAMTS10
gene id: 9755:ADAMTS10
uniprot id: A0A2Y9TIP4
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9755:LOC102993099
gene id: 9755:LOC102993099
uniprot id: A0A2Y9EHQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COA3 family.
messages: Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.
messages: Core component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly.
messages: Membrane
messages: Required for assembly of cytochrome c oxidase (complex IV).

9755:LOC102987082
gene id: 9755:LOC102987082
uniprot id: A0A455C342
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. ICAM family.
messages: Membrane

9755:FOLR2
gene id: 9755:FOLR2
uniprot id: A0A2Y9F0Y7
names: Similarity
messages: Belongs to the folate receptor family.

9755:PAX9
gene id: 9755:PAX9
uniprot id: A0A2Y9EN18
uniprot id: A0A2Y9EN59
names: Subcellular Location Annotation
messages: Nucleus

9755:ERGIC3
gene id: 9755:ERGIC3
uniprot id: A0A2Y9EGZ4
uniprot id: A0A455C1B2
uniprot id: A0A455C1B3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

9755:DBX1
gene id: 9755:DBX1
uniprot id: A0A2Y9FHC7
names: Subcellular Location Annotation
messages: Nucleus

9755:DSE
gene id: 9755:DSE
uniprot id: A0A2Y9EV15
uniprot id: A0A2Y9EW57
uniprot id: A0A2Y9RXU7
uniprot id: A0A2Y9S5B4
names: Similarity
messages: Belongs to the dermatan-sulfate isomerase family.

9755:KCTD13
gene id: 9755:KCTD13
uniprot id: A0A2Y9ER85
uniprot id: A0A2Y9ESS3
names: Similarity
messages: Belongs to the BACURD family.

9755:LOC102982571
gene id: 9755:LOC102982571
uniprot id: A0A2Y9EMB1
uniprot id: A0A455C934
names: Similarity
messages: Belongs to the cytochrome P450 family.

9755:RPL10L
gene id: 9755:RPL10L
uniprot id: A0A2Y9EM19
uniprot id: A0A2Y9ENF2
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

9755:LOC102990478
gene id: 9755:LOC102990478
uniprot id: A0A455AC35
uniprot id: A0A455AD91
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

9755:PDPK1
gene id: 9755:PDPK1
uniprot id: A0A455BXP6
uniprot id: A0A455BXP9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.

9755:CDCA7L
gene id: 9755:CDCA7L
uniprot id: A0A2Y9EYI3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9755:MYO1E
gene id: 9755:MYO1E
uniprot id: A0A2Y9FQD6
uniprot id: A0A455BX01
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

9755:CST9L
gene id: 9755:CST9L
uniprot id: A0A455C0X1
uniprot id: A0A455C0X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cystatin family.
messages: Secreted

9755:VLDLR
gene id: 9755:VLDLR
uniprot id: A0A2Y9SV02
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:LOC102976516
gene id: 9755:LOC102976516
uniprot id: A0A2Y9EVD8
names: Subcellular Location Annotation
messages: Membrane

9755:HNRNPH1
gene id: 9755:HNRNPH1
uniprot id: A0A2Y9F0G0
uniprot id: A0A2Y9F0L6
uniprot id: A0A2Y9F0U5
uniprot id: A0A2Y9F0V0
uniprot id: A0A2Y9F1P1
uniprot id: A0A2Y9F2F0
uniprot id: A0A2Y9S876
uniprot id: A0A455BYB1
uniprot id: A0A455BYB6
uniprot id: A0A455BYC9
uniprot id: A0A455BYD9
names: Subcellular Location Annotation
messages: nucleoplasm

9755:GUCY2C
gene id: 9755:GUCY2C
uniprot id: A0A2Y9ERQ2
uniprot id: A0A2Y9ES29
uniprot id: A0A455BDM5
uniprot id: A0A455BG10
uniprot id: A0A455BSK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

9755:SUPV3L1
gene id: 9755:SUPV3L1
uniprot id: A0A2Y9FEI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family.
messages: mitochondrion nucleoid

9755:MAP2K1
gene id: 9755:MAP2K1
uniprot id: A0A2Y9FRV8
names: Similarity
messages: Belongs to the protein kinase superfamily.

