935293:PL78 RS08410
gene id: 935293:PL78_RS08410
uniprot id: A0A3S6EZS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. TdcB also dehydrates serine to yield pyruvate via analogous enamine/imine intermediates.
messages: In the native structure, TdcB is in a dimeric form, whereas in the TdcB-AMP complex, it exists in a tetrameric form (dimer of dimers).

935293:PL78 RS01670
gene id: 935293:PL78_RS01670
uniprot id: A0A3S6EVL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

935293:PL78 RS05055
gene id: 935293:PL78_RS05055
uniprot id: A0A3S6EXL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

935293:PL78 RS10810
gene id: 935293:PL78_RS10810
uniprot id: A0A3S6F157
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

935293:PL78 RS01315
gene id: 935293:PL78_RS01315
uniprot id: A0A3S6EVH2
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

935293:PL78 RS16705
gene id: 935293:PL78_RS16705
uniprot id: A0A3S6F4B2
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

935293:PL78 RS02585
gene id: 935293:PL78_RS02585
uniprot id: A0A3S6EXU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

935293:PL78 RS08075
gene id: 935293:PL78_RS08075
uniprot id: A0A3S6EZ92
names: Similarity
messages: Belongs to the YicC/YloC family.

935293:PL78 RS07830
gene id: 935293:PL78_RS07830
uniprot id: A0A3S6F051
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

935293:PL78 RS14020
gene id: 935293:PL78_RS14020
uniprot id: A0A3S6F2G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

935293:PL78 RS16345
gene id: 935293:PL78_RS16345
uniprot id: A0A3S6F3Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

935293:PL78 RS14065
gene id: 935293:PL78_RS14065
uniprot id: A0A3S6F2V1
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
messages: Repressed under conditions of excess protein secretion capacity and derepressed when protein secretion becomes limiting. This is regulated by SecM.

935293:PL78 RS11700
gene id: 935293:PL78_RS11700
uniprot id: A0A3S6F2V4
names: Subcellular Location Annotation
messages: Cell inner membrane

935293:PL78 RS17365
gene id: 935293:PL78_RS17365
uniprot id: A0A3S6F5F1
names: Subcellular Location Annotation
messages: Cytoplasm

935293:PL78 RS05105
gene id: 935293:PL78_RS05105
uniprot id: A0A3S6EXM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNR ribonuclease family. RNase II subfamily.
messages: Cytoplasm
messages: Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.

935293:PL78 RS09505
gene id: 935293:PL78_RS09505
uniprot id: A0A3S6F0D7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

935293:PL78 RS09105
gene id: 935293:PL78_RS09105
uniprot id: A0A3S6F1C6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

935293:PL78 RS03765
gene id: 935293:PL78_RS03765
uniprot id: B6A877
names: Activity Regulation
names: Disruption Phenotype
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cells with a disrupted yenA1-yenA2-chi2-yenB-yenC1-yenC2 locus are no longer pathogenic in C.zealandica larvae.
messages: Part of an orally active toxin complex (TC) with strong insecticidal effects on larvae of the Coleoptera Costelytra zealandica, Acrossidius tasmania and Adoryphorus couloni and some Lepidoptera larvae (PubMed:21278295, PubMed:22158901). The TC has an endochitinase activity (PubMed:21278295) (Probable).
messages: Secreted
messages: Semipurified toxin complex consists of at least YenA1, YenA2, YenB, YenC1, YenC2, Chi1 and Chi2 (PubMed:21278295). The Yen-TC:K9 subcomplex is about 26 nm tall and 22 nm in diameter with 5-fold symmetry and 5 copies of YenA1, YenA2, Chi1 and Chi2; the chitinase subunits may be solvent accessible on the exterior the complex (PubMed:22158901). The Yen-TC:K9 subcomplex has no insecticidal activity (PubMed:22158901). The native complex with additional YenB, YenC1 and YenC2 subunits is 16 nm taller and is insecticidal; the toxicity-conferring subunits are present at about 1 copy each (PubMed:22158901).
messages: Toxin complex is secreted when grown at 25 degrees Celsius or less; at higher temperatures the proteins are present intracellularly but not secreted.

935293:PL78 RS04825
gene id: 935293:PL78_RS04825
uniprot id: A0A3S6EXX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

935293:PL78 RS17280
gene id: 935293:PL78_RS17280
uniprot id: A0A3S6F5Z3
names: Similarity
messages: Belongs to the UPF0265 family.

935293:PL78 RS17720
gene id: 935293:PL78_RS17720
uniprot id: A0A3S6F4L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

935293:PL78 RS13990
gene id: 935293:PL78_RS13990
uniprot id: A0A3S6F2I7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

935293:PL78 RS01470
gene id: 935293:PL78_RS01470
uniprot id: A0A3S6EVS3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

935293:PL78 RS01440
gene id: 935293:PL78_RS01440
uniprot id: A0A3S6EX77
names: Similarity
messages: Belongs to the citrate synthase family.

935293:PL78 RS14615
gene id: 935293:PL78_RS14615
uniprot id: A0A3S6F2U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS08650
gene id: 935293:PL78_RS08650
uniprot id: A0A3S6EZK7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

935293:PL78 RS13935
gene id: 935293:PL78_RS13935
uniprot id: A0A3S6F2F3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

935293:PL78 RS14755
gene id: 935293:PL78_RS14755
uniprot id: A0A3S6F2Z2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

935293:PL78 RS03425
gene id: 935293:PL78_RS03425
uniprot id: A0A3S6EWV8
names: Similarity
messages: Belongs to the phage antitermination Q type 1 family.

935293:PL78 RS11285
gene id: 935293:PL78_RS11285
uniprot id: A0A3S6F1D6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

935293:PL78 RS08665
gene id: 935293:PL78_RS08665
uniprot id: A0A3S6EZT6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS09910
gene id: 935293:PL78_RS09910
uniprot id: A0A3S6F0L8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

935293:PL78 RS13795
gene id: 935293:PL78_RS13795
uniprot id: A0A3S6F2H0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
messages: Homodimer.

935293:PL78 RS04175
gene id: 935293:PL78_RS04175
uniprot id: A0A3S6EYQ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

935293:PL78 RS01200
gene id: 935293:PL78_RS01200
uniprot id: A0A3S6EVD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

935293:PL78 RS16480
gene id: 935293:PL78_RS16480
uniprot id: A0A3S6F3X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a regulator of flagellar gene expression by modulating the protein level of the anti sigma factor FlgM upon sensing ring completion or hook elongation. Flk could inhibit FlgM secretion by acting as a braking system for the flagellar-associated type III secretion system.
messages: Belongs to the flk family.
messages: Cell inner membrane

935293:PL78 RS16580
gene id: 935293:PL78_RS16580
uniprot id: A0A3S6F3Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

935293:PL78 RS01730
gene id: 935293:PL78_RS01730
uniprot id: A0A3S6EXC4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

935293:PL78 RS04780
gene id: 935293:PL78_RS04780
uniprot id: A0A3S6EZ22
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

935293:PL78 RS17375
gene id: 935293:PL78_RS17375
uniprot id: A0A3S6F4K3
names: Function
messages: Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase.

935293:PL78 RS13805
gene id: 935293:PL78_RS13805
uniprot id: A0A3S6F2I3
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

935293:PL78 RS02170
gene id: 935293:PL78_RS02170
uniprot id: A0A3S6EWF7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS08130
gene id: 935293:PL78_RS08130
uniprot id: A0A3S6F0B1
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

935293:PL78 RS11420
gene id: 935293:PL78_RS11420
uniprot id: A0A3S6F251
names: Similarity
messages: Belongs to the SlyX family.

935293:PL78 RS08180
gene id: 935293:PL78_RS08180
uniprot id: A0A3S6F0C2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

935293:PL78 RS07595
gene id: 935293:PL78_RS07595
uniprot id: A0A3S6F013
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

935293:PL78 RS09395
gene id: 935293:PL78_RS09395
uniprot id: A0A3S6F0C0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

935293:PL78 RS06100
gene id: 935293:PL78_RS06100
uniprot id: A0A3S6EYC9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LplA family.
messages: Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.
messages: Cytoplasm
messages: In the transfer reaction, the free carboxyl group of lipoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.
messages: Monomer.

935293:PL78 RS16585
gene id: 935293:PL78_RS16585
uniprot id: A0A3S6F414
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS07535
gene id: 935293:PL78_RS07535
uniprot id: A0A3S6EYY8
names: Function
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.
messages: Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D-galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D-Glc4O) and L-glutamate.

935293:PL78 RS00870
gene id: 935293:PL78_RS00870
uniprot id: A0A3S6EV87
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

935293:PL78 RS18935
gene id: 935293:PL78_RS18935
uniprot id: A0A3S6F5M4
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS02605
gene id: 935293:PL78_RS02605
uniprot id: A0A3S6EX99
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. YcaD (TC 2.A.1.26) family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

935293:PL78 RS02575
gene id: 935293:PL78_RS02575
uniprot id: A0A3S6EW61
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

935293:PL78 RS06535
gene id: 935293:PL78_RS06535
uniprot id: A0A3S6EYE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

935293:PL78 RS12930
gene id: 935293:PL78_RS12930
uniprot id: A0A3S6F1W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

935293:PL78 RS02755
gene id: 935293:PL78_RS02755
uniprot id: A0A3S6EXC8
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

935293:PL78 RS15505
gene id: 935293:PL78_RS15505
uniprot id: A0A3S6F3J7
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

935293:PL78 RS11005
gene id: 935293:PL78_RS11005
uniprot id: A0A3S6F0U2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

935293:PL78 RS11405
gene id: 935293:PL78_RS11405
uniprot id: A0A3S6F108
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm
messages: Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE.

935293:PL78 RS05725
gene id: 935293:PL78_RS05725
uniprot id: A0A3S6EY10
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

935293:PL78 RS08330
gene id: 935293:PL78_RS08330
uniprot id: A0A3S6F0F3
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

935293:PL78 RS08400
gene id: 935293:PL78_RS08400
uniprot id: A0A3S6EZT9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetokinase family. TdcD subfamily.
messages: Catalyzes the conversion of propionyl phosphate and ADP to propionate and ATP.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS01880
gene id: 935293:PL78_RS01880
uniprot id: A0A3S6EXF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

935293:PL78 RS05695
gene id: 935293:PL78_RS05695
uniprot id: A0A3S6EYA5
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS01435
gene id: 935293:PL78_RS01435
uniprot id: A0A3S6EVZ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

935293:PL78 RS10710
gene id: 935293:PL78_RS10710
uniprot id: A0A3S6F138
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AaeX family.
messages: Cell membrane

935293:PL78 RS07860
gene id: 935293:PL78_RS07860
uniprot id: A0A3S6F0M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

935293:PL78 RS14265
gene id: 935293:PL78_RS14265
uniprot id: A0A3S6F2Y8
names: Similarity
messages: Belongs to the SfsA family.

935293:PL78 RS08170
gene id: 935293:PL78_RS08170
uniprot id: A0A3S6EZA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS04110
gene id: 935293:PL78_RS04110
uniprot id: A0A3S6EX21
names: Similarity
messages: Belongs to the SIP oxidoreductase family.

935293:PL78 RS13415
gene id: 935293:PL78_RS13415
uniprot id: A0A3S6F253
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS15865
gene id: 935293:PL78_RS15865
uniprot id: A0A3S6F3U8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

935293:PL78 RS07960
gene id: 935293:PL78_RS07960
uniprot id: A0A3S6F0P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

935293:PL78 RS07375
gene id: 935293:PL78_RS07375
uniprot id: A0A3S6EZX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatase IpgD/SopB family.
messages: Secreted

935293:PL78 RS17615
gene id: 935293:PL78_RS17615
uniprot id: A0A3S6F4G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

935293:PL78 RS07190
gene id: 935293:PL78_RS07190
uniprot id: A0A3S6EZ68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import. Binds G3P.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

935293:PL78 RS17715
gene id: 935293:PL78_RS17715
uniprot id: A0A3S6F4I1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

935293:PL78 RS00310
gene id: 935293:PL78_RS00310
uniprot id: A0A3S6EUU4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

935293:PL78 RS14165
gene id: 935293:PL78_RS14165
uniprot id: A0A3S6F2W8
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

935293:PL78 RS17595
gene id: 935293:PL78_RS17595
uniprot id: A0A3S6F4T9
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

935293:PL78 RS13800
gene id: 935293:PL78_RS13800
uniprot id: A0A3S6F3G1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

935293:PL78 RS02240
gene id: 935293:PL78_RS02240
uniprot id: A0A3S6EW02
names: Similarity
messages: Belongs to the UPF0053 family.

935293:PL78 RS13545
gene id: 935293:PL78_RS13545
uniprot id: A0A3S6F3B3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RsmC family.
messages: Cytoplasm
messages: Monomer.
messages: Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.

935293:PL78 RS09575
gene id: 935293:PL78_RS09575
uniprot id: A0A3S6F032
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

935293:PL78 RS14080
gene id: 935293:PL78_RS14080
uniprot id: A0A3S6F449
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

935293:PL78 RS17390
gene id: 935293:PL78_RS17390
uniprot id: A0A3S6F4T3
names: Subcellular Location Annotation
messages: Cytoplasm

935293:PL78 RS15545
gene id: 935293:PL78_RS15545
uniprot id: A0A3S6F4D8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

935293:PL78 RS01495
gene id: 935293:PL78_RS01495
uniprot id: A0A3S6EVK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

935293:PL78 RS02795
gene id: 935293:PL78_RS02795
uniprot id: A0A3S6EWC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapC family.
messages: Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
messages: Cytoplasm
messages: Interacts directly with FtsZ.

935293:PL78 RS15950
gene id: 935293:PL78_RS15950
uniprot id: A0A3S6F4L8
names: Similarity
messages: Belongs to the acetyltransferase family. YpeA subfamily.

935293:PL78 RS08850
gene id: 935293:PL78_RS08850
uniprot id: A0A3S6F174
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

935293:PL78 RS05130
gene id: 935293:PL78_RS05130
uniprot id: A0A3S6EXM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

935293:PL78 RS07080
gene id: 935293:PL78_RS07080
uniprot id: A0A3S6EYR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

935293:PL78 RS12555
gene id: 935293:PL78_RS12555
uniprot id: A0A3S6F3A7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

935293:PL78 RS08980
gene id: 935293:PL78_RS08980
uniprot id: A0A3S6EZZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

935293:PL78 RS04750
gene id: 935293:PL78_RS04750
uniprot id: A0A3S6EYH6
names: Similarity
messages: Belongs to the peptidase S49 family.

935293:PL78 RS12450
gene id: 935293:PL78_RS12450
uniprot id: A0A3S6F225
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

935293:PL78 RS02375
gene id: 935293:PL78_RS02375
uniprot id: A0A3S6EW20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

935293:PL78 RS08405
gene id: 935293:PL78_RS08405
uniprot id: A0A3S6EZC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily.
messages: Cell inner membrane
messages: Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system).
messages: Membrane

935293:PL78 RS16355
gene id: 935293:PL78_RS16355
uniprot id: A0A3S6F442
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

935293:PL78 RS16730
gene id: 935293:PL78_RS16730
uniprot id: A0A3S6F427
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

935293:PL78 RS07285
gene id: 935293:PL78_RS07285
uniprot id: A0A3S6EZ11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

935293:PL78 RS08890
gene id: 935293:PL78_RS08890
uniprot id: A0A3S6EZM5
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

935293:PL78 RS04520
gene id: 935293:PL78_RS04520
uniprot id: A0A3S6EXA4
names: Similarity
names: Subunit
messages: Belongs to the KHG/KDPG aldolase family.
messages: Homotrimer.

935293:PL78 RS16845
gene id: 935293:PL78_RS16845
uniprot id: A0A3S6F476
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

935293:PL78 RS06930
gene id: 935293:PL78_RS06930
uniprot id: A0A3S6EZP5
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

935293:PL78 RS12535
gene id: 935293:PL78_RS12535
uniprot id: A0A3S6F1X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions.

935293:PL78 RS12395
gene id: 935293:PL78_RS12395
uniprot id: A0A3S6F1L3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: Homodimer. Forms homomultimers of about 100-150 subunits at optimal growth temperatures. Conformation changes to oligomers at high temperatures or high ionic concentrations. The decrease in size of the multimers is accompanied by an increase in chaperone activity.
messages: The N- and C-terminal flexible termini are involved in oligomerization and in the binding of non-native substrate proteins, and are essential for chaperone activity.

935293:PL78 RS02395
gene id: 935293:PL78_RS02395
uniprot id: A0A3S6EW38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.
messages: Cell membrane

935293:PL78 RS18910
gene id: 935293:PL78_RS18910
uniprot id: A0A3S6F5B9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

935293:PL78 RS01185
gene id: 935293:PL78_RS01185
uniprot id: A0A3S6EVF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

935293:PL78 RS09555
gene id: 935293:PL78_RS09555
uniprot id: A0A3S6F0E6
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

935293:PL78 RS11930
gene id: 935293:PL78_RS11930
uniprot id: A0A3S6F1Q8
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

935293:PL78 RS04505
gene id: 935293:PL78_RS04505
uniprot id: A0A3S6EXA2
names: Similarity
messages: Belongs to the pyruvate kinase family.

935293:PL78 RS01770
gene id: 935293:PL78_RS01770
uniprot id: A0A3S6EVP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

935293:PL78 RS17800
gene id: 935293:PL78_RS17800
uniprot id: A0A3S6F4M2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

935293:PL78 RS10850
gene id: 935293:PL78_RS10850
uniprot id: A0A3S6F162
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

935293:PL78 RS05705
gene id: 935293:PL78_RS05705
uniprot id: A0A3S6EXY8
names: Similarity
messages: Belongs to the PspA/IM30 family.

935293:PL78 RS04490
gene id: 935293:PL78_RS04490
uniprot id: A0A3S6EXB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 9 family.
messages: Periplasm

935293:PL78 RS14355
gene id: 935293:PL78_RS14355
uniprot id: A0A3S6F2U2
names: Subcellular Location Annotation
messages: Cell inner membrane

935293:PL78 RS17865
gene id: 935293:PL78_RS17865
uniprot id: A0A3S6F4L1
names: Function
names: Similarity
messages: Belongs to the EfeM/EfeO family.
messages: Involved in Fe(2+) uptake. Could be an iron-binding and/or electron-transfer component.

935293:PL78 RS16375
gene id: 935293:PL78_RS16375
uniprot id: A0A3S6F3R6
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

935293:PL78 RS16030
gene id: 935293:PL78_RS16030
uniprot id: A0A3S6F578
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

935293:PL78 RS08750
gene id: 935293:PL78_RS08750
uniprot id: A0A3S6EZM7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS12255
gene id: 935293:PL78_RS12255
uniprot id: A0A3S6F354
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

935293:PL78 RS09460
gene id: 935293:PL78_RS09460
uniprot id: A0A3S6F1K0
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

935293:PL78 RS00430
gene id: 935293:PL78_RS00430
uniprot id: A0A3S6EVG0
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS09455
gene id: 935293:PL78_RS09455
uniprot id: A0A3S6F0C7
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

935293:PL78 RS11630
gene id: 935293:PL78_RS11630
uniprot id: A0A3S6F1E5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

935293:PL78 RS14575
gene id: 935293:PL78_RS14575
uniprot id: A0A3S6F4E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS08555
gene id: 935293:PL78_RS08555
uniprot id: A0A3S6F0J1
names: Similarity
messages: Belongs to the UPF0253 family.

935293:PL78 RS11290
gene id: 935293:PL78_RS11290
uniprot id: A0A3S6F0Z3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

935293:PL78 RS11635
gene id: 935293:PL78_RS11635
uniprot id: A0A3S6F1K2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

935293:PL78 RS10800
gene id: 935293:PL78_RS10800
uniprot id: A0A3S6F151
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

935293:PL78 RS14630
gene id: 935293:PL78_RS14630
uniprot id: A0A3S6F2U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SctE/SipB/YopB family.
messages: Host membrane

935293:PL78 RS00385
gene id: 935293:PL78_RS00385
uniprot id: A0A3S6EUW4
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

935293:PL78 RS05940
gene id: 935293:PL78_RS05940
uniprot id: A0A3S6EY17
names: Domain
names: Function
names: Subunit
messages: Consists of two structural and functional domains: an N-terminal DNA-binding domain, approximately the first 60 residues, and a larger C-terminal domain, approximately 280 residues, which imparts the function of corepressor binding and oligomerization.
messages: Homodimer.
messages: Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.

935293:PL78 RS10555
gene id: 935293:PL78_RS10555
uniprot id: A0A3S6F0K5
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

935293:PL78 RS16110
gene id: 935293:PL78_RS16110
uniprot id: A0A3S6F3R4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

935293:PL78 RS06040
gene id: 935293:PL78_RS06040
uniprot id: A0A3S6EY72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

935293:PL78 RS16840
gene id: 935293:PL78_RS16840
uniprot id: A0A3S6F544
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

935293:PL78 RS01100
gene id: 935293:PL78_RS01100
uniprot id: A0A3S6EVB8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

935293:PL78 RS13890
gene id: 935293:PL78_RS13890
uniprot id: A0A3S6F2G7
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

935293:PL78 RS05165
gene id: 935293:PL78_RS05165
uniprot id: A0A3S6EXN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS10395
gene id: 935293:PL78_RS10395
uniprot id: A0A3S6F0S7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SIS family. DiaA subfamily.
messages: Homotetramer; dimer of dimers.
messages: Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein.

935293:PL78 RS06165
gene id: 935293:PL78_RS06165
uniprot id: A0A3S6EYJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).

935293:PL78 RS17110
gene id: 935293:PL78_RS17110
uniprot id: A0A3S6F4C6
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS05510
gene id: 935293:PL78_RS05510
uniprot id: A0A3S6EXW3
names: Subcellular Location Annotation
messages: Cell inner membrane

935293:PL78 RS12050
gene id: 935293:PL78_RS12050
uniprot id: A0A3S6F1E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS08615
gene id: 935293:PL78_RS08615
uniprot id: A0A3S6EZS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

935293:PL78 RS05245
gene id: 935293:PL78_RS05245
uniprot id: A0A3S6EZB6
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS07720
gene id: 935293:PL78_RS07720
uniprot id: A0A3S6EZ14
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer.

935293:PL78 RS01475
gene id: 935293:PL78_RS01475
uniprot id: A0A3S6EW19
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

935293:PL78 RS02220
gene id: 935293:PL78_RS02220
uniprot id: A0A3S6EWG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

935293:PL78 RS18550
gene id: 935293:PL78_RS18550
uniprot id: A0A3S6F6U6
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS18590
gene id: 935293:PL78_RS18590
uniprot id: A0A3S6F523
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

935293:PL78 RS04375
gene id: 935293:PL78_RS04375
uniprot id: A0A3S6EX72
names: Similarity
messages: Belongs to the UPF0502 family.

935293:PL78 RS02000
gene id: 935293:PL78_RS02000
uniprot id: A0A3S6EVW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

935293:PL78 RS07565
gene id: 935293:PL78_RS07565
uniprot id: A0A3S6EYX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WzzB/Cld/Rol family.
messages: Cell inner membrane
messages: Membrane
messages: Modulates the polysaccharide chain length of enterobacterial common antigen (ECA).
messages: Probably part of a complex composed of WzxE, WzyE and WzzE.

935293:PL78 RS17855
gene id: 935293:PL78_RS17855
uniprot id: A0A3S6F527
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

935293:PL78 RS17590
gene id: 935293:PL78_RS17590
uniprot id: A0A3S6F4P2
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

935293:PL78 RS06620
gene id: 935293:PL78_RS06620
uniprot id: A0A3S6EYE8
names: Function
names: Similarity
messages: Belongs to the FrsA family.
messages: Catalyzes the hydrolysis of esters.

935293:PL78 RS17645
gene id: 935293:PL78_RS17645
uniprot id: A0A3S6F4V3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

935293:PL78 RS02175
gene id: 935293:PL78_RS02175
uniprot id: A0A3S6EVX9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion.
messages: Homodimer.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

935293:PL78 RS10245
gene id: 935293:PL78_RS10245
uniprot id: A0A3S6F0U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IgaA family.
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS10695
gene id: 935293:PL78_RS10695
uniprot id: A0A3S6F0X7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

935293:PL78 RS17515
gene id: 935293:PL78_RS17515
uniprot id: A0A3S6F4E1
names: Subcellular Location Annotation
messages: Cytoplasm

935293:PL78 RS08435
gene id: 935293:PL78_RS08435
uniprot id: A0A3S6F0H5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

935293:PL78 RS15910
gene id: 935293:PL78_RS15910
uniprot id: A0A3S6F3S1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudK subfamily.
messages: Homodimer.
messages: Nucleoside diphosphate sugar hydrolase that hydrolyzes GDP-mannose as its preferred substrate, yielding GMP and mannose-1-phosphate.

935293:PL78 RS00745
gene id: 935293:PL78_RS00745
uniprot id: A0A3S6EV44
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

935293:PL78 RS06000
gene id: 935293:PL78_RS06000
uniprot id: A0A3S6EYJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SufE family.
messages: Cytoplasm
messages: Homodimer. Interacts with SufS.
messages: Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process.

935293:PL78 RS02765
gene id: 935293:PL78_RS02765
uniprot id: A0A3S6EWI1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

935293:PL78 RS02235
gene id: 935293:PL78_RS02235
uniprot id: A0A3S6EXM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
messages: Membrane

935293:PL78 RS11490
gene id: 935293:PL78_RS11490
uniprot id: A0A3S6F132
names: Similarity
messages: Belongs to the UPF0270 family.

935293:PL78 RS15305
gene id: 935293:PL78_RS15305
uniprot id: A0A3S6F3F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

935293:PL78 RS07370
gene id: 935293:PL78_RS07370
uniprot id: A0A3S6EYW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IpgE/SigE chaperone family.
messages: Cytoplasm

935293:PL78 RS14070
gene id: 935293:PL78_RS14070
uniprot id: A0A3S6F2H9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

935293:PL78 RS14455
gene id: 935293:PL78_RS14455
uniprot id: A0A3S6F301
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS08735
gene id: 935293:PL78_RS08735
uniprot id: A0A3S6F154
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Xni family.
messages: Binds 1 K(+) per subunit. The potassium ion strongly increases the affinity for DNA.
messages: Binds 2 Mg(2+) per subunit. Only one magnesium ion has a direct interaction with the protein, the other interactions are indirect.
messages: Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.

935293:PL78 RS13830
gene id: 935293:PL78_RS13830
uniprot id: A0A3S6F3Z7
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

935293:PL78 RS09930
gene id: 935293:PL78_RS09930
uniprot id: A0A3S6F0B3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

935293:PL78 RS09535
gene id: 935293:PL78_RS09535
uniprot id: A0A3S6F044
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

935293:PL78 RS14925
gene id: 935293:PL78_RS14925
uniprot id: A0A3S6F2Z8
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS09095
gene id: 935293:PL78_RS09095
uniprot id: A0A3S6EZR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

935293:PL78 RS11595
gene id: 935293:PL78_RS11595
uniprot id: A0A3S6F1K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

935293:PL78 RS01455
gene id: 935293:PL78_RS01455
uniprot id: A0A3S6EVK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth.

935293:PL78 RS18190
gene id: 935293:PL78_RS18190
uniprot id: A0A3S6F5Z0
names: Similarity
messages: Belongs to the LcrH/SycD chaperone family.

935293:PL78 RS14110
gene id: 935293:PL78_RS14110
uniprot id: A0A3S6F2S9
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

935293:PL78 RS17125
gene id: 935293:PL78_RS17125
uniprot id: A0A3S6F492
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxT phosphotransferase family.
messages: Cell inner membrane
messages: Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1-diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P).

935293:PL78 RS03245
gene id: 935293:PL78_RS03245
uniprot id: A0A3S6EWK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

935293:PL78 RS05855
gene id: 935293:PL78_RS05855
uniprot id: A0A3S6EY15
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

935293:PL78 RS15605
gene id: 935293:PL78_RS15605
uniprot id: A0A3S6F3L5
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

935293:PL78 RS05290
gene id: 935293:PL78_RS05290
uniprot id: A0A3S6EY22
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

935293:PL78 RS18365
gene id: 935293:PL78_RS18365
uniprot id: A0A3S6F5B5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

935293:PL78 RS13590
gene id: 935293:PL78_RS13590
uniprot id: A0A3S6F296
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

935293:PL78 RS15395
gene id: 935293:PL78_RS15395
uniprot id: A0A3S6F4A7
names: Similarity
messages: Belongs to the P(II) protein family.

935293:PL78 RS15210
gene id: 935293:PL78_RS15210
uniprot id: A0A3S6F3G5
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

935293:PL78 RS03305
gene id: 935293:PL78_RS03305
uniprot id: A0A3S6EWN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs.
messages: Cytoplasm
messages: Interacts with TusE.

935293:PL78 RS14310
gene id: 935293:PL78_RS14310
uniprot id: A0A3S6F2X2
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS00790
gene id: 935293:PL78_RS00790
uniprot id: A0A3S6EVN4
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

935293:PL78 RS00345
gene id: 935293:PL78_RS00345
uniprot id: A0A3S6EWL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

935293:PL78 RS06140
gene id: 935293:PL78_RS06140
uniprot id: A0A3S6EZ94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
messages: Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Homodimer.

935293:PL78 RS08520
gene id: 935293:PL78_RS08520
uniprot id: A0A3S6EZV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

935293:PL78 RS13995
gene id: 935293:PL78_RS13995
uniprot id: A0A3S6F2K8
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS08460
gene id: 935293:PL78_RS08460
uniprot id: A0A3S6EZT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS10320
gene id: 935293:PL78_RS10320
uniprot id: A0A3S6F0I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS16000
gene id: 935293:PL78_RS16000
uniprot id: A0A3S6F4M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

935293:PL78 RS06745
gene id: 935293:PL78_RS06745
uniprot id: A0A3S6EYJ8
names: Function
names: Subunit
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.
messages: The DNA polymerase holoenzyme is a complex that contains 10 different types of subunits. These subunits are organized into 3 functionally essential subassemblies: the pol III core, the beta sliding clamp processivity factor and the clamp-loading complex. The pol III core (subunits alpha,epsilon and theta) contains the polymerase and the 3'-5' exonuclease proofreading activities. The polymerase is tethered to the template via the sliding clamp processivity factor. The clamp-loading complex assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork. This complex contains delta, delta', psi and chi, and copies of either or both of two different DnaX proteins, gamma and tau.

935293:PL78 RS04340
gene id: 935293:PL78_RS04340
uniprot id: A0A3S6EX71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrA subfamily.
messages: Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
messages: Cytoplasm

935293:PL78 RS18080
gene id: 935293:PL78_RS18080
uniprot id: A0A3S6F4U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YdjC deacetylase family. ChbG subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the degradation of chitin. ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose. Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF. Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the inducer of ChbR and the substrate of ChbF.

935293:PL78 RS05600
gene id: 935293:PL78_RS05600
uniprot id: A0A3S6EZH0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

935293:PL78 RS04150
gene id: 935293:PL78_RS04150
uniprot id: A0A3S6EX37
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. AstD subfamily.
messages: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.

935293:PL78 RS15410
gene id: 935293:PL78_RS15410
uniprot id: A0A3S6F3K9
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS11340
gene id: 935293:PL78_RS11340
uniprot id: A0A3S6F104
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

935293:PL78 RS07765
gene id: 935293:PL78_RS07765
uniprot id: A0A3S6EZ09
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS10610
gene id: 935293:PL78_RS10610
uniprot id: A0A3S6F117
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.
messages: Membrane

935293:PL78 RS16335
gene id: 935293:PL78_RS16335
uniprot id: A0A3S6F3V6
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS05655
gene id: 935293:PL78_RS05655
uniprot id: A0A3S6EXY3
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

935293:PL78 RS14360
gene id: 935293:PL78_RS14360
uniprot id: A0A3S6F2Y3
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

935293:PL78 RS02660
gene id: 935293:PL78_RS02660
uniprot id: A0A3S6EW95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

935293:PL78 RS18565
gene id: 935293:PL78_RS18565
uniprot id: A0A3S6F550
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

935293:PL78 RS13515
gene id: 935293:PL78_RS13515
uniprot id: A0A3S6F273
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

935293:PL78 RS14725
gene id: 935293:PL78_RS14725
uniprot id: A0A3S6F351
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

935293:PL78 RS18170
gene id: 935293:PL78_RS18170
uniprot id: A0A3S6F6H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS01615
gene id: 935293:PL78_RS01615
uniprot id: A0A3S6EW42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

935293:PL78 RS14675
gene id: 935293:PL78_RS14675
uniprot id: A0A3S6F4G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

935293:PL78 RS06830
gene id: 935293:PL78_RS06830
uniprot id: A0A3S6EZM4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

935293:PL78 RS10845
gene id: 935293:PL78_RS10845
uniprot id: A0A3S6F105
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

935293:PL78 RS16745
gene id: 935293:PL78_RS16745
uniprot id: A0A3S6F455
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

935293:PL78 RS13975
gene id: 935293:PL78_RS13975
uniprot id: A0A3S6F2W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster. Acts by binding directly to DNA. May also regulate the expression of genes outside the dcw cluster.
messages: nucleoid

935293:PL78 RS09075
gene id: 935293:PL78_RS09075
uniprot id: A0A3S6F0U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

935293:PL78 RS16640
gene id: 935293:PL78_RS16640
uniprot id: A0A3S6F4Z8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

935293:PL78 RS01530
gene id: 935293:PL78_RS01530
uniprot id: A0A3S6EVK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

935293:PL78 RS09680
gene id: 935293:PL78_RS09680
uniprot id: A0A3S6F061
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

935293:PL78 RS04575
gene id: 935293:PL78_RS04575
uniprot id: A0A3S6EXP3
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

935293:PL78 RS11615
gene id: 935293:PL78_RS11615
uniprot id: A0A3S6F1A3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

935293:PL78 RS17835
gene id: 935293:PL78_RS17835
uniprot id: A0A3S6F4Q4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

935293:PL78 RS14805
gene id: 935293:PL78_RS14805
uniprot id: A0A3S6F302
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

935293:PL78 RS01940
gene id: 935293:PL78_RS01940
uniprot id: A0A3S6EVU1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Membrane

935293:PL78 RS02590
gene id: 935293:PL78_RS02590
uniprot id: A0A3S6EW74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

935293:PL78 RS02550
gene id: 935293:PL78_RS02550
uniprot id: A0A3S6EW78
names: Similarity
messages: Belongs to the ClpA/ClpB family.

