941640:HF1 RS00150
gene id: 941640:HF1_RS00150
uniprot id: E8ZGK1
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

941640:HF1 RS03575
gene id: 941640:HF1_RS03575
uniprot id: E8ZHU0
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

941640:HF1 RS01285
gene id: 941640:HF1_RS01285
uniprot id: E8ZKS9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

941640:HF1 RS07415
gene id: 941640:HF1_RS07415
uniprot id: E8ZK10
names: Subcellular Location Annotation
messages: Cytoplasm

941640:HF1 RS00235
gene id: 941640:HF1_RS00235
uniprot id: E8ZGH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

941640:HF1 RS00495
gene id: 941640:HF1_RS00495
uniprot id: E8ZKD4
names: Similarity
messages: Belongs to the SHMT family.

941640:HF1 RS01230
gene id: 941640:HF1_RS01230
uniprot id: E8ZKS6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

941640:HF1 RS03500
gene id: 941640:HF1_RS03500
uniprot id: E8ZHS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

941640:HF1 RS00685
gene id: 941640:HF1_RS00685
uniprot id: E8ZKG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Membrane

941640:HF1 RS00645
gene id: 941640:HF1_RS00645
uniprot id: E8ZKF8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

941640:HF1 RS00195
gene id: 941640:HF1_RS00195
uniprot id: E8ZGH0
names: Similarity
messages: Belongs to the HPrK/P family.

941640:HF1 RS00210
gene id: 941640:HF1_RS00210
uniprot id: E8ZGH3
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

941640:HF1 RS00240
gene id: 941640:HF1_RS00240
uniprot id: E8ZK83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

941640:HF1 RS00175
gene id: 941640:HF1_RS00175
uniprot id: E8ZGK6
names: Function
names: Similarity
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.

941640:HF1 RS07280
gene id: 941640:HF1_RS07280
uniprot id: E8ZJY4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

941640:HF1 RS00015
gene id: 941640:HF1_RS00015
uniprot id: E8ZGI1
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

941640:HF1 RS00435
gene id: 941640:HF1_RS00435
uniprot id: E8ZKC2
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

941640:HF1 RS07705
gene id: 941640:HF1_RS07705
uniprot id: E8ZK65
names: Similarity
messages: Belongs to the thymidine kinase family.

941640:HF1 RS00640
gene id: 941640:HF1_RS00640
uniprot id: E8ZKF7
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.

941640:HF1 RS07745
gene id: 941640:HF1_RS07745
uniprot id: E8ZK72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MnmG family.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

941640:HF1 RS00275
gene id: 941640:HF1_RS00275
uniprot id: E8ZK90
names: Subcellular Location Annotation
messages: Membrane

941640:HF1 RS00445
gene id: 941640:HF1_RS00445
uniprot id: E8ZKC4
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

941640:HF1 RS03625
gene id: 941640:HF1_RS03625
uniprot id: E8ZHV1
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

941640:HF1 RS07785
gene id: 941640:HF1_RS07785
uniprot id: E8ZK80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Cell membrane
messages: Membrane

941640:HF1 RS07305
gene id: 941640:HF1_RS07305
uniprot id: E8ZJY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

941640:HF1 RS07410
gene id: 941640:HF1_RS07410
uniprot id: E8ZK09
names: Similarity
messages: Belongs to the pyruvate kinase family.

941640:HF1 RS00185
gene id: 941640:HF1_RS00185
uniprot id: E8ZGG8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

941640:HF1 RS07220
gene id: 941640:HF1_RS07220
uniprot id: E8ZJX2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

941640:HF1 RS07330
gene id: 941640:HF1_RS07330
uniprot id: E8ZJZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

941640:HF1 RS00655
gene id: 941640:HF1_RS00655
uniprot id: E8ZKG0
names: Subcellular Location Annotation
messages: Membrane

941640:HF1 RS07345
gene id: 941640:HF1_RS07345
uniprot id: E8ZJZ7
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

941640:HF1 RS03615
gene id: 941640:HF1_RS03615
uniprot id: E8ZHU9
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