9755:SFR1
gene id: 9755:SFR1
uniprot id: A0A2Y9F242
uniprot id: A0A2Y9F308
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFR1/MEI5 family.
messages: Nucleus

9755:KEF67 p13
gene id: 9755:KEF67_p13
uniprot id: Q9MET6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 1 family.
messages: Membrane
messages: Mitochondrion inner membrane

9755:LOC102987726
gene id: 9755:LOC102987726
uniprot id: A0A2Y9EEJ7
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

9755:CAPN14
gene id: 9755:CAPN14
uniprot id: A0A2Y9FPB4
names: Similarity
messages: Belongs to the peptidase C2 family.

9755:SLC26A9
gene id: 9755:SLC26A9
uniprot id: A0A2Y9F346
uniprot id: A0A2Y9TJ28
uniprot id: A0A2Y9TKD7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Ion transporter that can act both as an ion channel and anion exchanger. Mainly acts as a chloride channel, which mediate uncoupled chloride anion transport in an alternate-access mechanism where a saturable binding site is alternately exposed to either one or the other side of the membrane. Also acts as a DIDS- and thiosulfate- sensitive anion exchanger the exchange of chloride for bicarbonate ions across the cell membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:KIFC3
gene id: 9755:KIFC3
uniprot id: A0A2Y9SW10
uniprot id: A0A455AB71
uniprot id: A0A455ABB0
uniprot id: A0A455ADE1
uniprot id: A0A455AMW8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9755:LOC102989593
gene id: 9755:LOC102989593
uniprot id: A0A2Y9TH45
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

9755:EDN2
gene id: 9755:EDN2
uniprot id: A0A2Y9F0R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

9755:ZDHHC4
gene id: 9755:ZDHHC4
uniprot id: A0A455C6V3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9755:MIOS
gene id: 9755:MIOS
uniprot id: A0A2Y9EQ84
uniprot id: A0A455BAN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat mio family.
messages: Lysosome membrane

9755:LOC112063771
gene id: 9755:LOC112063771
uniprot id: A0A2Y9SA39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX16 family.
messages: Membrane
messages: Mitochondrion inner membrane

9755:TRAK2
gene id: 9755:TRAK2
uniprot id: A0A2Y9F111
uniprot id: A0A2Y9SX55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the milton family.
messages: Early endosome
messages: Mitochondrion

9755:KCTD20
gene id: 9755:KCTD20
uniprot id: A0A2Y9EMG6
names: Subcellular Location Annotation
messages: Cytoplasm

9755:LOC114486229
gene id: 9755:LOC114486229
uniprot id: A0A455B876
names: Subcellular Location Annotation
messages: Nucleus

9755:TMEM106B
gene id: 9755:TMEM106B
uniprot id: A0A2Y9F2S9
names: Similarity
messages: Belongs to the TMEM106 family.

9755:LOC102978003
gene id: 9755:LOC102978003
uniprot id: A0A2Y9TI03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Membrane
messages: Microsome membrane

9755:PCNX4
gene id: 9755:PCNX4
uniprot id: A0A2Y9FHZ6
uniprot id: A0A2Y9THX8
uniprot id: A0A455BVE6
uniprot id: A0A455C762
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9755:VIRMA
gene id: 9755:VIRMA
uniprot id: A0A2Y9F9A6
uniprot id: A0A2Y9S2I2
names: Similarity
messages: Belongs to the vir family.

9755:LOC102988221
gene id: 9755:LOC102988221
uniprot id: A0A455AJ00
names: Similarity
messages: Belongs to the serpin family. Ov-serpin subfamily.

9755:KCMF1
gene id: 9755:KCMF1
uniprot id: A0A2Y9T7G7
names: Function
names: Similarity
messages: Belongs to the KCMF1 family.
messages: Has intrinsic E3 ubiquitin ligase activity and promotes ubiquitination.

9755:NEUROD4
gene id: 9755:NEUROD4
uniprot id: A0A2Y9FKT4
names: Subcellular Location Annotation
messages: Nucleus

9755:TMEM150C
gene id: 9755:TMEM150C
uniprot id: A0A2Y9RX45
names: Subcellular Location Annotation
messages: Membrane

9755:PMS1
gene id: 9755:PMS1
uniprot id: A0A2Y9F910
uniprot id: A0A455AH69
uniprot id: A0A455AH83
uniprot id: A0A455AHN4
uniprot id: A0A455AJ40
uniprot id: A0A455AJ54
uniprot id: A0A455AVE7
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

9755:LOC112063963
gene id: 9755:LOC112063963
uniprot id: A0A2Y9SAY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

9755:AASS
gene id: 9755:AASS
uniprot id: A0A2Y9SZG2
uniprot id: A0A2Y9T112
names: Similarity
messages: In the C-terminal section; belongs to the saccharopine dehydrogenase family.
messages: In the N-terminal section; belongs to the AlaDH/PNT family.

