9739:DSE
gene id: 9739:DSE
uniprot id: A0A2U4AW44
uniprot id: A0A2U4AW49
uniprot id: A0A6J3S8Z1
uniprot id: A0A6J3S9N4
uniprot id: A0A6J3SAI8
uniprot id: A0A6J3SAK2
names: Similarity
messages: Belongs to the dermatan-sulfate isomerase family.

9739:STRADA
gene id: 9739:STRADA
uniprot id: A0A6J3QJV7
uniprot id: A0A6J3QJZ7
uniprot id: A0A6J3QKI1
uniprot id: A0A6J3QKK8
uniprot id: A0A6J3QKL4
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.

9739:ZMYND10
gene id: 9739:ZMYND10
uniprot id: A0A6J3S230
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the ZMYND10 family.
messages: Dynein axonemal particle
messages: Plays a role in axonemal structure organization and motility. Involved in axonemal pre-assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility. May act by indirectly regulating transcription of dynein proteins.
messages: centriolar satellite

9739:TRAPPC1
gene id: 9739:TRAPPC1
uniprot id: A0A6J3QQ89
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

9739:TTC21B
gene id: 9739:TTC21B
uniprot id: A0A2U4ACI5
uniprot id: A0A6J3RN58
names: Similarity
messages: Belongs to the TTC21 family.

9739:MTMR2
gene id: 9739:MTMR2
uniprot id: A0A2U3V618
uniprot id: A0A2U4AEW9
uniprot id: A0A6J3RTP2
uniprot id: A0A6J3RU43
uniprot id: A0A6J3RU73
uniprot id: A0A6J3RUF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

9739:STPG4
gene id: 9739:STPG4
uniprot id: A0A2U4BXU5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9739:CPD
gene id: 9739:CPD
uniprot id: A0A2U4ANH7
uniprot id: A0A2U4ANH8
names: Similarity
messages: Belongs to the peptidase M14 family.

9739:CCNB2
gene id: 9739:CCNB2
uniprot id: A0A2U4CBV9
names: Similarity
messages: Belongs to the cyclin family.

9739:CD70
gene id: 9739:CD70
uniprot id: A0A6J3R9E2
uniprot id: A0A6J3RB62
names: Similarity
messages: Belongs to the tumor necrosis factor family.

9739:TRAPPC11
gene id: 9739:TRAPPC11
uniprot id: A0A2U4A7T3
uniprot id: A0A6J3QQD6
uniprot id: A0A6J3QR07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPPC11 family.
messages: Involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage.
messages: cis-Golgi network

9739:DMRTB1
gene id: 9739:DMRTB1
uniprot id: A0A2U3V7R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

9739:HAT1
gene id: 9739:HAT1
uniprot id: A0A2U3V404
uniprot id: A0A2U4ACE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAT1 family.
messages: Catalytic subunit of the type B histone acetyltransferase (HAT) complex, composed of RBBP7 and HAT1. Interacts with histones H4 and H2A.
messages: Histone acetyltransferase that plays a role in different biological processes including cell cycle progression, glucose metabolism, histone production or DNA damage repair. Coordinates histone production and acetylation via H4 promoter binding. Acetylates histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, histone H2A at 'Lys-5' (H2AK5ac).

9739:MRPS27
gene id: 9739:MRPS27
uniprot id: A0A2U4AWT7
uniprot id: A0A2U4AWU9
uniprot id: A0A2U4AWW5
uniprot id: A0A2U4AXB8
names: Subcellular Location Annotation
messages: Mitochondrion

9739:DOCK6
gene id: 9739:DOCK6
uniprot id: A0A6J3R5S3
uniprot id: A0A6J3R5S8
uniprot id: A0A6J3R5T2
uniprot id: A0A6J3R5V7
uniprot id: A0A6J3R5W1
uniprot id: A0A6J3R6E0
uniprot id: A0A6J3R6E6
uniprot id: A0A6J3R6Q8
uniprot id: A0A6J3R6R3
uniprot id: A0A6J3R6S0
uniprot id: A0A6J3R8H6
uniprot id: A0A6J3R8I2
uniprot id: A0A6J3R8I7
names: Similarity
messages: Belongs to the DOCK family.

9739:DYNLL2
gene id: 9739:DYNLL2
uniprot id: A0A6J3QLA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

9739:GCNT1
gene id: 9739:GCNT1
uniprot id: A0A2U4BAG9
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

9739:LOC101320092
gene id: 9739:LOC101320092
uniprot id: A0A2U4B0F7
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.

9739:PGAP1
gene id: 9739:PGAP1
uniprot id: A0A2U4BNI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI inositol-deacylase family.
messages: Endoplasmic reticulum membrane
messages: Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

9739:WASHC1
gene id: 9739:WASHC1
uniprot id: A0A6J3S7S7
uniprot id: A0A6J3S841
uniprot id: A0A6J3S8D5
uniprot id: A0A6J3S8D9
uniprot id: A0A6J3S9E4
uniprot id: A0A6J3S9J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WASH1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Recycling endosome membrane

9739:CCKAR
gene id: 9739:CCKAR
uniprot id: A0A2U4AT12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

9739:SLC39A10
gene id: 9739:SLC39A10
uniprot id: A0A2U4BNL3
names: Subcellular Location Annotation
messages: Membrane

9739:SEMA5A
gene id: 9739:SEMA5A
uniprot id: A0A2U4CMF7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:SLC7A11
gene id: 9739:SLC7A11
uniprot id: A0A2U4ARB8
uniprot id: A0A2U4ARR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Cell membrane
messages: Membrane

9739:MED31
gene id: 9739:MED31
uniprot id: A0A2U3UYJ5
uniprot id: A0A2U4AN61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 31 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

9739:C2
gene id: 9739:C2
uniprot id: A0A6J3RZA8
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9739:EFNA5
gene id: 9739:EFNA5
uniprot id: A0A2U4BT02
uniprot id: A0A2U4BT12
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:DRGX
gene id: 9739:DRGX
uniprot id: A0A6J3Q8A2
names: Subcellular Location Annotation
messages: Nucleus

9739:LOC101319307
gene id: 9739:LOC101319307
uniprot id: A0A6J3Q6F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

9739:LOC109552633
gene id: 9739:LOC109552633
uniprot id: A0A6J3Q112
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

9739:APOLD1
gene id: 9739:APOLD1
uniprot id: A0A2U4BIQ3
names: Similarity
messages: Belongs to the apolipoprotein L family.

9739:TM4SF18
gene id: 9739:TM4SF18
uniprot id: A0A2U4B9Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

9739:C17H8orf33
gene id: 9739:C17H8orf33
uniprot id: A0A6J3Q964
names: Similarity
messages: Belongs to the UPF0488 family.

9739:LOC117311566
gene id: 9739:LOC117311566
uniprot id: A0A2U3V409
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

9739:TXLNA
gene id: 9739:TXLNA
uniprot id: A0A2U4BKQ2
names: Similarity
messages: Belongs to the taxilin family.

9739:BEST3
gene id: 9739:BEST3
uniprot id: A0A2U3ZZQ6
uniprot id: A0A6J3S5M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.
messages: Cell membrane
messages: Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
messages: Membrane

9739:FAM133B
gene id: 9739:FAM133B
uniprot id: A0A2U3UYU8
uniprot id: A0A2U4APK6
uniprot id: A0A6J3RWM3
uniprot id: A0A6J3RWP5
names: Similarity
messages: Belongs to the FAM133 family.

9739:DNAAF1
gene id: 9739:DNAAF1
uniprot id: A0A2U4BUN5
uniprot id: A0A6J3QBK2
uniprot id: A0A6J3QC39
uniprot id: A0A6J3QCA3
uniprot id: A0A6J3QCI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNAAF1 family.
messages: Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli.
messages: cilium

9739:GRM3
gene id: 9739:GRM3
uniprot id: A0A2U4B1M4
uniprot id: A0A2U4B1P1
uniprot id: A0A2U4B216
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
messages: Interacts with TAMALIN.
messages: Membrane

9739:TXK
gene id: 9739:TXK
uniprot id: A0A2U3V2J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

9739:TMEM233
gene id: 9739:TMEM233
uniprot id: A0A6J3PVA7
names: Similarity
messages: Belongs to the CD225/Dispanin family.

9739:LOX
gene id: 9739:LOX
uniprot id: A0A6J3R2M5
uniprot id: A0A6J3R2R7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

9739:SCD5
gene id: 9739:SCD5
uniprot id: A0A6J3RER8
uniprot id: A0A6J3RGH8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

9739:ASTE1
gene id: 9739:ASTE1
uniprot id: A0A2U4B9R1
uniprot id: A0A2U4B9R5
uniprot id: A0A2U4B9U3
names: Similarity
messages: Belongs to the asteroid family.

9739:MRPL3
gene id: 9739:MRPL3
uniprot id: A0A2U3V3F3
uniprot id: A0A2U4B9T3
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

9739:SPNS1
gene id: 9739:SPNS1
uniprot id: A0A6J3PYW7
uniprot id: A0A6J3PZ32
uniprot id: A0A6J3PZE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

9739:POU4F1
gene id: 9739:POU4F1
uniprot id: A0A6J3QB31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

9739:EDA2R
gene id: 9739:EDA2R
uniprot id: A0A2U4CGU0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:SAP130
gene id: 9739:SAP130
uniprot id: A0A2U4B2D7
uniprot id: A0A2U4B2D8
uniprot id: A0A2U4B2F9
uniprot id: A0A2U4B2I1
uniprot id: A0A2U4B2I8
uniprot id: A0A2U4B2T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAP130 family.
messages: Nucleus

9739:EIF3K
gene id: 9739:EIF3K
uniprot id: A0A6J3QFV3
uniprot id: A0A6J3QGI4
uniprot id: A0A6J3QGJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit K family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with CCND3, but not with CCND1 and CCND2.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm
messages: Nucleus

9739:BMP2
gene id: 9739:BMP2
uniprot id: A0A2U4BV21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

9739:DGCR2
gene id: 9739:DGCR2
uniprot id: A0A6J3PT02
uniprot id: A0A6J3PT68
uniprot id: A0A6J3PTK7
uniprot id: A0A6J3PTL1
uniprot id: A0A6J3PTN0
uniprot id: A0A6J3PU53
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:AGAP3
gene id: 9739:AGAP3
uniprot id: A0A6J3RXR9
uniprot id: A0A6J3RXS3
uniprot id: A0A6J3RXS5
uniprot id: A0A6J3RXW9
uniprot id: A0A6J3RXX7
uniprot id: A0A6J3RYN1
names: Similarity
messages: Belongs to the centaurin gamma-like family.

9739:LOC101322445
gene id: 9739:LOC101322445
uniprot id: A0A2U4BHT9
names: Similarity
messages: Belongs to the cytochrome b5 family.

9739:AREL1
gene id: 9739:AREL1
uniprot id: A0A6J3QW62
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:CPN1
gene id: 9739:CPN1
uniprot id: A0A2U4BQ81
uniprot id: A0A2U4BQJ9
names: Similarity
messages: Belongs to the peptidase M14 family.

9739:NECTIN3
gene id: 9739:NECTIN3
uniprot id: A0A6J3RA43
uniprot id: A0A6J3RB68
names: Similarity
messages: Belongs to the nectin family.

9739:EDNRB
gene id: 9739:EDNRB
uniprot id: A0A2U3V985
uniprot id: A0A2U4A6W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9739:LOC101333630
gene id: 9739:LOC101333630
uniprot id: A0A2U3UZS7
names: Similarity
messages: Belongs to the DNAJC25 family.

9739:PITHD1
gene id: 9739:PITHD1
uniprot id: A0A2U3V4G0
uniprot id: A0A6J3Q4N3
names: Similarity
messages: Belongs to the PITHD1 family.

9739:WDR24
gene id: 9739:WDR24
uniprot id: A0A2U3UZY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR24 family.
messages: Lysosome membrane

9739:MRPL42
gene id: 9739:MRPL42
uniprot id: A0A2U4CS19
uniprot id: A0A2U4CS93
uniprot id: A0A6J3S5H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL42 family.
messages: Mitochondrion

9739:GPC3
gene id: 9739:GPC3
uniprot id: A0A2U4A0W5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

9739:DLL1
gene id: 9739:DLL1
uniprot id: A0A6J3PQX0
uniprot id: A0A6J3PRE3
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

9739:DHX58
gene id: 9739:DHX58
uniprot id: A0A6J3QQA6
uniprot id: A0A6J3QQG5
uniprot id: A0A6J3QQU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

9739:PIGZ
gene id: 9739:PIGZ
uniprot id: A0A2U3V5E0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:CDH11
gene id: 9739:CDH11
uniprot id: A0A2U4BDW2
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

9739:JAK1
gene id: 9739:JAK1
uniprot id: A0A2U4A1Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system

9739:LOC117312190
gene id: 9739:LOC117312190
uniprot id: A0A6J3RBV8
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

9739:CCNDBP1
gene id: 9739:CCNDBP1
uniprot id: A0A6J3QZ48
names: Similarity
names: Subunit
messages: Belongs to the CCNDBP1 family.
messages: Interacts with CCND1 and GRAP2. May also interact with COPS5, RPLP0, SIRT6, SYF2 and TCF3.

9739:RAPGEF2
gene id: 9739:RAPGEF2
uniprot id: A0A2U4ALU5
uniprot id: A0A2U4ALU9
uniprot id: A0A2U4ALV1
uniprot id: A0A6J3REV4
uniprot id: A0A6J3REX7
uniprot id: A0A6J3RFD5
uniprot id: A0A6J3RFP1
names: Similarity
messages: Belongs to the RAPGEF2 family.

9739:TIMM8B
gene id: 9739:TIMM8B
uniprot id: A0A2U3V147
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

9739:TRHDE
gene id: 9739:TRHDE
uniprot id: A0A2U4A013
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Membrane

9739:DNAJC18
gene id: 9739:DNAJC18
uniprot id: A0A2U3V4W2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:HNRNPR
gene id: 9739:HNRNPR
uniprot id: A0A6J3Q4Y1
uniprot id: A0A6J3Q505
uniprot id: A0A6J3Q519
uniprot id: A0A6J3Q583
uniprot id: A0A6J3Q5G6
uniprot id: A0A6J3Q5I0
uniprot id: A0A6J3Q5R0
names: Subcellular Location Annotation
messages: Cytoplasm

9739:SLC24A4
gene id: 9739:SLC24A4
uniprot id: A0A6J3QWQ4
uniprot id: A0A6J3QXN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

9739:SLC6A4
gene id: 9739:SLC6A4
uniprot id: A0A2U4ANI2
uniprot id: A0A2U4ANW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A4 subfamily.
messages: Cell membrane
messages: Endomembrane system
messages: Endosome membrane
messages: Membrane
messages: Synapse
messages: focal adhesion
messages: neuron projection

9739:LOC117308966
gene id: 9739:LOC117308966
uniprot id: A0A6J3QCX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lambda interferon family.
messages: Secreted

9739:AMOT
gene id: 9739:AMOT
uniprot id: A0A2U4CIF8
names: Similarity
messages: Belongs to the angiomotin family.

9739:LOC101320296
gene id: 9739:LOC101320296
uniprot id: A0A6J3R4P2
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

9739:ADCY8
gene id: 9739:ADCY8
uniprot id: A0A2U4B2P8
uniprot id: A0A2U4B351
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

9739:LOC101315930
gene id: 9739:LOC101315930
uniprot id: A0A2U4CEV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9739:GRB14
gene id: 9739:GRB14
uniprot id: A0A2U4AB59
uniprot id: A0A2U4AB64
uniprot id: A0A2U4AB98
uniprot id: A0A2U4ABA2
uniprot id: A0A2U4ABB1
uniprot id: A0A2U4ABB7
uniprot id: A0A2U4ABC2
uniprot id: A0A2U4ABH9
uniprot id: A0A2U4ABI2
uniprot id: A0A2U4ABI9
uniprot id: A0A2U4ABU0
uniprot id: A0A2U4ABU6
uniprot id: A0A6J3RNN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

9739:PLPBP
gene id: 9739:PLPBP
uniprot id: A0A2U3V3F0
uniprot id: A0A2U4A7Z3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.

9739:CALCRL
gene id: 9739:CALCRL
uniprot id: A0A2U4B211
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Heterodimer of CALCRL and RAMP1, RAMP2 or RAMP3.
messages: Membrane
messages: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

9739:SEPTIN14
gene id: 9739:SEPTIN14
uniprot id: A0A2U3V7N6
uniprot id: A0A2U4A8G6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

9739:SF3A2
gene id: 9739:SF3A2
uniprot id: A0A6J3R7J3
names: Similarity
messages: Belongs to the SF3A2 family.

9739:PARVB
gene id: 9739:PARVB
uniprot id: A0A6J3S4E6
uniprot id: A0A6J3S5C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parvin family.
messages: Cell membrane

9739:EFNA3
gene id: 9739:EFNA3
uniprot id: A0A6J3RG65
uniprot id: A0A6J3RG71
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:SAMHD1
gene id: 9739:SAMHD1
uniprot id: A0A2U4CLM5
uniprot id: A0A2U4CLM6
uniprot id: A0A2U4CLN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAMHD1 family.
messages: Chromosome

9739:PBX3
gene id: 9739:PBX3
uniprot id: A0A2U4CH73
uniprot id: A0A2U4CH76
uniprot id: A0A2U4CH79
uniprot id: A0A2U4CH89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

9739:SLC7A4
gene id: 9739:SLC7A4
uniprot id: A0A2U3V9S7
uniprot id: A0A2U4ALQ6
names: Subcellular Location Annotation
messages: Membrane

9739:FBXO32
gene id: 9739:FBXO32
uniprot id: A0A2U3V573
names: Subcellular Location Annotation
messages: Nucleus

9739:GTF3C5
gene id: 9739:GTF3C5
uniprot id: A0A6J3RJA0
uniprot id: A0A6J3RJK3
uniprot id: A0A6J3RLC5
names: Subcellular Location Annotation
messages: Nucleus

9739:THTPA
gene id: 9739:THTPA
uniprot id: A0A2U4AFH2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Hydrolase highly specific for thiamine triphosphate (ThTP).
messages: Monomer.

9739:NIPAL3
gene id: 9739:NIPAL3
uniprot id: A0A2U4BLF5
uniprot id: A0A2U4BLG0
uniprot id: A0A2U4BLG1
uniprot id: A0A2U4BLG3
uniprot id: A0A2U4BLG6
uniprot id: A0A2U4BLG8
uniprot id: A0A2U4BLK2
uniprot id: A0A2U4BLK7
uniprot id: A0A6J3Q445
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

9739:GHSR
gene id: 9739:GHSR
uniprot id: A0A2U3V912
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9739:KCNH6
gene id: 9739:KCNH6
uniprot id: A0A6J3QMJ3
uniprot id: A0A6J3QMZ0
uniprot id: A0A6J3QNJ6
names: Subcellular Location Annotation
messages: Membrane

9739:LOC101335459
gene id: 9739:LOC101335459
uniprot id: A0A2U3V128
uniprot id: A0A2U4C4D8
uniprot id: A0A2U4C4G4
uniprot id: A0A2U4C4K3
names: Subcellular Location Annotation
messages: Membrane

9739:SRP19
gene id: 9739:SRP19
uniprot id: A0A2U3V4F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP19 family.
messages: Cytoplasm

9739:ZAN
gene id: 9739:ZAN
uniprot id: A0A6J3Q1R9
uniprot id: A0A6J3Q228
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:LDLRAD1
gene id: 9739:LDLRAD1
uniprot id: A0A6J3R3J9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:LOC117313727
gene id: 9739:LOC117313727
uniprot id: A0A6J3RZ35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H3 family.
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus

9739:LOC117312663
gene id: 9739:LOC117312663
uniprot id: A0A6J3RID9
names: Similarity
messages: Belongs to the BRINP family.

9739:TCN1
gene id: 9739:TCN1
uniprot id: A0A2U4CF68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic cobalamin transport proteins family.
messages: Secreted

9739:ARMCX1
gene id: 9739:ARMCX1
uniprot id: A0A2U4B3T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eutherian X-chromosome-specific Armcx family.
messages: Membrane

9739:ATG9B
gene id: 9739:ATG9B
uniprot id: A0A6J3RVP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

9739:LOC101333684
gene id: 9739:LOC101333684
uniprot id: A0A2U4BY65
names: Subcellular Location Annotation
messages: Membrane

9739:PLAC8L1
gene id: 9739:PLAC8L1
uniprot id: A0A2U4AGV2
names: Similarity
messages: Belongs to the cornifelin family.

9739:MTTP
gene id: 9739:MTTP
uniprot id: A0A2U4AM27
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:LOC117307495
gene id: 9739:LOC117307495
uniprot id: A0A2U4CA67
names: Subcellular Location Annotation
messages: Nucleus

9739:RGR
gene id: 9739:RGR
uniprot id: A0A2U3V4D0
uniprot id: A0A2U4AKD0
uniprot id: A0A6J3Q7I3
names: Subcellular Location Annotation
messages: Membrane

9739:DGAT1
gene id: 9739:DGAT1
uniprot id: A0A6J3Q974
uniprot id: A0A6J3Q978
uniprot id: A0A6J3Q9Y8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Homodimer or homotetramer; both forms have similar enzymatic activities.
messages: Membrane

9739:LOC109549824
gene id: 9739:LOC109549824
uniprot id: A0A6J3RKM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ran family.
messages: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.
messages: Nucleus

9739:LOC101328364
gene id: 9739:LOC101328364
uniprot id: A0A2U3V217
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9739:LOC101318303
gene id: 9739:LOC101318303
uniprot id: A0A6J3RPG3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

9739:SLC22A2
gene id: 9739:SLC22A2
uniprot id: A0A2U3V8I3
uniprot id: A0A6J3S9Y4
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

9739:NMNAT2
gene id: 9739:NMNAT2
uniprot id: A0A2U4CQX7
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

9739:OTULIN
gene id: 9739:OTULIN
uniprot id: A0A2U3V763
uniprot id: A0A2U4CME2
uniprot id: A0A2U4CME4
uniprot id: A0A2U4CMK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C65 family. Otulin subfamily.
messages: Cytoplasm

9739:NDUFV3
gene id: 9739:NDUFV3
uniprot id: A0A2U3V0N6
uniprot id: A0A2U4AC54
uniprot id: A0A2U4ACS2
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. May be the terminally assembled subunit of Complex I.
messages: Belongs to the complex I NDUFV3 subunit family.
messages: Complex I is composed of 45 different subunits. This is a component of the flavoprotein-sulfur (FP) fragment of the enzyme.

9739:MRPL49
gene id: 9739:MRPL49
uniprot id: A0A6J3RQP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL49 family.
messages: Mitochondrion

9739:FGF14
gene id: 9739:FGF14
uniprot id: A0A2U4A7B2
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9739:LOC101335630
gene id: 9739:LOC101335630
uniprot id: A0A6J3RWY8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: clathrin-coated vesicle membrane

9739:SCRN1
gene id: 9739:SCRN1
uniprot id: A0A2U4ALA3
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

9739:MTURN
gene id: 9739:MTURN
uniprot id: A0A2U3V3B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTURN family.
messages: Cytoplasm

9739:FXYD6
gene id: 9739:FXYD6
uniprot id: A0A2U4BW62
uniprot id: A0A6J3RTX0
names: Similarity
messages: Belongs to the FXYD family.

9739:WDR82
gene id: 9739:WDR82
uniprot id: A0A2U3V4Z3
uniprot id: A0A2U4CCQ8
uniprot id: A0A2U4CCR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SWD2 family.
messages: Nucleus

9739:CD164L2
gene id: 9739:CD164L2
uniprot id: A0A6J3Q0T6
uniprot id: A0A6J3Q0U2
uniprot id: A0A6J3Q0V9
uniprot id: A0A6J3Q122
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD164 family.
messages: Membrane

9739:LOC101327612
gene id: 9739:LOC101327612
uniprot id: A0A6J3RES2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

9739:LOC101325805
gene id: 9739:LOC101325805
uniprot id: A0A6J3RB48
names: Similarity
messages: Belongs to the cytochrome P450 family.

9739:BTC
gene id: 9739:BTC
uniprot id: A0A2U3V975
uniprot id: A0A2U4B4Y1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:MICAL1
gene id: 9739:MICAL1
uniprot id: A0A6J3S8V8
uniprot id: A0A6J3S8W2
uniprot id: A0A6J3S962
uniprot id: A0A6J3S971
uniprot id: A0A6J3S9K2
uniprot id: A0A6J3SAG2
uniprot id: A0A6J3SAH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Cytoplasm

9739:SNTB2
gene id: 9739:SNTB2
uniprot id: A0A2U4BD89
uniprot id: A0A2U4BDB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

9739:ELF1
gene id: 9739:ELF1
uniprot id: A0A2U4BFM3
uniprot id: A0A2U4BFN1
uniprot id: A0A2U4BG19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9739:TMPRSS11E
gene id: 9739:TMPRSS11E
uniprot id: A0A2U4ARR0
uniprot id: A0A2U4ARR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Membrane

9739:UBA52
gene id: 9739:UBA52
uniprot id: A0A2U3V125
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Component of the 60S subunit of the ribosome. Ribosomal protein L40 is essential for translation of a subset of cellular transcripts, and especially for cap-dependent translation of vesicular stomatitis virus mRNAs.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Nucleus
messages: Part of the 60S ribosomal subunit. Interacts with UBQLN1 (via UBA domain).

9739:RAD1
gene id: 9739:RAD1
uniprot id: A0A2U3V6U3
uniprot id: A0A2U4AXN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad1 family.
messages: Nucleus

9739:IMMT
gene id: 9739:IMMT
uniprot id: A0A2U4BX34
uniprot id: A0A2U4BX36
uniprot id: A0A2U4BX37
uniprot id: A0A2U4BX86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic60 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

9739:VARS2
gene id: 9739:VARS2
uniprot id: A0A6J3RZ20
uniprot id: A0A6J3RZ46
uniprot id: A0A6J3RZ59
uniprot id: A0A6J3RZD0
uniprot id: A0A6J3S017
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9739:MID1
gene id: 9739:MID1
uniprot id: A0A2U4AT19
uniprot id: A0A2U4AT42
uniprot id: A0A2U4ATI3
uniprot id: A0A6J3QU89
names: Subcellular Location Annotation
messages: cytoskeleton

9739:PUS3
gene id: 9739:PUS3
uniprot id: A0A2U3V493
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

9739:ZCCHC4
gene id: 9739:ZCCHC4
uniprot id: A0A2U4ASK2
uniprot id: A0A2U4ASK3
uniprot id: A0A2U4ASM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZCCHC4 family.
messages: Cytoplasm
messages: nucleolus

9739:S100A11
gene id: 9739:S100A11
uniprot id: A0A2U3V6R1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the S-100 family.
messages: Facilitates the differentiation and the cornification of keratinocytes.
messages: Homodimer; disulfide-linked.

9739:NT5C3A
gene id: 9739:NT5C3A
uniprot id: A0A2U3V1M1
uniprot id: A0A2U4AL11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

9739:RPS18
gene id: 9739:RPS18
uniprot id: A0A2U3V3Z7
uniprot id: A0A6J3S0H7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Component of the small ribosomal subunit.

9739:LOC101320088
gene id: 9739:LOC101320088
uniprot id: A0A2U4BNS2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9739:RPS26
gene id: 9739:RPS26
uniprot id: A0A2U3V215
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

9739:AZIN1
gene id: 9739:AZIN1
uniprot id: A0A2U3UYE8
uniprot id: A0A2U4AHW3
uniprot id: A0A2U4AI53
uniprot id: A0A6J3Q7X4
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

9739:DSG1
gene id: 9739:DSG1
uniprot id: A0A2U4AYH0
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

9739:DCLK2
gene id: 9739:DCLK2
uniprot id: A0A6J3REK3
uniprot id: A0A6J3REK8
uniprot id: A0A6J3REM8
uniprot id: A0A6J3RF41
uniprot id: A0A6J3RF46
uniprot id: A0A6J3RFE4
uniprot id: A0A6J3RGW7
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

9739:LOC117307519
gene id: 9739:LOC117307519
uniprot id: A0A6J3QSA1
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.

9739:SLC16A1
gene id: 9739:SLC16A1
uniprot id: A0A6J3RSI7
uniprot id: A0A6J3RSL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

9739:LOC101321068
gene id: 9739:LOC101321068
uniprot id: A0A6J3S839
names: Function
names: Subunit
messages: Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine.
messages: Monomer.

9739:ELOVL1
gene id: 9739:ELOVL1
uniprot id: A0A6J3PR74
uniprot id: A0A6J3PRQ5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ELO family. ELOVL1 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs.
messages: Endoplasmic reticulum membrane
messages: Interacts with LASS2, TECR and HSD17B12.
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

9739:DCLK1
gene id: 9739:DCLK1
uniprot id: A0A6J3QB25
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

9739:DGLUCY
gene id: 9739:DGLUCY
uniprot id: A0A6J3QS62
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

9739:SSR2
gene id: 9739:SSR2
uniprot id: A0A6J3RF95
uniprot id: A0A6J3RFA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-beta family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

9739:CMTM3
gene id: 9739:CMTM3
uniprot id: A0A2U4BDJ5
names: Subcellular Location Annotation
messages: Membrane

9739:FAM183A
gene id: 9739:FAM183A
uniprot id: A0A2U3VA58
names: Similarity
messages: Belongs to the CFAP144 family.

9739:POLM
gene id: 9739:POLM
uniprot id: A0A2U4BMR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ).
messages: Nucleus

9739:LOC101316121
gene id: 9739:LOC101316121
uniprot id: A0A2U3V5Z5
names: Similarity
messages: Belongs to the PRORSD1 family.

9739:MCTP1
gene id: 9739:MCTP1
uniprot id: A0A2U4AW94
uniprot id: A0A2U4AWR9
uniprot id: A0A6J3R2F2
uniprot id: A0A6J3R2I8
uniprot id: A0A6J3R2W7
names: Subcellular Location Annotation
messages: Membrane

9739:FERMT1
gene id: 9739:FERMT1
uniprot id: A0A2U4BUW4
uniprot id: A0A2U4BUW5
names: Similarity
messages: Belongs to the kindlin family.

9739:XRCC1
gene id: 9739:XRCC1
uniprot id: A0A6J3QGK6
uniprot id: A0A6J3QGM9
uniprot id: A0A6J3QHA2
uniprot id: A0A6J3QHQ6
names: Subcellular Location Annotation
messages: Nucleus

9739:LOC117308146
gene id: 9739:LOC117308146
uniprot id: A0A6J3Q102
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane

9739:COMTD1
gene id: 9739:COMTD1
uniprot id: A0A2U3V2N3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

9739:FRZB
gene id: 9739:FRZB
uniprot id: A0A2U3V8T5
names: Caution
names: Function
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development.

9739:RPL37A
gene id: 9739:RPL37A
uniprot id: A0A2U4BMS4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

9739:DNAAF4
gene id: 9739:DNAAF4
uniprot id: A0A2U4CA32
uniprot id: A0A2U4CAC2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Dynein axonemal particle
messages: neuron projection

9739:RPL12
gene id: 9739:RPL12
uniprot id: A0A6J3RKF5
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Binds directly to 26S ribosomal RNA.

9739:ITGAV
gene id: 9739:ITGAV
uniprot id: A0A2U3V2K6
uniprot id: A0A2U4B1M0
uniprot id: A0A2U4B1Q1
uniprot id: A0A6J3RM27
uniprot id: A0A6J3RMV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9739:LOC101326964
gene id: 9739:LOC101326964
uniprot id: A0A2U4CDJ8
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

9739:GABRB3
gene id: 9739:GABRB3
uniprot id: A0A6J3R197
uniprot id: A0A6J3R1I9
uniprot id: A0A6J3R227
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9739:APEX1
gene id: 9739:APEX1
uniprot id: A0A2U4BCE8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Cytoplasm
messages: Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
messages: Mitochondrion
messages: Nucleus
messages: Probably binds two magnesium or manganese ions per subunit.

9739:NOVA1
gene id: 9739:NOVA1
uniprot id: A0A6J3QY62
uniprot id: A0A6J3QZ26
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with PTBP2; the interaction is direct.
messages: Nucleus

9739:P2RX7
gene id: 9739:P2RX7
uniprot id: A0A2U4CKT4
uniprot id: A0A2U4CKT7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P2X receptor family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

9739:DHDDS
gene id: 9739:DHDDS
uniprot id: A0A2U4BL69
uniprot id: A0A2U4BL83
uniprot id: A0A2U4BLB9
names: Similarity
messages: Belongs to the UPP synthase family.

9739:LSM7
gene id: 9739:LSM7
uniprot id: A0A6J3R7K5
uniprot id: A0A6J3R803
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

9739:SSBP3
gene id: 9739:SSBP3
uniprot id: A0A6J3S583
uniprot id: A0A6J3S594
uniprot id: A0A6J3S5E4
uniprot id: A0A6J3S5F0
uniprot id: A0A6J3S5F9
uniprot id: A0A6J3S5G9
uniprot id: A0A6J3S5J8
uniprot id: A0A6J3S5L9
uniprot id: A0A6J3S6F6
uniprot id: A0A6J3S6G7
uniprot id: A0A6J3S6I5
names: Subcellular Location Annotation
messages: Nucleus

9739:LOC101324526
gene id: 9739:LOC101324526
uniprot id: A0A6J3RF43
names: Subcellular Location Annotation
messages: Cytoplasm
messages: nucleoplasm
messages: podosome

9739:DPYSL5
gene id: 9739:DPYSL5
uniprot id: A0A2U4C0H1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

9739:CPO
gene id: 9739:CPO
uniprot id: A0A6J3RNZ1
names: Similarity
messages: Belongs to the peptidase M14 family.

9739:LOC117310292
gene id: 9739:LOC117310292
uniprot id: A0A6J3QT12
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9739:LOC101323693
gene id: 9739:LOC101323693
uniprot id: A0A6J3RNV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

9739:C1H1orf52
gene id: 9739:C1H1orf52
uniprot id: A0A2U4A3S7
names: Similarity
messages: Belongs to the UPF0690 family.

9739:SLIT2
gene id: 9739:SLIT2
uniprot id: A0A2U4ASN8
uniprot id: A0A2U4ASP4
uniprot id: A0A2U4ASR5
uniprot id: A0A2U4AT58
uniprot id: A0A6J3RDC9
uniprot id: A0A6J3RE67
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9739:LOC117311151
gene id: 9739:LOC117311151
uniprot id: A0A6J3R0H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9739:LOC101328460
gene id: 9739:LOC101328460
uniprot id: A0A2U4C5W1
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.

9739:LOC101331234
gene id: 9739:LOC101331234
uniprot id: A0A6J3RJC2
uniprot id: A0A6J3RJM4
uniprot id: A0A6J3RKI0
uniprot id: A0A6J3RLE5
names: Similarity
messages: Belongs to the ficolin lectin family.

9739:EEF2K
gene id: 9739:EEF2K
uniprot id: A0A6J3Q1R4
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. Alpha-type protein kinase family.
messages: Monomer or homodimer.
messages: Undergoes calcium/calmodulin-dependent intramolecular autophosphorylation, and this results in it becoming partially calcium/calmodulin-independent.

9739:LOC101340076
gene id: 9739:LOC101340076
uniprot id: A0A6J3R733
uniprot id: A0A6J3R743
uniprot id: A0A6J3R745
uniprot id: A0A6J3R7I2
uniprot id: A0A6J3R7K6
uniprot id: A0A6J3R7M1
uniprot id: A0A6J3R808
uniprot id: A0A6J3R9V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC16 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.
messages: SEC16A and SEC16B are each present in multiple copies in a heteromeric complex.

9739:MRTO4
gene id: 9739:MRTO4
uniprot id: A0A6J3Q7D6
uniprot id: A0A6J3Q7R6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the pre-60S ribosomal particle.
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
messages: Cytoplasm
messages: nucleolus

9739:TUBGCP4
gene id: 9739:TUBGCP4
uniprot id: A0A2U4BCQ6
uniprot id: A0A6J3QZ63
uniprot id: A0A6J3R051
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

9739:LOC101321204
gene id: 9739:LOC101321204
uniprot id: A0A2U3V213
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9739:CANX
gene id: 9739:CANX
uniprot id: A0A2U3UZZ2
names: Similarity
messages: Belongs to the calreticulin family.

9739:PLK3
gene id: 9739:PLK3
uniprot id: A0A2U4BK69
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

9739:MAP6
gene id: 9739:MAP6
uniprot id: A0A2U4C9H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STOP family.
messages: cytoskeleton

9739:CHMP3
gene id: 9739:CHMP3
uniprot id: A0A2U4BXB6
names: Similarity
messages: Belongs to the SNF7 family.

9739:CACNA1D
gene id: 9739:CACNA1D
uniprot id: A0A6J3RYE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. CACNA1D subfamily.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death.

9739:PTGR2
gene id: 9739:PTGR2
uniprot id: A0A2U3V2M3
uniprot id: A0A2U4A7S8
uniprot id: A0A2U4A7T1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADP-dependent oxidoreductase L4BD family.
messages: Cytoplasm
messages: Monomer.

9739:ALDH1B1
gene id: 9739:ALDH1B1
uniprot id: A0A2U4CG69
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

9739:ATP2B2
gene id: 9739:ATP2B2
uniprot id: A0A6J3S307
uniprot id: A0A6J3S312
uniprot id: A0A6J3S369
uniprot id: A0A6J3S3A5
uniprot id: A0A6J3S3Y5
uniprot id: A0A6J3S3Z0
uniprot id: A0A6J3S483
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:B4GALT4
gene id: 9739:B4GALT4
uniprot id: A0A2U4ACL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

9739:PRKAB2
gene id: 9739:PRKAB2
uniprot id: A0A2U4A322
uniprot id: A0A2U4A327
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

9739:ATP8B1
gene id: 9739:ATP8B1
uniprot id: A0A2U4BHH6
uniprot id: A0A2U4BHI4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:HOXD9
gene id: 9739:HOXD9
uniprot id: A0A2U4ACG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

9739:LOC101335037
gene id: 9739:LOC101335037
uniprot id: A0A2U4CJX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

9739:MMP14
gene id: 9739:MMP14
uniprot id: A0A6J3QY22
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.
messages: Cytoplasm
messages: Melanosome

9739:GRB2
gene id: 9739:GRB2
uniprot id: A0A6J3QQM5
names: Subcellular Location Annotation
messages: Endosome
messages: Golgi apparatus
messages: Nucleus

9739:GPR87
gene id: 9739:GPR87
uniprot id: A0A2U3V9B4
uniprot id: A0A2U4B9Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9739:ZDHHC22
gene id: 9739:ZDHHC22
uniprot id: A0A6J3QXY7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9739:FZD5
gene id: 9739:FZD5
uniprot id: A0A2U4BN63
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:TSPAN32
gene id: 9739:TSPAN32
uniprot id: A0A6J3RSI8
names: Subcellular Location Annotation
messages: Membrane

9739:MYH7
gene id: 9739:MYH7
uniprot id: A0A6J3QZB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: myofibril

9739:LOC117313791
gene id: 9739:LOC117313791
uniprot id: A0A6J3RYY5
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

9739:COPB2
gene id: 9739:COPB2
uniprot id: A0A2U3V857
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat COPB2 family.
messages: COPI-coated vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
messages: This coatomer complex protein, essential for Golgi budding and vesicular trafficking, is a selective binding protein (RACK) for protein kinase C, epsilon type. It binds to Golgi membranes in a GTP-dependent manner.

9739:BIRC2
gene id: 9739:BIRC2
uniprot id: A0A6J3RTN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IAP family.
messages: Cytoplasm
messages: Nucleus

9739:LOC101330538
gene id: 9739:LOC101330538
uniprot id: A0A6J3REZ0
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

9739:GATM
gene id: 9739:GATM
uniprot id: A0A2U3V9R1
uniprot id: A0A2U4BCS7
uniprot id: A0A2U4BCS8
uniprot id: A0A2U4BCT5
uniprot id: A0A2U4BCV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the amidinotransferase family.
messages: Homodimer.
messages: Mitochondrion inner membrane
messages: Transamidinase that catalyzes the transfer of the amidino group of L-arginine onto the amino moiety of acceptor metabolites such as glycine, beta-alanine, gamma-aminobutyric acid (GABA) and taurine yielding the corresponding guanidine derivatives. Catalyzes the rate-limiting step of creatine biosynthesis, namely the transfer of the amidino group from L-arginine to glycine to generate guanidinoacetate, which is then methylated by GAMT to form creatine. Provides creatine as a source for ATP generation in tissues with high energy demands, in particular skeletal muscle, heart and brain.

9739:TMEFF2
gene id: 9739:TMEFF2
uniprot id: A0A2U4B1H5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:KCNMA1
gene id: 9739:KCNMA1
uniprot id: A0A6J3Q612
uniprot id: A0A6J3Q619
uniprot id: A0A6J3Q6E1
uniprot id: A0A6J3Q6S8
uniprot id: A0A6J3Q6T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa1.1/KCNMA1 sub-subfamily.
messages: Membrane

9739:LOC109547684
gene id: 9739:LOC109547684
uniprot id: A0A2U4A8D4
names: Subcellular Location Annotation
messages: Nucleus

9739:ACTL10
gene id: 9739:ACTL10
uniprot id: A0A6J3Q1D5
names: Similarity
messages: Belongs to the actin family.

9739:POLR2K
gene id: 9739:POLR2K
uniprot id: A0A2U3V7G4
names: Similarity
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.

9739:SLC10A6
gene id: 9739:SLC10A6
uniprot id: A0A2U3V4W0
uniprot id: A0A2U4AMQ8
uniprot id: A0A2U4AN49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

9739:EBF4
gene id: 9739:EBF4
uniprot id: A0A6J3Q0L7
uniprot id: A0A6J3Q0P3
uniprot id: A0A6J3Q188
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

9739:NOTCH2
gene id: 9739:NOTCH2
uniprot id: A0A2U4A1Y3
uniprot id: A0A2U4A1Y5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

9739:GGNBP2
gene id: 9739:GGNBP2
uniprot id: A0A2U3UZC7
uniprot id: A0A2U4C6B8
uniprot id: A0A2U4C6C8
uniprot id: A0A2U4C6D4
uniprot id: A0A2U4C6D7
uniprot id: A0A2U4C6M0
uniprot id: A0A6J3QK35
names: Function
messages: May be involved in spermatogenesis.

9739:HOOK3
gene id: 9739:HOOK3
uniprot id: A0A2U4A767
uniprot id: A0A6J3QR52
uniprot id: A0A6J3QRL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hook family.
messages: cytoskeleton

9739:PRPF38B
gene id: 9739:PRPF38B
uniprot id: A0A6J3RW24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP38 family.
messages: May be required for pre-mRNA splicing.
messages: Nucleus

9739:NCK2
gene id: 9739:NCK2
uniprot id: A0A6J3PWP6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum

9739:TINAGL1
gene id: 9739:TINAGL1
uniprot id: A0A6J3PY46
uniprot id: A0A6J3PY66
uniprot id: A0A6J3PYD7
names: Similarity
messages: Belongs to the peptidase C1 family.

9739:PSMG2
gene id: 9739:PSMG2
uniprot id: A0A2U3V4J3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PSMG2 family.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1.
messages: Forms a heterodimer with PSMG1.

9739:ANXA6
gene id: 9739:ANXA6
uniprot id: A0A6J3R3M5
uniprot id: A0A6J3R4J7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: May associate with CD21. May regulate the release of Ca(2+) from intracellular stores.
messages: Melanosome

9739:ST8SIA3
gene id: 9739:ST8SIA3
uniprot id: A0A6J3PS90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9739:ST8SIA4
gene id: 9739:ST8SIA4
uniprot id: A0A2U4BSX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9739:LIMS2
gene id: 9739:LIMS2
uniprot id: A0A6J3RN42
uniprot id: A0A6J3RN50
uniprot id: A0A6J3RNF9
uniprot id: A0A6J3RNV6
uniprot id: A0A6J3RPC7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Adapter protein in a cytoplasmic complex linking beta-integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors.
messages: Cell membrane
messages: Part of the heterotrimeric IPP complex composed of integrin-linked kinase (ILK), LIMS1 or LIMS2, and PARVA.
messages: focal adhesion

9739:CPSF7
gene id: 9739:CPSF7
uniprot id: A0A2U4B8G9
uniprot id: A0A2U4B8I4
uniprot id: A0A2U4B8I8
uniprot id: A0A6J3RQS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CPSF6/7 family.
messages: Nucleus

9739:LOC101320771
gene id: 9739:LOC101320771
uniprot id: A0A2U4A0N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9739:NTN4
gene id: 9739:NTN4
uniprot id: A0A6J3S5F4
uniprot id: A0A6J3S6H5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:ADPRHL1
gene id: 9739:ADPRHL1
uniprot id: A0A2U3V4D1
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

9739:SLC46A3
gene id: 9739:SLC46A3
uniprot id: A0A2U3UYT1
uniprot id: A0A2U4BH12
uniprot id: A0A6J3QBQ5
names: Subcellular Location Annotation
messages: Membrane

9739:CHST12
gene id: 9739:CHST12
uniprot id: A0A6J3Q0T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

9739:EIF4E1B
gene id: 9739:EIF4E1B
uniprot id: A0A6J3R878
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

9739:ZNF232
gene id: 9739:ZNF232
uniprot id: A0A2U4AN54
names: Subcellular Location Annotation
messages: Nucleus

9739:TPM1
gene id: 9739:TPM1
uniprot id: A0A2U3V206
uniprot id: A0A2U3V249
uniprot id: A0A2U3V252
uniprot id: A0A2U3V264
uniprot id: A0A2U3V265
uniprot id: A0A2U3V269
uniprot id: A0A2U3V2H6
uniprot id: A0A2U4CCY3
uniprot id: A0A2U4CD10
uniprot id: A0A2U4CD13
uniprot id: A0A2U4CD25
uniprot id: A0A2U4CD30
uniprot id: A0A2U4CD31
uniprot id: A0A2U4CD41
uniprot id: A0A6J3QYQ1
uniprot id: A0A6J3QYQ6
uniprot id: A0A6J3QZ13
uniprot id: A0A6J3QZD1
uniprot id: A0A6J3QZD6
uniprot id: A0A6J3QZK1
uniprot id: A0A6J3QZK4
uniprot id: A0A6J3R0K0
uniprot id: A0A6J3R0K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

9739:ADGRL4
gene id: 9739:ADGRL4
uniprot id: A0A2U4A3X2
uniprot id: A0A2U4A3X7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:DMD
gene id: 9739:DMD
uniprot id: A0A6J3QSR6
uniprot id: A0A6J3QT15
uniprot id: A0A6J3QTR6
names: Subcellular Location Annotation
messages: cytoskeleton

9739:SNRPC
gene id: 9739:SNRPC
uniprot id: A0A2U3V576
uniprot id: A0A2U4CJI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the U1 small nuclear ribonucleoprotein C family.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. snrpc/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates E complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Nucleus
messages: U1 snRNP is composed of the 7 core Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins SNRNP70/U1-70K, SNRPA/U1-A and SNRPC/U1-C. SNRPC/U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA.

9739:FAM118A
gene id: 9739:FAM118A
uniprot id: A0A6J3S475
uniprot id: A0A6J3S4C3
uniprot id: A0A6J3S4C7
uniprot id: A0A6J3S4H0
uniprot id: A0A6J3S4H1
uniprot id: A0A6J3S599
uniprot id: A0A6J3S5K4
names: Similarity
messages: Belongs to the FAM118 family.

9739:ANXA13
gene id: 9739:ANXA13
uniprot id: A0A6J3Q8P1
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

9739:TLX1
gene id: 9739:TLX1
uniprot id: A0A2U4BQQ5
uniprot id: A0A6J3Q6N1
uniprot id: A0A6J3Q705
names: Subcellular Location Annotation
messages: Nucleus

9739:NDOR1
gene id: 9739:NDOR1
uniprot id: A0A2U3V520
uniprot id: A0A2U4B7T6
uniprot id: A0A2U4B801
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Interacts with CIAPIN1; as part of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of CIAPIN1, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. It can also reduce the [2Fe-2S] cluster of CISD1 and activate this protein implicated in Fe/S cluster repair.
messages: perinuclear region

9739:CAMK2A
gene id: 9739:CAMK2A
uniprot id: A0A6J3R3H0
uniprot id: A0A6J3R3N4
uniprot id: A0A6J3R4D4
uniprot id: A0A6J3R5U5
names: Similarity
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

9739:TRABD2A
gene id: 9739:TRABD2A
uniprot id: A0A6J3PX46
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIKI family.
messages: Cell membrane
messages: Divalent metal cations. Mn(2+) or Co(2+).
messages: Membrane
messages: Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation.

9739:PLA2G3
gene id: 9739:PLA2G3
uniprot id: A0A6J3PSG4
uniprot id: A0A6J3PSL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Secreted

9739:SGCZ
gene id: 9739:SGCZ
uniprot id: A0A2U4A717
uniprot id: A0A2U4A765
uniprot id: A0A2U4A7U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

9739:HNRNPA3
gene id: 9739:HNRNPA3
uniprot id: A0A2U4AAR0
uniprot id: A0A6J3RME9
uniprot id: A0A6J3RNF0
names: Subcellular Location Annotation
messages: Nucleus

9739:PRDM5
gene id: 9739:PRDM5
uniprot id: A0A2U4ARP5
uniprot id: A0A2U4AS52
names: Subcellular Location Annotation
messages: Nucleus

9739:AGPAT2
gene id: 9739:AGPAT2
uniprot id: A0A6J3RJZ4
names: Domain
names: Function
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

9739:DBNDD2
gene id: 9739:DBNDD2
uniprot id: A0A6J3Q3R4
uniprot id: A0A6J3Q3Y2
names: Similarity
messages: Belongs to the dysbindin family.

9739:ARG1
gene id: 9739:ARG1
uniprot id: A0A2U3V0A2
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

9739:RHBDF2
gene id: 9739:RHBDF2
uniprot id: A0A6J3QN72
uniprot id: A0A6J3QNC5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

9739:LOC101329720
gene id: 9739:LOC101329720
uniprot id: A0A2U4AMC0
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

9739:AGO2
gene id: 9739:AGO2
uniprot id: A0A6J3Q8J3
uniprot id: A0A6J3Q8J8
uniprot id: A0A6J3Q901
uniprot id: A0A6J3Q9B4
uniprot id: A0A6J3Q9B9
uniprot id: A0A6J3Q9C2
uniprot id: A0A6J3Q9C6
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argonaute family.
messages: Belongs to the argonaute family. Ago subfamily.
messages: Hydroxylated. 4-hydroxylation appears to enhance protein stability but is not required for miRNA-binding or endonuclease activity.
messages: Interacts with DICER1 through its Piwi domain and with TARBP2 during assembly of the RNA-induced silencing complex (RISC). Together, DICER1, AGO2 and TARBP2 constitute the trimeric RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC). Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. Note however that the term RISC has also been used to describe the trimeric RLC/miRLC. The formation of RISC complexes containing siRNAs rather than miRNAs appears to occur independently of DICER1. Interacts with AGO1. Also interacts with DDB1, DDX5, DDX6, DDX20, DHX30, DHX36, DDX47, DHX9, ELAVL, FXR1, GEMIN4, HNRNPF, IGF2BP1, ILF3, IMP8, MATR3, PABPC1, PRMT5, P4HA1, P4HB, RBM4, SART3, TNRC6A, TNRC6B, UPF1 and YBX1. Interacts with the P-body components DCP1A and XRN1. Associates with polysomes and messenger ribonucleoproteins (mNRPs). Interacts with RBM4; the interaction is modulated under stress-induced conditions, occurs under both cell proliferation and differentiation conditions and in an RNA-and phosphorylation-independent manner. Interacts with LIMD1, WTIP and AJUBA. Interacts with TRIM71. Interacts with APOBEC3G in an RNA-dependent manner. Interacts with APOBEC3A, APOBEC3C, APOBEC3F and APOBEC3H. Interacts with DICER1, TARBP2, EIF6, MOV10 and RPL7A (60S ribosome subunit); they form a large RNA-induced silencing complex (RISC). Interacts with FMR1. Interacts with ZFP36.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the mRNA specifically by AGO2. Binding of RISC to a partially complementary mRNA results in silencing through inhibition of translation, and this is independent of endonuclease activity. May inhibit translation initiation by binding to the 7-methylguanosine cap, thereby preventing the recruitment of the translation initiation factor eIF4-E. May also inhibit translation initiation via interaction with EIF6, which itself binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit. The inhibition of translational initiation leads to the accumulation of the affected mRNA in cytoplasmic processing bodies (P-bodies), where mRNA degradation may subsequently occur. In some cases RISC-mediated translational repression is also observed for miRNAs that perfectly match the 3' untranslated region (3'-UTR). Can also up-regulate the translation of specific mRNAs under certain growth conditions. Binds to the AU element of the 3'-UTR of the TNF (TNF-alpha) mRNA and up-regulates translation under conditions of serum starvation. Also required for transcriptional gene silencing (TGS), in which short RNAs known as antigene RNAs or agRNAs direct the transcriptional repression of complementary promoter regions.
messages: The Piwi domain may perform RNA cleavage by a mechanism similar to that of RNase H. However, while RNase H utilizes a triad of Asp-Asp-Glu (DDE) for metal ion coordination, this protein appears to utilize a triad of Asp-Asp-His (DDH).

9739:HNRNPA2B1
gene id: 9739:HNRNPA2B1
uniprot id: A0A2U3V9D2
uniprot id: A0A2U3V9D5
uniprot id: A0A6J3RWS9
names: Subcellular Location Annotation
messages: Cytoplasmic granule

9739:LOC109548098
gene id: 9739:LOC109548098
uniprot id: A0A2U4AFJ0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space
messages: Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

9739:SEPTIN4
gene id: 9739:SEPTIN4
uniprot id: A0A6J3QLY9
uniprot id: A0A6J3QM28
uniprot id: A0A6J3QMN6
uniprot id: A0A6J3QN39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

9739:KDM1A
gene id: 9739:KDM1A
uniprot id: A0A2U4BLL9
uniprot id: A0A2U4BLQ6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the flavin monoamine oxidase family.
messages: Histone demethylase that can demethylate both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me. May play a role in the repression of neuronal genes. Alone, it is unable to demethylate H3K4me on nucleosomes and requires the presence of RCOR1/CoREST to achieve such activity.
messages: Nucleus
messages: The SWIRM domain may act as an anchor site for a histone tail.

9739:ST8SIA6
gene id: 9739:ST8SIA6
uniprot id: A0A2U4B778
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9739:WHAMM
gene id: 9739:WHAMM
uniprot id: A0A2U4C734
uniprot id: A0A6J3R0P6
names: Subcellular Location Annotation
messages: Membrane

9739:ZRANB1
gene id: 9739:ZRANB1
uniprot id: A0A2U4BRD1
uniprot id: A0A2U4BRE1
names: Similarity
messages: Belongs to the peptidase C64 family.

9739:FAM91A1
gene id: 9739:FAM91A1
uniprot id: A0A2U3V1E2
uniprot id: A0A2U4B315
uniprot id: A0A2U4B347
names: Similarity
messages: Belongs to the FAM91 family.

9739:CXCR6
gene id: 9739:CXCR6
uniprot id: A0A2U4CAB5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9739:ACOX1
gene id: 9739:ACOX1
uniprot id: A0A2U3UYI1
uniprot id: A0A2U3UYV6
uniprot id: A0A2U4BMC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

9739:LGMN
gene id: 9739:LGMN
uniprot id: A0A6J3QVR2
names: Similarity
messages: Belongs to the peptidase C13 family.

9739:XCR1
gene id: 9739:XCR1
uniprot id: A0A2U3V714
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9739:LOC109549675
gene id: 9739:LOC109549675
uniprot id: A0A2U4B726
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 6c family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

9739:ZFPM1
gene id: 9739:ZFPM1
uniprot id: A0A6J3QFL8
names: Subcellular Location Annotation
messages: Nucleus

9739:RBL1
gene id: 9739:RBL1
uniprot id: A0A2U4CLJ3
uniprot id: A0A2U4CLJ4
uniprot id: A0A2U4CLJ5
uniprot id: A0A2U4CLS0
uniprot id: A0A6J3Q3K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

9739:NUP210L
gene id: 9739:NUP210L
uniprot id: A0A2U4A1R3
names: Similarity
messages: Belongs to the NUP210 family.

9739:C8B
gene id: 9739:C8B
uniprot id: A0A2U4BXH7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9739:MC4R
gene id: 9739:MC4R
uniprot id: A0A2U3V0W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).

9739:SLC6A15
gene id: 9739:SLC6A15
uniprot id: A0A2U3ZZX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A15 subfamily.
messages: Membrane

9739:HMMR
gene id: 9739:HMMR
uniprot id: A0A2U4C691
uniprot id: A0A2U4C6B7
uniprot id: A0A2U4C6C1
uniprot id: A0A2U4C6C3
uniprot id: A0A2U4C6J6
uniprot id: A0A2U4C6M8
uniprot id: A0A6J3R3Z8
names: Subcellular Location Annotation
messages: spindle

9739:PRKG1
gene id: 9739:PRKG1
uniprot id: A0A6J3Q535
uniprot id: A0A6J3Q5K6
uniprot id: A0A6J3Q5W3
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

9739:BTAF1
gene id: 9739:BTAF1
uniprot id: A0A2U4C259
uniprot id: A0A2U4C291
uniprot id: A0A6J3Q560
names: Subcellular Location Annotation
messages: Nucleus

9739:CCHCR1
gene id: 9739:CCHCR1
uniprot id: A0A6J3RZ60
uniprot id: A0A6J3RZ78
uniprot id: A0A6J3S035
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be a regulator of keratinocyte proliferation or differentiation.
messages: Nucleus

9739:JMJD1C
gene id: 9739:JMJD1C
uniprot id: A0A2U4BDZ6
uniprot id: A0A6J3Q5I4
uniprot id: A0A6J3Q5R9
uniprot id: A0A6J3Q615
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM2 histone demethylase family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code.
messages: Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors.
messages: Nucleus
messages: The JmjC domain and the C6-type zinc-finger are required for the demethylation activity.

9739:CTNND2
gene id: 9739:CTNND2
uniprot id: A0A2U4CMI4
names: Similarity
messages: Belongs to the beta-catenin family.

9739:RPL17
gene id: 9739:RPL17
uniprot id: A0A2U4BHA1
uniprot id: A0A6J3PTY1
uniprot id: A0A6J3PUX6
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

9739:SLC5A6
gene id: 9739:SLC5A6
uniprot id: A0A6J3PXE8
uniprot id: A0A6J3PXG2
uniprot id: A0A6J3PXJ3
uniprot id: A0A6J3PY03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

9739:ITGA4
gene id: 9739:ITGA4
uniprot id: A0A6J3RND5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9739:CCL16
gene id: 9739:CCL16
uniprot id: A0A2U4C6J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

9739:SGSM3
gene id: 9739:SGSM3
uniprot id: A0A6J3S4L9
uniprot id: A0A6J3S4M4
uniprot id: A0A6J3S4R4
uniprot id: A0A6J3S4W8
uniprot id: A0A6J3S5R9
uniprot id: A0A6J3S5S3
uniprot id: A0A6J3S5Z6
uniprot id: A0A6J3S602
names: Similarity
messages: Belongs to the small G protein signaling modulator family.

9739:TXNRD2
gene id: 9739:TXNRD2
uniprot id: A0A2U4A5P7
uniprot id: A0A2U4A6F0
uniprot id: A0A6J3PT66
uniprot id: A0A6J3PTC8
uniprot id: A0A6J3PTD5
uniprot id: A0A6J3PTR5
uniprot id: A0A6J3PTU3
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

9739:SLC35A5
gene id: 9739:SLC35A5
uniprot id: A0A2U4AC02
uniprot id: A0A2U4ACH8
uniprot id: A0A6J3RA24
uniprot id: A0A6J3RAS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9739:SKAP2
gene id: 9739:SKAP2
uniprot id: A0A2U4AM43
names: Similarity
messages: Belongs to the SKAP family.

9739:LOC109548023
gene id: 9739:LOC109548023
uniprot id: A0A6J3RLB0
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

9739:UBAC2
gene id: 9739:UBAC2
uniprot id: A0A2U4A5Z2
uniprot id: A0A2U4A5Z4
uniprot id: A0A2U4A640
names: Subcellular Location Annotation
messages: Membrane

9739:TSN
gene id: 9739:TSN
uniprot id: A0A2U3V9F7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the translin family.
messages: DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots.
messages: Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand.
messages: Nucleus
messages: Ring-shaped heterooctamer of six TSN and two TSNAX subunits, DNA/RNA binding occurs inside the ring.

9739:TMEM161B
gene id: 9739:TMEM161B
uniprot id: A0A2U3V5D0
uniprot id: A0A2U4AWF0
uniprot id: A0A6J3R2B9
uniprot id: A0A6J3R2T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM161 family.
messages: Membrane

9739:HS6ST2
gene id: 9739:HS6ST2
uniprot id: A0A6J3QUL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

9739:STRIP2
gene id: 9739:STRIP2
uniprot id: A0A2U3V955
uniprot id: A0A6J3RX46
uniprot id: A0A6J3RXA2
uniprot id: A0A6J3RXX0
names: Similarity
messages: Belongs to the STRIP family.

9739:HSDL2
gene id: 9739:HSDL2
uniprot id: A0A2U4C942
uniprot id: A0A2U4C944
uniprot id: A0A2U4C946
uniprot id: A0A2U4C958
uniprot id: A0A6J3RHY9
names: Subcellular Location Annotation
messages: Peroxisome

9739:SLC25A20
gene id: 9739:SLC25A20
uniprot id: A0A2U3V3R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9739:MRPL41
gene id: 9739:MRPL41
uniprot id: A0A2U3V6Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL41 family.
messages: Mitochondrion

9739:SOX3
gene id: 9739:SOX3
uniprot id: A0A6J3QSW0
names: Subcellular Location Annotation
messages: Nucleus

9739:INPPL1
gene id: 9739:INPPL1
uniprot id: A0A6J3RUQ1
uniprot id: A0A6J3RUU4
names: Similarity
names: Subcellular Location Annotation
messages: Basal cell membrane
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.
messages: Membrane
messages: Nucleus speckle
messages: filopodium
messages: lamellipodium
messages: spindle pole

9739:LOC117307501
gene id: 9739:LOC117307501
uniprot id: A0A2U4C4B4
uniprot id: A0A6J3QR53
uniprot id: A0A6J3QRN8
uniprot id: A0A6J3QRP9
uniprot id: A0A6J3QUQ4
names: Similarity
messages: Belongs to the CD99 family.

9739:GPRC6A
gene id: 9739:GPRC6A
uniprot id: A0A2U3VAP1
names: Subcellular Location Annotation
messages: Membrane

9739:CCNI
gene id: 9739:CCNI
uniprot id: A0A2U3V397
uniprot id: A0A2U4B520
uniprot id: A0A2U4B5G1
uniprot id: A0A6J3RE34
names: Similarity
messages: Belongs to the cyclin family.

9739:SMAD6
gene id: 9739:SMAD6
uniprot id: A0A6J3QZ14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

9739:LOC101337498
gene id: 9739:LOC101337498
uniprot id: A0A6J3QET9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tigger transposable element derived protein family.
messages: Nucleus

9739:MRPS17
gene id: 9739:MRPS17
uniprot id: A0A2U3V945
uniprot id: A0A2U4A8L6
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

9739:RBX1
gene id: 9739:RBX1
uniprot id: A0A6J3S4V0
names: Similarity
messages: Belongs to the RING-box family.

9739:NLGN2
gene id: 9739:NLGN2
uniprot id: A0A6J3QKG3
uniprot id: A0A6J3QL72
uniprot id: A0A6J3QLK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

9739:MARCHF9
gene id: 9739:MARCHF9
uniprot id: A0A6J3S5S5
names: Subcellular Location Annotation
messages: Membrane

9739:CHMP2A
gene id: 9739:CHMP2A
uniprot id: A0A2U3V3F2
names: Similarity
messages: Belongs to the SNF7 family.

9739:MUC2
gene id: 9739:MUC2
uniprot id: A0A6J3RRN1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:NIF3L1
gene id: 9739:NIF3L1
uniprot id: A0A2U4BNE0
uniprot id: A0A2U4BNK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
messages: Cytoplasm
messages: Homodimer. Interacts with COPS2. Interacts with THOC7.
messages: May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation.
messages: Nucleus

9739:PGLS
gene id: 9739:PGLS
uniprot id: A0A2U3UZP3
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

9739:SLC15A4
gene id: 9739:SLC15A4
uniprot id: A0A2U4BWU6
uniprot id: A0A2U4BWV0
uniprot id: A0A2U4BWV6
uniprot id: A0A2U4BWW9
uniprot id: A0A2U4BWY7
uniprot id: A0A2U4BWZ5
uniprot id: A0A2U4BX38
uniprot id: A0A2U4BX50
uniprot id: A0A6J3PR63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

9739:LOC109551487
gene id: 9739:LOC109551487
uniprot id: A0A2U3V257
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9739:EPHA7
gene id: 9739:EPHA7
uniprot id: A0A2U4AVK5
uniprot id: A0A2U4AVL5
uniprot id: A0A2U4AVN6
uniprot id: A0A6J3S8R7
names: Subcellular Location Annotation
messages: Membrane

9739:PCK2
gene id: 9739:PCK2
uniprot id: A0A6J3QXR1
uniprot id: A0A6J3QXW1
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.

9739:MCM7
gene id: 9739:MCM7
uniprot id: A0A2U3V416
uniprot id: A0A2U4AYW8
uniprot id: A0A2U4AZC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Nucleus

9739:DRAM2
gene id: 9739:DRAM2
uniprot id: A0A2U4A2P9
uniprot id: A0A6J3RTL6
names: Subcellular Location Annotation
messages: Membrane

9739:SLC24A2
gene id: 9739:SLC24A2
uniprot id: A0A2U4BB56
uniprot id: A0A2U4BB88
uniprot id: A0A6J3RHH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

9739:CEBPZ
gene id: 9739:CEBPZ
uniprot id: A0A2U4BZ94
names: Similarity
messages: Belongs to the CBF/MAK21 family.

9739:GRIA2
gene id: 9739:GRIA2
uniprot id: A0A2U4AMW5
uniprot id: A0A2U4AMZ9
uniprot id: A0A2U4ANA3
uniprot id: A0A6J3RFX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

9739:SVBP
gene id: 9739:SVBP
uniprot id: A0A2U4BK63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVBP family.
messages: Secreted
messages: cytoskeleton

9739:GGPS1
gene id: 9739:GGPS1
uniprot id: A0A2U4BVD4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

9739:PHPT1
gene id: 9739:PHPT1
uniprot id: A0A6J3RK01
names: Function
names: Similarity
messages: Belongs to the janus family.
messages: Exhibits phosphohistidine phosphatase activity.

9739:LOC101326910
gene id: 9739:LOC101326910
uniprot id: A0A2U3V341
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCC3 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex), mediating cytochrome b recruitment and probably stabilization within the complex. Thereby, plays an important role in ATP production by mitochondria. Cardiolipin-binding protein, it may also control the cardiolipin composition of mitochondria membranes and their morphology.

9739:CFAP157
gene id: 9739:CFAP157
uniprot id: A0A6J3RLI5
names: Similarity
messages: Belongs to the CFAP157 family.

9739:LOC101320699
gene id: 9739:LOC101320699
uniprot id: A0A2U4A211
names: Similarity
messages: Belongs to the BEX family.

9739:DGKG
gene id: 9739:DGKG
uniprot id: A0A2U4C8V5
uniprot id: A0A6J3R9F6
uniprot id: A0A6J3R9P5
uniprot id: A0A6J3RA64
uniprot id: A0A6J3RA69
uniprot id: A0A6J3RAK2
uniprot id: A0A6J3RCA0
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

9739:HEG1
gene id: 9739:HEG1
uniprot id: A0A2U4AC58
uniprot id: A0A6J3RA07
uniprot id: A0A6J3RAH2
uniprot id: A0A6J3RAV1
uniprot id: A0A6J3RCK2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:MRPL12
gene id: 9739:MRPL12
uniprot id: A0A2U3UYP3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL12 family.

9739:CLDN17
gene id: 9739:CLDN17
uniprot id: A0A2U4ADF2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9739:INPP5K
gene id: 9739:INPP5K
uniprot id: A0A2U4ANE9
uniprot id: A0A2U4ANH6
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.

9739:PSMC6
gene id: 9739:PSMC6
uniprot id: A0A2U3V2U4
uniprot id: A0A2U4AF40
names: Similarity
messages: Belongs to the AAA ATPase family.

9739:TMEFF1
gene id: 9739:TMEFF1
uniprot id: A0A2U4CGY3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:LOC101325520
gene id: 9739:LOC101325520
uniprot id: A0A6J3S7T3
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

9739:TRAPPC6A
gene id: 9739:TRAPPC6A
uniprot id: A0A6J3QCZ4
uniprot id: A0A6J3QD01
uniprot id: A0A6J3QD06
uniprot id: A0A6J3QD34
uniprot id: A0A6J3QD46
uniprot id: A0A6J3QD52
uniprot id: A0A6J3QD56
uniprot id: A0A6J3QDD8
uniprot id: A0A6J3QDE3
uniprot id: A0A6J3QDK7
uniprot id: A0A6J3QDL3
uniprot id: A0A6J3QDM0
uniprot id: A0A6J3QDU6
uniprot id: A0A6J3QDV1
uniprot id: A0A6J3QDW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: cis-Golgi network

9739:CLIC4
gene id: 9739:CLIC4
uniprot id: A0A2U4BLH4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

9739:ARSI
gene id: 9739:ARSI
uniprot id: A0A2U3V0F5
names: Similarity
messages: Belongs to the sulfatase family.

9739:RHBDD1
gene id: 9739:RHBDD1
uniprot id: A0A2U4ADR7
uniprot id: A0A6J3RL35
names: Subcellular Location Annotation
messages: Membrane

9739:OC90
gene id: 9739:OC90
uniprot id: A0A6J3Q9G7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

9739:TRIQK
gene id: 9739:TRIQK
uniprot id: A0A2U4AIS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIQK family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:CRELD1
gene id: 9739:CRELD1
uniprot id: A0A2U3UZR6
uniprot id: A0A2U4C447
uniprot id: A0A6J3S466
names: Caution
names: Similarity
messages: Belongs to the CRELD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:DDI1
gene id: 9739:DDI1
uniprot id: A0A2U3V7Q1
names: Similarity
messages: Belongs to the DDI1 family.

9739:GRAMD1C
gene id: 9739:GRAMD1C
uniprot id: A0A6J3RA15
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:DDX43
gene id: 9739:DDX43
uniprot id: A0A2U4AV55
uniprot id: A0A2U4AVK8
uniprot id: A0A6J3S917
uniprot id: A0A6J3SA47
names: Similarity
messages: Belongs to the DEAD box helicase family.

9739:LOC109548582
gene id: 9739:LOC109548582
uniprot id: A0A2U4AMY3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

9739:SEPTIN11
gene id: 9739:SEPTIN11
uniprot id: A0A2U4B519
uniprot id: A0A2U4B568
uniprot id: A0A2U4B5F6
uniprot id: A0A6J3RE55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

9739:LOC101321459
gene id: 9739:LOC101321459
uniprot id: A0A6J3PUZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

9739:LOC101326305
gene id: 9739:LOC101326305
uniprot id: A0A6J3QSS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

9739:C6
gene id: 9739:C6
uniprot id: A0A2U4AUS5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Component of the membrane attack complex (MAC). MAC assembly is initiated by proteolytic cleavage of C5 into C5a and C5b. C5b binds sequentially C6, C7, C8 and 12-14 copies of the pore-forming subunit C9.
messages: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9739:MYCBP2
gene id: 9739:MYCBP2
uniprot id: A0A2U4A609
uniprot id: A0A2U4A614
uniprot id: A0A2U4A663
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RING-Cys relay (RCR) family.
messages: axon

9739:CASKIN1
gene id: 9739:CASKIN1
uniprot id: A0A6J3PYJ9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

9739:LOC101324605
gene id: 9739:LOC101324605
uniprot id: A0A6J3RNJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

9739:ISCU
gene id: 9739:ISCU
uniprot id: A0A2U3V299
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Mitochondrial scaffold protein, of the core iron-sulfur cluster (ISC) assembly complex, that provides the structural architecture on which the [2Fe-2S] clusters are assembled. The core iron-sulfur cluster (ISC) assembly complex is involved in the de novo synthesis of a [2Fe-2S] cluster, the first step of the mitochondrial iron-sulfur protein biogenesis. This process is initiated by the cysteine desulfurase complex (NFS1:LYRM4:NDUFAB1) that produces persulfide which is delivered on the scaffold protein ISCU in a FXN-dependent manner. Then this complex is stabilized by FDX2 which provides reducing equivalents to accomplish the [2Fe-2S] cluster assembly. Finally, the [2Fe-2S] cluster is transferred from ISCU to chaperone proteins, including HSCB, HSPA9 and GLRX5. Exists as two slow interchanging conformational states, a structured (S) and disordered (D) form. May modulate NFS1 desulfurase activity in a zinc-dependent manner. Modulates the interaction between FXN and the cysteine desulfurase complex.

9739:TMEM126A
gene id: 9739:TMEM126A
uniprot id: A0A2U3UZ70
names: Subcellular Location Annotation
messages: Membrane

9739:NR1H4
gene id: 9739:NR1H4
uniprot id: A0A6J3S3V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

9739:TRPM5
gene id: 9739:TRPM5
uniprot id: A0A6J3RSQ5
names: Subcellular Location Annotation
messages: Membrane

9739:UBE2U
gene id: 9739:UBE2U
uniprot id: A0A2U4A1J8
uniprot id: A0A2U4A2G8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9739:GCSH
gene id: 9739:GCSH
uniprot id: A0A2U4BSY5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

9739:NRP1
gene id: 9739:NRP1
uniprot id: A0A2U4B6S3
uniprot id: A0A6J3R0L6
uniprot id: A0A6J3R0X9
uniprot id: A0A6J3R1E9
names: Caution
names: Similarity
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:HNRNPH1
gene id: 9739:HNRNPH1
uniprot id: A0A2U4BIC0
uniprot id: A0A2U4BIC6
uniprot id: A0A2U4BID5
uniprot id: A0A2U4BIE3
uniprot id: A0A2U4BIE9
uniprot id: A0A2U4BII3
uniprot id: A0A2U4BIJ0
uniprot id: A0A2U4BIR9
uniprot id: A0A6J3R451
uniprot id: A0A6J3R456
uniprot id: A0A6J3R4D7
uniprot id: A0A6J3R4E1
uniprot id: A0A6J3R4T6
uniprot id: A0A6J3R4U1
uniprot id: A0A6J3R541
uniprot id: A0A6J3R6K9
names: Subcellular Location Annotation
messages: nucleoplasm

9739:CLCA2
gene id: 9739:CLCA2
uniprot id: A0A2U3V5T8
uniprot id: A0A2U4A2F3
names: Similarity
messages: Belongs to the CLCR family.

9739:NFE2L2
gene id: 9739:NFE2L2
uniprot id: A0A2U3V1X0
uniprot id: A0A2U4AAH4
uniprot id: A0A2U4AAQ5
uniprot id: A0A2U4AB32
uniprot id: A0A6J3RMX4
names: Similarity
messages: Belongs to the bZIP family. CNC subfamily.

9739:LOC117312613
gene id: 9739:LOC117312613
uniprot id: A0A6J3RGY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

9739:LOC101317974
gene id: 9739:LOC101317974
uniprot id: A0A6J3QK32
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9739:ASPN
gene id: 9739:ASPN
uniprot id: A0A2U4BS45
uniprot id: A0A2U4BSE7
uniprot id: A0A6J3RG23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: extracellular matrix

9739:ESRRB
gene id: 9739:ESRRB
uniprot id: A0A6J3R137
uniprot id: A0A6J3R1C8
uniprot id: A0A6J3R1L2
uniprot id: A0A6J3R375
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

9739:CWC15
gene id: 9739:CWC15
uniprot id: A0A2U4AEY4
names: Similarity
messages: Belongs to the CWC15 family.

9739:IL17RA
gene id: 9739:IL17RA
uniprot id: A0A2U4AKC8
uniprot id: A0A6J3S7Y3
uniprot id: A0A6J3S884
uniprot id: A0A6J3S8H7
uniprot id: A0A6J3S8I1
uniprot id: A0A6J3S9K1
uniprot id: A0A6J3S9K7
uniprot id: A0A6J3S9P6
uniprot id: A0A6J3S9Q1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9739:GPCPD1
gene id: 9739:GPCPD1
uniprot id: A0A2U3V5H7
uniprot id: A0A2U4BV73
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

9739:WTAP
gene id: 9739:WTAP
uniprot id: A0A6J3SB23
uniprot id: A0A6J3SB54
names: Similarity
messages: Belongs to the fl(2)d family.

9739:LOC117308494
gene id: 9739:LOC117308494
uniprot id: A0A6J3Q6I8
names: Similarity
messages: Belongs to the fl(2)d family.

9739:NXPH4
gene id: 9739:NXPH4
uniprot id: A0A6J3S5X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

9739:RPAP1
gene id: 9739:RPAP1
uniprot id: A0A6J3QXY9
uniprot id: A0A6J3QYD3
uniprot id: A0A6J3QZW7
names: Similarity
messages: Belongs to the RPAP1 family.

9739:LOC101330762
gene id: 9739:LOC101330762
uniprot id: A0A6J3RCR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Membrane

9739:DNASE2
gene id: 9739:DNASE2
uniprot id: A0A6J3R840
names: Similarity
messages: Belongs to the DNase II family.

9739:CPEB1
gene id: 9739:CPEB1
uniprot id: A0A2U4C7X0
names: Similarity
messages: Belongs to the RRM CPEB family.

9739:CDC37L1
gene id: 9739:CDC37L1
uniprot id: A0A2U3V6P1
uniprot id: A0A2U4BB92
uniprot id: A0A6J3RHB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

9739:METTL11B
gene id: 9739:METTL11B
uniprot id: A0A2U3V828
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

9739:FEZ1
gene id: 9739:FEZ1
uniprot id: A0A6J3RSV7
uniprot id: A0A6J3RT42
uniprot id: A0A6J3RTB0
names: Similarity
messages: Belongs to the zygin family.

9739:LOC101334750
gene id: 9739:LOC101334750
uniprot id: A0A6J3S9G2
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

9739:RICTOR
gene id: 9739:RICTOR
uniprot id: A0A2U4AXH2
uniprot id: A0A2U4AXI7
uniprot id: A0A2U4AXK9
uniprot id: A0A6J3R1Z4
uniprot id: A0A6J3R293
uniprot id: A0A6J3R3X1
names: Similarity
messages: Belongs to the RICTOR family.

9739:LOC101329335
gene id: 9739:LOC101329335
uniprot id: A0A2U4CD43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9739:RPL10A
gene id: 9739:RPL10A
uniprot id: A0A2U4CIY4
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

9739:FOXE3
gene id: 9739:FOXE3
uniprot id: A0A6J3R3Y7
names: Subcellular Location Annotation
messages: Nucleus

9739:METTL26
gene id: 9739:METTL26
uniprot id: A0A2U3VAH1
uniprot id: A0A2U4AQE9
names: Similarity
messages: Belongs to the UPF0585 family.

9739:GABRG1
gene id: 9739:GABRG1
uniprot id: A0A2U4AS56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9739:PDCL
gene id: 9739:PDCL
uniprot id: A0A2U4CHB5
names: Similarity
messages: Belongs to the phosducin family.

9739:ADSL
gene id: 9739:ADSL
uniprot id: A0A2U3V6J1
uniprot id: A0A2U4C1M7
uniprot id: A0A2U4C1R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

9739:FAM83H
gene id: 9739:FAM83H
uniprot id: A0A6J3Q950
uniprot id: A0A6J3Q955
names: Similarity
messages: Belongs to the FAM83 family.

9739:OAS2
gene id: 9739:OAS2
uniprot id: A0A6J3PRZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-5A synthase family.
messages: Cytoplasm

9739:GPR35
gene id: 9739:GPR35
uniprot id: A0A6J3RL00
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9739:MYO1E
gene id: 9739:MYO1E
uniprot id: A0A2U4CBX8
uniprot id: A0A6J3QZ06
uniprot id: A0A6J3QZC0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

9739:LOC117313528
gene id: 9739:LOC117313528
uniprot id: A0A6J3RVK5
names: Similarity
messages: Belongs to the eukaryotic mitochondrial porin family.

9739:LOC117310239
gene id: 9739:LOC117310239
uniprot id: A0A6J3QSA6
names: Similarity
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.

9739:LOC101329902
gene id: 9739:LOC101329902
uniprot id: A0A6J3Q6E9
names: Similarity
messages: Belongs to the RING-box family.

9739:GAB2
gene id: 9739:GAB2
uniprot id: A0A2U4CFZ3
uniprot id: A0A2U4CG35
names: Similarity
messages: Belongs to the GAB family.

9739:MEA1
gene id: 9739:MEA1
uniprot id: A0A2U3V6D0
names: Function
messages: May play an important role in spermatogenesis and/or testis development.

9739:MYOG
gene id: 9739:MYOG
uniprot id: A0A2U3V927
names: Subcellular Location Annotation
messages: Nucleus

9739:CALB2
gene id: 9739:CALB2
uniprot id: A0A6J3QFG9
names: Function
names: Similarity
messages: Belongs to the calbindin family.
messages: Calretinin is a calcium-binding protein which is abundant in auditory neurons.

9739:ENY2
gene id: 9739:ENY2
uniprot id: A0A2U3V914
uniprot id: A0A2U4BX91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ENY2 family.
messages: Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2), composed of at least ENY2, GANP, PCID2, DSS1, and either centrin CETN2 or CETN3. TREX-2 contains 2 ENY2 chains. The TREX-2 complex interacts with the nucleoporin NUP153. Component of some SAGA transcription coactivator-HAT complexes, at least composed of ATXN7, ATXN7L3, ENY2, GCN5L2, SUPT3H, TAF10, TRRAP and USP22. Within the SAGA complex, ENY2, ATXN7, ATXN7L3, and USP22 form an additional subcomplex of SAGA called the DUB module (deubiquitination module). Interacts directly with ATXN7L3, GANP and with the RNA polymerase II. Interacts strongly with ATXN7L3 and ATXN7L3B.
messages: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
messages: nucleoplasm

9739:ACTL6A
gene id: 9739:ACTL6A
uniprot id: A0A6J3R962
names: Similarity
messages: Belongs to the actin family.

9739:ATP6V1F
gene id: 9739:ATP6V1F
uniprot id: A0A2U4AFT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase F subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

9739:TRMT6
gene id: 9739:TRMT6
uniprot id: A0A2U4BUX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRM6/GCD10 family.
messages: Nucleus

9739:PPARGC1B
gene id: 9739:PPARGC1B
uniprot id: A0A6J3R416
uniprot id: A0A6J3R5R5
names: Subcellular Location Annotation
messages: Nucleus

9739:TSPAN15
gene id: 9739:TSPAN15
uniprot id: A0A6J3Q6K6
uniprot id: A0A6J3Q6P2
uniprot id: A0A6J3Q716
uniprot id: A0A6J3Q7E3
uniprot id: A0A6J3Q7E7
uniprot id: A0A6J3Q7F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9739:SLC6A20
gene id: 9739:SLC6A20
uniprot id: A0A6J3S133
uniprot id: A0A6J3S1S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

9739:LOC101317899
gene id: 9739:LOC101317899
uniprot id: A0A6J3Q3I7
names: Similarity
messages: Belongs to the universal ribosomal protein uS10 family.

9739:LOC101328760
gene id: 9739:LOC101328760
uniprot id: A0A6J3RYA3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9739:HSPB1
gene id: 9739:HSPB1
uniprot id: A0A2U4CPT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Nucleus
messages: spindle

9739:MCM10
gene id: 9739:MCM10
uniprot id: A0A2U4B711
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM10 family.
messages: Nucleus

9739:SUMO2
gene id: 9739:SUMO2
uniprot id: A0A2U4BMB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

9739:ELL
gene id: 9739:ELL
uniprot id: A0A6J3R5L2
uniprot id: A0A6J3R7M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

9739:SPATA6L
gene id: 9739:SPATA6L
uniprot id: A0A2U4BAU8
uniprot id: A0A2U4BAV3
uniprot id: A0A2U4BB79
uniprot id: A0A6J3RGU0
names: Similarity
messages: Belongs to the SPATA6 family.

9739:MARK2
gene id: 9739:MARK2
uniprot id: A0A6J3RPZ8
uniprot id: A0A6J3RQC4
uniprot id: A0A6J3RQC9
uniprot id: A0A6J3RQD8
uniprot id: A0A6J3RQE2
uniprot id: A0A6J3RR06
uniprot id: A0A6J3RR10
uniprot id: A0A6J3RR13
uniprot id: A0A6J3RR14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

9739:MYLK2
gene id: 9739:MYLK2
uniprot id: A0A6J3Q121
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cytoplasm
messages: May interact with centrin.

9739:USP28
gene id: 9739:USP28
uniprot id: A0A6J3RU02
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

9739:CXCL10
gene id: 9739:CXCL10
uniprot id: A0A2U3V9N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

9739:SENP5
gene id: 9739:SENP5
uniprot id: A0A2U4AB80
uniprot id: A0A2U4ABB8
uniprot id: A0A2U4ABC3
uniprot id: A0A2U4ABD7
uniprot id: A0A2U4ABK2
uniprot id: A0A2U4ABK8
uniprot id: A0A2U4ABW1
uniprot id: A0A2U4ABW5
uniprot id: A0A6J3R9U1
uniprot id: A0A6J3RAB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C48 family.
messages: nucleolus

9739:SRFBP1
gene id: 9739:SRFBP1
uniprot id: A0A6J3R3F6
uniprot id: A0A6J3R4T4
names: Function
names: Subunit
messages: Interacts with SRF. Forms complexes with SRF and SRF cofactors ARID2, MYOCD and NKX2-5. Interacts with the N-terminus of SLC2A4.
messages: May be involved in regulating transcriptional activation of cardiac genes during the aging process. May play a role in biosynthesis and/or processing of SLC2A4 in adipose cells.

9739:CLDN3
gene id: 9739:CLDN3
uniprot id: A0A2U3UZ38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the claudin family.
messages: Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN1 and CLDN2 homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9739:IDH3G
gene id: 9739:IDH3G
uniprot id: A0A6J3QT97
uniprot id: A0A6J3QTU1
uniprot id: A0A6J3QU26
uniprot id: A0A6J3QU95
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

9739:GPR142
gene id: 9739:GPR142
uniprot id: A0A2U3V6E1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9739:GNG11
gene id: 9739:GNG11
uniprot id: A0A2U3VA33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

9739:CTSO
gene id: 9739:CTSO
uniprot id: A0A2U4AM51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

9739:P2RY4
gene id: 9739:P2RY4
uniprot id: A0A6J3QSJ0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9739:LOC101328902
gene id: 9739:LOC101328902
uniprot id: A0A2U4C948
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

9739:ALDH2
gene id: 9739:ALDH2
uniprot id: A0A2U3V1P9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

9739:ITGA5
gene id: 9739:ITGA5
uniprot id: A0A6J3S690
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9739:C16H10orf120
gene id: 9739:C16H10orf120
uniprot id: A0A6J3Q4Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM24 family.
messages: Secreted

9739:BTF3
gene id: 9739:BTF3
uniprot id: A0A2U3V6K6
uniprot id: A0A2U3V6L7
uniprot id: A0A2U4AWR8
uniprot id: A0A2U4AWS6
uniprot id: A0A2U4AWS9
names: Similarity
messages: Belongs to the NAC-beta family.

9739:CHST13
gene id: 9739:CHST13
uniprot id: A0A6J3S3M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

9739:EIF4G3
gene id: 9739:EIF4G3
uniprot id: A0A2U4A0A9
uniprot id: A0A2U4A0B1
uniprot id: A0A2U4A0B4
uniprot id: A0A2U4A0C7
uniprot id: A0A2U4A0D4
uniprot id: A0A2U4A1A6
uniprot id: A0A2U4A1B1
uniprot id: A0A6J3Q5Q8
uniprot id: A0A6J3Q5T9
uniprot id: A0A6J3Q649
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4G family.

9739:LOC101322844
gene id: 9739:LOC101322844
uniprot id: A0A6J3RM31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

9739:SLC16A2
gene id: 9739:SLC16A2
uniprot id: A0A6J3QTC0
uniprot id: A0A6J3QTX2
names: Subcellular Location Annotation
messages: Membrane

9739:ASAH2
gene id: 9739:ASAH2
uniprot id: A0A2U4BHM8
uniprot id: A0A6J3Q653
names: Similarity
messages: Belongs to the neutral ceramidase family.

9739:LOC117310101
gene id: 9739:LOC117310101
uniprot id: A0A6J3QRQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:MAP3K14
gene id: 9739:MAP3K14
uniprot id: A0A6J3QNH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Cytoplasm
messages: Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity.

9739:LOC117313928
gene id: 9739:LOC117313928
uniprot id: A0A6J3S1Q5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:NMBR
gene id: 9739:NMBR
uniprot id: A0A2U4CNF5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9739:ITM2B
gene id: 9739:ITM2B
uniprot id: A0A2U3V3N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

9739:LOC109548804
gene id: 9739:LOC109548804
uniprot id: A0A6J3RFV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL15 family.
messages: Cytoplasm

9739:PSD
gene id: 9739:PSD
uniprot id: A0A6J3Q767
uniprot id: A0A6J3Q7Z9
names: Subcellular Location Annotation
messages: Membrane
messages: ruffle membrane

9739:PLPP3
gene id: 9739:PLPP3
uniprot id: A0A2U4BXM7
uniprot id: A0A2U4BXT1
uniprot id: A0A2U4BXU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

9739:PRKACB
gene id: 9739:PRKACB
uniprot id: A0A2U3V5D9
uniprot id: A0A2U3V5S7
uniprot id: A0A2U4A3Q3
uniprot id: A0A2U4A3Q6
uniprot id: A0A2U4A3R1
uniprot id: A0A6J3RZT2
uniprot id: A0A6J3S006
uniprot id: A0A6J3S027
uniprot id: A0A6J3S0D4
uniprot id: A0A6J3S0V5
uniprot id: A0A6J3S0X0
uniprot id: A0A6J3S0X9
uniprot id: A0A6J3S0Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.
messages: Nucleus

9739:RHOT2
gene id: 9739:RHOT2
uniprot id: A0A6J3Q2C0
uniprot id: A0A6J3Q2C6
uniprot id: A0A6J3Q2I7
uniprot id: A0A6J3Q2I9
uniprot id: A0A6J3Q2N0
uniprot id: A0A6J3Q2N5
uniprot id: A0A6J3Q326
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking.
messages: Mitochondrion outer membrane

9739:TIPIN
gene id: 9739:TIPIN
uniprot id: A0A2U4CFH9
uniprot id: A0A2U4CFN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSM3 family.
messages: Nucleus
messages: Plays an important role in the control of DNA replication and the maintenance of replication fork stability.

9739:TMCO5A
gene id: 9739:TMCO5A
uniprot id: A0A2U3V3V8
names: Subcellular Location Annotation
messages: Membrane

9739:LOC101331853
gene id: 9739:LOC101331853
uniprot id: A0A6J3RYI1
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

9739:SLFN11
gene id: 9739:SLFN11
uniprot id: A0A2U4C5Z3
names: Similarity
messages: Belongs to the Schlafen family. Subgroup III subfamily.

9739:LOC109547492
gene id: 9739:LOC109547492
uniprot id: A0A2U3V528
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

9739:EIF3H
gene id: 9739:EIF3H
uniprot id: A0A2U4B379
uniprot id: A0A2U4B3B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit H family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with RNF139; the interaction leads to protein translation inhibitions in a ubiquitination-dependent manner.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm

9739:GTF2F2
gene id: 9739:GTF2F2
uniprot id: A0A6J3QBQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB.

9739:PIWIL4
gene id: 9739:PIWIL4
uniprot id: A0A2U4AEH8
names: Similarity
messages: Belongs to the argonaute family.

9739:JAK3
gene id: 9739:JAK3
uniprot id: A0A6J3R4U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system

9739:LOC101335834
gene id: 9739:LOC101335834
uniprot id: A0A140GN60
names: Similarity
messages: Belongs to the globin family.

9739:TNKS
gene id: 9739:TNKS
uniprot id: A0A2U3UYI9
uniprot id: A0A2U4A7J4
names: Function
names: Similarity
messages: Belongs to the ARTD/PARP family.
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

9739:HGF
gene id: 9739:HGF
uniprot id: A0A2U4BS66
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Dimer of an alpha chain and a beta chain linked by a disulfide bond. Interacts with SRPX2; the interaction increases HGF mitogenic activity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization.

9739:CENPN
gene id: 9739:CENPN
uniprot id: A0A2U4BSR9
uniprot id: A0A2U4BST3
uniprot id: A0A2U4BT23
uniprot id: A0A2U4BT48
uniprot id: A0A2U4BT52
uniprot id: A0A6J3QD07
names: Similarity
messages: Belongs to the CENP-N/CHL4 family.

9739:TTC9B
gene id: 9739:TTC9B
uniprot id: A0A2U3V2I0
names: Similarity
messages: Belongs to the TTC9 family.

9739:SLC35E1
gene id: 9739:SLC35E1
uniprot id: A0A2U4CMZ5
names: Subcellular Location Annotation
messages: Membrane

9739:MRPL46
gene id: 9739:MRPL46
uniprot id: A0A2U3V7L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL46 family.
messages: Mitochondrion

9739:CTPS2
gene id: 9739:CTPS2
uniprot id: A0A2U4AJM0
uniprot id: A0A2U4AJM2
uniprot id: A0A2U4AJN3
uniprot id: A0A2U4AJN5
names: Caution
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:TERF1
gene id: 9739:TERF1
uniprot id: A0A2U4AID4
uniprot id: A0A2U4AID5
uniprot id: A0A2U4AIM5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.
messages: Homodimer.
messages: Nucleus
messages: telomere

9739:HECTD1
gene id: 9739:HECTD1
uniprot id: A0A2U4AF65
uniprot id: A0A2U4AF68
uniprot id: A0A2U4AF75
uniprot id: A0A2U4AFC8
uniprot id: A0A2U4AFM7
names: Function
names: Similarity
messages: Belongs to the UPL family. K-HECT subfamily.
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

9739:ATP2B3
gene id: 9739:ATP2B3
uniprot id: A0A6J3QS35
uniprot id: A0A6J3QSL4
uniprot id: A0A6J3QT14
uniprot id: A0A6J3QTL6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:KEG93 p05
gene id: 9739:KEG93_p05
uniprot id: B9UD84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Core subunit of respiratory chain NADH dehydrogenase (Complex I) which is composed of 45 different subunits.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
messages: Membrane
messages: Mitochondrion inner membrane

9739:IRAK1BP1
gene id: 9739:IRAK1BP1
uniprot id: A0A2U4AV96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRAK1BP1 family.
messages: Cytoplasm
messages: Nucleus

9739:LOC117312803
gene id: 9739:LOC117312803
uniprot id: A0A6J3RLG6
names: Similarity
messages: Belongs to the SPATA31 family.

9739:CERS1
gene id: 9739:CERS1
uniprot id: A0A6J3R636
names: Subcellular Location Annotation
messages: Membrane

9739:RAB33B
gene id: 9739:RAB33B
uniprot id: A0A2U4ARD9
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

9739:LOC101340139
gene id: 9739:LOC101340139
uniprot id: A0A6J3RK25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

9739:FZD3
gene id: 9739:FZD3
uniprot id: A0A2U4BUM2
uniprot id: A0A2U4BUM5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:GNPDA1
gene id: 9739:GNPDA1
uniprot id: A0A2U4AGR6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

9739:PDE1C
gene id: 9739:PDE1C
uniprot id: A0A2U4AKN4
uniprot id: A0A2U4AL38
uniprot id: A0A6J3RWT8
uniprot id: A0A6J3RWX6
uniprot id: A0A6J3RXG9
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9739:CPPED1
gene id: 9739:CPPED1
uniprot id: A0A6J3Q0B6
uniprot id: A0A6J3Q0B7
uniprot id: A0A6J3Q0H8
uniprot id: A0A6J3Q0V1
names: Function
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. CPPED1 family.
messages: Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. May play an inhibitory role in glucose uptake by adipocytes.

9739:LOC101338646
gene id: 9739:LOC101338646
uniprot id: A0A2U3V9V5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9739:GRP
gene id: 9739:GRP
uniprot id: A0A2U4BI05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bombesin/neuromedin-B/ranatensin family.
messages: Secreted
messages: neuron projection

9739:LOC101324316
gene id: 9739:LOC101324316
uniprot id: A0A2U4C510
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9739:MRGBP
gene id: 9739:MRGBP
uniprot id: A0A6J3Q041
uniprot id: A0A6J3Q0M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EAF7 family.
messages: Nucleus

9739:TM4SF19
gene id: 9739:TM4SF19
uniprot id: A0A6J3R9W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

9739:PWP2
gene id: 9739:PWP2
uniprot id: A0A6J3RC53
uniprot id: A0A6J3RDT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PWP2 family.
messages: nucleolus

9739:ACSL5
gene id: 9739:ACSL5
uniprot id: A0A2U4BQR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.
messages: Endoplasmic reticulum membrane
messages: Mitochondrion outer membrane

9739:NAPA
gene id: 9739:NAPA
uniprot id: A0A6J3QI59
uniprot id: A0A6J3QIQ4
uniprot id: A0A6J3QIT6
uniprot id: A0A6J3QJ83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

9739:COG7
gene id: 9739:COG7
uniprot id: A0A2U4A9B0
uniprot id: A0A6J3Q171
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG7 family.
messages: Golgi apparatus membrane
messages: Membrane

9739:LOC117312451
gene id: 9739:LOC117312451
uniprot id: A0A6J3RFA6
names: Similarity
messages: Belongs to the unc-5 family.

9739:SNX13
gene id: 9739:SNX13
uniprot id: A0A2U4AS96
uniprot id: A0A2U4AS97
uniprot id: A0A2U4ASA5
uniprot id: A0A6J3RWG8
names: Similarity
messages: Belongs to the sorting nexin family.

9739:LOC117312434
gene id: 9739:LOC117312434
uniprot id: A0A6J3REI6
uniprot id: A0A6J3REK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BOD1 family.
messages: centrosome
messages: kinetochore

9739:GAMT
gene id: 9739:GAMT
uniprot id: A0A6J3R7M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.
messages: Converts guanidinoacetate to creatine, using S-adenosylmethionine as the methyl donor.
messages: Monomer.

9739:UCHL5
gene id: 9739:UCHL5
uniprot id: A0A2U4A4R5
uniprot id: A0A2U4A4R7
uniprot id: A0A2U4A4S6
names: Similarity
messages: Belongs to the peptidase C12 family.

9739:ADGRF1
gene id: 9739:ADGRF1
uniprot id: A0A2U4CJB9
names: Subcellular Location Annotation
messages: Membrane

9739:LOC101323272
gene id: 9739:LOC101323272
uniprot id: A0A2U3V821
uniprot id: A0A2U4B694
uniprot id: A0A2U4B6A2
uniprot id: A0A2U4B6B7
uniprot id: A0A2U4B6F6
uniprot id: A0A2U4B6G1
uniprot id: A0A2U4B6P2
names: Similarity
messages: Belongs to the aldo/keto reductase family.

9739:PKD2
gene id: 9739:PKD2
uniprot id: A0A2U4ALW0
uniprot id: A0A2U4ALZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Cell membrane
messages: Membrane
messages: cilium membrane

9739:GGA3
gene id: 9739:GGA3
uniprot id: A0A6J3QM44
uniprot id: A0A6J3QMQ5
uniprot id: A0A6J3QN59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

9739:LOC101333723
gene id: 9739:LOC101333723
uniprot id: A0A2U3UZ63
uniprot id: A0A6J3RV11
uniprot id: A0A6J3RV15
uniprot id: A0A6J3RV19
uniprot id: A0A6J3RVH3
uniprot id: A0A6J3RVH9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:HPSE
gene id: 9739:HPSE
uniprot id: A0A2U3V8L1
uniprot id: A0A2U3V8L3
uniprot id: A0A2U3V8Z0
names: Similarity
messages: Belongs to the glycosyl hydrolase 79 family.

9739:RPS25
gene id: 9739:RPS25
uniprot id: A0A2U4BVW1
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS25 family.
messages: Component of the small ribosomal subunit.

9739:AOC3
gene id: 9739:AOC3
uniprot id: A0A6J3QP11
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

9739:SGO2
gene id: 9739:SGO2
uniprot id: A0A2U4BNF2
uniprot id: A0A2U4BNR6
uniprot id: A0A6J3RM76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

9739:USP48
gene id: 9739:USP48
uniprot id: A0A2U4BLN3
uniprot id: A0A2U4BLS7
uniprot id: A0A2U4BLZ8
uniprot id: A0A2U4BM03
uniprot id: A0A6J3Q5P8
uniprot id: A0A6J3Q626
uniprot id: A0A6J3Q689
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Nucleus

9739:ITGB1
gene id: 9739:ITGB1
uniprot id: A0A2U4B702
uniprot id: A0A6J3R2R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Melanosome
messages: Membrane
messages: Recycling endosome
messages: focal adhesion
messages: invadopodium membrane
messages: lamellipodium
messages: ruffle membrane

9739:C21H4orf47
gene id: 9739:C21H4orf47
uniprot id: A0A2U4A850
uniprot id: A0A6J3QQK4
uniprot id: A0A6J3QRC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP96 family.
messages: centrosome

9739:KCNA4
gene id: 9739:KCNA4
uniprot id: A0A6J3RVG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.4/KCNA4 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: axon

9739:VPS4A
gene id: 9739:VPS4A
uniprot id: A0A2U4BD72
uniprot id: A0A2U4BD75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

9739:URM1
gene id: 9739:URM1
uniprot id: A0A6J3RIQ8
uniprot id: A0A6J3RJ00
uniprot id: A0A6J3RJ04
uniprot id: A0A6J3RJ10
uniprot id: A0A6J3RJR9
uniprot id: A0A6J3RJS4
uniprot id: A0A6J3RKP9
uniprot id: A0A6J3RKQ3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as MOCS3, ATPBD3, CTU2, USP15 and CAS. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
messages: Belongs to the URM1 family.
messages: C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of MOCS3, then thiocarboxylated (-COSH) via the rhodanese domain of MOCS3.
messages: Component of a complex at least composed of URM1, CTU2/NCS2 and CTU1/ATPBD3.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:CTSF
gene id: 9739:CTSF
uniprot id: A0A6J3RR09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

9739:NME7
gene id: 9739:NME7
uniprot id: A0A2U4CS69
uniprot id: A0A2U4CSA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: cilium axoneme

9739:MRPL37
gene id: 9739:MRPL37
uniprot id: A0A2U4BJB3
names: Subcellular Location Annotation
messages: Mitochondrion

9739:PEX19
gene id: 9739:PEX19
uniprot id: A0A6J3RC12
uniprot id: A0A6J3RCT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxin-19 family.
messages: Interacts with a broad range of peroxisomal membrane proteins, including PEX3, PEX10, PEX11A, PEX11B, PEX12, PEX13, PEX14 and PEX16, PXMP2/PMP22, PXMP4/PMP24, SLC25A17/PMP34, ABCD1/ALDP, ABCD2/ALDRP, and ABCD3/PMP70. Also interacts with the tumor suppressor CDKN2A/p19ARF.
messages: Membrane
messages: Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53.
messages: Peroxisome membrane

9739:GALNT2
gene id: 9739:GALNT2
uniprot id: A0A6J3Q6T2
uniprot id: A0A6J3Q7M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9739:INTS9
gene id: 9739:INTS9
uniprot id: A0A2U4BUN2
uniprot id: A0A2U4BUN4
uniprot id: A0A2U4BUN9
uniprot id: A0A2U4BUT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS9 subfamily.
messages: Nucleus

9739:RPL26L1
gene id: 9739:RPL26L1
uniprot id: A0A2U3V143
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

9739:SLC1A2
gene id: 9739:SLC1A2
uniprot id: A0A6J3RP14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

9739:ATP5MF
gene id: 9739:ATP5MF
uniprot id: A0A2U3V2F9
uniprot id: A0A2U3V2T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase F chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

9739:FOXO3
gene id: 9739:FOXO3
uniprot id: A0A6J3S954
names: Subcellular Location Annotation
messages: Nucleus

9739:CBLIF
gene id: 9739:CBLIF
uniprot id: A0A2U4CF66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic cobalamin transport proteins family.
messages: Secreted

9739:PDPR
gene id: 9739:PDPR
uniprot id: A0A6J3QHV7
uniprot id: A0A6J3QHW2
uniprot id: A0A6J3QIH2
uniprot id: A0A6J3QIK2
uniprot id: A0A6J3QIY3
uniprot id: A0A6J3QIY9
names: Similarity
messages: Belongs to the GcvT family.

9739:TMEM181
gene id: 9739:TMEM181
uniprot id: A0A6J3SAA8
uniprot id: A0A6J3SB50
names: Subcellular Location Annotation
messages: Membrane

9739:LOC101326320
gene id: 9739:LOC101326320
uniprot id: A0A2U3VAA8
names: Similarity
messages: Belongs to the DMRT family.

9739:SEPTIN7
gene id: 9739:SEPTIN7
uniprot id: A0A2U4AJG0
uniprot id: A0A2U4AJH0
uniprot id: A0A2U4AJI1
uniprot id: A0A2U4AJM1
uniprot id: A0A2U4AJN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Filament-forming cytoskeletal GTPase.
messages: Midbody
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.
messages: cilium axoneme
messages: flagellum
messages: kinetochore
messages: spindle

9739:HTRA1
gene id: 9739:HTRA1
uniprot id: A0A2U4BR92
names: Similarity
messages: Belongs to the peptidase S1C family.

9739:HNRNPD
gene id: 9739:HNRNPD
uniprot id: A0A2U3V836
uniprot id: A0A2U3V853
uniprot id: A0A2U3V861
uniprot id: A0A2U3V8J6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9739:LOC101323101
gene id: 9739:LOC101323101
uniprot id: A0A6J3R9D5
names: Similarity
messages: Belongs to the TCTP family.

9739:DONSON
gene id: 9739:DONSON
uniprot id: A0A2U4AA41
uniprot id: A0A2U4AA71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DONSON family.
messages: Nucleus

9739:SNX19
gene id: 9739:SNX19
uniprot id: A0A6J3RST2
uniprot id: A0A6J3RST9
uniprot id: A0A6J3RT95
names: Similarity
messages: Belongs to the sorting nexin family.

9739:TMPO
gene id: 9739:TMPO
uniprot id: A0A2U3V4C0
uniprot id: A0A2U3V4D2
uniprot id: A0A2U4CS81
uniprot id: A0A2U4CSA3
names: Similarity
messages: Belongs to the LEM family.

9739:TMEM265
gene id: 9739:TMEM265
uniprot id: A0A6J3Q0K8
names: Similarity
messages: Belongs to the CD225/Dispanin family.

9739:GNG4
gene id: 9739:GNG4
uniprot id: A0A2U3V300
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

9739:CCDC90B
gene id: 9739:CCDC90B
uniprot id: A0A2U4CFQ1
uniprot id: A0A2U4CFU6
uniprot id: A0A6J3RU96
names: Similarity
messages: Belongs to the CCDC90 family.

9739:SNRPN
gene id: 9739:SNRPN
uniprot id: A0A2U4C7M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP SmB/SmN family.
messages: Nucleus

9739:TASP1
gene id: 9739:TASP1
uniprot id: A0A2U4BUU0
uniprot id: A0A2U4BUU7
uniprot id: A0A2U4BV01
uniprot id: A0A6J3PXW3
uniprot id: A0A6J3PXZ1
uniprot id: A0A6J3PXZ8
uniprot id: A0A6J3PY72
uniprot id: A0A6J3PYG9
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

9739:MAP7
gene id: 9739:MAP7
uniprot id: A0A2U4CP19
uniprot id: A0A2U4CP20
uniprot id: A0A2U4CP21
uniprot id: A0A2U4CP24
uniprot id: A0A2U4CPC2
names: Similarity
messages: Belongs to the MAP7 family.

9739:EIF4ENIF1
gene id: 9739:EIF4ENIF1
uniprot id: A0A2U4CJL3
uniprot id: A0A2U4CJL6
uniprot id: A0A2U4CJL7
uniprot id: A0A2U4CJM0
uniprot id: A0A2U4CJM3
uniprot id: A0A2U4CJU6
uniprot id: A0A6J3PSI7
names: Subcellular Location Annotation
messages: Cytoplasm

9739:GNG14
gene id: 9739:GNG14
uniprot id: A0A6J3R608
names: Similarity
messages: Belongs to the G protein gamma family.

9739:MARVELD1
gene id: 9739:MARVELD1
uniprot id: A0A2U4BQ89
names: Subcellular Location Annotation
messages: Membrane

9739:SPOUT1
gene id: 9739:SPOUT1
uniprot id: A0A6J3RIT3
uniprot id: A0A6J3RJ39
uniprot id: A0A6J3RJ45
uniprot id: A0A6J3RKU7
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily.

9739:ZSCAN23
gene id: 9739:ZSCAN23
uniprot id: A0A2U4C4Z5
names: Subcellular Location Annotation
messages: Nucleus

9739:P4HB
gene id: 9739:P4HB
uniprot id: A0A2U3UYG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

9739:ZACN
gene id: 9739:ZACN
uniprot id: A0A6J3QJD5
names: Subcellular Location Annotation
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9739:CRLS1
gene id: 9739:CRLS1
uniprot id: A0A2U4BUX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

9739:TMPRSS13
gene id: 9739:TMPRSS13
uniprot id: A0A6J3RTS6
uniprot id: A0A6J3RU52
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:SFXN2
gene id: 9739:SFXN2
uniprot id: A0A6J3Q6P7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

9739:LHX5
gene id: 9739:LHX5
uniprot id: A0A6J3PUG8
names: Subcellular Location Annotation
messages: Nucleus

9739:LOC101332449
gene id: 9739:LOC101332449
uniprot id: A0A2U4AJI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: nucleolus
messages: nucleoplasm

9739:RNF146
gene id: 9739:RNF146
uniprot id: A0A2U4CPM3
uniprot id: A0A2U4CPM4
names: Domain
names: Function
names: PTM
names: Subcellular Location Annotation
messages: E3 ubiquitin-protein ligase that specifically binds poly-ADP-ribosylated proteins and mediates their ubiquitination and subsequent degradation.
messages: The WWE domain mediates non-covalent poly(ADP-ribose)-binding.
messages: Ubiquitinated; autoubiquitinated.
messages: cytosol

9739:BET1
gene id: 9739:BET1
uniprot id: A0A6J3RWL7
names: Subcellular Location Annotation
messages: Membrane

9739:ITM2A
gene id: 9739:ITM2A
uniprot id: A0A2U3V5Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

9739:LOC117309411
gene id: 9739:LOC117309411
uniprot id: A0A6J3QKE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.
messages: Cell projection
messages: Mitochondrion membrane

9739:GCAT
gene id: 9739:GCAT
uniprot id: A0A2U3UZX2
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

9739:ARF5
gene id: 9739:ARF5
uniprot id: A0A2U3V7G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

9739:STEAP4
gene id: 9739:STEAP4
uniprot id: A0A2U3V7E5
uniprot id: A0A6J3RWT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

9739:MRPS25
gene id: 9739:MRPS25
uniprot id: A0A2U3VAL5
uniprot id: A0A2U4B7Q2
uniprot id: A0A2U4B7W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS25 family.
messages: Mitochondrion

9739:CRAT
gene id: 9739:CRAT
uniprot id: A0A6J3RJ56
uniprot id: A0A6J3RJZ0
uniprot id: A0A6J3RKW8
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

9739:BPNT1
gene id: 9739:BPNT1
uniprot id: A0A6J3QW35
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

9739:PRDX6
gene id: 9739:PRDX6
uniprot id: A0A2U4CQ37
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

9739:OPN5
gene id: 9739:OPN5
uniprot id: A0A2U3V1E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

9739:ETFB
gene id: 9739:ETFB
uniprot id: A0A6J3QH34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

9739:FTSJ1
gene id: 9739:FTSJ1
uniprot id: A0A2U4C0V4
uniprot id: A0A2U4C139
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.
messages: Cytoplasm
messages: Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.

9739:NFE2L1
gene id: 9739:NFE2L1
uniprot id: A0A2U3V910
uniprot id: A0A2U4AHP2
uniprot id: A0A2U4AHP7
uniprot id: A0A2U4AHY0
uniprot id: A0A6J3QNV9
uniprot id: A0A6J3QNZ2
uniprot id: A0A6J3QPF1
uniprot id: A0A6J3QPF5
uniprot id: A0A6J3QPQ4
uniprot id: A0A6J3QQ27
uniprot id: A0A6J3QQ31
names: Similarity
messages: Belongs to the bZIP family. CNC subfamily.

9739:MTERF4
gene id: 9739:MTERF4
uniprot id: A0A2U3V2X5
uniprot id: A0A2U4BBA8
names: Similarity
messages: Belongs to the mTERF family.

9739:ASCC3
gene id: 9739:ASCC3
uniprot id: A0A2U4AVQ2
uniprot id: A0A2U4AVR5
uniprot id: A0A2U4AVS8
uniprot id: A0A2U4AW71
names: Similarity
messages: Belongs to the helicase family.

9739:LOC117313780
gene id: 9739:LOC117313780
uniprot id: A0A6J3RYH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

9739:LOC101339985
gene id: 9739:LOC101339985
uniprot id: A0A2U4C2R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCO1/2 family.
messages: Mitochondrion inner membrane

9739:CGAS
gene id: 9739:CGAS
uniprot id: A0A2U4AV50
names: Similarity
messages: Belongs to the mab-21 family.

9739:NEURL2
gene id: 9739:NEURL2
uniprot id: A0A2U3V3R2
names: Subcellular Location Annotation
messages: Cytoplasm

9739:HOMER3
gene id: 9739:HOMER3
uniprot id: A0A6J3R5Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

9739:PDE1B
gene id: 9739:PDE1B
uniprot id: A0A6J3S601
uniprot id: A0A6J3S6G2
uniprot id: A0A6J3S7B1
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9739:KALRN
gene id: 9739:KALRN
uniprot id: A0A6J3RA22
uniprot id: A0A6J3RAI5
uniprot id: A0A6J3RCL7
uniprot id: A0A6J3RCM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cytoplasm

9739:ZC2HC1C
gene id: 9739:ZC2HC1C
uniprot id: A0A2U3V4G2
names: Similarity
messages: Belongs to the ZC2HC1 family.

9739:ELOVL3
gene id: 9739:ELOVL3
uniprot id: A0A2U3V3D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

9739:NME5
gene id: 9739:NME5
uniprot id: A0A2U4AGK9
names: Similarity
messages: Belongs to the NDK family.

9739:TBC1D7
gene id: 9739:TBC1D7
uniprot id: A0A2U4C532
uniprot id: A0A2U4C554
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Vesicle

9739:UBE2G2
gene id: 9739:UBE2G2
uniprot id: A0A2U4ABR5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9739:ADCK1
gene id: 9739:ADCK1
uniprot id: A0A6J3QVY2
uniprot id: A0A6J3QVY8
uniprot id: A0A6J3QW88
uniprot id: A0A6J3QWG5
uniprot id: A0A6J3QWH0
uniprot id: A0A6J3QWV5
uniprot id: A0A6J3QWW0
uniprot id: A0A6J3QXV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.
messages: Secreted

9739:DDX10
gene id: 9739:DDX10
uniprot id: A0A2U4BWB4
uniprot id: A0A2U4BWG8
uniprot id: A0A6J3RUA9
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

9739:LOC117309079
gene id: 9739:LOC117309079
uniprot id: A0A6J3QVJ7
names: Function
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.
messages: Metallothioneins have a high content of cysteine residues that bind various heavy metals.

9739:SPDEF
gene id: 9739:SPDEF
uniprot id: A0A6J3S081
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9739:LOC101328841
gene id: 9739:LOC101328841
uniprot id: A0A2U3VAT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

9739:NRF1
gene id: 9739:NRF1
uniprot id: A0A2U4AFE1
uniprot id: A0A2U4AFF1
uniprot id: A0A2U4AFG1
uniprot id: A0A2U4AFH5
uniprot id: A0A2U4AFW9
uniprot id: A0A2U4AFX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRF1/Ewg family.
messages: Nucleus

9739:SRRD
gene id: 9739:SRRD
uniprot id: A0A2U4CJW3
names: Similarity
messages: Belongs to the SRR1 family.

9739:OLA1
gene id: 9739:OLA1
uniprot id: A0A2U4AAY5
uniprot id: A0A6J3RM84
uniprot id: A0A6J3RMJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Cytoplasm
messages: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
messages: Monomer.
messages: Nucleus
messages: nucleolus

9739:LOC109550607
gene id: 9739:LOC109550607
uniprot id: A0A6J3QMU6
uniprot id: A0A6J3QN86
uniprot id: A0A6J3QND5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

9739:CA11
gene id: 9739:CA11
uniprot id: A0A6J3QEB4
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Does not have a catalytic activity.

9739:CACNG1
gene id: 9739:CACNG1
uniprot id: A0A2U4BM58
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either CACNB1 or CACNB2.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
messages: sarcolemma

9739:MID1IP1
gene id: 9739:MID1IP1
uniprot id: A0A2U3VAL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

9739:AOX1
gene id: 9739:AOX1
uniprot id: A0A2U4BNE4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Cytoplasm
messages: Homodimer.

9739:LOC101339762
gene id: 9739:LOC101339762
uniprot id: A0A6J3QYC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DUOXA family.
messages: Membrane

9739:PTX4
gene id: 9739:PTX4
uniprot id: A0A6J3Q1K6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:PLPPR4
gene id: 9739:PLPPR4
uniprot id: A0A2U3V9L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

9739:DCC
gene id: 9739:DCC
uniprot id: A0A2U4BHD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. DCC family.
messages: Membrane

9739:LIMK1
gene id: 9739:LIMK1
uniprot id: A0A6J3Q3A6
uniprot id: A0A6J3Q3G6
uniprot id: A0A6J3Q3W3
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

9739:SPNS3
gene id: 9739:SPNS3
uniprot id: A0A6J3QM38
uniprot id: A0A6J3QM62
uniprot id: A0A6J3QML6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

9739:ALDOB
gene id: 9739:ALDOB
uniprot id: A0A6J3RKF8
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

9739:C6H9orf116
gene id: 9739:C6H9orf116
uniprot id: A0A2U3V6V7
uniprot id: A0A6J3RKH4
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with CFAP53, ODAD1 and ODAD3; the interactions link the outer dynein arms docking complex (ODA-DC) to the internal microtubule inner proteins (MIP) in cilium axoneme.
messages: cilium axoneme

9739:MCTP2
gene id: 9739:MCTP2
uniprot id: A0A2U4C7H6
uniprot id: A0A2U4C7I2
uniprot id: A0A2U4C7I8
uniprot id: A0A2U4C7S1
uniprot id: A0A6J3R1P3
names: Subcellular Location Annotation
messages: Membrane

9739:PIGC
gene id: 9739:PIGC
uniprot id: A0A2U3V245
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGC family.
messages: Membrane

9739:LOC117311152
gene id: 9739:LOC117311152
uniprot id: A0A6J3R0L9
uniprot id: A0A6J3R123
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

9739:LOC101333617
gene id: 9739:LOC101333617
uniprot id: A0A6J3QU88
names: Similarity
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.

9739:PIGN
gene id: 9739:PIGN
uniprot id: A0A2U4BHN1
uniprot id: A0A2U4BHN7
uniprot id: A0A2U4BHT1
uniprot id: A0A2U4BI20
uniprot id: A0A2U4BI26
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.
messages: Endoplasmic reticulum membrane
messages: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:BAZ2A
gene id: 9739:BAZ2A
uniprot id: A0A2U4CQG1
uniprot id: A0A6J3S5Z5
uniprot id: A0A6J3S5Z9
uniprot id: A0A6J3S668
uniprot id: A0A6J3S726
uniprot id: A0A6J3S7D7
names: Similarity
messages: Belongs to the WAL family.

9739:PIAS2
gene id: 9739:PIAS2
uniprot id: A0A2U4BH61
uniprot id: A0A2U4BH62
uniprot id: A0A2U4BH65
uniprot id: A0A2U4BH67
uniprot id: A0A2U4BH75
uniprot id: A0A2U4BHK7
uniprot id: A0A6J3PUE5
names: Similarity
messages: Belongs to the PIAS family.

9739:PIGK
gene id: 9739:PIGK
uniprot id: A0A2U4A3J6
names: Similarity
names: Subunit
messages: Belongs to the peptidase C13 family.
messages: Forms a complex with PIGT, PIGS, PIGU and GAA1.

9739:NDUFC1
gene id: 9739:NDUFC1
uniprot id: A0A2U4ARE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFC1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9739:ATP6V1G1
gene id: 9739:ATP6V1G1
uniprot id: A0A2U4C9C6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

9739:NDFIP1
gene id: 9739:NDFIP1
uniprot id: A0A2U4AGS8
uniprot id: A0A2U4AH84
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

9739:DNASE1L3
gene id: 9739:DNASE1L3
uniprot id: A0A2U4CCW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNase I family.
messages: Nucleus envelope
messages: Zymogen granule

9739:LAMP2
gene id: 9739:LAMP2
uniprot id: A0A2U4CHV1
uniprot id: A0A2U4CHV3
uniprot id: A0A2U4CHV5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lysosome membrane
messages: Membrane

9739:SNX10
gene id: 9739:SNX10
uniprot id: A0A2U4AM83
uniprot id: A0A6J3RWQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

9739:MEOX1
gene id: 9739:MEOX1
uniprot id: A0A2U3V515
uniprot id: A0A2U4BPD9
names: Subcellular Location Annotation
messages: Nucleus

9739:WDR91
gene id: 9739:WDR91
uniprot id: A0A2U3V733
uniprot id: A0A2U4CQV9
uniprot id: A0A2U4CQZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR91 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

9739:LOC117310000
gene id: 9739:LOC117310000
uniprot id: A0A6J3QQK6
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS25 family.
messages: Component of the small ribosomal subunit.

9739:SERPINE1
gene id: 9739:SERPINE1
uniprot id: A0A6J3Q1Z5
names: Similarity
messages: Belongs to the serpin family.

9739:AGT
gene id: 9739:AGT
uniprot id: A0A2U4BVC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the serpin family.
messages: Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis.
messages: Secreted
messages: Stimulates aldosterone release.

9739:PIGV
gene id: 9739:PIGV
uniprot id: A0A2U4BL58
uniprot id: A0A2U4BLJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGV family.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.
messages: Membrane

9739:MMGT1
gene id: 9739:MMGT1
uniprot id: A0A2U3V5C6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane magnesium transporter (TC 1.A.67) family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. May be involved in Mg(2+) transport.

9739:E2F2
gene id: 9739:E2F2
uniprot id: A0A6J3Q4N8
uniprot id: A0A6J3Q4P1
uniprot id: A0A6J3Q4P6
uniprot id: A0A6J3Q557
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

9739:PCNT
gene id: 9739:PCNT
uniprot id: A0A6J3RBF9
uniprot id: A0A6J3RBG4
uniprot id: A0A6J3RBN4
uniprot id: A0A6J3RBN9
uniprot id: A0A6J3RC74
uniprot id: A0A6J3RC80
uniprot id: A0A6J3RCF1
uniprot id: A0A6J3RE29
names: Subcellular Location Annotation
messages: centrosome

9739:CETN2
gene id: 9739:CETN2
uniprot id: A0A2U3V7Q7
names: Similarity
messages: Belongs to the centrin family.