941640:HF1 RS00710
gene id: 941640:HF1_RS00710
uniprot id: E8ZKH1
names: Function
names: Similarity
messages: Belongs to the ATPase gamma chain family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

941640:HF1 RS00390
gene id: 941640:HF1_RS00390
uniprot id: E8ZKB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

941640:HF1 RS05565
gene id: 941640:HF1_RS05565
uniprot id: E8ZIY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

941640:HF1 RS00230
gene id: 941640:HF1_RS00230
uniprot id: E8ZGH7
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

941640:HF1 RS05495
gene id: 941640:HF1_RS05495
uniprot id: E8ZIX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

941640:HF1 RS01275
gene id: 941640:HF1_RS01275
uniprot id: E8ZKS7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

941640:HF1 RS00325
gene id: 941640:HF1_RS00325
uniprot id: E8ZK99
names: Subcellular Location Annotation
messages: Membrane

941640:HF1 RS07135
gene id: 941640:HF1_RS07135
uniprot id: E8ZJV5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

941640:HF1 RS00070
gene id: 941640:HF1_RS00070
uniprot id: E8ZGJ1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

941640:HF1 RS03515
gene id: 941640:HF1_RS03515
uniprot id: E8ZHS8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

941640:HF1 RS00350
gene id: 941640:HF1_RS00350
uniprot id: E8ZKA4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

941640:HF1 RS07245
gene id: 941640:HF1_RS07245
uniprot id: E8ZJX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

941640:HF1 RS00620
gene id: 941640:HF1_RS00620
uniprot id: E8ZKF4
names: Caution
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

941640:HF1 RS05490
gene id: 941640:HF1_RS05490
uniprot id: E8ZIX3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

941640:HF1 RS00220
gene id: 941640:HF1_RS00220
uniprot id: E8ZGH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

941640:HF1 RS07155
gene id: 941640:HF1_RS07155
uniprot id: E8ZJV9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

941640:HF1 RS07420
gene id: 941640:HF1_RS07420
uniprot id: E8ZK11
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

941640:HF1 RS03655
gene id: 941640:HF1_RS03655
uniprot id: E8ZHV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

941640:HF1 RS07225
gene id: 941640:HF1_RS07225
uniprot id: E8ZJX3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

941640:HF1 RS07550
gene id: 941640:HF1_RS07550
uniprot id: E8ZK37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

941640:HF1 RS07505
gene id: 941640:HF1_RS07505
uniprot id: E8ZK28
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

941640:HF1 RS00320
gene id: 941640:HF1_RS00320
uniprot id: E8ZK98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

941640:HF1 RS00100
gene id: 941640:HF1_RS00100
uniprot id: E8ZGJ6
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.

941640:HF1 RS03495
gene id: 941640:HF1_RS03495
uniprot id: E8ZHS4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

941640:HF1 RS07790
gene id: 941640:HF1_RS07790
uniprot id: E8ZK81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

941640:HF1 RS03565
gene id: 941640:HF1_RS03565
uniprot id: E8ZHT8
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

941640:HF1 RS00005
gene id: 941640:HF1_RS00005
uniprot id: E8ZGH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

941640:HF1 RS00700
gene id: 941640:HF1_RS00700
uniprot id: E8ZKG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

941640:HF1 RS07380
gene id: 941640:HF1_RS07380
uniprot id: E8ZK03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

941640:HF1 RS00335
gene id: 941640:HF1_RS00335
uniprot id: E8ZKA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

941640:HF1 RS07500
gene id: 941640:HF1_RS07500
uniprot id: E8ZK27
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

941640:HF1 RS07240
gene id: 941640:HF1_RS07240
uniprot id: E8ZJX6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

941640:HF1 RS00520
gene id: 941640:HF1_RS00520
uniprot id: E8ZKD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

941640:HF1 RS07485
gene id: 941640:HF1_RS07485
uniprot id: E8ZK24
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

941640:HF1 RS07265
gene id: 941640:HF1_RS07265
uniprot id: E8ZJY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

941640:HF1 RS03585
gene id: 941640:HF1_RS03585
uniprot id: E8ZHU2
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

941640:HF1 RS07205
gene id: 941640:HF1_RS07205
uniprot id: E8ZJW9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

941640:HF1 RS00725
gene id: 941640:HF1_RS00725
uniprot id: E8ZKH4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

941640:HF1 RS00510
gene id: 941640:HF1_RS00510
uniprot id: E8ZKD7
names: Similarity
messages: Belongs to the RpoE family.