9755:SYNE3
gene id: 9755:SYNE3
uniprot id: A0A455BWJ7
names: Similarity
messages: Belongs to the nesprin family.

9755:SFT2D1
gene id: 9755:SFT2D1
uniprot id: A0A2Y9ETR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

9755:SGPL1
gene id: 9755:SGPL1
uniprot id: A0A455ALB9
names: Similarity
messages: Belongs to the group II decarboxylase family.

9755:SEPTIN2
gene id: 9755:SEPTIN2
uniprot id: A0A2Y9FP77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Filament-forming cytoskeletal GTPase.
messages: Midbody
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.
messages: cilium membrane
messages: flagellum
messages: spindle

9755:UPP2
gene id: 9755:UPP2
uniprot id: A0A2Y9SHL0
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

9755:PTPN12
gene id: 9755:PTPN12
uniprot id: A0A2Y9S6C2
uniprot id: A0A455BB08
uniprot id: A0A455BDF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 4 subfamily.
messages: Cytoplasm
messages: Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades.

9755:GPR161
gene id: 9755:GPR161
uniprot id: A0A455B6C4
uniprot id: A0A455B6R7
uniprot id: A0A455B782
uniprot id: A0A455B938
uniprot id: A0A455BKS1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9755:ARL5B
gene id: 9755:ARL5B
uniprot id: A0A2Y9F0T3
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

9755:SMARCAD1
gene id: 9755:SMARCAD1
uniprot id: A0A2Y9EDR8
uniprot id: A0A2Y9EEZ7
names: Subcellular Location Annotation
messages: Chromosome

9755:LETMD1
gene id: 9755:LETMD1
uniprot id: A0A2Y9F2D9
uniprot id: A0A2Y9SQR5
uniprot id: A0A455BDT3
uniprot id: A0A455BTG6
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

9755:MCM2
gene id: 9755:MCM2
uniprot id: A0A455ARU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Chromosome
messages: Nucleus

9755:SNAP25
gene id: 9755:SNAP25
uniprot id: A0A2Y9EG20
uniprot id: A0A2Y9EH84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Membrane
messages: Part of the SNARE core complex containing SNAP25, VAMP2 and STX1A; this complex binds CPLX1. Found in a complex containing SYT1, SV2B and syntaxin-1. Found in a ternary complex with STX1A and VAMP8. Interacts with HSC70 and with SYT9, forming a complex with DNAJC5. The interaction with SYT9 is inhibited in presence of calcium. Isoform 1 and isoform 2 interact with BLOC1S6. Interacts with CENPF. Interacts with EQTN. Interacts with HGS. Interacts with KCNB1 (via N-terminus); reduces the voltage-dependent potassium channel KCNB1 activity in pancreatic beta cells. Interacts with OTOF. Interacts with RIMS1. Interacts with SNAPIN. Interacts with STXBP6. Interacts with TRIM9. Interacts with ZDHHC13 (via ANK repeats). Interacts with ZDHHC17 (via ANK repeats). Associates with the BLOC-1 complex. Interacts with PLCL1 (via C2 domain). Interacts with PRRT2; this interaction may impair the formation of the SNARE complex. Interacts with alpha-synuclein/SNCA. Interacts with PRPH2. Interacts with ROM1. Interacts with STX3.
messages: Photoreceptor inner segment
messages: synaptosome
messages: t-SNARE involved in the molecular regulation of neurotransmitter release. Plays an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells.

9755:LOC102986713
gene id: 9755:LOC102986713
uniprot id: A0A2Y9EMK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the serpin family. Ov-serpin subfamily.
messages: extracellular space

9755:TOMM20L
gene id: 9755:TOMM20L
uniprot id: A0A2Y9TGR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

9755:TACC3
gene id: 9755:TACC3
uniprot id: A0A2Y9S955
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

9755:CHRM5
gene id: 9755:CHRM5
uniprot id: A0A2Y9FP07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