9739:LOC101331068
gene id: 9739:LOC101331068
uniprot id: A0A2U4C4W8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9739:CTH
gene id: 9739:CTH
uniprot id: A0A2U3V8T7
uniprot id: A0A2U3V8V6
uniprot id: A0A2U3V8W5
uniprot id: A0A2U4A3G9
uniprot id: A0A2U4A3I5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

9739:KIDINS220
gene id: 9739:KIDINS220
uniprot id: A0A2U4C088
uniprot id: A0A2U4C0D5
uniprot id: A0A6J3PV11
uniprot id: A0A6J3PVC7
uniprot id: A0A6J3PVS8
names: Function
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

9739:RB1
gene id: 9739:RB1
uniprot id: A0A2U4BGD6
uniprot id: A0A6J3QAU1
uniprot id: A0A6J3QBC9
uniprot id: A0A6J3QBM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

9739:DBT
gene id: 9739:DBT
uniprot id: A0A2U3V1F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Mitochondrion matrix

9739:B2M
gene id: 9739:B2M
uniprot id: A0A6J3R080
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-2-microglobulin family.
messages: Secreted

9739:KATNAL2
gene id: 9739:KATNAL2
uniprot id: A0A2U4BHL3
uniprot id: A0A6J3PTW4
uniprot id: A0A6J3PU14
uniprot id: A0A6J3PUG0
uniprot id: A0A6J3PUW1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 2 sub-subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.
messages: cytoskeleton
messages: spindle
messages: spindle pole

9739:ITGB2
gene id: 9739:ITGB2
uniprot id: D7NN73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane
messages: Membrane raft

9739:ZNF830
gene id: 9739:ZNF830
uniprot id: A0A2U3V2C0
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus speckle

9739:LOC117313303
gene id: 9739:LOC117313303
uniprot id: A0A2U3V7P0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

9739:LOC101315581
gene id: 9739:LOC101315581
uniprot id: A0A2U3VA15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

9739:SCNN1A
gene id: 9739:SCNN1A
uniprot id: A0A6J3S7K4
names: Subcellular Location Annotation
messages: Membrane

9739:CTSL
gene id: 9739:CTSL
uniprot id: A0A2U3V4W6
uniprot id: A0A2U4BRX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

9739:LOC101316317
gene id: 9739:LOC101316317
uniprot id: A0A2U4CJW1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:ACTL6B
gene id: 9739:ACTL6B
uniprot id: A0A2U4C6M4
names: Similarity
messages: Belongs to the actin family.

9739:MANEAL
gene id: 9739:MANEAL
uniprot id: A0A2U4BKA6
uniprot id: A0A6J3PUK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

9739:C15H16orf91
gene id: 9739:C15H16orf91
uniprot id: A0A2U3UYZ4
names: Similarity
messages: Belongs to the UQCC4 family.

9739:PGD
gene id: 9739:PGD
uniprot id: A0A2U4AZR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

9739:AP4B1
gene id: 9739:AP4B1
uniprot id: A0A6J3RSD0
uniprot id: A0A6J3RSR4
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

9739:NDUFS1
gene id: 9739:NDUFS1
uniprot id: A0A2U4BN32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 75 kDa subunit family.
messages: Mitochondrion inner membrane

9739:OXSM
gene id: 9739:OXSM
uniprot id: A0A2U3V1F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function.
messages: Mitochondrion

9739:AGAP1
gene id: 9739:AGAP1
uniprot id: A0A6J3RKQ8
uniprot id: A0A6J3RL45
uniprot id: A0A6J3RL50
uniprot id: A0A6J3RL52
uniprot id: A0A6J3RL57
uniprot id: A0A6J3RLZ1
uniprot id: A0A6J3RLZ6
uniprot id: A0A6J3RMJ0
uniprot id: A0A6J3RMJ2
names: Similarity
messages: Belongs to the centaurin gamma-like family.

9739:PPIL2
gene id: 9739:PPIL2
uniprot id: A0A6J3PTE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.
messages: Nucleus

9739:FOXJ1
gene id: 9739:FOXJ1
uniprot id: A0A6J3QMV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FOXJ1 family.
messages: Nucleus

9739:IRF5
gene id: 9739:IRF5
uniprot id: A0A6J3RX36
uniprot id: A0A6J3RX91
uniprot id: A0A6J3RX92
names: Subcellular Location Annotation
messages: Nucleus

9739:TFF2
gene id: 9739:TFF2
uniprot id: A0A6J3REC1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:LOC101337846
gene id: 9739:LOC101337846
uniprot id: A0A6J3QMB6
names: Similarity
messages: Belongs to the intermediate filament family.

9739:AFM
gene id: 9739:AFM
uniprot id: A0A2U3V609
names: Subcellular Location Annotation
messages: Secreted

9739:DKK1
gene id: 9739:DKK1
uniprot id: A0A2U3V7E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

9739:GUK1
gene id: 9739:GUK1
uniprot id: A0A6J3R476
uniprot id: A0A6J3R4F7
uniprot id: A0A6J3R4W3
uniprot id: A0A6J3R566
uniprot id: A0A6J3R6N2
names: Similarity
messages: Belongs to the guanylate kinase family.

9739:LOXL1
gene id: 9739:LOXL1
uniprot id: A0A2U3V079
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

9739:DNAJA2
gene id: 9739:DNAJA2
uniprot id: A0A2U4B474
uniprot id: A0A2U4B4M2
names: Subcellular Location Annotation
messages: Membrane

9739:SDC1
gene id: 9739:SDC1
uniprot id: A0A6J3PVJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

9739:CCS
gene id: 9739:CCS
uniprot id: A0A2U4BIR1
names: Similarity
messages: In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family.

9739:LOC117311594
gene id: 9739:LOC117311594
uniprot id: A0A6J3R2Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.
messages: Catalyzes viral DNA integration into the host chromosome, by performing a series of DNA cutting and joining reactions. This enzyme activity takes place after virion entry into a cell and reverse transcription of the RNA genome in dsDNA. The first step in the integration process is 3' processing. This step requires a complex comprising the viral genome, matrix protein and integrase. This complex is called the pre-integration complex (PIC). The integrase protein removes 2 nucleotides from each 3' end of the viral DNA, leaving recessed CA OH's at the 3' ends. In the second step that requires cell division, the PIC enters cell nucleus. In the third step, termed strand transfer, the integrase protein joins the previously processed 3' ends to the 5' ends of strands of target cellular DNA at the site of integration. The last step is viral DNA integration into host chromosome.
messages: Forms the spherical core of the virion that encapsulates the genomic RNA-nucleocapsid complex.
messages: Virion

9739:LOC101322568
gene id: 9739:LOC101322568
uniprot id: A0A2U3V3V4
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

9739:CNN1
gene id: 9739:CNN1
uniprot id: A0A6J3R6M9
uniprot id: A0A6J3R8D9
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

9739:CLCF1
gene id: 9739:CLCF1
uniprot id: A0A6J3RR20
uniprot id: A0A6J3RR98
uniprot id: A0A6J3RRW9
uniprot id: A0A6J3RRY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

9739:XPO4
gene id: 9739:XPO4
uniprot id: A0A2U4BGX2
uniprot id: A0A2U4BGX3
uniprot id: A0A2U4BGX8
uniprot id: A0A2U4BGX9
uniprot id: A0A2U4BHB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Nucleus

9739:DIPK2B
gene id: 9739:DIPK2B
uniprot id: A0A6J3QT98
uniprot id: A0A6J3QTU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Secreted

9739:ADAMTS18
gene id: 9739:ADAMTS18
uniprot id: A0A2U4BT67
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9739:SLC12A5
gene id: 9739:SLC12A5
uniprot id: A0A6J3PYY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

9739:YME1L1
gene id: 9739:YME1L1
uniprot id: A0A2U3V7H5
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

9739:TMEM237
gene id: 9739:TMEM237
uniprot id: A0A2U4BN94
uniprot id: A0A2U4BNE6
uniprot id: A0A2U4BNK6
uniprot id: A0A6J3RLT5
uniprot id: A0A6J3RM64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM237 family.
messages: Component of the transition zone in primary cilia. Required for ciliogenesis.
messages: Membrane
messages: cilium

9739:AASS
gene id: 9739:AASS
uniprot id: A0A2U4AH22
uniprot id: A0A6J3RWY2
uniprot id: A0A6J3RX35
names: Similarity
messages: In the C-terminal section; belongs to the saccharopine dehydrogenase family.
messages: In the N-terminal section; belongs to the AlaDH/PNT family.

9739:ORC6
gene id: 9739:ORC6
uniprot id: A0A2U3VAC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC6 family.
messages: Nucleus

9739:XPO5
gene id: 9739:XPO5
uniprot id: A0A2U4CIK2
uniprot id: A0A2U4CIK5
uniprot id: A0A2U4CIL1
uniprot id: A0A2U4CIM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm

9739:SLC7A8
gene id: 9739:SLC7A8
uniprot id: A0A6J3QXI7
uniprot id: A0A6J3QXV8
uniprot id: A0A6J3QY03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Cell membrane
messages: Membrane

9739:ANAPC11
gene id: 9739:ANAPC11
uniprot id: A0A2U4BSS2
names: Similarity
messages: Belongs to the RING-box family.

9739:LOC109552729
gene id: 9739:LOC109552729
uniprot id: A0A6J3R4C7
uniprot id: A0A6J3R5A8
names: Similarity
messages: Belongs to the MHC class I family.

9739:PTCD2
gene id: 9739:PTCD2
uniprot id: A0A6J3R2L1
uniprot id: A0A6J3R496
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTCD2 family.
messages: Mitochondrion

9739:NME2
gene id: 9739:NME2
uniprot id: A0A6J3QLC9
names: Similarity
messages: Belongs to the NDK family.

9739:LOC117312426
gene id: 9739:LOC117312426
uniprot id: A0A6J3RF26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: nucleolus
messages: nucleoplasm

9739:FAM216B
gene id: 9739:FAM216B
uniprot id: A0A2U3V967
names: Similarity
messages: Belongs to the FAM216 family.

9739:TSPAN1
gene id: 9739:TSPAN1
uniprot id: A0A6J3S848
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9739:TRH
gene id: 9739:TRH
uniprot id: A0A2U3V0B4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRH family.
messages: Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
messages: Secreted

9739:TCEA3
gene id: 9739:TCEA3
uniprot id: A0A6J3Q5K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

9739:LOC101328929
gene id: 9739:LOC101328929
uniprot id: A0A6J3Q189
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: myofibril

9739:OOEP
gene id: 9739:OOEP
uniprot id: A0A2U3V9L0
names: Similarity
messages: Belongs to the KHDC1 family.

9739:LOC117313626
gene id: 9739:LOC117313626
uniprot id: A0A6J3Q520
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TET family.
messages: Nucleus

9739:TADA3
gene id: 9739:TADA3
uniprot id: A0A2U4C434
uniprot id: A0A6J3S3W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGG1 family.
messages: Nucleus

9739:CARTPT
gene id: 9739:CARTPT
uniprot id: A0A2U4AUZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

9739:LOC117313776
gene id: 9739:LOC117313776
uniprot id: A0A6J3RZF6
names: Similarity
messages: Belongs to the serpin family.

9739:NSUN5
gene id: 9739:NSUN5
uniprot id: A0A2U4A911
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

9739:TGFB2
gene id: 9739:TGFB2
uniprot id: A0A2U3V1D1
uniprot id: A0A2U3V1G6
uniprot id: A0A6J3QW85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.
messages: extracellular matrix

9739:DNAJC2
gene id: 9739:DNAJC2
uniprot id: A0A2U4BSA1
uniprot id: A0A2U4BSB5
uniprot id: A0A2U4BSM0
names: Function
names: Subcellular Location Annotation
messages: Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain. When nuclear, mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at 'Lys-119' (H2AK119ub), and promotes the displacement of the polycomb PRC1 complex from chromatin, thereby facilitating transcription activation.
messages: cytosol

9739:TCP11L1
gene id: 9739:TCP11L1
uniprot id: A0A2U3V1S9
uniprot id: A0A2U4CDU7
uniprot id: A0A2U4CDU9
uniprot id: A0A2U4CDV1
uniprot id: A0A2U4CDX0
names: Similarity
messages: Belongs to the TCP11 family.

9739:LOC101336783
gene id: 9739:LOC101336783
uniprot id: A0A2U4BKF6
uniprot id: A0A2U4BKJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argonaute family. Ago subfamily.
messages: Interacts with EIF4B, IMP8, PRMT5, TNRC6A and TNRC6B. Interacts with ZFP36.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.

9739:AMPD2
gene id: 9739:AMPD2
uniprot id: A0A6J3RU92
uniprot id: A0A6J3RUI9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

9739:EREG
gene id: 9739:EREG
uniprot id: A0A2U4B4Y9
uniprot id: A0A2U4B531
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:LOC101332105
gene id: 9739:LOC101332105
uniprot id: A0A2U4CHS6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

9739:METTL2A
gene id: 9739:METTL2A
uniprot id: A0A2U3UZB6
uniprot id: A0A2U4C3N6
uniprot id: A0A2U4C3N8
uniprot id: A0A2U4C3R6
uniprot id: A0A2U4C3S3
uniprot id: A0A2U4C3V4
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

9739:CASD1
gene id: 9739:CASD1
uniprot id: A0A2U4AQ68
uniprot id: A0A2U4AQ82
uniprot id: A0A6J3RX87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PC-esterase family. CASD1 subfamily.
messages: Membrane

9739:TJAP1
gene id: 9739:TJAP1
uniprot id: A0A6J3RZN4
uniprot id: A0A6J3S040
names: Subcellular Location Annotation
messages: Membrane

9739:SARM1
gene id: 9739:SARM1
uniprot id: A0A2U4ANS2
uniprot id: A0A2U4AP59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SARM1 family.
messages: axon

9739:ERLEC1
gene id: 9739:ERLEC1
uniprot id: A0A2U4BYA3
uniprot id: A0A2U4BYB3
uniprot id: A0A2U4BYE3
uniprot id: A0A2U4BYE8
uniprot id: A0A2U4BYG1
uniprot id: A0A2U4BYG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OS-9 family.
messages: Endoplasmic reticulum lumen
messages: Lectin involved in the quality control of the secretory pathway. As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, targets misfolded endoplasmic reticulum lumenal glycoproteins for degradation.

9739:MAP4K1
gene id: 9739:MAP4K1
uniprot id: A0A6J3QFW5
uniprot id: A0A6J3QGH9
uniprot id: A0A6J3QH00
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

9739:CD247
gene id: 9739:CD247
uniprot id: A0A6J3RAE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD3Z/FCER1G family.
messages: Cell membrane
messages: Membrane

9739:TEKT3
gene id: 9739:TEKT3
uniprot id: A0A6J3QMC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

9739:BEST4
gene id: 9739:BEST4
uniprot id: A0A2U4BJU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.
messages: Cell membrane
messages: Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
messages: Membrane

9739:CHMP7
gene id: 9739:CHMP7
uniprot id: A0A2U3V5E6
names: Similarity
messages: Belongs to the SNF7 family.

9739:TPH2
gene id: 9739:TPH2
uniprot id: A0A2U3V2U2
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

9739:ELOVL4
gene id: 9739:ELOVL4
uniprot id: A0A2U4AVA7
uniprot id: A0A2U4AVD0
uniprot id: A0A2U4AVQ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ELO family.
messages: Belongs to the ELO family. ELOVL4 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May play a critical role in early brain and skin development.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Oligomer.
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

9739:PPIL3
gene id: 9739:PPIL3
uniprot id: A0A2U3V0M6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

9739:RAD23B
gene id: 9739:RAD23B
uniprot id: A0A2U4CGJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

9739:DENND11
gene id: 9739:DENND11
uniprot id: A0A6J3RXG8
uniprot id: A0A6J3RXL0
uniprot id: A0A6J3RXN3
uniprot id: A0A6J3RYA8
names: Similarity
messages: Belongs to the DENND11 family.

9739:RAB3D
gene id: 9739:RAB3D
uniprot id: A0A6J3R5V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

9739:LPGAT1
gene id: 9739:LPGAT1
uniprot id: A0A2U4CS53
uniprot id: A0A2U4CS57
uniprot id: A0A2U4CSA4
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

9739:MDK
gene id: 9739:MDK
uniprot id: A0A6J3RPJ0
uniprot id: A0A6J3RQ84
names: Similarity
messages: Belongs to the pleiotrophin family.

9739:CDT1
gene id: 9739:CDT1
uniprot id: A0A2U4ADG8
names: Similarity
messages: Belongs to the Cdt1 family.

9739:PTN
gene id: 9739:PTN
uniprot id: A0A2U4CK75
uniprot id: A0A2U4CKE7
names: Similarity
messages: Belongs to the pleiotrophin family.

9739:PGM3
gene id: 9739:PGM3
uniprot id: A0A2U4AVD9
uniprot id: A0A2U4AVF9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O-glycosylation.

9739:CLPTM1L
gene id: 9739:CLPTM1L
uniprot id: A0A2U3V3R7
uniprot id: A0A2U4CMI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

9739:THAP1
gene id: 9739:THAP1
uniprot id: A0A2U3V8C4
uniprot id: A0A2U4A768
uniprot id: A0A2U4A774
uniprot id: A0A2U4A801
uniprot id: A0A2U4A807
uniprot id: A0A6J3QQH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the THAP1 family.
messages: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes.
messages: Interacts with PAWR. Component of a THAP1/THAP3-HCFC1-OGT complex that contains, either THAP1 or THAP3, HCFC1 and OGT. Interacts with OGT. Interacts (via the HBM) with HCFC1 (via the Kelch-repeat domain); the interaction recruits HCFC1 to the RRM1 promoter.
messages: nucleoplasm

9739:SLC24A5
gene id: 9739:SLC24A5
uniprot id: A0A2U3V4I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

9739:GALT
gene id: 9739:GALT
uniprot id: A0A2U3V063
uniprot id: A0A2U4BRR3
uniprot id: A0A2U4BS10
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.

9739:FAM53B
gene id: 9739:FAM53B
uniprot id: A0A2U3V1I8
names: Similarity
messages: Belongs to the FAM53 family.

9739:NASP
gene id: 9739:NASP
uniprot id: A0A2U4BJN0
uniprot id: A0A2U4BJV1
uniprot id: A0A2U4BK28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NASP family.
messages: Nucleus

9739:LOC109548802
gene id: 9739:LOC109548802
uniprot id: A0A6J3RWJ1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

9739:SH3BP4
gene id: 9739:SH3BP4
uniprot id: A0A6J3RKR7
names: Subcellular Location Annotation
messages: Nucleus
messages: Vesicle
messages: clathrin-coated pit
messages: clathrin-coated vesicle

9739:KIF2C
gene id: 9739:KIF2C
uniprot id: A0A2U3V8Y0
uniprot id: A0A2U3V8Z3
uniprot id: A0A2U4BJY9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9739:CHN1
gene id: 9739:CHN1
uniprot id: A0A2U4AAZ6
names: Function
messages: GTPase-activating protein for p21-rac.

9739:HS3ST3A1
gene id: 9739:HS3ST3A1
uniprot id: A0A2U4C2S2
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9739:MIDN
gene id: 9739:MIDN
uniprot id: A0A6J3R7N6
uniprot id: A0A6J3R7T7
uniprot id: A0A6J3R884
uniprot id: A0A6J3R8R5
names: Subcellular Location Annotation
messages: Nucleus

9739:IFNK
gene id: 9739:IFNK
uniprot id: A0A6J3RGT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

9739:LOC117314510
gene id: 9739:LOC117314510
uniprot id: A0A6J3S9S7
names: Subcellular Location Annotation
messages: Nucleus

9739:G6PD
gene id: 9739:G6PD
uniprot id: A0A2U3V3X8
uniprot id: A0A6J3QTK9
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.

9739:CSAD
gene id: 9739:CSAD
uniprot id: A0A6J3S670
uniprot id: A0A6J3S7W6
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

9739:LOC101332563
gene id: 9739:LOC101332563
uniprot id: A0A6J3R9B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF12 family.
messages: Nucleus

9739:ATAD1
gene id: 9739:ATAD1
uniprot id: A0A2U3V1H5
names: Similarity
messages: Belongs to the AAA ATPase family.

9739:ABCC9
gene id: 9739:ABCC9
uniprot id: A0A2U4BG00
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with KCNJ11.
messages: Membrane

9739:TPP1
gene id: 9739:TPP1
uniprot id: A0A2U3V8L0
names: Cofactor
messages: Binds 1 Ca(2+) ion per subunit.

9739:SLC6A8
gene id: 9739:SLC6A8
uniprot id: A0A6J3QS78
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A8 subfamily.
messages: Cell membrane
messages: Membrane

9739:SLC41A3
gene id: 9739:SLC41A3
uniprot id: A0A6J3S3N4
uniprot id: A0A6J3S3N7
uniprot id: A0A6J3S3S7
uniprot id: A0A6J3S4G3
uniprot id: A0A6J3S4G9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:CNMD
gene id: 9739:CNMD
uniprot id: A0A2U3V0X2
uniprot id: A0A2U4BG15
names: Similarity
messages: Belongs to the chondromodulin-1 family.

9739:KEG93 p02
gene id: 9739:KEG93_p02
uniprot id: B9UD87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Core subunit of respiratory chain NADH dehydrogenase (Complex I) which is composed of 45 different subunits.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion membrane

9739:PLXND1
gene id: 9739:PLXND1
uniprot id: A0A6J3S367
uniprot id: A0A6J3S446
names: Caution
names: Similarity
messages: Belongs to the plexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:LOC109549814
gene id: 9739:LOC109549814
uniprot id: A0A6J3RBL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL15 family.
messages: Cytoplasm

9739:DNAH2
gene id: 9739:DNAH2
uniprot id: A0A6J3QQV1
names: Similarity
messages: Belongs to the dynein heavy chain family.

9739:SENP7
gene id: 9739:SENP7
uniprot id: A0A2U4AC70
uniprot id: A0A6J3RA76
uniprot id: A0A6J3RA82
uniprot id: A0A6J3RAH1
uniprot id: A0A6J3RAH5
uniprot id: A0A6J3RAX8
uniprot id: A0A6J3RBA1
uniprot id: A0A6J3RD06
names: Similarity
messages: Belongs to the peptidase C48 family.

9739:KCNJ11
gene id: 9739:KCNJ11
uniprot id: A0A2U3V3F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ11 subfamily.
messages: Membrane

9739:NR2C2
gene id: 9739:NR2C2
uniprot id: A0A6J3S368
uniprot id: A0A6J3S3D2
uniprot id: A0A6J3S451
uniprot id: A0A6J3S4D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9739:EXTL3
gene id: 9739:EXTL3
uniprot id: A0A2U4BUT2
uniprot id: A0A6J3RFX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:COPS7B
gene id: 9739:COPS7B
uniprot id: A0A2U4ADU9
uniprot id: A0A2U4ADX7
uniprot id: A0A2U4AE42
uniprot id: A0A6J3RKW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
messages: Cytoplasm
messages: Nucleus

9739:ADAM10
gene id: 9739:ADAM10
uniprot id: A0A2U4CBD7
uniprot id: A0A6J3QZ01
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:CHD2
gene id: 9739:CHD2
uniprot id: A0A2U4C6X5
uniprot id: A0A2U4C6Y4
uniprot id: A0A2U4C6Z4
uniprot id: A0A6J3QZQ1
uniprot id: A0A6J3R007
names: Subcellular Location Annotation
messages: Nucleus

9739:LACC1
gene id: 9739:LACC1
uniprot id: A0A2U3V841
uniprot id: A0A2U4BFS0
uniprot id: A0A6J3QB32
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

9739:SKI
gene id: 9739:SKI
uniprot id: A0A6J3Q4H5
names: Similarity
messages: Belongs to the SKI family.

9739:SS18
gene id: 9739:SS18
uniprot id: A0A2U3UYY1
uniprot id: A0A2U3UZA9
uniprot id: A0A2U4AYJ7
uniprot id: A0A2U4AYM0
uniprot id: A0A6J3PTM4
names: Similarity
messages: Belongs to the SS18 family.

9739:PAX6
gene id: 9739:PAX6
uniprot id: A0A6J3RVG5
uniprot id: A0A6J3RVK6
uniprot id: A0A6J3RVL0
uniprot id: A0A6J3RW28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

9739:MYO19
gene id: 9739:MYO19
uniprot id: A0A2U4C652
uniprot id: A0A2U4C659
uniprot id: A0A2U4C664
uniprot id: A0A2U4C667
uniprot id: A0A2U4C6E5
uniprot id: A0A6J3QQ90
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

9739:CLDN18
gene id: 9739:CLDN18
uniprot id: A0A2U4B8X4
uniprot id: A0A2U4B934
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

9739:KCNK5
gene id: 9739:KCNK5
uniprot id: A0A2U4CJ59
uniprot id: A0A2U4CJ65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

9739:ATP10D
gene id: 9739:ATP10D
uniprot id: A0A2U4AS45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

9739:REEP5
gene id: 9739:REEP5
uniprot id: A0A2U4BT45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

9739:SSH1
gene id: 9739:SSH1
uniprot id: A0A6J3PS35
uniprot id: A0A6J3PS80
uniprot id: A0A6J3PSM7
uniprot id: A0A6J3PSN4
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

9739:MAN2B1
gene id: 9739:MAN2B1
uniprot id: A0A6J3R5X2
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

9739:GINS2
gene id: 9739:GINS2
uniprot id: A0A2U4BC66
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS2/PSF2 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus

9739:SMC1B
gene id: 9739:SMC1B
uniprot id: A0A2U4C3X3
uniprot id: A0A2U4C420
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Chromosome
messages: Nucleus

9739:SNRPA1
gene id: 9739:SNRPA1
uniprot id: A0A2U3UZZ7
uniprot id: A0A2U4C7N9
uniprot id: A0A2U4C7P0
uniprot id: A0A2U4C7Y0
names: Similarity
messages: Belongs to the U2 small nuclear ribonucleoprotein A family.

9739:LOC101333550
gene id: 9739:LOC101333550
uniprot id: A0A6J3Q6Z3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

9739:TMEM11
gene id: 9739:TMEM11
uniprot id: A0A2U4AU82
uniprot id: A0A6J3QQJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM11 family.
messages: Membrane
messages: Plays a role in mitochondrial morphogenesis.

9739:SYCP2
gene id: 9739:SYCP2
uniprot id: A0A6J3Q3I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYCP2 family.
messages: Nucleus

9739:LOC101329303
gene id: 9739:LOC101329303
uniprot id: A0A6J3R8U1
names: Function
names: Similarity
messages: Belongs to the sorting nexin family.
messages: Involved in several stages of intracellular trafficking.

9739:ELK3
gene id: 9739:ELK3
uniprot id: A0A6J3S579
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9739:CAPN14
gene id: 9739:CAPN14
uniprot id: A0A6J3PVH2
names: Caution
names: Similarity
messages: Belongs to the peptidase C2 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:RHBDL2
gene id: 9739:RHBDL2
uniprot id: A0A6J3PTP3
uniprot id: A0A6J3PTV5
uniprot id: A0A6J3PU92
uniprot id: A0A6J3PUR5
uniprot id: A0A6J3PUR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Membrane

9739:CLDN25
gene id: 9739:CLDN25
uniprot id: A0A2U3VAF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

9739:RIOX1
gene id: 9739:RIOX1
uniprot id: A0A6J3QYA0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROX family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Nucleus
messages: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.

9739:STAR
gene id: 9739:STAR
uniprot id: A0A6J3QRX0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: May interact with TSPO.
messages: Mitochondrion
messages: Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.

9739:LOC101326854
gene id: 9739:LOC101326854
uniprot id: A0A6J3QNQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

9739:MUC5B
gene id: 9739:MUC5B
uniprot id: A0A6J3RTE0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:FAM161A
gene id: 9739:FAM161A
uniprot id: A0A2U4BZK1
uniprot id: A0A2U4BZP7
uniprot id: A0A2U4BZP8
uniprot id: A0A2U4BZS1
names: Similarity
messages: Belongs to the FAM161 family.

9739:A2M
gene id: 9739:A2M
uniprot id: A0A2U4AKU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

9739:BCL2L1
gene id: 9739:BCL2L1
uniprot id: A0A2U3V0P1
uniprot id: A0A2U4CLR5
uniprot id: A0A2U4CLY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane
messages: Mitochondrion matrix
messages: Nucleus membrane
messages: centrosome
messages: cytosol
messages: synaptic vesicle membrane

9739:NOTCH3
gene id: 9739:NOTCH3
uniprot id: A0A6J3R4E0
uniprot id: A0A6J3R4L0
uniprot id: A0A6J3R4L3
uniprot id: A0A6J3R529
uniprot id: A0A6J3R5C4
uniprot id: A0A6J3R6W4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

9739:CHURC1
gene id: 9739:CHURC1
uniprot id: A0A2U3V1L1
uniprot id: A0A2U4ABB9
names: Similarity
messages: Belongs to the Churchill family.

9739:TMEM45A
gene id: 9739:TMEM45A
uniprot id: A0A6J3RAI9
uniprot id: A0A6J3RBB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

9739:GRHL1
gene id: 9739:GRHL1
uniprot id: A0A2U4C064
uniprot id: A0A2U4C0A7
uniprot id: A0A6J3PUY8
names: Subcellular Location Annotation
messages: Nucleus

9739:ATP6V0D1
gene id: 9739:ATP6V0D1
uniprot id: A0A6J3QCZ9
uniprot id: A0A6J3QDE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

9739:MMUT
gene id: 9739:MMUT
uniprot id: A0A2U4CIV4
uniprot id: A0A2U4CIW7
names: Function
names: Similarity
messages: Belongs to the methylmalonyl-CoA mutase family.
messages: Catalyzes the reversible isomerization of methylmalonyl-CoA (MMCoA) (generated from branched-chain amino acid metabolism and degradation of dietary odd chain fatty acids and cholesterol) to succinyl-CoA (3-carboxypropionyl-CoA), a key intermediate of the tricarboxylic acid cycle.

9739:SLC9A9
gene id: 9739:SLC9A9
uniprot id: A0A2U4B9H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Endosome membrane
messages: Recycling endosome membrane

9739:SRXN1
gene id: 9739:SRXN1
uniprot id: A0A2U3V3L7
names: Similarity
messages: Belongs to the sulfiredoxin family.

9739:ATXN1
gene id: 9739:ATXN1
uniprot id: A0A2U4C4V7
uniprot id: A0A6J3RZ19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

9739:EXOSC9
gene id: 9739:EXOSC9
uniprot id: A0A2U4AR53
names: Subcellular Location Annotation
messages: Cytoplasm

9739:MAP1LC3A
gene id: 9739:MAP1LC3A
uniprot id: A0A2U4CLI0
names: Similarity
messages: Belongs to the ATG8 family.

9739:LOC101339275
gene id: 9739:LOC101339275
uniprot id: A0A6J3Q199
names: Subcellular Location Annotation
messages: Membrane

9739:TEKT4
gene id: 9739:TEKT4
uniprot id: A0A6J3Q1G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

9739:SPG21
gene id: 9739:SPG21
uniprot id: A0A2U4CEK0
uniprot id: A0A2U4CEL3
names: Function
messages: May play a role as a negative regulatory factor in CD4-dependent T-cell activation.

9739:TOPAZ1
gene id: 9739:TOPAZ1
uniprot id: A0A2U4C9U8
names: Function
messages: Important for normal spermatogenesis and male fertility. Specifically required for progression to the post-meiotic stages of spermatocyte development. Seems to be necessary for normal expression levels of a number of testis-expressed gene transcripts, although its role in this process is unclear.

9739:XYLT2
gene id: 9739:XYLT2
uniprot id: A0A6J3QMF4
uniprot id: A0A6J3QMK9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 14 family. XylT subfamily.
messages: Golgi apparatus membrane
messages: Membrane
messages: Monomer.

9739:SYBU
gene id: 9739:SYBU
uniprot id: A0A2U4BX97
uniprot id: A0A2U4BXA0
uniprot id: A0A2U4BXA2
uniprot id: A0A2U4BXA6
uniprot id: A0A2U4BXF2
uniprot id: A0A2U4BXF6
uniprot id: A0A2U4BXG0
names: Subcellular Location Annotation
messages: Membrane

9739:SOGA3
gene id: 9739:SOGA3
uniprot id: A0A6J3S932
uniprot id: A0A6J3SAL1
uniprot id: A0A6J3SAL4
uniprot id: A0A6J3SAN1
names: Similarity
messages: Belongs to the SOGA family.

9739:CCNO
gene id: 9739:CCNO
uniprot id: A0A2U3V9J9
names: Similarity
messages: Belongs to the cyclin family.

9739:SNTA1
gene id: 9739:SNTA1
uniprot id: A0A6J3Q1L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

9739:KCNN2
gene id: 9739:KCNN2
uniprot id: A0A2U4BTC5
uniprot id: A0A6J3R4S0
names: Subcellular Location Annotation
messages: Membrane

9739:GALR2
gene id: 9739:GALR2
uniprot id: A0A2U3UYI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

9739:AP3B2
gene id: 9739:AP3B2
uniprot id: A0A6J3R0A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes large subunit family.
messages: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
messages: clathrin-coated vesicle membrane

9739:LOC101339274
gene id: 9739:LOC101339274
uniprot id: A0A6J3QT35
names: Subcellular Location Annotation
messages: Membrane

9739:MIEF2
gene id: 9739:MIEF2
uniprot id: A0A2U4AD71
uniprot id: A0A2U4ADF9
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

9739:CASP6
gene id: 9739:CASP6
uniprot id: A0A2U4AQX0
uniprot id: A0A2U4AQX2
uniprot id: A0A2U4ARB5
uniprot id: A0A6J3RD12
names: Similarity
messages: Belongs to the peptidase C14A family.

9739:LIFR
gene id: 9739:LIFR
uniprot id: A0A2U4AXI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

9739:AKT2
gene id: 9739:AKT2
uniprot id: A0A6J3QII2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

9739:BHMT
gene id: 9739:BHMT
uniprot id: A0A2U3V0H1
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

9739:ADAMTS14
gene id: 9739:ADAMTS14
uniprot id: A0A6J3Q5V0
uniprot id: A0A6J3Q5V3
uniprot id: A0A6J3Q5V6
uniprot id: A0A6J3Q656
uniprot id: A0A6J3Q6H9
uniprot id: A0A6J3Q6L1
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9739:TPMT
gene id: 9739:TPMT
uniprot id: A0A2U4C5M9
uniprot id: A0A2U4C5N7
uniprot id: A0A2U4C5V8
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Monomer.

9739:SMC6
gene id: 9739:SMC6
uniprot id: A0A2U4C012
names: Subcellular Location Annotation
messages: Chromosome

9739:LOC117312405
gene id: 9739:LOC117312405
uniprot id: A0A6J3PUT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EAF6 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
messages: Component of the NuA4 histone acetyltransferase complex. Component of the hbo1 complex. Component of the moz/morf complex.
messages: kinetochore
messages: nucleolus

9739:ATP8B3
gene id: 9739:ATP8B3
uniprot id: A0A6J3R8B0
names: Subcellular Location Annotation
messages: Membrane

9739:PFKFB4
gene id: 9739:PFKFB4
uniprot id: A0A6J3S1K2
uniprot id: A0A6J3S1N0
uniprot id: A0A6J3S1Q0
uniprot id: A0A6J3S295
uniprot id: A0A6J3S2A1
uniprot id: A0A6J3S2N9
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

9739:POLG
gene id: 9739:POLG
uniprot id: A0A6J3R0K9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: Heterotrimer composed of a catalytic subunit and a homodimer of accessory subunits.
messages: Involved in the replication of mitochondrial DNA. Associates with mitochondrial DNA.
messages: mitochondrion nucleoid

9739:CAB39L
gene id: 9739:CAB39L
uniprot id: A0A2U4BG25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

9739:ATP13A4
gene id: 9739:ATP13A4
uniprot id: A0A2U4AD14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

9739:NAXE
gene id: 9739:NAXE
uniprot id: A0A2U3UZD2
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NnrE/AIBP family.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. Accelerates cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis.
messages: Homodimer. Interacts with APOA1 and APOA2.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Secreted
messages: Undergoes physiological phosphorylation during sperm capacitation, downstream to PKA activation.

9739:MIXL1
gene id: 9739:MIXL1
uniprot id: A0A2U3V5A5
uniprot id: A0A6J3QMP1
names: Subcellular Location Annotation
messages: Nucleus

9739:SEC31B
gene id: 9739:SEC31B
uniprot id: A0A6J3Q833
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC31 family.
messages: Endoplasmic reticulum membrane

9739:LOC101316807
gene id: 9739:LOC101316807
uniprot id: A0A2U4CDA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9739:BNIP3
gene id: 9739:BNIP3
uniprot id: A0A2U4BRQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

9739:SF3A3
gene id: 9739:SF3A3
uniprot id: A0A2U4BKF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3A3 family.
messages: Nucleus

9739:DMAP1
gene id: 9739:DMAP1
uniprot id: A0A2U4BJT4
uniprot id: A0A2U4BK83
names: Subcellular Location Annotation
messages: Nucleus

9739:OVOL1
gene id: 9739:OVOL1
uniprot id: A0A6J3RQK5
uniprot id: A0A6J3RRJ1
uniprot id: A0A6J3RRJ9
names: Subcellular Location Annotation
messages: Nucleus

9739:RAMP3
gene id: 9739:RAMP3
uniprot id: A0A6J3RVY5
names: Similarity
messages: Belongs to the RAMP family.

9739:CMTM4
gene id: 9739:CMTM4
uniprot id: A0A2U4BDV7
names: Subcellular Location Annotation
messages: Membrane

9739:LIPE
gene id: 9739:LIPE
uniprot id: A0A6J3QHM1
uniprot id: A0A6J3QHQ3
uniprot id: A0A6J3QHQ8
uniprot id: A0A6J3QIQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 'GDXG' lipolytic enzyme family.
messages: Cell membrane
messages: Lipid droplet
messages: caveola
messages: cytosol

9739:FMO3
gene id: 9739:FMO3
uniprot id: A0A2U4CQE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

9739:SULT1E1
gene id: 9739:SULT1E1
uniprot id: A0A2U3V2U3
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9739:FAM171B
gene id: 9739:FAM171B
uniprot id: A0A2U4B1L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

9739:CACNA1E
gene id: 9739:CACNA1E
uniprot id: A0A6J3R4M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents.

9739:RBM46
gene id: 9739:RBM46
uniprot id: A0A6J3REE6
uniprot id: A0A6J3RF72
names: Subcellular Location Annotation
messages: Cytoplasm

9739:RNF167
gene id: 9739:RNF167
uniprot id: A0A6J3QKC6
names: Subcellular Location Annotation
messages: Membrane

9739:C4BPB
gene id: 9739:C4BPB
uniprot id: A0A2U4CQR8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:PIK3C2A
gene id: 9739:PIK3C2A
uniprot id: A0A2U4CEL6
uniprot id: A0A2U4CEL8
uniprot id: A0A2U4CEL9
uniprot id: A0A2U4CEM0
uniprot id: A0A6J3RV99
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

9739:ZBTB8OS
gene id: 9739:ZBTB8OS
uniprot id: A0A2U3V6Z0
uniprot id: A0A2U4BKM9
uniprot id: A0A2U4BKN4
uniprot id: A0A2U4BKR8
uniprot id: A0A6J3PWY6
names: Similarity
names: Subunit
messages: Belongs to the archease family.
messages: Component of the tRNA-splicing ligase complex.

9739:HIBCH
gene id: 9739:HIBCH
uniprot id: A0A2U4B1I1
uniprot id: A0A2U4B1I5
uniprot id: A0A6J3RMB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA.
messages: Mitochondrion

9739:TMEM144
gene id: 9739:TMEM144
uniprot id: A0A2U3V725
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM144 family.
messages: Membrane

9739:CRK
gene id: 9739:CRK
uniprot id: A0A2U4ANU3
names: Similarity
messages: Belongs to the CRK family.

9739:LOC101325417
gene id: 9739:LOC101325417
uniprot id: A0A6J3SAR5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

9739:SNX4
gene id: 9739:SNX4
uniprot id: A0A2U4ABW3
names: Similarity
messages: Belongs to the sorting nexin family.

9739:SYNE2
gene id: 9739:SYNE2
uniprot id: A0A2U4ABP8
uniprot id: A0A2U4ABQ7
uniprot id: A0A2U4ABS1
uniprot id: A0A2U4ABS3
uniprot id: A0A2U4ABU4
uniprot id: A0A2U4ABV3
uniprot id: A0A2U4ABV4
uniprot id: A0A2U4ABX1
names: Similarity
messages: Belongs to the nesprin family.

9739:SEC22C
gene id: 9739:SEC22C
uniprot id: A0A2U3V2U5
uniprot id: A0A2U4CAC8
uniprot id: A0A6J3S110
uniprot id: A0A6J3S1M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in vesicle transport between the ER and the Golgi complex.
messages: Membrane

9739:AGXT
gene id: 9739:AGXT
uniprot id: A0A6J3RNL3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: Peroxisome

9739:FAM110C
gene id: 9739:FAM110C
uniprot id: A0A2U4C0F8
names: Similarity
messages: Belongs to the FAM110 family.

9739:GRIA1
gene id: 9739:GRIA1
uniprot id: A0A2U4AH75
uniprot id: A0A2U4AH88
uniprot id: A0A2U4AHE6
uniprot id: A0A6J3R4K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

9739:HGD
gene id: 9739:HGD
uniprot id: A0A2U4AC17
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

9739:SMAD3
gene id: 9739:SMAD3
uniprot id: A0A6J3QZ19
uniprot id: A0A6J3QZC7
uniprot id: A0A6J3QZT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

9739:MAST2
gene id: 9739:MAST2
uniprot id: A0A2U4BJN1
uniprot id: A0A2U4BJQ1
uniprot id: A0A2U4BJU6
uniprot id: A0A6J3S856
uniprot id: A0A6J3S8E2
uniprot id: A0A6J3S8P6
uniprot id: A0A6J3S9W3
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

9739:SPTLC2
gene id: 9739:SPTLC2
uniprot id: A0A2U4A400
uniprot id: A0A2U4A402
uniprot id: A0A6J3QVZ8
uniprot id: A0A6J3QWW3
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

9739:TMBIM6
gene id: 9739:TMBIM6
uniprot id: A0A2U4B9Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

9739:MYBBP1A
gene id: 9739:MYBBP1A
uniprot id: A0A6J3QML1
names: Similarity
messages: Belongs to the MYBBP1A family.

9739:TOMM40
gene id: 9739:TOMM40
uniprot id: A0A6J3QCX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

9739:TAFA1
gene id: 9739:TAFA1
uniprot id: A0A2U4CCY0
names: Similarity
messages: Belongs to the TAFA family.

9739:MSH3
gene id: 9739:MSH3
uniprot id: A0A2U4AWY8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).

9739:PPP1R1B
gene id: 9739:PPP1R1B
uniprot id: A0A6J3QMR8
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 1 family.

9739:USP39
gene id: 9739:USP39
uniprot id: A0A2U4BX22
uniprot id: A0A2U4BX27
uniprot id: A0A2U4BX75
uniprot id: A0A2U4BX81
names: Subcellular Location Annotation
messages: Nucleus

9739:CRY2
gene id: 9739:CRY2
uniprot id: A0A2U3UZB4
uniprot id: A0A6J3RP83
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 FAD per subunit.

9739:THNSL2
gene id: 9739:THNSL2
uniprot id: A0A2U4BXB7
uniprot id: A0A2U4BXC1
uniprot id: A0A2U4BXC6
uniprot id: A0A6J3PW52
names: Similarity
messages: Belongs to the threonine synthase family.

9739:RASGRP3
gene id: 9739:RASGRP3
uniprot id: A0A2U4C044
names: Similarity
messages: Belongs to the RASGRP family.

9739:CDH1
gene id: 9739:CDH1
uniprot id: A0A2U4BD90
uniprot id: A0A2U4BDA7
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

9739:LOC117312963
gene id: 9739:LOC117312963
uniprot id: A0A6J3RMP2
names: Subcellular Location Annotation
messages: Cytoplasm

9739:CENPT
gene id: 9739:CENPT
uniprot id: A0A2U3V4U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-T/CNN1 family.
messages: Nucleus
messages: kinetochore

9739:LOC101320480
gene id: 9739:LOC101320480
uniprot id: A0A2U4A0L9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9739:MARVELD2
gene id: 9739:MARVELD2
uniprot id: A0A2U3V241
uniprot id: A0A2U4AWY3
uniprot id: A0A2U4AWZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

9739:ASIC3
gene id: 9739:ASIC3
uniprot id: A0A6J3RXR6
uniprot id: A0A6J3RXX3
names: Subcellular Location Annotation
messages: Membrane

9739:LOC101322737
gene id: 9739:LOC101322737
uniprot id: A0A6J3QMG5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:PHACTR3
gene id: 9739:PHACTR3
uniprot id: A0A6J3PZS7
uniprot id: A0A6J3Q064
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

9739:MYOC
gene id: 9739:MYOC
uniprot id: A0A2U4CQE1
uniprot id: A0A6J3RB77
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:MRPS31
gene id: 9739:MRPS31
uniprot id: A0A2U4BGA2
uniprot id: A0A2U4BGA4
uniprot id: A0A2U4BGD5
uniprot id: A0A2U4BGP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS31 family.
messages: Mitochondrion

9739:MATN2
gene id: 9739:MATN2
uniprot id: A0A6J3Q9Q8
uniprot id: A0A6J3QA32
uniprot id: A0A6J3QAG6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:DHFR
gene id: 9739:DHFR
uniprot id: A0A2U3UZS0
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

9739:ELAC2
gene id: 9739:ELAC2
uniprot id: A0A2U4C2R3
uniprot id: A0A2U4C2S4
uniprot id: A0A2U4C2T1
uniprot id: A0A2U4C2V5
uniprot id: A0A2U4C2Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Z family.
messages: mitochondrion nucleoid

9739:EXOSC3
gene id: 9739:EXOSC3
uniprot id: A0A2U3V2J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP40 family.
messages: Cytoplasm
messages: nucleolus

9739:PANX2
gene id: 9739:PANX2
uniprot id: A0A6J3S471
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

9739:NDUFB10
gene id: 9739:NDUFB10
uniprot id: A0A2U3V1S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit that is involved in the functional assembly of the mitochondrial respiratory chain complex I. Complex I has an NADH dehydrogenase activity with ubiquinone as an immediate electron acceptor and mediates the transfer of electrons from NADH to the respiratory chain.
messages: Belongs to the complex I NDUFB10 subunit family.
messages: Mitochondrion inner membrane

9739:LMOD1
gene id: 9739:LMOD1
uniprot id: A0A6J3QDL4
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

9739:UTP6
gene id: 9739:UTP6
uniprot id: A0A2U3V1W2
uniprot id: A0A2U4APA1
uniprot id: A0A6J3QKH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP6 family.
messages: nucleolus

9739:GJE1
gene id: 9739:GJE1
uniprot id: A0A6J3S9Z8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9739:TRMT44
gene id: 9739:TRMT44
uniprot id: A0A2U4CNB4
uniprot id: A0A6J3RDC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.
messages: Belongs to the TRM44 family.
messages: Cytoplasm

9739:DNM1
gene id: 9739:DNM1
uniprot id: A0A6J3RIM7
uniprot id: A0A6J3RIN2
uniprot id: A0A6J3RIX5
uniprot id: A0A6J3RIY8
uniprot id: A0A6J3RJP5
uniprot id: A0A6J3RJQ0
uniprot id: A0A6J3RKM7
uniprot id: A0A6J3RKN1
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

9739:SPSB2
gene id: 9739:SPSB2
uniprot id: A0A2U4AL76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

9739:RIBC1
gene id: 9739:RIBC1
uniprot id: A0A2U4C129
names: Similarity
messages: Belongs to the RIB43A family.

9739:LOC101326359
gene id: 9739:LOC101326359
uniprot id: A0A2U4ARN8
uniprot id: A0A2U4ARN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

9739:ACSS3
gene id: 9739:ACSS3
uniprot id: A0A2U4CQM0
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

9739:S100A8
gene id: 9739:S100A8
uniprot id: A0A2U3VA32
names: Similarity
messages: Belongs to the S-100 family.

9739:OSMR
gene id: 9739:OSMR
uniprot id: A0A6J3R2J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

9739:TRIO
gene id: 9739:TRIO
uniprot id: A0A2U4CMC8
uniprot id: A0A2U4CMD3
uniprot id: A0A2U4CMJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cytoplasm

9739:TAF1
gene id: 9739:TAF1
uniprot id: A0A6J3QT62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF1 family.
messages: Nucleus

9739:FAM189A1
gene id: 9739:FAM189A1
uniprot id: A0A6J3R101
names: Similarity
messages: Belongs to the ENTREP family.

9739:LOC101336026
gene id: 9739:LOC101336026
uniprot id: A0A2U4BTI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

9739:LOC101324898
gene id: 9739:LOC101324898
uniprot id: A0A6J3RKA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9739:NEUROD6
gene id: 9739:NEUROD6
uniprot id: A0A2U3V5G9
names: Subcellular Location Annotation
messages: Nucleus

9739:KDSR
gene id: 9739:KDSR
uniprot id: A0A2U4BI40
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9739:LOC101323075
gene id: 9739:LOC101323075
uniprot id: A0A6J3RVN7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the splicing factor SR family.
messages: Found in mRNA splicing-dependent exon junction complexes (EJC). Found in a post-splicing complex with NXF1, RBM8A, UPF1, UPF2, UPF3A, UPF3B and RNPS1. Component of the heterotrimeric ASAP (apoptosis- and splicing-associated protein) and PSAP complexes consisting of RNPS1, SAP18 and either ACIN1 or PNN, respectively; the ASAP and PSAP complexes probably are formed mutually exclusive. Component of the active spliceosome. Associates with polysomes. Interacts with the cleaved p110 isoform of CDC2L1, CSNK2A1, PNN, SART3, SRP54, SRRM1 and TRA2B/SFRS10.
messages: Nucleus speckle

9739:HSF1
gene id: 9739:HSF1
uniprot id: A0A6J3Q971
uniprot id: A0A6J3Q973
uniprot id: A0A6J3Q9L7
uniprot id: A0A6J3Q9M2
uniprot id: A0A6J3Q9Y3
uniprot id: A0A6J3QA09
uniprot id: A0A6J3QA14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

9739:EDEM3
gene id: 9739:EDEM3
uniprot id: A0A2U4CS95
uniprot id: A0A6J3R4C8
uniprot id: A0A6J3R632
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

9739:CYHR1
gene id: 9739:CYHR1
uniprot id: A0A6J3Q8R7
uniprot id: A0A6J3Q8S0
names: Similarity
messages: Belongs to the ZFTRAF1 family.

9739:SS18L1
gene id: 9739:SS18L1
uniprot id: A0A6J3Q3M3
names: Similarity
messages: Belongs to the SS18 family.

9739:LOC117309469
gene id: 9739:LOC117309469
uniprot id: A0A6J3QLV9
names: Similarity
messages: Belongs to the intermediate filament family.

9739:STOML3
gene id: 9739:STOML3
uniprot id: A0A2U4BGQ8
names: Similarity
messages: Belongs to the band 7/mec-2 family.

9739:LHCGR
gene id: 9739:LHCGR
uniprot id: A0A2U4BY13
uniprot id: A0A6J3PW38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

9739:MGAT5
gene id: 9739:MGAT5
uniprot id: A0A2U4AJC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 18 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Secreted

9739:DNPEP
gene id: 9739:DNPEP
uniprot id: A0A6J3RML6
uniprot id: A0A6J3RN11
names: Similarity
names: Subunit
messages: Belongs to the peptidase M18 family.
messages: Tetrahedron-shaped homododecamer built from six homodimers.

9739:LOC101316131
gene id: 9739:LOC101316131
uniprot id: A0A2U3V7K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

9739:TLR7
gene id: 9739:TLR7
uniprot id: A0A2U3V3D5
uniprot id: A0A6J3QUQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Endoplasmic reticulum membrane
messages: Endosome
messages: Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production.
messages: Lysosome
messages: Membrane
messages: phagosome

9739:ADRB2
gene id: 9739:ADRB2
uniprot id: A0A2U3V401
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB2 sub-subfamily.
messages: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.
messages: Cell membrane
messages: Early endosome
messages: Golgi apparatus
messages: Membrane

9739:GSDMC
gene id: 9739:GSDMC
uniprot id: A0A6J3Q8Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

9739:NEK3
gene id: 9739:NEK3
uniprot id: A0A2U4BGC0
uniprot id: A0A2U4BGM9
names: Similarity
messages: Belongs to the protein kinase superfamily.

9739:FGD6
gene id: 9739:FGD6
uniprot id: A0A2U3ZZL0
uniprot id: A0A2U4A0J0
names: Subcellular Location Annotation
messages: cytoskeleton

9739:GSTK1
gene id: 9739:GSTK1
uniprot id: A0A2U3V3Y8
uniprot id: A0A2U4B8M6
names: Similarity
messages: Belongs to the GST superfamily. Kappa family.

9739:ATP2B1
gene id: 9739:ATP2B1
uniprot id: A0A2U4CRZ5
uniprot id: A0A2U4CS13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:PHKA2
gene id: 9739:PHKA2
uniprot id: A0A6J3QTD5
uniprot id: A0A6J3QTE1
uniprot id: A0A6J3QTX6
uniprot id: A0A6J3QTY1
uniprot id: A0A6J3QTY3
uniprot id: A0A6J3QU57
uniprot id: A0A6J3QU61
uniprot id: A0A6J3QUC3
uniprot id: A0A6J3QUC8
uniprot id: A0A6J3QUD2
uniprot id: A0A6J3QV35
uniprot id: A0A6J3QV40
uniprot id: A0A6J3QV44
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

9739:SRP54
gene id: 9739:SRP54
uniprot id: A0A2U4AF52
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9. Interacts with RNPS1. Interacts with the SRP receptor subunit SRPRA.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). As part of the SRP complex, associates with the SRP receptor (SR) component SRPRA to target secretory proteins to the endoplasmic reticulum membrane. Binds to the signal sequence of presecretory proteins when they emerge from the ribosomes. Displays basal GTPase activity, and stimulates reciprocal GTPase activation of the SR subunit SRPRA. Forms a guanosine 5'-triphosphate (GTP)-dependent complex with the SR subunit SRPRA. SR compaction and GTPase mediated rearrangement of SR drive SRP-mediated cotranslational protein translocation into the ER. Requires the presence of SRP9/SRP14 and/or SRP19 to stably interact with RNA. Plays a role in proliferation and differentiation of granulocytic cells, neutrophils migration capacity and exocrine pancreas development.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Nucleus speckle
messages: The M domain binds the 7SL RNA in presence of SRP19 and binds the signal sequence of presecretory proteins.
messages: The NG domain, also named G domain, is a special guanosine triphosphatase (GTPase) domain, which binds GTP and forms a guanosine 5'-triphosphate (GTP)-dependent complex with a homologous NG domain in the SRP receptor subunit SRPRA. The two NG domains undergo cooperative rearrangements upon their assembly, which culminate in the reciprocal activation of the GTPase activity of one another. SRP receptor compaction upon binding with cargo-loaded SRP and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER.

9739:PNRC2
gene id: 9739:PNRC2
uniprot id: A0A2U4BLV6
names: Subcellular Location Annotation
messages: Nucleus

9739:LOC117312218
gene id: 9739:LOC117312218
uniprot id: A0A2U4BEB1
names: Similarity
messages: Belongs to the protein kinase superfamily.

9739:SLC9A8
gene id: 9739:SLC9A8
uniprot id: A0A6J3Q2H7
uniprot id: A0A6J3Q2N2
uniprot id: A0A6J3Q2S5
uniprot id: A0A6J3Q372
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

9739:KCNJ14
gene id: 9739:KCNJ14
uniprot id: A0A6J3QI91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

9739:ATR
gene id: 9739:ATR
uniprot id: A0A2U4B9F6
uniprot id: A0A2U4B9G3
uniprot id: A0A2U4B9J6
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.

9739:LOC101325461
gene id: 9739:LOC101325461
uniprot id: A0A6J3RJR4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space
messages: Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

9739:GPAT3
gene id: 9739:GPAT3
uniprot id: A0A2U4B5I2
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

9739:WNT9A
gene id: 9739:WNT9A
uniprot id: A0A6J3R4V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9739:LASP1
gene id: 9739:LASP1
uniprot id: A0A6J3QMW0
names: Function
names: Subcellular Location Annotation
messages: Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types.
messages: cell cortex
messages: cytoskeleton

9739:LOC101331987
gene id: 9739:LOC101331987
uniprot id: A0A6J3RSF7
names: Similarity
messages: Belongs to the calcitonin family.

9739:LOC101318567
gene id: 9739:LOC101318567
uniprot id: A0A2U4CA22
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

9739:SEC22B
gene id: 9739:SEC22B
uniprot id: A0A2U4A3K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Melanosome
messages: Membrane
messages: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

9739:LOC101331460
gene id: 9739:LOC101331460
uniprot id: A0A2U4C4V0
uniprot id: A0A2U4C4W3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9739:SNCG
gene id: 9739:SNCG
uniprot id: A0A6J3Q7Z2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synuclein family.
messages: May be a centrosome-associated protein. Interacts with MYOC; affects its secretion and its aggregation.
messages: spindle

9739:TNXB
gene id: 9739:TNXB
uniprot id: A0A6J3RZB5
uniprot id: A0A6J3RZF2
uniprot id: A0A6J3RZL9
uniprot id: A0A6J3S0A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family.
messages: extracellular matrix

9739:ZNF330
gene id: 9739:ZNF330
uniprot id: A0A2U4AM88
uniprot id: A0A2U4AML8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOA36 family.
messages: centromere
messages: nucleolus

9739:PNKD
gene id: 9739:PNKD
uniprot id: A0A6J3RM71
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

9739:TMEM176A
gene id: 9739:TMEM176A
uniprot id: A0A6J3RVL8
names: Similarity
messages: Belongs to the TMEM176 family.

9739:LOC101322435
gene id: 9739:LOC101322435
uniprot id: A0A2U4CMW4
uniprot id: A0A2U4CN30
names: Similarity
messages: Belongs to the cytochrome P450 family.

9739:LMX1B
gene id: 9739:LMX1B
uniprot id: A0A6J3RJB9
uniprot id: A0A6J3RKC4
names: Subcellular Location Annotation
messages: Nucleus

9739:MMP15
gene id: 9739:MMP15
uniprot id: A0A6J3QE54
uniprot id: A0A6J3QEN3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

9739:DPH3
gene id: 9739:DPH3
uniprot id: A0A2U3V7M7
uniprot id: A0A6J3RBG1
names: Similarity
messages: Belongs to the DPH3 family.

9739:SDHAF4
gene id: 9739:SDHAF4
uniprot id: A0A2U3V8A7
names: Similarity
messages: Belongs to the SDHAF4 family.

9739:LRRC8C
gene id: 9739:LRRC8C
uniprot id: A0A2U4A3W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

9739:RAB4B
gene id: 9739:RAB4B
uniprot id: A0A6J3QCW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport.

9739:LOC117312609
gene id: 9739:LOC117312609
uniprot id: A0A6J3RGL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

9739:LOC101331229
gene id: 9739:LOC101331229
uniprot id: A0A6J3RYP3
uniprot id: A0A6J3RYU0
uniprot id: A0A6J3RYZ3
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

9739:MCL1
gene id: 9739:MCL1
uniprot id: A0A2U3V2H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Cytoplasm
messages: Membrane
messages: nucleoplasm

9739:CTDP1
gene id: 9739:CTDP1
uniprot id: A0A6J3PUC7
uniprot id: A0A6J3PUD2
uniprot id: A0A6J3PUI0
uniprot id: A0A6J3PUV6
uniprot id: A0A6J3PUW0
uniprot id: A0A6J3PV90
uniprot id: A0A6J3PV97
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: This promotes the activity of RNA polymerase II.

9739:NLRP3
gene id: 9739:NLRP3
uniprot id: A0A6J3R4Z3
names: Similarity
messages: Belongs to the NLRP family.

9739:ACTBL2
gene id: 9739:ACTBL2
uniprot id: A0A6J3R2G4
names: Similarity
messages: Belongs to the actin family.

9739:ASXL2
gene id: 9739:ASXL2
uniprot id: A0A2U3UZV5
uniprot id: A0A2U4BZN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Asx family.
messages: Nucleus

9739:PRMT5
gene id: 9739:PRMT5
uniprot id: A0A2U3V060
uniprot id: A0A2U3V0A8
uniprot id: A0A2U4CFA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA).
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Nucleus

9739:STING1
gene id: 9739:STING1
uniprot id: A0A2U4AGG1
uniprot id: A0A2U4AGI2
uniprot id: A0A2U4AGN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STING family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Mitochondrion outer membrane
messages: autophagosome membrane
messages: perinuclear region

9739:RNF152
gene id: 9739:RNF152
uniprot id: A0A2U4BHM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNF152 family.
messages: Lysosome membrane
messages: Membrane

9739:LOC101333685
gene id: 9739:LOC101333685
uniprot id: A0A6J3QQR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family.
messages: Cytoplasm

9739:EFEMP1
gene id: 9739:EFEMP1
uniprot id: A0A2U4BY41
uniprot id: A0A2U4BY46
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:LOC101328944
gene id: 9739:LOC101328944
uniprot id: A0A2U3V257
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9739:BEST1
gene id: 9739:BEST1
uniprot id: A0A6J3RQ59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.
messages: Cell membrane
messages: Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
messages: Membrane

9739:WRNIP1
gene id: 9739:WRNIP1
uniprot id: A0A2U4C528
uniprot id: A0A2U4C531
uniprot id: A0A2U4C584
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

9739:ZNF622
gene id: 9739:ZNF622
uniprot id: A0A2U4CMK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the REI1 family.
messages: Cytoplasm

9739:ZIC5
gene id: 9739:ZIC5
uniprot id: A0A2U4A637
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

9739:CCNT2
gene id: 9739:CCNT2
uniprot id: A0A2U4AJ54
uniprot id: A0A2U4AJ55
uniprot id: A0A2U4AJ57
uniprot id: A0A2U4AJ59
uniprot id: A0A2U4AJD2
uniprot id: A0A2U4AJQ6
names: Similarity
messages: Belongs to the cyclin family.

9739:HLX
gene id: 9739:HLX
uniprot id: A0A2U4A588
names: Subcellular Location Annotation
messages: Nucleus

9739:WNT6
gene id: 9739:WNT6
uniprot id: A0A6J3RLB7
uniprot id: A0A6J3RN40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9739:TFAP2A
gene id: 9739:TFAP2A
uniprot id: A0A2U4C5A7
uniprot id: A0A2U4C5B1
uniprot id: A0A2U4C5B3
uniprot id: A0A2U4C5C8
uniprot id: A0A2U4C5D3
uniprot id: A0A2U4C5J2
uniprot id: A0A2U4C5K2
uniprot id: A0A6J3RYM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AP-2 family.
messages: Nucleus

9739:KCNB2
gene id: 9739:KCNB2
uniprot id: A0A2U4AIE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.2/KCNB2 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: Perikaryon
messages: dendrite

9739:RIMKLA
gene id: 9739:RIMKLA
uniprot id: A0A2U4BK08
names: Similarity
messages: Belongs to the RimK family.

9739:CCNA1
gene id: 9739:CCNA1
uniprot id: A0A2U3V5Z2
uniprot id: A0A2U4BGK6
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

9739:SLC22A4
gene id: 9739:SLC22A4
uniprot id: A0A6J3R4Y4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Basal cell membrane
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
messages: Interacts with PDZK1.

9739:NGDN
gene id: 9739:NGDN
uniprot id: A0A2U3V4E6
uniprot id: A0A6J3QXT4
uniprot id: A0A6J3QXX5
uniprot id: A0A6J3QYF1
uniprot id: A0A6J3QZB0
names: Subcellular Location Annotation
messages: nucleolus

9739:FEN1
gene id: 9739:FEN1
uniprot id: A0A2U3UZS9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Mitochondrion
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
messages: nucleolus
messages: nucleoplasm

9739:ZFYVE27
gene id: 9739:ZFYVE27
uniprot id: A0A6J3Q640
uniprot id: A0A6J3Q644
uniprot id: A0A6J3Q645
uniprot id: A0A6J3Q6H2
uniprot id: A0A6J3Q6V5
uniprot id: A0A6J3Q6W6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: growth cone membrane

9739:LOC117308158
gene id: 9739:LOC117308158
uniprot id: A0A6J3Q137
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

9739:PLPPR1
gene id: 9739:PLPPR1
uniprot id: A0A2U4CG70
uniprot id: A0A6J3RKJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

9739:KCNJ9
gene id: 9739:KCNJ9
uniprot id: A0A6J3RD74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

9739:ERH
gene id: 9739:ERH
uniprot id: A0A2U3V022
names: Function
names: Similarity
messages: Belongs to the E(R) family.
messages: May have a role in the cell cycle.

9739:CPE
gene id: 9739:CPE
uniprot id: A0A2U4AN74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M14 family.
messages: Interacts with Secretogranin III/SCG3.
messages: Membrane
messages: Sorting receptor that directs prohormones to the regulated secretory pathway. Acts also as a prohormone processing enzyme in neuro/endocrine cells, removing dibasic residues from the C-terminal end of peptide hormone precursors after initial endoprotease cleavage.
messages: secretory vesicle membrane

9739:GALNT6
gene id: 9739:GALNT6
uniprot id: A0A6J3S858
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9739:NOG
gene id: 9739:NOG
uniprot id: A0A2U4C648
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the noggin family.
messages: Homodimer.
messages: Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.
messages: Secreted

9739:IRF2BP2
gene id: 9739:IRF2BP2
uniprot id: A0A6J3Q596
uniprot id: A0A6J3Q5T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF2BP family.
messages: Nucleus

9739:NFKB1
gene id: 9739:NFKB1
uniprot id: A0A2U4AM53
uniprot id: A0A2U4AM57
uniprot id: A0A2U4AM64
uniprot id: A0A2U4AM69
uniprot id: A0A2U4AM87
uniprot id: A0A2U4AMJ4
uniprot id: A0A2U4AMJ9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9739:CCNY
gene id: 9739:CCNY
uniprot id: A0A2U4B6U1
names: Similarity
messages: Belongs to the cyclin family. Cyclin Y subfamily.

9739:BHMT2
gene id: 9739:BHMT2
uniprot id: A0A2U3V0Z7
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

9739:BRIX1
gene id: 9739:BRIX1
uniprot id: A0A2U3V6G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRX1 family.
messages: Required for biogenesis of the 60S ribosomal subunit.
messages: nucleolus

9739:FGF20
gene id: 9739:FGF20
uniprot id: A0A2U3V6M5
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9739:LOC101336135
gene id: 9739:LOC101336135
uniprot id: A0A2U4B2S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane
messages: pH-dependent, voltage-insensitive, background potassium channel protein.

9739:HDHD2
gene id: 9739:HDHD2
uniprot id: A0A2U4BH78
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

9739:RPS11
gene id: 9739:RPS11
uniprot id: A0A6J3QDF7
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

9739:TCF7L1
gene id: 9739:TCF7L1
uniprot id: A0A6J3PVG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

9739:IL2RG
gene id: 9739:IL2RG
uniprot id: A0A6J3QSY3
names: Subcellular Location Annotation
messages: Membrane

9739:LOC117312921
gene id: 9739:LOC117312921
uniprot id: A0A6J3RL55
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

9739:LCN10
gene id: 9739:LCN10
uniprot id: A0A6J3RKC7
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

9739:LOC101324157
gene id: 9739:LOC101324157
uniprot id: A0A2U3V8F2
names: Similarity
messages: Belongs to the PRR23 family.

9739:GEMIN2
gene id: 9739:GEMIN2
uniprot id: A0A2U4AF07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gemin-2 family.
messages: Cytoplasm

9739:PTPN21
gene id: 9739:PTPN21
uniprot id: A0A2U4A287
uniprot id: A0A6J3QWE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

9739:POU3F4
gene id: 9739:POU3F4
uniprot id: A0A6J3QTI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

9739:LOC101334320
gene id: 9739:LOC101334320
uniprot id: A0A2U4A3S9
names: Similarity
messages: Belongs to the cornifin (SPRR) family.

9739:FAXC
gene id: 9739:FAXC
uniprot id: A0A6J3S925
uniprot id: A0A6J3SAD4
uniprot id: A0A6J3SAF2
names: Similarity
messages: Belongs to the FAX family.

9739:MPI
gene id: 9739:MPI
uniprot id: A0A2U3UZH4
uniprot id: A0A2U3UZI3
uniprot id: A0A2U4CIN7
uniprot id: A0A2U4CIP6
uniprot id: A0A2U4CIQ6
uniprot id: A0A2U4CIV3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

9739:HDAC4
gene id: 9739:HDAC4
uniprot id: A0A6J3RKM4
uniprot id: A0A6J3RLU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

9739:LOC117312935
gene id: 9739:LOC117312935
uniprot id: A0A2U4AAR0
uniprot id: A0A6J3RNF0
names: Subcellular Location Annotation
messages: Nucleus

9739:RUNDC3A
gene id: 9739:RUNDC3A
uniprot id: A0A6J3QJS4
uniprot id: A0A6J3QJS9
uniprot id: A0A6J3QJX5
uniprot id: A0A6J3QKF7
uniprot id: A0A6J3QKG0
uniprot id: A0A6J3QKH7
uniprot id: A0A6J3QKI3
uniprot id: A0A6J3QKX4
names: Similarity
messages: Belongs to the RUNDC3 family.

9739:LOC101324400
gene id: 9739:LOC101324400
uniprot id: A0A2U3VAR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

9739:WASL
gene id: 9739:WASL
uniprot id: A0A2U4AGU2
names: Subcellular Location Annotation
messages: Nucleus

9739:DESI1
gene id: 9739:DESI1
uniprot id: A0A2U4C2H3
names: Similarity
messages: Belongs to the DeSI family.

9739:RRP8
gene id: 9739:RRP8
uniprot id: A0A2U3V872
uniprot id: A0A2U4CDH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RRP8 family.
messages: Component of the eNoSC complex.
messages: Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase.
messages: nucleolus

9739:MTIF3
gene id: 9739:MTIF3
uniprot id: A0A2U4BGP1
uniprot id: A0A2U4BGP3
names: Similarity
messages: Belongs to the IF-3 family.

9739:LOC101333380
gene id: 9739:LOC101333380
uniprot id: A0A2U4C4U1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9739:EIF2B1
gene id: 9739:EIF2B1
uniprot id: A0A2U4CK18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.
messages: Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
messages: Complex of five different subunits; alpha, beta, gamma, delta and epsilon.

9739:PTPN6
gene id: 9739:PTPN6
uniprot id: A0A6J3S7F4
uniprot id: A0A6J3S7R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm

9739:PIWIL1
gene id: 9739:PIWIL1
uniprot id: A0A2U3V9L6
names: Similarity
messages: Belongs to the argonaute family.

9739:EIPR1
gene id: 9739:EIPR1
uniprot id: A0A2U4C0A9
uniprot id: A0A6J3PV15
uniprot id: A0A6J3PVD2
uniprot id: A0A6J3PVD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat EIPR1 family.
messages: trans-Golgi network

9739:SLC66A2
gene id: 9739:SLC66A2
uniprot id: A0A2U4BHY1
uniprot id: A0A2U4BI28
uniprot id: A0A6J3PUI8
uniprot id: A0A6J3PUU3
names: Subcellular Location Annotation
messages: Membrane

9739:RABAC1
gene id: 9739:RABAC1
uniprot id: A0A6J3QE21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

9739:ATP5ME
gene id: 9739:ATP5ME
uniprot id: A0A6J3RC46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase e subunit family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

9739:USP5
gene id: 9739:USP5
uniprot id: A0A6J3S7S0
uniprot id: A0A6J3S7S5
uniprot id: A0A6J3S820
uniprot id: A0A6J3S915
uniprot id: A0A6J3S920
uniprot id: A0A6J3S990
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

9739:PLIN2
gene id: 9739:PLIN2
uniprot id: A0A2U4BB51
uniprot id: A0A2U4BB83
uniprot id: A0A6J3RH59
names: Similarity
messages: Belongs to the perilipin family.

9739:ALG9
gene id: 9739:ALG9
uniprot id: A0A2U4BW81
uniprot id: A0A2U4BW84
uniprot id: A0A2U4BWD9
uniprot id: A0A2U4BWE2
uniprot id: A0A2U4BWE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:ZNF75D
gene id: 9739:ZNF75D
uniprot id: A0A2U4A0R1
uniprot id: A0A2U4A1P1
names: Subcellular Location Annotation
messages: Nucleus

9739:SLC7A5
gene id: 9739:SLC7A5
uniprot id: A0A6J3QJ51
uniprot id: A0A6J3QJM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Cell membrane
messages: Membrane

9739:NFRKB
gene id: 9739:NFRKB
uniprot id: A0A6J3RSR6
uniprot id: A0A6J3RTB6
names: Subcellular Location Annotation
messages: Nucleus

9739:SLC13A3
gene id: 9739:SLC13A3
uniprot id: A0A2U4C1Y8
uniprot id: A0A2U4C274
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

9739:LOC117312608
gene id: 9739:LOC117312608
uniprot id: A0A6J3RHG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

9739:ABCB7
gene id: 9739:ABCB7
uniprot id: A0A2U4B3C2
uniprot id: A0A2U4B3C6
uniprot id: A0A2U4B3D8
uniprot id: A0A2U4B3H2
uniprot id: A0A2U4B3R6
names: Subcellular Location Annotation
messages: Membrane

9739:NEUROD1
gene id: 9739:NEUROD1
uniprot id: A0A2U4B1H9
names: Subcellular Location Annotation
messages: Nucleus

9739:THBS1
gene id: 9739:THBS1
uniprot id: A0A6J3QZP8
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:LOC101332615
gene id: 9739:LOC101332615
uniprot id: A0A2U4BFL7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: nucleoplasm
messages: podosome

9739:GGA1
gene id: 9739:GGA1
uniprot id: A0A6J3S4V5
uniprot id: A0A6J3S563
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

9739:MRPS18C
gene id: 9739:MRPS18C
uniprot id: A0A2U3V8U7
uniprot id: A0A2U4B5D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Mitochondrion

9739:NCAPD2
gene id: 9739:NCAPD2
uniprot id: A0A2U4AKP1
uniprot id: A0A2U4AKP8
uniprot id: A0A2U4AL52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND1 (condensin subunit 1) family.
messages: Chromosome
messages: Nucleus
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

9739:NR4A1
gene id: 9739:NR4A1
uniprot id: A0A6J3S6W0
uniprot id: A0A6J3S7Q5
uniprot id: A0A6J3S7R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR4 subfamily.
messages: In the cytosol, upon its detection of both bacterial lipopolysaccharide (LPS) and NBRE-containing mitochondrial DNA released by GSDMD pores during pyroptosis, it promotes non-canonical NLRP3 inflammasome activation by stimulating association of NLRP3 and NEK7.
messages: Nucleus
messages: cytosol

9739:ALG6
gene id: 9739:ALG6
uniprot id: A0A2U4A2J9
uniprot id: A0A2U4A2K3
uniprot id: A0A2U4A2K7
uniprot id: A0A2U4A2M2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:OLFM4
gene id: 9739:OLFM4
uniprot id: A0A2U4BFI6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:TSC22D2
gene id: 9739:TSC22D2
uniprot id: A0A2U4B9L7
uniprot id: A0A2U4B9P3
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

9739:TXNL4A
gene id: 9739:TXNL4A
uniprot id: A0A6J3PUD7
uniprot id: A0A6J3PUJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

9739:NDUFV1
gene id: 9739:NDUFV1
uniprot id: A0A6J3RRL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 51 kDa subunit family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion inner membrane

9739:CALHM6
gene id: 9739:CALHM6
uniprot id: A0A2U3V6T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

9739:TOMM20L
gene id: 9739:TOMM20L
uniprot id: A0A2U3VB31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

9739:KCNMB1
gene id: 9739:KCNMB1
uniprot id: A0A6J3R4F8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KCNMB (TC 8.A.14.1) family.
messages: Interacts with KCNMA1 tetramer. There are probably 4 molecules of KCMNB per KCNMA1 tetramer.
messages: Membrane
messages: N-glycosylated.
messages: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity.

9739:NT5DC3
gene id: 9739:NT5DC3
uniprot id: A0A2U4CR23
uniprot id: A0A6J3S530
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

9739:LOC109550911
gene id: 9739:LOC109550911
uniprot id: A0A2U4BV22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

9739:RAB39B
gene id: 9739:RAB39B
uniprot id: A0A2U3V474
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

9739:AKIRIN2
gene id: 9739:AKIRIN2
uniprot id: A0A2U3V6P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

9739:NUP107
gene id: 9739:NUP107
uniprot id: A0A2U3ZZE8
uniprot id: A0A2U3ZZF0
uniprot id: A0A2U3ZZG6
uniprot id: A0A2U3ZZG7
uniprot id: A0A6J3S5N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup84/Nup107 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: Part of the nuclear pore complex (NPC).
messages: nuclear pore complex

9739:IMPG1
gene id: 9739:IMPG1
uniprot id: A0A2U4AUU7
uniprot id: A0A2U4AVA8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: interphotoreceptor matrix

9739:NUBP2
gene id: 9739:NUBP2
uniprot id: A0A6J3Q0X2
uniprot id: A0A6J3Q169
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
messages: Cytoplasm
messages: Heterotetramer of 2 NUBP1 and 2 NUBP2 chains. Interacts with KIFC1.
messages: Nucleus
messages: centrosome

9739:ELF4
gene id: 9739:ELF4
uniprot id: A0A6J3QTW6
uniprot id: A0A6J3QUE0
uniprot id: A0A6J3QUK3
uniprot id: A0A6J3QUU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9739:JUNB
gene id: 9739:JUNB
uniprot id: A0A6J3R831
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

9739:MDH2
gene id: 9739:MDH2
uniprot id: A0A6J3Q0N3
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

9739:LOC101318445
gene id: 9739:LOC101318445
uniprot id: A0A2U3V7N2
uniprot id: A0A2U4BQ54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX15/CtaA family.
messages: Membrane

9739:LOC117313936
gene id: 9739:LOC117313936
uniprot id: A0A6J3S2Z1
names: Similarity
messages: Belongs to the actin family.

9739:GPI
gene id: 9739:GPI
uniprot id: A0A2U4BTJ9
names: Similarity
messages: Belongs to the GPI family.

9739:GPR18
gene id: 9739:GPR18
uniprot id: A0A2U3V689
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9739:PABPC1L
gene id: 9739:PABPC1L
uniprot id: A0A6J3Q2W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

9739:POP5
gene id: 9739:POP5
uniprot id: A0A2U3V1K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
messages: nucleolus

9739:ALDH1A3
gene id: 9739:ALDH1A3
uniprot id: A0A2U4C7S4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

9739:AFF1
gene id: 9739:AFF1
uniprot id: A0A2U4AMR0
uniprot id: A0A2U4AMR3
uniprot id: A0A2U4AMR7
uniprot id: A0A2U4AMR8
uniprot id: A0A2U4AMS3
uniprot id: A0A2U4AMU3
uniprot id: A0A2U4AMU7
uniprot id: A0A2U4AN55
uniprot id: A0A2U4AN60
uniprot id: A0A6J3REC2
uniprot id: A0A6J3RF47
names: Similarity
messages: Belongs to the AF4 family.

9739:KEG93 p03
gene id: 9739:KEG93_p03
uniprot id: B9UD86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

9739:FAM219A
gene id: 9739:FAM219A
uniprot id: A0A6J3RGD0
uniprot id: A0A6J3RGK7
uniprot id: A0A6J3RGV7
uniprot id: A0A6J3RGW0
uniprot id: A0A6J3RH78
uniprot id: A0A6J3RH84
uniprot id: A0A6J3RIK6
names: Similarity
messages: Belongs to the FAM219 family.

9739:DSCC1
gene id: 9739:DSCC1
uniprot id: A0A2U4B382
names: Similarity
messages: Belongs to the DCC1 family.

9739:PIEZO1
gene id: 9739:PIEZO1
uniprot id: A0A6J3QIS3
uniprot id: A0A6J3QJC4
uniprot id: A0A6J3QJF0
uniprot id: A0A6J3QJV6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIEZO (TC 1.A.75) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:POU6F2
gene id: 9739:POU6F2
uniprot id: A0A2U4BSM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

9739:DERL1
gene id: 9739:DERL1
uniprot id: A0A2U4B314
uniprot id: A0A2U4B329
uniprot id: A0A2U4B3G4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:CTNNA3
gene id: 9739:CTNNA3
uniprot id: A0A6J3Q6F3
names: Similarity
messages: Belongs to the vinculin/alpha-catenin family.

9739:LOC101326611
gene id: 9739:LOC101326611
uniprot id: A0A2U3V308
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9739:ENO3
gene id: 9739:ENO3
uniprot id: A0A6J3QKH2
uniprot id: A0A6J3QLH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

9739:LOC101339769
gene id: 9739:LOC101339769
uniprot id: A0A6J3Q338
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB11 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane

9739:EMP1
gene id: 9739:EMP1
uniprot id: A0A2U4BID0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:IGF2BP3
gene id: 9739:IGF2BP3
uniprot id: A0A6J3RWD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM IMP/VICKZ family.
messages: P-body
messages: Stress granule

9739:PROX1
gene id: 9739:PROX1
uniprot id: A0A6J3R3H2
names: Subcellular Location Annotation
messages: Nucleus

9739:RC3H1
gene id: 9739:RC3H1
uniprot id: A0A2U4CQB2
uniprot id: A0A2U4CQB3
uniprot id: A0A2U4CQL9
uniprot id: A0A6J3R7Y6
names: Subcellular Location Annotation
messages: P-body

9739:CIAO1
gene id: 9739:CIAO1
uniprot id: A0A2U4B0C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat CIA1 family.
messages: Component of the CIA complex. Component of the MMXD complex, which includes CIAO1, ERCC2, FAM96B, MMS19 and SLC25A5. Interacts with WT1. Interacts with FAM96A.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation.

9739:TACC3
gene id: 9739:TACC3
uniprot id: A0A6J3RC48
uniprot id: A0A6J3RD16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

9739:AQP11
gene id: 9739:AQP11
uniprot id: A0A2U3V2J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.
messages: Cell membrane
messages: Membrane

9739:SLC4A7
gene id: 9739:SLC4A7
uniprot id: A0A2U4CAI1
uniprot id: A0A2U4CAI3
uniprot id: A0A2U4CAJ0
uniprot id: A0A2U4CAQ5
uniprot id: A0A6J3S1L2
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane

9739:PSMB8
gene id: 9739:PSMB8
uniprot id: A0A2U4B1D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

9739:CCR2
gene id: 9739:CCR2
uniprot id: A0A2U3UZ29
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9739:LOC117313170
gene id: 9739:LOC117313170
uniprot id: A0A6J3RQQ1
names: Similarity
messages: Belongs to the peptidase A1 family.

9739:CAV3
gene id: 9739:CAV3
uniprot id: A0A2U3V3K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

9739:NEK9
gene id: 9739:NEK9
uniprot id: A0A2U4A683
uniprot id: A0A2U4A6A2
uniprot id: A0A2U4A6Y5
names: Similarity
messages: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.

9739:SERINC3
gene id: 9739:SERINC3
uniprot id: A0A6J3PY19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

9739:ZNF483
gene id: 9739:ZNF483
uniprot id: A0A2U4C9G1
names: Subcellular Location Annotation
messages: Nucleus

9739:B4GALT1
gene id: 9739:B4GALT1
uniprot id: A0A2U4BBB8
uniprot id: A0A6J3RGI5
uniprot id: A0A6J3RGR4
uniprot id: A0A6J3RGZ8
uniprot id: A0A6J3RHC9
uniprot id: A0A6J3RIQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

9739:ST6GALNAC3
gene id: 9739:ST6GALNAC3
uniprot id: A0A6J3S117
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9739:NFX1
gene id: 9739:NFX1
uniprot id: A0A2U4BBC3
uniprot id: A0A6J3RGQ8
uniprot id: A0A6J3RGZ4
uniprot id: A0A6J3RHC2
uniprot id: A0A6J3RIP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NFX1 family.
messages: Nucleus

9739:NIPSNAP2
gene id: 9739:NIPSNAP2
uniprot id: A0A6J3Q3U2
uniprot id: A0A6J3Q4C0
names: Similarity
messages: Belongs to the NipSnap family.

9739:PPP1R35
gene id: 9739:PPP1R35
uniprot id: A0A2U4AYY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP1R35 family.
messages: centriole

9739:CSMD3
gene id: 9739:CSMD3
uniprot id: A0A2U4B2P9
uniprot id: A0A2U4B2S5
uniprot id: A0A6J3Q997
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:NOBOX
gene id: 9739:NOBOX
uniprot id: A0A6J3RVP2
names: Subcellular Location Annotation
messages: Nucleus

9739:TGFA
gene id: 9739:TGFA
uniprot id: A0A6J3PVX7
uniprot id: A0A6J3PW61
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:ATP6V1C2
gene id: 9739:ATP6V1C2
uniprot id: A0A6J3PUW9
uniprot id: A0A6J3PV79
uniprot id: A0A6J3PV89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits.

9739:MAS1
gene id: 9739:MAS1
uniprot id: A0A2U4CNZ6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9739:TNFSF14
gene id: 9739:TNFSF14
uniprot id: A0A0U5JAG2
uniprot id: A0A6J3R6P7
names: Similarity
messages: Belongs to the tumor necrosis factor family.

9739:LOC117310192
gene id: 9739:LOC117310192
uniprot id: A0A6J3QRR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Golgi apparatus
messages: May play an important role in formation and fusion of Golgi-derived vesicles during acrosome biogenesis.
messages: Nucleus
messages: cytoskeleton

9739:POLR1C
gene id: 9739:POLR1C
uniprot id: A0A2U4CIU9
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

9739:SFMBT2
gene id: 9739:SFMBT2
uniprot id: A0A6J3R2H7
names: Subcellular Location Annotation
messages: Nucleus

9739:AP2A2
gene id: 9739:AP2A2
uniprot id: A0A6J3RS90
uniprot id: A0A6J3RSH3
uniprot id: A0A6J3RSL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit AP2A1 or AP2A2 and beta-type subunit AP2B1), a medium adaptin (mu-type subunit AP2M1) and a small adaptin (sigma-type subunit AP2S1).
messages: Belongs to the adaptor complexes large subunit family.
messages: Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules. AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway. The AP-2 alpha subunit binds polyphosphoinositide-containing lipids, positioning AP-2 on the membrane. The AP-2 alpha subunit acts via its C-terminal appendage domain as a scaffolding platform for endocytic accessory proteins. The AP-2 alpha and AP-2 sigma subunits are thought to contribute to the recognition of the [ED]-X-X-X-L-[LI] motif.
messages: coated pit

9739:PHC2
gene id: 9739:PHC2
uniprot id: A0A2U4BKI0
uniprot id: A0A2U4BKI2
names: Subcellular Location Annotation
messages: Nucleus

9739:LOC117313277
gene id: 9739:LOC117313277
uniprot id: A0A6J3RT03
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9739:BCL2L13
gene id: 9739:BCL2L13
uniprot id: A0A6J3S7Z8
names: Similarity
messages: Belongs to the Bcl-2 family.

9739:YTHDF2
gene id: 9739:YTHDF2
uniprot id: A0A2U3V112
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

9739:HNMT
gene id: 9739:HNMT
uniprot id: A0A2U3V2X6
uniprot id: A0A2U4AJA4
names: Function
names: Subunit
messages: Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine.
messages: Monomer.

9739:MYOZ3
gene id: 9739:MYOZ3
uniprot id: A0A6J3R870
uniprot id: A0A6J3R9B7
names: Similarity
messages: Belongs to the myozenin family.

9739:SBDS
gene id: 9739:SBDS
uniprot id: A0A2U4A9F0
names: Function
names: Similarity
messages: Belongs to the SDO1/SBDS family.
messages: Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.

9739:RARG
gene id: 9739:RARG
uniprot id: A0A6J3S675
uniprot id: A0A6J3S6Q6
uniprot id: A0A6J3S7K9
uniprot id: A0A6J3S7X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

9739:TBCD
gene id: 9739:TBCD
uniprot id: A0A6J3QKY1
names: Similarity
messages: Belongs to the TBCD family.

9739:MAP3K7
gene id: 9739:MAP3K7
uniprot id: A0A2U4AVL4
uniprot id: A0A2U4AVN0
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by pro-inflammatory cytokines and in response to physical and chemical stresses, including osmotic stress, oxidative stress, arsenic and ultraviolet light irradiation. Activated by 'Lys-63'-linked polyubiquitination and by autophosphorylation.
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Cytoplasm

9739:CDCA7
gene id: 9739:CDCA7
uniprot id: A0A2U3V4J0
uniprot id: A0A2U3V4Y6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9739:SEMA3G
gene id: 9739:SEMA3G
uniprot id: A0A6J3S2C2
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:PSME1
gene id: 9739:PSME1
uniprot id: A0A2U3V134
names: Similarity
messages: Belongs to the PA28 family.

9739:MAN2A2
gene id: 9739:MAN2A2
uniprot id: A0A6J3QZW9
uniprot id: A0A6J3QZX2
uniprot id: A0A6J3R068
uniprot id: A0A6J3R073
uniprot id: A0A6J3R078
uniprot id: A0A6J3R0K7
uniprot id: A0A6J3R0L7
uniprot id: A0A6J3R0P9
uniprot id: A0A6J3R1Y4
uniprot id: A0A6J3R1Z0
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

9739:EVA1C
gene id: 9739:EVA1C
uniprot id: A0A2U4ACP4
uniprot id: A0A2U4ACR7
uniprot id: A0A2U4AD86
uniprot id: A0A6J3RBN1
names: Similarity
messages: Belongs to the EVA1 family.

9739:ASL
gene id: 9739:ASL
uniprot id: A0A6J3PY31
names: Similarity
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

9739:NBR1
gene id: 9739:NBR1
uniprot id: A0A2U3UZJ0
uniprot id: A0A2U4BPD4
uniprot id: A0A2U4BPJ1
names: Subcellular Location Annotation
messages: Lysosome
messages: autophagosome

9739:CUL2
gene id: 9739:CUL2
uniprot id: A0A2U3V5Q5
names: Similarity
messages: Belongs to the cullin family.

9739:DNER
gene id: 9739:DNER
uniprot id: A0A2U4AE04
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:LOC101318336
gene id: 9739:LOC101318336
uniprot id: A0A2U3V7R9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

9739:PNN
gene id: 9739:PNN
uniprot id: A0A2U4AEZ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pinin family.
messages: Found in a mRNA splicing-dependent exon junction complex (EJC). Found in a complex with SR proteins. Found in a mRNP complex with RNPS1. Component of the PSAP complex consisting of RNPS1, SAP18 and PNN. Interacts with PNISR, CTBP1, CTBP2, KRT8, KRT18, KRT19, PS1D/PNO40, PPIG, RNPS1, SFRS4 and SRRM2. Identified in the spliceosome C complex.
messages: Nucleus speckle
messages: desmosome

9739:SCUBE3
gene id: 9739:SCUBE3
uniprot id: A0A6J3RY83
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9739:CNOT1
gene id: 9739:CNOT1
uniprot id: A0A2U4BDJ2
uniprot id: A0A2U4BDJ6
uniprot id: A0A2U4BDK4
uniprot id: A0A2U4BDK9
uniprot id: A0A2U4BDN7
uniprot id: A0A2U4BDP2
uniprot id: A0A2U4BDW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT1 family.
messages: Nucleus

9739:MYO18A
gene id: 9739:MYO18A
uniprot id: A0A6J3QPQ7
uniprot id: A0A6J3QPR2
uniprot id: A0A6J3QPU6
uniprot id: A0A6J3QPV1
uniprot id: A0A6J3QPV6
uniprot id: A0A6J3QPW1
uniprot id: A0A6J3QQE9
uniprot id: A0A6J3QQF4
uniprot id: A0A6J3QQF9
uniprot id: A0A6J3QQK3
uniprot id: A0A6J3QQK7
uniprot id: A0A6J3QQX3
uniprot id: A0A6J3QQX8
uniprot id: A0A6J3QQY3
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:SGSM2
gene id: 9739:SGSM2
uniprot id: A0A6J3QNE8
uniprot id: A0A6J3QNK4
uniprot id: A0A6J3QNK8
uniprot id: A0A6J3QP03
uniprot id: A0A6J3QPA6
uniprot id: A0A6J3QPM9
names: Similarity
messages: Belongs to the RUTBC family.

9739:MAU2
gene id: 9739:MAU2
uniprot id: A0A6J3R585
uniprot id: A0A6J3R680
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC4/mau-2 family.
messages: nucleoplasm

9739:BMP6
gene id: 9739:BMP6
uniprot id: A0A6J3RYM5
uniprot id: A0A6J3RYS1
names: Similarity
messages: Belongs to the TGF-beta family.

9739:VPS13D
gene id: 9739:VPS13D
uniprot id: A0A2U4AZL0
uniprot id: A0A2U4AZL4
uniprot id: A0A2U4AZL5
uniprot id: A0A2U4AZL7
uniprot id: A0A2U4AZM2
uniprot id: A0A2U4AZP2
uniprot id: A0A2U4AZP6
uniprot id: A0A2U4B010
uniprot id: A0A6J3Q9E5
uniprot id: A0A6J3Q9Q6
uniprot id: A0A6J3QA48
names: Similarity
messages: Belongs to the VPS13 family.

9739:PURB
gene id: 9739:PURB
uniprot id: A0A2U4BN77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

9739:AZIN2
gene id: 9739:AZIN2
uniprot id: A0A2U4BKJ0
uniprot id: A0A2U4BKJ2
uniprot id: A0A2U4BKW6
uniprot id: A0A2U4BKX1
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

9739:EXT2
gene id: 9739:EXT2
uniprot id: A0A2U4CDS4
uniprot id: A0A6J3RNP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:GRK1
gene id: 9739:GRK1
uniprot id: A0A6J3QC19
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

9739:NGFR
gene id: 9739:NGFR
uniprot id: A0A6J3QP51
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:CD47
gene id: 9739:CD47
uniprot id: A0A2U4AAT2
uniprot id: A0A2U4ABE1
uniprot id: A0A6J3RCX8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9739:IQSEC1
gene id: 9739:IQSEC1
uniprot id: A0A6J3S3A8
uniprot id: A0A6J3S3G1
uniprot id: A0A6J3S3J1
uniprot id: A0A6J3S482
names: Similarity
messages: Belongs to the BRAG family.

9739:PSMB3
gene id: 9739:PSMB3
uniprot id: A0A2U4AI06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

9739:PGM1
gene id: 9739:PGM1
uniprot id: A0A6J3S3A4
uniprot id: A0A6J3S3B3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

9739:CFAP97
gene id: 9739:CFAP97
uniprot id: A0A2U4A7I1
names: Similarity
messages: Belongs to the CFAP97 family.

9739:FGFR1
gene id: 9739:FGFR1
uniprot id: A0A6J3QQI1
uniprot id: A0A6J3QQL6
uniprot id: A0A6J3QQM2
uniprot id: A0A6J3QR79
uniprot id: A0A6J3QR86
uniprot id: A0A6J3QRA0
uniprot id: A0A6J3QRA4
uniprot id: A0A6J3QRQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Membrane
messages: Nucleus
messages: Vesicle
messages: cytosol

9739:SV2A
gene id: 9739:SV2A
uniprot id: A0A2U4A297
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

9739:GJB4
gene id: 9739:GJB4
uniprot id: A0A6J3PW31
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9739:KCNJ3
gene id: 9739:KCNJ3
uniprot id: A0A2U4A9Z1
uniprot id: A0A2U4AAB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
messages: Membrane
messages: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

9739:DDX27
gene id: 9739:DDX27
uniprot id: A0A2U4C1L8
names: Similarity
messages: Belongs to the DEAD box helicase family.

9739:PCNX3
gene id: 9739:PCNX3
uniprot id: A0A6J3RQG8
uniprot id: A0A6J3RQH6
uniprot id: A0A6J3RQS7
uniprot id: A0A6J3RQT2
uniprot id: A0A6J3RQX7
uniprot id: A0A6J3RQY3
uniprot id: A0A6J3RRF5
uniprot id: A0A6J3RRG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

9739:DNTTIP2
gene id: 9739:DNTTIP2
uniprot id: A0A2U4A2M9
uniprot id: A0A2U4A2Q9
uniprot id: A0A6J3RXG1
names: Subcellular Location Annotation
messages: nucleolus

9739:OTULINL
gene id: 9739:OTULINL
uniprot id: A0A6J3R2E4
uniprot id: A0A6J3R3R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C65 family. Otulin subfamily.
messages: Cytoplasm

9739:LOC101333468
gene id: 9739:LOC101333468
uniprot id: A0A6J3R6P2
uniprot id: A0A6J3R6P8
uniprot id: A0A6J3R6S1
uniprot id: A0A6J3R6S6
uniprot id: A0A6J3R6T1
uniprot id: A0A6J3R770
uniprot id: A0A6J3R776
uniprot id: A0A6J3R7M3
uniprot id: A0A6J3R7M8
uniprot id: A0A6J3R9F9
names: Subcellular Location Annotation
messages: Nucleus

9739:ABCA2
gene id: 9739:ABCA2
uniprot id: A0A6J3RJR7
uniprot id: A0A6J3RK14
uniprot id: A0A6J3RK38
uniprot id: A0A6J3RKX0
names: Subcellular Location Annotation
messages: Membrane

9739:LOC101326072
gene id: 9739:LOC101326072
uniprot id: A0A2U4AW65
uniprot id: A0A2U4AWK6
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9739:RANBP6
gene id: 9739:RANBP6
uniprot id: A0A2U3V717
uniprot id: A0A2U3V718
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9739:SMPD1
gene id: 9739:SMPD1
uniprot id: A0A2U3V7Z9
uniprot id: A0A2U4CEN3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Converts sphingomyelin to ceramide.
messages: Secreted

9739:ROGDI
gene id: 9739:ROGDI
uniprot id: A0A6J3Q195
uniprot id: A0A6J3Q196
uniprot id: A0A6J3Q1J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rogdi family.
messages: Presynapse
messages: Vesicle
messages: synaptic vesicle

9739:CLDN14
gene id: 9739:CLDN14
uniprot id: A0A2U3V5U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9739:DLK1
gene id: 9739:DLK1
uniprot id: A0A6J3R1B0
uniprot id: A0A6J3R1J5
uniprot id: A0A6J3R1U2
uniprot id: A0A6J3R357
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:VSTM5
gene id: 9739:VSTM5
uniprot id: A0A6J3RU86
names: Subcellular Location Annotation
messages: Membrane

9739:ATG2B
gene id: 9739:ATG2B
uniprot id: A0A2U3ZYL0
uniprot id: A0A2U3ZZI3
uniprot id: A0A2U4CS47
uniprot id: A0A2U4CS70
uniprot id: A0A2U4CS85
uniprot id: A0A6J3QXJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG2 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Preautophagosomal structure membrane

9739:UNC50
gene id: 9739:UNC50
uniprot id: A0A2U3V1U7
uniprot id: A0A2U4B0H1
uniprot id: A0A2U4B0H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-50 family.
messages: Membrane
messages: Nucleus inner membrane

9739:VCAN
gene id: 9739:VCAN
uniprot id: A0A6J3R2B0
uniprot id: A0A6J3R2E8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aggrecan/versican proteoglycan family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9739:TMED5
gene id: 9739:TMED5
uniprot id: A0A2U4A2Q7
uniprot id: A0A2U4A2Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

9739:LOC109549802
gene id: 9739:LOC109549802
uniprot id: A0A6J3RGW6
names: Subcellular Location Annotation
messages: Nucleus

9739:PLCD1
gene id: 9739:PLCD1
uniprot id: A0A6J3S1D2
uniprot id: A0A6J3S1U5
names: Cofactor
messages: Binds 3 Ca(2+) ions per subunit. Two of the Ca(2+) ions are bound to the C2 domain.

9739:PRIMPOL
gene id: 9739:PRIMPOL
uniprot id: A0A2U4A7Q5
uniprot id: A0A2U4A7Q8
uniprot id: A0A2U4A7Q9
uniprot id: A0A6J3QQC6
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

9739:CRYL1
gene id: 9739:CRYL1
uniprot id: A0A2U4BH29
uniprot id: A0A2U4BHE3
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

9739:PRPF38A
gene id: 9739:PRPF38A
uniprot id: A0A2U4BJG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRP38 family.
messages: Component of the spliceosome B complex.
messages: Involved in pre-mRNA splicing as a component of the spliceosome.
messages: Nucleus

9739:SPPL2B
gene id: 9739:SPPL2B
uniprot id: A0A6J3R7H1
uniprot id: A0A6J3R7J7
uniprot id: A0A6J3R7Z9
uniprot id: A0A6J3R8J0
uniprot id: A0A6J3RAB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Endosome membrane
messages: Lysosome membrane
messages: Membrane

9739:CHRNE
gene id: 9739:CHRNE
uniprot id: A0A6J3QPA0
uniprot id: A0A6J3QQ51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9739:EPB41
gene id: 9739:EPB41
uniprot id: A0A2U4BKU8
uniprot id: A0A2U4BKV0
uniprot id: A0A2U4BKV2
uniprot id: A0A2U4BKV3
uniprot id: A0A2U4BKZ6
uniprot id: A0A2U4BL01
uniprot id: A0A2U4BL82
uniprot id: A0A6J3PYP1
uniprot id: A0A6J3PYP5
uniprot id: A0A6J3PYS0
uniprot id: A0A6J3PYX9
uniprot id: A0A6J3PYZ4
uniprot id: A0A6J3PZ11
uniprot id: A0A6J3PZ14
uniprot id: A0A6J3PZ25
uniprot id: A0A6J3PZ35
uniprot id: A0A6J3PZ44
uniprot id: A0A6J3PZ69
uniprot id: A0A6J3PZ97
uniprot id: A0A6J3PZA2
uniprot id: A0A6J3PZI4
names: Subcellular Location Annotation
messages: Nucleus
messages: cell cortex
messages: cytoskeleton

9739:ATP6AP1
gene id: 9739:ATP6AP1
uniprot id: A0A6J3QTG4
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

9739:PSMC2
gene id: 9739:PSMC2
uniprot id: A0A2U3V4V6
names: Similarity
messages: Belongs to the AAA ATPase family.

9739:AP4E1
gene id: 9739:AP4E1
uniprot id: A0A2U4AVN1
uniprot id: A0A2U4AVN9
uniprot id: A0A2U4AVP1
uniprot id: A0A2U4AVP9
uniprot id: A0A2U4AVQ7
uniprot id: A0A2U4AVR0
names: Function
names: Similarity
names: Subunit
messages: Adaptor protein complex 4 (AP-4) is a heterotetramer composed of two large adaptins, a medium adaptin and a small adaptin.
messages: Belongs to the adaptor complexes large subunit family.
messages: Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.

9739:LSM5
gene id: 9739:LSM5
uniprot id: A0A2U3V9B2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.

9739:ALKAL2
gene id: 9739:ALKAL2
uniprot id: A0A2U3V8U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALKAL family.
messages: Secreted

9739:COQ10A
gene id: 9739:COQ10A
uniprot id: A0A2U3ZZP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

9739:SNX21
gene id: 9739:SNX21
uniprot id: A0A2U4C1T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Membrane

9739:LOC101321752
gene id: 9739:LOC101321752
uniprot id: A0A2U3V257
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9739:LOC101329205
gene id: 9739:LOC101329205
uniprot id: A0A2U4BPB4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9739:RARA
gene id: 9739:RARA
uniprot id: A0A6J3QK40
uniprot id: A0A6J3QKM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

9739:RPL15
gene id: 9739:RPL15
uniprot id: A0A2U4CFG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL15 family.
messages: Cytoplasm

9739:MAST1
gene id: 9739:MAST1
uniprot id: A0A6J3R896
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

9739:PDS5B
gene id: 9739:PDS5B
uniprot id: A0A6J3QA70
uniprot id: A0A6J3QAD1
uniprot id: A0A6J3QAS5
uniprot id: A0A6J3QB03
uniprot id: A0A6J3QB46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDS5 family.
messages: Nucleus

9739:DDOST
gene id: 9739:DDOST
uniprot id: A0A2U3UYP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDOST 48 kDa subunit family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).

9739:PAX5
gene id: 9739:PAX5
uniprot id: A0A6J3RHB2
uniprot id: A0A6J3RHL2
names: Subcellular Location Annotation
messages: Nucleus

9739:FZD2
gene id: 9739:FZD2
uniprot id: A0A6J3QMX7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:CD93
gene id: 9739:CD93
uniprot id: A0A6J3Q1K9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:LTA4H
gene id: 9739:LTA4H
uniprot id: A0A2U3ZZD2
uniprot id: A0A2U3ZZD5
uniprot id: A0A2U3ZZF1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

9739:MTMR11
gene id: 9739:MTMR11
uniprot id: A0A6J3RMX6
uniprot id: A0A6J3RMY0
uniprot id: A0A6J3RNA4
uniprot id: A0A6J3RNQ0
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

9739:MYH7B
gene id: 9739:MYH7B
uniprot id: A0A6J3Q043
uniprot id: A0A6J3Q080
uniprot id: A0A6J3Q084
uniprot id: A0A6J3Q0D5
uniprot id: A0A6J3Q0E0
uniprot id: A0A6J3Q0R4
uniprot id: A0A6J3Q0R8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: myofibril

9739:SAXO2
gene id: 9739:SAXO2
uniprot id: A0A6J3R022
names: Similarity
messages: Belongs to the FAM154 family.

9739:ARL8B
gene id: 9739:ARL8B
uniprot id: A0A2U4CCM0
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: spindle

9739:GNS
gene id: 9739:GNS
uniprot id: A0A2U3V132
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Lysosome
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

9739:OGDHL
gene id: 9739:OGDHL
uniprot id: A0A6J3Q5R2
uniprot id: A0A6J3Q685
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

9739:TPPP
gene id: 9739:TPPP
uniprot id: A0A2U4CML3
uniprot id: A0A2U4CML9
names: Similarity
messages: Belongs to the TPPP family.

9739:PFKL
gene id: 9739:PFKL
uniprot id: A0A6J3RBF5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:AKR1B1
gene id: 9739:AKR1B1
uniprot id: A0A6J3RXG2
names: Similarity
messages: Belongs to the aldo/keto reductase family.

9739:LOC101320370
gene id: 9739:LOC101320370
uniprot id: A0A2U4AAF8
names: Subcellular Location Annotation
messages: Nucleus

9739:STAT4
gene id: 9739:STAT4
uniprot id: A0A2U4B1G2
uniprot id: A0A6J3RMA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

9739:MTMR9
gene id: 9739:MTMR9
uniprot id: A0A6J3RFF8
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

9739:MYO1D
gene id: 9739:MYO1D
uniprot id: A0A2U4ANX7
uniprot id: A0A2U4ANX8
uniprot id: A0A2U4ANY0
uniprot id: A0A2U4ANY3
uniprot id: A0A2U4ANY6
uniprot id: A0A2U4AP03
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

9739:SKIL
gene id: 9739:SKIL
uniprot id: A0A2U4C8R1
uniprot id: A0A2U4C8Y5
uniprot id: A0A6J3R987
names: Similarity
messages: Belongs to the SKI family.

9739:GBE1
gene id: 9739:GBE1
uniprot id: A0A2U4AB38
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

9739:LOC101317903
gene id: 9739:LOC101317903
uniprot id: A0A6J3REA4
names: Subcellular Location Annotation
messages: Membrane

9739:HTR1A
gene id: 9739:HTR1A
uniprot id: A0A2U3V7C9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.
messages: Membrane
messages: dendrite

9739:SETD6
gene id: 9739:SETD6
uniprot id: A0A2U4BDK0
uniprot id: A0A2U4BDX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily.
messages: Nucleus
messages: Protein-lysine N-methyltransferase.

9739:KBTBD8
gene id: 9739:KBTBD8
uniprot id: A0A2U3V4K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KBTBD8 family.
messages: Golgi apparatus
messages: spindle

9739:PPT2
gene id: 9739:PPT2
uniprot id: A0A6J3RZC8
uniprot id: A0A6J3RZE2
uniprot id: A0A6J3RZE7
uniprot id: A0A6J3RZJ3
uniprot id: A0A6J3RZR2
uniprot id: A0A6J3S0E9
names: Similarity
messages: Belongs to the palmitoyl-protein thioesterase family.

9739:DTX3L
gene id: 9739:DTX3L
uniprot id: A0A2U4ACN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

9739:DGKB
gene id: 9739:DGKB
uniprot id: A0A2U4B191
uniprot id: A0A2U4B1A3
uniprot id: A0A2U4B1M9
uniprot id: A0A2U4B1N3
uniprot id: A0A6J3RWH5
uniprot id: A0A6J3RX32
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

9739:TENT5A
gene id: 9739:TENT5A
uniprot id: A0A6J3S8S3
uniprot id: A0A6J3S944
names: Similarity
messages: Belongs to the TENT family.

9739:NUDT12
gene id: 9739:NUDT12
uniprot id: A0A2U4BTB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Cytoplasmic granule
messages: Peroxisome

9739:NFS1
gene id: 9739:NFS1
uniprot id: A0A2U3V877
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

9739:CLNS1A
gene id: 9739:CLNS1A
uniprot id: A0A2U3V2L8
uniprot id: A0A2U4CFY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pICln (TC 1.A.47) family.
messages: Nucleus

9739:LOC101328659
gene id: 9739:LOC101328659
uniprot id: A0A6J3QR76
uniprot id: A0A6J3QRJ2
uniprot id: A0A6J3QRZ7
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

9739:SYT17
gene id: 9739:SYT17
uniprot id: A0A2U4A8X3
uniprot id: A0A2U4A904
uniprot id: A0A2U4A9A2
uniprot id: A0A2U4A9M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Membrane

9739:LOC117312561
gene id: 9739:LOC117312561
uniprot id: A0A2U4CHA7
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9739:RPL22L1
gene id: 9739:RPL22L1
uniprot id: A0A2U3V7P0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

9739:USP38
gene id: 9739:USP38
uniprot id: A0A6J3RFH0
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

9739:SETD3
gene id: 9739:SETD3
uniprot id: A0A2U4CRL3
uniprot id: A0A2U4CRN0
uniprot id: A0A6J3QWI3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. SETD3 actin-histidine methyltransferase family.
messages: Cytoplasm
messages: Interacts with MYOD1.

9739:TSPYL1
gene id: 9739:TSPYL1
uniprot id: A0A2U4AW53
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9739:MARF1
gene id: 9739:MARF1
uniprot id: A0A6J3Q3Y5
uniprot id: A0A6J3Q3Z4
uniprot id: A0A6J3Q464
uniprot id: A0A6J3Q4D4
uniprot id: A0A6J3Q4E0
uniprot id: A0A6J3Q4P5
uniprot id: A0A6J3Q4Q1
names: Subcellular Location Annotation
messages: Peroxisome

9739:DEDD
gene id: 9739:DEDD
uniprot id: A0A2U3V5F9
names: Subcellular Location Annotation
messages: nucleolus

9739:F2RL3
gene id: 9739:F2RL3
uniprot id: A0A6J3R4U0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9739:ZDHHC5
gene id: 9739:ZDHHC5
uniprot id: A0A2U4CDC1
uniprot id: A0A2U4CDD0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9739:SMARCAD1
gene id: 9739:SMARCAD1
uniprot id: A0A2U3V3D6
uniprot id: A0A2U4AM03
names: Subcellular Location Annotation
messages: Chromosome

9739:POFUT1
gene id: 9739:POFUT1
uniprot id: A0A2U3V970
uniprot id: A0A2U4CLT3
names: Similarity
messages: Belongs to the glycosyltransferase 65 family.

9739:SNRPF
gene id: 9739:SNRPF
uniprot id: A0A2U4A0L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

9739:ANO10
gene id: 9739:ANO10
uniprot id: A0A2U4CAK0
uniprot id: A0A6J3S0V9
uniprot id: A0A6J3S0Y7
uniprot id: A0A6J3S1J4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:LOC101315909
gene id: 9739:LOC101315909
uniprot id: A0A2U3V4C9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9739:KAT5
gene id: 9739:KAT5
uniprot id: A0A6J3RQJ4
uniprot id: A0A6J3RQU8
uniprot id: A0A6J3RR07
uniprot id: A0A6J3RRI1
uniprot id: A0A6J3RRI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

9739:SLC16A5
gene id: 9739:SLC16A5
uniprot id: A0A6J3QPA8
uniprot id: A0A6J3QPS0
uniprot id: A0A6J3QPS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

9739:HSPB9
gene id: 9739:HSPB9
uniprot id: A0A6J3QPG5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

9739:SUPT3H
gene id: 9739:SUPT3H
uniprot id: A0A2U4CJ21
names: Subcellular Location Annotation
messages: Nucleus

9739:LOC117308943
gene id: 9739:LOC117308943
uniprot id: A0A6J3QCP5
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

9739:CEP57L1
gene id: 9739:CEP57L1
uniprot id: A0A2U4AVV4
uniprot id: A0A2U4AVW9
uniprot id: A0A6J3S957
names: Similarity
messages: Belongs to the translokin family.

9739:LOC101326663
gene id: 9739:LOC101326663
uniprot id: A0A2U4CDJ2
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

9739:CHRNA1
gene id: 9739:CHRNA1
uniprot id: A0A2U4AB01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9739:HK1
gene id: 9739:HK1
uniprot id: A0A6J3Q6N6
uniprot id: A0A6J3Q710
uniprot id: A0A6J3Q7E0
uniprot id: A0A6J3Q7F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hexokinase family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: cytosol

9739:AMOTL2
gene id: 9739:AMOTL2
uniprot id: A0A6J3R8T2
uniprot id: A0A6J3R8Z5
names: Similarity
messages: Belongs to the angiomotin family.

9739:GTF2H1
gene id: 9739:GTF2H1
uniprot id: A0A2U3V4W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB1 family.
messages: Nucleus

9739:INHBC
gene id: 9739:INHBC
uniprot id: A0A2U3V279
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

9739:TIMM17A
gene id: 9739:TIMM17A
uniprot id: A0A2U3UZA0
uniprot id: A0A2U4BI46
uniprot id: A0A6J3QDV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex at least composed of TIMM23, TIMM17 (TIMM17A or TIMM17B) and TIMM50.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

9739:FOXO4
gene id: 9739:FOXO4
uniprot id: A0A6J3QSG0
names: Subcellular Location Annotation
messages: Nucleus

9739:LOC101326214
gene id: 9739:LOC101326214
uniprot id: A0A2U3VA48
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

9739:NEU3
gene id: 9739:NEU3
uniprot id: A0A2U4C9L9
uniprot id: A0A2U4C9M0
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

9739:LOC101329993
gene id: 9739:LOC101329993
uniprot id: A0A2U4A0C9
uniprot id: A0A2U4A0D1
uniprot id: A0A2U4A0D7
uniprot id: A0A2U4A0E8
uniprot id: A0A2U4A0F4
uniprot id: A0A2U4A0F7
uniprot id: A0A2U4A0G1
uniprot id: A0A2U4A1D1
uniprot id: A0A2U4A1D6
uniprot id: A0A6J3Q9G8
names: Similarity
messages: Belongs to the DDI1 family.

9739:LOC101318043
gene id: 9739:LOC101318043
uniprot id: A0A6J3RES1
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

9739:RABGGTA
gene id: 9739:RABGGTA
uniprot id: A0A6J3QXA5
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.
messages: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX, such as RAB1A, RAB3A, RAB5A and RAB7A.

9739:MS4A3
gene id: 9739:MS4A3
uniprot id: A0A6J3RSN4
names: Similarity
messages: Belongs to the MS4A family.

9739:ZNF445
gene id: 9739:ZNF445
uniprot id: A0A2U4CA64
names: Subcellular Location Annotation
messages: Nucleus

9739:NOC2L
gene id: 9739:NOC2L
uniprot id: A0A6J3QIN6
uniprot id: A0A6J3QIP1
uniprot id: A0A6J3QJ89
uniprot id: A0A6J3QJB9
names: Similarity
messages: Belongs to the NOC2 family.

9739:HASPIN
gene id: 9739:HASPIN
uniprot id: A0A2U4AN91
uniprot id: A0A6J3QNY9
names: Subcellular Location Annotation
messages: Chromosome

9739:GNB1
gene id: 9739:GNB1
uniprot id: A0A2U4BXF9
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

9739:EPHB2
gene id: 9739:EPHB2
uniprot id: A0A6J3Q5E6
names: Subcellular Location Annotation
messages: Membrane

9739:KMT2C
gene id: 9739:KMT2C
uniprot id: A0A2U4AY22
uniprot id: A0A2U4AY25
uniprot id: A0A2U4AY50
uniprot id: A0A6J3RXV9
uniprot id: A0A6J3RXW4
uniprot id: A0A6J3RXX1
uniprot id: A0A6J3RY12
uniprot id: A0A6J3RY24
uniprot id: A0A6J3RYS0
names: Subcellular Location Annotation
messages: Nucleus

9739:IP6K2
gene id: 9739:IP6K2
uniprot id: A0A2U4B1T8
uniprot id: A0A6J3S1M5
uniprot id: A0A6J3S1P8
uniprot id: A0A6J3S2C3
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

9739:HEXD
gene id: 9739:HEXD
uniprot id: A0A2U4C4H3
uniprot id: A0A2U4C4K7
uniprot id: A0A6J3QJH0
uniprot id: A0A6J3QJX6
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

9739:LOC101317415
gene id: 9739:LOC101317415
uniprot id: A0A6J3PT08
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.

9739:SERP2
gene id: 9739:SERP2
uniprot id: A0A6J3QBN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.
messages: Membrane

9739:LOC101329436
gene id: 9739:LOC101329436
uniprot id: A0A6J3QPP9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPCAM family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:LOC109552099
gene id: 9739:LOC109552099
uniprot id: A0A6J3S6E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC7 family.
messages: Nucleus
messages: Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.

9739:LOC101322860
gene id: 9739:LOC101322860
uniprot id: A0A2U4B8T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9739:LOC109548050
gene id: 9739:LOC109548050
uniprot id: A0A2U4AE84
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

9739:SLC2A6
gene id: 9739:SLC2A6
uniprot id: A0A6J3RJG3
uniprot id: A0A6J3RJT9
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

9739:PPP4R3B
gene id: 9739:PPP4R3B
uniprot id: A0A2U3V2X7
uniprot id: A0A2U3V2Z2
uniprot id: A0A6J3PWH4
uniprot id: A0A6J3PWN7
names: Similarity
messages: Belongs to the SMEK family.

9739:NFIL3
gene id: 9739:NFIL3
uniprot id: A0A2U4BF75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts. Represses transcriptional activity of PER1. Represses transcriptional activity of PER2 via the B-site on the promoter. Activates transcription from the interleukin-3 promoter in T-cells. Competes for the same consensus-binding site with PAR DNA-binding factors (DBP, HLF and TEF). Component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock. Protects pro-B cells from programmed cell death.
messages: Belongs to the bZIP family. NFIL3 subfamily.
messages: Homodimer. Binds DNA as a dimer.
messages: Nucleus

9739:MRPL50
gene id: 9739:MRPL50
uniprot id: A0A2U3V693
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL50 family.
messages: Mitochondrion

9739:CCR1
gene id: 9739:CCR1
uniprot id: A0A2U4CAT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

9739:GPR32
gene id: 9739:GPR32
uniprot id: A0A2U4APT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

9739:KCNE4
gene id: 9739:KCNE4
uniprot id: A0A2U3V9V9
names: Similarity
messages: Belongs to the potassium channel KCNE family.

9739:LOC117313284
gene id: 9739:LOC117313284
uniprot id: A0A6J3RS85
names: Subcellular Location Annotation
messages: Membrane

9739:CDC42EP4
gene id: 9739:CDC42EP4
uniprot id: A0A6J3QPF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

9739:EIF5B
gene id: 9739:EIF5B
uniprot id: A0A2U4B0H5
uniprot id: A0A2U4B0H8
uniprot id: A0A2U4B0I1
uniprot id: A0A2U4B0I2
uniprot id: A0A2U4B0I3
uniprot id: A0A2U4B0L2
uniprot id: A0A2U4B0V3
uniprot id: A0A2U4B0V8
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.

9739:HNF4G
gene id: 9739:HNF4G
uniprot id: A0A2U4AJ22
uniprot id: A0A2U4AJ29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Nucleus

9739:DNM3
gene id: 9739:DNM3
uniprot id: A0A6J3R880
uniprot id: A0A6J3R9C2
uniprot id: A0A6J3R9C5
uniprot id: A0A6J3R9C8
uniprot id: A0A6J3RB39
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

9739:ANKRD13D
gene id: 9739:ANKRD13D
uniprot id: A0A6J3RR16
uniprot id: A0A6J3RR90
uniprot id: A0A6J3RRH3
uniprot id: A0A6J3RRX7
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

9739:PKP4
gene id: 9739:PKP4
uniprot id: A0A2U4AAT4
uniprot id: A0A2U4AAZ0
uniprot id: A0A2U4AB54
uniprot id: A0A2U4ABH1
uniprot id: A0A2U4ABH5
uniprot id: A0A6J3RML0
uniprot id: A0A6J3RML4
uniprot id: A0A6J3RMM3
uniprot id: A0A6J3RN00
uniprot id: A0A6J3RNV2
uniprot id: A0A6J3RNV8
uniprot id: A0A6J3RNW3
uniprot id: A0A6J3RP47
names: Similarity
messages: Belongs to the beta-catenin family.

9739:STARD5
gene id: 9739:STARD5
uniprot id: A0A6J3R0R4
names: Function
messages: May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols.

9739:TOR1B
gene id: 9739:TOR1B
uniprot id: A0A6J3RK08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.
messages: Endoplasmic reticulum lumen

9739:DAXX
gene id: 9739:DAXX
uniprot id: A0A6J3S0H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAXX family.
messages: Cytoplasm
messages: PML body
messages: centromere
messages: nucleolus
messages: nucleoplasm

9739:ISYNA1
gene id: 9739:ISYNA1
uniprot id: A0A6J3R4Z1
uniprot id: A0A6J3R5Y3
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

9739:NPR1
gene id: 9739:NPR1
uniprot id: A0A6J3RJF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

9739:UBE2M
gene id: 9739:UBE2M
uniprot id: A0A6J3QET6
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9739:IL36G
gene id: 9739:IL36G
uniprot id: A0A6J3PV65
uniprot id: A0A6J3PV66
uniprot id: A0A6J3PVG7
uniprot id: A0A6J3PVH1
uniprot id: A0A6J3PVW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens.
messages: Belongs to the IL-1 family.
messages: Secreted

9739:LOC101335605
gene id: 9739:LOC101335605
uniprot id: A0A6J3S835
names: Similarity
messages: Belongs to the MORF4 family-associated protein family.

9739:EGR1
gene id: 9739:EGR1
uniprot id: A0A2U3UZH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus
messages: Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death.