935293:PL78 RS17655
gene id: 935293:PL78_RS17655
uniprot id: A0A3S6F4Y3
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

935293:PL78 RS01585
gene id: 935293:PL78_RS01585
uniprot id: A0A3S6EVL6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

935293:PL78 RS04460
gene id: 935293:PL78_RS04460
uniprot id: A0A3S6EXF7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

935293:PL78 RS06655
gene id: 935293:PL78_RS06655
uniprot id: A0A3S6EYJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

935293:PL78 RS01115
gene id: 935293:PL78_RS01115
uniprot id: A0A3S6EVD1
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

935293:PL78 RS15730
gene id: 935293:PL78_RS15730
uniprot id: A0A3S6F521
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS13330
gene id: 935293:PL78_RS13330
uniprot id: A0A3S6F297
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

935293:PL78 RS00815
gene id: 935293:PL78_RS00815
uniprot id: A0A3S6EV58
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS13600
gene id: 935293:PL78_RS13600
uniprot id: A0A3S6F3C4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

935293:PL78 RS11245
gene id: 935293:PL78_RS11245
uniprot id: A0A3S6F1D9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

935293:PL78 RS11300
gene id: 935293:PL78_RS11300
uniprot id: A0A3S6F2M3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

935293:PL78 RS04075
gene id: 935293:PL78_RS04075
uniprot id: A0A3S6EX22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS18720
gene id: 935293:PL78_RS18720
uniprot id: A0A3S6F6A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopD family.
messages: Cell inner membrane
messages: Involved in copper resistance.
messages: Membrane

935293:PL78 RS00525
gene id: 935293:PL78_RS00525
uniprot id: A0A3S6EV85
names: Similarity
messages: Belongs to the P(II) protein family.

935293:PL78 RS12480
gene id: 935293:PL78_RS12480
uniprot id: A0A3S6F1S3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

935293:PL78 RS00670
gene id: 935293:PL78_RS00670
uniprot id: A0A3S6EV35
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

935293:PL78 RS01450
gene id: 935293:PL78_RS01450
uniprot id: A0A3S6EVJ1
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: The heme is bound between the two transmembrane subunits.

935293:PL78 RS07065
gene id: 935293:PL78_RS07065
uniprot id: A0A3S6EYP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RfaH family.
messages: Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons. Once bound, RfaH suppresses pausing and inhibits Rho-dependent and intrinsic termination at a subset of sites. Termination signals are bypassed, which allows complete synthesis of long RNA chains.
messages: Interacts with both the nontemplate DNA and the RNA polymerase (RNAP).

935293:PL78 RS03065
gene id: 935293:PL78_RS03065
uniprot id: A0A3S6EWH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

935293:PL78 RS06125
gene id: 935293:PL78_RS06125
uniprot id: A0A3S6EY65
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
messages: Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

935293:PL78 RS14685
gene id: 935293:PL78_RS14685
uniprot id: A0A3S6F2Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

935293:PL78 RS16010
gene id: 935293:PL78_RS16010
uniprot id: A0A3S6F3U3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

935293:PL78 RS05675
gene id: 935293:PL78_RS05675
uniprot id: A0A3S6EY01
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

935293:PL78 RS04820
gene id: 935293:PL78_RS04820
uniprot id: A0A3S6EXN0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

935293:PL78 RS06365
gene id: 935293:PL78_RS06365
uniprot id: A0A3S6EYN0
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

935293:PL78 RS15755
gene id: 935293:PL78_RS15755
uniprot id: A0A3S6F3L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

935293:PL78 RS13780
gene id: 935293:PL78_RS13780
uniprot id: A0A3S6F3Y6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

935293:PL78 RS08680
gene id: 935293:PL78_RS08680
uniprot id: A0A3S6EZX3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

935293:PL78 RS12595
gene id: 935293:PL78_RS12595
uniprot id: A0A3S6F1Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

935293:PL78 RS14745
gene id: 935293:PL78_RS14745
uniprot id: A0A3S6F4H6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

935293:PL78 RS09510
gene id: 935293:PL78_RS09510
uniprot id: A0A3S6F1L0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

935293:PL78 RS14210
gene id: 935293:PL78_RS14210
uniprot id: A0A3S6F2U8
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

935293:PL78 RS04860
gene id: 935293:PL78_RS04860
uniprot id: A0A3S6EYJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS07110
gene id: 935293:PL78_RS07110
uniprot id: A0A3S6EYP3
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

935293:PL78 RS09490
gene id: 935293:PL78_RS09490
uniprot id: A0A3S6F099
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

935293:PL78 RS10805
gene id: 935293:PL78_RS10805
uniprot id: A0A3S6F0Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

935293:PL78 RS04830
gene id: 935293:PL78_RS04830
uniprot id: A0A3S6EXG6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

935293:PL78 RS09645
gene id: 935293:PL78_RS09645
uniprot id: A0A3S6F0C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

935293:PL78 RS12475
gene id: 935293:PL78_RS12475
uniprot id: A0A3S6F2R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

935293:PL78 RS11830
gene id: 935293:PL78_RS11830
uniprot id: A0A3S6F1I6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

935293:PL78 RS04480
gene id: 935293:PL78_RS04480
uniprot id: A0A3S6EYW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS13430
gene id: 935293:PL78_RS13430
uniprot id: A0A3S6F392
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

935293:PL78 RS03060
gene id: 935293:PL78_RS03060
uniprot id: A0A3S6EXJ0
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

935293:PL78 RS11520
gene id: 935293:PL78_RS11520
uniprot id: A0A3S6F271
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in both the arginine and lysine biosynthetic pathways.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS09400
gene id: 935293:PL78_RS09400
uniprot id: A0A3S6EZX5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

935293:PL78 RS13095
gene id: 935293:PL78_RS13095
uniprot id: A0A3S6F1Z6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

935293:PL78 RS15820
gene id: 935293:PL78_RS15820
uniprot id: A0A3S6F3I3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS16750
gene id: 935293:PL78_RS16750
uniprot id: A0A3S6F479
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS06710
gene id: 935293:PL78_RS06710
uniprot id: A0A3S6EYQ2
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

935293:PL78 RS00395
gene id: 935293:PL78_RS00395
uniprot id: A0A3S6EWM5
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS00315
gene id: 935293:PL78_RS00315
uniprot id: A0A3S6EW16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

935293:PL78 RS11360
gene id: 935293:PL78_RS11360
uniprot id: A0A3S6F125
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

935293:PL78 RS13645
gene id: 935293:PL78_RS13645
uniprot id: A0A3S6F2E3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

935293:PL78 RS06625
gene id: 935293:PL78_RS06625
uniprot id: A0A3S6EYS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
messages: Cell membrane
messages: Homotetramer.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.

935293:PL78 RS14900
gene id: 935293:PL78_RS14900
uniprot id: A0A3S6F383
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

935293:PL78 RS11415
gene id: 935293:PL78_RS11415
uniprot id: A0A3S6F159
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

935293:PL78 RS01870
gene id: 935293:PL78_RS01870
uniprot id: A0A3S6EVR3
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

935293:PL78 RS02190
gene id: 935293:PL78_RS02190
uniprot id: A0A3S6EVZ2
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS10685
gene id: 935293:PL78_RS10685
uniprot id: A0A3S6F1R0
names: Similarity
messages: Belongs to the barstar family.

935293:PL78 RS18960
gene id: 935293:PL78_RS18960
uniprot id: A0A3S6F5C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

935293:PL78 RS16835
gene id: 935293:PL78_RS16835
uniprot id: A0A3S6F465
names: Function
names: Similarity
messages: Belongs to the isochorismate synthase family.
messages: Catalyzes the conversion of chorismate to isochorismate.

935293:PL78 RS13355
gene id: 935293:PL78_RS13355
uniprot id: A0A3S6F3R1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

935293:PL78 RS07950
gene id: 935293:PL78_RS07950
uniprot id: A0A3S6EZ43
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

935293:PL78 RS12855
gene id: 935293:PL78_RS12855
uniprot id: A0A3S6F1Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

935293:PL78 RS16435
gene id: 935293:PL78_RS16435
uniprot id: A0A3S6F3Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS08470
gene id: 935293:PL78_RS08470
uniprot id: A0A3S6EZE5
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt. Acetylates CheY, the response regulator involved in flagellar movement and chemotaxis.

935293:PL78 RS11600
gene id: 935293:PL78_RS11600
uniprot id: A0A3S6F2T5
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

935293:PL78 RS16180
gene id: 935293:PL78_RS16180
uniprot id: A0A3S6F3S3
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS07510
gene id: 935293:PL78_RS07510
uniprot id: A0A3S6EZD0
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS01180
gene id: 935293:PL78_RS01180
uniprot id: A0A3S6EWI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

935293:PL78 RS12225
gene id: 935293:PL78_RS12225
uniprot id: A0A3S6F2L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhE family.
messages: Cytoplasm
messages: Necessary for formate dehydrogenase activity.

935293:PL78 RS07930
gene id: 935293:PL78_RS07930
uniprot id: A0A3S6F071
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

935293:PL78 RS09125
gene id: 935293:PL78_RS09125
uniprot id: A0A3S6F0V6
names: Similarity
messages: Belongs to the UPF0149 family.

935293:PL78 RS02770
gene id: 935293:PL78_RS02770
uniprot id: A0A3S6EWS5
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

935293:PL78 RS09035
gene id: 935293:PL78_RS09035
uniprot id: A0A3S6F005
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD, in which XerC interacts with XerD via its C-terminal region, XerD interacts with XerC via its C-terminal region and so on.
messages: FtsK may regulate the catalytic switch between XerC and XerD in the heterotetrameric complex during the two steps of the recombination process.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerD specifically exchanges the bottom DNA strands.

935293:PL78 RS07400
gene id: 935293:PL78_RS07400
uniprot id: A0A3S6EZ71
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

935293:PL78 RS16950
gene id: 935293:PL78_RS16950
uniprot id: A0A3S6F4C0
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS16400
gene id: 935293:PL78_RS16400
uniprot id: A0A3S6F410
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).

935293:PL78 RS08975
gene id: 935293:PL78_RS08975
uniprot id: A0A3S6EZT1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane
messages: Type II secretion system is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus. Forms homomultimers.

935293:PL78 RS02600
gene id: 935293:PL78_RS02600
uniprot id: A0A3S6EW88
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS08165
gene id: 935293:PL78_RS08165
uniprot id: A0A3S6EZ91
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

935293:PL78 RS02545
gene id: 935293:PL78_RS02545
uniprot id: A0A3S6EW70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

935293:PL78 RS17045
gene id: 935293:PL78_RS17045
uniprot id: A0A3S6F490
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: To H.influenzae HI_0842.

935293:PL78 RS11690
gene id: 935293:PL78_RS11690
uniprot id: A0A3S6F173
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

935293:PL78 RS08635
gene id: 935293:PL78_RS08635
uniprot id: A0A3S6F134
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.

935293:PL78 RS16465
gene id: 935293:PL78_RS16465
uniprot id: A0A3S6F494
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

935293:PL78 RS02225
gene id: 935293:PL78_RS02225
uniprot id: A0A3S6EVZ0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS04855
gene id: 935293:PL78_RS04855
uniprot id: A0A3S6EXG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS03875
gene id: 935293:PL78_RS03875
uniprot id: A0A3S6EWZ2
names: Similarity
messages: Belongs to the autoinducer synthase family.

935293:PL78 RS08605
gene id: 935293:PL78_RS08605
uniprot id: A0A3S6F0K3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

935293:PL78 RS03995
gene id: 935293:PL78_RS03995
uniprot id: A0A3S6EX70
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10B family.
messages: Binds 1 zinc ion per subunit.

935293:PL78 RS09520
gene id: 935293:PL78_RS09520
uniprot id: A0A3S6F022
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

935293:PL78 RS01760
gene id: 935293:PL78_RS01760
uniprot id: A0A3S6EVX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

935293:PL78 RS06605
gene id: 935293:PL78_RS06605
uniprot id: A0A3S6EYI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

935293:PL78 RS17545
gene id: 935293:PL78_RS17545
uniprot id: A0A3S6F4S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

935293:PL78 RS16020
gene id: 935293:PL78_RS16020
uniprot id: A0A3S6F3M7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

935293:PL78 RS18605
gene id: 935293:PL78_RS18605
uniprot id: A0A3S6F503
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0266 family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS14430
gene id: 935293:PL78_RS14430
uniprot id: A0A3S6F2P7
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

935293:PL78 RS06520
gene id: 935293:PL78_RS06520
uniprot id: A0A3S6EYC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

935293:PL78 RS15980
gene id: 935293:PL78_RS15980
uniprot id: A0A3S6F571
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ROK (NagC/XylR) family. NanK subfamily.
messages: Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P.
messages: Homodimer.

935293:PL78 RS05680
gene id: 935293:PL78_RS05680
uniprot id: A0A3S6EY46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0283 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

935293:PL78 RS14345
gene id: 935293:PL78_RS14345
uniprot id: A0A3S6F2S7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dGTPase family. Type 1 subfamily.
messages: Homotetramer.
messages: dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs.

935293:PL78 RS12490
gene id: 935293:PL78_RS12490
uniprot id: A0A3S6F217
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

935293:PL78 RS03440
gene id: 935293:PL78_RS03440
uniprot id: A0A3S6EX29
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

935293:PL78 RS14005
gene id: 935293:PL78_RS14005
uniprot id: A0A3S6F2M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

935293:PL78 RS13005
gene id: 935293:PL78_RS13005
uniprot id: A0A3S6F223
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Homodimer.

935293:PL78 RS12440
gene id: 935293:PL78_RS12440
uniprot id: A0A3S6F206
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

935293:PL78 RS14780
gene id: 935293:PL78_RS14780
uniprot id: A0A3S6F379
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

935293:PL78 RS04140
gene id: 935293:PL78_RS04140
uniprot id: A0A3S6EX25
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in both the arginine and lysine biosynthetic pathways.

935293:PL78 RS08290
gene id: 935293:PL78_RS08290
uniprot id: A0A3S6EZL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS05955
gene id: 935293:PL78_RS05955
uniprot id: A0A3S6EY34
names: Similarity
messages: Belongs to the CFA/CMAS family.

935293:PL78 RS08620
gene id: 935293:PL78_RS08620
uniprot id: A0A3S6EZY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

935293:PL78 RS03610
gene id: 935293:PL78_RS03610
uniprot id: A0A3S6EWS4
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

935293:PL78 RS09690
gene id: 935293:PL78_RS09690
uniprot id: A0A3S6F073
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS07560
gene id: 935293:PL78_RS07560
uniprot id: A0A3S6EZE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
messages: Catalyzes the reversible epimerization at C-2 of UDP-N-acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues.
messages: Cytoplasm
messages: Homodimer.

935293:PL78 RS10515
gene id: 935293:PL78_RS10515
uniprot id: A0A3S6F268
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

935293:PL78 RS16530
gene id: 935293:PL78_RS16530
uniprot id: A0A3S6F3Y5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS07515
gene id: 935293:PL78_RS07515
uniprot id: A0A3S6EYW2
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family.
messages: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis.

935293:PL78 RS06185
gene id: 935293:PL78_RS06185
uniprot id: A0A3S6EY96
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

935293:PL78 RS15725
gene id: 935293:PL78_RS15725
uniprot id: A0A3S6F3V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

935293:PL78 RS05230
gene id: 935293:PL78_RS05230
uniprot id: A0A3S6EY52
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

935293:PL78 RS16665
gene id: 935293:PL78_RS16665
uniprot id: A0A3S6F4D9
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS11325
gene id: 935293:PL78_RS11325
uniprot id: A0A3S6F145
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

935293:PL78 RS12250
gene id: 935293:PL78_RS12250
uniprot id: A0A3S6F1Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

935293:PL78 RS15565
gene id: 935293:PL78_RS15565
uniprot id: A0A3S6F3D3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

935293:PL78 RS04935
gene id: 935293:PL78_RS04935
uniprot id: A0A3S6EXW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0259 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

935293:PL78 RS11100
gene id: 935293:PL78_RS11100
uniprot id: A0A3S6F1A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

935293:PL78 RS07540
gene id: 935293:PL78_RS07540
uniprot id: A0A3S6EYZ5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WecD family.
messages: Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino-4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS06600
gene id: 935293:PL78_RS06600
uniprot id: A0A3S6EZI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.
messages: Bacterial flagellum basal body
messages: Belongs to the YcgR family.
messages: Monomer. Interacts with the flagellar basal bodies.

935293:PL78 RS12805
gene id: 935293:PL78_RS12805
uniprot id: A0A3S6F1Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

935293:PL78 RS05765
gene id: 935293:PL78_RS05765
uniprot id: A0A3S6EY16
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS15230
gene id: 935293:PL78_RS15230
uniprot id: A0A3S6F356
names: Function
messages: Acts as a radical domain for damaged PFL and possibly other radical proteins.

935293:PL78 RS04160
gene id: 935293:PL78_RS04160
uniprot id: A0A3S6EXJ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Transforms N(2)-succinylglutamate into succinate and glutamate.

935293:PL78 RS11915
gene id: 935293:PL78_RS11915
uniprot id: A0A3S6F2F0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

935293:PL78 RS02810
gene id: 935293:PL78_RS02810
uniprot id: A0A3S6EWC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

935293:PL78 RS11780
gene id: 935293:PL78_RS11780
uniprot id: A0A3S6F1H5
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

935293:PL78 RS00680
gene id: 935293:PL78_RS00680
uniprot id: A0A3S6EV45
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

935293:PL78 RS11475
gene id: 935293:PL78_RS11475
uniprot id: A0A3S6F175
names: Similarity
messages: Belongs to the PhzF family.

935293:PL78 RS07820
gene id: 935293:PL78_RS07820
uniprot id: A0A3S6EZ35
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

935293:PL78 RS11745
gene id: 935293:PL78_RS11745
uniprot id: A0A3S6F1P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

935293:PL78 RS04475
gene id: 935293:PL78_RS04475
uniprot id: A0A3S6EXM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. DtpB subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Proton-dependent permease that transports di- and tripeptides.

935293:PL78 RS12680
gene id: 935293:PL78_RS12680
uniprot id: A0A3S6F1W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

935293:PL78 RS14955
gene id: 935293:PL78_RS14955
uniprot id: A0A3S6F3B4
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

935293:PL78 RS12735
gene id: 935293:PL78_RS12735
uniprot id: A0A3S6F1U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

935293:PL78 RS16595
gene id: 935293:PL78_RS16595
uniprot id: A0A3S6F426
names: Similarity
messages: Belongs to the GST superfamily.

935293:PL78 RS16715
gene id: 935293:PL78_RS16715
uniprot id: A0A3S6F4E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

935293:PL78 RS01705
gene id: 935293:PL78_RS01705
uniprot id: A0A3S6EVP6
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

935293:PL78 RS11920
gene id: 935293:PL78_RS11920
uniprot id: A0A3S6F1G7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

935293:PL78 RS07130
gene id: 935293:PL78_RS07130
uniprot id: A0A3S6EYS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine to uracil and ribose-1-phosphate.
messages: Cytoplasm

935293:PL78 RS18665
gene id: 935293:PL78_RS18665
uniprot id: A0A3S6F567
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DbpA subfamily.
messages: Contains an N-terminal domain that binds non-specifically to RNA and a C-terminal domain that binds specifically and tightly to hairpin 92 of 23S rRNA.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes.

935293:PL78 RS12090
gene id: 935293:PL78_RS12090
uniprot id: A0A3S6F1F1
names: Similarity
messages: Belongs to the OsmC/Ohr family.

935293:PL78 RS09550
gene id: 935293:PL78_RS09550
uniprot id: A0A3S6F006
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS10470
gene id: 935293:PL78_RS10470
uniprot id: A0A3S6F0H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

935293:PL78 RS08810
gene id: 935293:PL78_RS08810
uniprot id: A0A3S6EZM9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

935293:PL78 RS02030
gene id: 935293:PL78_RS02030
uniprot id: A0A3S6EWA5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

935293:PL78 RS03920
gene id: 935293:PL78_RS03920
uniprot id: A0A3S6EWY9
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS02260
gene id: 935293:PL78_RS02260
uniprot id: A0A3S6EW14
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

935293:PL78 RS12615
gene id: 935293:PL78_RS12615
uniprot id: A0A3S6F1S2
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS16825
gene id: 935293:PL78_RS16825
uniprot id: A0A3S6F411
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS15525
gene id: 935293:PL78_RS15525
uniprot id: A0A3S6F4Y1
names: Function
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.
messages: Protects the bacterial cell from host peptidases.

935293:PL78 RS02275
gene id: 935293:PL78_RS02275
uniprot id: A0A3S6EW00
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

935293:PL78 RS04580
gene id: 935293:PL78_RS04580
uniprot id: A0A3S6EYY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

935293:PL78 RS11995
gene id: 935293:PL78_RS11995
uniprot id: A0A3S6F312
names: Function
messages: Required for maximal bacterial cellulose synthesis.

935293:PL78 RS10960
gene id: 935293:PL78_RS10960
uniprot id: A0A3S6F187
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

935293:PL78 RS09865
gene id: 935293:PL78_RS09865
uniprot id: A0A3S6F1U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

935293:PL78 RS11350
gene id: 935293:PL78_RS11350
uniprot id: A0A3S6F2N3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

935293:PL78 RS16735
gene id: 935293:PL78_RS16735
uniprot id: A0A3S6F446
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS06820
gene id: 935293:PL78_RS06820
uniprot id: A0A3S6EYK6
names: Similarity
messages: Belongs to the GARS family.

935293:PL78 RS13940
gene id: 935293:PL78_RS13940
uniprot id: A0A3S6F2H7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

935293:PL78 RS11050
gene id: 935293:PL78_RS11050
uniprot id: A0A3S6F197
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

935293:PL78 RS17585
gene id: 935293:PL78_RS17585
uniprot id: A0A3S6F4K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS00785
gene id: 935293:PL78_RS00785
uniprot id: A0A3S6EVD8
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS16960
gene id: 935293:PL78_RS16960
uniprot id: A0A3S6F464
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Membrane

935293:PL78 RS01355
gene id: 935293:PL78_RS01355
uniprot id: A0A3S6EVI5
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS13675
gene id: 935293:PL78_RS13675
uniprot id: A0A3S6F2Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TrpR family.
messages: Cytoplasm
messages: Homodimer.
messages: This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.

935293:PL78 RS13455
gene id: 935293:PL78_RS13455
uniprot id: A0A3S6F2L0
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

935293:PL78 RS09530
gene id: 935293:PL78_RS09530
uniprot id: A0A3S6F129
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Monomer.

935293:PL78 RS13365
gene id: 935293:PL78_RS13365
uniprot id: A0A3S6F255
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

935293:PL78 RS12380
gene id: 935293:PL78_RS12380
uniprot id: A0A3S6F1Q2
names: Cofactor
messages: Binds 1 Ca(2+) ion per subunit.

935293:PL78 RS05115
gene id: 935293:PL78_RS05115
uniprot id: A0A3S6EXM3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

935293:PL78 RS04680
gene id: 935293:PL78_RS04680
uniprot id: A0A3S6EZ05
names: Similarity
messages: Belongs to the pirin family.

935293:PL78 RS00390
gene id: 935293:PL78_RS00390
uniprot id: A0A3S6EVC8
names: Similarity
messages: Belongs to the UPF0234 family.

935293:PL78 RS16850
gene id: 935293:PL78_RS16850
uniprot id: A0A3S6F498
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS09440
gene id: 935293:PL78_RS09440
uniprot id: A0A3S6F087
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

935293:PL78 RS09540
gene id: 935293:PL78_RS09540
uniprot id: A0A3S6F0A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
messages: Monomer.

935293:PL78 RS12110
gene id: 935293:PL78_RS12110
uniprot id: A0A3S6F1H3
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS09140
gene id: 935293:PL78_RS09140
uniprot id: A0A3S6F027
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

935293:PL78 RS01860
gene id: 935293:PL78_RS01860
uniprot id: A0A3S6EVZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

935293:PL78 RS06565
gene id: 935293:PL78_RS06565
uniprot id: A0A3S6EYW1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family. AroL subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.
messages: The LID domain closes over the active site upon ATP binding.

935293:PL78 RS14030
gene id: 935293:PL78_RS14030
uniprot id: A0A3S6F440
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

935293:PL78 RS16005
gene id: 935293:PL78_RS16005
uniprot id: A0A3S6F3R7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

935293:PL78 RS01910
gene id: 935293:PL78_RS01910
uniprot id: A0A3S6EW09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

935293:PL78 RS01665
gene id: 935293:PL78_RS01665
uniprot id: A0A3S6EW52
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

935293:PL78 RS04775
gene id: 935293:PL78_RS04775
uniprot id: A0A3S6EXT6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

935293:PL78 RS12800
gene id: 935293:PL78_RS12800
uniprot id: A0A3S6F1V2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

935293:PL78 RS15835
gene id: 935293:PL78_RS15835
uniprot id: A0A3S6F3G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0370 family.
messages: Cell membrane

935293:PL78 RS13865
gene id: 935293:PL78_RS13865
uniprot id: A0A3S6F2R2
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

935293:PL78 RS10350
gene id: 935293:PL78_RS10350
uniprot id: A0A3S6F0G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

935293:PL78 RS00285
gene id: 935293:PL78_RS00285
uniprot id: A0A3S6EUT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS00330
gene id: 935293:PL78_RS00330
uniprot id: A0A3S6EVD7
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

935293:PL78 RS07760
gene id: 935293:PL78_RS07760
uniprot id: A0A3S6F0K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

935293:PL78 RS16795
gene id: 935293:PL78_RS16795
uniprot id: A0A3S6F466
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS10360
gene id: 935293:PL78_RS10360
uniprot id: A0A3S6F239
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS09990
gene id: 935293:PL78_RS09990
uniprot id: A0A3S6F0J4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

935293:PL78 RS01220
gene id: 935293:PL78_RS01220
uniprot id: A0A3S6EVE8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

935293:PL78 RS11355
gene id: 935293:PL78_RS11355
uniprot id: A0A3S6F100
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

935293:PL78 RS13200
gene id: 935293:PL78_RS13200
uniprot id: A0A3S6F2G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Catalyzes both the uptake and excretion of putrescine. The uptake of putrescine is dependent on the membrane potential and the excretion involves putrescine-ornithine antiporter activity.
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS15595
gene id: 935293:PL78_RS15595
uniprot id: A0A3S6F4E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

935293:PL78 RS15650
gene id: 935293:PL78_RS15650
uniprot id: A0A3S6F4G0
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

935293:PL78 RS17680
gene id: 935293:PL78_RS17680
uniprot id: A0A3S6F5L0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

935293:PL78 RS16350
gene id: 935293:PL78_RS16350
uniprot id: A0A3S6F403
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

935293:PL78 RS18340
gene id: 935293:PL78_RS18340
uniprot id: A0A3S6F624
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS16420
gene id: 935293:PL78_RS16420
uniprot id: A0A3S6F5E5
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Methylates ribosomal protein uL3 on a specific glutamine residue.

935293:PL78 RS09950
gene id: 935293:PL78_RS09950
uniprot id: A0A3S6F088
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

935293:PL78 RS15570
gene id: 935293:PL78_RS15570
uniprot id: A0A3S6F3S8
names: Similarity
messages: Belongs to the YfgM family.

935293:PL78 RS06095
gene id: 935293:PL78_RS06095
uniprot id: A0A3S6EY82
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

935293:PL78 RS09940
gene id: 935293:PL78_RS09940
uniprot id: A0A3S6F0I9
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS13980
gene id: 935293:PL78_RS13980
uniprot id: A0A3S6F431
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

935293:PL78 RS04275
gene id: 935293:PL78_RS04275
uniprot id: A0A3S6EYS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

935293:PL78 RS15900
gene id: 935293:PL78_RS15900
uniprot id: A0A3S6F4K9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapB family.
messages: Binds 2 heme C groups per subunit.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Electron transfer subunit of the periplasmic nitrate reductase complex NapAB.
messages: Periplasm

935293:PL78 RS15500
gene id: 935293:PL78_RS15500
uniprot id: A0A3S6F3H0
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU.

935293:PL78 RS09985
gene id: 935293:PL78_RS09985
uniprot id: A0A3S6F0D3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

935293:PL78 RS06615
gene id: 935293:PL78_RS06615
uniprot id: A0A3S6EYX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Crl family.
messages: Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32.
messages: Cytoplasm

935293:PL78 RS03315
gene id: 935293:PL78_RS03315
uniprot id: A0A3S6EXP0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

935293:PL78 RS15530
gene id: 935293:PL78_RS15530
uniprot id: A0A3S6F3B0
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

935293:PL78 RS04650
gene id: 935293:PL78_RS04650
uniprot id: A0A3S6EYF6
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

935293:PL78 RS18275
gene id: 935293:PL78_RS18275
uniprot id: A0A3S6F4T6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS07895
gene id: 935293:PL78_RS07895
uniprot id: A0A3S6EZJ4
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

935293:PL78 RS09040
gene id: 935293:PL78_RS09040
uniprot id: A0A3S6F050
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

935293:PL78 RS03975
gene id: 935293:PL78_RS03975
uniprot id: A0A3S6EX13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

935293:PL78 RS10790
gene id: 935293:PL78_RS10790
uniprot id: A0A3S6F0T5
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

935293:PL78 RS07075
gene id: 935293:PL78_RS07075
uniprot id: A0A3S6EZR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 3'-5' exonuclease that prefers single-stranded DNA and RNA. May play a role in the H(2)O(2)-induced DNA damage repair.
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily.
messages: Cytoplasm
messages: Monomer.

935293:PL78 RS08505
gene id: 935293:PL78_RS08505
uniprot id: A0A3S6F0I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

935293:PL78 RS01145
gene id: 935293:PL78_RS01145
uniprot id: A0A3S6EVV8
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

935293:PL78 RS05120
gene id: 935293:PL78_RS05120
uniprot id: A0A3S6EXU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

935293:PL78 RS16855
gene id: 935293:PL78_RS16855
uniprot id: A0A3S6F4E6
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

935293:PL78 RS17760
gene id: 935293:PL78_RS17760
uniprot id: A0A3S6F685
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

935293:PL78 RS06910
gene id: 935293:PL78_RS06910
uniprot id: E7BXF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

935293:PL78 RS07600
gene id: 935293:PL78_RS07600
uniprot id: A0A3S6EZ17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

935293:PL78 RS17155
gene id: 935293:PL78_RS17155
uniprot id: A0A3S6F5B6
names: Similarity
messages: Belongs to the elongation factor P family.

935293:PL78 RS01270
gene id: 935293:PL78_RS01270
uniprot id: A0A3S6EVN2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

935293:PL78 RS14390
gene id: 935293:PL78_RS14390
uniprot id: A0A3S6F2R8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

935293:PL78 RS09015
gene id: 935293:PL78_RS09015
uniprot id: A0A3S6EZR9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

935293:PL78 RS14365
gene id: 935293:PL78_RS14365
uniprot id: A0A3S6F307
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

935293:PL78 RS03040
gene id: 935293:PL78_RS03040
uniprot id: A0A3S6EY32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

935293:PL78 RS08910
gene id: 935293:PL78_RS08910
uniprot id: A0A3S6EZQ1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS04145
gene id: 935293:PL78_RS04145
uniprot id: A0A3S6EY60
names: Function
names: Similarity
messages: Belongs to the arginine N-succinyltransferase family.
messages: Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine.

935293:PL78 RS04565
gene id: 935293:PL78_RS04565
uniprot id: A0A3S6EXS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

935293:PL78 RS14505
gene id: 935293:PL78_RS14505
uniprot id: A0A3S6F310
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

935293:PL78 RS11160
gene id: 935293:PL78_RS11160
uniprot id: A0A3S6F0Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

935293:PL78 RS06705
gene id: 935293:PL78_RS06705
uniprot id: A0A3S6EYK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
messages: Homodimer.

935293:PL78 RS07910
gene id: 935293:PL78_RS07910
uniprot id: A0A3S6F0N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

935293:PL78 RS12655
gene id: 935293:PL78_RS12655
uniprot id: A0A3S6F3C7
names: Similarity
names: Subunit
messages: Belongs to the ViaA family.
messages: Possible formation of a ternary complex RavA-ViaA-CadA.

935293:PL78 RS16560
gene id: 935293:PL78_RS16560
uniprot id: A0A3S6F3X9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS05555
gene id: 935293:PL78_RS05555
uniprot id: A0A3S6EXV9
names: Similarity
messages: Belongs to the peptidase S1B family.

935293:PL78 RS02360
gene id: 935293:PL78_RS02360
uniprot id: A0A3S6EW37
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

935293:PL78 RS03295
gene id: 935293:PL78_RS03295
uniprot id: A0A3S6EY84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

935293:PL78 RS09915
gene id: 935293:PL78_RS09915
uniprot id: A0A3S6F1V0
names: Similarity
messages: Belongs to the UPF0441 family.

935293:PL78 RS14240
gene id: 935293:PL78_RS14240
uniprot id: A0A3S6F2P2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

935293:PL78 RS11710
gene id: 935293:PL78_RS11710
uniprot id: A0A3S6F195
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

935293:PL78 RS02320
gene id: 935293:PL78_RS02320
uniprot id: A0A3S6EWI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

935293:PL78 RS13050
gene id: 935293:PL78_RS13050
uniprot id: A0A3S6F1Z7
names: Subcellular Location Annotation
messages: Cell inner membrane

935293:PL78 RS14160
gene id: 935293:PL78_RS14160
uniprot id: A0A3S6F2T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

935293:PL78 RS08260
gene id: 935293:PL78_RS08260
uniprot id: A0A3S6F0W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
messages: Homodimer.
messages: With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P.

935293:PL78 RS02930
gene id: 935293:PL78_RS02930
uniprot id: A0A3S6EWT6
names: Similarity
messages: Belongs to the acylphosphatase family.