9755:PANK4
gene id: 9755:PANK4
uniprot id: A0A2Y9T097
uniprot id: A0A455B4A9
uniprot id: A0A455BIK5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activity is strongly promoted by Co(2+), Ni(2+), Mg(2+) and Mn(2+). Activity is inhibited by EDTA.
messages: Belongs to the type II pantothenate kinase family.
messages: Cytoplasm
messages: Homodimer. Interacts with PKM.
messages: In the N-terminal section; belongs to the type II pantothenate kinase family.
messages: Phosphatase which shows a preference for 4'-phosphopantetheine and its oxidatively damaged forms (sulfonate or S-sulfonate), providing strong indirect evidence that the phosphatase activity pre-empts damage in the coenzyme A (CoA) pathway. Hydrolyzing excess 4'-phosphopantetheine could constitute a directed overflow mechanism to prevent its oxidation to the S-sulfonate, sulfonate, or other forms. Hydrolyzing 4'-phosphopantetheine sulfonate or S-sulfonate would forestall their conversion to inactive forms of CoA and acyl carrier protein. May play a role in the physiological regulation of CoA intracellular levels.

9755:LOC102985822
gene id: 9755:LOC102985822
uniprot id: A0A2Y9SK75
uniprot id: A0A2Y9SN57
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

9755:EN2
gene id: 9755:EN2
uniprot id: A0A2Y9T2E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Engrailed homeobox family.
messages: Nucleus

9755:GABRA6
gene id: 9755:GABRA6
uniprot id: A0A2Y9FAF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9755:TSPAN12
gene id: 9755:TSPAN12
uniprot id: A0A2Y9FB14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9755:SUMF1
gene id: 9755:SUMF1
uniprot id: A0A2Y9SM12
uniprot id: A0A2Y9SMX9
uniprot id: A0A2Y9SV65
uniprot id: A0A455AEV3
uniprot id: A0A455AFB5
uniprot id: A0A455AGM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase-modifying factor family.
messages: Endoplasmic reticulum lumen

9755:MRPS30
gene id: 9755:MRPS30
uniprot id: A0A2Y9FSK9
uniprot id: A0A455BIW8
names: Subcellular Location Annotation
messages: Mitochondrion

9755:SLC39A10
gene id: 9755:SLC39A10
uniprot id: A0A2Y9F6A5
names: Subcellular Location Annotation
messages: Membrane

9755:B3GALT5
gene id: 9755:B3GALT5
uniprot id: A0A2Y9EYM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9755:ACAD9
gene id: 9755:ACAD9
uniprot id: A0A2Y9EVG9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

9755:SLC35C2
gene id: 9755:SLC35C2
uniprot id: A0A2Y9F5F1
uniprot id: A0A2Y9T3Y1
names: Subcellular Location Annotation
messages: Membrane

9755:LOC102995688
gene id: 9755:LOC102995688
uniprot id: A0A2Y9SKS8
names: Similarity
messages: Belongs to the peptidase M16 family.

9755:LOC102977966
gene id: 9755:LOC102977966
uniprot id: A0A2Y9FF54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase VIIb family.
messages: Membrane
messages: Mitochondrion inner membrane

9755:TNS2
gene id: 9755:TNS2
uniprot id: A0A2Y9FKY5
uniprot id: A0A2Y9FLB2
uniprot id: A0A2Y9SMS3
uniprot id: A0A2Y9SSN2
uniprot id: A0A455BDQ2
uniprot id: A0A455BDQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTEN phosphatase protein family.
messages: focal adhesion

9755:TLR8
gene id: 9755:TLR8
uniprot id: A0A2Y9FF09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

9755:ARHGAP26
gene id: 9755:ARHGAP26
uniprot id: A0A2Y9SAB1
uniprot id: A0A2Y9SEQ6
uniprot id: A0A455BMN1
uniprot id: A0A455BZD1
names: Subcellular Location Annotation
messages: cytoskeleton
messages: focal adhesion

9755:OTX2
gene id: 9755:OTX2
uniprot id: A0A2Y9EFM3
uniprot id: A0A2Y9EGB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

9755:GPR146
gene id: 9755:GPR146
uniprot id: A0A455C3B7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9755:TRIP13
gene id: 9755:TRIP13
uniprot id: A0A2Y9SV60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AAA ATPase family. PCH2 subfamily.
messages: Nucleus
messages: Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways.
messages: Specifically interacts with the ligand binding domain of the thyroid receptor (TR). This interaction does not require the presence of thyroid hormone for its interaction. Interacts with proteasome subunit PSMA8; to participate in meiosis progression during spermatogenesis.

9755:OTUB1
gene id: 9755:OTUB1
uniprot id: A0A2Y9EJ61
names: Similarity
messages: Belongs to the peptidase C65 family.