9739:PARP6
gene id: 9739:PARP6
uniprot id: A0A2U4CHE6
names: Similarity
messages: Belongs to the ARTD/PARP family.

9739:SERPINF1
gene id: 9739:SERPINF1
uniprot id: A0A6J3QPE7
names: Similarity
messages: Belongs to the serpin family.

9739:CLIC5
gene id: 9739:CLIC5
uniprot id: A0A6J3RZH6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

9739:ESR2
gene id: 9739:ESR2
uniprot id: A0A2U4ABZ9
uniprot id: A0A2U4AC34
uniprot id: A0A6J3QXR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

9739:ITGA6
gene id: 9739:ITGA6
uniprot id: A0A2U4AAE7
uniprot id: A0A2U4AAQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9739:TINAG
gene id: 9739:TINAG
uniprot id: A0A2U4B165
names: Similarity
messages: Belongs to the peptidase C1 family.

9739:POU4F3
gene id: 9739:POU4F3
uniprot id: A0A2U3V0W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

9739:PRKRA
gene id: 9739:PRKRA
uniprot id: A0A6J3RNE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRKRA family.
messages: perinuclear region

9739:TEX10
gene id: 9739:TEX10
uniprot id: A0A2U4CGA5
uniprot id: A0A2U4CGB0
uniprot id: A0A2U4CGB1
names: Similarity
messages: Belongs to the IPI1/TEX10 family.

9739:RTN2
gene id: 9739:RTN2
uniprot id: A0A2U4BBX6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:TFAP2C
gene id: 9739:TFAP2C
uniprot id: A0A6J3Q2F1
uniprot id: A0A6J3Q2G2
uniprot id: A0A6J3Q2L9
uniprot id: A0A6J3Q2R2
uniprot id: A0A6J3Q357
names: Similarity
messages: Belongs to the AP-2 family.

9739:EID2
gene id: 9739:EID2
uniprot id: A0A2U3V4A2
names: Subcellular Location Annotation
messages: Nucleus

9739:RETREG3
gene id: 9739:RETREG3
uniprot id: A0A2U3V3V7
uniprot id: A0A2U4BP42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RETREG family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:CIBAR1
gene id: 9739:CIBAR1
uniprot id: A0A2U3UYX3
uniprot id: A0A6J3Q8M1
uniprot id: A0A6J3Q8Z7
uniprot id: A0A6J3Q905
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CIBAR family.
messages: centriole
messages: cilium basal body

9739:ATP13A2
gene id: 9739:ATP13A2
uniprot id: A0A6J3Q7M2
uniprot id: A0A6J3Q7P2
uniprot id: A0A6J3Q821
uniprot id: A0A6J3Q8G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

9739:MIS18A
gene id: 9739:MIS18A
uniprot id: A0A2U3V0K3
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
messages: centromere

9739:ICMT
gene id: 9739:ICMT
uniprot id: A0A2U4AZX3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
messages: Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:FLOT1
gene id: 9739:FLOT1
uniprot id: A0A6J3RZE4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Endosome
messages: Heterooligomeric complex.
messages: Membrane

9739:CLU
gene id: 9739:CLU
uniprot id: A0A2U4BUR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Antiparallel disulfide-linked heterodimer of an alpha chain and a beta chain. Self-associates and forms higher oligomers.
messages: Belongs to the clusterin family.
messages: Endoplasmic reticulum
messages: Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins.
messages: Membrane
messages: Microsome
messages: Mitochondrion membrane
messages: Nucleus
messages: Secreted
messages: chromaffin granule
messages: cytosol
messages: perinuclear region

9739:TMEM200A
gene id: 9739:TMEM200A
uniprot id: A0A6J3SAM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

9739:SYNM
gene id: 9739:SYNM
uniprot id: A0A2U4C7Q9
uniprot id: A0A2U4C7Z8
names: Similarity
messages: Belongs to the intermediate filament family.

9739:AGBL1
gene id: 9739:AGBL1
uniprot id: A0A6J3QUT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

9739:TTYH2
gene id: 9739:TTYH2
uniprot id: A0A6J3QLC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

9739:PAFAH1B1
gene id: 9739:PAFAH1B1
uniprot id: A0A6J3QPL3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LIS1/nudF family.
messages: Can self-associate. Interacts with DCX, dynein, dynactin, IQGAP1, KATNB1, NDE1, NDEL1, NUDC and RSN. Interacts with DISC1, and this interaction is enhanced by NDEL1. Interacts with DAB1 when DAB1 is phosphorylated in response to RELN/reelin signaling. Component of cytosolic PAF-AH IB, which is composed of PAFAH1B1 (alpha), PAFAH1B2 (beta) and PAFAH1B3 (gamma) subunits. Trimer formation is not essential for the catalytic activity of the enzyme which is contributed solely by the PAFAH1B2 (beta) and PAFAH1B3 (gamma) subunits.
messages: Dimerization mediated by the LisH domain may be required to activate dynein.
messages: Nucleus membrane
messages: Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate. Neuronal migration involves a process called nucleokinesis, whereby migrating cells extend an anterior process into which the nucleus subsequently translocates. During nucleokinesis dynein at the nuclear surface may translocate the nucleus towards the centrosome by exerting force on centrosomal microtubules. Also required for proper activation of Rho GTPases and actin polymerization at the leading edge of locomoting cerebellar neurons and postmigratory hippocampal neurons in response to calcium influx triggered via NMDA receptors. May also play a role in other forms of cell locomotion including the migration of fibroblasts during wound healing. Non-catalytic subunit of an acetylhydrolase complex which inactivates platelet-activating factor (PAF) by removing the acetyl group at the SN-2 position.
messages: centrosome
messages: cytoskeleton
messages: spindle

9739:MPP5
gene id: 9739:MPP5
uniprot id: A0A2U4AA33
uniprot id: A0A2U4AA54
uniprot id: A0A6J3QYJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: Endomembrane system
messages: adherens junction
messages: tight junction

9739:LOC117311565
gene id: 9739:LOC117311565
uniprot id: A0A6J3R243
names: Similarity
messages: Belongs to the TAF11 family.

9739:LOC101322691
gene id: 9739:LOC101322691
uniprot id: A0A6J3RYA2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:FAM72A
gene id: 9739:FAM72A
uniprot id: A0A2U3V1W3
uniprot id: A0A2U4CRP9
uniprot id: A0A2U4CRQ0
uniprot id: A0A6J3R1D2
names: Similarity
messages: Belongs to the FAM72 family.

9739:PLP1
gene id: 9739:PLP1
uniprot id: A0A2U3V885
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

9739:PTPRCAP
gene id: 9739:PTPRCAP
uniprot id: A0A6J3RRB9
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with CD45/PTPRC.
messages: Membrane

9739:PARP14
gene id: 9739:PARP14
uniprot id: A0A6J3RA51
names: Similarity
messages: Belongs to the ARTD/PARP family.

9739:AOC2
gene id: 9739:AOC2
uniprot id: A0A6J3QMX9
uniprot id: A0A6J3QN29
uniprot id: A0A6J3QNH7
uniprot id: A0A6J3QNM6
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

9739:LOC101315568
gene id: 9739:LOC101315568
uniprot id: A0A1K0FUJ2
names: Similarity
messages: Belongs to the globin family.

9739:PTX3
gene id: 9739:PTX3
uniprot id: A0A2U4C8W6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:LOC101337298
gene id: 9739:LOC101337298
uniprot id: A0A6J3RNF4
uniprot id: A0A6J3RNU5
uniprot id: A0A6J3RPB7
uniprot id: A0A6J3RPI2
names: Similarity
messages: Belongs to the cytochrome P450 family.

9739:SLC25A1
gene id: 9739:SLC25A1
uniprot id: A0A6J3PT84
uniprot id: A0A6J3PTP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9739:RDH14
gene id: 9739:RDH14
uniprot id: A0A2U3V413
uniprot id: A0A2U4C007
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9739:MMP24
gene id: 9739:MMP24
uniprot id: A0A6J3Q3W2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

9739:LOC101337569
gene id: 9739:LOC101337569
uniprot id: A0A6J3Q3G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-gamma family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

9739:LOC101332799
gene id: 9739:LOC101332799
uniprot id: A0A6J3QLR6
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

9739:LOC117308127
gene id: 9739:LOC117308127
uniprot id: A0A6J3Q0R1
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

9739:PKDREJ
gene id: 9739:PKDREJ
uniprot id: A0A2U4B673
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:LOC101329910
gene id: 9739:LOC101329910
uniprot id: A0A6J3RKI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eS7 family.
messages: centrosome

9739:LOC101330233
gene id: 9739:LOC101330233
uniprot id: A0A2U4ABG3
uniprot id: A0A6J3QX68
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.
messages: Heterodimer of FNTA and FNTB.

9739:SLC25A34
gene id: 9739:SLC25A34
uniprot id: A0A6J3Q8I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9739:ALDH9A1
gene id: 9739:ALDH9A1
uniprot id: A0A2U3V9M7
uniprot id: A0A2U4B2U0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

9739:TMPRSS4
gene id: 9739:TMPRSS4
uniprot id: A0A6J3RTC7
uniprot id: A0A6J3RTL7
uniprot id: A0A6J3RTM4
uniprot id: A0A6J3RTS1
uniprot id: A0A6J3RTV8
uniprot id: A0A6J3RTW5
uniprot id: A0A6J3RU47
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:DLGAP5
gene id: 9739:DLGAP5
uniprot id: A0A2U4AEE1
uniprot id: A0A2U4AEE4
uniprot id: A0A2U4AEF7
uniprot id: A0A6J3QXW3
names: Similarity
messages: Belongs to the SAPAP family.

9739:SNAP23
gene id: 9739:SNAP23
uniprot id: A0A2U4BCI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Membrane
messages: synaptosome

9739:PRPH2
gene id: 9739:PRPH2
uniprot id: A0A2U3V6H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRPH2/ROM1 family.
messages: Membrane

9739:SLC6A19
gene id: 9739:SLC6A19
uniprot id: A0A6J3R3N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

9739:LOC101316459
gene id: 9739:LOC101316459
uniprot id: A0A2U4BA14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

9739:DEFB128
gene id: 9739:DEFB128
uniprot id: A0A2U3V867
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

9739:SLC27A6
gene id: 9739:SLC27A6
uniprot id: A0A2U4AG00
uniprot id: A0A2U4AG17
uniprot id: A0A2U4AG75
uniprot id: A0A6J3R2T1
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

9739:LOC109547808
gene id: 9739:LOC109547808
uniprot id: A0A2U4A9Z5
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

9739:KAT2A
gene id: 9739:KAT2A
uniprot id: A0A6J3QPQ8
uniprot id: A0A6J3QQA1
uniprot id: A0A6J3QQG0
uniprot id: A0A6J3QQT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. GCN5 subfamily.
messages: Nucleus
messages: centrosome

9739:LOC101334509
gene id: 9739:LOC101334509
uniprot id: A0A6J3RH51
names: Similarity
messages: Belongs to the SPATA31 family.

9739:IL22RA2
gene id: 9739:IL22RA2
uniprot id: A0A2U3V3J1
names: Subcellular Location Annotation
messages: Membrane

9739:GNRH1
gene id: 9739:GNRH1
uniprot id: A0A2U4BUR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GnRH family.
messages: Secreted
messages: Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones.

9739:ZIC4
gene id: 9739:ZIC4
uniprot id: A0A2U3V3F9
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

9739:LOC101331193
gene id: 9739:LOC101331193
uniprot id: A0A6J3R240
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

9739:ZIC3
gene id: 9739:ZIC3
uniprot id: A0A2U3V869
uniprot id: A0A2U4A0P2
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

9739:MMP19
gene id: 9739:MMP19
uniprot id: A0A6J3S784
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

9739:COQ3
gene id: 9739:COQ3
uniprot id: A0A2U3V0H2
uniprot id: A0A2U4AVP0
uniprot id: A0A2U4AW48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Mitochondrion inner membrane
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

9739:UTP18
gene id: 9739:UTP18
uniprot id: A0A2U4C3A6
uniprot id: A0A2U4C3B8
uniprot id: A0A2U4C3H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat UTP18 family.
messages: nucleolus

9739:PPP1R14C
gene id: 9739:PPP1R14C
uniprot id: A0A2U4CPF7
uniprot id: A0A2U4CPG2
uniprot id: A0A2U4CPG5
uniprot id: A0A2U4CPR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP1 inhibitor family.
messages: Inhibitor of PPP1CA.
messages: Membrane

9739:P2RX2
gene id: 9739:P2RX2
uniprot id: A0A6J3PRE2
uniprot id: A0A6J3PRJ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

9739:E2F1
gene id: 9739:E2F1
uniprot id: A0A2U3V325
uniprot id: A0A2U4CLT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

9739:RSPO4
gene id: 9739:RSPO4
uniprot id: A0A6J3Q3V6
names: Similarity
messages: Belongs to the R-spondin family.

9739:RO60
gene id: 9739:RO60
uniprot id: A0A2U4A4R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

9739:KDM5B
gene id: 9739:KDM5B
uniprot id: A0A6J3Q7Y2
uniprot id: A0A6J3Q831
uniprot id: A0A6J3Q880
uniprot id: A0A6J3Q8Y4
uniprot id: A0A6J3Q957
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.

9739:MMP7
gene id: 9739:MMP7
uniprot id: A0A2U4AEA0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

9739:LOC101320926
gene id: 9739:LOC101320926
uniprot id: A0A6J3QRG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

9739:SPOPL
gene id: 9739:SPOPL
uniprot id: A0A2U3V7M8
uniprot id: A0A2U4AJB4
uniprot id: A0A2U4AJI7
names: Similarity
messages: Belongs to the Tdpoz family.

9739:TATDN1
gene id: 9739:TATDN1
uniprot id: A0A2U4B2Y7
uniprot id: A0A2U4B310
uniprot id: A0A2U4B342
uniprot id: A0A2U4B3D9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

9739:GIMAP8
gene id: 9739:GIMAP8
uniprot id: A0A6J3RYJ9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

9739:APPL1
gene id: 9739:APPL1
uniprot id: A0A2U4CCJ6
uniprot id: A0A2U4CCK0
uniprot id: A0A2U4CCN3
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: Nucleus
messages: phagosome
messages: ruffle

9739:LOC117313755
gene id: 9739:LOC117313755
uniprot id: A0A6J3RZA1
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

9739:LOC117312797
gene id: 9739:LOC117312797
uniprot id: A0A6J3RK84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

9739:C8G
gene id: 9739:C8G
uniprot id: A0A6J3RK33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

9739:MAPRE2
gene id: 9739:MAPRE2
uniprot id: A0A2U4AYD5
uniprot id: A0A2U4AYD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

9739:ERO1A
gene id: 9739:ERO1A
uniprot id: A0A2U4AEM9
uniprot id: A0A2U4AEN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane

9739:NDE1
gene id: 9739:NDE1
uniprot id: A0A2U4AT96
uniprot id: A0A2U4ATB0
uniprot id: A0A6J3Q312
uniprot id: A0A6J3Q324
uniprot id: A0A6J3Q3H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: kinetochore
messages: spindle

9739:BRMS1L
gene id: 9739:BRMS1L
uniprot id: A0A2U4AF37
names: Subcellular Location Annotation
messages: Nucleus

9739:RPN2
gene id: 9739:RPN2
uniprot id: A0A2U3V0M8
uniprot id: A0A2U3V0P4
uniprot id: A0A2U4CLJ7
uniprot id: A0A2U4CLJ8
uniprot id: A0A2U4CLK1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SWP1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

9739:UBE2R2
gene id: 9739:UBE2R2
uniprot id: A0A6J3RGG8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9739:UNC5D
gene id: 9739:UNC5D
uniprot id: A0A2U4A729
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

9739:SNX25
gene id: 9739:SNX25
uniprot id: A0A2U4A7G8
uniprot id: A0A2U4A7H1
uniprot id: A0A2U4A7H3
uniprot id: A0A2U4A7H4
uniprot id: A0A2U4A7L4
uniprot id: A0A2U4A899
uniprot id: A0A2U4A8A4
uniprot id: A0A6J3QRI8
uniprot id: A0A6J3QS25
names: Similarity
messages: Belongs to the sorting nexin family.

9739:DUSP7
gene id: 9739:DUSP7
uniprot id: A0A2U4CC17
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

9739:GLI1
gene id: 9739:GLI1
uniprot id: A0A6J3S635
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

9739:GLDC
gene id: 9739:GLDC
uniprot id: A0A2U4BAZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvP family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

9739:MAT2A
gene id: 9739:MAT2A
uniprot id: A0A2U3V0N3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

9739:LOC101316570
gene id: 9739:LOC101316570
uniprot id: A0A2U4AGE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCRQ/QCR8 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 11 subunits. The complex is composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein UQCRFS1, 2 core protein subunits UQCRC1/QCR1 and UQCRC2/QCR2, and 6 low-molecular weight protein subunits UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and subunit 9, the cleavage product of Rieske protein UQCRFS1. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and cytochrome c oxidase (complex IV, CIV), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)). Interacts with UQCC6.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

9739:MAPK9
gene id: 9739:MAPK9
uniprot id: A0A6J3R438
uniprot id: A0A6J3R4C5
uniprot id: A0A6J3R531
uniprot id: A0A6J3R6I7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

9739:ACVR1C
gene id: 9739:ACVR1C
uniprot id: A0A2U4A9Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

9739:SEC11A
gene id: 9739:SEC11A
uniprot id: A0A2U4C7P6
uniprot id: A0A2U4C7Y5
uniprot id: A0A6J3QZZ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Component of the signal peptidase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:CNOT3
gene id: 9739:CNOT3
uniprot id: A0A6J3QHK9
uniprot id: A0A6J3QI17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT2/3/5 family.
messages: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. May be involved in metabolic regulation; may be involved in recruitment of the CCR4-NOT complex to deadenylation target mRNAs involved in energy metabolism. Involved in mitotic progression and regulation of the spindle assembly checkpoint by regulating the stability of MAD1L1 mRNA. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may involve histone deacetylases. Involved in the maintenance of embryonic stem (ES) cell identity.
messages: Nucleus
messages: P-body

9739:LOC101329354
gene id: 9739:LOC101329354
uniprot id: A0A2U4CDL1
names: Subcellular Location Annotation
messages: Membrane

9739:DZIP1L
gene id: 9739:DZIP1L
uniprot id: A0A6J3R8Y8
uniprot id: A0A6J3R9H6
uniprot id: A0A6J3RBP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DZIP C2H2-type zinc-finger protein family.
messages: cilium basal body

9739:HMCES
gene id: 9739:HMCES
uniprot id: A0A2U3V011
names: Function
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.
messages: Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA: forms a stable thiazolidine linkage between a ring-opened abasic site and the alpha-amino and sulfhydryl substituents of its N-terminal catalytic cysteine residue. The HMCES DNA-protein cross-link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endonucleases that are error-prone and would generate mutations and double-strand breaks. Has preference for ssDNA, but can also accommodate double-stranded DNA with 3' or 5' overhang (dsDNA), and dsDNA-ssDNA 3' junction.

9739:DPEP3
gene id: 9739:DPEP3
uniprot id: A0A6J3QGT4
names: Subcellular Location Annotation
messages: Membrane

9739:POLR2C
gene id: 9739:POLR2C
uniprot id: A0A2U3V0L3
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

9739:GPR158
gene id: 9739:GPR158
uniprot id: A0A2U4B6M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9739:HMGN3
gene id: 9739:HMGN3
uniprot id: A0A2U3V1R1
uniprot id: A0A2U3V1S7
uniprot id: A0A2U4AVA2
uniprot id: A0A2U4AVQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

9739:OSGEP
gene id: 9739:OSGEP
uniprot id: A0A2U3V2T4
uniprot id: A0A2U4BC27
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleus

9739:SLC5A2
gene id: 9739:SLC5A2
uniprot id: A0A6J3Q480
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

9739:SEMA6A
gene id: 9739:SEMA6A
uniprot id: A0A2U3V8A3
uniprot id: A0A2U4BT81
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:MTMR1
gene id: 9739:MTMR1
uniprot id: A0A2U4BNQ4
uniprot id: A0A2U4BNQ9
uniprot id: A0A2U4BP29
uniprot id: A0A6J3QTP9
uniprot id: A0A6J3QUK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

9739:FIGN
gene id: 9739:FIGN
uniprot id: A0A2U4ACN5
uniprot id: A0A2U4ACX2
names: Similarity
messages: Belongs to the AAA ATPase family.

9739:GSDMB
gene id: 9739:GSDMB
uniprot id: A0A6J3QNG8
names: Similarity
messages: Belongs to the gasdermin family.

9739:LOC101319114
gene id: 9739:LOC101319114
uniprot id: A0A6J3S3I8
names: Function
names: Similarity
messages: Belongs to the ARPC5 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.

9739:NFE2L3
gene id: 9739:NFE2L3
uniprot id: A0A2U4AMJ5
names: Similarity
messages: Belongs to the bZIP family. CNC subfamily.

9739:TMEM205
gene id: 9739:TMEM205
uniprot id: A0A2U3V204
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM205 family.
messages: Membrane

9739:SNUPN
gene id: 9739:SNUPN
uniprot id: A0A2U3V1V0
uniprot id: A0A2U4CJR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snurportin family.
messages: Cytoplasm
messages: Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.
messages: Nucleus

9739:PADI6
gene id: 9739:PADI6
uniprot id: A0A6J3Q8B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Catalyzes the deimination of arginine residues of proteins.
messages: Cytoplasm

9739:UCN2
gene id: 9739:UCN2
uniprot id: A0A2U4CAT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Binds with high affinity to CRF receptors 2-alpha and 2-beta.
messages: Secreted
messages: Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.

9739:LOC101315484
gene id: 9739:LOC101315484
uniprot id: A0A6J3QC49
names: Subcellular Location Annotation
messages: Cytoplasm

9739:LOC101329080
gene id: 9739:LOC101329080
uniprot id: A0A2U3V7G1
names: Similarity
messages: Belongs to the FAM90 family.

9739:LDAH
gene id: 9739:LDAH
uniprot id: A0A2U3V0H3
uniprot id: A0A2U4C058
uniprot id: A0A6J3PXS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. LDAH family.
messages: Lipid droplet

9739:UNC45A
gene id: 9739:UNC45A
uniprot id: A0A6J3QZW5
uniprot id: A0A6J3R0P2
names: Subcellular Location Annotation
messages: perinuclear region

9739:SLC2A12
gene id: 9739:SLC2A12
uniprot id: A0A6J3SAP7
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

9739:MCHR1
gene id: 9739:MCHR1
uniprot id: A0A6J3S4Q1
uniprot id: A0A6J3S5R1
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Interacts with NCDN.
messages: Membrane

9739:ZKSCAN1
gene id: 9739:ZKSCAN1
uniprot id: A0A2U3V3P7
uniprot id: A0A2U4AYY4
uniprot id: A0A2U4AZ13
names: Subcellular Location Annotation
messages: Nucleus

9739:BCORL1
gene id: 9739:BCORL1
uniprot id: A0A6J3QT08
uniprot id: A0A6J3QTL0
names: Similarity
messages: Belongs to the BCOR family.

9739:ADAMTS7
gene id: 9739:ADAMTS7
uniprot id: A0A6J3QZW6
uniprot id: A0A6J3R0A5
uniprot id: A0A6J3R1J6
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9739:LOC101332089
gene id: 9739:LOC101332089
uniprot id: A0A6J3QYC2
names: Subcellular Location Annotation
messages: Nucleus

9739:KCNA1
gene id: 9739:KCNA1
uniprot id: A0A2U3V6H6
names: Subcellular Location Annotation
messages: Membrane

9739:SLC52A3
gene id: 9739:SLC52A3
uniprot id: A0A2U4CLX2
uniprot id: A0A6J3PZA3
uniprot id: A0A6J3PZH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

9739:RPRD2
gene id: 9739:RPRD2
uniprot id: A0A6J3RN44
names: Similarity
messages: Belongs to the UPF0400 (RTT103) family.

9739:LOC101333906
gene id: 9739:LOC101333906
uniprot id: A0A6J3RSG2
names: Subcellular Location Annotation
messages: Membrane

9739:ACYP1
gene id: 9739:ACYP1
uniprot id: A0A2U3V4E5
uniprot id: A0A2U3V4F8
names: Similarity
messages: Belongs to the acylphosphatase family.

9739:IBSP
gene id: 9739:IBSP
uniprot id: A0A6J3RHD7
names: Function
names: Subcellular Location Annotation
messages: Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment.
messages: Secreted

9739:CABIN1
gene id: 9739:CABIN1
uniprot id: A0A6J3PSR4
uniprot id: A0A6J3PSX7
uniprot id: A0A6J3PTA3
uniprot id: A0A6J3PTB8
uniprot id: A0A6J3PTU6
names: Subcellular Location Annotation
messages: Nucleus

9739:HHIP
gene id: 9739:HHIP
uniprot id: A0A2U3V495
uniprot id: A0A2U3V4B3
names: Caution
names: Similarity
messages: Belongs to the HHIP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:RAMP1
gene id: 9739:RAMP1
uniprot id: A0A2U4ADB6
names: Similarity
messages: Belongs to the RAMP family.

9739:VMA21
gene id: 9739:VMA21
uniprot id: A0A2U3V126
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the V0 complex of the vacuolar ATPase (V-ATPase).
messages: Belongs to the VMA21 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.

9739:LOC101329858
gene id: 9739:LOC101329858
uniprot id: A0A2U3V6X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX17 family.
messages: Mitochondrion intermembrane space

9739:MANBA
gene id: 9739:MANBA
uniprot id: A0A6J3RFJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides.
messages: Lysosome
messages: Monomer.

9739:CTNNA2
gene id: 9739:CTNNA2
uniprot id: A0A2U4BWS2
uniprot id: A0A2U4BWS5
uniprot id: A0A2U4BWS7
uniprot id: A0A2U4BWT0
uniprot id: A0A2U4BWX3
uniprot id: A0A2U4BWZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction

9739:C14H2orf49
gene id: 9739:C14H2orf49
uniprot id: A0A2U4B0V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ashwin family.
messages: Nucleus

9739:EGFR
gene id: 9739:EGFR
uniprot id: A0A6J3RVX1
uniprot id: A0A6J3RVX2
uniprot id: A0A6J3RWE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

9739:MCTS1
gene id: 9739:MCTS1
uniprot id: A0A2U3V7Y3
uniprot id: A0A6J3QTF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCTS1 family.
messages: Cytoplasm

9739:LOC101334300
gene id: 9739:LOC101334300
uniprot id: A0A6J3RT30
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

9739:LOC101322335
gene id: 9739:LOC101322335
uniprot id: A0A6J3PXY4
names: Function
names: Subunit
messages: Interacts with CDC42 (in GTP-bound form). Interacts weakly with RAC1 and not at all with RHOA.
messages: Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages.

9739:SORCS3
gene id: 9739:SORCS3
uniprot id: A0A6J3Q6K3
names: Similarity
messages: Belongs to the VPS10-related sortilin family. SORCS subfamily.

9739:TFAP2E
gene id: 9739:TFAP2E
uniprot id: A0A2U3V0Y9
uniprot id: A0A2U4BKF7
names: Similarity
messages: Belongs to the AP-2 family.

9739:DCAF1
gene id: 9739:DCAF1
uniprot id: A0A2U4CC81
uniprot id: A0A2U4CC84
uniprot id: A0A2U4CC85
uniprot id: A0A2U4CC89
uniprot id: A0A2U4CC90
uniprot id: A0A2U4CC91
uniprot id: A0A6J3S275
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPRBP/DCAF1 family.
messages: Nucleus

9739:HSDL1
gene id: 9739:HSDL1
uniprot id: A0A6J3QBK8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9739:TICAM1
gene id: 9739:TICAM1
uniprot id: A0A6J3R7S4
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer. Found in a multi-helicase-TICAM1 complex at least composed of DHX36, DDX1, DDX21 and TICAM1.
messages: Involved in innate immunity against invading pathogens. Adapter used by TLR3, TLR4 (through TICAM2) and TLR5 to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively. Phosphorylation by TBK1 on the pLxIS motif leads to recruitment and subsequent activation of the transcription factor IRF3 to induce expression of type I interferon and exert a potent immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of pro-inflammatory cytokines.
messages: Mitochondrion
messages: The N-terminal region is essential for activation of the IFNB promoter activity.
messages: autophagosome
messages: cytosol

9739:LOC109551485
gene id: 9739:LOC109551485
uniprot id: A0A6J3RY51
names: Subcellular Location Annotation
messages: Nucleus

9739:ITPRIPL1
gene id: 9739:ITPRIPL1
uniprot id: A0A2U4B0C8
uniprot id: A0A2U4B0F8
uniprot id: A0A2U4B0Q8
uniprot id: A0A6J3PWM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Membrane

9739:CAMTA1
gene id: 9739:CAMTA1
uniprot id: A0A6J3QBG4
uniprot id: A0A6J3QBP2
uniprot id: A0A6J3QBZ4
uniprot id: A0A6J3QCE9
uniprot id: A0A6J3QCF9
names: Similarity
names: Subunit
messages: Belongs to the CAMTA family.
messages: May interact with calmodulin.

9739:NOP14
gene id: 9739:NOP14
uniprot id: A0A6J3RCG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP14 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
messages: nucleolus

9739:FOXK2
gene id: 9739:FOXK2
uniprot id: A0A6J3QND9
names: Subcellular Location Annotation
messages: Nucleus

9739:FAT3
gene id: 9739:FAT3
uniprot id: A0A6J3RU94
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:NSRP1
gene id: 9739:NSRP1
uniprot id: A0A2U4ANH9
uniprot id: A0A2U4ANK7
names: Similarity
messages: Belongs to the NSRP1 family.

9739:ACVR2B
gene id: 9739:ACVR2B
uniprot id: A0A6J3S0T2
uniprot id: A0A6J3S0V3
uniprot id: A0A6J3S1F5
uniprot id: A0A6J3S1X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

9739:GRWD1
gene id: 9739:GRWD1
uniprot id: A0A2U3UZP7
names: Subcellular Location Annotation
messages: Nucleus

9739:TPO
gene id: 9739:TPO
uniprot id: A0A2U3UZM8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:VASN
gene id: 9739:VASN
uniprot id: A0A6J3Q0A6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:SYNGR4
gene id: 9739:SYNGR4
uniprot id: A0A6J3QHP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

9739:TMEM80
gene id: 9739:TMEM80
uniprot id: A0A2U4CMF1
uniprot id: A0A6J3RRW6
uniprot id: A0A6J3RSF0
names: Subcellular Location Annotation
messages: Membrane

9739:LOC109549863
gene id: 9739:LOC109549863
uniprot id: A0A2U4BA07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

9739:LOC117308461
gene id: 9739:LOC117308461
uniprot id: A0A6J3Q642
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

9739:ORC1
gene id: 9739:ORC1
uniprot id: A0A2U4BJV3
uniprot id: A0A6J3S6Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC1 family.
messages: Component of ORC, a complex composed of at least 6 subunits: ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. ORC is regulated in a cell-cycle dependent manner. It is sequentially assembled at the exit from anaphase of mitosis and disassembled as cells enter S phase. Interacts with CDC6 and KAT7/HBO1. Interacts with LRWD1 predominantly during the G1 phase and with less affinity during mitosis, when phosphorylated.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Nucleus

9739:TF
gene id: 9739:TF
uniprot id: A0A2U4B948
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferrin family.
messages: Monomer.
messages: Secreted
messages: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.

9739:TMCO3
gene id: 9739:TMCO3
uniprot id: A0A6J3QB92
uniprot id: A0A6J3QBA0
uniprot id: A0A6J3QBH4
uniprot id: A0A6J3QBI0
uniprot id: A0A6J3QBT4
uniprot id: A0A6J3QBU1
uniprot id: A0A6J3QC05
uniprot id: A0A6J3QC96
names: Subcellular Location Annotation
messages: Membrane

9739:ELOVL2
gene id: 9739:ELOVL2
uniprot id: A0A6J3RYB5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL2 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

9739:CCDC103
gene id: 9739:CCDC103
uniprot id: A0A2U3V6K1
uniprot id: A0A6J3QQT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CCDC103/PR46b family.
messages: Cytoplasm
messages: Dynein-attachment factor required for cilia motility.
messages: Homodimer.
messages: flagellum

9739:BEX5
gene id: 9739:BEX5
uniprot id: A0A2U3VA92
names: Similarity
messages: Belongs to the BEX family.

9739:SIN3A
gene id: 9739:SIN3A
uniprot id: A0A2U4CJ31
uniprot id: A0A2U4CJ52
names: Subcellular Location Annotation
messages: Nucleus

9739:NKG7
gene id: 9739:NKG7
uniprot id: A0A6J3QGH4
uniprot id: A0A6J3QH39
uniprot id: A0A6J3QH74
uniprot id: A0A6J3QHN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

9739:UCP3
gene id: 9739:UCP3
uniprot id: A0A6J3RU78
uniprot id: A0A6J3RUG8
uniprot id: A0A6J3RUN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9739:BARHL2
gene id: 9739:BARHL2
uniprot id: A0A2U3V4K3
names: Subcellular Location Annotation
messages: Nucleus

9739:PNPLA7
gene id: 9739:PNPLA7
uniprot id: A0A6J3RLK7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:MRPL52
gene id: 9739:MRPL52
uniprot id: A0A2U4CFD4
uniprot id: A0A2U4CFD5
uniprot id: A0A2U4CFD6
uniprot id: A0A2U4CFI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL52 family.
messages: Mitochondrion

9739:LOC101329058
gene id: 9739:LOC101329058
uniprot id: A0A6J3QVN9
names: Similarity
messages: Belongs to the serpin family.

9739:VIM
gene id: 9739:VIM
uniprot id: A0A2U3V0C3
names: Similarity
messages: Belongs to the intermediate filament family.

9739:PIR
gene id: 9739:PIR
uniprot id: A0A6J3QTX9
names: Similarity
messages: Belongs to the pirin family.

9739:ZER1
gene id: 9739:ZER1
uniprot id: A0A6J3RJV6
uniprot id: A0A6J3RKT8
names: Similarity
messages: Belongs to the zyg-11 family.

9739:CPSF6
gene id: 9739:CPSF6
uniprot id: A0A2U4CRV0
uniprot id: A0A2U4CRV7
uniprot id: A0A2U4CRW6
uniprot id: A0A2U4CS76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CPSF6/7 family.
messages: Nucleus

9739:GALNT18
gene id: 9739:GALNT18
uniprot id: A0A2U4CE80
uniprot id: A0A6J3RV44
uniprot id: A0A6J3RV62
uniprot id: A0A6J3RV97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9739:LOC101337051
gene id: 9739:LOC101337051
uniprot id: A0A6J3RVV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

9739:LOC101329169
gene id: 9739:LOC101329169
uniprot id: A0A6J3QPE8
names: Similarity
messages: Belongs to the intermediate filament family.

9739:SLC17A1
gene id: 9739:SLC17A1
uniprot id: A0A6J3RYC0
names: Subcellular Location Annotation
messages: Membrane

9739:LOC101337829
gene id: 9739:LOC101337829
uniprot id: A0A6J3QTH0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

9739:LOC101327626
gene id: 9739:LOC101327626
uniprot id: A0A2U3V8A6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space
messages: Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

9739:CHRNA7
gene id: 9739:CHRNA7
uniprot id: A0A2U4CMZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9739:RHBG
gene id: 9739:RHBG
uniprot id: A0A6J3RE54
uniprot id: A0A6J3RE80
uniprot id: A0A6J3RGG6
uniprot id: A0A6J3RGH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

9739:LOC101325830
gene id: 9739:LOC101325830
uniprot id: A0A6J3RAX2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
messages: Homodimer; disulfide-linked.
messages: Membrane

9739:LOC101329554
gene id: 9739:LOC101329554
uniprot id: A0A2U3V664
uniprot id: A0A2U4ADW4
uniprot id: A0A2U4AEE2
uniprot id: A0A6J3RL67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

9739:PHB2
gene id: 9739:PHB2
uniprot id: A0A6J3S7F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

9739:SPNS2
gene id: 9739:SPNS2
uniprot id: A0A6J3QLG0
uniprot id: A0A6J3QLL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

9739:CAPN6
gene id: 9739:CAPN6
uniprot id: A0A2U3UZE2
names: Caution
names: Similarity
messages: Belongs to the peptidase C2 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:MAPK10
gene id: 9739:MAPK10
uniprot id: A0A2U4AMN9
uniprot id: A0A2U4AMP1
uniprot id: A0A2U4AMS7
uniprot id: A0A6J3RE91
uniprot id: A0A6J3REB0
uniprot id: A0A6J3REU0
uniprot id: A0A6J3RGL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

9739:TTYH1
gene id: 9739:TTYH1
uniprot id: A0A6J3QH19
uniprot id: A0A6J3QH48
uniprot id: A0A6J3QHM4
uniprot id: A0A6J3QHM9
uniprot id: A0A6J3QHN4
uniprot id: A0A6J3QHR4
uniprot id: A0A6J3QI65
uniprot id: A0A6J3QI70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable chloride channel.

9739:ENO1
gene id: 9739:ENO1
uniprot id: A0A2U3V1L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

9739:LTA
gene id: 9739:LTA
uniprot id: A0A6J3RZ91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tumor necrosis factor family.
messages: Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo.
messages: Homotrimer, and heterotrimer of either two LTB and one LTA subunits or (less prevalent) two LTA and one LTB subunits. Interacts with TNFRSF14.
messages: Membrane
messages: Secreted

9739:PHKA1
gene id: 9739:PHKA1
uniprot id: A0A2U4B3B6
uniprot id: A0A2U4B3G7
uniprot id: A0A2U4B3R2
uniprot id: A0A6J3QSY4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

9739:LOC101320890
gene id: 9739:LOC101320890
uniprot id: A0A2U4C950
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9739:NPY1R
gene id: 9739:NPY1R
uniprot id: A0A2U3V9C3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9739:LRP12
gene id: 9739:LRP12
uniprot id: A0A2U4BX84
uniprot id: A0A2U4BXD5
uniprot id: A0A6J3Q998
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:SCAMP3
gene id: 9739:SCAMP3
uniprot id: A0A2U3V240
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

9739:CDH15
gene id: 9739:CDH15
uniprot id: A0A6J3QFM0
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

9739:JUND
gene id: 9739:JUND
uniprot id: A0A6J3R5K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

9739:PREB
gene id: 9739:PREB
uniprot id: A0A6J3PXQ9
uniprot id: A0A6J3PY21
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat SEC12 family.
messages: Endoplasmic reticulum membrane
messages: Guanine nucleotide exchange factor that specifically activates the small GTPase SAR1B. Mediates the recruitment of SAR1B and other COPII coat components to endoplasmic reticulum membranes and is therefore required for the formation of COPII transport vesicles from the ER.
messages: Interacts with SAR1B (GDP-bound form). Interacts with MIA2; recruits PREB to endoplasmic reticulum exit sites.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Was first identified based on its probable role in the regulation of pituitary gene transcription. Binds to the prolactin gene (PRL) promoter and seems to activate transcription.

9739:MST1
gene id: 9739:MST1
uniprot id: A0A2U3V1A2
uniprot id: A0A2U4B1Y6
uniprot id: A0A6J3S1X3
names: Caution
names: Similarity
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:P2RX4
gene id: 9739:P2RX4
uniprot id: A0A2U3VA83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

9739:EMX1
gene id: 9739:EMX1
uniprot id: A0A2U3UZI4
uniprot id: A0A2U4C0D1
names: Subcellular Location Annotation
messages: Nucleus

9739:SQLE
gene id: 9739:SQLE
uniprot id: A0A2U4B2W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the squalene monooxygenase family.
messages: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
messages: Endoplasmic reticulum membrane

9739:LTB4R
gene id: 9739:LTB4R
uniprot id: A0A2U4AFI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9739:LOC109547210
gene id: 9739:LOC109547210
uniprot id: A0A6J3QWQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

9739:NAB1
gene id: 9739:NAB1
uniprot id: A0A2U4B1H0
uniprot id: A0A2U4B1H2
uniprot id: A0A2U4B1H6
uniprot id: A0A2U4B1J4
uniprot id: A0A2U4B1J8
uniprot id: A0A2U4B1W5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAB family.
messages: Homomultimers may associate with EGR1 bound to DNA.
messages: Nucleus

9739:PDE8A
gene id: 9739:PDE8A
uniprot id: A0A2U4C7P5
uniprot id: A0A6J3R0S4
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9739:RGS2
gene id: 9739:RGS2
uniprot id: A0A2U4A4Z7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: nucleolus

9739:ENO4
gene id: 9739:ENO4
uniprot id: A0A2U4BR93
names: Similarity
messages: Belongs to the enolase family.

9739:LOC117308527
gene id: 9739:LOC117308527
uniprot id: A0A6J3Q720
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9739:SF3B6
gene id: 9739:SF3B6
uniprot id: A0A2U3UZI9
names: Subcellular Location Annotation
messages: Nucleus

9739:GLP2R
gene id: 9739:GLP2R
uniprot id: A0A2U4C2M2
names: Subcellular Location Annotation
messages: Membrane

9739:MIS12
gene id: 9739:MIS12
uniprot id: A0A2U3V4I1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mis12 family.
messages: Component of the MIS12 complex composed of MIS12, DSN1, NSL1 and PMF1. Also interacts with KNL1, CBX3, CBX5, NDC80 and ZWINT.
messages: kinetochore

9739:CDH8
gene id: 9739:CDH8
uniprot id: A0A2U4BD39
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

9739:EZH2
gene id: 9739:EZH2
uniprot id: A0A2U4B895
uniprot id: A0A2U4B8A5
uniprot id: A0A2U4B8A9
uniprot id: A0A2U4B8B6
uniprot id: A0A2U4B8C1
uniprot id: A0A2U4B8C8
uniprot id: A0A2U4B8H1
uniprot id: A0A2U4B8H7
uniprot id: A0A2U4B8R1
uniprot id: A0A2U4B8S2
uniprot id: A0A6J3RXJ8
names: Subcellular Location Annotation
messages: Nucleus

9739:INPP5B
gene id: 9739:INPP5B
uniprot id: A0A2U4BK95
uniprot id: A0A2U4BKB3
uniprot id: A0A2U4BKE9
uniprot id: A0A2U4BKN3
uniprot id: A0A6J3PU30
uniprot id: A0A6J3PUI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: phagosome membrane

9739:PON3
gene id: 9739:PON3
uniprot id: A0A2U4AQD3
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the paraoxonase family.
messages: Binds 2 calcium ions per subunit.
messages: Glycosylated.

9739:SLC17A3
gene id: 9739:SLC17A3
uniprot id: A0A6J3RZW4
names: Subcellular Location Annotation
messages: Membrane

9739:FAM149B1
gene id: 9739:FAM149B1
uniprot id: A0A2U4BEK4
uniprot id: A0A2U4BEK9
uniprot id: A0A2U4BEL0
uniprot id: A0A2U4BEN6
uniprot id: A0A2U4BEW9
names: Similarity
messages: Belongs to the FAM149 family.

9739:ZP3
gene id: 9739:ZP3
uniprot id: A0A6J3Q1E1
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

9739:AMPD3
gene id: 9739:AMPD3
uniprot id: A0A6J3RV02
uniprot id: A0A6J3RV69
uniprot id: A0A6J3RV76
uniprot id: A0A6J3RV80
uniprot id: A0A6J3RVN9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

9739:RPL26
gene id: 9739:RPL26
uniprot id: A0A2U3V528
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

9739:SPP2
gene id: 9739:SPP2
uniprot id: A0A2U4ADD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPP2 family.
messages: Could coordinate an aspect of bone turnover.
messages: Secreted

9739:MCU
gene id: 9739:MCU
uniprot id: A0A2U4BEM4
uniprot id: A0A2U4BEM5
uniprot id: A0A2U4BEX8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCU (TC 1.A.77) family.
messages: Forms a well-packed pentamer with an overall cylindrical shape. The inner core of the pentamer is formed with the second transmembrane region and the second coiled-coil region: while the transmembrane regions pack into a five-helix bundle having a largely polar pore across the membrane, the coiled-coil outside the membrane forms a pentamer with a hydrophobic core. The inner core is wrapped by the first transmembrane region through contacts between the first and the second transmembrane regions. The second transmembrane is followed by the inner juxtamembrane region (IJMH) that orients at a wide angle relative to the second transmembrane. The two core domains are held together on the periphery by the outer juxtamembrane helix (OJMH).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
messages: Mitochondrion inner membrane

9739:RIC8B
gene id: 9739:RIC8B
uniprot id: A0A2U3ZZ27
uniprot id: A0A2U3ZZ28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synembryn family.
messages: Cytoplasm
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
messages: Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.

9739:LOC101335877
gene id: 9739:LOC101335877
uniprot id: A0A2U3V660
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm
messages: May play a role in lipid transport protein in Schwann cells. May bind cholesterol.
messages: Monomer.

9739:TSC22D3
gene id: 9739:TSC22D3
uniprot id: A0A2U3V934
uniprot id: A0A6J3QRX5
uniprot id: A0A6J3QSC1
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

9739:ONECUT1
gene id: 9739:ONECUT1
uniprot id: A0A6J3R3B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

9739:GLI3
gene id: 9739:GLI3
uniprot id: A0A2U4BSU0
uniprot id: A0A6J3RWN4
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

9739:NT5DC1
gene id: 9739:NT5DC1
uniprot id: A0A2U4AW24
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

9739:FXYD7
gene id: 9739:FXYD7
uniprot id: A0A6J3QER1
uniprot id: A0A6J3QFC1
names: Similarity
messages: Belongs to the FXYD family.

9739:LOC109550912
gene id: 9739:LOC109550912
uniprot id: A0A2U4BV72
names: Similarity
messages: Belongs to the HINT family.

9739:ONECUT2
gene id: 9739:ONECUT2
uniprot id: A0A6J3PU46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

9739:ADGRA3
gene id: 9739:ADGRA3
uniprot id: A0A6J3RDD4
uniprot id: A0A6J3RDY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

9739:RGS9BP
gene id: 9739:RGS9BP
uniprot id: A0A2U4BTT2
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

9739:FAM76A
gene id: 9739:FAM76A
uniprot id: A0A2U3V6I8
uniprot id: A0A2U3V6J6
names: Similarity
messages: Belongs to the FAM76 family.

9739:YIPF1
gene id: 9739:YIPF1
uniprot id: A0A2U3UZN8
uniprot id: A0A2U4BJE0
uniprot id: A0A2U4BJI2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Late endosome membrane
messages: Membrane
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

9739:CFTR
gene id: 9739:CFTR
uniprot id: A0A2U4AHI2
uniprot id: A0A2U4AHJ2
uniprot id: A0A2U4AHJ5
uniprot id: A0A2U4AHU2
uniprot id: A0A2U4AI34
uniprot id: A0A2U4AI40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ABC transporter superfamily. ABCC family. CFTR transporter (TC 3.A.1.202) subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer; does not require oligomerization for channel activity. May form oligomers in the membrane (By similarity). Interacts with SLC26A3, SLC26A6 and NHERF1 (By similarity). Interacts with SHANK2 (By similarity). Interacts with MYO6 (By similarity). Interacts (via C-terminus) with GOPC (via PDZ domain); this promotes CFTR internalization and thereby decreases channel activity. Interacts with SLC4A7 through NHERF1. Found in a complex with MYO5B and RAB11A. Interacts with ANO1. Interacts with SLC26A8 (By similarity). Interacts with AHCYL1; the interaction increases CFTR activity (By similarity). Interacts with CSE1L (By similarity). The core-glycosylated form interacts with GORASP2 (via PDZ GRASP-type 1 domain) in respone to ER stress (By similarity). Interacts with MARCHF2; the interaction leads to CFTR ubiqtuitination and degradation.
messages: Recycling endosome membrane

9739:RNPC3
gene id: 9739:RNPC3
uniprot id: A0A2U4A1Q1
uniprot id: A0A2U4A1Q6
uniprot id: A0A2U4A2M3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the U11/U12 snRNPs that are part of the U12-type spliceosome. Found in a complex with m(7)G-capped U12 snRNA. Interacts with PDCD7.
messages: Nucleus
messages: Participates in pre-mRNA U12-dependent splicing, performed by the minor spliceosome which removes U12-type introns. U12-type introns comprises less than 1% of all non-coding sequences. Binds to the 3'-stem-loop of m(7)G-capped U12 snRNA.

9739:TMEM147
gene id: 9739:TMEM147
uniprot id: A0A6J3QEP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM147 family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane

9739:LOC101330348
gene id: 9739:LOC101330348
uniprot id: A0A6J3R279
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

9739:HOXC11
gene id: 9739:HOXC11
uniprot id: A0A6J3S7R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

9739:DNAH8
gene id: 9739:DNAH8
uniprot id: A0A2U4CJ19
names: Similarity
messages: Belongs to the dynein heavy chain family.

9739:LNPK
gene id: 9739:LNPK
uniprot id: A0A2U4AC30
uniprot id: A0A2U4ACD5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Homodimer; homodimerization requires the C4-type zinc finger motif and decreases during mitosis in a phosphorylation-dependent manner.
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

9739:DRD1
gene id: 9739:DRD1
uniprot id: A0A2U3V7P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
messages: Membrane
messages: dendritic spine

9739:PHC1
gene id: 9739:PHC1
uniprot id: A0A2U4AKV3
uniprot id: A0A2U4ALA6
uniprot id: A0A2U4ALB2
names: Subcellular Location Annotation
messages: Nucleus

9739:HMGB2
gene id: 9739:HMGB2
uniprot id: A0A2U4B3Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

9739:ARG2
gene id: 9739:ARG2
uniprot id: A0A2U4A9U1
uniprot id: A0A6J3QXL5
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

9739:E2F3
gene id: 9739:E2F3
uniprot id: A0A6J3RYX2
uniprot id: A0A6J3RZ47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

9739:BTN1A1
gene id: 9739:BTN1A1
uniprot id: A0A2U4C4V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

9739:GPC5
gene id: 9739:GPC5
uniprot id: A0A2U4A644
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

9739:VPS52
gene id: 9739:VPS52
uniprot id: A0A6J3S0C1
uniprot id: A0A6J3S0D6
uniprot id: A0A6J3S0Y8
names: Similarity
messages: Belongs to the VPS52 family.

9739:STARD13
gene id: 9739:STARD13
uniprot id: A0A2U4BGL1
names: Subcellular Location Annotation
messages: Cytoplasm

9739:TMC7
gene id: 9739:TMC7
uniprot id: A0A2U4A935
uniprot id: A0A2U4A966
uniprot id: A0A2U4A9T1
uniprot id: A0A2U4A9T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

9739:WDFY2
gene id: 9739:WDFY2
uniprot id: A0A2U4BG71
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

9739:TGFBR1
gene id: 9739:TGFBR1
uniprot id: A0A2U4CGK0
uniprot id: A0A2U4CGL0
uniprot id: A0A2U4CGL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

9739:LOC101336502
gene id: 9739:LOC101336502
uniprot id: A0A6J3RVE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSU72 phosphatase family.
messages: Nucleus
messages: Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination.

9739:CALY
gene id: 9739:CALY
uniprot id: A0A6J3Q753
uniprot id: A0A6J3Q7J9
names: Similarity
messages: Belongs to the NSG family.

9739:LPCAT2
gene id: 9739:LPCAT2
uniprot id: A0A6J3QCH7
uniprot id: A0A6J3QD35
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

9739:DGKI
gene id: 9739:DGKI
uniprot id: A0A2U4CJQ5
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

9739:MLH1
gene id: 9739:MLH1
uniprot id: A0A2U4CAI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: Nucleus

9739:SPOCK2
gene id: 9739:SPOCK2
uniprot id: A0A6J3Q6K5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:LOC101333055
gene id: 9739:LOC101333055
uniprot id: A0A6J3RAZ6
names: Subcellular Location Annotation
messages: Membrane

9739:LOC101318737
gene id: 9739:LOC101318737
uniprot id: A0A2U3V795
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

9739:RPS15A
gene id: 9739:RPS15A
uniprot id: A0A2U4A9F7
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

9739:UNC5B
gene id: 9739:UNC5B
uniprot id: A0A6J3Q5M5
uniprot id: A0A6J3Q5V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

9739:SCARF2
gene id: 9739:SCARF2
uniprot id: A0A6J3PTJ4
uniprot id: A0A6J3PU43
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:MRPL51
gene id: 9739:MRPL51
uniprot id: A0A2U3V5T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL51 family.
messages: Mitochondrion

9739:ZSCAN29
gene id: 9739:ZSCAN29
uniprot id: A0A2U3V996
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

9739:CDH22
gene id: 9739:CDH22
uniprot id: A0A6J3Q0Q9
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

9739:SERINC2
gene id: 9739:SERINC2
uniprot id: A0A6J3PY26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

9739:NBL1
gene id: 9739:NBL1
uniprot id: A0A2U3V487
uniprot id: A0A2U4A0J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

9739:CSGALNACT1
gene id: 9739:CSGALNACT1
uniprot id: A0A2U4A817
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

9739:SELE
gene id: 9739:SELE
uniprot id: A0A2U3ZZT4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selectin/LECAM family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:PSENEN
gene id: 9739:PSENEN
uniprot id: A0A2U3V3Y9
uniprot id: A0A2U4BUE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEN-2 family.
messages: Golgi stack membrane
messages: Membrane

9739:LOC117310365
gene id: 9739:LOC117310365
uniprot id: A0A6J3QV04
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:B3GLCT
gene id: 9739:B3GLCT
uniprot id: A0A2U4BGJ9
uniprot id: A0A2U4BGN0
names: Subcellular Location Annotation
messages: Membrane

9739:THRAP3
gene id: 9739:THRAP3
uniprot id: A0A2U3V5M3
uniprot id: A0A2U4BKD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCLAF1/THRAP3 family.
messages: Belongs to the CASC3 family.
messages: Cytoplasm
messages: Nucleus

9739:CLEC16A
gene id: 9739:CLEC16A
uniprot id: A0A6J3Q2R8
uniprot id: A0A6J3Q2T3
uniprot id: A0A6J3Q302
uniprot id: A0A6J3Q316
uniprot id: A0A6J3Q320
uniprot id: A0A6J3Q3G9
names: Similarity
messages: Belongs to the CLEC16A/gop-1 family.

9739:LOC117307867
gene id: 9739:LOC117307867
uniprot id: A0A2U3V4R9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit F family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm
messages: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.

9739:NES
gene id: 9739:NES
uniprot id: A0A6J3RE23
names: Similarity
messages: Belongs to the intermediate filament family.

9739:ABCC6
gene id: 9739:ABCC6
uniprot id: A0A2U4AT92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

9739:PTK6
gene id: 9739:PTK6
uniprot id: A0A6J3Q242
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

9739:RIOX2
gene id: 9739:RIOX2
uniprot id: A0A2U4AAB6
uniprot id: A0A6J3RAC1
uniprot id: A0A6J3RAL9
uniprot id: A0A6J3RB31
uniprot id: A0A6J3RBE0
uniprot id: A0A6J3RD42
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROX family.
messages: Belongs to the ROX family. MINA53 subfamily.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Nucleus
messages: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.

9739:CXCL12
gene id: 9739:CXCL12
uniprot id: A0A2U3V0G0
uniprot id: A0A2U3V0T3
uniprot id: A0A2U4B855
names: Similarity
messages: Belongs to the intercrine alpha (chemokine CxC) family.

9739:LOC117309029
gene id: 9739:LOC117309029
uniprot id: A0A6J3QDU3
uniprot id: A0A6J3QDU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

9739:NCAPH2
gene id: 9739:NCAPH2
uniprot id: A0A6J3S3V0
uniprot id: A0A6J3S408
uniprot id: A0A6J3S459
uniprot id: A0A6J3S4V7
uniprot id: A0A6J3S552
names: Similarity
messages: Belongs to the CND2 H2 (condensin-2 subunit 2) family.

9739:SLA
gene id: 9739:SLA
uniprot id: A0A2U4B2Z1
names: Subcellular Location Annotation
messages: Cytoplasm

9739:RXRB
gene id: 9739:RXRB
uniprot id: A0A6J3S0C5
uniprot id: A0A6J3S0E8
uniprot id: A0A6J3S0I2
uniprot id: A0A6J3S1E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Nucleus

9739:UPK1A
gene id: 9739:UPK1A
uniprot id: A0A6J3QEN1
uniprot id: A0A6J3QEP1
uniprot id: A0A6J3QF89
names: Subcellular Location Annotation
messages: Membrane

9739:ALG12
gene id: 9739:ALG12
uniprot id: A0A2U4B636
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:TUBAL3
gene id: 9739:TUBAL3
uniprot id: A0A6J3QUW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

9739:MED7
gene id: 9739:MED7
uniprot id: A0A2U3V7W6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 7 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
messages: Component of the Mediator complex.
messages: Nucleus

9739:PLIN1
gene id: 9739:PLIN1
uniprot id: A0A6J3QZU1
names: Similarity
messages: Belongs to the perilipin family.

9739:WNT10A
gene id: 9739:WNT10A
uniprot id: A0A6J3RLR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9739:TARBP2
gene id: 9739:TARBP2
uniprot id: A0A6J3S628
uniprot id: A0A6J3S7E9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TARBP2 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1.
messages: Self-associates. Component of the RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Note that the trimeric RLC/miRLC is also referred to as RISC. Interacts with EIF2AK2/PKR and inhibits its protein kinase activity. Interacts with DHX9 and PRKRA. Interacts with DICER1, AGO2, MOV10, EIF6 and RPL7A (60S ribosome subunit); they form a large RNA-induced silencing complex (RISC).
messages: perinuclear region

9739:MLN
gene id: 9739:MLN
uniprot id: A0A6J3RYA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the motilin family.
messages: Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle.
messages: Secreted

9739:TOP1
gene id: 9739:TOP1
uniprot id: A0A2U3UYS8
uniprot id: A0A6J3Q3W1
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

9739:GLUL
gene id: 9739:GLUL
uniprot id: A0A2U3ZZ00
uniprot id: A0A2U3ZZ15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamine synthetase family.
messages: Cell membrane
messages: Membrane
messages: Microsome
messages: Mitochondrion

9739:CSF2
gene id: 9739:CSF2
uniprot id: A0A6J3R4X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GM-CSF family.
messages: Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.
messages: Monomer. The signaling GM-CSF receptor complex is a dodecamer of two head-to-head hexamers of two alpha, two beta, and two ligand subunits.
messages: Secreted

9739:PIGF
gene id: 9739:PIGF
uniprot id: A0A6J3PWN1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:ACP5
gene id: 9739:ACP5
uniprot id: I1E388
names: Cofactor
messages: Binds 2 iron ions per subunit.

9739:ACTRT1
gene id: 9739:ACTRT1
uniprot id: A0A2U4CHY9
names: Similarity
messages: Belongs to the actin family.

9739:CHRNA3
gene id: 9739:CHRNA3
uniprot id: A0A2U4CKD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9739:UNC93A
gene id: 9739:UNC93A
uniprot id: A0A6J3S8H0
uniprot id: A0A6J3S8T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

9739:ACTC1
gene id: 9739:ACTC1
uniprot id: A0A6J3QY52
names: Similarity
messages: Belongs to the actin family.

9739:RNF4
gene id: 9739:RNF4
uniprot id: A0A2U4CN97
uniprot id: A0A2U4CN98
uniprot id: A0A2U4CNA4
uniprot id: A0A6J3RC92
names: Subcellular Location Annotation
messages: Nucleus

9739:CBFB
gene id: 9739:CBFB
uniprot id: A0A2U3UYW0
uniprot id: A0A2U3UZ91
uniprot id: A0A6J3QJ14
uniprot id: A0A6J3QJG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF-beta family.
messages: Membrane
messages: Nucleus

9739:TSPYL6
gene id: 9739:TSPYL6
uniprot id: A0A2U4BXP9
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9739:LOC117308555
gene id: 9739:LOC117308555
uniprot id: A0A6J3Q7Q6
uniprot id: A0A6J3Q850
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Exhibits ester hydrolase activity on the substrate p-nitrophenyl acetate.
messages: Monomer.
messages: Nucleus

9739:TRAPPC3
gene id: 9739:TRAPPC3
uniprot id: A0A2U3V598
uniprot id: A0A6J3PUV3
uniprot id: A0A6J3PUW4
uniprot id: A0A6J3PV77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Homodimer.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: cis-Golgi network

9739:PELI3
gene id: 9739:PELI3
uniprot id: A0A6J3RQV0
uniprot id: A0A6J3RR92
uniprot id: A0A6J3RRQ2
uniprot id: A0A6J3RRR5
names: Function
names: Similarity
messages: Belongs to the pellino family.
messages: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.

9739:FABP3
gene id: 9739:FABP3
uniprot id: A0A6J3PYE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm

9739:RTN1
gene id: 9739:RTN1
uniprot id: A0A2U4AFV1
uniprot id: A0A2U4AG14
uniprot id: A0A2U4AGA8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:CUTC
gene id: 9739:CUTC
uniprot id: A0A2U3V7N9
uniprot id: A0A2U4BQ66
uniprot id: A0A6J3Q5W9
uniprot id: A0A6J3Q5X2
uniprot id: A0A6J3Q6A1
uniprot id: A0A6J3Q6M8
uniprot id: A0A6J3Q6N0
uniprot id: A0A6J3Q6N5
names: Similarity
messages: Belongs to the CutC family.

9739:LOC117312103
gene id: 9739:LOC117312103
uniprot id: A0A6J3R9J5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

9739:ZSCAN20
gene id: 9739:ZSCAN20
uniprot id: A0A2U4BKH5
uniprot id: A0A2U4BKI8
uniprot id: A0A2U4BKV6
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

9739:ZFYVE28
gene id: 9739:ZFYVE28
uniprot id: A0A6J3RD58
names: Similarity
messages: Belongs to the lst-2 family.

9739:CKM
gene id: 9739:CKM
uniprot id: A0A6J3QEV7
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

9739:FAS
gene id: 9739:FAS
uniprot id: A0A2U4BTJ7
uniprot id: A0A2U4BUZ0
uniprot id: A0A2U4BV11
uniprot id: A0A2U4BV76
uniprot id: A0A2U4BVF7
uniprot id: A0A2U4BVN7
uniprot id: A0A6J3Q5C1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

9739:CTSK
gene id: 9739:CTSK
uniprot id: A0A2U3V3K8
uniprot id: A0A2U4A2E9
uniprot id: A0A2U4A2F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

9739:POLR3D
gene id: 9739:POLR3D
uniprot id: A0A2U3V702
names: Subcellular Location Annotation
messages: Nucleus

9739:PIK3C2B
gene id: 9739:PIK3C2B
uniprot id: A0A6J3R155
uniprot id: A0A6J3R161
uniprot id: A0A6J3R172
uniprot id: A0A6J3R176
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

9739:POLR1F
gene id: 9739:POLR1F
uniprot id: A0A2U3V9L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA43 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

9739:MVP
gene id: 9739:MVP
uniprot id: A0A6J3Q4P4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates IFNG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.

9739:LAMB1
gene id: 9739:LAMB1
uniprot id: A0A6J3RWP3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

9739:TRIP13
gene id: 9739:TRIP13
uniprot id: A0A6J3R1R8
uniprot id: A0A6J3R202
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AAA ATPase family. PCH2 subfamily.
messages: Nucleus
messages: Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways.
messages: Specifically interacts with the ligand binding domain of the thyroid receptor (TR). This interaction does not require the presence of thyroid hormone for its interaction. Interacts with proteasome subunit PSMA8; to participate in meiosis progression during spermatogenesis.

9739:TLR2
gene id: 9739:TLR2
uniprot id: A0A2U4AML7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
messages: Membrane

9739:FTMT
gene id: 9739:FTMT
uniprot id: A0A2U4BTF6
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

9739:ADAM19
gene id: 9739:ADAM19
uniprot id: A0A2U4AHV5
uniprot id: A0A6J3R3P3
uniprot id: A0A6J3R4B6
uniprot id: A0A6J3R4L9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:FAM135A
gene id: 9739:FAM135A
uniprot id: A0A6J3S8A9
uniprot id: A0A6J3S8B4
uniprot id: A0A6J3S8K0
uniprot id: A0A6J3S8W6
uniprot id: A0A6J3S8X1
uniprot id: A0A6J3S9Y5
uniprot id: A0A6J3SA06
uniprot id: A0A6J3SA10
uniprot id: A0A6J3SA14
names: Similarity
messages: Belongs to the FAM135 family.

9739:ZIC2
gene id: 9739:ZIC2
uniprot id: A0A2U4A636
uniprot id: A0A6J3QAY4
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

9739:LOC101334436
gene id: 9739:LOC101334436
uniprot id: A0A6J3QC85
names: Similarity
messages: Belongs to the BolA/IbaG family.

9739:ENTPD3
gene id: 9739:ENTPD3
uniprot id: A0A2U4CAH6
uniprot id: A0A2U4CAJ6
uniprot id: A0A2U4CAQ1
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

9739:LDLRAD4
gene id: 9739:LDLRAD4
uniprot id: A0A2U4A5P2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMEPA1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:IL1RAPL2
gene id: 9739:IL1RAPL2
uniprot id: A0A2U4CHR5
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

9739:CUL5
gene id: 9739:CUL5
uniprot id: A0A2U3V2N5
uniprot id: A0A6J3RU45
uniprot id: A0A6J3RUC0
names: Similarity
messages: Belongs to the cullin family.

9739:AP3M2
gene id: 9739:AP3M2
uniprot id: A0A2U4A836
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

9739:AP1B1
gene id: 9739:AP1B1
uniprot id: A0A6J3PSD8
uniprot id: A0A6J3PSS5
uniprot id: A0A6J3PST6
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

9739:ALOX5AP
gene id: 9739:ALOX5AP
uniprot id: A0A6J3QAI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:PPP1CC
gene id: 9739:PPP1CC
uniprot id: A0A6J3PS46
uniprot id: A0A6J3RF26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: nucleolus
messages: nucleoplasm

9739:IP6K3
gene id: 9739:IP6K3
uniprot id: A0A2U3V6B6
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

9739:GNB2
gene id: 9739:GNB2
uniprot id: A0A6J3Q2X2
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

9739:RRH
gene id: 9739:RRH
uniprot id: A0A2U4AQX3
uniprot id: A0A2U4AQY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

9739:MC3R
gene id: 9739:MC3R
uniprot id: A0A2U3V8A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane

9739:TMEM231
gene id: 9739:TMEM231
uniprot id: A0A2U3V088
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM231 family.
messages: Membrane
messages: Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling.
messages: cilium membrane

9739:KCNH4
gene id: 9739:KCNH4
uniprot id: A0A6J3QNJ1
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

9739:VEGFA
gene id: 9739:VEGFA
uniprot id: A0A6J3RZK8
uniprot id: A0A6J3RZM2
uniprot id: A0A6J3RZT3
uniprot id: A0A6J3S013
uniprot id: A0A6J3S0N6
uniprot id: A0A6J3S0P2
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

9739:FAM3C
gene id: 9739:FAM3C
uniprot id: A0A2U3V3T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

9739:SLC22A5
gene id: 9739:SLC22A5
uniprot id: A0A2U3V886
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Basal cell membrane
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
messages: Interacts with PDZK1.

9739:MYO3B
gene id: 9739:MYO3B
uniprot id: A0A2U4AA10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: In the C-terminal section; belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: cytoskeleton

9739:LOC101325081
gene id: 9739:LOC101325081
uniprot id: A0A2U4A691
names: Similarity
messages: Belongs to the MORF4 family-associated protein family.

9739:UTP15
gene id: 9739:UTP15
uniprot id: A0A2U4AWR0
uniprot id: A0A2U4AX89
names: Subcellular Location Annotation
messages: nucleolus

9739:FER1L5
gene id: 9739:FER1L5
uniprot id: A0A6J3PX23
names: Similarity
messages: Belongs to the ferlin family.

9739:CHD4
gene id: 9739:CHD4
uniprot id: A0A6J3S7I5
uniprot id: A0A6J3S7J0
uniprot id: A0A6J3S7V4
uniprot id: A0A6J3S846
uniprot id: A0A6J3S852
uniprot id: A0A6J3S946
uniprot id: A0A6J3S955
uniprot id: A0A6J3S9B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

9739:LOC109552317
gene id: 9739:LOC109552317
uniprot id: A0A6J3RUE2
names: Similarity
messages: Belongs to the UQCRH/QCR6 family.

9739:GMNN
gene id: 9739:GMNN
uniprot id: A0A2U3V3M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the geminin family.
messages: Nucleus

9739:DHCR7
gene id: 9739:DHCR7
uniprot id: A0A6J3RRP2
uniprot id: A0A6J3RRY0
uniprot id: A0A6J3RS88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

9739:FGFR3
gene id: 9739:FGFR3
uniprot id: A0A6J3RCA4
uniprot id: A0A6J3RCA9
uniprot id: A0A6J3RCU5
uniprot id: A0A6J3RD24
uniprot id: A0A6J3REN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Cell membrane
messages: Membrane

9739:PSMA6
gene id: 9739:PSMA6
uniprot id: A0A2U3V414
uniprot id: A0A2U4AF46
uniprot id: A0A2U4AF97
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

9739:REEP4
gene id: 9739:REEP4
uniprot id: A0A6J3RFQ8
uniprot id: A0A6J3RFV1
uniprot id: A0A6J3RGI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

9739:FOXP2
gene id: 9739:FOXP2
uniprot id: A0A2U4AI81
names: Subcellular Location Annotation
messages: Nucleus

9739:VXN
gene id: 9739:VXN
uniprot id: A0A2U3V849
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vexin family.
messages: Cell membrane
messages: Membrane
messages: Nucleus

9739:SSTR2
gene id: 9739:SSTR2
uniprot id: A0A2U3UZW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer and heterodimer with SSTR3 and SSTR5. Heterodimerization with SSTR3 inactivates SSTR3 receptor function. Heterodimerization with SSTR5 is enhanced by agonist stimulation of SSTR2 and increases SSTR2 cell growth inhibition activity. Following agonist stimulation, homodimers dissociate into monomers which is required for receptor internalization. Interacts with beta-arrestin; this interaction is necessary for receptor internalization and is destabilized by heterodimerization with SSTR5 which results in increased recycling of SSTR2 to the cell surface. Interacts (via C-terminus) with SHANK1 (via PDZ domain).
messages: Membrane
messages: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

9739:SLC12A2
gene id: 9739:SLC12A2
uniprot id: A0A2U4AG12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

9739:LOC101338397
gene id: 9739:LOC101338397
uniprot id: A0A6J3Q0A7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

9739:CHPF
gene id: 9739:CHPF
uniprot id: A0A6J3RMZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

9739:CLCN5
gene id: 9739:CLCN5
uniprot id: A0A2U4C162
uniprot id: A0A6J3QSY1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-5/CLCN5 subfamily.
messages: Cell membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Interacts with NEDD4 and NEDD4L.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:THRB
gene id: 9739:THRB
uniprot id: A0A2U4CFD9
uniprot id: A0A2U4CFF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

9739:ETS2
gene id: 9739:ETS2
uniprot id: A0A6J3RAV9
uniprot id: A0A6J3RB40
uniprot id: A0A6J3RBU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus
messages: Transcription factor.

9739:LOC117309737
gene id: 9739:LOC117309737
uniprot id: A0A6J3QPZ3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

9739:COG8
gene id: 9739:COG8
uniprot id: A0A2U3V457
uniprot id: A0A6J3QJ29
uniprot id: A0A6J3QJH8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COG8 family.
messages: Belongs to the polypeptide deformylase family.
messages: Component of the conserved oligomeric Golgi complex which is composed of eight different subunits and is required for normal Golgi morphology and localization.
messages: Golgi apparatus membrane
messages: Membrane

9739:CIRBP
gene id: 9739:CIRBP
uniprot id: A0A6J3R7M7
uniprot id: A0A6J3R7S7
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with EIF4G1. Associates with ribosomes.
messages: nucleoplasm

9739:TMEM30A
gene id: 9739:TMEM30A
uniprot id: A0A2U4AV74
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

9739:LOC101326029
gene id: 9739:LOC101326029
uniprot id: A0A2U4CBD6
uniprot id: A0A2U4CBE0
uniprot id: A0A6J3S6B7
uniprot id: A0A6J3S7R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

9739:TWIST1
gene id: 9739:TWIST1
uniprot id: A0A2U4B1E9
names: Function
messages: Acts as a transcriptional regulator. Inhibits myogenesis by sequestrating E proteins, inhibiting trans-activation by MEF2, and inhibiting DNA-binding by MYOD1 through physical interaction. This interaction probably involves the basic domains of both proteins. Also represses expression of pro-inflammatory cytokines such as TNFA and IL1B. Regulates cranial suture patterning and fusion. Activates transcription as a heterodimer with E proteins. Regulates gene expression differentially, depending on dimer composition. Homodimers induce expression of FGFR2 and POSTN while heterodimers repress FGFR2 and POSTN expression and induce THBS1 expression. Heterodimerization is also required for osteoblast differentiation. Represses the activity of the circadian transcriptional activator: NPAS2-BMAL1 heterodimer.

9739:LOC101339654
gene id: 9739:LOC101339654
uniprot id: A0A6J3RXB2
names: Subcellular Location Annotation
messages: Nucleus

9739:LOC101334388
gene id: 9739:LOC101334388
uniprot id: A0A6J3RXX2
names: Similarity
messages: Belongs to the peptidase A1 family.

9739:AGTPBP1
gene id: 9739:AGTPBP1
uniprot id: A0A2U4BRU9
uniprot id: A0A2U4BRW3
uniprot id: A0A6J3RGQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

9739:TEAD3
gene id: 9739:TEAD3
uniprot id: A0A2U4CJ03
uniprot id: A0A2U4CJ04
uniprot id: A0A6J3S055
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.

9739:NDUFA12
gene id: 9739:NDUFA12
uniprot id: A0A2U3ZZH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA12 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9739:PTPN13
gene id: 9739:PTPN13
uniprot id: A0A2U4AMP5
uniprot id: A0A2U4AMP7
uniprot id: A0A2U4AMQ0
uniprot id: A0A2U4AMQ2
uniprot id: A0A2U4AMQ5
uniprot id: A0A2U4AMQ6
uniprot id: A0A2U4AMR2
uniprot id: A0A2U4AMT3
uniprot id: A0A2U4AN36
uniprot id: A0A2U4AN41
uniprot id: A0A6J3REB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: Regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling.
messages: cytoskeleton

9739:RAB11FIP3
gene id: 9739:RAB11FIP3
uniprot id: A0A6J3Q0Y7
uniprot id: A0A6J3Q115
uniprot id: A0A6J3Q183
uniprot id: A0A6J3Q1K0
uniprot id: A0A6J3Q1K5
names: Subcellular Location Annotation
messages: Cleavage furrow
messages: Endosome membrane
messages: Membrane
messages: Midbody
messages: Recycling endosome membrane

9739:FMNL3
gene id: 9739:FMNL3
uniprot id: A0A6J3S6L8
uniprot id: A0A6J3S6V8
uniprot id: A0A6J3S747
uniprot id: A0A6J3S800
uniprot id: A0A6J3S8D1
names: Similarity
messages: Belongs to the formin homology family.

9739:SRP68
gene id: 9739:SRP68
uniprot id: A0A2U3UYI2
uniprot id: A0A2U4BM77
uniprot id: A0A2U4BMC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP68 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER.
messages: Cytoplasm
messages: nucleolus

9739:ELP3
gene id: 9739:ELP3
uniprot id: A0A6J3RG98
uniprot id: A0A6J3RHP6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.

9739:C8H11orf1
gene id: 9739:C8H11orf1
uniprot id: A0A2U3V7I7
names: Function
names: Subcellular Location Annotation
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.
messages: cilium axoneme

9739:KMT2D
gene id: 9739:KMT2D
uniprot id: A0A6J3S6P7
uniprot id: A0A6J3S6Q3
uniprot id: A0A6J3S6Y8
uniprot id: A0A6J3S6Z5
uniprot id: A0A6J3S700
uniprot id: A0A6J3S781
uniprot id: A0A6J3S786
uniprot id: A0A6J3S830
uniprot id: A0A6J3S836
uniprot id: A0A6J3S8G0
uniprot id: A0A6J3S8G5
names: Subcellular Location Annotation
messages: Nucleus

9739:INHBE
gene id: 9739:INHBE
uniprot id: A0A6J3S3L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

9739:ABCC4
gene id: 9739:ABCC4
uniprot id: A0A6J3QAI0
uniprot id: A0A6J3QB94
names: Subcellular Location Annotation
messages: Membrane

9739:ROCK1
gene id: 9739:ROCK1
uniprot id: A0A2U4AYR8
uniprot id: A0A2U4AYS1
uniprot id: A0A2U4AZ74
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by RHOA binding. Inhibited by Y-27632.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cytoplasm
messages: Homodimer.
messages: Membrane
messages: Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.

9739:ADRA2C
gene id: 9739:ADRA2C
uniprot id: A0A2U3V552
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9739:HS3ST6
gene id: 9739:HS3ST6
uniprot id: A0A6J3PZB4
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9739:LOC117308930
gene id: 9739:LOC117308930
uniprot id: A0A6J3QCM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Membrane
messages: Microsome membrane

9739:FBXL5
gene id: 9739:FBXL5
uniprot id: A0A2U4ASU0
uniprot id: A0A6J3RE47
names: Subcellular Location Annotation
messages: perinuclear region

9739:ABCC3
gene id: 9739:ABCC3
uniprot id: A0A6J3QNQ2
uniprot id: A0A6J3QNU2
uniprot id: A0A6J3QPA2
uniprot id: A0A6J3QPJ4
uniprot id: A0A6J3QPJ9
uniprot id: A0A6J3QPY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

9739:FANCM
gene id: 9739:FANCM
uniprot id: A0A2U4AEW3
uniprot id: A0A2U4AEW7
uniprot id: A0A2U4AF25
uniprot id: A0A2U4AFD2
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.

9739:STX4
gene id: 9739:STX4
uniprot id: A0A6J3PZF7
uniprot id: A0A6J3PZI0
names: Similarity
messages: Belongs to the syntaxin family.

9739:PRPF3
gene id: 9739:PRPF3
uniprot id: A0A2U4A328
uniprot id: A0A2U4A329
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).

9739:SPOP
gene id: 9739:SPOP
uniprot id: A0A2U4AHV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tdpoz family.
messages: Nucleus speckle

9739:CORO6
gene id: 9739:CORO6
uniprot id: A0A6J3QMV2
uniprot id: A0A6J3QNY4
names: Similarity
messages: Belongs to the WD repeat coronin family.

9739:MPP3
gene id: 9739:MPP3
uniprot id: A0A6J3QMY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane

9739:LOC117313826
gene id: 9739:LOC117313826
uniprot id: A0A6J3RZA6
names: Similarity
messages: Belongs to the heat shock protein 70 family.

9739:LDB3
gene id: 9739:LDB3
uniprot id: A0A2U4AJZ1
uniprot id: A0A2U4AJZ5
uniprot id: A0A2U4AJZ8
uniprot id: A0A2U4AK56
uniprot id: A0A6J3Q6B2
uniprot id: A0A6J3Q6C1
uniprot id: A0A6J3Q746
uniprot id: A0A6J3Q755
names: Subcellular Location Annotation
messages: Z line

9739:SLIT3
gene id: 9739:SLIT3
uniprot id: A0A6J3R3S4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9739:LOC101325870
gene id: 9739:LOC101325870
uniprot id: A0A6J3S9Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

9739:LOC101315521
gene id: 9739:LOC101315521
uniprot id: A0A6J3RJ89
names: Similarity
messages: Belongs to the SPATA31 family.

9739:KDM6B
gene id: 9739:KDM6B
uniprot id: A0A6J3QQ23
uniprot id: A0A6J3QQ68
uniprot id: A0A6J3QQS7
uniprot id: A0A6J3QQW8
uniprot id: A0A6J3QRB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTX family.
messages: Nucleus

9739:SEC31A
gene id: 9739:SEC31A
uniprot id: A0A2U4B581
uniprot id: A0A2U4B585
uniprot id: A0A2U4B595
uniprot id: A0A2U4B596
uniprot id: A0A2U4B599
uniprot id: A0A2U4B5B2
uniprot id: A0A2U4B5D4
uniprot id: A0A2U4B5E5
uniprot id: A0A2U4B5F0
uniprot id: A0A2U4B5M6
uniprot id: A0A2U4B5P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC31 family.
messages: Endoplasmic reticulum membrane

9739:CLIC1
gene id: 9739:CLIC1
uniprot id: A0A6J3RZL5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cell membrane
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane
messages: Nucleus membrane

9739:GPKOW
gene id: 9739:GPKOW
uniprot id: A0A6J3QRI6
uniprot id: A0A6J3QSD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MOS2 family.
messages: Nucleus
messages: RNA-binding protein involved in pre-mRNA splicing.

9739:MYO6
gene id: 9739:MYO6
uniprot id: A0A2U4AV93
uniprot id: A0A2U4AVB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: clathrin-coated pit
messages: clathrin-coated vesicle
messages: filopodium
messages: microvillus
messages: ruffle membrane
messages: trans-Golgi network membrane

9739:APOE
gene id: 9739:APOE
uniprot id: A0A6J3QDI6
uniprot id: A0A6J3QDS8
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

9739:UNC119B
gene id: 9739:UNC119B
uniprot id: A0A2U3V1L0
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

9739:RPN1
gene id: 9739:RPN1
uniprot id: A0A2U3V2W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

9739:CA10
gene id: 9739:CA10
uniprot id: A0A2U4C6J8
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Does not have a catalytic activity.

9739:SCRIB
gene id: 9739:SCRIB
uniprot id: A0A6J3Q8B4
uniprot id: A0A6J3Q8C1
uniprot id: A0A6J3Q8C2
uniprot id: A0A6J3Q8C6
uniprot id: A0A6J3Q8C7
uniprot id: A0A6J3Q8D1
uniprot id: A0A6J3Q8D2
uniprot id: A0A6J3Q8R6
uniprot id: A0A6J3Q8S2
uniprot id: A0A6J3Q937
uniprot id: A0A6J3Q942
uniprot id: A0A6J3Q943
uniprot id: A0A6J3Q946
uniprot id: A0A6J3Q953
names: Similarity
messages: Belongs to the LAP (LRR and PDZ) protein family.

9739:KIF7
gene id: 9739:KIF7
uniprot id: A0A6J3QZT6
uniprot id: A0A6J3R038
uniprot id: A0A6J3R0H5
uniprot id: A0A6J3R0I0
uniprot id: A0A6J3R0L5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9739:LOC101332599
gene id: 9739:LOC101332599
uniprot id: A0A2U4BM32
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

9739:FUS
gene id: 9739:FUS
uniprot id: A0A6J3Q4L8
uniprot id: A0A6J3Q520
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TET family.
messages: Nucleus

9739:TNS4
gene id: 9739:TNS4
uniprot id: A0A6J3QP49
uniprot id: A0A6J3QPQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTEN phosphatase protein family.
messages: focal adhesion

9739:CACNA1F
gene id: 9739:CACNA1F
uniprot id: A0A6J3QSA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death.

9739:FAM122A
gene id: 9739:FAM122A
uniprot id: A0A2U3V6N1
names: Similarity
messages: Belongs to the FAM122 family.

9739:SENP3
gene id: 9739:SENP3
uniprot id: A0A2U3VA87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C48 family.
messages: nucleolus

9739:LOC101321748
gene id: 9739:LOC101321748
uniprot id: A0A2U4BBU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9739:ABCC2
gene id: 9739:ABCC2
uniprot id: A0A6J3Q6C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

9739:LOC101334624
gene id: 9739:LOC101334624
uniprot id: A0A2U3V2Y0
uniprot id: A0A6J3QQV3
uniprot id: A0A6J3QR00
uniprot id: A0A6J3QRK7
uniprot id: A0A6J3QRL9
names: Similarity
messages: Belongs to the NHS family.

9739:NFYA
gene id: 9739:NFYA
uniprot id: A0A6J3RZY0
uniprot id: A0A6J3RZY4
uniprot id: A0A6J3RZY9
uniprot id: A0A6J3S052
uniprot id: A0A6J3S054
uniprot id: A0A6J3S0F2
uniprot id: A0A6J3S102
uniprot id: A0A6J3S107
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NFYA/HAP2 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
messages: Heterotrimer.
messages: Nucleus

9739:TNK1
gene id: 9739:TNK1
uniprot id: A0A6J3QJ06
uniprot id: A0A6J3QJ22
uniprot id: A0A6J3QJ25
uniprot id: A0A6J3QJL8
uniprot id: A0A6J3QJN5
uniprot id: A0A6J3QJP2
uniprot id: A0A6J3QK47
uniprot id: A0A6J3QK52
names: Subcellular Location Annotation
messages: Cell membrane

9739:NEU2
gene id: 9739:NEU2
uniprot id: A0A2U4ADX5
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

9739:DUSP6
gene id: 9739:DUSP6
uniprot id: A0A2U3UZS3
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

9739:KCNA5
gene id: 9739:KCNA5
uniprot id: A0A6J3S4N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.5/KCNA5 sub-subfamily.
messages: Cell membrane
messages: Membrane

9739:CIT
gene id: 9739:CIT
uniprot id: A0A6J3PRJ3
uniprot id: A0A6J3PRK1
uniprot id: A0A6J3PRP8
uniprot id: A0A6J3PS36
uniprot id: A0A6J3PS43
uniprot id: A0A6J3PS66
uniprot id: A0A6J3PSN0
uniprot id: A0A6J3PSN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cytoplasm
messages: Plays a role in cytokinesis. Displays serine/threonine protein kinase activity.

9739:NR0B1
gene id: 9739:NR0B1
uniprot id: A0A2U3V4W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus
messages: Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency.

9739:EFNB3
gene id: 9739:EFNB3
uniprot id: A0A6J3QPX7
uniprot id: A0A6J3QQH4
names: Caution
names: Similarity
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:RAD50
gene id: 9739:RAD50
uniprot id: A0A2U4AGN4
names: Similarity
messages: Belongs to the SMC family. RAD50 subfamily.

9739:DOK3
gene id: 9739:DOK3
uniprot id: A0A2U4BZ83
names: Similarity
messages: Belongs to the DOK family. Type A subfamily.

9739:ACTR5
gene id: 9739:ACTR5
uniprot id: A0A6J3Q4P0
names: Similarity
messages: Belongs to the actin family.

9739:LGR5
gene id: 9739:LGR5
uniprot id: A0A2U4CQD6
uniprot id: A0A2U4CQD8
uniprot id: A0A2U4CQP2
names: Subcellular Location Annotation
messages: Membrane

9739:KLC4
gene id: 9739:KLC4
uniprot id: A0A6J3S073
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

9739:LOC101337565
gene id: 9739:LOC101337565
uniprot id: A0A6J3QSI6
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

9739:RPS23
gene id: 9739:RPS23
uniprot id: A0A2U3V7F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Rough endoplasmic reticulum

9739:PSMA7
gene id: 9739:PSMA7
uniprot id: A0A2U3V0M9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

9739:PRICKLE3
gene id: 9739:PRICKLE3
uniprot id: A0A6J3QU25
uniprot id: A0A6J3QUI2
uniprot id: A0A6J3QVR0
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

9739:YIPF5
gene id: 9739:YIPF5
uniprot id: A0A2U4AGT1
uniprot id: A0A2U4AHA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

9739:EPN1
gene id: 9739:EPN1
uniprot id: A0A6J3QIN4
uniprot id: A0A6J3QIR6
uniprot id: A0A6J3QJ41
names: Similarity
messages: Belongs to the epsin family.

9739:LOC101332629
gene id: 9739:LOC101332629
uniprot id: A0A6J3Q8F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

9739:AKAP3
gene id: 9739:AKAP3
uniprot id: A0A2U4AL28
names: Similarity
messages: Belongs to the AKAP110 family.

9739:TRAM1L1
gene id: 9739:TRAM1L1
uniprot id: A0A2U3V8Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

9739:LOC101322615
gene id: 9739:LOC101322615
uniprot id: A0A6J3QQN3
names: Similarity
messages: Belongs to the intermediate filament family.

9739:RBM17
gene id: 9739:RBM17
uniprot id: A0A2U3V9D4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the spliceosome.
messages: Nucleus
messages: Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites.

9739:LMBR1
gene id: 9739:LMBR1
uniprot id: A0A2U4AXX5
uniprot id: A0A2U4AXX8
uniprot id: A0A2U4AXZ6
uniprot id: A0A2U4AXZ9
uniprot id: A0A2U4AYC6
uniprot id: A0A6J3RY41
uniprot id: A0A6J3RYU1
names: Similarity
messages: Belongs to the LIMR family.

9739:RENBP
gene id: 9739:RENBP
uniprot id: A0A6J3QR04
uniprot id: A0A6J3QR77
uniprot id: A0A6J3QRR8
uniprot id: A0A6J3QSB7
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

9739:SLC29A3
gene id: 9739:SLC29A3
uniprot id: A0A2U4BEQ5
uniprot id: A0A6J3Q688
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

9739:C13H12orf65
gene id: 9739:C13H12orf65
uniprot id: A0A2U4CKY0
uniprot id: A0A2U4CL61
uniprot id: A0A6J3PRS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

9739:LOC117309452
gene id: 9739:LOC117309452
uniprot id: A0A6J3QM05
names: Similarity
messages: Belongs to the intermediate filament family.

9739:SEPTIN12
gene id: 9739:SEPTIN12
uniprot id: A0A2U4ATN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cytoplasm
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

9739:NEFL
gene id: 9739:NEFL
uniprot id: A0A6J3RKD4
names: Similarity
messages: Belongs to the intermediate filament family.

9739:CBWD1
gene id: 9739:CBWD1
uniprot id: A0A2U3V2G4
uniprot id: A0A6J3RH72
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

9739:MYH15
gene id: 9739:MYH15
uniprot id: A0A6J3R922
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:KHDRBS3
gene id: 9739:KHDRBS3
uniprot id: A0A2U4B2S7
uniprot id: A0A2U4B2U9
uniprot id: A0A2U4B2V3
uniprot id: A0A2U4B2X6
names: Similarity
messages: Belongs to the KHDRBS family.

9739:B4GAT1
gene id: 9739:B4GAT1
uniprot id: A0A2U4BIZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 49 family.
messages: Golgi apparatus membrane
messages: Membrane

9739:DYNC1LI1
gene id: 9739:DYNC1LI1
uniprot id: A0A2U4CAJ3
uniprot id: A0A2U4CAL1
uniprot id: A0A2U4CAR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

9739:HSD17B13
gene id: 9739:HSD17B13
uniprot id: A0A2U4AMZ3
uniprot id: A0A2U4ANC7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9739:VAMP1
gene id: 9739:VAMP1
uniprot id: A0A6J3S7W9
uniprot id: A0A6J3S969
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

9739:GADD45GIP1
gene id: 9739:GADD45GIP1
uniprot id: A0A6J3R618
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.
messages: Belongs to the mitochondrion-specific ribosomal protein mL64 family.
messages: Mitochondrion
messages: Nucleus

9739:LOC117312604
gene id: 9739:LOC117312604
uniprot id: A0A6J3RHG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

9739:LOC117310062
gene id: 9739:LOC117310062
uniprot id: A0A6J3QRL3
names: Similarity
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.

9739:TMCC2
gene id: 9739:TMCC2
uniprot id: A0A6J3R136
uniprot id: A0A6J3R142
uniprot id: A0A6J3R152
uniprot id: A0A6J3R2X9
uniprot id: A0A6J3R2Y5
uniprot id: A0A6J3R2Z0
names: Similarity
messages: Belongs to the TEX28 family.

9739:MOXD1
gene id: 9739:MOXD1
uniprot id: A0A2U4CPQ9
names: Similarity
messages: Belongs to the copper type II ascorbate-dependent monooxygenase family.

9739:CELSR2
gene id: 9739:CELSR2
uniprot id: A0A6J3RUM3
uniprot id: A0A6J3RUM8
uniprot id: A0A6J3RUW6
uniprot id: A0A6J3RUY8
uniprot id: A0A6J3RV05
uniprot id: A0A6J3RVE8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor that may have an important role in cell/cell signaling during nervous system formation.

9739:ATP6V1E2
gene id: 9739:ATP6V1E2
uniprot id: A0A2U4BYJ2
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

9739:VAPB
gene id: 9739:VAPB
uniprot id: A0A2U3V448
uniprot id: A0A2U4C246
uniprot id: A0A2U4C284
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:LOC101319529
gene id: 9739:LOC101319529
uniprot id: A0A2U4B044
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

9739:LETMD1
gene id: 9739:LETMD1
uniprot id: A0A2U4CBF8
uniprot id: A0A2U4CBG0
uniprot id: A0A6J3S6Z6
uniprot id: A0A6J3S869
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

9739:CASKIN2
gene id: 9739:CASKIN2
uniprot id: A0A6J3QLP5
uniprot id: A0A6J3QM70
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

9739:HNRNPF
gene id: 9739:HNRNPF
uniprot id: A0A2U4BE07
names: Subcellular Location Annotation
messages: nucleoplasm

9739:LOC109547549
gene id: 9739:LOC109547549
uniprot id: A0A2U4A5T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:RBBP5
gene id: 9739:RBBP5
uniprot id: A0A2U3ZYJ8
uniprot id: A0A2U3ZYJ9
uniprot id: A0A2U3ZYL5
uniprot id: A0A2U3ZZJ8
names: Subcellular Location Annotation
messages: Nucleus

9739:EPC1
gene id: 9739:EPC1
uniprot id: A0A2U4B779
uniprot id: A0A2U4B7M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enhancer of polycomb family.
messages: Nucleus

9739:TTC21A
gene id: 9739:TTC21A
uniprot id: A0A6J3S1P9
names: Similarity
messages: Belongs to the TTC21 family.

9739:PPIE
gene id: 9739:PPIE
uniprot id: A0A6J3PTG7
uniprot id: A0A6J3PTI6
uniprot id: A0A6J3PTX7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.
messages: Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

9739:ANKS3
gene id: 9739:ANKS3
uniprot id: A0A2U4ATS0
uniprot id: A0A2U4ATU2
uniprot id: A0A6J3PYF6
uniprot id: A0A6J3PYH4
uniprot id: A0A6J3PYR4
uniprot id: A0A6J3PZ33
names: Function
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

9739:LOC101333580
gene id: 9739:LOC101333580
uniprot id: A0A6J3Q1S9
names: Subcellular Location Annotation
messages: Nucleus

9739:TMEM216
gene id: 9739:TMEM216
uniprot id: A0A2U3V430
uniprot id: A0A6J3RQP8
names: Subcellular Location Annotation
messages: Membrane

9739:APOC4
gene id: 9739:APOC4
uniprot id: A0A6J3QIE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apolipoprotein C4 family.
messages: May participate in lipoprotein metabolism.
messages: Secreted

9739:BMS1
gene id: 9739:BMS1
uniprot id: A0A2U4BE44
names: Subcellular Location Annotation
messages: nucleolus

9739:LOC101323978
gene id: 9739:LOC101323978
uniprot id: A0A6J3REL7
names: Similarity
messages: Belongs to the TRM112 family.

9739:LOC117312227
gene id: 9739:LOC117312227
uniprot id: A0A6J3QV83
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Component of the 43S pre-initiation complex (43S PIC), which binds to the mRNA cap-proximal region, scans mRNA 5'-untranslated region, and locates the initiation codon. This protein enhances formation of the cap-proximal complex. Together with EIF1, facilitates scanning, start codon recognition, promotion of the assembly of 48S complex at the initiation codon (43S PIC becomes 48S PIC after the start codon is reached), and dissociation of aberrant complexes. After start codon location, together with EIF5B orients the initiator methionine-tRNA in a conformation that allows 60S ribosomal subunit joining to form the 80S initiation complex. Is released after 80S initiation complex formation, just after GTP hydrolysis by EIF5B, and before release of EIF5B. Its globular part is located in the A site of the 40S ribosomal subunit. Its interaction with EIF5 during scanning contribute to the maintenance of EIF1 within the open 43S PIC. In contrast to yeast orthologs, does not bind EIF1.

9739:WEE2
gene id: 9739:WEE2
uniprot id: A0A2U4B873
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
messages: Binds 2 magnesium ions per subunit.
messages: Nucleus

9739:DBR1
gene id: 9739:DBR1
uniprot id: A0A2U3V6J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lariat debranching enzyme family.
messages: Nucleus

9739:SLC16A3
gene id: 9739:SLC16A3
uniprot id: A0A6J3QLI6
uniprot id: A0A6J3QM82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

9739:CD5L
gene id: 9739:CD5L
uniprot id: A0A6J3RQI9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:PATJ
gene id: 9739:PATJ
uniprot id: A0A2U4BXP0
uniprot id: A0A6J3S3K6
uniprot id: A0A6J3S3U7
uniprot id: A0A6J3S3W2
uniprot id: A0A6J3S4I8
names: Subcellular Location Annotation
messages: Cell membrane
messages: tight junction

9739:LOC101334551
gene id: 9739:LOC101334551
uniprot id: A0A2U4BF30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB7 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

9739:CD79B
gene id: 9739:CD79B
uniprot id: A0A6J3QK60
uniprot id: A0A6J3QKN2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9739:LOC117312553
gene id: 9739:LOC117312553
uniprot id: A0A6J3RHR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

9739:SAMD8
gene id: 9739:SAMD8
uniprot id: A0A2U4BEB7
uniprot id: A0A2U4BEC0
uniprot id: A0A2U4BEC2
uniprot id: A0A2U4BEF1
uniprot id: A0A6J3Q7F1
uniprot id: A0A6J3Q874
uniprot id: A0A6J3Q893
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

9739:LOC101316502
gene id: 9739:LOC101316502
uniprot id: A0A2U4AAR2
uniprot id: A0A2U4ABC1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:MZT2B
gene id: 9739:MZT2B
uniprot id: A0A2U4ALR2
uniprot id: A0A6J3PSY5
uniprot id: A0A6J3PT45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MOZART2 family.
messages: centrosome
messages: spindle

9739:GOLGA5
gene id: 9739:GOLGA5
uniprot id: A0A2U3ZZZ1
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport.

9739:TECR
gene id: 9739:TECR
uniprot id: A0A6J3R6M2
uniprot id: A0A6J3R8C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:SPAM1
gene id: 9739:SPAM1
uniprot id: A0A2U3UYU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 56 family.
messages: Cell membrane
messages: Membrane

9739:TUBGCP5
gene id: 9739:TUBGCP5
uniprot id: A0A2U4B2A1
uniprot id: A0A2U4B2B4
uniprot id: A0A2U4B2P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome
messages: microtubule organizing center

9739:AWAT2
gene id: 9739:AWAT2
uniprot id: A0A2U4CGC8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:MED4
gene id: 9739:MED4
uniprot id: A0A2U4BFZ5
uniprot id: A0A2U4BG33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 4 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

9739:GPR146
gene id: 9739:GPR146
uniprot id: A0A2U4BRY7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9739:LOC101318802
gene id: 9739:LOC101318802
uniprot id: A0A2U4ARU1
uniprot id: A0A2U4AS95
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

9739:SEPSECS
gene id: 9739:SEPSECS
uniprot id: A0A2U4ASM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepSecS family.
messages: Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm
messages: Homotetramer formed by a catalytic dimer and a non-catalytic dimer serving as a binding platform that orients tRNASec for catalysis. Each tetramer binds the CCA ends of two tRNAs which point to the active sites of the catalytic dimer.

9739:HSPB2
gene id: 9739:HSPB2
uniprot id: A0A6J3RSA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: Nucleus

9739:LOC117313568
gene id: 9739:LOC117313568
uniprot id: A0A6J3RXK0
names: Similarity
messages: Belongs to the IFRD family.

9739:LOC101332475
gene id: 9739:LOC101332475
uniprot id: A0A6J3PSS9
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

9739:IRF7
gene id: 9739:IRF7
uniprot id: A0A6J3RS72
uniprot id: A0A6J3RSV5
names: Subcellular Location Annotation
messages: Nucleus

9739:IFNGR2
gene id: 9739:IFNGR2
uniprot id: A0A2U4ACA3
names: Subcellular Location Annotation
messages: Membrane

9739:ANXA10
gene id: 9739:ANXA10
uniprot id: A0A2U4B3S3
names: Similarity
messages: Belongs to the annexin family.

9739:HTR4
gene id: 9739:HTR4
uniprot id: A0A2U4AHK0
uniprot id: A0A2U4AHT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Endosome
messages: Membrane
messages: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.

9739:CDKN1B
gene id: 9739:CDKN1B
uniprot id: A0A6J3S8C9
names: Similarity
messages: Belongs to the CDI family.

9739:TIMM50
gene id: 9739:TIMM50
uniprot id: A0A6J3QFX9
uniprot id: A0A6J3QGJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM50 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Mitochondrion inner membrane

9739:PRR15
gene id: 9739:PRR15
uniprot id: A0A2U4B121
names: Similarity
messages: Belongs to the PRR15 family.

9739:LOC101324838
gene id: 9739:LOC101324838
uniprot id: A0A2U4AZF6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9739:LOC101335403
gene id: 9739:LOC101335403
uniprot id: A0A2U3V695
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIII family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

9739:LOC101334420
gene id: 9739:LOC101334420
uniprot id: A0A2U4CMB7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

9739:LOC101328860
gene id: 9739:LOC101328860
uniprot id: A0A2U3V349
uniprot id: A0A2U4CIL9
names: Similarity
messages: Belongs to the MHC class II family.

9739:DNAJC24
gene id: 9739:DNAJC24
uniprot id: A0A2U4CDQ1
uniprot id: A0A6J3RVH4
names: Similarity
messages: Belongs to the DPH4 family.

9739:CFL1
gene id: 9739:CFL1
uniprot id: A0A6J3RR28
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

9739:CRYAB
gene id: 9739:CRYAB
uniprot id: A0A2U3V740
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.
messages: Nucleus

9739:ST3GAL1
gene id: 9739:ST3GAL1
uniprot id: A0A6J3Q807
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9739:RRM1
gene id: 9739:RRM1
uniprot id: A0A2U4BPQ1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

9739:FERMT2
gene id: 9739:FERMT2
uniprot id: A0A2U4AEL3
names: Similarity
messages: Belongs to the kindlin family.

9739:FES
gene id: 9739:FES
uniprot id: A0A6J3R0M2
uniprot id: A0A6J3R1Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.
messages: Cell membrane
messages: Membrane
messages: cytoskeleton

9739:LOC101321498
gene id: 9739:LOC101321498
uniprot id: A0A2U3V1Q5
names: Function
names: Similarity
messages: Belongs to the PET191 family.
messages: Involved in an early step of the mitochondrial complex IV assembly process.

9739:TEX28
gene id: 9739:TEX28
uniprot id: A0A2U4B7J1
names: Similarity
messages: Belongs to the TEX28 family.

9739:RBM42
gene id: 9739:RBM42
uniprot id: A0A2U4BUA0
uniprot id: A0A2U4BUA2
uniprot id: A0A2U4BUF9
names: Similarity
messages: Belongs to the RRM RBM42 family.

9739:PARP3
gene id: 9739:PARP3
uniprot id: A0A6J3S379
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Nucleus

9739:SCARF1
gene id: 9739:SCARF1
uniprot id: A0A6J3QQT1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:LPIN2
gene id: 9739:LPIN2
uniprot id: A0A2U4A5R9
uniprot id: A0A2U4A5S0
uniprot id: A0A2U4A6L1
names: Similarity
messages: Belongs to the lipin family.

9739:LONP1
gene id: 9739:LONP1
uniprot id: A0A6J3R6Q9
uniprot id: A0A6J3R7N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand-specific manner. May regulate mitochondrial DNA replication and/or gene expression using site-specific, single-stranded DNA binding to target the degradation of regulatory proteins binding to adjacent sites in mitochondrial promoters.
messages: Belongs to the peptidase S16 family.
messages: Homohexamer. Organized in a ring with a central cavity. The ATP-binding and proteolytic domains (AP-domain) form a hexameric chamber, while the N-terminal domain is arranged as a trimer of dimers. DNA and RNA binding is stimulated by substrate and inhibited by ATP binding. Interacts with TWNK and mitochondrial DNA polymerase subunit POLG.
messages: Mitochondrion matrix

9739:BASP1
gene id: 9739:BASP1
uniprot id: A0A6J3R1V4
names: Similarity
messages: Belongs to the BASP1 family.

9739:ABRAXAS2
gene id: 9739:ABRAXAS2
uniprot id: A0A2U3V1G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM175 family. Abro1 subfamily.
messages: Nucleus
messages: spindle pole

9739:FAM193A
gene id: 9739:FAM193A
uniprot id: A0A6J3RC96
uniprot id: A0A6J3RCE4
uniprot id: A0A6J3RCE6
uniprot id: A0A6J3RCY8
uniprot id: A0A6J3RD66
uniprot id: A0A6J3RD69
uniprot id: A0A6J3RER3
uniprot id: A0A6J3RER6
names: Similarity
messages: Belongs to the FAM193 family.

9739:KIF27
gene id: 9739:KIF27
uniprot id: A0A2U4BRS0
uniprot id: A0A2U4BRS5
uniprot id: A0A2U4BRT1
uniprot id: A0A2U4BRT5
uniprot id: A0A2U4BRT6
uniprot id: A0A2U4BRU0
uniprot id: A0A2U4BRU6
uniprot id: A0A2U4BRY6
uniprot id: A0A2U4BRZ1
uniprot id: A0A2U4BS34
uniprot id: A0A2U4BS39
uniprot id: A0A6J3RG87
uniprot id: A0A6J3RGF8
uniprot id: A0A6J3RIG5
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:GTF2F1
gene id: 9739:GTF2F1
uniprot id: A0A6J3R6L7
uniprot id: A0A6J3R6R2
uniprot id: A0A6J3R762
uniprot id: A0A6J3R7K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF alpha subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.

9739:TMPRSS11A
gene id: 9739:TMPRSS11A
uniprot id: A0A2U4ARQ8
uniprot id: A0A2U4ARR3
uniprot id: A0A2U4ARS2
uniprot id: A0A2U4AS73
uniprot id: A0A6J3RDZ2
uniprot id: A0A6J3RE13
uniprot id: A0A6J3REJ9
uniprot id: A0A6J3RG99
uniprot id: A0A6J3RGA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Membrane

9739:ELAVL3
gene id: 9739:ELAVL3
uniprot id: A0A6J3R981
names: Similarity
messages: Belongs to the RRM elav family.

9739:ARRDC5
gene id: 9739:ARRDC5
uniprot id: A0A6J3R8H0
names: Similarity
messages: Belongs to the arrestin family.

9739:ACOT8
gene id: 9739:ACOT8
uniprot id: A0A2U3V3V1
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

9739:STK32B
gene id: 9739:STK32B
uniprot id: A0A2U4ARM4
uniprot id: A0A2U4ARN1
names: Similarity
messages: Belongs to the protein kinase superfamily.

9739:HAGH
gene id: 9739:HAGH
uniprot id: A0A2U4BMT6
uniprot id: A0A6J3Q3U3
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

9739:KATNA1
gene id: 9739:KATNA1
uniprot id: A0A2U4CPY6
names: Activity Regulation
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.
messages: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit. Interacts with ASPM; the katanin complex formation KATNA1:KATNB1 is required for the association of ASPM. Interacts with dynein and NDEL1. Associates with the E3 ligase complex containing DYRK2, EDD/UBR5, DDB1 and DCAF1 proteins (EDVP complex). Interacts with KLHL42 (via the kelch domains). Interacts with CUL3; the interaction is enhanced by KLHL42. Interacts with KATNB1 and KATNBL1. Interacts with CAMSAP2 and CAMSAP3; leading to regulate the length of CAMSAP-decorated microtubule stretches.
messages: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.
messages: Cytoplasm
messages: Midbody
messages: Phosphorylation by DYRK2 triggers ubiquitination and subsequent degradation.
messages: The N-terminus is sufficient for interaction with microtubules, although high affinity binding to microtubules also requires an intact C-terminal domain and ATP, which promotes oligomerization.
messages: Ubiquitinated by the BCR(KLHL42) E3 ubiquitin ligase complex, leading to its proteasomal degradation. Ubiquitinated by the EDVP E3 ligase complex and subsequently targeted for proteasomal degradation.
messages: centrosome
messages: spindle
messages: spindle pole

9739:SOD3
gene id: 9739:SOD3
uniprot id: A0A2U4ASL8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

9739:FAM229A
gene id: 9739:FAM229A
uniprot id: A0A2U4BKN0
names: Similarity
messages: Belongs to the FAM229 family.

9739:SVOPL
gene id: 9739:SVOPL
uniprot id: A0A6J3RVJ3
names: Subcellular Location Annotation
messages: Membrane

9739:AATF
gene id: 9739:AATF
uniprot id: A0A2U3UYH5
uniprot id: A0A6J3QNT4
uniprot id: A0A6J3QPM3
uniprot id: A0A6J3QQ01
names: Similarity
messages: Belongs to the AATF family.

9739:LOC101331937
gene id: 9739:LOC101331937
uniprot id: A0A2U3V4F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

9739:PPP4R2
gene id: 9739:PPP4R2
uniprot id: A0A2U4CCN6
uniprot id: A0A6J3S2T3
uniprot id: A0A6J3S2W9
uniprot id: A0A6J3S3H9
uniprot id: A0A6J3S3U1
names: Similarity
messages: Belongs to the PPP4R2 family.

9739:DOCK9
gene id: 9739:DOCK9
uniprot id: A0A2U4A5X5
uniprot id: A0A2U4A5X7
uniprot id: A0A2U4A5Y1
uniprot id: A0A2U4A5Y2
uniprot id: A0A2U4A5Y4
uniprot id: A0A2U4A5Y6
uniprot id: A0A2U4A5Y7
uniprot id: A0A2U4A5Y8
uniprot id: A0A2U4A5Z1
uniprot id: A0A2U4A5Z3
uniprot id: A0A2U4A5Z8
uniprot id: A0A2U4A622
uniprot id: A0A2U4A627
uniprot id: A0A2U4A632
uniprot id: A0A2U4A638
uniprot id: A0A2U4A6S0
uniprot id: A0A2U4A6S6
uniprot id: A0A2U4A6T1
uniprot id: A0A2U4A6T6
uniprot id: A0A6J3QAL1
uniprot id: A0A6J3QAL8
uniprot id: A0A6J3QAZ6
uniprot id: A0A6J3QB01
uniprot id: A0A6J3QB86
uniprot id: A0A6J3QBD1
names: Similarity
messages: Belongs to the DOCK family.

9739:LOC117310413
gene id: 9739:LOC117310413
uniprot id: A0A6J3QUL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

9739:NDRG3
gene id: 9739:NDRG3
uniprot id: A0A2U4CLL1
uniprot id: A0A2U4CLL2
uniprot id: A0A2U4CLL8
uniprot id: A0A6J3Q3T5
names: Similarity
messages: Belongs to the NDRG family.

9739:LOC117311030
gene id: 9739:LOC117311030
uniprot id: A0A6J3QWA6
uniprot id: A0A6J3QWH9
uniprot id: A0A6J3QWS2
uniprot id: A0A6J3QX65
uniprot id: A0A6J3QY54
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

9739:LOC101327661
gene id: 9739:LOC101327661
uniprot id: A0A6J3QT71
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

9739:SMARCA5
gene id: 9739:SMARCA5
uniprot id: A0A2U4AM91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

9739:CWF19L2
gene id: 9739:CWF19L2
uniprot id: A0A2U4CFT3
uniprot id: A0A2U4CFT6
uniprot id: A0A2U4CFY0
names: Similarity
messages: Belongs to the CWF19 family.

9739:LOC101318554
gene id: 9739:LOC101318554
uniprot id: A0A2U3V8C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGR2 family.
messages: Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.
messages: Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation.
messages: Mitochondrion inner membrane

9739:BARX2
gene id: 9739:BARX2
uniprot id: A0A2U4BWV7
names: Subcellular Location Annotation
messages: Nucleus

9739:GPR52
gene id: 9739:GPR52
uniprot id: A0A2U3V895
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9739:TIMM9
gene id: 9739:TIMM9
uniprot id: A0A2U4ADA9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

9739:DDX3X
gene id: 9739:DDX3X
uniprot id: A0A6J3QTV4
uniprot id: A0A6J3QUC1
uniprot id: A0A6J3QUI9
uniprot id: A0A6J3QUS9
names: Similarity
messages: Belongs to the DEAD box helicase family.

9739:PARP1
gene id: 9739:PARP1
uniprot id: A0A6J3QZM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARTD/PARP family.
messages: Chromosome
messages: Interacts (when auto-poly-ADP-ribosylated) with AIFM1.
messages: Nucleus
messages: Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair.
messages: This cleavage form irreversibly binds to DNA breaks and interferes with DNA repair, promoting DNA damage-induced apoptosis.

9739:LOC101327843
gene id: 9739:LOC101327843
uniprot id: A0A6J3RSK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

9739:NAGPA
gene id: 9739:NAGPA
uniprot id: A0A6J3Q0H0
uniprot id: A0A6J3Q0I8
uniprot id: A0A6J3Q0Q8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:CPXM1
gene id: 9739:CPXM1
uniprot id: A0A2U4CM08
uniprot id: A0A2U4CM11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

9739:A4GALT
gene id: 9739:A4GALT
uniprot id: A0A6J3S5P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 32 family.
messages: Golgi apparatus membrane

9739:SLC13A2
gene id: 9739:SLC13A2
uniprot id: A0A6J3QN27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

9739:SUGP1
gene id: 9739:SUGP1
uniprot id: A0A6J3R581
uniprot id: A0A6J3R5B1
uniprot id: A0A6J3R5U0
names: Subcellular Location Annotation
messages: Nucleus

9739:OTOP2
gene id: 9739:OTOP2
uniprot id: A0A6J3QLG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

9739:LOC101327249
gene id: 9739:LOC101327249
uniprot id: A0A2U4CD74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I NDUFA13 subunit family.
messages: Complex I functions in the transfer of electrons from NADH to the respiratory chain. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.
messages: Mitochondrion inner membrane

9739:SLC25A13
gene id: 9739:SLC25A13
uniprot id: A0A2U4AQJ5
uniprot id: A0A2U4AQK1
uniprot id: A0A2U4AR02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

9739:EXOC5
gene id: 9739:EXOC5
uniprot id: A0A2U4ADS1
uniprot id: A0A2U4AEA7
names: Similarity
messages: Belongs to the SEC10 family.

9739:PDIA6
gene id: 9739:PDIA6
uniprot id: A0A2U3UYG1
uniprot id: A0A6J3PVN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen
messages: Melanosome

9739:ING1
gene id: 9739:ING1
uniprot id: A0A2U4A664
uniprot id: A0A2U4A6B4
uniprot id: A0A2U4A706
uniprot id: A0A6J3QAH5
uniprot id: A0A6J3QBB5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

9739:GAL
gene id: 9739:GAL
uniprot id: A0A6J3RRA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galanin family.
messages: Secreted

9739:PATL1
gene id: 9739:PATL1
uniprot id: A0A2U4CEI9
names: Similarity
messages: Belongs to the PAT1 family.

9739:ABITRAM
gene id: 9739:ABITRAM
uniprot id: A0A2U4C8Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABITRAM family.
messages: growth cone
messages: lamellipodium

9739:RPS16
gene id: 9739:RPS16
uniprot id: A0A2U3V484
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

9739:MSRB1
gene id: 9739:MSRB1
uniprot id: A0A6J3PZH7
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.

9739:OTP
gene id: 9739:OTP
uniprot id: A0A2U3V9P2
names: Subcellular Location Annotation
messages: Nucleus

9739:TNFRSF6B
gene id: 9739:TNFRSF6B
uniprot id: A0A2U4CN01
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:KHDRBS1
gene id: 9739:KHDRBS1
uniprot id: A0A2U3V478
names: Similarity
messages: Belongs to the KHDRBS family.

9739:ZPBP2
gene id: 9739:ZPBP2
uniprot id: A0A2U3UZ55
uniprot id: A0A2U3UZ57
uniprot id: A0A2U3UZI2
uniprot id: A0A6J3QLX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the zona pellucida-binding protein Sp38 family.
messages: Secreted
messages: acrosome

9739:GAREM2
gene id: 9739:GAREM2
uniprot id: A0A6J3PXT5
uniprot id: A0A6J3PY43
names: Similarity
messages: Belongs to the GAREM family.

9739:AGXT2
gene id: 9739:AGXT2
uniprot id: A0A2U4AXN1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

9739:ZDHHC21
gene id: 9739:ZDHHC21
uniprot id: A0A2U4BB17
uniprot id: A0A2U4BB21
uniprot id: A0A6J3RH88
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9739:SNRPA
gene id: 9739:SNRPA
uniprot id: A0A6J3QD80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM U1 A/B'' family.
messages: Nucleus

9739:SPON2
gene id: 9739:SPON2
uniprot id: A0A6J3RCZ5
names: Subcellular Location Annotation
messages: extracellular matrix

9739:LHX2
gene id: 9739:LHX2
uniprot id: A0A6J3RI90
names: Subcellular Location Annotation
messages: Nucleus

9739:KRT18
gene id: 9739:KRT18
uniprot id: A0A6J3S6J0
names: Similarity
messages: Belongs to the intermediate filament family.

9739:VPS33A
gene id: 9739:VPS33A
uniprot id: A0A2U4CKX0
uniprot id: A0A6J3PRA7
uniprot id: A0A6J3PRG2
uniprot id: A0A6J3PRU4
uniprot id: A0A6J3PSD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: clathrin-coated vesicle

9739:TBX21
gene id: 9739:TBX21
uniprot id: A0A6J3QNK3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9739:IL1A
gene id: 9739:IL1A
uniprot id: A0A2U4B015
uniprot id: Q9TTK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-1 family.
messages: Cytokine constitutively present intracellularly in nearly all resting non-hematopoietic cells that plays an important role in inflammation and bridges the innate and adaptive immune systems. After binding to its receptor IL1R1 together with its accessory protein IL1RAP, forms the high affinity interleukin-1 receptor complex. Signaling involves the recruitment of adapter molecules such as MYD88, IRAK1 or IRAK4. In turn, mediates the activation of NF-kappa-B and the three MAPK pathways p38, p42/p44 and JNK pathways. Within the cell, acts as an alarmin and cell death results in its liberation in the extracellular space after disruption of the cell membrane to induce inflammation and alert the host to injury or damage. In addition to its role as a danger signal, which occurs when the cytokine is passively released by cell necrosis, directly senses DNA damage and acts as signal for genotoxic stress without loss of cell integrity.
messages: Cytoplasm
messages: Monomer. Interacts with TMED10; the interaction mediates the translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) and thereby secretion. Interacts with IL1R1. Interacts with S100A13; this interaction is the first step in the export of IL1A, followed by direct translocation of this complex across the plasma membrane.
messages: Secreted

9739:STAC
gene id: 9739:STAC
uniprot id: A0A2U3V5Y0
uniprot id: A0A6J3S0M3
uniprot id: A0A6J3S0T5
names: Subcellular Location Annotation
messages: sarcolemma

9739:COPG1
gene id: 9739:COPG1
uniprot id: A0A6J3S3C4
uniprot id: A0A6J3S3H7
uniprot id: A0A6J3S4A0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

9739:KATNB1
gene id: 9739:KATNB1
uniprot id: A0A6J3QFG3
uniprot id: A0A6J3QFH0
uniprot id: A0A6J3QG32
uniprot id: A0A6J3QGL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat KATNB1 family.
messages: Cytoplasm
messages: Interacts with KATNA1. This interaction enhances the microtubule binding and severing activity of KATNA1 and also targets this activity to the centrosome. This interaction is weakly competed by KATNBL1 which has a lower affinity for it. Interacts with ASPM; the katanin complex formation KATNA1:KATNB1 is required for the association of ASPM. Interacts with dynein, microtubules, NDEL1 and PAFAH1B1. Interacts with KATNAL1; this interaction is weakly competed by KATNBL1 which has a lower affinity for it. Interacts with CAMSAP2 and CAMSAP3; leading to regulate the length of CAMSAP-decorated microtubule stretches.
messages: Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.
messages: centrosome
messages: cytoskeleton
messages: spindle
messages: spindle pole

9739:TRPC7
gene id: 9739:TRPC7
uniprot id: A0A6J3R7Z1
names: Subcellular Location Annotation
messages: Membrane

9739:LOC117313777
gene id: 9739:LOC117313777
uniprot id: A0A6J3RYK5
names: Similarity
messages: Belongs to the serpin family.

9739:ACSL6
gene id: 9739:ACSL6
uniprot id: A0A6J3R2U4
uniprot id: A0A6J3R394
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.
messages: Endoplasmic reticulum membrane
messages: Mitochondrion outer membrane

9739:PPP1R1C
gene id: 9739:PPP1R1C
uniprot id: A0A2U4B1F4
uniprot id: A0A2U4B1U5
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 1 family.

9739:LOC101330510
gene id: 9739:LOC101330510
uniprot id: A0A2U3V312
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9739:KCNC1
gene id: 9739:KCNC1
uniprot id: A0A2U4CD76
names: Subcellular Location Annotation
messages: Membrane

9739:SDHAF3
gene id: 9739:SDHAF3
uniprot id: A0A2U4AQR8
uniprot id: A0A2U4AQT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I LYR family. SDHAF3 subfamily.
messages: Interacts with the iron-sulfur protein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.

9739:CARMIL3
gene id: 9739:CARMIL3
uniprot id: A0A6J3QYD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CARMIL family.
messages: Cytoplasm

9739:CDNF
gene id: 9739:CDNF
uniprot id: A0A2U3V290
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARMET family.
messages: Secreted

9739:FGF16
gene id: 9739:FGF16
uniprot id: A0A2U4B3E2
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9739:CFLAR
gene id: 9739:CFLAR
uniprot id: A0A2U4BNB2
uniprot id: A0A2U4BNB4
uniprot id: A0A2U4BNB8
names: Similarity
messages: Belongs to the peptidase C14A family.

9739:LOC101336980
gene id: 9739:LOC101336980
uniprot id: A0A6J3PYW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

9739:CITED2
gene id: 9739:CITED2
uniprot id: A0A2U3V0E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

9739:AACS
gene id: 9739:AACS
uniprot id: A0A6J3PR08
uniprot id: A0A6J3PR66
uniprot id: A0A6J3PRK0
uniprot id: A0A6J3PRP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Converts acetoacetate to acetoacetyl-CoA in the cytosol.
messages: cytosol

9739:FAM13B
gene id: 9739:FAM13B
uniprot id: A0A2U4AGD8
uniprot id: A0A2U4AGK1
uniprot id: A0A6J3R2W4
uniprot id: A0A6J3R2W8
uniprot id: A0A6J3R300
uniprot id: A0A6J3R305
uniprot id: A0A6J3R3F8
uniprot id: A0A6J3R3G1
uniprot id: A0A6J3R3R1
uniprot id: A0A6J3R3R6
uniprot id: A0A6J3R542
uniprot id: A0A6J3R547
names: Similarity
messages: Belongs to the FAM13 family.

