93378:I6G97 RS09300
gene id: 93378:I6G97_RS09300
uniprot id: A0A376DHX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

93378:I6G97 RS02015
gene id: 93378:I6G97_RS02015
uniprot id: A0A376D6A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

93378:I6G97 RS13755
gene id: 93378:I6G97_RS13755
uniprot id: A0A376DDT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

93378:I6G97 RS03670
gene id: 93378:I6G97_RS03670
uniprot id: A0A376DN86
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M20A family. ArgE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids. Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.
messages: Cytoplasm
messages: Homodimer.

93378:I6G97 RS15550
gene id: 93378:I6G97_RS15550
uniprot id: A0A376DA85
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93378:I6G97 RS16245
gene id: 93378:I6G97_RS16245
uniprot id: A0A376DA76
names: Similarity
messages: Belongs to the UPF0250 family.

93378:I6G97 RS10740
gene id: 93378:I6G97_RS10740
uniprot id: A0A376DG94
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

93378:I6G97 RS14860
gene id: 93378:I6G97_RS14860
uniprot id: A0A376DCR9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

93378:I6G97 RS12465
gene id: 93378:I6G97_RS12465
uniprot id: A0A376DEJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: Membrane

93378:I6G97 RS02860
gene id: 93378:I6G97_RS02860
uniprot id: A0A376D532
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

93378:I6G97 RS03150
gene id: 93378:I6G97_RS03150
uniprot id: A0A376D5L4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

93378:I6G97 RS00400
gene id: 93378:I6G97_RS00400
uniprot id: A0A376D884
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93378:I6G97 RS12565
gene id: 93378:I6G97_RS12565
uniprot id: A0A376DEA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ProQ family.
messages: Cytoplasm
messages: RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism.

93378:I6G97 RS02455
gene id: 93378:I6G97_RS02455
uniprot id: A0A376D637
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

93378:I6G97 RS06745
gene id: 93378:I6G97_RS06745
uniprot id: A0A376DKN0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

93378:I6G97 RS06445
gene id: 93378:I6G97_RS06445
uniprot id: A0A376DKR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

93378:I6G97 RS10820
gene id: 93378:I6G97_RS10820
uniprot id: A0A376DGX8
names: Similarity
messages: Belongs to the universal stress protein A family.

93378:I6G97 RS13870
gene id: 93378:I6G97_RS13870
uniprot id: A0A376DDX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

93378:I6G97 RS04040
gene id: 93378:I6G97_RS04040
uniprot id: A0A376DMS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family.
messages: Cell inner membrane
messages: Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA).
messages: Membrane
messages: Probably part of a complex composed of WzxE, WzyE and WzzE.

93378:I6G97 RS14655
gene id: 93378:I6G97_RS14655
uniprot id: A0A376DBS6
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: To H.influenzae HI_0842.

93378:I6G97 RS06510
gene id: 93378:I6G97_RS06510
uniprot id: A0A376DLT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

93378:I6G97 RS11920
gene id: 93378:I6G97_RS11920
uniprot id: A0A376DFT6
names: Similarity
messages: Belongs to the peptidase C40 family.

93378:I6G97 RS13740
gene id: 93378:I6G97_RS13740
uniprot id: A0A376DD41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

93378:I6G97 RS06715
gene id: 93378:I6G97_RS06715
uniprot id: A0A376DKN9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane
messages: The complex is composed of two ATP-binding proteins (ThiQ), two transmembrane proteins (ThiP) and a solute-binding protein (ThiB).

93378:I6G97 RS13400
gene id: 93378:I6G97_RS13400
uniprot id: A0A376DDG9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS17220
gene id: 93378:I6G97_RS17220
uniprot id: A0A376D9H8
names: Function
names: Subunit
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.
messages: The DNA polymerase holoenzyme is a complex that contains 10 different types of subunits. These subunits are organized into 3 functionally essential subassemblies: the pol III core, the beta sliding clamp processivity factor and the clamp-loading complex. The pol III core (subunits alpha,epsilon and theta) contains the polymerase and the 3'-5' exonuclease proofreading activities. The polymerase is tethered to the template via the sliding clamp processivity factor. The clamp-loading complex assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork. This complex contains delta, delta', psi and chi, and copies of either or both of two different DnaX proteins, gamma and tau.

93378:I6G97 RS14595
gene id: 93378:I6G97_RS14595
uniprot id: A0A376DBM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

93378:I6G97 RS01740
gene id: 93378:I6G97_RS01740
uniprot id: A0A376D8T2
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

93378:I6G97 RS04310
gene id: 93378:I6G97_RS04310
uniprot id: A0A376DNN8
names: Similarity
messages: Belongs to the IMPACT family.

93378:I6G97 RS13535
gene id: 93378:I6G97_RS13535
uniprot id: A0A376DCS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

93378:I6G97 RS10515
gene id: 93378:I6G97_RS10515
uniprot id: A0A376DH85
names: Similarity
messages: Belongs to the UPF0162 family.

93378:I6G97 RS04580
gene id: 93378:I6G97_RS04580
uniprot id: A0A376DMJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MalK), two transmembrane proteins (MalG and MalF) and a solute-binding protein (MalE).

93378:I6G97 RS06015
gene id: 93378:I6G97_RS06015
uniprot id: A0A376DL84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

93378:I6G97 RS00355
gene id: 93378:I6G97_RS00355
uniprot id: A0A376D940
names: Function
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

93378:I6G97 RS07640
gene id: 93378:I6G97_RS07640
uniprot id: A0A376DJI3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

93378:I6G97 RS14505
gene id: 93378:I6G97_RS14505
uniprot id: A0A376DE05
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TorC/TorY family.
messages: Binds 5 heme groups per subunit.
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS17035
gene id: 93378:I6G97_RS17035
uniprot id: A0A376DA21
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

93378:I6G97 RS08550
gene id: 93378:I6G97_RS08550
uniprot id: A0A376DID4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93378:I6G97 RS09545
gene id: 93378:I6G97_RS09545
uniprot id: A0A376DHM7
names: Similarity
messages: Belongs to the UPF0319 family.

93378:I6G97 RS03630
gene id: 93378:I6G97_RS03630
uniprot id: A0A376DN59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

93378:I6G97 RS16785
gene id: 93378:I6G97_RS16785
uniprot id: A0A376D9L1
names: Similarity
messages: Belongs to the Dps family.

93378:I6G97 RS02260
gene id: 93378:I6G97_RS02260
uniprot id: A0A376D5R6
names: Subcellular Location Annotation
messages: Cell inner membrane

93378:I6G97 RS01115
gene id: 93378:I6G97_RS01115
uniprot id: A0A376D8J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS12020
gene id: 93378:I6G97_RS12020
uniprot id: A0A376DF02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

93378:I6G97 RS03815
gene id: 93378:I6G97_RS03815
uniprot id: A0A376DN04
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

93378:I6G97 RS04220
gene id: 93378:I6G97_RS04220
uniprot id: A0A376DMQ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

93378:I6G97 RS13845
gene id: 93378:I6G97_RS13845
uniprot id: A0A376DCT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS14975
gene id: 93378:I6G97_RS14975
uniprot id: A0A376DC60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

93378:I6G97 RS12400
gene id: 93378:I6G97_RS12400
uniprot id: A0A376DEJ9
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.
messages: Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters.

93378:I6G97 RS00430
gene id: 93378:I6G97_RS00430
uniprot id: A0A376DAB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family. LpxP subfamily.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(acyl)-lipid IV(A).
messages: Cell inner membrane

93378:I6G97 RS16315
gene id: 93378:I6G97_RS16315
uniprot id: A0A376D9F2
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS16630
gene id: 93378:I6G97_RS16630
uniprot id: A0A376D9J3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

93378:I6G97 RS01140
gene id: 93378:I6G97_RS01140
uniprot id: A0A376D8I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

93378:I6G97 RS04055
gene id: 93378:I6G97_RS04055
uniprot id: A0A376DMU6
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family.
messages: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis.

93378:I6G97 RS13135
gene id: 93378:I6G97_RS13135
uniprot id: A0A376DFM3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

93378:I6G97 RS03805
gene id: 93378:I6G97_RS03805
uniprot id: A0A376DMS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

93378:I6G97 RS00915
gene id: 93378:I6G97_RS00915
uniprot id: A0A376D788
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

93378:I6G97 RS16170
gene id: 93378:I6G97_RS16170
uniprot id: A0A376D9J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

93378:I6G97 RS15080
gene id: 93378:I6G97_RS15080
uniprot id: A0A376DBW4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

93378:I6G97 RS02750
gene id: 93378:I6G97_RS02750
uniprot id: A0A376D632
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

93378:I6G97 RS15135
gene id: 93378:I6G97_RS15135
uniprot id: A0A376DC88
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS07430
gene id: 93378:I6G97_RS07430
uniprot id: A0A376DJR7
names: Similarity
messages: Belongs to the UPF0253 family.

93378:I6G97 RS02160
gene id: 93378:I6G97_RS02160
uniprot id: A0A376D631
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

93378:I6G97 RS14985
gene id: 93378:I6G97_RS14985
uniprot id: A0A376DCK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

93378:I6G97 RS03665
gene id: 93378:I6G97_RS03665
uniprot id: A0A376DMW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

93378:I6G97 RS08155
gene id: 93378:I6G97_RS08155
uniprot id: A0A376DJP6
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS16955
gene id: 93378:I6G97_RS16955
uniprot id: A0A376D9S2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

93378:I6G97 RS01605
gene id: 93378:I6G97_RS01605
uniprot id: A0A376D8X6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

93378:I6G97 RS13745
gene id: 93378:I6G97_RS13745
uniprot id: A0A376DCW9
names: Similarity
messages: Belongs to the fabD family.

93378:I6G97 RS06280
gene id: 93378:I6G97_RS06280
uniprot id: A0A376DKY9
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS06630
gene id: 93378:I6G97_RS06630
uniprot id: A0A376DKJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

93378:I6G97 RS16295
gene id: 93378:I6G97_RS16295
uniprot id: A0A376DAK9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

93378:I6G97 RS11770
gene id: 93378:I6G97_RS11770
uniprot id: A0A376DGB5
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

93378:I6G97 RS05520
gene id: 93378:I6G97_RS05520
uniprot id: A0A376DMQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

93378:I6G97 RS01935
gene id: 93378:I6G97_RS01935
uniprot id: A0A376D700
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

93378:I6G97 RS16875
gene id: 93378:I6G97_RS16875
uniprot id: A0A376DB71
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

93378:I6G97 RS02395
gene id: 93378:I6G97_RS02395
uniprot id: A0A376D6K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GlpE family.
messages: Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
messages: Cytoplasm

93378:I6G97 RS14230
gene id: 93378:I6G97_RS14230
uniprot id: A0A376DC02
names: Similarity
messages: Belongs to the peptidase A24 family.

93378:I6G97 RS14345
gene id: 93378:I6G97_RS14345
uniprot id: A0A376DC89
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.

93378:I6G97 RS09590
gene id: 93378:I6G97_RS09590
uniprot id: A0A376DIJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
messages: Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Homodimer.