941640:HF1 RS00075
gene id: 941640:HF1_RS00075
uniprot id: E8ZGJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cytoplasm

941640:HF1 RS03620
gene id: 941640:HF1_RS03620
uniprot id: E8ZHV0
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

941640:HF1 RS07165
gene id: 941640:HF1_RS07165
uniprot id: E8ZJW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

941640:HF1 RS07255
gene id: 941640:HF1_RS07255
uniprot id: E8ZJX9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

941640:HF1 RS00165
gene id: 941640:HF1_RS00165
uniprot id: E8ZGK4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

941640:HF1 RS07750
gene id: 941640:HF1_RS07750
uniprot id: E8ZK73
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

941640:HF1 RS00730
gene id: 941640:HF1_RS00730
uniprot id: E8ZKH5
names: Similarity
messages: Belongs to the RRF family.

941640:HF1 RS01160
gene id: 941640:HF1_RS01160
uniprot id: E8ZKR2
names: Subcellular Location Annotation
messages: Membrane

941640:HF1 RS05515
gene id: 941640:HF1_RS05515
uniprot id: E8ZIX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

941640:HF1 RS07275
gene id: 941640:HF1_RS07275
uniprot id: E8ZJY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

941640:HF1 RS05500
gene id: 941640:HF1_RS05500
uniprot id: E8ZIX5
names: Similarity
messages: Belongs to the peptidase M17 family.

941640:HF1 RS00605
gene id: 941640:HF1_RS00605
uniprot id: E8ZKF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

941640:HF1 RS07160
gene id: 941640:HF1_RS07160
uniprot id: E8ZJW0
names: Similarity
messages: Belongs to the CTP synthase family.

941640:HF1 RS07260
gene id: 941640:HF1_RS07260
uniprot id: E8ZJY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

941640:HF1 RS03540
gene id: 941640:HF1_RS03540
uniprot id: E8ZHT3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

941640:HF1 RS00250
gene id: 941640:HF1_RS00250
uniprot id: E8ZK85
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

941640:HF1 RS07480
gene id: 941640:HF1_RS07480
uniprot id: E8ZK23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

941640:HF1 RS07715
gene id: 941640:HF1_RS07715
uniprot id: E8ZK67
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

941640:HF1 RS00180
gene id: 941640:HF1_RS00180
uniprot id: E8ZGK7
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

941640:HF1 RS00705
gene id: 941640:HF1_RS00705
uniprot id: E8ZKH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

941640:HF1 RS07720
gene id: 941640:HF1_RS07720
uniprot id: E8ZK68
names: Similarity
messages: Belongs to the phosphohexose mutase family.

941640:HF1 RS07540
gene id: 941640:HF1_RS07540
uniprot id: E8ZK35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

941640:HF1 RS07285
gene id: 941640:HF1_RS07285
uniprot id: E8ZJY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

941640:HF1 RS00285
gene id: 941640:HF1_RS00285
uniprot id: E8ZK92
names: Function
messages: Catalyzes the synthesis of GMP from XMP.