9739:LOC117310431
gene id: 9739:LOC117310431
uniprot id: A0A6J3QUG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP25 family.
messages: nucleolus

9739:LOC101334183
gene id: 9739:LOC101334183
uniprot id: A0A6J3RLQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

9739:STT3A
gene id: 9739:STT3A
uniprot id: A0A2U4BVK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

9739:RDH5
gene id: 9739:RDH5
uniprot id: A0A6J3S672
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9739:LOC101323277
gene id: 9739:LOC101323277
uniprot id: A0A6J3Q567
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

9739:TM2D3
gene id: 9739:TM2D3
uniprot id: A0A2U3V5V0
uniprot id: A0A2U4C7T6
names: Subcellular Location Annotation
messages: Membrane

9739:CTNNB1
gene id: 9739:CTNNB1
uniprot id: A0A2U4CAG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: adherens junction

9739:TAF5
gene id: 9739:TAF5
uniprot id: A0A2U3V605
uniprot id: A0A2U3V6D9
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

9739:SLC30A6
gene id: 9739:SLC30A6
uniprot id: A0A2U3V8T6
uniprot id: A0A2U4BZE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

9739:CPNE6
gene id: 9739:CPNE6
uniprot id: A0A6J3QZ95
names: Similarity
messages: Belongs to the copine family.

9739:LOC117311658
gene id: 9739:LOC117311658
uniprot id: A0A6J3RE60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.
messages: Catalyzes viral DNA integration into the host chromosome, by performing a series of DNA cutting and joining reactions. This enzyme activity takes place after virion entry into a cell and reverse transcription of the RNA genome in dsDNA. The first step in the integration process is 3' processing. This step requires a complex comprising the viral genome, matrix protein and integrase. This complex is called the pre-integration complex (PIC). The integrase protein removes 2 nucleotides from each 3' end of the viral DNA, leaving recessed CA OH's at the 3' ends. In the second step that requires cell division, the PIC enters cell nucleus. In the third step, termed strand transfer, the integrase protein joins the previously processed 3' ends to the 5' ends of strands of target cellular DNA at the site of integration. The last step is viral DNA integration into host chromosome.
messages: Forms the spherical core of the virion that encapsulates the genomic RNA-nucleocapsid complex.
messages: Virion

9739:LOC117310383
gene id: 9739:LOC117310383
uniprot id: A0A6J3QV71
names: Subcellular Location Annotation
messages: Membrane

9739:ERRFI1
gene id: 9739:ERRFI1
uniprot id: A0A2U4AZU3
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus

9739:SLCO3A1
gene id: 9739:SLCO3A1
uniprot id: A0A2U4C7C8
uniprot id: A0A2U4C7E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

9739:AGPAT3
gene id: 9739:AGPAT3
uniprot id: A0A6J3RB50
uniprot id: A0A6J3RBV6
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

9739:LOC117313169
gene id: 9739:LOC117313169
uniprot id: A0A6J3RQ27
names: Similarity
messages: Belongs to the peptidase A1 family.

9739:ENKUR
gene id: 9739:ENKUR
uniprot id: A0A2U4B6Z4
uniprot id: A0A2U4B6Z6
names: Subcellular Location Annotation
messages: cilium axoneme

9739:TRIT1
gene id: 9739:TRIT1
uniprot id: A0A2U3V5N1
uniprot id: A0A2U4BKK2
names: Function
names: Similarity
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37.

9739:ATP11B
gene id: 9739:ATP11B
uniprot id: A0A2U4C860
uniprot id: A0A2U4C867
uniprot id: A0A2U4C869
uniprot id: A0A2U4C870
uniprot id: A0A2U4C8F3
uniprot id: A0A6J3R9X8
uniprot id: A0A6J3RAC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

9739:MYH8
gene id: 9739:MYH8
uniprot id: A0A2U4C347
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: myofibril

9739:SPATA6
gene id: 9739:SPATA6
uniprot id: A0A2U4BJK0
uniprot id: A0A2U4BJK3
names: Similarity
messages: Belongs to the SPATA6 family.

9739:ZNF408
gene id: 9739:ZNF408
uniprot id: A0A2U4CEC2
uniprot id: A0A2U4CED1
names: Subcellular Location Annotation
messages: Nucleus

9739:GIMAP6
gene id: 9739:GIMAP6
uniprot id: A0A6J3RXU8
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

9739:USP15
gene id: 9739:USP15
uniprot id: A0A2U4CRZ2
uniprot id: A0A2U4CS17
uniprot id: A0A2U4CS28
uniprot id: A0A2U4CS92
uniprot id: A0A6J3S5H6
uniprot id: A0A6J3S5P9
uniprot id: A0A6J3S735
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: Nucleus

9739:MRPS16
gene id: 9739:MRPS16
uniprot id: A0A2U3UZ81
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

9739:TMEM106C
gene id: 9739:TMEM106C
uniprot id: A0A2U4BA68
uniprot id: A0A2U4BAA3
names: Similarity
messages: Belongs to the TMEM106 family.

9739:CYRIB
gene id: 9739:CYRIB
uniprot id: A0A2U3V2H5
uniprot id: A0A2U3V2U7
uniprot id: A0A2U4B306
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CYRI family.
messages: Interacts with RAC1 (GTP-bound form preferentially).
messages: Membrane

9739:PTPRK
gene id: 9739:PTPRK
uniprot id: A0A6J3S9E7
uniprot id: A0A6J3SAN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Membrane

9739:CHST1
gene id: 9739:CHST1
uniprot id: A0A6J3RPY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

9739:S100A4
gene id: 9739:S100A4
uniprot id: A0A6J3RL12
names: Similarity
messages: Belongs to the S-100 family.

9739:LOC117309458
gene id: 9739:LOC117309458
uniprot id: A0A6J3QLM6
names: Subcellular Location Annotation
messages: Membrane

9739:MRPS18A
gene id: 9739:MRPS18A
uniprot id: A0A2U3V1E8
uniprot id: A0A2U4CJD6
names: Subcellular Location Annotation
messages: Mitochondrion

9739:NDST2
gene id: 9739:NDST2
uniprot id: A0A2U4BES0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

9739:GBA2
gene id: 9739:GBA2
uniprot id: A0A6J3RHQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the non-lysosomal glucosylceramidase family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.

9739:FXYD5
gene id: 9739:FXYD5
uniprot id: A0A6J3QES3
uniprot id: A0A6J3QFB0
uniprot id: A0A6J3QFB7
uniprot id: A0A6J3QFD0
uniprot id: A0A6J3QFT8
names: Similarity
messages: Belongs to the FXYD family.

9739:SVOP
gene id: 9739:SVOP
uniprot id: A0A2U4CKZ7
uniprot id: A0A6J3PS74
uniprot id: A0A6J3PSN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

9739:DRD2
gene id: 9739:DRD2
uniprot id: A0A2U3V4S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Membrane

9739:MND1
gene id: 9739:MND1
uniprot id: A0A2U4AMM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MND1 family.
messages: Nucleus
messages: Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis.

9739:RTCB
gene id: 9739:RTCB
uniprot id: A0A2U3V3U1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Catalytic component of the tRNA-splicing ligase complex.
messages: Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
messages: Cytoplasm
messages: Ligation probably proceeds through 3 nucleotidyl transfer steps, with 2',3'-cyclic phosphate termini being hydrolyzed to 3'-P termini in a step that precedes 3'-P activation with GMP. In the first nucleotidyl transfer step, RTCB reacts with GTP to form a covalent RTCB-histidine-GMP intermediate with release of PPi; in the second step, the GMP moiety is transferred to the RNA 3'-P; in the third step, the 5'-OH from the opposite RNA strand attacks the activated 3'-P to form a 3',5'-phosphodiester bond and release GMP.

9739:VPS54
gene id: 9739:VPS54
uniprot id: A0A2U4BYD9
uniprot id: A0A2U4BYE6
uniprot id: A0A2U4BYI2
uniprot id: A0A2U4BYJ4
uniprot id: A0A6J3PW89
uniprot id: A0A6J3PW96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS54 family.
messages: trans-Golgi network

9739:PER2
gene id: 9739:PER2
uniprot id: A0A2U4ADY6
uniprot id: A0A6J3RMG7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9739:CDC42BPB
gene id: 9739:CDC42BPB
uniprot id: A0A2U4CPZ8
uniprot id: A0A6J3QVD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
messages: Cytoplasm
messages: lamellipodium

9739:CDR2
gene id: 9739:CDR2
uniprot id: A0A6J3Q0K5
uniprot id: A0A6J3Q0T1
names: Similarity
messages: Belongs to the CDR2 family.

9739:S1PR5
gene id: 9739:S1PR5
uniprot id: A0A2U4B5Y0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9739:CDC14B
gene id: 9739:CDC14B
uniprot id: A0A2U4BRY5
uniprot id: A0A2U4BRZ4
uniprot id: A0A2U4BS02
uniprot id: A0A2U4BS99
uniprot id: A0A2U4BSA4
uniprot id: A0A6J3RG26
uniprot id: A0A6J3RG92
uniprot id: A0A6J3RIA8
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

9739:KAT2B
gene id: 9739:KAT2B
uniprot id: A0A2U4B9Y2
uniprot id: A0A6J3R8I1
uniprot id: A0A6J3R8Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. GCN5 subfamily.
messages: Nucleus
messages: centrosome

9739:CHRNG
gene id: 9739:CHRNG
uniprot id: A0A6J3RP07
uniprot id: A0A6J3RPR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9739:EMC2
gene id: 9739:EMC2
uniprot id: A0A2U3V963
uniprot id: A0A2U4BXE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC2 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.

9739:LOC101323566
gene id: 9739:LOC101323566
uniprot id: A0A2U4B6A0
names: Similarity
messages: Belongs to the aldo/keto reductase family.

9739:AIMP2
gene id: 9739:AIMP2
uniprot id: A0A2U3V2Q3
uniprot id: A0A2U4AZA8
names: Subcellular Location Annotation
messages: Nucleus
messages: cytosol

9739:LOC101339557
gene id: 9739:LOC101339557
uniprot id: A0A6J3Q1K1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

9739:VWA2
gene id: 9739:VWA2
uniprot id: A0A6J3Q766
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:CLCN3
gene id: 9739:CLCN3
uniprot id: A0A2U4B3V4
uniprot id: A0A2U4B3W4
uniprot id: A0A2U4B3X4
uniprot id: A0A2U4B415
uniprot id: A0A2U4B4B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-3/CLCN3 subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

9739:LOC109552139
gene id: 9739:LOC109552139
uniprot id: A0A6J3S2T7
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.

9739:LOC101331121
gene id: 9739:LOC101331121
uniprot id: A0A6J3R1U1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9739:TNFSF11
gene id: 9739:TNFSF11
uniprot id: A0A2U4BFI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane
messages: Secreted

9739:LOC117309756
gene id: 9739:LOC117309756
uniprot id: A0A6J3QPG3
uniprot id: A0A6J3QQ43
names: Subcellular Location Annotation
messages: Cytoplasm
messages: nucleolus

9739:FADS3
gene id: 9739:FADS3
uniprot id: A0A6J3RPM4
uniprot id: A0A6J3RQ14
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

9739:JUP
gene id: 9739:JUP
uniprot id: A0A6J3QLV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: adherens junction

9739:PAQR7
gene id: 9739:PAQR7
uniprot id: A0A2U3V9W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

9739:NUP85
gene id: 9739:NUP85
uniprot id: A0A2U3V0I3
uniprot id: A0A6J3QM47
uniprot id: A0A6J3QML0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup85 family.
messages: Component of the nuclear pore complex (NPC).
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: nuclear pore complex

9739:ETV1
gene id: 9739:ETV1
uniprot id: A0A6J3RWH3
uniprot id: A0A6J3RWH7
uniprot id: A0A6J3RWI4
uniprot id: A0A6J3RWI7
uniprot id: A0A6J3RWI8
uniprot id: A0A6J3RWJ4
uniprot id: A0A6J3RWK3
uniprot id: A0A6J3RWK8
uniprot id: A0A6J3RWL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9739:CHD3
gene id: 9739:CHD3
uniprot id: A0A6J3QPZ8
uniprot id: A0A6J3QQ03
uniprot id: A0A6J3QQ08
uniprot id: A0A6J3QQ45
uniprot id: A0A6J3QQ50
uniprot id: A0A6J3QQ54
uniprot id: A0A6J3QQ59
uniprot id: A0A6J3QQP8
uniprot id: A0A6J3QQQ3
uniprot id: A0A6J3QQQ8
uniprot id: A0A6J3QQU3
uniprot id: A0A6J3QQU9
uniprot id: A0A6J3QQV4
uniprot id: A0A6J3QR83
uniprot id: A0A6J3QR89
uniprot id: A0A6J3QR94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

9739:SEPTIN1
gene id: 9739:SEPTIN1
uniprot id: A0A6J3Q0S7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

9739:UBE2E3
gene id: 9739:UBE2E3
uniprot id: A0A2U4B1P7
uniprot id: A0A2U4B1P9
uniprot id: A0A2U4B1T3
uniprot id: A0A2U4B1T7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9739:LOC117313387
gene id: 9739:LOC117313387
uniprot id: A0A6J3RE60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.
messages: Catalyzes viral DNA integration into the host chromosome, by performing a series of DNA cutting and joining reactions. This enzyme activity takes place after virion entry into a cell and reverse transcription of the RNA genome in dsDNA. The first step in the integration process is 3' processing. This step requires a complex comprising the viral genome, matrix protein and integrase. This complex is called the pre-integration complex (PIC). The integrase protein removes 2 nucleotides from each 3' end of the viral DNA, leaving recessed CA OH's at the 3' ends. In the second step that requires cell division, the PIC enters cell nucleus. In the third step, termed strand transfer, the integrase protein joins the previously processed 3' ends to the 5' ends of strands of target cellular DNA at the site of integration. The last step is viral DNA integration into host chromosome.
messages: Forms the spherical core of the virion that encapsulates the genomic RNA-nucleocapsid complex.
messages: Virion

9739:NTAQ1
gene id: 9739:NTAQ1
uniprot id: A0A2U3V5K1
uniprot id: A0A2U4B2Z9
uniprot id: A0A2U4B352
uniprot id: A0A2U4B3E8
uniprot id: A0A6J3QAU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NTAQ1 family.
messages: Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.
messages: Monomer.

9739:TGM1
gene id: 9739:TGM1
uniprot id: A0A6J3QZ51
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

9739:LOC101330643
gene id: 9739:LOC101330643
uniprot id: A0A2U4CFA3
names: Similarity
messages: Belongs to the MS4A family.

9739:KCND1
gene id: 9739:KCND1
uniprot id: A0A2U3VA37
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

9739:ACD
gene id: 9739:ACD
uniprot id: A0A6J3QCF3
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

9739:CXCR4
gene id: 9739:CXCR4
uniprot id: A0A2U3V7L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell junction
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Late endosome
messages: Lysosome
messages: Membrane

9739:MIF
gene id: 9739:MIF
uniprot id: A0A6J3PSR9
names: Similarity
messages: Belongs to the MIF family.

9739:C17H8orf82
gene id: 9739:C17H8orf82
uniprot id: A0A2U4BIF2
uniprot id: A0A6J3QA28
names: Similarity
messages: Belongs to the UPF0598 family.

9739:POPDC2
gene id: 9739:POPDC2
uniprot id: A0A2U3V6X7
uniprot id: A0A6J3RB20
names: Similarity
messages: Belongs to the popeye family.

9739:TMEM175
gene id: 9739:TMEM175
uniprot id: A0A6J3RCQ7
uniprot id: A0A6J3REJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

9739:PNMT
gene id: 9739:PNMT
uniprot id: A0A6J3QQS2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.

9739:NTSR1
gene id: 9739:NTSR1
uniprot id: A0A2U3UZ18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9739:PFDN6
gene id: 9739:PFDN6
uniprot id: A0A2U4B181
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

9739:PDGFRB
gene id: 9739:PDGFRB
uniprot id: A0A6J3R3F9
uniprot id: A0A6J3R426
uniprot id: A0A6J3R4C4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Interacts with homodimeric PDGFB and PDGFD, and with heterodimers formed by PDGFA and PDGFB.
messages: Lysosome lumen
messages: Membrane
messages: Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells.
messages: Vesicle

9739:TNFRSF4
gene id: 9739:TNFRSF4
uniprot id: A0A6J3QIS9
uniprot id: A0A6J3QJB6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:CSN3
gene id: 9739:CSN3
uniprot id: A0A2U3VA81
uniprot id: A0A2U4ARJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kappa-casein family.
messages: Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk.
messages: Secreted

9739:LOC101329046
gene id: 9739:LOC101329046
uniprot id: A0A2U3V308
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9739:GSTO1
gene id: 9739:GSTO1
uniprot id: A0A6J3Q5H3
uniprot id: A0A6J3Q5Q7
uniprot id: A0A6J3Q606
names: Function
names: Similarity
messages: Belongs to the GST superfamily. Omega family.
messages: Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA).

9739:BPI
gene id: 9739:BPI
uniprot id: A0A6J3Q0A0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

9739:SLC4A1
gene id: 9739:SLC4A1
uniprot id: A0A6J3QMG0
uniprot id: A0A6J3QN57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Membrane

9739:NIPSNAP1
gene id: 9739:NIPSNAP1
uniprot id: A0A2U4CKK9
names: Similarity
messages: Belongs to the NipSnap family.

9739:KLC1
gene id: 9739:KLC1
uniprot id: A0A2U4CNX9
uniprot id: A0A2U4CNZ2
uniprot id: A0A2U4CP00
uniprot id: A0A2U4CP23
uniprot id: A0A2U4CP25
uniprot id: A0A2U4CP34
uniprot id: A0A2U4CP41
uniprot id: A0A2U4CP48
uniprot id: A0A2U4CP63
uniprot id: A0A2U4CP66
uniprot id: A0A2U4CP95
uniprot id: A0A2U4CPC1
uniprot id: A0A2U4CPD5
uniprot id: A0A2U4CPJ4
uniprot id: A0A2U4CPL5
uniprot id: A0A6J3QVB9
uniprot id: A0A6J3QWB2
uniprot id: A0A6J3QX94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

9739:TBR1
gene id: 9739:TBR1
uniprot id: A0A2U4AAP3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9739:DNAJB14
gene id: 9739:DNAJB14
uniprot id: A0A2U4AM33
uniprot id: A0A2U4AM37
uniprot id: A0A2U4AM44
uniprot id: A0A2U4AM66
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:NAGK
gene id: 9739:NAGK
uniprot id: A0A2U3V0B5
uniprot id: A0A2U4BYI7
names: Similarity
messages: Belongs to the eukaryotic-type N-acetylglucosamine kinase family.

9739:UIMC1
gene id: 9739:UIMC1
uniprot id: A0A2U4BYL4
uniprot id: A0A2U4BYR4
uniprot id: A0A2U4BYR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAP80 family.
messages: Nucleus

9739:CRABP2
gene id: 9739:CRABP2
uniprot id: A0A6J3RET4
uniprot id: A0A6J3REU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm

9739:LOC101326346
gene id: 9739:LOC101326346
uniprot id: A0A6J3RG43
uniprot id: A0A6J3RHU2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:SLC25A33
gene id: 9739:SLC25A33
uniprot id: A0A2U4AZU1
uniprot id: A0A2U4B084
uniprot id: A0A6J3QBQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9739:TSPAN14
gene id: 9739:TSPAN14
uniprot id: A0A6J3Q7H5
uniprot id: A0A6J3Q7I1
uniprot id: A0A6J3Q7W4
uniprot id: A0A6J3Q8A7
uniprot id: A0A6J3Q8B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9739:AP4S1
gene id: 9739:AP4S1
uniprot id: A0A2U4AF98
uniprot id: A0A2U4AFQ1
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

9739:FUZ
gene id: 9739:FUZ
uniprot id: A0A6J3QFF3
uniprot id: A0A6J3QG29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fuzzy family.
messages: cytoskeleton

9739:TSR2
gene id: 9739:TSR2
uniprot id: A0A2U3V8H7
uniprot id: A0A2U4C1A7
names: Function
names: Similarity
messages: Belongs to the TSR2 family.
messages: May be involved in 20S pre-rRNA processing.

9739:CDKL3
gene id: 9739:CDKL3
uniprot id: A0A2U4AG99
names: Similarity
messages: Belongs to the protein kinase superfamily.

9739:LOC101322612
gene id: 9739:LOC101322612
uniprot id: A0A2U4C510
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9739:RPL23A
gene id: 9739:RPL23A
uniprot id: A0A2U4AVY9
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

9739:SLC28A3
gene id: 9739:SLC28A3
uniprot id: A0A2U4BRV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

9739:DIS3L
gene id: 9739:DIS3L
uniprot id: A0A2U4CFD1
uniprot id: A0A2U4CFD7
uniprot id: A0A2U4CFG6
uniprot id: A0A2U4CFJ4
uniprot id: A0A6J3QZ02
uniprot id: A0A6J3QZS3
names: Similarity
messages: Belongs to the RNR ribonuclease family.

9739:XRN2
gene id: 9739:XRN2
uniprot id: A0A2U4AQ80
uniprot id: A0A2U4AQM0
uniprot id: A0A6J3Q3T0
names: Function
names: Similarity
messages: Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
messages: Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.

9739:TMEM200C
gene id: 9739:TMEM200C
uniprot id: A0A2U4A5Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

9739:ADIPOR2
gene id: 9739:ADIPOR2
uniprot id: A0A2U4AKE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

9739:CES5A
gene id: 9739:CES5A
uniprot id: A0A6J3QGC5
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

9739:CTSC
gene id: 9739:CTSC
uniprot id: A0A2U4CFR5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C1 family.
messages: Lysosome
messages: Tetramer of heterotrimers consisting of exclusion domain, heavy- and light chains.

9739:PPIP5K2
gene id: 9739:PPIP5K2
uniprot id: A0A2U4BSY0
uniprot id: A0A2U4BSY7
uniprot id: A0A2U4BSZ1
uniprot id: A0A2U4BSZ5
uniprot id: A0A2U4BSZ6
uniprot id: A0A2U4BSZ9
uniprot id: A0A2U4BT00
uniprot id: A0A2U4BT51
uniprot id: A0A2U4BT57
uniprot id: A0A2U4BTA2
uniprot id: A0A2U4BTA7
uniprot id: A0A6J3R2I9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytosol

9739:IRF3
gene id: 9739:IRF3
uniprot id: A0A6J3QG01
names: Subcellular Location Annotation
messages: Nucleus

9739:ARL3
gene id: 9739:ARL3
uniprot id: A0A2U4BQP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

9739:NRM
gene id: 9739:NRM
uniprot id: A0A6J3RZ42
uniprot id: A0A6J3RZC5
uniprot id: A0A6J3S012
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nurim family.
messages: Membrane
messages: Nucleus inner membrane

9739:OPRM1
gene id: 9739:OPRM1
uniprot id: A0A2U3V1J2
uniprot id: A0A2U4CNW3
uniprot id: A0A2U4CNY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: axon
messages: dendrite

9739:TTR
gene id: 9739:TTR
uniprot id: A0A6J3PRN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transthyretin family.
messages: Homotetramer. Dimer of dimers. In the homotetramer, subunits assemble around a central channel that can accommodate two ligand molecules. Interacts with RBP4.
messages: Secreted
messages: Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.

9739:FADD
gene id: 9739:FADD
uniprot id: A0A2U4AUP3
names: Function
messages: Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.

9739:NUP62
gene id: 9739:NUP62
uniprot id: A0A6J3QGU0
names: Similarity
messages: Belongs to the nucleoporin NSP1/NUP62 family.

9739:GLYR1
gene id: 9739:GLYR1
uniprot id: A0A2U4ATM8
uniprot id: A0A6J3Q187
uniprot id: A0A6J3Q190
uniprot id: A0A6J3Q191
uniprot id: A0A6J3Q1C8
uniprot id: A0A6J3Q1D4
uniprot id: A0A6J3Q1J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HIBADH-related family. NP60 subfamily.
messages: Chromosome

9739:SLC30A1
gene id: 9739:SLC30A1
uniprot id: A0A2U3ZZ98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

9739:POLB
gene id: 9739:POLB
uniprot id: A0A2U3UZ93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Cytoplasm
messages: DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
messages: Nucleus

9739:POSTN
gene id: 9739:POSTN
uniprot id: A0A2U4BGE7
uniprot id: A0A2U4BGE8
uniprot id: A0A2U4BGE9
uniprot id: A0A2U4BGF3
uniprot id: A0A2U4BGI5
uniprot id: A0A2U4BGT6
names: Subcellular Location Annotation
messages: extracellular matrix

9739:QTRT1
gene id: 9739:QTRT1
uniprot id: A0A2U3UYY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1' of the ribose to form the product.
messages: Cytoplasm
messages: Heterodimer of a catalytic subunit QTRT1 and an accessory subunit QTRT2.
messages: Mitochondrion outer membrane

9739:LOC101334087
gene id: 9739:LOC101334087
uniprot id: A0A6J3QKT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

9739:FAHD1
gene id: 9739:FAHD1
uniprot id: A0A2U3V4M2
names: Similarity
messages: Belongs to the FAH family.

9739:TNFAIP1
gene id: 9739:TNFAIP1
uniprot id: A0A2U3V151
names: Similarity
messages: Belongs to the BACURD family.

9739:DOLK
gene id: 9739:DOLK
uniprot id: A0A2U3VAF6
names: Similarity
messages: Belongs to the polyprenol kinase family.

9739:SERF1A
gene id: 9739:SERF1A
uniprot id: A0A2U4AWW6
names: Similarity
messages: Belongs to the SERF family.

9739:CPSF3
gene id: 9739:CPSF3
uniprot id: A0A2U4C079
uniprot id: A0A2U4C0B9
uniprot id: A0A2U4C0C0
uniprot id: A0A2U4C0C4
names: Subcellular Location Annotation
messages: Nucleus

9739:CMAS
gene id: 9739:CMAS
uniprot id: A0A2U3V7G0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CMP-NeuNAc synthase family.
messages: Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN).
messages: Homotetramer; the active enzyme is formed by a dimer of dimers.

9739:LOC101323957
gene id: 9739:LOC101323957
uniprot id: A0A6J3RM34
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

9739:HCAR1
gene id: 9739:HCAR1
uniprot id: A0A2U4CKM0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9739:SBNO2
gene id: 9739:SBNO2
uniprot id: A0A6J3R7U1
uniprot id: A0A6J3R7U6
uniprot id: A0A6J3R895
uniprot id: A0A6J3R8S5
uniprot id: A0A6J3R8T1
uniprot id: A0A6J3RAK7
names: Similarity
messages: Belongs to the SBNO family.

9739:LOC101338323
gene id: 9739:LOC101338323
uniprot id: A0A6J3QT86
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

9739:BCL9
gene id: 9739:BCL9
uniprot id: A0A6J3RP45
uniprot id: A0A6J3RPV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCL9 family.
messages: Nucleus

9739:LOC101338167
gene id: 9739:LOC101338167
uniprot id: A0A2U4A4R3
names: Similarity
messages: Belongs to the COX20 family.

9739:CNN3
gene id: 9739:CNN3
uniprot id: A0A2U4A1L1
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

9739:SLC6A5
gene id: 9739:SLC6A5
uniprot id: A0A6J3RVE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

9739:ODF2L
gene id: 9739:ODF2L
uniprot id: A0A2U4A3T2
uniprot id: A0A6J3RZ10
uniprot id: A0A6J3RZ64
uniprot id: A0A6J3RZU8
uniprot id: A0A6J3RZV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

9739:PACC1
gene id: 9739:PACC1
uniprot id: A0A6J3R2L7
uniprot id: A0A6J3R349
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proton-activated chloride channel family.
messages: Cell membrane
messages: Membrane

9739:CNNM3
gene id: 9739:CNNM3
uniprot id: A0A6J3PW62
uniprot id: A0A6J3PW69
uniprot id: A0A6J3PW74
uniprot id: A0A6J3PWC9
uniprot id: A0A6J3PWF3
uniprot id: A0A6J3PWT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Cell membrane
messages: Membrane
messages: Metal transporter.

9739:EXOC3L1
gene id: 9739:EXOC3L1
uniprot id: A0A6J3QHZ3
names: Similarity
messages: Belongs to the SEC6 family.

9739:LOC101326738
gene id: 9739:LOC101326738
uniprot id: A0A6J3QVA8
names: Subcellular Location Annotation
messages: Cytoplasm

9739:MB
gene id: 9739:MB
uniprot id: A0A6J3S3Q6
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

9739:SLC4A10
gene id: 9739:SLC4A10
uniprot id: A0A2U4A9T5
uniprot id: A0A2U4A9W3
uniprot id: A0A2U4AAI8
uniprot id: A0A6J3RMF8
uniprot id: A0A6J3RMG2
uniprot id: A0A6J3RMS5
uniprot id: A0A6J3RN76
uniprot id: A0A6J3RN80
uniprot id: A0A6J3RN84
uniprot id: A0A6J3RNP1
uniprot id: A0A6J3RNP6
uniprot id: A0A6J3RNQ1
uniprot id: A0A6J3RNW4
uniprot id: A0A6J3RNW9
uniprot id: A0A6J3RNX1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lateral cell membrane
messages: Membrane

9739:FIP1L1
gene id: 9739:FIP1L1
uniprot id: A0A2U3V6D5
uniprot id: A0A2U3V6R8
uniprot id: A0A2U4ARY6
uniprot id: A0A2U4ARZ0
uniprot id: A0A2U4ARZ2
uniprot id: A0A2U4ARZ5
uniprot id: A0A2U4AS03
uniprot id: A0A2U4AS08
uniprot id: A0A2U4ASF4
uniprot id: A0A2U4ASF9
uniprot id: A0A6J3RDQ9
uniprot id: A0A6J3RDR1
uniprot id: A0A6J3RDR5
uniprot id: A0A6J3RDR6
uniprot id: A0A6J3RDS0
uniprot id: A0A6J3RDS1
uniprot id: A0A6J3RDS5
uniprot id: A0A6J3RDT3
uniprot id: A0A6J3REA7
uniprot id: A0A6J3REB2
uniprot id: A0A6J3REB7
uniprot id: A0A6J3REC4
uniprot id: A0A6J3REK1
uniprot id: A0A6J3REK6
uniprot id: A0A6J3REL2
uniprot id: A0A6J3RG11
uniprot id: A0A6J3RG15
uniprot id: A0A6J3RG21
uniprot id: A0A6J3RG27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIP1 family.
messages: Nucleus

9739:LOC101327549
gene id: 9739:LOC101327549
uniprot id: A0A6J3S6J4
names: Similarity
messages: Belongs to the intermediate filament family.

9739:TMA7
gene id: 9739:TMA7
uniprot id: A0A2U3UZW4
names: Similarity
messages: Belongs to the TMA7 family.

9739:RNASE4
gene id: 9739:RNASE4
uniprot id: A0A2U4BC43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

9739:GLB1L
gene id: 9739:GLB1L
uniprot id: A0A2U3V4W7
uniprot id: A0A2U4BMM8
uniprot id: A0A2U4BMM9
uniprot id: A0A6J3RLZ0
uniprot id: A0A6J3RN26
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

9739:KDM3B
gene id: 9739:KDM3B
uniprot id: A0A2U4AGD7
uniprot id: A0A2U4AGE9
uniprot id: A0A2U4AGF8
uniprot id: A0A2U4AGL9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM2 histone demethylase family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code.
messages: Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors.
messages: Nucleus
messages: The JmjC domain and the C6-type zinc-finger are required for the demethylation activity.

9739:QPRT
gene id: 9739:QPRT
uniprot id: A0A2U4A8R2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

9739:IMPA2
gene id: 9739:IMPA2
uniprot id: A0A6J3PTC1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

9739:SEC23A
gene id: 9739:SEC23A
uniprot id: A0A6J3QY21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

9739:LDLR
gene id: 9739:LDLR
uniprot id: A0A6J3R5T6
uniprot id: A0A6J3R6S5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:LOC101339383
gene id: 9739:LOC101339383
uniprot id: A0A6J3RT40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.

9739:NDUFS7
gene id: 9739:NDUFS7
uniprot id: A0A6J3R8P0
uniprot id: A0A6J3R8P6
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

9739:AK1
gene id: 9739:AK1
uniprot id: A0A6J3RJH9
uniprot id: A0A6J3RKH2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK1 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

9739:KCNS3
gene id: 9739:KCNS3
uniprot id: A0A2U4C090
names: Subcellular Location Annotation
messages: Membrane

9739:SARS1
gene id: 9739:SARS1
uniprot id: A0A2U4A3A1
uniprot id: A0A2U4A3B7
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.

9739:GNG8
gene id: 9739:GNG8
uniprot id: A0A6J3QFC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

9739:CHN2
gene id: 9739:CHN2
uniprot id: A0A2U4ALK9
uniprot id: A0A2U4ALV8
uniprot id: A0A6J3RWS6
names: Function
messages: GTPase-activating protein for p21-rac.

9739:LOC117313329
gene id: 9739:LOC117313329
uniprot id: A0A6J3RSK0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9739:ABCC8
gene id: 9739:ABCC8
uniprot id: A0A2U4CF34
uniprot id: A0A6J3RV90
uniprot id: A0A6J3RV94
uniprot id: A0A6J3RVA5
uniprot id: A0A6J3RVB0
uniprot id: A0A6J3RVD1
uniprot id: A0A6J3RVD7
uniprot id: A0A6J3RVD8
uniprot id: A0A6J3RVU6
uniprot id: A0A6J3RVV2
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with KCNJ11.
messages: Membrane

9739:FAR2
gene id: 9739:FAR2
uniprot id: A0A2U4BDX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acyl-CoA reductase family.
messages: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
messages: Peroxisome membrane

9739:ALOX5
gene id: 9739:ALOX5
uniprot id: A0A6J3Q6C7
uniprot id: A0A6J3Q6H4
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:PLA2G2C
gene id: 9739:PLA2G2C
uniprot id: A0A6J3PXH6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

9739:TRIM9
gene id: 9739:TRIM9
uniprot id: A0A2U4AFV6
names: Subcellular Location Annotation
messages: cytoskeleton

9739:GABRA4
gene id: 9739:GABRA4
uniprot id: A0A2U3V438
uniprot id: A0A2U3V470
uniprot id: A0A2U3V4J7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9739:FAM3B
gene id: 9739:FAM3B
uniprot id: A0A6J3RBM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

9739:THOC5
gene id: 9739:THOC5
uniprot id: A0A2U4CKK4
uniprot id: A0A2U4CKK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC5 family.
messages: Nucleus

9739:RAB5IF
gene id: 9739:RAB5IF
uniprot id: A0A2U3V2W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:MTHFS
gene id: 9739:MTHFS
uniprot id: A0A2U4C7R9
uniprot id: A0A6J3R0F5
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

9739:GABARAPL2
gene id: 9739:GABARAPL2
uniprot id: A0A2U3V0S5
names: Similarity
messages: Belongs to the ATG8 family.

9739:HMGCS1
gene id: 9739:HMGCS1
uniprot id: A0A2U4AXV7
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

9739:SLC10A7
gene id: 9739:SLC10A7
uniprot id: A0A6J3REL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Golgi apparatus membrane

9739:NCAPH
gene id: 9739:NCAPH
uniprot id: A0A2U4B0D0
uniprot id: A0A2U4B0G3
uniprot id: A0A6J3PV55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND2 (condensin subunit 2) family.
messages: Chromosome
messages: Cytoplasm
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.

9739:CCL15
gene id: 9739:CCL15
uniprot id: A0A2U4C6K2
uniprot id: A0A2U4C6U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

9739:SMUG1
gene id: 9739:SMUG1
uniprot id: A0A6J3S6A2
uniprot id: A0A6J3S7D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. SMUG1 family.
messages: Nucleus

9739:MCHR2
gene id: 9739:MCHR2
uniprot id: A0A2U4AVR2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9739:RDH8
gene id: 9739:RDH8
uniprot id: A0A6J3RB58
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9739:LOC117312159
gene id: 9739:LOC117312159
uniprot id: A0A6J3RAI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TET family.
messages: Nucleus

9739:ARL2BP
gene id: 9739:ARL2BP
uniprot id: A0A6J3QDS3
uniprot id: A0A6J3QE93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARL2BP family.
messages: Cytoplasm
messages: Mitochondrion intermembrane space
messages: Nucleus
messages: Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2.
messages: centrosome
messages: cilium basal body

9739:ARF1
gene id: 9739:ARF1
uniprot id: A0A6J3R481
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

9739:GMPR
gene id: 9739:GMPR
uniprot id: A0A2U4C4Z4
uniprot id: A0A6J3RYS3
uniprot id: A0A6J3RYV2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:TIMM44
gene id: 9739:TIMM44
uniprot id: A0A6J3R6X0
uniprot id: A0A6J3R942
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tim44 family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion inner membrane

9739:DVL1
gene id: 9739:DVL1
uniprot id: A0A6J3QG84
uniprot id: A0A6J3QG92
names: Similarity
messages: Belongs to the DSH family.

9739:CADM1
gene id: 9739:CADM1
uniprot id: A0A2U4BW42
uniprot id: A0A2U4BW93
names: Similarity
messages: Belongs to the nectin family.

9739:LOC101336875
gene id: 9739:LOC101336875
uniprot id: A0A2U4C6K8
uniprot id: A0A6J3R3R9
uniprot id: A0A6J3R4Q1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:CLDN10
gene id: 9739:CLDN10
uniprot id: A0A2U4A633
uniprot id: A0A6J3QB72
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9739:MAPK14
gene id: 9739:MAPK14
uniprot id: A0A2U4CIE8
uniprot id: A0A2U4CIF3
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

9739:PPP1R15A
gene id: 9739:PPP1R15A
uniprot id: A0A6J3QJ90
names: Similarity
messages: Belongs to the PPP1R15 family.

9739:ACP1
gene id: 9739:ACP1
uniprot id: A0A2U3V8R5
uniprot id: A0A2U3V8U2
uniprot id: A0A6J3PV25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates.
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
messages: Cytoplasm

9739:TNRC6B
gene id: 9739:TNRC6B
uniprot id: A0A2U4C1I3
uniprot id: A0A2U4C1I6
uniprot id: A0A2U4C1J4
uniprot id: A0A2U4C1J6
uniprot id: A0A2U4C1L5
uniprot id: A0A2U4C1S8
names: Similarity
messages: Belongs to the GW182 family.

9739:STAG1
gene id: 9739:STAG1
uniprot id: A0A2U4B985
uniprot id: A0A2U4B9D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

9739:FKRP
gene id: 9739:FKRP
uniprot id: A0A6J3QF66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LicD transferase family.
messages: Golgi apparatus membrane

9739:PRMT7
gene id: 9739:PRMT7
uniprot id: A0A2U4BDA2
uniprot id: A0A2U4BDB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.
messages: Nucleus
messages: cytosol

9739:GPR183
gene id: 9739:GPR183
uniprot id: A0A2U4A5Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9739:SSTR5
gene id: 9739:SSTR5
uniprot id: A0A6J3Q2F7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9739:DIO2
gene id: 9739:DIO2
uniprot id: A0A2U4A440
names: Function
names: Similarity
messages: Belongs to the iodothyronine deiodinase family.
messages: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).

9739:LOC101337977
gene id: 9739:LOC101337977
uniprot id: A0A6J3RP56
names: Subcellular Location Annotation
messages: Membrane

9739:LOC117313327
gene id: 9739:LOC117313327
uniprot id: A0A6J3RSX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9739:PODXL2
gene id: 9739:PODXL2
uniprot id: A0A2U3V5R8
names: Subcellular Location Annotation
messages: Membrane

9739:ESRRG
gene id: 9739:ESRRG
uniprot id: A0A2U3UZV9
uniprot id: A0A2U3V0B1
uniprot id: A0A2U4A4F3
uniprot id: A0A2U4A4I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

9739:LOC109552358
gene id: 9739:LOC109552358
uniprot id: A0A6J3QSF5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.

9739:SLC4A3
gene id: 9739:SLC4A3
uniprot id: A0A6J3RMI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Membrane

9739:G6PC3
gene id: 9739:G6PC3
uniprot id: A0A6J3QP59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

9739:ACAD9
gene id: 9739:ACAD9
uniprot id: A0A6J3S3G7
uniprot id: A0A6J3S487
uniprot id: A0A6J3S4H9
uniprot id: A0A6J3S4I4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

9739:CD200R1
gene id: 9739:CD200R1
uniprot id: A0A2U3V482
names: Similarity
messages: Belongs to the CD200R family.

9739:LOC101337968
gene id: 9739:LOC101337968
uniprot id: A0A6J3RPL0
uniprot id: A0A6J3RQR6
names: Subcellular Location Annotation
messages: Membrane

9739:LOC117311033
gene id: 9739:LOC117311033
uniprot id: A0A6J3QX04
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:DDA1
gene id: 9739:DDA1
uniprot id: A0A6J3R4R6
uniprot id: A0A6J3R5N0
names: Similarity
messages: Belongs to the DDA1 family.

9739:DRD5
gene id: 9739:DRD5
uniprot id: A0A6J3RFH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9739:CREBBP
gene id: 9739:CREBBP
uniprot id: A0A6J3Q1L8
uniprot id: A0A6J3Q1L9
uniprot id: A0A6J3Q1M3
uniprot id: A0A6J3Q1M5
uniprot id: A0A6J3Q1R8
uniprot id: A0A6J3Q1W9
uniprot id: A0A6J3Q280
names: Subcellular Location Annotation
messages: Cytoplasm

9739:MMP2
gene id: 9739:MMP2
uniprot id: A0A2U3V2T7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.
messages: extracellular matrix

9739:PSMC3IP
gene id: 9739:PSMC3IP
uniprot id: A0A6J3QP72
uniprot id: A0A6J3QPP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HOP2 family.
messages: Nucleus

9739:SEMA3C
gene id: 9739:SEMA3C
uniprot id: A0A2U4BSE0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9739:TM4SF1
gene id: 9739:TM4SF1
uniprot id: A0A2U3VAL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

9739:LOC101339947
gene id: 9739:LOC101339947
uniprot id: A0A6J3R9H3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Membrane

9739:RABGGTB
gene id: 9739:RABGGTB
uniprot id: A0A2U4A380
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.

9739:CIAO2B
gene id: 9739:CIAO2B
uniprot id: A0A6J3QD05
names: Similarity
messages: Belongs to the MIP18 family.

9739:PREP
gene id: 9739:PREP
uniprot id: A0A2U4AVR1
names: Similarity
messages: Belongs to the peptidase S9A family.

9739:DIO1
gene id: 9739:DIO1
uniprot id: A0A2U4BJB8
names: Function
names: Similarity
messages: Belongs to the iodothyronine deiodinase family.
messages: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).

9739:WT1
gene id: 9739:WT1
uniprot id: A0A2U4CDE4
uniprot id: A0A2U4CDE6
uniprot id: A0A2U4CDE7
uniprot id: A0A2U4CDF8
uniprot id: A0A2U4CDF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Cytoplasm
messages: Nucleus speckle

9739:ALX3
gene id: 9739:ALX3
uniprot id: A0A2U4A2T9
names: Subcellular Location Annotation
messages: Nucleus

9739:POLR1D
gene id: 9739:POLR1D
uniprot id: A0A6J3QBT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Component of the RNA polymerase I (Pol I) and RNA polymerase III (Pol III) complexes consisting of at least 13 and 17 subunits, respectively.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively.

9739:PLAC1
gene id: 9739:PLAC1
uniprot id: A0A6J3QVF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PLAC1 family.
messages: Secreted

9739:STXBP1
gene id: 9739:STXBP1
uniprot id: A0A6J3RIF7
uniprot id: A0A6J3RIR6
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

9739:LOC117314494
gene id: 9739:LOC117314494
uniprot id: A0A6J3S9Q9
names: Similarity
messages: Belongs to the heat shock protein 70 family.

9739:PPP1R3E
gene id: 9739:PPP1R3E
uniprot id: A0A2U3V8I9
uniprot id: A0A2U4CFD3
uniprot id: A0A6J3QYH0
names: Subcellular Location Annotation
messages: Nucleus

9739:LAMA5
gene id: 9739:LAMA5
uniprot id: A0A6J3Q1W4
uniprot id: A0A6J3Q248
uniprot id: A0A6J3Q2H5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

9739:ALAS1
gene id: 9739:ALAS1
uniprot id: A0A2U3V073
uniprot id: A0A2U4CCP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion inner membrane

9739:CDH6
gene id: 9739:CDH6
uniprot id: A0A2U4AXV1
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

9739:EDN1
gene id: 9739:EDN1
uniprot id: A0A2U3V1P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

9739:PPP3CC
gene id: 9739:PPP3CC
uniprot id: A0A6J3RFP9
uniprot id: A0A6J3RG73
uniprot id: A0A6J3RGI1
uniprot id: A0A6J3RHX4
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

9739:HVCN1
gene id: 9739:HVCN1
uniprot id: A0A2U3UYR2
uniprot id: A0A2U4CKV6
uniprot id: A0A2U4CKV8
uniprot id: A0A2U4CL36
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hydrogen channel family.
messages: Homodimer.
messages: Membrane

9739:MRPL14
gene id: 9739:MRPL14
uniprot id: A0A2U4CJ67
uniprot id: A0A2U4CJ71
uniprot id: A0A2U4CJG1
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

9739:KCNJ1
gene id: 9739:KCNJ1
uniprot id: A0A2U4BWL2
uniprot id: A0A2U4BWR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

9739:FAM234A
gene id: 9739:FAM234A
uniprot id: A0A6J3PYT5
uniprot id: A0A6J3PZD7
names: Similarity
messages: Belongs to the FAM234 family.

9739:EDEM1
gene id: 9739:EDEM1
uniprot id: A0A2U4CCL6
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

9739:ARAP1
gene id: 9739:ARAP1
uniprot id: A0A6J3RUB9
uniprot id: A0A6J3RUC5
uniprot id: A0A6J3RUK7
uniprot id: A0A6J3RUL2
uniprot id: A0A6J3RUQ3
uniprot id: A0A6J3RUQ7
uniprot id: A0A6J3RUR0
uniprot id: A0A6J3RUR3
uniprot id: A0A6J3RUR7
uniprot id: A0A6J3RV38
uniprot id: A0A6J3RV43
names: Subcellular Location Annotation
messages: Cytoplasm

9739:GNA12
gene id: 9739:GNA12
uniprot id: A0A2U4CBX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

9739:ASIC2
gene id: 9739:ASIC2
uniprot id: A0A6J3QN08
uniprot id: A0A6J3QNF5
names: Subcellular Location Annotation
messages: Membrane

9739:RPL10L
gene id: 9739:RPL10L
uniprot id: A0A2U4AFW1
uniprot id: A0A2U4AGB8
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

9739:LOC117308815
gene id: 9739:LOC117308815
uniprot id: A0A6J3QAM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing.
messages: cytosol

9739:ST6GALNAC6
gene id: 9739:ST6GALNAC6
uniprot id: A0A2U4CHF0
uniprot id: A0A6J3RIH5
uniprot id: A0A6J3RII0
uniprot id: A0A6J3RIT2
uniprot id: A0A6J3RKH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9739:SCMH1
gene id: 9739:SCMH1
uniprot id: A0A2U4BK17
uniprot id: A0A2U4BK18
uniprot id: A0A6J3PRN9
uniprot id: A0A6J3PRW4
uniprot id: A0A6J3PRX8
uniprot id: A0A6J3PRY8
uniprot id: A0A6J3PSC9
uniprot id: A0A6J3PT09
uniprot id: A0A6J3PT14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

9739:P3H3
gene id: 9739:P3H3
uniprot id: A0A6J3S994
names: Similarity
messages: Belongs to the leprecan family.

9739:IFRD1
gene id: 9739:IFRD1
uniprot id: A0A6J3RWW4
uniprot id: A0A6J3RXK0
names: Similarity
messages: Belongs to the IFRD family.

9739:FAM160B2
gene id: 9739:FAM160B2
uniprot id: A0A6J3RFR3
uniprot id: A0A6J3RFV6
uniprot id: A0A6J3RG83
uniprot id: A0A6J3RG88
uniprot id: A0A6J3RHY3
uniprot id: A0A6J3RHY7
names: Similarity
messages: Belongs to the FHIP family.

9739:BARX1
gene id: 9739:BARX1
uniprot id: A0A2U3V645
names: Subcellular Location Annotation
messages: Nucleus

9739:MTX3
gene id: 9739:MTX3
uniprot id: A0A2U3V8N1
uniprot id: A0A2U3V8Q4
uniprot id: A0A2U4AWI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

9739:TSNAX
gene id: 9739:TSNAX
uniprot id: A0A2U4BV98
uniprot id: A0A2U4BV99
uniprot id: A0A2U4BVH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the translin family.
messages: Nucleus

9739:B3GALT4
gene id: 9739:B3GALT4
uniprot id: A0A2U3VAN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9739:COPZ2
gene id: 9739:COPZ2
uniprot id: A0A6J3QNW4
uniprot id: A0A6J3QNZ6
uniprot id: A0A6J3QPG0
uniprot id: A0A6J3QPQ9
uniprot id: A0A6J3QPR4
uniprot id: A0A6J3QQ37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

9739:TM9SF1
gene id: 9739:TM9SF1
uniprot id: A0A2U4AFE0
uniprot id: A0A2U4AFE6
uniprot id: A0A6J3QXB5
uniprot id: A0A6J3QXM2
uniprot id: A0A6J3QXS7
uniprot id: A0A6J3QXT2
uniprot id: A0A6J3QZ58
uniprot id: A0A6J3QZ65
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF7 family.
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:MZF1
gene id: 9739:MZF1
uniprot id: A0A6J3QE95
uniprot id: A0A6J3QES5
names: Subcellular Location Annotation
messages: Nucleus

9739:HS2ST1
gene id: 9739:HS2ST1
uniprot id: A0A6J3RYS2
uniprot id: A0A6J3RYS7
uniprot id: A0A6J3RZN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Golgi apparatus membrane
messages: Membrane

9739:FAHD2A
gene id: 9739:FAHD2A
uniprot id: A0A6J3PVS9
uniprot id: A0A6J3PVT3
uniprot id: A0A6J3PW17
uniprot id: A0A6J3PWE3
names: Similarity
messages: Belongs to the FAH family.

9739:EXTL1
gene id: 9739:EXTL1
uniprot id: A0A6J3Q399
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:LOC101317496
gene id: 9739:LOC101317496
uniprot id: A0A6J3S8P1
names: Similarity
messages: Belongs to the GroES chaperonin family.

9739:ACOT13
gene id: 9739:ACOT13
uniprot id: A0A2U4C5I5
names: Similarity
messages: Belongs to the thioesterase PaaI family.

9739:CASP8
gene id: 9739:CASP8
uniprot id: A0A2U4BNA7
uniprot id: A0A2U4BNM8
names: Similarity
messages: Belongs to the peptidase C14A family.

9739:PRKCI
gene id: 9739:PRKCI
uniprot id: A0A2U4C875
uniprot id: A0A2U4C879
uniprot id: A0A2U4C8G1
uniprot id: A0A6J3R9S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

9739:ADGRE3
gene id: 9739:ADGRE3
uniprot id: A0A2U4B8M1
uniprot id: A0A2U4B8T6
uniprot id: A0A6J3R5P5
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:LOC101322931
gene id: 9739:LOC101322931
uniprot id: A0A2U4A4I8
names: Similarity
messages: Belongs to the histone H3 family.

9739:PPM1F
gene id: 9739:PPM1F
uniprot id: A0A6J3PST8
uniprot id: A0A6J3PTX6
names: Similarity
messages: Belongs to the PP2C family.

9739:EDC3
gene id: 9739:EDC3
uniprot id: A0A2U4CI83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EDC3 family.
messages: P-body

9739:LOC101334217
gene id: 9739:LOC101334217
uniprot id: A0A2U4A2H6
names: Similarity
messages: Belongs to the CLCR family.

9739:GPR50
gene id: 9739:GPR50
uniprot id: A0A2U4BNL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9739:GDI2
gene id: 9739:GDI2
uniprot id: A0A2U4B6B9
uniprot id: A0A2U4B6R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

9739:CAMSAP3
gene id: 9739:CAMSAP3
uniprot id: A0A6J3R6J9
uniprot id: A0A6J3R702
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

9739:NIFK
gene id: 9739:NIFK
uniprot id: A0A2U3V9D8
names: Subcellular Location Annotation
messages: nucleolus

9739:LSR
gene id: 9739:LSR
uniprot id: A0A6J3QF20
uniprot id: A0A6J3QF42
uniprot id: A0A6J3QFK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

9739:LOC101316233
gene id: 9739:LOC101316233
uniprot id: A0A6J3Q8N6
names: Subcellular Location Annotation
messages: Nucleus

9739:SV2B
gene id: 9739:SV2B
uniprot id: A0A2U4C7W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

9739:LOC101334385
gene id: 9739:LOC101334385
uniprot id: A0A6J3RJ93
names: Similarity
messages: Belongs to the SPATA31 family.

9739:SERP1
gene id: 9739:SERP1
uniprot id: A0A2U3V4J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.
messages: Membrane

9739:TAS2R1
gene id: 9739:TAS2R1
uniprot id: A0A2U4CMK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

9739:LOC109550730
gene id: 9739:LOC109550730
uniprot id: A0A6J3QE92
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

9739:SLC34A1
gene id: 9739:SLC34A1
uniprot id: A0A6J3R875
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Membrane

9739:SNF8
gene id: 9739:SNF8
uniprot id: A0A2U4AHN0
uniprot id: A0A2U4AHQ2
uniprot id: A0A2U4AI61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF8 family.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).

9739:LOC117313234
gene id: 9739:LOC117313234
uniprot id: A0A6J3RS15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GST superfamily. Pi family.
messages: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
messages: Cytoplasm
messages: Homodimer.
messages: Mitochondrion
messages: Nucleus

9739:SH3BP5
gene id: 9739:SH3BP5
uniprot id: A0A2U4BA62
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

9739:FOXI2
gene id: 9739:FOXI2
uniprot id: A0A2U4BQ06
names: Subcellular Location Annotation
messages: Nucleus

9739:LOC101331097
gene id: 9739:LOC101331097
uniprot id: A0A6J3RPV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PCNA family.
messages: Nucleus
messages: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

9739:BCL2L10
gene id: 9739:BCL2L10
uniprot id: A0A2U4C9Q7
names: Similarity
messages: Belongs to the Bcl-2 family.

9739:MARK4
gene id: 9739:MARK4
uniprot id: A0A6J3QEW8
uniprot id: A0A6J3QFC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

9739:PGLYRP2
gene id: 9739:PGLYRP2
uniprot id: A0A6J3R4N7
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

9739:HSD17B4
gene id: 9739:HSD17B4
uniprot id: A0A6J3R2M0
uniprot id: A0A6J3R2R4
uniprot id: A0A6J3R359
names: Subcellular Location Annotation
messages: Peroxisome

9739:SLC16A6
gene id: 9739:SLC16A6
uniprot id: A0A6J3QK01
uniprot id: A0A6J3QKF5
names: Subcellular Location Annotation
messages: Membrane

9739:BHLHB9
gene id: 9739:BHLHB9
uniprot id: A0A2U4CHL9
names: Similarity
messages: Belongs to the GPRASP family.

9739:TLR6
gene id: 9739:TLR6
uniprot id: A0A2U4ASI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

9739:LOC101324847
gene id: 9739:LOC101324847
uniprot id: A0A2U3V6N9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

9739:MAP4K2
gene id: 9739:MAP4K2
uniprot id: A0A6J3RQ88
uniprot id: A0A6J3RQL7
uniprot id: A0A6J3RQN7
uniprot id: A0A6J3RR91
uniprot id: A0A6J3RR95
uniprot id: A0A6J3RR99
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

9739:LOC101328029
gene id: 9739:LOC101328029
uniprot id: A0A6J3RXI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the C19orf12 family.
messages: Mitochondrion membrane

9739:PHF20
gene id: 9739:PHF20
uniprot id: A0A2U4CLZ3
uniprot id: A0A6J3PXW1
uniprot id: A0A6J3PY34
names: Subcellular Location Annotation
messages: Nucleus

9739:CIAO2A
gene id: 9739:CIAO2A
uniprot id: A0A2U3V1B1
uniprot id: A0A2U4CDL3
names: Similarity
messages: Belongs to the MIP18 family.

9739:PLAU
gene id: 9739:PLAU
uniprot id: A0A2U4BED9
uniprot id: A0A2U4BEE7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:EIF2B2
gene id: 9739:EIF2B2
uniprot id: A0A2U4A6E8
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

9739:IRF4
gene id: 9739:IRF4
uniprot id: A0A2U4C5Q0
uniprot id: A0A6J3RYJ6
uniprot id: A0A6J3RZE6
names: Subcellular Location Annotation
messages: Nucleus

9739:CAPN11
gene id: 9739:CAPN11
uniprot id: A0A6J3RY97
names: Similarity
messages: Belongs to the peptidase C2 family.

9739:SIX2
gene id: 9739:SIX2
uniprot id: A0A2U4BXT7
uniprot id: A0A6J3PWP9
names: Subcellular Location Annotation
messages: Nucleus

9739:CLPP
gene id: 9739:CLPP
uniprot id: A0A6J3R9F0
names: Similarity
messages: Belongs to the peptidase S14 family.

9739:LOC101324864
gene id: 9739:LOC101324864
uniprot id: A0A2U4AGX5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9739:ABCB4
gene id: 9739:ABCB4
uniprot id: A0A2U4AU09
uniprot id: A0A2U4AU27
uniprot id: A0A2U4AU39
uniprot id: A0A2U4AU48
uniprot id: A0A2U4AU62
uniprot id: A0A2U4AU68
uniprot id: A0A2U4AUJ4
uniprot id: A0A6J3RWA9
uniprot id: A0A6J3RWD9
uniprot id: A0A6J3RWX2
names: Subcellular Location Annotation
messages: Membrane

9739:AOC1
gene id: 9739:AOC1
uniprot id: A0A6J3RVN1
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

9739:LYRM1
gene id: 9739:LYRM1
uniprot id: A0A2U4A9P4
names: Similarity
messages: Belongs to the complex I LYR family.

9739:LEP
gene id: 9739:LEP
uniprot id: A0A6J3RVM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the leptin family.
messages: Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, increases basal metabolism, influences reproductive function, regulates pancreatic beta-cell function and insulin secretion, is pro-angiogenic for endothelial cell and affects innate and adaptive immunity. In the arcuate nucleus of the hypothalamus, activates by depolarization POMC neurons inducing FOS and SOCS3 expression to release anorexigenic peptides and inhibits by hyperpolarization NPY neurons inducing SOCS3 with a consequent reduction on release of orexigenic peptides. In addition to its known satiety inducing effect, has a modulatory role in nutrient absorption. In the intestine, reduces glucose absorption by enterocytes by activating PKC and leading to a sequential activation of p38, PI3K and ERK signaling pathways which exerts an inhibitory effect on glucose absorption. Acts as a growth factor on certain tissues, through the activation of different signaling pathways increases expression of genes involved in cell cycle regulation such as CCND1, via JAK2-STAT3 pathway, or VEGFA, via MAPK1/3 and PI3K-AKT1 pathways. May also play an apoptotic role via JAK2-STAT3 pathway and up-regulation of BIRC5 expression. Pro-angiogenic, has mitogenic activity on vascular endothelial cells and plays a role in matrix remodeling by regulating the expression of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs). In innate immunity, modulates the activity and function of neutrophils by in…
messages: Secreted

9739:ADK
gene id: 9739:ADK
uniprot id: A0A2U4BED3
uniprot id: A0A2U4BED5
uniprot id: A0A2U4BEG6
uniprot id: A0A2U4BEH1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Monomer.
messages: Nucleus

9739:FBXO48
gene id: 9739:FBXO48
uniprot id: A0A2U3VA02
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complex SCF(FBXO9) composed of CUL1, SKP1, RBX1 and FBXO9. Interacts with TTI1 and TELO2; when TTI1 and TELO2 are phosphorylated by CK2.
messages: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins and plays a role in several biological processes such as cell cycle, cell proliferation, or maintenance of chromosome stability. Ubiquitinates mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation. In contrast, does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex. As a consequence, mTORC1 is inactivated to restrain cell growth and protein translation, while mTORC2 is the activated due to the relief of feedback inhibition by mTORC1. Plays a role in maintaining epithelial cell survival by regulating the turn-over of chromatin modulator PRMT4 through ubiquitination and degradation by the proteasomal pathway. Regulates also PPARgamma stability by facilitating PPARgamma/PPARG ubiquitination and thereby plays a role in adipocyte differentiation.

9739:TMEM47
gene id: 9739:TMEM47
uniprot id: A0A2U4BZD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

9739:ADAM15
gene id: 9739:ADAM15
uniprot id: A0A6J3RFV5
uniprot id: A0A6J3RG12
uniprot id: A0A6J3RG29
uniprot id: A0A6J3RG39
uniprot id: A0A6J3RG81
uniprot id: A0A6J3RGD7
uniprot id: A0A6J3RGE2
uniprot id: A0A6J3RGE4
uniprot id: A0A6J3RGH1
uniprot id: A0A6J3RGI7
uniprot id: A0A6J3RGT8
uniprot id: A0A6J3RI22
uniprot id: A0A6J3RI26
uniprot id: A0A6J3RI34
uniprot id: A0A6J3RI49
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:AHR
gene id: 9739:AHR
uniprot id: A0A2U4AS58
names: Subcellular Location Annotation
messages: Cytoplasm

9739:TAS2R38
gene id: 9739:TAS2R38
uniprot id: A0A2U4B868
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

9739:RAB3IP
gene id: 9739:RAB3IP
uniprot id: A0A2U3V5P4
uniprot id: A0A2U4CQQ3
uniprot id: A0A2U4CR07
uniprot id: A0A6J3S5F6
names: Similarity
messages: Belongs to the SEC2 family.

9739:SKOR1
gene id: 9739:SKOR1
uniprot id: A0A6J3R1Q2
names: Similarity
messages: Belongs to the SKI family.

9739:TEC
gene id: 9739:TEC
uniprot id: A0A2U4AS28
uniprot id: A0A2U4AS31
uniprot id: A0A2U4AS50
uniprot id: A0A2U4AS55
uniprot id: A0A2U4ASJ4
uniprot id: A0A2U4ASK0
uniprot id: A0A6J3RDL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

9739:ERGIC2
gene id: 9739:ERGIC2
uniprot id: A0A2U3V4E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

9739:SGK2
gene id: 9739:SGK2
uniprot id: A0A6J3PZD9
uniprot id: A0A6J3PZT1
names: Similarity
messages: Belongs to the protein kinase superfamily.

9739:HRH1
gene id: 9739:HRH1
uniprot id: A0A6J3S488
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9739:SELENOM
gene id: 9739:SELENOM
uniprot id: A0A2U4CJQ3
names: Similarity
messages: Belongs to the selenoprotein M/F family.

9739:AMELX
gene id: 9739:AMELX
uniprot id: A0A6J3QSP0
names: Similarity
messages: Belongs to the amelogenin family.

9739:CAB39
gene id: 9739:CAB39
uniprot id: A0A2U4ADJ1
uniprot id: A0A2U4AE35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

9739:LEF1
gene id: 9739:LEF1
uniprot id: A0A2U4AQW4
uniprot id: A0A6J3RD14
uniprot id: A0A6J3RD27
uniprot id: A0A6J3RFE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

9739:LTN1
gene id: 9739:LTN1
uniprot id: A0A6J3RAK9
uniprot id: A0A6J3RAU5
uniprot id: A0A6J3RBB0
uniprot id: A0A6J3RBL0
uniprot id: A0A6J3RDB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LTN1 family.
messages: Component of the ribosome quality control complex (RQC).
messages: E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.
messages: cytosol

9739:CSF2RB
gene id: 9739:CSF2RB
uniprot id: A0A6J3S597
names: Subcellular Location Annotation
messages: Membrane

9739:POLR2J
gene id: 9739:POLR2J
uniprot id: A0A6J3Q4N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft.
messages: Nucleus

9739:SIVA1
gene id: 9739:SIVA1
uniprot id: A0A2U3V608
uniprot id: A0A2U4B8G8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl-x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.
messages: Nucleus

9739:MDM4
gene id: 9739:MDM4
uniprot id: A0A2U4CS15
uniprot id: A0A6J3R132
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain.
messages: Nucleus

9739:SCN1A
gene id: 9739:SCN1A
uniprot id: A0A2U4A9T0
uniprot id: A0A2U4A9T7
uniprot id: A0A2U4A9V7
uniprot id: A0A2U4AA59
uniprot id: A0A2U4AAI3
uniprot id: A0A6J3RMD8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

9739:ACTR1B
gene id: 9739:ACTR1B
uniprot id: A0A2U4B0F6
names: Similarity
messages: Belongs to the actin family.

9739:SEPTIN10
gene id: 9739:SEPTIN10
uniprot id: A0A6J3PW59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

9739:ANKZF1
gene id: 9739:ANKZF1
uniprot id: A0A2U3V4H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKZF1/VMS1 family.
messages: Cytoplasm

9739:LOC109550589
gene id: 9739:LOC109550589
uniprot id: A0A2U4BNR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I LYR family.
messages: Mammalian complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9739:CDC42
gene id: 9739:CDC42
uniprot id: A0A2U4BLM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

9739:SOX2
gene id: 9739:SOX2
uniprot id: A0A2U3UZA2
names: Subcellular Location Annotation
messages: Nucleus

9739:FAM83A
gene id: 9739:FAM83A
uniprot id: A0A6J3Q8T0
uniprot id: A0A6J3Q9K4
names: Similarity
messages: Belongs to the FAM83 family.

9739:LOC101338881
gene id: 9739:LOC101338881
uniprot id: A0A6J3RVQ3
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9739:LOC109547216
gene id: 9739:LOC109547216
uniprot id: A0A6J3RC56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

9739:LOC101333801
gene id: 9739:LOC101333801
uniprot id: A0A2U4BJ83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL18 family.
messages: Rough endoplasmic reticulum

9739:MCEE
gene id: 9739:MCEE
uniprot id: A0A2U4C7T9
uniprot id: A0A6J3R065
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

9739:ZNF287
gene id: 9739:ZNF287
uniprot id: A0A2U4C2W0
names: Subcellular Location Annotation
messages: Nucleus

9739:LOC117309508
gene id: 9739:LOC117309508
uniprot id: A0A6J3QM11
names: Similarity
messages: Belongs to the complex I LYR family.

9739:MRPL11
gene id: 9739:MRPL11
uniprot id: A0A6J3RRN8
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

9739:MPP4
gene id: 9739:MPP4
uniprot id: A0A2U3V892
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane

9739:INHA
gene id: 9739:INHA
uniprot id: A0A2U3V3Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Dimeric, linked by one or more disulfide bonds. Inhibin A is a dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition.
messages: Secreted

9739:ACTA2
gene id: 9739:ACTA2
uniprot id: A0A2U3V5Z6
uniprot id: A0A6J3Q623
names: Similarity
messages: Belongs to the actin family.

9739:LOC101321246
gene id: 9739:LOC101321246
uniprot id: A0A6J3Q684
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

9739:RPS27
gene id: 9739:RPS27
uniprot id: A0A2U4A1R4
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

9739:MAP3K12
gene id: 9739:MAP3K12
uniprot id: A0A6J3S630
uniprot id: A0A6J3S636
uniprot id: A0A6J3S6C2
uniprot id: A0A6J3S6C7
uniprot id: A0A6J3S6K8
uniprot id: A0A6J3S6L1
uniprot id: A0A6J3S7F3
uniprot id: A0A6J3S7G0
uniprot id: A0A6J3S7S4
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: May be an activator of the JNK/SAPK pathway.

9739:NPC1L1
gene id: 9739:NPC1L1
uniprot id: A0A6J3RW31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

9739:LOC117313026
gene id: 9739:LOC117313026
uniprot id: A0A6J3RNU1
uniprot id: A0A6J3RPM2
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

9739:TFRC
gene id: 9739:TFRC
uniprot id: A0A2U4ABP2
uniprot id: A0A2U4ABZ6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Acts as a lipid sensor that regulates mitochondrial fusion by regulating activation of the JNK pathway.
messages: Homodimer; disulfide-linked.
messages: Melanosome
messages: Membrane
messages: Stearoylated.

9739:MRE11
gene id: 9739:MRE11
uniprot id: A0A2U4AEB1
uniprot id: A0A2U4AEC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRE11/RAD32 family.
messages: Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
messages: Nucleus

9739:SLC44A3
gene id: 9739:SLC44A3
uniprot id: A0A2U3V5U5
uniprot id: A0A2U3V5V1
uniprot id: A0A2U4A1J7
uniprot id: A0A2U4A1K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

9739:ENKD1
gene id: 9739:ENKD1
uniprot id: A0A6J3QCF7
uniprot id: A0A6J3QCS7
uniprot id: A0A6J3QCZ6
uniprot id: A0A6J3QD63
names: Subcellular Location Annotation
messages: cilium axoneme

9739:LIAS
gene id: 9739:LIAS
uniprot id: A0A2U3VAH7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Mitochondrion

9739:NPFFR1
gene id: 9739:NPFFR1
uniprot id: A0A2U4BE74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

9739:LOC117308662
gene id: 9739:LOC117308662
uniprot id: A0A6J3Q8R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

9739:LOC101326040
gene id: 9739:LOC101326040
uniprot id: A0A6J3PXZ3
uniprot id: A0A6J3PY24
uniprot id: A0A6J3PY35
uniprot id: A0A6J3PYA4
uniprot id: A0A6J3PYK1
names: Subcellular Location Annotation
messages: Nucleus

9739:ABCB10
gene id: 9739:ABCB10
uniprot id: A0A6J3Q4S5
uniprot id: A0A6J3Q584
uniprot id: A0A6J3Q5J8
names: Subcellular Location Annotation
messages: Membrane

9739:LDHB
gene id: 9739:LDHB
uniprot id: C6L2F1
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

9739:CKS1B
gene id: 9739:CKS1B
uniprot id: A0A6J3RH08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
messages: Forms a homohexamer that can probably bind six kinase subunits.

9739:RPS20
gene id: 9739:RPS20
uniprot id: A0A2U3V0Y5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Component of the 40S small ribosomal subunit.

9739:CXCR1
gene id: 9739:CXCR1
uniprot id: A0A6J3RN69
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9739:CAMK4
gene id: 9739:CAMK4
uniprot id: A0A2U4BT38
uniprot id: A0A6J3R2P7
names: Similarity
messages: Belongs to the protein kinase superfamily.

9739:RPTOR
gene id: 9739:RPTOR
uniprot id: A0A6J3QLF0
uniprot id: A0A6J3QLJ9
uniprot id: A0A6J3QM22
uniprot id: A0A6J3QM45
uniprot id: A0A6J3QMK1
names: Similarity
messages: Belongs to the WD repeat RAPTOR family.

9739:CDC42SE2
gene id: 9739:CDC42SE2
uniprot id: A0A2U4AGA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Interacts with CDC42 (in GTP-bound form). Interacts weakly with RAC1 and not at all with RHOA.
messages: Membrane
messages: Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages.
messages: cytoskeleton

9739:WAS
gene id: 9739:WAS
uniprot id: A0A6J3QTT1
uniprot id: A0A6J3QUE7
names: Subcellular Location Annotation
messages: Nucleus

9739:GPR83
gene id: 9739:GPR83
uniprot id: A0A2U4AEE8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9739:LOC101326122
gene id: 9739:LOC101326122
uniprot id: A0A2U4ABD9
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

9739:RNASE13
gene id: 9739:RNASE13
uniprot id: A0A6J3QZH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

9739:HCFC2
gene id: 9739:HCFC2
uniprot id: A0A2U4CRD2
uniprot id: A0A2U4CRD6
uniprot id: A0A2U4CRE2
uniprot id: A0A2U4CRN9
names: Subcellular Location Annotation
messages: Nucleus

9739:RIPPLY2
gene id: 9739:RIPPLY2
uniprot id: A0A2U4AUM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ripply family.
messages: Nucleus

9739:SYNCRIP
gene id: 9739:SYNCRIP
uniprot id: A0A6J3RPH4
uniprot id: A0A6J3RPU4
uniprot id: A0A6J3S8P7
uniprot id: A0A6J3S8Z4
uniprot id: A0A6J3S9C6
uniprot id: A0A6J3SAB0
names: Subcellular Location Annotation
messages: Cytoplasm

9739:ATOH7
gene id: 9739:ATOH7
uniprot id: A0A2U4BEY0
names: Subcellular Location Annotation
messages: Nucleus
messages: Perikaryon
messages: axon

9739:RPL7A
gene id: 9739:RPL7A
uniprot id: A0A2U4BIM2
uniprot id: A0A2U4BIR7
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

9739:RASGRP2
gene id: 9739:RASGRP2
uniprot id: A0A6J3RQK8
uniprot id: A0A6J3RQL4
names: Similarity
messages: Belongs to the RASGRP family.

9739:NUDT7
gene id: 9739:NUDT7
uniprot id: A0A2U3UYK0
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

9739:NKAIN3
gene id: 9739:NKAIN3
uniprot id: A0A2U4AJ11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

9739:PDCD5
gene id: 9739:PDCD5
uniprot id: A0A2U4BTN3
names: Similarity
messages: Belongs to the PDCD5 family.

9739:NXT2
gene id: 9739:NXT2
uniprot id: A0A2U4CI51
uniprot id: A0A2U4CI54
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

9739:RAD21L1
gene id: 9739:RAD21L1
uniprot id: A0A2U3V2A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

9739:QPCT
gene id: 9739:QPCT
uniprot id: A0A2U4BZ10
uniprot id: A0A2U4BZ20
uniprot id: A0A2U4BZ60
uniprot id: A0A2U4BZ71
names: Similarity
messages: Belongs to the glutaminyl-peptide cyclotransferase family.

9739:DCLRE1C
gene id: 9739:DCLRE1C
uniprot id: A0A2U4B744
uniprot id: A0A2U4B7B0
uniprot id: A0A2U4B7I4
uniprot id: A0A6J3R1L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

9739:CDH9
gene id: 9739:CDH9
uniprot id: A0A2U4CMJ0
uniprot id: A0A6J3RB14
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

9739:LOC101318932
gene id: 9739:LOC101318932
uniprot id: A0A6J3PUV7
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

9739:TMEM192
gene id: 9739:TMEM192
uniprot id: A0A2U4AMS0
uniprot id: A0A2U4AMS2
uniprot id: A0A2U4AMS5
uniprot id: A0A2U4AMS8
uniprot id: A0A2U4AMS9
uniprot id: A0A2U4AMT5
uniprot id: A0A2U4AMV3
uniprot id: A0A2U4AMW3
uniprot id: A0A2U4AN64
uniprot id: A0A2U4AN68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM192 family.
messages: Late endosome
messages: Lysosome membrane
messages: Membrane

9739:TBX3
gene id: 9739:TBX3
uniprot id: A0A6J3PS95
uniprot id: A0A6J3PSV0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9739:SLC25A28
gene id: 9739:SLC25A28
uniprot id: A0A2U3V100
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9739:LOC101333410
gene id: 9739:LOC101333410
uniprot id: A0A6J3QU72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase VIIb family.
messages: Membrane
messages: Mitochondrion inner membrane

9739:SLC5A12
gene id: 9739:SLC5A12
uniprot id: A0A6J3RSF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

9739:LOC117308951
gene id: 9739:LOC117308951
uniprot id: A0A2U3V7P0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

9739:LOC117312761
gene id: 9739:LOC117312761
uniprot id: A0A6J3RL91
names: Similarity
messages: Belongs to the NUT family.

9739:DCTN4
gene id: 9739:DCTN4
uniprot id: A0A6J3R3S1
uniprot id: A0A6J3R471
uniprot id: A0A6J3R5Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunit 4 family.
messages: cell cortex
messages: centrosome
messages: sarcomere
messages: stress fiber

9739:LOC101324296
gene id: 9739:LOC101324296
uniprot id: A0A2U4CD89
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

9739:LOC117308488
gene id: 9739:LOC117308488
uniprot id: A0A6J3RE60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.
messages: Catalyzes viral DNA integration into the host chromosome, by performing a series of DNA cutting and joining reactions. This enzyme activity takes place after virion entry into a cell and reverse transcription of the RNA genome in dsDNA. The first step in the integration process is 3' processing. This step requires a complex comprising the viral genome, matrix protein and integrase. This complex is called the pre-integration complex (PIC). The integrase protein removes 2 nucleotides from each 3' end of the viral DNA, leaving recessed CA OH's at the 3' ends. In the second step that requires cell division, the PIC enters cell nucleus. In the third step, termed strand transfer, the integrase protein joins the previously processed 3' ends to the 5' ends of strands of target cellular DNA at the site of integration. The last step is viral DNA integration into host chromosome.
messages: Forms the spherical core of the virion that encapsulates the genomic RNA-nucleocapsid complex.
messages: Virion

9739:TXNIP
gene id: 9739:TXNIP
uniprot id: A0A2U3V3M9
names: Similarity
messages: Belongs to the arrestin family.

9739:CCR4
gene id: 9739:CCR4
uniprot id: A0A2U4CAT7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9739:PLXNA1
gene id: 9739:PLXNA1
uniprot id: A0A6J3S3F9
uniprot id: A0A6J3S4N6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:LLGL2
gene id: 9739:LLGL2
uniprot id: A0A6J3QLK2
uniprot id: A0A6J3QLQ0
uniprot id: A0A6J3QM75
uniprot id: A0A6J3QM98
uniprot id: A0A6J3QMA4
uniprot id: A0A6J3QMQ3
uniprot id: A0A6J3QMQ8
names: Similarity
messages: Belongs to the WD repeat L(2)GL family.

9739:LOC101316507
gene id: 9739:LOC101316507
uniprot id: A0A2U3V6W5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9739:UBALD2
gene id: 9739:UBALD2
uniprot id: A0A6J3QK10
uniprot id: A0A6J3QKJ1
names: Similarity
messages: Belongs to the UBALD family.

9739:SLC25A36
gene id: 9739:SLC25A36
uniprot id: A0A6J3R8R0
uniprot id: A0A6J3R9U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9739:LOC117308675
gene id: 9739:LOC117308675
uniprot id: A0A6J3Q9C1
names: Similarity
messages: Belongs to the AP-2 family.

9739:DHTKD1
gene id: 9739:DHTKD1
uniprot id: A0A6J3R0G2
uniprot id: A0A6J3R0S7
uniprot id: A0A6J3R1A2
uniprot id: A0A6J3R2K4
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

9739:FAM114A1
gene id: 9739:FAM114A1
uniprot id: A0A6J3RE20
uniprot id: A0A6J3RFT0
names: Similarity
messages: Belongs to the FAM114 family.

9739:TMEM150A
gene id: 9739:TMEM150A
uniprot id: A0A2U4BX10
uniprot id: A0A2U4BX12
uniprot id: A0A6J3PX74
names: Subcellular Location Annotation
messages: Membrane

9739:LOC109547314
gene id: 9739:LOC109547314
uniprot id: A0A6J3Q3X5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.

9739:LMX1A
gene id: 9739:LMX1A
uniprot id: A0A2U4B986
names: Subcellular Location Annotation
messages: Nucleus

9739:LOC101328357
gene id: 9739:LOC101328357
uniprot id: A0A2U4AFY0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9739:CA5B
gene id: 9739:CA5B
uniprot id: A0A6J3QSS0
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

9739:TRPT1
gene id: 9739:TRPT1
uniprot id: A0A2U4BWL7
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.

9739:MXRA8
gene id: 9739:MXRA8
uniprot id: A0A6J3QGC7
uniprot id: A0A6J3QGX9
uniprot id: A0A6J3QHG6
uniprot id: A0A6J3QHH8
uniprot id: A0A6J3QHI7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9739:PRPS1
gene id: 9739:PRPS1
uniprot id: A0A2U3V999
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family.
messages: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
messages: Homodimer. The active form is probably a hexamer composed of 3 homodimers.

9739:TUBB
gene id: 9739:TUBB
uniprot id: A0A2U3V2D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

9739:PDE6C
gene id: 9739:PDE6C
uniprot id: A0A6J3Q4R5
uniprot id: A0A6J3Q4R6
uniprot id: A0A6J3Q4Z0
uniprot id: A0A6J3Q5I1
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9739:CA5A
gene id: 9739:CA5A
uniprot id: A0A6J3QG86
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

9739:ASPM
gene id: 9739:ASPM
uniprot id: A0A6J3QU92
uniprot id: A0A6J3QV45
uniprot id: A0A6J3QV62
uniprot id: A0A6J3QVB6
uniprot id: A0A6J3QVG3
uniprot id: A0A6J3QVG7
names: Subcellular Location Annotation
messages: Nucleus

9739:UNKL
gene id: 9739:UNKL
uniprot id: A0A6J3PZU6
uniprot id: A0A6J3PZV1
uniprot id: A0A6J3PZV4
uniprot id: A0A6J3PZV9
uniprot id: A0A6J3PZZ8
uniprot id: A0A6J3Q027
uniprot id: A0A6J3Q0H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unkempt family.
messages: Cytoplasm

9739:SLC5A3
gene id: 9739:SLC5A3
uniprot id: A0A2U4ABL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

9739:UBE2G1
gene id: 9739:UBE2G1
uniprot id: A0A2U4AN77
uniprot id: A0A2U4ANA6
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9739:INPP1
gene id: 9739:INPP1
uniprot id: A0A6J3RM00
uniprot id: A0A6J3RNL4
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

9739:HDX
gene id: 9739:HDX
uniprot id: A0A2U4B395
names: Subcellular Location Annotation
messages: Nucleus

9739:METTL1
gene id: 9739:METTL1
uniprot id: A0A2U4CRL5
uniprot id: A0A2U4CRM3
uniprot id: A0A2U4CRY8
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Forms a complex with WDR4.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Phosphorylation at Ser-54 inactivates its catalytic activity but does not affect the interaction with WDR4.

9739:SORCS2
gene id: 9739:SORCS2
uniprot id: A0A6J3RFF7
names: Similarity
messages: Belongs to the VPS10-related sortilin family. SORCS subfamily.

9739:HBEGF
gene id: 9739:HBEGF
uniprot id: A0A6J3R5B0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:GABRA1
gene id: 9739:GABRA1
uniprot id: A0A2U3UYL9
uniprot id: A0A2U3UYM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA1 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9739:PPP1R13B
gene id: 9739:PPP1R13B
uniprot id: A0A6J3QVB5
uniprot id: A0A6J3QVP9
uniprot id: A0A6J3QVV8
uniprot id: A0A6J3QWA7
names: Subcellular Location Annotation
messages: Nucleus

9739:LOC101324432
gene id: 9739:LOC101324432
uniprot id: A0A2U4C5P4
uniprot id: A0A6J3RYH4
names: Similarity
messages: Belongs to the serpin family.

9739:PGR
gene id: 9739:PGR
uniprot id: A0A2U4AE72
uniprot id: A0A2U4AE79
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Cytoplasm
messages: Nucleus
messages: Steroid hormone receptor involved in the regulation of eukaryotic gene expression which affects cellular proliferation and differentiation in target tissues.

9739:LOC101331895
gene id: 9739:LOC101331895
uniprot id: A0A2U4CFK1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

9739:LOC109550195
gene id: 9739:LOC109550195
uniprot id: A0A2U4BFI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. As part of the U7 snRNP it is involved in histone 3'-end processing.
messages: cytosol

9739:ANK2
gene id: 9739:ANK2
uniprot id: A0A6J3RCV9
uniprot id: A0A6J3RCW3
uniprot id: A0A6J3RCY4
uniprot id: A0A6J3RCY9
uniprot id: A0A6J3RDI5
uniprot id: A0A6J3RDJ1
uniprot id: A0A6J3RDR2
uniprot id: A0A6J3RFA3
uniprot id: A0A6J3RFA7
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

9739:TET1
gene id: 9739:TET1
uniprot id: A0A6J3Q6L7
uniprot id: A0A6J3Q6M5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TET family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Chromosome
messages: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development.
messages: The zinc ions have a structural role.

9739:YIF1B
gene id: 9739:YIF1B
uniprot id: A0A6J3QE13
uniprot id: A0A6J3QE16
uniprot id: A0A6J3QE23
uniprot id: A0A6J3QE28
uniprot id: A0A6J3QEI9
uniprot id: A0A6J3QEJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIF1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Has a role in transport between endoplasmic reticulum and Golgi.
messages: Membrane

9739:MOCOS
gene id: 9739:MOCOS
uniprot id: A0A2U4AYA3
uniprot id: A0A2U4AYA4
uniprot id: A0A2U4AYA6
uniprot id: A0A2U4AYA8
uniprot id: A0A2U4AYA9
uniprot id: A0A2U4AYB1
uniprot id: A0A2U4AYB6
uniprot id: A0A2U4AYD9
uniprot id: A0A2U4AYR1
uniprot id: A0A6J3PTW0
uniprot id: A0A6J3PU97
uniprot id: A0A6J3PUB5
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.
messages: Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.

9739:TLR3
gene id: 9739:TLR3
uniprot id: A0A2U4A859
uniprot id: A0A2U4A8B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

9739:CLCN6
gene id: 9739:CLCN6
uniprot id: A0A2U3UZ85
uniprot id: A0A2U4AZM9
uniprot id: A0A2U4AZN7
uniprot id: A0A2U4B026
uniprot id: A0A2U4B031
uniprot id: A0A6J3Q9K8
uniprot id: A0A6J3QA15
uniprot id: A0A6J3QAC4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:SOHLH2
gene id: 9739:SOHLH2
uniprot id: A0A6J3QBF9
uniprot id: A0A6J3QBL8
names: Subcellular Location Annotation
messages: Nucleus

9739:PLCG1
gene id: 9739:PLCG1
uniprot id: A0A6J3Q3M1
uniprot id: A0A6J3Q3P9
uniprot id: A0A6J3Q4D3
names: Function
messages: Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.

9739:FAM8A1
gene id: 9739:FAM8A1
uniprot id: A0A2U3V0U7
uniprot id: A0A2U4C5K8
names: Subcellular Location Annotation
messages: Membrane

9739:LOC109549034
gene id: 9739:LOC109549034
uniprot id: A0A6J3R851
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

9739:SUFU
gene id: 9739:SUFU
uniprot id: A0A2U4BQG9
uniprot id: A0A2U4BQN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUFU family.
messages: Cytoplasm
messages: Negative regulator in the hedgehog signaling pathway. Down-regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of GLI3 (GLI3FL). GLI3FL is complexed with SUFU in the cytoplasm and is maintained in a neutral state. Without the Hh signal, the SUFU-GLI3 complex is recruited to cilia, leading to the efficient processing of GLI3FL into GLI3R. When Hh signaling is initiated, SUFU dissociates from GLI3FL and the latter translocates to the nucleus, where it is phosphorylated, destabilized, and converted to a transcriptional activator (GLI3A).
messages: Nucleus

9739:GLOD4
gene id: 9739:GLOD4
uniprot id: A0A2U4ANJ8
names: Similarity
messages: Belongs to the glyoxalase I family.

9739:AP1G1
gene id: 9739:AP1G1
uniprot id: A0A2U4BD22
uniprot id: A0A2U4BD41
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

9739:TSPAN6
gene id: 9739:TSPAN6
uniprot id: A0A2U3V6S1
uniprot id: A0A2U4B3L4
uniprot id: A0A2U4B3Q3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:PTEN
gene id: 9739:PTEN
uniprot id: A0A2U4BLD8
uniprot id: A0A2U4BLH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3,4,5)P3 > PtdIns(3,4)P2 > PtdIns3P > Ins(1,3,4,5)P4.
messages: Belongs to the PTEN phosphatase protein family.
messages: Cytoplasm
messages: Nucleus
messages: PML body
messages: Postsynaptic density
messages: dendritic spine

9739:PTPN4
gene id: 9739:PTPN4
uniprot id: A0A2U4B3T0
uniprot id: A0A2U4B3U7
uniprot id: A0A2U4B3Y6
uniprot id: A0A2U4B482
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: May act at junctions between the membrane and the cytoskeleton.
messages: cytoskeleton

9739:PLBD1
gene id: 9739:PLBD1
uniprot id: A0A2U4BI92
uniprot id: A0A2U4BIM9
names: Function
names: Similarity
messages: Belongs to the phospholipase B-like family.
messages: Putative phospholipase.

9739:CEBPA
gene id: 9739:CEBPA
uniprot id: A0A2U4BTV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. C/EBP subfamily.
messages: Nucleus

9739:KIFC3
gene id: 9739:KIFC3
uniprot id: A0A6J3QFE9
uniprot id: A0A6J3QFF4
uniprot id: A0A6J3QFF7
uniprot id: A0A6J3QFG1
uniprot id: A0A6J3QG17
uniprot id: A0A6J3QG22
uniprot id: A0A6J3QG35
uniprot id: A0A6J3QG44
uniprot id: A0A6J3QGK3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9739:SCAND1
gene id: 9739:SCAND1
uniprot id: A0A2U4CLV9
names: Subcellular Location Annotation
messages: Nucleus

9739:UBE3B
gene id: 9739:UBE3B
uniprot id: A0A2U4CKR6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:DKK2
gene id: 9739:DKK2
uniprot id: A0A2U4AQU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

9739:SLC25A14
gene id: 9739:SLC25A14
uniprot id: A0A6J3QSE2
uniprot id: A0A6J3QTE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9739:ZSCAN22
gene id: 9739:ZSCAN22
uniprot id: A0A2U4AU98
names: Subcellular Location Annotation
messages: Nucleus

9739:TM6SF1
gene id: 9739:TM6SF1
uniprot id: A0A2U4C7L9
uniprot id: A0A6J3R0U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TM6SF family.
messages: Membrane

9739:OXCT2
gene id: 9739:OXCT2
uniprot id: A0A6J3QJI2
names: Function
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.

9739:LOC101319508
gene id: 9739:LOC101319508
uniprot id: A0A2U4C4T7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9739:LOC101330241
gene id: 9739:LOC101330241
uniprot id: A0A2U3V5G5
uniprot id: A0A2U3V732
uniprot id: A0A2U4CJP4
uniprot id: A0A2U4CJP7
uniprot id: A0A2U4CJQ0
uniprot id: A0A2U4CJQ1
uniprot id: A0A2U4CJX5
uniprot id: A0A6J3PT23
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
messages: E3 ubiquitin-protein ligase.
messages: Endoplasmic reticulum membrane
messages: Mitochondrion membrane
messages: The RING-type zinc finger domain is responsible for E3 ligase activity.

9739:NGB
gene id: 9739:NGB
uniprot id: A0A6J3QWY0
names: Similarity
messages: Belongs to the globin family.

9739:TAFA3
gene id: 9739:TAFA3
uniprot id: A0A6J3RTI9
uniprot id: A0A6J3RTL8
uniprot id: A0A6J3RTW9
names: Similarity
messages: Belongs to the TAFA family.

9739:UTP3
gene id: 9739:UTP3
uniprot id: A0A2U3V9A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAS10 family.
messages: nucleolus

9739:SLC4A5
gene id: 9739:SLC4A5
uniprot id: A0A6J3PW78
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane

9739:WDR18
gene id: 9739:WDR18
uniprot id: A0A6J3R7W6
uniprot id: A0A6J3R8V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat IPI3/WDR18 family.
messages: Component of the 5FMC complex, at least composed of PELP1, LAS1L, TEX10, WDR18 and SENP3; the complex interacts with methylated CHTOP and ZNF148. Interacts with NOL9. Component of the PELP1 complex, composed of at least PELP1, TEX10 and WDR18. The complex interacts with pre-60S ribosome particles.
messages: Cytoplasm
messages: Dynein axonemal particle
messages: Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes. Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit. May play a role during development.
messages: nucleolus
messages: nucleoplasm

9739:LOC101330616
gene id: 9739:LOC101330616
uniprot id: A0A2U4BBY3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9739:SLC29A4
gene id: 9739:SLC29A4
uniprot id: A0A6J3Q0N6
uniprot id: A0A6J3Q0Q4
uniprot id: A0A6J3Q0R5
uniprot id: A0A6J3Q0S0
uniprot id: A0A6J3Q0Y8
uniprot id: A0A6J3Q1B2
uniprot id: A0A6J3Q1B8
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

9739:TMEM255B
gene id: 9739:TMEM255B
uniprot id: A0A6J3QBL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM255 family.
messages: Membrane

9739:UBE2A
gene id: 9739:UBE2A
uniprot id: A0A2U3VA31
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9739:SELENOT
gene id: 9739:SELENOT
uniprot id: A0A2U4B9M2
names: Similarity
messages: Belongs to the SelWTH family. Selenoprotein T subfamily.

9739:LOC101320643
gene id: 9739:LOC101320643
uniprot id: A0A2U3V4N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

9739:STX11
gene id: 9739:STX11
uniprot id: A0A2U4CPT3
names: Similarity
messages: Belongs to the syntaxin family.

9739:MBOAT2
gene id: 9739:MBOAT2
uniprot id: A0A2U4C0D0
names: Subcellular Location Annotation
messages: Membrane

9739:KCNJ10
gene id: 9739:KCNJ10
uniprot id: A0A6J3RCB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

9739:PPP4R3A
gene id: 9739:PPP4R3A
uniprot id: A0A2U4A0Q0
uniprot id: A0A2U4A0R6
uniprot id: A0A2U4A1N1
names: Similarity
messages: Belongs to the SMEK family.

9739:PIGX
gene id: 9739:PIGX
uniprot id: A0A2U4A9P9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGX family.
messages: Endoplasmic reticulum membrane
messages: Essential component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis.

9739:KIF18A
gene id: 9739:KIF18A
uniprot id: A0A2U4CF40
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9739:ELOVL5
gene id: 9739:ELOVL5
uniprot id: A0A2U4CIQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL5 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: dendrite

9739:STAC2
gene id: 9739:STAC2
uniprot id: A0A6J3QMB1
names: Subcellular Location Annotation
messages: sarcolemma

9739:LOC101336401
gene id: 9739:LOC101336401
uniprot id: A0A2U4B3I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM256 family.
messages: Membrane

9739:JPT1
gene id: 9739:JPT1
uniprot id: A0A2U3V0H9
uniprot id: A0A2U4BM69
uniprot id: A0A2U4BM76
uniprot id: A0A2U4BMB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

9739:SP4
gene id: 9739:SP4
uniprot id: A0A2U4ASN3
uniprot id: A0A6J3RWD0
names: Subcellular Location Annotation
messages: Nucleus

9739:XKR7
gene id: 9739:XKR7
uniprot id: A0A2U4CL87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

9739:RPS21
gene id: 9739:RPS21
uniprot id: A0A2U4C2D3
uniprot id: A0A6J3Q4H6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS21 family.
messages: Component of the 40S small ribosomal subunit.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum
messages: cytosol

9739:MASP1
gene id: 9739:MASP1
uniprot id: A0A2U4C820
uniprot id: A0A2U4C825
uniprot id: A0A2U4C832
uniprot id: A0A2U4C8B1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9739:IL24
gene id: 9739:IL24
uniprot id: A0A6J3R1G1
uniprot id: A0A6J3R286
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

9739:ESD
gene id: 9739:ESD
uniprot id: A0A2U4BFY3
uniprot id: A0A2U4BFZ7
uniprot id: A0A2U4BG12
uniprot id: A0A6J3QB89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the esterase D family.
messages: Cytoplasmic vesicle
messages: Serine hydrolase involved in the detoxification of formaldehyde.

9739:DIMT1
gene id: 9739:DIMT1
uniprot id: A0A2U3V9B3
uniprot id: A0A2U3V9C9
uniprot id: A0A6J3R2H9
uniprot id: A0A6J3R467
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:NLGN3
gene id: 9739:NLGN3
uniprot id: A0A6J3QS73
uniprot id: A0A6J3QSS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

9739:DCTN1
gene id: 9739:DCTN1
uniprot id: A0A6J3PVC5
uniprot id: A0A6J3PVC6
uniprot id: A0A6J3PVL6
uniprot id: A0A6J3PVM1
uniprot id: A0A6J3PVM2
uniprot id: A0A6J3PW18
uniprot id: A0A6J3PW23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin 150 kDa subunit family.
messages: cell cortex
messages: cytoskeleton

9739:HCFC1
gene id: 9739:HCFC1
uniprot id: A0A6J3QR63
uniprot id: A0A6J3QR67
uniprot id: A0A6J3QRE9
uniprot id: A0A6J3QRF5
uniprot id: A0A6J3QRY1
uniprot id: A0A6J3QRY8
uniprot id: A0A6J3QRY9
uniprot id: A0A6J3QSJ3
uniprot id: A0A6J3QSJ7
names: Subcellular Location Annotation
messages: Nucleus

9739:SENP1
gene id: 9739:SENP1
uniprot id: A0A2U4BA56
uniprot id: A0A2U4BA88
uniprot id: A0A2U4BAJ3
uniprot id: A0A6J3S7C4
names: Similarity
messages: Belongs to the peptidase C48 family.

9739:LOC101338897
gene id: 9739:LOC101338897
uniprot id: A0A2U4A876
names: Similarity
messages: Belongs to the cytochrome P450 family.

9739:NEK7
gene id: 9739:NEK7
uniprot id: A0A2U4A4T5
uniprot id: A0A2U4A4U8
uniprot id: A0A6J3QQY0
uniprot id: A0A6J3QR80
uniprot id: A0A6J3QRB6
uniprot id: A0A6J3QRR6
uniprot id: A0A6J3QRW6
uniprot id: A0A6J3QS82
names: Similarity
messages: Belongs to the protein kinase superfamily.

9739:EXTL2
gene id: 9739:EXTL2
uniprot id: A0A2U3V029
uniprot id: A0A2U4A292
uniprot id: A0A2U4A293
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:LOC101325015
gene id: 9739:LOC101325015
uniprot id: A0A2U3V5J3
uniprot id: A0A2U3V5J7
uniprot id: A0A6J3Q6P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

9739:PRMT3
gene id: 9739:PRMT3
uniprot id: A0A2U3V2U1
uniprot id: A0A2U4CES2
uniprot id: A0A2U4CES5
uniprot id: A0A2U4CES6
uniprot id: A0A2U4CES7
uniprot id: A0A2U4CET0
uniprot id: A0A6J3RVG9
names: Subcellular Location Annotation
messages: Cytoplasm

9739:IRF2
gene id: 9739:IRF2
uniprot id: A0A2U4A8C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Nucleus

9739:ITGAM
gene id: 9739:ITGAM
uniprot id: A0A6J3Q0B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9739:LOC117309526
gene id: 9739:LOC117309526
uniprot id: A0A6J3QMQ2
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

9739:TSSK1B
gene id: 9739:TSSK1B
uniprot id: A0A6J3PT10
names: Similarity
messages: Belongs to the protein kinase superfamily.

9739:ELOC
gene id: 9739:ELOC
uniprot id: A0A6J3Q826
names: Similarity
messages: Belongs to the SKP1 family.

9739:PHOX2B
gene id: 9739:PHOX2B
uniprot id: A0A2U4ARL5
names: Subcellular Location Annotation
messages: Nucleus

9739:LCN15
gene id: 9739:LCN15
uniprot id: A0A6J3RLK3
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

9739:SUPT6H
gene id: 9739:SUPT6H
uniprot id: A0A6J3QJQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT6 family.
messages: Nucleus
messages: Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII).

9739:TNFSF9
gene id: 9739:TNFSF9
uniprot id: A0A6J3R749
names: Similarity
messages: Belongs to the tumor necrosis factor family.

9739:PELI2
gene id: 9739:PELI2
uniprot id: A0A2U4AEI4
names: Function
names: Similarity
messages: Belongs to the pellino family.
messages: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.

9739:BDKRB2
gene id: 9739:BDKRB2
uniprot id: A0A6J3QWL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Forms a complex with PECAM1 and GNAQ. Interacts with PECAM1.
messages: Membrane
messages: Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.

9739:NOTUM
gene id: 9739:NOTUM
uniprot id: A0A6J3QNB7
names: Similarity
messages: Belongs to the pectinacetylesterase family. Notum subfamily.

9739:YKT6
gene id: 9739:YKT6
uniprot id: A0A6J3RW39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.

9739:TMEM177
gene id: 9739:TMEM177
uniprot id: A0A6J3RNI9
names: Function
names: Similarity
messages: Belongs to the TMEM177 family.
messages: Plays a role in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation and is required for the stabilization of COX20 and the newly synthesized MT-CO2/COX2 protein.

9739:FARS2
gene id: 9739:FARS2
uniprot id: A0A6J3RYJ3
uniprot id: A0A6J3RYM8
uniprot id: A0A6J3RYP2
uniprot id: A0A6J3RYU2
uniprot id: A0A6J3RZI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Mitochondrion matrix

9739:AURKAIP1
gene id: 9739:AURKAIP1
uniprot id: A0A6J3QG31
uniprot id: A0A6J3QGM4
names: Similarity
messages: Belongs to the mitochondrion-specific ribosomal protein mS38 family.

9739:CEP76
gene id: 9739:CEP76
uniprot id: A0A2U3V4J2
uniprot id: A0A2U4A5Q6
uniprot id: A0A6J3PTA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP76 family.
messages: Centrosomal protein involved in regulation of centriole duplication. Required to limit centriole duplication to once per cell cycle by preventing centriole reduplication.
messages: centriole

9739:SULT1C4
gene id: 9739:SULT1C4
uniprot id: A0A2U4B188
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9739:PDE7A
gene id: 9739:PDE7A
uniprot id: A0A2U4AIK7
uniprot id: A0A2U4AIK9
uniprot id: A0A2U4AJ37
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9739:UGP2
gene id: 9739:UGP2
uniprot id: A0A2U3V0R8
uniprot id: A0A2U4BYE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDPGP type 1 family.
messages: Homooctamer.
messages: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.

9739:PSD3
gene id: 9739:PSD3
uniprot id: A0A2U4A7Y8
uniprot id: A0A6J3QR34
uniprot id: A0A6J3QRJ1
names: Subcellular Location Annotation
messages: Membrane
messages: ruffle membrane

9739:MMP28
gene id: 9739:MMP28
uniprot id: A0A2U4C6I1
uniprot id: A0A2U4C6I2
uniprot id: A0A2U4C6K1
uniprot id: A0A2U4C6S6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.
messages: Cytoplasm
messages: Melanosome

9739:ST6GAL1
gene id: 9739:ST6GAL1
uniprot id: A0A2U4C8J4
uniprot id: A0A2U4C8J8
uniprot id: A0A2U4C8K9
uniprot id: A0A6J3R9G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9739:SFRP5
gene id: 9739:SFRP5
uniprot id: A0A6J3Q650
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:ZC3H12D
gene id: 9739:ZC3H12D
uniprot id: A0A2U4CPR6
names: Similarity
messages: Belongs to the ZC3H12 family.

9739:KHSRP
gene id: 9739:KHSRP
uniprot id: A0A6J3R9E5
names: Subcellular Location Annotation
messages: Nucleus

9739:DBP
gene id: 9739:DBP
uniprot id: A0A6J3QE77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

9739:PRKAA2
gene id: 9739:PRKAA2
uniprot id: A0A2U3V6N5
uniprot id: A0A2U4BXM6
uniprot id: A0A2U4BXN6
uniprot id: A0A6J3S507
uniprot id: A0A6J3S5W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: Cytoplasm
messages: Nucleus

9739:ADGRA2
gene id: 9739:ADGRA2
uniprot id: A0A6J3QQC0
uniprot id: A0A6J3QQG1
uniprot id: A0A6J3QR44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

9739:HSPA13
gene id: 9739:HSPA13
uniprot id: A0A2U4ACL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 70 family.
messages: Binds UBQLN2.
messages: Endoplasmic reticulum
messages: Has peptide-independent ATPase activity.
messages: Microsome

9739:CMTM5
gene id: 9739:CMTM5
uniprot id: A0A6J3QTK7
names: Subcellular Location Annotation
messages: Membrane

9739:MGME1
gene id: 9739:MGME1
uniprot id: A0A2U4AQ49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGME1 family.
messages: Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA-primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair.
messages: Mitochondrion

9739:PYGB
gene id: 9739:PYGB
uniprot id: A0A6J3Q2M8
uniprot id: A0A6J3Q367
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

9739:AKR1D1
gene id: 9739:AKR1D1
uniprot id: A0A2U3V7A0
uniprot id: A0A2U3V7A2
uniprot id: A0A2U4CIK4
uniprot id: A0A6J3RXB3
uniprot id: A0A6J3RXB7
uniprot id: A0A6J3RXC3
uniprot id: A0A6J3RXG7
uniprot id: A0A6J3RXH9
uniprot id: A0A6J3RXI4
uniprot id: A0A6J3RY54
names: Similarity
messages: Belongs to the aldo/keto reductase family.

9739:PGK1
gene id: 9739:PGK1
uniprot id: A0A2U3V9F2
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

9739:LOC101330180
gene id: 9739:LOC101330180
uniprot id: A0A2U3V9D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

9739:LAMC3
gene id: 9739:LAMC3
uniprot id: A0A6J3RJI3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

9739:RORA
gene id: 9739:RORA
uniprot id: A0A2U4CCG6
uniprot id: A0A2U4CCH3
uniprot id: A0A2U4CCH7
uniprot id: A0A2U4CCJ7
uniprot id: A0A2U4CCL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

9739:PKIG
gene id: 9739:PKIG
uniprot id: A0A2U4C214
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

9739:RTBDN
gene id: 9739:RTBDN
uniprot id: A0A6J3R8G1
names: Similarity
messages: Belongs to the folate receptor family.

9739:COL4A5
gene id: 9739:COL4A5
uniprot id: A0A2U4CI37
uniprot id: A0A2U4CI38
uniprot id: A0A6J3QTF6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

9739:HHATL
gene id: 9739:HHATL
uniprot id: A0A6J3S0Z9
names: Subcellular Location Annotation
messages: Membrane

9739:FLT1
gene id: 9739:FLT1
uniprot id: A0A2U4BGM2
uniprot id: A0A6J3QAF3
uniprot id: A0A6J3QAU5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Forms a complex composed of PDGFRL, TNK2 and GRB2.
messages: Membrane

9739:UCHL3
gene id: 9739:UCHL3
uniprot id: A0A2U3V1L6
uniprot id: A0A2U4A6S4
uniprot id: A0A2U4A7F6
names: Similarity
messages: Belongs to the peptidase C12 family.

9739:ZGPAT
gene id: 9739:ZGPAT
uniprot id: A0A6J3Q1S6
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with CHD4/Mi-2; the interaction is direct.
messages: Nucleus

9739:C1QBP
gene id: 9739:C1QBP
uniprot id: A0A2U3V3T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAM33 family.
messages: Cell membrane

9739:PIAS1
gene id: 9739:PIAS1
uniprot id: A0A2U4CG40
uniprot id: A0A2U4CG54
names: Similarity
messages: Belongs to the PIAS family.

9739:PTK2
gene id: 9739:PTK2
uniprot id: A0A2U4B2T9
uniprot id: A0A6J3Q9F5
uniprot id: A0A6J3Q9G0
uniprot id: A0A6J3Q9G5
uniprot id: A0A6J3Q9K0
uniprot id: A0A6J3QA74
uniprot id: A0A6J3QA79
uniprot id: A0A6J3QA82
uniprot id: A0A6J3QAB1
uniprot id: A0A6J3QAB7
names: Subcellular Location Annotation
messages: Cell membrane
messages: cell cortex
messages: focal adhesion

9739:FAM110B
gene id: 9739:FAM110B
uniprot id: A0A2U4AIP7
names: Similarity
messages: Belongs to the FAM110 family.

9739:CARMIL1
gene id: 9739:CARMIL1
uniprot id: A0A2U4C5D4
uniprot id: A0A2U4C5D5
uniprot id: A0A2U4C5E1
uniprot id: A0A2U4C5F4
uniprot id: A0A2U4C5F5
uniprot id: A0A2U4C5L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CARMIL family.
messages: Cytoplasm

9739:FAM118B
gene id: 9739:FAM118B
uniprot id: A0A2U4BVI8
uniprot id: A0A2U4BVI9
uniprot id: A0A2U4BVR1
names: Similarity
messages: Belongs to the FAM118 family.

9739:AP3S1
gene id: 9739:AP3S1
uniprot id: A0A2U4BTE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

9739:TRIAP1
gene id: 9739:TRIAP1
uniprot id: A0A2U3V551
names: Similarity
messages: Belongs to the TRIAP1/MDM35 family.

9739:LOC101337471
gene id: 9739:LOC101337471
uniprot id: A0A2U3UZV6
names: Similarity
messages: Belongs to the KHDC1 family.

9739:FOXD1
gene id: 9739:FOXD1
uniprot id: A0A2U4AVE9
names: Subcellular Location Annotation
messages: Nucleus

9739:SERPING1
gene id: 9739:SERPING1
uniprot id: A0A6J3RPY1
uniprot id: A0A6J3RQL6
names: Similarity
messages: Belongs to the serpin family.

9739:CCNP
gene id: 9739:CCNP
uniprot id: A0A6J3QEP8
uniprot id: A0A6J3QF48
names: Similarity
messages: Belongs to the cyclin family.

9739:GADD45G
gene id: 9739:GADD45G
uniprot id: A0A2U3V3E5
names: Similarity
messages: Belongs to the GADD45 family.

9739:AURKA
gene id: 9739:AURKA
uniprot id: A0A2U3V4Z5
uniprot id: A0A2U3V5C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
messages: centrosome

9739:ACOX2
gene id: 9739:ACOX2
uniprot id: A0A6J3S2E2
uniprot id: A0A6J3S2J6
uniprot id: A0A6J3S2K1
uniprot id: A0A6J3S2N0
uniprot id: A0A6J3S383
uniprot id: A0A6J3S3K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

9739:HK2
gene id: 9739:HK2
uniprot id: A0A6J3PV96
uniprot id: A0A6J3PVJ6
uniprot id: A0A6J3PVJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hexokinase family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: cytosol

9739:ATL3
gene id: 9739:ATL3
uniprot id: A0A2U4B4N5
uniprot id: A0A2U4B4P3
uniprot id: A0A6J3RQB3
uniprot id: A0A6J3RQZ2
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

9739:HMOX1
gene id: 9739:HMOX1
uniprot id: A0A2U3V1X9
names: Similarity
messages: Belongs to the heme oxygenase family.

9739:TAF4
gene id: 9739:TAF4
uniprot id: A0A6J3Q226
uniprot id: A0A6J3Q2A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Nucleus

9739:SCN1B
gene id: 9739:SCN1B
uniprot id: A0A6J3QEQ0
uniprot id: A0A6J3QER2
names: Subcellular Location Annotation
messages: Membrane

9739:LOC101339956
gene id: 9739:LOC101339956
uniprot id: A0A2U4BG10
uniprot id: A0A2U4BG52
uniprot id: A0A2U4BGF7
names: Subcellular Location Annotation
messages: Chromosome

9739:OAZ2
gene id: 9739:OAZ2
uniprot id: A0A2U3UYP8
names: Similarity
messages: Belongs to the ODC antizyme family.

9739:TARS2
gene id: 9739:TARS2
uniprot id: A0A2U4A335
uniprot id: A0A2U4A336
uniprot id: A0A2U4A338
uniprot id: A0A2U4A346
uniprot id: A0A2U4A347
uniprot id: A0A2U4A3W0
uniprot id: A0A2U4A3W6
uniprot id: A0A6J3RNU4
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

9739:UBN2
gene id: 9739:UBN2
uniprot id: A0A2U4CCZ4
uniprot id: A0A2U4CD65
uniprot id: A0A2U4CDE5
uniprot id: A0A2U4CDJ1
uniprot id: A0A6J3RXC2
names: Similarity
messages: Belongs to the ubinuclein family.

9739:UPF3B
gene id: 9739:UPF3B
uniprot id: A0A2U4CI39
uniprot id: A0A2U4CI40
uniprot id: A0A2U4CIC6
names: Similarity
messages: Belongs to the RENT3 family.

9739:LOC101325780
gene id: 9739:LOC101325780
uniprot id: A0A2U3V5X7
uniprot id: A0A2U4BQJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

9739:RAPSN
gene id: 9739:RAPSN
uniprot id: A0A2U3V0C9
uniprot id: A0A2U4CF01
uniprot id: A0A2U4CF02
uniprot id: A0A2U4CF04
names: Similarity
messages: Belongs to the RAPsyn family.

9739:MAPK3
gene id: 9739:MAPK3
uniprot id: A0A6J3Q2E5
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
messages: caveola
messages: focal adhesion

9739:KEG93 p13
gene id: 9739:KEG93_p13
uniprot id: B9UD76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 1 family.
messages: Membrane
messages: Mitochondrion inner membrane

9739:NKD2
gene id: 9739:NKD2
uniprot id: A0A6J3R2A8
uniprot id: A0A6J3R3M6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKD family.
messages: Cell autonomous antagonist of the canonical Wnt signaling pathway.
messages: Cell membrane
messages: Cytoplasm

9739:LOC101319785
gene id: 9739:LOC101319785
uniprot id: A0A6J3S8E7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

9739:GK5
gene id: 9739:GK5
uniprot id: A0A2U4B9F4
uniprot id: A0A2U4B9V2
names: Similarity
messages: Belongs to the FGGY kinase family.

9739:ATP11C
gene id: 9739:ATP11C
uniprot id: A0A2U4A0S9
uniprot id: A0A6J3QRM2
uniprot id: A0A6J3QS12
uniprot id: A0A6J3QSF6
uniprot id: A0A6J3QSH8
uniprot id: A0A6J3QT17
uniprot id: A0A6J3QT22
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:LCN6
gene id: 9739:LCN6
uniprot id: A0A6J3RK77
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

9739:ANAPC1
gene id: 9739:ANAPC1
uniprot id: A0A2U4B078
uniprot id: A0A6J3PWJ2
uniprot id: A0A6J3PWJ7
uniprot id: A0A6J3PWK1
uniprot id: A0A6J3PWQ7
uniprot id: A0A6J3PWU7
uniprot id: A0A6J3PX72
names: Similarity
messages: Belongs to the APC1 family.

9739:SLC4A2
gene id: 9739:SLC4A2
uniprot id: A0A6J3RYM6
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Membrane

9739:FAM214A
gene id: 9739:FAM214A
uniprot id: A0A6J3QYI7
uniprot id: A0A6J3QYV4
uniprot id: A0A6J3QZ61
uniprot id: A0A6J3QZF2
uniprot id: A0A6J3QZF7
uniprot id: A0A6J3R0E6
uniprot id: A0A6J3R0E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATOS family.
messages: Nucleus

9739:MGST2
gene id: 9739:MGST2
uniprot id: A0A2U4AN14
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:MED13L
gene id: 9739:MED13L
uniprot id: A0A2U4CJX2
uniprot id: A0A6J3PRM8
uniprot id: A0A6J3PRS8
uniprot id: A0A6J3PS94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

9739:RBBP8
gene id: 9739:RBBP8
uniprot id: A0A6J3PU42
uniprot id: A0A6J3PU68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COM1/SAE2/CtIP family.
messages: Nucleus

9739:NAB2
gene id: 9739:NAB2
uniprot id: A0A6J3S5Y1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAB family.
messages: Homomultimers may associate with EGR1 bound to DNA.
messages: Nucleus

9739:SLC41A1
gene id: 9739:SLC41A1
uniprot id: A0A6J3R1L6
uniprot id: A0A6J3R1V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

9739:SERPINI2
gene id: 9739:SERPINI2
uniprot id: A0A6J3R9Q7
names: Similarity
messages: Belongs to the serpin family.

9739:FAM110D
gene id: 9739:FAM110D
uniprot id: A0A6J3R9Q6
names: Similarity
messages: Belongs to the FAM110 family.

9739:RNASE10
gene id: 9739:RNASE10
uniprot id: W0UVE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

9739:IDE
gene id: 9739:IDE
uniprot id: A0A2U4BPH8
uniprot id: A0A2U4BPI1
uniprot id: A0A2U4BPJ2
uniprot id: A0A2U4BPP7
uniprot id: A0A2U4BPU9
uniprot id: A0A2U4BPV5
uniprot id: A0A6J3Q6Q0
uniprot id: A0A6J3Q764
names: Similarity
messages: Belongs to the peptidase M16 family.

9739:CNP
gene id: 9739:CNP
uniprot id: A0A6J3QM39
uniprot id: A0A6J3QMK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 2H phosphoesterase superfamily. CNPase family.
messages: Exists as monomers and homodimers.
messages: May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin.
messages: Melanosome
messages: Membrane

9739:FAM102A
gene id: 9739:FAM102A
uniprot id: A0A6J3RKJ5
names: Similarity
messages: Belongs to the EEIG family.

9739:FBLL1
gene id: 9739:FBLL1
uniprot id: A0A2U3V1F5
names: Similarity
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.

9739:ABHD2
gene id: 9739:ABHD2
uniprot id: A0A2U4C7K9
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

9739:IGFBP2
gene id: 9739:IGFBP2
uniprot id: A0A6J3RN90
names: Caution
names: Subcellular Location Annotation
names: Subunit
messages: Binds IGF2 more than IGF1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9739:LOC101325788
gene id: 9739:LOC101325788
uniprot id: A0A6J3RFS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFC1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9739:LOC101332434
gene id: 9739:LOC101332434
uniprot id: A0A6J3PRU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCRB/QCR7 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Mitochondrion inner membrane

9739:MAN2A1
gene id: 9739:MAN2A1
uniprot id: A0A2U4BT22
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

9739:LOC101326546
gene id: 9739:LOC101326546
uniprot id: A0A6J3RXQ2
uniprot id: A0A6J3RXQ4
uniprot id: A0A6J3RXU3
uniprot id: A0A6J3RXV5
uniprot id: A0A6J3RYK4
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

9739:INO80C
gene id: 9739:INO80C
uniprot id: A0A2U4AYC8
uniprot id: A0A2U4AYT6
names: Subcellular Location Annotation
messages: Nucleus

9739:GPC1
gene id: 9739:GPC1
uniprot id: A0A6J3RKZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

9739:MAP3K21
gene id: 9739:MAP3K21
uniprot id: A0A2U4BV79
uniprot id: A0A2U4BV80
uniprot id: A0A2U4BV84
uniprot id: A0A2U4BV92
uniprot id: A0A2U4BVD5
uniprot id: A0A2U4BVF9
uniprot id: A0A2U4BVG3
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

9739:HS3ST5
gene id: 9739:HS3ST5
uniprot id: A0A2U4AV05
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9739:LOC117313027
gene id: 9739:LOC117313027
uniprot id: A0A6J3RNF8
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

9739:NANOS2
gene id: 9739:NANOS2
uniprot id: A0A2U3V6F5
names: Similarity
messages: Belongs to the nanos family.

9739:LHFPL1
gene id: 9739:LHFPL1
uniprot id: A0A2U3UZ51
uniprot id: A0A2U3UZH7
names: Subcellular Location Annotation
messages: Membrane

9739:ALG11
gene id: 9739:ALG11
uniprot id: A0A2U3V5S4
uniprot id: A0A2U4BGA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Required for N-linked oligosaccharide assembly.

9739:KDM5C
gene id: 9739:KDM5C
uniprot id: A0A6J3QU69
uniprot id: A0A6J3QU74
uniprot id: A0A6J3QUM5
uniprot id: A0A6J3QUM9
uniprot id: A0A6J3QUU1
uniprot id: A0A6J3QUU5
uniprot id: A0A6J3QUU9
uniprot id: A0A6J3QV42
uniprot id: A0A6J3QV50
uniprot id: A0A6J3QVW2
uniprot id: A0A6J3QVW7
uniprot id: A0A6J3QVX2
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.

9739:PAGE4
gene id: 9739:PAGE4
uniprot id: A0A2U4C0T2
names: Similarity
messages: Belongs to the GAGE family.

9739:LOC101336791
gene id: 9739:LOC101336791
uniprot id: A0A2U4BPB5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9739:ADGRD1
gene id: 9739:ADGRD1
uniprot id: A0A6J3PQZ3
uniprot id: A0A6J3PR56
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:LOC117314509
gene id: 9739:LOC117314509
uniprot id: A0A6J3SAT3
names: Similarity
messages: Belongs to the nucleoplasmin family.

9739:CAND2
gene id: 9739:CAND2
uniprot id: A0A2U3V4H9
uniprot id: A0A2U4C3X1
uniprot id: A0A2U4C3X2
uniprot id: A0A2U4C3Z3
names: Similarity
messages: Belongs to the CAND family.

9739:CHST3
gene id: 9739:CHST3
uniprot id: A0A2U4BEP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

9739:PSMB6
gene id: 9739:PSMB6
uniprot id: A0A6J3QPE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

9739:CD38
gene id: 9739:CD38
uniprot id: A0A2U4AT84
names: Similarity
messages: Belongs to the ADP-ribosyl cyclase family.

9739:CLDN16
gene id: 9739:CLDN16
uniprot id: A0A2U3V8H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9739:CLRN3
gene id: 9739:CLRN3
uniprot id: A0A2U3V3V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

9739:TENT5D
gene id: 9739:TENT5D
uniprot id: A0A2U3V9J2
names: Similarity
messages: Belongs to the TENT family.

9739:CXCL9
gene id: 9739:CXCL9
uniprot id: A0A2U3V826
uniprot id: A0A2U4B509
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

9739:CASP1
gene id: 9739:CASP1
uniprot id: A0A2U3V402
names: Similarity
messages: Belongs to the peptidase C14A family.

9739:GJA4
gene id: 9739:GJA4
uniprot id: A0A2U3V8T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9739:MMP25
gene id: 9739:MMP25
uniprot id: A0A6J3Q103
uniprot id: A0A6J3Q105
uniprot id: A0A6J3Q140
uniprot id: A0A6J3Q1M7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

9739:PTGDR2
gene id: 9739:PTGDR2
uniprot id: A0A6J3RPZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

9739:SF3B5
gene id: 9739:SF3B5
uniprot id: A0A2U4CPU2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SF3B5 family.
messages: Component of the spliceosome B complex.
messages: Nucleus

9739:LOC101329341
gene id: 9739:LOC101329341
uniprot id: A0A2U3V2V0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9739:HINT1
gene id: 9739:HINT1
uniprot id: A0A2U3V3B1
names: Similarity
messages: Belongs to the HINT family.

9739:PLEKHA4
gene id: 9739:PLEKHA4
uniprot id: A0A6J3QIL5
names: Similarity
messages: Belongs to the TUB family.

9739:SLC35F2
gene id: 9739:SLC35F2
uniprot id: A0A2U4A514
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

9739:EYA1
gene id: 9739:EYA1
uniprot id: A0A2U4AIE0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

9739:CAVIN1
gene id: 9739:CAVIN1
uniprot id: A0A6J3QM69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

9739:SCAMP5
gene id: 9739:SCAMP5
uniprot id: A0A6J3QTV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

9739:LOC101330845
gene id: 9739:LOC101330845
uniprot id: A0A6J3QBC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP38 family.
messages: May be required for pre-mRNA splicing.
messages: Nucleus

9739:ADPRM
gene id: 9739:ADPRM
uniprot id: A0A2U3V8H6
names: Similarity
names: Subunit
messages: Belongs to the ADPRibase-Mn family.
messages: Monomer.

9739:POMGNT2
gene id: 9739:POMGNT2
uniprot id: A0A6J3S131
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 61 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:LOC109552834
gene id: 9739:LOC109552834
uniprot id: A0A2U4CPH5
uniprot id: A0A2U4CPJ3
uniprot id: A0A2U4CPK4
uniprot id: A0A2U4CPU3
uniprot id: A0A6J3QXA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COA8 family.
messages: Mitochondrion inner membrane

9739:ZDHHC6
gene id: 9739:ZDHHC6
uniprot id: A0A2U4BQS0
uniprot id: A0A2U4BQX8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9739:LOC101323485
gene id: 9739:LOC101323485
uniprot id: A0A6J3QE51
names: Similarity
messages: Belongs to the HSBP1 family.

9739:ADAMTS8
gene id: 9739:ADAMTS8
uniprot id: A0A6J3RT58
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9739:ZC3HAV1
gene id: 9739:ZC3HAV1
uniprot id: A0A2U4CG85
names: Similarity
messages: Belongs to the ARTD/PARP family.