93378:I6G97 RS01295
gene id: 93378:I6G97_RS01295
uniprot id: A0A376D7S5
names: Similarity
messages: Belongs to the HsdR family.

93378:I6G97 RS11790
gene id: 93378:I6G97_RS11790
uniprot id: A0A376DFA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

93378:I6G97 RS16640
gene id: 93378:I6G97_RS16640
uniprot id: A0A376D9D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

93378:I6G97 RS08380
gene id: 93378:I6G97_RS08380
uniprot id: A0A376DIU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

93378:I6G97 RS02965
gene id: 93378:I6G97_RS02965
uniprot id: A0A376D5G9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MetJ family.
messages: Cytoplasm
messages: Does not bind DNA by a helix-turn-helix motif.
messages: Homodimer.
messages: This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.

93378:I6G97 RS08815
gene id: 93378:I6G97_RS08815
uniprot id: A0A376DJI8
names: Subunit
messages: Homodimer.

93378:I6G97 RS04470
gene id: 93378:I6G97_RS04470
uniprot id: A0A376DNJ9
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

93378:I6G97 RS11625
gene id: 93378:I6G97_RS11625
uniprot id: A0A376DHG4
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

93378:I6G97 RS06130
gene id: 93378:I6G97_RS06130
uniprot id: A0A376DL63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rnk family.
messages: Interacts with the RNA polymerase.
messages: May act as an anti-Gre factor.

93378:I6G97 RS13210
gene id: 93378:I6G97_RS13210
uniprot id: A0A376DES5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

93378:I6G97 RS04500
gene id: 93378:I6G97_RS04500
uniprot id: A0A376DPI8
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt. Acetylates CheY, the response regulator involved in flagellar movement and chemotaxis.

93378:I6G97 RS01520
gene id: 93378:I6G97_RS01520
uniprot id: A0A376D744
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

93378:I6G97 RS04650
gene id: 93378:I6G97_RS04650
uniprot id: A0A376DPD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.
messages: Represents a citryl-ACP lyase.

93378:I6G97 RS11240
gene id: 93378:I6G97_RS11240
uniprot id: A0A376DH23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

93378:I6G97 RS05405
gene id: 93378:I6G97_RS05405
uniprot id: A0A376DLP4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

93378:I6G97 RS17305
gene id: 93378:I6G97_RS17305
uniprot id: A0A376D9D5
names: Subcellular Location Annotation
messages: Cytoplasm

93378:I6G97 RS16200
gene id: 93378:I6G97_RS16200
uniprot id: A0A376DAN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

93378:I6G97 RS09295
gene id: 93378:I6G97_RS09295
uniprot id: A0A376DJ47
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

93378:I6G97 RS12560
gene id: 93378:I6G97_RS12560
uniprot id: A0A376DEG9
names: Similarity
messages: Belongs to the peptidase S41A family.

93378:I6G97 RS14915
gene id: 93378:I6G97_RS14915
uniprot id: A0A376DBU7
names: Similarity
messages: Belongs to the peptidase A31 family.

93378:I6G97 RS02635
gene id: 93378:I6G97_RS02635
uniprot id: A0A376D6G6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

93378:I6G97 RS09615
gene id: 93378:I6G97_RS09615
uniprot id: A0A376DI40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArnE family.
messages: Cell inner membrane
messages: Heterodimer of ArnE and ArnF.
messages: Membrane
messages: Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.

93378:I6G97 RS04710
gene id: 93378:I6G97_RS04710
uniprot id: A0A376DME6
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

93378:I6G97 RS12495
gene id: 93378:I6G97_RS12495
uniprot id: A0A376DGF7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

93378:I6G97 RS06740
gene id: 93378:I6G97_RS06740
uniprot id: A0A376DKJ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

93378:I6G97 RS14580
gene id: 93378:I6G97_RS14580
uniprot id: A0A376DCV1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport.

93378:I6G97 RS11265
gene id: 93378:I6G97_RS11265
uniprot id: A0A376DGH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0266 family.
messages: Cell membrane
messages: Membrane

93378:I6G97 RS15295
gene id: 93378:I6G97_RS15295
uniprot id: A0A376DAM0
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

93378:I6G97 RS07975
gene id: 93378:I6G97_RS07975
uniprot id: A0A376DJC1
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS04845
gene id: 93378:I6G97_RS04845
uniprot id: A0A376DN74
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

93378:I6G97 RS00165
gene id: 93378:I6G97_RS00165
uniprot id: A0A376IZB7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

93378:I6G97 RS01985
gene id: 93378:I6G97_RS01985
uniprot id: A0A376D617
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

93378:I6G97 RS12645
gene id: 93378:I6G97_RS12645
uniprot id: A0A376DDX7
names: Subcellular Location Annotation
messages: Cell surface

93378:I6G97 RS11440
gene id: 93378:I6G97_RS11440
uniprot id: A0A376DFK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

93378:I6G97 RS00110
gene id: 93378:I6G97_RS00110
uniprot id: A0A376J470
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

93378:I6G97 RS16435
gene id: 93378:I6G97_RS16435
uniprot id: A0A376DAE7
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

93378:I6G97 RS06155
gene id: 93378:I6G97_RS06155
uniprot id: A0A376DL54
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

93378:I6G97 RS08780
gene id: 93378:I6G97_RS08780
uniprot id: A0A376DJJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapF family.
messages: Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

93378:I6G97 RS01930
gene id: 93378:I6G97_RS01930
uniprot id: A0A376D7L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

93378:I6G97 RS07065
gene id: 93378:I6G97_RS07065
uniprot id: A0A376DK43
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

93378:I6G97 RS11270
gene id: 93378:I6G97_RS11270
uniprot id: A0A376DFQ5
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS06560
gene id: 93378:I6G97_RS06560
uniprot id: A0A376DKU6
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

93378:I6G97 RS00235
gene id: 93378:I6G97_RS00235
uniprot id: A0A376IYV3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TraA family.
messages: Cell inner membrane
messages: Membrane
messages: Monomer. Interacts with itself to form filaments; also interacts with TraQ.
messages: Secreted

93378:I6G97 RS06895
gene id: 93378:I6G97_RS06895
uniprot id: A0A376DKH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

93378:I6G97 RS08345
gene id: 93378:I6G97_RS08345
uniprot id: A0A376DKQ4
names: Subcellular Location Annotation
messages: Cell inner membrane

93378:I6G97 RS05425
gene id: 93378:I6G97_RS05425
uniprot id: A0A376DLN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

93378:I6G97 RS02390
gene id: 93378:I6G97_RS02390
uniprot id: A0A376D658
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Cell membrane
messages: Membrane
messages: Rhomboid-type serine protease that catalyzes intramembrane proteolysis.

93378:I6G97 RS04560
gene id: 93378:I6G97_RS04560
uniprot id: A0A376DM28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

93378:I6G97 RS05970
gene id: 93378:I6G97_RS05970
uniprot id: A0A376DLF9
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

93378:I6G97 RS15055
gene id: 93378:I6G97_RS15055
uniprot id: A0A376DBX3
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS11840
gene id: 93378:I6G97_RS11840
uniprot id: A0A376DF83
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

93378:I6G97 RS10380
gene id: 93378:I6G97_RS10380
uniprot id: A0A376DGS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

93378:I6G97 RS07560
gene id: 93378:I6G97_RS07560
uniprot id: A0A376DJQ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

93378:I6G97 RS06370
gene id: 93378:I6G97_RS06370
uniprot id: A0A376DKW9
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

93378:I6G97 RS05550
gene id: 93378:I6G97_RS05550
uniprot id: A0A376DLI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

93378:I6G97 RS13285
gene id: 93378:I6G97_RS13285
uniprot id: A0A376DDJ2
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS03515
gene id: 93378:I6G97_RS03515
uniprot id: A0A376DPS3
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS11705
gene id: 93378:I6G97_RS11705
uniprot id: A0A376DFI9
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

93378:I6G97 RS12915
gene id: 93378:I6G97_RS12915
uniprot id: A0A376DDW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gtrA family.
messages: Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane.
messages: Membrane

93378:I6G97 RS09495
gene id: 93378:I6G97_RS09495
uniprot id: A0A376DHP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

93378:I6G97 RS04715
gene id: 93378:I6G97_RS04715
uniprot id: A0A376DMY1
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

93378:I6G97 RS12610
gene id: 93378:I6G97_RS12610
uniprot id: A0A376DDY5
names: Similarity
messages: Belongs to the UPF0251 family.

93378:I6G97 RS04575
gene id: 93378:I6G97_RS04575
uniprot id: A0A376DMD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93378:I6G97 RS15665
gene id: 93378:I6G97_RS15665
uniprot id: A0A376DAN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS01995
gene id: 93378:I6G97_RS01995
uniprot id: A0A376D778
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

93378:I6G97 RS05335
gene id: 93378:I6G97_RS05335
uniprot id: A0A376DN62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RIC family. YtfE subfamily.
messages: Cytoplasm
messages: Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions.
messages: Homodimer.

93378:I6G97 RS14130
gene id: 93378:I6G97_RS14130
uniprot id: A0A376DCG3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. YcaD (TC 2.A.1.26) family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93378:I6G97 RS10745
gene id: 93378:I6G97_RS10745
uniprot id: A0A376DGE0
names: Similarity
names: Subunit
messages: Belongs to the KHG/KDPG aldolase family.
messages: Homotrimer.

93378:I6G97 RS09255
gene id: 93378:I6G97_RS09255
uniprot id: A0A376DHV5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93378:I6G97 RS04955
gene id: 93378:I6G97_RS04955
uniprot id: A0A376DNG0
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of L-fuculose.

93378:I6G97 RS01505
gene id: 93378:I6G97_RS01505
uniprot id: A0A376D6T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

93378:I6G97 RS14960
gene id: 93378:I6G97_RS14960
uniprot id: A0A376DBF8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4 family.
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: Membrane

93378:I6G97 RS08610
gene id: 93378:I6G97_RS08610
uniprot id: A0A376DIK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

93378:I6G97 RS06985
gene id: 93378:I6G97_RS06985
uniprot id: A0A376DK73
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

93378:I6G97 RS04535
gene id: 93378:I6G97_RS04535
uniprot id: A0A376DMK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

93378:I6G97 RS06735
gene id: 93378:I6G97_RS06735
uniprot id: A0A376DLV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

93378:I6G97 RS05270
gene id: 93378:I6G97_RS05270
uniprot id: A0A376DLT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm
messages: Monomer.

93378:I6G97 RS05055
gene id: 93378:I6G97_RS05055
uniprot id: A0A376DNZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

93378:I6G97 RS13860
gene id: 93378:I6G97_RS13860
uniprot id: A0A376DDG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

93378:I6G97 RS10365
gene id: 93378:I6G97_RS10365
uniprot id: A0A376DGR4
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

93378:I6G97 RS12985
gene id: 93378:I6G97_RS12985
uniprot id: A0A376DDV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family. NanA subfamily.
messages: Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.
messages: Cytoplasm
messages: Homotetramer.