941640:HF1 RS05555
gene id: 941640:HF1_RS05555
uniprot id: E8ZIY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

941640:HF1 RS00395
gene id: 941640:HF1_RS00395
uniprot id: E8ZKB2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

941640:HF1 RS00500
gene id: 941640:HF1_RS00500
uniprot id: E8ZKD5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

941640:HF1 RS00170
gene id: 941640:HF1_RS00170
uniprot id: E8ZGK5
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

941640:HF1 RS07315
gene id: 941640:HF1_RS07315
uniprot id: E8ZJZ1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

941640:HF1 RS07145
gene id: 941640:HF1_RS07145
uniprot id: E8ZJV7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

941640:HF1 RS00255
gene id: 941640:HF1_RS00255
uniprot id: E8ZK86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

941640:HF1 RS07295
gene id: 941640:HF1_RS07295
uniprot id: E8ZJY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

941640:HF1 RS00690
gene id: 941640:HF1_RS00690
uniprot id: E8ZKG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

941640:HF1 RS05690
gene id: 941640:HF1_RS05690
uniprot id: E8ZJ12
names: Subcellular Location Annotation
messages: Membrane

941640:HF1 RS07690
gene id: 941640:HF1_RS07690
uniprot id: E8ZK62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

941640:HF1 RS00425
gene id: 941640:HF1_RS00425
uniprot id: E8ZKC0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

941640:HF1 RS00190
gene id: 941640:HF1_RS00190
uniprot id: E8ZGG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

941640:HF1 RS01290
gene id: 941640:HF1_RS01290
uniprot id: E8ZKT0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

941640:HF1 RS01210
gene id: 941640:HF1_RS01210
uniprot id: E8ZKS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

941640:HF1 RS00410
gene id: 941640:HF1_RS00410
uniprot id: E8ZKB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

941640:HF1 RS07335
gene id: 941640:HF1_RS07335
uniprot id: E8ZJZ5
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

941640:HF1 RS00600
gene id: 941640:HF1_RS00600
uniprot id: E8ZKF0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

941640:HF1 RS00225
gene id: 941640:HF1_RS00225
uniprot id: E8ZGH6
names: Subcellular Location Annotation
messages: Membrane

941640:HF1 RS07545
gene id: 941640:HF1_RS07545
uniprot id: E8ZK36
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

941640:HF1 RS00055
gene id: 941640:HF1_RS00055
uniprot id: E8ZGI8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

941640:HF1 RS05480
gene id: 941640:HF1_RS05480
uniprot id: E8ZIX1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: This protein binds to 23S rRNA in the presence of protein L20.

941640:HF1 RS07780
gene id: 941640:HF1_RS07780
uniprot id: E8ZK79
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

941640:HF1 RS03560
gene id: 941640:HF1_RS03560
uniprot id: E8ZHT7
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

941640:HF1 RS06595
gene id: 941640:HF1_RS06595
uniprot id: E8ZJJ5
names: Subcellular Location Annotation
messages: Membrane

941640:HF1 RS03600
gene id: 941640:HF1_RS03600
uniprot id: E8ZHU6
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

941640:HF1 RS07375
gene id: 941640:HF1_RS07375
uniprot id: E8ZK02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

941640:HF1 RS00145
gene id: 941640:HF1_RS00145
uniprot id: E8ZGK0
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

941640:HF1 RS07235
gene id: 941640:HF1_RS07235
uniprot id: E8ZJX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

941640:HF1 RS03450
gene id: 941640:HF1_RS03450
uniprot id: E8ZHR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

941640:HF1 RS05715
gene id: 941640:HF1_RS05715
uniprot id: E8ZJ17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

941640:HF1 RS07360
gene id: 941640:HF1_RS07360
uniprot id: E8ZK00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

941640:HF1 RS03630
gene id: 941640:HF1_RS03630
uniprot id: E8ZHV2
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

941640:HF1 RS00715
gene id: 941640:HF1_RS00715
uniprot id: E8ZKH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

941640:HF1 RS00260
gene id: 941640:HF1_RS00260
uniprot id: E8ZK87
names: Cofactor
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

941640:HF1 RS07230
gene id: 941640:HF1_RS07230
uniprot id: E8ZJX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

941640:HF1 RS03440
gene id: 941640:HF1_RS03440
uniprot id: E8ZHR4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

941640:HF1 RS00385
gene id: 941640:HF1_RS00385
uniprot id: E8ZKB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

941640:HF1 RS07320
gene id: 941640:HF1_RS07320
uniprot id: E8ZJZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

941640:HF1 RS07385
gene id: 941640:HF1_RS07385
uniprot id: E8ZK04
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S16 family.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

941640:HF1 RS06445
gene id: 941640:HF1_RS06445
uniprot id: E8ZJG5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

941640:HF1 RS07735
gene id: 941640:HF1_RS07735
uniprot id: E8ZK71
names: Similarity
messages: Belongs to the UPRTase family.