9739:LOC101320905
gene id: 9739:LOC101320905
uniprot id: A0A2U4A0Z9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9739:SDAD1
gene id: 9739:SDAD1
uniprot id: A0A2U4B505
uniprot id: A0A2U4B5E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDA1 family.
messages: Required for 60S pre-ribosomal subunits export to the cytoplasm.
messages: nucleolus

9739:CD8A
gene id: 9739:CD8A
uniprot id: A0A2U4BWP7
uniprot id: A9Y3I9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9739:ATP6V1C1
gene id: 9739:ATP6V1C1
uniprot id: A0A2U4AHW9
uniprot id: A0A6J3Q900
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits.

9739:POLRMT
gene id: 9739:POLRMT
uniprot id: A0A6J3R7V5
uniprot id: A0A6J3R8G2
uniprot id: A0A6J3R8Z8
uniprot id: A0A6J3R903
uniprot id: A0A6J3RAR7
names: Function
names: Similarity
messages: Belongs to the phage and mitochondrial RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

9739:SPATA18
gene id: 9739:SPATA18
uniprot id: A0A2U4ARG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIEAP family.
messages: Cytoplasm
messages: Membrane
messages: Mitochondrion outer membrane

9739:MED11
gene id: 9739:MED11
uniprot id: A0A2U3V7G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 11 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

9739:ING5
gene id: 9739:ING5
uniprot id: A0A6J3RKS5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

9739:NUDT5
gene id: 9739:NUDT5
uniprot id: A0A2U3V4L3
uniprot id: A0A2U4B6Q0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

9739:FOXL2
gene id: 9739:FOXL2
uniprot id: A0A2U4B9A7
names: Subcellular Location Annotation
messages: Nucleus

9739:LOC101321649
gene id: 9739:LOC101321649
uniprot id: A0A2U4BPI2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

9739:NUP58
gene id: 9739:NUP58
uniprot id: A0A2U4BGU4
uniprot id: A0A2U4BGU7
uniprot id: A0A2U4BGU8
uniprot id: A0A2U4BGU9
uniprot id: A0A2U4BGY0
uniprot id: A0A2U4BH84
uniprot id: A0A2U4BH89
names: Subcellular Location Annotation
messages: nuclear pore complex

9739:ATP5MC1
gene id: 9739:ATP5MC1
uniprot id: A0A2U4AHM7
uniprot id: A0A2U4AHQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

9739:LOC101325973
gene id: 9739:LOC101325973
uniprot id: A0A2U4BS71
uniprot id: A0A2U4BS85
uniprot id: A0A2U4BSI8
uniprot id: A0A6J3RWC3
names: Similarity
messages: Belongs to the CD36 family.

9739:MON1A
gene id: 9739:MON1A
uniprot id: A0A2U4B222
uniprot id: A0A2U4B232
uniprot id: A0A2U4B238
uniprot id: A0A6J3S1V7
names: Function
names: Similarity
messages: Belongs to the MON1/SAND family.
messages: Plays an important role in membrane trafficking through the secretory apparatus.

9739:LOC101328648
gene id: 9739:LOC101328648
uniprot id: A0A2U3V0R9
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

9739:CHRNA2
gene id: 9739:CHRNA2
uniprot id: A0A6J3RFG9
uniprot id: A0A6J3RFZ4
uniprot id: A0A6J3RHR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9739:LOC117313890
gene id: 9739:LOC117313890
uniprot id: A0A6J3S0Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

9739:ATAD2B
gene id: 9739:ATAD2B
uniprot id: A0A2U4BZT0
uniprot id: A0A2U4BZY5
names: Similarity
messages: Belongs to the AAA ATPase family.

9739:LUC7L3
gene id: 9739:LUC7L3
uniprot id: A0A2U4C3J6
uniprot id: A0A6J3QJI1
uniprot id: A0A6J3QJK7
names: Similarity
messages: Belongs to the Luc7 family.

9739:NKX2-8
gene id: 9739:NKX2-8
uniprot id: A0A2U4AF82
names: Subcellular Location Annotation
messages: Nucleus

9739:KCNH8
gene id: 9739:KCNH8
uniprot id: A0A2U4B9U6
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

9739:ADGRB2
gene id: 9739:ADGRB2
uniprot id: A0A6J3PXR3
uniprot id: A0A6J3PXT4
uniprot id: A0A6J3PXT7
uniprot id: A0A6J3PXU7
uniprot id: A0A6J3PXV9
uniprot id: A0A6J3PXX0
uniprot id: A0A6J3PXZ6
uniprot id: A0A6J3PY04
uniprot id: A0A6J3PY09
uniprot id: A0A6J3PY15
uniprot id: A0A6J3PYB1
uniprot id: A0A6J3PYB6
names: Subcellular Location Annotation
messages: Membrane

9739:CDH19
gene id: 9739:CDH19
uniprot id: A0A2U4BFL5
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

9739:C8H11orf87
gene id: 9739:C8H11orf87
uniprot id: A0A6J3RSE3
names: Subcellular Location Annotation
messages: Membrane

9739:TRAPPC6B
gene id: 9739:TRAPPC6B
uniprot id: A0A2U3V450
uniprot id: A0A2U4AEZ8
uniprot id: A0A2U4AF16
uniprot id: A0A2U4AF67
uniprot id: A0A2U4AFG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: cis-Golgi network

9739:PTTG1
gene id: 9739:PTTG1
uniprot id: A0A2U3V2R1
uniprot id: A0A2U4C668
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the securin family.
messages: Cytoplasm
messages: Nucleus

9739:GBX2
gene id: 9739:GBX2
uniprot id: A0A2U3V6E9
uniprot id: A0A2U4ADC1
names: Subcellular Location Annotation
messages: Nucleus

9739:FMNL1
gene id: 9739:FMNL1
uniprot id: A0A6J3QNM9
uniprot id: A0A6J3QP26
uniprot id: A0A6J3QPQ5
names: Similarity
messages: Belongs to the formin homology family.

9739:TMEM208
gene id: 9739:TMEM208
uniprot id: A0A6J3QFS8
uniprot id: A0A6J3QGF1
uniprot id: A0A6J3QGF6
uniprot id: A0A6J3QGW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM208 family.
messages: Endoplasmic reticulum membrane
messages: May function as a negative regulator of endoplasmic reticulum-stress induced autophagy.
messages: Membrane

9739:NXF3
gene id: 9739:NXF3
uniprot id: A0A6J3QT42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NXF family.
messages: Cytoplasm

9739:NT5C3B
gene id: 9739:NT5C3B
uniprot id: A0A6J3QKZ0
uniprot id: A0A6J3QLC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

9739:LOC117313005
gene id: 9739:LOC117313005
uniprot id: A0A6J3RN85
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

9739:PKP2
gene id: 9739:PKP2
uniprot id: A0A2U4BCJ1
names: Similarity
messages: Belongs to the beta-catenin family.

9739:ZFYVE9
gene id: 9739:ZFYVE9
uniprot id: A0A2U4BJG2
uniprot id: A0A2U4BJG8
uniprot id: A0A2U4BJJ0
uniprot id: A0A2U4BJM5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Early endosome membrane

9739:HS3ST1
gene id: 9739:HS3ST1
uniprot id: A0A2U3V7N4
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9739:LOC101337363
gene id: 9739:LOC101337363
uniprot id: A0A2U4CBN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

9739:MINDY1
gene id: 9739:MINDY1
uniprot id: A0A6J3RLM4
uniprot id: A0A6J3RLP0
uniprot id: A0A6J3RN17
uniprot id: A0A6J3RNC7
uniprot id: A0A6J3RND4
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM63 subfamily.
messages: Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins. Has exodeubiquitinase activity and has a preference for long polyubiquitin chains. May play a regulatory role at the level of protein turnover.

9739:LOC117312987
gene id: 9739:LOC117312987
uniprot id: A0A6J3RP82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.
messages: Catalyzes viral DNA integration into the host chromosome, by performing a series of DNA cutting and joining reactions. This enzyme activity takes place after virion entry into a cell and reverse transcription of the RNA genome in dsDNA. The first step in the integration process is 3' processing. This step requires a complex comprising the viral genome, matrix protein and integrase. This complex is called the pre-integration complex (PIC). The integrase protein removes 2 nucleotides from each 3' end of the viral DNA, leaving recessed CA OH's at the 3' ends. In the second step that requires cell division, the PIC enters cell nucleus. In the third step, termed strand transfer, the integrase protein joins the previously processed 3' ends to the 5' ends of strands of target cellular DNA at the site of integration. The last step is viral DNA integration into host chromosome.
messages: Forms the spherical core of the virion that encapsulates the genomic RNA-nucleocapsid complex.
messages: Virion

9739:LOC101336679
gene id: 9739:LOC101336679
uniprot id: A0A6J3R976
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9739:EYS
gene id: 9739:EYS
uniprot id: A0A6J3SA02
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:AMBP
gene id: 9739:AMBP
uniprot id: A0A6J3RHU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Endoplasmic reticulum
messages: In the N-terminal section; belongs to the calycin superfamily. Lipocalin family.
messages: Kunitz-type serine protease inhibitor. Has high catalytic efficiency for F10/blood coagulation factor Xa and may act as an anticoagulant by inhibiting prothrombin activation. Inhibits trypsin and mast cell CMA1/chymase and tryptase proteases.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Monomer. Also occurs as a complex with tryptase in mast cells.
messages: Nucleus membrane
messages: cytosol
messages: extracellular matrix

9739:PMM2
gene id: 9739:PMM2
uniprot id: A0A6J3Q3K7
uniprot id: A0A6J3Q3P0
uniprot id: A0A6J3Q413
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

9739:DENND10
gene id: 9739:DENND10
uniprot id: A0A2U4BR03
uniprot id: A0A2U4BR04
uniprot id: A0A2U4BR67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND10 family.
messages: Endosome
messages: Late endosome

9739:ADAM9
gene id: 9739:ADAM9
uniprot id: A0A2U4A7V3
uniprot id: A0A2U4A8L8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:CPOX
gene id: 9739:CPOX
uniprot id: A0A2U4ABH0
names: Similarity
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Homodimer.

9739:TMEM43
gene id: 9739:TMEM43
uniprot id: A0A6J3S386
uniprot id: A0A6J3S3H0
uniprot id: A0A6J3S4F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM43 family.
messages: Membrane

9739:ADGRG4
gene id: 9739:ADGRG4
uniprot id: A0A2U4A0N0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:SCARB1
gene id: 9739:SCARB1
uniprot id: A0A6J3PR17
uniprot id: A0A6J3PR71
uniprot id: A0A6J3PS32
names: Similarity
messages: Belongs to the CD36 family.

9739:ABCD3
gene id: 9739:ABCD3
uniprot id: A0A2U4A474
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.
messages: Membrane
messages: Peroxisome membrane

9739:ISX
gene id: 9739:ISX
uniprot id: A0A6J3S516
names: Subcellular Location Annotation
messages: Nucleus

9739:UBIAD1
gene id: 9739:UBIAD1
uniprot id: A0A2U4AZR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Membrane

9739:CPA6
gene id: 9739:CPA6
uniprot id: A0A6J3Q9C0
uniprot id: A0A6J3Q9F0
names: Similarity
messages: Belongs to the peptidase M14 family.

9739:WNK2
gene id: 9739:WNK2
uniprot id: A0A6J3RG04
uniprot id: A0A6J3RG09
uniprot id: A0A6J3RG14
uniprot id: A0A6J3RG58
uniprot id: A0A6J3RG63
uniprot id: A0A6J3RG68
uniprot id: A0A6J3RGH6
uniprot id: A0A6J3RGI2
uniprot id: A0A6J3RGU3
uniprot id: A0A6J3RI77
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

9739:ADAMTS20
gene id: 9739:ADAMTS20
uniprot id: A0A6J3S6Y2
uniprot id: A0A6J3S7H7
uniprot id: A0A6J3S8G9
uniprot id: A0A6J3S8R1
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9739:FAM163B
gene id: 9739:FAM163B
uniprot id: A0A2U3V0T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

9739:LOC117313751
gene id: 9739:LOC117313751
uniprot id: A0A6J3RYK1
names: Similarity
messages: Belongs to the intermediate filament family.

9739:TRAK2
gene id: 9739:TRAK2
uniprot id: A0A2U4BNM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the milton family.
messages: Early endosome
messages: Mitochondrion

9739:F2RL2
gene id: 9739:F2RL2
uniprot id: A0A2U3V7A7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9739:AVPR1B
gene id: 9739:AVPR1B
uniprot id: A0A2U3V1Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.

9739:SCN5A
gene id: 9739:SCN5A
uniprot id: A0A6J3RYB6
uniprot id: A0A6J3RYC1
uniprot id: A0A6J3RYE8
uniprot id: A0A6J3RYH1
uniprot id: A0A6J3RYH5
uniprot id: A0A6J3RYL2
uniprot id: A0A6J3RZ94
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

9739:HBQ1
gene id: 9739:HBQ1
uniprot id: A0A2U3V5P2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the globin family.
messages: Heterotetramer of two alpha chains and two beta chains.
messages: Involved in oxygen transport from the lung to the various peripheral tissues.

9739:IL15RA
gene id: 9739:IL15RA
uniprot id: A0A2U4B6J1
uniprot id: A0A6J3R0C3
uniprot id: A0A6J3R0N9
uniprot id: A0A6J3R108
uniprot id: A0A6J3R2G6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:CACNG8
gene id: 9739:CACNG8
uniprot id: A0A6J3QH58
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits.

9739:SSX2IP
gene id: 9739:SSX2IP
uniprot id: A0A6J3RZF9
uniprot id: A0A6J3RZH4
uniprot id: A0A6J3RZL1
uniprot id: A0A6J3RZM6
uniprot id: A0A6J3RZN7
uniprot id: A0A6J3RZS8
uniprot id: A0A6J3RZW5
uniprot id: A0A6J3RZX8
uniprot id: A0A6J3S0I8
uniprot id: A0A6J3S0K1
uniprot id: A0A6J3S0L0
uniprot id: A0A6J3S0M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIP family.
messages: adherens junction
messages: centriolar satellite

9739:SLC18B1
gene id: 9739:SLC18B1
uniprot id: A0A6J3S983
uniprot id: A0A6J3S9I6
uniprot id: A0A6J3S9X0
uniprot id: A0A6J3S9X4
uniprot id: A0A6J3SAP2
names: Subcellular Location Annotation
messages: Membrane

9739:POLR3G
gene id: 9739:POLR3G
uniprot id: A0A2U4AWB7
uniprot id: A0A2U4AWC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC7 RNA polymerase subunit family.
messages: Nucleus

9739:VIP
gene id: 9739:VIP
uniprot id: A0A2U3V2H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

9739:FOXO6
gene id: 9739:FOXO6
uniprot id: A0A6J3PRT5
names: Subcellular Location Annotation
messages: Nucleus

9739:LOC109548838
gene id: 9739:LOC109548838
uniprot id: A0A6J3RE56
names: Subcellular Location Annotation
messages: Membrane

9739:ADD1
gene id: 9739:ADD1
uniprot id: A0A2U4CN80
uniprot id: A0A2U4CN81
uniprot id: A0A2U4CN83
uniprot id: A0A2U4CN86
uniprot id: A0A2U4CN87
uniprot id: A0A2U4CN88
uniprot id: A0A2U4CN94
uniprot id: A0A2U4CN95
uniprot id: A0A2U4CNF4
uniprot id: A0A2U4CNF9
uniprot id: A0A6J3RCA7
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

9739:MUS81
gene id: 9739:MUS81
uniprot id: A0A6J3RQL2
uniprot id: A0A6J3RQW3
uniprot id: A0A6J3RRJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPF family.
messages: Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).
messages: Interacts with EME1.
messages: Nucleus

9739:TMEM54
gene id: 9739:TMEM54
uniprot id: A0A6J3PWL1
uniprot id: A0A6J3PWL9
uniprot id: A0A6J3PWM8
uniprot id: A0A6J3PWQ3
uniprot id: A0A6J3PWR6
uniprot id: A0A6J3PWS5
uniprot id: A0A6J3PWT0
uniprot id: A0A6J3PWV2
uniprot id: A0A6J3PX91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM54 family.
messages: Membrane

9739:ECI1
gene id: 9739:ECI1
uniprot id: A0A6J3Q000
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

9739:NOX4
gene id: 9739:NOX4
uniprot id: A0A6J3RTS4
uniprot id: A0A6J3RTZ9
uniprot id: A0A6J3RU99
names: Subcellular Location Annotation
messages: Membrane

9739:SMC4
gene id: 9739:SMC4
uniprot id: A0A2U3V154
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family.
messages: Chromosome
messages: Nucleus

9739:TRAPPC13
gene id: 9739:TRAPPC13
uniprot id: A0A2U3V956
uniprot id: A0A2U3V957
uniprot id: A0A2U4AX20
uniprot id: A0A2U4AX31
uniprot id: A0A2U4AX56
uniprot id: A0A2U4AXJ9
names: Similarity
names: Subunit
messages: Belongs to the TRAPPC13 family.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.

9739:PRPSAP1
gene id: 9739:PRPSAP1
uniprot id: A0A2U4BM93
uniprot id: A0A2U4BM99
uniprot id: A0A2U4BME4
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

9739:LOC101323402
gene id: 9739:LOC101323402
uniprot id: A0A2U4C5J3
uniprot id: A0A2U4C5L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYCP2 family.
messages: Belongs to the TMEM14 family.
messages: Nucleus

9739:GAA
gene id: 9739:GAA
uniprot id: A0A6J3QJK5
uniprot id: A0A6J3QK67
uniprot id: A0A6J3QK90
uniprot id: A0A6J3QKQ2
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:SAMM50
gene id: 9739:SAMM50
uniprot id: A0A6J3S492
uniprot id: A0A6J3S4F1
uniprot id: A0A6J3S4J8
uniprot id: A0A6J3S5N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAM50/omp85 family.
messages: Mitochondrion outer membrane

9739:TMEM214
gene id: 9739:TMEM214
uniprot id: A0A6J3PXL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TMEM214 family.
messages: Constitutively interacts with CASP4; required for the localization of procaspase 4 to the ER.
messages: Critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis. Required or the activation of CASP4 following endoplasmic reticulum stress.
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:SOAT1
gene id: 9739:SOAT1
uniprot id: A0A6J3R5W0
uniprot id: A0A6J3R6X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:CAPN3
gene id: 9739:CAPN3
uniprot id: A0A6J3QY40
uniprot id: A0A6J3QZ25
uniprot id: A0A6J3R010
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C2 family.
messages: Calcium-regulated non-lysosomal thiol-protease.
messages: Cytoplasm
messages: Homodimer.
messages: nucleolus

9739:AKAP12
gene id: 9739:AKAP12
uniprot id: A0A6J3S9J4
uniprot id: A0A6J3S9T6
names: Subcellular Location Annotation
messages: Membrane

9739:BET1L
gene id: 9739:BET1L
uniprot id: A0A2U3V5W0
uniprot id: A0A6J3RSZ4
names: Subcellular Location Annotation
messages: Membrane

9739:NCAPD3
gene id: 9739:NCAPD3
uniprot id: A0A2U4BWL9
uniprot id: A0A2U4BWM0
uniprot id: A0A2U4BWM4
uniprot id: A0A2U4BWS3
uniprot id: A0A2U4BWS6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the condensin-2 complex.
messages: Nucleus
messages: Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis.

9739:POC5
gene id: 9739:POC5
uniprot id: A0A2U3V5S8
uniprot id: A0A2U4AWM0
uniprot id: A0A2U4AWM7
uniprot id: A0A2U4AWM8
uniprot id: A0A2U4AWN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POC5 family.
messages: Essential for the assembly of the distal half of centrioles, required for centriole elongation.
messages: centriole

9739:RNF112
gene id: 9739:RNF112
uniprot id: A0A6J3QM76
uniprot id: A0A6J3QMX6
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

9739:HINT2
gene id: 9739:HINT2
uniprot id: A0A2U3UZX1
uniprot id: A0A2U4CGQ7
uniprot id: A0A2U4CGR5
names: Caution
names: Similarity
messages: Belongs to the HINT family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:PSMD13
gene id: 9739:PSMD13
uniprot id: A0A2U3V5W4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S11 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP). The regulatory particle is made of a lid composed of 9 subunits including PSMD13, a base containing 6 ATPases and few additional components.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

9739:AKIRIN1
gene id: 9739:AKIRIN1
uniprot id: A0A6J3PUQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

9739:CISD2
gene id: 9739:CISD2
uniprot id: A0A2U3V9S9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CISD protein family. CISD2 subfamily.
messages: Binds 1 [2Fe-2S] cluster.
messages: Endoplasmic reticulum membrane
messages: Homodimer.
messages: Mitochondrion outer membrane
messages: Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy.

9739:ARAF
gene id: 9739:ARAF
uniprot id: A0A6J3QTZ8
uniprot id: A0A6J3QUM6
uniprot id: A0A6J3QUX0
uniprot id: A0A6J3QVN0
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

9739:NME9
gene id: 9739:NME9
uniprot id: A0A6J3RCB5
names: Similarity
messages: Belongs to the NDK family.

9739:NME3
gene id: 9739:NME3
uniprot id: A0A6J3Q173
names: Similarity
messages: Belongs to the NDK family.

9739:PGLYRP3
gene id: 9739:PGLYRP3
uniprot id: A0A2U3VAD6
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

9739:NIPA1
gene id: 9739:NIPA1
uniprot id: A0A2U3V388
uniprot id: A0A2U4B2A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

9739:TIMP4
gene id: 9739:TIMP4
uniprot id: A0A2U3V9Y3
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

9739:GJC2
gene id: 9739:GJC2
uniprot id: A0A6J3R561
uniprot id: A0A6J3R6M6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9739:RFX1
gene id: 9739:RFX1
uniprot id: A0A6J3R660
uniprot id: A0A6J3R897
names: Subcellular Location Annotation
messages: Nucleus

9739:DUSP10
gene id: 9739:DUSP10
uniprot id: A0A2U3V280
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

9739:LOC101323118
gene id: 9739:LOC101323118
uniprot id: A0A6J3R8K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVP26 family.
messages: Membrane

9739:LOC101337707
gene id: 9739:LOC101337707
uniprot id: A0A2U4AID8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCRB/QCR7 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Mitochondrion inner membrane

9739:SFRP2
gene id: 9739:SFRP2
uniprot id: A0A2U3V4Z2
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:CLDN15
gene id: 9739:CLDN15
uniprot id: A0A6J3PZC5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9739:DPH1
gene id: 9739:DPH1
uniprot id: A0A6J3QP17
uniprot id: A0A6J3QPC0
uniprot id: A0A6J3QPP5
names: Similarity
messages: Belongs to the DPH1/DPH2 family. DPH1 subfamily.

9739:F2R
gene id: 9739:F2R
uniprot id: A0A2U4AWL5
uniprot id: A0A2U4AX43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9739:PISD
gene id: 9739:PISD
uniprot id: A0A2U3VAK9
uniprot id: A0A2U4CJM5
uniprot id: A0A2U4CJM7
uniprot id: A0A2U4CJV6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.
messages: Mitochondrion inner membrane

9739:ADGRB1
gene id: 9739:ADGRB1
uniprot id: A0A6J3Q8L3
names: Subcellular Location Annotation
messages: Membrane

9739:OPHN1
gene id: 9739:OPHN1
uniprot id: A0A6J3QR58
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Postsynapse
messages: Presynapse
messages: dendrite

9739:ASRGL1
gene id: 9739:ASRGL1
uniprot id: A0A2U3VA24
names: Similarity
names: Subunit
messages: Belongs to the Ntn-hydrolase family.
messages: Heterodimer of an alpha and beta chain produced by autocleavage. This heterodimer may then dimerize in turn, giving rise to a heterotetramer.

9739:CRYGN
gene id: 9739:CRYGN
uniprot id: A0A6J3RY00
uniprot id: A0A6J3RYR0
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

9739:MMS19
gene id: 9739:MMS19
uniprot id: A0A2U4BQC1
uniprot id: A0A6J3Q5Y4
uniprot id: A0A6J3Q6A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MET18/MMS19 family.
messages: Component of the CIA complex.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.
messages: Nucleus
messages: spindle

9739:PARG
gene id: 9739:PARG
uniprot id: A0A2U4AVJ8
uniprot id: A0A2U4AVQ6
uniprot id: A0A2U4AVW0
uniprot id: A0A2U4AW39
names: Similarity
messages: Belongs to the poly(ADP-ribose) glycohydrolase family.

9739:ZNF496
gene id: 9739:ZNF496
uniprot id: A0A2U4CMX3
uniprot id: A0A6J3R4Z8
uniprot id: A0A6J3R6S3
names: Subcellular Location Annotation
messages: Nucleus

9739:PXN
gene id: 9739:PXN
uniprot id: A0A6J3PRZ4
uniprot id: A0A6J3PS38
uniprot id: A0A6J3PS42
uniprot id: A0A6J3PSJ4
uniprot id: A0A6J3PSJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paxillin family.
messages: cell cortex
messages: cytoskeleton
messages: focal adhesion

9739:MLLT3
gene id: 9739:MLLT3
uniprot id: A0A6J3RH54
uniprot id: A0A6J3RIV9
names: Subcellular Location Annotation
messages: Nucleus

9739:EYA3
gene id: 9739:EYA3
uniprot id: A0A2U4BKZ8
uniprot id: A0A2U4BKZ9
uniprot id: A0A2U4BL03
uniprot id: A0A2U4BL04
uniprot id: A0A2U4BL05
uniprot id: A0A2U4BL16
uniprot id: A0A2U4BL49
uniprot id: A0A2U4BL56
uniprot id: A0A6J3Q071
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

9739:LOC109551917
gene id: 9739:LOC109551917
uniprot id: A0A6J3RCB3
names: Similarity
messages: Belongs to the TRIAP1/MDM35 family.

9739:GFRA2
gene id: 9739:GFRA2
uniprot id: A0A6J3RK29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDNFR family.
messages: Cell membrane
messages: Membrane
messages: Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.

9739:LIG3
gene id: 9739:LIG3
uniprot id: A0A6J3QPK1
uniprot id: A0A6J3QPK7
uniprot id: A0A6J3QPP7
uniprot id: A0A6J3QQ92
uniprot id: A0A6J3QQE5
uniprot id: A0A6J3QQF1
uniprot id: A0A6J3QQS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

9739:ANXA7
gene id: 9739:ANXA7
uniprot id: A0A2U4BEJ8
uniprot id: A0A2U4BEW2
uniprot id: A0A6J3Q8B8
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

9739:CRB1
gene id: 9739:CRB1
uniprot id: A0A2U4A4U5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:TMEM183A
gene id: 9739:TMEM183A
uniprot id: A0A2U3V9K4
uniprot id: A0A2U3ZYX5
uniprot id: A0A2U3ZYY4
uniprot id: A0A2U3ZYZ1
uniprot id: A0A2U3ZYZ6
uniprot id: A0A2U3ZZW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM183 family.
messages: Membrane

9739:LOC109548395
gene id: 9739:LOC109548395
uniprot id: A0A6J3QN87
names: Subcellular Location Annotation
messages: Cytoplasm
messages: nucleolus

9739:SEC24C
gene id: 9739:SEC24C
uniprot id: A0A2U3V189
uniprot id: A0A2U4BEF0
uniprot id: A0A6J3Q7N6
uniprot id: A0A6J3Q7Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

9739:TMEM165
gene id: 9739:TMEM165
uniprot id: A0A2U3V7J7
uniprot id: A0A2U4ARX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

9739:LOC109549193
gene id: 9739:LOC109549193
uniprot id: A0A6J3PU87
uniprot id: A0A6J3PUA8
names: Subcellular Location Annotation
messages: Nucleus

9739:PPP3CA
gene id: 9739:PPP3CA
uniprot id: A0A2U4AM42
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

9739:HTR1D
gene id: 9739:HTR1D
uniprot id: A0A2U3VAN1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Homodimer. Heterodimer with HTR1B.
messages: Membrane

9739:SLC16A12
gene id: 9739:SLC16A12
uniprot id: A0A6J3Q757
names: Subcellular Location Annotation
messages: Membrane

9739:TAP1
gene id: 9739:TAP1
uniprot id: A0A2U3V7V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCB family. MHC peptide exporter (TC 3.A.1.209) subfamily.
messages: Membrane

9739:KRT222
gene id: 9739:KRT222
uniprot id: A0A2U3V893
uniprot id: A0A6J3QM97
names: Similarity
messages: Belongs to the intermediate filament family.

9739:CDS1
gene id: 9739:CDS1
uniprot id: A0A2U3UZS8
uniprot id: A0A2U4AMM5
uniprot id: A0A2U4AMM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Membrane

9739:PTDSS2
gene id: 9739:PTDSS2
uniprot id: A0A6J3RS28
uniprot id: A0A6J3RS83
uniprot id: A0A6J3RST1
uniprot id: A0A6J3RSX1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:ZMPSTE24
gene id: 9739:ZMPSTE24
uniprot id: A0A2U3V2P8
uniprot id: A0A2U4BKB5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.

9739:MAOB
gene id: 9739:MAOB
uniprot id: A0A2U4C100
uniprot id: A0A2U4C187
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flavin monoamine oxidase family.
messages: Mitochondrion outer membrane
messages: Monomer, homo- or heterodimer (containing two subunits of similar size). Each subunit contains a covalently bound flavin. Enzymatically active as monomer.

9739:EPHB4
gene id: 9739:EPHB4
uniprot id: A0A6J3Q1S3
names: Subcellular Location Annotation
messages: Membrane

9739:DDX54
gene id: 9739:DDX54
uniprot id: A0A6J3PRS3
uniprot id: A0A6J3PRX2
uniprot id: A0A6J3PSB9
uniprot id: A0A6J3PSX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
messages: nucleolus

9739:ELN
gene id: 9739:ELN
uniprot id: A0A6J3Q0V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elastin family.
messages: Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle.
messages: extracellular matrix

9739:STAB1
gene id: 9739:STAB1
uniprot id: A0A6J3S254
uniprot id: A0A6J3S2D2
uniprot id: A0A6J3S2Z0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:MBOAT1
gene id: 9739:MBOAT1
uniprot id: A0A2U4C5R6
uniprot id: A0A6J3RZT7
names: Subcellular Location Annotation
messages: Membrane

9739:CAMK2D
gene id: 9739:CAMK2D
uniprot id: A0A2U4AR17
uniprot id: A0A2U4AR19
uniprot id: A0A2U4AR20
uniprot id: A0A2U4AR21
uniprot id: A0A2U4AR24
uniprot id: A0A2U4AR25
uniprot id: A0A2U4AR27
uniprot id: A0A2U4AR30
uniprot id: A0A2U4AR32
uniprot id: A0A2U4ARH0
uniprot id: A0A2U4ARH5
uniprot id: A0A6J3RDQ7
uniprot id: A0A6J3RF98
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

9739:NKX2-2
gene id: 9739:NKX2-2
uniprot id: A0A6J3PZS8
uniprot id: A0A6J3PZT3
names: Subcellular Location Annotation
messages: Nucleus

9739:STK32C
gene id: 9739:STK32C
uniprot id: A0A6J3Q6R5
names: Similarity
messages: Belongs to the protein kinase superfamily.

9739:FUBP1
gene id: 9739:FUBP1
uniprot id: A0A2U3V7J2
uniprot id: A0A2U4A1E4
uniprot id: A0A2U4A1E5
uniprot id: A0A2U4A1E8
uniprot id: A0A2U4A1E9
uniprot id: A0A2U4A1F0
uniprot id: A0A2U4A1F3
uniprot id: A0A2U4A1F4
uniprot id: A0A2U4A1F6
uniprot id: A0A2U4A1F7
uniprot id: A0A2U4A1G1
uniprot id: A0A2U4A1G3
uniprot id: A0A2U4A2C8
uniprot id: A0A2U4A2D4
uniprot id: A0A2U4A2D8
uniprot id: A0A6J3S0L9
uniprot id: A0A6J3S0T1
uniprot id: A0A6J3S1K7
uniprot id: A0A6J3S1N9
uniprot id: A0A6J3S1P7
names: Subcellular Location Annotation
messages: Nucleus

9739:SGF29
gene id: 9739:SGF29
uniprot id: A0A6J3Q3A9
uniprot id: A0A6J3Q3L1
names: Subcellular Location Annotation
messages: Nucleus

9739:LOC117310240
gene id: 9739:LOC117310240
uniprot id: A0A6J3QSM7
names: Subcellular Location Annotation
messages: Nucleus

9739:RNASE12
gene id: 9739:RNASE12
uniprot id: A0A6J3QTW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

9739:TUT1
gene id: 9739:TUT1
uniprot id: A0A6J3RQS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B-like family.
messages: Nucleus speckle
messages: nucleolus

9739:ENGASE
gene id: 9739:ENGASE
uniprot id: A0A6J3QLD8
uniprot id: A0A6J3QLE4
uniprot id: A0A6J3QLJ0
uniprot id: A0A6J3QM18
uniprot id: A0A6J3QM34
uniprot id: A0A6J3QM40
uniprot id: A0A6J3QMJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 85 family.
messages: cytosol

9739:SCD
gene id: 9739:SCD
uniprot id: A0A2U3V4X5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

9739:TBCE
gene id: 9739:TBCE
uniprot id: A0A6J3Q6J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCE family.
messages: Cytoplasm

9739:PPIL6
gene id: 9739:PPIL6
uniprot id: A0A2U4AVW5
uniprot id: A0A2U4AVY1
uniprot id: A0A2U4AVZ6
uniprot id: A0A2U4AWD2
uniprot id: A0A6J3S8W7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

9739:DCST2
gene id: 9739:DCST2
uniprot id: A0A6J3RH05
names: Subcellular Location Annotation
messages: Membrane

9739:CMBL
gene id: 9739:CMBL
uniprot id: A0A2U4CMT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dienelactone hydrolase family.
messages: cytosol

9739:CXCL11
gene id: 9739:CXCL11
uniprot id: A0A2U3V9N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

9739:DYNLRB1
gene id: 9739:DYNLRB1
uniprot id: A0A6J3Q4G8
uniprot id: A0A6J3Q4P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
messages: Belongs to the GAMAD family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs); the composition seems to vary in respect to the IC, LIC and LC composition. The heavy chain homodimer serves as a scaffold for the probable homodimeric assembly of the respective non-catalytic subunits. The ICs and LICs bind directly to the HC dimer and the LCs assemble on the IC dimer.
messages: cytoskeleton

9739:OPLAH
gene id: 9739:OPLAH
uniprot id: A0A6J3Q9E2
uniprot id: A0A6J3QA63
uniprot id: A0A6J3QA91
names: Similarity
messages: Belongs to the oxoprolinase family.

9739:NOS1
gene id: 9739:NOS1
uniprot id: A0A6J3PRR6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOS family.
messages: Binds 1 FAD.
messages: Binds 1 FMN.
messages: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.
messages: dendritic spine
messages: sarcolemma

9739:MAP2K2
gene id: 9739:MAP2K2
uniprot id: A0A6J3R710
names: Similarity
messages: Belongs to the protein kinase superfamily.

9739:RTN4IP1
gene id: 9739:RTN4IP1
uniprot id: A0A2U3V6L3
uniprot id: A0A2U4AVS5
uniprot id: A0A2U4AVT6
uniprot id: A0A2U4AVU2
uniprot id: A0A2U4AW93
uniprot id: A0A6J3S8T8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

9739:PIGO
gene id: 9739:PIGO
uniprot id: A0A2U4CGC2
uniprot id: A0A2U4CGC4
uniprot id: A0A2U4CGC9
uniprot id: A0A2U4CGD0
uniprot id: A0A2U4CGD1
uniprot id: A0A2U4CGH4
uniprot id: A0A6J3RHM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:FBLN7
gene id: 9739:FBLN7
uniprot id: A0A2U4B069
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:DCP2
gene id: 9739:DCP2
uniprot id: A0A2U4BT44
uniprot id: A0A2U4BTA3
names: Similarity
messages: Belongs to the Nudix hydrolase family. DCP2 subfamily.

9739:AGK
gene id: 9739:AGK
uniprot id: A0A6J3RXF5
uniprot id: A0A6J3RXG0
uniprot id: A0A6J3RXG3
uniprot id: A0A6J3RXK6
uniprot id: A0A6J3RXM2
uniprot id: A0A6J3RXM8
uniprot id: A0A6J3RY96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AGK family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

9739:XRCC4
gene id: 9739:XRCC4
uniprot id: A0A2U4AWE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XRCC4-XLF family. XRCC4 subfamily.
messages: Nucleus

9739:CNIH1
gene id: 9739:CNIH1
uniprot id: A0A2U4AEK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

9739:CAND1
gene id: 9739:CAND1
uniprot id: A0A2U3ZYS2
uniprot id: A0A2U3ZYS8
names: Similarity
messages: Belongs to the CAND family.

9739:LOC101332338
gene id: 9739:LOC101332338
uniprot id: A0A2U4CGB7
uniprot id: A0A2U4CGB9
uniprot id: A0A2U4CGC5
uniprot id: A0A2U4CGC6
uniprot id: A0A2U4CGG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

9739:FMO2
gene id: 9739:FMO2
uniprot id: A0A6J3QNI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

9739:MYOD1
gene id: 9739:MYOD1
uniprot id: A0A2U3V1A0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.
messages: Nucleus

9739:LOC101323267
gene id: 9739:LOC101323267
uniprot id: A0A6J3R8W5
names: Similarity
messages: Belongs to the SNURF family.

9739:DOHH
gene id: 9739:DOHH
uniprot id: A0A2U4BTH5
uniprot id: A0A2U4BTM9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the deoxyhypusine hydroxylase family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.

9739:LOC117312790
gene id: 9739:LOC117312790
uniprot id: A0A6J3RLE3
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

9739:PRNP
gene id: 9739:PRNP
uniprot id: A0A2U4BV07
uniprot id: Q58F50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prion family.
messages: Cell membrane
messages: Golgi apparatus
messages: Membrane

9739:SPHKAP
gene id: 9739:SPHKAP
uniprot id: A0A2U4ADC3
names: Similarity
messages: Belongs to the AKAP110 family.

9739:VEGFD
gene id: 9739:VEGFD
uniprot id: A0A2U4AJS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Secreted

9739:C1H1orf174
gene id: 9739:C1H1orf174
uniprot id: A0A2U4AZZ1
uniprot id: A0A2U4AZZ5
uniprot id: A0A2U4B0D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0688 family.
messages: Nucleus

9739:FAM207A
gene id: 9739:FAM207A
uniprot id: A0A6J3RBA7
uniprot id: A0A6J3RBB1
uniprot id: A0A6J3RBI2
uniprot id: A0A6J3RC88
uniprot id: A0A6J3RC93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLX9 family.
messages: nucleolus

9739:RBM48
gene id: 9739:RBM48
uniprot id: A0A2U3UZ82
names: Function
names: Similarity
names: Subunit
messages: As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.
messages: Belongs to the RBM48 family.
messages: Component of the minor spliceosome. Within this complex, interacts with ARMC7 and PRPF8/PRP8.

9739:ITGB4
gene id: 9739:ITGB4
uniprot id: A0A6J3QNR3
uniprot id: A0A6J3QNU8
uniprot id: A0A6J3QPA7
uniprot id: A0A6J3QPK4
uniprot id: A0A6J3QPY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

9739:NCEH1
gene id: 9739:NCEH1
uniprot id: A0A2U3V1U6
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

9739:NIPAL4
gene id: 9739:NIPAL4
uniprot id: A0A6J3R3X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

9739:TMEM245
gene id: 9739:TMEM245
uniprot id: A0A2U4C9E3
uniprot id: A0A2U4C9N2
uniprot id: A0A6J3RI28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

9739:WRN
gene id: 9739:WRN
uniprot id: A0A2U4A7R8
uniprot id: A0A2U4A8I0
uniprot id: A0A6J3QQB9
uniprot id: A0A6J3QR15
uniprot id: A0A6J3QRG9
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

9739:GLO1
gene id: 9739:GLO1
uniprot id: A0A2U4CJ44
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

9739:LOC101322324
gene id: 9739:LOC101322324
uniprot id: A0A2U4C5I8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9739:SORD
gene id: 9739:SORD
uniprot id: A0A2U3V508
uniprot id: A0A2U4BCV0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 1 or 2 Zn(2+) ions per subunit.
messages: Homotetramer.
messages: Mitochondrion membrane
messages: Polyol dehydrogenase that catalyzes the reversible NAD(+)-dependent oxidation of various sugar alcohols. Is active with D-sorbitol (D-glucitol) leading to the C2-oxidized product D-fructose. Is a key enzyme in the polyol pathway that interconverts glucose and fructose via sorbitol, which constitutes an important alternate route for glucose metabolism. May play a role in sperm motility by using sorbitol as an alternative energy source for sperm motility.
messages: flagellum

9739:DDRGK1
gene id: 9739:DDRGK1
uniprot id: A0A2U3V9M0
uniprot id: A0A6J3Q296
names: Similarity
messages: Belongs to the DDRGK1 family.

9739:NXPE3
gene id: 9739:NXPE3
uniprot id: A0A2U4ACS0
uniprot id: A0A6J3RAW7
names: Similarity
messages: Belongs to the NXPE family.

9739:MAML1
gene id: 9739:MAML1
uniprot id: A0A2U4BIT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

9739:LOC109548093
gene id: 9739:LOC109548093
uniprot id: A0A2U4AFY5
names: Caution
names: Similarity
messages: Belongs to the HINT family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:ADGRG6
gene id: 9739:ADGRG6
uniprot id: A0A2U4CPB2
uniprot id: A0A2U4CPD0
uniprot id: A0A2U4CPM0
uniprot id: A0A6J3S9C9
uniprot id: A0A6J3SA07
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:MAGI1
gene id: 9739:MAGI1
uniprot id: A0A6J3S2I4
uniprot id: A0A6J3S2I9
uniprot id: A0A6J3S2J3
uniprot id: A0A6J3S2N7
uniprot id: A0A6J3S2P3
uniprot id: A0A6J3S2P8
uniprot id: A0A6J3S2S5
uniprot id: A0A6J3S2T0
uniprot id: A0A6J3S3C7
uniprot id: A0A6J3S3D3
uniprot id: A0A6J3S3D9
uniprot id: A0A6J3S3P6
uniprot id: A0A6J3S3Q1
uniprot id: A0A6J3S3Q7
names: Subcellular Location Annotation
messages: Membrane

9739:PKNOX1
gene id: 9739:PKNOX1
uniprot id: A0A2U4AC13
uniprot id: A0A2U4ACB8
uniprot id: A0A6J3RBA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

9739:RHOT1
gene id: 9739:RHOT1
uniprot id: A0A2U4ANW1
uniprot id: A0A2U4ANW6
uniprot id: A0A2U4ANY9
uniprot id: A0A2U4APB4
uniprot id: A0A6J3QJZ4
uniprot id: A0A6J3QK50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking.
messages: Mitochondrion outer membrane

9739:CRYGS
gene id: 9739:CRYGS
uniprot id: A0A2U4C8H8
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

9739:NDUFB9
gene id: 9739:NDUFB9
uniprot id: A0A2U3V6T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I LYR family.
messages: Mammalian complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9739:MTO1
gene id: 9739:MTO1
uniprot id: A0A2U4AV61
uniprot id: A0A2U4AVL3
names: Function
names: Similarity
messages: Belongs to the MnmG family.
messages: Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs.

9739:CENPM
gene id: 9739:CENPM
uniprot id: A0A6J3S4K0
uniprot id: A0A6J3S5J7
names: Subcellular Location Annotation
messages: Nucleus

9739:ZRANB2
gene id: 9739:ZRANB2
uniprot id: A0A2U3UZL9
uniprot id: A0A2U4A2Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZRANB2 family.
messages: Nucleus
messages: Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. May interfere with constitutive 5'-splice site selection.

9739:UBA3
gene id: 9739:UBA3
uniprot id: A0A2U3V9W0
uniprot id: A0A2U3VA97
uniprot id: A0A2U4CCH2
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
messages: Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.

9739:TMEM176B
gene id: 9739:TMEM176B
uniprot id: A0A6J3RXR0
uniprot id: A0A6J3RXV3
uniprot id: A0A6J3RYL3
names: Similarity
messages: Belongs to the TMEM176 family.

9739:NRXN3
gene id: 9739:NRXN3
uniprot id: A0A2U4A3F4
uniprot id: A0A2U4A3G1
uniprot id: A0A2U4A3I0
uniprot id: A0A2U4A3I6
uniprot id: A0A2U4A3I9
uniprot id: A0A2U4A3K3
uniprot id: A0A2U4A3K9
uniprot id: A0A2U4A3L4
uniprot id: A0A2U4A3M4
uniprot id: A0A2U4A3M8
uniprot id: A0A2U4A3N5
uniprot id: A0A2U4A3P4
uniprot id: A0A2U4A3Q7
uniprot id: A0A2U4A3R2
uniprot id: A0A2U4A3S1
uniprot id: A0A2U4A3U2
uniprot id: A0A2U4A3V5
uniprot id: A0A2U4A477
uniprot id: A0A2U4A494
uniprot id: A0A2U4A498
uniprot id: A0A2U4A4B0
uniprot id: A0A2U4A4D3
uniprot id: A0A2U4A4I4
uniprot id: A0A6J3QVX5
uniprot id: A0A6J3QW80
uniprot id: A0A6J3QWG1
uniprot id: A0A6J3QWV1
uniprot id: A0A6J3QXU4
uniprot id: A0A6J3QXU8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Presynaptic cell membrane

9739:GSKIP
gene id: 9739:GSKIP
uniprot id: A0A2U3ZYM7
uniprot id: A0A2U3ZYN5
names: Similarity
messages: Belongs to the GSKIP family.

9739:PTCH2
gene id: 9739:PTCH2
uniprot id: A0A6J3SAE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

9739:LOC101320072
gene id: 9739:LOC101320072
uniprot id: A0A6J3Q1C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9739:C11H12orf57
gene id: 9739:C11H12orf57
uniprot id: A0A2U3V153
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0456 family.
messages: Cytoplasm

9739:LOC101330535
gene id: 9739:LOC101330535
uniprot id: A0A6J3PZC8
uniprot id: A0A6J3PZH1
uniprot id: A0A6J3PZJ8
uniprot id: A0A6J3PZW5
names: Subcellular Location Annotation
messages: Membrane

9739:SLC7A1
gene id: 9739:SLC7A1
uniprot id: A0A2U4BGQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

9739:LOC101322944
gene id: 9739:LOC101322944
uniprot id: A0A6J3Q8W9
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

9739:TMEM63C
gene id: 9739:TMEM63C
uniprot id: A0A2U4A4H8
uniprot id: A0A2U4A4K0
uniprot id: A0A6J3QW21
uniprot id: A0A6J3QWJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

9739:LOC101321007
gene id: 9739:LOC101321007
uniprot id: A0A6J3Q5P6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics.
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane
messages: Interacts with chaperones HSP70 and HSP90; this interaction is required for initial targeting to mitochondria.
messages: Membrane
messages: Microsome membrane
messages: Mitochondrion inner membrane
messages: The omega-1 hydroxylase activity is stimulated by cytochrome b5.

9739:SKA1
gene id: 9739:SKA1
uniprot id: A0A2U4BFJ3
names: Similarity
messages: Belongs to the SKA1 family.

9739:MYO5B
gene id: 9739:MYO5B
uniprot id: A0A6J3PTY5
uniprot id: A0A6J3PU35
uniprot id: A0A6J3PUG3
uniprot id: A0A6J3PUX8
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:AGBL4
gene id: 9739:AGBL4
uniprot id: A0A2U4BJC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

9739:USP37
gene id: 9739:USP37
uniprot id: A0A2U4BMR5
uniprot id: A0A6J3RLE2
uniprot id: A0A6J3RM54
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

9739:LOC101318481
gene id: 9739:LOC101318481
uniprot id: A0A2U4C7Y8
names: Subcellular Location Annotation
messages: Membrane

9739:VILL
gene id: 9739:VILL
uniprot id: A0A6J3S0P4
uniprot id: A0A6J3S0P9
uniprot id: A0A6J3S0Q3
uniprot id: A0A6J3S0V6
uniprot id: A0A6J3S1C2
uniprot id: A0A6J3S1T9
names: Similarity
messages: Belongs to the villin/gelsolin family.

9739:LOC101337958
gene id: 9739:LOC101337958
uniprot id: A0A2U3V0E1
names: Subcellular Location Annotation
messages: Nucleus

9739:IL19
gene id: 9739:IL19
uniprot id: A0A6J3R1E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

9739:DCP1B
gene id: 9739:DCP1B
uniprot id: A0A2U4AKW1
names: Similarity
messages: Belongs to the DCP1 family.

9739:ABCG1
gene id: 9739:ABCG1
uniprot id: A0A2U3V3G1
uniprot id: A0A2U3V3T6
uniprot id: A0A2U4A9Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

9739:NR1D1
gene id: 9739:NR1D1
uniprot id: A0A6J3QN43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9739:ABCB6
gene id: 9739:ABCB6
uniprot id: A0A6J3RLP5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Late endosome membrane
messages: Lysosome membrane
messages: Melanosome membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: extracellular exosome
messages: multivesicular body membrane

9739:PRR5L
gene id: 9739:PRR5L
uniprot id: A0A2U4CEE1
uniprot id: A0A2U4CEE4
uniprot id: A0A2U4CEE9
uniprot id: A0A6J3RNN3
names: Similarity
messages: Belongs to the PROTOR family.

9739:TCL1B
gene id: 9739:TCL1B
uniprot id: A0A2U3ZYW9
names: Similarity
messages: Belongs to the TCL1 family.

9739:PDE3A
gene id: 9739:PDE3A
uniprot id: A0A2U4BG86
uniprot id: A0A6J3S777
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9739:PGPEP1
gene id: 9739:PGPEP1
uniprot id: A0A6J3R4Y5
uniprot id: A0A6J3R524
uniprot id: A0A6J3R5K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

9739:LOC101326024
gene id: 9739:LOC101326024
uniprot id: A0A2U4BPN6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9739:MFAP2
gene id: 9739:MFAP2
uniprot id: A0A6J3Q8L1
uniprot id: A0A6J3Q8M0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MFAP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9739:LFNG
gene id: 9739:LFNG
uniprot id: A0A6J3Q4I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9739:AUP1
gene id: 9739:AUP1
uniprot id: A0A2U3V3I1
uniprot id: A0A6J3PVK8
uniprot id: A0A6J3PVL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AUP1 family.
messages: Membrane

9739:MANF
gene id: 9739:MANF
uniprot id: A0A2U3V9F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARMET family.
messages: Secreted

9739:SI
gene id: 9739:SI
uniprot id: A0A2U4C835
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:ESR1
gene id: 9739:ESR1
uniprot id: A0A6J3SA62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Binds DNA as a homodimer.
messages: Membrane
messages: Nucleus
messages: The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.

9739:DLL4
gene id: 9739:DLL4
uniprot id: A0A6J3QYB9
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

9739:DYNC1LI2
gene id: 9739:DYNC1LI2
uniprot id: A0A2U3V6M9
uniprot id: A0A2U4BDH6
uniprot id: A0A2U4BDH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

9739:HSPA4L
gene id: 9739:HSPA4L
uniprot id: A0A2U3V492
names: Similarity
messages: Belongs to the heat shock protein 70 family.

9739:MRPL58
gene id: 9739:MRPL58
uniprot id: A0A2U3V465
names: Subcellular Location Annotation
messages: Mitochondrion

9739:TOM1
gene id: 9739:TOM1
uniprot id: A0A6J3S506
uniprot id: A0A6J3S575
uniprot id: A0A6J3S5C8
uniprot id: A0A6J3S695
names: Similarity
messages: Belongs to the TOM1 family.

9739:CAPZA2
gene id: 9739:CAPZA2
uniprot id: A0A2U4AI12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

9739:LOC117309008
gene id: 9739:LOC117309008
uniprot id: A0A6J3QDI8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9739:GK2
gene id: 9739:GK2
uniprot id: A0A2U4B4T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FGGY kinase family.
messages: Cytoplasm

9739:TTC39C
gene id: 9739:TTC39C
uniprot id: A0A2U4AYM4
uniprot id: A0A2U4AYM5
uniprot id: A0A2U4AZ30
names: Similarity
messages: Belongs to the TTC39 family.

9739:TP73
gene id: 9739:TP73
uniprot id: A0A6J3QDK6
uniprot id: A0A6J3QDX1
uniprot id: A0A6J3QDZ2
uniprot id: A0A6J3QE09
uniprot id: A0A6J3QE18
uniprot id: A0A6J3QE52
uniprot id: A0A6J3QEF6
uniprot id: A0A6J3QEG4
uniprot id: A0A6J3QEG9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Found in a complex with p53/TP53 and CABLES1.
messages: Mitochondrion matrix
messages: Nucleus
messages: PML body
messages: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
messages: centrosome

9739:WDFY1
gene id: 9739:WDFY1
uniprot id: A0A2U4ADL0
uniprot id: A0A2U4ADY2
uniprot id: A0A2U4AED4
uniprot id: A0A6J3RL51
uniprot id: A0A6J3RLJ6
uniprot id: A0A6J3RMG8
uniprot id: A0A6J3RMH2
uniprot id: A0A6J3RMY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Early endosome
messages: Endosome
messages: Golgi apparatus
messages: Membrane
messages: clathrin-coated pit

9739:PTGS2
gene id: 9739:PTGS2
uniprot id: A0A2U3V411
names: Caution
names: Similarity
messages: Belongs to the prostaglandin G/H synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:TYSND1
gene id: 9739:TYSND1
uniprot id: A0A2U4BES6
uniprot id: A0A2U4BES8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1B family.
messages: Peroxisomal protease that mediates both the removal of the leader peptide from proteins containing a PTS2 target sequence and processes several PTS1-containing proteins. Catalyzes the processing of PTS1-proteins involved in the peroxisomal beta-oxidation of fatty acids.
messages: Peroxisome
messages: The full-lengh TYSND1 is the active the proteolytic processing of PTS1- and PTS2-proteins and in self-cleavage, and intermolecular self-cleavage of TYSND1 down-regulates its protease activity.

9739:MRAP
gene id: 9739:MRAP
uniprot id: A0A6J3RBY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRAP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:SLC9A3
gene id: 9739:SLC9A3
uniprot id: A0A6J3R1N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Membrane
messages: Recycling endosome membrane

9739:FOXG1
gene id: 9739:FOXG1
uniprot id: A0A2U4AGD6
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcription repression factor which plays an important role in the establishment of the regional subdivision of the developing brain and in the development of the telencephalon.

9739:RNF5
gene id: 9739:RNF5
uniprot id: A0A6J3RZE8
uniprot id: A0A6J3RZS6
names: Domain
names: Function
names: Subcellular Location Annotation
messages: E3 ubiquitin-protein ligase.
messages: Endoplasmic reticulum membrane
messages: Mitochondrion membrane
messages: The RING-type zinc finger domain is responsible for E3 ligase activity.

9739:CNOT8
gene id: 9739:CNOT8
uniprot id: A0A2U4AH97
uniprot id: A0A2U4AHA2
uniprot id: A0A2U4AHA6
uniprot id: A0A2U4AHA7
uniprot id: A0A2U4AHB1
uniprot id: A0A2U4AHC0
uniprot id: A0A2U4AHC5
uniprot id: A0A2U4AHH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

9739:LOC117307884
gene id: 9739:LOC117307884
uniprot id: A0A6J3PWB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.
messages: Catalyzes viral DNA integration into the host chromosome, by performing a series of DNA cutting and joining reactions. This enzyme activity takes place after virion entry into a cell and reverse transcription of the RNA genome in dsDNA. The first step in the integration process is 3' processing. This step requires a complex comprising the viral genome, matrix protein and integrase. This complex is called the pre-integration complex (PIC). The integrase protein removes 2 nucleotides from each 3' end of the viral DNA, leaving recessed CA OH's at the 3' ends. In the second step that requires cell division, the PIC enters cell nucleus. In the third step, termed strand transfer, the integrase protein joins the previously processed 3' ends to the 5' ends of strands of target cellular DNA at the site of integration. The last step is viral DNA integration into host chromosome.
messages: Forms the spherical core of the virion that encapsulates the genomic RNA-nucleocapsid complex.
messages: Virion

9739:LRRC7
gene id: 9739:LRRC7
uniprot id: A0A6J3S2C7
names: Similarity
messages: Belongs to the LAP (LRR and PDZ) protein family.

9739:MIGA1
gene id: 9739:MIGA1
uniprot id: A0A2U4A1E7
uniprot id: A0A6J3S0T3
names: Similarity
messages: Belongs to the mitoguardin family.

9739:PRDX1
gene id: 9739:PRDX1
uniprot id: A0A2U3V7Z3
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

9739:LOC101328492
gene id: 9739:LOC101328492
uniprot id: A0A6J3QCQ4
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9739:LOC101323336
gene id: 9739:LOC101323336
uniprot id: A0A6J3QTM5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9739:PCYT1A
gene id: 9739:PCYT1A
uniprot id: A0A2U4ABZ7
names: Function
names: Similarity
messages: Belongs to the cytidylyltransferase family.
messages: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.

9739:LOC101326664
gene id: 9739:LOC101326664
uniprot id: A0A6J3QVP3
names: Similarity
messages: Belongs to the GroES chaperonin family.

9739:CCT4
gene id: 9739:CCT4
uniprot id: A0A2U3V7V8
uniprot id: A0A6J3PWY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

9739:OS9
gene id: 9739:OS9
uniprot id: A0A6J3S5K9
uniprot id: A0A6J3S5T8
uniprot id: A0A6J3S5Z7
uniprot id: A0A6J3S6W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OS-9 family.
messages: Endoplasmic reticulum lumen
messages: Lectin involved in the quality control of the secretory pathway. As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, targets misfolded endoplasmic reticulum lumenal glycoproteins for degradation.

9739:BAG6
gene id: 9739:BAG6
uniprot id: A0A2U3UYZ3
uniprot id: A0A2U4AP63
uniprot id: A0A2U4AP67
uniprot id: A0A2U4AP69
uniprot id: A0A2U4AP72
uniprot id: A0A2U4AP82
uniprot id: A0A2U4APL9
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Released extracellularly via exosomes, it is a ligand of the natural killer/NK cells receptor NCR3 and stimulates NK cells cytotoxicity. It may thereby trigger NK cells cytotoxicity against neighboring tumor cells and immature myeloid dendritic cells (DC).
messages: cytosol
messages: extracellular exosome

9739:DMRTA1
gene id: 9739:DMRTA1
uniprot id: A0A2U3V536
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

9739:ZBED6
gene id: 9739:ZBED6
uniprot id: A0A2U4CRR6
names: Subcellular Location Annotation
messages: Nucleus

9739:PSMD8
gene id: 9739:PSMD8
uniprot id: A0A2U3VA78
names: Similarity
messages: Belongs to the proteasome subunit S14 family.

9739:SNAP25
gene id: 9739:SNAP25
uniprot id: A0A2U4BVA0
uniprot id: A0A6J3Q2T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Membrane
messages: Part of the SNARE core complex containing SNAP25, VAMP2 and STX1A; this complex binds CPLX1. Found in a complex containing SYT1, SV2B and syntaxin-1. Found in a ternary complex with STX1A and VAMP8. Interacts with HSC70 and with SYT9, forming a complex with DNAJC5. The interaction with SYT9 is inhibited in presence of calcium. Isoform 1 and isoform 2 interact with BLOC1S6. Interacts with CENPF. Interacts with EQTN. Interacts with HGS. Interacts with KCNB1 (via N-terminus); reduces the voltage-dependent potassium channel KCNB1 activity in pancreatic beta cells. Interacts with OTOF. Interacts with RIMS1. Interacts with SNAPIN. Interacts with STXBP6. Interacts with TRIM9. Interacts with ZDHHC13 (via ANK repeats). Interacts with ZDHHC17 (via ANK repeats). Associates with the BLOC-1 complex. Interacts with PLCL1 (via C2 domain). Interacts with PRRT2; this interaction may impair the formation of the SNARE complex. Interacts with alpha-synuclein/SNCA. Interacts with PRPH2. Interacts with ROM1. Interacts with STX3.
messages: Photoreceptor inner segment
messages: synaptosome
messages: t-SNARE involved in the molecular regulation of neurotransmitter release. Plays an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells.

9739:PLXNC1
gene id: 9739:PLXNC1
uniprot id: A0A2U4CQY4
names: Caution
names: Similarity
messages: Belongs to the plexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:TYMS
gene id: 9739:TYMS
uniprot id: A0A2U4AZ86
names: Similarity
messages: Belongs to the thymidylate synthase family.

9739:ALKBH5
gene id: 9739:ALKBH5
uniprot id: A0A6J3QLS0
names: Subcellular Location Annotation
names: Subunit
messages: Monomer.
messages: Nucleus speckle

9739:LOC101330425
gene id: 9739:LOC101330425
uniprot id: A0A6J3QV29
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

9739:KCMF1
gene id: 9739:KCMF1
uniprot id: A0A2U4BX57
names: Function
names: Similarity
messages: Belongs to the KCMF1 family.
messages: Has intrinsic E3 ubiquitin ligase activity and promotes ubiquitination.

9739:ZFHX4
gene id: 9739:ZFHX4
uniprot id: A0A6J3Q926
uniprot id: A0A6J3Q933
names: Subcellular Location Annotation
messages: Nucleus

9739:LOC109552816
gene id: 9739:LOC109552816
uniprot id: A0A6J3S8H4
names: Subcellular Location Annotation
messages: Membrane
messages: Sarcoplasmic reticulum membrane

9739:LOC117308638
gene id: 9739:LOC117308638
uniprot id: A0A2U3UYW7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

9739:FAM193B
gene id: 9739:FAM193B
uniprot id: A0A6J3R405
uniprot id: A0A6J3R410
uniprot id: A0A6J3R493
uniprot id: A0A6J3R497
uniprot id: A0A6J3R4N4
uniprot id: A0A6J3R4P3
uniprot id: A0A6J3R4Z2
uniprot id: A0A6J3R4Z7
uniprot id: A0A6J3R502
uniprot id: A0A6J3R6E8
names: Similarity
messages: Belongs to the FAM193 family.

9739:TLR4
gene id: 9739:TLR4
uniprot id: A0A2U3UYB7
uniprot id: A0A2U4C8Y1
uniprot id: A0A6J3RF54
uniprot id: A7VJJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

9739:CSF3R
gene id: 9739:CSF3R
uniprot id: A0A2U4BKB9
uniprot id: A0A2U4BKC0
uniprot id: A0A2U4BKD2
uniprot id: A0A2U4BKG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

9739:DMPK
gene id: 9739:DMPK
uniprot id: A0A6J3QBN9
uniprot id: A0A6J3QBV6
uniprot id: A0A6J3QC63
uniprot id: A0A6J3QCD6
uniprot id: A0A6J3QCK8
uniprot id: A0A6J3QCL4
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.

9739:LOC101334165
gene id: 9739:LOC101334165
uniprot id: A0A2U3ZZF2
uniprot id: A0A2U3ZZJ7
uniprot id: A0A2U4A0F8
uniprot id: A0A6J3QW03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFI6/IFI27 family.
messages: Membrane

9739:GPR171
gene id: 9739:GPR171
uniprot id: A0A2U3V8S2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9739:ABCA5
gene id: 9739:ABCA5
uniprot id: A0A2U4BM04
uniprot id: A0A6J3QL34
uniprot id: A0A6J3QLL6
names: Subcellular Location Annotation
messages: Membrane

9739:CENPQ
gene id: 9739:CENPQ
uniprot id: A0A2U4CIV9
uniprot id: A0A2U4CIW6
uniprot id: A0A2U4CIX1
uniprot id: A0A2U4CJ56
uniprot id: A0A6J3RZG4
uniprot id: A0A6J3RZN2
uniprot id: A0A6J3RZW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-Q/OKP1 family.
messages: Nucleus

9739:FGFR2
gene id: 9739:FGFR2
uniprot id: A0A2U4BRG1
uniprot id: A0A6J3Q670
uniprot id: A0A6J3Q673
uniprot id: A0A6J3Q679
uniprot id: A0A6J3Q683
uniprot id: A0A6J3Q6J8
uniprot id: A0A6J3Q6K1
uniprot id: A0A6J3Q6Z8
uniprot id: A0A6J3Q708
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Cell membrane
messages: Membrane

9739:MAPK7
gene id: 9739:MAPK7
uniprot id: A0A6J3QJ67
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

9739:LOC101323856
gene id: 9739:LOC101323856
uniprot id: A0A2U3V8E1
names: Caution
names: Similarity
messages: Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:STC1
gene id: 9739:STC1
uniprot id: A0A2U3V9A7
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.

9739:SPATS2
gene id: 9739:SPATS2
uniprot id: A0A2U4B9Z8
names: Similarity
messages: Belongs to the SPATS2 family.

9739:PBX2
gene id: 9739:PBX2
uniprot id: A0A6J3RZI8
uniprot id: A0A6J3S0E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

9739:SLC13A4
gene id: 9739:SLC13A4
uniprot id: A0A6J3RXH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

9739:RFNG
gene id: 9739:RFNG
uniprot id: A0A6J3QQ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9739:TRAF6
gene id: 9739:TRAF6
uniprot id: A0A2U4CF05
uniprot id: A0A2U4CF07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family. A subfamily.
messages: Lipid droplet
messages: Nucleus
messages: cell cortex

9739:DCP1A
gene id: 9739:DCP1A
uniprot id: A0A2U4CCA1
uniprot id: A0A2U4CCA9
uniprot id: A0A6J3S3E3
names: Similarity
messages: Belongs to the DCP1 family.

9739:DMRT2
gene id: 9739:DMRT2
uniprot id: A0A2U4BAS6
uniprot id: A0A6J3RGV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

9739:MINAR2
gene id: 9739:MINAR2
uniprot id: A0A2U3VA04
names: Similarity
messages: Belongs to the MINAR family.

9739:STX16
gene id: 9739:STX16
uniprot id: A0A6J3Q434
uniprot id: A0A6J3Q435
uniprot id: A0A6J3Q448
uniprot id: A0A6J3Q4A2
uniprot id: A0A6J3Q4B3
uniprot id: A0A6J3Q4H9
uniprot id: A0A6J3Q4J5
uniprot id: A0A6J3Q4T8
uniprot id: A0A6J3Q4U6
uniprot id: A0A6J3Q4U9
names: Similarity
messages: Belongs to the syntaxin family.

9739:MOCS1
gene id: 9739:MOCS1
uniprot id: A0A6J3RZZ3
uniprot id: A0A6J3S116
names: Similarity
messages: In the C-terminal section; belongs to the MoaC family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. MoaA family.

9739:NCR3
gene id: 9739:NCR3
uniprot id: A0A6J3RZ50
uniprot id: A0A6J3RZ97
uniprot id: A0A6J3S058
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the natural cytotoxicity receptor (NCR) family.
messages: Cell membrane
messages: Homodimer in the unliganted form. Interacts with CD3Z. Interacts with and is activated by binding to NCR3LG1. Interacts with and is activated by binding to BAG6.
messages: Membrane

9739:SLC50A1
gene id: 9739:SLC50A1
uniprot id: A0A2U3V7S0
uniprot id: A0A2U3V7S9
uniprot id: A0A2U4B845
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWEET sugar transporter family.
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates sugar transport across membranes.
messages: Membrane

9739:FH
gene id: 9739:FH
uniprot id: A0A2U4A551
names: Function
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Catalyzes the hydration of fumarate to L-malate in the tricarboxylic acid (TCA) cycle to facilitate a transition step in the production of energy in the form of NADH.

9739:ACADL
gene id: 9739:ACADL
uniprot id: A0A2U4BMW0
uniprot id: A0A2U4BN78
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Homotetramer.
messages: Mitochondrion matrix

9739:RUNX3
gene id: 9739:RUNX3
uniprot id: A0A6J3Q317
names: Function
names: Subcellular Location Annotation
messages: Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'-TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
messages: Nucleus

9739:CTTNBP2
gene id: 9739:CTTNBP2
uniprot id: A0A6J3RWX8
names: Subcellular Location Annotation
messages: cell cortex
messages: dendritic spine

9739:APOM
gene id: 9739:APOM
uniprot id: A0A6J3RZ85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family. Highly divergent.
messages: Interacts with LRP2; LRP2 mediates APOM renal uptake and subsequent lysosomal degradation.
messages: Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid.
messages: Secreted

9739:TOR3A
gene id: 9739:TOR3A
uniprot id: A0A2U4CQS6
uniprot id: A0A2U4CR27
names: Similarity
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.

9739:PLPPR5
gene id: 9739:PLPPR5
uniprot id: A0A2U4A175
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

9739:CCNE1
gene id: 9739:CCNE1
uniprot id: A0A2U4BTL8
names: Similarity
messages: Belongs to the cyclin family.

9739:TCF7
gene id: 9739:TCF7
uniprot id: A0A6J3R2T3
uniprot id: A0A6J3R2X0
uniprot id: A0A6J3R2X3
uniprot id: A0A6J3R3C3
uniprot id: A0A6J3R3M7
uniprot id: A0A6J3R506
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

9739:LOC117310440
gene id: 9739:LOC117310440
uniprot id: A0A6J3QU33
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

9739:SLC6A7
gene id: 9739:SLC6A7
uniprot id: A0A6J3R3M3
uniprot id: A0A6J3R3M9
uniprot id: A0A6J3R431
uniprot id: A0A6J3R435
uniprot id: A0A6J3R4D0
uniprot id: A0A6J3R5T3
uniprot id: A0A6J3R5T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

9739:CCNJL
gene id: 9739:CCNJL
uniprot id: A0A2U4C5T6
names: Similarity
messages: Belongs to the cyclin family.

9739:C12H6orf58
gene id: 9739:C12H6orf58
uniprot id: A0A6J3S9U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEG1 family.
messages: Secreted

9739:STK11
gene id: 9739:STK11
uniprot id: A0A6J3R7N1
uniprot id: A0A6J3R7T2
uniprot id: A0A6J3R8Q8
uniprot id: A0A6J3RAJ0
uniprot id: A0A6J3RAJ5
names: Similarity
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. LKB1 subfamily.

9739:ZFP69
gene id: 9739:ZFP69
uniprot id: A0A6J3PT49
uniprot id: A0A6J3PTN4
names: Subcellular Location Annotation
messages: Nucleus

9739:MYO3A
gene id: 9739:MYO3A
uniprot id: A0A2U4B685
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: In the C-terminal section; belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: cytoskeleton

9739:AHSA2P
gene id: 9739:AHSA2P
uniprot id: A0A2U4BY99
names: Similarity
messages: Belongs to the AHA1 family.

9739:ALDH1L2
gene id: 9739:ALDH1L2
uniprot id: A0A2U4A039
uniprot id: A0A6J3S5E2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
messages: In the N-terminal section; belongs to the GART family.

9739:KCNH3
gene id: 9739:KCNH3
uniprot id: A0A6J3S6W8
uniprot id: A0A6J3S809
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

9739:ITIH4
gene id: 9739:ITIH4
uniprot id: A0A6J3S277
uniprot id: A0A6J3S2C4
uniprot id: A0A6J3S2F2
uniprot id: A0A6J3S3C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

9739:TMEM86A
gene id: 9739:TMEM86A
uniprot id: A0A2U4CF20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

9739:TLL2
gene id: 9739:TLL2
uniprot id: A0A2U4BQQ6
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:MED23
gene id: 9739:MED23
uniprot id: A0A2U3V0A0
uniprot id: A0A2U3V0P2
uniprot id: A0A2U4CP26
uniprot id: A0A2U4CP27
uniprot id: A0A2U4CP30
uniprot id: A0A2U4CP37
uniprot id: A0A2U4CP42
uniprot id: A0A2U4CPD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 23 family.
messages: Nucleus

9739:ANO6
gene id: 9739:ANO6
uniprot id: A0A2U4BA94
uniprot id: A0A2U4BA97
uniprot id: A0A2U4BAC8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:CALHM1
gene id: 9739:CALHM1
uniprot id: A0A2U3V613
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

9739:SLC26A1
gene id: 9739:SLC26A1
uniprot id: A0A2U4APX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane
messages: Sodium-independent sulfate anion transporter. Can transport other anions including bicarbonate, thiosulfate and oxalate.

9739:PCMT1
gene id: 9739:PCMT1
uniprot id: A0A2U3V1T5
uniprot id: A0A2U3V1Z8
uniprot id: A0A6J3SA43
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

9739:RNASEK
gene id: 9739:RNASEK
uniprot id: A0A2U3V6D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase K family.
messages: Membrane

9739:DYNLRB2
gene id: 9739:DYNLRB2
uniprot id: A0A2U3V2J1
uniprot id: A0A2U4BT07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
messages: Belongs to the GAMAD family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs); the composition seems to vary in respect to the IC, LIC and LC composition. The heavy chain homodimer serves as a scaffold for the probable homodimeric assembly of the respective non-catalytic subunits. The ICs and LICs bind directly to the HC dimer and the LCs assemble on the IC dimer.
messages: cytoskeleton

9739:MPDU1
gene id: 9739:MPDU1
uniprot id: A0A6J3QNP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPDU1 (TC 2.A.43.3) family.
messages: Membrane
messages: Required for normal utilization of mannose-dolichol phosphate (Dol-P-Man) in the synthesis of N-linked and O-linked oligosaccharides and GPI anchors.

9739:GPRIN1
gene id: 9739:GPRIN1
uniprot id: A0A2U4C0A2
names: Function
messages: May be involved in neurite outgrowth.

9739:ACOX3
gene id: 9739:ACOX3
uniprot id: A0A6J3RCG9
uniprot id: A0A6J3RCI0
uniprot id: A0A6J3RCK3
uniprot id: A0A6J3RD55
uniprot id: A0A6J3RDD7
uniprot id: A0A6J3REY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

9739:LOC117307686
gene id: 9739:LOC117307686
uniprot id: A0A6J3PUL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMDT1/EMRE family.
messages: Component of the uniplex complex. Interacts (via the transmembrane region) with MCU (via the first transmembrane region); the interaction is direct.
messages: Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

9739:IRX5
gene id: 9739:IRX5
uniprot id: A0A6J3QE41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

9739:ANKS6
gene id: 9739:ANKS6
uniprot id: A0A6J3RHZ0
uniprot id: A0A6J3RJK7
names: Function
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

9739:KPNA5
gene id: 9739:KPNA5
uniprot id: A0A2U4AW54
names: Function
names: Similarity
messages: Belongs to the importin alpha family.
messages: Functions in nuclear protein import.

9739:GJA8
gene id: 9739:GJA8
uniprot id: A0A6J3RP93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9739:CD151
gene id: 9739:CD151
uniprot id: A0A6J3RSC7
uniprot id: A0A6J3RSD3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:MEGF10
gene id: 9739:MEGF10
uniprot id: A0A2U4AFY9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:UXT
gene id: 9739:UXT
uniprot id: A0A2U3V9L1
names: Similarity
messages: Belongs to the UXT family.

9739:ZYG11B
gene id: 9739:ZYG11B
uniprot id: A0A2U3V4B2
uniprot id: A0A2U4BJG3
uniprot id: A0A2U4BJK6
names: Similarity
messages: Belongs to the zyg-11 family.

9739:LOC101327569
gene id: 9739:LOC101327569
uniprot id: A0A6J3R0I4
uniprot id: A0A6J3R0V0
uniprot id: A0A6J3R153
uniprot id: A0A6J3R2M4
names: Similarity
messages: Belongs to the SELO family.

9739:LOC101337231
gene id: 9739:LOC101337231
uniprot id: A0A2U3V711
names: Similarity
messages: Belongs to the serpin family.

9739:SCP2
gene id: 9739:SCP2
uniprot id: A0A6J3S794
uniprot id: A0A6J3S799
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Cytoplasm
messages: Interacts with PEX5; the interaction is essential for peroxisomal import.
messages: Mitochondrion

9739:TMEM41A
gene id: 9739:TMEM41A
uniprot id: A0A6J3RA54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM41 family.
messages: Membrane

9739:SNX3
gene id: 9739:SNX3
uniprot id: A0A2U3V3R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome
messages: Endosome
messages: phagosome

9739:NR2F2
gene id: 9739:NR2F2
uniprot id: A0A6J3R002
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9739:NEIL1
gene id: 9739:NEIL1
uniprot id: A0A2U3V5P8
uniprot id: A0A2U4CJG4
uniprot id: A0A2U4CJI5
uniprot id: A0A2U4CJQ2
uniprot id: A0A6J3QZI3
uniprot id: A0A6J3R057
uniprot id: A0A6J3R090
names: Similarity
messages: Belongs to the FPG family.

9739:RNF34
gene id: 9739:RNF34
uniprot id: A0A2U3V0G6
uniprot id: A0A6J3PS30
names: Subcellular Location Annotation
messages: Cell membrane

9739:SND1
gene id: 9739:SND1
uniprot id: A0A6J3RWZ7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs.

9739:THOP1
gene id: 9739:THOP1
uniprot id: A0A6J3R7M9
uniprot id: A0A6J3R818
uniprot id: A0A6J3R8K9
uniprot id: A0A6J3R8L3
uniprot id: A0A6J3RAD3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

9739:LOC109552494
gene id: 9739:LOC109552494
uniprot id: A0A6J3RYG8
names: Similarity
messages: Belongs to the TUB family.

9739:C9
gene id: 9739:C9
uniprot id: A0A2U4AV06
uniprot id: A0A2U4AV36
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted

9739:TSPAN2
gene id: 9739:TSPAN2
uniprot id: A0A6J3RRH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9739:SCG3
gene id: 9739:SCG3
uniprot id: A0A2U4B5D2
uniprot id: A0A2U4B5D5
names: Subcellular Location Annotation
messages: Membrane
messages: Secreted
messages: secretory vesicle membrane

9739:TOM1L1
gene id: 9739:TOM1L1
uniprot id: A0A2U4C646
names: Similarity
messages: Belongs to the TOM1 family.

9739:ZDHHC13
gene id: 9739:ZDHHC13
uniprot id: A0A2U4CE27
uniprot id: A0A2U4CE45
names: Caution
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9739:PTGS1
gene id: 9739:PTGS1
uniprot id: A0A6J3RII3
uniprot id: A0A6J3RJ62
names: Caution
names: Similarity
messages: Belongs to the prostaglandin G/H synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:LOC117307705
gene id: 9739:LOC117307705
uniprot id: A0A6J3PUM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NIP7 family.
messages: Interacts with pre-ribosome complex.
messages: Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.
messages: nucleolus

9739:PI4K2A
gene id: 9739:PI4K2A
uniprot id: A0A2U4BQ75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
messages: Membrane

9739:FGGY
gene id: 9739:FGGY
uniprot id: A0A2U4BXJ4
uniprot id: A0A2U4BXK0
uniprot id: A0A2U4BXK3
uniprot id: A0A2U4BXK4
uniprot id: A0A2U4BXK5
uniprot id: A0A2U4BXK8
uniprot id: A0A2U4BXL9
uniprot id: A0A2U4BXP6
uniprot id: A0A2U4BXQ1
uniprot id: A0A2U4BXQ6
uniprot id: A0A2U4BXR9
uniprot id: A0A6J3S430
names: Similarity
messages: Belongs to the FGGY kinase family.

9739:NKD1
gene id: 9739:NKD1
uniprot id: A0A6J3QDL8
uniprot id: A0A6J3QE56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKD family.
messages: Cell autonomous antagonist of the canonical Wnt signaling pathway.
messages: Cell membrane
messages: Cytoplasm

9739:TMEM8B
gene id: 9739:TMEM8B
uniprot id: A0A6J3RHJ2
uniprot id: A0A6J3RI47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Membrane

9739:CD99L2
gene id: 9739:CD99L2
uniprot id: A0A6J3QSY0
uniprot id: A0A6J3QTY6
names: Similarity
messages: Belongs to the CD99 family.

9739:YWHAB
gene id: 9739:YWHAB
uniprot id: A0A2U4C1R5
names: Similarity
messages: Belongs to the 14-3-3 family.

9739:PRORP
gene id: 9739:PRORP
uniprot id: A0A2U4AF34
names: Similarity
messages: Belongs to the PPR family. P subfamily.

9739:IL10RB
gene id: 9739:IL10RB
uniprot id: A0A2U3V2S3
uniprot id: A0A2U4ABW6
names: Subcellular Location Annotation
messages: Membrane

9739:TMCC1
gene id: 9739:TMCC1
uniprot id: A0A2U3UZ20
uniprot id: A0A2U4B7P2
uniprot id: A0A2U4B7P4
uniprot id: A0A2U4B7Q1
uniprot id: A0A2U4B7Q8
uniprot id: A0A6J3S3F5
names: Similarity
messages: Belongs to the TEX28 family.

9739:GALNTL5
gene id: 9739:GALNTL5
uniprot id: A0A2U4AYI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Membrane

9739:WLS
gene id: 9739:WLS
uniprot id: A0A2U4A276
uniprot id: A0A2U4A280
uniprot id: A0A2U4A282
uniprot id: A0A2U4A339
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the wntless family.
messages: Golgi apparatus membrane
messages: Membrane

9739:GAR1
gene id: 9739:GAR1
uniprot id: A0A6J3RD19
uniprot id: A0A6J3RDM5
uniprot id: A0A6J3RFD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GAR1 family.
messages: Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).
messages: Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.
messages: nucleolus

9739:SNTB1
gene id: 9739:SNTB1
uniprot id: A0A2U4B339
uniprot id: A0A2U4B371
uniprot id: A0A6J3Q836
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

9739:TNFRSF21
gene id: 9739:TNFRSF21
uniprot id: A0A2U4CJ42
uniprot id: A0A2U4CJE1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:MOGAT2
gene id: 9739:MOGAT2
uniprot id: A0A6J3RUT7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:LOC117309713
gene id: 9739:LOC117309713
uniprot id: A0A6J3QQ21
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9739:B4GALT5
gene id: 9739:B4GALT5
uniprot id: A0A2U4C1W6
uniprot id: A0A6J3Q3M7
uniprot id: A0A6J3Q412
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

9739:DPPA2
gene id: 9739:DPPA2
uniprot id: A0A6J3R9H8
names: Subcellular Location Annotation
messages: Nucleus

9739:LOC101323582
gene id: 9739:LOC101323582
uniprot id: A0A6J3REG3
names: Similarity
names: Subunit
messages: Homooctamer.
messages: In the C-terminal section; belongs to the AIR carboxylase family. Class II subfamily.
messages: In the N-terminal section; belongs to the SAICAR synthetase family.

9739:LOC109550349
gene id: 9739:LOC109550349
uniprot id: A0A6J3QKI6
names: Subcellular Location Annotation
messages: Mitochondrion intermembrane space

9739:ICAM2
gene id: 9739:ICAM2
uniprot id: A0A6J3QLT2
uniprot id: A0A6J3QMB0
uniprot id: A0A6J3QMU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. ICAM family.
messages: Membrane

9739:TAS1R2
gene id: 9739:TAS1R2
uniprot id: A0A2U4A0J7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9739:LGR6
gene id: 9739:LGR6
uniprot id: A0A6J3QAS1
uniprot id: A0A6J3QAU9
uniprot id: A0A6J3QBB1
uniprot id: A0A6J3QBT9
names: Subcellular Location Annotation
messages: Membrane

9739:POLE2
gene id: 9739:POLE2
uniprot id: A0A2U3V0L9
uniprot id: A0A2U4AEW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase epsilon subunit B family.
messages: Nucleus
messages: Participates in DNA repair and in chromosomal DNA replication.

9739:MALRD1
gene id: 9739:MALRD1
uniprot id: A0A2U4B6T4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:LOC101334876
gene id: 9739:LOC101334876
uniprot id: A0A6J3Q186
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

9739:RPA1
gene id: 9739:RPA1
uniprot id: A0A2U3V579
uniprot id: A0A2U4AND3
uniprot id: A0A2U4AND7
uniprot id: A0A6J3QNY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
messages: Belongs to the replication factor A protein 1 family.
messages: Component of the heterotrimeric canonical replication protein A complex (RPA).
messages: PML body

9739:MRPL13
gene id: 9739:MRPL13
uniprot id: A0A2U4B3H3
uniprot id: A0A6J3Q846
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

9739:CHMP5
gene id: 9739:CHMP5
uniprot id: A0A2U3V9U9
names: Similarity
messages: Belongs to the SNF7 family.

9739:STMN1
gene id: 9739:STMN1
uniprot id: A0A2U3V5E1
names: Similarity
messages: Belongs to the stathmin family.

9739:NDUFB3
gene id: 9739:NDUFB3
uniprot id: A0A2U3V7G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB3 subunit family.
messages: Mitochondrion inner membrane

9739:OPALIN
gene id: 9739:OPALIN
uniprot id: A0A6J3Q852
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Central nervous system-specific myelin protein that increase myelin genes expression during oligodendrocyte differentiation. Promotes oligodendrocyte terminal differentiation.
messages: Membrane

9739:HESX1
gene id: 9739:HESX1
uniprot id: A0A2U3V7H7
uniprot id: A0A2U4CCK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANF homeobox family.
messages: Nucleus

9739:MYC
gene id: 9739:MYC
uniprot id: A0A2U4B2V6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). Positively regulates transcription of HNRNPA1, HNRNPA2 and PTBP1 which in turn regulate splicing of pyruvate kinase PKM by binding repressively to sequences flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform.
messages: nucleolus
messages: nucleoplasm

9739:TBX15
gene id: 9739:TBX15
uniprot id: A0A2U4A149
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9739:SIKE1
gene id: 9739:SIKE1
uniprot id: A0A2U3VA39
uniprot id: A0A2U4A3K6
names: Similarity
messages: Belongs to the SIKE family.

9739:ALDOC
gene id: 9739:ALDOC
uniprot id: A0A2U3V146
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

9739:SLC35B4
gene id: 9739:SLC35B4
uniprot id: A0A2U4A5V8
uniprot id: A0A6J3RXA0
uniprot id: A0A6J3RY21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

9739:MRPL15
gene id: 9739:MRPL15
uniprot id: A0A2U3V5C8
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

9739:SHFL
gene id: 9739:SHFL
uniprot id: A0A6J3R6R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SHFL family.
messages: Cytoplasm
messages: Nucleus

9739:LOC101319223
gene id: 9739:LOC101319223
uniprot id: A0A2U4C4X0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9739:ERBIN
gene id: 9739:ERBIN
uniprot id: A0A2U4AX00
uniprot id: A0A2U4AX05
uniprot id: A0A2U4AX11
uniprot id: A0A2U4AX17
uniprot id: A0A2U4AX21
uniprot id: A0A2U4AX22
uniprot id: A0A2U4AX34
uniprot id: A0A2U4AX40
uniprot id: A0A2U4AXI0
uniprot id: A0A2U4AXI5
uniprot id: A0A6J3R283
names: Similarity
messages: Belongs to the LAP (LRR and PDZ) protein family.

9739:LOC117312755
gene id: 9739:LOC117312755
uniprot id: A0A6J3RM05
names: Similarity
messages: Belongs to the NUT family.

9739:LOC101337631
gene id: 9739:LOC101337631
uniprot id: A0A2U4AVD6
uniprot id: A0A2U4AVE3
uniprot id: A0A2U4AVE7
uniprot id: A0A2U4AVG4
uniprot id: A0A2U4AVV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Endoplasmic reticulum

9739:SMS
gene id: 9739:SMS
uniprot id: A0A6J3QRN6
uniprot id: A0A6J3QS50
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

9739:DICER1
gene id: 9739:DICER1
uniprot id: A0A2U3ZZ05
names: Function
names: Similarity
messages: Belongs to the helicase family. Dicer subfamily.
messages: Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, also called RNA interference, controls the elimination of transcripts from mobile and repetitive DNA elements of the genome but also the degradation of exogenous RNA of viral origin for instance. The miRNA pathway on the other side is a mean to specifically regulate the expression of target genes.

9739:LOC101330561
gene id: 9739:LOC101330561
uniprot id: A0A2U4B370
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

9739:DUSP3
gene id: 9739:DUSP3
uniprot id: A0A6J3QN48
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

9739:YTHDC1
gene id: 9739:YTHDC1
uniprot id: A0A6J3RDZ7
uniprot id: A0A6J3RE18
uniprot id: A0A6J3REK4
uniprot id: A0A6J3RGA8
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

9739:EFEMP2
gene id: 9739:EFEMP2
uniprot id: A0A6J3RR33
uniprot id: A0A6J3RRK8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:LOC101337002
gene id: 9739:LOC101337002
uniprot id: A0A6J3QSL6
names: Similarity
messages: Belongs to the SMEK family.

9739:TRAP1
gene id: 9739:TRAP1
uniprot id: A0A6J3Q1U0
uniprot id: A0A6J3Q2A2
names: Similarity
messages: Belongs to the heat shock protein 90 family.

9739:MUSTN1
gene id: 9739:MUSTN1
uniprot id: A0A6J3RYP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MUSTANG family.
messages: Nucleus

9739:PRKD3
gene id: 9739:PRKD3
uniprot id: A0A2U4BZ22
uniprot id: A0A2U4BZ23
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by DAG and phorbol esters.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Cytoplasm
messages: Membrane

9739:STRADB
gene id: 9739:STRADB
uniprot id: A0A2U4BN95
uniprot id: A0A2U4BNL5
uniprot id: A0A2U4BNM0
uniprot id: A0A6J3RNG8
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.

9739:TPP2
gene id: 9739:TPP2
uniprot id: A0A2U3UZ08
uniprot id: A0A2U4A6H7
uniprot id: A0A2U4A6H8
uniprot id: A0A2U4A6M1
uniprot id: A0A6J3QBB3
names: Caution
names: Similarity
messages: Belongs to the peptidase S8 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:TBPL1
gene id: 9739:TBPL1
uniprot id: A0A2U4CPQ0
names: Similarity
names: Subunit
messages: Belongs to the TBP family.
messages: Binds TFIIA and TFIIB.

9739:NGRN
gene id: 9739:NGRN
uniprot id: A0A2U4C702
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the neugrin family.
messages: Forms a regulatory protein-RNA complex, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mt-rRNA. Interacts with 16S mt-rRNA; this interaction is direct.
messages: Mitochondrion membrane
messages: Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.

9739:RUNX2
gene id: 9739:RUNX2
uniprot id: A0A2U4CJA1
uniprot id: A0A6J3RZJ1
uniprot id: A0A6J3RZP6
uniprot id: A0A6J3RZY3
uniprot id: A0A6J3S0K6
names: Function
names: Subcellular Location Annotation
messages: Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'-TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
messages: Nucleus

9739:TMEM87B
gene id: 9739:TMEM87B
uniprot id: A0A2U3UYZ7
names: Subcellular Location Annotation
messages: Membrane

9739:LOC101328023
gene id: 9739:LOC101328023
uniprot id: A0A6J3RRC8
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

9739:POP7
gene id: 9739:POP7
uniprot id: A0A6J3Q371
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone-like Alba family.
messages: Component of nuclear RNase P and RNase MRP complexes. RNase P consists of a catalytic RNA moiety and 10 different protein chains; POP1, POP4, POP5, POP7, RPP14, RPP21, RPP25, RPP30, RPP38 and RPP40. Within the RNase P complex, POP1, POP7 and RPP25 form the 'finger' subcomplex, POP5, RPP14, RPP40 and homodimeric RPP30 form the 'palm' subcomplex, and RPP21, POP4 and RPP38 form the 'wrist' subcomplex. All subunits of the RNase P complex interact with the catalytic RNA. Several subunits of RNase P are also part of the RNase MRP complex. RNase MRP consists of a catalytic RNA moiety and about 8 protein subunits; POP1, POP7, RPP25, RPP30, RPP38, RPP40 and possibly also POP4 and POP5. Interacts with SMN1. POP7 forms a heterodimer with RPP25 that binds to the P3 stem loop of the catalytic RNA.
messages: Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences.
messages: Cytoplasmic granule
messages: nucleolus

9739:ERGIC3
gene id: 9739:ERGIC3
uniprot id: A0A2U3V7N3
uniprot id: A0A2U3V7N7
uniprot id: A0A2U4CLM1
uniprot id: A0A2U4CLM3
uniprot id: A0A2U4CLM8
uniprot id: A0A2U4CLU5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

9739:LOC101337118
gene id: 9739:LOC101337118
uniprot id: A0A6J3PVP4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:FAM133A
gene id: 9739:FAM133A
uniprot id: A0A2U4B3K5
names: Similarity
messages: Belongs to the FAM133 family.

9739:CMC4
gene id: 9739:CMC4
uniprot id: A0A2U4BIH1
uniprot id: A0A2U4BIN3
names: Similarity
messages: Belongs to the CMC4 family.

9739:DDX58
gene id: 9739:DDX58
uniprot id: A0A6J3RK82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

9739:MRAP2
gene id: 9739:MRAP2
uniprot id: A0A6J3SAC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRAP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:MYSM1
gene id: 9739:MYSM1
uniprot id: A0A2U4BXL3
uniprot id: A0A2U4BXL5
uniprot id: A0A2U4BXL8
uniprot id: A0A2U4BXM2
uniprot id: A0A2U4BXS3
names: Similarity
messages: Belongs to the peptidase M67A family. MYSM1 subfamily.

9739:NOTO
gene id: 9739:NOTO
uniprot id: A0A2U3UZ62
names: Subcellular Location Annotation
messages: Nucleus

9739:RAB43
gene id: 9739:RAB43
uniprot id: A0A6J3S3B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane

9739:TAZ
gene id: 9739:TAZ
uniprot id: A0A6J3QSW5
uniprot id: A0A6J3QTG8
uniprot id: A0A6J3QTH3
uniprot id: A0A6J3QTN5
uniprot id: A0A6J3QTP1
uniprot id: A0A6J3QTW1
uniprot id: A0A6J3QTW5
uniprot id: A0A6J3QUI6
uniprot id: A0A6J3QUJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acyltransferase which is required to remodel newly synthesized phospholipid cardiolipin, a key component of the mitochondrial inner membrane. Required for the initiation of mitophagy. Required to ensure progression of spermatocytes through meiosis.
messages: Associates with multiple protein complexes.
messages: Belongs to the taffazin family.
messages: Mitochondrion inner membrane
messages: Mitochondrion outer membrane

9739:MEGF8
gene id: 9739:MEGF8
uniprot id: A0A6J3QJB7
uniprot id: A0A6J3QJE4
uniprot id: A0A6J3QJU7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:ILF3
gene id: 9739:ILF3
uniprot id: A0A6J3R5Y5
uniprot id: A0A6J3R629
uniprot id: A0A6J3R6K8
uniprot id: A0A6J3R8P9
uniprot id: A0A6J3R8Q3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9739:RRAGA
gene id: 9739:RRAGA
uniprot id: A0A2U4BB78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

9739:GPR182
gene id: 9739:GPR182
uniprot id: A0A6J3S5Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9739:LOC117312182
gene id: 9739:LOC117312182
uniprot id: A0A6J3RBK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P33MONOX family.
messages: Cytoplasm
messages: Interacts with NELFB, NOL12 and PRNP.
messages: Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth.

9739:NCOR1
gene id: 9739:NCOR1
uniprot id: A0A2U4C2H4
uniprot id: A0A2U4C2H9
uniprot id: A0A2U4C2I0
uniprot id: A0A2U4C2I4
uniprot id: A0A2U4C2I8
uniprot id: A0A2U4C2J3
uniprot id: A0A2U4C2K6
uniprot id: A0A2U4C2L6
uniprot id: A0A2U4C2M7
uniprot id: A0A2U4C2P2
uniprot id: A0A2U4C2Q5
uniprot id: A0A2U4C2R2
names: Similarity
messages: Belongs to the N-CoR nuclear receptor corepressors family.

9739:CSNK2B
gene id: 9739:CSNK2B
uniprot id: A0A2U3UYY9
uniprot id: A0A2U4AP91
uniprot id: A0A6J3S069
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Participates in Wnt signaling.
messages: Tetramer of two alpha and two beta subunits.

9739:RIF1
gene id: 9739:RIF1
uniprot id: A0A2U4AA22
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

9739:PDE8B
gene id: 9739:PDE8B
uniprot id: A0A2U4AWL2
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9739:BMP1
gene id: 9739:BMP1
uniprot id: A0A6J3RFQ4
uniprot id: A0A6J3RG78
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:PAX3
gene id: 9739:PAX3
uniprot id: A0A6J3RL60
uniprot id: A0A6J3RLT1
uniprot id: A0A6J3RMH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

9739:RDH10
gene id: 9739:RDH10
uniprot id: A0A2U3V0R2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9739:LOC101318179
gene id: 9739:LOC101318179
uniprot id: A0A2U3VAJ5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9739:GART
gene id: 9739:GART
uniprot id: A0A2U3V3C9
uniprot id: A0A2U4AC04
uniprot id: A0A2U4AC45
uniprot id: A0A6J3RAX7
names: Similarity
messages: In the C-terminal section; belongs to the GART family.
messages: In the N-terminal section; belongs to the GARS family.
messages: In the central section; belongs to the AIR synthase family.

9739:SPSB4
gene id: 9739:SPSB4
uniprot id: A0A2U4B9D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

9739:ENDOG
gene id: 9739:ENDOG
uniprot id: A0A6J3RJW4
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

9739:CFL2
gene id: 9739:CFL2
uniprot id: A0A2U4AF62
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

9739:FAM189B
gene id: 9739:FAM189B
uniprot id: A0A6J3RF44
uniprot id: A0A6J3RF66
uniprot id: A0A6J3RFL6
names: Similarity
messages: Belongs to the ENTREP family.

9739:TPRG1
gene id: 9739:TPRG1
uniprot id: A0A6J3RB91
names: Similarity
messages: Belongs to the TPRG1 family.

9739:ENAH
gene id: 9739:ENAH
uniprot id: A0A2U4A4I3
uniprot id: A0A2U4A4I9
uniprot id: A0A2U4A4J0
uniprot id: A0A2U4A4L1
uniprot id: A0A2U4A5C3
uniprot id: A0A6J3QXD8
uniprot id: A0A6J3QXE3
uniprot id: A0A6J3QYY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ena/VASP family.
messages: cytoskeleton

9739:GOLPH3
gene id: 9739:GOLPH3
uniprot id: A0A2U4AY62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

9739:CLP1
gene id: 9739:CLP1
uniprot id: A0A2U4CF14
uniprot id: A0A2U4CF63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Clp1 family. Clp1 subfamily.
messages: Component of the tRNA splicing endonuclease complex, composed of CLP1, TSEN2, TSEN15, TSEN34 and TSEN54. Component of pre-mRNA cleavage complex II (CF-II). Also associates with numerous components of the pre-mRNA cleavage complex I (CF-I/CFIm), including NUDT21, CPSF2, CPSF3, CPSF6 and CPSF7. Interacts with CSTF2 and SYMPK.
messages: Nucleus
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; this phosphorylation event is a prerequisite for the subsequent ligation of the two exon halves and the production of a mature tRNA. Component of the pre-mRNA cleavage complex II (CF-II), which seems to be required for mRNA 3'-end formation. Also phosphorylates the 5'-terminus of exogenously introduced short interfering RNAs (siRNAs), which is a necessary prerequisite for their incorporation into the RNA-induced silencing complex (RISC). However, endogenous siRNAs and microRNAs (miRNAs) that are produced by the cleavage of dsRNA precursors by DICER1 already contain a 5'-phosphate group, so this protein may be dispensible for normal RNA-mediated gene silencing.

9739:HSD17B3
gene id: 9739:HSD17B3
uniprot id: A0A2U3V803
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9739:TAC4
gene id: 9739:TAC4
uniprot id: A0A6J3QMC7
names: Similarity
messages: Belongs to the tachykinin family.

9739:HCRTR2
gene id: 9739:HCRTR2
uniprot id: A0A2U4B159
uniprot id: A0A2U4B161
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9739:CAPN15
gene id: 9739:CAPN15
uniprot id: A0A6J3PYY2
uniprot id: A0A6J3PYZ8
uniprot id: A0A6J3PZ68
uniprot id: A0A6J3PZ73
uniprot id: A0A6J3PZJ5
names: Similarity
messages: Belongs to the peptidase C2 family.

9739:CNIH3
gene id: 9739:CNIH3
uniprot id: A0A6J3QXG5
uniprot id: A0A6J3QYV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

9739:SLC16A14
gene id: 9739:SLC16A14
uniprot id: A0A2U4ADS7
names: Subcellular Location Annotation
messages: Membrane

9739:PRKAR1A
gene id: 9739:PRKAR1A
uniprot id: A0A2U3V3T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

9739:PTK2B
gene id: 9739:PTK2B
uniprot id: A0A6J3RFG6
uniprot id: A0A6J3RFL3
uniprot id: A0A6J3RFZ0
uniprot id: A0A6J3RGB1
uniprot id: A0A6J3RHQ9
names: Subcellular Location Annotation
messages: Cell membrane
messages: cell cortex
messages: focal adhesion

9739:MYO1F
gene id: 9739:MYO1F
uniprot id: A0A6J3R683
uniprot id: A0A6J3R778
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

9739:DHX9
gene id: 9739:DHX9
uniprot id: A0A2U4CRR5
uniprot id: A0A2U4CS20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DEAH subfamily.
messages: Nucleus

9739:MCCC2
gene id: 9739:MCCC2
uniprot id: A0A2U4AWV3
uniprot id: A0A2U4AWV4
names: Similarity
messages: Belongs to the AccD/PCCB family.

9739:HOXD10
gene id: 9739:HOXD10
uniprot id: A0A2U3V0Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

9739:EIF4G1
gene id: 9739:EIF4G1
uniprot id: A0A6J3R9B8
uniprot id: A0A6J3R9J3
uniprot id: A0A6J3R9J8
uniprot id: A0A6J3RA23
uniprot id: A0A6J3RA27
uniprot id: A0A6J3RAF9
uniprot id: A0A6J3RAG4
uniprot id: A0A6J3RC59
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4G family.

9739:LOC117307918
gene id: 9739:LOC117307918
uniprot id: A0A6J3PWY1
names: Similarity
messages: Belongs to the TTC39 family.

9739:SIDT2
gene id: 9739:SIDT2
uniprot id: A0A6J3RTV0
uniprot id: A0A6J3RTY7
uniprot id: A0A6J3RU71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SID1 family.
messages: Membrane

9739:IGF1
gene id: 9739:IGF1
uniprot id: A0A2U3V677
uniprot id: A0A2U3V6K4
uniprot id: A0A3Q8C7S8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the insulin family.
messages: Forms a ternary complex with IGFR1 and ITGAV:ITGB3. Forms a ternary complex with IGFR1 and ITGA6:ITGB4.
messages: Secreted

9739:LOC109549067
gene id: 9739:LOC109549067
uniprot id: A0A2U4AVY9
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

9739:LOC101329976
gene id: 9739:LOC101329976
uniprot id: A0A6J3Q830
uniprot id: A0A6J3Q8H4
names: Subcellular Location Annotation
messages: Nucleus

9739:MAGI3
gene id: 9739:MAGI3
uniprot id: A0A6J3RSS4
uniprot id: A0A6J3RT44
names: Subcellular Location Annotation
messages: Membrane

9739:NTSR2
gene id: 9739:NTSR2
uniprot id: A0A2U4BXY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9739:KDM3A
gene id: 9739:KDM3A
uniprot id: A0A6J3PWE2
uniprot id: A0A6J3PWE5
uniprot id: A0A6J3PWK0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM2 histone demethylase family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code.
messages: Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors.
messages: Nucleus
messages: The JmjC domain and the C6-type zinc-finger are required for the demethylation activity.

9739:MTERF1
gene id: 9739:MTERF1
uniprot id: A0A2U3V6S7
uniprot id: A0A2U4ANK5
names: Similarity
messages: Belongs to the mTERF family.

9739:ABCG8
gene id: 9739:ABCG8
uniprot id: A0A2U4BY52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

9739:LOC101320618
gene id: 9739:LOC101320618
uniprot id: A0A2U3V1H4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9739:IL17D
gene id: 9739:IL17D
uniprot id: A0A2U4BGZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

9739:ARID3A
gene id: 9739:ARID3A
uniprot id: A0A6J3R8B4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer.
messages: Nucleus
messages: Transcription factor.

9739:UBA2
gene id: 9739:UBA2
uniprot id: A0A2U4BTP4
uniprot id: A0A2U4BTU4
uniprot id: A0A6J3QHN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ubiquitin-activating E1 family.
messages: Heterodimer of SAE1 and UBA2/SAE2. The heterodimer corresponds to the two domains that are encoded on a single polypeptide chain in ubiquitin-activating enzyme E1. Interacts with UBE2I.
messages: Nucleus
messages: The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

9739:NDNF
gene id: 9739:NDNF
uniprot id: A0A6J3RCU2
names: Subcellular Location Annotation
messages: Secreted

9739:ZNF711
gene id: 9739:ZNF711
uniprot id: A0A2U4B3H5
uniprot id: A0A2U4B3H6
uniprot id: A0A2U4B3X2
uniprot id: A0A6J3QTF8
names: Subcellular Location Annotation
messages: Nucleus

9739:LOC101329648
gene id: 9739:LOC101329648
uniprot id: A0A2U3V4Y0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9739:GCFC2
gene id: 9739:GCFC2
uniprot id: A0A2U4BWZ0
uniprot id: A0A2U4BX52
names: Similarity
messages: Belongs to the GCF family.

9739:CETN1
gene id: 9739:CETN1
uniprot id: A0A2U3V4U5
names: Similarity
messages: Belongs to the centrin family.

9739:TMEM121
gene id: 9739:TMEM121
uniprot id: A0A6J3QVU8
names: Similarity
messages: Belongs to the TMEM121 family.

9739:LOC101338541
gene id: 9739:LOC101338541
uniprot id: A0A2U3V9J7
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: acrosome inner membrane

9739:RPL35A
gene id: 9739:RPL35A
uniprot id: A0A2U3VA27
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

9739:RPL10
gene id: 9739:RPL10
uniprot id: A0A6J3QTX0
uniprot id: A0A6J3QUJ5
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

9739:IMMP2L
gene id: 9739:IMMP2L
uniprot id: A0A2U4AJ32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26 family. IMP2 subfamily.
messages: Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO.
messages: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
messages: Membrane
messages: Mitochondrion inner membrane

9739:CASP9
gene id: 9739:CASP9
uniprot id: A0A6J3Q982
uniprot id: A0A6J3Q987
uniprot id: A0A6J3Q9K6
names: Similarity
messages: Belongs to the peptidase C14A family.

9739:LOC101333735
gene id: 9739:LOC101333735
uniprot id: A0A2U4BIJ5
uniprot id: A0A2U4BIK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly.
messages: Mitochondrion inner membrane

9739:LOC117312628
gene id: 9739:LOC117312628
uniprot id: A0A6J3RH40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

9739:LOC101325751
gene id: 9739:LOC101325751
uniprot id: A0A6J3S4I5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase F chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

9739:PSKH1
gene id: 9739:PSKH1
uniprot id: A0A2U4BDP5
uniprot id: A0A6J3QG80
uniprot id: A0A6J3QGP6
names: Similarity
messages: Belongs to the protein kinase superfamily.

9739:PSMC5
gene id: 9739:PSMC5
uniprot id: A0A2U3V525
uniprot id: A0A2U4C333
uniprot id: A0A2U4C365
names: Similarity
messages: Belongs to the AAA ATPase family.

9739:GCK
gene id: 9739:GCK
uniprot id: A0A6J3RW13
uniprot id: A0A6J3RW16
uniprot id: A0A6J3RW18
uniprot id: A0A6J3RW36
uniprot id: A0A6J3RW42
uniprot id: A0A6J3RW44
uniprot id: A0A6J3RWL6
uniprot id: A0A6J3RWM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hexokinase family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: cytosol

9739:GMFB
gene id: 9739:GMFB
uniprot id: A0A2U4AER7
uniprot id: A0A6J3QWZ4
uniprot id: A0A6J3QX92
uniprot id: A0A6J3QXE9
uniprot id: A0A6J3QXX3
names: Similarity
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.

9739:PROX2
gene id: 9739:PROX2
uniprot id: A0A2U3V6W6
names: Subcellular Location Annotation
messages: Nucleus

9739:ALDH1A2
gene id: 9739:ALDH1A2
uniprot id: A0A6J3QYN6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

9739:GDPGP1
gene id: 9739:GDPGP1
uniprot id: A0A2U4C6Z7
uniprot id: A0A2U4C708
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDPGP1 family.
messages: Cytoplasm
messages: Specific and highly efficient GDP-D-glucose phosphorylase regulating the levels of GDP-D-glucose in cells.

9739:LOC117312762
gene id: 9739:LOC117312762
uniprot id: A0A6J3RKG5
names: Similarity
messages: Belongs to the NUT family.

9739:NELFE
gene id: 9739:NELFE
uniprot id: A0A2U4AP94
uniprot id: A0A2U4AP95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM NELF-E family.
messages: Chromosome
messages: Nucleus

9739:MPV17L2
gene id: 9739:MPV17L2
uniprot id: A0A2U3V9W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

9739:MST1R
gene id: 9739:MST1R
uniprot id: A0A2U4B206
uniprot id: A0A2U4B212
uniprot id: A0A2U4B218
uniprot id: A0A2U4B221
uniprot id: A0A2U4B223
uniprot id: A0A2U4B228
uniprot id: A0A2U4B233
uniprot id: A0A2U4B251
uniprot id: A0A2U4B261
uniprot id: A0A2U4B2F3
uniprot id: A0A2U4B2F6
uniprot id: A0A2U4B2G1
uniprot id: A0A6J3S1Y8
uniprot id: A0A6J3S2M3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:PAMR1
gene id: 9739:PAMR1
uniprot id: A0A2U4CEG0
uniprot id: A0A2U4CEG2
uniprot id: A0A2U4CEH3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:NPY2R
gene id: 9739:NPY2R
uniprot id: A0A6J3RFX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9739:LOC117312418
gene id: 9739:LOC117312418
uniprot id: A0A6J3RE04
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

9739:LPAR4
gene id: 9739:LPAR4
uniprot id: A0A2U3V3Q4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9739:THUMPD3
gene id: 9739:THUMPD3
uniprot id: A0A2U4C429
uniprot id: A0A2U4C436
uniprot id: A0A2U4C457
names: Similarity
messages: Belongs to the methyltransferase superfamily.

9739:CFAP91
gene id: 9739:CFAP91
uniprot id: A0A6J3RAP5
uniprot id: A0A6J3RB15
names: Similarity
messages: Belongs to the CFAP91 family.

9739:EIF4G2
gene id: 9739:EIF4G2
uniprot id: A0A6J3RV91
uniprot id: A0A6J3RVQ6
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4G family.

9739:NCK1
gene id: 9739:NCK1
uniprot id: A0A2U3V169
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum

9739:LGSN
gene id: 9739:LGSN
uniprot id: A0A6J3S9S4
names: Similarity
messages: Belongs to the glutamine synthetase family.

9739:HADHA
gene id: 9739:HADHA
uniprot id: A0A2U4BZS8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

9739:BCAP29
gene id: 9739:BCAP29
uniprot id: A0A2U4BSK0
uniprot id: A0A2U4BSV9
uniprot id: A0A6J3RWQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays a role in the export of secreted proteins in the ER.

9739:SLC33A1
gene id: 9739:SLC33A1
uniprot id: A0A2U3V3A4
uniprot id: A0A6J3RA05
names: Subcellular Location Annotation
messages: Membrane

9739:LOC101323424
gene id: 9739:LOC101323424
uniprot id: A0A6J3RYA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H3 family.
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus

9739:HUS1
gene id: 9739:HUS1
uniprot id: A0A2U4BPN8
names: Similarity
messages: Belongs to the HUS1 family.

9739:KCTD3
gene id: 9739:KCTD3
uniprot id: A0A2U4A527
uniprot id: A0A2U4A5X2
names: Similarity
messages: Belongs to the KCTD3 family.

9739:INIP
gene id: 9739:INIP
uniprot id: A0A2U3V4Y2
uniprot id: A0A2U4C980
uniprot id: A0A2U4C985
uniprot id: A0A2U4C990
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SOSS-C family.
messages: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs).
messages: Component of the SOSS complex.
messages: Nucleus

9739:PPP2R2B
gene id: 9739:PPP2R2B
uniprot id: A0A6J3R474
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

9739:LOC101321617
gene id: 9739:LOC101321617
uniprot id: A0A6J3S9X1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Component of the small ribosomal subunit.

9739:PSPH
gene id: 9739:PSPH
uniprot id: A0A2U4A970
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

9739:SMAD1
gene id: 9739:SMAD1
uniprot id: A0A2U4AM99
uniprot id: A0A2U4AMD5
uniprot id: A0A6J3REL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

9739:ATP6V0C
gene id: 9739:ATP6V0C
uniprot id: A0A6J3Q4L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: Vacuole membrane
messages: clathrin-coated vesicle membrane
messages: synaptic vesicle membrane

9739:CCDC181
gene id: 9739:CCDC181
uniprot id: A0A2U3ZZU6
uniprot id: A0A6J3R8W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC181 family.
messages: Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids.
messages: cytoskeleton

9739:MMP8
gene id: 9739:MMP8
uniprot id: A0A2U4CG15
uniprot id: A0A6J3RTV2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

9739:VTA1
gene id: 9739:VTA1
uniprot id: A0A2U4CPN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTA1 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

9739:SLC6A2
gene id: 9739:SLC6A2
uniprot id: A0A2U4B4E8
uniprot id: A0A2U4B4F3
uniprot id: A0A2U4B4G5
uniprot id: A0A2U4B4V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

9739:KIF15
gene id: 9739:KIF15
uniprot id: A0A2U4CA66
uniprot id: A0A6J3S0T6
uniprot id: A0A6J3S101
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-12 subfamily.
messages: spindle

9739:ORAI1
gene id: 9739:ORAI1
uniprot id: A0A2U3VAN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

9739:FGFR4
gene id: 9739:FGFR4
uniprot id: A0A6J3R4K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Cell membrane
messages: Membrane

9739:ERAP1
gene id: 9739:ERAP1
uniprot id: A0A2U3V5V7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Membrane

9739:CFDP1
gene id: 9739:CFDP1
uniprot id: A0A2U4BTX4
uniprot id: A0A6J3QIU6
names: Function
names: Subcellular Location Annotation
messages: May play a role during embryogenesis.
messages: kinetochore

9739:DYRK3
gene id: 9739:DYRK3
uniprot id: A0A2U3ZZV0
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

9739:ERN2
gene id: 9739:ERN2
uniprot id: A0A2U4A9C4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:GLDN
gene id: 9739:GLDN
uniprot id: A0A2U4B1X8
uniprot id: A0A6J3QZD8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:TFCP2
gene id: 9739:TFCP2
uniprot id: A0A2U4CBI6
uniprot id: A0A2U4CBI7
uniprot id: A0A2U4CBI8
uniprot id: A0A2U4CBK4
uniprot id: A0A6J3S6F8
uniprot id: A0A6J3S6Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

9739:CLPS
gene id: 9739:CLPS
uniprot id: A0A6J3RYA0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.
messages: Enterostatin has a biological activity as a satiety signal.
messages: Forms a 1:1 stoichiometric complex with pancreatic lipase.
messages: Secreted

9739:RPS2
gene id: 9739:RPS2
uniprot id: A0A2U3VAG7
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

9739:BCLAF3
gene id: 9739:BCLAF3
uniprot id: A0A2U4AQI4
uniprot id: A0A2U4AQJ3
uniprot id: A0A2U4AQJ6
uniprot id: A0A2U4AQJ8
uniprot id: A0A2U4AQJ9
uniprot id: A0A2U4AQK0
uniprot id: A0A2U4AQY9
uniprot id: A0A6J3QVE3
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

9739:LOC117313631
gene id: 9739:LOC117313631
uniprot id: A0A6J3RXP3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9739:PSEN1
gene id: 9739:PSEN1
uniprot id: A0A2U4A8E9
uniprot id: A0A2U4A8F1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Cytoplasmic granule
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: Synapse
messages: The PAL motif is required for normal active site conformation.
messages: axon
messages: neuron projection

9739:MED6
gene id: 9739:MED6
uniprot id: A0A2U4A9X4
uniprot id: A0A6J3QWK6
uniprot id: A0A6J3QWS3
uniprot id: A0A6J3QXH4
uniprot id: A0A6J3QYF0
uniprot id: A0A6J3QYF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 6 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

9739:POMGNT1
gene id: 9739:POMGNT1
uniprot id: A0A6J3S8L6
uniprot id: A0A6J3S8M1
uniprot id: A0A6J3S8M6
uniprot id: A0A6J3S8N2
uniprot id: A0A6J3S9P0
uniprot id: A0A6J3S9Q2
uniprot id: A0A6J3S9T9
uniprot id: A0A6J3S9V3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.
messages: Membrane
messages: Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins. Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties. Is specific for alpha linked terminal mannose.
messages: The cofactor is mostly bound to the substrate.
messages: The manganese ion interacts primarily with the substrate UDP-N-acetylglucosamine.
messages: The stem domain mediates specific interaction with beta-linked N-acetylglucosamine moieties of O-glycosylated proteins. It also interacts with its product, N-acetyl-beta-D-glucosaminyl-(1->2)-O-alpha-D-mannosylprotein.

9739:DTYMK
gene id: 9739:DTYMK
uniprot id: A0A2U4B9V0
uniprot id: A0A2U4B9W0
uniprot id: A0A2U4B9Y9
uniprot id: A0A2U4BA29
uniprot id: A0A6J3RKF6
uniprot id: A0A6J3RKT2
uniprot id: A0A6J3RKU6
uniprot id: A0A6J3RLN1
uniprot id: A0A6J3RMB0
names: Similarity
messages: Belongs to the thymidylate kinase family.

9739:CAPN7
gene id: 9739:CAPN7
uniprot id: A0A2U4B9R4
uniprot id: A0A6J3RBH0
names: Similarity
messages: Belongs to the peptidase C2 family.

9739:DOK2
gene id: 9739:DOK2
uniprot id: A0A6J3RGL2
names: Similarity
messages: Belongs to the DOK family. Type A subfamily.

9739:MCM6
gene id: 9739:MCM6
uniprot id: A0A2U4AJV4
uniprot id: A0A6J3RP18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

9739:ZFP36
gene id: 9739:ZFP36
uniprot id: A0A6J3QEC9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

9739:DRAM1
gene id: 9739:DRAM1
uniprot id: A0A2U3ZYK7
uniprot id: A0A2U3ZZK4
uniprot id: A0A6J3S6J3
names: Subcellular Location Annotation
messages: Membrane

9739:FDXR
gene id: 9739:FDXR
uniprot id: A0A6J3QLA9
uniprot id: A0A6J3QLF7
uniprot id: A0A6J3QLY8
uniprot id: A0A6J3QMG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferredoxin--NADP reductase type 1 family.
messages: Mitochondrion
messages: Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver.

9739:WNT5B
gene id: 9739:WNT5B
uniprot id: A0A6J3S7X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9739:PBX4
gene id: 9739:PBX4
uniprot id: A0A6J3R5D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

9739:CYFIP2
gene id: 9739:CYFIP2
uniprot id: A0A6J3R3W7
names: Similarity
messages: Belongs to the CYFIP family.

9739:SUPT16H
gene id: 9739:SUPT16H
uniprot id: A0A2U4BC95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24 family. SPT16 subfamily.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Component of the FACT complex.
messages: Nucleus

9739:GLE1
gene id: 9739:GLE1
uniprot id: A0A6J3RJU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLE1 family.
messages: Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC).
messages: nuclear pore complex

9739:CRELD2
gene id: 9739:CRELD2
uniprot id: A0A6J3S5D8
names: Caution
names: Similarity
messages: Belongs to the CRELD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:LAMP1
gene id: 9739:LAMP1
uniprot id: A0A2U4A670
uniprot id: A0A2U4A6B1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lysosome membrane
messages: Membrane

9739:POLR2E
gene id: 9739:POLR2E
uniprot id: A0A6J3R7Q2
uniprot id: A0A6J3R7V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. Seems to be the major component in this process.
messages: Nucleus

9739:TERF2
gene id: 9739:TERF2
uniprot id: A0A2U3V434
uniprot id: A0A2U4BD67
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.
messages: Homodimer.
messages: Nucleus
messages: telomere

9739:LOXL3
gene id: 9739:LOXL3
uniprot id: A0A6J3PV98
uniprot id: A0A6J3PVA2
uniprot id: A0A6J3PVA4
uniprot id: A0A6J3PVA8
uniprot id: A0A6J3PVK0
uniprot id: A0A6J3PVK4
uniprot id: A0A6J3PVK9
uniprot id: A0A6J3PW00
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

9739:INTS10
gene id: 9739:INTS10
uniprot id: A0A6J3QQV5
uniprot id: A0A6J3QQW0
uniprot id: A0A6J3QRG5
uniprot id: A0A6J3QRG7
uniprot id: A0A6J3QRH9
uniprot id: A0A6J3QS11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 10 family.
messages: Nucleus

9739:GIMAP4
gene id: 9739:GIMAP4
uniprot id: A0A2U4B8F1
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

9739:LOC101336277
gene id: 9739:LOC101336277
uniprot id: A0A2U4CQ16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts both as a regulator of telomere function and as a transcription regulator. Involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). Does not bind DNA directly: recruited to telomeric double-stranded 5'-TTAGGG-3' repeats via its interaction with terf2. Independently of its function in telomeres, also acts as a transcription regulator: recruited to extratelomeric 5'-TTAGGG-3' sites via its association with terf2 or other factors, and regulates gene expression.
messages: Belongs to the RAP1 family.
messages: Homodimer.
messages: Nucleus
messages: telomere

9739:LOC117313237
gene id: 9739:LOC117313237
uniprot id: A0A6J3RRE6
uniprot id: A0A6J3RRL9
uniprot id: A0A6J3RS09
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

9739:LOC109551256
gene id: 9739:LOC109551256
uniprot id: A0A6J3QT81
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

9739:FAM167A
gene id: 9739:FAM167A
uniprot id: A0A2U4B453
names: Similarity
messages: Belongs to the FAM167 (SEC) family.

9739:LOC101333487
gene id: 9739:LOC101333487
uniprot id: A0A2U3V4I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYF2 family.
messages: Involved in pre-mRNA splicing.
messages: May be part of a spliceosome complex.
messages: Nucleus

9739:MRPS18B
gene id: 9739:MRPS18B
uniprot id: A0A2U3V6I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bS18 family. Mitochondrion-specific ribosomal protein mS40 subfamily.
messages: Mitochondrion

9739:CDKN1A
gene id: 9739:CDKN1A
uniprot id: A0A6J3S050
names: Similarity
messages: Belongs to the CDI family.

9739:LOC117312611
gene id: 9739:LOC117312611
uniprot id: A0A6J3RIV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

9739:COQ9
gene id: 9739:COQ9
uniprot id: A0A2U4BDN3
uniprot id: A0A6J3QFQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ9 family.
messages: Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
messages: Mitochondrion

9739:FARSB
gene id: 9739:FARSB
uniprot id: A0A2U4ADK1
uniprot id: A0A2U4AE39
names: Similarity
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.

9739:TMEM120B
gene id: 9739:TMEM120B
uniprot id: A0A6J3PRD0
uniprot id: A0A6J3PRW5
uniprot id: A0A6J3PS01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM120 family.
messages: Membrane
messages: Nucleus inner membrane

9739:EIF3D
gene id: 9739:EIF3D
uniprot id: A0A2U3ZZS8
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit D family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3.
messages: Cytoplasm
messages: Phosphorylated upon DNA damage, probably by ATM or ATR.
messages: The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. In the eIF-3 complex, EIF3D specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.