9755:RPRD1A
gene id: 9755:RPRD1A
uniprot id: A0A2Y9SJS2
uniprot id: A0A2Y9SLJ6
uniprot id: A0A455AI46
uniprot id: A0A455AVZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the RNA polymerase II complex.
messages: Belongs to the UPF0400 (RTT103) family.
messages: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle.
messages: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD.
messages: Nucleus

9755:ACVR2A
gene id: 9755:ACVR2A
uniprot id: A0A2Y9ETQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

9755:IL12A
gene id: 9755:IL12A
uniprot id: A0A2Y9EXX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-6 superfamily.
messages: Heterodimer with IL12B; disulfide-linked. The heterodimer is known as interleukin IL-12.
messages: Heterodimerizes with IL12B to form the IL-12 cytokine or with EBI3/IL27B to form the IL-35 cytokine. IL-12 is primarily produced by professional antigen-presenting cells (APCs) such as B-cells and dendritic cells (DCs) as well as macrophages and granulocytes and regulates T-cell and natural killer-cell responses, induces the production of interferon-gamma (IFN-gamma), favors the differentiation of T-helper 1 (Th1) cells and is an important link between innate resistance and adaptive immunity. Mechanistically, exerts its biological effects through a receptor composed of IL12R1 and IL12R2 subunits. Binding to the receptor results in the rapid tyrosine phosphorylation of a number of cellular substrates including the JAK family kinases TYK2 and JAK2. In turn, recruited STAT4 gets phosphorylated and translocates to the nucleus where it regulates cytokine/growth factor responsive genes. As part of IL-35, plays essential roles in maintaining the immune homeostasis of the liver microenvironment and functions also as an immune-suppressive cytokine. Mediates biological events through unconventional receptors composed of IL12RB2 and gp130/IL6ST heterodimers or homodimers. Signaling requires the transcription factors STAT1 and STAT4, which form a unique heterodimer that binds to distinct DNA sites.
messages: Secreted

9755:SLC25A28
gene id: 9755:SLC25A28
uniprot id: A0A2Y9ETN5
uniprot id: A0A455ALF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9755:PIN4
gene id: 9755:PIN4
uniprot id: A0A2Y9FJ04
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family. PIN4 subfamily.

9755:LOC102983246
gene id: 9755:LOC102983246
uniprot id: A0A455B204
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

9755:LOC102984793
gene id: 9755:LOC102984793
uniprot id: A0A2Y9F9X4
names: Similarity
messages: Belongs to the BEX family.

9755:LAPTM4B
gene id: 9755:LAPTM4B
uniprot id: A0A2Y9S2L2
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

9755:DDR2
gene id: 9755:DDR2
uniprot id: A0A2Y9F2H8
uniprot id: A0A455BKU5
names: Subcellular Location Annotation
messages: Membrane

9755:GFRAL
gene id: 9755:GFRAL
uniprot id: A0A2Y9ETL3
names: Similarity
messages: Belongs to the GDNFR family.

9755:GNRH1
gene id: 9755:GNRH1
uniprot id: A0A2Y9F4J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GnRH family.
messages: Secreted
messages: Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones.

9755:GGA2
gene id: 9755:GGA2
uniprot id: A0A455C1J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

9755:FIGNL1
gene id: 9755:FIGNL1
uniprot id: A0A2Y9S0A5
uniprot id: A0A455BDU0
names: Similarity
messages: Belongs to the AAA ATPase family.

9755:AVPR1A
gene id: 9755:AVPR1A
uniprot id: A0A2Y9FIC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.

9755:MZT2B
gene id: 9755:MZT2B
uniprot id: A0A2Y9SD32
uniprot id: A0A2Y9SGX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MOZART2 family.
messages: centrosome
messages: spindle

9755:HMGN4
gene id: 9755:HMGN4
uniprot id: A0A2Y9SFX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

9755:LOC112065404
gene id: 9755:LOC112065404
uniprot id: A0A2Y9SSC4
names: Similarity
messages: Belongs to the band 7/mec-2 family.

9755:CDC42EP5
gene id: 9755:CDC42EP5
uniprot id: A0A2Y9TBV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

9755:STAM
gene id: 9755:STAM
uniprot id: A0A2Y9S461
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Early endosome membrane
messages: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes.