93378:I6G97 RS12060
gene id: 93378:I6G97_RS12060
uniprot id: A0A376DFN1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

93378:I6G97 RS10995
gene id: 93378:I6G97_RS10995
uniprot id: A0A376DGA2
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

93378:I6G97 RS08630
gene id: 93378:I6G97_RS08630
uniprot id: A0A376DJQ8
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

93378:I6G97 RS03105
gene id: 93378:I6G97_RS03105
uniprot id: A0A376D5N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

93378:I6G97 RS12825
gene id: 93378:I6G97_RS12825
uniprot id: A0A376DEQ4
names: Similarity
messages: Belongs to the hyi family.

93378:I6G97 RS02520
gene id: 93378:I6G97_RS02520
uniprot id: A0A376D6F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhE family.
messages: Cytoplasm
messages: Necessary for formate dehydrogenase activity.

93378:I6G97 RS04620
gene id: 93378:I6G97_RS04620
uniprot id: A0A376DPE9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

93378:I6G97 RS09715
gene id: 93378:I6G97_RS09715
uniprot id: A0A376DJB9
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

93378:I6G97 RS10730
gene id: 93378:I6G97_RS10730
uniprot id: A0A376DGF6
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS07970
gene id: 93378:I6G97_RS07970
uniprot id: A0A376DJA5
names: Similarity
messages: Belongs to the heat shock protein 70 family.

93378:I6G97 RS12350
gene id: 93378:I6G97_RS12350
uniprot id: A0A376DEK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxine kinase family. PdxY subfamily.
messages: Homodimer.
messages: Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.

93378:I6G97 RS02025
gene id: 93378:I6G97_RS02025
uniprot id: A0A376D696
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

93378:I6G97 RS12545
gene id: 93378:I6G97_RS12545
uniprot id: A0A376DED4
names: Similarity
messages: Belongs to the TPP enzyme family.

93378:I6G97 RS02570
gene id: 93378:I6G97_RS02570
uniprot id: A0A376D6K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. DtpB subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Proton-dependent permease that transports di- and tripeptides.

93378:I6G97 RS13655
gene id: 93378:I6G97_RS13655
uniprot id: A0A376DDW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

93378:I6G97 RS07080
gene id: 93378:I6G97_RS07080
uniprot id: A0A376DLH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

93378:I6G97 RS11020
gene id: 93378:I6G97_RS11020
uniprot id: A0A376DG90
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

93378:I6G97 RS07210
gene id: 93378:I6G97_RS07210
uniprot id: A0A376DJZ9
names: Function
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.

93378:I6G97 RS14545
gene id: 93378:I6G97_RS14545
uniprot id: A0A376DDY4
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS06590
gene id: 93378:I6G97_RS06590
uniprot id: A0A376DKN8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

93378:I6G97 RS02770
gene id: 93378:I6G97_RS02770
uniprot id: A0A376D6K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AcsB/BcsB family.
messages: Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP).
messages: Cell inner membrane
messages: Tightly associated with the cellulose synthase catalytic subunit.

93378:I6G97 RS11275
gene id: 93378:I6G97_RS11275
uniprot id: A0A376DH16
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS15480
gene id: 93378:I6G97_RS15480
uniprot id: A0A376DCJ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.
messages: Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin.

93378:I6G97 RS11570
gene id: 93378:I6G97_RS11570
uniprot id: A0A376DGQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

93378:I6G97 RS02975
gene id: 93378:I6G97_RS02975
uniprot id: A0A376D5T6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

93378:I6G97 RS11435
gene id: 93378:I6G97_RS11435
uniprot id: A0A376DGB7
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

93378:I6G97 RS03660
gene id: 93378:I6G97_RS03660
uniprot id: A0A376DQ96
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

93378:I6G97 RS17025
gene id: 93378:I6G97_RS17025
uniprot id: A0A376D8X7
names: Cofactor
names: Function
messages: Binds 1 [2Fe-2S] cluster.
messages: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.

93378:I6G97 RS07100
gene id: 93378:I6G97_RS07100
uniprot id: A0A376DL76
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

93378:I6G97 RS01865
gene id: 93378:I6G97_RS01865
uniprot id: A0A376D7Q7
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

93378:I6G97 RS15065
gene id: 93378:I6G97_RS15065
uniprot id: A0A376DCB8
names: Similarity
messages: Belongs to the UPF0304 family.

93378:I6G97 RS12295
gene id: 93378:I6G97_RS12295
uniprot id: A0A376DEU1
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

93378:I6G97 RS03495
gene id: 93378:I6G97_RS03495
uniprot id: A0A376DN23
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS05840
gene id: 93378:I6G97_RS05840
uniprot id: A0A376DLI3
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

93378:I6G97 RS04275
gene id: 93378:I6G97_RS04275
uniprot id: A0A376DMN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 3'-5' exonuclease that prefers single-stranded DNA and RNA. May play a role in the H(2)O(2)-induced DNA damage repair.
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily.
messages: Cytoplasm
messages: Monomer.

93378:I6G97 RS09420
gene id: 93378:I6G97_RS09420
uniprot id: A0A376DH89
names: Subcellular Location Annotation
messages: Cell inner membrane

93378:I6G97 RS07265
gene id: 93378:I6G97_RS07265
uniprot id: A0A376DL22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Syd family.
messages: Cell inner membrane
messages: Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.

93378:I6G97 RS14340
gene id: 93378:I6G97_RS14340
uniprot id: A0A376DBW2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

93378:I6G97 RS06795
gene id: 93378:I6G97_RS06795
uniprot id: A0A376DKH4
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

93378:I6G97 RS02035
gene id: 93378:I6G97_RS02035
uniprot id: A0A376D5Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

93378:I6G97 RS15605
gene id: 93378:I6G97_RS15605
uniprot id: A0A376DAR4
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS11725
gene id: 93378:I6G97_RS11725
uniprot id: A0A376DHC3
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

93378:I6G97 RS08560
gene id: 93378:I6G97_RS08560
uniprot id: A0A376DIM0
names: Similarity
messages: Belongs to the UPF0339 family. Duplicated subfamily.

93378:I6G97 RS02850
gene id: 93378:I6G97_RS02850
uniprot id: A0A376D5D0
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS07550
gene id: 93378:I6G97_RS07550
uniprot id: A0A376DJK5
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS08415
gene id: 93378:I6G97_RS08415
uniprot id: A0A376DIS9
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

93378:I6G97 RS05255
gene id: 93378:I6G97_RS05255
uniprot id: A0A376DLU1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

93378:I6G97 RS09575
gene id: 93378:I6G97_RS09575
uniprot id: A0A376DH32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

93378:I6G97 RS13750
gene id: 93378:I6G97_RS13750
uniprot id: A0A376DDK2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

93378:I6G97 RS00995
gene id: 93378:I6G97_RS00995
uniprot id: A0A376D756
names: Similarity
messages: Belongs to the peptidase U62 family.

93378:I6G97 RS12700
gene id: 93378:I6G97_RS12700
uniprot id: A0A376DE70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

93378:I6G97 RS05135
gene id: 93378:I6G97_RS05135
uniprot id: A0A376DLW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FrdD family.
messages: Cell membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.

93378:I6G97 RS07790
gene id: 93378:I6G97_RS07790
uniprot id: A0A376DJH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DeoC/FbaB aldolase family.
messages: Cytoplasm
messages: Homodecamer.
messages: Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the transfer of an acetyl moiety from 3-hydroxy-5-phosphonooxypentane-2,4-dione to CoA to form glycerone phosphate and acetyl-CoA.

93378:I6G97 RS06645
gene id: 93378:I6G97_RS06645
uniprot id: A0A376DLZ4
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

93378:I6G97 RS02270
gene id: 93378:I6G97_RS02270
uniprot id: A0A376D5Z1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

93378:I6G97 RS01110
gene id: 93378:I6G97_RS01110
uniprot id: A0A376D7A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

93378:I6G97 RS07870
gene id: 93378:I6G97_RS07870
uniprot id: A0A376DJD7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93378:I6G97 RS04125
gene id: 93378:I6G97_RS04125
uniprot id: A0A376DMU0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD, in which XerC interacts with XerD via its C-terminal region, XerD interacts with XerC via its C-terminal region and so on.
messages: FtsK may regulate the catalytic switch between XerC and XerD in the heterotetrameric complex during the two steps of the recombination process.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC specifically exchanges the top DNA strands.

93378:I6G97 RS16985
gene id: 93378:I6G97_RS16985
uniprot id: A0A376D8X8
names: Similarity
messages: Belongs to the peptidase M17 family.

93378:I6G97 RS12815
gene id: 93378:I6G97_RS12815
uniprot id: A0A376DE71
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

93378:I6G97 RS15990
gene id: 93378:I6G97_RS15990
uniprot id: A0A376DC27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

93378:I6G97 RS03410
gene id: 93378:I6G97_RS03410
uniprot id: A0A376DQH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

93378:I6G97 RS05395
gene id: 93378:I6G97_RS05395
uniprot id: A0A376DLV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Homodimer.

93378:I6G97 RS12420
gene id: 93378:I6G97_RS12420
uniprot id: A0A376DGJ2
names: Domain
names: Function
names: Subunit
messages: Consists of two structural and functional domains: an N-terminal DNA-binding domain, approximately the first 60 residues, and a larger C-terminal domain, approximately 280 residues, which imparts the function of corepressor binding and oligomerization.
messages: Homodimer.
messages: Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.

93378:I6G97 RS11590
gene id: 93378:I6G97_RS11590
uniprot id: A0A376DGI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93378:I6G97 RS16120
gene id: 93378:I6G97_RS16120
uniprot id: A0A376DAB8
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

93378:I6G97 RS04170
gene id: 93378:I6G97_RS04170
uniprot id: A0A376DMP9
names: Similarity
messages: Belongs to the Rht family.

93378:I6G97 RS15900
gene id: 93378:I6G97_RS15900
uniprot id: A0A376DA52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth.

93378:I6G97 RS10535
gene id: 93378:I6G97_RS10535
uniprot id: A0A376DG57
names: Similarity
messages: Belongs to the UPF0303 family.

93378:I6G97 RS06840
gene id: 93378:I6G97_RS06840
uniprot id: A0A376DLI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

93378:I6G97 RS10635
gene id: 93378:I6G97_RS10635
uniprot id: A0A376DIG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

93378:I6G97 RS10470
gene id: 93378:I6G97_RS10470
uniprot id: A0A376DG76
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

93378:I6G97 RS16515
gene id: 93378:I6G97_RS16515
uniprot id: A0A376D9Z4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

93378:I6G97 RS16155
gene id: 93378:I6G97_RS16155
uniprot id: A0A376DAR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

93378:I6G97 RS16830
gene id: 93378:I6G97_RS16830
uniprot id: A0A376D963
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dGTPase family. Type 1 subfamily.
messages: Homotetramer.
messages: dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs.

93378:I6G97 RS11895
gene id: 93378:I6G97_RS11895
uniprot id: A0A376DH74
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

93378:I6G97 RS13090
gene id: 93378:I6G97_RS13090
uniprot id: A0A376DDS6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

93378:I6G97 RS13190
gene id: 93378:I6G97_RS13190
uniprot id: A0A376DDU9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

93378:I6G97 RS01010
gene id: 93378:I6G97_RS01010
uniprot id: A0A376D7F4
names: Similarity
messages: Belongs to the barstar family.