941640:HF1 RS07765
gene id: 941640:HF1_RS07765
uniprot id: E8ZK76
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

941640:HF1 RS00010
gene id: 941640:HF1_RS00010
uniprot id: E8ZGI0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA which binds and tethers DNA polymerases and other proteins to the DNA. The DNA replisome complex has a single clamp-loading complex (3 tau and 1 each of delta, delta', psi and chi subunits) which binds 3 Pol III cores (1 core on the leading strand and 2 on the lagging strand) each with a beta sliding clamp dimer. Additional proteins in the replisome are other copies of gamma, psi and chi, Ssb, DNA helicase and RNA primase.

941640:HF1 RS00525
gene id: 941640:HF1_RS00525
uniprot id: E8ZKD9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

941640:HF1 RS00540
gene id: 941640:HF1_RS00540
uniprot id: E8ZKE2
names: Similarity
messages: Belongs to the elongation factor P family.

941640:HF1 RS07440
gene id: 941640:HF1_RS07440
uniprot id: E8ZK15
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL31 family.

941640:HF1 RS03445
gene id: 941640:HF1_RS03445
uniprot id: E8ZHR5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

941640:HF1 RS00095
gene id: 941640:HF1_RS00095
uniprot id: E8ZGJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

941640:HF1 RS07355
gene id: 941640:HF1_RS07355
uniprot id: E8ZJZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

941640:HF1 RS06010
gene id: 941640:HF1_RS06010
uniprot id: E8ZJ76
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

941640:HF1 RS00440
gene id: 941640:HF1_RS00440
uniprot id: E8ZKC3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

941640:HF1 RS01305
gene id: 941640:HF1_RS01305
uniprot id: E8ZKT3
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

941640:HF1 RS01295
gene id: 941640:HF1_RS01295
uniprot id: E8ZKT1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

941640:HF1 RS03485
gene id: 941640:HF1_RS03485
uniprot id: E8ZHS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

941640:HF1 RS01130
gene id: 941640:HF1_RS01130
uniprot id: E8ZKQ8
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

941640:HF1 RS07460
gene id: 941640:HF1_RS07460
uniprot id: E8ZK19
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

941640:HF1 RS00085
gene id: 941640:HF1_RS00085
uniprot id: E8ZGJ3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

941640:HF1 RS03550
gene id: 941640:HF1_RS03550
uniprot id: E8ZHT5
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

941640:HF1 RS07195
gene id: 941640:HF1_RS07195
uniprot id: E8ZJW7
names: Similarity
messages: Belongs to the NusB family.

941640:HF1 RS00530
gene id: 941640:HF1_RS00530
uniprot id: E8ZKE0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

941640:HF1 RS05720
gene id: 941640:HF1_RS05720
uniprot id: E8ZJ18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

941640:HF1 RS00745
gene id: 941640:HF1_RS00745
uniprot id: E8ZKH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

941640:HF1 RS00490
gene id: 941640:HF1_RS00490
uniprot id: E8ZKD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

941640:HF1 RS07625
gene id: 941640:HF1_RS07625
uniprot id: E8ZK49
names: Similarity
messages: Belongs to the AdoMet synthase family.

941640:HF1 RS07725
gene id: 941640:HF1_RS07725
uniprot id: E8ZK69
names: Subcellular Location Annotation
messages: Cytoplasm

941640:HF1 RS07645
gene id: 941640:HF1_RS07645
uniprot id: E8ZK53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

941640:HF1 RS07675
gene id: 941640:HF1_RS07675
uniprot id: E8ZK59
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.