935293:PL78 RS06750
gene id: 935293:PL78_RS06750
uniprot id: A0A3S6EYK5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

935293:PL78 RS01105
gene id: 935293:PL78_RS01105
uniprot id: A0A3S6EVT2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

935293:PL78 RS10535
gene id: 935293:PL78_RS10535
uniprot id: A0A3S6F1M8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

935293:PL78 RS13135
gene id: 935293:PL78_RS13135
uniprot id: A0A3S6F2D4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

935293:PL78 RS12075
gene id: 935293:PL78_RS12075
uniprot id: A0A3S6F1J6
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS01765
gene id: 935293:PL78_RS01765
uniprot id: A0A3S6EW73
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

935293:PL78 RS10460
gene id: 935293:PL78_RS10460
uniprot id: A0A3S6F0Y1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

935293:PL78 RS11695
gene id: 935293:PL78_RS11695
uniprot id: A0A3S6F1M9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Monomer.

935293:PL78 RS02350
gene id: 935293:PL78_RS02350
uniprot id: A0A3S6EW39
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

935293:PL78 RS17660
gene id: 935293:PL78_RS17660
uniprot id: A0A3S6F663
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

935293:PL78 RS00880
gene id: 935293:PL78_RS00880
uniprot id: A0A3S6EV89
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS17710
gene id: 935293:PL78_RS17710
uniprot id: A0A3S6F673
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

935293:PL78 RS05090
gene id: 935293:PL78_RS05090
uniprot id: A0A3S6EZ86
names: Subcellular Location Annotation
messages: Cytoplasm

935293:PL78 RS18210
gene id: 935293:PL78_RS18210
uniprot id: A0A3S6F4U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SipA/IpaA family.
messages: Secreted

935293:PL78 RS16055
gene id: 935293:PL78_RS16055
uniprot id: A0A3S6F3S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

935293:PL78 RS00450
gene id: 935293:PL78_RS00450
uniprot id: A0A3S6EUX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

935293:PL78 RS10750
gene id: 935293:PL78_RS10750
uniprot id: A0A3S6F137
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

935293:PL78 RS04465
gene id: 935293:PL78_RS04465
uniprot id: A0A3S6EXQ4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

935293:PL78 RS14480
gene id: 935293:PL78_RS14480
uniprot id: A0A3S6F2R6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

935293:PL78 RS15315
gene id: 935293:PL78_RS15315
uniprot id: A0A3S6F378
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

935293:PL78 RS04415
gene id: 935293:PL78_RS04415
uniprot id: A0A3S6EXE8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS01695
gene id: 935293:PL78_RS01695
uniprot id: A0A3S6EVQ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

935293:PL78 RS02980
gene id: 935293:PL78_RS02980
uniprot id: A0A3S6EWE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. OpgH subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
messages: Membrane

935293:PL78 RS16540
gene id: 935293:PL78_RS16540
uniprot id: A0A3S6F4X9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

935293:PL78 RS14920
gene id: 935293:PL78_RS14920
uniprot id: A0A3S6F4L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

935293:PL78 RS06760
gene id: 935293:PL78_RS06760
uniprot id: A0A3S6EYL8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

935293:PL78 RS08040
gene id: 935293:PL78_RS08040
uniprot id: A0A3S6EZG0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

935293:PL78 RS09605
gene id: 935293:PL78_RS09605
uniprot id: A0A3S6F016
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily.
messages: Cell inner membrane
messages: Homodimer. Interacts with KefC.
messages: Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefC. Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC.

935293:PL78 RS13090
gene id: 935293:PL78_RS13090
uniprot id: A0A3S6F3K8
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

935293:PL78 RS11425
gene id: 935293:PL78_RS11425
uniprot id: A0A3S6F166
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

935293:PL78 RS00305
gene id: 935293:PL78_RS00305
uniprot id: A0A3S6EUU1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

935293:PL78 RS05025
gene id: 935293:PL78_RS05025
uniprot id: A0A3S6EY13
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS16545
gene id: 935293:PL78_RS16545
uniprot id: A0A3S6F418
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

935293:PL78 RS19330
gene id: 935293:PL78_RS19330
uniprot id: B6A8C3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

935293:PL78 RS03105
gene id: 935293:PL78_RS03105
uniprot id: A0A3S6EWI4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

935293:PL78 RS02530
gene id: 935293:PL78_RS02530
uniprot id: A0A3S6EWJ9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

935293:PL78 RS17295
gene id: 935293:PL78_RS17295
uniprot id: A0A3S6F4D7
names: Similarity
messages: Belongs to the glycosyl hydrolase.

935293:PL78 RS18350
gene id: 935293:PL78_RS18350
uniprot id: A0A3S6F538
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

935293:PL78 RS07265
gene id: 935293:PL78_RS07265
uniprot id: A0A3S6EYT6
names: Similarity
messages: Belongs to the CdaR family.

935293:PL78 RS17670
gene id: 935293:PL78_RS17670
uniprot id: A0A3S6F4K5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

935293:PL78 RS08860
gene id: 935293:PL78_RS08860
uniprot id: A0A3S6EZP1
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

935293:PL78 RS01400
gene id: 935293:PL78_RS01400
uniprot id: A0A3S6EVH9
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

935293:PL78 RS15890
gene id: 935293:PL78_RS15890
uniprot id: A0A3S6F3M2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

935293:PL78 RS11550
gene id: 935293:PL78_RS11550
uniprot id: A0A3S6F2S2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

935293:PL78 RS10770
gene id: 935293:PL78_RS10770
uniprot id: A0A3S6F0N1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

935293:PL78 RS02720
gene id: 935293:PL78_RS02720
uniprot id: A0A3S6EWR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MukF family.
messages: Interacts, and probably forms a ternary complex, with MukE and MukB via its C-terminal region. The complex formation is stimulated by calcium or magnesium. It is required for an interaction between MukE and MukB.
messages: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
messages: nucleoid

935293:PL78 RS15800
gene id: 935293:PL78_RS15800
uniprot id: A0A3S6F4J0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

935293:PL78 RS16645
gene id: 935293:PL78_RS16645
uniprot id: A0A3S6F437
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0208 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

935293:PL78 RS11910
gene id: 935293:PL78_RS11910
uniprot id: A0A3S6F1F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

935293:PL78 RS18915
gene id: 935293:PL78_RS18915
uniprot id: A0A3S6F5B7
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS09745
gene id: 935293:PL78_RS09745
uniprot id: A0A3S6F0E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

935293:PL78 RS10785
gene id: 935293:PL78_RS10785
uniprot id: A0A3S6F1S8
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

935293:PL78 RS16775
gene id: 935293:PL78_RS16775
uniprot id: A0A3S6F402
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

935293:PL78 RS10255
gene id: 935293:PL78_RS10255
uniprot id: A0A3S6F0T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmG family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.

935293:PL78 RS05455
gene id: 935293:PL78_RS05455
uniprot id: A0A3S6EXU0
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS03265
gene id: 935293:PL78_RS03265
uniprot id: A0A3S6EWL4
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-90 and Arg-93) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase that specifically removes acetyl groups on target proteins. Also acts as a protein-lysine deacylase by mediating protein desuccinylation and de-2-hydroxyisobutyrylation. Modulates the activities of several proteins which are inactive in their acylated form.

935293:PL78 RS18335
gene id: 935293:PL78_RS18335
uniprot id: A0A3S6F502
names: Subunit
messages: Monomer.

935293:PL78 RS11485
gene id: 935293:PL78_RS11485
uniprot id: A0A3S6F1H6
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

935293:PL78 RS03965
gene id: 935293:PL78_RS03965
uniprot id: A0A3S6EYL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

935293:PL78 RS11905
gene id: 935293:PL78_RS11905
uniprot id: A0A3S6F1D4
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

935293:PL78 RS07865
gene id: 935293:PL78_RS07865
uniprot id: A0A3S6EZ30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraA family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.
messages: Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB.

935293:PL78 RS17290
gene id: 935293:PL78_RS17290
uniprot id: A0A3S6F4A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Oligosaccharide:H(+) symporter (OHS) (TC 2.A.1.5) family.
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS12905
gene id: 935293:PL78_RS12905
uniprot id: A0A3S6F202
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

935293:PL78 RS08815
gene id: 935293:PL78_RS08815
uniprot id: A0A3S6EZN7
names: Function
names: Similarity
messages: Belongs to the peptidase M16 family.
messages: Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin.

935293:PL78 RS11230
gene id: 935293:PL78_RS11230
uniprot id: A0A3S6F170
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

935293:PL78 RS06515
gene id: 935293:PL78_RS06515
uniprot id: A0A3S6EYV2
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

935293:PL78 RS07585
gene id: 935293:PL78_RS07585
uniprot id: A0A3S6EYZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

935293:PL78 RS00105
gene id: 935293:PL78_RS00105
uniprot id: A0A3S6EVX3
names: Similarity
messages: Belongs to the phage antitermination Q type 1 family.

935293:PL78 RS10955
gene id: 935293:PL78_RS10955
uniprot id: A0A3S6F0T2
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

935293:PL78 RS11115
gene id: 935293:PL78_RS11115
uniprot id: A0A3S6F2J5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

935293:PL78 RS02005
gene id: 935293:PL78_RS02005
uniprot id: A0A3S6EWX8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

935293:PL78 RS05875
gene id: 935293:PL78_RS05875
uniprot id: A0A3S6EY42
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS18230
gene id: 935293:PL78_RS18230
uniprot id: A0A3S6F4W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SctF family.
messages: Cell surface
messages: Secreted

935293:PL78 RS01150
gene id: 935293:PL78_RS01150
uniprot id: A0A3S6EVC9
names: Similarity
messages: Belongs to the DNA polymerase HolA subunit family.

935293:PL78 RS02160
gene id: 935293:PL78_RS02160
uniprot id: A0A3S6EVZ5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.
messages: Homotetramer.

935293:PL78 RS06025
gene id: 935293:PL78_RS06025
uniprot id: A0A3S6EY59
names: Similarity
messages: Belongs to the HesB/IscA family.

935293:PL78 RS13810
gene id: 935293:PL78_RS13810
uniprot id: A0A3S6F2M2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

935293:PL78 RS04130
gene id: 935293:PL78_RS04130
uniprot id: A0A3S6EX32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS06495
gene id: 935293:PL78_RS06495
uniprot id: A0A3S6EYF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell inner membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

935293:PL78 RS07280
gene id: 935293:PL78_RS07280
uniprot id: A0A3S6EYW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

935293:PL78 RS02495
gene id: 935293:PL78_RS02495
uniprot id: A0A3S6EW60
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

935293:PL78 RS16935
gene id: 935293:PL78_RS16935
uniprot id: A0A3S6F486
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS05735
gene id: 935293:PL78_RS05735
uniprot id: A0A3S6EYF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

935293:PL78 RS08760
gene id: 935293:PL78_RS08760
uniprot id: A0A3S6EZN9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

935293:PL78 RS08905
gene id: 935293:PL78_RS08905
uniprot id: A0A3S6EZM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

935293:PL78 RS02285
gene id: 935293:PL78_RS02285
uniprot id: A0A3S6EXN5
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

935293:PL78 RS12740
gene id: 935293:PL78_RS12740
uniprot id: A0A3S6F1X3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

935293:PL78 RS18860
gene id: 935293:PL78_RS18860
uniprot id: A0A3S6F5A5
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

935293:PL78 RS03145
gene id: 935293:PL78_RS03145
uniprot id: A0A3S6EWJ2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

935293:PL78 RS12435
gene id: 935293:PL78_RS12435
uniprot id: A0A3S6F1V6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

935293:PL78 RS08035
gene id: 935293:PL78_RS08035
uniprot id: A0A3S6EZ99
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

935293:PL78 RS07640
gene id: 935293:PL78_RS07640
uniprot id: A0A3S6EZ16
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

935293:PL78 RS15695
gene id: 935293:PL78_RS15695
uniprot id: A0A3S6F3I7
names: Similarity
messages: Belongs to the heat shock protein 70 family.

935293:PL78 RS17255
gene id: 935293:PL78_RS17255
uniprot id: A0A3S6F4F1
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

935293:PL78 RS06610
gene id: 935293:PL78_RS06610
uniprot id: A0A3S6EYN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

935293:PL78 RS10720
gene id: 935293:PL78_RS10720
uniprot id: A0A3S6F0M0
names: Similarity
messages: Belongs to the peptidase U62 family.

935293:PL78 RS08740
gene id: 935293:PL78_RS08740
uniprot id: A0A3S6EZI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

935293:PL78 RS03005
gene id: 935293:PL78_RS03005
uniprot id: A0A3S6EWH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily.
messages: Cell membrane
messages: Membrane

935293:PL78 RS14540
gene id: 935293:PL78_RS14540
uniprot id: A0A3S6F2W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YscJ lipoprotein family.
messages: Cell outer membrane
messages: Membrane

935293:PL78 RS17580
gene id: 935293:PL78_RS17580
uniprot id: A0A3S6F5J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS03230
gene id: 935293:PL78_RS03230
uniprot id: A0A3S6EWK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS09770
gene id: 935293:PL78_RS09770
uniprot id: A0A3S6F035
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Fes family.
messages: Cytoplasm

935293:PL78 RS03905
gene id: 935293:PL78_RS03905
uniprot id: A0A3S6EWY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

935293:PL78 RS03015
gene id: 935293:PL78_RS03015
uniprot id: A0A3S6EWG4
names: Similarity
messages: Belongs to the YciI family.

935293:PL78 RS14930
gene id: 935293:PL78_RS14930
uniprot id: A0A3S6F320
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS09070
gene id: 935293:PL78_RS09070
uniprot id: A0A3S6EZT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-modifying YgfZ family.
messages: Cytoplasm
messages: Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.

935293:PL78 RS13705
gene id: 935293:PL78_RS13705
uniprot id: A0A3S6F2F9
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

935293:PL78 RS12545
gene id: 935293:PL78_RS12545
uniprot id: A0A3S6F1P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS03150
gene id: 935293:PL78_RS03150
uniprot id: A0A3S6EWK3
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

935293:PL78 RS08030
gene id: 935293:PL78_RS08030
uniprot id: A0A3S6F091
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

935293:PL78 RS17175
gene id: 935293:PL78_RS17175
uniprot id: A0A3S6F4A3
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TorC/TorY family.
messages: Binds 5 heme groups per subunit.
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS07100
gene id: 935293:PL78_RS07100
uniprot id: A0A3S6EZ10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

935293:PL78 RS16740
gene id: 935293:PL78_RS16740
uniprot id: A0A3S6F524
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4 family.
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: Membrane

935293:PL78 RS00415
gene id: 935293:PL78_RS00415
uniprot id: A0A3S6EW35
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane
messages: The cytochrome bo(3) ubiquinol oxidase complex is a heterooctamer of two A chains, two B chains, two C chains and two D chains.

935293:PL78 RS06920
gene id: 935293:PL78_RS06920
uniprot id: A0A3S6EYM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

935293:PL78 RS14960
gene id: 935293:PL78_RS14960
uniprot id: A0A3S6F305
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

935293:PL78 RS05625
gene id: 935293:PL78_RS05625
uniprot id: A0A3S6EXX0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.
messages: Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin.

935293:PL78 RS09375
gene id: 935293:PL78_RS09375
uniprot id: A0A3S6F000
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

935293:PL78 RS09470
gene id: 935293:PL78_RS09470
uniprot id: A0A3S6F010
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

935293:PL78 RS01160
gene id: 935293:PL78_RS01160
uniprot id: A0A3S6EX27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

935293:PL78 RS14950
gene id: 935293:PL78_RS14950
uniprot id: A0A3S6F390
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

935293:PL78 RS11025
gene id: 935293:PL78_RS11025
uniprot id: A0A3S6F0W9
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the porin LamB (TC 1.B.3) family.
messages: By maltose.
messages: Cell outer membrane
messages: Homotrimer formed of three 18-stranded antiparallel beta-barrels, containing three independent channels.
messages: Involved in the transport of maltose and maltodextrins.
messages: Membrane

935293:PL78 RS07330
gene id: 935293:PL78_RS07330
uniprot id: A0A3S6EYW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Interacts with IscS.
messages: Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.

935293:PL78 RS16160
gene id: 935293:PL78_RS16160
uniprot id: A0A3S6F428
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS12605
gene id: 935293:PL78_RS12605
uniprot id: A0A3S6F3B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

935293:PL78 RS11190
gene id: 935293:PL78_RS11190
uniprot id: A0A3S6F0X0
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

935293:PL78 RS08045
gene id: 935293:PL78_RS08045
uniprot id: A0A3S6EZM2
names: Similarity
messages: Belongs to the UPF0758 family. YicR subfamily.

935293:PL78 RS02830
gene id: 935293:PL78_RS02830
uniprot id: A0A3S6EWR7
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

935293:PL78 RS15190
gene id: 935293:PL78_RS15190
uniprot id: A0A3S6F386
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

935293:PL78 RS09100
gene id: 935293:PL78_RS09100
uniprot id: A0A3S6F057
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

935293:PL78 RS07030
gene id: 935293:PL78_RS07030
uniprot id: A0A3S6EYQ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

935293:PL78 RS11760
gene id: 935293:PL78_RS11760
uniprot id: A0A3S6F1A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

935293:PL78 RS05145
gene id: 935293:PL78_RS05145
uniprot id: A0A3S6EXM8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

935293:PL78 RS02315
gene id: 935293:PL78_RS02315
uniprot id: A0A3S6EW90
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

935293:PL78 RS11295
gene id: 935293:PL78_RS11295
uniprot id: A0A3S6F1F0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

935293:PL78 RS14660
gene id: 935293:PL78_RS14660
uniprot id: A0A3S6F361
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS09585
gene id: 935293:PL78_RS09585
uniprot id: A0A3S6F139
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

935293:PL78 RS17860
gene id: 935293:PL78_RS17860
uniprot id: A0A3S6F6A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

935293:PL78 RS00765
gene id: 935293:PL78_RS00765
uniprot id: A0A3S6EV48
names: Similarity
messages: Belongs to the phosphohexose mutase family.

935293:PL78 RS14330
gene id: 935293:PL78_RS14330
uniprot id: A0A3S6F496
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

935293:PL78 RS18535
gene id: 935293:PL78_RS18535
uniprot id: A0A3S6F5D1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

935293:PL78 RS06700
gene id: 935293:PL78_RS06700
uniprot id: A0A3S6EZK1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

935293:PL78 RS07590
gene id: 935293:PL78_RS07590
uniprot id: A0A3S6EZ03
names: Function
names: Similarity
messages: Belongs to the GppA/Ppx family. GppA subfamily.
messages: Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.

935293:PL78 RS17675
gene id: 935293:PL78_RS17675
uniprot id: A0A3S6F4M4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

935293:PL78 RS01280
gene id: 935293:PL78_RS01280
uniprot id: A0A3S6EVF0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS10840
gene id: 935293:PL78_RS10840
uniprot id: A0A3S6F0U5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS13345
gene id: 935293:PL78_RS13345
uniprot id: A0A3S6F241
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

935293:PL78 RS12985
gene id: 935293:PL78_RS12985
uniprot id: A0A3S6F2C8
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

935293:PL78 RS12330
gene id: 935293:PL78_RS12330
uniprot id: A0A3S6F1P1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

935293:PL78 RS10590
gene id: 935293:PL78_RS10590
uniprot id: A0A3S6F0Q0
names: Similarity
messages: Belongs to the RutC family.

935293:PL78 RS11315
gene id: 935293:PL78_RS11315
uniprot id: A0A3S6F142
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

935293:PL78 RS09465
gene id: 935293:PL78_RS09465
uniprot id: A0A3S6EZY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

935293:PL78 RS15600
gene id: 935293:PL78_RS15600
uniprot id: A0A3S6F3J0
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

935293:PL78 RS06735
gene id: 935293:PL78_RS06735
uniprot id: A0A3S6EYI2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

935293:PL78 RS13770
gene id: 935293:PL78_RS13770
uniprot id: A0A3S6F2C4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

935293:PL78 RS17850
gene id: 935293:PL78_RS17850
uniprot id: A0A3S6F4M9
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

935293:PL78 RS15845
gene id: 935293:PL78_RS15845
uniprot id: A0A3S6F3L3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

935293:PL78 RS13765
gene id: 935293:PL78_RS13765
uniprot id: A0A3S6F2P5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS03160
gene id: 935293:PL78_RS03160
uniprot id: A0A3S6EXK9
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

935293:PL78 RS00410
gene id: 935293:PL78_RS00410
uniprot id: A0A3S6EUX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

935293:PL78 RS14640
gene id: 935293:PL78_RS14640
uniprot id: A0A3S6F2Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the invasin protein D family.
messages: Secreted

935293:PL78 RS02340
gene id: 935293:PL78_RS02340
uniprot id: A0A3S6EW23
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

935293:PL78 RS07450
gene id: 935293:PL78_RS07450
uniprot id: A0A3S6EZ83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

935293:PL78 RS14765
gene id: 935293:PL78_RS14765
uniprot id: A0A3S6F3Z5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

935293:PL78 RS11555
gene id: 935293:PL78_RS11555
uniprot id: A0A3S6F140
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

935293:PL78 RS05255
gene id: 935293:PL78_RS05255
uniprot id: A0A3S6EXR3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

935293:PL78 RS15055
gene id: 935293:PL78_RS15055
uniprot id: A0A3S6F3D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

935293:PL78 RS14940
gene id: 935293:PL78_RS14940
uniprot id: A0A3S6F421
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

935293:PL78 RS07915
gene id: 935293:PL78_RS07915
uniprot id: A0A3S6EZ40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

935293:PL78 RS17115
gene id: 935293:PL78_RS17115
uniprot id: A0A3S6F4F0
names: Similarity
messages: Belongs to the peptidase C40 family.

935293:PL78 RS14085
gene id: 935293:PL78_RS14085
uniprot id: A0A3S6F2I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

935293:PL78 RS01815
gene id: 935293:PL78_RS01815
uniprot id: A0A3S6EW83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

935293:PL78 RS03270
gene id: 935293:PL78_RS03270
uniprot id: A0A3S6EWS8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

935293:PL78 RS17050
gene id: 935293:PL78_RS17050
uniprot id: A0A3S6F4A6
names: Similarity
messages: Belongs to the UPF0352 family.

935293:PL78 RS12335
gene id: 935293:PL78_RS12335
uniprot id: A0A3S6F1T5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

935293:PL78 RS18205
gene id: 935293:PL78_RS18205
uniprot id: A0A3S6F562
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the invasin protein D family.
messages: Secreted

935293:PL78 RS01395
gene id: 935293:PL78_RS01395
uniprot id: A0A3S6EVI4
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-II family.

935293:PL78 RS07920
gene id: 935293:PL78_RS07920
uniprot id: A0A3S6EZ56
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.

935293:PL78 RS08535
gene id: 935293:PL78_RS08535
uniprot id: A0A3S6F112
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

935293:PL78 RS04085
gene id: 935293:PL78_RS04085
uniprot id: A0A3S6EX15
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

935293:PL78 RS05640
gene id: 935293:PL78_RS05640
uniprot id: A0A3S6EXW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Cell inner membrane
messages: Membrane
messages: Zinc transporter. Acts as a Zn(2+):proton symporter, which likely mediates zinc ion uptake.

935293:PL78 RS07460
gene id: 935293:PL78_RS07460
uniprot id: A0A3S6EYV8
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

935293:PL78 RS18660
gene id: 935293:PL78_RS18660
uniprot id: A0A3S6F563
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

935293:PL78 RS12945
gene id: 935293:PL78_RS12945
uniprot id: A0A3S6F1W4
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS05070
gene id: 935293:PL78_RS05070
uniprot id: A0A3S6EXT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

935293:PL78 RS03225
gene id: 935293:PL78_RS03225
uniprot id: A0A3S6EX14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

935293:PL78 RS07815
gene id: 935293:PL78_RS07815
uniprot id: A0A3S6EZ20
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

935293:PL78 RS09450
gene id: 935293:PL78_RS09450
uniprot id: A0A3S6EZY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

935293:PL78 RS07875
gene id: 935293:PL78_RS07875
uniprot id: A0A3S6EZ51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

935293:PL78 RS12010
gene id: 935293:PL78_RS12010
uniprot id: A0A3S6F1I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose.
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS07350
gene id: 935293:PL78_RS07350
uniprot id: A0A3S6EZ61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anaerobic G-3-P dehydrogenase subunit B family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor.

935293:PL78 RS02125
gene id: 935293:PL78_RS02125
uniprot id: A0A3S6EVW8
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

935293:PL78 RS16800
gene id: 935293:PL78_RS16800
uniprot id: A0A3S6F488
names: Similarity
messages: Belongs to the UPF0303 family.

935293:PL78 RS15460
gene id: 935293:PL78_RS15460
uniprot id: A0A3S6F3L9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family. RcnA subfamily.
messages: Cell membrane
messages: Efflux system for nickel and cobalt.
messages: Membrane

935293:PL78 RS12590
gene id: 935293:PL78_RS12590
uniprot id: A0A3S6F236
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

935293:PL78 RS15750
gene id: 935293:PL78_RS15750
uniprot id: A0A3S6F4H9
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

935293:PL78 RS15440
gene id: 935293:PL78_RS15440
uniprot id: A0A3S6F3D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

935293:PL78 RS15320
gene id: 935293:PL78_RS15320
uniprot id: A0A3S6F3M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

935293:PL78 RS02365
gene id: 935293:PL78_RS02365
uniprot id: A0A3S6EWA0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS18810
gene id: 935293:PL78_RS18810
uniprot id: A0A3S6F593
names: Similarity
messages: Belongs to the peptidase S24 family.

935293:PL78 RS14605
gene id: 935293:PL78_RS14605
uniprot id: A0A3S6F330
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS09130
gene id: 935293:PL78_RS09130
uniprot id: A0A3S6EZW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

935293:PL78 RS07470
gene id: 935293:PL78_RS07470
uniprot id: A0A3S6EYY4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

935293:PL78 RS01920
gene id: 935293:PL78_RS01920
uniprot id: A0A3S6EVS4
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

935293:PL78 RS16060
gene id: 935293:PL78_RS16060
uniprot id: A0A3S6F3V1
names: Subcellular Location Annotation
messages: Cytoplasm

935293:PL78 RS10530
gene id: 935293:PL78_RS10530
uniprot id: A0A3S6F0N5
names: Similarity
names: Subunit
messages: Belongs to the SIS family. GutQ/KpsF subfamily.
messages: Homotetramer.

935293:PL78 RS07240
gene id: 935293:PL78_RS07240
uniprot id: A0A3S6EZ78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

935293:PL78 RS04165
gene id: 935293:PL78_RS04165
uniprot id: A0A3S6EX31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Membrane

935293:PL78 RS03640
gene id: 935293:PL78_RS03640
uniprot id: A0A3S6EX63
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS09545
gene id: 935293:PL78_RS09545
uniprot id: A0A3S6F0F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.

935293:PL78 RS15340
gene id: 935293:PL78_RS15340
uniprot id: A0A3S6F3B9
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS06915
gene id: 935293:PL78_RS06915
uniprot id: A0A3S6EYL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

935293:PL78 RS17885
gene id: 935293:PL78_RS17885
uniprot id: A0A3S6F4R5
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS02885
gene id: 935293:PL78_RS02885
uniprot id: A0A3S6EY06
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

935293:PL78 RS05615
gene id: 935293:PL78_RS05615
uniprot id: A0A3S6EXX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS14905
gene id: 935293:PL78_RS14905
uniprot id: A0A3S6F3A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: Membrane

935293:PL78 RS14125
gene id: 935293:PL78_RS14125
uniprot id: A0A3S6F2Z0
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS02675
gene id: 935293:PL78_RS02675
uniprot id: A0A3S6EW82
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

935293:PL78 RS04155
gene id: 935293:PL78_RS04155
uniprot id: A0A3S6EXA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

935293:PL78 RS02640
gene id: 935293:PL78_RS02640
uniprot id: A0A3S6EW85
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS17030
gene id: 935293:PL78_RS17030
uniprot id: A0A3S6F5T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

935293:PL78 RS06635
gene id: 935293:PL78_RS06635
uniprot id: A0A3S6EYG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

935293:PL78 RS07810
gene id: 935293:PL78_RS07810
uniprot id: A0A3S6F0L6
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

935293:PL78 RS06725
gene id: 935293:PL78_RS06725
uniprot id: A0A3S6EYU8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

935293:PL78 RS17755
gene id: 935293:PL78_RS17755
uniprot id: A0A3S6F507
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

935293:PL78 RS15025
gene id: 935293:PL78_RS15025
uniprot id: A0A3S6F316
names: Subcellular Location Annotation
messages: Cytoplasm

935293:PL78 RS13710
gene id: 935293:PL78_RS13710
uniprot id: A0A3S6F2K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

935293:PL78 RS09030
gene id: 935293:PL78_RS09030
uniprot id: A0A3S6EZU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

935293:PL78 RS07165
gene id: 935293:PL78_RS07165
uniprot id: A0A3S6EYR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS13775
gene id: 935293:PL78_RS13775
uniprot id: A0A3S6F2S0
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

935293:PL78 RS02500
gene id: 935293:PL78_RS02500
uniprot id: A0A3S6EW68
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A peripheral cell membrane enzyme that catalyzes the oxidative decarboxylation of pyruvate to form acetate and CO(2). It channels electrons from the cytoplasm to the respiratory chain at the cell membrane via ubiquinone.
messages: Belongs to the TPP enzyme family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Cell membrane
messages: Has 4 domains; the Pyr domain which binds the pyrimidine moiety of the thiamine pyrophosphate cofactor, the FAD-binding domain, the PP-binding domain which binds the pyrophosphate portion of thiamine pyrophosphate and the C-terminal membrane binding region. The C-terminus is held closely against the rest of the protein and covers the active site; during activation it unfolds from the rest of the protein and forms an amphipathic helix upon membrane binding, exposing the active site.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The C-terminus inhibits activity; it has to move for the enzyme to be active. Activated by lipid-binding, which occurs via the C-terminus.

935293:PL78 RS14135
gene id: 935293:PL78_RS14135
uniprot id: A0A3S6F2I8
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

935293:PL78 RS07025
gene id: 935293:PL78_RS07025
uniprot id: A0A3S6EZQ4
names: Similarity
messages: Belongs to the IMPACT family.

935293:PL78 RS13735
gene id: 935293:PL78_RS13735
uniprot id: A0A3S6F2B2
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS10365
gene id: 935293:PL78_RS10365
uniprot id: A0A3S6F0F7
names: Similarity
messages: Belongs to the pirin family.

935293:PL78 RS15225
gene id: 935293:PL78_RS15225
uniprot id: A0A3S6F4R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

935293:PL78 RS10690
gene id: 935293:PL78_RS10690
uniprot id: A0A3S6F0R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease N1/T1 family.
messages: Secreted

935293:PL78 RS04305
gene id: 935293:PL78_RS04305
uniprot id: A0A3S6EXD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

935293:PL78 RS09880
gene id: 935293:PL78_RS09880
uniprot id: A0A3S6F0A1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS11375
gene id: 935293:PL78_RS11375
uniprot id: E7BXF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

935293:PL78 RS08280
gene id: 935293:PL78_RS08280
uniprot id: A0A3S6F0E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FrdD family.
messages: Cell membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.

935293:PL78 RS03925
gene id: 935293:PL78_RS03925
uniprot id: A0A3S6EX01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

935293:PL78 RS15270
gene id: 935293:PL78_RS15270
uniprot id: A0A3S6F3L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

935293:PL78 RS08110
gene id: 935293:PL78_RS08110
uniprot id: A0A3S6F0S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

935293:PL78 RS00755
gene id: 935293:PL78_RS00755
uniprot id: A0A3S6EWU4
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

935293:PL78 RS13080
gene id: 935293:PL78_RS13080
uniprot id: A0A3S6F1Z3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS06985
gene id: 935293:PL78_RS06985
uniprot id: A0A3S6F067
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

935293:PL78 RS13115
gene id: 935293:PL78_RS13115
uniprot id: A0A3S6F245
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

935293:PL78 RS07945
gene id: 935293:PL78_RS07945
uniprot id: A0A3S6EZK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

935293:PL78 RS02650
gene id: 935293:PL78_RS02650
uniprot id: A0A3S6EW99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

935293:PL78 RS10335
gene id: 935293:PL78_RS10335
uniprot id: A0A3S6F0K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS03775
gene id: 935293:PL78_RS03775
uniprot id: B6A879
names: Activity Regulation
names: Disruption Phenotype
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 18 family.
messages: Cells with a disrupted yenA1-yenA2-chi2-yenB-yenC1-yenC2 locus are no longer pathogenic in C.zealandica larvae.
messages: Part of an orally active toxin complex (TC) with strong insecticidal effects on larvae of the Coleoptera Costelytra zealandica, Acrossidius tasmania and Adoryphorus couloni and some Lepidoptera larvae (PubMed:21278295). The TC has an endochitinase activity (PubMed:21278295, PubMed:22158901) (Probable). This subunit might aid infection by degradation of the larval peritrophic membrane (Probable).
messages: Secreted
messages: Semipurified toxin complex consists of at least YenA1-YenA2-YenB-YenC1-YenC2-Chi1-Chi2 (PubMed:21278295). The Yen-TC:K9 subcomplex is about 26 nm tall and 22 nm in diameter with 5-fold symmetry and 5 copies of YenA1, YenA2, Chi1 and Chi2; the chitinase subunits may be solvent accessible on the exterior the complex (PubMed:22158901). The Yen-TC:K9 subcomplex has no insecticidal activity (PubMed:22158901). The native complex with additional YenB, YenC1 and YenC2 subunits is 16 nm taller and is insecticidal; the toxicity-conferring subunits are present at about 1 copy each (PubMed:22158901).
messages: Toxin complex is secreted when grown at 25 degrees Celsius or less; at higher temperatures the proteins are present intracellularly but not secreted.