9739:FGF6
gene id: 9739:FGF6
uniprot id: A0A2U3V8R4
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9739:LOC101339512
gene id: 9739:LOC101339512
uniprot id: A0A6J3RCC2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit J family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. This subunit binds directly within the mRNA entry channel of the 40S ribosome to the aminoacyl (A) site. It may regulate the interaction between the 43S PIC and mRNA.
messages: Cytoplasm
messages: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.

9739:MDGA2
gene id: 9739:MDGA2
uniprot id: A0A6J3QYX5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9739:TJP2
gene id: 9739:TJP2
uniprot id: A0A2U4BAQ2
uniprot id: A0A2U4BAQ3
uniprot id: A0A2U4BAQ6
uniprot id: A0A2U4BB34
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: tight junction

9739:LOC101326830
gene id: 9739:LOC101326830
uniprot id: A0A2U3V5F5
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

9739:GNL2
gene id: 9739:GNL2
uniprot id: A0A2U4BKC7
uniprot id: A0A2U4BKG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
messages: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.
messages: nucleolus

9739:NFXL1
gene id: 9739:NFXL1
uniprot id: A0A2U4AS40
uniprot id: A0A2U4AS51
uniprot id: A0A2U4AS65
names: Similarity
messages: Belongs to the NFX1 family.

9739:TMEM50A
gene id: 9739:TMEM50A
uniprot id: A0A2U4BLC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

9739:AQP3
gene id: 9739:AQP3
uniprot id: A0A6J3RGZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

9739:STAB2
gene id: 9739:STAB2
uniprot id: A0A2U4CR19
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:TBX6
gene id: 9739:TBX6
uniprot id: A0A6J3Q2P6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9739:ARID1A
gene id: 9739:ARID1A
uniprot id: A0A6J3Q1M8
uniprot id: A0A6J3Q1Q1
uniprot id: A0A6J3Q1U1
uniprot id: A0A6J3Q257
names: Subcellular Location Annotation
messages: Nucleus

9739:CCDC34
gene id: 9739:CCDC34
uniprot id: A0A2U4CEV9
names: Subcellular Location Annotation
messages: flagellum

9739:C6H9orf78
gene id: 9739:C6H9orf78
uniprot id: A0A2U4A471
uniprot id: A0A2U4A510
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TLS1 family.
messages: Nucleus

9739:MFSD6
gene id: 9739:MFSD6
uniprot id: A0A2U4B1G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. MFSD6 family.
messages: Membrane

9739:LOC101329612
gene id: 9739:LOC101329612
uniprot id: A0A6J3SAR1
names: Similarity
messages: Belongs to the FAM10 family.

9739:PLA2G4E
gene id: 9739:PLA2G4E
uniprot id: A0A6J3QZ05
uniprot id: A0A6J3QZY8
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

9739:CCL21
gene id: 9739:CCL21
uniprot id: A0A2U3V054
uniprot id: A0A2U4BS61
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.

9739:DDIT4
gene id: 9739:DDIT4
uniprot id: A0A2U3V4Z8
names: Similarity
messages: Belongs to the DDIT4 family.

9739:C8H11orf54
gene id: 9739:C8H11orf54
uniprot id: A0A2U4AEA6
uniprot id: A0A2U4AES1
uniprot id: A0A6J3Q850
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Exhibits ester hydrolase activity on the substrate p-nitrophenyl acetate.
messages: Monomer.
messages: Nucleus

9739:TARS1
gene id: 9739:TARS1
uniprot id: A0A2U4AY52
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

9739:ATRN
gene id: 9739:ATRN
uniprot id: A0A2U4CLB3
uniprot id: A0A2U4CLB4
uniprot id: A0A2U4CLI5
uniprot id: A0A6J3Q2E6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:RBM3
gene id: 9739:RBM3
uniprot id: A0A6J3QUJ7
uniprot id: A0A6J3QVJ8
names: Subcellular Location Annotation
messages: Cytoplasm

9739:LOC101323276
gene id: 9739:LOC101323276
uniprot id: A0A2U4C080
uniprot id: A0A2U4C086
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

9739:LYPLAL1
gene id: 9739:LYPLAL1
uniprot id: A0A2U4A573
uniprot id: A0A2U4A580
uniprot id: A0A2U4A610
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

9739:CHMP4B
gene id: 9739:CHMP4B
uniprot id: A0A6J3Q3G7
names: Similarity
messages: Belongs to the SNF7 family.

9739:CERS3
gene id: 9739:CERS3
uniprot id: A0A2U4C7I4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

9739:GORASP2
gene id: 9739:GORASP2
uniprot id: A0A2U3V8J1
uniprot id: A0A2U4AC16
uniprot id: A0A2U4ACJ3
names: Similarity
messages: Belongs to the GORASP family.

9739:VAX2
gene id: 9739:VAX2
uniprot id: A0A6J3PWL6
names: Subcellular Location Annotation
messages: Nucleus

9739:LOC101326628
gene id: 9739:LOC101326628
uniprot id: A0A6J3RVY9
names: Similarity
messages: Belongs to the proteasome subunit p27 family.

9739:PRDM1
gene id: 9739:PRDM1
uniprot id: A0A2U3V8E9
uniprot id: A0A2U3V8T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Interacts with PRMT5. Interacts with FBXO10. Interacts with FBXO11.
messages: Nucleus
messages: Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection. Binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells. Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions.

9739:HMCN1
gene id: 9739:HMCN1
uniprot id: A0A6J3R479
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:SNTG1
gene id: 9739:SNTG1
uniprot id: A0A2U4AJ38
uniprot id: A0A6J3Q8U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: cytoskeleton

9739:RYR2
gene id: 9739:RYR2
uniprot id: A0A6J3Q5G5
names: Subcellular Location Annotation
messages: Membrane
messages: Sarcoplasmic reticulum membrane

9739:LOC117310177
gene id: 9739:LOC117310177
uniprot id: A0A6J3QRQ0
names: Similarity
messages: Belongs to the NXF family.

9739:TM6SF2
gene id: 9739:TM6SF2
uniprot id: A0A6J3R5B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TM6SF family.
messages: Membrane

9739:RNF10
gene id: 9739:RNF10
uniprot id: A0A2U4CK95
uniprot id: A0A2U4CK96
uniprot id: A0A2U4CKG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNF10 family.
messages: Cytoplasm

9739:GUCY1A1
gene id: 9739:GUCY1A1
uniprot id: A0A2U4ALR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

9739:ACP7
gene id: 9739:ACP7
uniprot id: A0A6J3QBX8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.

9739:NBN
gene id: 9739:NBN
uniprot id: A0A2U3V5A9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.
messages: Component of the MRN complex.
messages: Nucleus
messages: telomere

9739:DUSP4
gene id: 9739:DUSP4
uniprot id: A0A2U3UYV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

9739:DPM1
gene id: 9739:DPM1
uniprot id: A0A2U3V612
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum
messages: Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins; catalytic subunit of the dolichol-phosphate mannose (DPM) synthase complex.

9739:CA8
gene id: 9739:CA8
uniprot id: A0A2U4AIN6
uniprot id: A0A6J3QA46
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

9739:VAMP8
gene id: 9739:VAMP8
uniprot id: A0A2U3V0H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

9739:TMEM255A
gene id: 9739:TMEM255A
uniprot id: A0A2U4CHR2
uniprot id: A0A2U4CHR4
uniprot id: A0A2U4CHS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM255 family.
messages: Membrane

9739:SGO1
gene id: 9739:SGO1
uniprot id: A0A2U4BA96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

9739:RBM5
gene id: 9739:RBM5
uniprot id: A0A2U4B237
uniprot id: A0A2U4B241
uniprot id: A0A2U4B245
uniprot id: A0A2U4B281
uniprot id: A0A2U4B2H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RBM5/RBM10 family.
messages: Nucleus

9739:SEPTIN6
gene id: 9739:SEPTIN6
uniprot id: A0A2U4CI21
uniprot id: A0A6J3QR95
uniprot id: A0A6J3QR99
uniprot id: A0A6J3QRA3
uniprot id: A0A6J3QRL8
uniprot id: A0A6J3QRM3
uniprot id: A0A6J3QRM7
uniprot id: A0A6J3QS20
uniprot id: A0A6J3QS28
uniprot id: A0A6J3QS33
uniprot id: A0A6J3QS38
uniprot id: A0A6J3QSM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

9739:HPS5
gene id: 9739:HPS5
uniprot id: A0A2U4CE67
uniprot id: A0A2U4CE69
uniprot id: A0A6J3RVE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPS5 family.
messages: Component of the biogenesis of lysosome-related organelles complex-2 (or BLOC2) composed of HPS3, HPS5 and HPS6.
messages: May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.
messages: cytosol

9739:LOC101320435
gene id: 9739:LOC101320435
uniprot id: A0A6J3R9M3
names: Similarity
messages: Belongs to the TMA7 family.

9739:MRPL4
gene id: 9739:MRPL4
uniprot id: A0A6J3R726
uniprot id: A0A6J3R8V1
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

9739:LOC101323815
gene id: 9739:LOC101323815
uniprot id: A0A2U3V3J3
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

9739:NADSYN1
gene id: 9739:NADSYN1
uniprot id: A0A6J3RRY6
uniprot id: A0A6J3RSC9
names: Similarity
names: Subunit
messages: Homohexamer.
messages: In the C-terminal section; belongs to the NAD synthetase family.

9739:GSX1
gene id: 9739:GSX1
uniprot id: A0A6J3QBW9
names: Subcellular Location Annotation
messages: Nucleus

9739:LOC117308154
gene id: 9739:LOC117308154
uniprot id: A0A6J3Q166
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

9739:IFITM5
gene id: 9739:IFITM5
uniprot id: A0A6J3RSM1
names: Similarity
messages: Belongs to the CD225/Dispanin family.

9739:ASPHD1
gene id: 9739:ASPHD1
uniprot id: A0A6J3Q017
names: Similarity
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.

9739:LOC117314246
gene id: 9739:LOC117314246
uniprot id: A0A6J3S7Y7
names: Similarity
messages: Belongs to the protein kinase superfamily.

9739:TRPM1
gene id: 9739:TRPM1
uniprot id: A0A2U4C7J0
uniprot id: A0A2U4C7J5
uniprot id: A0A2U4C7J6
uniprot id: A0A2U4C7K3
uniprot id: A0A2U4C7K8
uniprot id: A0A2U4C7T5
uniprot id: A0A6J3R0Y5
uniprot id: A0A6J3R282
names: Subcellular Location Annotation
messages: Membrane

9739:IPO8
gene id: 9739:IPO8
uniprot id: A0A2U4BDL5
uniprot id: A0A2U4BDM0
uniprot id: A0A2U4BDN6
names: Subcellular Location Annotation
messages: Cytoplasm

9739:KEAP1
gene id: 9739:KEAP1
uniprot id: A0A2U4B5X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KEAP1 family.
messages: Cytoplasm
messages: Nucleus

9739:XPR1
gene id: 9739:XPR1
uniprot id: A0A2U3ZZI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYG1 (TC 2.A.94) family.
messages: Membrane

9739:VPS8
gene id: 9739:VPS8
uniprot id: A0A2U4C893
uniprot id: A0A2U4C897
names: Similarity
messages: Belongs to the VPS8 family.

9739:CAMK2N2
gene id: 9739:CAMK2N2
uniprot id: A0A6J3RAF5
names: Similarity
messages: Belongs to the CAMK2N family.

9739:ERC1
gene id: 9739:ERC1
uniprot id: A0A2U4AKE8
uniprot id: A0A2U4AKF2
uniprot id: A0A2U4AKF3
uniprot id: A0A2U4AKF4
uniprot id: A0A2U4AKF9
uniprot id: A0A2U4AKJ3
uniprot id: A0A2U4AKJ8
uniprot id: A0A2U4AKW8
uniprot id: A0A6J3S9I8
names: Subcellular Location Annotation
messages: Cytoplasm

9739:SLC37A1
gene id: 9739:SLC37A1
uniprot id: A0A6J3RB03
uniprot id: A0A6J3RB08
uniprot id: A0A6J3RB79
uniprot id: A0A6J3RB84
uniprot id: A0A6J3RB89
uniprot id: A0A6J3RBQ3
uniprot id: A0A6J3RBX9
uniprot id: A0A6J3RBZ1
uniprot id: A0A6J3RC00
uniprot id: A0A6J3RDN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Inorganic phosphate and glucose-6-phosphate antiporter. May transport cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocate inorganic phosphate into the opposite direction. Independent of a lumenal glucose-6-phosphatase. May not play a role in homeostatic regulation of blood glucose levels.
messages: Membrane

9739:WEE1
gene id: 9739:WEE1
uniprot id: A0A2U4CF00
uniprot id: A0A2U4CF06
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
messages: Binds 2 magnesium ions per subunit.
messages: Nucleus

9739:LOC117313338
gene id: 9739:LOC117313338
uniprot id: A0A6J3RT50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPEG1 family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

9739:CNN2
gene id: 9739:CNN2
uniprot id: A0A6J3R7W2
uniprot id: A0A6J3R8A8
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

9739:CACNB3
gene id: 9739:CACNB3
uniprot id: A0A6J3S6S1
uniprot id: A0A6J3S7A4
uniprot id: A0A6J3S8I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: Cytoplasm

9739:FAM83F
gene id: 9739:FAM83F
uniprot id: A0A2U4C1C9
uniprot id: A0A2U4C1E4
names: Similarity
messages: Belongs to the FAM83 family.

9739:CAMK2N1
gene id: 9739:CAMK2N1
uniprot id: A0A2U3UYP5
names: Similarity
messages: Belongs to the CAMK2N family.

9739:TTC25
gene id: 9739:TTC25
uniprot id: A0A2U4BPC7
names: Subcellular Location Annotation
messages: cilium axoneme

9739:ATP8B4
gene id: 9739:ATP8B4
uniprot id: A0A2U4AV63
uniprot id: A0A6J3QYG6
uniprot id: A0A6J3QYH1
uniprot id: A0A6J3QYS9
uniprot id: A0A6J3QZ30
uniprot id: A0A6J3QZD2
uniprot id: A0A6J3QZD5
uniprot id: A0A6J3R0B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

9739:TRRAP
gene id: 9739:TRRAP
uniprot id: A0A6J3Q249
uniprot id: A0A6J3Q252
uniprot id: A0A6J3Q255
uniprot id: A0A6J3Q259
uniprot id: A0A6J3Q260
uniprot id: A0A6J3Q265
uniprot id: A0A6J3Q2B1
uniprot id: A0A6J3Q2C7
uniprot id: A0A6J3Q2D6
uniprot id: A0A6J3Q2E2
uniprot id: A0A6J3Q2T6
uniprot id: A0A6J3Q2U4
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. TRA1 subfamily.

9739:LOC101327326
gene id: 9739:LOC101327326
uniprot id: A0A2U4C3Z6
uniprot id: A0A2U4C3Z7
uniprot id: A0A2U4C417
uniprot id: A0A2U4C460
uniprot id: A0A6J3S3C2
uniprot id: A0A6J3S4A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.
messages: Cytoplasm
messages: Heterodimer with other nuclear receptors.
messages: Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. May play a role in the regulation of circadian rhythm.
messages: Nucleus

9739:CCNT1
gene id: 9739:CCNT1
uniprot id: A0A2U4BA31
uniprot id: A0A2U4BA70
names: Similarity
messages: Belongs to the cyclin family.

9739:NHSL1
gene id: 9739:NHSL1
uniprot id: A0A2U4CNJ6
uniprot id: A0A2U4CNJ9
uniprot id: A0A2U4CNL1
uniprot id: A0A6J3SAT5
names: Similarity
messages: Belongs to the NHS family.

9739:PDCL3
gene id: 9739:PDCL3
uniprot id: A0A2U3V3S4
uniprot id: A0A2U4B0Z5
names: Similarity
messages: Belongs to the phosducin family.

9739:OLFML2A
gene id: 9739:OLFML2A
uniprot id: A0A6J3RI96
uniprot id: A0A6J3RIH4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:SHMT1
gene id: 9739:SHMT1
uniprot id: A0A6J3QKS3
uniprot id: A0A6J3QKW5
uniprot id: A0A6J3QKX1
uniprot id: A0A6J3QLH4
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

9739:LOC117312654
gene id: 9739:LOC117312654
uniprot id: A0A6J3RJL7
names: Subcellular Location Annotation
messages: Nucleus

9739:DYNC1I2
gene id: 9739:DYNC1I2
uniprot id: A0A6J3RMK6
uniprot id: A0A6J3RN16
uniprot id: A0A6J3RNI0
names: Similarity
messages: Belongs to the dynein intermediate chain family.

9739:HEATR5B
gene id: 9739:HEATR5B
uniprot id: A0A2U4BYY4
uniprot id: A0A2U4BYY8
uniprot id: A0A2U4BYZ3
uniprot id: A0A2U4BZ28
names: Similarity
messages: Belongs to the HEATR5 family.

9739:RNF168
gene id: 9739:RNF168
uniprot id: A0A2U4AAH5
uniprot id: A0A2U4AAJ6
uniprot id: A0A6J3R9V1
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: According to a well-established model, RNF168 cannot initiate H2A 'Lys-63'-linked ubiquitination and is recruited following RNF8-dependent histone ubiquitination to amplify H2A 'Lys-63'-linked ubiquitination. However, other data suggest that RNF168 is the priming ubiquitin ligase by mediating monoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histone H2A (H2AK13Ub and H2AK15Ub respectively). These data suggest that RNF168 might be recruited to DSBs sites in a RNF8-dependent manner by binding to non-histone proteins ubiquitinated via 'Lys-63'-linked and initiates monoubiquitination of H2A, which is then amplified by RNF8. Additional evidences are however required to confirm these data.
messages: Belongs to the RNF168 family.
messages: E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recruited at DNA interstrand cross-links (ICLs) sites and promotes accumulation of 'Lys-63'-linked ubiquitination of histones H2A and H2AX, leading to recruitment of FAAP20 and Fanconi anemia (FA) complex, followed by interstrand cross-link repair. H2A ubiquitination also mediates the ATM-dependent transcriptional silencing at regions flanking DSBs in cis, a mechanism to avoid collision between transcription and repair intermediates. Also involved in class switch recombination in immune system, via its role in regulation of DSBs repair. Following DNA damage, promotes the ubiquitination and degradation of JMJD2A/KDM4A in collaboration with RNF8, leading to unmask H4K20me2 mark and promote the recruitment of TP53BP1 at DNA damage sites. Not able to initiate 'Lys-63'-linked ubiquitination in vitro; possibly due to partial occlusion of the UBE2N/UBC13-binding region. Catalyzes monoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histone H2A (H2AK13Ub and H2AK15Ub, respectively).
messages: Monomer. Interacts with UBE2N/UBC13.
messages: Nucleus
messages: Sumoylated with SUMO1 by PIAS4 in response to double-strand breaks (DSBs).
messages: The MIU motif (motif interacting with ubiquitin) mediates the interaction with both 'Lys-48'- and 'Lys-63'-linked ubiquitin chains. The UMI motif mediates interaction with ubiquitin with a preference for 'Lys-63'-linked ubiquitin. The specificity for different types of ubiquitin is mediated by juxtaposition of ubiquitin-binding motifs (MIU and UMI motifs) with LR motifs (LRMs).
messages: Ubiquitinated.

9739:LOC101319291
gene id: 9739:LOC101319291
uniprot id: A0A6J3Q4S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

9739:MAMDC4
gene id: 9739:MAMDC4
uniprot id: A0A6J3RKS4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:SLC25A23
gene id: 9739:SLC25A23
uniprot id: A0A6J3R6K7
uniprot id: A0A6J3R6L0
uniprot id: A0A6J3R6Q2
uniprot id: A0A6J3R753
uniprot id: A0A6J3R7K4
uniprot id: A0A6J3R9E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

9739:LOC101330606
gene id: 9739:LOC101330606
uniprot id: A0A2U4BML3
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

9739:NFYB
gene id: 9739:NFYB
uniprot id: A0A2U3VA01
uniprot id: A0A2U3ZZ83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NFYB/HAP3 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.
messages: Heterotrimeric transcription factor composed of three components, NF-YA, NF-YB and NF-YC. NF-YB and NF-YC must interact and dimerize for NF-YA association and DNA binding. Interacts with C1QBP.

9739:SDC3
gene id: 9739:SDC3
uniprot id: A0A6J3PYK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

9739:GPR34
gene id: 9739:GPR34
uniprot id: A0A2U4C168
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Orphan receptor.

9739:GALR1
gene id: 9739:GALR1
uniprot id: A0A2U3V8M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

9739:THBS2
gene id: 9739:THBS2
uniprot id: A0A2U3V6H1
uniprot id: A0A6J3PQQ2
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:SUGT1
gene id: 9739:SUGT1
uniprot id: A0A2U4BFL8
names: Similarity
messages: Belongs to the SGT1 family.

9739:NNT
gene id: 9739:NNT
uniprot id: A0A2U4AXF3
uniprot id: A0A2U4AXU1
names: Similarity
messages: In the N-terminal section; belongs to the AlaDH/PNT family.

9739:BSX
gene id: 9739:BSX
uniprot id: A0A2U4BVR5
names: Subcellular Location Annotation
messages: Nucleus

9739:LOC101316757
gene id: 9739:LOC101316757
uniprot id: A0A6J3RBR7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

9739:AKAP9
gene id: 9739:AKAP9
uniprot id: A0A2U4ANM3
uniprot id: A0A2U4ANM8
uniprot id: A0A2U4ANR0
uniprot id: A0A2U4ANS3
uniprot id: A0A2U4ANT6
uniprot id: A0A2U4ANV0
uniprot id: A0A2U4ANV1
uniprot id: A0A2U4ANW3
uniprot id: A0A2U4AP30
uniprot id: A0A2U4AP42
uniprot id: A0A2U4AP80
uniprot id: A0A6J3RWN5
uniprot id: A0A6J3RWQ5
names: Subcellular Location Annotation
messages: centrosome

9739:ANKRD13B
gene id: 9739:ANKRD13B
uniprot id: A0A2U4ANJ3
uniprot id: A0A2U4ANK2
uniprot id: A0A6J3QMZ7
uniprot id: A0A6J3QNI5
uniprot id: A0A6J3QNJ3
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

9739:LOC101329815
gene id: 9739:LOC101329815
uniprot id: A0A6J3S9X9
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

9739:SOHLH1
gene id: 9739:SOHLH1
uniprot id: A0A6J3RKL7
names: Subcellular Location Annotation
messages: Nucleus

9739:PKD2L2
gene id: 9739:PKD2L2
uniprot id: A0A2U4AGD4
uniprot id: A0A2U4AGE3
uniprot id: A0A2U4AGK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Membrane
messages: cilium membrane

9739:DLC1
gene id: 9739:DLC1
uniprot id: A0A2U4A875
uniprot id: A0A6J3QRL7
names: Subcellular Location Annotation
messages: Cytoplasm

9739:LOC101324512
gene id: 9739:LOC101324512
uniprot id: A0A2U3VAS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCTS1 family.
messages: Cytoplasm

9739:CHAC2
gene id: 9739:CHAC2
uniprot id: A0A2U4BYB4
uniprot id: A0A2U4BYB8
uniprot id: A0A2U4BYG5
uniprot id: A0A2U4BYG9
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

9739:EPYC
gene id: 9739:EPYC
uniprot id: A0A2U4CQJ5
names: Similarity
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.

9739:CA3
gene id: 9739:CA3
uniprot id: A0A2U4AM45
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

9739:PKIA
gene id: 9739:PKIA
uniprot id: A0A6J3Q9C5
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

9739:STX1B
gene id: 9739:STX1B
uniprot id: A0A6J3Q254
names: Similarity
messages: Belongs to the syntaxin family.

9739:CDC42EP3
gene id: 9739:CDC42EP3
uniprot id: A0A2U4BZW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

9739:CREG2
gene id: 9739:CREG2
uniprot id: A0A2U3V620
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREG family.
messages: Secreted

9739:GPM6A
gene id: 9739:GPM6A
uniprot id: A0A2U4A854
uniprot id: A0A6J3QQN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

9739:LOC109551478
gene id: 9739:LOC109551478
uniprot id: A0A2U4C4M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H3 family.
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus

9739:MRPS33
gene id: 9739:MRPS33
uniprot id: A0A2U3V5C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS33 family.
messages: Mitochondrion

9739:KCNK6
gene id: 9739:KCNK6
uniprot id: A0A6J3QEK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

9739:FAM227B
gene id: 9739:FAM227B
uniprot id: A0A6J3QZ24
names: Similarity
messages: Belongs to the FAM227 family.

9739:HNRNPK
gene id: 9739:HNRNPK
uniprot id: A0A2U4BRT9
uniprot id: A0A2U4BS49
uniprot id: A0A6J3RH23
uniprot id: A0A6J3RH28
names: Subcellular Location Annotation
messages: Cytoplasm
messages: nucleoplasm
messages: podosome

9739:LOC101335595
gene id: 9739:LOC101335595
uniprot id: A0A2U3V657
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm

9739:AMIGO3
gene id: 9739:AMIGO3
uniprot id: A0A2U4B235
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. AMIGO family.
messages: Membrane

9739:NKAIN2
gene id: 9739:NKAIN2
uniprot id: A0A2U4CNI7
uniprot id: A0A2U4CNI8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:UROD
gene id: 9739:UROD
uniprot id: A0A6J3S916
uniprot id: A0A6J3SAC6
names: Similarity
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Homodimer.

9739:LOC117312600
gene id: 9739:LOC117312600
uniprot id: A0A6J3RGJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

9739:SLC26A8
gene id: 9739:SLC26A8
uniprot id: A0A6J3S046
uniprot id: A0A6J3S062
uniprot id: A0A6J3S0B2
uniprot id: A0A6J3S162
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:MMP20
gene id: 9739:MMP20
uniprot id: A0A2U4CG01
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

9739:GPSM1
gene id: 9739:GPSM1
uniprot id: A0A6J3RJZ6
uniprot id: A0A6J3RLP1
names: Similarity
messages: Belongs to the GPSM family.

9739:LOC101321495
gene id: 9739:LOC101321495
uniprot id: A0A2U3V1Q4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9739:FMR1
gene id: 9739:FMR1
uniprot id: A0A2U4BNM2
uniprot id: A0A2U4BNM4
uniprot id: A0A2U4BNM7
uniprot id: A0A2U4BNN0
uniprot id: A0A2U4BNN4
uniprot id: A0A2U4BNN8
uniprot id: A0A2U4BNT2
uniprot id: A0A2U4BNT7
uniprot id: A0A2U4BNU2
uniprot id: A0A2U4BNZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMR1 family.
messages: Cell membrane
messages: Cytoplasmic ribonucleoprotein granule
messages: Membrane
messages: Perikaryon
messages: Presynaptic cell membrane
messages: Stress granule
messages: Synaptic cell membrane
messages: axon
messages: centromere
messages: dendrite
messages: dendritic spine
messages: filopodium tip
messages: growth cone
messages: neuron projection
messages: nucleolus
messages: perinuclear region
messages: synaptosome

9739:TMTC2
gene id: 9739:TMTC2
uniprot id: A0A2U3ZZW6
uniprot id: A0A6J3S5P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

9739:METTL15
gene id: 9739:METTL15
uniprot id: A0A6J3RVE4
uniprot id: A0A6J3RVE9
uniprot id: A0A6J3RVJ1
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmH family.

9739:MRPS21
gene id: 9739:MRPS21
uniprot id: A0A2U3V6F4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

9739:CCDC25
gene id: 9739:CCDC25
uniprot id: A0A2U3V379
uniprot id: A0A6J3RFY0
uniprot id: A0A6J3RHQ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CCDC25 family.
messages: Cell membrane
messages: Endomembrane system
messages: Interacts (via cytoplasmic region) with ILK.

9739:GON4L
gene id: 9739:GON4L
uniprot id: A0A2U4B734
uniprot id: A0A2U4B747
uniprot id: A0A2U4B749
uniprot id: A0A2U4B774
uniprot id: A0A2U4B780
uniprot id: A0A2U4B7D0
uniprot id: A0A2U4B7L4
uniprot id: A0A2U4B7N0
names: Subcellular Location Annotation
messages: Nucleus

9739:NOL6
gene id: 9739:NOL6
uniprot id: A0A6J3RGH4
uniprot id: A0A6J3RGY5
uniprot id: A0A6J3RHB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAP family.
messages: Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
messages: nucleolus

9739:BAIAP2
gene id: 9739:BAIAP2
uniprot id: A0A6J3QMN4
uniprot id: A0A6J3QMT2
uniprot id: A0A6J3QMT7
uniprot id: A0A6J3QN85
uniprot id: A0A6J3QN88
names: Function
names: Subcellular Location Annotation
messages: Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions.
messages: Membrane
messages: cytoskeleton
messages: filopodium
messages: ruffle

9739:TMPRSS7
gene id: 9739:TMPRSS7
uniprot id: A0A2U4AD11
uniprot id: A0A2U4ADL9
uniprot id: A0A6J3RAT3
uniprot id: A0A6J3RB59
uniprot id: A0A6J3RCW0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:EVL
gene id: 9739:EVL
uniprot id: A0A6J3QWH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ena/VASP family.
messages: Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration.
messages: cytoskeleton

9739:MEMO1
gene id: 9739:MEMO1
uniprot id: A0A2U4BZD4
uniprot id: A0A2U4BZD9
uniprot id: A0A6J3PX43
uniprot id: A0A6J3PXA4
uniprot id: A0A6J3PXD6
names: Similarity
messages: Belongs to the MEMO1 family.

9739:PSMA3
gene id: 9739:PSMA3
uniprot id: A0A2U4ADF1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

9739:REV3L
gene id: 9739:REV3L
uniprot id: A0A2U4AW02
uniprot id: A0A2U4AW05
uniprot id: A0A2U4AW21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

9739:PHF20L1
gene id: 9739:PHF20L1
uniprot id: A0A2U4B2U2
uniprot id: A0A6J3Q9S9
uniprot id: A0A6J3Q9T1
uniprot id: A0A6J3Q9Y1
uniprot id: A0A6J3QAC3
uniprot id: A0A6J3QAC8
uniprot id: A0A6J3QAJ2
uniprot id: A0A6J3QAJ7
uniprot id: A0A6J3QAN8
uniprot id: A0A6J3QAP2
uniprot id: A0A6J3QAP7
names: Subcellular Location Annotation
messages: Nucleus

9739:MTFP1
gene id: 9739:MTFP1
uniprot id: A0A6J3PV04
names: Similarity
messages: Belongs to the MTFP1 family.

9739:KCNJ6
gene id: 9739:KCNJ6
uniprot id: A0A2U4AA11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ6 subfamily.
messages: Membrane

9739:CCNK
gene id: 9739:CCNK
uniprot id: A0A6J3QW33
uniprot id: A0A6J3QWI9
names: Similarity
messages: Belongs to the cyclin family.

9739:EEF1AKMT1
gene id: 9739:EEF1AKMT1
uniprot id: A0A6J3QA61
uniprot id: A0A6J3QAC0
uniprot id: A0A6J3QAS0
uniprot id: A0A6J3QB38
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
messages: Cytoplasm
messages: Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'.
messages: Was originally thought to be an N(6)-adenine-specific DNA methyltransferase based on primary sequence and predicted secondary structure.

9739:GSX2
gene id: 9739:GSX2
uniprot id: A0A2U4ARK9
names: Subcellular Location Annotation
messages: Nucleus

9739:SAR1A
gene id: 9739:SAR1A
uniprot id: A0A2U4BES3
names: Similarity
messages: Belongs to the small GTPase superfamily. SAR1 family.

9739:ANAPC13
gene id: 9739:ANAPC13
uniprot id: A0A2U3V9G5
names: Function
names: Similarity
messages: Belongs to the APC13 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

9739:WNK3
gene id: 9739:WNK3
uniprot id: A0A2U4C0Y8
uniprot id: A0A2U4C127
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

9739:DGKK
gene id: 9739:DGKK
uniprot id: A0A6J3QTT6
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

9739:DYM
gene id: 9739:DYM
uniprot id: A0A2U4BHD3
names: Similarity
messages: Belongs to the dymeclin family.

9739:LOC117312419
gene id: 9739:LOC117312419
uniprot id: A0A6J3RE28
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.

9739:ACKR4
gene id: 9739:ACKR4
uniprot id: A0A2U4B999
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9739:LOC101338991
gene id: 9739:LOC101338991
uniprot id: A0A6J3QYP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DUOXA family.
messages: Membrane

9739:GDF5
gene id: 9739:GDF5
uniprot id: A0A2U3V0D0
names: Similarity
messages: Belongs to the TGF-beta family.

9739:LOC117310152
gene id: 9739:LOC117310152
uniprot id: A0A6J3QSB0
names: Similarity
messages: Belongs to the PIH1 family.

9739:SYNPR
gene id: 9739:SYNPR
uniprot id: A0A2U4CCV7
uniprot id: A0A2U4CCW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

9739:ABCD4
gene id: 9739:ABCD4
uniprot id: A0A6J3QWF4
uniprot id: A0A6J3QWP7
uniprot id: A0A6J3QY38
names: Subcellular Location Annotation
messages: Membrane

9739:ARL17A
gene id: 9739:ARL17A
uniprot id: A0A2U4C3H6
uniprot id: A0A2U4C3I3
uniprot id: A0A2U4C3J2
uniprot id: A0A2U4C3Q0
uniprot id: A0A6J3QIU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

9739:MRPL23
gene id: 9739:MRPL23
uniprot id: A0A6J3RRV8
uniprot id: A0A6J3RS67
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

9739:POLR2H
gene id: 9739:POLR2H
uniprot id: A0A2U3V585
uniprot id: A0A2U4C8U3
uniprot id: A0A6J3R9M5
names: Function
names: Similarity
messages: Belongs to the eukaryotic RPB8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.

9739:SEC13
gene id: 9739:SEC13
uniprot id: A0A2U4C3Y8
uniprot id: A0A6J3S3A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Lysosome membrane

9739:LOC101321433
gene id: 9739:LOC101321433
uniprot id: A0A6J3RUE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

9739:ATAT1
gene id: 9739:ATAT1
uniprot id: A0A6J3RZ11
uniprot id: A0A6J3RZ33
uniprot id: A0A6J3RZ37
uniprot id: A0A6J3RZ49
uniprot id: A0A6J3RZ54
uniprot id: A0A6J3RZB0
uniprot id: A0A6J3RZB7
uniprot id: A0A6J3S002
uniprot id: A0A6J3S007
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Autoacetylation strongly increases tubulin acetylation.
messages: Belongs to the acetyltransferase ATAT1 family.
messages: Component of the BBSome complex. Interacts with AP2 alpha-adaptins, including AP2A2, but not with AP1 gamma-adaptin (AP1G1/AP1G2); this interaction is required for efficient alpha-tubulin acetylation, hence clathrin-coated pits are sites of microtubule acetylation.
messages: Cytoplasm
messages: Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. Required for normal sperm flagellar function. Promotes directional cell locomotion and chemotaxis, through AP2A2-dependent acetylation of alpha-tubulin at clathrin-coated pits that are concentrated at the leading edge of migrating cells. May facilitate primary cilium assembly.
messages: axon
messages: clathrin-coated pit
messages: cytoskeleton
messages: focal adhesion
messages: spindle

9739:GPX3
gene id: 9739:GPX3
uniprot id: A0A6J3R3U0
uniprot id: A0A6J3R492
uniprot id: A0A6J3R605
names: Similarity
messages: Belongs to the glutathione peroxidase family.

9739:ANO3
gene id: 9739:ANO3
uniprot id: A0A2U4CEH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Membrane

9739:NOP10
gene id: 9739:NOP10
uniprot id: A0A2U3UYS7
names: Similarity
messages: Belongs to the NOP10 family.

9739:ARCN1
gene id: 9739:ARCN1
uniprot id: A0A2U3V1M9
uniprot id: A0A6J3RTK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

9739:ORMDL2
gene id: 9739:ORMDL2
uniprot id: A0A2U4CRC1
uniprot id: A0A6J3S5Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

9739:NDUFA13
gene id: 9739:NDUFA13
uniprot id: A0A6J3R5V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I NDUFA13 subunit family.
messages: Complex I functions in the transfer of electrons from NADH to the respiratory chain. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.
messages: Mitochondrion inner membrane

9739:GRIK5
gene id: 9739:GRIK5
uniprot id: A0A6J3QDK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

9739:EVA1A
gene id: 9739:EVA1A
uniprot id: A0A2U4BX35
names: Similarity
messages: Belongs to the EVA1 family.

9739:SLC43A3
gene id: 9739:SLC43A3
uniprot id: A0A6J3RPF0
names: Subcellular Location Annotation
messages: Membrane

9739:AXIN2
gene id: 9739:AXIN2
uniprot id: A0A6J3QL77
uniprot id: A0A6J3QLK9
names: Subcellular Location Annotation
messages: Cytoplasm

9739:PDC
gene id: 9739:PDC
uniprot id: A0A2U3VA25
names: Similarity
messages: Belongs to the phosducin family.

9739:STAT1
gene id: 9739:STAT1
uniprot id: A0A2U4B1G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

9739:EVX2
gene id: 9739:EVX2
uniprot id: A0A2U4AAP8
names: Subcellular Location Annotation
messages: Nucleus

9739:PPP2CB
gene id: 9739:PPP2CB
uniprot id: A0A6J3QQR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family.
messages: Cytoplasm

9739:DMRTA2
gene id: 9739:DMRTA2
uniprot id: A0A2U4BJJ4
uniprot id: A0A6J3S8Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

9739:OPRD1
gene id: 9739:OPRD1
uniprot id: A0A6J3R949
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9739:LOC109549722
gene id: 9739:LOC109549722
uniprot id: A0A6J3Q0R7
names: Similarity
messages: Belongs to the snRNP Sm proteins family.

9739:TRIM32
gene id: 9739:TRIM32
uniprot id: A0A2U4C9F0
names: Similarity
messages: Belongs to the TRIM/RBCC family.

9739:LMNA
gene id: 9739:LMNA
uniprot id: A0A6J3RGW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intermediate filament family.
messages: Nucleus lamina

9739:PIH1D1
gene id: 9739:PIH1D1
uniprot id: A0A6J3QF74
uniprot id: A0A6J3QFU2
uniprot id: A0A6J3QFV5
names: Similarity
messages: Belongs to the PIH1 family.

9739:TMEM107
gene id: 9739:TMEM107
uniprot id: A0A2U3UYM0
names: Subcellular Location Annotation
messages: Membrane

9739:ABCA1
gene id: 9739:ABCA1
uniprot id: A0A2U4CGJ2
uniprot id: A0A2U4CGJ9
uniprot id: A0A2U4CGN8
names: Subcellular Location Annotation
messages: Membrane

9739:SRPX
gene id: 9739:SRPX
uniprot id: A0A2U3V3K2
uniprot id: A0A2U4C0T4
uniprot id: A0A2U4C0X1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:RAMP2
gene id: 9739:RAMP2
uniprot id: A0A6J3QNG3
names: Similarity
messages: Belongs to the RAMP family.

9739:DNAAF6
gene id: 9739:DNAAF6
uniprot id: A0A6J3QS34
names: Similarity
messages: Belongs to the PIH1 family.

9739:LOC117311882
gene id: 9739:LOC117311882
uniprot id: A0A6J3R873
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9739:MPG
gene id: 9739:MPG
uniprot id: A0A6J3PZ00
names: Function
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.
messages: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.

9739:CTNND1
gene id: 9739:CTNND1
uniprot id: A0A2U4CDB0
uniprot id: A0A2U4CDB2
uniprot id: A0A2U4CDB3
uniprot id: A0A2U4CDC3
uniprot id: A0A2U4CDC4
uniprot id: A0A2U4CDC6
names: Similarity
messages: Belongs to the beta-catenin family.

9739:ARHGAP32
gene id: 9739:ARHGAP32
uniprot id: A0A6J3RSS0
uniprot id: A0A6J3RSY3
uniprot id: A0A6J3RSZ1
uniprot id: A0A6J3RT74
uniprot id: A0A6J3RTC1
names: Similarity
messages: Belongs to the PX domain-containing GAP family.

9739:BEND6
gene id: 9739:BEND6
uniprot id: A0A6J3RYD8
names: Subcellular Location Annotation
messages: Nucleus

9739:ZNF277
gene id: 9739:ZNF277
uniprot id: A0A2U4AIN1
uniprot id: A0A2U4AIX0
uniprot id: A0A2U4AIX5
uniprot id: A0A6J3RWV9
uniprot id: A0A6J3RX08
names: Similarity
messages: Belongs to the ZNF277 family.

9739:LOC109550614
gene id: 9739:LOC109550614
uniprot id: A0A6J3QP45
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

9739:RAMAC
gene id: 9739:RAMAC
uniprot id: A0A2U4C7L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAM family.
messages: Nucleus

9739:MIGA2
gene id: 9739:MIGA2
uniprot id: A0A6J3RJY4
uniprot id: A0A6J3RKW3
names: Similarity
messages: Belongs to the mitoguardin family.

9739:CLCN7
gene id: 9739:CLCN7
uniprot id: A0A6J3Q3U4
uniprot id: A0A6J3Q427
uniprot id: A0A6J3Q487
uniprot id: A0A6J3Q4K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

9739:SCN11A
gene id: 9739:SCN11A
uniprot id: A0A6J3S260
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

9739:PHYHIP
gene id: 9739:PHYHIP
uniprot id: A0A6J3RM15
names: Similarity
messages: Belongs to the PHYHIP family.

9739:GOT1
gene id: 9739:GOT1
uniprot id: A0A2U4BQ63
uniprot id: A0A2U4BQB7
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

9739:CPLX3
gene id: 9739:CPLX3
uniprot id: A0A2U4CIL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

9739:OSBPL1A
gene id: 9739:OSBPL1A
uniprot id: A0A2U4AYK3
uniprot id: A0A2U4AYK8
uniprot id: A0A2U4AYN6
uniprot id: A0A2U4AZ16
names: Similarity
messages: Belongs to the OSBP family.

9739:SCAMP1
gene id: 9739:SCAMP1
uniprot id: A0A2U4AX23
uniprot id: A0A6J3R284
uniprot id: A0A6J3R303
uniprot id: A0A6J3R4C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

9739:MRPL2
gene id: 9739:MRPL2
uniprot id: A0A2U3V3Y1
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

9739:PHLDA1
gene id: 9739:PHLDA1
uniprot id: A0A2U3V6W0
names: Subcellular Location Annotation
messages: Cytoplasm

9739:ACOD1
gene id: 9739:ACOD1
uniprot id: A0A6J3QB59
names: Similarity
messages: Belongs to the PrpD family.

9739:FUT9
gene id: 9739:FUT9
uniprot id: A0A2U4AUW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

9739:GJB7
gene id: 9739:GJB7
uniprot id: A0A2U4AVG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9739:LOC117310291
gene id: 9739:LOC117310291
uniprot id: A0A6J3QSF4
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

9739:AFG1L
gene id: 9739:AFG1L
uniprot id: A0A2U4AVT9
uniprot id: A0A2U4AVV5
uniprot id: A0A2U4AVV7
uniprot id: A0A2U4AVX2
uniprot id: A0A2U4AWB4
uniprot id: A0A6J3S8U5
names: Similarity
messages: Belongs to the AFG1 ATPase family.

9739:FMO5
gene id: 9739:FMO5
uniprot id: A0A6J3RQ18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

9739:LOC101321995
gene id: 9739:LOC101321995
uniprot id: A0A6J3Q149
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

9739:LOC117309527
gene id: 9739:LOC117309527
uniprot id: A0A6J3QNB3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9739:LOC117308812
gene id: 9739:LOC117308812
uniprot id: A0A6J3QAV1
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

9739:UNC13B
gene id: 9739:UNC13B
uniprot id: A0A2U4CGB2
uniprot id: A0A2U4CGC1
uniprot id: A0A2U4CGF9
names: Subcellular Location Annotation
messages: Cytoplasm

9739:UBE3D
gene id: 9739:UBE3D
uniprot id: A0A2U4AVD4
uniprot id: A0A2U4AVD8
uniprot id: A0A2U4AVF5
uniprot id: A0A2U4AVU1
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.

9739:GPR68
gene id: 9739:GPR68
uniprot id: A0A6J3QWB4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9739:SGCG
gene id: 9739:SGCG
uniprot id: A0A2U4BFI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

9739:MGST1
gene id: 9739:MGST1
uniprot id: A0A2U4BHJ7
uniprot id: A0A6J3S918
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Membrane

9739:BTF3L4
gene id: 9739:BTF3L4
uniprot id: A0A2U3UZD4
names: Similarity
messages: Belongs to the NAC-beta family.

9739:LOC101325933
gene id: 9739:LOC101325933
uniprot id: A0A2U4BI75
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9739:CTSS
gene id: 9739:CTSS
uniprot id: A0A2U4A4K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

9739:DHX29
gene id: 9739:DHX29
uniprot id: A0A2U4AXA4
uniprot id: A0A2U4AXA5
uniprot id: A0A2U4AXC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity.
messages: Belongs to the DEAD box helicase family. DEAH subfamily.
messages: Cytoplasm
messages: Part of the 43S pre-initiation complex (PIC) that contains at least Met-tRNA, EIF1, EIF1A (EIF1AX or EIF1AY), EIF2S1, EIF2S2, EIF2S3, EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L, EIF3M, DHX29 and the 40S ribosomal subunit.

9739:SERPINB5
gene id: 9739:SERPINB5
uniprot id: A0A2U4BHV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the serpin family. Ov-serpin subfamily.
messages: extracellular space

9739:FRAS1
gene id: 9739:FRAS1
uniprot id: A0A6J3RE43
uniprot id: A0A6J3RE49
uniprot id: A0A6J3RE69
uniprot id: A0A6J3REP8
uniprot id: A0A6J3REQ3
uniprot id: A0A6J3REZ4
uniprot id: A0A6J3RGF6
uniprot id: A0A6J3RGG1
names: Similarity
messages: Belongs to the FRAS1 family.

9739:GAP43
gene id: 9739:GAP43
uniprot id: A0A2U4AA05
uniprot id: A0A6J3RCU1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the neuromodulin family.
messages: Cell membrane
messages: Cytoplasm
messages: Identified in a complex containing FGFR4, NCAM1, CDH2, PLCG1, FRS2, SRC, SHC1, GAP43 and CTTN. Interacts (via IQ domain) with calmodulin. Binds calmodulin with a greater affinity in the absence of Ca(2+) than in its presence.
messages: Membrane
messages: Palmitoylated. Palmitoylation is essential for plasma membrane association.
messages: Perikaryon
messages: Synapse
messages: This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.
messages: axon
messages: dendrite
messages: filopodium membrane
messages: growth cone membrane

9739:BMT2
gene id: 9739:BMT2
uniprot id: A0A2U4AIW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BMT2 family.
messages: Interacts with the GATOR1 complex; interaction is disrupted when BMT2/SAMTOR binds S-adenosyl-L-methionine. Interacts with the KICSTOR complex; interaction is disrupted when BMT2/SAMTOR binds S-adenosyl-L-methionine.
messages: S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 signaling. Probably also acts as a S-adenosyl-L-methionine-dependent methyltransferase.

9739:LOC101330131
gene id: 9739:LOC101330131
uniprot id: A0A6J3Q0S8
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:RANBP17
gene id: 9739:RANBP17
uniprot id: A0A2U4C7E1
uniprot id: A0A2U4C7N7
uniprot id: A0A6J3R4R3
uniprot id: A0A6J3R674
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus

9739:DRD4
gene id: 9739:DRD4
uniprot id: A0A6J3RSN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9739:SLC35B1
gene id: 9739:SLC35B1
uniprot id: A0A2U3V4U7
uniprot id: A0A2U4AHL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

9739:FAM110A
gene id: 9739:FAM110A
uniprot id: A0A6J3PYK9
names: Similarity
messages: Belongs to the FAM110 family.

9739:LOC117308965
gene id: 9739:LOC117308965
uniprot id: A0A6J3QDB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lambda interferon family.
messages: Secreted

9739:TRAPPC4
gene id: 9739:TRAPPC4
uniprot id: A0A2U4BW24
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

9739:BPGM
gene id: 9739:BPGM
uniprot id: A0A2U3V9E2
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

9739:INHBB
gene id: 9739:INHBB
uniprot id: A0A6J3RN70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

9739:BLK
gene id: 9739:BLK
uniprot id: A0A6J3RFT6
uniprot id: A0A6J3RHL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

9739:KEG93 p04
gene id: 9739:KEG93_p04
uniprot id: B9UD85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4 family.
messages: Core subunit of respiratory chain NADH dehydrogenase (Complex I) which is composed of 45 different subunits.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion membrane

9739:FARSA
gene id: 9739:FARSA
uniprot id: A0A2U4AZC0
uniprot id: A0A2U4AZD1
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.

9739:PPFIA2
gene id: 9739:PPFIA2
uniprot id: A0A6J3S5J4
uniprot id: A0A6J3S5P6
uniprot id: A0A6J3S6M4
uniprot id: A0A6J3S6W7
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

9739:MRPL33
gene id: 9739:MRPL33
uniprot id: A0A2U4BZF5
uniprot id: A0A2U4BZF7
uniprot id: A0A2U4BZK0
uniprot id: A0A2U4BZK2
uniprot id: A0A6J3PXJ1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

9739:AMBN
gene id: 9739:AMBN
uniprot id: A0A2U4B556
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ameloblastin family.
messages: Involved in the mineralization and structural organization of enamel.
messages: extracellular matrix

9739:PAN3
gene id: 9739:PAN3
uniprot id: A0A2U4BGN2
uniprot id: A0A6J3QB50
uniprot id: A0A6J3QBC7
uniprot id: A0A6J3QBP0
uniprot id: A0A6J3QBW3
uniprot id: A0A6J3QC42
uniprot id: A0A6J3QC47
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. PAN3 family.
messages: Contains a pseudokinase domain. The protein kinase domain is predicted to be catalytically inactive because some of the residues important for catalytic activity are substituted and it lacks the equivalent of the binding site for a peptide substrate. However, it has retained an ATP-binding site and ATP-binding is required for mRNA degradation, stimulating the activity of the PAN2 nuclease in vitro. The nucleotide-binding site is juxtaposed to the RNase active site of PAN2 in the complex and may actually bind nucleosides of a poly(A) RNA rather than ATP, feeding the poly(A)-tail to the active site of the deadenylase and thus increasing the efficiency with which this distributive enzyme degrades oligo(A) RNAs.
messages: Homodimer. Forms a heterotrimer with a catalytic subunit PAN2 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts (via PAM-2 motif) with poly(A)-binding protein PABPC1 (via PABC domain), conferring substrate specificity of the enzyme complex. Interacts with the GW182 family proteins TNRC6A, TNRC6B and TNRC6C.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: P-body
messages: Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and PABP, and to miRNA targets via its interaction with GW182 family proteins.
messages: The N-terminal zinc finger binds to poly(A) RNA.
messages: The pseudokinase domain, the coiled-coil (CC), and C-terminal knob domain (CK) form a structural unit (PKC) that forms an extensive high-affinity interaction surface for PAN2.

9739:PEX5
gene id: 9739:PEX5
uniprot id: A0A2U4AKT2
uniprot id: A0A2U4AKT3
uniprot id: A0A2U4AKT5
uniprot id: A0A2U4AKX6
uniprot id: A0A2U4AL91
names: Similarity
messages: Belongs to the peroxisomal targeting signal receptor family.

9739:BTG2
gene id: 9739:BTG2
uniprot id: A0A2U3ZZ72
names: Similarity
messages: Belongs to the BTG family.

9739:LOC101327933
gene id: 9739:LOC101327933
uniprot id: A0A2U4B4W4
uniprot id: A0A2U4B506
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

9739:LOC101325454
gene id: 9739:LOC101325454
uniprot id: A0A6J3PTW7
names: Similarity
messages: Belongs to the TGF-beta family.

9739:PDE9A
gene id: 9739:PDE9A
uniprot id: A0A6J3RB17
uniprot id: A0A6J3RB98
uniprot id: A0A6J3RBR9
uniprot id: A0A6J3RBS4
uniprot id: A0A6J3RC06
uniprot id: A0A6J3RC11
uniprot id: A0A6J3RDN6
uniprot id: A0A6J3RDP1
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9739:KIAA1191
gene id: 9739:KIAA1191
uniprot id: A0A6J3R4U2
uniprot id: A0A6J3R6A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P33MONOX family.
messages: Cytoplasm
messages: Interacts with NELFB, NOL12 and PRNP.
messages: Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth.

9739:DDAH2
gene id: 9739:DDAH2
uniprot id: A0A6J3RZJ2
names: Function
names: Similarity
messages: Belongs to the DDAH family.
messages: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.

9739:ISM1
gene id: 9739:ISM1
uniprot id: A0A2U4BUV8
uniprot id: A0A2U4BV35
names: Similarity
messages: Belongs to the isthmin family.

9739:PI4KA
gene id: 9739:PI4KA
uniprot id: A0A6J3PSV8
uniprot id: A0A6J3PSW3
uniprot id: A0A6J3PT11
uniprot id: A0A6J3PT17
uniprot id: A0A6J3PTF6
uniprot id: A0A6J3PTG5
uniprot id: A0A6J3PTH1
uniprot id: A0A6J3PTZ3
uniprot id: A0A6J3PTZ8
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

9739:KPNA4
gene id: 9739:KPNA4
uniprot id: A0A2U4C8N2
uniprot id: A0A6J3RA32
names: Function
names: Similarity
messages: Belongs to the importin alpha family.
messages: Functions in nuclear protein import.

9739:UBE2D1
gene id: 9739:UBE2D1
uniprot id: A0A2U4BCE1
uniprot id: A0A2U4BCJ2
uniprot id: A0A2U4BCL2
uniprot id: A0A2U4BCW7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9739:PRKAR2B
gene id: 9739:PRKAR2B
uniprot id: A0A2U4BSH9
uniprot id: A0A6J3RW79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

9739:ERBB4
gene id: 9739:ERBB4
uniprot id: A0A6J3RLJ8
uniprot id: A0A6J3RLZ7
uniprot id: A0A6J3RMD0
uniprot id: A0A6J3RMX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

9739:APOO
gene id: 9739:APOO
uniprot id: A0A2U4AQN2
uniprot id: A0A2U4AQN6
uniprot id: A0A2U4AR23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

9739:SLC40A1
gene id: 9739:SLC40A1
uniprot id: A0A2U3V3I5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lateral cell membrane
messages: May be involved in iron transport and iron homeostasis.
messages: Membrane

9739:KCNK17
gene id: 9739:KCNK17
uniprot id: A0A6J3S066
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

9739:ATP6V0A1
gene id: 9739:ATP6V0A1
uniprot id: A0A6J3QL07
uniprot id: A0A6J3QL12
uniprot id: A0A6J3QL50
uniprot id: A0A6J3QL55
uniprot id: A0A6J3QLP1
uniprot id: A0A6J3QLR2
uniprot id: A0A6J3QM64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

9739:SMAD9
gene id: 9739:SMAD9
uniprot id: A0A2U4BGU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

9739:JPT2
gene id: 9739:JPT2
uniprot id: A0A2U3VB39
uniprot id: A0A2U4BM98
uniprot id: A0A2U4BMG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

9739:PDE4C
gene id: 9739:PDE4C
uniprot id: A0A6J3R8W3
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9739:EML4
gene id: 9739:EML4
uniprot id: A0A2U4BYI3
uniprot id: A0A2U4BYI6
uniprot id: A0A2U4BYI8
uniprot id: A0A2U4BYM7
uniprot id: A0A2U4BYN1
uniprot id: A0A2U4BYP0
uniprot id: A0A2U4BYP2
names: Similarity
messages: Belongs to the WD repeat EMAP family.

9739:TPRG1L
gene id: 9739:TPRG1L
uniprot id: A0A2U4B004
uniprot id: A0A2U4B0E4
names: Similarity
messages: Belongs to the TPRG1 family.

9739:LOC109552244
gene id: 9739:LOC109552244
uniprot id: A0A6J3RUL4
names: Subcellular Location Annotation
messages: Membrane

9739:CHST4
gene id: 9739:CHST4
uniprot id: A0A2U4BD14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

9739:APOB
gene id: 9739:APOB
uniprot id: A0A2U4C0C1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:SRSF1
gene id: 9739:SRSF1
uniprot id: A0A2U3V959
names: Similarity
messages: Belongs to the splicing factor SR family.

9739:ZC3H14
gene id: 9739:ZC3H14
uniprot id: A0A2U4A1F2
uniprot id: A0A2U4A1H7
uniprot id: A0A2U4A1I6
uniprot id: A0A2U4A1J2
uniprot id: A0A2U4A1J6
uniprot id: A0A2U4A1K9
uniprot id: A0A2U4A1M8
uniprot id: A0A2U4A1N4
uniprot id: A0A2U4A1P0
uniprot id: A0A2U4A1Q9
uniprot id: A0A2U4A2E2
uniprot id: A0A2U4A2F4
uniprot id: A0A2U4A2N0
uniprot id: A0A2U4A2N8
uniprot id: A0A2U4A2S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZC3H14 family.
messages: Involved in poly(A) tail length control in neuronal cells. Binds the polyadenosine RNA oligonucleotides.
messages: Nucleus speckle

9739:FGF22
gene id: 9739:FGF22
uniprot id: A0A6J3R844
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9739:GNMT
gene id: 9739:GNMT
uniprot id: A0A6J3RZZ6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family.

9739:LOC101336435
gene id: 9739:LOC101336435
uniprot id: A0A2U4B4S6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

9739:AIF1
gene id: 9739:AIF1
uniprot id: A0A2U3UYZ1
names: Subcellular Location Annotation
messages: ruffle membrane

9739:LOC117308674
gene id: 9739:LOC117308674
uniprot id: A0A2U4BSY5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

9739:LSM12
gene id: 9739:LSM12
uniprot id: A0A2U4BP81
names: Similarity
messages: Belongs to the LSM12 family.

9739:DHRS11
gene id: 9739:DHRS11
uniprot id: A0A6J3QJM6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9739:ITIH1
gene id: 9739:ITIH1
uniprot id: A0A6J3S3D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

9739:CSTF3
gene id: 9739:CSTF3
uniprot id: A0A2U3V1X3
uniprot id: A0A2U4CDU2
names: Subcellular Location Annotation
messages: Nucleus

9739:IGFBP4
gene id: 9739:IGFBP4
uniprot id: A0A6J3QM19
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds IGF2 more than IGF1.
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9739:LOC101321996
gene id: 9739:LOC101321996
uniprot id: A0A2U4CC08
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Binds directly to 26S ribosomal RNA.

9739:DSC3
gene id: 9739:DSC3
uniprot id: A0A2U4AYI2
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

9739:BNIP1
gene id: 9739:BNIP1
uniprot id: A0A2U4C8D3
names: Subcellular Location Annotation
messages: Membrane

9739:CCBE1
gene id: 9739:CCBE1
uniprot id: A0A6J3PUA2
uniprot id: A0A6J3PUP2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:LOC101333665
gene id: 9739:LOC101333665
uniprot id: A0A2U4BWK0
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

9739:NUDT17
gene id: 9739:NUDT17
uniprot id: A0A2U3V3I3
uniprot id: A0A2U4A187
uniprot id: A0A2U4A192
uniprot id: A0A2U4A194
uniprot id: A0A2U4A195
uniprot id: A0A2U4A198
uniprot id: A0A2U4A1A0
uniprot id: A0A2U4A289
names: Function
names: Similarity
messages: Belongs to the Nudix hydrolase family.
messages: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.

9739:PFKFB1
gene id: 9739:PFKFB1
uniprot id: A0A6J3QRL1
uniprot id: A0A6J3QSG7
uniprot id: A0A6J3QT09
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

9739:RNF40
gene id: 9739:RNF40
uniprot id: A0A6J3Q0I0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BRE1 family.
messages: Component of the RNF20/40 complex (also known as BRE1 complex) probably composed of 2 copies of RNF20/BRE1A and 2 copies of RNF40/BRE1B. Interacts with UBE2E1/UBCH6.
messages: Nucleus

9739:LOC117312759
gene id: 9739:LOC117312759
uniprot id: A0A6J3RKC3
names: Similarity
messages: Belongs to the SPATA31 family.

9739:ZHX1
gene id: 9739:ZHX1
uniprot id: A0A2U4B3F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

9739:CACNB4
gene id: 9739:CACNB4
uniprot id: A0A2U4AD01
names: Similarity
messages: Belongs to the calcium channel beta subunit family.

9739:ENTPD4
gene id: 9739:ENTPD4
uniprot id: A0A2U4BUL3
uniprot id: A0A2U4BUQ1
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

9739:EEF2KMT
gene id: 9739:EEF2KMT
uniprot id: A0A2U4ATM3
uniprot id: A0A2U4ATN0
uniprot id: A0A2U4ATN2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EEF2KMT family.

9739:TIMM13
gene id: 9739:TIMM13
uniprot id: A0A2U4A6I6
uniprot id: A0A2U4A6N1
uniprot id: A0A6J3R8K1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

9739:TSPYL2
gene id: 9739:TSPYL2
uniprot id: A0A6J3QSN8
uniprot id: A0A6J3QST5
uniprot id: A0A6J3QTD2
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9739:OCIAD1
gene id: 9739:OCIAD1
uniprot id: A0A2U4AS30
uniprot id: A0A2U4AS41
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OCIAD1 family.
messages: Endosome
messages: Interacts with STAT3.
messages: Maintains stem cell potency. Increases STAT3 phosphorylation and controls ERK phosphorylation. May act as a scaffold, increasing STAT3 recruitment onto endosomes.
messages: The OCIA domain is necessary and sufficient for endosomal localization.

9739:TMEM131
gene id: 9739:TMEM131
uniprot id: A0A2U4B0G1
uniprot id: A0A2U4B0G2
uniprot id: A0A2U4B0G5
uniprot id: A0A2U4B0G6
uniprot id: A0A2U4B0G7
uniprot id: A0A2U4B0J2
uniprot id: A0A2U4B0J7
uniprot id: A0A2U4B0T8
names: Similarity
messages: Belongs to the TMEM131 family.

9739:LOC101327590
gene id: 9739:LOC101327590
uniprot id: A0A6J3RU51
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

9739:SLC11A2
gene id: 9739:SLC11A2
uniprot id: A0A2U4CBJ9
uniprot id: A0A6J3S6R6
uniprot id: A0A6J3S7V3
uniprot id: A0A6J3S874
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Macrophage-specific antiporter that fluxes metal ions in either direction against a proton gradient. Localized to late endosomal lysosomal membranes, delivers bivalent cations from the cytosol into these acidic compartments where they may directly affect antimicrobial activity. Involved in iron metabolism and host natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis of its protective enzymes.

9739:TMEM123
gene id: 9739:TMEM123
uniprot id: A0A2U4AEG2
uniprot id: A0A2U4AEG4
uniprot id: A0A2U4AEM0
uniprot id: A0A2U4AEX3
uniprot id: A0A6J3RU33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD164 family.
messages: Membrane

9739:NKX3-2
gene id: 9739:NKX3-2
uniprot id: A0A6J3RFU2
names: Subcellular Location Annotation
messages: Nucleus

9739:SEZ6L
gene id: 9739:SEZ6L
uniprot id: A0A6J3PVC4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:TAS1R1
gene id: 9739:TAS1R1
uniprot id: A0A6J3QCM8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9739:CENPU
gene id: 9739:CENPU
uniprot id: A0A2U3V084
uniprot id: A0A2U4A8H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-U/AME1 family.
messages: Nucleus

9739:NUP205
gene id: 9739:NUP205
uniprot id: A0A2U4CMR9
uniprot id: A0A2U4CMT1
names: Similarity
messages: Belongs to the NUP186/NUP192/NUP205 family.

9739:MRPL17
gene id: 9739:MRPL17
uniprot id: A0A2U3V866
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

9739:ALG5
gene id: 9739:ALG5
uniprot id: A0A2U4BGF4
uniprot id: A0A2U4BGF8
uniprot id: A0A2U4BGJ0
uniprot id: A0A2U4BGU1
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

9739:HENMT1
gene id: 9739:HENMT1
uniprot id: A0A2U4A286
names: Similarity
messages: Belongs to the methyltransferase superfamily. HEN1 family.

9739:TRPV2
gene id: 9739:TRPV2
uniprot id: A0A2U4C2J8
uniprot id: A0A2U4C2P6
uniprot id: A0A6J3QPU1
uniprot id: A0A6J3QQD5
uniprot id: A0A6J3QQW3
names: Subcellular Location Annotation
messages: Membrane

9739:LOC101326262
gene id: 9739:LOC101326262
uniprot id: A0A2U4B8M0
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

9739:TBC1D23
gene id: 9739:TBC1D23
uniprot id: A0A2U4AB78
uniprot id: A0A2U4ABE3
names: Subcellular Location Annotation
messages: trans-Golgi network

9739:C4H3orf70
gene id: 9739:C4H3orf70
uniprot id: A0A2U4C8I2
names: Similarity
messages: Belongs to the UPF0524 family.

9739:LOC101316984
gene id: 9739:LOC101316984
uniprot id: A0A2U4A391
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

9739:PAPOLA
gene id: 9739:PAPOLA
uniprot id: A0A2U4CRU2
uniprot id: A0A2U4CRV1
uniprot id: A0A2U4CRY2
uniprot id: A0A2U4CRZ1
uniprot id: A0A2U4CS00
uniprot id: A0A2U4CS07
uniprot id: A0A2U4CS18
uniprot id: A0A6J3QVL4
uniprot id: A0A6J3QVY4
uniprot id: A0A6J3QVY6
uniprot id: A0A6J3QW51
uniprot id: A0A6J3QW55
uniprot id: A0A6J3QWL0
uniprot id: A0A6J3QXI5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Binds 2 magnesium ions. Also active with manganese.
messages: Nucleus
messages: Polymerase that creates the 3'-poly(A) tail of mRNA's.

9739:PAX2
gene id: 9739:PAX2
uniprot id: A0A6J3Q5J7
uniprot id: A0A6J3Q5K5
uniprot id: A0A6J3Q5K9
uniprot id: A0A6J3Q5U0
uniprot id: A0A6J3Q660
uniprot id: A0A6J3Q6B7
names: Subcellular Location Annotation
messages: Nucleus

9739:TEAD1
gene id: 9739:TEAD1
uniprot id: A0A2U4CDV7
uniprot id: A0A2U4CDV9
uniprot id: A0A2U4CDW3
uniprot id: A0A2U4CDW9
uniprot id: A0A2U4CDY0
uniprot id: A0A6J3RV67
uniprot id: A0A6J3RV79
uniprot id: A0A6J3RVB2
uniprot id: A0A6J3RVB5
uniprot id: A0A6J3RVT1
names: Subcellular Location Annotation
messages: Nucleus

9739:SEM1
gene id: 9739:SEM1
uniprot id: A0A6J3S2H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DSS1/SEM1 family.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Nucleus

9739:CEP55
gene id: 9739:CEP55
uniprot id: A0A2U4BPQ9
uniprot id: A0A2U4BPS5
uniprot id: A0A6J3Q6S4
names: Subcellular Location Annotation
messages: Cytoplasm

9739:ARHGDIB
gene id: 9739:ARHGDIB
uniprot id: A0A2U3V840
names: Similarity
messages: Belongs to the Rho GDI family.

9739:MICOS10
gene id: 9739:MICOS10
uniprot id: A0A2U4A0K3
uniprot id: A0A2U4A1I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic10 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

9739:FANCC
gene id: 9739:FANCC
uniprot id: A0A6J3RIC4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the multisubunit FA complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. This complex may also include HSP70.
messages: DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.
messages: Nucleus

9739:PROK2
gene id: 9739:PROK2
uniprot id: A0A2U4CCJ5
uniprot id: A0A2U4CCM8
uniprot id: A0A6J3S2S8
uniprot id: A0A6J3S3T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AVIT (prokineticin) family.
messages: Secreted

9739:PHF1
gene id: 9739:PHF1
uniprot id: A0A6J3S0A4
uniprot id: A0A6J3S0G4
uniprot id: A0A6J3S0W9
uniprot id: A0A6J3S1C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus

9739:CDCP2
gene id: 9739:CDCP2
uniprot id: A0A6J3R267
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:PTPRE
gene id: 9739:PTPRE
uniprot id: A0A6J3Q6I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 4 subfamily.
messages: Cell membrane
messages: Membrane

9739:MFGE8
gene id: 9739:MFGE8
uniprot id: A0A6J3R1R7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:PPP2R2A
gene id: 9739:PPP2R2A
uniprot id: A0A2U3V4W8
uniprot id: A0A2U4BUJ7
uniprot id: A0A2U4BUP5
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

9739:ST6GALNAC4
gene id: 9739:ST6GALNAC4
uniprot id: A0A6J3RIS4
uniprot id: A0A6J3RIS9
uniprot id: A0A6J3RIT9
uniprot id: A0A6J3RIU3
uniprot id: A0A6J3RJI8
uniprot id: A0A6J3RJJ3
uniprot id: A0A6J3RKI6
uniprot id: A0A6J3RKJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9739:NUDT6
gene id: 9739:NUDT6
uniprot id: A0A2U4AR62
uniprot id: A0A2U4AR63
uniprot id: A0A2U4AR68
uniprot id: A0A2U4AR71
uniprot id: A0A2U4ARL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Cytoplasm
messages: May contribute to the regulation of cell proliferation.
messages: Mitochondrion
messages: Monomer and homodimer.
messages: Nucleus

9739:CD40
gene id: 9739:CD40
uniprot id: A0A2U4C2B2
uniprot id: A0A6J3Q1J3
uniprot id: A0A6J3Q1P1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:WARS2
gene id: 9739:WARS2
uniprot id: A0A2U3V425
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9739:ETF1
gene id: 9739:ETF1
uniprot id: A0A2U4AGG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm

9739:CLDN6
gene id: 9739:CLDN6
uniprot id: A0A6J3Q4V6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9739:CDK10
gene id: 9739:CDK10
uniprot id: A0A6J3QDZ4
uniprot id: A0A6J3QEH8
uniprot id: A0A6J3QEY6
uniprot id: A0A6J3QEZ1
names: Similarity
messages: Belongs to the protein kinase superfamily.

9739:RPL22
gene id: 9739:RPL22
uniprot id: A0A2U3V052
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

9739:TUBA8
gene id: 9739:TUBA8
uniprot id: A0A2U4AK99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

9739:LOC117310180
gene id: 9739:LOC117310180
uniprot id: A0A6J3QT46
names: Similarity
messages: Belongs to the PRAME family.

9739:XPA
gene id: 9739:XPA
uniprot id: A0A2U4CG79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPA family.
messages: Nucleus

9739:LOC101323012
gene id: 9739:LOC101323012
uniprot id: A0A6J3S8F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDK2AP family.
messages: Nucleus

9739:LIPN
gene id: 9739:LIPN
uniprot id: A0A2U4BQZ0
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

9739:ARHGAP26
gene id: 9739:ARHGAP26
uniprot id: A0A2U4AGS5
uniprot id: A0A2U4AGS7
uniprot id: A0A2U4AGT7
uniprot id: A0A2U4AH93
names: Subcellular Location Annotation
messages: cytoskeleton
messages: focal adhesion

9739:GRINA
gene id: 9739:GRINA
uniprot id: A0A6J3Q9E6
names: Subcellular Location Annotation
messages: Membrane

9739:OTOP1
gene id: 9739:OTOP1
uniprot id: A0A6J3RD82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

9739:LOC101338700
gene id: 9739:LOC101338700
uniprot id: A0A6J3RN72
names: Cofactor
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.

9739:FAT4
gene id: 9739:FAT4
uniprot id: A0A2U4AR80
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:LOC117309129
gene id: 9739:LOC117309129
uniprot id: A0A6J3QGR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

9739:SLC35A2
gene id: 9739:SLC35A2
uniprot id: A0A2U3V5L5
uniprot id: A0A6J3QSH6
uniprot id: A0A6J3QT39
uniprot id: A0A6J3QTI4
uniprot id: A0A6J3QU36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9739:ATP5F1B
gene id: 9739:ATP5F1B
uniprot id: A0A2U3V1W9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

9739:LIN7C
gene id: 9739:LIN7C
uniprot id: A0A2U3V3R4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the lin-7 family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.
messages: Postsynaptic density membrane
messages: tight junction

9739:IL5
gene id: 9739:IL5
uniprot id: A0A2U3V2V3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-5 family.
messages: Homodimer; disulfide-linked. Interacts with IL5RA. Interacts with CSF2RB.
messages: Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Acts also on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation (By similarity). Mechanistically, exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB. Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively.
messages: Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Acts also on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation. Mechanistically, exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB. Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively.
messages: Secreted

9739:TSSK6
gene id: 9739:TSSK6
uniprot id: A0A2U3V033
names: Similarity
messages: Belongs to the protein kinase superfamily.

9739:PARPBP
gene id: 9739:PARPBP
uniprot id: A0A2U3ZZD0
uniprot id: A0A2U3ZZE7
uniprot id: A0A6J3S5F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PARI family.
messages: Cytoplasm
messages: Nucleus

9739:DESI2
gene id: 9739:DESI2
uniprot id: A0A2U3V823
uniprot id: A0A2U4A5S2
uniprot id: A0A6J3QYW9
uniprot id: A0A6J3QZG4
names: Similarity
messages: Belongs to the DeSI family.

9739:RGMB
gene id: 9739:RGMB
uniprot id: A0A6J3R3A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

9739:GRK7
gene id: 9739:GRK7
uniprot id: A0A2U3UZM9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

9739:TNNI3
gene id: 9739:TNNI3
uniprot id: A0A6J3QHU9
names: Function
names: Similarity
messages: Belongs to the troponin I family.
messages: Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

9739:AMER3
gene id: 9739:AMER3
uniprot id: A0A6J3RP50
names: Similarity
messages: Belongs to the Amer family.

9739:IMP4
gene id: 9739:IMP4
uniprot id: A0A2U4B2N3
names: Subcellular Location Annotation
messages: nucleolus

9739:AIG1
gene id: 9739:AIG1
uniprot id: A0A2U4CPV1
uniprot id: A0A2U4CQ57
uniprot id: A0A6J3SA11
uniprot id: A0A6J3SAU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIG1 family.
messages: Membrane

9739:PRPF31
gene id: 9739:PRPF31
uniprot id: A0A6J3QH24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP31 family.
messages: Cajal body

9739:KIF20A
gene id: 9739:KIF20A
uniprot id: A0A2U3UZG1
uniprot id: A0A6J3R3G7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9739:ADAMTS12
gene id: 9739:ADAMTS12
uniprot id: A0A6J3R1P8
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9739:SKIV2L
gene id: 9739:SKIV2L
uniprot id: A0A6J3RZC2
uniprot id: A0A6J3RZN6
uniprot id: A0A6J3S0B8
names: Subcellular Location Annotation
messages: Cytoplasm

9739:MACF1
gene id: 9739:MACF1
uniprot id: A0A2U4BK70
uniprot id: A0A2U4BKL1
uniprot id: A0A6J3PTD1
uniprot id: A0A6J3PTE8
uniprot id: A0A6J3PTG3
uniprot id: A0A6J3PTK6
uniprot id: A0A6J3PU02
uniprot id: A0A6J3PU17
uniprot id: A0A6J3PU22
names: Subcellular Location Annotation
messages: cytoskeleton

9739:CCL24
gene id: 9739:CCL24
uniprot id: A0A2U3V710
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.

9739:PROM2
gene id: 9739:PROM2
uniprot id: A0A6J3PVM5
uniprot id: A0A6J3PW95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prominin family.
messages: Membrane
messages: microvillus membrane

9739:CMTR1
gene id: 9739:CMTR1
uniprot id: A0A6J3S008
uniprot id: A0A6J3S014
uniprot id: A0A6J3S075
uniprot id: A0A6J3S078
uniprot id: A0A6J3S0I4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with POLR2A (via C-terminus).
messages: Nucleus
messages: S-adenosyl-L-methionine-dependent methyltransferase that mediates RNA cap1 2'-O-ribose methylation to the 5'-cap structure of RNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA to produce m(7)GpppNmp (cap1).
messages: S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway.

9739:DPYD
gene id: 9739:DPYD
uniprot id: A0A2U4A3K2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.
messages: Binds 4 [4Fe-4S] clusters. Contains approximately 16 iron atoms per subunit.
messages: Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine.

9739:GLRA2
gene id: 9739:GLRA2
uniprot id: A0A2U4AJR0
uniprot id: A0A2U4AJX8
uniprot id: A0A2U4AK98
uniprot id: A0A2U4AKA4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

9739:ANO9
gene id: 9739:ANO9
uniprot id: A0A6J3RSS1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:MCUR1
gene id: 9739:MCUR1
uniprot id: A0A2U3V3M2
uniprot id: A0A2U4C5I6
uniprot id: A0A2U4C5J7
uniprot id: A0A2U4C5J9
uniprot id: A0A2U4C5K0
uniprot id: A0A2U4C5R8
uniprot id: A0A2U4C5S2
names: Similarity
messages: Belongs to the CCDC90 family.

9739:NKAPL
gene id: 9739:NKAPL
uniprot id: A0A2U3VAH3
names: Similarity
messages: Belongs to the NKAP family.

9739:NXF1
gene id: 9739:NXF1
uniprot id: A0A2U4B4L0
uniprot id: A0A2U4B4L2
uniprot id: A0A2U4B4M4
uniprot id: A0A2U4B4R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NXF family.
messages: Cytoplasm
messages: nucleoplasm

9739:SIAH3
gene id: 9739:SIAH3
uniprot id: A0A2U4BFK3
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

9739:SLC35A3
gene id: 9739:SLC35A3
uniprot id: A0A2U4A1D2
uniprot id: A0A2U4A1D3
uniprot id: A0A2U4A1D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9739:CDKL4
gene id: 9739:CDKL4
uniprot id: A0A2U4BY67
names: Similarity
messages: Belongs to the protein kinase superfamily.

9739:LOC101333156
gene id: 9739:LOC101333156
uniprot id: A0A2U4CL76
uniprot id: A0A2U4CL79
uniprot id: A0A6J3Q495
names: Similarity
messages: Belongs to the CBP3 family.

9739:DPCD
gene id: 9739:DPCD
uniprot id: A0A6J3Q662
uniprot id: A0A6J3Q6X6
uniprot id: A0A6J3Q6Y7
names: Similarity
messages: Belongs to the DPCD family.

9739:GALK2
gene id: 9739:GALK2
uniprot id: A0A2U4AUW5
uniprot id: A0A2U4AUX4
uniprot id: A0A2U4AUX8
uniprot id: A0A2U4AUZ5
uniprot id: A0A2U4AV00
uniprot id: A0A6J3R0B1
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

9739:SEMA4B
gene id: 9739:SEMA4B
uniprot id: A0A2U4C6Y2
uniprot id: A0A6J3R0M9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:FAH
gene id: 9739:FAH
uniprot id: A0A6J3R041
uniprot id: A0A6J3R0F0
uniprot id: A0A6J3R0S6
uniprot id: A0A6J3R0X0
uniprot id: A0A6J3R266
names: Similarity
messages: Belongs to the FAH family.

9739:SPDL1
gene id: 9739:SPDL1
uniprot id: A0A2U3V6L2
uniprot id: A0A6J3R409
uniprot id: A0A6J3R4Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Spindly family.
messages: Interacts with KNTC1 and ZW10. These interactions appear weak and may be transient or indirect.
messages: Nucleus
messages: Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment.
messages: centrosome
messages: kinetochore
messages: spindle pole

9739:PLCB3
gene id: 9739:PLCB3
uniprot id: A0A6J3RQ15
uniprot id: A0A6J3RQG3
uniprot id: A0A6J3RR34
names: Cofactor
names: Function
messages: Binds 1 Ca(2+) ion per subunit.
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

9739:PLPPR2
gene id: 9739:PLPPR2
uniprot id: A0A6J3R5R6
uniprot id: A0A6J3R6C8
uniprot id: A0A6J3R8H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

9739:IGFBP1
gene id: 9739:IGFBP1
uniprot id: A0A2U3V9L2
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds equally well IGF1 and IGF2.
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9739:TAF11
gene id: 9739:TAF11
uniprot id: A0A6J3S088
uniprot id: A0A6J3S0Q6
names: Similarity
messages: Belongs to the TAF11 family.

9739:LOC117312099
gene id: 9739:LOC117312099
uniprot id: A0A6J3R8E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

9739:FGB
gene id: 9739:FGB
uniprot id: A0A6J3RC29
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

9739:GALNT1
gene id: 9739:GALNT1
uniprot id: A0A6J3PTP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9739:VPS72
gene id: 9739:VPS72
uniprot id: A0A2U4A3K0
names: Function
names: Similarity
messages: Belongs to the VPS72/YL1 family.
messages: Deposition-and-exchange histone chaperone specific for H2AZ1, specifically chaperones H2AZ1 and deposits it into nucleosomes. As component of the SRCAP complex, mediates the ATP-dependent exchange of histone H2AZ1/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling.

9739:GPHB5
gene id: 9739:GPHB5
uniprot id: A0A2U3V0L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

9739:PTGIR
gene id: 9739:PTGIR
uniprot id: A0A6J3QF12
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9739:PALM2AKAP2
gene id: 9739:PALM2AKAP2
uniprot id: A0A2U4C932
uniprot id: A0A2U4C935
uniprot id: A0A2U4C936
uniprot id: A0A2U4C9C1
uniprot id: A0A6J3RHN5
uniprot id: A0A6J3RI33
uniprot id: A0A6J3RJQ8
names: Similarity
messages: Belongs to the paralemmin family.

9739:MSRB2
gene id: 9739:MSRB2
uniprot id: A0A2U4B798
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.
messages: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.

9739:PHETA2
gene id: 9739:PHETA2
uniprot id: A0A2U4A5K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sesquipedalian family.
messages: Early endosome
messages: Forms homodimers and heterodimers with PHETA. Interacts with OCRL and INPP5B.
messages: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
messages: Recycling endosome
messages: clathrin-coated vesicle
messages: trans-Golgi network

9739:LOC117311194
gene id: 9739:LOC117311194
uniprot id: A0A6J3R1M5
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

9739:MRPL20
gene id: 9739:MRPL20
uniprot id: A0A6J3QGR6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.

9739:FCHO2
gene id: 9739:FCHO2
uniprot id: A0A2U4AWS3
uniprot id: A0A2U4AWT5
uniprot id: A0A2U4AWT6
uniprot id: A0A2U4AWU0
uniprot id: A0A2U4AWV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FCHO family.
messages: clathrin-coated pit

9739:TAS1R3
gene id: 9739:TAS1R3
uniprot id: A0A2U4BXE1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9739:CCN2
gene id: 9739:CCN2
uniprot id: A0A2U4CPV5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9739:RSBN1L
gene id: 9739:RSBN1L
uniprot id: A0A2U4BS87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the round spermatid basic protein 1 family.
messages: Nucleus

9739:TRIM21
gene id: 9739:TRIM21
uniprot id: A0A6J3RUY7
names: Subcellular Location Annotation
messages: Cytoplasm

9739:RUVBL2
gene id: 9739:RUVBL2
uniprot id: A0A6J3QGS0
uniprot id: A0A6J3QHB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Dynein axonemal particle
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

9739:USP35
gene id: 9739:USP35
uniprot id: A0A6J3RUA4
uniprot id: A0A6J3RUM7
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

9739:CHGA
gene id: 9739:CHGA
uniprot id: A0A6J3QW90
uniprot id: A0A6J3QXM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

9739:GKAP1
gene id: 9739:GKAP1
uniprot id: A0A2U4BRR2
uniprot id: A0A2U4BRS2
uniprot id: A0A2U4BRT0
names: Similarity
messages: Belongs to the GKAP1 family.

9739:LOC101316396
gene id: 9739:LOC101316396
uniprot id: A0A2U3V504
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

9739:CRPPA
gene id: 9739:CRPPA
uniprot id: A0A2U4ARW5
uniprot id: A0A2U4ARX5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Homodimer.
messages: cytosol

9739:FOLR2
gene id: 9739:FOLR2
uniprot id: A0A2U4BPN7
names: Similarity
messages: Belongs to the folate receptor family.

9739:YWHAZ
gene id: 9739:YWHAZ
uniprot id: A0A2U4AHZ7
uniprot id: A0A2U4AI77
names: Similarity
messages: Belongs to the 14-3-3 family.

9739:SLC22A18
gene id: 9739:SLC22A18
uniprot id: A0A6J3RRH7
uniprot id: A0A6J3RRI2
uniprot id: A0A6J3RRJ3
uniprot id: A0A6J3RRK0
uniprot id: A0A6J3RRK5
uniprot id: A0A6J3RRL0
uniprot id: A0A6J3RRR9
uniprot id: A0A6J3RRS2
uniprot id: A0A6J3RRS7
uniprot id: A0A6J3RRT1
uniprot id: A0A6J3RRT5
uniprot id: A0A6J3RRU0
uniprot id: A0A6J3RS19
uniprot id: A0A6J3RS33
uniprot id: A0A6J3RS37
uniprot id: A0A6J3RS42
uniprot id: A0A6J3RS48
uniprot id: A0A6J3RS52
uniprot id: A0A6J3RSB4
uniprot id: A0A6J3RSB9
uniprot id: A0A6J3RSC4
uniprot id: A0A6J3RSC8
uniprot id: A0A6J3RSD2
uniprot id: A0A6J3RSE1
uniprot id: A0A6J3RSF1
uniprot id: A0A6J3RSG1
uniprot id: A0A6J3RSG6
uniprot id: A0A6J3RSH0
uniprot id: A0A6J3RSH9
names: Subcellular Location Annotation
messages: Membrane

9739:STAG2
gene id: 9739:STAG2
uniprot id: A0A6J3QU50
uniprot id: A0A6J3QUS3
uniprot id: A0A6J3QV23
uniprot id: A0A6J3QVU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

9739:TGFBI
gene id: 9739:TGFBI
uniprot id: A0A6J3R2V4
names: Subcellular Location Annotation
messages: extracellular matrix

9739:LOC101338416
gene id: 9739:LOC101338416
uniprot id: A0A6J3RYJ0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

9739:REEP1
gene id: 9739:REEP1
uniprot id: A0A2U4BX45
uniprot id: A0A2U4BX47
uniprot id: A0A2U4BX49
uniprot id: A0A2U4BX53
uniprot id: A0A2U4BX98
uniprot id: A0A2U4BXA3
uniprot id: A0A2U4BXB0
uniprot id: A0A6J3PXP9
uniprot id: A0A6J3PXR9
uniprot id: A0A6J3PXT3
uniprot id: A0A6J3PXZ2
uniprot id: A0A6J3PY93
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:EFNB2
gene id: 9739:EFNB2
uniprot id: A0A2U3V051
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:ALG14
gene id: 9739:ALG14
uniprot id: A0A2U4A1K4
uniprot id: A0A2U4A1K5
uniprot id: A0A2U4A1K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG14 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane

9739:LOC117308646
gene id: 9739:LOC117308646
uniprot id: A0A6J3Q9E8
names: Subcellular Location Annotation
messages: Membrane

9739:STEAP3
gene id: 9739:STEAP3
uniprot id: A0A2U4B2K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

9739:OVCA2
gene id: 9739:OVCA2
uniprot id: A0A2U3V5K3
names: Similarity
messages: Belongs to the LovG family.

9739:PRDM16
gene id: 9739:PRDM16
uniprot id: A0A6J3QDX9
uniprot id: A0A6J3QDY9
names: Subcellular Location Annotation
messages: Nucleus

9739:DDX42
gene id: 9739:DDX42
uniprot id: A0A2U4C389
names: Similarity
messages: Belongs to the DEAD box helicase family.

9739:VGLL1
gene id: 9739:VGLL1
uniprot id: A0A2U3V669
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.
messages: Nucleus

9739:ENO2
gene id: 9739:ENO2
uniprot id: A0A6J3S7R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

9739:STAMBP
gene id: 9739:STAMBP
uniprot id: A0A6J3PVF0
names: Similarity
messages: Belongs to the peptidase M67C family.

9739:JRK
gene id: 9739:JRK
uniprot id: A0A6J3Q865
names: Subcellular Location Annotation
messages: Nucleus

9739:CILP2
gene id: 9739:CILP2
uniprot id: A0A6J3R9D3
uniprot id: A0A6J3RB53
names: Subcellular Location Annotation
messages: extracellular matrix

9739:AUH
gene id: 9739:AUH
uniprot id: A0A2U4BF62
uniprot id: A0A2U4BF70
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

9739:LOC109552667
gene id: 9739:LOC109552667
uniprot id: A0A6J3QZC3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
messages: Interacts with NFS1.
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.

9739:ACE
gene id: 9739:ACE
uniprot id: A0A2U4C3T3
uniprot id: A0A6J3QMS6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M2 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.

9739:LOC101322111
gene id: 9739:LOC101322111
uniprot id: A0A2U4BNB7
uniprot id: A0A2U4BNH9
uniprot id: A0A6J3RLS4
uniprot id: A0A6J3RM56
uniprot id: A0A6J3RN46
uniprot id: A0A6J3RNF5
names: Similarity
messages: Belongs to the cytochrome P450 family.

9739:IDO2
gene id: 9739:IDO2
uniprot id: A0A2U3UYH6
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

9739:UGGT2
gene id: 9739:UGGT2
uniprot id: A0A6J3QB10
uniprot id: A0A6J3QBB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 8 family.
messages: Endoplasmic reticulum lumen

9739:CENPI
gene id: 9739:CENPI
uniprot id: A0A2U4B3L1
uniprot id: A0A6J3QT18
uniprot id: A0A6J3QU11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-I/CTF3 family.
messages: Nucleus
messages: centromere

9739:SPO11
gene id: 9739:SPO11
uniprot id: A0A2U4C1F9
uniprot id: A0A2U4C1K2
names: Similarity
messages: Belongs to the TOP6A family.

9739:RETNLB
gene id: 9739:RETNLB
uniprot id: A0A6J3R8L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistin/FIZZ family.
messages: Secreted

9739:B4GALT7
gene id: 9739:B4GALT7
uniprot id: A0A2U3V0V7
uniprot id: A0A2U4BYV6
uniprot id: A0A2U4BYW8
uniprot id: A0A2U4BZ18
uniprot id: A0A6J3R4A3
uniprot id: A0A6J3R4P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

9739:BABAM2
gene id: 9739:BABAM2
uniprot id: A0A2U4BZJ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BABAM2 family.
messages: Component of the ARISC complex. Component of the BRCA1-A complex. Component of the BRISC complex. Binds polyubiquitin.
messages: Contains 2 ubiquitin-conjugating enzyme family-like (UEV-like) regions. These regions lack the critical Cys residues required for ubiquitination but retain the ability to bind ubiquitin.
messages: Cytoplasm
messages: May play a role in homeostasis or cellular differentiation in cells of neural, epithelial and germline origins. May also act as a death receptor-associated anti-apoptotic protein, which inhibits the mitochondrial apoptotic pathway.
messages: Nucleus

9739:LOC101328382
gene id: 9739:LOC101328382
uniprot id: A0A2U3V4X1
uniprot id: A0A2U4A1N8
uniprot id: A0A2U4A1P5
uniprot id: A0A2U4A1P6
uniprot id: A0A2U4A1Q0
uniprot id: A0A2U4A2L3
uniprot id: A0A2U4A2L7
uniprot id: A0A2U4A2M1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

9739:GPX4
gene id: 9739:GPX4
uniprot id: A0A6J3R7P8
uniprot id: A0A6J3R7V1
names: Similarity
messages: Belongs to the glutathione peroxidase family.

9739:NPB
gene id: 9739:NPB
uniprot id: A0A2U4BT41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuropeptide B/W family.
messages: Secreted

9739:GAPVD1
gene id: 9739:GAPVD1
uniprot id: A0A2U4CH77
uniprot id: A0A2U4CH81
uniprot id: A0A2U4CH83
uniprot id: A0A2U4CH94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GAPVD1 family.
messages: Membrane

9739:TNFRSF11A
gene id: 9739:TNFRSF11A
uniprot id: A0A2U4BHP5
uniprot id: A0A2U4BHR3
uniprot id: A0A2U4BI36
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:ACSF2
gene id: 9739:ACSF2
uniprot id: A0A6J3QM27
uniprot id: A0A6J3QM50
uniprot id: A0A6J3QMK5
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

9739:RABEP1
gene id: 9739:RABEP1
uniprot id: A0A2U4AN35
uniprot id: A0A2U4ANH5
uniprot id: A0A6J3QJH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rabaptin family.
messages: Cytoplasm
messages: Early endosome
messages: Endosome

9739:DPYSL3
gene id: 9739:DPYSL3
uniprot id: A0A2U4AGV9
uniprot id: A0A2U4AHC3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

9739:CRIPT
gene id: 9739:CRIPT
uniprot id: A0A2U3VA96
uniprot id: A0A6J3PWY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRIPT family.
messages: Cytoplasm

9739:MNAT1
gene id: 9739:MNAT1
uniprot id: A0A2U4ADA1
uniprot id: A0A6J3QYP4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with CDK7 and cyclin H.
messages: Nucleus
messages: Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.

9739:NDUFA1
gene id: 9739:NDUFA1
uniprot id: A0A2U4CI31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9739:ATP5PB
gene id: 9739:ATP5PB
uniprot id: A0A2U3V8Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ATPase B chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion
messages: Mitochondrion inner membrane

9739:ARRB2
gene id: 9739:ARRB2
uniprot id: A0A6J3QLR5
uniprot id: A0A6J3QLV7
uniprot id: A0A6J3QMG4
names: Similarity
messages: Belongs to the arrestin family.

9739:PNOC
gene id: 9739:PNOC
uniprot id: A0A2U3V2W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Secreted

9739:STX5
gene id: 9739:STX5
uniprot id: A0A2U3V2L5
uniprot id: A0A2U4B4N2
uniprot id: A0A2U4B4S8
names: Similarity
messages: Belongs to the syntaxin family.

9739:SDHD
gene id: 9739:SDHD
uniprot id: A0A2U3V1P8
uniprot id: A0A2U4BW69
uniprot id: A0A2U4BWD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CybS family.
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

9739:PHACTR4
gene id: 9739:PHACTR4
uniprot id: A0A2U4BKY3
uniprot id: A0A2U4BKZ5
uniprot id: A0A2U4BL34
uniprot id: A0A6J3PZJ7
uniprot id: A0A6J3PZQ5
uniprot id: A0A6J3PZW8
uniprot id: A0A6J3PZX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.
messages: Cytoplasm
messages: Regulator of protein phosphatase 1 (PP1) required for neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development. Acts as an activator of PP1. During neural tube closure, localizes to the ventral neural tube and activates PP1, leading to down-regulate cell proliferation within cranial neural tissue and the neural retina. Also acts as a regulator of migration of enteric neural crest cells (ENCCs) by activating PP1, leading to repression of the integrin signaling through the rho/rock pathway.
messages: lamellipodium

9739:SDE2
gene id: 9739:SDE2
uniprot id: A0A2U3V7H8
uniprot id: A0A2U4A564
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDE2 family.
messages: Cytoplasm
messages: Nucleus

9739:LOC101329851
gene id: 9739:LOC101329851
uniprot id: A0A6J3RIB3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

9739:LOC101338610
gene id: 9739:LOC101338610
uniprot id: A0A2U3V6M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIII family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

9739:TRPV1
gene id: 9739:TRPV1
uniprot id: A0A2U4ANA0
uniprot id: A0A2U4ANA1
uniprot id: A0A2U4ANA4
uniprot id: A0A2U4AND1
uniprot id: A0A2U4ANP6
names: Subcellular Location Annotation
messages: Membrane

9739:CAMK1D
gene id: 9739:CAMK1D
uniprot id: A0A2U4B6J6
uniprot id: A0A6J3R1A7
names: Similarity
messages: Belongs to the protein kinase superfamily.

9739:POLH
gene id: 9739:POLH
uniprot id: A0A2U3V1B3
uniprot id: A0A2U4CIL0
uniprot id: A0A2U4CIL6
uniprot id: A0A2U4CIM3
uniprot id: A0A6J3S0P7
names: Subcellular Location Annotation
messages: Nucleus

9739:SEMA4D
gene id: 9739:SEMA4D
uniprot id: A0A2U4BF53
uniprot id: A0A2U4BF78
uniprot id: A0A2U4BF87
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:ANKH
gene id: 9739:ANKH
uniprot id: A0A2U4CMD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKH family.
messages: Membrane
messages: Regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter.

9739:MMS22L
gene id: 9739:MMS22L
uniprot id: A0A2U4AVL0
uniprot id: A0A6J3S8S1
uniprot id: A0A6J3SAD0
uniprot id: A0A6J3SAE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MMS22 family. MMS22L subfamily.
messages: Chromosome
messages: Nucleus

9739:KCNB1
gene id: 9739:KCNB1
uniprot id: A0A6J3Q3X9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

9739:RARS1
gene id: 9739:RARS1
uniprot id: A0A2U3V1D5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9739:MINPP1
gene id: 9739:MINPP1
uniprot id: A0A2U4BK52
uniprot id: A0A2U4BKC8
names: Similarity
messages: Belongs to the histidine acid phosphatase family. MINPP1 subfamily.

9739:LOC117307711
gene id: 9739:LOC117307711
uniprot id: A0A6J3PU76
uniprot id: A0A6J3PUN2
uniprot id: A0A6J3PV48
names: Similarity
messages: Belongs to the serpin family.
messages: Belongs to the serpin family. Ov-serpin subfamily.

9739:LOC101334328
gene id: 9739:LOC101334328
uniprot id: A0A2U3V107
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

9739:LOC101315861
gene id: 9739:LOC101315861
uniprot id: A0A6J3PV18
names: Similarity
messages: Belongs to the VPS26 family.

9739:DZIP1
gene id: 9739:DZIP1
uniprot id: A0A6J3QA31
uniprot id: A0A6J3QA85
uniprot id: A0A6J3QA90
uniprot id: A0A6J3QAN5
uniprot id: A0A6J3QAP0
uniprot id: A0A6J3QAZ8
uniprot id: A0A6J3QB04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DZIP C2H2-type zinc-finger protein family.
messages: cilium basal body

9739:EIF1AX
gene id: 9739:EIF1AX
uniprot id: A0A2U4AQK7
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Component of the 43S pre-initiation complex (43S PIC), which binds to the mRNA cap-proximal region, scans mRNA 5'-untranslated region, and locates the initiation codon. This protein enhances formation of the cap-proximal complex. Together with EIF1, facilitates scanning, start codon recognition, promotion of the assembly of 48S complex at the initiation codon (43S PIC becomes 48S PIC after the start codon is reached), and dissociation of aberrant complexes. After start codon location, together with EIF5B orients the initiator methionine-tRNA in a conformation that allows 60S ribosomal subunit joining to form the 80S initiation complex. Is released after 80S initiation complex formation, just after GTP hydrolysis by EIF5B, and before release of EIF5B. Its globular part is located in the A site of the 40S ribosomal subunit. Its interaction with EIF5 during scanning contribute to the maintenance of EIF1 within the open 43S PIC. In contrast to yeast orthologs, does not bind EIF1.

9739:DDX1
gene id: 9739:DDX1
uniprot id: A0A2U4C065
uniprot id: A0A2U4C066
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX1 subfamily.
messages: Cytoplasmic granule
messages: RNA helicase.
messages: The helicase domain is involved in the stimulation of RELA transcriptional activity.

9739:SDHAF1
gene id: 9739:SDHAF1
uniprot id: A0A2U3V7S3
names: Similarity
messages: Belongs to the complex I LYR family. SDHAF1 subfamily.

9739:ADGRE1
gene id: 9739:ADGRE1
uniprot id: A0A6J3R7H5
uniprot id: A0A6J3R9B0
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:CHMP4C
gene id: 9739:CHMP4C
uniprot id: A0A2U3V973
names: Similarity
messages: Belongs to the SNF7 family.

9739:GPR21
gene id: 9739:GPR21
uniprot id: A0A2U4CH24
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9739:HNF1B
gene id: 9739:HNF1B
uniprot id: A0A2U4C618
uniprot id: A0A2U4C621
uniprot id: A0A2U4C631
uniprot id: A0A2U4C6B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HNF1 homeobox family.
messages: Nucleus

9739:SUGP2
gene id: 9739:SUGP2
uniprot id: A0A6J3R549
uniprot id: A0A6J3R7U2
names: Subcellular Location Annotation
messages: Nucleus

9739:FIBIN
gene id: 9739:FIBIN
uniprot id: A0A2U3V6M8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FIBIN family.
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer; disulfide-linked. Seems to also exist as monomers.
messages: Secreted

9739:HTR3B
gene id: 9739:HTR3B
uniprot id: A0A2U4BWJ1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9739:ARID3B
gene id: 9739:ARID3B
uniprot id: A0A6J3QZF6
uniprot id: A0A6J3QZQ9
uniprot id: A0A6J3R066
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer.
messages: Nucleus
messages: Transcription factor.

9739:LOC101329698
gene id: 9739:LOC101329698
uniprot id: A0A6J3QTN7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

9739:RIBC2
gene id: 9739:RIBC2
uniprot id: A0A2U4C5J5
names: Similarity
messages: Belongs to the RIB43A family.

9739:MRPS5
gene id: 9739:MRPS5
uniprot id: A0A2U3UZU4
uniprot id: A0A2U4B0B0
uniprot id: A0A2U4B0P9
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

9739:LOC117311186
gene id: 9739:LOC117311186
uniprot id: A0A6J3R1K9
names: Similarity
messages: Belongs to the TMA7 family.

9739:KLHL3
gene id: 9739:KLHL3
uniprot id: A0A6J3R2V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KLHL3 family.
messages: cytoskeleton
messages: cytosol

9739:ST6GALNAC1
gene id: 9739:ST6GALNAC1
uniprot id: A0A6J3QQ87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9739:ACKR1
gene id: 9739:ACKR1
uniprot id: A0A6J3RCV2
uniprot id: A0A6J3RDI0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine-binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for chemokines including CCL2, CCL5, CCL7, CCL11, CCL13, CCL14, CCL17, CXCL5, CXCL6, IL8/CXCL8, CXCL11, GRO, RANTES, MCP-1 and TARC. May regulate chemokine bioavailability and, consequently, leukocyte recruitment through two distinct mechanisms: when expressed in endothelial cells, it sustains the abluminal to luminal transcytosis of tissue-derived chemokines and their subsequent presentation to circulating leukocytes; when expressed in erythrocytes, serves as blood reservoir of cognate chemokines but also as a chemokine sink, buffering potential surges in plasma chemokine levels.
messages: Belongs to the G-protein coupled receptor 1 family. Atypical chemokine receptor subfamily.
messages: Early endosome
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Recycling endosome

9739:ANXA4
gene id: 9739:ANXA4
uniprot id: A0A2U4BYX2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Zymogen granule membrane

9739:FOXK1
gene id: 9739:FOXK1
uniprot id: A0A2U4CBY2
uniprot id: A0A6J3Q3K4
names: Subcellular Location Annotation
messages: Nucleus

9739:DTX2
gene id: 9739:DTX2
uniprot id: A0A6J3PYD0
uniprot id: A0A6J3PYL7
uniprot id: A0A6J3PYX5
uniprot id: A0A6J3PYY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

9739:TMEM121B
gene id: 9739:TMEM121B
uniprot id: A0A2U4AKU8
names: Similarity
messages: Belongs to the TMEM121 family.

9739:GABRA5
gene id: 9739:GABRA5
uniprot id: A0A6J3R230
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9739:LOC109552384
gene id: 9739:LOC109552384
uniprot id: A0A6J3RH91
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9739:VPS26C
gene id: 9739:VPS26C
uniprot id: A0A6J3RB25
uniprot id: A0A6J3RBJ8
uniprot id: A0A6J3RBT3
uniprot id: A0A6J3RDH5
names: Similarity
messages: Belongs to the VPS26 family.

9739:ACSS1
gene id: 9739:ACSS1
uniprot id: A0A6J3Q3J8
uniprot id: A0A6J3Q3T7
uniprot id: A0A6J3Q4B6
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

9739:MSN
gene id: 9739:MSN
uniprot id: A0A2U4CGI1
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton
messages: microvillus

9739:PAX1
gene id: 9739:PAX1
uniprot id: A0A6J3Q352
names: Subcellular Location Annotation
messages: Nucleus

9739:FAM241B
gene id: 9739:FAM241B
uniprot id: A0A2U3V7L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM241 family.
messages: Membrane

9739:ADAM12
gene id: 9739:ADAM12
uniprot id: A0A2U4BRG7
uniprot id: A0A6J3Q5Z6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:COG2
gene id: 9739:COG2
uniprot id: A0A6J3Q7T2
uniprot id: A0A6J3Q7T8
uniprot id: A0A6J3Q876
uniprot id: A0A6J3Q881
uniprot id: A0A6J3Q8L5
names: Similarity
messages: Belongs to the COG2 family.

9739:ACTL9
gene id: 9739:ACTL9
uniprot id: A0A2U3V473
names: Similarity
messages: Belongs to the actin family.

9739:ACHE
gene id: 9739:ACHE
uniprot id: A0A6J3PZD5
uniprot id: A0A6J3PZJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Secreted

9739:MYRFL
gene id: 9739:MYRFL
uniprot id: A0A2U4CQP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRF family.
messages: Membrane

9739:KRT8
gene id: 9739:KRT8
uniprot id: A0A6J3S7M7
names: Similarity
messages: Belongs to the intermediate filament family.

9739:NUF2
gene id: 9739:NUF2
uniprot id: A0A2U4B327
names: Similarity
messages: Belongs to the NUF2 family.

9739:MINAR1
gene id: 9739:MINAR1
uniprot id: A0A2U4C7W3
names: Similarity
messages: Belongs to the MINAR family.

9739:HMX1
gene id: 9739:HMX1
uniprot id: A0A6J3RCG4
names: Subcellular Location Annotation
messages: Nucleus

9739:CTC1
gene id: 9739:CTC1
uniprot id: A0A2U4C2Y6
uniprot id: A0A6J3QKI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTC1 family.
messages: Nucleus
messages: telomere

9739:LOC117309563
gene id: 9739:LOC117309563
uniprot id: A0A6J3QMC1
names: Similarity
messages: Belongs to the intermediate filament family.

9739:EBPL
gene id: 9739:EBPL
uniprot id: A0A2U4BG36
uniprot id: A0A2U4BG37
uniprot id: A0A2U4BG73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:ERF
gene id: 9739:ERF
uniprot id: A0A6J3QDA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9739:SRP14
gene id: 9739:SRP14
uniprot id: A0A2U3V2Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP14 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm
messages: Heterodimer with SRP9; binds RNA as heterodimer. Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.

9739:LOC117310131
gene id: 9739:LOC117310131
uniprot id: A0A6J3QRK5
names: Similarity
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.

9739:GDF2
gene id: 9739:GDF2
uniprot id: A0A2U3V4B9
names: Similarity
messages: Belongs to the TGF-beta family.

9739:GRIN3B
gene id: 9739:GRIN3B
uniprot id: A0A6J3RAM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

9739:MED13
gene id: 9739:MED13
uniprot id: A0A2U4C682
uniprot id: A0A2U4C694
uniprot id: A0A2U4C6H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

9739:PCLAF
gene id: 9739:PCLAF
uniprot id: A0A2U3V6F7
names: Subcellular Location Annotation
messages: Nucleus
messages: perinuclear region

9739:LOC101325546
gene id: 9739:LOC101325546
uniprot id: A0A6J3S7F9
uniprot id: A0A6J3S816
names: Similarity
messages: Belongs to the cytochrome P450 family.

9739:CPSF4L
gene id: 9739:CPSF4L
uniprot id: A0A6J3QLE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex.
messages: Nucleus

9739:PRDM13
gene id: 9739:PRDM13
uniprot id: A0A2U3V0U9
names: Subcellular Location Annotation
messages: Nucleus

9739:SLC2A8
gene id: 9739:SLC2A8
uniprot id: A0A6J3RIE1
uniprot id: A0A6J3RIM5
uniprot id: A0A6J3RIP9
uniprot id: A0A6J3RKE0
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

9739:LOC109550414
gene id: 9739:LOC109550414
uniprot id: A0A2U4BKJ9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

9739:IGFBP3
gene id: 9739:IGFBP3
uniprot id: A0A2U3VAN3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9739:GATA6
gene id: 9739:GATA6
uniprot id: A0A6J3PV03
names: Subcellular Location Annotation
messages: Nucleus

9739:VPS35L
gene id: 9739:VPS35L
uniprot id: A0A6J3Q2H3
uniprot id: A0A6J3Q2I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS35L family.
messages: Endosome

9739:LOC109549216
gene id: 9739:LOC109549216
uniprot id: A0A6J3Q0Z7
names: Subcellular Location Annotation
messages: Membrane

9739:LSM8
gene id: 9739:LSM8
uniprot id: A0A2U3V760
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.

9739:RPS6KA2
gene id: 9739:RPS6KA2
uniprot id: A0A6J3S9Y2
uniprot id: A0A6J3SAE3
uniprot id: A0A6J3SB44
uniprot id: A0A6J3SB69
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

9739:VEPH1
gene id: 9739:VEPH1
uniprot id: A0A2U4C8W3
names: Similarity
messages: Belongs to the MELT/VEPH family.

9739:LOC117309121
gene id: 9739:LOC117309121
uniprot id: A0A6J3QG67
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

9739:PTPRN
gene id: 9739:PTPRN
uniprot id: A0A6J3RL88
uniprot id: A0A6J3RLX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily.
messages: Membrane
messages: secretory vesicle membrane

9739:TIPARP
gene id: 9739:TIPARP
uniprot id: A0A2U3V3R3
uniprot id: A0A2U4C8Q0
names: Similarity
messages: Belongs to the ARTD/PARP family.

9739:MORF4L1
gene id: 9739:MORF4L1
uniprot id: A0A2U3V2X9
uniprot id: A0A2U3V339
uniprot id: A0A2U4C7C2
names: Subcellular Location Annotation
messages: Nucleus

9739:UCMA
gene id: 9739:UCMA
uniprot id: A0A6J3R2W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UCMA family.
messages: May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface.
messages: extracellular matrix

9739:CRKL
gene id: 9739:CRKL
uniprot id: A0A2U4ALB4
names: Similarity
messages: Belongs to the CRK family.

9739:HOXA2
gene id: 9739:HOXA2
uniprot id: A0A6J3RXD8
names: Subcellular Location Annotation
messages: Nucleus

9739:CCT7
gene id: 9739:CCT7
uniprot id: A0A2U3UZ56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.

9739:DCBLD2
gene id: 9739:DCBLD2
uniprot id: A0A2U4ABA3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:RFC5
gene id: 9739:RFC5
uniprot id: A0A2U3UZ58
names: Similarity
messages: Belongs to the activator 1 small subunits family.

9739:PROKR2
gene id: 9739:PROKR2
uniprot id: A0A2U3V8S7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9739:SLC25A44
gene id: 9739:SLC25A44
uniprot id: A0A2U3UZQ6
uniprot id: A0A2U4B6P6
uniprot id: A0A6J3RE97
uniprot id: A0A6J3REV1
uniprot id: A0A6J3RF42
uniprot id: A0A6J3RGL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Nucleus
messages: kinetochore

9739:SOAT2
gene id: 9739:SOAT2
uniprot id: A0A6J3S7X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:JOSD1
gene id: 9739:JOSD1
uniprot id: A0A6J3S5V9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:SYT14
gene id: 9739:SYT14
uniprot id: A0A2U4A017
uniprot id: A0A2U4A0Z3
names: Similarity
messages: Belongs to the synaptotagmin family.

9739:EIF6
gene id: 9739:EIF6
uniprot id: A0A6J3Q2K8
uniprot id: A0A6J3Q2L3
uniprot id: A0A6J3Q2V7
uniprot id: A0A6J3Q3A8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-6 family.
messages: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)-dependent protein kinase C activity. In tissues responsive to insulin, controls fatty acid synthesis and glycolysis by exerting translational control of adipogenic transcription factors such as CEBPB, CEBPD and ATF4 that have G/C rich or uORF in their 5'UTR. Required for ROS-dependent megakaryocyte maturation and platelets formation, controls the expression of mitochondrial respiratory chain genes involved in reactive oxygen species (ROS) synthesis. Involved in miRNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC. Modulates cell cycle progression and global translation of pre-B cells, its activation seems to be rate-limiting in tumorigenesis and tumor growth.
messages: Cytoplasm
messages: Monomer. Associates with the 60S ribosomal subunit. Interacts with RACK1. Interacts with DICER1, AGO2, TARBP2, MOV10 and RPL7A; they form a large RNA-induced silencing complex (RISC).
messages: Phosphorylation at Ser-186 and Ser-187 promotes nuclear export.
messages: Phosphorylation at Ser-216 and Ser-217 promotes nuclear export.
messages: Phosphorylation at Ser-244 and Ser-245 promotes nuclear export.
messages: Phosphorylation at Ser-258 and Ser-259 promotes nuclear export.
messages: nucleolus

9739:COQ2
gene id: 9739:COQ2
uniprot id: A0A2U4B5R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
messages: Mitochondrion inner membrane

9739:CNTNAP5
gene id: 9739:CNTNAP5
uniprot id: A0A2U4B286
uniprot id: A0A6J3RPG7
names: Caution
names: Similarity
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:FAM120C
gene id: 9739:FAM120C
uniprot id: A0A2U4C0Y0
uniprot id: A0A2U4C0Y5
uniprot id: A0A2U4C0Z0
uniprot id: A0A2U4C0Z4
uniprot id: A0A2U4C0Z9
uniprot id: A0A2U4C113
uniprot id: A0A2U4C123
uniprot id: A0A2U4C133
uniprot id: A0A2U4C138
uniprot id: A0A2U4C143
uniprot id: A0A2U4C166
uniprot id: A0A2U4C172
uniprot id: A0A2U4C177
uniprot id: A0A6J3QU42
uniprot id: A0A6J3QUJ8
uniprot id: A0A6J3QUK2
uniprot id: A0A6J3QUR4
uniprot id: A0A6J3QUR8
uniprot id: A0A6J3QV10
uniprot id: A0A6J3QVS8
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

9739:LOC117309576
gene id: 9739:LOC117309576
uniprot id: A0A6J3QMN5
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

9739:NEMP1
gene id: 9739:NEMP1
uniprot id: A0A2U3V0K2
uniprot id: A0A2U3ZZL2
uniprot id: A0A2U4A0I0
uniprot id: A0A6J3S5Q3
uniprot id: A0A6J3S709
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NEMP family.
messages: Nucleus inner membrane

9739:ACADS
gene id: 9739:ACADS
uniprot id: A0A6J3PSJ5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

9739:MARCHF4
gene id: 9739:MARCHF4
uniprot id: A0A2U4BMJ8
names: Subcellular Location Annotation
messages: Membrane

9739:EEF1AKMT2
gene id: 9739:EEF1AKMT2
uniprot id: A0A6J3Q7H1
uniprot id: A0A6J3Q897
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.
messages: Cytoplasm
messages: Nucleus
messages: Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'.

9739:GPX1
gene id: 9739:GPX1
uniprot id: A0A2U3VAH2
names: Similarity
messages: Belongs to the glutathione peroxidase family.

9739:ENTPD7
gene id: 9739:ENTPD7
uniprot id: A0A2U4BQ61
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

9739:RHCG
gene id: 9739:RHCG
uniprot id: A0A6J3R235
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

9739:LOC109547721
gene id: 9739:LOC109547721
uniprot id: A0A6J3Q406
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

9739:MEGF6
gene id: 9739:MEGF6
uniprot id: A0A6J3QEC4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:EID1
gene id: 9739:EID1
uniprot id: A0A2U4AUT9
names: Subcellular Location Annotation
messages: Nucleus

9739:LOC101324213
gene id: 9739:LOC101324213
uniprot id: A0A6J3R805
names: Subcellular Location Annotation
messages: Nucleus

9739:CSNK1D
gene id: 9739:CSNK1D
uniprot id: A0A6J3QLM8
uniprot id: A0A6J3QM95
uniprot id: A0A6J3QMC5
names: Similarity
messages: Belongs to the protein kinase superfamily.

9739:ZSCAN10
gene id: 9739:ZSCAN10
uniprot id: A0A2U4BXJ8
names: Subcellular Location Annotation
messages: Nucleus

9739:PUS1
gene id: 9739:PUS1
uniprot id: A0A6J3PRI1
uniprot id: A0A6J3PRM6
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

9739:PRLHR
gene id: 9739:PRLHR
uniprot id: A0A2U3V2L2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9739:RPL7L1
gene id: 9739:RPL7L1
uniprot id: A0A2U3V6C6
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

9739:IRX1
gene id: 9739:IRX1
uniprot id: A0A6J3R2D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

9739:DNAJB12
gene id: 9739:DNAJB12
uniprot id: A0A6J3Q5M1
uniprot id: A0A6J3Q5V5
uniprot id: A0A6J3Q5Y7
uniprot id: A0A6J3Q646
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:EGF
gene id: 9739:EGF
uniprot id: A0A2U4ARM7
uniprot id: A0A2U4ARN0
uniprot id: A0A2U4ARN4
uniprot id: A0A2U4AS42
uniprot id: A0A6J3RFG7
names: Caution
names: Function
names: Subunit
messages: EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.
messages: Interacts with EGFR and promotes EGFR dimerization.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:LOC101331517
gene id: 9739:LOC101331517
uniprot id: A0A2U3V8H8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flavin monoamine oxidase family.
messages: Mitochondrion outer membrane
messages: Monomer, homo- or heterodimer (containing two subunits of similar size). Each subunit contains a covalently bound flavin. Enzymatically active as monomer.

9739:MGRN1
gene id: 9739:MGRN1
uniprot id: A0A6J3PYG2
uniprot id: A0A6J3PYI4
uniprot id: A0A6J3PYL9
uniprot id: A0A6J3PYM5
uniprot id: A0A6J3PYS4
uniprot id: A0A6J3PZ36
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin ligase.

9739:DPPA4
gene id: 9739:DPPA4
uniprot id: A0A6J3RBP6
names: Subcellular Location Annotation
messages: Nucleus

9739:CD3E
gene id: 9739:CD3E
uniprot id: A0A2U4BW43
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9739:TMBIM4
gene id: 9739:TMBIM4
uniprot id: A0A2U3V6C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

9739:ALDH7A1
gene id: 9739:ALDH7A1
uniprot id: A0A2U4AFX6
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

9739:HHIPL2
gene id: 9739:HHIPL2
uniprot id: A0A6J3QLY6
names: Similarity
messages: Belongs to the HHIP family.

9739:SATB2
gene id: 9739:SATB2
uniprot id: A0A2U4BNH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

9739:MTG2
gene id: 9739:MTG2
uniprot id: A0A2U4C2C4
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

9739:HBP1
gene id: 9739:HBP1
uniprot id: A0A2U3V690
uniprot id: A0A2U4BSH2
uniprot id: A0A2U4BSH8
uniprot id: A0A2U4BSP0
uniprot id: A0A6J3RW76
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

9739:PDE7B
gene id: 9739:PDE7B
uniprot id: A0A2U3V1M5
uniprot id: A0A6J3S9K5
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9739:SLC30A7
gene id: 9739:SLC30A7
uniprot id: A0A2U3V032
uniprot id: A0A2U4A285
uniprot id: A0A2U4A288
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Functions as a zinc transporter.
messages: Homooligomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: trans-Golgi network membrane

9739:DMRT1
gene id: 9739:DMRT1
uniprot id: A0A2U4BB50
uniprot id: A0A6J3RHD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

9739:LCOR
gene id: 9739:LCOR
uniprot id: A0A2U4BPZ0
uniprot id: A0A2U4BPZ7
uniprot id: A0A2U4BPZ9
uniprot id: A0A2U4BQB1
names: Subcellular Location Annotation
messages: Nucleus

9739:CIBAR2
gene id: 9739:CIBAR2
uniprot id: A0A6J3QEZ7
names: Subcellular Location Annotation
messages: centriole
messages: cilium basal body

9739:SGSM1
gene id: 9739:SGSM1
uniprot id: A0A2U3V6P7
names: Similarity
messages: Belongs to the RUTBC family.

9739:LOC117313392
gene id: 9739:LOC117313392
uniprot id: A0A6J3QYX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NUSAP family.
messages: Cytoplasm

9739:TMEM120A
gene id: 9739:TMEM120A
uniprot id: A0A6J3Q0G0
uniprot id: A0A6J3Q0Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM120 family.
messages: Membrane
messages: Nucleus inner membrane

9739:HAPLN4
gene id: 9739:HAPLN4
uniprot id: A0A6J3R8Q4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9739:SRC
gene id: 9739:SRC
uniprot id: A0A6J3Q1J9
uniprot id: A0A6J3Q1K3
uniprot id: A0A6J3Q1K4
uniprot id: A0A6J3Q1V1
uniprot id: A0A6J3Q262
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

9739:LOC109551959
gene id: 9739:LOC109551959
uniprot id: A0A2U4C9F5
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

9739:SPECC1L
gene id: 9739:SPECC1L
uniprot id: A0A6J3PSN3
uniprot id: A0A6J3PSU1
uniprot id: A0A6J3PT72
uniprot id: A0A6J3PT82
uniprot id: A0A6J3PTS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytospin-A family.
messages: Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration.
messages: May interact with both microtubules and actin cytoskeleton.
messages: cytoskeleton
messages: gap junction
messages: spindle

9739:SLC11A1
gene id: 9739:SLC11A1
uniprot id: A0A6J3RMS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Macrophage-specific antiporter that fluxes metal ions in either direction against a proton gradient. Localized to late endosomal lysosomal membranes, delivers bivalent cations from the cytosol into these acidic compartments where they may directly affect antimicrobial activity. Involved in iron metabolism and host natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis of its protective enzymes.

9739:GPR155
gene id: 9739:GPR155
uniprot id: A0A2U3V864
uniprot id: A0A2U4ABE0
uniprot id: A0A2U4AC25
names: Subcellular Location Annotation
messages: Membrane

9739:BBS5
gene id: 9739:BBS5
uniprot id: A0A2U3V9C2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BBS5 family.
messages: Membrane
messages: Part of BBSome complex, that contains BBS1, BBS2, BBS4, BBS5, BBS7, BBS8/TTC8, BBS9 and BBIP10.
messages: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for BBSome complex ciliary localization but not for the proper complex assembly.
messages: centriolar satellite
messages: cilium membrane

9739:GABRE
gene id: 9739:GABRE
uniprot id: A0A2U3V8K5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9739:CNTN1
gene id: 9739:CNTN1
uniprot id: A0A2U4BAG7
uniprot id: A0A2U4BAR9
names: Similarity
messages: Belongs to the immunoglobulin superfamily. Contactin family.

9739:SHCBP1L
gene id: 9739:SHCBP1L
uniprot id: A0A2U4A0P8
names: Subcellular Location Annotation
messages: spindle

9739:LYRM4
gene id: 9739:LYRM4
uniprot id: A0A2U4C5N2
uniprot id: A0A2U4C5V2
names: Similarity
messages: Belongs to the complex I LYR family.