93378:I6G97 RS07510
gene id: 93378:I6G97_RS07510
uniprot id: A0A376DJS0
names: Similarity
messages: Belongs to the P(II) protein family.

93378:I6G97 RS02380
gene id: 93378:I6G97_RS02380
uniprot id: A0A376D6H7
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

93378:I6G97 RS15305
gene id: 93378:I6G97_RS15305
uniprot id: A0A376DAE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS02365
gene id: 93378:I6G97_RS02365
uniprot id: A0A376D5U5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

93378:I6G97 RS04685
gene id: 93378:I6G97_RS04685
uniprot id: A0A376DMB2
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

93378:I6G97 RS00175
gene id: 93378:I6G97_RS00175
uniprot id: A0A376J0U7
names: Similarity
messages: Belongs to the antirestriction protein family.

93378:I6G97 RS01710
gene id: 93378:I6G97_RS01710
uniprot id: A0A376D7C3
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

93378:I6G97 RS13250
gene id: 93378:I6G97_RS13250
uniprot id: A0A376DDL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

93378:I6G97 RS15020
gene id: 93378:I6G97_RS15020
uniprot id: A0A376DB73
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93378:I6G97 RS03185
gene id: 93378:I6G97_RS03185
uniprot id: A0A376D4X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcrB family.
messages: Cell membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis. Essential for lipoprotein maturation under conditions where membrane fluidity may be altered.

93378:I6G97 RS11280
gene id: 93378:I6G97_RS11280
uniprot id: A0A376DFZ8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport.

93378:I6G97 RS07855
gene id: 93378:I6G97_RS07855
uniprot id: A0A376DK05
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

93378:I6G97 RS12085
gene id: 93378:I6G97_RS12085
uniprot id: A0A376DEX3
names: Similarity
messages: Belongs to the peptidase S1B family.

93378:I6G97 RS14715
gene id: 93378:I6G97_RS14715
uniprot id: A0A376DBH0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

93378:I6G97 RS05885
gene id: 93378:I6G97_RS05885
uniprot id: A0A376DLH3
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

93378:I6G97 RS04390
gene id: 93378:I6G97_RS04390
uniprot id: A0A376DNY8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS16670
gene id: 93378:I6G97_RS16670
uniprot id: A0A376D9C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E.
messages: Belongs to the RseA family.
messages: Cell inner membrane
messages: Interacts 1:1 with ECF RNA polymerase sigma-E (RpoE); this inhibits the interaction of sigma-E with the RNA polymerase catalytic core and leads to a decreased expression of sigma-E-regulated genes. Interacts with RseB.

93378:I6G97 RS14800
gene id: 93378:I6G97_RS14800
uniprot id: A0A376DBQ7
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

93378:I6G97 RS12340
gene id: 93378:I6G97_RS12340
uniprot id: A0A376DFR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. DtpA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Proton-dependent permease that transports di- and tripeptides.

93378:I6G97 RS13010
gene id: 93378:I6G97_RS13010
uniprot id: A0A376DDI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93378:I6G97 RS02415
gene id: 93378:I6G97_RS02415
uniprot id: A0A376D6G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

93378:I6G97 RS06340
gene id: 93378:I6G97_RS06340
uniprot id: A0A376DL16
names: Similarity
messages: Belongs to the UPF0102 family.

93378:I6G97 RS04895
gene id: 93378:I6G97_RS04895
uniprot id: A0A376DM92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

93378:I6G97 RS15115
gene id: 93378:I6G97_RS15115
uniprot id: A0A376DBG3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

93378:I6G97 RS12670
gene id: 93378:I6G97_RS12670
uniprot id: A0A376DE75
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93378:I6G97 RS15075
gene id: 93378:I6G97_RS15075
uniprot id: A0A376DB86
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

93378:I6G97 RS16780
gene id: 93378:I6G97_RS16780
uniprot id: A0A376DAC9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93378:I6G97 RS15710
gene id: 93378:I6G97_RS15710
uniprot id: A0A376DAB6
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

93378:I6G97 RS12710
gene id: 93378:I6G97_RS12710
uniprot id: A0A376DF98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the porin LamB (TC 1.B.3) family.
messages: Membrane

93378:I6G97 RS06010
gene id: 93378:I6G97_RS06010
uniprot id: A0A376DME4
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS14425
gene id: 93378:I6G97_RS14425
uniprot id: A0A376DBU2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS15650
gene id: 93378:I6G97_RS15650
uniprot id: A0A376DB72
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.

93378:I6G97 RS03435
gene id: 93378:I6G97_RS03435
uniprot id: A0A376DQG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

93378:I6G97 RS17425
gene id: 93378:I6G97_RS17425
uniprot id: A0A376D8G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

93378:I6G97 RS11575
gene id: 93378:I6G97_RS11575
uniprot id: A0A376DFP6
names: Similarity
messages: Belongs to the UPF0227 family.

93378:I6G97 RS03080
gene id: 93378:I6G97_RS03080
uniprot id: A0A376D780
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

93378:I6G97 RS08810
gene id: 93378:I6G97_RS08810
uniprot id: A0A376DI39
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.
messages: Membrane

93378:I6G97 RS08395
gene id: 93378:I6G97_RS08395
uniprot id: A0A376DJD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

93378:I6G97 RS08845
gene id: 93378:I6G97_RS08845
uniprot id: A0A376DJB8
names: Similarity
messages: Belongs to the acetyltransferase family. YpeA subfamily.

93378:I6G97 RS12385
gene id: 93378:I6G97_RS12385
uniprot id: A0A376DEM3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

93378:I6G97 RS09130
gene id: 93378:I6G97_RS09130
uniprot id: A0A376DHL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

93378:I6G97 RS03575
gene id: 93378:I6G97_RS03575
uniprot id: A0A376DPQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

93378:I6G97 RS07605
gene id: 93378:I6G97_RS07605
uniprot id: A0A376DKA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

93378:I6G97 RS03265
gene id: 93378:I6G97_RS03265
uniprot id: A0A376D4W1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: Monomer. Forms homomultimers of about 100-150 subunits at optimal growth temperatures. Conformation changes to monomers at high temperatures or high ionic concentrations.

93378:I6G97 RS11890
gene id: 93378:I6G97_RS11890
uniprot id: A0A376DGE4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

93378:I6G97 RS07225
gene id: 93378:I6G97_RS07225
uniprot id: A0A376DJN0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

93378:I6G97 RS07410
gene id: 93378:I6G97_RS07410
uniprot id: A0A376DJS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

93378:I6G97 RS08660
gene id: 93378:I6G97_RS08660
uniprot id: A0A376DII3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

93378:I6G97 RS01525
gene id: 93378:I6G97_RS01525
uniprot id: A0A376D7J5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

93378:I6G97 RS13460
gene id: 93378:I6G97_RS13460
uniprot id: A0A376DF32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

93378:I6G97 RS12100
gene id: 93378:I6G97_RS12100
uniprot id: A0A376DEL7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

93378:I6G97 RS03060
gene id: 93378:I6G97_RS03060
uniprot id: A0A376D4U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

93378:I6G97 RS16800
gene id: 93378:I6G97_RS16800
uniprot id: A0A376D9Z3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

93378:I6G97 RS11755
gene id: 93378:I6G97_RS11755
uniprot id: A0A376DHC1
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

93378:I6G97 RS08280
gene id: 93378:I6G97_RS08280
uniprot id: A0A376DIY2
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

93378:I6G97 RS03225
gene id: 93378:I6G97_RS03225
uniprot id: A0A376D719
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

93378:I6G97 RS01085
gene id: 93378:I6G97_RS01085
uniprot id: A0A376D7B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nucleoside:H(+) symporter (NHS) (TC 2.A.1.10) family.
messages: Broad-specificity transporter of purine and pyrimidine nucleosides. Transport is driven by a proton motive force.
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS04615
gene id: 93378:I6G97_RS04615
uniprot id: A0A376DMI9
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS17525
gene id: 93378:I6G97_RS17525
uniprot id: A0A376D9J7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

93378:I6G97 RS09565
gene id: 93378:I6G97_RS09565
uniprot id: A0A376DHI6
names: Similarity
messages: Belongs to the acylphosphatase family.

93378:I6G97 RS06815
gene id: 93378:I6G97_RS06815
uniprot id: A0A376DKH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

93378:I6G97 RS08450
gene id: 93378:I6G97_RS08450
uniprot id: A0A376DIH4
names: Similarity
messages: Belongs to the band 7/mec-2 family.

93378:I6G97 RS12450
gene id: 93378:I6G97_RS12450
uniprot id: A0A376DE63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

93378:I6G97 RS12525
gene id: 93378:I6G97_RS12525
uniprot id: A0A376DEJ1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS05505
gene id: 93378:I6G97_RS05505
uniprot id: A0A376DLK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

93378:I6G97 RS06320
gene id: 93378:I6G97_RS06320
uniprot id: A0A376DL27
names: Function
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.

93378:I6G97 RS10355
gene id: 93378:I6G97_RS10355
uniprot id: A0A376DHD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS16905
gene id: 93378:I6G97_RS16905
uniprot id: A0A376D9U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

93378:I6G97 RS10590
gene id: 93378:I6G97_RS10590
uniprot id: A0A376DGI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.
messages: Cell membrane
messages: Membrane

93378:I6G97 RS12205
gene id: 93378:I6G97_RS12205
uniprot id: A0A376DFR8
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS12840
gene id: 93378:I6G97_RS12840
uniprot id: A0A376DE62
names: Similarity
messages: Belongs to the FrmR/RcnR family.

93378:I6G97 RS14495
gene id: 93378:I6G97_RS14495
uniprot id: A0A376DBZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

93378:I6G97 RS14165
gene id: 93378:I6G97_RS14165
uniprot id: A0A376DCA9
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

93378:I6G97 RS10435
gene id: 93378:I6G97_RS10435
uniprot id: A0A376DIM8
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

93378:I6G97 RS11940
gene id: 93378:I6G97_RS11940
uniprot id: A0A376DFC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

93378:I6G97 RS14210
gene id: 93378:I6G97_RS14210
uniprot id: A0A376DCD5
names: Similarity
messages: Belongs to the ClpA/ClpB family.

93378:I6G97 RS02045
gene id: 93378:I6G97_RS02045
uniprot id: A0A376D758
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

93378:I6G97 RS04100
gene id: 93378:I6G97_RS04100
uniprot id: A0A376DMY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-1 family.
messages: Cytoplasm

93378:I6G97 RS03430
gene id: 93378:I6G97_RS03430
uniprot id: A0A376DNJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

93378:I6G97 RS10905
gene id: 93378:I6G97_RS10905
uniprot id: A0A376DFT4
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

93378:I6G97 RS16025
gene id: 93378:I6G97_RS16025
uniprot id: A0A376DAD4
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

93378:I6G97 RS09340
gene id: 93378:I6G97_RS09340
uniprot id: A0A376DHM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

93378:I6G97 RS11135
gene id: 93378:I6G97_RS11135
uniprot id: A0A376DFU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

93378:I6G97 RS05545
gene id: 93378:I6G97_RS05545
uniprot id: A0A376DM87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiV subfamily.
messages: Forms an heterodimer with UbiU.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

93378:I6G97 RS11775
gene id: 93378:I6G97_RS11775
uniprot id: A0A376DF81
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

93378:I6G97 RS08215
gene id: 93378:I6G97_RS08215
uniprot id: A0A376DK76
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

93378:I6G97 RS02175
gene id: 93378:I6G97_RS02175
uniprot id: A0A376D634
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

93378:I6G97 RS06870
gene id: 93378:I6G97_RS06870
uniprot id: A0A376DLH7
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
messages: Repressed under conditions of excess protein secretion capacity and derepressed when protein secretion becomes limiting. This is regulated by SecM.