935293:PL78 RS14475
gene id: 935293:PL78_RS14475
uniprot id: A0A3S6F4C5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

935293:PL78 RS17530
gene id: 935293:PL78_RS17530
uniprot id: A0A3S6F5I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS15945
gene id: 935293:PL78_RS15945
uniprot id: A0A3S6F3N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

935293:PL78 RS00490
gene id: 935293:PL78_RS00490
uniprot id: A0A3S6EVF5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

935293:PL78 RS05000
gene id: 935293:PL78_RS05000
uniprot id: A0A3S6EXL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

935293:PL78 RS05260
gene id: 935293:PL78_RS05260
uniprot id: A0A3S6EXQ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS14380
gene id: 935293:PL78_RS14380
uniprot id: A0A3S6F4A4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

935293:PL78 RS04570
gene id: 935293:PL78_RS04570
uniprot id: A0A3S6EXB7
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

935293:PL78 RS01610
gene id: 935293:PL78_RS01610
uniprot id: A0A3S6EVU5
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

935293:PL78 RS11070
gene id: 935293:PL78_RS11070
uniprot id: A0A3S6F0U1
names: Similarity
messages: Belongs to the aspartokinase family.

935293:PL78 RS15335
gene id: 935293:PL78_RS15335
uniprot id: A0A3S6F3B6
names: Function
names: Induction
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Induced by MurNAc 6-phosphate that releases the repressor MurR from the DNA. Repressed by MurR in the absence of MurNAc 6-phosphate.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

935293:PL78 RS12445
gene id: 935293:PL78_RS12445
uniprot id: A0A3S6F1M1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

935293:PL78 RS01290
gene id: 935293:PL78_RS01290
uniprot id: A0A3S6EX47
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

935293:PL78 RS16900
gene id: 935293:PL78_RS16900
uniprot id: A0A3S6F4B0
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

935293:PL78 RS17810
gene id: 935293:PL78_RS17810
uniprot id: A0A3S6F699
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

935293:PL78 RS04545
gene id: 935293:PL78_RS04545
uniprot id: A0A3S6EXA5
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

935293:PL78 RS18645
gene id: 935293:PL78_RS18645
uniprot id: A0A3S6F5H4
names: Function
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.
messages: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.

935293:PL78 RS07660
gene id: 935293:PL78_RS07660
uniprot id: A0A3S6EZF7
names: Function
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.
messages: Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.

935293:PL78 RS01490
gene id: 935293:PL78_RS01490
uniprot id: A0A3S6EX87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS07835
gene id: 935293:PL78_RS07835
uniprot id: A0A3S6EZ57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

935293:PL78 RS13150
gene id: 935293:PL78_RS13150
uniprot id: A0A3S6F3M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

935293:PL78 RS08660
gene id: 935293:PL78_RS08660
uniprot id: A0A3S6EZL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

935293:PL78 RS03850
gene id: 935293:PL78_RS03850
uniprot id: A0A3S6EWX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

935293:PL78 RS17405
gene id: 935293:PL78_RS17405
uniprot id: A0A3S6F4F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

935293:PL78 RS02455
gene id: 935293:PL78_RS02455
uniprot id: A0A3S6EX69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

935293:PL78 RS12400
gene id: 935293:PL78_RS12400
uniprot id: A0A3S6F215
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: Monomer. Forms homomultimers of about 100-150 subunits at optimal growth temperatures. Conformation changes to monomers at high temperatures or high ionic concentrations.

935293:PL78 RS04280
gene id: 935293:PL78_RS04280
uniprot id: A0A3S6EX61
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

935293:PL78 RS13180
gene id: 935293:PL78_RS13180
uniprot id: A0A3S6F265
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

935293:PL78 RS07520
gene id: 935293:PL78_RS07520
uniprot id: A0A3S6EZ93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WzyE family.
messages: Cell inner membrane
messages: Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units.
messages: Probably part of a complex composed of WzxE, WzyE and WzzE.

935293:PL78 RS07355
gene id: 935293:PL78_RS07355
uniprot id: A0A3S6F0D2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Membrane

935293:PL78 RS07580
gene id: 935293:PL78_RS07580
uniprot id: A0A3S6EYX6
names: Similarity
messages: Belongs to the thioredoxin family.

935293:PL78 RS08150
gene id: 935293:PL78_RS08150
uniprot id: A0A3S6EZ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

935293:PL78 RS09810
gene id: 935293:PL78_RS09810
uniprot id: A0A3S6F0J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

935293:PL78 RS11575
gene id: 935293:PL78_RS11575
uniprot id: A0A3S6F196
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TsgA family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

935293:PL78 RS17725
gene id: 935293:PL78_RS17725
uniprot id: A0A3S6F4N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

935293:PL78 RS07965
gene id: 935293:PL78_RS07965
uniprot id: A0A3S6EZ48
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

935293:PL78 RS19035
gene id: 935293:PL78_RS19035
uniprot id: A0A3S6F5R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS10570
gene id: 935293:PL78_RS10570
uniprot id: A0A3S6F0J5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RapZ-like family. RapZ subfamily.
messages: Homotrimer.
messages: Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.

935293:PL78 RS11665
gene id: 935293:PL78_RS11665
uniprot id: A0A3S6F1B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

935293:PL78 RS04525
gene id: 935293:PL78_RS04525
uniprot id: A0A3S6EXN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtJ subfamily.
messages: Catalyzes the excretion of spermidine.
messages: Cell membrane
messages: Forms a complex with MdtI.
messages: Membrane

935293:PL78 RS11060
gene id: 935293:PL78_RS11060
uniprot id: A0A3S6F1A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

935293:PL78 RS06870
gene id: 935293:PL78_RS06870
uniprot id: A0A3S6EYL7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

935293:PL78 RS13945
gene id: 935293:PL78_RS13945
uniprot id: A0A3S6F2J9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS10045
gene id: 935293:PL78_RS10045
uniprot id: A0A3S6F0Q1
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

935293:PL78 RS06130
gene id: 935293:PL78_RS06130
uniprot id: A0A3S6EY80
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Homohexamer, formed by a dimer of trimers.
messages: In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: In the N-terminal section; belongs to the Fmt family. UDP-L-Ara4N formyltransferase subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS08765
gene id: 935293:PL78_RS08765
uniprot id: A0A3S6EZV7
names: Similarity
messages: Belongs to the SufE family.

935293:PL78 RS04925
gene id: 935293:PL78_RS04925
uniprot id: A0A3S6EXZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

935293:PL78 RS11015
gene id: 935293:PL78_RS11015
uniprot id: A0A3S6F2H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Monomer.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

935293:PL78 RS01630
gene id: 935293:PL78_RS01630
uniprot id: A0A3S6EXA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS12230
gene id: 935293:PL78_RS12230
uniprot id: A0A3S6F1M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

935293:PL78 RS08065
gene id: 935293:PL78_RS08065
uniprot id: A0A3S6EZ69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

935293:PL78 RS17685
gene id: 935293:PL78_RS17685
uniprot id: A0A3S6F4M6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

935293:PL78 RS13875
gene id: 935293:PL78_RS13875
uniprot id: A0A3S6F2U0
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

935293:PL78 RS17735
gene id: 935293:PL78_RS17735
uniprot id: A0A3S6F4N5
names: Function
names: Similarity
messages: Belongs to the FliK family.
messages: Controls the length of the flagellar hook.

935293:PL78 RS06470
gene id: 935293:PL78_RS06470
uniprot id: A0A3S6EYB9
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

935293:PL78 RS14105
gene id: 935293:PL78_RS14105
uniprot id: A0A3S6F2P6
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS10275
gene id: 935293:PL78_RS10275
uniprot id: A0A3S6F0I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

935293:PL78 RS01210
gene id: 935293:PL78_RS01210
uniprot id: A0A3S6EX36
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

935293:PL78 RS13045
gene id: 935293:PL78_RS13045
uniprot id: A0A3S6F1Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

935293:PL78 RS08080
gene id: 935293:PL78_RS08080
uniprot id: A0A3S6F0A2
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS11890
gene id: 935293:PL78_RS11890
uniprot id: A0A3S6F1S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. Pit subfamily.
messages: Membrane

935293:PL78 RS13140
gene id: 935293:PL78_RS13140
uniprot id: A0A3S6F203
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

935293:PL78 RS06685
gene id: 935293:PL78_RS06685
uniprot id: A0A3S6EYH1
names: Similarity
messages: Belongs to the YkuD family.

935293:PL78 RS11335
gene id: 935293:PL78_RS11335
uniprot id: A0A3S6F1E7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

935293:PL78 RS18305
gene id: 935293:PL78_RS18305
uniprot id: A0A3S6F580
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

935293:PL78 RS07990
gene id: 935293:PL78_RS07990
uniprot id: A0A3S6EZE1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

935293:PL78 RS18600
gene id: 935293:PL78_RS18600
uniprot id: A0A3S6F6W6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably functions as a manganese efflux pump.

935293:PL78 RS07095
gene id: 935293:PL78_RS07095
uniprot id: A0A3S6EYN1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS10280
gene id: 935293:PL78_RS10280
uniprot id: A0A3S6F1I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Membrane

935293:PL78 RS12810
gene id: 935293:PL78_RS12810
uniprot id: A0A3S6F2W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

935293:PL78 RS08455
gene id: 935293:PL78_RS08455
uniprot id: A0A3S6EZD8
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

935293:PL78 RS08195
gene id: 935293:PL78_RS08195
uniprot id: A0A3S6EZQ2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

935293:PL78 RS04530
gene id: 935293:PL78_RS04530
uniprot id: A0A3S6EYX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtI subfamily.
messages: Catalyzes the excretion of spermidine.
messages: Cell membrane
messages: Forms a complex with MdtJ.
messages: Membrane

935293:PL78 RS15205
gene id: 935293:PL78_RS15205
uniprot id: A0A3S6F3D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

935293:PL78 RS13165
gene id: 935293:PL78_RS13165
uniprot id: A0A3S6F216
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS00685
gene id: 935293:PL78_RS00685
uniprot id: A0A3S6EVB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

935293:PL78 RS09500
gene id: 935293:PL78_RS09500
uniprot id: A0A3S6EZZ5
names: Similarity
messages: Belongs to the UPF0235 family.

935293:PL78 RS09485
gene id: 935293:PL78_RS09485
uniprot id: A0A3S6F034
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Monomer.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

935293:PL78 RS07275
gene id: 935293:PL78_RS07275
uniprot id: A0A3S6EZV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

935293:PL78 RS12120
gene id: 935293:PL78_RS12120
uniprot id: A0A3S6F2J7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

935293:PL78 RS14735
gene id: 935293:PL78_RS14735
uniprot id: A0A3S6F2W5
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS15475
gene id: 935293:PL78_RS15475
uniprot id: A0A3S6F4X1
names: Cofactor
names: Function
messages: Binds 1 [2Fe-2S] cluster.
messages: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.

935293:PL78 RS02295
gene id: 935293:PL78_RS02295
uniprot id: A0A3S6EW17
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Equilibrium between an active dimeric form, an inactive hexameric form and higher aggregates. Interconversion between the various forms is largely reversible and is influenced by the natural substrates and inhibitors of the enzyme.
messages: Feedback inhibited by histidine.

935293:PL78 RS02565
gene id: 935293:PL78_RS02565
uniprot id: A0A3S6EWE2
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS02145
gene id: 935293:PL78_RS02145
uniprot id: A0A3S6EVY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system.

935293:PL78 RS17890
gene id: 935293:PL78_RS17890
uniprot id: A0A3S6F4V4
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.

935293:PL78 RS05325
gene id: 935293:PL78_RS05325
uniprot id: A0A3S6EXY2
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

935293:PL78 RS10525
gene id: 935293:PL78_RS10525
uniprot id: A0A3S6F0M9
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS03960
gene id: 935293:PL78_RS03960
uniprot id: A0A3S6EXC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

935293:PL78 RS02185
gene id: 935293:PL78_RS02185
uniprot id: A0A3S6EXL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0299 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

935293:PL78 RS05020
gene id: 935293:PL78_RS05020
uniprot id: A0A3S6EXS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

935293:PL78 RS06980
gene id: 935293:PL78_RS06980
uniprot id: A0A3S6EYZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

935293:PL78 RS15035
gene id: 935293:PL78_RS15035
uniprot id: A0A3S6F355
names: Similarity
messages: Belongs to the MQO family.

935293:PL78 RS14340
gene id: 935293:PL78_RS14340
uniprot id: A0A3S6F2Q7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
messages: Homodimer.

935293:PL78 RS13930
gene id: 935293:PL78_RS13930
uniprot id: A0A3S6F417
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

935293:PL78 RS18795
gene id: 935293:PL78_RS18795
uniprot id: A0A3S6F5K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ivy family.
messages: Periplasm

935293:PL78 RS15005
gene id: 935293:PL78_RS15005
uniprot id: A0A3S6F3C5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS04850
gene id: 935293:PL78_RS04850
uniprot id: A0A3S6EXI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

935293:PL78 RS18505
gene id: 935293:PL78_RS18505
uniprot id: A0A3S6F5E8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS01775
gene id: 935293:PL78_RS01775
uniprot id: A0A3S6EW55
names: Similarity
messages: Belongs to the MoaD family.

935293:PL78 RS17445
gene id: 935293:PL78_RS17445
uniprot id: A0A3S6F4F3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtfA family.
messages: Cytoplasm
messages: Interacts with Mlc.
messages: Involved in the regulation of ptsG expression by binding and inactivating Mlc.

935293:PL78 RS01685
gene id: 935293:PL78_RS01685
uniprot id: A0A3S6EVN6
names: Function
names: Similarity
messages: Belongs to the cycloisomerase 2 family.
messages: Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

935293:PL78 RS13605
gene id: 935293:PL78_RS13605
uniprot id: A0A3S6F2E5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

935293:PL78 RS12775
gene id: 935293:PL78_RS12775
uniprot id: A0A3S6F263
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

935293:PL78 RS16610
gene id: 935293:PL78_RS16610
uniprot id: A0A3S6F3Z4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

935293:PL78 RS00465
gene id: 935293:PL78_RS00465
uniprot id: A0A3S6EW45
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

935293:PL78 RS01790
gene id: 935293:PL78_RS01790
uniprot id: A0A3S6EVQ7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

935293:PL78 RS14420
gene id: 935293:PL78_RS14420
uniprot id: A0A3S6F2Q1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS10550
gene id: 935293:PL78_RS10550
uniprot id: A0A3S6F103
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

935293:PL78 RS03710
gene id: 935293:PL78_RS03710
uniprot id: B6A870
names: Subcellular Location Annotation
messages: Cell inner membrane

935293:PL78 RS14185
gene id: 935293:PL78_RS14185
uniprot id: A0A3S6F2J8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

935293:PL78 RS06815
gene id: 935293:PL78_RS06815
uniprot id: A0A3S6EYJ2
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

935293:PL78 RS01590
gene id: 935293:PL78_RS01590
uniprot id: A0A3S6EVL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

935293:PL78 RS01780
gene id: 935293:PL78_RS01780
uniprot id: A0A3S6EXD4
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

935293:PL78 RS01740
gene id: 935293:PL78_RS01740
uniprot id: A0A3S6EVP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

935293:PL78 RS13845
gene id: 935293:PL78_RS13845
uniprot id: A0A3S6F2H8
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

935293:PL78 RS15895
gene id: 935293:PL78_RS15895
uniprot id: A0A3S6F3M4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

935293:PL78 RS14260
gene id: 935293:PL78_RS14260
uniprot id: A0A3S6F2V9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

935293:PL78 RS13110
gene id: 935293:PL78_RS13110
uniprot id: A0A3S6F207
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

935293:PL78 RS18815
gene id: 935293:PL78_RS18815
uniprot id: A0A3S6F595
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

935293:PL78 RS01970
gene id: 935293:PL78_RS01970
uniprot id: A0A3S6EVT3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

935293:PL78 RS12520
gene id: 935293:PL78_RS12520
uniprot id: A0A3S6F1S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

935293:PL78 RS18595
gene id: 935293:PL78_RS18595
uniprot id: A0A3S6F5G7
names: Similarity
messages: Belongs to the bleomycin resistance protein family.

935293:PL78 RS13360
gene id: 935293:PL78_RS13360
uniprot id: A0A3S6F243
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

935293:PL78 RS02670
gene id: 935293:PL78_RS02670
uniprot id: A0A3S6EWQ6
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS02730
gene id: 935293:PL78_RS02730
uniprot id: A0A3S6EWP3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family. MukB subfamily.
messages: Homodimerization via its hinge domain. Binds to DNA via its C-terminal region. Interacts, and probably forms a ternary complex, with MukE and MukF via its C-terminal region. The complex formation is stimulated by calcium or magnesium. Interacts with tubulin-related protein FtsZ.
messages: Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
messages: The hinge domain, which separates the large intramolecular coiled coil regions, allows the homodimerization, forming a V-shaped homodimer.
messages: nucleoid

935293:PL78 RS17555
gene id: 935293:PL78_RS17555
uniprot id: A0A3S6F4W4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhC family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.

935293:PL78 RS18640
gene id: 935293:PL78_RS18640
uniprot id: A0A3S6F534
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

935293:PL78 RS06935
gene id: 935293:PL78_RS06935
uniprot id: A0A3S6EYP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NusG family.
messages: Monomer. Interacts with the transcription termination factor Rho and with RNA polymerase.
messages: Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination.

935293:PL78 RS11165
gene id: 935293:PL78_RS11165
uniprot id: A0A3S6F110
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

935293:PL78 RS11850
gene id: 935293:PL78_RS11850
uniprot id: A0A3S6F2Y2
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

935293:PL78 RS14990
gene id: 935293:PL78_RS14990
uniprot id: A0A3S6F432
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Asr family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Periplasm
messages: Proteolytic processing gives rise to the active protein.
messages: Required for growth and/or survival at acidic conditions.

935293:PL78 RS00580
gene id: 935293:PL78_RS00580
uniprot id: A0A3S6EV95
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

935293:PL78 RS07870
gene id: 935293:PL78_RS07870
uniprot id: A0A3S6EZ45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapB family.
messages: Cytoplasm
messages: Homodimer. The ends of the coiled-coil dimer bind to each other, forming polymers. Interacts with FtsZ.
messages: Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.

935293:PL78 RS18680
gene id: 935293:PL78_RS18680
uniprot id: A0A3S6F5A0
names: Function
names: Similarity
messages: Belongs to the N(4)-acetylcytidine amidohydrolase family.
messages: Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C).

935293:PL78 RS06715
gene id: 935293:PL78_RS06715
uniprot id: A0A3S6EYY7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

935293:PL78 RS16695
gene id: 935293:PL78_RS16695
uniprot id: A0A3S6F445
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 30 kDa subunit family.
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

935293:PL78 RS18240
gene id: 935293:PL78_RS18240
uniprot id: A0A3S6F5Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YscJ lipoprotein family.
messages: Cell outer membrane
messages: Membrane

935293:PL78 RS14440
gene id: 935293:PL78_RS14440
uniprot id: A0A3S6F2U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

935293:PL78 RS14945
gene id: 935293:PL78_RS14945
uniprot id: A0A3S6F357
names: Similarity
messages: Belongs to the ABC transporter superfamily.

935293:PL78 RS03200
gene id: 935293:PL78_RS03200
uniprot id: A0A3S6EWL6
names: Function
names: Similarity
messages: Belongs to the thiamine kinase family.
messages: Catalyzes the phosphorylation of thiamine to thiamine phosphate.

935293:PL78 RS08365
gene id: 935293:PL78_RS08365
uniprot id: A0A3S6EZC7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CutA family.
messages: Binds 1 copper ion per subunit.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in resistance toward heavy metals.

935293:PL78 RS11235
gene id: 935293:PL78_RS11235
uniprot id: A0A3S6F1C7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

935293:PL78 RS12585
gene id: 935293:PL78_RS12585
uniprot id: A0A3S6F1Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

935293:PL78 RS16685
gene id: 935293:PL78_RS16685
uniprot id: A0A3S6F435
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

935293:PL78 RS00780
gene id: 935293:PL78_RS00780
uniprot id: A0A3S6EV67
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

935293:PL78 RS04915
gene id: 935293:PL78_RS04915
uniprot id: A0A3S6EXI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Homodimer. Forms a complex with the accessory proteins ExbB and ExbD.
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

935293:PL78 RS01840
gene id: 935293:PL78_RS01840
uniprot id: A0A3S6EVR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinone-dependent D-lactate dehydrogenase family.
messages: Catalyzes the oxidation of D-lactate to pyruvate.
messages: Cell inner membrane

935293:PL78 RS12530
gene id: 935293:PL78_RS12530
uniprot id: A0A3S6F1T3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

935293:PL78 RS17845
gene id: 935293:PL78_RS17845
uniprot id: A0A3S6F4Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS01225
gene id: 935293:PL78_RS01225
uniprot id: A0A3S6EVG3
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

935293:PL78 RS13745
gene id: 935293:PL78_RS13745
uniprot id: A0A3S6F2G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

935293:PL78 RS06555
gene id: 935293:PL78_RS06555
uniprot id: A0A3S6EYH9
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS01140
gene id: 935293:PL78_RS01140
uniprot id: A0A3S6EVK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

935293:PL78 RS05040
gene id: 935293:PL78_RS05040
uniprot id: A0A3S6EZ75
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: Homodimer.

935293:PL78 RS19025
gene id: 935293:PL78_RS19025
uniprot id: A0A3S6F5D9
names: Similarity
messages: Belongs to the transglycosylase Slt family.

935293:PL78 RS04695
gene id: 935293:PL78_RS04695
uniprot id: A0A3S6EXD6
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

935293:PL78 RS01445
gene id: 935293:PL78_RS01445
uniprot id: A0A3S6EVJ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

935293:PL78 RS12925
gene id: 935293:PL78_RS12925
uniprot id: A0A3S6F291
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

935293:PL78 RS11185
gene id: 935293:PL78_RS11185
uniprot id: A0A3S6F1B7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

935293:PL78 RS04605
gene id: 935293:PL78_RS04605
uniprot id: A0A3S6EXC3
names: Similarity
messages: Belongs to the UPF0260 family.

935293:PL78 RS00770
gene id: 935293:PL78_RS00770
uniprot id: A0A3S6EV62
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS11260
gene id: 935293:PL78_RS11260
uniprot id: A0A3S6F106
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

935293:PL78 RS14205
gene id: 935293:PL78_RS14205
uniprot id: A0A3S6F2R4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine.

935293:PL78 RS06660
gene id: 935293:PL78_RS06660
uniprot id: A0A3S6EYP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

935293:PL78 RS16790
gene id: 935293:PL78_RS16790
uniprot id: A0A3S6F533
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

935293:PL78 RS03020
gene id: 935293:PL78_RS03020
uniprot id: A0A3S6EWM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-lipid IV(A) to form a Kdo(2)-(acyl)-lipid IV(A).
messages: Cell inner membrane

935293:PL78 RS10780
gene id: 935293:PL78_RS10780
uniprot id: A0A3S6F0T4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

935293:PL78 RS09445
gene id: 935293:PL78_RS09445
uniprot id: A0A3S6F0D0
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

935293:PL78 RS03900
gene id: 935293:PL78_RS03900
uniprot id: A0A3S6EXF0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

935293:PL78 RS07180
gene id: 935293:PL78_RS07180
uniprot id: A0A3S6EYT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

935293:PL78 RS10700
gene id: 935293:PL78_RS10700
uniprot id: A0A3S6F127
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
messages: Cell membrane
messages: Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS14050
gene id: 935293:PL78_RS14050
uniprot id: A0A3S6F3L2
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

935293:PL78 RS04500
gene id: 935293:PL78_RS04500
uniprot id: A0A3S6EYC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family. LpxM subfamily.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-(acyl)-lipid IV(A) to form a Kdo(2)-lipid A.
messages: Cell inner membrane

935293:PL78 RS09845
gene id: 935293:PL78_RS09845
uniprot id: A0A3S6F0G8
names: Subunit
messages: Monomer.

935293:PL78 RS04445
gene id: 935293:PL78_RS04445
uniprot id: A0A3S6EX83
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS17630
gene id: 935293:PL78_RS17630
uniprot id: A0A3S6F5J8
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

935293:PL78 RS02875
gene id: 935293:PL78_RS02875
uniprot id: A0A3S6EWC3
names: Subcellular Location Annotation
messages: Cell inner membrane

935293:PL78 RS05815
gene id: 935293:PL78_RS05815
uniprot id: A0A3S6EY26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxine kinase family. PdxY subfamily.
messages: Homodimer.
messages: Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.

935293:PL78 RS06765
gene id: 935293:PL78_RS06765
uniprot id: A0A3S6EYR2
names: Similarity
messages: Belongs to the transglycosylase Slt family.

935293:PL78 RS05495
gene id: 935293:PL78_RS05495
uniprot id: A0A3S6EY63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

935293:PL78 RS05965
gene id: 935293:PL78_RS05965
uniprot id: A0A3S6EY56
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Multidrug efflux pump that functions probably as a Na(+)/drug antiporter.

935293:PL78 RS11865
gene id: 935293:PL78_RS11865
uniprot id: A0A3S6F1E9
names: Similarity
messages: Belongs to the pirin family.

935293:PL78 RS19000
gene id: 935293:PL78_RS19000
uniprot id: A0A3S6F790
names: Similarity
messages: Belongs to the fructosamine kinase family.

935293:PL78 RS05035
gene id: 935293:PL78_RS05035
uniprot id: A0A3S6EXY4
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

935293:PL78 RS15775
gene id: 935293:PL78_RS15775
uniprot id: A0A3S6F3W2
names: Similarity
messages: Belongs to the ArsC family.

935293:PL78 RS02065
gene id: 935293:PL78_RS02065
uniprot id: A0A3S6EW41
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS09965
gene id: 935293:PL78_RS09965
uniprot id: A0A3S6F074
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

935293:PL78 RS07705
gene id: 935293:PL78_RS07705
uniprot id: A0A3S6EZC4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.
messages: Cell outer membrane
messages: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

935293:PL78 RS18470
gene id: 935293:PL78_RS18470
uniprot id: A0A3S6F519
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

935293:PL78 RS09025
gene id: 935293:PL78_RS09025
uniprot id: A0A3S6F0T6
names: Similarity
messages: Belongs to the RecJ family.

935293:PL78 RS02645
gene id: 935293:PL78_RS02645
uniprot id: A0A3S6EW91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

935293:PL78 RS13635
gene id: 935293:PL78_RS13635
uniprot id: A0A3S6F294
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS11180
gene id: 935293:PL78_RS11180
uniprot id: A0A3S6F160
names: Similarity
messages: Belongs to the DprA/Smf family.

935293:PL78 RS00820
gene id: 935293:PL78_RS00820
uniprot id: A0A3S6EV73
names: Similarity
messages: Belongs to the band 7/mec-2 family.

935293:PL78 RS12260
gene id: 935293:PL78_RS12260
uniprot id: A0A3S6F1I4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

935293:PL78 RS14090
gene id: 935293:PL78_RS14090
uniprot id: A0A3S6F2K7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

935293:PL78 RS16915
gene id: 935293:PL78_RS16915
uniprot id: A0A3S6F4I9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

935293:PL78 RS15435
gene id: 935293:PL78_RS15435
uniprot id: A0A3S6F3D6
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Consists of two distinct domains; an N-terminal heme-containing oxygen-binding domain and a C-terminal reductase domain with binding sites for FAD and NAD(P)H.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS07620
gene id: 935293:PL78_RS07620
uniprot id: A0A3S6EZB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

935293:PL78 RS16370
gene id: 935293:PL78_RS16370
uniprot id: A0A3S6F5D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

935293:PL78 RS13205
gene id: 935293:PL78_RS13205
uniprot id: A0A3S6F3N0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

935293:PL78 RS12085
gene id: 935293:PL78_RS12085
uniprot id: A0A3S6F1T8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS13030
gene id: 935293:PL78_RS13030
uniprot id: A0A3S6F1Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

935293:PL78 RS15995
gene id: 935293:PL78_RS15995
uniprot id: A0A3S6F3P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sialate:H(+) symporter (SHS) (TC 2.A.1.12) family.
messages: Catalyzes the proton-dependent transport of sialic acid.
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS07850
gene id: 935293:PL78_RS07850
uniprot id: A0A3S6EZ24
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

935293:PL78 RS06855
gene id: 935293:PL78_RS06855
uniprot id: A0A3S6EYW9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Divalent metal cations. Mg(2+) or Mn(2+).
messages: Homodimer.
messages: mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing. Has preference for mRNAs with a 5'-end purine. Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.

935293:PL78 RS18890
gene id: 935293:PL78_RS18890
uniprot id: A0A3S6F594
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PqiA family.
messages: Component of a transport pathway that contributes to membrane integrity.
messages: Membrane

935293:PL78 RS12870
gene id: 935293:PL78_RS12870
uniprot id: A0A3S6F238
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

935293:PL78 RS10490
gene id: 935293:PL78_RS10490
uniprot id: A0A3S6F0N2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

935293:PL78 RS06905
gene id: 935293:PL78_RS06905
uniprot id: A0A3S6EYY0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

935293:PL78 RS13125
gene id: 935293:PL78_RS13125
uniprot id: A0A3S6F252
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

935293:PL78 RS09495
gene id: 935293:PL78_RS09495
uniprot id: A0A3S6F0E1
names: Similarity
messages: Belongs to the YggT family.

935293:PL78 RS13555
gene id: 935293:PL78_RS13555
uniprot id: A0A3S6F2H1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS12235
gene id: 935293:PL78_RS12235
uniprot id: A0A3S6F1R5
names: Cofactor
names: Function
messages: Binds 4 [4Fe-4S] clusters per subunit.
messages: The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.

935293:PL78 RS00515
gene id: 935293:PL78_RS00515
uniprot id: A0A3S6EW56
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS14375
gene id: 935293:PL78_RS14375
uniprot id: A0A3S6F342
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS04470
gene id: 935293:PL78_RS04470
uniprot id: A0A3S6EX93
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

935293:PL78 RS10475
gene id: 935293:PL78_RS10475
uniprot id: A0A3S6F0L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZapG family.
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS17700
gene id: 935293:PL78_RS17700
uniprot id: A0A3S6F4K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

935293:PL78 RS01310
gene id: 935293:PL78_RS01310
uniprot id: A0A3S6EWK4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

935293:PL78 RS07250
gene id: 935293:PL78_RS07250
uniprot id: A0A3S6EZ39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PanZ/PanM family.
messages: Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion.
messages: Interacts with PanD in the presence of CoA.

935293:PL78 RS02780
gene id: 935293:PL78_RS02780
uniprot id: A0A3S6EWQ4
names: Similarity
messages: Belongs to the peptidase M1 family.

935293:PL78 RS07485
gene id: 935293:PL78_RS07485
uniprot id: A0A3S6EZ50
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

935293:PL78 RS16780
gene id: 935293:PL78_RS16780
uniprot id: A0A3S6F436
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

935293:PL78 RS08580
gene id: 935293:PL78_RS08580
uniprot id: A0A3S6EZV3
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

935293:PL78 RS09625
gene id: 935293:PL78_RS09625
uniprot id: A0A3S6F043
names: Similarity
messages: Belongs to the delta endotoxin family.

935293:PL78 RS13760
gene id: 935293:PL78_RS13760
uniprot id: A0A3S6F2L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

935293:PL78 RS14670
gene id: 935293:PL78_RS14670
uniprot id: B6A8B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

935293:PL78 RS04765
gene id: 935293:PL78_RS04765
uniprot id: A0A3S6EXW6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Binds two Mg(2+) per subunit.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

935293:PL78 RS11310
gene id: 935293:PL78_RS11310
uniprot id: A0A3S6F115
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

935293:PL78 RS19005
gene id: 935293:PL78_RS19005
uniprot id: A0A3S6F585
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS13290
gene id: 935293:PL78_RS13290
uniprot id: A0A3S6F2F5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS01535
gene id: 935293:PL78_RS01535
uniprot id: A0A3S6EW15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

935293:PL78 RS16425
gene id: 935293:PL78_RS16425
uniprot id: A0A3S6F3S6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

935293:PL78 RS14760
gene id: 935293:PL78_RS14760
uniprot id: A0A3S6F306
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

935293:PL78 RS01995
gene id: 935293:PL78_RS01995
uniprot id: A0A3S6EVV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS03310
gene id: 935293:PL78_RS03310
uniprot id: A0A3S6EWL1
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

935293:PL78 RS00325
gene id: 935293:PL78_RS00325
uniprot id: A0A3S6EV41
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

935293:PL78 RS17095
gene id: 935293:PL78_RS17095
uniprot id: A0A3S6F499
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS11935
gene id: 935293:PL78_RS11935
uniprot id: A0A3S6F1C1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

935293:PL78 RS00740
gene id: 935293:PL78_RS00740
uniprot id: A0A3S6EVM2
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS02450
gene id: 935293:PL78_RS02450
uniprot id: A0A3S6EW58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

935293:PL78 RS15785
gene id: 935293:PL78_RS15785
uniprot id: A0A3S6F3F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

935293:PL78 RS15290
gene id: 935293:PL78_RS15290
uniprot id: A0A3S6F3A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

935293:PL78 RS00280
gene id: 935293:PL78_RS00280
uniprot id: A0A3S6EVC5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

935293:PL78 RS02095
gene id: 935293:PL78_RS02095
uniprot id: A0A3S6EVX5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

935293:PL78 RS05480
gene id: 935293:PL78_RS05480
uniprot id: A0A3S6EY02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

935293:PL78 RS06665
gene id: 935293:PL78_RS06665
uniprot id: A0A3S6EYX7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

935293:PL78 RS18430
gene id: 935293:PL78_RS18430
uniprot id: A0A3S6F648
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

935293:PL78 RS06020
gene id: 935293:PL78_RS06020
uniprot id: A0A3S6EY45
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

935293:PL78 RS11275
gene id: 935293:PL78_RS11275
uniprot id: A0A3S6F135
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

935293:PL78 RS01460
gene id: 935293:PL78_RS01460
uniprot id: A0A3S6EWM3
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

935293:PL78 RS06200
gene id: 935293:PL78_RS06200
uniprot id: A0A3S6EYE9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

935293:PL78 RS09080
gene id: 935293:PL78_RS09080
uniprot id: A0A3S6EZU9
names: Subunit
messages: Homodimer.