941640:HF1 RS00245
gene id: 941640:HF1_RS00245
uniprot id: E8ZK84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

941640:HF1 RS07140
gene id: 941640:HF1_RS07140
uniprot id: E8ZJV6
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.

941640:HF1 RS07210
gene id: 941640:HF1_RS07210
uniprot id: E8ZJX0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

941640:HF1 RS03570
gene id: 941640:HF1_RS03570
uniprot id: E8ZHT9
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

941640:HF1 RS07405
gene id: 941640:HF1_RS07405
uniprot id: E8ZK08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

941640:HF1 RS03635
gene id: 941640:HF1_RS03635
uniprot id: E8ZHV3
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

941640:HF1 RS00370
gene id: 941640:HF1_RS00370
uniprot id: E8ZKA7
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

941640:HF1 RS07310
gene id: 941640:HF1_RS07310
uniprot id: E8ZJZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

941640:HF1 RS07270
gene id: 941640:HF1_RS07270
uniprot id: E8ZJY2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

941640:HF1 RS03535
gene id: 941640:HF1_RS03535
uniprot id: E8ZHT2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.

941640:HF1 RS01170
gene id: 941640:HF1_RS01170
uniprot id: E8ZKR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

941640:HF1 RS05560
gene id: 941640:HF1_RS05560
uniprot id: E8ZIY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate cyclase family. DacB/CdaS subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Cell membrane
messages: Probably oligomerizes.

941640:HF1 RS00455
gene id: 941640:HF1_RS00455
uniprot id: E8ZKC6
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

941640:HF1 RS00635
gene id: 941640:HF1_RS00635
uniprot id: E8ZKF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Membrane

941640:HF1 RS07670
gene id: 941640:HF1_RS07670
uniprot id: E8ZK58
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

941640:HF1 RS07340
gene id: 941640:HF1_RS07340
uniprot id: E8ZJZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

941640:HF1 RS07350
gene id: 941640:HF1_RS07350
uniprot id: E8ZJZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

941640:HF1 RS07180
gene id: 941640:HF1_RS07180
uniprot id: E8ZJW4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

941640:HF1 RS03590
gene id: 941640:HF1_RS03590
uniprot id: E8ZHU3
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

941640:HF1 RS01300
gene id: 941640:HF1_RS01300
uniprot id: E8ZKT2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

941640:HF1 RS07250
gene id: 941640:HF1_RS07250
uniprot id: E8ZJX8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

941640:HF1 RS07325
gene id: 941640:HF1_RS07325
uniprot id: E8ZJZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

941640:HF1 RS05505
gene id: 941640:HF1_RS05505
uniprot id: E8ZIX6
names: Subcellular Location Annotation
messages: Membrane

941640:HF1 RS00050
gene id: 941640:HF1_RS00050
uniprot id: E8ZGI7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

941640:HF1 RS00625
gene id: 941640:HF1_RS00625
uniprot id: E8ZKF5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

941640:HF1 RS07290
gene id: 941640:HF1_RS07290
uniprot id: E8ZJY6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

941640:HF1 RS03645
gene id: 941640:HF1_RS03645
uniprot id: E8ZHV5
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

941640:HF1 RS03640
gene id: 941640:HF1_RS03640
uniprot id: E8ZHV4
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

941640:HF1 RS03545
gene id: 941640:HF1_RS03545
uniprot id: E8ZHT4
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

941640:HF1 RS00590
gene id: 941640:HF1_RS00590
uniprot id: E8ZKE8
names: Subcellular Location Annotation
messages: Membrane

941640:HF1 RS07400
gene id: 941640:HF1_RS07400
uniprot id: E8ZK07
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

941640:HF1 RS07445
gene id: 941640:HF1_RS07445
uniprot id: E8ZK16
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

941640:HF1 RS07300
gene id: 941640:HF1_RS07300
uniprot id: E8ZJY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

941640:HF1 RS07530
gene id: 941640:HF1_RS07530
uniprot id: E8ZK33
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.