93378:I6G97 RS10795
gene id: 93378:I6G97_RS10795
uniprot id: A0A376DGZ7
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

93378:I6G97 RS17240
gene id: 93378:I6G97_RS17240
uniprot id: A0A376D8N8
names: Similarity
messages: Belongs to the transglycosylase Slt family.

93378:I6G97 RS07385
gene id: 93378:I6G97_RS07385
uniprot id: A0A376DJT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

93378:I6G97 RS07570
gene id: 93378:I6G97_RS07570
uniprot id: A0A376DJQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
messages: Membrane

93378:I6G97 RS08805
gene id: 93378:I6G97_RS08805
uniprot id: A0A376DJD2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapB family.
messages: Binds 2 heme C groups per subunit.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Electron transfer subunit of the periplasmic nitrate reductase complex NapAB.
messages: Periplasm

93378:I6G97 RS15325
gene id: 93378:I6G97_RS15325
uniprot id: A0A376DAD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

93378:I6G97 RS06500
gene id: 93378:I6G97_RS06500
uniprot id: A0A376DKD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

93378:I6G97 RS02610
gene id: 93378:I6G97_RS02610
uniprot id: A0A376D6B4
names: Similarity
messages: Belongs to the FGGY kinase family.

93378:I6G97 RS06515
gene id: 93378:I6G97_RS06515
uniprot id: A0A376DKT2
names: Similarity
messages: Belongs to the threonine synthase family.

93378:I6G97 RS15580
gene id: 93378:I6G97_RS15580
uniprot id: A0A376DBK4
names: Similarity
messages: Belongs to the sulfatase family.

93378:I6G97 RS14955
gene id: 93378:I6G97_RS14955
uniprot id: A0A376DCD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

93378:I6G97 RS04425
gene id: 93378:I6G97_RS04425
uniprot id: A0A376DPK5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

93378:I6G97 RS14045
gene id: 93378:I6G97_RS14045
uniprot id: A0A376DD90
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS11340
gene id: 93378:I6G97_RS11340
uniprot id: A0A376DFT8
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS17225
gene id: 93378:I6G97_RS17225
uniprot id: A0A376D8N2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

93378:I6G97 RS17010
gene id: 93378:I6G97_RS17010
uniprot id: A0A376D8W6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 2 iron ions per dimer. The dimer may bind additional iron ions.
messages: Homodimer; may form tetramers and higher multimers.
messages: Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.

93378:I6G97 RS12750
gene id: 93378:I6G97_RS12750
uniprot id: A0A376DE50
names: Similarity
messages: Belongs to the universal stress protein A family.

93378:I6G97 RS08670
gene id: 93378:I6G97_RS08670
uniprot id: A0A376DJ30
names: Similarity
messages: Belongs to the ArsC family.

93378:I6G97 RS08865
gene id: 93378:I6G97_RS08865
uniprot id: A0A376DHS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

93378:I6G97 RS13950
gene id: 93378:I6G97_RS13950
uniprot id: A0A376DDU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

93378:I6G97 RS08475
gene id: 93378:I6G97_RS08475
uniprot id: A0A376DIG3
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

93378:I6G97 RS04520
gene id: 93378:I6G97_RS04520
uniprot id: A0A376DMF5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.

93378:I6G97 RS11655
gene id: 93378:I6G97_RS11655
uniprot id: A0A376DFL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93378:I6G97 RS11630
gene id: 93378:I6G97_RS11630
uniprot id: A0A376DF26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

93378:I6G97 RS15830
gene id: 93378:I6G97_RS15830
uniprot id: A0A376DA65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

93378:I6G97 RS08070
gene id: 93378:I6G97_RS08070
uniprot id: A0A376DJ63
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS07030
gene id: 93378:I6G97_RS07030
uniprot id: A0A376DLJ5
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS10735
gene id: 93378:I6G97_RS10735
uniprot id: A0A376DH17
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

93378:I6G97 RS17550
gene id: 93378:I6G97_RS17550
uniprot id: A0A376D9I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MutH family.
messages: Cytoplasm
messages: Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.

93378:I6G97 RS02005
gene id: 93378:I6G97_RS02005
uniprot id: A0A376D8H3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

93378:I6G97 RS01650
gene id: 93378:I6G97_RS01650
uniprot id: A0A376D7E3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

93378:I6G97 RS12010
gene id: 93378:I6G97_RS12010
uniprot id: A0A376DER2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

93378:I6G97 RS06070
gene id: 93378:I6G97_RS06070
uniprot id: A0A376DL85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

93378:I6G97 RS01350
gene id: 93378:I6G97_RS01350
uniprot id: A0A376D6R8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

93378:I6G97 RS08460
gene id: 93378:I6G97_RS08460
uniprot id: A0A376DIQ6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS06275
gene id: 93378:I6G97_RS06275
uniprot id: A0A376DLP1
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

93378:I6G97 RS01125
gene id: 93378:I6G97_RS01125
uniprot id: A0A376D7M0
names: Similarity
messages: Belongs to the HupH/HyaF family.

93378:I6G97 RS00925
gene id: 93378:I6G97_RS00925
uniprot id: A0A376D8B2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LysR transcriptional regulatory family.
messages: Controls the transcription of genes involved in arginine and lysine metabolism.
messages: Homodimer.

93378:I6G97 RS01150
gene id: 93378:I6G97_RS01150
uniprot id: A0A376D7K9
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

93378:I6G97 RS03000
gene id: 93378:I6G97_RS03000
uniprot id: A0A376D4W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

93378:I6G97 RS04245
gene id: 93378:I6G97_RS04245
uniprot id: A0A376DMP3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

93378:I6G97 RS17175
gene id: 93378:I6G97_RS17175
uniprot id: A0A376D8K9
names: Similarity
messages: Belongs to the antirestriction protein family.

93378:I6G97 RS06885
gene id: 93378:I6G97_RS06885
uniprot id: A0A376DMA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

93378:I6G97 RS04585
gene id: 93378:I6G97_RS04585
uniprot id: A0A376DPF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins.
messages: Periplasm

93378:I6G97 RS05385
gene id: 93378:I6G97_RS05385
uniprot id: A0A376DMD8
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

93378:I6G97 RS10265
gene id: 93378:I6G97_RS10265
uniprot id: A0A376DGU5
names: Subcellular Location Annotation
messages: Cell inner membrane

93378:I6G97 RS03600
gene id: 93378:I6G97_RS03600
uniprot id: A0A376DN69
names: Function
names: Similarity
names: Subunit
messages: A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis.
messages: Belongs to the YihI family.
messages: Interacts with Der.

93378:I6G97 RS14995
gene id: 93378:I6G97_RS14995
uniprot id: A0A376DAZ7
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

93378:I6G97 RS05020
gene id: 93378:I6G97_RS05020
uniprot id: A0A376DNE2
names: Subcellular Location Annotation
messages: Cell inner membrane

93378:I6G97 RS12630
gene id: 93378:I6G97_RS12630
uniprot id: A0A376DFD0
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS03045
gene id: 93378:I6G97_RS03045
uniprot id: A0A376D5R7
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

93378:I6G97 RS08000
gene id: 93378:I6G97_RS08000
uniprot id: A0A376DJB1
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS07060
gene id: 93378:I6G97_RS07060
uniprot id: A0A376DKB8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

93378:I6G97 RS10510
gene id: 93378:I6G97_RS10510
uniprot id: A0A376DGL1
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

93378:I6G97 RS03840
gene id: 93378:I6G97_RS03840
uniprot id: A0A376DNQ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

93378:I6G97 RS03695
gene id: 93378:I6G97_RS03695
uniprot id: A0A376DN75
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

93378:I6G97 RS03090
gene id: 93378:I6G97_RS03090
uniprot id: A0A376D5P5
names: Subcellular Location Annotation
messages: Cell inner membrane

93378:I6G97 RS09210
gene id: 93378:I6G97_RS09210
uniprot id: A0A376DHW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

93378:I6G97 RS09200
gene id: 93378:I6G97_RS09200
uniprot id: A0A376DJX4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

93378:I6G97 RS16700
gene id: 93378:I6G97_RS16700
uniprot id: A0A376D9P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

93378:I6G97 RS09005
gene id: 93378:I6G97_RS09005
uniprot id: A0A376DI68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. OpgH subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
messages: Membrane

93378:I6G97 RS04750
gene id: 93378:I6G97_RS04750
uniprot id: A0A376DP94
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

93378:I6G97 RS08365
gene id: 93378:I6G97_RS08365
uniprot id: A0A376DIU5
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

93378:I6G97 RS07000
gene id: 93378:I6G97_RS07000
uniprot id: A0A376DLK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS16210
gene id: 93378:I6G97_RS16210
uniprot id: A0A376DB02
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

93378:I6G97 RS13255
gene id: 93378:I6G97_RS13255
uniprot id: A0A376DEQ6
names: Similarity
messages: Belongs to the PrpF family.

93378:I6G97 RS03855
gene id: 93378:I6G97_RS03855
uniprot id: A0A376DN08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

93378:I6G97 RS12655
gene id: 93378:I6G97_RS12655
uniprot id: A0A376DE61
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

93378:I6G97 RS11865
gene id: 93378:I6G97_RS11865
uniprot id: A0A376DFV2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

93378:I6G97 RS10325
gene id: 93378:I6G97_RS10325
uniprot id: A0A376DHU3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhD family.
messages: Cytoplasm
messages: Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.
messages: The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA.

93378:I6G97 RS10605
gene id: 93378:I6G97_RS10605
uniprot id: A0A376DGI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

93378:I6G97 RS16840
gene id: 93378:I6G97_RS16840
uniprot id: A0A376D8Y2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BtuF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.
messages: Periplasm
messages: The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).