935293:PL78 RS11080
gene id: 935293:PL78_RS11080
uniprot id: A0A3S6F101
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPS (TC 1.B.20) family.
messages: Cell outer membrane
messages: Membrane

935293:PL78 RS13915
gene id: 935293:PL78_RS13915
uniprot id: A0A3S6F2S5
names: Caution
names: Function
messages: Activates the small RNA gene sgrS under glucose-phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS18195
gene id: 935293:PL78_RS18195
uniprot id: A0A3S6F4X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SctE/SipB/YopB family.
messages: Host membrane
messages: Secreted

935293:PL78 RS10745
gene id: 935293:PL78_RS10745
uniprot id: A0A3S6F0Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

935293:PL78 RS18710
gene id: 935293:PL78_RS18710
uniprot id: A0A3S6F574
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

935293:PL78 RS09325
gene id: 935293:PL78_RS09325
uniprot id: A0A3S6EZY8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

935293:PL78 RS01485
gene id: 935293:PL78_RS01485
uniprot id: A0A3S6EW03
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

935293:PL78 RS13670
gene id: 935293:PL78_RS13670
uniprot id: A0A3S6F2A2
names: Similarity
messages: Belongs to the transglycosylase Slt family.

935293:PL78 RS16590
gene id: 935293:PL78_RS16590
uniprot id: A0A3S6F4Z0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

935293:PL78 RS19010
gene id: 935293:PL78_RS19010
uniprot id: A0A3S6F5D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS14600
gene id: 935293:PL78_RS14600
uniprot id: A0A3S6F2Z3
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

935293:PL78 RS11785
gene id: 935293:PL78_RS11785
uniprot id: A0A3S6F1N1
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by ATP and maltotriose, which are both required for DNA binding.
messages: Belongs to the MalT family.
messages: Monomer in solution. Oligomerizes to an active state in the presence of the positive effectors ATP and maltotriose.
messages: Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.

935293:PL78 RS13870
gene id: 935293:PL78_RS13870
uniprot id: A0A3S6F2E4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

935293:PL78 RS07420
gene id: 935293:PL78_RS07420
uniprot id: A0A3S6EYX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

935293:PL78 RS08800
gene id: 935293:PL78_RS08800
uniprot id: A0A3S6F164
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: Homohexamer.

935293:PL78 RS15680
gene id: 935293:PL78_RS15680
uniprot id: A0A3S6F512
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS03180
gene id: 935293:PL78_RS03180
uniprot id: A0A3S6EWJ4
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS05915
gene id: 935293:PL78_RS05915
uniprot id: A0A3S6EY47
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

935293:PL78 RS03980
gene id: 935293:PL78_RS03980
uniprot id: A0A3S6EWZ4
names: Similarity
messages: Belongs to the IucA/IucC family.

935293:PL78 RS18070
gene id: 935293:PL78_RS18070
uniprot id: A0A3S6F6E2
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

935293:PL78 RS10300
gene id: 935293:PL78_RS10300
uniprot id: A0A3S6F0F9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

935293:PL78 RS07090
gene id: 935293:PL78_RS07090
uniprot id: A0A3S6EZ49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

935293:PL78 RS05715
gene id: 935293:PL78_RS05715
uniprot id: A0A3S6EXZ3
names: Similarity
messages: Belongs to the arginase family.

935293:PL78 RS12070
gene id: 935293:PL78_RS12070
uniprot id: A0A3S6F2I4
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS16065
gene id: 935293:PL78_RS16065
uniprot id: A0A3S6F3Y7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

935293:PL78 RS13785
gene id: 935293:PL78_RS13785
uniprot id: A0A3S6F2C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

935293:PL78 RS15480
gene id: 935293:PL78_RS15480
uniprot id: A0A3S6F3A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

935293:PL78 RS07115
gene id: 935293:PL78_RS07115
uniprot id: A0A3S6EYQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS08325
gene id: 935293:PL78_RS08325
uniprot id: A0A3S6EZE6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

935293:PL78 RS00860
gene id: 935293:PL78_RS00860
uniprot id: A0A3S6EV77
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

935293:PL78 RS03255
gene id: 935293:PL78_RS03255
uniprot id: A0A3S6EWK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

935293:PL78 RS13310
gene id: 935293:PL78_RS13310
uniprot id: A0A3S6F234
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS02560
gene id: 935293:PL78_RS02560
uniprot id: A0A3S6EW77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

935293:PL78 RS11750
gene id: 935293:PL78_RS11750
uniprot id: A0A3S6F2W3
names: Function
names: Similarity
messages: Belongs to the FeoC family.
messages: May function as a transcriptional regulator that controls feoABC expression.

935293:PL78 RS03670
gene id: 935293:PL78_RS03670
uniprot id: A0A3S6EWU7
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

935293:PL78 RS05280
gene id: 935293:PL78_RS05280
uniprot id: A0A3S6EY61
names: Similarity
messages: Belongs to the UPF0482 family.

935293:PL78 RS08265
gene id: 935293:PL78_RS08265
uniprot id: A0A3S6EZB0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).

935293:PL78 RS10465
gene id: 935293:PL78_RS10465
uniprot id: A0A3S6F259
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

935293:PL78 RS07395
gene id: 935293:PL78_RS07395
uniprot id: A0A3S6EYU1
names: Similarity
messages: Belongs to the Rht family.

935293:PL78 RS02440
gene id: 935293:PL78_RS02440
uniprot id: A0A3S6EW43
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.

935293:PL78 RS12895
gene id: 935293:PL78_RS12895
uniprot id: A0A3S6F1V5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PriB family.
messages: Binds single-stranded DNA at the primosome assembly site (PAS).
messages: Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome.

935293:PL78 RS04310
gene id: 935293:PL78_RS04310
uniprot id: A0A3S6EXM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

935293:PL78 RS11625
gene id: 935293:PL78_RS11625
uniprot id: A0A3S6F1A5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DamX family.
messages: Cell inner membrane
messages: Non-essential cell division protein.
messages: The SPOR domain binds septal peptidoglycans and is required to target DamX to the septal ring.

935293:PL78 RS00805
gene id: 935293:PL78_RS00805
uniprot id: A0A3S6EWV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

935293:PL78 RS06945
gene id: 935293:PL78_RS06945
uniprot id: A0A3S6EZ28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

935293:PL78 RS13505
gene id: 935293:PL78_RS13505
uniprot id: A0A3S6F2L8
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

935293:PL78 RS01820
gene id: 935293:PL78_RS01820
uniprot id: A0A3S6EVQ2
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.

935293:PL78 RS03540
gene id: 935293:PL78_RS03540
uniprot id: A0A3S6EX46
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

935293:PL78 RS07975
gene id: 935293:PL78_RS07975
uniprot id: A0A3S6EZ73
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

935293:PL78 RS14305
gene id: 935293:PL78_RS14305
uniprot id: A0A3S6F2T4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

935293:PL78 RS13175
gene id: 935293:PL78_RS13175
uniprot id: A0A3S6F346
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiV subfamily.
messages: Forms an heterodimer with UbiU.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

935293:PL78 RS18715
gene id: 935293:PL78_RS18715
uniprot id: A0A3S6F577
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopC family.
messages: Involved in copper resistance.
messages: Periplasm

935293:PL78 RS04705
gene id: 935293:PL78_RS04705
uniprot id: A0A3S6EXE4
names: Similarity
messages: Belongs to the UPF0229 family.

935293:PL78 RS12055
gene id: 935293:PL78_RS12055
uniprot id: A0A3S6F1G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS11330
gene id: 935293:PL78_RS11330
uniprot id: A0A3S6F192
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

935293:PL78 RS07725
gene id: 935293:PL78_RS07725
uniprot id: A0A3S6EZ23
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
messages: Cytoplasm

935293:PL78 RS01110
gene id: 935293:PL78_RS01110
uniprot id: A0A3S6EX17
names: Similarity
messages: Belongs to the UPF0250 family.

935293:PL78 RS10825
gene id: 935293:PL78_RS10825
uniprot id: A0A3S6F0T9
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

935293:PL78 RS11305
gene id: 935293:PL78_RS11305
uniprot id: A0A3S6F0Y7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

935293:PL78 RS12580
gene id: 935293:PL78_RS12580
uniprot id: A0A3S6F1U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

935293:PL78 RS05075
gene id: 935293:PL78_RS05075
uniprot id: A0A3S6EY24
names: Similarity
messages: Belongs to the SUI1 family.

935293:PL78 RS02510
gene id: 935293:PL78_RS02510
uniprot id: A0A3S6EW66
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

935293:PL78 RS02625
gene id: 935293:PL78_RS02625
uniprot id: A0A3S6EW71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

935293:PL78 RS05195
gene id: 935293:PL78_RS05195
uniprot id: A0A3S6EXN8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.

935293:PL78 RS05950
gene id: 935293:PL78_RS05950
uniprot id: A0A3S6EZN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS03380
gene id: 935293:PL78_RS03380
uniprot id: A0A3S6EX43
names: Similarity
messages: Belongs to the HsdR family.

935293:PL78 RS14620
gene id: 935293:PL78_RS14620
uniprot id: A0A3S6F394
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Membrane

935293:PL78 RS08355
gene id: 935293:PL78_RS08355
uniprot id: A0A3S6EZR1
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

935293:PL78 RS17870
gene id: 935293:PL78_RS17870
uniprot id: A0A3S6F4P8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DyP-type peroxidase family. EfeB subfamily.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Homodimer. Part of a ferrous iron transporter composed of EfeU, EfeO and EfeB.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.
messages: Periplasm

935293:PL78 RS07555
gene id: 935293:PL78_RS07555
uniprot id: A0A3S6EZ62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily.
messages: Catalyzes the four-electron oxidation of UDP-N-acetyl-D-mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N-acetylmannosaminuronic acid (UDP-ManNAcA).
messages: Homodimer.

935293:PL78 RS11775
gene id: 935293:PL78_RS11775
uniprot id: A0A3S6F1D5
names: Similarity
messages: Belongs to the disproportionating enzyme family.

935293:PL78 RS15470
gene id: 935293:PL78_RS15470
uniprot id: A0A3S6F3Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

935293:PL78 RS03780
gene id: 935293:PL78_RS03780
uniprot id: A0A3S6EX30
uniprot id: B6A880
names: Activity Regulation
names: Disruption Phenotype
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cells with a disrupted yenA1-yenA2-chi2-yenB-yenC1-yenC2 locus are no longer pathogenic in C.zealandica larvae.
messages: In the N-terminal section; belongs to the SpvB family.
messages: Part of an orally active toxin complex (TC) with strong insecticidal effects on larvae of the Coleoptera Costelytra zealandica, Acrossidius tasmania and Adoryphorus couloni and some Lepidoptera larvae (PubMed:21278295, PubMed:22158901). The TC has an endochitinase activity (PubMed:21278295) (Probable).
messages: Residues 389-698 form a 5-bladed beta-propeller domain which closes one end of the shell; the other end of the shell is closed by the RHS repeat-associated core domain in YenC2.
messages: Secreted
messages: Semipurified toxin complex consists of at least YenA1-YenA2-YenB-YenC1-YenC2-Chi1-Chi2 (PubMed:21278295). YenB and the N-terminus of YenC2 form a large hollow shell of beta-strands (PubMed:23913273). The shell is closed at both ends, within which the C-terminus of YenC2 is probably found (PubMed:23913273). The Yen-TC:K9 subcomplex is about 26 nm tall and 22 nm in diameter with 5-fold symmetry and 5 copies of YenA1, YenA2, Chi1 and Chi2; the chitinase subunits may be solvent accessible on the exterior the complex (PubMed:22158901). The Yen-TC:K9 subcomplex has no insecticidal activity (PubMed:22158901). The native complex with additional YenB, YenC1 and YenC2 subunits is 16 nm taller and is insecticidal; the toxicity-conferring subunits are present at about 1 copy each (PubMed:22158901).
messages: Toxin complex is secreted when grown at 25 degrees Celsius or less; at higher temperatures the proteins are present intracellularly but not secreted.

935293:PL78 RS14230
gene id: 935293:PL78_RS14230
uniprot id: A0A3S6F480
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

935293:PL78 RS02790
gene id: 935293:PL78_RS02790
uniprot id: A0A3S6EWB8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

935293:PL78 RS02415
gene id: 935293:PL78_RS02415
uniprot id: A0A3S6EWB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

935293:PL78 RS00630
gene id: 935293:PL78_RS00630
uniprot id: A0A3S6EV34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

935293:PL78 RS13755
gene id: 935293:PL78_RS13755
uniprot id: D8UZD5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

935293:PL78 RS02700
gene id: 935293:PL78_RS02700
uniprot id: A0A3S6EWA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

935293:PL78 RS09905
gene id: 935293:PL78_RS09905
uniprot id: A0A3S6F078
names: Function
names: Similarity
names: Subunit
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.
messages: Belongs to the Nudix hydrolase family. NudK subfamily.
messages: Homodimer.
messages: Nucleoside diphosphate sugar hydrolase that hydrolyzes GDP-mannose as its preferred substrate, yielding GMP and mannose-1-phosphate.

935293:PL78 RS09155
gene id: 935293:PL78_RS09155
uniprot id: A0A3S6F066
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LysR transcriptional regulatory family.
messages: Controls the transcription of genes involved in arginine and lysine metabolism.
messages: Homodimer.

935293:PL78 RS13550
gene id: 935293:PL78_RS13550
uniprot id: A0A3S6F2D5
names: Function
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.

935293:PL78 RS08685
gene id: 935293:PL78_RS08685
uniprot id: A0A3S6F144
names: Activity Regulation
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

935293:PL78 RS03115
gene id: 935293:PL78_RS03115
uniprot id: A0A3S6EWI3
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

935293:PL78 RS04880
gene id: 935293:PL78_RS04880
uniprot id: A0A3S6EXH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

935293:PL78 RS04965
gene id: 935293:PL78_RS04965
uniprot id: A0A3S6EXJ2
names: Function
names: Similarity
messages: Belongs to the TrpC family.
messages: Belongs to the TrpF family.
messages: Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.
messages: In the C-terminal section; belongs to the TrpF family.
messages: In the N-terminal section; belongs to the TrpC family.

935293:PL78 RS04690
gene id: 935293:PL78_RS04690
uniprot id: A0A3S6EXF5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS09895
gene id: 935293:PL78_RS09895
uniprot id: A0A3S6F0H8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.

935293:PL78 RS11440
gene id: 935293:PL78_RS11440
uniprot id: A0A3S6F123
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily.
messages: Cell inner membrane
messages: Interacts with KefB.
messages: Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB.

935293:PL78 RS08050
gene id: 935293:PL78_RS08050
uniprot id: A0A3S6EZ60
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS06675
gene id: 935293:PL78_RS06675
uniprot id: A0A3S6EYT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

935293:PL78 RS14175
gene id: 935293:PL78_RS14175
uniprot id: A0A3S6F300
names: Similarity
messages: Belongs to the UPF0231 family.

935293:PL78 RS11620
gene id: 935293:PL78_RS11620
uniprot id: A0A3S6F290
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

935293:PL78 RS05810
gene id: 935293:PL78_RS05810
uniprot id: A0A3S6EY21
names: Similarity
messages: Belongs to the GST superfamily.

935293:PL78 RS04255
gene id: 935293:PL78_RS04255
uniprot id: A0A3S6EXC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

935293:PL78 RS04115
gene id: 935293:PL78_RS04115
uniprot id: A0A3S6EXF4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS01480
gene id: 935293:PL78_RS01480
uniprot id: A0A3S6EVJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

935293:PL78 RS11395
gene id: 935293:PL78_RS11395
uniprot id: A0A3S6F1H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DsrH/TusB family.
messages: Cytoplasm
messages: Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.

935293:PL78 RS09050
gene id: 935293:PL78_RS09050
uniprot id: A0A3S6F047
names: Subcellular Location Annotation
messages: Cell inner membrane

935293:PL78 RS12275
gene id: 935293:PL78_RS12275
uniprot id: A0A3S6F2M4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

935293:PL78 RS01175
gene id: 935293:PL78_RS01175
uniprot id: A0A3S6EVF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS11825
gene id: 935293:PL78_RS11825
uniprot id: A0A3S6F1E6
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.

935293:PL78 RS11675
gene id: 935293:PL78_RS11675
uniprot id: A0A3S6F1B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IgaA family.
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS08965
gene id: 935293:PL78_RS08965
uniprot id: A0A3S6EZR7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

935293:PL78 RS11250
gene id: 935293:PL78_RS11250
uniprot id: A0A3S6F2L3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

935293:PL78 RS08805
gene id: 935293:PL78_RS08805
uniprot id: A0A3S6EZK0
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

935293:PL78 RS15805
gene id: 935293:PL78_RS15805
uniprot id: A0A3S6F3M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamC family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

935293:PL78 RS14415
gene id: 935293:PL78_RS14415
uniprot id: A0A3S6F318
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

935293:PL78 RS10755
gene id: 935293:PL78_RS10755
uniprot id: A0A3S6F0P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

935293:PL78 RS11895
gene id: 935293:PL78_RS11895
uniprot id: A0A3S6F2Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein B family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

935293:PL78 RS04725
gene id: 935293:PL78_RS04725
uniprot id: A0A3S6EXS7
names: Function
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.

935293:PL78 RS13825
gene id: 935293:PL78_RS13825
uniprot id: A0A3S6F2T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Cell inner membrane
messages: Involved in succinate export with YjjP. Both proteins are required for export.
messages: Membrane
messages: The transporter is composed of YjjB and YjjP.

935293:PL78 RS17635
gene id: 935293:PL78_RS17635
uniprot id: A0A3S6F4L6
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

935293:PL78 RS00850
gene id: 935293:PL78_RS00850
uniprot id: A0A3S6EVM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

935293:PL78 RS01370
gene id: 935293:PL78_RS01370
uniprot id: A0A3S6EVQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

935293:PL78 RS00400
gene id: 935293:PL78_RS00400
uniprot id: A0A3S6EUW6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

935293:PL78 RS02805
gene id: 935293:PL78_RS02805
uniprot id: A0A3S6EXD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

935293:PL78 RS02270
gene id: 935293:PL78_RS02270
uniprot id: A0A3S6EWH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

935293:PL78 RS01710
gene id: 935293:PL78_RS01710
uniprot id: A0A3S6EVW4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS06160
gene id: 935293:PL78_RS06160
uniprot id: A0A3S6EY58
names: Function
names: Similarity
messages: Belongs to the glutathione peroxidase family. BtuE subfamily.
messages: Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent.

935293:PL78 RS10150
gene id: 935293:PL78_RS10150
uniprot id: A0A3S6F0C9
names: Similarity
messages: Belongs to the phage portal family. PBSX subfamily.

935293:PL78 RS05825
gene id: 935293:PL78_RS05825
uniprot id: A0A3S6EY31
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

935293:PL78 RS12565
gene id: 935293:PL78_RS12565
uniprot id: A0A3S6F1R4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

935293:PL78 RS13470
gene id: 935293:PL78_RS13470
uniprot id: A0A3S6F277
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

935293:PL78 RS10940
gene id: 935293:PL78_RS10940
uniprot id: A0A3S6F0W7
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

935293:PL78 RS02255
gene id: 935293:PL78_RS02255
uniprot id: A0A3S6EX28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

935293:PL78 RS01960
gene id: 935293:PL78_RS01960
uniprot id: A0A3S6EW21
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS17805
gene id: 935293:PL78_RS17805
uniprot id: A0A3S6F517
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

935293:PL78 RS14565
gene id: 935293:PL78_RS14565
uniprot id: A0A3S6F2T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial secretin family. T3SS SctC subfamily.
messages: Cell outer membrane
messages: Component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells. Forms a ring-shaped multimeric structure with an apparent central pore in the outer membrane.
messages: Membrane
messages: The core secretion machinery of the T3SS is composed of approximately 20 different proteins, including cytoplasmic components, a base, an export apparatus and a needle. This subunit is part of the base, which anchors the injectisome in the bacterial cell envelope. Forms a stable homooligomeric complex.

935293:PL78 RS12390
gene id: 935293:PL78_RS12390
uniprot id: A0A3S6F1Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family. YidE subfamily.
messages: Cell membrane

935293:PL78 RS15415
gene id: 935293:PL78_RS15415
uniprot id: A0A3S6F398
names: Similarity
messages: Belongs to the phosphopentomutase family.

935293:PL78 RS11495
gene id: 935293:PL78_RS11495
uniprot id: A0A3S6F1I9
names: Similarity
messages: Belongs to the phosphoribulokinase family.

935293:PL78 RS08645
gene id: 935293:PL78_RS08645
uniprot id: A0A3S6EZJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

935293:PL78 RS10665
gene id: 935293:PL78_RS10665
uniprot id: A0A3S6F299
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rnk family.
messages: Interacts with the RNA polymerase.
messages: May act as an anti-Gre factor.

935293:PL78 RS10485
gene id: 935293:PL78_RS10485
uniprot id: A0A3S6F1L8
names: Similarity
messages: Belongs to the peptidase S1C family.

935293:PL78 RS11770
gene id: 935293:PL78_RS11770
uniprot id: A0A3S6F2C0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

935293:PL78 RS09300
gene id: 935293:PL78_RS09300
uniprot id: A0A3S6EZV5
names: Similarity
messages: Belongs to the phage portal family. PBSX subfamily.

935293:PL78 RS04515
gene id: 935293:PL78_RS04515
uniprot id: A0A3S6EXR4
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS07245
gene id: 935293:PL78_RS07245
uniprot id: A0A3S6EYQ9
names: Similarity
messages: Belongs to the leucine-binding protein family.

935293:PL78 RS12060
gene id: 935293:PL78_RS12060
uniprot id: A0A3S6F1J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

935293:PL78 RS04640
gene id: 935293:PL78_RS04640
uniprot id: A0A3S6EXE5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Multifunctional regulator of fatty acid metabolism.

935293:PL78 RS03195
gene id: 935293:PL78_RS03195
uniprot id: A0A3S6EWK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LpoB family.
messages: Cell outer membrane
messages: Interacts with PBP1b.
messages: Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b).

935293:PL78 RS15080
gene id: 935293:PL78_RS15080
uniprot id: A0A3S6F350
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

935293:PL78 RS15620
gene id: 935293:PL78_RS15620
uniprot id: A0A3S6F3T7
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

935293:PL78 RS00590
gene id: 935293:PL78_RS00590
uniprot id: A0A3S6EV09
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

935293:PL78 RS04005
gene id: 935293:PL78_RS04005
uniprot id: A0A3S6EX03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I38 family.
messages: Periplasm

935293:PL78 RS01540
gene id: 935293:PL78_RS01540
uniprot id: A0A3S6EX97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

935293:PL78 RS08530
gene id: 935293:PL78_RS08530
uniprot id: A0A3S6EZU1
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

935293:PL78 RS13485
gene id: 935293:PL78_RS13485
uniprot id: A0A3S6F2C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

935293:PL78 RS14140
gene id: 935293:PL78_RS14140
uniprot id: A0A3S6F2L9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 3 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

935293:PL78 RS05985
gene id: 935293:PL78_RS05985
uniprot id: A0A3S6EZ65
names: Similarity
messages: Belongs to the pyruvate kinase family.

935293:PL78 RS14220
gene id: 935293:PL78_RS14220
uniprot id: A0A3S6F2L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS04345
gene id: 935293:PL78_RS04345
uniprot id: A0A3S6EX84
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the PHP family.
messages: Binds 3 Zn(2+) ions per subunit.
messages: Homotrimer.

935293:PL78 RS03130
gene id: 935293:PL78_RS03130
uniprot id: A0A3S6EWH8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

935293:PL78 RS01365
gene id: 935293:PL78_RS01365
uniprot id: A0A3S6EVI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

935293:PL78 RS09260
gene id: 935293:PL78_RS09260
uniprot id: A0A3S6F1F8
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

935293:PL78 RS02430
gene id: 935293:PL78_RS02430
uniprot id: A0A3S6EWI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

935293:PL78 RS13435
gene id: 935293:PL78_RS13435
uniprot id: A0A3S6F2B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

935293:PL78 RS16930
gene id: 935293:PL78_RS16930
uniprot id: A0A3S6F467
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RcsD family.
messages: Cell inner membrane
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.
messages: Interacts with RcsC and RcsB.
messages: Phosphorylated by RcsC.

935293:PL78 RS08305
gene id: 935293:PL78_RS08305
uniprot id: A0A3S6EZQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

935293:PL78 RS06990
gene id: 935293:PL78_RS06990
uniprot id: A0A3S6EYM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

935293:PL78 RS06060
gene id: 935293:PL78_RS06060
uniprot id: A0A3S6EY40
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

935293:PL78 RS14010
gene id: 935293:PL78_RS14010
uniprot id: A0A3S6F2Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

935293:PL78 RS02265
gene id: 935293:PL78_RS02265
uniprot id: A0A3S6EW80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

935293:PL78 RS18700
gene id: 935293:PL78_RS18700
uniprot id: A0A3S6F6Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

935293:PL78 RS16450
gene id: 935293:PL78_RS16450
uniprot id: A0A3S6F420
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

935293:PL78 RS15300
gene id: 935293:PL78_RS15300
uniprot id: A0A3S6F3C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

935293:PL78 RS11175
gene id: 935293:PL78_RS11175
uniprot id: A0A3S6F114
names: Similarity
messages: Belongs to the Smg family.

935293:PL78 RS17820
gene id: 935293:PL78_RS17820
uniprot id: A0A3S6F4N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

935293:PL78 RS12625
gene id: 935293:PL78_RS12625
uniprot id: A0A3S6F2U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

935293:PL78 RS08000
gene id: 935293:PL78_RS08000
uniprot id: A0A3S6EZ52
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

935293:PL78 RS02290
gene id: 935293:PL78_RS02290
uniprot id: A0A3S6EW12
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Homodimer.

935293:PL78 RS08205
gene id: 935293:PL78_RS08205
uniprot id: A0A3S6EZN0
names: Function
names: Similarity
names: Subunit
messages: A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis.
messages: Belongs to the YihI family.
messages: Interacts with Der.

935293:PL78 RS01130
gene id: 935293:PL78_RS01130
uniprot id: A0A3S6EWH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

935293:PL78 RS13620
gene id: 935293:PL78_RS13620
uniprot id: A0A3S6F292
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

935293:PL78 RS12830
gene id: 935293:PL78_RS12830
uniprot id: A0A3S6F1U4
names: Cofactor
names: Function
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity.

935293:PL78 RS13280
gene id: 935293:PL78_RS13280
uniprot id: A0A3S6F284
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

935293:PL78 RS17605
gene id: 935293:PL78_RS17605
uniprot id: A0A3S6F4X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

935293:PL78 RS01295
gene id: 935293:PL78_RS01295
uniprot id: A0A3S6EVG4
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

935293:PL78 RS09960
gene id: 935293:PL78_RS09960
uniprot id: A0A3S6F1V9
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS17185
gene id: 935293:PL78_RS17185
uniprot id: A0A3S6F5X1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport.

935293:PL78 RS09935
gene id: 935293:PL78_RS09935
uniprot id: A0A3S6F0C3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

935293:PL78 RS01120
gene id: 935293:PL78_RS01120
uniprot id: A0A3S6EVC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

935293:PL78 RS09790
gene id: 935293:PL78_RS09790
uniprot id: A0A3S6F094
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

935293:PL78 RS15485
gene id: 935293:PL78_RS15485
uniprot id: A0A3S6F3E5
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

935293:PL78 RS12640
gene id: 935293:PL78_RS12640
uniprot id: A0A3S6F244
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

935293:PL78 RS11105
gene id: 935293:PL78_RS11105
uniprot id: A0A3S6F0W1
names: Cofactor
messages: Can also use Mn(2+) ion.

935293:PL78 RS07465
gene id: 935293:PL78_RS07465
uniprot id: A0A3S6EYX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-1 family.
messages: Cytoplasm

935293:PL78 RS10995
gene id: 935293:PL78_RS10995
uniprot id: A0A3S6F131
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

935293:PL78 RS11010
gene id: 935293:PL78_RS11010
uniprot id: A0A3S6F198
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

935293:PL78 RS09115
gene id: 935293:PL78_RS09115
uniprot id: A0A3S6EZU2
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

935293:PL78 RS15310
gene id: 935293:PL78_RS15310
uniprot id: A0A3S6F3I9
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

935293:PL78 RS15060
gene id: 935293:PL78_RS15060
uniprot id: A0A3S6F324
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS02695
gene id: 935293:PL78_RS02695
uniprot id: A0A3S6EWA1
names: Similarity
messages: Belongs to the UPF0434 family.

935293:PL78 RS05910
gene id: 935293:PL78_RS05910
uniprot id: A0A3S6EY37
names: Cofactor
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.

935293:PL78 RS17240
gene id: 935293:PL78_RS17240
uniprot id: A0A3S6F4C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

935293:PL78 RS12890
gene id: 935293:PL78_RS12890
uniprot id: A0A3S6F3G7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

935293:PL78 RS15720
gene id: 935293:PL78_RS15720
uniprot id: A0A3S6F3G3
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

935293:PL78 RS11795
gene id: 935293:PL78_RS11795
uniprot id: A0A3S6F1Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Cell membrane
messages: Membrane
messages: Rhomboid-type serine protease that catalyzes intramembrane proteolysis.

935293:PL78 RS18830
gene id: 935293:PL78_RS18830
uniprot id: A0A3S6F5D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GhoT/OrtT toxin family.
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS17160
gene id: 935293:PL78_RS17160
uniprot id: A0A3S6F4D6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Membrane

935293:PL78 RS06120
gene id: 935293:PL78_RS06120
uniprot id: A0A3S6EZQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 83 family.
messages: Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

935293:PL78 RS16760
gene id: 935293:PL78_RS16760
uniprot id: A0A3S6F425
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS15265
gene id: 935293:PL78_RS15265
uniprot id: A0A3S6F368
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E.
messages: Belongs to the RseA family.
messages: Cell inner membrane
messages: Interacts 1:1 with ECF RNA polymerase sigma-E (RpoE); this inhibits the interaction of sigma-E with the RNA polymerase catalytic core and leads to a decreased expression of sigma-E-regulated genes. Interacts with RseB.

935293:PL78 RS04240
gene id: 935293:PL78_RS04240
uniprot id: A0A3S6EX44
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

935293:PL78 RS02890
gene id: 935293:PL78_RS02890
uniprot id: A0A3S6EWD8
names: Similarity
messages: Belongs to the UPF0319 family.

935293:PL78 RS16710
gene id: 935293:PL78_RS16710
uniprot id: A0A3S6F415
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

935293:PL78 RS02635
gene id: 935293:PL78_RS02635
uniprot id: A0A3S6EXV7
names: Similarity
messages: Belongs to the asparaginase 1 family.

935293:PL78 RS08515
gene id: 935293:PL78_RS08515
uniprot id: A0A3S6EZQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

935293:PL78 RS11370
gene id: 935293:PL78_RS11370
uniprot id: A0A3S6F240
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

935293:PL78 RS08025
gene id: 935293:PL78_RS08025
uniprot id: A0A3S6EZ82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

935293:PL78 RS13925
gene id: 935293:PL78_RS13925
uniprot id: A0A3S6F2V0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

935293:PL78 RS14295
gene id: 935293:PL78_RS14295
uniprot id: A0A3S6F2R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

935293:PL78 RS04995
gene id: 935293:PL78_RS04995
uniprot id: A0A3S6EXJ8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

935293:PL78 RS06845
gene id: 935293:PL78_RS06845
uniprot id: A0A3S6EZ08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

935293:PL78 RS13905
gene id: 935293:PL78_RS13905
uniprot id: A0A3S6F2K4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane
messages: The complex is composed of two ATP-binding proteins (ThiQ), two transmembrane proteins (ThiP) and a solute-binding protein (ThiB).

935293:PL78 RS02305
gene id: 935293:PL78_RS02305
uniprot id: A0A3S6EX38
names: Similarity
messages: Belongs to the GST superfamily.

935293:PL78 RS18265
gene id: 935293:PL78_RS18265
uniprot id: A0A3S6F5A1
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS03110
gene id: 935293:PL78_RS03110
uniprot id: A0A3S6EXJ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

935293:PL78 RS12470
gene id: 935293:PL78_RS12470
uniprot id: A0A3S6F1R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

935293:PL78 RS02610
gene id: 935293:PL78_RS02610
uniprot id: A0A3S6EW86
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

935293:PL78 RS07780
gene id: 935293:PL78_RS07780
uniprot id: A0A3S6F042
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

935293:PL78 RS16910
gene id: 935293:PL78_RS16910
uniprot id: A0A3S6F454
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

935293:PL78 RS15245
gene id: 935293:PL78_RS15245
uniprot id: A0A3S6F478
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. SrmB subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity.
messages: Interacts with the 50S ribosomal subunit.

935293:PL78 RS13145
gene id: 935293:PL78_RS13145
uniprot id: A0A3S6F2F4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Homodimer.
messages: May be involved in cell division.

935293:PL78 RS11820
gene id: 935293:PL78_RS11820
uniprot id: A0A3S6F2C9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

935293:PL78 RS03770
gene id: 935293:PL78_RS03770
uniprot id: B6A878
names: Disruption Phenotype
names: Function
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Cells with a disrupted yenA1-yenA2-chi2-yenB-yenC1-yenC2 locus are no longer pathogenic in C.zealandica larvae.
messages: Part of an orally active toxin complex (TC) with strong insecticidal effects on larvae of the Coleoptera Costelytra zealandica, Acrossidius tasmania and Adoryphorus couloni and some Lepidoptera larvae (PubMed:21278295, PubMed:22158901). The TC has an endochitinase activity (PubMed:21278295) (Probable).
messages: Secreted
messages: Semipurified toxin complex consists of at least YenA1-YenA2-YenB-YenC1-YenC2-Chi1-Chi2 (PubMed:21278295). The Yen-TC:K9 subcomplex is about 26 nm tall and 22 nm in diameter with 5-fold symmetry and 5 copies of YenA1, YenA2, Chi1 and Chi2; the chitinase subunits may be solvent accessible on the exterior the complex (PubMed:22158901). The Yen-TC:K9 subcomplex has no insecticidal activity (PubMed:22158901). The native complex with additional YenB, YenC1 and YenC2 subunits is 16 nm taller and is insecticidal; the toxicity-conferring subunits are present at about 1 copy each (PubMed:22158901).
messages: The isolated toxin complex includes 3 peptides starting between residues 768 and 778 of this protein, which might be physiologically relevant.