9755:PNLIPRP1
gene id: 9755:PNLIPRP1
uniprot id: A0A2Y9SIM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

9755:ASTE1
gene id: 9755:ASTE1
uniprot id: A0A2Y9RWQ2
uniprot id: A0A455BAJ1
uniprot id: A0A455BAJ5
names: Similarity
messages: Belongs to the asteroid family.

9755:PLPPR1
gene id: 9755:PLPPR1
uniprot id: A0A2Y9SVQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

9755:MOV10
gene id: 9755:MOV10
uniprot id: A0A2Y9F495
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
messages: P-body

9755:IRGQ
gene id: 9755:IRGQ
uniprot id: A0A2Y9TD36
uniprot id: A0A455AD83
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

9755:LOC102990390
gene id: 9755:LOC102990390
uniprot id: A0A455BTV1
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

9755:TLR1
gene id: 9755:TLR1
uniprot id: A0A2Y9S8H7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane
messages: Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides.

9755:EIF3E
gene id: 9755:EIF3E
uniprot id: A0A2Y9TCE9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit E family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with COPS3, COPS6, COPS7 (COPS7A or COPS7B), EIF4G1, EPAS1, MCM7, NCBP1, PSMC6, TRIM27 and UPF2.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. Required for nonsense-mediated mRNA decay (NMD); may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. May interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins.
messages: Cytoplasm
messages: Nucleus
messages: PML body
messages: Phosphorylated upon DNA damage, probably by ATM or ATR.

9755:LONP1
gene id: 9755:LONP1
uniprot id: A0A2Y9EVQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand-specific manner. May regulate mitochondrial DNA replication and/or gene expression using site-specific, single-stranded DNA binding to target the degradation of regulatory proteins binding to adjacent sites in mitochondrial promoters.
messages: Belongs to the peptidase S16 family.
messages: Homohexamer. Organized in a ring with a central cavity. The ATP-binding and proteolytic domains (AP-domain) form a hexameric chamber, while the N-terminal domain is arranged as a trimer of dimers. DNA and RNA binding is stimulated by substrate and inhibited by ATP binding. Interacts with TWNK and mitochondrial DNA polymerase subunit POLG.
messages: Mitochondrion matrix

9755:CCNC
gene id: 9755:CCNC
uniprot id: A0A2Y9SA09
uniprot id: A0A2Y9SD28
names: Similarity
messages: Belongs to the cyclin family.

9755:MTF2
gene id: 9755:MTF2
uniprot id: A0A2Y9EX83
uniprot id: A0A2Y9EZ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus

9755:FECH
gene id: 9755:FECH
uniprot id: A0A2Y9EFY1
uniprot id: A0A2Y9EGJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Mitochondrion inner membrane

9755:MTTP
gene id: 9755:MTTP
uniprot id: A0A2Y9F4K6
uniprot id: A0A2Y9F5E7
uniprot id: A0A455BFC3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:CCDC39
gene id: 9755:CCDC39
uniprot id: A0A2Y9SRA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC39 family.
messages: cilium axoneme

9755:BANP
gene id: 9755:BANP
uniprot id: A0A455ABX1
uniprot id: A0A455AC51
uniprot id: A0A455AC55
uniprot id: A0A455AP46
names: Similarity
messages: Belongs to the BANP/SMAR1 family.

9755:GAB2
gene id: 9755:GAB2
uniprot id: A0A2Y9TCG5
uniprot id: A0A455C911
names: Similarity
messages: Belongs to the GAB family.

9755:LOC112062648
gene id: 9755:LOC112062648
uniprot id: A0A2Y9S480
names: Subcellular Location Annotation
messages: growth cone
messages: lamellipodium

9755:HAUS1
gene id: 9755:HAUS1
uniprot id: A0A2Y9EY74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS1 family.
messages: spindle

9755:ADGRG5
gene id: 9755:ADGRG5
uniprot id: A0A2Y9SRR3
names: Subcellular Location Annotation
messages: Membrane

9755:LOC102973691
gene id: 9755:LOC102973691
uniprot id: A0A2Y9T836
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9755:NAGPA
gene id: 9755:NAGPA
uniprot id: A0A2Y9SNL7
uniprot id: A0A455C3F2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:GLB1L3
gene id: 9755:GLB1L3
uniprot id: A0A2Y9EKA2
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

9755:FXYD5
gene id: 9755:FXYD5
uniprot id: A0A2Y9EPK2
uniprot id: A0A455AF08
names: Similarity
messages: Belongs to the FXYD family.