93378:I6G97 RS07260
gene id: 93378:I6G97_RS07260
uniprot id: A0A376DJY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

93378:I6G97 RS03245
gene id: 93378:I6G97_RS03245
uniprot id: A0A376D615
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

93378:I6G97 RS13730
gene id: 93378:I6G97_RS13730
uniprot id: A0A376DCX1
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

93378:I6G97 RS06250
gene id: 93378:I6G97_RS06250
uniprot id: A0A376DN10
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

93378:I6G97 RS04270
gene id: 93378:I6G97_RS04270
uniprot id: A0A376DMB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

93378:I6G97 RS16845
gene id: 93378:I6G97_RS16845
uniprot id: A0A376DAA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

93378:I6G97 RS14330
gene id: 93378:I6G97_RS14330
uniprot id: A0A376DC57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

93378:I6G97 RS10790
gene id: 93378:I6G97_RS10790
uniprot id: A0A376DGD3
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

93378:I6G97 RS12395
gene id: 93378:I6G97_RS12395
uniprot id: A0A376DE87
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS03170
gene id: 93378:I6G97_RS03170
uniprot id: A0A376D644
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS02560
gene id: 93378:I6G97_RS02560
uniprot id: A0A376D5G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein B family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

93378:I6G97 RS05145
gene id: 93378:I6G97_RS05145
uniprot id: A0A376DNW1
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

93378:I6G97 RS01960
gene id: 93378:I6G97_RS01960
uniprot id: A0A376D628
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

93378:I6G97 RS04975
gene id: 93378:I6G97_RS04975
uniprot id: A0A376DMQ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldolase class II family. AraD/FucA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the degradation of L-fucose and D-arabinose. Catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.

93378:I6G97 RS02620
gene id: 93378:I6G97_RS02620
uniprot id: A0A376D7S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

93378:I6G97 RS16815
gene id: 93378:I6G97_RS16815
uniprot id: A0A376DB83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93378:I6G97 RS04900
gene id: 93378:I6G97_RS04900
uniprot id: A0A376DM43
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

93378:I6G97 RS06030
gene id: 93378:I6G97_RS06030
uniprot id: A0A376DN92
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

93378:I6G97 RS01705
gene id: 93378:I6G97_RS01705
uniprot id: A0A376D6C8
names: Similarity
messages: Belongs to the carbamate kinase family.

93378:I6G97 RS12865
gene id: 93378:I6G97_RS12865
uniprot id: A0A376DE51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

93378:I6G97 RS10660
gene id: 93378:I6G97_RS10660
uniprot id: A0A376DGG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS15070
gene id: 93378:I6G97_RS15070
uniprot id: A0A376DBI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0208 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

93378:I6G97 RS01470
gene id: 93378:I6G97_RS01470
uniprot id: A0A376D7U1
names: Similarity
messages: Belongs to the peptidase U62 family.

93378:I6G97 RS12135
gene id: 93378:I6G97_RS12135
uniprot id: A0A376DET0
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

93378:I6G97 RS03635
gene id: 93378:I6G97_RS03635
uniprot id: A0A376DPN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

93378:I6G97 RS10385
gene id: 93378:I6G97_RS10385
uniprot id: A0A376DGQ3
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS03015
gene id: 93378:I6G97_RS03015
uniprot id: A0A376D6B6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapB family.
messages: Cytoplasm
messages: Homodimer. The ends of the coiled-coil dimer bind to each other, forming polymers. Interacts with FtsZ.
messages: Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.

93378:I6G97 RS12660
gene id: 93378:I6G97_RS12660
uniprot id: A0A376DFC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

93378:I6G97 RS05315
gene id: 93378:I6G97_RS05315
uniprot id: A0A376DLX7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

93378:I6G97 RS07810
gene id: 93378:I6G97_RS07810
uniprot id: A0A376DKG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. AI-2 autoinducer porter (TC 3.A.1.2.8) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

93378:I6G97 RS06880
gene id: 93378:I6G97_RS06880
uniprot id: A0A376DKF2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

93378:I6G97 RS09475
gene id: 93378:I6G97_RS09475
uniprot id: A0A376DHR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PqiA family.
messages: Component of a transport pathway that contributes to membrane integrity.
messages: Membrane

93378:I6G97 RS15875
gene id: 93378:I6G97_RS15875
uniprot id: A0A376DAY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

93378:I6G97 RS01870
gene id: 93378:I6G97_RS01870
uniprot id: A0A376D739
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

93378:I6G97 RS06780
gene id: 93378:I6G97_RS06780
uniprot id: A0A376DLK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster. Acts by binding directly to DNA. May also regulate the expression of genes outside the dcw cluster.
messages: nucleoid

93378:I6G97 RS04770
gene id: 93378:I6G97_RS04770
uniprot id: A0A376DMC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

93378:I6G97 RS10710
gene id: 93378:I6G97_RS10710
uniprot id: A0A376DGA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family. LpxM subfamily.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-(acyl)-lipid IV(A) to form a Kdo(2)-lipid A.
messages: Cell inner membrane

93378:I6G97 RS14010
gene id: 93378:I6G97_RS14010
uniprot id: A0A376DCM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

93378:I6G97 RS00420
gene id: 93378:I6G97_RS00420
uniprot id: A0A376D911
names: Function
names: Similarity
messages: Belongs to the polysaccharide lyase 8 family.
messages: Broad-specificity glycosaminoglycan lyase.

93378:I6G97 RS17100
gene id: 93378:I6G97_RS17100
uniprot id: A0A376D990
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

93378:I6G97 RS11285
gene id: 93378:I6G97_RS11285
uniprot id: A0A376DFU0
names: Similarity
messages: Belongs to the UPF0053 family.

93378:I6G97 RS16625
gene id: 93378:I6G97_RS16625
uniprot id: A0A376DAL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

93378:I6G97 RS05195
gene id: 93378:I6G97_RS05195
uniprot id: A0A376DLV1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

93378:I6G97 RS08940
gene id: 93378:I6G97_RS08940
uniprot id: A0A376DIU1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

93378:I6G97 RS12435
gene id: 93378:I6G97_RS12435
uniprot id: A0A376DFH9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93378:I6G97 RS09105
gene id: 93378:I6G97_RS09105
uniprot id: A0A376DHM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

93378:I6G97 RS16595
gene id: 93378:I6G97_RS16595
uniprot id: A0A376D9G2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

93378:I6G97 RS05030
gene id: 93378:I6G97_RS05030
uniprot id: A0A376DM55
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

93378:I6G97 RS03995
gene id: 93378:I6G97_RS03995
uniprot id: A0A376DNJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

93378:I6G97 RS15880
gene id: 93378:I6G97_RS15880
uniprot id: A0A376D9Y0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

93378:I6G97 RS02185
gene id: 93378:I6G97_RS02185
uniprot id: A0A376D616
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane
messages: Membrane

93378:I6G97 RS16835
gene id: 93378:I6G97_RS16835
uniprot id: A0A376D9Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
messages: Homodimer.

93378:I6G97 RS14765
gene id: 93378:I6G97_RS14765
uniprot id: A0A376DBM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS10640
gene id: 93378:I6G97_RS10640
uniprot id: A0A376DG32
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS17275
gene id: 93378:I6G97_RS17275
uniprot id: A0A376D8T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

93378:I6G97 RS01030
gene id: 93378:I6G97_RS01030
uniprot id: A0A376D8C8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

93378:I6G97 RS16165
gene id: 93378:I6G97_RS16165
uniprot id: A0A376DBY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

93378:I6G97 RS17435
gene id: 93378:I6G97_RS17435
uniprot id: A0A376D8Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

93378:I6G97 RS00900
gene id: 93378:I6G97_RS00900
uniprot id: A0A376D7J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

93378:I6G97 RS06765
gene id: 93378:I6G97_RS06765
uniprot id: A0A376DME9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

93378:I6G97 RS11955
gene id: 93378:I6G97_RS11955
uniprot id: A0A376DF33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

93378:I6G97 RS15280
gene id: 93378:I6G97_RS15280
uniprot id: A0A376DB68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

93378:I6G97 RS02105
gene id: 93378:I6G97_RS02105
uniprot id: A0A376D725
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily.
messages: Cell inner membrane
messages: Interacts with KefB.
messages: Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB.

93378:I6G97 RS17050
gene id: 93378:I6G97_RS17050
uniprot id: A0A376D9M8
names: Caution
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS13520
gene id: 93378:I6G97_RS13520
uniprot id: A0A376DDS7
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

93378:I6G97 RS06180
gene id: 93378:I6G97_RS06180
uniprot id: A0A376DLU0
names: Similarity
names: Subunit
messages: Belongs to the SIS family. GutQ/KpsF subfamily.
messages: Homotetramer.

93378:I6G97 RS17165
gene id: 93378:I6G97_RS17165
uniprot id: A0A376D8Y5
names: Similarity
messages: Belongs to the UPF0401 family.

93378:I6G97 RS08890
gene id: 93378:I6G97_RS08890
uniprot id: A0A376DK58
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS09610
gene id: 93378:I6G97_RS09610
uniprot id: A0A376DHL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 83 family.
messages: Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

93378:I6G97 RS04570
gene id: 93378:I6G97_RS04570
uniprot id: A0A376DN34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

93378:I6G97 RS08125
gene id: 93378:I6G97_RS08125
uniprot id: A0A376DJ60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

93378:I6G97 RS04550
gene id: 93378:I6G97_RS04550
uniprot id: A0A376DMK8
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

93378:I6G97 RS12775
gene id: 93378:I6G97_RS12775
uniprot id: A0A376DE39
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS15160
gene id: 93378:I6G97_RS15160
uniprot id: A0A376DD16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

93378:I6G97 RS08445
gene id: 93378:I6G97_RS08445
uniprot id: A0A376DJB4
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS13715
gene id: 93378:I6G97_RS13715
uniprot id: A0A376DCX9
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

93378:I6G97 RS14825
gene id: 93378:I6G97_RS14825
uniprot id: A0A376DBJ4
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

93378:I6G97 RS14485
gene id: 93378:I6G97_RS14485
uniprot id: A0A376DC42
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

93378:I6G97 RS09990
gene id: 93378:I6G97_RS09990
uniprot id: A0A376DH21
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.

93378:I6G97 RS17350
gene id: 93378:I6G97_RS17350
uniprot id: A0A376D8R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

93378:I6G97 RS16805
gene id: 93378:I6G97_RS16805
uniprot id: A0A376D8Z3
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS06305
gene id: 93378:I6G97_RS06305
uniprot id: A0A376DME2
names: Similarity
messages: Belongs to the glutamate synthase family.

93378:I6G97 RS11155
gene id: 93378:I6G97_RS11155
uniprot id: A0A376DGL0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

93378:I6G97 RS08615
gene id: 93378:I6G97_RS08615
uniprot id: A0A376DIK4
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

93378:I6G97 RS13980
gene id: 93378:I6G97_RS13980
uniprot id: A0A376DCV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MukE family.
messages: Interacts, and probably forms a ternary complex, with MukF and MukB. The complex formation is stimulated by calcium or magnesium.
messages: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.
messages: nucleoid

93378:I6G97 RS10945
gene id: 93378:I6G97_RS10945
uniprot id: A0A376DI43
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Binds two Mg(2+) per subunit.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

93378:I6G97 RS01965
gene id: 93378:I6G97_RS01965
uniprot id: A0A376D6C5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

93378:I6G97 RS15610
gene id: 93378:I6G97_RS15610
uniprot id: A0A376DAE6
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS14025
gene id: 93378:I6G97_RS14025
uniprot id: A0A376DCU6
names: Similarity
messages: Belongs to the UPF0434 family.