935293:PL78 RS17260
gene id: 935293:PL78_RS17260
uniprot id: A0A3S6F4I4
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS15490
gene id: 935293:PL78_RS15490
uniprot id: A0A3S6F3E8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 2 iron ions per dimer. The dimer may bind additional iron ions.
messages: Homodimer; may form tetramers and higher multimers.
messages: Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.

935293:PL78 RS07235
gene id: 935293:PL78_RS07235
uniprot id: A0A3S6EZ01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

935293:PL78 RS02245
gene id: 935293:PL78_RS02245
uniprot id: A0A3S6EW08
names: Similarity
messages: Belongs to the UDPGP type 2 family.

935293:PL78 RS06925
gene id: 935293:PL78_RS06925
uniprot id: A0A3S6EYN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

935293:PL78 RS04265
gene id: 935293:PL78_RS04265
uniprot id: A0A3S6EX52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

935293:PL78 RS06695
gene id: 935293:PL78_RS06695
uniprot id: A0A3S6EYJ5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

935293:PL78 RS11840
gene id: 935293:PL78_RS11840
uniprot id: A0A3S6F1A0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS04400
gene id: 935293:PL78_RS04400
uniprot id: A0A3S6EX73
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

935293:PL78 RS07020
gene id: 935293:PL78_RS07020
uniprot id: A0A3S6EYP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

935293:PL78 RS13130
gene id: 935293:PL78_RS13130
uniprot id: A0A3S6F285
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

935293:PL78 RS04615
gene id: 935293:PL78_RS04615
uniprot id: A0A3S6EXT5
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

935293:PL78 RS01625
gene id: 935293:PL78_RS01625
uniprot id: A0A3S6EW24
names: Similarity
messages: Belongs to the aldose epimerase family.

935293:PL78 RS09640
gene id: 935293:PL78_RS09640
uniprot id: A0A3S6F063
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

935293:PL78 RS14865
gene id: 935293:PL78_RS14865
uniprot id: A0A3S6F3D1
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.

935293:PL78 RS06175
gene id: 935293:PL78_RS06175
uniprot id: A0A3S6EY74
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

935293:PL78 RS13025
gene id: 935293:PL78_RS13025
uniprot id: A0A3S6F2B4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

935293:PL78 RS17750
gene id: 935293:PL78_RS17750
uniprot id: A0A3S6F4L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

935293:PL78 RS07430
gene id: 935293:PL78_RS07430
uniprot id: A0A3S6EYY9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

935293:PL78 RS08690
gene id: 935293:PL78_RS08690
uniprot id: A0A3S6EZH7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

935293:PL78 RS08425
gene id: 935293:PL78_RS08425
uniprot id: A0A3S6EZG1
names: Similarity
messages: Belongs to the peptidase M16 family.

935293:PL78 RS06680
gene id: 935293:PL78_RS06680
uniprot id: A0A3S6F019
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

935293:PL78 RS05100
gene id: 935293:PL78_RS05100
uniprot id: A0A3S6EXN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

935293:PL78 RS11805
gene id: 935293:PL78_RS11805
uniprot id: A0A3S6F189
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

935293:PL78 RS01305
gene id: 935293:PL78_RS01305
uniprot id: A0A3S6EVH3
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

935293:PL78 RS00830
gene id: 935293:PL78_RS00830
uniprot id: A0A3S6EV79
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

935293:PL78 RS05225
gene id: 935293:PL78_RS05225
uniprot id: A0A3S6EXW5
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

935293:PL78 RS14280
gene id: 935293:PL78_RS14280
uniprot id: A0A3S6F487
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

935293:PL78 RS05755
gene id: 935293:PL78_RS05755
uniprot id: A0A3S6EXZ8
names: Function
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
messages: Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism and in the biotin biosynthesis.

935293:PL78 RS15665
gene id: 935293:PL78_RS15665
uniprot id: A0A3S6F3Q6
names: Similarity
messages: Belongs to the UPF0339 family. Duplicated subfamily.

935293:PL78 RS00320
gene id: 935293:PL78_RS00320
uniprot id: A0A3S6EUV7
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

935293:PL78 RS09885
gene id: 935293:PL78_RS09885
uniprot id: A0A3S6F199
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

935293:PL78 RS01265
gene id: 935293:PL78_RS01265
uniprot id: A0A3S6EVG1
names: Cofactor
messages: Divalent metal ions. Mg(2+) is the most effective.

935293:PL78 RS17190
gene id: 935293:PL78_RS17190
uniprot id: A0A3S6F481
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

935293:PL78 RS08915
gene id: 935293:PL78_RS08915
uniprot id: A0A3S6EZQ7
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS11265
gene id: 935293:PL78_RS11265
uniprot id: A0A3S6F133
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

935293:PL78 RS05740
gene id: 935293:PL78_RS05740
uniprot id: A0A3S6EXY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS13560
gene id: 935293:PL78_RS13560
uniprot id: A0A3S6F2K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

935293:PL78 RS19265
gene id: 935293:PL78_RS19265
uniprot id: A0A3S6EYN0
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

935293:PL78 RS02420
gene id: 935293:PL78_RS02420
uniprot id: A0A3S6EWK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

935293:PL78 RS10545
gene id: 935293:PL78_RS10545
uniprot id: A0A3S6F0V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

935293:PL78 RS14980
gene id: 935293:PL78_RS14980
uniprot id: A0A3S6F328
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS18420
gene id: 935293:PL78_RS18420
uniprot id: A0A3S6F511
names: Similarity
messages: Belongs to the heat shock protein 70 family.

935293:PL78 RS01830
gene id: 935293:PL78_RS01830
uniprot id: A0A3S6EXE2
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS05485
gene id: 935293:PL78_RS05485
uniprot id: A0A3S6EYA0
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

935293:PL78 RS15575
gene id: 935293:PL78_RS15575
uniprot id: A0A3S6F4Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

935293:PL78 RS14255
gene id: 935293:PL78_RS14255
uniprot id: A0A3S6F2S4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

935293:PL78 RS08230
gene id: 935293:PL78_RS08230
uniprot id: A0A3S6F0D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

935293:PL78 RS03075
gene id: 935293:PL78_RS03075
uniprot id: A0A3S6EWY3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MSOX/MTOX family. MTOX subfamily.
messages: Binds 1 FAD per subunit.
messages: Catalyzes the oxidative demethylation of N-methyl-L-tryptophan.
messages: Monomer.

935293:PL78 RS16070
gene id: 935293:PL78_RS16070
uniprot id: A0A3S6F3N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

935293:PL78 RS01660
gene id: 935293:PL78_RS01660
uniprot id: A0A3S6EVV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.
messages: Belongs to the AcrZ family.
messages: Cell membrane
messages: Part of the AcrA-AcrB-AcrZ-TolC efflux pump, interacts directly with AcrB.

935293:PL78 RS04720
gene id: 935293:PL78_RS04720
uniprot id: A0A3S6EXE6
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

935293:PL78 RS06775
gene id: 935293:PL78_RS06775
uniprot id: A0A3S6EYH7
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS08140
gene id: 935293:PL78_RS08140
uniprot id: A0A3S6EZI1
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

935293:PL78 RS14095
gene id: 935293:PL78_RS14095
uniprot id: A0A3S6F2N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

935293:PL78 RS03935
gene id: 935293:PL78_RS03935
uniprot id: A0A3S6EY20
names: Similarity
messages: Belongs to the group II decarboxylase family.

935293:PL78 RS12220
gene id: 935293:PL78_RS12220
uniprot id: A0A3S6F1M6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers. Binds only one seryl-tRNA(Sec) per dimer.

935293:PL78 RS09170
gene id: 935293:PL78_RS09170
uniprot id: A0A3S6EZV1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

935293:PL78 RS08720
gene id: 935293:PL78_RS08720
uniprot id: A0A3S6EZZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

935293:PL78 RS14035
gene id: 935293:PL78_RS14035
uniprot id: A0A3S6F2G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

935293:PL78 RS00505
gene id: 935293:PL78_RS00505
uniprot id: A0A3S6EUY8
names: Function
names: Similarity
messages: A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S. The H(2)S produced by this enzyme may modulate central metabolism.
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family. Cds1 subfamily.

935293:PL78 RS10290
gene id: 935293:PL78_RS10290
uniprot id: A0A3S6F0Q5
names: Similarity
messages: Belongs to the UxaA family.

935293:PL78 RS17320
gene id: 935293:PL78_RS17320
uniprot id: A0A3S6F4N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

935293:PL78 RS14465
gene id: 935293:PL78_RS14465
uniprot id: A0A3S6F2R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

935293:PL78 RS08845
gene id: 935293:PL78_RS08845
uniprot id: A0A3S6F004
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

935293:PL78 RS05945
gene id: 935293:PL78_RS05945
uniprot id: A0A3S6EYF3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS16680
gene id: 935293:PL78_RS16680
uniprot id: A0A3S6F416
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS09165
gene id: 935293:PL78_RS09165
uniprot id: A0A3S6EZS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
messages: Cell membrane
messages: Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine.
messages: Membrane

935293:PL78 RS03010
gene id: 935293:PL78_RS03010
uniprot id: A0A3S6EXI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

935293:PL78 RS08465
gene id: 935293:PL78_RS08465
uniprot id: A0A3S6F102
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP subfamily.
messages: Catalyzes the proton-dependent transport of glutamate and aspartate.
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS13315
gene id: 935293:PL78_RS13315
uniprot id: A0A3S6F246
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS12970
gene id: 935293:PL78_RS12970
uniprot id: A0A3S6F258
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

935293:PL78 RS00360
gene id: 935293:PL78_RS00360
uniprot id: A0A3S6EUV8
names: Subcellular Location Annotation
messages: Cell inner membrane

935293:PL78 RS15905
gene id: 935293:PL78_RS15905
uniprot id: A0A3S6F3P9
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.
messages: Membrane

935293:PL78 RS06510
gene id: 935293:PL78_RS06510
uniprot id: A0A3S6EYL3
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

935293:PL78 RS08100
gene id: 935293:PL78_RS08100
uniprot id: A0A3S6EZ70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

935293:PL78 RS00645
gene id: 935293:PL78_RS00645
uniprot id: A0A3S6EV19
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

935293:PL78 RS08220
gene id: 935293:PL78_RS08220
uniprot id: A0A3S6EZB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

935293:PL78 RS00660
gene id: 935293:PL78_RS00660
uniprot id: A0A3S6EV27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

935293:PL78 RS17075
gene id: 935293:PL78_RS17075
uniprot id: A0A3S6F483
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

935293:PL78 RS06460
gene id: 935293:PL78_RS06460
uniprot id: A0A3S6EYK1
names: Function
names: Similarity
messages: Belongs to the AcpH family.
messages: Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP.

935293:PL78 RS16615
gene id: 935293:PL78_RS16615
uniprot id: A0A3S6F4C9
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS18065
gene id: 935293:PL78_RS18065
uniprot id: A0A3S6F564
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

935293:PL78 RS04285
gene id: 935293:PL78_RS04285
uniprot id: A0A3S6EX76
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

935293:PL78 RS16690
gene id: 935293:PL78_RS16690
uniprot id: A0A3S6F509
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

935293:PL78 RS07015
gene id: 935293:PL78_RS07015
uniprot id: A0A3S6EYN7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell membrane

935293:PL78 RS13085
gene id: 935293:PL78_RS13085
uniprot id: A0A3S6F2E9
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

935293:PL78 RS08960
gene id: 935293:PL78_RS08960
uniprot id: A0A3S6EZR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Part of the pseudopilus tip complex that is critical for the recognition and binding of secretion substrates.
messages: Membrane

935293:PL78 RS07880
gene id: 935293:PL78_RS07880
uniprot id: A0A3S6F062
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activity of this regulatory enzyme is affected by several metabolites. Allosterically and non-competitively inhibited by fructose 1,6-bisphosphate (FBP) and unphosphorylated phosphocarrier protein EIIA-Glc (III-Glc), an integral component of the bacterial phosphotransferase (PTS) system.
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium). Heterodimer with EIIA-Glc. Binds 1 zinc ion per glycerol kinase EIIA-Glc dimer. The zinc ion is important for dimerization.
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

935293:PL78 RS15560
gene id: 935293:PL78_RS15560
uniprot id: A0A3S6F3N8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

935293:PL78 RS06490
gene id: 935293:PL78_RS06490
uniprot id: A0A3S6EYF0
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS04300
gene id: 935293:PL78_RS04300
uniprot id: A0A3S6EX65
names: Similarity
messages: Belongs to the UPF0162 family.

935293:PL78 RS18495
gene id: 935293:PL78_RS18495
uniprot id: A0A3S6F5C1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

935293:PL78 RS18060
gene id: 935293:PL78_RS18060
uniprot id: A0A3S6F4S0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

935293:PL78 RS15760
gene id: 935293:PL78_RS15760
uniprot id: A0A3S6F3P4
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

935293:PL78 RS14435
gene id: 935293:PL78_RS14435
uniprot id: A0A3S6F2S8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

935293:PL78 RS16385
gene id: 935293:PL78_RS16385
uniprot id: A0A3S6F3W6
names: Similarity
messages: Belongs to the MlaA family.

935293:PL78 RS05050
gene id: 935293:PL78_RS05050
uniprot id: A0A3S6EXM5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapA family.
messages: Cell inner membrane
messages: Involved in the assembly of lipopolysaccharide (LPS).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS04385
gene id: 935293:PL78_RS04385
uniprot id: A0A3S6EYU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

935293:PL78 RS06780
gene id: 935293:PL78_RS06780
uniprot id: A0A3S6EYV7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS10380
gene id: 935293:PL78_RS10380
uniprot id: A0A3S6F0K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

935293:PL78 RS06785
gene id: 935293:PL78_RS06785
uniprot id: A0A3S6F038
names: Subunit
messages: Monomer.

935293:PL78 RS02445
gene id: 935293:PL78_RS02445
uniprot id: A0A3S6EW50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

935293:PL78 RS12510
gene id: 935293:PL78_RS12510
uniprot id: A0A3S6F1N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

935293:PL78 RS03090
gene id: 935293:PL78_RS03090
uniprot id: A0A3S6EY44
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

935293:PL78 RS04835
gene id: 935293:PL78_RS04835
uniprot id: A0A3S6EXU6
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

935293:PL78 RS06540
gene id: 935293:PL78_RS06540
uniprot id: A0A3S6EYG0
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

935293:PL78 RS18180
gene id: 935293:PL78_RS18180
uniprot id: A0A3S6F4V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS14190
gene id: 935293:PL78_RS14190
uniprot id: A0A3S6F2N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

935293:PL78 RS17950
gene id: 935293:PL78_RS17950
uniprot id: A0A3S6F547
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

935293:PL78 RS05420
gene id: 935293:PL78_RS05420
uniprot id: A0A3S6EYV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA gyrase inhibitor family.
messages: Cytoplasm
messages: Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell.
messages: Interacts with DNA gyrase.

935293:PL78 RS06005
gene id: 935293:PL78_RS06005
uniprot id: A0A3S6EY29
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

935293:PL78 RS12570
gene id: 935293:PL78_RS12570
uniprot id: A0A3S6F1T7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

935293:PL78 RS09855
gene id: 935293:PL78_RS09855
uniprot id: A0A3S6F069
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsP family.
messages: Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress.
messages: Periplasm

935293:PL78 RS10110
gene id: 935293:PL78_RS10110
uniprot id: A0A3S6F1Z1
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

935293:PL78 RS11270
gene id: 935293:PL78_RS11270
uniprot id: A0A3S6F220
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

935293:PL78 RS16650
gene id: 935293:PL78_RS16650
uniprot id: A0A3S6F458
names: Similarity
messages: Belongs to the UPF0304 family.

935293:PL78 RS16555
gene id: 935293:PL78_RS16555
uniprot id: A0A3S6F482
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS05410
gene id: 935293:PL78_RS05410
uniprot id: A0A3S6EXU3
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

935293:PL78 RS11985
gene id: 935293:PL78_RS11985
uniprot id: A0A3S6F1D2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

935293:PL78 RS12005
gene id: 935293:PL78_RS12005
uniprot id: A0A3S6F1F3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AcsB/BcsB family.
messages: Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP).
messages: Cell inner membrane
messages: Tightly associated with the cellulose synthase catalytic subunit.

935293:PL78 RS07105
gene id: 935293:PL78_RS07105
uniprot id: A0A3S6F086
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

935293:PL78 RS05150
gene id: 935293:PL78_RS05150
uniprot id: A0A3S6EXP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

935293:PL78 RS17460
gene id: 935293:PL78_RS17460
uniprot id: A0A3S6F630
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

935293:PL78 RS14040
gene id: 935293:PL78_RS14040
uniprot id: A0A3S6F2J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

935293:PL78 RS01135
gene id: 935293:PL78_RS01135
uniprot id: A0A3S6EVE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

935293:PL78 RS07290
gene id: 935293:PL78_RS07290
uniprot id: A0A3S6EZ87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

935293:PL78 RS07055
gene id: 935293:PL78_RS07055
uniprot id: A0A3S6F076
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Has an organic peroxide-dependent peroxidase activity.

935293:PL78 RS07925
gene id: 935293:PL78_RS07925
uniprot id: A0A3S6EZ63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily.
messages: Cell inner membrane
messages: Divalent metal cation transporter which exports Zn(2+), Cd(2+) and possibly Fe(2+). May be involved in zinc and iron detoxification by efflux.
messages: Homodimer.
messages: Membrane

935293:PL78 RS17180
gene id: 935293:PL78_RS17180
uniprot id: A0A3S6F4P1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

935293:PL78 RS11940
gene id: 935293:PL78_RS11940
uniprot id: A0A3S6F1T2
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS09410
gene id: 935293:PL78_RS09410
uniprot id: A0A3S6F1I8
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

935293:PL78 RS02215
gene id: 935293:PL78_RS02215
uniprot id: A0A3S6EW69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

935293:PL78 RS14025
gene id: 935293:PL78_RS14025
uniprot id: A0A3S6F2X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

935293:PL78 RS07085
gene id: 935293:PL78_RS07085
uniprot id: A0A3S6EYX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

935293:PL78 RS13075
gene id: 935293:PL78_RS13075
uniprot id: A0A3S6F2C3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

935293:PL78 RS14000
gene id: 935293:PL78_RS14000
uniprot id: A0A3S6F3K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

935293:PL78 RS15145
gene id: 935293:PL78_RS15145
uniprot id: A0A3S6F393
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

935293:PL78 RS12610
gene id: 935293:PL78_RS12610
uniprot id: A0A3S6F1Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

935293:PL78 RS18475
gene id: 935293:PL78_RS18475
uniprot id: A0A3S6F529
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS19215
gene id: 935293:PL78_RS19215
uniprot id: A0A3S6F5H3
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.

935293:PL78 RS16080
gene id: 935293:PL78_RS16080
uniprot id: A0A3S6F588
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS11345
gene id: 935293:PL78_RS11345
uniprot id: A0A3S6F1G1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

935293:PL78 RS00425
gene id: 935293:PL78_RS00425
uniprot id: A0A3S6EV64
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

935293:PL78 RS13120
gene id: 935293:PL78_RS13120
uniprot id: A0A3S6F333
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

935293:PL78 RS16920
gene id: 935293:PL78_RS16920
uniprot id: A0A3S6F5R1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Autophosphorylated. Activation probably requires a transfer of a phosphate group from a His in the transmitter domain to an Asp in the receiver domain.
messages: Belongs to the RcsC family.
messages: Cell inner membrane
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane-associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.
messages: Interacts with RcsD.

935293:PL78 RS13895
gene id: 935293:PL78_RS13895
uniprot id: A0A3S6F2I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS17055
gene id: 935293:PL78_RS17055
uniprot id: A0A3S6F596
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

935293:PL78 RS00960
gene id: 935293:PL78_RS00960
uniprot id: A0A3S6EWY6
names: Similarity
messages: Belongs to the ClpA/ClpB family.

935293:PL78 RS06050
gene id: 935293:PL78_RS06050
uniprot id: A0A3S6EYB8
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

935293:PL78 RS10725
gene id: 935293:PL78_RS10725
uniprot id: A0A3S6F0R9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

935293:PL78 RS14750
gene id: 935293:PL78_RS14750
uniprot id: A0A3S6F2W6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

935293:PL78 RS12205
gene id: 935293:PL78_RS12205
uniprot id: A0A3S6F343
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyltransferase 3 family.
messages: Cell inner membrane
messages: Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units.

935293:PL78 RS02960
gene id: 935293:PL78_RS02960
uniprot id: A0A3S6EXH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
messages: Cell membrane
messages: K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.

935293:PL78 RS18330
gene id: 935293:PL78_RS18330
uniprot id: A0A3S6F4Y7
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

935293:PL78 RS05125
gene id: 935293:PL78_RS05125
uniprot id: A0A3S6EY35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

935293:PL78 RS04655
gene id: 935293:PL78_RS04655
uniprot id: A0A3S6EXD3
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

935293:PL78 RS10715
gene id: 935293:PL78_RS10715
uniprot id: A0A3S6F2A8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS08240
gene id: 935293:PL78_RS08240
uniprot id: A0A3S6EZK6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

935293:PL78 RS02935
gene id: 935293:PL78_RS02935
uniprot id: A0A3S6EY14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Interacts with the TusBCD complex. Interacts with MnmA.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Could accept sulfur from TusD.

935293:PL78 RS07630
gene id: 935293:PL78_RS07630
uniprot id: A0A3S6EYY6
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

935293:PL78 RS00585
gene id: 935293:PL78_RS00585
uniprot id: A0A3S6EVJ3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

935293:PL78 RS03845
gene id: 935293:PL78_RS03845
uniprot id: A0A3S6EXE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

935293:PL78 RS09995
gene id: 935293:PL78_RS09995
uniprot id: A0A3S6F0P2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

935293:PL78 RS02855
gene id: 935293:PL78_RS02855
uniprot id: A0A3S6EXE9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer and homodimer.
messages: The extracellular loops are most variable in sequence, and in some bacteria confer sensitivity to phage and/or colicins.
messages: With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage.

935293:PL78 RS09800
gene id: 935293:PL78_RS09800
uniprot id: A0A3S6F0K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

935293:PL78 RS08445
gene id: 935293:PL78_RS08445
uniprot id: A0A3S6EZP6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

935293:PL78 RS07040
gene id: 935293:PL78_RS07040
uniprot id: A0A3S6EZ38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

935293:PL78 RS15715
gene id: 935293:PL78_RS15715
uniprot id: A0A3S6F3R8
names: Similarity
messages: Belongs to the GppA/Ppx family.

935293:PL78 RS11925
gene id: 935293:PL78_RS11925
uniprot id: A0A3S6F1K7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

935293:PL78 RS07795
gene id: 935293:PL78_RS07795
uniprot id: A0A3S6EZH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

935293:PL78 RS07295
gene id: 935293:PL78_RS07295
uniprot id: A0A3S6EYS0
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

935293:PL78 RS15220
gene id: 935293:PL78_RS15220
uniprot id: A0A3S6F3K1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

935293:PL78 RS08570
gene id: 935293:PL78_RS08570
uniprot id: A0A3S6EZX0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

935293:PL78 RS14965
gene id: 935293:PL78_RS14965
uniprot id: A0A3S6F3F2
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

935293:PL78 RS15285
gene id: 935293:PL78_RS15285
uniprot id: A0A3S6F3A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

935293:PL78 RS10580
gene id: 935293:PL78_RS10580
uniprot id: A0A3S6F0P5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

935293:PL78 RS17740
gene id: 935293:PL78_RS17740
uniprot id: A0A3S6F4S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Flagellar protein that affects chemotactic events.
messages: Membrane

935293:PL78 RS09380
gene id: 935293:PL78_RS09380
uniprot id: A0A3S6F0Z9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

935293:PL78 RS02535
gene id: 935293:PL78_RS02535
uniprot id: A0A3S6EXT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

935293:PL78 RS01430
gene id: 935293:PL78_RS01430
uniprot id: A0A3S6EVI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

935293:PL78 RS08480
gene id: 935293:PL78_RS08480
uniprot id: A0A3S6EZH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell inner membrane
messages: Membrane
messages: Transports acetate.

935293:PL78 RS18185
gene id: 935293:PL78_RS18185
uniprot id: A0A3S6F4X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Membrane

935293:PL78 RS08600
gene id: 935293:PL78_RS08600
uniprot id: A0A3S6EZJ7
names: Subcellular Location Annotation
messages: Cytoplasm

935293:PL78 RS08275
gene id: 935293:PL78_RS08275
uniprot id: A0A3S6EZD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FrdC family.
messages: Cell membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.

935293:PL78 RS04270
gene id: 935293:PL78_RS04270
uniprot id: A0A3S6EXI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
messages: Homodimer.

935293:PL78 RS02595
gene id: 935293:PL78_RS02595
uniprot id: A0A3S6EW81
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

935293:PL78 RS00375
gene id: 935293:PL78_RS00375
uniprot id: A0A3S6EV52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

935293:PL78 RS08345
gene id: 935293:PL78_RS08345
uniprot id: A0A3S6EZS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

935293:PL78 RS13490
gene id: 935293:PL78_RS13490
uniprot id: A0A3S6F2F8
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS08715
gene id: 935293:PL78_RS08715
uniprot id: A0A3S6EZU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Syd family.
messages: Cell inner membrane
messages: Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.

935293:PL78 RS11900
gene id: 935293:PL78_RS11900
uniprot id: A0A3S6F1B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

935293:PL78 RS04730
gene id: 935293:PL78_RS04730
uniprot id: A0A3S6EZ15
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

935293:PL78 RS04095
gene id: 935293:PL78_RS04095
uniprot id: A0A3S6EX26
names: Similarity
messages: Belongs to the PhoH family.

935293:PL78 RS15825
gene id: 935293:PL78_RS15825
uniprot id: A0A3S6F3X3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

935293:PL78 RS06055
gene id: 935293:PL78_RS06055
uniprot id: A0A3S6EYK8
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

935293:PL78 RS09065
gene id: 935293:PL78_RS09065
uniprot id: A0A3S6EZT0
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

935293:PL78 RS09825
gene id: 935293:PL78_RS09825
uniprot id: A0A3S6F084
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS18900
gene id: 935293:PL78_RS18900
uniprot id: A0A3S6F758
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ProQ family.
messages: Cytoplasm
messages: RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism.

935293:PL78 RS06115
gene id: 935293:PL78_RS06115
uniprot id: A0A3S6EYI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArnE family.
messages: Cell inner membrane
messages: Heterodimer of ArnE and ArnF.
messages: Membrane
messages: Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.

935293:PL78 RS13820
gene id: 935293:PL78_RS13820
uniprot id: A0A3S6F2D3
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

935293:PL78 RS08125
gene id: 935293:PL78_RS08125
uniprot id: A0A3S6EZA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

935293:PL78 RS16575
gene id: 935293:PL78_RS16575
uniprot id: A0A3S6F3V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

935293:PL78 RS13000
gene id: 935293:PL78_RS13000
uniprot id: A0A3S6F1Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

935293:PL78 RS03985
gene id: 935293:PL78_RS03985
uniprot id: A0A3S6EY30
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10B family.
messages: Binds 1 zinc ion per subunit.

935293:PL78 RS17840
gene id: 935293:PL78_RS17840
uniprot id: A0A3S6F4U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

935293:PL78 RS15445
gene id: 935293:PL78_RS15445
uniprot id: A0A3S6F4B8
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS15585
gene id: 935293:PL78_RS15585
uniprot id: A0A3S6F3G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS02020
gene id: 935293:PL78_RS02020
uniprot id: A0A3S6EWC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. Tam family.
messages: Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
messages: Cytoplasm

935293:PL78 RS11970
gene id: 935293:PL78_RS11970
uniprot id: A0A3S6F1H7
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

935293:PL78 RS00705
gene id: 935293:PL78_RS00705
uniprot id: A0A3S6EWT4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

935293:PL78 RS14795
gene id: 935293:PL78_RS14795
uniprot id: A0A3S6F4I8
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

935293:PL78 RS15765
gene id: 935293:PL78_RS15765
uniprot id: A0A3S6F3S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

935293:PL78 RS02400
gene id: 935293:PL78_RS02400
uniprot id: A0A3S6EW47
names: Similarity
names: Subunit
messages: Belongs to the glutaredoxin family.
messages: Monomer.

935293:PL78 RS10680
gene id: 935293:PL78_RS10680
uniprot id: A0A3S6F0R4
names: Similarity
messages: Belongs to the UPF0307 family.

935293:PL78 RS15390
gene id: 935293:PL78_RS15390
uniprot id: A0A3S6F3D0
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS17265
gene id: 935293:PL78_RS17265
uniprot id: A0A3S6F4M7
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

935293:PL78 RS12840
gene id: 935293:PL78_RS12840
uniprot id: A0A3S6F3F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

935293:PL78 RS09840
gene id: 935293:PL78_RS09840
uniprot id: A0A3S6F0A3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

935293:PL78 RS10675
gene id: 935293:PL78_RS10675
uniprot id: A0A3S6F0Q8
names: Similarity
messages: Belongs to the peptidase U62 family.

935293:PL78 RS05515
gene id: 935293:PL78_RS05515
uniprot id: A0A3S6EXV0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

935293:PL78 RS03785
gene id: 935293:PL78_RS03785
uniprot id: B6A881
names: Activity Regulation
names: Disruption Phenotype
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double yenC1-yenC2 deletion is no longer pathogenic in C.zealandica larvae.
messages: Belongs to the RHS family.
messages: Part of an orally active toxin complex (TC) with strong insecticidal effects on larvae of the Coleoptera Costelytra zealandica, Acrossidius tasmania and Adoryphorus couloni and some Lepidoptera larvae (PubMed:21278295). The TC has an endochitinase activity (PubMed:21278295) (Probable).
messages: Secreted
messages: Semipurified toxin complex consists of at least YenA1-YenA2-YenB-YenC1-YenC2-Chi1-Chi2 (PubMed:21278295). The Yen-TC:K9 subcomplex is about 26 nm tall and 22 nm in diameter with 5-fold symmetry and 5 copies of YenA1, YenA2, Chi1 and Chi2; the chitinase subunits may be solvent accessible on the exterior the complex (PubMed:22158901). The Yen-TC:K9 subcomplex has no insecticidal activity (PubMed:22158901). The native complex with additional YenB, YenC1 and YenC2 subunits is 16 nm taller and is insecticidal; the toxicity-conferring subunits are present at about 1 copy each (PubMed:22158901).
messages: Toxin complex is secreted when grown at 25 degrees Celsius or less; at higher temperatures the proteins are present intracellularly but not secreted.

935293:PL78 RS15250
gene id: 935293:PL78_RS15250
uniprot id: A0A3S6F3B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

935293:PL78 RS10705
gene id: 935293:PL78_RS10705
uniprot id: A0A3S6F0N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell membrane
messages: Forms an efflux pump with AaeB.

935293:PL78 RS07730
gene id: 935293:PL78_RS07730
uniprot id: A0A3S6F033
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS11815
gene id: 935293:PL78_RS11815
uniprot id: A0A3S6F1E1
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

935293:PL78 RS17880
gene id: 935293:PL78_RS17880
uniprot id: A0A3S6F5S5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

935293:PL78 RS08185
gene id: 935293:PL78_RS08185
uniprot id: A0A3S6EZC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

935293:PL78 RS09595
gene id: 935293:PL78_RS09595
uniprot id: A0A3S6F0B5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS00445
gene id: 935293:PL78_RS00445
uniprot id: A0A3S6EWN4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

935293:PL78 RS08120
gene id: 935293:PL78_RS08120
uniprot id: A0A3S6EZ95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

935293:PL78 RS01335
gene id: 935293:PL78_RS01335
uniprot id: A0A3S6EVX4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SeqA family.
messages: Cytoplasm
messages: Homodimer. Polymerizes to form helical filaments.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.

935293:PL78 RS06465
gene id: 935293:PL78_RS06465
uniprot id: A0A3S6EYU2
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

935293:PL78 RS17170
gene id: 935293:PL78_RS17170
uniprot id: A0A3S6F4K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Periplasm

935293:PL78 RS04805
gene id: 935293:PL78_RS04805
uniprot id: A0A3S6EXF8
names: Similarity
messages: Belongs to the UPF0225 family.

935293:PL78 RS12670
gene id: 935293:PL78_RS12670
uniprot id: A0A3S6F1W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

935293:PL78 RS07360
gene id: 935293:PL78_RS07360
uniprot id: A0A3S6EYU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

935293:PL78 RS14045
gene id: 935293:PL78_RS14045
uniprot id: A0A3S6F2M1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

935293:PL78 RS06670
gene id: 935293:PL78_RS06670
uniprot id: A0A3S6EYF8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

935293:PL78 RS14655
gene id: 935293:PL78_RS14655
uniprot id: A0A3S6F341
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

935293:PL78 RS04010
gene id: 935293:PL78_RS04010
uniprot id: A0A3S6EXD2
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS16875
gene id: 935293:PL78_RS16875
uniprot id: A0A3S6F423
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

935293:PL78 RS01340
gene id: 935293:PL78_RS01340
uniprot id: A0A3S6EX56
names: Similarity
messages: Belongs to the phosphohexose mutase family.

935293:PL78 RS17315
gene id: 935293:PL78_RS17315
uniprot id: A0A3S6F4J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

935293:PL78 RS07060
gene id: 935293:PL78_RS07060
uniprot id: A0A3S6EYN2
names: Similarity
messages: Belongs to the peptidase S51 family.

935293:PL78 RS16135
gene id: 935293:PL78_RS16135
uniprot id: A0A3S6F4P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

935293:PL78 RS12660
gene id: 935293:PL78_RS12660
uniprot id: A0A3S6F1R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RavA family.
messages: Cytoplasm
messages: Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone.

935293:PL78 RS08820
gene id: 935293:PL78_RS08820
uniprot id: A0A3S6F0P6
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

935293:PL78 RS12815
gene id: 935293:PL78_RS12815
uniprot id: A0A3S6F1Y5
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

935293:PL78 RS14825
gene id: 935293:PL78_RS14825
uniprot id: A0A3S6F372
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

935293:PL78 RS13195
gene id: 935293:PL78_RS13195
uniprot id: A0A3S6F212
names: Similarity
messages: Belongs to the UPF0213 family.

935293:PL78 RS17380
gene id: 935293:PL78_RS17380
uniprot id: A0A3S6F4P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CitD family.
messages: Covalent carrier of the coenzyme of citrate lyase.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.