9755:PTCH1
gene id: 9755:PTCH1
uniprot id: A0A2Y9FG26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

9755:LOC102987950
gene id: 9755:LOC102987950
uniprot id: A0A455C2Z9
names: Similarity
messages: Belongs to the PA28 family.

9755:RHAG
gene id: 9755:RHAG
uniprot id: A0A2Y9EI04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

9755:RIC8B
gene id: 9755:RIC8B
uniprot id: A0A2Y9SXW0
uniprot id: A0A2Y9T2E8
uniprot id: A0A2Y9T4J9
uniprot id: A0A455BC71
uniprot id: A0A455BEK2
uniprot id: A0A455BR44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synembryn family.
messages: Cytoplasm
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
messages: Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.

9755:PPIL6
gene id: 9755:PPIL6
uniprot id: A0A2Y9EMT4
uniprot id: A0A455BN79
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

9755:LOC102989026
gene id: 9755:LOC102989026
uniprot id: A0A455AN73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

9755:TPO
gene id: 9755:TPO
uniprot id: A0A2Y9SFY3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prostaglandin G/H synthase family.
messages: Interacts with DUOX1, DUOX2 and CYBA.
messages: Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:NCOA7
gene id: 9755:NCOA7
uniprot id: A0A2Y9FXD6
names: Similarity
messages: Belongs to the OXR1 family.

9755:F13A1
gene id: 9755:F13A1
uniprot id: A0A2Y9FJS7
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

9755:SPR
gene id: 9755:SPR
uniprot id: A0A2Y9TKA6
names: Similarity
messages: Belongs to the sepiapterin reductase family.

9755:UBE2H
gene id: 9755:UBE2H
uniprot id: A0A2Y9T2H5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9755:ACSL5
gene id: 9755:ACSL5
uniprot id: A0A2Y9FE48
uniprot id: A0A455AL64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.
messages: Endoplasmic reticulum membrane
messages: Mitochondrion outer membrane

9755:UCK1
gene id: 9755:UCK1
uniprot id: A0A2Y9F5S7
names: Similarity
messages: Belongs to the uridine kinase family.

9755:APOO
gene id: 9755:APOO
uniprot id: A0A2Y9F6F7
uniprot id: A0A455AP13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

9755:NKX2-6
gene id: 9755:NKX2-6
uniprot id: A0A2Y9EFJ4
names: Subcellular Location Annotation
messages: Nucleus

9755:DTWD2
gene id: 9755:DTWD2
uniprot id: A0A2Y9SYA0
uniprot id: A0A2Y9T0Z9
uniprot id: A0A2Y9T128
uniprot id: A0A455BJE2
names: Similarity
messages: Belongs to the TDD superfamily. DTWD2 family.

9755:OAZ1
gene id: 9755:OAZ1
uniprot id: A0A2Y9TK14
names: Similarity
messages: Belongs to the ODC antizyme family.

9755:LOC102975201
gene id: 9755:LOC102975201
uniprot id: A0A2Y9EDV7
names: Subcellular Location Annotation
messages: Nucleus

9755:YTHDF3
gene id: 9755:YTHDF3
uniprot id: A0A2Y9SVP9
uniprot id: A0A2Y9SVQ2
uniprot id: A0A2Y9T1I6
uniprot id: A0A2Y9T3P5
uniprot id: A0A455C689
uniprot id: A0A455C8T9
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

9755:CELF1
gene id: 9755:CELF1
uniprot id: A0A2Y9TJK0
uniprot id: A0A2Y9TJK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

9755:UBA7
gene id: 9755:UBA7
uniprot id: A0A2Y9F3U1
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

9755:AMER2
gene id: 9755:AMER2
uniprot id: A0A2Y9SSB5
names: Similarity
messages: Belongs to the Amer family.

9755:SLC25A20
gene id: 9755:SLC25A20
uniprot id: A0A2Y9FSX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9755:GUCY2F
gene id: 9755:GUCY2F
uniprot id: A0A2Y9ENQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane
messages: Photoreceptor outer segment membrane

9755:IFT56
gene id: 9755:IFT56
uniprot id: A0A2Y9T774
uniprot id: A0A455B959
uniprot id: A0A455B9N4
uniprot id: A0A455BC22
uniprot id: A0A455BNP7
names: Similarity
messages: Belongs to the IFT56 family.