93378:I6G97 RS04150
gene id: 93378:I6G97_RS04150
uniprot id: A0A376DMS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

93378:I6G97 RS05415
gene id: 93378:I6G97_RS05415
uniprot id: A0A376DLM7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

93378:I6G97 RS08250
gene id: 93378:I6G97_RS08250
uniprot id: A0A376DJ09
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

93378:I6G97 RS13585
gene id: 93378:I6G97_RS13585
uniprot id: A0A376DEX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

93378:I6G97 RS13540
gene id: 93378:I6G97_RS13540
uniprot id: A0A376DDR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

93378:I6G97 RS02995
gene id: 93378:I6G97_RS02995
uniprot id: A0A376D7B5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

93378:I6G97 RS05455
gene id: 93378:I6G97_RS05455
uniprot id: A0A376DMB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

93378:I6G97 RS01290
gene id: 93378:I6G97_RS01290
uniprot id: A0A376D8C4
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

93378:I6G97 RS13430
gene id: 93378:I6G97_RS13430
uniprot id: A0A376DDF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

93378:I6G97 RS04000
gene id: 93378:I6G97_RS04000
uniprot id: A0A376DNX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. WecA subfamily.
messages: Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS00370
gene id: 93378:I6G97_RS00370
uniprot id: A0A376D7X7
names: Similarity
messages: Belongs to the HupF/HypC family.

93378:I6G97 RS08235
gene id: 93378:I6G97_RS08235
uniprot id: A0A376DIS7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

93378:I6G97 RS15940
gene id: 93378:I6G97_RS15940
uniprot id: A0A376DAG0
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

93378:I6G97 RS02545
gene id: 93378:I6G97_RS02545
uniprot id: A0A376D6E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.
messages: Membrane

93378:I6G97 RS03160
gene id: 93378:I6G97_RS03160
uniprot id: A0A376D5L5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS05165
gene id: 93378:I6G97_RS05165
uniprot id: A0A376DLW1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

93378:I6G97 RS08170
gene id: 93378:I6G97_RS08170
uniprot id: A0A376DJ25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

93378:I6G97 RS06850
gene id: 93378:I6G97_RS06850
uniprot id: A0A376DLR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

93378:I6G97 RS01405
gene id: 93378:I6G97_RS01405
uniprot id: A0A376D717
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anaerobic G-3-P dehydrogenase subunit B family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor.

93378:I6G97 RS09600
gene id: 93378:I6G97_RS09600
uniprot id: A0A376DJG6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Homohexamer, formed by a dimer of trimers.
messages: In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: In the N-terminal section; belongs to the Fmt family. UDP-L-Ara4N formyltransferase subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS15320
gene id: 93378:I6G97_RS15320
uniprot id: A0A376DBW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

93378:I6G97 RS03350
gene id: 93378:I6G97_RS03350
uniprot id: A0A376DQJ6
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
messages: Homodimer.

93378:I6G97 RS11105
gene id: 93378:I6G97_RS11105
uniprot id: A0A376DGM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

93378:I6G97 RS04315
gene id: 93378:I6G97_RS04315
uniprot id: A0A376DMR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

93378:I6G97 RS07440
gene id: 93378:I6G97_RS07440
uniprot id: A0A376DL39
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

93378:I6G97 RS01855
gene id: 93378:I6G97_RS01855
uniprot id: A0A376D6I3
names: Similarity
messages: Belongs to the DprA/Smf family.

93378:I6G97 RS09155
gene id: 93378:I6G97_RS09155
uniprot id: A0A376DI41
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

93378:I6G97 RS01490
gene id: 93378:I6G97_RS01490
uniprot id: A0A376D837
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

93378:I6G97 RS01015
gene id: 93378:I6G97_RS01015
uniprot id: A0A376D9M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease N1/T1 family.
messages: Secreted

93378:I6G97 RS13005
gene id: 93378:I6G97_RS13005
uniprot id: A0A376DFS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

93378:I6G97 RS07565
gene id: 93378:I6G97_RS07565
uniprot id: A0A376DKY3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

93378:I6G97 RS08470
gene id: 93378:I6G97_RS08470
uniprot id: A0A376DJA6
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS14835
gene id: 93378:I6G97_RS14835
uniprot id: A0A376DBX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

93378:I6G97 RS10405
gene id: 93378:I6G97_RS10405
uniprot id: A0A376DIN9
names: Similarity
messages: Belongs to the class A bacterial acid phosphatase family.

93378:I6G97 RS11635
gene id: 93378:I6G97_RS11635
uniprot id: A0A376DFG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

93378:I6G97 RS15615
gene id: 93378:I6G97_RS15615
uniprot id: A0A376DB58
names: Subcellular Location Annotation
messages: Cytoplasm

93378:I6G97 RS09465
gene id: 93378:I6G97_RS09465
uniprot id: A0A376DIW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

93378:I6G97 RS03825
gene id: 93378:I6G97_RS03825
uniprot id: A0A376DN28
names: Similarity
messages: Belongs to the UPF0758 family. YicR subfamily.

93378:I6G97 RS12380
gene id: 93378:I6G97_RS12380
uniprot id: A0A376DFK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SlyA family.
messages: Homodimer.
messages: Transcription regulator that can specifically activate or repress expression of target genes.

93378:I6G97 RS01160
gene id: 93378:I6G97_RS01160
uniprot id: A0A376D798
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

93378:I6G97 RS15035
gene id: 93378:I6G97_RS15035
uniprot id: A0A376DC32
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

93378:I6G97 RS05205
gene id: 93378:I6G97_RS05205
uniprot id: A0A376DNV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

93378:I6G97 RS14185
gene id: 93378:I6G97_RS14185
uniprot id: A0A376DCE7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

93378:I6G97 RS07480
gene id: 93378:I6G97_RS07480
uniprot id: A0A376DKF4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

93378:I6G97 RS11985
gene id: 93378:I6G97_RS11985
uniprot id: A0A376DH42
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

93378:I6G97 RS15285
gene id: 93378:I6G97_RS15285
uniprot id: A0A376DAN1
names: Similarity
messages: Belongs to the MlaA family.

93378:I6G97 RS10345
gene id: 93378:I6G97_RS10345
uniprot id: A0A376DGB1
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

93378:I6G97 RS17430
gene id: 93378:I6G97_RS17430
uniprot id: A0A376DAM4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm
messages: Homotetramer.

93378:I6G97 RS03650
gene id: 93378:I6G97_RS03650
uniprot id: A0A376DPD0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

93378:I6G97 RS00920
gene id: 93378:I6G97_RS00920
uniprot id: A0A376D7U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

93378:I6G97 RS15195
gene id: 93378:I6G97_RS15195
uniprot id: A0A376DBR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
messages: Membrane

93378:I6G97 RS15105
gene id: 93378:I6G97_RS15105
uniprot id: A0A376DBV5
names: Similarity
messages: Belongs to the GST superfamily.

93378:I6G97 RS02460
gene id: 93378:I6G97_RS02460
uniprot id: A0A376D5T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

93378:I6G97 RS14850
gene id: 93378:I6G97_RS14850
uniprot id: A0A376DCB0
names: Similarity
messages: Belongs to the CinA family.

93378:I6G97 RS00060
gene id: 93378:I6G97_RS00060
uniprot id: A0A376IYA1
names: Function
names: Similarity
messages: Belongs to the FinO family.
messages: One of the components on the FinOP fertility inhibition complex, which inhibits the expression of traJ gene, which in turn regulates the expression of some 20 transfer genes. The transfer genes are responsible for the process, called conjugal transfer, in which DNA is transmitted from one bacterial host to another. RNA-binding that interacts with the traJ mRNA and its antisense RNA, finP, stabilizing finP against endonucleolytic degradation and facilitating sense-antisense RNA recognition.

93378:I6G97 RS08675
gene id: 93378:I6G97_RS08675
uniprot id: A0A376DI93
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

93378:I6G97 RS06430
gene id: 93378:I6G97_RS06430
uniprot id: A0A376DKU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

93378:I6G97 RS03915
gene id: 93378:I6G97_RS03915
uniprot id: A0A376DML8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

93378:I6G97 RS09160
gene id: 93378:I6G97_RS09160
uniprot id: A0A376DIM4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

93378:I6G97 RS06245
gene id: 93378:I6G97_RS06245
uniprot id: A0A376DL04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

93378:I6G97 RS15225
gene id: 93378:I6G97_RS15225
uniprot id: A0A376DAY1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

93378:I6G97 RS08190
gene id: 93378:I6G97_RS08190
uniprot id: A0A376DK86
names: Similarity
messages: Belongs to the UPF0234 family.

93378:I6G97 RS13990
gene id: 93378:I6G97_RS13990
uniprot id: A0A376DDB2
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
messages: Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.

93378:I6G97 RS02845
gene id: 93378:I6G97_RS02845
uniprot id: A0A376D610
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

93378:I6G97 RS14475
gene id: 93378:I6G97_RS14475
uniprot id: A0A376DDA7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

93378:I6G97 RS09020
gene id: 93378:I6G97_RS09020
uniprot id: A0A376DIA0
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

93378:I6G97 RS10275
gene id: 93378:I6G97_RS10275
uniprot id: A0A376DGY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

93378:I6G97 RS14095
gene id: 93378:I6G97_RS14095
uniprot id: A0A376DCS5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

93378:I6G97 RS11205
gene id: 93378:I6G97_RS11205
uniprot id: A0A376DGJ3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

93378:I6G97 RS02285
gene id: 93378:I6G97_RS02285
uniprot id: A0A376D689
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

93378:I6G97 RS16080
gene id: 93378:I6G97_RS16080
uniprot id: A0A376DB47
names: Similarity
messages: Belongs to the asparagine synthetase family.

93378:I6G97 RS09880
gene id: 93378:I6G97_RS09880
uniprot id: A0A376IYJ4
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

93378:I6G97 RS07180
gene id: 93378:I6G97_RS07180
uniprot id: A0A376DJP0
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

93378:I6G97 RS13025
gene id: 93378:I6G97_RS13025
uniprot id: A0A376DDV0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

93378:I6G97 RS11880
gene id: 93378:I6G97_RS11880
uniprot id: A0A376DF87
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

93378:I6G97 RS05005
gene id: 93378:I6G97_RS05005
uniprot id: A0A376DM64
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TorC/TorY family.
messages: Binds 5 heme groups per subunit.
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS05500
gene id: 93378:I6G97_RS05500
uniprot id: A0A376DN17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

93378:I6G97 RS06655
gene id: 93378:I6G97_RS06655
uniprot id: A0A376DK81
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

93378:I6G97 RS14365
gene id: 93378:I6G97_RS14365
uniprot id: A0A376DE44
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

93378:I6G97 RS16710
gene id: 93378:I6G97_RS16710
uniprot id: A0A376D9A4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS11420
gene id: 93378:I6G97_RS11420
uniprot id: A0A376DGW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

93378:I6G97 RS11090
gene id: 93378:I6G97_RS11090
uniprot id: A0A376DH81
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

93378:I6G97 RS16990
gene id: 93378:I6G97_RS16990
uniprot id: A0A376DB23
names: Function
names: Similarity
messages: Belongs to the IscX family.
messages: May function as iron donor in the assembly of iron-sulfur clusters.