935293:PL78 RS18375
gene id: 935293:PL78_RS18375
uniprot id: A0A3S6F501
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

935293:PL78 RS11320
gene id: 935293:PL78_RS11320
uniprot id: A0A3S6F230
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

935293:PL78 RS15515
gene id: 935293:PL78_RS15515
uniprot id: A0A3S6F3C1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Probably plays an important role in intracellular peptide degradation.

935293:PL78 RS13185
gene id: 935293:PL78_RS13185
uniprot id: A0A3S6F295
names: Function
names: Similarity
messages: Belongs to the UbiT family.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor.

935293:PL78 RS04920
gene id: 935293:PL78_RS04920
uniprot id: A0A3S6EXQ1
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

935293:PL78 RS02540
gene id: 935293:PL78_RS02540
uniprot id: A0A3S6EW63
names: Subcellular Location Annotation
messages: Cytoplasm

935293:PL78 RS02250
gene id: 935293:PL78_RS02250
uniprot id: A0A3S6EW18
names: Similarity
messages: Belongs to the UDPGP type 2 family.

935293:PL78 RS17955
gene id: 935293:PL78_RS17955
uniprot id: A0A3S6F6C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

935293:PL78 RS12750
gene id: 935293:PL78_RS12750
uniprot id: A0A3S6F1X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

935293:PL78 RS02620
gene id: 935293:PL78_RS02620
uniprot id: A0A3S6EWP5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

935293:PL78 RS11390
gene id: 935293:PL78_RS11390
uniprot id: A0A3S6F113
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

935293:PL78 RS14500
gene id: 935293:PL78_RS14500
uniprot id: A0A3S6F2X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

935293:PL78 RS09970
gene id: 935293:PL78_RS09970
uniprot id: A0A3S6F0B6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

935293:PL78 RS12980
gene id: 935293:PL78_RS12980
uniprot id: A0A3S6F1W9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS01635
gene id: 935293:PL78_RS01635
uniprot id: A0A3S6EVM7
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 zinc ion per subunit.

935293:PL78 RS05175
gene id: 935293:PL78_RS05175
uniprot id: A0A3S6EY43
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

935293:PL78 RS04125
gene id: 935293:PL78_RS04125
uniprot id: A0A3S6EYP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

935293:PL78 RS00665
gene id: 935293:PL78_RS00665
uniprot id: A0A3S6EV24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

935293:PL78 RS06155
gene id: 935293:PL78_RS06155
uniprot id: A0A3S6EYM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Vitamin B12 importer (TC 3.A.1.13.1) family.
messages: Cell membrane
messages: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).

935293:PL78 RS04800
gene id: 935293:PL78_RS04800
uniprot id: A0A3S6EXH5
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

935293:PL78 RS08385
gene id: 935293:PL78_RS08385
uniprot id: A0A3S6EZG7
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS14800
gene id: 935293:PL78_RS14800
uniprot id: A0A3S6F2X7
names: Subcellular Location Annotation
messages: Cytoplasm

935293:PL78 RS17245
gene id: 935293:PL78_RS17245
uniprot id: A0A3S6F4E4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

935293:PL78 RS10540
gene id: 935293:PL78_RS10540
uniprot id: A0A3S6F0P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.
messages: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

935293:PL78 RS17465
gene id: 935293:PL78_RS17465
uniprot id: A0A3S6F4D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HdeB family.
messages: Periplasm
messages: Required for optimal acid stress protection, which is important for survival of enteric bacteria in the acidic environment of the host stomach. Exhibits a chaperone-like activity at acidic pH by preventing the aggregation of many different periplasmic proteins.

935293:PL78 RS16360
gene id: 935293:PL78_RS16360
uniprot id: A0A3S6F3U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

935293:PL78 RS12620
gene id: 935293:PL78_RS12620
uniprot id: A0A3S6F1U8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

935293:PL78 RS02280
gene id: 935293:PL78_RS02280
uniprot id: A0A3S6EWF4
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.

935293:PL78 RS15495
gene id: 935293:PL78_RS15495
uniprot id: A0A3S6F4C8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity. Interacts with IscU.

935293:PL78 RS05540
gene id: 935293:PL78_RS05540
uniprot id: A0A3S6EXV1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

935293:PL78 RS05990
gene id: 935293:PL78_RS05990
uniprot id: A0A3S6EY62
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
messages: Belongs to the Lpp family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: cell wall

935293:PL78 RS14235
gene id: 935293:PL78_RS14235
uniprot id: A0A3S6F2K9
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

935293:PL78 RS04755
gene id: 935293:PL78_RS04755
uniprot id: A0A3S6EXF1
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

935293:PL78 RS17610
gene id: 935293:PL78_RS17610
uniprot id: A0A3S6F656
names: Similarity
messages: Belongs to the peptidase S8 family.

935293:PL78 RS16455
gene id: 935293:PL78_RS16455
uniprot id: A0A3S6F461
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

935293:PL78 RS08060
gene id: 935293:PL78_RS08060
uniprot id: A0A3S6F0S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

935293:PL78 RS14410
gene id: 935293:PL78_RS14410
uniprot id: A0A3S6F2Z1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.

935293:PL78 RS01285
gene id: 935293:PL78_RS01285
uniprot id: A0A3S6EVW7
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS16520
gene id: 935293:PL78_RS16520
uniprot id: A0A3S6F5G8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS08360
gene id: 935293:PL78_RS08360
uniprot id: A0A3S6F0Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

935293:PL78 RS06015
gene id: 935293:PL78_RS06015
uniprot id: A0A3S6EZN8
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

935293:PL78 RS07955
gene id: 935293:PL78_RS07955
uniprot id: A0A3S6EZI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

935293:PL78 RS06110
gene id: 935293:PL78_RS06110
uniprot id: A0A3S6EY49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArnF family.
messages: Cell inner membrane
messages: Heterodimer of ArnE and ArnF.
messages: Membrane
messages: Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.

935293:PL78 RS13595
gene id: 935293:PL78_RS13595
uniprot id: A0A3S6F2D2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.
messages: The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.

935293:PL78 RS08545
gene id: 935293:PL78_RS08545
uniprot id: A0A3S6EZI0
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

935293:PL78 RS07800
gene id: 935293:PL78_RS07800
uniprot id: A0A3S6EZ13
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M20A family. ArgE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids. Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.
messages: Cytoplasm
messages: Homodimer.

935293:PL78 RS15510
gene id: 935293:PL78_RS15510
uniprot id: A0A3S6F3M8
names: Function
names: Similarity
messages: Belongs to the IscX family.
messages: May function as iron donor in the assembly of iron-sulfur clusters.

935293:PL78 RS12200
gene id: 935293:PL78_RS12200
uniprot id: A0A3S6F1X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

935293:PL78 RS01275
gene id: 935293:PL78_RS01275
uniprot id: A0A3S6EVY0
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

935293:PL78 RS07575
gene id: 935293:PL78_RS07575
uniprot id: A0A3S6F0H1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

935293:PL78 RS06170
gene id: 935293:PL78_RS06170
uniprot id: A0A3S6EZR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

935293:PL78 RS11790
gene id: 935293:PL78_RS11790
uniprot id: A0A3S6F191
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GlpE family.
messages: Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
messages: Cytoplasm

935293:PL78 RS14490
gene id: 935293:PL78_RS14490
uniprot id: A0A3S6F2V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

935293:PL78 RS05960
gene id: 935293:PL78_RS05960
uniprot id: A0A3S6EY48
names: Function
messages: Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.

935293:PL78 RS04980
gene id: 935293:PL78_RS04980
uniprot id: A0A3S6EXJ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

935293:PL78 RS10410
gene id: 935293:PL78_RS10410
uniprot id: A0A3S6F0X3
names: Function
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.

935293:PL78 RS08640
gene id: 935293:PL78_RS08640
uniprot id: A0A3S6EZG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

935293:PL78 RS13790
gene id: 935293:PL78_RS13790
uniprot id: A0A3S6F2D9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

935293:PL78 RS01465
gene id: 935293:PL78_RS01465
uniprot id: A0A3S6EVK3
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

935293:PL78 RS07845
gene id: 935293:PL78_RS07845
uniprot id: A0A3S6EZI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsN family.
messages: Cell inner membrane
messages: Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.
messages: Interacts with FtsA via its N-terminal cytoplasmic domain.

935293:PL78 RS07070
gene id: 935293:PL78_RS07070
uniprot id: A0A3S6EYQ6
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

935293:PL78 RS16235
gene id: 935293:PL78_RS16235
uniprot id: A0A3S6F4R8
names: Similarity
messages: Belongs to the YjdM family.

935293:PL78 RS10965
gene id: 935293:PL78_RS10965
uniprot id: A0A3S6F2G5
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

935293:PL78 RS00295
gene id: 935293:PL78_RS00295
uniprot id: A0A3S6EWK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

935293:PL78 RS05995
gene id: 935293:PL78_RS05995
uniprot id: A0A3S6EYA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YkuD family.
messages: Periplasm

935293:PL78 RS16415
gene id: 935293:PL78_RS16415
uniprot id: A0A3S6F484
names: Similarity
messages: Belongs to the UPF0115 family.

935293:PL78 RS15780
gene id: 935293:PL78_RS15780
uniprot id: A0A3S6F530
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

935293:PL78 RS03260
gene id: 935293:PL78_RS03260
uniprot id: A0A3S6EXM9
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family. NagK subfamily.
messages: Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.

935293:PL78 RS04910
gene id: 935293:PL78_RS04910
uniprot id: A0A3S6EYK7
names: Similarity
messages: Belongs to the YciI family.

935293:PL78 RS15850
gene id: 935293:PL78_RS15850
uniprot id: A0A3S6F4K0
names: Similarity
messages: Belongs to the ArsC family.

935293:PL78 RS10820
gene id: 935293:PL78_RS10820
uniprot id: A0A3S6F0P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family. LpxP subfamily.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(acyl)-lipid IV(A).
messages: Cell inner membrane

935293:PL78 RS04665
gene id: 935293:PL78_RS04665
uniprot id: A0A3S6EXU5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

935293:PL78 RS12665
gene id: 935293:PL78_RS12665
uniprot id: A0A3S6F1S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the low-affinity transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

935293:PL78 RS16720
gene id: 935293:PL78_RS16720
uniprot id: A0A3S6F5K7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

935293:PL78 RS17195
gene id: 935293:PL78_RS17195
uniprot id: A0A3S6F4B9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS13630
gene id: 935293:PL78_RS13630
uniprot id: A0A3S6F3W0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

935293:PL78 RS17150
gene id: 935293:PL78_RS17150
uniprot id: A0A3S6F4C3
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

935293:PL78 RS12375
gene id: 935293:PL78_RS12375
uniprot id: A0A3S6F2P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.
messages: Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
messages: Cytoplasm
messages: Homodimer.

935293:PL78 RS15000
gene id: 935293:PL78_RS15000
uniprot id: A0A3S6F3A0
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS16565
gene id: 935293:PL78_RS16565
uniprot id: A0A3S6F4B7
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS13955
gene id: 935293:PL78_RS13955
uniprot id: A0A3S6F2L4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

935293:PL78 RS08630
gene id: 935293:PL78_RS08630
uniprot id: A0A3S6EZW4
names: Similarity
messages: Belongs to the skp family.

935293:PL78 RS03320
gene id: 935293:PL78_RS03320
uniprot id: A0A3S6EWM7
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

935293:PL78 RS16810
gene id: 935293:PL78_RS16810
uniprot id: A0A3S6F434
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

935293:PL78 RS03175
gene id: 935293:PL78_RS03175
uniprot id: A0A3S6EX05
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

935293:PL78 RS04635
gene id: 935293:PL78_RS04635
uniprot id: A0A3S6EXD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
messages: Cell membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

935293:PL78 RS15915
gene id: 935293:PL78_RS15915
uniprot id: A0A3S6F3V7
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

935293:PL78 RS10390
gene id: 935293:PL78_RS10390
uniprot id: A0A3S6F0L3
names: Similarity
messages: Belongs to the UPF0102 family.

935293:PL78 RS19065
gene id: 935293:PL78_RS19065
uniprot id: A0A3S6F5E3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class B bacterial acid phosphatase family.
messages: Homotetramer.
messages: Periplasm

935293:PL78 RS02110
gene id: 935293:PL78_RS02110
uniprot id: A0A3S6EVY7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

935293:PL78 RS01945
gene id: 935293:PL78_RS01945
uniprot id: A0A3S6EVV2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

935293:PL78 RS16365
gene id: 935293:PL78_RS16365
uniprot id: A0A3S6F474
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS11045
gene id: 935293:PL78_RS11045
uniprot id: A0A3S6F143
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MalK), two transmembrane proteins (MalG and MalF) and a solute-binding protein (MalE).

935293:PL78 RS12600
gene id: 935293:PL78_RS12600
uniprot id: A0A3S6F257
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

935293:PL78 RS08015
gene id: 935293:PL78_RS08015
uniprot id: A0A3S6EZ58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

935293:PL78 RS05620
gene id: 935293:PL78_RS05620
uniprot id: A0A3S6EYZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS17830
gene id: 935293:PL78_RS17830
uniprot id: A0A3S6F5R4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
messages: Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine.
messages: Homodimer.

935293:PL78 RS09795
gene id: 935293:PL78_RS09795
uniprot id: A0A3S6F0F8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

935293:PL78 RS01690
gene id: 935293:PL78_RS01690
uniprot id: A0A3S6EVN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

935293:PL78 RS16725
gene id: 935293:PL78_RS16725
uniprot id: A0A3S6F3Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

935293:PL78 RS07440
gene id: 935293:PL78_RS07440
uniprot id: A0A3S6EZC0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD, in which XerC interacts with XerD via its C-terminal region, XerD interacts with XerC via its C-terminal region and so on.
messages: FtsK may regulate the catalytic switch between XerC and XerD in the heterotetrameric complex during the two steps of the recombination process.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC specifically exchanges the top DNA strands.

935293:PL78 RS01520
gene id: 935293:PL78_RS01520
uniprot id: A0A3S6EVT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

935293:PL78 RS05835
gene id: 935293:PL78_RS05835
uniprot id: A0A3S6EYH3
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

935293:PL78 RS13725
gene id: 935293:PL78_RS13725
uniprot id: A0A3S6F2Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

935293:PL78 RS04745
gene id: 935293:PL78_RS04745
uniprot id: A0A3S6EXE7
names: Similarity
messages: Belongs to the asparaginase 1 family.

935293:PL78 RS00535
gene id: 935293:PL78_RS00535
uniprot id: A0A3S6EUZ8
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

935293:PL78 RS13920
gene id: 935293:PL78_RS13920
uniprot id: A0A3S6F2E8
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS17230
gene id: 935293:PL78_RS17230
uniprot id: A0A3S6F5Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

935293:PL78 RS14680
gene id: 935293:PL78_RS14680
uniprot id: A0A3S6F2V6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm
messages: Homotetramer.

935293:PL78 RS06860
gene id: 935293:PL78_RS06860
uniprot id: A0A3S6F048
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rsd/AlgQ family.
messages: Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.
messages: Cytoplasm
messages: Interacts with RpoD.

935293:PL78 RS12290
gene id: 935293:PL78_RS12290
uniprot id: A0A3S6F1Y1
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

935293:PL78 RS00405
gene id: 935293:PL78_RS00405
uniprot id: A0A3S6EUW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

935293:PL78 RS12575
gene id: 935293:PL78_RS12575
uniprot id: A0A3S6F2T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

935293:PL78 RS16885
gene id: 935293:PL78_RS16885
uniprot id: A0A3S6F475
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I11 (ecotin) family.
messages: General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases.
messages: Homodimer.
messages: Periplasm

935293:PL78 RS12835
gene id: 935293:PL78_RS12835
uniprot id: A0A3S6F298
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm
messages: Monomer.

935293:PL78 RS09665
gene id: 935293:PL78_RS09665
uniprot id: A0A3S6F1P6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

935293:PL78 RS17215
gene id: 935293:PL78_RS17215
uniprot id: A0A3S6F4L7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS13335
gene id: 935293:PL78_RS13335
uniprot id: A0A3S6F2C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraB family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
messages: Interacts with the C-terminal region of Rne.

935293:PL78 RS10740
gene id: 935293:PL78_RS10740
uniprot id: A0A3S6F0S6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

935293:PL78 RS08610
gene id: 935293:PL78_RS08610
uniprot id: A0A3S6EZK8
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

935293:PL78 RS17570
gene id: 935293:PL78_RS17570
uniprot id: A0A3S6F4I7
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

935293:PL78 RS14315
gene id: 935293:PL78_RS14315
uniprot id: A0A3S6F2Z7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

935293:PL78 RS07740
gene id: 935293:PL78_RS07740
uniprot id: A0A3S6EZ90
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

935293:PL78 RS07525
gene id: 935293:PL78_RS07525
uniprot id: A0A3S6F0G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 56 family.
messages: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis.
messages: Cell inner membrane

935293:PL78 RS12915
gene id: 935293:PL78_RS12915
uniprot id: A0A3S6F211
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

935293:PL78 RS05205
gene id: 935293:PL78_RS05205
uniprot id: A0A3S6EXP1
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS14400
gene id: 935293:PL78_RS14400
uniprot id: A0A3S6F3T0
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

935293:PL78 RS01515
gene id: 935293:PL78_RS01515
uniprot id: A0A3S6EVL4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

935293:PL78 RS09205
gene id: 935293:PL78_RS09205
uniprot id: A0A3S6F079
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

935293:PL78 RS02680
gene id: 935293:PL78_RS02680
uniprot id: A0A3S6EWN1
names: Similarity
messages: Belongs to the 2-oxoadipate dioxygenase/decarboxylase family.

935293:PL78 RS03000
gene id: 935293:PL78_RS03000
uniprot id: A0A3S6EWG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

935293:PL78 RS12465
gene id: 935293:PL78_RS12465
uniprot id: A0A3S6F1P3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

935293:PL78 RS08225
gene id: 935293:PL78_RS08225
uniprot id: A0A3S6EZC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

935293:PL78 RS12975
gene id: 935293:PL78_RS12975
uniprot id: A0A3S6F2A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

935293:PL78 RS16605
gene id: 935293:PL78_RS16605
uniprot id: A0A3S6F493
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

935293:PL78 RS14815
gene id: 935293:PL78_RS14815
uniprot id: A0A3S6F401
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery.

935293:PL78 RS00795
gene id: 935293:PL78_RS00795
uniprot id: A0A3S6EV55
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

935293:PL78 RS00555
gene id: 935293:PL78_RS00555
uniprot id: A0A3S6EV06
names: Similarity
messages: Belongs to the Hha/YmoA/Cnu family.

935293:PL78 RS10885
gene id: 935293:PL78_RS10885
uniprot id: A0A3S6F1U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

935293:PL78 RS04495
gene id: 935293:PL78_RS04495
uniprot id: A0A3S6EX95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M23B family.
messages: Membrane

935293:PL78 RS09385
gene id: 935293:PL78_RS09385
uniprot id: A0A3S6F012
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
messages: Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS01900
gene id: 935293:PL78_RS01900
uniprot id: A0A3S6EWW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

935293:PL78 RS15795
gene id: 935293:PL78_RS15795
uniprot id: A0A3S6F3K4
names: Subcellular Location Annotation
messages: Cytoplasm

935293:PL78 RS19100
gene id: 935293:PL78_RS19100
uniprot id: A0A3S6F7B9
names: Similarity
messages: Belongs to the MT-A70-like family.

935293:PL78 RS14395
gene id: 935293:PL78_RS14395
uniprot id: A0A3S6F2T7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS15815
gene id: 935293:PL78_RS15815
uniprot id: A0A3S6F3T9
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS18175
gene id: 935293:PL78_RS18175
uniprot id: A0A3S6F4R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS08145
gene id: 935293:PL78_RS08145
uniprot id: A0A3S6EZP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane

935293:PL78 RS14015
gene id: 935293:PL78_RS14015
uniprot id: A0A3S6F2U3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

935293:PL78 RS05650
gene id: 935293:PL78_RS05650
uniprot id: A0A3S6EZH9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M14 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in muropeptide degradation. Catalyzes the hydrolysis of the gamma-D-glutamyl-diaminopimelic acid (gamma-D-Glu-Dap) amide bond in the murein tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelic acid, leading to the formation of L-Ala-gamma-D-Glu and Dap.

935293:PL78 RS07625
gene id: 935293:PL78_RS07625
uniprot id: A0A3S6F0I2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS13245
gene id: 935293:PL78_RS13245
uniprot id: A0A3S6F222
names: Function
names: Similarity
messages: Belongs to the PhnJ family.
messages: Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose.

935293:PL78 RS12745
gene id: 935293:PL78_RS12745
uniprot id: A0A3S6F2W2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

935293:PL78 RS10585
gene id: 935293:PL78_RS10585
uniprot id: A0A3S6F1N8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

935293:PL78 RS15810
gene id: 935293:PL78_RS15810
uniprot id: A0A3S6F3Q2
names: Similarity
messages: Belongs to the SAICAR synthetase family.

935293:PL78 RS06720
gene id: 935293:PL78_RS06720
uniprot id: A0A3S6EYG8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

935293:PL78 RS07320
gene id: 935293:PL78_RS07320
uniprot id: A0A3S6EYV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

935293:PL78 RS13225
gene id: 935293:PL78_RS13225
uniprot id: A0A3S6F358
names: Function
names: Similarity
messages: Belongs to the ribose 1,5-bisphosphokinase family.
messages: Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).

935293:PL78 RS18450
gene id: 935293:PL78_RS18450
uniprot id: A0A3S6F4Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HdeB family.
messages: Periplasm
messages: Required for optimal acid stress protection, which is important for survival of enteric bacteria in the acidic environment of the host stomach. Exhibits a chaperone-like activity at acidic pH by preventing the aggregation of many different periplasmic proteins.

935293:PL78 RS09860
gene id: 935293:PL78_RS09860
uniprot id: A0A3S6F0K6
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

935293:PL78 RS17665
gene id: 935293:PL78_RS17665
uniprot id: A0A3S6F4H1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

935293:PL78 RS15050
gene id: 935293:PL78_RS15050
uniprot id: A0A3S6F3A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
messages: Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.
messages: Cell membrane

935293:PL78 RS13680
gene id: 935293:PL78_RS13680
uniprot id: A0A3S6F3X1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

935293:PL78 RS02425
gene id: 935293:PL78_RS02425
uniprot id: A0A3S6EW32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

935293:PL78 RS00520
gene id: 935293:PL78_RS00520
uniprot id: A0A3S6EV03
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS12525
gene id: 935293:PL78_RS12525
uniprot id: A0A3S6F2S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

935293:PL78 RS07325
gene id: 935293:PL78_RS07325
uniprot id: A0A3S6EZW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

935293:PL78 RS13065
gene id: 935293:PL78_RS13065
uniprot id: A0A3S6F242
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

935293:PL78 RS16635
gene id: 935293:PL78_RS16635
uniprot id: A0A3S6F424
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

935293:PL78 RS11055
gene id: 935293:PL78_RS11055
uniprot id: A0A3S6F0V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

935293:PL78 RS01785
gene id: 935293:PL78_RS01785
uniprot id: A0A3S6EVQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

935293:PL78 RS06105
gene id: 935293:PL78_RS06105
uniprot id: A0A3S6EYL9
names: Similarity
messages: Belongs to the peptidase C40 family.

935293:PL78 RS12115
gene id: 935293:PL78_RS12115
uniprot id: A0A3S6F1K5
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

935293:PL78 RS09715
gene id: 935293:PL78_RS09715
uniprot id: A0A3S6F1Q7
names: Cofactor
messages: Binds 1 phosphopantetheine covalently.

935293:PL78 RS07120
gene id: 935293:PL78_RS07120
uniprot id: A0A3S6EYR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

935293:PL78 RS05795
gene id: 935293:PL78_RS05795
uniprot id: A0A3S6EYC4
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS09420
gene id: 935293:PL78_RS09420
uniprot id: A0A3S6F003
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

935293:PL78 RS15655
gene id: 935293:PL78_RS15655
uniprot id: A0A3S6F3J8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.
messages: Binds 1 Mg(2+) ion per subunit. Ca(2+) may be able to substitute.
messages: Cytoplasm
messages: Probably phosphorylates lipids; the in vivo substrate is unknown.

935293:PL78 RS11380
gene id: 935293:PL78_RS11380
uniprot id: A0A3S6F1A1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

935293:PL78 RS18620
gene id: 935293:PL78_RS18620
uniprot id: A0A3S6F691
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport.

935293:PL78 RS05925
gene id: 935293:PL78_RS05925
uniprot id: A0A3S6EY53
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.
messages: Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters.

935293:PL78 RS07655
gene id: 935293:PL78_RS07655
uniprot id: A0A3S6EZ81
names: Similarity
messages: Belongs to the UPF0438 family.

935293:PL78 RS08920
gene id: 935293:PL78_RS08920
uniprot id: A0A3S6F0R5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS12295
gene id: 935293:PL78_RS12295
uniprot id: A0A3S6F1J1
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Membrane

935293:PL78 RS18610
gene id: 935293:PL78_RS18610
uniprot id: A0A3S6F552
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS01510
gene id: 935293:PL78_RS01510
uniprot id: A0A3S6EWN7
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

935293:PL78 RS04685
gene id: 935293:PL78_RS04685
uniprot id: A0A3S6EXE3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS12690
gene id: 935293:PL78_RS12690
uniprot id: A0A3S6F256
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

935293:PL78 RS08215
gene id: 935293:PL78_RS08215
uniprot id: A0A3S6EZA1
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

935293:PL78 RS02685
gene id: 935293:PL78_RS02685
uniprot id: A0A3S6EXW7
names: Subcellular Location Annotation
messages: Cytoplasm

935293:PL78 RS13885
gene id: 935293:PL78_RS13885
uniprot id: A0A3S6F2E1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

935293:PL78 RS08340
gene id: 935293:PL78_RS08340
uniprot id: A0A3S6EZM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

935293:PL78 RS04810
gene id: 935293:PL78_RS04810
uniprot id: A0A3S6EYI5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS04930
gene id: 935293:PL78_RS04930
uniprot id: A0A3S6EXI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

935293:PL78 RS03210
gene id: 935293:PL78_RS03210
uniprot id: A0A3S6EXL9
names: Similarity
messages: Belongs to the UPF0227 family.

935293:PL78 RS02725
gene id: 935293:PL78_RS02725
uniprot id: A0A3S6EW92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MukE family.
messages: Interacts, and probably forms a ternary complex, with MukF and MukB. The complex formation is stimulated by calcium or magnesium.
messages: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.
messages: nucleoid

935293:PL78 RS04365
gene id: 935293:PL78_RS04365
uniprot id: A0A3S6EXD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.
messages: Cell membrane
messages: Membrane

935293:PL78 RS17925
gene id: 935293:PL78_RS17925
uniprot id: A0A3S6F5T3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

935293:PL78 RS02150
gene id: 935293:PL78_RS02150
uniprot id: A0A3S6EVZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

935293:PL78 RS08055
gene id: 935293:PL78_RS08055
uniprot id: A0A3S6EZK2
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

935293:PL78 RS16535
gene id: 935293:PL78_RS16535
uniprot id: A0A3S6F404
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS02900
gene id: 935293:PL78_RS02900
uniprot id: A0A3S6EWF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HspQ family.
messages: Cytoplasm
messages: Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress.

935293:PL78 RS17080
gene id: 935293:PL78_RS17080
uniprot id: A0A3S6F4L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS18165
gene id: 935293:PL78_RS18165
uniprot id: A0A3S6F581
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

935293:PL78 RS04450
gene id: 935293:PL78_RS04450
uniprot id: A0A3S6EYB7
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

935293:PL78 RS17795
gene id: 935293:PL78_RS17795
uniprot id: A0A3S6F4Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

935293:PL78 RS03155
gene id: 935293:PL78_RS03155
uniprot id: A0A3S6EWJ0
names: Similarity
names: Subunit
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

935293:PL78 RS10495
gene id: 935293:PL78_RS10495
uniprot id: A0A3S6F0U7
names: Similarity
messages: Belongs to the BolA/IbaG family.

935293:PL78 RS18455
gene id: 935293:PL78_RS18455
uniprot id: A0A3S6F5D8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

935293:PL78 RS17480
gene id: 935293:PL78_RS17480
uniprot id: A0A3S6F5H2
names: Subcellular Location Annotation
messages: Cytoplasm

935293:PL78 RS07995
gene id: 935293:PL78_RS07995
uniprot id: A0A3S6EZL3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

935293:PL78 RS08070
gene id: 935293:PL78_RS08070
uniprot id: A0A3S6EZ84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

935293:PL78 RS08370
gene id: 935293:PL78_RS08370
uniprot id: A0A3S6EZE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

935293:PL78 RS13685
gene id: 935293:PL78_RS13685
uniprot id: A0A3S6F2A4
names: Caution
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. GpmB subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS09570
gene id: 935293:PL78_RS09570
uniprot id: A0A3S6EZZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

935293:PL78 RS08865
gene id: 935293:PL78_RS08865
uniprot id: A0A3S6EZP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MutH family.
messages: Cytoplasm
messages: Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.

935293:PL78 RS10600
gene id: 935293:PL78_RS10600
uniprot id: A0A3S6F107
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS06440
gene id: 935293:PL78_RS06440
uniprot id: A0A3S6EYC2
names: Similarity
messages: Belongs to the MT-A70-like family.

935293:PL78 RS05110
gene id: 935293:PL78_RS05110
uniprot id: A0A3S6EYP7
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

935293:PL78 RS05930
gene id: 935293:PL78_RS05930
uniprot id: A0A3S6EY97
names: Similarity
messages: Belongs to the peptidase C40 family.

935293:PL78 RS18510
gene id: 935293:PL78_RS18510
uniprot id: A0A3S6F6S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

935293:PL78 RS06505
gene id: 935293:PL78_RS06505
uniprot id: A0A3S6EYG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

935293:PL78 RS04760
gene id: 935293:PL78_RS04760
uniprot id: A0A3S6EXM0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

935293:PL78 RS02860
gene id: 935293:PL78_RS02860
uniprot id: A0A3S6EWD6
names: Function
names: Induction
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the SulA family.
messages: By DNA damage, as part of the SOS response.
messages: Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
messages: Interacts with FtsZ.
messages: Is rapidly cleaved and degraded by the Lon protease once DNA damage is repaired.

935293:PL78 RS03910
gene id: 935293:PL78_RS03910
uniprot id: A0A3S6EXB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

935293:PL78 RS13210
gene id: 935293:PL78_RS13210
uniprot id: A0A3S6F214
names: Similarity
messages: Belongs to the UPF0306 family.

935293:PL78 RS20215
gene id: 935293:PL78_RS20215
uniprot id: A0A3S6F002
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

935293:PL78 RS15540
gene id: 935293:PL78_RS15540
uniprot id: A0A3S6F3G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

935293:PL78 RS02475
gene id: 935293:PL78_RS02475
uniprot id: A0A3S6EW40
names: Similarity
messages: Belongs to the UPF0145 family.

935293:PL78 RS18150
gene id: 935293:PL78_RS18150
uniprot id: A0A3S6F500
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.

935293:PL78 RS10405
gene id: 935293:PL78_RS10405
uniprot id: A0A3S6F0H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

935293:PL78 RS14820
gene id: 935293:PL78_RS14820
uniprot id: A0A3S6F334
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

935293:PL78 RS15465
gene id: 935293:PL78_RS15465
uniprot id: A0A3S6F3B1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

935293:PL78 RS06085
gene id: 935293:PL78_RS06085
uniprot id: A0A3S6EY75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

935293:PL78 RS03250
gene id: 935293:PL78_RS03250
uniprot id: A0A3S6EWM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

935293:PL78 RS15260
gene id: 935293:PL78_RS15260
uniprot id: A0A3S6F3H4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

935293:PL78 RS02840
gene id: 935293:PL78_RS02840
uniprot id: A0A3S6EWC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

935293:PL78 RS00845
gene id: 935293:PL78_RS00845
uniprot id: A0A3S6EV65
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS16905
gene id: 935293:PL78_RS16905
uniprot id: A0A3S6F4F6
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

935293:PL78 RS07805
gene id: 935293:PL78_RS07805
uniprot id: A0A3S6EZE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

935293:PL78 RS08285
gene id: 935293:PL78_RS08285
uniprot id: A0A3S6EZF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

935293:PL78 RS02105
gene id: 935293:PL78_RS02105
uniprot id: A0A3S6EWZ8
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

935293:PL78 RS01915
gene id: 935293:PL78_RS01915
uniprot id: A0A3S6EWA6
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS09775
gene id: 935293:PL78_RS09775
uniprot id: A0A3S6F075
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

935293:PL78 RS07050
gene id: 935293:PL78_RS07050
uniprot id: A0A3S6EZ00
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

935293:PL78 RS09150
gene id: 935293:PL78_RS09150
uniprot id: A0A3S6EZS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

935293:PL78 RS02945
gene id: 935293:PL78_RS02945
uniprot id: A0A3S6EWE9
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

935293:PL78 RS17640
gene id: 935293:PL78_RS17640
uniprot id: A0A3S6F4Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

935293:PL78 RS11385
gene id: 935293:PL78_RS11385
uniprot id: A0A3S6F1F6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

935293:PL78 RS16670
gene id: 935293:PL78_RS16670
uniprot id: A0A3S6F5J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 5DNU family.
messages: Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
messages: Cytoplasm
messages: Homodimer.

935293:PL78 RS15885
gene id: 935293:PL78_RS15885
uniprot id: A0A3S6F3H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapF family.
messages: Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

935293:PL78 RS07650
gene id: 935293:PL78_RS07650
uniprot id: A0A3S6EZ27
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

935293:PL78 RS05365
gene id: 935293:PL78_RS05365
uniprot id: A0A3S6EYU6
names: Similarity
messages: Belongs to the group II decarboxylase family.

935293:PL78 RS09600
gene id: 935293:PL78_RS09600
uniprot id: A0A3S6F0G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefC subfamily.
messages: Cell inner membrane
messages: Homodimer. Interacts with the regulatory subunit KefF.
messages: Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.