9755:DCTN4
gene id: 9755:DCTN4
uniprot id: A0A2Y9FCA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunit 4 family.
messages: cell cortex
messages: centrosome
messages: sarcomere
messages: stress fiber

9755:PFKM
gene id: 9755:PFKM
uniprot id: A0A2Y9ELA6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9755:DEGS2
gene id: 9755:DEGS2
uniprot id: A0A2Y9EVA3
uniprot id: A0A455BU43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

9755:HOXB2
gene id: 9755:HOXB2
uniprot id: A0A2Y9EWR2
names: Subcellular Location Annotation
messages: Nucleus

9755:FGF23
gene id: 9755:FGF23
uniprot id: A0A2Y9T565
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9755:PIANP
gene id: 9755:PIANP
uniprot id: A0A2Y9EL36
names: Subcellular Location Annotation
messages: Membrane

9755:CXCR3
gene id: 9755:CXCR3
uniprot id: A0A2Y9F9M5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Homomer. Forms heteromers with ACKR4.
messages: Membrane

9755:IFNAR1
gene id: 9755:IFNAR1
uniprot id: A0A2Y9F6W6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II cytokine receptor family.
messages: Cell membrane
messages: Endosome
messages: Heterodimer with IFNAR2.
messages: Late endosome
messages: Lysosome
messages: Membrane
messages: Together with IFNAR2, forms the heterodimeric receptor for type I interferons (including interferons alpha, beta, epsilon, omega and kappa). Type I interferon binding activates the JAK-STAT signaling cascade. Can also act independently of IFNAR2: form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway.

9755:CNTF
gene id: 9755:CNTF
uniprot id: A0A2Y9F5V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNTF family.
messages: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
messages: Cytoplasm

9755:USP14
gene id: 9755:USP14
uniprot id: A0A2Y9F6S4
uniprot id: A0A455AJU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase C19 family. USP14/UBP6 subfamily.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: Homodimer (Potential). Associates with the 26S proteasome. Interacts with FANCC, CXCR4 and ERN1. Interacts with TRIM14; this interaction recruits USP14 to cleave ubiquitin chains of CGAS.

9755:ABCC11
gene id: 9755:ABCC11
uniprot id: A0A2Y9SXX4
names: Subcellular Location Annotation
messages: Membrane

9755:NEIL3
gene id: 9755:NEIL3
uniprot id: A0A2Y9FLB0
names: Similarity
messages: Belongs to the FPG family.

9755:LOC102991672
gene id: 9755:LOC102991672
uniprot id: A0A2Y9SRC5
uniprot id: A0A2Y9SXG6
uniprot id: A0A455B4A2
uniprot id: A0A455B5A2
uniprot id: A0A455B6Y2
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

9755:GPR25
gene id: 9755:GPR25
uniprot id: A0A2Y9TE46
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9755:GLIPR1L1
gene id: 9755:GLIPR1L1
uniprot id: A0A2Y9FMA4
names: Similarity
messages: Belongs to the CRISP family.

9755:PIK3R3
gene id: 9755:PIK3R3
uniprot id: A0A2Y9FTY3
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

9755:KCNA4
gene id: 9755:KCNA4
uniprot id: A0A2Y9FBW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.4/KCNA4 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: axon

9755:LOC112062521
gene id: 9755:LOC112062521
uniprot id: A0A2Y9S2U9
uniprot id: A0A2Y9S9E7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that hydrolyzes the non-canonical purine (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.

9755:C8B
gene id: 9755:C8B
uniprot id: A0A2Y9ELN5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9755:TNC
gene id: 9755:TNC
uniprot id: A0A2Y9SUT5
uniprot id: A0A455BKY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family.
messages: extracellular matrix

9755:DCTD
gene id: 9755:DCTD
uniprot id: A0A2Y9S5W7
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

9755:AURKA
gene id: 9755:AURKA
uniprot id: A0A2Y9ELJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
messages: centrosome

9755:STRA6
gene id: 9755:STRA6
uniprot id: A0A2Y9T6P9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9755:CLIC2
gene id: 9755:CLIC2
uniprot id: A0A2Y9F7K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Membrane

9755:UBA3
gene id: 9755:UBA3
uniprot id: A0A2Y9SNP2
uniprot id: A0A2Y9SR69
uniprot id: A0A2Y9STV7
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
messages: Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.

9755:TRNT1
gene id: 9755:TRNT1
uniprot id: A0A2Y9SLN3
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

9755:EXOC2
gene id: 9755:EXOC2
uniprot id: A0A2Y9EFH2
uniprot id: A0A455AFP2
uniprot id: A0A455AHK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SEC5 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: Component of the exocyst complex.