9739:LOC101324043
gene id: 9739:LOC101324043
uniprot id: A0A6J3S4M2
names: Subcellular Location Annotation
messages: Nucleus

9739:ZNF263
gene id: 9739:ZNF263
uniprot id: A0A2U3V1K1
uniprot id: A0A2U4C8I3
uniprot id: A0A2U4CAC9
uniprot id: A0A6J3PYK5
names: Subcellular Location Annotation
messages: Nucleus

9739:EPCAM
gene id: 9739:EPCAM
uniprot id: A0A2U3V045
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPCAM family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lateral cell membrane
messages: May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.
messages: Membrane
messages: tight junction

9739:SLC45A3
gene id: 9739:SLC45A3
uniprot id: A0A2U4CR16
names: Subcellular Location Annotation
messages: Membrane

9739:TNFSF4
gene id: 9739:TNFSF4
uniprot id: A0A0U5J6T4
names: Similarity
messages: Belongs to the tumor necrosis factor family.

9739:EPB42
gene id: 9739:EPB42
uniprot id: A0A2U3V3H2
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.

9739:UPF2
gene id: 9739:UPF2
uniprot id: A0A2U4B6H9
names: Subcellular Location Annotation
messages: Cytoplasm

9739:WNT8A
gene id: 9739:WNT8A
uniprot id: A0A2U3V7E0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9739:LOC101333202
gene id: 9739:LOC101333202
uniprot id: A0A2U3V4V9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS10 family.

9739:LOC101337807
gene id: 9739:LOC101337807
uniprot id: A0A6J3S0P3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.

9739:NRG4
gene id: 9739:NRG4
uniprot id: A0A6J3QZV8
names: Caution
names: Similarity
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:ZFP36L2
gene id: 9739:ZFP36L2
uniprot id: A0A2U3V9E3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

9739:TEX261
gene id: 9739:TEX261
uniprot id: A0A2U3V0B7
uniprot id: A0A2U4BZJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVP26 family.
messages: Membrane

9739:IL1R1
gene id: 9739:IL1R1
uniprot id: A0A2U3V627
uniprot id: A0A2U4B0R0
uniprot id: A0A6J3PV70
uniprot id: A0A6J3PVG9
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

9739:LOC101334221
gene id: 9739:LOC101334221
uniprot id: A0A6J3S0I1
names: Function
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.
messages: Metallothioneins have a high content of cysteine residues that bind various heavy metals.

9739:IL18RAP
gene id: 9739:IL18RAP
uniprot id: A0A2U4B0S2
uniprot id: A0A2U4B0T2
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

9739:TGM2
gene id: 9739:TGM2
uniprot id: A0A6J3Q3K3
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

9739:DUSP26
gene id: 9739:DUSP26
uniprot id: A0A6J3QQH6
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

9739:EZR
gene id: 9739:EZR
uniprot id: A0A6J3S9S5
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton
messages: microvillus

9739:LOC101320341
gene id: 9739:LOC101320341
uniprot id: A0A6J3PTC3
names: Similarity
messages: Belongs to the GST superfamily. Theta family.

9739:C13H22orf39
gene id: 9739:C13H22orf39
uniprot id: A0A2U4ALG4
uniprot id: A0A2U4ALU8
names: Similarity
messages: Belongs to the UPF0545 family.

9739:APPL2
gene id: 9739:APPL2
uniprot id: A0A2U4CS55
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: Nucleus
messages: phagosome
messages: ruffle

9739:PSMA8
gene id: 9739:PSMA8
uniprot id: A0A2U4AZ02
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

9739:LOC101337746
gene id: 9739:LOC101337746
uniprot id: A0A6J3PSS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB.

9739:CAVIN3
gene id: 9739:CAVIN3
uniprot id: A0A2U3V9A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

9739:FUT1
gene id: 9739:FUT1
uniprot id: A0A6J3QCQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 11 family.
messages: Golgi stack membrane
messages: Membrane

9739:CUTA
gene id: 9739:CUTA
uniprot id: A0A6J3S0C6
uniprot id: A0A6J3S0X4
names: Similarity
names: Subunit
messages: Belongs to the CutA family.
messages: Homotrimer.

9739:MON2
gene id: 9739:MON2
uniprot id: A0A2U3ZYH8
uniprot id: A0A2U3ZYI6
uniprot id: A0A2U3ZYK2
uniprot id: A0A2U3ZYK6
uniprot id: A0A2U3ZZI8
names: Similarity
messages: Belongs to the MON2 family.

9739:SUCLG1
gene id: 9739:SUCLG1
uniprot id: A0A2U4BX40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterodimer of an alpha and a beta subunit. Different beta subunits determine nucleotide specificity. Together with the ATP-specific beta subunit SUCLA2, forms an ADP-forming succinyl-CoA synthetase (A-SCS). Together with the GTP-specific beta subunit SUCLG2 forms a GDP-forming succinyl-CoA synthetase (G-SCS).
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.

9739:FOXA3
gene id: 9739:FOXA3
uniprot id: A0A6J3QH98
names: Subcellular Location Annotation
messages: Nucleus

9739:CACNA1A
gene id: 9739:CACNA1A
uniprot id: A0A6J3R8Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q-type calcium currents.

9739:LOC101320872
gene id: 9739:LOC101320872
uniprot id: A0A6J3RVA1
names: Similarity
messages: Belongs to the folate receptor family.

9739:SPATA1
gene id: 9739:SPATA1
uniprot id: A0A6J3RZV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST5 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

9739:HDAC2
gene id: 9739:HDAC2
uniprot id: A0A6J3SAI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

9739:OPN4
gene id: 9739:OPN4
uniprot id: A0A6J3Q749
uniprot id: A0A6J3Q7J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

9739:LOC101321510
gene id: 9739:LOC101321510
uniprot id: A0A6J3S6S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPC2 family.
messages: Secreted

9739:RSPO2
gene id: 9739:RSPO2
uniprot id: A0A6J3Q945
names: Similarity
messages: Belongs to the R-spondin family.

9739:MRPL10
gene id: 9739:MRPL10
uniprot id: A0A2U3UZH2
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

9739:LOC109549501
gene id: 9739:LOC109549501
uniprot id: A0A6J3QRE4
names: Similarity
messages: Belongs to the heat shock protein 70 family.

9739:SLC39A4
gene id: 9739:SLC39A4
uniprot id: A0A6J3Q802
names: Subcellular Location Annotation
messages: Membrane

9739:TTC38
gene id: 9739:TTC38
uniprot id: A0A6J3S458
uniprot id: A0A6J3S4G0
names: Similarity
messages: Belongs to the TTC38 family.

9739:SERPINA7
gene id: 9739:SERPINA7
uniprot id: A0A2U3V772
names: Similarity
messages: Belongs to the serpin family.

9739:CCNQ
gene id: 9739:CCNQ
uniprot id: A0A6J3QSN3
uniprot id: A0A6J3QTC3
names: Similarity
messages: Belongs to the cyclin family. Cyclin-like FAM58 subfamily.

9739:LOC117308059
gene id: 9739:LOC117308059
uniprot id: A0A6J3PZH8
names: Subcellular Location Annotation
messages: Membrane

9739:HCST
gene id: 9739:HCST
uniprot id: A0A6J3QFW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAP10 family.
messages: Membrane

9739:BRINP1
gene id: 9739:BRINP1
uniprot id: A0A6J3RKG9
names: Similarity
messages: Belongs to the BRINP family.

9739:FGD3
gene id: 9739:FGD3
uniprot id: A0A6J3RFY7
uniprot id: A0A6J3RG34
uniprot id: A0A6J3RGF4
uniprot id: A0A6J3RGR2
names: Subcellular Location Annotation
messages: cytoskeleton

9739:PCNP
gene id: 9739:PCNP
uniprot id: A0A2U3V6E5
uniprot id: A0A2U4ABU8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with UHRF2/NIRF.
messages: May be involved in cell cycle regulation.
messages: Nucleus

9739:PPM1E
gene id: 9739:PPM1E
uniprot id: A0A6J3QNJ5
names: Similarity
messages: Belongs to the PP2C family.

9739:MMP9
gene id: 9739:MMP9
uniprot id: A0A6J3Q1N9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.
messages: extracellular matrix

9739:TBCCD1
gene id: 9739:TBCCD1
uniprot id: A0A2U4C8H5
uniprot id: A0A2U4C8H6
uniprot id: A0A2U4C8I5
uniprot id: A0A6J3RCA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCC family.
messages: centrosome
messages: spindle pole

9739:PPEF1
gene id: 9739:PPEF1
uniprot id: A0A2U4AQQ3
names: Similarity
messages: Belongs to the PPP phosphatase family.

9739:SNCB
gene id: 9739:SNCB
uniprot id: A0A6J3R3W4
names: Similarity
messages: Belongs to the synuclein family.

9739:TPST2
gene id: 9739:TPST2
uniprot id: A0A2U3VAK8
uniprot id: A0A2U4CJV9
uniprot id: A0A2U4CJW2
uniprot id: A0A2U4CJW6
uniprot id: A0A2U4CK40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein sulfotransferase family.
messages: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
messages: Golgi apparatus membrane

9739:MAP2K6
gene id: 9739:MAP2K6
uniprot id: A0A6J3QLU2
names: Similarity
messages: Belongs to the protein kinase superfamily.

9739:ATP13A5
gene id: 9739:ATP13A5
uniprot id: A0A6J3R9G8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:MALSU1
gene id: 9739:MALSU1
uniprot id: A0A2U4ATH1
names: Similarity
messages: Belongs to the Iojap/RsfS family.

9739:RGN
gene id: 9739:RGN
uniprot id: A0A2U4C0N5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMP-30/CGR1 family.
messages: Cytoplasm
messages: Monomer.

9739:CACNA2D2
gene id: 9739:CACNA2D2
uniprot id: A0A6J3S1Z3
uniprot id: A0A6J3S225
uniprot id: A0A6J3S253
uniprot id: A0A6J3S2R2
uniprot id: A0A6J3S325
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

9739:NUDT21
gene id: 9739:NUDT21
uniprot id: A0A2U3V048
uniprot id: A0A2U4BDR2
uniprot id: A0A2U4BDV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family. CPSF5 subfamily.
messages: Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.
messages: Cytoplasm
messages: Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.
messages: Nucleus

9739:MOG
gene id: 9739:MOG
uniprot id: A0A2U3UYX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Homodimer.
messages: Membrane
messages: Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. Mediates homophilic cell-cell adhesion.

9739:ZC3H12B
gene id: 9739:ZC3H12B
uniprot id: A0A2U4CG87
names: Similarity
messages: Belongs to the ZC3H12 family.

9739:TMC3
gene id: 9739:TMC3
uniprot id: A0A2U4C771
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

9739:LYZL4
gene id: 9739:LYZL4
uniprot id: A0A6J3RYK7
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

9739:SLC19A3
gene id: 9739:SLC19A3
uniprot id: A0A2U3V844
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

9739:SELENBP1
gene id: 9739:SELENBP1
uniprot id: A0A6J3RMN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the selenium-binding protein family.
messages: Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria. Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport.
messages: Interacts with USP33.
messages: Membrane
messages: Nucleus
messages: cytosol

9739:LOC101338380
gene id: 9739:LOC101338380
uniprot id: A0A6J3RJW2
uniprot id: A0A6J3RK58
uniprot id: A0A6J3RK87
uniprot id: A0A6J3RL18
uniprot id: A0A6J3RLW4
names: Similarity
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.

9739:EXOC6
gene id: 9739:EXOC6
uniprot id: A0A2U4BPR5
uniprot id: A0A2U4BPX0
uniprot id: A0A2U4BQ26
uniprot id: A0A6J3Q4T3
uniprot id: A0A6J3Q591
names: Function
names: Similarity
messages: Belongs to the SEC15 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

9739:CNOT7
gene id: 9739:CNOT7
uniprot id: A0A2U4A838
uniprot id: A0A6J3QRC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

9739:N6AMT1
gene id: 9739:N6AMT1
uniprot id: A0A2U3UYV1
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

9739:PDS5A
gene id: 9739:PDS5A
uniprot id: A0A2U4ASB7
uniprot id: A0A2U4ASB9
uniprot id: A0A2U4ASD0
uniprot id: A0A2U4ASU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDS5 family.
messages: Nucleus

9739:DEUP1
gene id: 9739:DEUP1
uniprot id: A0A6J3RSY1
names: Similarity
messages: Belongs to the CEP63 family.

9739:IL13
gene id: 9739:IL13
uniprot id: A0A2U3V5Y5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-4/IL-13 family.
messages: Interacts with IL13RA2.
messages: Secreted

9739:SMG6
gene id: 9739:SMG6
uniprot id: A0A6J3QNF3
uniprot id: A0A6J3QNL3
uniprot id: A0A6J3QPB0
uniprot id: A0A6J3QPN3
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini.
messages: Nucleus
messages: Plays a role in nonsense-mediated mRNA decay.
messages: The PINc domain confers endonuclease activity and is expected to bind the catalytic metal ion.
messages: cytosol
messages: nucleolus
messages: telomere

9739:ARRDC3
gene id: 9739:ARRDC3
uniprot id: A0A2U4AWT9
names: Similarity
messages: Belongs to the arrestin family.

9739:TNS3
gene id: 9739:TNS3
uniprot id: A0A6J3RVY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTEN phosphatase protein family.
messages: focal adhesion

9739:ACTB
gene id: 9739:ACTB
uniprot id: A0A6J3PXY9
names: Similarity
messages: Belongs to the actin family.

9739:HJV
gene id: 9739:HJV
uniprot id: A0A2U3V3M8
uniprot id: A0A2U4A1A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

9739:NXPH3
gene id: 9739:NXPH3
uniprot id: A0A6J3QMM5
uniprot id: A0A6J3QMS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

9739:RPF1
gene id: 9739:RPF1
uniprot id: A0A2U4A319
names: Subcellular Location Annotation
messages: nucleolus

9739:LOXHD1
gene id: 9739:LOXHD1
uniprot id: A0A6J3PUM5
uniprot id: A0A6J3PUQ9
uniprot id: A0A6J3PVF9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:NFE2
gene id: 9739:NFE2
uniprot id: A0A2U3UYQ4
names: Similarity
messages: Belongs to the bZIP family. CNC subfamily.

9739:CSRNP3
gene id: 9739:CSRNP3
uniprot id: A0A2U3V432
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

9739:TNNT3
gene id: 9739:TNNT3
uniprot id: A0A6J3RT20
names: Function
names: Similarity
messages: Belongs to the troponin T family.
messages: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

9739:MEF2D
gene id: 9739:MEF2D
uniprot id: A0A6J3RE50
names: Subcellular Location Annotation
messages: Nucleus

9739:DOCK4
gene id: 9739:DOCK4
uniprot id: A0A2U4AJ94
names: Similarity
messages: Belongs to the DOCK family.

9739:KIF3C
gene id: 9739:KIF3C
uniprot id: A0A6J3PXJ8
uniprot id: A0A6J3PXN3
uniprot id: A0A6J3PXN8
uniprot id: A0A6J3PXU6
uniprot id: A0A6J3PY52
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9739:GPR39
gene id: 9739:GPR39
uniprot id: A0A2U4B2P7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9739:KMT2B
gene id: 9739:KMT2B
uniprot id: A0A6J3QED1
uniprot id: A0A6J3QED3
uniprot id: A0A6J3QEW6
uniprot id: A0A6J3QFE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.
messages: Nucleus

9739:SYNDIG1
gene id: 9739:SYNDIG1
uniprot id: A0A2U4AQD2
names: Similarity
messages: Belongs to the CD225/Dispanin family.

9739:ITGB3
gene id: 9739:ITGB3
uniprot id: A0A2U3V2D3
uniprot id: A0A6J3QME1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Melanosome
messages: Membrane
messages: Recycling endosome
messages: focal adhesion
messages: invadopodium membrane
messages: lamellipodium
messages: ruffle membrane

9739:FAM120B
gene id: 9739:FAM120B
uniprot id: A0A2U4CP10
uniprot id: A0A2U4CP11
uniprot id: A0A2U4CPA7
uniprot id: A0A2U4CPB3
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

9739:NHP2
gene id: 9739:NHP2
uniprot id: A0A2U4BZ14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

9739:HSPG2
gene id: 9739:HSPG2
uniprot id: A0A6J3Q5C3
uniprot id: A0A6J3Q5F0
uniprot id: A0A6J3Q5L6
uniprot id: A0A6J3Q5N1
uniprot id: A0A6J3Q5P3
uniprot id: A0A6J3Q5Z9
uniprot id: A0A6J3Q637
uniprot id: A0A6J3Q651
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

9739:SYT2
gene id: 9739:SYT2
uniprot id: A0A6J3QAE9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: synaptic vesicle membrane

9739:STAMBPL1
gene id: 9739:STAMBPL1
uniprot id: A0A2U3V5L4
uniprot id: A0A2U4BSI0
uniprot id: A0A2U4BSR1
names: Similarity
messages: Belongs to the peptidase M67C family.

9739:ZDHHC16
gene id: 9739:ZDHHC16
uniprot id: A0A2U3V123
uniprot id: A0A2U3V140
uniprot id: A0A2U4BQ00
uniprot id: A0A2U4BQ09
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9739:LOC101329036
gene id: 9739:LOC101329036
uniprot id: A0A2U4BVG9
uniprot id: A0A6J3RT07
uniprot id: A0A6J3RT15
uniprot id: A0A6J3RT88
uniprot id: A0A6J3RTD7
uniprot id: A0A6J3RTK8
uniprot id: A0A6J3RTL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HIT family.
messages: Belongs to the glycosyltransferase 29 family.
messages: Cytoplasm
messages: Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway.
messages: Homodimer. Associates with components of the exosome multienzyme ribonuclease complex, such as EXOSC3 and EXOSC4. Interacts with NDOR1.
messages: Membrane
messages: Nucleus

9739:CLUH
gene id: 9739:CLUH
uniprot id: A0A6J3QNE0
uniprot id: A0A6J3QNU0
uniprot id: A0A6J3QP38
uniprot id: A0A6J3QPE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLU family.
messages: Cytoplasm
messages: Cytoplasmic granule
messages: mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear-encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis.

9739:CATSPERE
gene id: 9739:CATSPERE
uniprot id: A0A2U4A5C9
names: Similarity
messages: Belongs to the CATSPERD family.

9739:SEZ6L2
gene id: 9739:SEZ6L2
uniprot id: A0A6J3Q0J7
uniprot id: A0A6J3Q0L9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:LOC101328165
gene id: 9739:LOC101328165
uniprot id: A0A2U4BWG1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9739:DBNDD1
gene id: 9739:DBNDD1
uniprot id: A0A6J3QG13
names: Similarity
messages: Belongs to the dysbindin family.

9739:LOC101327784
gene id: 9739:LOC101327784
uniprot id: A0A2U3V275
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9739:TMEM45B
gene id: 9739:TMEM45B
uniprot id: A0A2U3UZV1
uniprot id: A0A2U4BWP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

9739:TSPAN17
gene id: 9739:TSPAN17
uniprot id: A0A6J3R4K0
uniprot id: A0A6J3R6B3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:BCKDHA
gene id: 9739:BCKDHA
uniprot id: A0A6J3QHU2
uniprot id: A0A6J3QIB9
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: Together with BCKDHB forms the heterotetrameric E1 subunit of the mitochondrial branched-chain alpha-ketoacid dehydrogenase (BCKD) complex. The BCKD complex catalyzes the multi-step oxidative decarboxylation of alpha-ketoacids derived from the branched-chain amino-acids valine, leucine and isoleucine producing CO2 and acyl-CoA which is subsequently utilized to produce energy. The E1 subunit catalyzes the first step with the decarboxylation of the alpha-ketoacid forming an enzyme-product intermediate. A reductive acylation mediated by the lipoylamide cofactor of E2 extracts the acyl group from the E1 active site for the next step of the reaction.

9739:XKRX
gene id: 9739:XKRX
uniprot id: A0A2U4B3L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

9739:PFDN4
gene id: 9739:PFDN4
uniprot id: A0A2U3V0I0
uniprot id: A0A2U4C297
uniprot id: A0A2U4C2B1
uniprot id: A0A2U4C2D2
uniprot id: A0A2U4C2I7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

9739:S1PR4
gene id: 9739:S1PR4
uniprot id: A0A2U4ALL1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9739:MRPS11
gene id: 9739:MRPS11
uniprot id: A0A2U3V7M3
uniprot id: A0A2U4C7E2
uniprot id: A0A2U4C7F6
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

9739:CEBPG
gene id: 9739:CEBPG
uniprot id: A0A2U4BTJ6
names: Similarity
messages: Belongs to the bZIP family. C/EBP subfamily.

9739:NKRF
gene id: 9739:NKRF
uniprot id: A0A2U3V4G5
names: Similarity
messages: Belongs to the CARF family.

9739:HNF1A
gene id: 9739:HNF1A
uniprot id: A0A6J3PSK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HNF1 homeobox family.
messages: Nucleus

9739:FOXE1
gene id: 9739:FOXE1
uniprot id: A0A2U4CGC3
names: Subcellular Location Annotation
messages: Nucleus

9739:LOC117313025
gene id: 9739:LOC117313025
uniprot id: A0A6J3RNF1
uniprot id: A0A6J3RP28
uniprot id: A0A6J3RPT6
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

9739:CLUAP1
gene id: 9739:CLUAP1
uniprot id: A0A2U4B8L0
uniprot id: A0A2U4BA51
uniprot id: A0A2U4BC30
uniprot id: A0A2U4BE06
uniprot id: A0A2U4BGA8
uniprot id: A0A2U4BIG7
uniprot id: A0A6J3PZ60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLUAP1 family.
messages: cilium

9739:IDO1
gene id: 9739:IDO1
uniprot id: A0A2U4A8W4
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

9739:PDE4D
gene id: 9739:PDE4D
uniprot id: A0A2U3V811
uniprot id: A0A2U4AX70
uniprot id: A0A2U4AX86
uniprot id: A0A2U4AXA7
uniprot id: A0A6J3R208
uniprot id: A0A6J3R2G9
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9739:SLC10A2
gene id: 9739:SLC10A2
uniprot id: A0A2U3V4B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

9739:YPEL4
gene id: 9739:YPEL4
uniprot id: A0A6J3RQI2
names: Similarity
messages: Belongs to the yippee family.

9739:SEC61G
gene id: 9739:SEC61G
uniprot id: A0A2U3V9E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecE/SEC61-gamma family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:MRPL1
gene id: 9739:MRPL1
uniprot id: A0A2U4B533
uniprot id: A0A2U4B584
uniprot id: A0A6J3RE65
uniprot id: A0A6J3REP2
uniprot id: A0A6J3RGF0
names: Subcellular Location Annotation
messages: Mitochondrion

9739:DTD2
gene id: 9739:DTD2
uniprot id: A0A2U4AFE8
uniprot id: A0A6J3QZ11
names: Similarity
messages: Belongs to the DTD family.

9739:CNKSR3
gene id: 9739:CNKSR3
uniprot id: A0A6J3S9V1
uniprot id: A0A6J3SAV9
names: Similarity
messages: Belongs to the CNKSR family.

9739:CCNE2
gene id: 9739:CCNE2
uniprot id: A0A2U4AIQ2
uniprot id: A0A6J3QAQ3
names: Similarity
messages: Belongs to the cyclin family.

9739:TNFSF15
gene id: 9739:TNFSF15
uniprot id: A0A2U4C9B7
uniprot id: A0A2U4C9B9
uniprot id: A0A2U4C9D6
names: Similarity
messages: Belongs to the tumor necrosis factor family.

9739:SLC15A5
gene id: 9739:SLC15A5
uniprot id: A0A2U4BHM3
names: Similarity
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.

9739:ARFGEF2
gene id: 9739:ARFGEF2
uniprot id: A0A2U4C1S7
uniprot id: A0A6J3Q3R0
uniprot id: A0A6J3Q3X6
names: Subcellular Location Annotation
messages: Golgi apparatus
messages: perinuclear region

9739:CDC34
gene id: 9739:CDC34
uniprot id: A0A2U4AJM4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9739:UBA6
gene id: 9739:UBA6
uniprot id: A0A2U4ARR8
uniprot id: A0A2U4ARS0
uniprot id: A0A2U4ARS5
uniprot id: A0A2U4ART0
uniprot id: A0A2U4AS85
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

9739:LOC117313964
gene id: 9739:LOC117313964
uniprot id: A0A6J3S3B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

9739:OCLN
gene id: 9739:OCLN
uniprot id: A0A2U4AWX8
uniprot id: A0A2U4AWY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
messages: Membrane
messages: tight junction

9739:SLC30A9
gene id: 9739:SLC30A9
uniprot id: A0A2U4AS68
uniprot id: A0A2U4AS69
uniprot id: A0A2U4ASP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Endoplasmic reticulum
messages: Membrane
messages: Mitochondrion membrane
messages: Nucleus

9739:CNPY1
gene id: 9739:CNPY1
uniprot id: A0A2U4AXT7
names: Similarity
messages: Belongs to the canopy family.

9739:TRIM36
gene id: 9739:TRIM36
uniprot id: A0A2U4BTH6
names: Subcellular Location Annotation
messages: cytoskeleton

9739:SLC10A3
gene id: 9739:SLC10A3
uniprot id: A0A2U4B7M7
uniprot id: A0A2U4B7U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

9739:IRX3
gene id: 9739:IRX3
uniprot id: A0A6J3QE43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

9739:CPT1C
gene id: 9739:CPT1C
uniprot id: A0A6J3QDM8
uniprot id: A0A6J3QDN3
uniprot id: A0A6J3QDN5
uniprot id: A0A6J3QE12
uniprot id: A0A6J3QE64
uniprot id: A0A6J3QEI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

9739:TLN2
gene id: 9739:TLN2
uniprot id: A0A6J3QZJ7
names: Subcellular Location Annotation
messages: cytoskeleton

9739:LOC101317031
gene id: 9739:LOC101317031
uniprot id: A0A2U3UZS1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

9739:EPO
gene id: 9739:EPO
uniprot id: A0A6J3Q048
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPO/TPO family.
messages: Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3.
messages: Secreted

9739:MAPK6
gene id: 9739:MAPK6
uniprot id: A0A2U4B5L0
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

9739:TNRC6C
gene id: 9739:TNRC6C
uniprot id: A0A2U4BMC0
uniprot id: A0A2U4BMC7
uniprot id: A0A6J3QPS9
uniprot id: A0A6J3QPT5
uniprot id: A0A6J3QPY5
uniprot id: A0A6J3QPZ0
uniprot id: A0A6J3QQH9
uniprot id: A0A6J3QQN0
uniprot id: A0A6J3QR03
names: Similarity
messages: Belongs to the GW182 family.

9739:TEAD2
gene id: 9739:TEAD2
uniprot id: A0A6J3QDH9
uniprot id: A0A6J3QDW3
uniprot id: A0A6J3QE15
uniprot id: A0A6J3QED6
names: Subcellular Location Annotation
messages: Nucleus

9739:LOC109547360
gene id: 9739:LOC109547360
uniprot id: A0A6J3RYS8
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

9739:LTF
gene id: 9739:LTF
uniprot id: A0A2U4CA96
uniprot id: A0A2U4CAA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transferrin family.
messages: Cytoplasmic granule
messages: Secreted
messages: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate.

9739:LOC109550896
gene id: 9739:LOC109550896
uniprot id: A0A6J3RL76
names: Similarity
messages: Belongs to the GroES chaperonin family.

9739:PIGG
gene id: 9739:PIGG
uniprot id: A0A2U4AQ01
uniprot id: A0A2U4AQD9
uniprot id: A0A6J3RBX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGG subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:CACNA2D4
gene id: 9739:CACNA2D4
uniprot id: A0A6J3S9V9
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

9739:TK2
gene id: 9739:TK2
uniprot id: A0A6J3QGB1
names: Similarity
messages: Belongs to the DCK/DGK family.

9739:EMSY
gene id: 9739:EMSY
uniprot id: A0A6J3RU15
uniprot id: A0A6J3RU19
uniprot id: A0A6J3RUA3
uniprot id: A0A6J3RUA7
uniprot id: A0A6J3RUF2
uniprot id: A0A6J3RUF7
uniprot id: A0A6J3RUH2
uniprot id: A0A6J3RUH5
uniprot id: A0A6J3RUS1
uniprot id: A0A6J3RUS5
names: Subcellular Location Annotation
messages: Nucleus

9739:ANKRD13A
gene id: 9739:ANKRD13A
uniprot id: A0A2U4CJZ6
uniprot id: A0A2U4CK00
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

9739:ANAPC2
gene id: 9739:ANAPC2
uniprot id: A0A6J3RLV0
names: Similarity
messages: Belongs to the cullin family.

9739:LAPTM4A
gene id: 9739:LAPTM4A
uniprot id: A0A6J3PUT1
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

9739:LOC101320747
gene id: 9739:LOC101320747
uniprot id: A0A2U3VAI0
names: Similarity
messages: Belongs to the GST superfamily. Mu family.

9739:LOC101321652
gene id: 9739:LOC101321652
uniprot id: A0A6J3RBX0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:TRAM1
gene id: 9739:TRAM1
uniprot id: A0A2U4AIF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

9739:GGA2
gene id: 9739:GGA2
uniprot id: A0A2U4A8S9
uniprot id: A0A2U4A8W1
uniprot id: A0A2U4A9H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

9739:ECSIT
gene id: 9739:ECSIT
uniprot id: A0A6J3R5Q3
uniprot id: A0A6J3R5S9
uniprot id: A0A6J3R6A8
uniprot id: A0A6J3R6N4
uniprot id: A0A6J3R6N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.
messages: Belongs to the ECSIT family.
messages: Cytoplasm
messages: Mitochondrion
messages: Nucleus

9739:LOC101329731
gene id: 9739:LOC101329731
uniprot id: A0A2U4CIL2
names: Similarity
messages: Belongs to the KHDC1 family.

9739:DIO3
gene id: 9739:DIO3
uniprot id: A0A6J3R117
names: Function
names: Similarity
messages: Belongs to the iodothyronine deiodinase family.
messages: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).

9739:MAP3K6
gene id: 9739:MAP3K6
uniprot id: A0A6J3Q0X5
uniprot id: A0A6J3Q0Y1
uniprot id: A0A6J3Q101
uniprot id: A0A6J3Q138
uniprot id: A0A6J3Q1H3
uniprot id: A0A6J3Q1I3
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

9739:CCDC85A
gene id: 9739:CCDC85A
uniprot id: A0A2U4BY10
uniprot id: A0A2U4BY57
uniprot id: A0A2U4BY59
uniprot id: A0A6J3PWP1
uniprot id: A0A6J3PWS6
uniprot id: A0A6J3PX58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC85 family.
messages: adherens junction

9739:RBP5
gene id: 9739:RBP5
uniprot id: A0A6J3S3Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm

9739:IL4R
gene id: 9739:IL4R
uniprot id: A0A6J3PY45
uniprot id: A0A6J3PY69
names: Function
names: Similarity
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.

9739:DEDD2
gene id: 9739:DEDD2
uniprot id: A0A6J3QE17
names: Subcellular Location Annotation
messages: nucleolus

9739:EMC3
gene id: 9739:EMC3
uniprot id: A0A2U3UZE3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC3 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

9739:LIG1
gene id: 9739:LIG1
uniprot id: A0A6J3QIQ6
uniprot id: A0A6J3QIR7
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.

9739:MTAP
gene id: 9739:MTAP
uniprot id: A0A2U4BBA0
uniprot id: A0A2U4BBK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Cytoplasm
messages: Homotrimer.
messages: Nucleus

9739:CUL4A
gene id: 9739:CUL4A
uniprot id: A0A2U4A6B3
uniprot id: A0A2U4A6F8
uniprot id: A0A6J3QBA4
names: Similarity
messages: Belongs to the cullin family.

9739:ART3
gene id: 9739:ART3
uniprot id: A0A6J3RHC4
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

9739:RPSA
gene id: 9739:RPSA
uniprot id: A0A2U3V9J5
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acylated. Acylation may be a prerequisite for conversion of the monomeric 37 kDa laminin receptor precursor (37LRP) to the mature dimeric 67 kDa laminin receptor (67LR), and may provide a mechanism for membrane association.
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Cell membrane
messages: Cleaved by stromelysin-3 (ST3) at the cell surface. Cleavage by stromelysin-3 may be a mechanism to alter cell-extracellular matrix interactions.
messages: Cytoplasm
messages: Monomer (37LRP) and homodimer (67LR). Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Interacts with RPS21. Interacts with several laminins including at least LAMB1. Interacts with MDK. The mature dimeric form interacts with PPP1R16B (via its fourth ankyrin repeat). Interacts with PPP1CA only in the presence of PPP1R16B.
messages: Nucleus
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. Acts as a PPP1R16B-dependent substrate of PPP1CA.
messages: This protein appears to have acquired a second function as a laminin receptor specifically in the vertebrate lineage.

9739:GLG1
gene id: 9739:GLG1
uniprot id: A0A6J3QHD7
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Golgi outpost
messages: Membrane
messages: microtubule organizing center

9739:SH3RF2
gene id: 9739:SH3RF2
uniprot id: A0A2U4AGT6
names: Similarity
messages: Belongs to the SH3RF family.

9739:EP300
gene id: 9739:EP300
uniprot id: A0A2U4C281
names: Subcellular Location Annotation
messages: Cytoplasm

9739:CLSTN3
gene id: 9739:CLSTN3
uniprot id: A0A6J3S967
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsyntenin family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Postsynaptic cell membrane

9739:XIRP1
gene id: 9739:XIRP1
uniprot id: A0A2U3V4L8
names: Domain
names: Function
names: Similarity
messages: Belongs to the Xin family.
messages: Protects actin filaments from depolymerization.
messages: Xin repeats bind F-actin.

9739:LOC101337990
gene id: 9739:LOC101337990
uniprot id: A0A6J3R1P1
names: Similarity
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.

9739:DPP7
gene id: 9739:DPP7
uniprot id: A0A6J3RKZ2
uniprot id: A0A6J3RLU2
names: Similarity
messages: Belongs to the peptidase S28 family.

9739:EBNA1BP2
gene id: 9739:EBNA1BP2
uniprot id: A0A6J3PRT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP2 family.
messages: Required for the processing of the 27S pre-rRNA.
messages: nucleolus

9739:MTMR7
gene id: 9739:MTMR7
uniprot id: A0A6J3QQZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

9739:ATG4C
gene id: 9739:ATG4C
uniprot id: A0A2U4A3E9
uniprot id: A0A6J3S3I7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

9739:ST3GAL2
gene id: 9739:ST3GAL2
uniprot id: A0A6J3QCS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9739:REM1
gene id: 9739:REM1
uniprot id: A0A6J3Q4I8
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

9739:COLGALT1
gene id: 9739:COLGALT1
uniprot id: A0A6J3R5S6
uniprot id: A0A6J3R7D4
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

9739:PCBD1
gene id: 9739:PCBD1
uniprot id: A0A6J3Q7J3
uniprot id: A0A6J3Q7Y0
uniprot id: A0A6J3Q8B6
uniprot id: A0A6J3Q8D4
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

9739:GPR132
gene id: 9739:GPR132
uniprot id: A0A2U4B819
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9739:PPP1R3B
gene id: 9739:PPP1R3B
uniprot id: A0A2U4A845
uniprot id: A0A2U4A846
uniprot id: A0A2U4A8U4
uniprot id: A0A6J3QQN1
names: Subunit
messages: Interacts with glycogen, PPP1CC catalytic subunit of PP1 and PYGL. Associates with glycogen particles. Forms complexes with debranching enzyme, glycogen phosphorylase, glycogen synthase and phosphorylase kinase which is necessary for its regulation of PP1 activity.

9739:SCARB2
gene id: 9739:SCARB2
uniprot id: A0A2U3V2Q4
names: Similarity
messages: Belongs to the CD36 family.

9739:SRRT
gene id: 9739:SRRT
uniprot id: A0A6J3PZE2
uniprot id: A0A6J3PZE7
uniprot id: A0A6J3PZJ3
uniprot id: A0A6J3PZM2
uniprot id: A0A6J3PZZ0
names: Similarity
messages: Belongs to the ARS2 family.

9739:PACSIN2
gene id: 9739:PACSIN2
uniprot id: A0A6J3S4C9
uniprot id: A0A6J3S4L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PACSIN family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Early endosome
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: caveola
messages: cytoskeleton
messages: ruffle membrane

9739:SPIN2B
gene id: 9739:SPIN2B
uniprot id: A0A6J3QSR9
names: Similarity
messages: Belongs to the SPIN/STSY family.

9739:LOC101319552
gene id: 9739:LOC101319552
uniprot id: A0A2U4AZC9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9739:CAPN10
gene id: 9739:CAPN10
uniprot id: A0A6J3RKK5
uniprot id: A0A6J3RKY9
uniprot id: A0A6J3RKZ3
uniprot id: A0A6J3RLT2
uniprot id: A0A6J3RMF2
names: Similarity
messages: Belongs to the peptidase C2 family.

9739:CDK1
gene id: 9739:CDK1
uniprot id: A0A2U4BDY1
uniprot id: A0A2U4BEB1
names: Similarity
messages: Belongs to the protein kinase superfamily.

9739:C15H20orf173
gene id: 9739:C15H20orf173
uniprot id: A0A6J3Q221
uniprot id: A0A6J3Q298
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9739:ALG2
gene id: 9739:ALG2
uniprot id: A0A2U3V7F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.
messages: Membrane

9739:LOC101316401
gene id: 9739:LOC101316401
uniprot id: A0A2U4ABJ9
names: Similarity
messages: Belongs to the SH3BGR family.

9739:DOCK11
gene id: 9739:DOCK11
uniprot id: A0A6J3QTR3
uniprot id: A0A6J3QU70
uniprot id: A0A6J3QUE5
uniprot id: A0A6J3QUN6
uniprot id: A0A6J3QVD8
names: Similarity
messages: Belongs to the DOCK family.

9739:THNSL1
gene id: 9739:THNSL1
uniprot id: A0A2U4B6Y7
uniprot id: A0A2U4B760
names: Similarity
messages: Belongs to the threonine synthase family.

9739:CLSPN
gene id: 9739:CLSPN
uniprot id: A0A2U4BKF1
uniprot id: A0A6J3PV53
uniprot id: A0A6J3PVG1
names: Subcellular Location Annotation
messages: Nucleus

9739:LOC117308962
gene id: 9739:LOC117308962
uniprot id: A0A6J3QCF2
names: Subcellular Location Annotation
messages: Nucleus

9739:PLD4
gene id: 9739:PLD4
uniprot id: A0A6J3QV91
names: Similarity
messages: Belongs to the phospholipase D family.

9739:TMSB4X
gene id: 9739:TMSB4X
uniprot id: A0A6J3QUH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

9739:RASSF5
gene id: 9739:RASSF5
uniprot id: A0A6J3R1E1
names: Subcellular Location Annotation
messages: cytoskeleton

9739:LOC117311132
gene id: 9739:LOC117311132
uniprot id: A0A2U3VA96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRIPT family.
messages: Cytoplasm

9739:ARPC2
gene id: 9739:ARPC2
uniprot id: A0A2U4BN31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC2 family.
messages: Cell projection
messages: Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC. Interacts with SHANK3; the interaction probably mediates the association of SHANK3 with the Arp2/3 complex.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton
messages: synaptosome

9739:PLB1
gene id: 9739:PLB1
uniprot id: A0A6J3PX90
uniprot id: A0A6J3PX99
uniprot id: A0A6J3PXE4
uniprot id: A0A6J3PXH4
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the 'GDSL' lipolytic enzyme family. Phospholipase B1 subfamily.
messages: Cell membrane
messages: Membrane

9739:ZDHHC19
gene id: 9739:ZDHHC19
uniprot id: A0A6J3R9W6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9739:TFDP2
gene id: 9739:TFDP2
uniprot id: A0A2U4B9D7
uniprot id: A0A2U4B9E4
uniprot id: A0A2U4B9E9
uniprot id: A0A2U4B9J1
uniprot id: A0A2U4B9J4
uniprot id: A0A2U4B9U2
uniprot id: A0A2U4B9U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

9739:RAD21
gene id: 9739:RAD21
uniprot id: A0A2U4B360
uniprot id: A0A2U4B3K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

9739:DUT
gene id: 9739:DUT
uniprot id: A0A2U3V881
uniprot id: A0A2U4AUP5
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Involved in nucleotide metabolism via production of dUMP, the immediate precursor of thymidine nucleotides, and decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

9739:P2RY1
gene id: 9739:P2RY1
uniprot id: A0A2U3V5F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9739:RNF121
gene id: 9739:RNF121
uniprot id: A0A2U3V037
uniprot id: A0A2U4BPS2
uniprot id: A0A6J3RUU6
names: Subcellular Location Annotation
messages: Membrane

9739:IL17F
gene id: 9739:IL17F
uniprot id: A0A2U4CJA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

9739:TM4SF4
gene id: 9739:TM4SF4
uniprot id: A0A2U4B8Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

9739:FOXD2
gene id: 9739:FOXD2
uniprot id: A0A2U4BJ79
names: Subcellular Location Annotation
messages: Nucleus

9739:KCNV2
gene id: 9739:KCNV2
uniprot id: A0A2U4BAU3
names: Subcellular Location Annotation
messages: Membrane

9739:NTRK2
gene id: 9739:NTRK2
uniprot id: A0A6J3RG72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

9739:NSUN7
gene id: 9739:NSUN7
uniprot id: A0A2U4ASA7
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:CHRM5
gene id: 9739:CHRM5
uniprot id: A0A2U4BBT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

9739:LOC101322802
gene id: 9739:LOC101322802
uniprot id: A0A2U4BNP8
uniprot id: A0A2U4BNZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

9739:BGN
gene id: 9739:BGN
uniprot id: A0A6J3QU24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: May be involved in collagen fiber assembly.
messages: extracellular matrix

9739:NUCB1
gene id: 9739:NUCB1
uniprot id: A0A6J3QDC3
names: Similarity
messages: Belongs to the nucleobindin family.

9739:CD3D
gene id: 9739:CD3D
uniprot id: A0A2U3V0Y4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9739:AQP9
gene id: 9739:AQP9
uniprot id: A0A2U4CB77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

9739:LOC109549564
gene id: 9739:LOC109549564
uniprot id: A0A6J3R1P7
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: nucleolus

9739:ATP7A
gene id: 9739:ATP7A
uniprot id: A0A2U4B3U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane
messages: trans-Golgi network membrane

9739:CAMSAP2
gene id: 9739:CAMSAP2
uniprot id: A0A6J3QLK4
uniprot id: A0A6J3QMB2
uniprot id: A0A6J3QMD2
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

9739:SMYD2
gene id: 9739:SMYD2
uniprot id: A0A2U3ZYU2
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically trimethylates histone H3 'Lys-4' (H3K4me3) in vivo. The activity requires interaction with HSP90alpha. Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'.
messages: cytosol

9739:PLXNA3
gene id: 9739:PLXNA3
uniprot id: A0A6J3QRH4
uniprot id: A0A6J3QRI0
uniprot id: A0A6J3QRV8
uniprot id: A0A6J3QRW3
uniprot id: A0A6J3QSB2
uniprot id: A0A6J3QSB5
uniprot id: A0A6J3QSC8
uniprot id: A0A6J3QSX2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:YIF1A
gene id: 9739:YIF1A
uniprot id: A0A6J3RQY9
uniprot id: A0A6J3RR67
uniprot id: A0A6J3RRN2
uniprot id: A0A6J3RRP0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIF1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Has a role in transport between endoplasmic reticulum and Golgi.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:MYH1
gene id: 9739:MYH1
uniprot id: A0A6J3QME4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: myofibril

9739:LOC117313797
gene id: 9739:LOC117313797
uniprot id: A0A6J3RYX8
names: Similarity
messages: Belongs to the syntaxin family.

9739:NSMCE2
gene id: 9739:NSMCE2
uniprot id: A0A2U4B2X2
uniprot id: A0A2U4B2X3
uniprot id: A0A2U4B2Z0
uniprot id: A0A2U4B3C3
uniprot id: A0A6J3Q8G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NSE2 family.
messages: Nucleus

9739:SLC35F1
gene id: 9739:SLC35F1
uniprot id: A0A6J3S9N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

9739:PIGP
gene id: 9739:PIGP
uniprot id: A0A2U3V3L2
uniprot id: A0A2U3V3Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGP family.
messages: Membrane
messages: Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

9739:LMF2
gene id: 9739:LMF2
uniprot id: A0A6J3S3V9
uniprot id: A0A6J3S416
uniprot id: A0A6J3S4X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase maturation factor family.
messages: Endoplasmic reticulum membrane
messages: Involved in the maturation of specific proteins in the endoplasmic reticulum.
messages: Membrane

9739:ADRB1
gene id: 9739:ADRB1
uniprot id: A0A2U4BQW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling (By similarity). Involved in the regulation of sleep/wake behaviors.
messages: Cell membrane
messages: Interacts (via C-terminus PDZ motif) with RAPGEF2; the interaction is direct. Interacts with GOPC, MAGI3 and DLG4.
messages: Membrane

9739:MEPCE
gene id: 9739:MEPCE
uniprot id: A0A6J3Q2N6
uniprot id: A0A6J3Q2P5
names: Similarity
messages: Belongs to the methyltransferase superfamily.

9739:PDE11A
gene id: 9739:PDE11A
uniprot id: A0A2U4ABN3
uniprot id: A0A2U4ACA2
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9739:PRR5
gene id: 9739:PRR5
uniprot id: A0A6J3S480
uniprot id: A0A6J3S4D7
uniprot id: A0A6J3S4I3
uniprot id: A0A6J3S5A9
uniprot id: A0A6J3S5L2
names: Similarity
messages: Belongs to the PROTOR family.

9739:LOC117308300
gene id: 9739:LOC117308300
uniprot id: A0A6J3Q3R7
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.

9739:DNAH3
gene id: 9739:DNAH3
uniprot id: A0A6J3PZD6
names: Similarity
messages: Belongs to the dynein heavy chain family.

9739:MSH2
gene id: 9739:MSH2
uniprot id: A0A2U4C009
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).
messages: Nucleus

9739:FAM149A
gene id: 9739:FAM149A
uniprot id: A0A2U4A800
uniprot id: A0A2U4A802
names: Similarity
messages: Belongs to the FAM149 family.

9739:LOC101334888
gene id: 9739:LOC101334888
uniprot id: A0A6J3S5B7
uniprot id: A0A6J3S5C3
names: Similarity
messages: Belongs to the apolipoprotein L family.

9739:CCNH
gene id: 9739:CCNH
uniprot id: A0A6J3R334
names: Function
names: Similarity
names: Subunit
messages: Associates primarily with CDK7 and MAT1 to form the CAK complex. CAK can further associate with the core-TFIIH to form the TFIIH basal transcription factor.
messages: Belongs to the cyclin family. Cyclin C subfamily.
messages: Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

9739:PAM
gene id: 9739:PAM
uniprot id: A0A2U4BSX9
uniprot id: A0A2U4BSY4
uniprot id: A0A2U4BT87
uniprot id: A0A6J3R2I7
uniprot id: A0A6J3R2M6
uniprot id: A0A6J3R2N0
uniprot id: A0A6J3R318
uniprot id: A0A6J3R3A9
uniprot id: A0A6J3R3B4
uniprot id: A0A6J3R4P0
uniprot id: A0A6J3R4P5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Binds 2 Cu(2+) ions per subunit.
messages: Binds one Zn(2+) ion per subunit.
messages: In the C-terminal section; belongs to the peptidyl-alpha-hydroxyglycine alpha-amidating lyase family.
messages: In the N-terminal section; belongs to the copper type II ascorbate-dependent monooxygenase family.
messages: Membrane
messages: secretory vesicle membrane

9739:A2ML1
gene id: 9739:A2ML1
uniprot id: A0A6J3S949
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

9739:MNS1
gene id: 9739:MNS1
uniprot id: A0A2U4CAE1
uniprot id: A0A2U4CAE4
uniprot id: A0A2U4CAF8
uniprot id: A0A2U4CAF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MNS1 family.
messages: Nucleus
messages: cilium axoneme
messages: flagellum axoneme

9739:SLC5A10
gene id: 9739:SLC5A10
uniprot id: A0A6J3QJ82
uniprot id: A0A6J3QJC1
uniprot id: A0A6J3QJV8
uniprot id: A0A6J3QJX9
uniprot id: A0A6J3QKD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

9739:MEIG1
gene id: 9739:MEIG1
uniprot id: A0A2U3V0Z4
names: Function
names: Similarity
messages: Belongs to the MEIG1 family.
messages: Essential for spermiogenesis.

9739:MGAT2
gene id: 9739:MGAT2
uniprot id: A0A2U3VAP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 16 (GT16) protein family.
messages: Golgi apparatus membrane
messages: Membrane

9739:PRDX2
gene id: 9739:PRDX2
uniprot id: A0A2U3V3P5
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

9739:U2AF2
gene id: 9739:U2AF2
uniprot id: A0A6J3QI21
uniprot id: A0A6J3QI46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Necessary for the splicing of pre-mRNA.
messages: Nucleus

9739:ATP1A1
gene id: 9739:ATP1A1
uniprot id: A0A2U3V496
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Membrane

9739:SLC6A13
gene id: 9739:SLC6A13
uniprot id: A0A6J3S845
uniprot id: A0A6J3S9F0
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A13 subfamily.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane

9739:MAPKAPK3
gene id: 9739:MAPKAPK3
uniprot id: A0A6J3S340
names: Similarity
messages: Belongs to the protein kinase superfamily.

9739:CHD5
gene id: 9739:CHD5
uniprot id: A0A6J3QCG7
uniprot id: A0A6J3QCK3
uniprot id: A0A6J3QCL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

9739:DENR
gene id: 9739:DENR
uniprot id: A0A2U4CKP5
names: Similarity
messages: Belongs to the DENR family.

9739:FSCN3
gene id: 9739:FSCN3
uniprot id: A0A2U4AGH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

9739:ME2
gene id: 9739:ME2
uniprot id: A0A2U4BHC6
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

9739:IDH3A
gene id: 9739:IDH3A
uniprot id: A0A2U4CKP9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

9739:RNH1
gene id: 9739:RNH1
uniprot id: A0A6J3RS23
uniprot id: A0A6J3RS79
uniprot id: A0A6J3RSK1
uniprot id: A0A6J3RSS6
uniprot id: A0A6J3RSW7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Forms high-affinity heterodimers with RNASE1, ANG and RNASE2.
messages: Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play a role in redox homeostasis.

9739:SLC35A1
gene id: 9739:SLC35A1
uniprot id: A0A2U3V538
uniprot id: A0A2U4AVG5
uniprot id: A0A2U4AVH6
uniprot id: A0A2U4AVY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9739:ZSCAN30
gene id: 9739:ZSCAN30
uniprot id: A0A2U3V9A2
names: Subcellular Location Annotation
messages: Nucleus

9739:GAST
gene id: 9739:GAST
uniprot id: A0A2U3VAB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gastrin/cholecystokinin family.
messages: Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine.
messages: Secreted

9739:SPRTN
gene id: 9739:SPRTN
uniprot id: A0A2U4BVA1
uniprot id: A0A2U4BVA4
uniprot id: A0A2U4BVA6
uniprot id: A0A2U4BVA9
uniprot id: A0A2U4BVB2
uniprot id: A0A2U4BVG0
uniprot id: A0A2U4BVG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Spartan family.
messages: Chromosome
messages: Nucleus

9739:SULT4A1
gene id: 9739:SULT4A1
uniprot id: A0A6J3S497
uniprot id: A0A6J3S4K3
uniprot id: A0A6J3S5D0
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9739:LOC101332225
gene id: 9739:LOC101332225
uniprot id: A0A6J3RF24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

9739:GPD2
gene id: 9739:GPD2
uniprot id: A0A2U4ABF2
uniprot id: A0A2U4ABJ1
names: Function
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta-cell glucose-sensing device.

9739:LOC101329176
gene id: 9739:LOC101329176
uniprot id: A0A2U3V775
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

9739:CTPS1
gene id: 9739:CTPS1
uniprot id: A0A2U4BK29
uniprot id: A0A2U4BK51
uniprot id: A0A2U4BK94
uniprot id: A0A2U4BKG3
uniprot id: A0A2U4BKG8
uniprot id: A0A6J3PSK4
uniprot id: A0A6J3PSK5
uniprot id: A0A6J3PT30
names: Caution
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:ELL2
gene id: 9739:ELL2
uniprot id: A0A6J3R2H1
uniprot id: A0A6J3R2L0
uniprot id: A0A6J3R2Z5
uniprot id: A0A6J3R391
uniprot id: A0A6J3R396
uniprot id: A0A6J3R4M2
uniprot id: A0A6J3R4M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

9739:PCBD2
gene id: 9739:PCBD2
uniprot id: A0A2U4AGB9
uniprot id: A0A2U4AGS6
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

9739:KCNK3
gene id: 9739:KCNK3
uniprot id: A0A6J3PXI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

9739:MED15
gene id: 9739:MED15
uniprot id: A0A6J3PSZ0
uniprot id: A0A6J3PT54
uniprot id: A0A6J3PTI4
uniprot id: A0A6J3PTI9
uniprot id: A0A6J3PTL5
uniprot id: A0A6J3PU33
uniprot id: A0A6J3PU37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 15 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

9739:LOC101320902
gene id: 9739:LOC101320902
uniprot id: A0A2U3VAE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9739:LSM4
gene id: 9739:LSM4
uniprot id: A0A6J3R7I8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

9739:PLPP2
gene id: 9739:PLPP2
uniprot id: A0A6J3R7W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

9739:SELENOF
gene id: 9739:SELENOF
uniprot id: A0A2U3V247
names: Similarity
messages: Belongs to the selenoprotein M/F family.

9739:CUL3
gene id: 9739:CUL3
uniprot id: A0A2U4ADQ3
uniprot id: A0A2U4ADW6
uniprot id: A0A2U4AE73
names: Similarity
messages: Belongs to the cullin family.

9739:SSR3
gene id: 9739:SSR3
uniprot id: A0A2U3V7E2
uniprot id: A0A2U4C8Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-gamma family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

9739:ATRNL1
gene id: 9739:ATRNL1
uniprot id: A0A6J3Q5S5
uniprot id: A0A6J3Q614
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:ZNF165
gene id: 9739:ZNF165
uniprot id: A0A2U3V306
uniprot id: A0A6J3RY93
names: Subcellular Location Annotation
messages: Nucleus

9739:TGS1
gene id: 9739:TGS1
uniprot id: A0A2U3V2K8
names: Similarity
messages: Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.

9739:SH3YL1
gene id: 9739:SH3YL1
uniprot id: A0A2U4C0B6
uniprot id: A0A2U4C0K1
names: Similarity
names: Subunit
messages: Belongs to the SH3YL1 family.
messages: Interacts with SH3D19.

9739:SLC1A3
gene id: 9739:SLC1A3
uniprot id: A0A2U4AXJ2
uniprot id: A0A2U4AXM9
uniprot id: A0A2U4AY08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

9739:TMED3
gene id: 9739:TMED3
uniprot id: A0A2U4C7U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

9739:VDAC3
gene id: 9739:VDAC3
uniprot id: A0A2U3UZ92
names: Similarity
messages: Belongs to the eukaryotic mitochondrial porin family.

9739:TLX3
gene id: 9739:TLX3
uniprot id: A0A6J3R8U8
names: Subcellular Location Annotation
messages: Nucleus

9739:LOC101321139
gene id: 9739:LOC101321139
uniprot id: A0A6J3Q6J3
names: Similarity
messages: Belongs to the cytochrome P450 family.

9739:GADL1
gene id: 9739:GADL1
uniprot id: A0A2U4C9U7
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

9739:LYVE1
gene id: 9739:LYVE1
uniprot id: A0A2U3V6T5
uniprot id: A0A2U4CF27
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:LOC101328153
gene id: 9739:LOC101328153
uniprot id: A0A2U3V0S0
names: Subcellular Location Annotation
messages: Nucleus

9739:PLXNB1
gene id: 9739:PLXNB1
uniprot id: A0A6J3S1I8
uniprot id: A0A6J3S1J2
uniprot id: A0A6J3S1L3
uniprot id: A0A6J3S1L9
uniprot id: A0A6J3S1N1
uniprot id: A0A6J3S1N6
uniprot id: A0A6J3S1P1
uniprot id: A0A6J3S281
uniprot id: A0A6J3S287
uniprot id: A0A6J3S292
uniprot id: A0A6J3S2M6
uniprot id: A0A6J3S2N1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:C15H16orf71
gene id: 9739:C15H16orf71
uniprot id: A0A2U4AUC1
names: Function
names: Subcellular Location Annotation
messages: Dynein axonemal particle
messages: In cyliated cells, dynein axonemal particle-specific protein required for deployment of ODA to the axoneme. Interacts with outer dynein arm (ODA) subunits.

9739:TSPAN33
gene id: 9739:TSPAN33
uniprot id: A0A2U4AFM9
uniprot id: A0A2U4AFU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9739:STC2
gene id: 9739:STC2
uniprot id: A0A6J3R432
uniprot id: A0A6J3R4H9
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.

9739:GALNT13
gene id: 9739:GALNT13
uniprot id: A0A2U4A9W0
uniprot id: A0A2U4A9W1
uniprot id: A0A2U4A9Y3
uniprot id: A0A2U4AA85
uniprot id: A0A6J3RMP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9739:PKD2L1
gene id: 9739:PKD2L1
uniprot id: A0A6J3Q7P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Membrane
messages: cilium membrane

9739:S100PBP
gene id: 9739:S100PBP
uniprot id: A0A2U4BKL2
uniprot id: A0A6J3PXH8
names: Subcellular Location Annotation
messages: Nucleus

9739:TLL1
gene id: 9739:TLL1
uniprot id: A0A6J3REX1
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:PLIN4
gene id: 9739:PLIN4
uniprot id: A0A6J3R7D5
names: Similarity
messages: Belongs to the perilipin family.

9739:LOC101332672
gene id: 9739:LOC101332672
uniprot id: A0A6J3S8F8
names: Similarity
messages: Belongs to the NAC-beta family.

9739:MPHOSPH10
gene id: 9739:MPHOSPH10
uniprot id: A0A2U4C7R0
uniprot id: A0A2U4C7R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPP10 family.
messages: Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.
messages: nucleolus

9739:TNFSF13
gene id: 9739:TNFSF13
uniprot id: A0A6J3QNN3
uniprot id: A0A6J3QNS7
uniprot id: A0A6J3QP78
uniprot id: A0A6J3QPH7
uniprot id: A0A6J3QPI3
uniprot id: A0A6J3QPV9
uniprot id: A0A6J3QPW4
names: Similarity
messages: Belongs to the tumor necrosis factor family.

9739:ANKRD34B
gene id: 9739:ANKRD34B
uniprot id: A0A2U4AWJ5
names: Similarity
messages: Belongs to the ANKRD34 family.

9739:MADD
gene id: 9739:MADD
uniprot id: A0A6J3RP64
uniprot id: A0A6J3RP69
uniprot id: A0A6J3RP71
uniprot id: A0A6J3RP76
uniprot id: A0A6J3RP79
uniprot id: A0A6J3RP86
uniprot id: A0A6J3RP91
uniprot id: A0A6J3RP94
uniprot id: A0A6J3RPH0
uniprot id: A0A6J3RPI3
uniprot id: A0A6J3RPI9
uniprot id: A0A6J3RPJ5
uniprot id: A0A6J3RPK1
uniprot id: A0A6J3RPK6
uniprot id: A0A6J3RPM7
uniprot id: A0A6J3RPN4
uniprot id: A0A6J3RPP0
uniprot id: A0A6J3RPP6
uniprot id: A0A6J3RPQ0
uniprot id: A0A6J3RPQ7
uniprot id: A0A6J3RPR4
uniprot id: A0A6J3RPR8
uniprot id: A0A6J3RQ83
uniprot id: A0A6J3RQ86
uniprot id: A0A6J3RQ90
uniprot id: A0A6J3RQ94
uniprot id: A0A6J3RQA2
uniprot id: A0A6J3RQA7
uniprot id: A0A6J3RQB0
uniprot id: A0A6J3RQB6
uniprot id: A0A6J3RQC5
uniprot id: A0A6J3RQD0
uniprot id: A0A6J3RQD4
uniprot id: A0A6J3RQD9
uniprot id: A0A6J3RQE4
uniprot id: A0A6J3RQE9
uniprot id: A0A6J3RQF4
uniprot id: A0A6J3RQG0
uniprot id: A0A6J3RQG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MADD family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

9739:CRHR1
gene id: 9739:CRHR1
uniprot id: A0A6J3QNB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to stress. Plays a role in the response to anxiogenic stimuli.
messages: Membrane

9739:LOC101329634
gene id: 9739:LOC101329634
uniprot id: A0A2U3V3D2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9739:LOC109550456
gene id: 9739:LOC109550456
uniprot id: A0A6J3PXF9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

9739:DDX59
gene id: 9739:DDX59
uniprot id: A0A2U4A549
uniprot id: A0A2U4A589
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX59 subfamily.

9739:TMOD3
gene id: 9739:TMOD3
uniprot id: A0A2U4B5K1
uniprot id: A0A2U4B5U8
names: Subcellular Location Annotation
messages: cytoskeleton

9739:LOC101339388
gene id: 9739:LOC101339388
uniprot id: A0A6J3QSV9
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

9739:ZFP36L1
gene id: 9739:ZFP36L1
uniprot id: A0A6J3QX33
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

9739:UBE2L6
gene id: 9739:UBE2L6
uniprot id: A0A2U3V1Q7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9739:WDR3
gene id: 9739:WDR3
uniprot id: A0A2U4A3G4
names: Subcellular Location Annotation
messages: nucleolus

9739:LOC101337692
gene id: 9739:LOC101337692
uniprot id: A0A2U4CJE3
names: Similarity
messages: Belongs to the cytochrome P450 family.

9739:LOC109548102
gene id: 9739:LOC109548102
uniprot id: A0A2U4AG15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Early endosome
messages: Endosome
messages: Involved in trafficking and recycling of synaptic vesicles.
messages: Late endosome
messages: Membrane
messages: Recycling endosome
messages: autophagosome
messages: synaptic vesicle
messages: trans-Golgi network

9739:DDX5
gene id: 9739:DDX5
uniprot id: A0A6J3QNG9
uniprot id: A0A6J3QNW1
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.

9739:FGF13
gene id: 9739:FGF13
uniprot id: A0A2U4A1V4
uniprot id: A0A6J3QSU8
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9739:RIOK1
gene id: 9739:RIOK1
uniprot id: A0A2U4C573
uniprot id: A0A2U4C5D1
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

9739:DUXB
gene id: 9739:DUXB
uniprot id: A0A6J3QFN1
names: Subcellular Location Annotation
messages: Nucleus

9739:TUB
gene id: 9739:TUB
uniprot id: A0A6J3RV27
uniprot id: A0A6J3RV33
uniprot id: A0A6J3RVJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUB family.
messages: Secreted

9739:SCARA5
gene id: 9739:SCARA5
uniprot id: A0A2U3V2V8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCARA5 family.
messages: Cell membrane
messages: Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1).
messages: Homotrimer.
messages: Membrane

9739:FGA
gene id: 9739:FGA
uniprot id: A0A2U3V9T1
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

9739:VKORC1L1
gene id: 9739:VKORC1L1
uniprot id: A0A2U4A907
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:PUF60
gene id: 9739:PUF60
uniprot id: A0A6J3Q8E0
uniprot id: A0A6J3Q8E1
uniprot id: A0A6J3Q8T8
uniprot id: A0A6J3Q958
uniprot id: A0A6J3Q960
uniprot id: A0A6J3Q965
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM half pint family.
messages: Nucleus

9739:CLUL1
gene id: 9739:CLUL1
uniprot id: A0A2U3V4T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clusterin family.
messages: Secreted

9739:DERL3
gene id: 9739:DERL3
uniprot id: A0A6J3PSS8
uniprot id: A0A6J3PSZ1
uniprot id: A0A6J3PTB9
uniprot id: A0A6J3PTD3
uniprot id: A0A6J3PTD8
uniprot id: A0A6J3PTW6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:MFAP5
gene id: 9739:MFAP5
uniprot id: A0A6J3S7N4
uniprot id: A0A6J3S7Y1
uniprot id: A0A6J3S956
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MFAP family.
messages: extracellular matrix

9739:GORASP1
gene id: 9739:GORASP1
uniprot id: A0A2U3V491
uniprot id: A0A6J3S113
uniprot id: A0A6J3S137
uniprot id: A0A6J3S1Q6
uniprot id: A0A6J3S266
names: Similarity
messages: Belongs to the GORASP family.

9739:MAEL
gene id: 9739:MAEL
uniprot id: A0A2U4BCV2
uniprot id: A0A2U4BCW1
uniprot id: A0A2U4BCY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the maelstrom family.
messages: Nucleus
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for the localization of germ-cell factors to the meiotic nuage.

9739:ADPRH
gene id: 9739:ADPRH
uniprot id: A0A2U4AAN4
uniprot id: A0A2U4AAU5
uniprot id: A0A2U4AB09
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

9739:DYRK2
gene id: 9739:DYRK2
uniprot id: A0A2U3V819
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

9739:SLC25A31
gene id: 9739:SLC25A31
uniprot id: A0A2U3V4A0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

9739:CRB2
gene id: 9739:CRB2
uniprot id: A0A6J3RJ74
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:WDR76
gene id: 9739:WDR76
uniprot id: A0A2U4BD26
uniprot id: A0A6J3R069
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: Interacts with CUL4A and/or CUL4B.
messages: Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

9739:CD3G
gene id: 9739:CD3G
uniprot id: A0A2U4BWQ3
uniprot id: A0A6J3RTV3
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Membrane
messages: The TCR-CD3 complex is composed of a CD3D/CD3E and a CD3G/CD3E heterodimers that preferentially associate with TCRalpha and TCRbeta, respectively, to form TCRalpha/CD3E/CD3G and TCRbeta/CD3G/CD3E trimers. In turn, the hexamer interacts with CD3Z homodimer to form the TCR-CD3 complex. Alternatively, TCRalpha and TCRbeta can be replaced by TCRgamma and TCRdelta.

9739:LOC101323099
gene id: 9739:LOC101323099
uniprot id: A0A2U4B8T4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9739:LOC101321922
gene id: 9739:LOC101321922
uniprot id: A0A6J3S696
uniprot id: A0A6J3S6S9
uniprot id: A0A6J3S7N2
names: Similarity
messages: Belongs to the intermediate filament family.

9739:ACTR3B
gene id: 9739:ACTR3B
uniprot id: A0A2U4AXY7
uniprot id: A0A2U4AXZ7
uniprot id: A0A2U4AY01
uniprot id: A0A2U4AY02
uniprot id: A0A2U4AY06
uniprot id: A0A2U4AY09
uniprot id: A0A2U4AY16
uniprot id: A0A2U4AY18
uniprot id: A0A2U4AY33
uniprot id: A0A2U4AY38
uniprot id: A0A2U4AYF3
uniprot id: A0A2U4AYF7
uniprot id: A0A6J3RY25
uniprot id: A0A6J3RYS6
names: Similarity
messages: Belongs to the actin family.

9739:POU3F2
gene id: 9739:POU3F2
uniprot id: A0A6J3S9T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

9739:SLC25A5
gene id: 9739:SLC25A5
uniprot id: A0A2U3V9E9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

9739:LOC101321341
gene id: 9739:LOC101321341
uniprot id: A0A6J3S7E6
uniprot id: A0A6J3S806
names: Similarity
messages: Belongs to the cytochrome P450 family.

9739:LCN8
gene id: 9739:LCN8
uniprot id: A0A6J3RKN8
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

9739:RPRD1B
gene id: 9739:RPRD1B
uniprot id: A0A2U4C1J1
uniprot id: A0A2U4C1J7
uniprot id: A0A2U4C1K7
uniprot id: A0A2U4C1M8
uniprot id: A0A2U4C1P6
names: Function
names: Similarity
names: Subunit
messages: Associates with the RNA polymerase II complex.
messages: Belongs to the UPF0400 (RTT103) family.
messages: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD.

9739:CNNM4
gene id: 9739:CNNM4
uniprot id: A0A2U3V0V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Cell membrane
messages: Membrane
messages: Metal transporter.

9739:GJC1
gene id: 9739:GJC1
uniprot id: A0A6J3QLI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins. Interacts with CNST.
messages: Belongs to the connexin family. Gamma-type subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9739:HSD17B6
gene id: 9739:HSD17B6
uniprot id: A0A2U3ZZV7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9739:STX6
gene id: 9739:STX6
uniprot id: A0A2U4CRS8
uniprot id: A0A2U4CS51
uniprot id: A0A6J3R5H5
uniprot id: A0A6J3R7C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Golgi apparatus membrane

9739:POMC
gene id: 9739:POMC
uniprot id: A0A2U3V8Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Anorexigenic peptide. Increases the pigmentation of skin by increasing melanin production in melanocytes.
messages: Belongs to the POMC family.
messages: Endogenous opiate.
messages: Endogenous orexigenic opiate.
messages: Secreted
messages: Stimulates the adrenal glands to release cortisol.

9739:LOC109547309
gene id: 9739:LOC109547309
uniprot id: A0A6J3RGJ6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9739:LOC117312997
gene id: 9739:LOC117312997
uniprot id: A0A6J3RPP3
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9739:LOC101335421
gene id: 9739:LOC101335421
uniprot id: A0A2U4AFK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

9739:LOC101339941
gene id: 9739:LOC101339941
uniprot id: A0A6J3RNK8
names: Similarity
messages: Belongs to the PDCD5 family.

9739:PITPNM2
gene id: 9739:PITPNM2
uniprot id: A0A6J3PR58
uniprot id: A0A6J3PRB3
uniprot id: A0A6J3PRQ1
uniprot id: A0A6J3PRT6
uniprot id: A0A6J3PS76
names: Similarity
messages: Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.

9739:ARX
gene id: 9739:ARX
uniprot id: A0A2U4AQS1
names: Subcellular Location Annotation
messages: Nucleus

9739:ZFPL1
gene id: 9739:ZFPL1
uniprot id: A0A2U4CAW9
uniprot id: A0A2U4CAX5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZFPL1 family.
messages: Interacts with GOLGA2/GM130.
messages: Membrane
messages: Required for cis-Golgi integrity and efficient ER to Golgi transport.
messages: The B box-type and RING-type zinc fingers although degenerate play a central role in function of the protein.
messages: cis-Golgi network membrane

9739:XKR4
gene id: 9739:XKR4
uniprot id: A0A2U4AIT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

9739:DLG1
gene id: 9739:DLG1
uniprot id: A0A2U4AA75
uniprot id: A0A2U4AAA7
uniprot id: A0A2U4AAK2
uniprot id: A0A2U4AAK5
uniprot id: A0A6J3R9T6
uniprot id: A0A6J3RAA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: Membrane

9739:LOC101321757
gene id: 9739:LOC101321757
uniprot id: A0A6J3PWK7
names: Similarity
messages: Belongs to the TMEM14 family.

9739:NAF1
gene id: 9739:NAF1
uniprot id: A0A6J3RFC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAF1 family.
messages: Nucleus

9739:SUSD2
gene id: 9739:SUSD2
uniprot id: A0A6J3PTB3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:DCLRE1B
gene id: 9739:DCLRE1B
uniprot id: A0A2U4A4B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

9739:BUD13
gene id: 9739:BUD13
uniprot id: A0A2U4BW30
uniprot id: A0A2U4BW31
names: Similarity
messages: Belongs to the CWC26 family.

9739:KCNJ13
gene id: 9739:KCNJ13
uniprot id: A0A2U3V904
uniprot id: A0A2U4ADU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

9739:LOC101336507
gene id: 9739:LOC101336507
uniprot id: A0A6J3R335
uniprot id: A0A6J3R340
uniprot id: A0A6J3R344
uniprot id: A0A6J3R350
uniprot id: A0A6J3R354
uniprot id: A0A6J3R358
uniprot id: A0A6J3R395
uniprot id: A0A6J3R3A0
uniprot id: A0A6J3R3B1
uniprot id: A0A6J3R3B7
uniprot id: A0A6J3R3C2
uniprot id: A0A6J3R3Q1
uniprot id: A0A6J3R3Q6
uniprot id: A0A6J3R3R2
uniprot id: A0A6J3R3R7
uniprot id: A0A6J3R3S3
uniprot id: A0A6J3R400
uniprot id: A0A6J3R404
uniprot id: A0A6J3R408
uniprot id: A0A6J3R413
uniprot id: A0A6J3R417
uniprot id: A0A6J3R5F3
uniprot id: A0A6J3R5F8
uniprot id: A0A6J3R5G4
uniprot id: A0A6J3R5G8
uniprot id: A0A6J3R5H4
uniprot id: A0A6J3R5I0
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

9739:LHPP
gene id: 9739:LHPP
uniprot id: A0A6J3Q7G5
uniprot id: A0A6J3Q7V4
uniprot id: A0A6J3Q8A8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

9739:LOC117311663
gene id: 9739:LOC117311663
uniprot id: A0A6J3R4I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.
messages: Cell projection
messages: Mitochondrion membrane

9739:F7
gene id: 9739:F7
uniprot id: A0A2U4A6A1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9739:LOC109550591
gene id: 9739:LOC109550591
uniprot id: A0A6J3QN31
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

9739:FRAT2
gene id: 9739:FRAT2
uniprot id: A0A2U4BPR2
names: Similarity
messages: Belongs to the GSK-3-binding protein family.

9739:RAB14
gene id: 9739:RAB14
uniprot id: A0A2U3V0K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Recycling endosome
messages: phagosome
messages: trans-Golgi network membrane

9739:CEMIP2
gene id: 9739:CEMIP2
uniprot id: A0A2U4BAK0
uniprot id: A0A6J3RHG8
uniprot id: A0A6J3RJ54
names: Similarity
messages: Belongs to the CEMIP family.

9739:IFT20
gene id: 9739:IFT20
uniprot id: A0A6J3QNQ8
names: Subcellular Location Annotation
messages: centriole
messages: cilium
messages: cis-Golgi network

9739:ABCC1
gene id: 9739:ABCC1
uniprot id: A0A6J3Q3R9
uniprot id: A0A6J3Q3Z2
uniprot id: A0A6J3Q4G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

9739:LOC117312107
gene id: 9739:LOC117312107
uniprot id: A0A6J3R943
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum

9739:LOC101319611
gene id: 9739:LOC101319611
uniprot id: A0A2U4B8T9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9739:PEX14
gene id: 9739:PEX14
uniprot id: A0A6J3QA83
uniprot id: A0A6J3QA87
uniprot id: A0A6J3QB66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-14 family.
messages: Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor. The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm. Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix.
messages: Peroxisome membrane

9739:TUFM
gene id: 9739:TUFM
uniprot id: A0A2U3V1T3
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

9739:TET2
gene id: 9739:TET2
uniprot id: A0A6J3RDY0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TET family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Chromosome
messages: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development.
messages: The zinc ions have a structural role.

9739:SLC34A3
gene id: 9739:SLC34A3
uniprot id: A0A6J3RJV2
uniprot id: A0A6J3RK81
uniprot id: A0A6J3RL13
uniprot id: A0A6J3RLV8
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Membrane

9739:LOC101332453
gene id: 9739:LOC101332453
uniprot id: A0A6J3QGN0
uniprot id: A0A6J3QGP7
uniprot id: A0A6J3QGQ4
uniprot id: A0A6J3QH92
uniprot id: A0A6J3QHC4
uniprot id: A0A6J3QHT6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Belongs to the TPPP family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9739:SLC1A7
gene id: 9739:SLC1A7
uniprot id: A0A2U4BJD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

9739:LOC117313972
gene id: 9739:LOC117313972
uniprot id: A0A6J3S303
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.

9739:LOC109551331
gene id: 9739:LOC109551331
uniprot id: A0A6J3S4K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RutC family.
messages: Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase.
messages: Peroxisome

9739:URAD
gene id: 9739:URAD
uniprot id: A0A2U4BGN1
names: Function
names: Similarity
messages: Belongs to the OHCU decarboxylase family.
messages: Catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin.

9739:CACNA1I
gene id: 9739:CACNA1I
uniprot id: A0A6J3S3J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite negative potentials, and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes.

9739:STMN4
gene id: 9739:STMN4
uniprot id: A0A6J3RK34
uniprot id: A0A6J3RKC8
uniprot id: A0A6J3RM11
names: Similarity
messages: Belongs to the stathmin family.

9739:LOC101328408
gene id: 9739:LOC101328408
uniprot id: A0A2U4C896
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9739:SNAP91
gene id: 9739:SNAP91
uniprot id: A0A2U4AUV4
uniprot id: A0A2U4AUV6
uniprot id: A0A6J3S8M8
uniprot id: A0A6J3S8N3
uniprot id: A0A6J3S8W8
uniprot id: A0A6J3S8X9
uniprot id: A0A6J3S8Y4
uniprot id: A0A6J3S986
uniprot id: A0A6J3S991
uniprot id: A0A6J3S9A9
uniprot id: A0A6J3SA72
uniprot id: A0A6J3SA76
uniprot id: A0A6J3SA81
uniprot id: A0A6J3SA84
uniprot id: A0A6J3SA89
uniprot id: A0A6J3SA93
uniprot id: A0A6J3SA95
uniprot id: A0A6J3SA97
uniprot id: A0A6J3SAA1
uniprot id: A0A6J3SAA2
uniprot id: A0A6J3SAB1
names: Similarity
messages: Belongs to the PICALM/SNAP91 family.

9739:TMEM178A
gene id: 9739:TMEM178A
uniprot id: A0A2U4BYP6
uniprot id: A0A2U4BYT4
names: Similarity
messages: Belongs to the TMEM178 family.

9739:CCDC172
gene id: 9739:CCDC172
uniprot id: A0A2U3V7A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC172 family.
messages: Cytoplasm

9739:TXLNG
gene id: 9739:TXLNG
uniprot id: A0A2U4AJV3
names: Similarity
messages: Belongs to the taxilin family.

9739:LOC117313332
gene id: 9739:LOC117313332
uniprot id: A0A6J3RSY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

9739:AMER2
gene id: 9739:AMER2
uniprot id: A0A2U4BGV3
names: Similarity
messages: Belongs to the Amer family.

9739:NUCB2
gene id: 9739:NUCB2
uniprot id: A0A2U4CF17
uniprot id: A0A2U4CF18
names: Similarity
messages: Belongs to the nucleobindin family.

9739:FASN
gene id: 9739:FASN
uniprot id: A0A6J3QIZ9
names: Function
messages: Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ([ACP]) domain.

9739:DMBX1
gene id: 9739:DMBX1
uniprot id: A0A6J3R3X4
uniprot id: A0A6J3R4T3
names: Subcellular Location Annotation
messages: Nucleus

9739:CNOT6L
gene id: 9739:CNOT6L
uniprot id: A0A2U4B525
uniprot id: A0A2U4B544
uniprot id: A0A2U4B5G6
uniprot id: A0A6J3RE39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

9739:GNG7
gene id: 9739:GNG7
uniprot id: A0A6J3R7I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

9739:TMEM37
gene id: 9739:TMEM37
uniprot id: A0A2U4B3U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Membrane
messages: tight junction

9739:VPS29
gene id: 9739:VPS29
uniprot id: A0A2U3UYR0
uniprot id: A0A2U3UZ49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
messages: Belongs to the VPS29 family.
messages: Endosome membrane

9739:LOC101339922
gene id: 9739:LOC101339922
uniprot id: A0A6J3RFK2
names: Similarity
messages: Belongs to the PHF5 family.

9739:TAF2
gene id: 9739:TAF2
uniprot id: A0A2U4B333
uniprot id: A0A2U4B335
uniprot id: A0A2U4B338
uniprot id: A0A2U4B353
uniprot id: A0A2U4B3I4
uniprot id: A0A2U4B3I9
uniprot id: A0A6J3Q8V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF2 family.
messages: Nucleus

9739:CHAC1
gene id: 9739:CHAC1
uniprot id: A0A2U3V3D8
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

9739:SLC25A29
gene id: 9739:SLC25A29
uniprot id: A0A2U4CR77
uniprot id: A0A2U4CRJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9739:FAM20A
gene id: 9739:FAM20A
uniprot id: A0A6J3QL86
uniprot id: A0A6J3QL92
uniprot id: A0A6J3QLD3
uniprot id: A0A6J3QLW7
uniprot id: A0A6J3QLY3
uniprot id: A0A6J3QME6
names: Similarity
messages: Belongs to the FAM20 family.

9739:ASIP
gene id: 9739:ASIP
uniprot id: A0A2U3V3V0
uniprot id: A0A2U4CLA8
names: Subcellular Location Annotation
messages: Secreted

9739:LOC109552010
gene id: 9739:LOC109552010
uniprot id: A0A6J3S0W7
uniprot id: A0A6J3S106
uniprot id: A0A6J3S1G8
uniprot id: A0A6J3S1Y6
names: Subcellular Location Annotation
messages: Nucleus

9739:DUSP12
gene id: 9739:DUSP12
uniprot id: A0A2U3V9Z1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

9739:TNFRSF1A
gene id: 9739:TNFRSF1A
uniprot id: A0A6J3S9D8
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:FAM126B
gene id: 9739:FAM126B
uniprot id: A0A2U4BNC8
uniprot id: A0A2U4BND0
uniprot id: A0A2U4BNI9
uniprot id: A0A2U4BNQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Hyccin family.
messages: Cell membrane
messages: Membrane
messages: cytosol

9739:LOC101332916
gene id: 9739:LOC101332916
uniprot id: A0A2U3V5H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 6A family.
messages: Membrane
messages: Mitochondrion inner membrane

9739:ELP4
gene id: 9739:ELP4
uniprot id: A0A2U4CDQ0
uniprot id: A0A6J3RVK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP4 family.
messages: Cytoplasm
messages: Nucleus

9739:RPS28
gene id: 9739:RPS28
uniprot id: A0A6J3R7A7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

9739:STXBP5L
gene id: 9739:STXBP5L
uniprot id: A0A2U4ACC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat L(2)GL family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

9739:LOC117313139
gene id: 9739:LOC117313139
uniprot id: A0A6J3S922
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

9739:IFI35
gene id: 9739:IFI35
uniprot id: A0A2U3UZY4
uniprot id: A0A2U4BPC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NMI family.
messages: Cytoplasm
messages: Nucleus
messages: Secreted

9739:PRC1
gene id: 9739:PRC1
uniprot id: A0A2U4C748
uniprot id: A0A2U4C760
uniprot id: A0A6J3R0J8
uniprot id: A0A6J3R0N8
uniprot id: A0A6J3R1W5
names: Similarity
messages: Belongs to the MAP65/ASE1 family.

9739:CCR10
gene id: 9739:CCR10
uniprot id: A0A6J3QPV4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9739:PAQR4
gene id: 9739:PAQR4
uniprot id: A0A6J3PYL1
uniprot id: A0A6J3PYU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

9739:PLK4
gene id: 9739:PLK4
uniprot id: A0A2U3V7K8
uniprot id: A0A2U3V7L8
uniprot id: A0A2U4AR77
uniprot id: A0A2U4AR78
uniprot id: A0A2U4AR79
names: Subcellular Location Annotation
messages: Cleavage furrow
messages: centriole

9739:LOC101337953
gene id: 9739:LOC101337953
uniprot id: A0A2U4BMY8
names: Similarity
names: Subunit
messages: Belongs to the NDUFAF4 family.
messages: Binds calmodulin. Interacts with NDUFAF3.

9739:RHBDD3
gene id: 9739:RHBDD3
uniprot id: A0A2U4CKD2
names: Subcellular Location Annotation
messages: Membrane

9739:RTN4
gene id: 9739:RTN4
uniprot id: A0A2U3V3S7
uniprot id: A0A2U3V3S9
uniprot id: A0A2U4BYH7
uniprot id: A0A2U4BYI9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:PARP11
gene id: 9739:PARP11
uniprot id: A0A2U3V0M0
names: Similarity
messages: Belongs to the ARTD/PARP family.

9739:LOC101335510
gene id: 9739:LOC101335510
uniprot id: A0A6J3PXD5
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.

9739:ERCC3
gene id: 9739:ERCC3
uniprot id: A0A2U4B2H4
uniprot id: A0A2U4B2X8
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

9739:KANSL2
gene id: 9739:KANSL2
uniprot id: A0A2U4BA41
uniprot id: A0A2U4BA75
uniprot id: A0A2U4BAH5
uniprot id: A0A6J3S7B3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.
messages: Component of the NSL complex at least composed of MOF/KAT8, KANSL1, KANSL2, KANSL3, MCRS1, PHF20, OGT1/OGT, WDR5 and HCFC1.
messages: Nucleus

9739:TM9SF4
gene id: 9739:TM9SF4
uniprot id: A0A6J3PY27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

9739:LOC101338348
gene id: 9739:LOC101338348
uniprot id: A0A2U3VA76
names: Similarity
messages: Belongs to the BEX family.

9739:ADAM32
gene id: 9739:ADAM32
uniprot id: A0A2U4A7T2
uniprot id: A0A2U4A7X5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:PHOSPHO2
gene id: 9739:PHOSPHO2
uniprot id: A0A2U4ACA4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.

9739:GSN
gene id: 9739:GSN
uniprot id: A0A6J3RI21
uniprot id: A0A6J3RI97
uniprot id: A0A6J3RIY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the villin/gelsolin family.
messages: Binds to actin and to fibronectin. Identified in a complex composed of ACTA1, COBL, GSN and TMSB4X. Interacts with the inactive form of EIF2AK2/PKR.
messages: Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis.
messages: cytoskeleton

9739:FLI1
gene id: 9739:FLI1
uniprot id: A0A2U4BVG8
uniprot id: A0A2U4BVN0
uniprot id: A0A6J3RT79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9739:RTRAF
gene id: 9739:RTRAF
uniprot id: A0A2U3V1C2
names: Similarity
messages: Belongs to the RTRAF family.

9739:MAP1LC3B
gene id: 9739:MAP1LC3B
uniprot id: A0A2U4BBE4
names: Similarity
messages: Belongs to the ATG8 family.

9739:DIS3
gene id: 9739:DIS3
uniprot id: A0A2U3V794
uniprot id: A0A2U4A6I8
uniprot id: A0A2U4A6N6
names: Similarity
messages: Belongs to the RNR ribonuclease family.

9739:FLAD1
gene id: 9739:FLAD1
uniprot id: A0A6J3RGS3
uniprot id: A0A6J3RGT3
uniprot id: A0A6J3RH33
uniprot id: A0A6J3RH37
names: Function
names: Similarity
messages: Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme.
messages: In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily.
messages: In the N-terminal section; belongs to the MoaB/Mog family.

9739:IMPA1
gene id: 9739:IMPA1
uniprot id: A0A2U3V1K7
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

9739:LOC101336613
gene id: 9739:LOC101336613
uniprot id: A0A2U4CD47
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9739:SLC35A4
gene id: 9739:SLC35A4
uniprot id: A0A2U3V5K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9739:RPL4
gene id: 9739:RPL4
uniprot id: A0A2U4CFJ5
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

9739:OPTC
gene id: 9739:OPTC
uniprot id: A0A2U4A0T2
names: Similarity
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.

9739:PALM
gene id: 9739:PALM
uniprot id: A0A6J3R7T1
uniprot id: A0A6J3R8E0
uniprot id: A0A6J3RAP9
names: Similarity
messages: Belongs to the paralemmin family.

9739:ACMSD
gene id: 9739:ACMSD
uniprot id: A0A6J3RP29
uniprot id: A0A6J3RPC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. ACMSD family.
messages: Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway.
messages: Monomer.

9739:ITPR2
gene id: 9739:ITPR2
uniprot id: A0A2U4BF85
uniprot id: A0A6J3S759
uniprot id: A0A6J3S7G8
uniprot id: A0A6J3S7Q9
uniprot id: A0A6J3S8Y5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the InsP3 receptor family.
messages: Endoplasmic reticulum membrane
messages: Homotetramer.
messages: Membrane
messages: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
messages: The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.

9739:RAD23A
gene id: 9739:RAD23A
uniprot id: A0A6J3R5G1
uniprot id: A0A6J3R5J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

9739:LOC117311914
gene id: 9739:LOC117311914
uniprot id: A0A6J3RB22
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

9739:TAFA2
gene id: 9739:TAFA2
uniprot id: A0A2U4CQE9
names: Similarity
messages: Belongs to the TAFA family.

9739:GPR37
gene id: 9739:GPR37
uniprot id: A0A2U3V6R9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9739:LOC117313795
gene id: 9739:LOC117313795
uniprot id: A0A6J3RYX4
uniprot id: A0A6J3RZX7
names: Similarity
messages: Belongs to the MHC class I family.

9739:CDK2AP1
gene id: 9739:CDK2AP1
uniprot id: A0A6J3PR54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDK2AP family.
messages: Nucleus

9739:LOC101332802
gene id: 9739:LOC101332802
uniprot id: A0A2U4BN90
uniprot id: A0A2U4BNG0
uniprot id: A0A6J3RVZ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9739:SCG2
gene id: 9739:SCG2
uniprot id: A0A2U4ADB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Interacts with Secretogranin III/SCG3.
messages: Neuroendocrine protein of the granin family that regulates the biogenesis of secretory granules.
messages: Secreted

9739:LOC109549580
gene id: 9739:LOC109549580
uniprot id: A0A6J3RCW8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9739:CFAP300
gene id: 9739:CFAP300
uniprot id: A0A2U3V1P6
uniprot id: A0A2U3V207
uniprot id: A0A6J3RT39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP300 family.
messages: Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. May play a role in outer and inner dynein arm assembly.
messages: Cytoplasm

9739:PEX7
gene id: 9739:PEX7
uniprot id: A0A2U4CPG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat peroxin-7 family.
messages: Peroxisome matrix
messages: cytosol

9739:SLC35F3
gene id: 9739:SLC35F3
uniprot id: A0A6J3Q754
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

9739:NSUN2
gene id: 9739:NSUN2
uniprot id: A0A2U3V227
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: extracellular exosome

9739:ALB
gene id: 9739:ALB
uniprot id: A0A2U3V5M2
uniprot id: A0A2U4B4Y4
uniprot id: A0A2U4B5B1
names: Subcellular Location Annotation
messages: Secreted

9739:BCAN
gene id: 9739:BCAN
uniprot id: A0A6J3QND1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aggrecan/versican proteoglycan family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9739:EPS8L3
gene id: 9739:EPS8L3
uniprot id: A0A6J3RU70
uniprot id: A0A6J3RUN0
uniprot id: A0A6J3RUY2
uniprot id: A0A6J3RUY9
names: Similarity
messages: Belongs to the EPS8 family.

9739:GABARAP
gene id: 9739:GABARAP
uniprot id: A0A2U3V7U9
names: Similarity
messages: Belongs to the ATG8 family.

9739:NAPSA
gene id: 9739:NAPSA
uniprot id: A0A6J3QCW9
names: Similarity
messages: Belongs to the peptidase A1 family.

9739:BTD
gene id: 9739:BTD
uniprot id: A0A6J3RBG5
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

9739:GRIK3
gene id: 9739:GRIK3
uniprot id: A0A6J3PUF5
uniprot id: A0A6J3PUV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

9739:OCSTAMP
gene id: 9739:OCSTAMP
uniprot id: A0A2U3V4J6
names: Subcellular Location Annotation
messages: Membrane

9739:SUCLA2
gene id: 9739:SUCLA2
uniprot id: A0A2U4BFZ4
uniprot id: A0A2U4BG02
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
messages: Belongs to the succinate/malate CoA ligase beta subunit family. ATP-specific subunit beta subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for ATP.
messages: Mitochondrion

9739:LOC101336709
gene id: 9739:LOC101336709
uniprot id: A0A6J3QYB7
uniprot id: A0A6J3QZ91
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit J family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. This subunit binds directly within the mRNA entry channel of the 40S ribosome to the aminoacyl (A) site. It may regulate the interaction between the 43S PIC and mRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.

9739:NR3C1
gene id: 9739:NR3C1
uniprot id: A0A6J3R399
uniprot id: A0A6J3R5L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Mitochondrion
messages: Nucleus
messages: centrosome
messages: spindle

9739:ELAC1
gene id: 9739:ELAC1
uniprot id: A0A2U4BHG2
names: Subunit
messages: Homodimer.

9739:NUDT3
gene id: 9739:NUDT3
uniprot id: A0A2U4C2C3
uniprot id: A0A2U4C2F5
names: Similarity
messages: Belongs to the Nudix hydrolase family. DIPP subfamily.

9739:AP3S2
gene id: 9739:AP3S2
uniprot id: A0A2U3UZZ0
uniprot id: A0A6J3R0M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

9739:CHAF1B
gene id: 9739:CHAF1B
uniprot id: A0A2U4ACP5
uniprot id: A0A6J3RBR1
names: Subcellular Location Annotation
messages: Nucleus

9739:KDM6A
gene id: 9739:KDM6A
uniprot id: A0A2U4C0R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTX family.
messages: Nucleus

9739:LOC101334257
gene id: 9739:LOC101334257
uniprot id: A0A6J3R089
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

9739:CASC1
gene id: 9739:CASC1
uniprot id: A0A2U4BFJ6
uniprot id: A0A6J3S7H5
names: Similarity
messages: Belongs to the DNAI7 family.

9739:MB21D2
gene id: 9739:MB21D2
uniprot id: A0A2U3V266
uniprot id: A0A2U4AC79
names: Similarity
messages: Belongs to the mab-21 family.

9739:ANKRD13C
gene id: 9739:ANKRD13C
uniprot id: A0A2U4A333
uniprot id: A0A2U4A341
names: Subcellular Location Annotation
messages: Membrane

9739:GABRG2
gene id: 9739:GABRG2
uniprot id: A0A2U4C645
uniprot id: A0A2U4C654
uniprot id: A0A6J3R3R8
uniprot id: A0A6J3R658
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRG2 sub-subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9739:CDPF1
gene id: 9739:CDPF1
uniprot id: A0A2U4B649
uniprot id: A0A2U4B654
uniprot id: A0A2U4B669
uniprot id: A0A2U4B6B6
uniprot id: A0A2U4B6J7
uniprot id: A0A2U4B6K2
names: Similarity
messages: Belongs to the CDPF1 family.

9739:LOC101321064
gene id: 9739:LOC101321064
uniprot id: A0A2U4C9E0
uniprot id: A0A2U4C9F1
names: Subcellular Location Annotation
messages: growth cone
messages: lamellipodium

9739:VDAC1
gene id: 9739:VDAC1
uniprot id: A0A2U4AGQ2
names: Similarity
messages: Belongs to the eukaryotic mitochondrial porin family.

9739:CDC25C
gene id: 9739:CDC25C
uniprot id: A0A2U4AGF3
uniprot id: A0A6J3R2X2
uniprot id: A0A6J3R315
uniprot id: A0A6J3R3S8
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

9739:KEG93 p08
gene id: 9739:KEG93_p08
uniprot id: B9UD81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
messages: Mitochondrion inner membrane

9739:SLC25A16
gene id: 9739:SLC25A16
uniprot id: A0A2U3V8J3
uniprot id: A0A2U4BEV0
uniprot id: A0A2U4BEV3
uniprot id: A0A2U4BEV4
uniprot id: A0A2U4BF89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9739:DYRK1B
gene id: 9739:DYRK1B
uniprot id: A0A6J3QFN2
uniprot id: A0A6J3QFN6
uniprot id: A0A6J3QGA2
uniprot id: A0A6J3QGA9
uniprot id: A0A6J3QGS4
uniprot id: A0A6J3QGS9
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

9739:LOC101339961
gene id: 9739:LOC101339961
uniprot id: A0A6J3RM90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. As part of the U7 snRNP it is involved in histone 3'-end processing.
messages: cytosol

9739:DGAT2L6
gene id: 9739:DGAT2L6
uniprot id: A0A2U4CG49
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:METTL8
gene id: 9739:METTL8
uniprot id: A0A2U4AAZ2
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.

9739:CSTF2
gene id: 9739:CSTF2
uniprot id: A0A6J3QSM9
uniprot id: A0A6J3QT95
uniprot id: A0A6J3QTG6
uniprot id: A0A6J3QTN4
uniprot id: A0A6J3QU97
names: Subcellular Location Annotation
messages: Nucleus

9739:SLC9A6
gene id: 9739:SLC9A6
uniprot id: A0A6J3QU47
uniprot id: A0A6J3QV18
uniprot id: A0A6J3QVT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Endosome membrane
messages: Recycling endosome membrane

9739:BVES
gene id: 9739:BVES
uniprot id: A0A2U3V138
names: Similarity
messages: Belongs to the popeye family.

9739:HTR1B
gene id: 9739:HTR1B
uniprot id: A0A2U4AUV1
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior. Besides, plays a role in vasoconstriction of cerebral arteries.
messages: Homodimer. Heterodimer with HTR1D.
messages: Ligands are bound in a hydrophobic pocket formed by the transmembrane helices.
messages: Membrane
messages: Palmitoylated.
messages: Phosphorylated.

9739:FAM83E
gene id: 9739:FAM83E
uniprot id: A0A6J3QE83
names: Similarity
messages: Belongs to the FAM83 family.

9739:CAPRIN1
gene id: 9739:CAPRIN1
uniprot id: A0A2U4CE32
uniprot id: A0A2U4CE33
uniprot id: A0A2U4CE41
names: Similarity
messages: Belongs to the caprin family.

9739:ADAM17
gene id: 9739:ADAM17
uniprot id: A0A2U4C071
uniprot id: A0A2U4C0F3
uniprot id: A0A6J3PV05
uniprot id: A0A6J3PVB4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:LOC117310273
gene id: 9739:LOC117310273
uniprot id: A0A6J3QSY9
names: Similarity
messages: Belongs to the serpin family.

9739:IL17RB
gene id: 9739:IL17RB
uniprot id: A0A6J3RYJ7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9739:ZKSCAN8
gene id: 9739:ZKSCAN8
uniprot id: A0A6J3RY86
names: Subcellular Location Annotation
messages: Nucleus

9739:IFNB1
gene id: 9739:IFNB1
uniprot id: A0A2U3V9R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

9739:RER1
gene id: 9739:RER1
uniprot id: A0A2U4CNA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RER1 family.
messages: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
messages: Membrane

9739:ARPP19
gene id: 9739:ARPP19
uniprot id: A0A6J3R0E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.

9739:LOC109549673
gene id: 9739:LOC109549673
uniprot id: A0A6J3R2U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

9739:FOXP1
gene id: 9739:FOXP1
uniprot id: A0A2U4CCF4
uniprot id: A0A6J3S2L8
uniprot id: A0A6J3S2V8
uniprot id: A0A6J3S3G8
uniprot id: A0A6J3S3T1
names: Subcellular Location Annotation
messages: Nucleus

9739:KEG93 p10
gene id: 9739:KEG93_p10
uniprot id: B9UD79
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

9739:PCSK4
gene id: 9739:PCSK4
uniprot id: A0A6J3R9F2
names: Similarity
messages: Belongs to the peptidase S8 family.

9739:GHITM
gene id: 9739:GHITM
uniprot id: A0A2U4AKJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

9739:SLC24A1
gene id: 9739:SLC24A1
uniprot id: A0A6J3QSW2
uniprot id: O62805
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

9739:LOC101323507
gene id: 9739:LOC101323507
uniprot id: A0A2U4BZ79
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

9739:INSL5
gene id: 9739:INSL5
uniprot id: A0A2U3V6U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

9739:BRS3
gene id: 9739:BRS3
uniprot id: A0A2U3V9X5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with C6orf89.
messages: Membrane

9739:KRT78
gene id: 9739:KRT78
uniprot id: A0A6J3S691
names: Similarity
messages: Belongs to the intermediate filament family.

9739:GUCY2F
gene id: 9739:GUCY2F
uniprot id: A0A2U4CHT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane
messages: Photoreceptor outer segment membrane

9739:SCT
gene id: 9739:SCT
uniprot id: A0A6J3RSS3
names: Similarity
messages: Belongs to the glucagon family.

9739:SCN3B
gene id: 9739:SCN3B
uniprot id: A0A2U4BVY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel auxiliary subunit SCN3B (TC 8.A.17) family.
messages: Membrane
messages: Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.

9739:HABP2
gene id: 9739:HABP2
uniprot id: A0A2U4BQV1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9739:LAMTOR3
gene id: 9739:LAMTOR3
uniprot id: A0A6J3RER1
uniprot id: A0A6J3RER9
uniprot id: A0A6J3REU2
uniprot id: A0A6J3RF99
uniprot id: A0A6J3RFK6
uniprot id: A0A6J3RH24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMTOR3 family.
messages: Endosome membrane
messages: Late endosome membrane

9739:NDUFS8
gene id: 9739:NDUFS8
uniprot id: A0A6J3RRG1
uniprot id: A0A6J3RS38
names: Similarity
messages: Belongs to the complex I 23 kDa subunit family.

9739:PLPPR3
gene id: 9739:PLPPR3
uniprot id: A0A6J3R994
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

9739:CRTC2
gene id: 9739:CRTC2
uniprot id: A0A6J3RI32
uniprot id: A0A6J3RIA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TORC family.
messages: Cytoplasm
messages: Nucleus

9739:OXCT1
gene id: 9739:OXCT1
uniprot id: A0A2U4AXE6
uniprot id: A0A2U4AXF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
messages: Mitochondrion

9739:ERP29
gene id: 9739:ERP29
uniprot id: A0A2U3V854
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Does not seem to be a disulfide isomerase.
messages: Endoplasmic reticulum lumen
messages: Homodimer.
messages: Melanosome

9739:BID
gene id: 9739:BID
uniprot id: A0A6J3S9R8
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Forms heterodimers either with the pro-apoptotic protein BAX or the anti-apoptotic protein BCL2.
messages: Induces caspases and apoptosis. Counters the protective effect of BCL2.
messages: Intact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family.
messages: Membrane
messages: Mitochondrion outer membrane

9739:IDUA
gene id: 9739:IDUA
uniprot id: A0A6J3RC14
uniprot id: A0A6J3RC19
uniprot id: A0A6J3RC71
uniprot id: A0A6J3RC75
uniprot id: A0A6J3RCY6
uniprot id: A0A6J3RCZ1
uniprot id: A0A6J3REJ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

9739:DNM1L
gene id: 9739:DNM1L
uniprot id: A0A2U4BCK8
uniprot id: A0A2U4BCM5
uniprot id: A0A2U4BCN4
uniprot id: A0A2U4BCS6
uniprot id: A0A2U4BCT1
uniprot id: A0A2U4BCZ1
uniprot id: A0A2U4BD31
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

9739:C11H12orf75
gene id: 9739:C11H12orf75
uniprot id: A0A2U3V813
names: Similarity
messages: Belongs to the OCC1 family.

9739:LOC101324470
gene id: 9739:LOC101324470
uniprot id: A0A2U4CH42
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9739:SYT1
gene id: 9739:SYT1
uniprot id: A0A2U4CQP7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: synaptic vesicle membrane

9739:MFSD6L
gene id: 9739:MFSD6L
uniprot id: A0A2U4C352
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. MFSD6 family.
messages: Membrane

9739:EHD1
gene id: 9739:EHD1
uniprot id: A0A2U4CAZ1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

9739:LOC101316738
gene id: 9739:LOC101316738
uniprot id: A0A2U4CPR0
uniprot id: A0A2U4CPR4
uniprot id: A0A2U4CPR5
uniprot id: A0A2U4CPR8
uniprot id: A0A2U4CPR9
uniprot id: A0A2U4CQ24
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

9739:FAM187A
gene id: 9739:FAM187A
uniprot id: A0A6J3QR74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM187 family.
messages: Membrane

9739:AP1S2
gene id: 9739:AP1S2
uniprot id: A0A2U4AJL9
uniprot id: A0A2U4AK65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: Membrane
messages: clathrin-coated pit

9739:LOC101328481
gene id: 9739:LOC101328481
uniprot id: A0A2U3V4S0
names: Similarity
messages: Belongs to the serpin family.

9739:LOC101332835
gene id: 9739:LOC101332835
uniprot id: A0A2U4A8Z1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADPH--cytochrome P450 reductase family.
messages: Binds 1 FAD per monomer.
messages: Binds 1 FMN per monomer.
messages: Endoplasmic reticulum membrane
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5.

9739:LOC117309094
gene id: 9739:LOC117309094
uniprot id: A0A6J3QVJ7
names: Function
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.
messages: Metallothioneins have a high content of cysteine residues that bind various heavy metals.

9739:NDFIP2
gene id: 9739:NDFIP2
uniprot id: A0A2U4A6K6
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

9739:LOC117308644
gene id: 9739:LOC117308644
uniprot id: A0A6J3Q8M7
names: Subcellular Location Annotation
messages: Membrane

9739:RAB3IL1
gene id: 9739:RAB3IL1
uniprot id: A0A6J3RPN0
names: Similarity
messages: Belongs to the SEC2 family.

9739:LOC101323115
gene id: 9739:LOC101323115
uniprot id: A0A6J3QCN8
names: Caution
names: Function
names: Similarity
messages: As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.
messages: Belongs to the peptidase S1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:LOC117313916
gene id: 9739:LOC117313916
uniprot id: A0A2U3V6I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UPF0729 family.
messages: Interacts with DERL1 and AMFR.
messages: Lipid droplet
messages: May activate the NF-kappa-B signaling pathway.

9739:RPL39
gene id: 9739:RPL39
uniprot id: A0A2U4CI53
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

9739:TMC2
gene id: 9739:TMC2
uniprot id: A0A6J3Q3Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

9739:MBP
gene id: 9739:MBP
uniprot id: A0A6J3PUU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin basic protein family.
messages: Myelin membrane

9739:RAB19
gene id: 9739:RAB19
uniprot id: A0A2U4AZN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane

9739:LOC101317589
gene id: 9739:LOC101317589
uniprot id: A0A6J3QTV5
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

9739:LOC101321910
gene id: 9739:LOC101321910
uniprot id: A0A6J3R1H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

9739:CRYBB3
gene id: 9739:CRYBB3
uniprot id: A0A2U4CKT0
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

9739:LOC117310213
gene id: 9739:LOC117310213
uniprot id: A0A6J3QRT8
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

9739:ITPKA
gene id: 9739:ITPKA
uniprot id: A0A2U4BCE6
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

9739:SLC39A11
gene id: 9739:SLC39A11
uniprot id: A0A6J3QPN0
uniprot id: A0A6J3QPN6
uniprot id: A0A6J3QPT0
uniprot id: A0A6J3QPT6
uniprot id: A0A6J3QQB6
uniprot id: A0A6J3QQC1
uniprot id: A0A6J3QQH7
uniprot id: A0A6J3QQI2
uniprot id: A0A6J3QQV2
names: Subcellular Location Annotation
messages: Membrane

9739:RPL37
gene id: 9739:RPL37
uniprot id: A0A2U3V631
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

9739:PFAS
gene id: 9739:PFAS
uniprot id: A0A6J3QJL2
uniprot id: A0A6J3QJP4
uniprot id: A0A6J3QK94
uniprot id: A0A6J3QKR1
names: Similarity
messages: In the N-terminal section; belongs to the FGAMS family.

9739:PDGFC
gene id: 9739:PDGFC
uniprot id: A0A6J3REX0
uniprot id: A0A6J3REZ3
uniprot id: A0A6J3RFE8
uniprot id: A0A6J3RFQ5
uniprot id: A0A6J3RH75
names: Caution
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:LOC109548336
gene id: 9739:LOC109548336
uniprot id: A0A6J3Q9F8
names: Subcellular Location Annotation
messages: Cell membrane

9739:SASS6
gene id: 9739:SASS6
uniprot id: A0A2U4A1C0
uniprot id: A0A2U4A1C2
uniprot id: A0A2U4A1C3
uniprot id: A0A2U4A1C4
uniprot id: A0A2U4A2B0
uniprot id: A0A6J3RW88
uniprot id: A0A6J3RW95
uniprot id: A0A6J3RWV7
uniprot id: A0A6J3RWW2
names: Subcellular Location Annotation
messages: centrosome

9739:SLCO2A1
gene id: 9739:SLCO2A1
uniprot id: A0A2U4B947
uniprot id: A0A2U4B959
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:SNU13
gene id: 9739:SNU13
uniprot id: A0A6J3S5K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

9739:RAB21
gene id: 9739:RAB21
uniprot id: A0A2U4CRS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cleavage furrow
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: trans-Golgi network

9739:HEBP1
gene id: 9739:HEBP1
uniprot id: A0A6J3S7V2
uniprot id: A0A6J3S928
names: Similarity
messages: Belongs to the HEBP family.

9739:RTF2
gene id: 9739:RTF2
uniprot id: A0A2U4C245
uniprot id: A0A2U4C287
names: Similarity
names: Subunit
messages: Belongs to the rtf2 family.
messages: Interacts with DDI2; probably also interacts with DDI1.

9739:LOC101318394
gene id: 9739:LOC101318394
uniprot id: A0A2U3V2J4
uniprot id: A0A2U4BJ95
uniprot id: A0A2U4BJF6
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

9739:FOXD3
gene id: 9739:FOXD3
uniprot id: A0A2U4A197
names: Subcellular Location Annotation
messages: Nucleus

9739:PIK3C3
gene id: 9739:PIK3C3
uniprot id: A0A2U4AY70
uniprot id: A0A2U4AY83
uniprot id: A0A2U4AYA7
uniprot id: A0A2U4AYN7
uniprot id: A0A6J3PTZ4
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

9739:GASK1A
gene id: 9739:GASK1A
uniprot id: A0A2U4CAK3
uniprot id: A0A6J3S0W3
names: Similarity
messages: Belongs to the GASK family.

9739:MPV17L
gene id: 9739:MPV17L
uniprot id: A0A6J3Q1F7
uniprot id: A0A6J3Q1K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

9739:SIX3
gene id: 9739:SIX3
uniprot id: A0A6J3PW80
names: Subcellular Location Annotation
messages: Nucleus

9739:LOC101330884
gene id: 9739:LOC101330884
uniprot id: A0A6J3PWB7
names: Similarity
messages: Belongs to the SNURF family.

9739:NETO1
gene id: 9739:NETO1
uniprot id: A0A6J3PUP4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:TLCD2
gene id: 9739:TLCD2
uniprot id: A0A2U3V9Y8
names: Subcellular Location Annotation
messages: Membrane

9739:ST7
gene id: 9739:ST7
uniprot id: A0A2U4AHP0
uniprot id: A0A2U4AHT2
uniprot id: A0A2U4AHW5
uniprot id: A0A2U4AHX0
uniprot id: A0A2U4AHY6
uniprot id: A0A2U4AI80
uniprot id: A0A2U4AIA0
uniprot id: A0A6J3RWX5
uniprot id: A0A6J3RX11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ST7 family.
messages: Membrane

9739:KIF20B
gene id: 9739:KIF20B
uniprot id: A0A2U4BXC8
uniprot id: A0A6J3Q522
uniprot id: A0A6J3Q524
uniprot id: A0A6J3Q529
uniprot id: A0A6J3Q5A6
uniprot id: A0A6J3Q5J2
uniprot id: A0A6J3Q5U7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9739:SH3RF3
gene id: 9739:SH3RF3
uniprot id: A0A2U4B0Z4
names: Similarity
messages: Belongs to the SH3RF family.

9739:SPA17
gene id: 9739:SPA17
uniprot id: A0A2U4BVP9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates.

9739:PSMB10
gene id: 9739:PSMB10
uniprot id: A0A6J3QFK0
uniprot id: A0A6J3QFK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

9739:LOC101315542
gene id: 9739:LOC101315542
uniprot id: A0A2U4CF79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9739:KNG1
gene id: 9739:KNG1
uniprot id: A0A2U3V5S9
uniprot id: A0A2U4C806
names: Subcellular Location Annotation
messages: extracellular space

9739:TMEM30B
gene id: 9739:TMEM30B
uniprot id: A0A2U4ACG5
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

9739:COL4A2
gene id: 9739:COL4A2
uniprot id: A0A6J3QA40
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

9739:SHH
gene id: 9739:SHH
uniprot id: A0A6J3RVS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

9739:G6PC2
gene id: 9739:G6PC2
uniprot id: A0A2U3V6F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

9739:ICAM1
gene id: 9739:ICAM1
uniprot id: A0A6J3R624
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. ICAM family.
messages: Membrane

9739:DDX55
gene id: 9739:DDX55
uniprot id: A0A2U3V793
uniprot id: A0A2U3V7M6
uniprot id: A0A2U4CK21
uniprot id: A0A2U4CK22
uniprot id: A0A2U4CK94
uniprot id: A0A6J3PRN4
uniprot id: A0A6J3PS59
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

9739:ERLIN1
gene id: 9739:ERLIN1
uniprot id: A0A2U4BQ83
uniprot id: A0A2U4BQ87
uniprot id: A0A2U4BQD8
uniprot id: A0A2U4BQE3
uniprot id: A0A2U4BQK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the band 7/mec-2 family.
messages: Endoplasmic reticulum membrane
messages: Mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway.
messages: Membrane

9739:PLAT
gene id: 9739:PLAT
uniprot id: A0A2U4A827
uniprot id: A0A6J3QQF3
uniprot id: A0A6J3QR49
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9739:MICAL3
gene id: 9739:MICAL3
uniprot id: A0A2U4AK95
uniprot id: A0A2U4AK97
uniprot id: A0A2U4AKA1
uniprot id: A0A2U4AKB0
uniprot id: A0A2U4AKE5
uniprot id: A0A2U4AKF1
uniprot id: A0A2U4AKS4
uniprot id: A0A2U4AKS9
uniprot id: A0A6J3S804
uniprot id: A0A6J3S9M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Cytoplasm

9739:SLC5A7
gene id: 9739:SLC5A7
uniprot id: A0A2U3UZH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

9739:SRPX2
gene id: 9739:SRPX2
uniprot id: A0A2U4B3J9
uniprot id: A0A6J3QRQ3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:NOP58
gene id: 9739:NOP58
uniprot id: A0A2U3V5R7
uniprot id: A0A2U4BN68
uniprot id: A0A2U4BN79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

9739:INSIG2
gene id: 9739:INSIG2
uniprot id: A0A2U4B2K7
uniprot id: A0A2U4B2R4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Mediates feedback control of cholesterol synthesis.
messages: Membrane

9739:IMPACT
gene id: 9739:IMPACT
uniprot id: A0A2U4AYK0
uniprot id: A0A2U4AYK2
uniprot id: A0A2U4AYM6
uniprot id: A0A2U4AZ07
uniprot id: A0A6J3PTL9
uniprot id: A0A6J3PTT6
uniprot id: A0A6J3PU67
uniprot id: A0A6J3PU90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IMPACT family.
messages: Cytoplasm

9739:LOC101328963
gene id: 9739:LOC101328963
uniprot id: A0A6J3RF09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

9739:VCAM1
gene id: 9739:VCAM1
uniprot id: A0A2U3V9Q1
names: Subcellular Location Annotation
messages: Cell membrane

9739:TAF6L
gene id: 9739:TAF6L
uniprot id: A0A2U4B4M1
uniprot id: A0A2U4B508
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

9739:LOC101329441
gene id: 9739:LOC101329441
uniprot id: A0A2U3V3H1
names: Subcellular Location Annotation
messages: Membrane

9739:NAA11
gene id: 9739:NAA11
uniprot id: A0A2U4B4Y0
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

9739:B4GALT6
gene id: 9739:B4GALT6
uniprot id: A0A2U3V0L0
uniprot id: A0A2U4AYG2
uniprot id: A0A6J3PTM9
uniprot id: A0A6J3PTU5
uniprot id: A0A6J3PUA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

9739:LOC109547272
gene id: 9739:LOC109547272
uniprot id: A0A6J3QUK1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

9739:PHOX2A
gene id: 9739:PHOX2A
uniprot id: A0A6J3RUV0
names: Subcellular Location Annotation
messages: Nucleus

9739:HCRTR1
gene id: 9739:HCRTR1
uniprot id: A0A6J3PYL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9739:CAST
gene id: 9739:CAST
uniprot id: A0A2U4AW78
uniprot id: A0A2U4AW85
uniprot id: A0A2U4AW91
uniprot id: A0A2U4AW92
uniprot id: A0A2U4AW96
uniprot id: A0A2U4AWA5
uniprot id: A0A2U4AWB0
uniprot id: A0A2U4AWB5
uniprot id: A0A2U4AWQ4
uniprot id: A0A2U4AWQ9
uniprot id: A0A6J3R2H6
uniprot id: A0A6J3R2L5
names: Function
names: Similarity
messages: Belongs to the protease inhibitor I27 (calpastatin) family.
messages: Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue.

9739:PLK1
gene id: 9739:PLK1
uniprot id: A0A6J3Q009
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
messages: Midbody
messages: Nucleus
messages: centrosome

9739:ADAMDEC1
gene id: 9739:ADAMDEC1
uniprot id: A0A2U4BUY5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:KCNAB1
gene id: 9739:KCNAB1
uniprot id: A0A2U4C8L0
uniprot id: A0A2U4C8L1
uniprot id: A0A2U4C8L3
uniprot id: A0A2U4C8M7
uniprot id: A0A2U4C8U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

9739:FZR1
gene id: 9739:FZR1
uniprot id: A0A6J3R764
uniprot id: A0A6J3R7A3
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

9739:HEPHL1
gene id: 9739:HEPHL1
uniprot id: A0A6J3RSR0
names: Similarity
messages: Belongs to the multicopper oxidase family.

9739:ACTN2
gene id: 9739:ACTN2
uniprot id: A0A6J3Q5M4
names: Similarity
messages: Belongs to the alpha-actinin family.

9739:LOC101337597
gene id: 9739:LOC101337597
uniprot id: A0A2U4C3B0
names: Similarity
messages: Belongs to the TACO1 family.

9739:RPL9
gene id: 9739:RPL9
uniprot id: A0A2U3V1C6
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

9739:DOK1
gene id: 9739:DOK1
uniprot id: A0A6J3PVB1
names: Similarity
messages: Belongs to the DOK family. Type A subfamily.

9739:CPB1
gene id: 9739:CPB1
uniprot id: A0A2U4B944
names: Similarity
messages: Belongs to the peptidase M14 family.

9739:NCDN
gene id: 9739:NCDN
uniprot id: A0A6J3PVB6
uniprot id: A0A6J3PVD5
uniprot id: A0A6J3PVL7
uniprot id: A0A6J3PW09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurochondrin family.
messages: Postsynapse

9739:ACTA1
gene id: 9739:ACTA1
uniprot id: A0A2U4BVD6
uniprot id: A0A2U4BVL2
names: Similarity
messages: Belongs to the actin family.

9739:MARCHF11
gene id: 9739:MARCHF11
uniprot id: A0A2U4CMD9
names: Subcellular Location Annotation
messages: Membrane

9739:CPZ
gene id: 9739:CPZ
uniprot id: A0A6J3RCJ8
uniprot id: A0A6J3RD45
uniprot id: A0A6J3REX5
names: Caution
names: Similarity
messages: Belongs to the peptidase M14 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:LOC101324002
gene id: 9739:LOC101324002
uniprot id: A0A6J3QP34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: myofibril

9739:LOC117313811
gene id: 9739:LOC117313811
uniprot id: A0A6J3QVI1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Component of the 40S small ribosomal subunit.

9739:SH2B2
gene id: 9739:SH2B2
uniprot id: A0A6J3Q1H2
uniprot id: A0A6J3Q1H4
uniprot id: A0A6J3Q1M0
names: Similarity
messages: Belongs to the SH2B adapter family.

9739:REXO4
gene id: 9739:REXO4
uniprot id: A0A6J3RJR1
uniprot id: A0A6J3RJU4
uniprot id: A0A6J3RKM1
uniprot id: A0A6J3RLI6
names: Similarity
messages: Belongs to the REXO4 family.

9739:TMEM234
gene id: 9739:TMEM234
uniprot id: A0A6J3PXX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM234 family.
messages: Membrane

9739:NUP155
gene id: 9739:NUP155
uniprot id: A0A2U4AXJ5
uniprot id: A0A2U4AY05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the non-repetitive/WGA-negative nucleoporin family.
messages: nuclear pore complex

9739:HOXB2
gene id: 9739:HOXB2
uniprot id: A0A6J3QLP3
names: Subcellular Location Annotation
messages: Nucleus

9739:LPXN
gene id: 9739:LPXN
uniprot id: A0A2U4CET1
uniprot id: A0A6J3RPY6
uniprot id: A0A6J3RQL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paxillin family.
messages: focal adhesion

9739:LOC101330662
gene id: 9739:LOC101330662
uniprot id: A0A6J3S510
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Rough endoplasmic reticulum

9739:EOMES
gene id: 9739:EOMES
uniprot id: A0A2U4C9U3
uniprot id: A0A2U4C9U9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9739:TMEM98
gene id: 9739:TMEM98
uniprot id: A0A2U3V2E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM98 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: extracellular exosome

9739:LOC101326278
gene id: 9739:LOC101326278
uniprot id: A0A2U3V856
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9739:TRIM54
gene id: 9739:TRIM54
uniprot id: A0A6J3PVQ9
names: Function
names: Subcellular Location Annotation
messages: May bind and stabilize microtubules during myotubes formation.
messages: Z line

9739:PCK1
gene id: 9739:PCK1
uniprot id: A0A6J3Q2K2
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.

9739:LOC101338325
gene id: 9739:LOC101338325
uniprot id: A0A2U4AGI5
uniprot id: A0A6J3R2V0
uniprot id: A0A6J3R2Z1
uniprot id: A0A6J3R3E8
uniprot id: A0A6J3R3P7
uniprot id: A0A6J3R528
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.

9739:LOC109548827
gene id: 9739:LOC109548827
uniprot id: A0A6J3RDX6
uniprot id: A0A6J3REI3
uniprot id: A0A6J3RG84
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.

9739:PFN4
gene id: 9739:PFN4
uniprot id: A0A2U3VAI5
names: Similarity
messages: Belongs to the profilin family.

9739:MAPK8IP2
gene id: 9739:MAPK8IP2
uniprot id: A0A6J3S4U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JIP scaffold family.
messages: Cytoplasm

9739:LOC109551787
gene id: 9739:LOC109551787
uniprot id: A0A6J3R070
names: Similarity
messages: Belongs to the heat shock protein 70 family.

9739:TACR1
gene id: 9739:TACR1
uniprot id: A0A6J3PVW9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with ARRB1.
messages: Membrane

9739:OVCH2
gene id: 9739:OVCH2
uniprot id: A0A6J3RT89
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:NDUFB7
gene id: 9739:NDUFB7
uniprot id: A0A6J3R5P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB7 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

9739:LOC101334994
gene id: 9739:LOC101334994
uniprot id: A0A6J3R6V7
uniprot id: A0A6J3R6Z0
names: Similarity
messages: Belongs to the perilipin family.

9739:NOP56
gene id: 9739:NOP56
uniprot id: A0A2U4CLW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

9739:P3H2
gene id: 9739:P3H2
uniprot id: A0A2U3V0Y7
uniprot id: A0A2U4C8S5
names: Similarity
messages: Belongs to the leprecan family.

9739:CCDC167
gene id: 9739:CCDC167
uniprot id: A0A6J3S0I9
names: Subcellular Location Annotation
messages: Membrane

9739:NKX1-1
gene id: 9739:NKX1-1
uniprot id: A0A2U4CNA1
names: Subcellular Location Annotation
messages: Nucleus

9739:SPEG
gene id: 9739:SPEG
uniprot id: A0A6J3RL80
uniprot id: A0A6J3RL84
uniprot id: A0A6J3RLM7
uniprot id: A0A6J3RLN3
uniprot id: A0A6J3RLV9
uniprot id: A0A6J3RMK7
uniprot id: A0A6J3RN06
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

9739:LOC109551910
gene id: 9739:LOC109551910
uniprot id: A0A6J3R9D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing.
messages: cytosol

9739:GRAMD1B
gene id: 9739:GRAMD1B
uniprot id: A0A6J3RSZ6
uniprot id: A0A6J3RT83
uniprot id: A0A6J3RTJ6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:LOC109552396
gene id: 9739:LOC109552396
uniprot id: A0A6J3RHR9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9739:DDX50
gene id: 9739:DDX50
uniprot id: A0A2U3VAL0
uniprot id: A0A6J3Q6B8
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.