935293:PL78 RS06940
gene id: 935293:PL78_RS06940
uniprot id: A0A3S6EYU3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS10775
gene id: 935293:PL78_RS10775
uniprot id: A0A3S6F0T1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

935293:PL78 RS07615
gene id: 935293:PL78_RS07615
uniprot id: A0A3S6EYY2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS02735
gene id: 935293:PL78_RS02735
uniprot id: A0A3S6EXX6
names: Similarity
messages: Belongs to the YkuD family.

935293:PL78 RS05820
gene id: 935293:PL78_RS05820
uniprot id: A0A3S6EZ36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

935293:PL78 RS11040
gene id: 935293:PL78_RS11040
uniprot id: A0A3S6F0Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins.
messages: Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import. Binds G3P.
messages: Periplasm
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

935293:PL78 RS15675
gene id: 935293:PL78_RS15675
uniprot id: A0A3S6F3U6
names: Subcellular Location Annotation
messages: Cell inner membrane

935293:PL78 RS05140
gene id: 935293:PL78_RS05140
uniprot id: A0A3S6EZ96
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

935293:PL78 RS11955
gene id: 935293:PL78_RS11955
uniprot id: A0A3S6F1E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cdh family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS15360
gene id: 935293:PL78_RS15360
uniprot id: A0A3S6F3K0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

935293:PL78 RS10455
gene id: 935293:PL78_RS10455
uniprot id: A0A3S6F0I7
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

935293:PL78 RS10305
gene id: 935293:PL78_RS10305
uniprot id: A0A3S6F0U9
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS17205
gene id: 935293:PL78_RS17205
uniprot id: A0A3S6F4E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

935293:PL78 RS06190
gene id: 935293:PL78_RS06190
uniprot id: A0A3S6EZA4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

935293:PL78 RS12460
gene id: 935293:PL78_RS12460
uniprot id: A0A3S6F1M7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

935293:PL78 RS10415
gene id: 935293:PL78_RS10415
uniprot id: A0A3S6F249
names: PTM
names: Subcellular Location Annotation
messages: Activation requires a sequential transfer of a phosphate group from a His in the primary transmitter domain, to an Asp in the receiver domain and to a His in the secondary transmitter domain.
messages: Cell inner membrane

935293:PL78 RS06180
gene id: 935293:PL78_RS06180
uniprot id: A0A3S6EY90
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

935293:PL78 RS00675
gene id: 935293:PL78_RS00675
uniprot id: A0A3S6EW84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

935293:PL78 RS17065
gene id: 935293:PL78_RS17065
uniprot id: A0A3S6F4E0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

935293:PL78 RS02345
gene id: 935293:PL78_RS02345
uniprot id: A0A3S6EW27
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

935293:PL78 RS05575
gene id: 935293:PL78_RS05575
uniprot id: A0A3S6EXW1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

935293:PL78 RS06885
gene id: 935293:PL78_RS06885
uniprot id: A0A3S6EYN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

935293:PL78 RS10945
gene id: 935293:PL78_RS10945
uniprot id: A0A3S6F124
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

935293:PL78 RS01260
gene id: 935293:PL78_RS01260
uniprot id: A0A3S6EWI7
names: Similarity
messages: Belongs to the asparagine synthetase family.

935293:PL78 RS19020
gene id: 935293:PL78_RS19020
uniprot id: A0A3S6F6G7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

935293:PL78 RS13610
gene id: 935293:PL78_RS13610
uniprot id: A0A3S6F2I1
names: Similarity
messages: Belongs to the Smp family.

935293:PL78 RS11000
gene id: 935293:PL78_RS11000
uniprot id: A0A3S6F188
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

935293:PL78 RS00775
gene id: 935293:PL78_RS00775
uniprot id: A0A3S6EWA3
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the phosphorylation of guanosine and inosine to GMP and IMP, respectively.

935293:PL78 RS01795
gene id: 935293:PL78_RS01795
uniprot id: A0A3S6EVS0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS04290
gene id: 935293:PL78_RS04290
uniprot id: A0A3S6EX57
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

935293:PL78 RS16190
gene id: 935293:PL78_RS16190
uniprot id: A0A3S6F3U7
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS05010
gene id: 935293:PL78_RS05010
uniprot id: A0A3S6EYM6
names: Similarity
messages: Belongs to the peptidase S49 family.

935293:PL78 RS10670
gene id: 935293:PL78_RS10670
uniprot id: A0A3S6F0L4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cytochrome b562 family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per molecule.
messages: Electron-transport protein of unknown function.

935293:PL78 RS02845
gene id: 935293:PL78_RS02845
uniprot id: A0A3S6EWD3
names: Similarity
messages: Belongs to the peptidase S16 family.

935293:PL78 RS17535
gene id: 935293:PL78_RS17535
uniprot id: A0A3S6F4J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.
messages: Membrane

935293:PL78 RS13970
gene id: 935293:PL78_RS13970
uniprot id: A0A3S6F2G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AlaE exporter family.
messages: Cell inner membrane
messages: Exports L-alanine.

935293:PL78 RS08270
gene id: 935293:PL78_RS08270
uniprot id: A0A3S6EZC3
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

935293:PL78 RS01835
gene id: 935293:PL78_RS01835
uniprot id: A0A3S6EVR8
names: Similarity
messages: Belongs to the peptidase S11 family.

935293:PL78 RS07185
gene id: 935293:PL78_RS07185
uniprot id: A0A3S6EYZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

935293:PL78 RS14060
gene id: 935293:PL78_RS14060
uniprot id: A0A3S6F2R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecM family.
messages: Periplasm
messages: Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation.
messages: cytosol

935293:PL78 RS18380
gene id: 935293:PL78_RS18380
uniprot id: A0A3S6F510
names: Subcellular Location Annotation
messages: Cytoplasm

935293:PL78 RS13035
gene id: 935293:PL78_RS13035
uniprot id: A0A3S6F2D7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

935293:PL78 RS18625
gene id: 935293:PL78_RS18625
uniprot id: A0A3S6F560
names: Similarity
messages: Belongs to the UPF0053 family.

935293:PL78 RS07530
gene id: 935293:PL78_RS07530
uniprot id: A0A3S6EYW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family.
messages: Cell inner membrane
messages: Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA).
messages: Membrane
messages: Probably part of a complex composed of WzxE, WzyE and WzzE.

935293:PL78 RS16240
gene id: 935293:PL78_RS16240
uniprot id: A0A3S6F3V8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS00335
gene id: 935293:PL78_RS00335
uniprot id: A0A3S6EUV0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

935293:PL78 RS13715
gene id: 935293:PL78_RS13715
uniprot id: A0A3S6F2N6
names: Similarity
messages: Belongs to the threonine synthase family.

935293:PL78 RS00120
gene id: 935293:PL78_RS00120
uniprot id: A0A3S6EUZ5
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

935293:PL78 RS12700
gene id: 935293:PL78_RS12700
uniprot id: A0A3S6F278
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS05660
gene id: 935293:PL78_RS05660
uniprot id: A0A3S6EXZ2
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

935293:PL78 RS01700
gene id: 935293:PL78_RS01700
uniprot id: A0A3S6EWR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

935293:PL78 RS11845
gene id: 935293:PL78_RS11845
uniprot id: A0A3S6F1R3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

935293:PL78 RS13445
gene id: 935293:PL78_RS13445
uniprot id: A0A3S6F2I5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

935293:PL78 RS06070
gene id: 935293:PL78_RS06070
uniprot id: A0A3S6EZP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

935293:PL78 RS01320
gene id: 935293:PL78_RS01320
uniprot id: A0A3S6EVP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

935293:PL78 RS07700
gene id: 935293:PL78_RS07700
uniprot id: A0A3S6EYZ2
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

935293:PL78 RS17690
gene id: 935293:PL78_RS17690
uniprot id: A0A3S6F4R4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

935293:PL78 RS02460
gene id: 935293:PL78_RS02460
uniprot id: A0A3S6EW57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

935293:PL78 RS08625
gene id: 935293:PL78_RS08625
uniprot id: A0A3S6EZH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-(hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

935293:PL78 RS15640
gene id: 935293:PL78_RS15640
uniprot id: A0A3S6F3H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ivy family.
messages: Periplasm

935293:PL78 RS11835
gene id: 935293:PL78_RS11835
uniprot id: A0A3S6F1N9
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS02015
gene id: 935293:PL78_RS02015
uniprot id: A0A3S6EW30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Dps family.
messages: Cytoplasm
messages: During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
messages: Homododecamer. The 12 subunits form a hollow sphere into which the mineral iron core of up to 500 Fe(3+) can be deposited.

935293:PL78 RS13860
gene id: 935293:PL78_RS13860
uniprot id: A0A3S6F2M9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

935293:PL78 RS01075
gene id: 935293:PL78_RS01075
uniprot id: A0A3S6EVD0
names: Subcellular Location Annotation
messages: Cytoplasm

935293:PL78 RS05730
gene id: 935293:PL78_RS05730
uniprot id: A0A3S6EY57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

935293:PL78 RS13615
gene id: 935293:PL78_RS13615
uniprot id: A0A3S6F2L5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

935293:PL78 RS13855
gene id: 935293:PL78_RS13855
uniprot id: A0A3S6F2J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

935293:PL78 RS00350
gene id: 935293:PL78_RS00350
uniprot id: A0A3S6EUV6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS04135
gene id: 935293:PL78_RS04135
uniprot id: A0A3S6EX45
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

935293:PL78 RS04455
gene id: 935293:PL78_RS04455
uniprot id: A0A3S6EX91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

935293:PL78 RS07940
gene id: 935293:PL78_RS07940
uniprot id: A0A3S6EZD1
names: Subcellular Location Annotation
messages: Cell inner membrane

935293:PL78 RS07035
gene id: 935293:PL78_RS07035
uniprot id: A0A3S6EYV4
names: Function
names: Similarity
names: Subunit
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).
messages: In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
messages: Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.

935293:PL78 RS14720
gene id: 935293:PL78_RS14720
uniprot id: A0A3S6F314
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

935293:PL78 RS04535
gene id: 935293:PL78_RS04535
uniprot id: A0A3S6EXB2
names: Similarity
messages: Belongs to the RutC family.

935293:PL78 RS17550
gene id: 935293:PL78_RS17550
uniprot id: A0A3S6F4H2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhD family.
messages: Cytoplasm
messages: Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.
messages: The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA.

935293:PL78 RS11205
gene id: 935293:PL78_RS11205
uniprot id: A0A3S6F0W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

935293:PL78 RS08200
gene id: 935293:PL78_RS08200
uniprot id: A0A3S6EZ89
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

935293:PL78 RS11685
gene id: 935293:PL78_RS11685
uniprot id: A0A3S6F1L1
names: Similarity
messages: Belongs to the HSP15 family.

935293:PL78 RS09735
gene id: 935293:PL78_RS09735
uniprot id: A0A3S6F168
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EntS (TC 2.A.1.38) family.
messages: Cell inner membrane
messages: Component of an export pathway for enterobactin.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

935293:PL78 RS09925
gene id: 935293:PL78_RS09925
uniprot id: A0A3S6F0A6
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

935293:PL78 RS00575
gene id: 935293:PL78_RS00575
uniprot id: A0A3S6EV20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS16170
gene id: 935293:PL78_RS16170
uniprot id: A0A3S6F3M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

935293:PL78 RS04840
gene id: 935293:PL78_RS04840
uniprot id: A0A3S6EZ33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS13720
gene id: 935293:PL78_RS13720
uniprot id: A0A3S6F2B3
names: Similarity
messages: Belongs to the UPF0246 family.

935293:PL78 RS16955
gene id: 935293:PL78_RS16955
uniprot id: A0A3S6F4G7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

935293:PL78 RS15770
gene id: 935293:PL78_RS15770
uniprot id: A0A3S6F3H3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaA family. HdA subfamily.
messages: Mediates the interaction of DNA replication initiator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinitiation, a process called regulatory inhibition of DnaA or RIDA.
messages: Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA.
messages: The active form seems to be an ADP-bound monomer. Forms the RIDA complex (regulatory inactivation of DnaA) of ATP-DnaA, ADP-Hda and the DNA-loaded beta sliding clamp (dnaN).

935293:PL78 RS12770
gene id: 935293:PL78_RS12770
uniprot id: A0A3S6F218
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

935293:PL78 RS06865
gene id: 935293:PL78_RS06865
uniprot id: A0A3S6EYK2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

935293:PL78 RS00455
gene id: 935293:PL78_RS00455
uniprot id: A0A3S6EUX6
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

935293:PL78 RS01595
gene id: 935293:PL78_RS01595
uniprot id: A0A3S6EVM8
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS04815
gene id: 935293:PL78_RS04815
uniprot id: A0A3S6EXG1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RssB family.
messages: Binds to RpoS.
messages: Phosphorylated. Phosphorylation stimulates the interaction with RpoS and, therefore, the proteolysis of RpoS.
messages: Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co-degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation.

935293:PL78 RS09110
gene id: 935293:PL78_RS09110
uniprot id: A0A3S6EZR4
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

935293:PL78 RS16550
gene id: 935293:PL78_RS16550
uniprot id: A0A3S6F439
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedD family.
messages: Cell inner membrane
messages: Non-essential cell division protein that could be required for efficient cell constriction.
messages: The SPOR domain binds septal peptidoglycans and is required to target DedD to the septal ring.

935293:PL78 RS05240
gene id: 935293:PL78_RS05240
uniprot id: A0A3S6EY12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tus family.
messages: Cytoplasm
messages: Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence.

935293:PL78 RS18905
gene id: 935293:PL78_RS18905
uniprot id: A0A3S6F565
names: Similarity
messages: Belongs to the peptidase S41A family.

935293:PL78 RS02330
gene id: 935293:PL78_RS02330
uniprot id: A0A3S6EWG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

935293:PL78 RS02655
gene id: 935293:PL78_RS02655
uniprot id: A0A3S6EXA8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

935293:PL78 RS07785
gene id: 935293:PL78_RS07785
uniprot id: A0A3S6EZ46
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

935293:PL78 RS03135
gene id: 935293:PL78_RS03135
uniprot id: A0A3S6EWX5
names: Similarity
messages: Belongs to the fabD family.

935293:PL78 RS02555
gene id: 935293:PL78_RS02555
uniprot id: A0A3S6EX88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

935293:PL78 RS16570
gene id: 935293:PL78_RS16570
uniprot id: A0A3S6F5H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

935293:PL78 RS18560
gene id: 935293:PL78_RS18560
uniprot id: A0A3S6F542
names: Subcellular Location Annotation
messages: Cytoplasm

935293:PL78 RS08670
gene id: 935293:PL78_RS08670
uniprot id: A0A3S6EZY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

935293:PL78 RS05770
gene id: 935293:PL78_RS05770
uniprot id: A0A3S6EZ26
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. DtpA subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton-dependent permease that transports di- and tripeptides.

935293:PL78 RS18385
gene id: 935293:PL78_RS18385
uniprot id: A0A3S6F635
names: Subcellular Location Annotation
messages: Cytoplasm

935293:PL78 RS04105
gene id: 935293:PL78_RS04105
uniprot id: A0A3S6EXI5
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS08085
gene id: 935293:PL78_RS08085
uniprot id: A0A3S6EZA8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS15215
gene id: 935293:PL78_RS15215
uniprot id: A0A3S6F359
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS11460
gene id: 935293:PL78_RS11460
uniprot id: A0A3S6F146
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

935293:PL78 RS03300
gene id: 935293:PL78_RS03300
uniprot id: A0A3S6EWM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

935293:PL78 RS04410
gene id: 935293:PL78_RS04410
uniprot id: A0A3S6EX86
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

935293:PL78 RS16925
gene id: 935293:PL78_RS16925
uniprot id: A0A3S6F430
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RcsB family.
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.
messages: Interacts with RcsD.
messages: Phosphorylated and activated by RcsD.

935293:PL78 RS17200
gene id: 935293:PL78_RS17200
uniprot id: A0A3S6F5C2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

935293:PL78 RS07710
gene id: 935293:PL78_RS07710
uniprot id: A0A3S6F0J9
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

935293:PL78 RS17620
gene id: 935293:PL78_RS17620
uniprot id: A0A3S6F4J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

935293:PL78 RS00485
gene id: 935293:PL78_RS00485
uniprot id: A0A3S6EUY6
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

935293:PL78 RS15580
gene id: 935293:PL78_RS15580
uniprot id: A0A3S6F3C0
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

935293:PL78 RS12825
gene id: 935293:PL78_RS12825
uniprot id: A0A3S6F272
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

935293:PL78 RS08655
gene id: 935293:PL78_RS08655
uniprot id: A0A3S6F0L5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Homodimer.

935293:PL78 RS01390
gene id: 935293:PL78_RS01390
uniprot id: A0A3S6EX66
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

935293:PL78 RS13010
gene id: 935293:PL78_RS13010
uniprot id: A0A3S6F309
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

935293:PL78 RS18965
gene id: 935293:PL78_RS18965
uniprot id: A0A3S6F5C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

935293:PL78 RS01170
gene id: 935293:PL78_RS01170
uniprot id: A0A3S6EVD5
names: Function
names: Similarity
messages: Belongs to the IUNH family. RihA subfamily.
messages: Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively.

935293:PL78 RS18570
gene id: 935293:PL78_RS18570
uniprot id: A0A3S6F672
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

935293:PL78 RS03240
gene id: 935293:PL78_RS03240
uniprot id: A0A3S6EY76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

935293:PL78 RS12960
gene id: 935293:PL78_RS12960
uniprot id: A0A3S6F2Z9
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS11255
gene id: 935293:PL78_RS11255
uniprot id: A0A3S6F0X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

935293:PL78 RS18655
gene id: 935293:PL78_RS18655
uniprot id: A0A3S6F516
names: Similarity
messages: Belongs to the UPF0181 family.

935293:PL78 RS08880
gene id: 935293:PL78_RS08880
uniprot id: A0A3S6EZX7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family.
messages: Catalyzes the facilitated diffusion of 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) into the cell.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS11240
gene id: 935293:PL78_RS11240
uniprot id: A0A3S6F0Y5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

935293:PL78 RS12000
gene id: 935293:PL78_RS12000
uniprot id: A0A3S6F1D3
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

935293:PL78 RS17765
gene id: 935293:PL78_RS17765
uniprot id: A0A3S6F4J1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

935293:PL78 RS12900
gene id: 935293:PL78_RS12900
uniprot id: A0A3S6F1X0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

935293:PL78 RS02070
gene id: 935293:PL78_RS02070
uniprot id: A0A3S6EWD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

935293:PL78 RS03635
gene id: 935293:PL78_RS03635
uniprot id: A0A3S6EWT3
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

935293:PL78 RS00530
gene id: 935293:PL78_RS00530
uniprot id: A0A3S6EVI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS17100
gene id: 935293:PL78_RS17100
uniprot id: A0A3S6F4B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

935293:PL78 RS02080
gene id: 935293:PL78_RS02080
uniprot id: A0A3S6EWB5
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS10250
gene id: 935293:PL78_RS10250
uniprot id: A0A3S6F0E7
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

935293:PL78 RS13060
gene id: 935293:PL78_RS13060
uniprot id: A0A3S6F323
names: Similarity
messages: Belongs to the peptidase S13 family.

935293:PL78 RS02355
gene id: 935293:PL78_RS02355
uniprot id: A0A3S6EX49
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

935293:PL78 RS15935
gene id: 935293:PL78_RS15935
uniprot id: A0A3S6F3I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

935293:PL78 RS01415
gene id: 935293:PL78_RS01415
uniprot id: A0A3S6EVJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

935293:PL78 RS02115
gene id: 935293:PL78_RS02115
uniprot id: A0A3S6EW49
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS00500
gene id: 935293:PL78_RS00500
uniprot id: A0A3S6EUZ0
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. Cof family.
messages: Catalyzes the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate (HMP-P).

935293:PL78 RS07825
gene id: 935293:PL78_RS07825
uniprot id: A0A3S6EZ41
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MetJ family.
messages: Cytoplasm
messages: Does not bind DNA by a helix-turn-helix motif.
messages: Homodimer.
messages: This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.

935293:PL78 RS09145
gene id: 935293:PL78_RS09145
uniprot id: A0A3S6F070
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

935293:PL78 RS08855
gene id: 935293:PL78_RS08855
uniprot id: A0A3S6EZL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

935293:PL78 RS12790
gene id: 935293:PL78_RS12790
uniprot id: A0A3S6F3F0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

935293:PL78 RS14895
gene id: 935293:PL78_RS14895
uniprot id: A0A3S6F345
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS12780
gene id: 935293:PL78_RS12780
uniprot id: A0A3S6F1T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

935293:PL78 RS03165
gene id: 935293:PL78_RS03165
uniprot id: A0A3S6EWJ5
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

935293:PL78 RS10990
gene id: 935293:PL78_RS10990
uniprot id: A0A3S6F0Y4
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

935293:PL78 RS11435
gene id: 935293:PL78_RS11435
uniprot id: A0A3S6F1G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
messages: Cell inner membrane
messages: Interacts with the regulatory subunit KefG.
messages: Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.

935293:PL78 RS02850
gene id: 935293:PL78_RS02850
uniprot id: A0A3S6EWE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MatP family.
messages: Cytoplasm
messages: Homodimer.
messages: Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.

935293:PL78 RS10830
gene id: 935293:PL78_RS10830
uniprot id: A0A3S6F0U4
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS09945
gene id: 935293:PL78_RS09945
uniprot id: A0A3S6F0N3
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

935293:PL78 RS05550
gene id: 935293:PL78_RS05550
uniprot id: A0A3S6EZG5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Asr family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Periplasm
messages: Proteolytic processing gives rise to the active protein.
messages: Required for growth and/or survival at acidic conditions.

935293:PL78 RS08885
gene id: 935293:PL78_RS08885
uniprot id: A0A3S6F024
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.
messages: In the N-terminal section; belongs to the 2-acyl-GPE acetyltransferase family.
messages: Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1.

935293:PL78 RS11280
gene id: 935293:PL78_RS11280
uniprot id: A0A3S6F182
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

935293:PL78 RS17790
gene id: 935293:PL78_RS17790
uniprot id: A0A3S6F4T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FliT family.
messages: Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD. As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus.
messages: Homodimer. Interacts with FliD and FlhC.
messages: cytosol

935293:PL78 RS11195
gene id: 935293:PL78_RS11195
uniprot id: A0A3S6F1C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

935293:PL78 RS01080
gene id: 935293:PL78_RS01080
uniprot id: A0A3S6EWG2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

935293:PL78 RS16035
gene id: 935293:PL78_RS16035
uniprot id: A0A3S6F3K6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

935293:PL78 RS10180
gene id: 935293:PL78_RS10180
uniprot id: A0A3S6F1G2
names: Function
names: Similarity
messages: Belongs to the phage GPA family.
messages: Possible endonuclease which induces a single-strand cut and initiates DNA replication.

935293:PL78 RS05285
gene id: 935293:PL78_RS05285
uniprot id: A0A3S6EXQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

935293:PL78 RS01125
gene id: 935293:PL78_RS01125
uniprot id: A0A3S6EVE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

935293:PL78 RS00855
gene id: 935293:PL78_RS00855
uniprot id: A0A3S6EWW4
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

935293:PL78 RS12370
gene id: 935293:PL78_RS12370
uniprot id: A0A3S6F1Q0
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS02950
gene id: 935293:PL78_RS02950
uniprot id: A0A3S6EWF3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS16075
gene id: 935293:PL78_RS16075
uniprot id: A0A3S6F419
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

935293:PL78 RS03655
gene id: 935293:PL78_RS03655
uniprot id: A0A3S6EWV0
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

935293:PL78 RS09480
gene id: 935293:PL78_RS09480
uniprot id: A0A3S6F120
names: Similarity
messages: Belongs to the GSP E family.

935293:PL78 RS05405
gene id: 935293:PL78_RS05405
uniprot id: A0A3S6EXS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

935293:PL78 RS15970
gene id: 935293:PL78_RS15970
uniprot id: A0A3S6F3L7
names: Similarity
messages: Belongs to the DapA family.

935293:PL78 RS14245
gene id: 935293:PL78_RS14245
uniprot id: A0A3S6F2R0
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

935293:PL78 RS05250
gene id: 935293:PL78_RS05250
uniprot id: A0A3S6EXP8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS07335
gene id: 935293:PL78_RS07335
uniprot id: A0A3S6EZ21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

935293:PL78 RS17650
gene id: 935293:PL78_RS17650
uniprot id: A0A3S6F4J2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

935293:PL78 RS05265
gene id: 935293:PL78_RS05265
uniprot id: A0A3S6EYS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.

935293:PL78 RS06135
gene id: 935293:PL78_RS06135
uniprot id: A0A3S6EY86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Cell membrane

935293:PL78 RS10985
gene id: 935293:PL78_RS10985
uniprot id: A0A3S6F1X1
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

935293:PL78 RS04630
gene id: 935293:PL78_RS04630
uniprot id: A0A3S6EYZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

935293:PL78 RS10425
gene id: 935293:PL78_RS10425
uniprot id: A0A3S6F0K9
names: Similarity
messages: Belongs to the glutamate synthase family.

935293:PL78 RS03120
gene id: 935293:PL78_RS03120
uniprot id: A0A3S6EWP7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

935293:PL78 RS15940
gene id: 935293:PL78_RS15940
uniprot id: A0A3S6F3N1
names: Similarity
messages: Belongs to the UPF0178 family.

935293:PL78 RS00750
gene id: 935293:PL78_RS00750
uniprot id: A0A3S6EVK8
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

935293:PL78 RS17730
gene id: 935293:PL78_RS17730
uniprot id: A0A3S6F5M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

935293:PL78 RS00420
gene id: 935293:PL78_RS00420
uniprot id: A0A3S6EUY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

935293:PL78 RS11945
gene id: 935293:PL78_RS11945
uniprot id: A0A3S6F303
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

935293:PL78 RS01155
gene id: 935293:PL78_RS01155
uniprot id: A0A3S6EVU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

935293:PL78 RS02715
gene id: 935293:PL78_RS02715
uniprot id: A0A3S6EWH0
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
messages: Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.

935293:PL78 RS16390
gene id: 935293:PL78_RS16390
uniprot id: A0A3S6F4U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

935293:PL78 RS16045
gene id: 935293:PL78_RS16045
uniprot id: A0A3S6F3Q4
names: Subcellular Location Annotation
messages: Cell inner membrane

935293:PL78 RS04700
gene id: 935293:PL78_RS04700
uniprot id: A0A3S6EYG5
names: Similarity
messages: Belongs to the TPP enzyme family.

935293:PL78 RS07890
gene id: 935293:PL78_RS07890
uniprot id: A0A3S6EZC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS07415
gene id: 935293:PL78_RS07415
uniprot id: A0A3S6EYW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

935293:PL78 RS08525
gene id: 935293:PL78_RS08525
uniprot id: A0A3S6EZE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RcsF family.
messages: Cell outer membrane
messages: Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects.

935293:PL78 RS07610
gene id: 935293:PL78_RS07610
uniprot id: A0A3S6EZE9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS17705
gene id: 935293:PL78_RS17705
uniprot id: A0A3S6F4Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

935293:PL78 RS07885
gene id: 935293:PL78_RS07885
uniprot id: A0A3S6EZ67
names: Similarity
messages: Belongs to the FBPase class 2 family.

935293:PL78 RS03140
gene id: 935293:PL78_RS03140
uniprot id: A0A3S6EY54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

935293:PL78 RS05885
gene id: 935293:PL78_RS05885
uniprot id: A0A3S6EYI1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

935293:PL78 RS18980
gene id: 935293:PL78_RS18980
uniprot id: A0A3S6F5F9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

935293:PL78 RS14075
gene id: 935293:PL78_RS14075
uniprot id: A0A3S6F2Y0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

935293:PL78 RS17560
gene id: 935293:PL78_RS17560
uniprot id: A0A3S6F647
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

935293:PL78 RS05935
gene id: 935293:PL78_RS05935
uniprot id: A0A3S6EYJ0
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

935293:PL78 RS06850
gene id: 935293:PL78_RS06850
uniprot id: A0A3S6EYI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

935293:PL78 RS00865
gene id: 935293:PL78_RS00865
uniprot id: A0A3S6EV71
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

935293:PL78 RS14610
gene id: 935293:PL78_RS14610
uniprot id: A0A3S6F352
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane

935293:PL78 RS12955
gene id: 935293:PL78_RS12955
uniprot id: A0A3S6F213
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

935293:PL78 RS07475
gene id: 935293:PL78_RS07475
uniprot id: A0A3S6EZZ3
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

935293:PL78 RS08825
gene id: 935293:PL78_RS08825
uniprot id: A0A3S6EZP9
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS08595
gene id: 935293:PL78_RS08595
uniprot id: A0A3S6EZJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

935293:PL78 RS00625
gene id: 935293:PL78_RS00625
uniprot id: A0A3S6EW76
names: Subcellular Location Annotation
messages: Cell inner membrane

935293:PL78 RS01640
gene id: 935293:PL78_RS01640
uniprot id: A0A3S6EVM4
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

935293:PL78 RS11810
gene id: 935293:PL78_RS11810
uniprot id: A0A3S6F1B4
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

935293:PL78 RS02140
gene id: 935293:PL78_RS02140
uniprot id: A0A3S6EVY1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

935293:PL78 RS03915
gene id: 935293:PL78_RS03915
uniprot id: A0A3S6EYK3
names: Subcellular Location Annotation
messages: Cytoplasm

935293:PL78 RS07855
gene id: 935293:PL78_RS07855
uniprot id: A0A3S6EZF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

935293:PL78 RS16250
gene id: 935293:PL78_RS16250
uniprot id: A0A3S6F422
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family. DsdA subfamily.
messages: Monomer.

935293:PL78 RS13750
gene id: 935293:PL78_RS13750
uniprot id: A0A3S6F3F1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

935293:PL78 RS08695
gene id: 935293:PL78_RS08695
uniprot id: A0A3S6EZK9
names: Similarity
messages: Belongs to the UPF0325 family.

935293:PL78 RS05635
gene id: 935293:PL78_RS05635
uniprot id: A0A3S6EYD2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

935293:PL78 RS10815
gene id: 935293:PL78_RS10815
uniprot id: A0A3S6F2D0
names: Function
names: Similarity
names: Subunit
messages: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.
messages: Belongs to the transcriptional regulatory Fis family.
messages: Homodimer.

935293:PL78 RS05430
gene id: 935293:PL78_RS05430
uniprot id: A0A3S6EXZ6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

935293:PL78 RS01655
gene id: 935293:PL78_RS01655
uniprot id: A0A3S6EVN5
names: Similarity
messages: Belongs to the ModE family.

935293:PL78 RS04955
gene id: 935293:PL78_RS04955
uniprot id: A0A3S6EXI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

935293:PL78 RS12550
gene id: 935293:PL78_RS12550
uniprot id: A0A3S6F247
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

935293:PL78 RS13170
gene id: 935293:PL78_RS13170
uniprot id: A0A3S6F254
names: Similarity
messages: Belongs to the UPF0597 family.

935293:PL78 RS10980
gene id: 935293:PL78_RS10980
uniprot id: A0A3S6F0X1
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

935293:PL78 RS14100
gene id: 935293:PL78_RS14100
uniprot id: A0A3S6F3M3
names: Similarity
messages: Belongs to the GSP E family.

935293:PL78 RS16880
gene id: 935293:PL78_RS16880
uniprot id: A0A3S6F457
names: Similarity
messages: Belongs to the CinA family.

935293:PL78 RS13985
gene id: 935293:PL78_RS13985
uniprot id: A0A3S6F2G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

935293:PL78 RS11610
gene id: 935293:PL78_RS11610
uniprot id: A0A3S6F176
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Monomer.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

935293:PL78 RS18615
gene id: 935293:PL78_RS18615
uniprot id: A0A3S6F556
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS12920
gene id: 935293:PL78_RS12920
uniprot id: A0A3S6F248
names: Subcellular Location Annotation
messages: Cytoplasm

935293:PL78 RS08775
gene id: 935293:PL78_RS08775
uniprot id: A0A3S6EZK4
names: Function
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.

935293:PL78 RS14270
gene id: 935293:PL78_RS14270
uniprot id: A0A3S6F2L7
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

935293:PL78 RS00595
gene id: 935293:PL78_RS00595
uniprot id: A0A3S6EVH7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

935293:PL78 RS01095
gene id: 935293:PL78_RS01095
uniprot id: A0A3S6EVU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TatA/E family. TatE subfamily.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA.

935293:PL78 RS15365
gene id: 935293:PL78_RS15365
uniprot id: A0A3S6F388
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

935293:PL78 RS07255
gene id: 935293:PL78_RS07255
uniprot id: A0A3S6F0B4
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

935293:PL78 RS00460
gene id: 935293:PL78_RS00460
uniprot id: A0A3S6EUY5
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

935293:PL78 RS06455
gene id: 935293:PL78_RS06455
uniprot id: A0A3S6EYF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

935293:PL78 RS17565
gene id: 935293:PL78_RS17565
uniprot id: A0A3S6F4F2
names: Similarity
messages: Belongs to the MotB family.

935293:PL78 RS15200
gene id: 935293:PL78_RS15200
uniprot id: A0A3S6F3A2
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

935293:PL78 RS16155
gene id: 935293:PL78_RS16155
uniprot id: A0A3S6F3P8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

935293:PL78 RS14470
gene id: 935293:PL78_RS14470
uniprot id: A0A3S6F366
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Homodimer.

935293:PL78 RS02570
gene id: 935293:PL78_RS02570
uniprot id: A0A3S6EWN5
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS12210
gene id: 935293:PL78_RS12210
uniprot id: A0A3S6F1H4
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS17220
gene id: 935293:PL78_RS17220
uniprot id: A0A3S6F4B3
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS16150
gene id: 935293:PL78_RS16150
uniprot id: A0A3S6F3Z8
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

935293:PL78 RS01905
gene id: 935293:PL78_RS01905
uniprot id: A0A3S6EVU3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

935293:PL78 RS10835
gene id: 935293:PL78_RS10835
uniprot id: A0A3S6F1T9
names: Subcellular Location Annotation
messages: Membrane

935293:PL78 RS09975
gene id: 935293:PL78_RS09975
uniprot id: A0A3S6F0C6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
messages: Homooctamer.