9739:PTGES2
gene id: 9739:PTGES2
uniprot id: A0A6J3RIK7
uniprot id: A0A6J3RIW0
uniprot id: A0A6J3RKK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GST superfamily.
messages: Membrane

9739:HAAO
gene id: 9739:HAAO
uniprot id: A0A6J3PWS9
uniprot id: A0A6J3PX29
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 3-HAO family.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

9739:CDCA2
gene id: 9739:CDCA2
uniprot id: A0A2U3V423
uniprot id: A0A6J3RFI8
uniprot id: A0A6J3RFM8
uniprot id: A0A6J3RG10
uniprot id: A0A6J3RG16
uniprot id: A0A6J3RHS2
names: Subcellular Location Annotation
messages: Nucleus

9739:SLC9A4
gene id: 9739:SLC9A4
uniprot id: A0A2U4B042
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Interacts with CHP1 and CHP2.
messages: Membrane

9739:LOC101330589
gene id: 9739:LOC101330589
uniprot id: A0A2U4ABB6
uniprot id: A0A6J3RML1
names: Subcellular Location Annotation
messages: Membrane

9739:CHMP1A
gene id: 9739:CHMP1A
uniprot id: A0A6J3QDZ5
uniprot id: A0A6J3QE04
names: Similarity
messages: Belongs to the SNF7 family.

9739:TMEM129
gene id: 9739:TMEM129
uniprot id: A0A2U4CN37
uniprot id: A0A6J3RCU0
uniprot id: A0A6J3REM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM129 family.
messages: Membrane

9739:CRH
gene id: 9739:CRH
uniprot id: A0A2U3V8T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

9739:LOC117314122
gene id: 9739:LOC117314122
uniprot id: A0A6J3S3P8
names: Similarity
messages: Belongs to the potassium channel KCNE family.

9739:INKA2
gene id: 9739:INKA2
uniprot id: A0A6J3RTA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INKA family.
messages: Nucleus

9739:NCBP3
gene id: 9739:NCBP3
uniprot id: A0A2U3V2N9
uniprot id: A0A2U4AN93
uniprot id: A0A2U4AN99
uniprot id: A0A2U4ANC1
uniprot id: A0A6J3QN58
names: Similarity
messages: Belongs to the NCBP3 family.

9739:IL26
gene id: 9739:IL26
uniprot id: A0A2U4CQJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

9739:ATP5F1C
gene id: 9739:ATP5F1C
uniprot id: A0A2U3V6X1
uniprot id: A0A2U3V799
uniprot id: A0A2U4B6F4
uniprot id: A0A2U4B6T2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

9739:SLC26A10
gene id: 9739:SLC26A10
uniprot id: A0A6J3S5L3
uniprot id: A0A6J3S5U3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:ECHDC2
gene id: 9739:ECHDC2
uniprot id: A0A2U4BJD6
uniprot id: A0A2U4BJE3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

9739:THG1L
gene id: 9739:THG1L
uniprot id: A0A2U3VAK7
names: Cofactor
names: Function
names: Similarity
messages: Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
messages: Belongs to the tRNA(His) guanylyltransferase family.
messages: Binds 2 magnesium ions per subunit.

9739:CAPZA1
gene id: 9739:CAPZA1
uniprot id: A0A2U4A217
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

9739:MPV17
gene id: 9739:MPV17
uniprot id: A0A2U3V4R2
uniprot id: A0A6J3PXI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

9739:YPEL2
gene id: 9739:YPEL2
uniprot id: A0A2U4C6J0
names: Similarity
messages: Belongs to the yippee family.

9739:IL6
gene id: 9739:IL6
uniprot id: A0A2U3V9U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-6 superfamily.
messages: Component of a hexamer of two molecules each of IL6, IL6R and IL6ST; first binds to IL6R to associate with the signaling subunit IL6ST. Interacts with IL6R (via the N-terminal ectodomain); this interaction may be affected by IL6R-binding with SORL1, hence decreasing IL6 cis signaling. Interacts with SORL1 (via the N-terminal ectodomain); this interaction leads to IL6 internalization and lysosomal degradation. May form a trimeric complex with the soluble SORL1 ectodomain and soluble IL6R receptor; this interaction might stabilize circulating IL6, hence promoting IL6 trans signaling.
messages: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway. The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells.
messages: IL6 is a potent inducer of the acute phase response. Rapid production of IL6 contributes to host defense during infection and tissue injury, but excessive IL6 synthesis is involved in disease pathology. In the innate immune response, is synthesized by myeloid cells, such as macrophages and dendritic cells, upon recognition of pathogens through toll-like receptors (TLRs) at the site of infection or tissue injury (By similarity). In the adaptive immune response, is required for the differentiation of B cells into immunoglobulin-secreting cells. Plays a major role in the differentiation of CD4(+) T cell subsets. Essential factor for the development of T follicular helper (Tfh) cells that are required for the induction of germinal-center formation. Required to drive naive CD4(+) T cells to the Th17 lineage. Also required for proliferation of myeloma cells and the survival of plasmablast cells.
messages: Secreted

9739:NAE1
gene id: 9739:NAE1
uniprot id: A0A2U4BDH2
uniprot id: A0A2U4BDH4
uniprot id: A0A2U4BDI7
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
messages: Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M.

9739:LOC117309540
gene id: 9739:LOC117309540
uniprot id: A0A6J3QNC1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9739:LHFPL6
gene id: 9739:LHFPL6
uniprot id: A0A2U4BGB3
uniprot id: A0A6J3QAG4
names: Subcellular Location Annotation
messages: Membrane

9739:SIX6
gene id: 9739:SIX6
uniprot id: A0A2U3V6D8
names: Subcellular Location Annotation
messages: Nucleus

9739:MINDY3
gene id: 9739:MINDY3
uniprot id: A0A2U4B757
uniprot id: A0A2U4B762
uniprot id: A0A6J3R1D8
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
messages: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

9739:DSG2
gene id: 9739:DSG2
uniprot id: A0A2U4AYF9
uniprot id: A0A2U4AYG0
uniprot id: A0A2U4AYH3
uniprot id: A0A2U4AYJ6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: desmosome

9739:KDELR1
gene id: 9739:KDELR1
uniprot id: A0A6J3QIB2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:RASGRP4
gene id: 9739:RASGRP4
uniprot id: A0A6J3QE91
uniprot id: A0A6J3QES0
uniprot id: A0A6J3QES2
uniprot id: A0A6J3QES6
uniprot id: A0A6J3QF82
names: Similarity
messages: Belongs to the RASGRP family.

9739:VIL1
gene id: 9739:VIL1
uniprot id: A0A6J3RN60
names: Similarity
messages: Belongs to the villin/gelsolin family.

9739:PPBP
gene id: 9739:PPBP
uniprot id: A0A2U3V3Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

9739:IGF2
gene id: 9739:IGF2
uniprot id: A0A6J3RRV6
uniprot id: A0A6J3RSF5
uniprot id: A0A6J3RSJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the insulin family.
messages: Interacts with MYORG; this interaction is required for IGF2 secretion. Interacts with integrins ITGAV:ITGB3 and ITGA6:ITGB4; integrin-binding is required for IGF2 signaling.
messages: Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.
messages: Secreted
messages: The insulin-like growth factors possess growth-promoting activity (By similarity). Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development. IGF2 is influenced by placental lactogen. Also involved in tissue differentiation. In adults, involved in glucose metabolism in adipose tissue, skeletal muscle and liver. Acts as a ligand for integrin which is required for IGF2 signaling. Positively regulates myogenic transcription factor MYOD1 function by facilitating the recruitment of transcriptional coactivators, thereby controlling muscle terminal differentiation (By similarity). Inhibits myoblast differentiation and modulates metabolism via increasing the mitochondrial respiration rate.

9739:LOC101335257
gene id: 9739:LOC101335257
uniprot id: A0A6J3RSM7
names: Subcellular Location Annotation
messages: Membrane

9739:SUMO1
gene id: 9739:SUMO1
uniprot id: A0A2U4BND3
uniprot id: A0A6J3RNG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

9739:TMSB15A
gene id: 9739:TMSB15A
uniprot id: A0A2U3V932
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

9739:CD28
gene id: 9739:CD28
uniprot id: A0A2U3V176
names: Subcellular Location Annotation
messages: Membrane

9739:NDUFA8
gene id: 9739:NDUFA8
uniprot id: A0A2U3V7B5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I NDUFA8 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion intermembrane space

9739:GPR1
gene id: 9739:GPR1
uniprot id: A0A2U3V429
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

9739:CKAP2L
gene id: 9739:CKAP2L
uniprot id: A0A2U3V5N9
names: Similarity
messages: Belongs to the CKAP2 family.

9739:SYT15
gene id: 9739:SYT15
uniprot id: A0A2U4AJW8
uniprot id: A0A2U4AK33
uniprot id: A0A6J3Q7P8
uniprot id: A0A6J3Q8J0
names: Similarity
messages: Belongs to the synaptotagmin family.

9739:KCNH7
gene id: 9739:KCNH7
uniprot id: A0A2U4AAB0
names: Subcellular Location Annotation
messages: Membrane

9739:FAM178B
gene id: 9739:FAM178B
uniprot id: A0A6J3PWP3
names: Similarity
messages: Belongs to the FAM178 family.

9739:LOC101337437
gene id: 9739:LOC101337437
uniprot id: A0A6J3R200
names: Similarity
messages: Belongs to the cytochrome P450 family.

9739:NUP188
gene id: 9739:NUP188
uniprot id: A0A2U4CH98
uniprot id: A0A2U4CHA3
uniprot id: A0A2U4CHA9
names: Subcellular Location Annotation
messages: nuclear pore complex

9739:NMUR2
gene id: 9739:NMUR2
uniprot id: A0A2U3V359
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

9739:C13H12orf49
gene id: 9739:C13H12orf49
uniprot id: A0A6J3PRM3
uniprot id: A0A6J3PRS7
uniprot id: A0A6J3PS73
uniprot id: A0A6J3PSR7
uniprot id: A0A6J3PSS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPRING family.
messages: Golgi apparatus membrane
messages: Membrane

9739:CENPK
gene id: 9739:CENPK
uniprot id: A0A2U3V5D4
uniprot id: A0A6J3R278
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-K/MCM22 family.
messages: Nucleus
messages: centromere

9739:KLC3
gene id: 9739:KLC3
uniprot id: A0A6J3QEX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

9739:CKAP2
gene id: 9739:CKAP2
uniprot id: A0A2U3V7Z1
names: Similarity
messages: Belongs to the CKAP2 family.

9739:HTR1E
gene id: 9739:HTR1E
uniprot id: A0A2U3V6Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9739:LTBP1
gene id: 9739:LTBP1
uniprot id: A0A2U4C001
uniprot id: A0A2U4C002
uniprot id: A0A2U4C046
uniprot id: A0A2U4C050
uniprot id: A0A2U4C089
uniprot id: A0A6J3PX22
uniprot id: A0A6J3PX24
uniprot id: A0A6J3PX28
uniprot id: A0A6J3PX88
uniprot id: A0A6J3PXB3
uniprot id: A0A6J3PXQ5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9739:SLC35F6
gene id: 9739:SLC35F6
uniprot id: A0A6J3PXI0
uniprot id: A0A6J3PXM1
uniprot id: A0A6J3PXS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLC35F solute transporter family.
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Interacts with SLC25A5.
messages: May play a role as a nucleotide-sugar transporter.
messages: Membrane
messages: Mitochondrion

9739:ATL1
gene id: 9739:ATL1
uniprot id: A0A2U4AEU4
uniprot id: A0A2U4AF96
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

9739:ZP4
gene id: 9739:ZP4
uniprot id: A0A2U3V3U9
uniprot id: A0A2U4BDV1
uniprot id: A0A2U4BDZ1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPB subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Zona pellucida

9739:CACNG5
gene id: 9739:CACNG5
uniprot id: A0A6J3QLG7
names: Similarity
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.

9739:TCEANC2
gene id: 9739:TCEANC2
uniprot id: A0A2U4BJA3
uniprot id: A0A2U4BJP7
names: Subcellular Location Annotation
messages: Nucleus

9739:FAT2
gene id: 9739:FAT2
uniprot id: A0A2U4AH71
uniprot id: A0A2U4AHN8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:GPT
gene id: 9739:GPT
uniprot id: A0A6J3Q9U1
uniprot id: A0A6J3Q9U6
uniprot id: A0A6J3Q9Z5
uniprot id: A0A6J3QA01
uniprot id: A0A6J3QAE5
uniprot id: A0A6J3QAF0
uniprot id: A0A6J3QAL2
uniprot id: A0A6J3QAL9
uniprot id: A0A6J3QAQ7
uniprot id: A0A6J3QAR2
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

9739:OGFR
gene id: 9739:OGFR
uniprot id: A0A6J3Q005
names: Similarity
messages: Belongs to the opioid growth factor receptor family.

9739:CDKN3
gene id: 9739:CDKN3
uniprot id: A0A6J3QXE4
uniprot id: A0A6J3QYT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family.
messages: May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues.
messages: perinuclear region

9739:TRIP10
gene id: 9739:TRIP10
uniprot id: A0A6J3R6J4
uniprot id: A0A6J3R6P4
names: Subcellular Location Annotation
messages: cytoskeleton

9739:LOC101321824
gene id: 9739:LOC101321824
uniprot id: A0A2U4C3L8
names: Subcellular Location Annotation
messages: Membrane

9739:ARMT1
gene id: 9739:ARMT1
uniprot id: A0A2U3V4N4
uniprot id: A0A2U4CPL1
names: Domain
names: Function
names: Similarity
messages: Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.
messages: Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism. Has also been shown to have O-methyltransferase activity that methylates glutamate residues of target proteins to form gamma-glutamyl methyl ester residues. Possibly methylates PCNA, suggesting it is involved in the DNA damage response.
messages: Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine.

9739:CSTB
gene id: 9739:CSTB
uniprot id: A0A2U3V192
names: Similarity
messages: Belongs to the cystatin family.

9739:TIMP2
gene id: 9739:TIMP2
uniprot id: A0A6J3QKX7
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

9739:RRP1B
gene id: 9739:RRP1B
uniprot id: A0A2U3V149
uniprot id: A0A6J3RBB8
uniprot id: A0A6J3RBU5
uniprot id: A0A6J3RC30
uniprot id: A0A6J3RDQ8
names: Similarity
messages: Belongs to the RRP1 family.

9739:RIPOR3
gene id: 9739:RIPOR3
uniprot id: A0A6J3Q346
uniprot id: A0A6J3Q3E6
uniprot id: A0A6J3Q3F2
uniprot id: A0A6J3Q3U8
names: Similarity
messages: Belongs to the RIPOR family.

9739:CKAP5
gene id: 9739:CKAP5
uniprot id: A0A2U4CDB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOG/XMAP215 family.
messages: kinetochore

9739:CCR9
gene id: 9739:CCR9
uniprot id: A0A6J3S1A2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9739:LOC101332158
gene id: 9739:LOC101332158
uniprot id: A0A2U3V7H0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL28 family.

9739:LOC117312634
gene id: 9739:LOC117312634
uniprot id: A0A6J3RJ50
names: Subcellular Location Annotation
messages: Membrane

9739:ISL2
gene id: 9739:ISL2
uniprot id: A0A2U4CN35
names: Subcellular Location Annotation
messages: Nucleus

9739:C6H9orf64
gene id: 9739:C6H9orf64
uniprot id: A0A6J3RG82
uniprot id: A0A6J3RGF3
uniprot id: A0A6J3RGS0
names: Function
names: Similarity
messages: Belongs to the QNG1 protein family.
messages: Catalyzes the hydrolysis of queuosine 5'-phosphate, releasing the nucleobase queuine (q). Is required for salvage of queuine from exogenous queuosine (Q) that is imported and then converted to queuosine 5'-phosphate intracellularly.

9739:PBRM1
gene id: 9739:PBRM1
uniprot id: A0A2U4CC39
uniprot id: A0A2U4CC42
uniprot id: A0A2U4CC44
uniprot id: A0A2U4CC45
uniprot id: A0A2U4CC47
uniprot id: A0A2U4CC61
uniprot id: A0A6J3S259
uniprot id: A0A6J3S2A4
uniprot id: A0A6J3S2D7
uniprot id: A0A6J3S2Z5
uniprot id: A0A6J3S3A0
uniprot id: A0A6J3S3B2
names: Subcellular Location Annotation
messages: Nucleus

9739:CASK
gene id: 9739:CASK
uniprot id: A0A2U4C105
uniprot id: A0A2U4C110
uniprot id: A0A2U4C112
uniprot id: A0A2U4C115
uniprot id: A0A2U4C117
uniprot id: A0A2U4C122
uniprot id: A0A2U4C136
uniprot id: A0A2U4C140
uniprot id: A0A2U4C158
uniprot id: A0A2U4C192
uniprot id: A0A2U4C197
uniprot id: A0A6J3QSB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane

9739:LOC117311133
gene id: 9739:LOC117311133
uniprot id: A0A6J3R1K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.
messages: Catalyzes viral DNA integration into the host chromosome, by performing a series of DNA cutting and joining reactions. This enzyme activity takes place after virion entry into a cell and reverse transcription of the RNA genome in dsDNA. The first step in the integration process is 3' processing. This step requires a complex comprising the viral genome, matrix protein and integrase. This complex is called the pre-integration complex (PIC). The integrase protein removes 2 nucleotides from each 3' end of the viral DNA, leaving recessed CA OH's at the 3' ends. In the second step that requires cell division, the PIC enters cell nucleus. In the third step, termed strand transfer, the integrase protein joins the previously processed 3' ends to the 5' ends of strands of target cellular DNA at the site of integration. The last step is viral DNA integration into host chromosome.
messages: Forms the spherical core of the virion that encapsulates the genomic RNA-nucleocapsid complex.
messages: Virion

9739:LOC101336219
gene id: 9739:LOC101336219
uniprot id: A0A6J3RP24
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

9739:HPS3
gene id: 9739:HPS3
uniprot id: A0A2U4B9K2
uniprot id: A0A2U4B9K3
uniprot id: A0A2U4B9K5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the biogenesis of lysosome-related organelles complex-2 (or BLOC2) composed of HPS3, HPS5 and HPS6.
messages: Cytoplasm
messages: Involved in early stages of melanosome biogenesis and maturation.

9739:SLC26A3
gene id: 9739:SLC26A3
uniprot id: A0A2U4BSK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Mediates chloride-bicarbonate exchange with a chloride bicarbonate stoichiometry of 2:1 in the intestinal epithelia. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation.
messages: Membrane

9739:LOC101322849
gene id: 9739:LOC101322849
uniprot id: A0A2U4A8Q2
uniprot id: A0A2U4A8Q6
uniprot id: A0A2U4A8Q7
uniprot id: A0A2U4A8U3
uniprot id: A0A2U4A9E5
names: Function
names: Similarity
messages: Belongs to the TYW1 family.
messages: Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis.

9739:NUS1
gene id: 9739:NUS1
uniprot id: A0A2U4AW51
names: Similarity
messages: Belongs to the UPP synthase family.

9739:AVPR2
gene id: 9739:AVPR2
uniprot id: A0A6J3QU19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
messages: Membrane

9739:CFAP299
gene id: 9739:CFAP299
uniprot id: A0A2U4B557
uniprot id: A0A2U4B570
uniprot id: A0A2U4B5A4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in spermatogenesis.
messages: Nucleus

9739:CLIP1
gene id: 9739:CLIP1
uniprot id: A0A2U4CJU4
uniprot id: A0A2U4CJU5
uniprot id: A0A2U4CJU7
uniprot id: A0A2U4CJV0
uniprot id: A0A2U4CK25
uniprot id: A0A6J3PRY3
names: Subcellular Location Annotation
messages: cytoskeleton

9739:LOC117309402
gene id: 9739:LOC117309402
uniprot id: A0A6J3QL00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR5 subfamily.
messages: Nucleus

9739:LOC117309108
gene id: 9739:LOC117309108
uniprot id: A0A6J3QFY1
names: Similarity
messages: Belongs to the SNURF family.

9739:TCTEX1D4
gene id: 9739:TCTEX1D4
uniprot id: A0A6J3PRC0
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

9739:NTMT1
gene id: 9739:NTMT1
uniprot id: A0A6J3RIW2
uniprot id: A0A6J3RIW6
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

9739:PHAX
gene id: 9739:PHAX
uniprot id: A0A2U3V4L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PHAX family.
messages: Cytoplasm

9739:SNTG2
gene id: 9739:SNTG2
uniprot id: A0A6J3PW70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: cytoskeleton

9739:DENND5B
gene id: 9739:DENND5B
uniprot id: A0A2U4BD77
names: Caution
names: Similarity
messages: Belongs to the RAB6IP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:CALCB
gene id: 9739:CALCB
uniprot id: A0A2U3V925
uniprot id: A0A6J3RT49
names: Similarity
messages: Belongs to the calcitonin family.

9739:CSF3
gene id: 9739:CSF3
uniprot id: A0A6J3QNP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-6 superfamily.
messages: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes.
messages: Monomer.
messages: Secreted

9739:LOC101333391
gene id: 9739:LOC101333391
uniprot id: A0A2U4BMV6
uniprot id: A0A2U4BN23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

9739:CMPK2
gene id: 9739:CMPK2
uniprot id: A0A2U4C0J0
names: Similarity
messages: Belongs to the thymidylate kinase family.

9739:LOC101337946
gene id: 9739:LOC101337946
uniprot id: A0A6J3RMD7
names: Similarity
messages: Belongs to the heat shock protein 70 family.

9739:LOC117311899
gene id: 9739:LOC117311899
uniprot id: A0A6J3R8A6
names: Subcellular Location Annotation
messages: Secreted

9739:LONP2
gene id: 9739:LONP2
uniprot id: A0A2U3UZ60
uniprot id: A0A2U4B4D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta-oxidation through degradation of the self-processed forms of TYSND1.
messages: Belongs to the peptidase S16 family.
messages: Interacts with PEX5. Interacts with TYSND1.
messages: Peroxisome matrix

9739:GNAQ
gene id: 9739:GNAQ
uniprot id: A0A2U4BAF5
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

9739:CRTC1
gene id: 9739:CRTC1
uniprot id: A0A6J3R532
uniprot id: A0A6J3R537
uniprot id: A0A6J3R567
uniprot id: A0A6J3R573
uniprot id: A0A6J3R5Q0
uniprot id: A0A6J3R626
uniprot id: A0A6J3R631
uniprot id: A0A6J3R7S0
uniprot id: A0A6J3R7S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TORC family.
messages: Cytoplasm
messages: Nucleus

9739:LOC101325151
gene id: 9739:LOC101325151
uniprot id: A0A6J3QCJ0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9739:BLOC1S2
gene id: 9739:BLOC1S2
uniprot id: A0A2U3V4X3
names: Similarity
messages: Belongs to the BLOC1S2 family.

9739:LOC101316201
gene id: 9739:LOC101316201
uniprot id: A0A2U3V4T2
names: Similarity
messages: Belongs to the cytochrome P450 family.

9739:SLC13A1
gene id: 9739:SLC13A1
uniprot id: A0A2U4AHE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

9739:VPS13B
gene id: 9739:VPS13B
uniprot id: A0A6J3Q929
uniprot id: A0A6J3Q939
uniprot id: A0A6J3Q9I5
uniprot id: A0A6J3Q9U5
uniprot id: A0A6J3Q9V0
uniprot id: A0A6J3Q9X3
names: Similarity
messages: Belongs to the VPS13 family.

9739:BCOR
gene id: 9739:BCOR
uniprot id: A0A6J3QTP5
uniprot id: A0A6J3QU59
uniprot id: A0A6J3QUC7
uniprot id: A0A6J3QUL9
uniprot id: A0A6J3QUM4
names: Similarity
messages: Belongs to the BCOR family.

9739:DISP3
gene id: 9739:DISP3
uniprot id: A0A6J3RTH5
names: Subcellular Location Annotation
messages: Membrane

9739:SLC25A41
gene id: 9739:SLC25A41
uniprot id: A0A6J3R758
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9739:LOC101318383
gene id: 9739:LOC101318383
uniprot id: A0A6J3QK38
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9739:COPS5
gene id: 9739:COPS5
uniprot id: A0A2U3UYL4
uniprot id: A0A2U4AIR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M67A family. CSN5 subfamily.
messages: synaptic vesicle

9739:FYTTD1
gene id: 9739:FYTTD1
uniprot id: A0A2U3V6M7
uniprot id: A0A2U4AB50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UIF family.
messages: Nucleus speckle
messages: nucleoplasm

9739:LOC117310389
gene id: 9739:LOC117310389
uniprot id: A0A6J3QU93
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9739:GPR137
gene id: 9739:GPR137
uniprot id: A0A2U3V9N9
uniprot id: A0A2U4B122
uniprot id: A0A2U4B123
uniprot id: A0A2U4B124
uniprot id: A0A2U4B153
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

9739:NFKB2
gene id: 9739:NFKB2
uniprot id: A0A6J3Q772
uniprot id: A0A6J3Q780
uniprot id: A0A6J3Q804
uniprot id: A0A6J3Q815
uniprot id: A0A6J3Q820
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9739:ELP5
gene id: 9739:ELP5
uniprot id: A0A6J3QM26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP5 family.
messages: Cytoplasm
messages: Nucleus

9739:SYK
gene id: 9739:SYK
uniprot id: A0A2U4BF57
uniprot id: A0A2U4BF93
uniprot id: A0A2U4BFJ9
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.

9739:DDB2
gene id: 9739:DDB2
uniprot id: A0A2U3V602
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: Nucleus

9739:GPR180
gene id: 9739:GPR180
uniprot id: A0A2U3V089
uniprot id: A0A2U4A6U2
uniprot id: A0A2U4A6U3
uniprot id: A0A2U4A6Y9
names: Subcellular Location Annotation
messages: Membrane

9739:NUP210
gene id: 9739:NUP210
uniprot id: A0A6J3S3I5
uniprot id: A0A6J3S4H4
names: Similarity
messages: Belongs to the NUP210 family.

9739:VAPA
gene id: 9739:VAPA
uniprot id: A0A2U4A5Q0
uniprot id: A0A2U4A5T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:RPS19
gene id: 9739:RPS19
uniprot id: A0A6J3QCI7
uniprot id: A0A6J3QD24
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS19 family.

9739:LOC101330142
gene id: 9739:LOC101330142
uniprot id: A0A6J3R860
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

9739:NFU1
gene id: 9739:NFU1
uniprot id: A0A2U3VA22
uniprot id: A0A2U4BZW8
uniprot id: A0A2U4C019
uniprot id: A0A2U4C052
uniprot id: A0A6J3PW01
uniprot id: A0A6J3PW03
uniprot id: A0A6J3PWL2
names: Similarity
messages: Belongs to the NifU family.

9739:PTBP1
gene id: 9739:PTBP1
uniprot id: A0A6J3R7S2
uniprot id: A0A6J3R7X8
uniprot id: A0A6J3R8C4
uniprot id: A0A6J3RAN6
names: Subcellular Location Annotation
messages: Nucleus

9739:PARD3B
gene id: 9739:PARD3B
uniprot id: A0A2U4BN45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR3 family.
messages: Cell junction
messages: Endomembrane system

9739:LCTL
gene id: 9739:LCTL
uniprot id: A0A6J3QZ08
uniprot id: A0A6J3QZQ0
uniprot id: A0A6J3QZS7
uniprot id: A0A6J3R0U7
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

9739:TCP11L2
gene id: 9739:TCP11L2
uniprot id: A0A2U3ZYQ5
uniprot id: A0A2U3ZYR2
names: Similarity
messages: Belongs to the TCP11 family.

9739:PSMD1
gene id: 9739:PSMD1
uniprot id: A0A2U4ADN5
uniprot id: A0A2U4ADV2
uniprot id: A0A2U4AE54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S1 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

9739:FAM187B
gene id: 9739:FAM187B
uniprot id: A0A6J3QGF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM187 family.
messages: Membrane

9739:IZUMO4
gene id: 9739:IZUMO4
uniprot id: A0A6J3R7D9
uniprot id: A0A6J3R7H4
uniprot id: A0A6J3R7W3
uniprot id: A0A6J3R7W8
uniprot id: A0A6J3R8F3
uniprot id: A0A6J3RA77
names: Similarity
messages: Belongs to the Izumo family.

9739:HMGN4
gene id: 9739:HMGN4
uniprot id: A0A6J3RY99
uniprot id: A0A6J3RYB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

9739:SSBP2
gene id: 9739:SSBP2
uniprot id: A0A6J3R2A4
uniprot id: A0A6J3R2E3
uniprot id: A0A6J3R2R9
uniprot id: A0A6J3R4G1
names: Subcellular Location Annotation
messages: Nucleus

9739:TBCC
gene id: 9739:TBCC
uniprot id: A0A2U3VAI4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCC family.
messages: Cytoplasm
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.

9739:MSTN
gene id: 9739:MSTN
uniprot id: A0A2U3V6N0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts specifically as a negative regulator of skeletal muscle growth.
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked. Interacts with WFIKKN2, leading to inhibit its activity. Interacts with FSTL3.
messages: Secreted

9739:TFIP11
gene id: 9739:TFIP11
uniprot id: A0A6J3PSQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFP11/STIP family.
messages: Identified in the spliceosome C complex. Found in the Intron Large (IL) complex, a post-mRNA release spliceosomal complex containing the excised intron, U2, U5 and U6 snRNPs, and splicing factors. Interacts with TUFT1. Interacts with DHX15; indicative for a recruitment of DHX15 to the IL complex. Interacts with GCFC2.
messages: Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extracellular matrix.
messages: Nucleus

9739:CA13
gene id: 9739:CA13
uniprot id: A0A2U3V4N2
uniprot id: A0A2U4ALR0
uniprot id: A0A6J3Q8W2
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

9739:LOC101329613
gene id: 9739:LOC101329613
uniprot id: A0A6J3QHA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA12 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9739:VPS37B
gene id: 9739:VPS37B
uniprot id: A0A2U4CK07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

9739:ORC2
gene id: 9739:ORC2
uniprot id: A0A2U4BNJ5
uniprot id: A0A2U4BNQ6
uniprot id: A0A6J3RNH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC2 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Component of the origin recognition complex (ORC).
messages: Nucleus

9739:RAB29
gene id: 9739:RAB29
uniprot id: A0A2U3V050
uniprot id: A0A2U3V056
uniprot id: A0A6J3R365
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

9739:KCND2
gene id: 9739:KCND2
uniprot id: A0A2U4B057
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. D (Shal) (TC 1.A.1.2) subfamily. Kv4.2/KCND2 sub-subfamily.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane
messages: dendrite
messages: dendritic spine

9739:HOXD4
gene id: 9739:HOXD4
uniprot id: A0A2U4ACZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

9739:GALNT3
gene id: 9739:GALNT3
uniprot id: A0A2U4AC75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9739:MTX2
gene id: 9739:MTX2
uniprot id: A0A2U4ACX0
uniprot id: A0A2U4AD70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

9739:LOC101323410
gene id: 9739:LOC101323410
uniprot id: A0A6J3R4X4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

9739:ARF4
gene id: 9739:ARF4
uniprot id: A0A2U3V4F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

9739:PTP4A2
gene id: 9739:PTP4A2
uniprot id: A0A2U4BKW0
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

9739:PSMD11
gene id: 9739:PSMD11
uniprot id: A0A2U3UZU0
names: Similarity
messages: Belongs to the proteasome subunit S9 family.

9739:PGAM2
gene id: 9739:PGAM2
uniprot id: A0A2U4BPA1
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

9739:LIX1
gene id: 9739:LIX1
uniprot id: A0A2U4AW69
uniprot id: A0A2U4AW74
names: Similarity
messages: Belongs to the LIX1 family.

9739:BRAF
gene id: 9739:BRAF
uniprot id: A0A2U4C6J2
uniprot id: A0A2U4C6W2
uniprot id: A0A2U4C715
uniprot id: A0A2U4C7B5
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

9739:SPPL2C
gene id: 9739:SPPL2C
uniprot id: A0A2U3V3L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

9739:TOR1A
gene id: 9739:TOR1A
uniprot id: A0A2U4A467
names: Similarity
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.

9739:TLE4
gene id: 9739:TLE4
uniprot id: A0A2U4CGL5
uniprot id: A0A2U4CGL8
uniprot id: A0A2U4CGM2
uniprot id: A0A2U4CGM4
uniprot id: A0A2U4CGN0
uniprot id: A0A2U4CGN1
uniprot id: A0A2U4CGR9
uniprot id: A0A6J3RHL0
uniprot id: A0A6J3RHY1
uniprot id: A0A6J3RJ86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

9739:FOXP3
gene id: 9739:FOXP3
uniprot id: A0A6J3QR51
uniprot id: A0A6J3QRD5
uniprot id: A0A6J3QRW7
uniprot id: A0A6J3QRX1
names: Subcellular Location Annotation
messages: Nucleus

9739:LOC117307727
gene id: 9739:LOC117307727
uniprot id: A0A6J3PUY9
names: Caution
names: Similarity
messages: Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:CRY1
gene id: 9739:CRY1
uniprot id: A0A2U3ZYR9
uniprot id: A0A2U3ZZR4
uniprot id: A0A6J3S515
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 FAD per subunit.

9739:VNN1
gene id: 9739:VNN1
uniprot id: A0A2U3UZ03
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

9739:ITPKC
gene id: 9739:ITPKC
uniprot id: A0A6J3QD53
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

9739:RNF7
gene id: 9739:RNF7
uniprot id: A0A2U3UZN0
uniprot id: A0A2U4B9I7
names: Similarity
messages: Belongs to the RING-box family.

9739:CAP2
gene id: 9739:CAP2
uniprot id: A0A2U4C5S3
uniprot id: A0A6J3RYV7
uniprot id: A0A6J3RYW9
uniprot id: A0A6J3RZS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAP family.
messages: Cell membrane
messages: Membrane

9739:THYN1
gene id: 9739:THYN1
uniprot id: A0A2U4BWN3
uniprot id: A0A2U4BWU0
uniprot id: A0A2U4BWU2
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

9739:ELAVL4
gene id: 9739:ELAVL4
uniprot id: A0A6J3R2H8
uniprot id: A0A6J3R2M1
uniprot id: A0A6J3R2Z8
uniprot id: A0A6J3R328
uniprot id: A0A6J3R3D4
uniprot id: A0A6J3R483
uniprot id: A0A6J3R4A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM elav family.
messages: Cytoplasm
messages: Perikaryon
messages: axon
messages: dendrite
messages: growth cone

9739:PTGDS
gene id: 9739:PTGDS
uniprot id: A0A6J3RKH9
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

9739:AK6
gene id: 9739:AK6
uniprot id: A0A2U3UYD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation.
messages: Cajal body
messages: Monomer and homodimer. Interacts with COIL (via C-terminus).
messages: nucleoplasm

9739:LAMA1
gene id: 9739:LAMA1
uniprot id: A0A2U4A5A9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

9739:GPRIN2
gene id: 9739:GPRIN2
uniprot id: A0A6J3Q7Q4
uniprot id: A0A6J3Q8I9
names: Function
messages: May be involved in neurite outgrowth.

9739:CDK6
gene id: 9739:CDK6
uniprot id: A0A2U4APP7
names: Similarity
messages: Belongs to the protein kinase superfamily.

9739:CACHD1
gene id: 9739:CACHD1
uniprot id: A0A2U4A4A3
uniprot id: A0A6J3S3G5
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

9739:SNX1
gene id: 9739:SNX1
uniprot id: A0A2U3V1I5
uniprot id: A0A2U4CDN0
uniprot id: A0A2U4CDR8
uniprot id: A0A2U4CDU3
uniprot id: A0A6J3QZ42
uniprot id: A0A6J3R0M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: lamellipodium
messages: trans-Golgi network membrane

9739:PNPLA6
gene id: 9739:PNPLA6
uniprot id: A0A6J3R6F3
uniprot id: A0A6J3R6K4
uniprot id: A0A6J3R707
uniprot id: A0A6J3R711
uniprot id: A0A6J3R7E7
uniprot id: A0A6J3R7F3
uniprot id: A0A6J3R980
uniprot id: A0A6J3R986
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:ITIH2
gene id: 9739:ITIH2
uniprot id: A0A6J3QUP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

9739:ZNF592
gene id: 9739:ZNF592
uniprot id: A0A2U4C753
uniprot id: A0A2U4C763
uniprot id: A0A2U4C772
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

9739:CREBL2
gene id: 9739:CREBL2
uniprot id: A0A2U3V7H4
uniprot id: A0A2U4BIN1
uniprot id: A0A2U4BIP0
uniprot id: A0A2U4BIQ1
uniprot id: A0A2U4BIX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Nucleus

9739:GRID2
gene id: 9739:GRID2
uniprot id: A0A6J3RET3
uniprot id: A0A6J3REV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

9739:MIP
gene id: 9739:MIP
uniprot id: A0A2U3UZF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

9739:RFLNB
gene id: 9739:RFLNB
uniprot id: A0A2U4ANJ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Refilin family.
messages: Interacts with FLNA and FLNB.
messages: cytoskeleton

9739:LOC117313953
gene id: 9739:LOC117313953
uniprot id: A0A6J3S395
names: Similarity
messages: Belongs to the TMA7 family.

9739:SUCNR1
gene id: 9739:SUCNR1
uniprot id: A0A2U4B9R6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9739:SLC35E4
gene id: 9739:SLC35E4
uniprot id: A0A2U4CKX7
names: Subcellular Location Annotation
messages: Membrane

9739:LOC109549914
gene id: 9739:LOC109549914
uniprot id: A0A6J3RGX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

9739:PARP8
gene id: 9739:PARP8
uniprot id: A0A2U4AXB9
uniprot id: A0A2U4AXC1
names: Similarity
messages: Belongs to the ARTD/PARP family.

9739:CLDN4
gene id: 9739:CLDN4
uniprot id: A0A2U3UYQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9739:NUP98
gene id: 9739:NUP98
uniprot id: A0A6J3RUI6
uniprot id: A0A6J3RUJ2
uniprot id: A0A6J3RUR4
uniprot id: A0A6J3RUR8
uniprot id: A0A6J3RUS2
uniprot id: A0A6J3RUV5
uniprot id: A0A6J3RUV8
uniprot id: A0A6J3RUW2
uniprot id: A0A6J3RUW3
uniprot id: A0A6J3RUW7
uniprot id: A0A6J3RVA7
uniprot id: A0A6J3RVB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin GLFG family.
messages: Nucleus membrane
messages: nuclear pore complex

9739:LIN9
gene id: 9739:LIN9
uniprot id: A0A2U4A532
names: Similarity
messages: Belongs to the lin-9 family.

9739:DHRS9
gene id: 9739:DHRS9
uniprot id: A0A2U3V3D3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9739:TCTEX1D2
gene id: 9739:TCTEX1D2
uniprot id: A0A2U4ACZ2
uniprot id: A0A2U4ADG2
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

9739:TMC4
gene id: 9739:TMC4
uniprot id: A0A6J3QHP9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:ATP10B
gene id: 9739:ATP10B
uniprot id: A0A2U4C683
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

9739:LOC109552897
gene id: 9739:LOC109552897
uniprot id: A0A6J3S7C8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9739:TSPAN11
gene id: 9739:TSPAN11
uniprot id: A0A6J3S8A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9739:ALOX15
gene id: 9739:ALOX15
uniprot id: A0A6J3QMN1
names: Caution
names: Cofactor
messages: Binds 1 Fe cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:RNFT2
gene id: 9739:RNFT2
uniprot id: A0A6J3PRL7
uniprot id: A0A6J3PRS1
uniprot id: A0A6J3PS67
uniprot id: A0A6J3PSQ9
names: Subcellular Location Annotation
messages: Membrane

9739:ACSM3
gene id: 9739:ACSM3
uniprot id: A0A2U3V566
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

9739:SLC46A2
gene id: 9739:SLC46A2
uniprot id: A0A6J3RI50
names: Subcellular Location Annotation
messages: Membrane

9739:PIWIL2
gene id: 9739:PIWIL2
uniprot id: A0A2U4BF22
uniprot id: A0A2U4BFE5
names: Similarity
messages: Belongs to the argonaute family.

9739:LOC101336063
gene id: 9739:LOC101336063
uniprot id: A0A6J3RCM0
names: Function
names: Subcellular Location Annotation
messages: May play a role during embryogenesis.
messages: kinetochore

9739:LPCAT4
gene id: 9739:LPCAT4
uniprot id: A0A6J3QY71
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

9739:LOXL2
gene id: 9739:LOXL2
uniprot id: A0A6J3RFQ3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

9739:ESCO2
gene id: 9739:ESCO2
uniprot id: A0A2U3V2W1
names: Subcellular Location Annotation
messages: Nucleus

9739:NPL
gene id: 9739:NPL
uniprot id: A0A2U4CRS0
uniprot id: A0A2U4CS25
uniprot id: A0A6J3R4I3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family. NanA subfamily.
messages: Cytoplasm
messages: Homotetramer.

9739:PADI2
gene id: 9739:PADI2
uniprot id: A0A6J3Q8D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Catalyzes the deimination of arginine residues of proteins.
messages: Cytoplasm

9739:CPNE2
gene id: 9739:CPNE2
uniprot id: A0A6J3QHB1
names: Similarity
messages: Belongs to the copine family.

9739:DUXA
gene id: 9739:DUXA
uniprot id: A0A2U4ATN3
names: Subcellular Location Annotation
messages: Nucleus

9739:MFSD5
gene id: 9739:MFSD5
uniprot id: A0A2U4CBJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Cell membrane
messages: Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.
messages: Membrane

9739:RMND1
gene id: 9739:RMND1
uniprot id: A0A2U4CP98
uniprot id: A0A6J3S9U1
uniprot id: A0A6J3SAY6
names: Similarity
messages: Belongs to the RMD1/sif2 family.

9739:EPHA6
gene id: 9739:EPHA6
uniprot id: A0A2U4A9Y9
names: Subcellular Location Annotation
messages: Membrane

9739:LOC101321628
gene id: 9739:LOC101321628
uniprot id: A0A2U4AQ98
uniprot id: A0A2U4AQA0
uniprot id: A0A2U4AQA6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9739:LOC101317864
gene id: 9739:LOC101317864
uniprot id: A0A6J3PY79
names: Similarity
messages: Belongs to the replication factor A protein 2 family.

9739:ACADM
gene id: 9739:ACADM
uniprot id: A0A2U4A366
uniprot id: A0A2U4A403
uniprot id: A0A6J3S296
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Mitochondrion matrix

9739:LOC101336616
gene id: 9739:LOC101336616
uniprot id: A0A6J3RHW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecE/SEC61-gamma family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:TWF1
gene id: 9739:TWF1
uniprot id: A0A2U4BAA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

9739:LOC117310227
gene id: 9739:LOC117310227
uniprot id: A0A6J3QS90
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

9739:RGS5
gene id: 9739:RGS5
uniprot id: A0A2U3V8H5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha.

9739:SAG
gene id: 9739:SAG
uniprot id: A0A2U3V8Q0
names: Similarity
messages: Belongs to the arrestin family.

9739:RPL14
gene id: 9739:RPL14
uniprot id: A0A2U3V8C2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

9739:EPHA2
gene id: 9739:EPHA2
uniprot id: A0A6J3Q860
uniprot id: A0A6J3Q864
uniprot id: A0A6J3Q872
uniprot id: A0A6J3Q8Y7
names: Subcellular Location Annotation
messages: Membrane

9739:CYFIP1
gene id: 9739:CYFIP1
uniprot id: A0A2U4B2B8
names: Similarity
messages: Belongs to the CYFIP family.

9739:CWF19L1
gene id: 9739:CWF19L1
uniprot id: A0A2U3V4X9
uniprot id: A0A2U4BQ94
names: Similarity
messages: Belongs to the CWF19 family.

9739:TBL1XR1
gene id: 9739:TBL1XR1
uniprot id: A0A2U4C8F9
uniprot id: A0A2U4C8G5
names: Similarity
messages: Belongs to the WD repeat EBI family.

9739:LOC101321104
gene id: 9739:LOC101321104
uniprot id: A0A2U4C2E2
names: Similarity
messages: Belongs to the cytochrome P450 family.

9739:KAT7
gene id: 9739:KAT7
uniprot id: A0A2U3V4V7
uniprot id: A0A2U3V584
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

9739:LOC117313557
gene id: 9739:LOC117313557
uniprot id: A0A6J3RVU3
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

9739:CTU2
gene id: 9739:CTU2
uniprot id: A0A6J3QIT9
uniprot id: A0A6J3QJC8
uniprot id: A0A6J3QJF4
uniprot id: A0A6J3QJW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTU2/NCS2 family.
messages: Component of a complex at least composed of URM1, CTU2/NCS2 and CTU1/ATPBD3.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with CTU1/ATPBD3 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

9739:NSFL1C
gene id: 9739:NSFL1C
uniprot id: A0A2U3V8B0
uniprot id: A0A2U3V8Q1
uniprot id: A0A2U4CLU1
uniprot id: A0A2U4CLV0
names: Subcellular Location Annotation
names: Subunit
messages: Golgi stack
messages: Part of a ternary complex containing STX5A, NSFL1C and VCP. NSFL1C forms a homotrimer that binds to one end of a VCP homohexamer. The complex binds to membranes enriched in phosphatidylethanolamine-containing lipids and promotes Golgi membrane fusion. Interaction with VCIP135 leads to dissociation of the complex via ATP hydrolysis by VCP. Binds ubiquitin and mono-ubiquitinated proteins via its N-terminal UBA-like domain when bound to VCP.

9739:LOC101330221
gene id: 9739:LOC101330221
uniprot id: A0A2U4BFF3
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

9739:LOC117314326
gene id: 9739:LOC117314326
uniprot id: A0A6J3S8C2
names: Subcellular Location Annotation
messages: Nucleus

9739:LOC109552138
gene id: 9739:LOC109552138
uniprot id: A0A2U4CC46
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space
messages: Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

9739:CASTOR2
gene id: 9739:CASTOR2
uniprot id: A0A6J3Q1N4
names: Similarity
messages: Belongs to the GATS family.

9739:KIF13A
gene id: 9739:KIF13A
uniprot id: A0A2U4C539
uniprot id: A0A2U4C559
uniprot id: A0A6J3RYT3
uniprot id: A0A6J3RYW2
uniprot id: A0A6J3RYX5
uniprot id: A0A6J3RZ29
uniprot id: A0A6J3RZ34
uniprot id: A0A6J3RZS4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9739:GPR15
gene id: 9739:GPR15
uniprot id: A0A2U3V4B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9739:SLC6A3
gene id: 9739:SLC6A3
uniprot id: A0A6J3R3P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A3 subfamily.
messages: Cell membrane
messages: Membrane
messages: axon
messages: neuron projection

9739:LOC101328772
gene id: 9739:LOC101328772
uniprot id: A0A2U4AG83
names: Similarity
messages: Belongs to the serpin family.

9739:QKI
gene id: 9739:QKI
uniprot id: A0A2U4CNZ5
uniprot id: A0A2U4CNZ8
uniprot id: A0A2U4CP02
uniprot id: A0A2U4CPA3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer. Does not require RNA to homodimerize. Able to heterodimerize with BICC1.
messages: Nucleus
messages: RNA-binding protein that plays a central role in myelinization. Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B which promotes oligodendrocyte differentiation. Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor.

9739:FAM13A
gene id: 9739:FAM13A
uniprot id: A0A2U4ALY5
uniprot id: A0A2U4AM11
names: Similarity
messages: Belongs to the FAM13 family.

9739:LOC109551996
gene id: 9739:LOC109551996
uniprot id: A0A6J3RZ88
names: Subcellular Location Annotation
messages: Cytoplasm

9739:PDGFRL
gene id: 9739:PDGFRL
uniprot id: A0A6J3QRH8
names: Subunit
messages: Forms a complex composed of PDGFRL, TNK2 and GRB2.

9739:FZD8
gene id: 9739:FZD8
uniprot id: A0A2U4B6Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

9739:CCNA2
gene id: 9739:CCNA2
uniprot id: A0A2U4AR61
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

9739:LBP
gene id: 9739:LBP
uniprot id: A0A6J3Q236
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide.
messages: Secreted
messages: When bound to LPS, interacts (via C-terminus) with soluble and membrane-bound CD14.

9739:MAN1C1
gene id: 9739:MAN1C1
uniprot id: A0A6J3Q2S4
uniprot id: A0A6J3Q3H3
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

9739:RPL32
gene id: 9739:RPL32
uniprot id: A0A2U4C435
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

9739:FSIP1
gene id: 9739:FSIP1
uniprot id: A0A6J3QYR3
names: Similarity
messages: Belongs to the FSIP1 family.

9739:AGA
gene id: 9739:AGA
uniprot id: A0A2U3V6Z6
uniprot id: A0A2U4A7S2
uniprot id: A0A2U4A7W5
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

9739:LOC117310103
gene id: 9739:LOC117310103
uniprot id: A0A6J3QRT6
names: Similarity
messages: Belongs to the SERF family.

9739:TIGD2
gene id: 9739:TIGD2
uniprot id: A0A2U4AMC2
names: Subcellular Location Annotation
messages: Nucleus

9739:DAPK3
gene id: 9739:DAPK3
uniprot id: A0A6J3R7J8
names: Similarity
messages: Belongs to the protein kinase superfamily.

9739:TAC1
gene id: 9739:TAC1
uniprot id: A0A2U3V1Z5
uniprot id: A0A2U3V242
uniprot id: A0A2U3V259
uniprot id: A0A2U3V2G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted
messages: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.

9739:LOC101325051
gene id: 9739:LOC101325051
uniprot id: A0A2U4CMM0
uniprot id: A0A2U4CMM9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9739:NKAIN4
gene id: 9739:NKAIN4
uniprot id: A0A6J3Q4A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

9739:MVB12B
gene id: 9739:MVB12B
uniprot id: A0A6J3RIM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MVB12 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

9739:MRPL28
gene id: 9739:MRPL28
uniprot id: A0A6J3Q2L7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

9739:ENTPD2
gene id: 9739:ENTPD2
uniprot id: A0A6J3RK21
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

9739:CCDC85B
gene id: 9739:CCDC85B
uniprot id: A0A2U3UZL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC85 family.
messages: adherens junction

9739:DKC1
gene id: 9739:DKC1
uniprot id: A0A2U4BIG9
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

9739:BCL9L
gene id: 9739:BCL9L
uniprot id: A0A6J3RTM5
uniprot id: A0A6J3RTM9
uniprot id: A0A6J3RTS0
uniprot id: A0A6J3RU06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCL9 family.
messages: Nucleus

9739:LLPH
gene id: 9739:LLPH
uniprot id: A0A2U3V6C7
names: Similarity
messages: Belongs to the learning-associated protein family.

9739:EIF4E
gene id: 9739:EIF4E
uniprot id: A0A2U4AM14
uniprot id: A0A2U4AM17
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

9739:SCNM1
gene id: 9739:SCNM1
uniprot id: A0A6J3RLX1
names: Subcellular Location Annotation
messages: Nucleus speckle
messages: nucleoplasm

9739:SLC44A2
gene id: 9739:SLC44A2
uniprot id: A0A6J3R5Z1
uniprot id: A0A6J3R634
uniprot id: A0A6J3R6L3
uniprot id: A0A6J3R6Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

9739:GSPT2
gene id: 9739:GSPT2
uniprot id: A0A2U3V9U7
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

9739:ITGAL
gene id: 9739:ITGAL
uniprot id: A0A6J3Q0J2
uniprot id: A0A6J3Q0L3
uniprot id: A0A6J3Q157
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9739:CHRNB4
gene id: 9739:CHRNB4
uniprot id: A0A2U3V8I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9739:TRUB2
gene id: 9739:TRUB2
uniprot id: A0A6J3RIN7
uniprot id: A0A6J3RIY4
uniprot id: A0A6J3RIZ3
uniprot id: A0A6J3RJQ5
uniprot id: A0A6J3RKN6
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

9739:GET1
gene id: 9739:GET1
uniprot id: A0A2U3V3T5
uniprot id: A0A2U4AB05
uniprot id: A0A6J3RB45
uniprot id: A0A6J3RBL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WRB/GET1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:EFNA1
gene id: 9739:EFNA1
uniprot id: A0A2U3V863
uniprot id: A0A2U4B878
uniprot id: A0A2U4B8D5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:DNAJC10
gene id: 9739:DNAJC10
uniprot id: A0A2U4B229
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins.
messages: Endoplasmic reticulum lumen

9739:STPG1
gene id: 9739:STPG1
uniprot id: A0A2U4BLH3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9739:TDGF1
gene id: 9739:TDGF1
uniprot id: A0A2U4CA01
names: Caution
names: Similarity
messages: Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:KIF9
gene id: 9739:KIF9
uniprot id: A0A6J3S1D5
uniprot id: A0A6J3S1E2
uniprot id: A0A6J3S1E7
uniprot id: A0A6J3S1G0
uniprot id: A0A6J3S1G4
uniprot id: A0A6J3S1J0
uniprot id: A0A6J3S1J7
uniprot id: A0A6J3S220
uniprot id: A0A6J3S224
uniprot id: A0A6J3S231
uniprot id: A0A6J3S2H6
uniprot id: A0A6J3S2H7
uniprot id: A0A6J3S2I2
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:KCNK15
gene id: 9739:KCNK15
uniprot id: A0A2U4C1I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

9739:ARVCF
gene id: 9739:ARVCF
uniprot id: A0A6J3PT41
uniprot id: A0A6J3PTB2
uniprot id: A0A6J3PTP9
uniprot id: A0A6J3PTR8
uniprot id: A0A6J3PU94
uniprot id: A0A6J3PU98
names: Similarity
messages: Belongs to the beta-catenin family.

9739:PICK1
gene id: 9739:PICK1
uniprot id: A0A6J3S4T1
uniprot id: A0A6J3S4Y4
uniprot id: A0A6J3S540
uniprot id: A0A6J3S5Y9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competitive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.
messages: cytoskeleton
messages: perinuclear region
messages: synaptosome

9739:EFHB
gene id: 9739:EFHB
uniprot id: A0A2U4B8Z1
names: Subcellular Location Annotation
messages: cilium axoneme

9739:NAPB
gene id: 9739:NAPB
uniprot id: A0A2U4AQ81
uniprot id: A0A2U4AQ87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

9739:DMRTC2
gene id: 9739:DMRTC2
uniprot id: A0A6J3QCF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

9739:LSM14B
gene id: 9739:LSM14B
uniprot id: A0A6J3PY10
uniprot id: A0A6J3PY22
uniprot id: A0A6J3PY95
uniprot id: A0A6J3PYJ1
names: Similarity
messages: Belongs to the LSM14 family.

9739:LOC101328728
gene id: 9739:LOC101328728
uniprot id: A0A2U4B054
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Secreted

9739:STOML1
gene id: 9739:STOML1
uniprot id: A0A2U4CHW8
uniprot id: A0A2U4CHX5
uniprot id: A0A2U4CI03
uniprot id: A0A6J3R044
uniprot id: A0A6J3R171
names: Similarity
messages: Belongs to the band 7/mec-2 family.

9739:RRS1
gene id: 9739:RRS1
uniprot id: A0A2U4AIT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRS1 family.
messages: Involved in ribosomal large subunit assembly.
messages: Nucleus

9739:IP6K1
gene id: 9739:IP6K1
uniprot id: A0A2U4B246
uniprot id: A0A2U4B2D9
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

9739:IFT43
gene id: 9739:IFT43
uniprot id: A0A2U4A5D7
uniprot id: A0A2U4A695
uniprot id: A0A6J3QWZ7
names: Similarity
messages: Belongs to the IFT43 family.

9739:ADAMTS2
gene id: 9739:ADAMTS2
uniprot id: A0A6J3R4E5
uniprot id: A0A6J3R4U7
uniprot id: A0A6J3R6L6
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9739:SLC41A2
gene id: 9739:SLC41A2
uniprot id: A0A2U4A0V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

9739:NPEPPS
gene id: 9739:NPEPPS
uniprot id: A0A6J3QP24
uniprot id: A0A6J3QP57
uniprot id: A0A6J3QPW9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Membrane

9739:SLC17A9
gene id: 9739:SLC17A9
uniprot id: A0A6J3Q0N0
uniprot id: A0A6J3Q0W3
uniprot id: A0A6J3Q180
names: Subcellular Location Annotation
messages: Membrane

9739:FAM221B
gene id: 9739:FAM221B
uniprot id: A0A2U4CGP7
names: Similarity
messages: Belongs to the FAM221 family.

9739:LOC117314473
gene id: 9739:LOC117314473
uniprot id: A0A6J3S9G0
names: Similarity
messages: Belongs to the nucleoplasmin family.

9739:CLCC1
gene id: 9739:CLCC1
uniprot id: A0A2U4A3C4
uniprot id: A0A6J3RVA9
uniprot id: A0A6J3RVG6
uniprot id: A0A6J3RVX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel MCLC family.
messages: Membrane

9739:PPP2R5B
gene id: 9739:PPP2R5B
uniprot id: A0A6J3RQB8
uniprot id: A0A6J3RQN1
uniprot id: A0A6J3RQR8
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

9739:LOC117314322
gene id: 9739:LOC117314322
uniprot id: A0A6J3S9T3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9739:RNF114
gene id: 9739:RNF114
uniprot id: A0A2U3V7P2
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with XAF1, the interaction increases XAF1 stability and proapoptotic effects, and may regulate IFN signaling.
messages: Nucleus

9739:LOC101336124
gene id: 9739:LOC101336124
uniprot id: A0A2U3VA06
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:LOC101317850
gene id: 9739:LOC101317850
uniprot id: A0A6J3S7J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

9739:CPT1A
gene id: 9739:CPT1A
uniprot id: A0A6J3RS56
uniprot id: A0A6J3RS89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

9739:FAM174B
gene id: 9739:FAM174B
uniprot id: A0A2U4C6V3
uniprot id: A0A6J3R1S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM174 family.
messages: Membrane

9739:APOA5
gene id: 9739:APOA5
uniprot id: A0A2U4BWL5
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

9739:TPD52L2
gene id: 9739:TPD52L2
uniprot id: A0A2U3V3B7
uniprot id: A0A2U3V3H3
names: Similarity
messages: Belongs to the TPD52 family.

9739:JPH2
gene id: 9739:JPH2
uniprot id: A0A6J3Q3W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

9739:LOC117307512
gene id: 9739:LOC117307512
uniprot id: A0A2U4C2W5
uniprot id: A0A2U4C2Y0
uniprot id: A0A2U4C2Y3
uniprot id: A0A2U4C306
uniprot id: A0A2U4C331
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.

9739:SLCO2B1
gene id: 9739:SLCO2B1
uniprot id: A0A6J3RU50
uniprot id: A0A6J3RUI8
uniprot id: A0A6J3RUK8
uniprot id: A0A6J3RUW0
uniprot id: A0A6J3RUW5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:LOC101324532
gene id: 9739:LOC101324532
uniprot id: A0A2U3V444
uniprot id: A0A2U4C0C5
uniprot id: A0A2U4C0G9
uniprot id: A0A6J3PWV6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Presynaptic cell membrane

9739:CDIP1
gene id: 9739:CDIP1
uniprot id: A0A2U3UYU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

9739:FADS2
gene id: 9739:FADS2
uniprot id: A0A6J3RQ21
uniprot id: A0A6J3RQR0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

9739:KCNAB3
gene id: 9739:KCNAB3
uniprot id: A0A6J3QQ33
uniprot id: A0A6J3QQ79
uniprot id: A0A6J3QQU1
uniprot id: A0A6J3QQX7
uniprot id: A0A6J3QRC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cytoplasm

9739:KIF2A
gene id: 9739:KIF2A
uniprot id: A0A2U4AX50
uniprot id: A0A2U4AX67
uniprot id: A0A2U4AX87
uniprot id: A0A2U4AXM5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9739:LOC117312132
gene id: 9739:LOC117312132
uniprot id: A0A6J3R960
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

9739:PCNA
gene id: 9739:PCNA
uniprot id: A0A6J3PZG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PCNA family.
messages: Nucleus
messages: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

9739:SUMO3
gene id: 9739:SUMO3
uniprot id: A0A2U4AB77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

9739:LOC101317071
gene id: 9739:LOC101317071
uniprot id: A0A6J3RNF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP14 family.
messages: nucleolus

9739:LOC101330165
gene id: 9739:LOC101330165
uniprot id: A0A2U3V8D9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

9739:HSF4
gene id: 9739:HSF4
uniprot id: A0A6J3QHB2
uniprot id: A0A6J3QI09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

9739:HSD17B7
gene id: 9739:HSD17B7
uniprot id: A0A6J3RCR4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily.

9739:LOC117310104
gene id: 9739:LOC117310104
uniprot id: A0A6J3QSE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.
messages: Catalyzes viral DNA integration into the host chromosome, by performing a series of DNA cutting and joining reactions. This enzyme activity takes place after virion entry into a cell and reverse transcription of the RNA genome in dsDNA. The first step in the integration process is 3' processing. This step requires a complex comprising the viral genome, matrix protein and integrase. This complex is called the pre-integration complex (PIC). The integrase protein removes 2 nucleotides from each 3' end of the viral DNA, leaving recessed CA OH's at the 3' ends. In the second step that requires cell division, the PIC enters cell nucleus. In the third step, termed strand transfer, the integrase protein joins the previously processed 3' ends to the 5' ends of strands of target cellular DNA at the site of integration. The last step is viral DNA integration into host chromosome.
messages: Forms the spherical core of the virion that encapsulates the genomic RNA-nucleocapsid complex.
messages: Virion

9739:IER5L
gene id: 9739:IER5L
uniprot id: A0A2U4CHH6
names: Similarity
messages: Belongs to the IER family.

9739:CASR
gene id: 9739:CASR
uniprot id: A0A2U4AD46
uniprot id: A0A2U4ADB3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9739:TMEM19
gene id: 9739:TMEM19
uniprot id: A0A2U3V842
uniprot id: A0A2U4CRS4
uniprot id: A0A2U4CRT1
uniprot id: A0A2U4CS40
uniprot id: A0A2U4CS43
uniprot id: A0A6J3S6Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

9739:TMED1
gene id: 9739:TMED1
uniprot id: A0A6J3R6K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

9739:LOC101331276
gene id: 9739:LOC101331276
uniprot id: A0A6J3S8B5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

9739:PPP4C
gene id: 9739:PPP4C
uniprot id: A0A6J3Q2E8
uniprot id: A0A6J3Q2Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family.
messages: Cytoplasm

9739:C3H19orf53
gene id: 9739:C3H19orf53
uniprot id: A0A2U3V8K7
names: Function
names: Similarity
messages: Belongs to the UPF0390 family.
messages: May have a potential role in hypercalcemia of malignancy.

9739:DNM2
gene id: 9739:DNM2
uniprot id: A0A6J3R5Y0
uniprot id: A0A6J3R615
uniprot id: A0A6J3R620
uniprot id: A0A6J3R6J7
uniprot id: A0A6J3R6K0
uniprot id: A0A6J3R6W7
uniprot id: A0A6J3R6X1
uniprot id: A0A6J3R8N9
uniprot id: A0A6J3R8P4
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

9739:ZDHHC20
gene id: 9739:ZDHHC20
uniprot id: A0A2U4BGW7
uniprot id: A0A2U4BGW8
uniprot id: A0A2U4BGW9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9739:WDR55
gene id: 9739:WDR55
uniprot id: A0A2U3V5K8
uniprot id: A0A6J3R3L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR55 family.
messages: Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis.
messages: nucleolus

9739:IMPG2
gene id: 9739:IMPG2
uniprot id: A0A6J3RA65
uniprot id: A0A6J3RB92
names: Subcellular Location Annotation
messages: interphotoreceptor matrix

9739:ZUP1
gene id: 9739:ZUP1
uniprot id: A0A2U4AW47
uniprot id: A0A2U4AW72
uniprot id: A0A6J3S9A1
names: Similarity
names: Subunit
messages: Belongs to the peptidase C78 family. ZUFSP subfamily.
messages: Interacts with RPA1 and RPA2.

9739:NECAP1
gene id: 9739:NECAP1
uniprot id: A0A2U3V3P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

9739:FGF10
gene id: 9739:FGF10
uniprot id: A0A6J3R412
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9739:TIMP3
gene id: 9739:TIMP3
uniprot id: A0A2U3V369
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

9739:RPS3
gene id: 9739:RPS3
uniprot id: A0A2U3UZY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: spindle

9739:ALDH1A1
gene id: 9739:ALDH1A1
uniprot id: A0A2U4BAL8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

9739:LOC101317129
gene id: 9739:LOC101317129
uniprot id: A0A6J3RK39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIIc family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits, encoded in the mitochondrial DNA, and 11 supernumerary subunits, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

9739:ZNF215
gene id: 9739:ZNF215
uniprot id: A0A2U4CE55
names: Subcellular Location Annotation
messages: Nucleus

9739:GNB4
gene id: 9739:GNB4
uniprot id: A0A2U4C8D2
uniprot id: A0A6J3RAA6
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

9739:LOC109552232
gene id: 9739:LOC109552232
uniprot id: A0A2U4CE48
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9739:EPS8
gene id: 9739:EPS8
uniprot id: A0A6J3S8T6
names: Similarity
messages: Belongs to the EPS8 family.

9739:MTM1
gene id: 9739:MTM1
uniprot id: A0A2U4BNQ3
uniprot id: A0A2U4BNR0
uniprot id: A0A2U4BNW3
uniprot id: A0A6J3QT27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

9739:LOC101326734
gene id: 9739:LOC101326734
uniprot id: A0A2U4CJD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

9739:LRP8
gene id: 9739:LRP8
uniprot id: A0A6J3S5J6
uniprot id: A0A6J3S5K1
uniprot id: A0A6J3S5R3
uniprot id: A0A6J3S5T3
uniprot id: A0A6J3S5X7
uniprot id: A0A6J3S5Z0
uniprot id: A0A6J3S626
uniprot id: A0A6J3S674
uniprot id: A0A6J3S6X8
uniprot id: A0A6J3S6Y9
uniprot id: A0A6J3S6Z4
uniprot id: A0A6J3S772
uniprot id: A0A6J3S785
uniprot id: A0A6J3S7A7
uniprot id: A0A6J3S7B7
uniprot id: A0A6J3S7C2
uniprot id: A0A6J3S7D2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:LOC117311679
gene id: 9739:LOC117311679
uniprot id: A0A6J3R4A0
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

9739:CDK5R2
gene id: 9739:CDK5R2
uniprot id: A0A6J3RND7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin-dependent kinase 5 activator family.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit and a regulatory subunit.
messages: Membrane

9739:LOC117313766
gene id: 9739:LOC117313766
uniprot id: A0A6J3RYJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Secreted

9739:TIMM10
gene id: 9739:TIMM10
uniprot id: A0A2U3V1P1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

9739:GIP
gene id: 9739:GIP
uniprot id: A0A2U3V848
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion.
messages: Secreted

9739:SGTA
gene id: 9739:SGTA
uniprot id: A0A6J3R7I5
uniprot id: A0A6J3R7L8
names: Similarity
messages: Belongs to the SGT family.

9739:LOC101339378
gene id: 9739:LOC101339378
uniprot id: A0A6J3S4D4
uniprot id: A0A6J3S4M0
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

9739:BTBD10
gene id: 9739:BTBD10
uniprot id: A0A2U4CDM4
uniprot id: A0A2U4CDM8
uniprot id: A0A2U4CDN3
uniprot id: A0A2U4CDN7
names: Subcellular Location Annotation
messages: Cytoplasm

9739:LOC101334845
gene id: 9739:LOC101334845
uniprot id: A0A2U3V822
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CybS family.
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

9739:COL4A1
gene id: 9739:COL4A1
uniprot id: A0A6J3Q9Y2
uniprot id: A0A6J3QAQ9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

9739:LOC101336494
gene id: 9739:LOC101336494
uniprot id: A0A6J3REA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

9739:MED14
gene id: 9739:MED14
uniprot id: A0A2U4C0X2
uniprot id: A0A2U4C0Z3
uniprot id: A0A2U4C111
uniprot id: A0A2U4C149
uniprot id: A0A6J3QUU8
uniprot id: A0A6J3QVK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 14 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

9739:RPS24
gene id: 9739:RPS24
uniprot id: A0A2U3V8P7
uniprot id: A0A2U3V8Q3
uniprot id: A0A2U3V929
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

9739:CRHR2
gene id: 9739:CRHR2
uniprot id: A0A6J3RWX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Membrane

9739:NOP2
gene id: 9739:NOP2
uniprot id: A0A6J3S7V9
uniprot id: A0A6J3S9B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: nucleolus

9739:ETV3L
gene id: 9739:ETV3L
uniprot id: A0A6J3QPK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9739:HAX1
gene id: 9739:HAX1
uniprot id: A0A2U3V9Z0
uniprot id: A0A2U4A243
names: Function
names: Similarity
messages: Belongs to the HAX1 family.
messages: Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools.

9739:YARS2
gene id: 9739:YARS2
uniprot id: A0A2U4BCS3
uniprot id: A0A2U4BCS5
uniprot id: A0A2U4BCT2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9739:OVOL2
gene id: 9739:OVOL2
uniprot id: A0A2U3UZ94
uniprot id: A0A2U4AQ44
uniprot id: A0A2U4AQ50
names: Subcellular Location Annotation
messages: Nucleus

9739:F3
gene id: 9739:F3
uniprot id: A0A2U3V420
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tissue factor family.
messages: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
messages: Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII.
messages: Membrane

9739:PYGL
gene id: 9739:PYGL
uniprot id: A0A2U4AEQ2
uniprot id: A0A2U4AEQ4
uniprot id: A0A2U4AEW5
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

9739:CADM3
gene id: 9739:CADM3
uniprot id: A0A6J3RDR7
uniprot id: A0A6J3RDT6
uniprot id: A0A6J3RFB1
names: Similarity
messages: Belongs to the nectin family.

9739:HOXC8
gene id: 9739:HOXC8
uniprot id: A0A6J3S6I9
names: Subcellular Location Annotation
messages: Nucleus

9739:ANO8
gene id: 9739:ANO8
uniprot id: A0A6J3R4R1
uniprot id: A0A6J3R4W6
uniprot id: A0A6J3R5C8
uniprot id: A0A6J3R5M5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9739:NT5C2
gene id: 9739:NT5C2
uniprot id: A0A2U4BQI3
uniprot id: A0A2U4BQI4
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

9739:ACVRL1
gene id: 9739:ACVRL1
uniprot id: A0A6J3S7T0
uniprot id: A0A6J3S847
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

9739:CDH18
gene id: 9739:CDH18
uniprot id: A0A2U4CMB8
uniprot id: A0A6J3R2E7
uniprot id: A0A6J3R3S0
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

9739:LOC117311162
gene id: 9739:LOC117311162
uniprot id: A0A6J3R0W1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:TAMM41
gene id: 9739:TAMM41
uniprot id: A0A2U4C3R9
uniprot id: A0A2U4C3S5
uniprot id: A0A6J3S499
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAM41 family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Mitochondrion inner membrane

9739:LOC117314458
gene id: 9739:LOC117314458
uniprot id: A0A6J3S8K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.
messages: Catalyzes viral DNA integration into the host chromosome, by performing a series of DNA cutting and joining reactions. This enzyme activity takes place after virion entry into a cell and reverse transcription of the RNA genome in dsDNA. The first step in the integration process is 3' processing. This step requires a complex comprising the viral genome, matrix protein and integrase. This complex is called the pre-integration complex (PIC). The integrase protein removes 2 nucleotides from each 3' end of the viral DNA, leaving recessed CA OH's at the 3' ends. In the second step that requires cell division, the PIC enters cell nucleus. In the third step, termed strand transfer, the integrase protein joins the previously processed 3' ends to the 5' ends of strands of target cellular DNA at the site of integration. The last step is viral DNA integration into host chromosome.
messages: Forms the spherical core of the virion that encapsulates the genomic RNA-nucleocapsid complex.
messages: Virion

9739:DDX47
gene id: 9739:DDX47
uniprot id: A0A2U4BIP2
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.

9739:OPRK1
gene id: 9739:OPRK1
uniprot id: A0A2U4AJ42
uniprot id: A0A2U4AJP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain. Plays a role in mediating reduced physical activity upon treatment with synthetic opioids. Plays a role in the regulation of salivation in response to synthetic opioids. May play a role in arousal and regulation of autonomic and neuroendocrine functions.
messages: Interacts with NHERF1. Interacts with GABARAPL1.
messages: Membrane

9739:SIAH2
gene id: 9739:SIAH2
uniprot id: A0A2U4B9L8
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

9739:TMEM59L
gene id: 9739:TMEM59L
uniprot id: A0A6J3R552
uniprot id: A0A6J3R5N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM59 family.
messages: Golgi apparatus membrane
messages: Membrane

9739:VAMP2
gene id: 9739:VAMP2
uniprot id: A0A6J3QPM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

9739:ALDH3B1
gene id: 9739:ALDH3B1
uniprot id: A0A6J3RR68
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

9739:CPM
gene id: 9739:CPM
uniprot id: A0A2U4CR66
names: Similarity
messages: Belongs to the peptidase M14 family.

9739:LOC101319900
gene id: 9739:LOC101319900
uniprot id: A0A6J3RKP6
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

9739:CPEB4
gene id: 9739:CPEB4
uniprot id: A0A2U3V1W1
uniprot id: A0A2U3V271
uniprot id: A0A2U4C8B9
names: Similarity
messages: Belongs to the RRM CPEB family.

9739:SEMA6B
gene id: 9739:SEMA6B
uniprot id: A0A6J3R7T8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:HSPA8
gene id: 9739:HSPA8
uniprot id: A0A6J3RTS7
names: Similarity
messages: Belongs to the heat shock protein 70 family.

9739:RPS3A
gene id: 9739:RPS3A
uniprot id: A0A2U4AME7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs. Binds with high affinity to IPO4. Interacts with DDIT3.
messages: Cytoplasm
messages: May play a role during erythropoiesis through regulation of transcription factor DDIT3.
messages: Nucleus
messages: nucleolus

9739:GPR156
gene id: 9739:GPR156
uniprot id: A0A2U4AD21
uniprot id: A0A6J3R9Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Membrane

9739:PTPN2
gene id: 9739:PTPN2
uniprot id: A0A2U4A5N7
uniprot id: A0A2U4A5P0
uniprot id: A0A2U4A5P1
uniprot id: A0A2U4A5S9
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

9739:APOC3
gene id: 9739:APOC3
uniprot id: A0A6J3RSW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apolipoprotein C3 family.
messages: Secreted

9739:TNRC6A
gene id: 9739:TNRC6A
uniprot id: A0A2U4A8K7
uniprot id: A0A2U4A8L0
uniprot id: A0A2U4A8L2
uniprot id: A0A2U4A8L4
uniprot id: A0A2U4A8L9
uniprot id: A0A2U4A8Q4
uniprot id: A0A2U4A995
uniprot id: A0A2U4A9A0
names: Similarity
messages: Belongs to the GW182 family.

9739:CDC42BPA
gene id: 9739:CDC42BPA
uniprot id: A0A2U4A4J1
uniprot id: A0A2U4A4J5
uniprot id: A0A2U4A4J6
uniprot id: A0A2U4A4J9
uniprot id: A0A2U4A4K2
uniprot id: A0A2U4A4K3
uniprot id: A0A2U4A4K4
uniprot id: A0A2U4A4L0
uniprot id: A0A2U4A4L6
uniprot id: A0A2U4A4M0
uniprot id: A0A2U4A4M5
uniprot id: A0A2U4A5D4
uniprot id: A0A2U4A5D9
uniprot id: A0A2U4A5E4
uniprot id: A0A6J3QYG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
messages: Cytoplasm
messages: lamellipodium

9739:GATA1
gene id: 9739:GATA1
uniprot id: A0A6J3QRE5
names: Subcellular Location Annotation
messages: Nucleus

9739:CNOT10
gene id: 9739:CNOT10
uniprot id: A0A2U3V1Y2
uniprot id: A0A2U4CAJ4
uniprot id: A0A2U4CAJ5
uniprot id: A0A2U4CAK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT10 family.
messages: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.
messages: Cytoplasm
messages: Nucleus

9739:QSOX2
gene id: 9739:QSOX2
uniprot id: A0A6J3RJJ8
names: Function
names: Similarity
messages: Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.
messages: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide.

9739:LOC101329723
gene id: 9739:LOC101329723
uniprot id: A0A2U4C520
names: Similarity
messages: Belongs to the glutathione peroxidase family.

9739:TAS2R16
gene id: 9739:TAS2R16
uniprot id: A0A2U4AXW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

9739:LOC101330617
gene id: 9739:LOC101330617
uniprot id: A0A6J3R565
uniprot id: A0A6J3R7V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9739:DNAL4
gene id: 9739:DNAL4
uniprot id: A0A2U3V8P2
uniprot id: A0A2U4C0U1
uniprot id: A0A2U4C109
uniprot id: A0A2U4C144
uniprot id: A0A6J3S4Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

9739:REM2
gene id: 9739:REM2
uniprot id: A0A6J3QYJ2
uniprot id: A0A6J3QZE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. RGK family.
messages: Cell membrane

9739:TAF1A
gene id: 9739:TAF1A
uniprot id: A0A2U4A4Y6
uniprot id: A0A2U4A5S7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the transcription factor SL1/TIF-IB complex, composed of TBP and at least TAF1A, TAF1B, TAF1C and TAF1D. In the complex interacts directly with TBP, TAF1A and TAF1B. Interaction of the SL1/TIF-IB subunits with TBP excludes interaction of TBP with the transcription factor IID (TFIID) subunits.
messages: Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits.
messages: Nucleus

9739:TYROBP
gene id: 9739:TYROBP
uniprot id: A0A6J3QFD7
uniprot id: A0A6J3QFW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TYROBP family.
messages: Cell membrane
messages: Membrane

9739:CHRM4
gene id: 9739:CHRM4
uniprot id: A0A6J3RQ37
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

9739:NTRK3
gene id: 9739:NTRK3
uniprot id: A0A6J3QZQ5
uniprot id: A0A6J3R0F2
uniprot id: A0A6J3R0I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

9739:TFB2M
gene id: 9739:TFB2M
uniprot id: A0A2U4A4W7
uniprot id: A0A2U4A4Z8
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:DUSP8
gene id: 9739:DUSP8
uniprot id: A0A6J3RRW4
uniprot id: A0A6J3RSG4
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

9739:FUCA2
gene id: 9739:FUCA2
uniprot id: A0A2U3V7C1
uniprot id: A0A2U4CP59
uniprot id: A0A2U4CPG8
uniprot id: A0A6J3SAS3
names: Function
names: Similarity
names: Subunit
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
messages: Belongs to the glycosyl hydrolase 29 family.
messages: Homotetramer.

9739:NFIX
gene id: 9739:NFIX
uniprot id: A0A6J3R5H1
uniprot id: A0A6J3R5J9
uniprot id: A0A6J3R623
uniprot id: A0A6J3R628
uniprot id: A0A6J3R6F8
uniprot id: A0A6J3R6G3
uniprot id: A0A6J3R858
uniprot id: A0A6J3R862
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

9739:SLC46A1
gene id: 9739:SLC46A1
uniprot id: A0A2U3V0R7
names: Subcellular Location Annotation
messages: Membrane

9739:EPN2
gene id: 9739:EPN2
uniprot id: A0A6J3QJ49
uniprot id: A0A6J3QJ72
uniprot id: A0A6J3QJ77
uniprot id: A0A6J3QJR3
uniprot id: A0A6J3QJR7
uniprot id: A0A6J3QJT3
uniprot id: A0A6J3QJT7
uniprot id: A0A6J3QK98
names: Similarity
messages: Belongs to the epsin family.

9739:MTFR1
gene id: 9739:MTFR1
uniprot id: A0A2U4AIK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

9739:DOCK1
gene id: 9739:DOCK1
uniprot id: A0A6J3Q6Q5
names: Similarity
messages: Belongs to the DOCK family.

9739:LOC101340090
gene id: 9739:LOC101340090
uniprot id: A0A2U4C2W5
uniprot id: A0A2U4C2X3
uniprot id: A0A2U4C2Y0
uniprot id: A0A2U4C2Y3
uniprot id: A0A2U4C2Y5
uniprot id: A0A2U4C306
uniprot id: A0A2U4C331
uniprot id: A0A2U4C336
uniprot id: A0A6J3QLE0
uniprot id: A0A6J3QLZ0
uniprot id: A0A6J3QMF1
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.

9739:GNG10
gene id: 9739:GNG10
uniprot id: A0A6J3RI42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

9739:CCNG1
gene id: 9739:CCNG1
uniprot id: A0A2U3V5A8
names: Similarity
messages: Belongs to the cyclin family.

9739:AFF3
gene id: 9739:AFF3
uniprot id: A0A6J3PV73
uniprot id: A0A6J3PV75
uniprot id: A0A6J3PVH4
names: Similarity
messages: Belongs to the AF4 family.

9739:DLGAP3
gene id: 9739:DLGAP3
uniprot id: A0A6J3R823
names: Similarity
messages: Belongs to the SAPAP family.

9739:RNASET2
gene id: 9739:RNASET2
uniprot id: A0A2U3V7I4
uniprot id: A0A2U4CPS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase T2 family.
messages: Lysosome lumen

9739:EPGN
gene id: 9739:EPGN
uniprot id: A0A2U3V9Q5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:MGA
gene id: 9739:MGA
uniprot id: A0A2U4BCE2
uniprot id: A0A2U4BCE5
uniprot id: A0A2U4BCR8
uniprot id: A0A6J3QY04
uniprot id: A0A6J3QYE7
uniprot id: A0A6J3QYJ3
uniprot id: A0A6J3QYK0
uniprot id: A0A6J3QYZ4
uniprot id: A0A6J3QZX8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9739:SGTB
gene id: 9739:SGTB
uniprot id: A0A2U4AX36
uniprot id: A0A2U4AX37
names: Similarity
messages: Belongs to the SGT family.

9739:RANBP9
gene id: 9739:RANBP9
uniprot id: A0A2U4C5B4
names: Similarity
messages: Belongs to the RANBP9/10 family.

9739:OTUB2
gene id: 9739:OTUB2
uniprot id: A0A2U3ZZJ5
names: Similarity
messages: Belongs to the peptidase C65 family.

9739:MAF1
gene id: 9739:MAF1
uniprot id: A0A2U3V2H8
uniprot id: A0A2U4CM50
uniprot id: A0A2U4CMC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAF1 family.
messages: Element of the TORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.
messages: Nucleus

9739:LTB
gene id: 9739:LTB
uniprot id: A0A6J3RZG7
names: Similarity
messages: Belongs to the tumor necrosis factor family.

9739:HS6ST1
gene id: 9739:HS6ST1
uniprot id: A0A6J3RNH2
uniprot id: A0A6J3RPE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

9739:TPRA1
gene id: 9739:TPRA1
uniprot id: A0A6J3S3F4
uniprot id: A0A6J3S3K8
uniprot id: A0A6J3S3L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0359 family.
messages: Membrane

9739:CSNK2A1
gene id: 9739:CSNK2A1
uniprot id: A0A2U4CLU6
names: Similarity
messages: Belongs to the protein kinase superfamily.

9739:LOC101321095
gene id: 9739:LOC101321095
uniprot id: A0A6J3RW59
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9739:CS
gene id: 9739:CS
uniprot id: A0A2U3ZYQ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the citrate synthase family.
messages: Homodimer.
messages: Mitochondrion matrix

9739:NDUFB6
gene id: 9739:NDUFB6
uniprot id: A0A2U3V8V3
uniprot id: A0A2U3V8V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB6 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9739:SLC29A2
gene id: 9739:SLC29A2
uniprot id: A0A6J3RQT0
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Basolateral cell membrane
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Lateral cell membrane
messages: Membrane

9739:SNRNP200
gene id: 9739:SNRNP200
uniprot id: A0A6J3PX61
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

9739:ERCC4
gene id: 9739:ERCC4
uniprot id: A0A2U3V5E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPF family.
messages: Nucleus

9739:UCN
gene id: 9739:UCN
uniprot id: A0A2U3V4A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

9739:FECH
gene id: 9739:FECH
uniprot id: A0A2U4BHH7
uniprot id: A0A2U4BHH9
uniprot id: A0A2U4BHW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Mitochondrion inner membrane

9739:MAK16
gene id: 9739:MAK16
uniprot id: A0A2U3V6Z9
names: Similarity
messages: Belongs to the MAK16 family.

9739:CTNNA1
gene id: 9739:CTNNA1
uniprot id: A0A2U4AGF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction

9739:ADPRS
gene id: 9739:ADPRS
uniprot id: A0A6J3PVA9
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

9739:IDH1
gene id: 9739:IDH1
uniprot id: A0A2U4BN01
uniprot id: A0A2U4BN10
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Homodimer.

9739:LOC101321123
gene id: 9739:LOC101321123
uniprot id: A0A2U4A988
uniprot id: A0A2U4A9Z3
names: Subcellular Location Annotation
messages: Nucleus

9739:MRPL47
gene id: 9739:MRPL47
uniprot id: A0A2U4C8R0
uniprot id: A0A2U4C8S4
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

9739:IL12A
gene id: 9739:IL12A
uniprot id: A0A2U3V6X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-6 superfamily.
messages: Heterodimer with IL12B; disulfide-linked. The heterodimer is known as interleukin IL-12.
messages: Heterodimerizes with IL12B to form the IL-12 cytokine or with EBI3/IL27B to form the IL-35 cytokine. IL-12 is primarily produced by professional antigen-presenting cells (APCs) such as B-cells and dendritic cells (DCs) as well as macrophages and granulocytes and regulates T-cell and natural killer-cell responses, induces the production of interferon-gamma (IFN-gamma), favors the differentiation of T-helper 1 (Th1) cells and is an important link between innate resistance and adaptive immunity. Mechanistically, exerts its biological effects through a receptor composed of IL12R1 and IL12R2 subunits. Binding to the receptor results in the rapid tyrosine phosphorylation of a number of cellular substrates including the JAK family kinases TYK2 and JAK2. In turn, recruited STAT4 gets phosphorylated and translocates to the nucleus where it regulates cytokine/growth factor responsive genes. As part of IL-35, plays essential roles in maintaining the immune homeostasis of the liver microenvironment and functions also as an immune-suppressive cytokine. Mediates biological events through unconventional receptors composed of IL12RB2 and gp130/IL6ST heterodimers or homodimers. Signaling requires the transcription factors STAT1 and STAT4, which form a unique heterodimer that binds to distinct DNA sites.
messages: Secreted

9739:HDC
gene id: 9739:HDC
uniprot id: A0A2U3V7D1
uniprot id: A0A2U4B1U8
uniprot id: A0A2U4B284
uniprot id: A0A2U4B290
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

9739:NELL1
gene id: 9739:NELL1
uniprot id: A0A2U4CDE2
uniprot id: A0A2U4CDE3
uniprot id: A0A2U4CDF4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:HTR1F
gene id: 9739:HTR1F
uniprot id: A0A2U3V580
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
messages: Membrane

9739:LNPEP
gene id: 9739:LNPEP
uniprot id: A0A2U4AW87
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Membrane

9739:LOC101321469
gene id: 9739:LOC101321469
uniprot id: A0A2U4CM09
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9739:ATP5IF1
gene id: 9739:ATP5IF1
uniprot id: A0A2U3V0R3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase inhibitor family.
messages: Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase.
messages: Forms an alpha-helical dimer with monomers associated via an antiparallel alpha-helical coiled coil, leaving each N-terminal inhibitory region accessible for interaction with an F1 catalytic domain. The inhibitory N-terminal region binds the alpha(ADP-bound)-beta(ADP-bound) (ATP5F1A-ATP5F1B) interface of F1-ATPase, and also contact the central gamma subunit (ATP5F1C). This dimeric state is favored by pH values below 7.0, and at higher values the dimers associate to form inactive homotetramer, where the inhibitory region is occluded, masking its inhibitory activity.
messages: Homodimer; represents the active form and is present at a pH value below 6.5. Homotetramer; represents the inactive form and is present at a pH value above 7.0.
messages: Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing fech to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme.
messages: Mitochondrion

9739:OGDH
gene id: 9739:OGDH
uniprot id: A0A6J3RW02
uniprot id: A0A6J3RW27
uniprot id: A0A6J3RW35
uniprot id: A0A6J3RWK4
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

9739:SLC39A14
gene id: 9739:SLC39A14
uniprot id: A0A6J3RFU7
names: Subcellular Location Annotation
messages: Membrane

9739:TRMT2A
gene id: 9739:TRMT2A
uniprot id: A0A6J3PTR0
uniprot id: A0A6J3PTT1
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:OTX1
gene id: 9739:OTX1
uniprot id: A0A6J3PWI7
names: Subcellular Location Annotation
messages: Nucleus

9739:SNX32
gene id: 9739:SNX32
uniprot id: A0A6J3RQK9
uniprot id: A0A6J3RQV9
uniprot id: A0A6J3RR22
uniprot id: A0A6J3RRJ4
uniprot id: A0A6J3RRK2
names: Function
names: Similarity
messages: Belongs to the sorting nexin family.
messages: Involved in several stages of intracellular trafficking.

9739:TRMT112
gene id: 9739:TRMT112
uniprot id: A0A6J3RQ43
names: Similarity
messages: Belongs to the TRM112 family.

9739:EML6
gene id: 9739:EML6
uniprot id: A0A6J3PVF8
names: Function
messages: May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.

9739:CAMTA2
gene id: 9739:CAMTA2
uniprot id: A0A6J3QKA6
uniprot id: A0A6J3QKC0
uniprot id: A0A6J3QKF3
uniprot id: A0A6J3QKF8
uniprot id: A0A6J3QKG2
uniprot id: A0A6J3QKY9
uniprot id: A0A6J3QKZ2
names: Similarity
names: Subunit
messages: Belongs to the CAMTA family.
messages: May interact with calmodulin.

9739:RORC
gene id: 9739:RORC
uniprot id: A0A6J3RK49
uniprot id: A0A6J3RK60
uniprot id: A0A6J3RK70
uniprot id: A0A6J3RLS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

9739:LOC101315674
gene id: 9739:LOC101315674
uniprot id: A0A6J3QZE7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

9739:PLA2G4F
gene id: 9739:PLA2G4F
uniprot id: A0A6J3QY28
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

9739:RCAN3
gene id: 9739:RCAN3
uniprot id: A0A2U4BLE5
uniprot id: A0A2U4BLE6
uniprot id: A0A2U4BLI9
uniprot id: A0A2U4BLS1
names: Similarity
messages: Belongs to the RCAN family.

9739:LOC101329054
gene id: 9739:LOC101329054
uniprot id: A0A2U4CC33
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

9739:FAM126A
gene id: 9739:FAM126A
uniprot id: A0A2U4AT85
uniprot id: A0A2U4ATQ5
uniprot id: A0A6J3RWF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Hyccin family.
messages: Cell membrane
messages: Membrane
messages: cytosol

9739:BSCL2
gene id: 9739:BSCL2
uniprot id: A0A6J3RPT0
uniprot id: A0A6J3RPV9
uniprot id: A0A6J3RQ80
uniprot id: A0A6J3RQA4
uniprot id: A0A6J3RQA9
uniprot id: A0A6J3RQW4
uniprot id: A0A6J3RQW8
uniprot id: A0A6J3RQX6
uniprot id: A0A6J3RQY0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:NTF3
gene id: 9739:NTF3
uniprot id: A0A6J3S7Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Secreted
messages: Seems to promote the survival of visceral and proprioceptive sensory neurons.

9739:BMPR1A
gene id: 9739:BMPR1A
uniprot id: A0A2U4AKH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

9739:CCNF
gene id: 9739:CCNF
uniprot id: A0A6J3Q0P6
uniprot id: A0A6J3Q0S4
uniprot id: A0A6J3Q1C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family.
messages: Nucleus
messages: centriole
messages: perinuclear region

9739:RAB27B
gene id: 9739:RAB27B
uniprot id: A0A2U4BHF0
uniprot id: A0A2U4BHF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

9739:TRIM45
gene id: 9739:TRIM45
uniprot id: A0A2U3V5L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIM/RBCC family.
messages: Cytoplasm

9739:LACTB2
gene id: 9739:LACTB2
uniprot id: A0A2U4AIM9
names: Function
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.

9739:DDR2
gene id: 9739:DDR2
uniprot id: A0A2U4B2T8
uniprot id: A0A6J3RA01
names: Subcellular Location Annotation
messages: Membrane

9739:DUSP16
gene id: 9739:DUSP16
uniprot id: A0A2U4BJB4
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

9739:PTGES3
gene id: 9739:PTGES3
uniprot id: A0A2U3V233
uniprot id: A0A2U3V2E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the p23/wos2 family.
messages: Cytoplasm
messages: Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation.
messages: Forms a complex with HSP70, HSP90 and other chaperones.

9739:NRG3
gene id: 9739:NRG3
uniprot id: A0A6J3Q697
uniprot id: A0A6J3Q6A8
uniprot id: A0A6J3Q6M3
uniprot id: A0A6J3Q735
names: Caution
names: Similarity
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:LOC101318103
gene id: 9739:LOC101318103
uniprot id: A0A6J3QQG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiA prenyltransferase family.
messages: Converts protoheme IX and farnesyl diphosphate to heme O.
messages: Membrane
messages: Mitochondrion membrane

9739:TIGD3
gene id: 9739:TIGD3
uniprot id: A0A2U3V338
names: Subcellular Location Annotation
messages: Nucleus

9739:RCE1
gene id: 9739:RCE1
uniprot id: A0A6J3RQZ4
uniprot id: A0A6J3RQZ8
uniprot id: A0A6J3RR03
uniprot id: A0A6J3RR08
uniprot id: A0A6J3RR73
uniprot id: A0A6J3RRE4
uniprot id: A0A6J3RRF2
uniprot id: A0A6J3RRF8
uniprot id: A0A6J3RRU1
uniprot id: A0A6J3RRU5
uniprot id: A0A6J3RRV0
uniprot id: A0A6J3RRV7
uniprot id: A0A6J3RRW2
uniprot id: A0A6J3RRW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U48 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:C13H18orf25
gene id: 9739:C13H18orf25
uniprot id: A0A2U3V2T6
uniprot id: A0A2U4BH57
names: Subcellular Location Annotation
messages: Nucleus

9739:VPS18
gene id: 9739:VPS18
uniprot id: A0A2U3V3I7
uniprot id: A0A2U4BCC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS18 family.
messages: Membrane

9739:IL17A
gene id: 9739:IL17A
uniprot id: A0A2U3V7J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

9739:FOXI1
gene id: 9739:FOXI1
uniprot id: A0A2U3UZE9
names: Subcellular Location Annotation
messages: Nucleus

9739:LOC101328855
gene id: 9739:LOC101328855
uniprot id: A0A6J3S9Q4
uniprot id: A0A6J3SAZ3
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

9739:BAK1
gene id: 9739:BAK1
uniprot id: A0A6J3S1B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane

9739:SH3BGRL2
gene id: 9739:SH3BGRL2
uniprot id: A0A2U4AVA6
names: Similarity
messages: Belongs to the SH3BGR family.

9739:LOC101333190
gene id: 9739:LOC101333190
uniprot id: A0A2U4BSC7
names: Function
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.

9739:TPM4
gene id: 9739:TPM4
uniprot id: A0A6J3R4G3
uniprot id: A0A6J3R4P1
uniprot id: A0A6J3R5E8
uniprot id: A0A6J3R6Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

9739:LOC101327407
gene id: 9739:LOC101327407
uniprot id: A0A6J3QTZ1
names: Similarity
messages: Belongs to the protein kinase superfamily.

9739:LOC101315560
gene id: 9739:LOC101315560
uniprot id: A0A6J3PUQ8
names: Similarity
messages: Belongs to the serpin family.

9739:HECW2
gene id: 9739:HECW2
uniprot id: A0A2U4BNJ8
uniprot id: A0A6J3RLX8
uniprot id: A0A6J3RMA4
uniprot id: A0A6J3RMS0
uniprot id: A0A6J3RNA3
uniprot id: A0A6J3RNK5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:MAPK1IP1L
gene id: 9739:MAPK1IP1L
uniprot id: A0A2U4AF10
names: Similarity
messages: Belongs to the MISS family.

9739:FAM163A
gene id: 9739:FAM163A
uniprot id: A0A6J3R8C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

9739:PTPN1
gene id: 9739:PTPN1
uniprot id: A0A2U3V2P5
uniprot id: A0A2U4C1R3
uniprot id: A0A2U4C1R4
uniprot id: A0A2U4C1U2
uniprot id: A0A2U4C200
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

9739:C1H1orf74
gene id: 9739:C1H1orf74
uniprot id: A0A2U4CR62
names: Similarity
messages: Belongs to the UPF0739 family.

9739:PCID2
gene id: 9739:PCID2
uniprot id: A0A2U4A6A8
uniprot id: A0A6J3QBU7
uniprot id: A0A6J3QC22
names: Similarity
messages: Belongs to the CSN12 family.

9739:TRMT61A
gene id: 9739:TRMT61A
uniprot id: A0A2U4CPP8
uniprot id: A0A2U4CPY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
messages: Nucleus

9739:PRSS36
gene id: 9739:PRSS36
uniprot id: A0A2U3V9V1
uniprot id: A0A2U3VA88
uniprot id: A0A2U4A8F7
names: Function
names: Subcellular Location Annotation
messages: Serine protease. Has a preference for substrates with an Arg instead of a Lys residue in position P1.
messages: extracellular matrix

9739:TADA2A
gene id: 9739:TADA2A
uniprot id: A0A6J3QNT9
uniprot id: A0A6J3QPC9
uniprot id: A0A6J3QPM8
uniprot id: A0A6J3QQ06
names: Subcellular Location Annotation
messages: Nucleus

9739:LOC117312603
gene id: 9739:LOC117312603
uniprot id: A0A6J3RGX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

9739:NUDT4
gene id: 9739:NUDT4
uniprot id: A0A6J3S5M2
uniprot id: A0A6J3S6Q9
names: Similarity
messages: Belongs to the Nudix hydrolase family. DIPP subfamily.

9739:ASB17
gene id: 9739:ASB17
uniprot id: A0A2U3V9V6
names: Function
messages: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

9739:PA2G4
gene id: 9739:PA2G4
uniprot id: A0A2U4CQJ1
names: Similarity
messages: Belongs to the peptidase M24 family.

9739:DCK
gene id: 9739:DCK
uniprot id: A0A2U4B4U6
uniprot id: A0A2U4B4V3
uniprot id: A0A2U4B4V9
uniprot id: A0A2U4B501
uniprot id: A0A2U4B588
names: Similarity
messages: Belongs to the DCK/DGK family.

9739:XPNPEP1
gene id: 9739:XPNPEP1
uniprot id: A0A2U4BQM7
uniprot id: A0A2U4BQT8
uniprot id: A0A6J3Q4Y8
names: Similarity
messages: Belongs to the peptidase M24B family.

9739:LOC101335869
gene id: 9739:LOC101335869
uniprot id: A0A2U4C6P0
uniprot id: A0A2U4C6R3
uniprot id: A0A2U4C6Z6
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

9739:EXT1
gene id: 9739:EXT1
uniprot id: A0A2U4B3K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9739:TIGD6
gene id: 9739:TIGD6
uniprot id: A0A2U4AH26
names: Subcellular Location Annotation
messages: Nucleus

9739:KPNA6
gene id: 9739:KPNA6
uniprot id: A0A2U4BKP5
uniprot id: A0A2U4BKP8
uniprot id: A0A2U4BKQ3
uniprot id: A0A2U4BL22
names: Function
names: Similarity
messages: Belongs to the importin alpha family.
messages: Functions in nuclear protein import.

9739:PXMP2
gene id: 9739:PXMP2
uniprot id: A0A6J3PRI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

9739:BICD1
gene id: 9739:BICD1
uniprot id: A0A2U4BKB1
uniprot id: A0A2U4BKD7
uniprot id: A0A2U4BKR3
uniprot id: A0A6J3S717
uniprot id: A0A6J3S8K2
uniprot id: A0A6J3S8U8
names: Similarity
messages: Belongs to the BicD family.

9739:TASOR
gene id: 9739:TASOR
uniprot id: A0A2U4CCA6
uniprot id: A0A2U4CCA8
uniprot id: A0A2U4CCB0
uniprot id: A0A2U4CCB3
uniprot id: A0A2U4CCB9
uniprot id: A0A2U4CCD6
uniprot id: A0A6J3S344
names: Similarity
messages: Belongs to the TASOR family.

9739:CSNK1G3
gene id: 9739:CSNK1G3
uniprot id: A0A2U4BTB6
uniprot id: A0A2U4BTC8
uniprot id: A0A2U4BTD3
uniprot id: A0A2U4BTD5
uniprot id: A0A2U4BTJ2
uniprot id: A0A2U4BTP0
uniprot id: A0A6J3R2S1
uniprot id: A0A6J3R369
uniprot id: A0A6J3R4U4
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

9739:CLDN11
gene id: 9739:CLDN11
uniprot id: A0A2U3V5E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9739:PSMB5
gene id: 9739:PSMB5
uniprot id: A0A2U3V0A5
uniprot id: A0A2U4CFD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

9739:DLK2
gene id: 9739:DLK2
uniprot id: A0A6J3RZN5
uniprot id: A0A6J3RZP0
uniprot id: A0A6J3S051
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:PHC3
gene id: 9739:PHC3
uniprot id: A0A2U4C864
uniprot id: A0A2U4C873
uniprot id: A0A2U4C8F7
uniprot id: A0A6J3R919
uniprot id: A0A6J3R982
uniprot id: A0A6J3RA63
names: Subcellular Location Annotation
messages: Nucleus

9739:TAF15
gene id: 9739:TAF15
uniprot id: A0A2U4C6F1
uniprot id: A0A6J3QL75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TET family.
messages: Nucleus

9739:DGKA
gene id: 9739:DGKA
uniprot id: A0A2U4CRF7
uniprot id: A0A6J3S651
uniprot id: A0A6J3S7J4
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic diacylglycerol kinase family.
messages: Monomer.

9739:INPP5J
gene id: 9739:INPP5J
uniprot id: A0A6J3PTL0
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.

9739:SLX4
gene id: 9739:SLX4
uniprot id: A0A6J3PZG0
uniprot id: A0A6J3PZV5
names: Similarity
messages: Belongs to the SLX4 family.

9739:CDC20B
gene id: 9739:CDC20B
uniprot id: A0A2U4AXD2
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

9739:CHRNA4
gene id: 9739:CHRNA4
uniprot id: A0A6J3Q1R0
uniprot id: A0A6J3Q218
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9739:LOC101334530
gene id: 9739:LOC101334530
uniprot id: A0A6J3QMD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAM family.
messages: Nucleus

9739:LOC117311044
gene id: 9739:LOC117311044
uniprot id: A0A6J3QYQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PHAX family.
messages: Cytoplasm

9739:SMOC2
gene id: 9739:SMOC2
uniprot id: A0A2U4CPE8
uniprot id: A0A2U4CPE9
uniprot id: A0A2U4CPF6
uniprot id: A0A2U4CPQ5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:GFRAL
gene id: 9739:GFRAL
uniprot id: A0A2U4B1L6
names: Similarity
messages: Belongs to the GDNFR family.

9739:EMG1
gene id: 9739:EMG1
uniprot id: A0A2U3V175
uniprot id: A0A2U4AL81
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.

9739:GPAM
gene id: 9739:GPAM
uniprot id: A0A2U4BQQ7
uniprot id: A0A2U4BQW7
uniprot id: A0A2U4BR24
uniprot id: A0A6J3Q5Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipids biosynthesis such as triglycerides, phosphatidic acids and lysophosphatidic acids.
messages: Mitochondrion outer membrane

9739:LMOD3
gene id: 9739:LMOD3
uniprot id: A0A2U4CCV0
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

9739:ZDHHC9
gene id: 9739:ZDHHC9
uniprot id: A0A2U4CHK5
uniprot id: A0A2U4CHL2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9739:TEX13D
gene id: 9739:TEX13D
uniprot id: A0A2U4CHU0
names: Similarity
messages: Belongs to the TEX13 family.

9739:SPESP1
gene id: 9739:SPESP1
uniprot id: A0A2U4CLZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPESP1 family.
messages: Involved in fertilization ability of sperm.
messages: acrosome

9739:ANP32B
gene id: 9739:ANP32B
uniprot id: A0A2U4CGQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANP32 family.
messages: Multifunctional protein that is involved in the regulation of many processes.
messages: Nucleus

9739:LOC101316288
gene id: 9739:LOC101316288
uniprot id: A0A6J3R8K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-3 family.
messages: Secreted

9739:MYD88
gene id: 9739:MYD88
uniprot id: A0A6J3S0R3
uniprot id: A0A6J3S0X8
uniprot id: A0A6J3S1V6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
messages: Cytoplasm
messages: Homodimer. Also forms heterodimers with TIRAP. Binds to TLR2, TLR4, IRAK1, IRAK2 and IRAK4 via their respective TIR domains.

9739:NUP88
gene id: 9739:NUP88
uniprot id: A0A2U3V3T9
names: Subcellular Location Annotation
messages: nuclear pore complex

9739:KCNQ5
gene id: 9739:KCNQ5
uniprot id: A0A2U4AV51
uniprot id: A0A6J3S8F5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9739:PKMYT1
gene id: 9739:PKMYT1
uniprot id: A0A6J3PYQ4
names: Similarity
messages: Belongs to the protein kinase superfamily.

9739:OSBPL10
gene id: 9739:OSBPL10
uniprot id: A0A6J3S0K0
uniprot id: A0A6J3S0Q9
uniprot id: A0A6J3S167
uniprot id: A0A6J3S1M9
names: Similarity
messages: Belongs to the OSBP family.

9739:EXOC6B
gene id: 9739:EXOC6B
uniprot id: A0A2U4BY45
uniprot id: A0A6J3PVR6
uniprot id: A0A6J3PVS0
uniprot id: A0A6J3PVS1
uniprot id: A0A6J3PW02
uniprot id: A0A6J3PW06
uniprot id: A0A6J3PWD2
names: Function
names: Similarity
messages: Belongs to the SEC15 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

9739:AP4M1
gene id: 9739:AP4M1
uniprot id: A0A6J3Q2Q0
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

9739:NSMCE4A
gene id: 9739:NSMCE4A
uniprot id: A0A2U3V7U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE4 family.
messages: Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
messages: Component of the SMC5-SMC6 complex.
messages: Nucleus
messages: telomere

9739:WDPCP
gene id: 9739:WDPCP
uniprot id: A0A6J3PX78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat fritz family.
messages: Cell membrane
messages: Membrane
messages: cilium axoneme

9739:CORO1A
gene id: 9739:CORO1A
uniprot id: A0A6J3Q152
uniprot id: A0A6J3Q1E6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat coronin family.
messages: Binds actin.
messages: Membrane
messages: cell cortex
messages: cytoskeleton
messages: phagosome membrane

9739:OPTN
gene id: 9739:OPTN
uniprot id: A0A2U4B701
uniprot id: A0A2U4B703
uniprot id: A0A2U4B704
uniprot id: A0A2U4B7E8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Golgi apparatus
messages: May act by regulating membrane trafficking and cellular morphogenesis.
messages: Recycling endosome
messages: autophagosome
messages: perinuclear region
messages: trans-Golgi network

9739:NIPAL1
gene id: 9739:NIPAL1
uniprot id: A0A2U3V288
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

9739:PPP1R10
gene id: 9739:PPP1R10
uniprot id: A0A6J3RYY9
uniprot id: A0A6J3RYZ4
uniprot id: A0A6J3RZ39
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Scaffold protein which mediates the formation of the PTW/PP1 phosphatase complex by providing a binding platform to each component of the complex. The PTW/PP1 phosphatase complex plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Mediates interaction of WDR82 and PPP1CA. Inhibitor of PPP1CA and PPP1CC phosphatase activities. Has inhibitory activity on PPP1CA only when phosphorylated. Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) homopolymers.

9739:ZSCAN12
gene id: 9739:ZSCAN12
uniprot id: A0A2U3V1H9
uniprot id: A0A6J3RY72
names: Subcellular Location Annotation
messages: Nucleus

9739:LOC101331117
gene id: 9739:LOC101331117
uniprot id: A0A2U4AKY1
uniprot id: A0A6J3S7E3
uniprot id: A0A6J3S7P5
uniprot id: A0A6J3S964
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:AMIGO2
gene id: 9739:AMIGO2
uniprot id: A0A2U4B8Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. AMIGO family.
messages: Membrane

9739:MAB21L3
gene id: 9739:MAB21L3
uniprot id: A0A2U4A1U5
names: Similarity
messages: Belongs to the mab-21 family.

9739:PLA2G5
gene id: 9739:PLA2G5
uniprot id: A0A2U4A0G5
uniprot id: A0A2U4A0G6
uniprot id: A0A2U4A1G0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

9739:CLDN19
gene id: 9739:CLDN19
uniprot id: A0A6J3PRD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9739:NPW
gene id: 9739:NPW
uniprot id: A0A6J3Q1A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuropeptide B/W family.
messages: Secreted

9739:SPTAN1
gene id: 9739:SPTAN1
uniprot id: A0A2U4CH29
uniprot id: A0A2U4CH35
uniprot id: A0A2U4CH40
uniprot id: A0A2U4CH45
uniprot id: A0A2U4CH51
uniprot id: A0A2U4CH55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spectrin family.
messages: cell cortex
messages: cytoskeleton

9739:ELMO2
gene id: 9739:ELMO2
uniprot id: A0A2U4C256
uniprot id: A0A2U4C270
uniprot id: A0A2U4C2A6
uniprot id: A0A2U4C2F2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

9739:DSG3
gene id: 9739:DSG3
uniprot id: A0A2U3V8G2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: desmosome

9739:POFUT2
gene id: 9739:POFUT2
uniprot id: A0A2U4ACT1
uniprot id: A0A2U4ADD7
names: Similarity
messages: Belongs to the glycosyltransferase 68 family.

9739:LOC101327435
gene id: 9739:LOC101327435
uniprot id: A0A6J3QJ54
names: Subcellular Location Annotation
messages: Cytoplasmic granule

9739:LOC109552641
gene id: 9739:LOC109552641
uniprot id: A0A6J3Q158
uniprot id: A0A6J3Q198
names: Subcellular Location Annotation
messages: Nucleus

9739:APOA1
gene id: 9739:APOA1
uniprot id: P0DMB0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Belongs to the apolipoprotein A1/A4/E family.
messages: Glycosylated.
messages: Homodimer (By similarity). Interacts with APOA1BP and CLU. Component of a sperm activating protein complex (SPAP), consisting of APOA1, an immunoglobulin heavy chain, an immunoglobulin light chain and albumin. Interacts with NDRG1. Interacts with SCGB3A2 (By similarity). Interacts with NAXE and YJEFN3 (By similarity).
messages: Major protein of plasma HDL, also found in chylomicrons.
messages: Palmitoylated.
messages: Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility (By similarity).
messages: Phosphorylation sites are present in the extracellular medium.
messages: Secreted

9739:PLIN3
gene id: 9739:PLIN3
uniprot id: A0A6J3R6X3
uniprot id: A0A6J3R9L1
names: Similarity
messages: Belongs to the perilipin family.

9739:SAE1
gene id: 9739:SAE1
uniprot id: A0A2U4BBM7
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

9739:SUSD4
gene id: 9739:SUSD4
uniprot id: A0A6J3QX36
uniprot id: A0A6J3QXS4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:UBAP2
gene id: 9739:UBAP2
uniprot id: A0A6J3RGF1
uniprot id: A0A6J3RGF7
uniprot id: A0A6J3RGG2
uniprot id: A0A6J3RGM8
uniprot id: A0A6J3RGN4
uniprot id: A0A6J3RGP1
uniprot id: A0A6J3RGP7
uniprot id: A0A6J3RGX3
uniprot id: A0A6J3RGX6
uniprot id: A0A6J3RGY1
uniprot id: A0A6J3RHA4
uniprot id: A0A6J3RHA9
uniprot id: A0A6J3RHB4
uniprot id: A0A6J3RIM1
uniprot id: A0A6J3RIM6
uniprot id: A0A6J3RIN5
names: Subcellular Location Annotation
messages: Cytoplasm

9739:PDE6A
gene id: 9739:PDE6A
uniprot id: A0A2U4AH15
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9739:HCRT
gene id: 9739:HCRT
uniprot id: A0A2U4BP27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the orexin family.
messages: Endoplasmic reticulum
messages: Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested.
messages: Rough endoplasmic reticulum
messages: Synapse
messages: Vesicle

9739:TBX4
gene id: 9739:TBX4
uniprot id: A0A6J3QMX3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9739:TPPP2
gene id: 9739:TPPP2
uniprot id: A0A2U4BBZ6
names: Similarity
messages: Belongs to the TPPP family.

9739:LOC117311115
gene id: 9739:LOC117311115
uniprot id: A0A6J3QZL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

9739:REC8
gene id: 9739:REC8
uniprot id: A0A6J3QXC1
uniprot id: A0A6J3QXT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

9739:NIBAN3
gene id: 9739:NIBAN3
uniprot id: A0A2U3VAK0
uniprot id: A0A2U4B260
uniprot id: A0A6J3R4T2
uniprot id: A0A6J3R5S1
names: Similarity
messages: Belongs to the Niban family.

9739:RAG2
gene id: 9739:RAG2
uniprot id: A0A2U4CER5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAG2 family.
messages: Nucleus

9739:PPP5C
gene id: 9739:PPP5C
uniprot id: A0A6J3QBX7
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.

9739:LOC117309078
gene id: 9739:LOC117309078
uniprot id: A0A6J3QVJ7
names: Function
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.
messages: Metallothioneins have a high content of cysteine residues that bind various heavy metals.

9739:INTU
gene id: 9739:INTU
uniprot id: A0A2U3V4M8
uniprot id: A0A6J3RCR5
uniprot id: A0A6J3RCU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inturned family.
messages: Cell surface
messages: cilium basal body

9739:HAP1
gene id: 9739:HAP1
uniprot id: A0A6J3QJZ9
uniprot id: A0A6J3QK03
uniprot id: A0A6J3QK55
uniprot id: A0A6J3QKM7
uniprot id: A0A6J3QKQ7
uniprot id: A0A6J3QKR2
uniprot id: A0A6J3QL44
names: Subcellular Location Annotation
messages: Early endosome
messages: Mitochondrion

9739:XPNPEP2
gene id: 9739:XPNPEP2
uniprot id: A0A6J3QSS6
names: Similarity
messages: Belongs to the peptidase M24B family.

9739:DPY19L2
gene id: 9739:DPY19L2
uniprot id: A0A2U4AJN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

9739:LOC101329117
gene id: 9739:LOC101329117
uniprot id: A0A6J3Q6B0
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Involved in nucleotide metabolism via production of dUMP, the immediate precursor of thymidine nucleotides, and decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

9739:LOC101332328
gene id: 9739:LOC101332328
uniprot id: A0A2U4C5J0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9739:SPATS2L
gene id: 9739:SPATS2L
uniprot id: A0A2U4BNG8
uniprot id: A0A2U4BNL6
uniprot id: A0A2U4BNT1
names: Similarity
messages: Belongs to the SPATS2 family.

9739:CHD9
gene id: 9739:CHD9
uniprot id: A0A2U4B4B3
uniprot id: A0A2U4B4B6
uniprot id: A0A2U4B4C4
uniprot id: A0A2U4B4D9
uniprot id: A0A2U4B4H6
uniprot id: A0A2U4B4I2
uniprot id: A0A2U4B4S4
uniprot id: A0A6J3QGP3
names: Similarity
messages: Belongs to the SNF2/RAD54 helicase family.

9739:PLOD1
gene id: 9739:PLOD1
uniprot id: A0A6J3Q9Z4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

9739:MEX3D
gene id: 9739:MEX3D
uniprot id: A0A6J3R829
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9739:MGAM
gene id: 9739:MGAM
uniprot id: A0A2U4B861
uniprot id: A0A2U4B8C5
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:DOK5
gene id: 9739:DOK5
uniprot id: A0A2U4C2J7
names: Similarity
messages: Belongs to the DOK family. Type B subfamily.

9739:SH3GLB1
gene id: 9739:SH3GLB1
uniprot id: A0A2U4A3C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Golgi apparatus membrane
messages: Midbody
messages: Mitochondrion outer membrane
messages: autophagosome membrane

9739:CMTM8
gene id: 9739:CMTM8
uniprot id: A0A6J3S0R4
names: Subcellular Location Annotation
messages: Membrane

9739:ATP13A1
gene id: 9739:ATP13A1
uniprot id: A0A6J3R5V8
uniprot id: A0A6J3R7Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

9739:LOC101322692
gene id: 9739:LOC101322692
uniprot id: A0A2U4CHQ4
names: Similarity
messages: Belongs to the CSN9 family.

9739:IRX2
gene id: 9739:IRX2
uniprot id: A0A2U4CML7
uniprot id: A0A6J3R3Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

9739:FAM166B
gene id: 9739:FAM166B
uniprot id: A0A6J3RI14
names: Similarity
messages: Belongs to the CIMIP2 family.

9739:OSGEPL1
gene id: 9739:OSGEPL1
uniprot id: A0A2U3V285
uniprot id: A0A2U4B1M8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Mitochondrion
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.

9739:VDR
gene id: 9739:VDR
uniprot id: A0A6J3S6U1
uniprot id: A0A6J3S888
uniprot id: A0A6J3S893
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Cytoplasm
messages: Nucleus

9739:MFSD1
gene id: 9739:MFSD1
uniprot id: A0A2U4C863
uniprot id: A0A6J3R8Y0
uniprot id: A0A6J3R935
uniprot id: A0A6J3RA16
uniprot id: A0A6J3RBT4
names: Subcellular Location Annotation
messages: Membrane

9739:RBM15B
gene id: 9739:RBM15B
uniprot id: A0A2U4CCB8
names: Similarity
messages: Belongs to the RRM Spen family.

9739:LOC101333863
gene id: 9739:LOC101333863
uniprot id: A0A6J3RBC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Membrane

9739:BZW1
gene id: 9739:BZW1
uniprot id: A0A2U3V0W5
uniprot id: A0A2U4BNK4
names: Similarity
messages: Belongs to the BZW family.

9739:OLFML3
gene id: 9739:OLFML3
uniprot id: A0A2U3V962
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9739:SEC24A
gene id: 9739:SEC24A
uniprot id: A0A2U3V2K0
uniprot id: A0A2U4AG81
uniprot id: A0A2U4AGA5
uniprot id: A0A2U4AGG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

9739:FOXL1
gene id: 9739:FOXL1
uniprot id: A0A2U3UZH3
names: Subcellular Location Annotation
messages: Nucleus

9739:SFPQ
gene id: 9739:SFPQ
uniprot id: A0A6J3PVI4
uniprot id: A0A6J3PW53
names: Subcellular Location Annotation
messages: Nucleus speckle

9739:PAX9
gene id: 9739:PAX9
uniprot id: A0A2U4AF13
uniprot id: A0A6J3QXK2
names: Subcellular Location Annotation
messages: Nucleus

9739:CPXM2
gene id: 9739:CPXM2
uniprot id: A0A2U4BRB0
uniprot id: A0A2U4BRB2
uniprot id: A0A2U4BRC0
uniprot id: A0A2U4BRG9
uniprot id: A0A2U4BRM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

9739:LOC101322744
gene id: 9739:LOC101322744
uniprot id: A0A2U3VAE6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9739:MPP6
gene id: 9739:MPP6
uniprot id: A0A2U3V0N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane

9739:LOC117310175
gene id: 9739:LOC117310175
uniprot id: A0A6J3QSH5
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9739:ITGA10
gene id: 9739:ITGA10
uniprot id: A0A6J3RNC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9739:CPAMD8
gene id: 9739:CPAMD8
uniprot id: A0A6J3R5A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

9739:HS3ST2
gene id: 9739:HS3ST2
uniprot id: A0A2U4A8M6
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9739:B3GAT2
gene id: 9739:B3GAT2
uniprot id: A0A6J3S9Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

9739:SLC25A37
gene id: 9739:SLC25A37
uniprot id: A0A2U4BUH4
uniprot id: A0A6J3RGD6
uniprot id: A0A6J3RHT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9739:ADCK2
gene id: 9739:ADCK2
uniprot id: A0A6J3RXF2
uniprot id: A0A6J3RY90
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

9739:GSTCD
gene id: 9739:GSTCD
uniprot id: A0A2U4AQT3
uniprot id: A0A2U4AQT5
uniprot id: A0A2U4AQT6
uniprot id: A0A6J3RD37
names: Similarity
messages: Belongs to the GSTCD family.

9739:LDHAL6B
gene id: 9739:LDHAL6B
uniprot id: A0A2U4CNM6
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

9739:PHB
gene id: 9739:PHB
uniprot id: A0A2U3V6P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

9739:MGP
gene id: 9739:MGP
uniprot id: A0A2U4BLA0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation.
messages: Belongs to the osteocalcin/matrix Gla protein family.
messages: Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium.
messages: Requires vitamin K-dependent gamma-carboxylation for its function.
messages: Secreted

9739:NLGN1
gene id: 9739:NLGN1
uniprot id: A0A2U4C819
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

9739:SLC8A1
gene id: 9739:SLC8A1
uniprot id: A0A6J3PWV0
uniprot id: A0A6J3PWV8
uniprot id: A0A6J3PX08
uniprot id: A0A6J3PX13
uniprot id: A0A6J3PX41
uniprot id: A0A6J3PXI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

9739:LOC101333469
gene id: 9739:LOC101333469
uniprot id: A0A2U4C5I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

9739:CDK18
gene id: 9739:CDK18
uniprot id: A0A6J3R327
names: Similarity
messages: Belongs to the protein kinase superfamily.

9739:BACE2
gene id: 9739:BACE2
uniprot id: A0A2U4ACU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Endosome
messages: Membrane

9739:OSBPL5
gene id: 9739:OSBPL5
uniprot id: A0A6J3RRF0
uniprot id: A0A6J3RRF7
uniprot id: A0A6J3RRP6
uniprot id: A0A6J3RRQ1
uniprot id: A0A6J3RRZ1
uniprot id: A0A6J3RS93
names: Similarity
messages: Belongs to the OSBP family.

9739:LOC101337567
gene id: 9739:LOC101337567
uniprot id: A0A2U4AIQ3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9739:LOC109551871
gene id: 9739:LOC109551871
uniprot id: A0A6J3RBV2
names: Similarity
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.

9739:EXOC1
gene id: 9739:EXOC1
uniprot id: A0A2U4ARW6
uniprot id: A0A2U4ARX1
uniprot id: A0A2U4ARX2
uniprot id: A0A2U4ARY4
names: Similarity
messages: Belongs to the SEC3 family.

9739:GCHFR
gene id: 9739:GCHFR
uniprot id: A0A2U3VA10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GFRP family.
messages: Membrane
messages: Nucleus membrane
messages: cytosol

9739:TGM3
gene id: 9739:TGM3
uniprot id: A0A2U4CLP5
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.