93378:I6G97 RS01640
gene id: 93378:I6G97_RS01640
uniprot id: A0A376D7B9
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS15245
gene id: 93378:I6G97_RS15245
uniprot id: A0A376DBA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

93378:I6G97 RS11930
gene id: 93378:I6G97_RS11930
uniprot id: A0A376DF40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

93378:I6G97 RS16230
gene id: 93378:I6G97_RS16230
uniprot id: A0A376DAM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

93378:I6G97 RS09060
gene id: 93378:I6G97_RS09060
uniprot id: A0A376DI22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0299 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

93378:I6G97 RS13510
gene id: 93378:I6G97_RS13510
uniprot id: A0A376DD54
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

93378:I6G97 RS04530
gene id: 93378:I6G97_RS04530
uniprot id: A0A376DMG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

93378:I6G97 RS06925
gene id: 93378:I6G97_RS06925
uniprot id: A0A376DJZ1
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS13095
gene id: 93378:I6G97_RS13095
uniprot id: A0A376DEV9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

93378:I6G97 RS15745
gene id: 93378:I6G97_RS15745
uniprot id: A0A376DB21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.
messages: Belongs to the AcrZ family.
messages: Cell membrane
messages: Part of the AcrA-AcrB-AcrZ-TolC efflux pump, interacts directly with AcrB.

93378:I6G97 RS14600
gene id: 93378:I6G97_RS14600
uniprot id: A0A376DBZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS01635
gene id: 93378:I6G97_RS01635
uniprot id: A0A376D7Y4
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS07360
gene id: 93378:I6G97_RS07360
uniprot id: A0A376DLT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

93378:I6G97 RS05975
gene id: 93378:I6G97_RS05975
uniprot id: A0A376DMQ7
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS10930
gene id: 93378:I6G97_RS10930
uniprot id: A0A376DG66
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

93378:I6G97 RS10610
gene id: 93378:I6G97_RS10610
uniprot id: A0A376DIH7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

93378:I6G97 RS03395
gene id: 93378:I6G97_RS03395
uniprot id: A0A376DP68
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

93378:I6G97 RS01835
gene id: 93378:I6G97_RS01835
uniprot id: A0A376D7F8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

93378:I6G97 RS08690
gene id: 93378:I6G97_RS08690
uniprot id: A0A376DIH3
names: Subcellular Location Annotation
messages: Cytoplasm

93378:I6G97 RS02430
gene id: 93378:I6G97_RS02430
uniprot id: A0A376D6J1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PanZ/PanM family.
messages: Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion.
messages: Interacts with PanD in the presence of CoA.

93378:I6G97 RS14070
gene id: 93378:I6G97_RS14070
uniprot id: A0A376DCK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

93378:I6G97 RS15785
gene id: 93378:I6G97_RS15785
uniprot id: A0A376DC85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

93378:I6G97 RS10425
gene id: 93378:I6G97_RS10425
uniprot id: A0A376DGP4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two zinc ions.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

93378:I6G97 RS13945
gene id: 93378:I6G97_RS13945
uniprot id: A0A376DCJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

93378:I6G97 RS01335
gene id: 93378:I6G97_RS01335
uniprot id: A0A376D7R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YkuD family.
messages: Periplasm

93378:I6G97 RS08715
gene id: 93378:I6G97_RS08715
uniprot id: A0A376DIG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

93378:I6G97 RS11395
gene id: 93378:I6G97_RS11395
uniprot id: A0A376DGW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

93378:I6G97 RS01450
gene id: 93378:I6G97_RS01450
uniprot id: A0A376D946
names: Similarity
messages: Belongs to the RutC family.

93378:I6G97 RS08160
gene id: 93378:I6G97_RS08160
uniprot id: A0A376DIV8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

93378:I6G97 RS15660
gene id: 93378:I6G97_RS15660
uniprot id: A0A376DBH7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

93378:I6G97 RS04835
gene id: 93378:I6G97_RS04835
uniprot id: A0A376DMA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
messages: Monomer.

93378:I6G97 RS06785
gene id: 93378:I6G97_RS06785
uniprot id: A0A376DKI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

93378:I6G97 RS06660
gene id: 93378:I6G97_RS06660
uniprot id: A0A376DKI3
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

93378:I6G97 RS17330
gene id: 93378:I6G97_RS17330
uniprot id: A0A376D8K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

93378:I6G97 RS04940
gene id: 93378:I6G97_RS04940
uniprot id: A0A376DMR2
names: Similarity
messages: Belongs to the UPF0441 family.

93378:I6G97 RS08295
gene id: 93378:I6G97_RS08295
uniprot id: A0A376DIY5
names: Similarity
messages: Belongs to the Hha/YmoA/Cnu family.

93378:I6G97 RS07595
gene id: 93378:I6G97_RS07595
uniprot id: A0A376DJP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Crl family.
messages: Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32.
messages: Cytoplasm

93378:I6G97 RS15845
gene id: 93378:I6G97_RS15845
uniprot id: A0A376DA73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

93378:I6G97 RS13935
gene id: 93378:I6G97_RS13935
uniprot id: A0A376DCP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

93378:I6G97 RS10690
gene id: 93378:I6G97_RS10690
uniprot id: A0A376DIF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

93378:I6G97 RS09190
gene id: 93378:I6G97_RS09190
uniprot id: A0A376DHT3
names: Similarity
messages: Belongs to the UDPGP type 2 family.

93378:I6G97 RS16125
gene id: 93378:I6G97_RS16125
uniprot id: A0A376DA34
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

93378:I6G97 RS10960
gene id: 93378:I6G97_RS10960
uniprot id: A0A376DH58
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

93378:I6G97 RS06980
gene id: 93378:I6G97_RS06980
uniprot id: A0A376DKE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine.

93378:I6G97 RS15995
gene id: 93378:I6G97_RS15995
uniprot id: A0A376D9P7
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS09120
gene id: 93378:I6G97_RS09120
uniprot id: A0A376DI23
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

93378:I6G97 RS12935
gene id: 93378:I6G97_RS12935
uniprot id: A0A376DEL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93378:I6G97 RS09290
gene id: 93378:I6G97_RS09290
uniprot id: A0A376DHP8
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

93378:I6G97 RS09050
gene id: 93378:I6G97_RS09050
uniprot id: A0A376DI67
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion.
messages: Homodimer.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

93378:I6G97 RS06315
gene id: 93378:I6G97_RS06315
uniprot id: A0A376DLN1
names: PTM
names: Subcellular Location Annotation
messages: Activation requires a sequential transfer of a phosphate group from a His in the primary transmitter domain, to an Asp in the receiver domain and to a His in the secondary transmitter domain.
messages: Cell inner membrane

93378:I6G97 RS07540
gene id: 93378:I6G97_RS07540
uniprot id: A0A376DLM4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93378:I6G97 RS03290
gene id: 93378:I6G97_RS03290
uniprot id: A0A376D528
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

93378:I6G97 RS06390
gene id: 93378:I6G97_RS06390
uniprot id: A0A376DL08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TrpR family.
messages: Cytoplasm
messages: Homodimer.
messages: This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.

93378:I6G97 RS05350
gene id: 93378:I6G97_RS05350
uniprot id: A0A376DLQ9
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS17000
gene id: 93378:I6G97_RS17000
uniprot id: A0A376D8Y9
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU.

93378:I6G97 RS03470
gene id: 93378:I6G97_RS03470
uniprot id: A0A376DN33
names: Similarity
names: Subunit
messages: Belongs to the ViaA family.
messages: Possible formation of a ternary complex RavA-ViaA-CadA.

93378:I6G97 RS02980
gene id: 93378:I6G97_RS02980
uniprot id: A0A376D5F9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

93378:I6G97 RS04455
gene id: 93378:I6G97_RS04455
uniprot id: A0A376DM65
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

93378:I6G97 RS10290
gene id: 93378:I6G97_RS10290
uniprot id: A0A376DHV3
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

93378:I6G97 RS11740
gene id: 93378:I6G97_RS11740
uniprot id: A0A376DGC7
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

93378:I6G97 RS06825
gene id: 93378:I6G97_RS06825
uniprot id: A0A376DKF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

93378:I6G97 RS03140
gene id: 93378:I6G97_RS03140
uniprot id: A0A376D4Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

93378:I6G97 RS04610
gene id: 93378:I6G97_RS04610
uniprot id: A0A376DMC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

93378:I6G97 RS08410
gene id: 93378:I6G97_RS08410
uniprot id: A0A376DIS6
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

93378:I6G97 RS16055
gene id: 93378:I6G97_RS16055
uniprot id: A0A376DC11
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS09115
gene id: 93378:I6G97_RS09115
uniprot id: A0A376DJ52
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS14530
gene id: 93378:I6G97_RS14530
uniprot id: A0A376DDZ5
names: Similarity
messages: Belongs to the elongation factor P family.

93378:I6G97 RS03620
gene id: 93378:I6G97_RS03620
uniprot id: A0A376DNA9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

93378:I6G97 RS03710
gene id: 93378:I6G97_RS03710
uniprot id: A0A376DN32
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
messages: Cytoplasm

93378:I6G97 RS02960
gene id: 93378:I6G97_RS02960
uniprot id: A0A376D5U1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

93378:I6G97 RS14575
gene id: 93378:I6G97_RS14575
uniprot id: A0A376DC10
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

93378:I6G97 RS14890
gene id: 93378:I6G97_RS14890
uniprot id: A0A376DBV8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

93378:I6G97 RS14845
gene id: 93378:I6G97_RS14845
uniprot id: A0A376DBN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

93378:I6G97 RS10840
gene id: 93378:I6G97_RS10840
uniprot id: A0A376DFW5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Multifunctional regulator of fatty acid metabolism.

93378:I6G97 RS01385
gene id: 93378:I6G97_RS01385
uniprot id: A0A376D7Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraB family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
messages: Interacts with the C-terminal region of Rne.

93378:I6G97 RS15170
gene id: 93378:I6G97_RS15170
uniprot id: A0A376DBW9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS09335
gene id: 93378:I6G97_RS09335
uniprot id: A0A376DIF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

93378:I6G97 RS06345
gene id: 93378:I6G97_RS06345
uniprot id: A0A376DKK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LpoA family.
messages: Interacts with PBP1a.
messages: Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a).

93378:I6G97 RS03610
gene id: 93378:I6G97_RS03610
uniprot id: A0A376DNA1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family. YidE subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS17440
gene id: 93378:I6G97_RS17440
uniprot id: A0A376D8P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

93378:I6G97 RS10965
gene id: 93378:I6G97_RS10965
uniprot id: A0A376DHC9
names: Similarity
messages: Belongs to the LOG family.

93378:I6G97 RS14590
gene id: 93378:I6G97_RS14590
uniprot id: A0A376DDW5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

93378:I6G97 RS05340
gene id: 93378:I6G97_RS05340
uniprot id: A0A376DLS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

93378:I6G97 RS07765
gene id: 93378:I6G97_RS07765
uniprot id: A0A376DKI8
names: Similarity
messages: Belongs to the RutC family.

93378:I6G97 RS07590
gene id: 93378:I6G97_RS07590
uniprot id: A0A376DKX6
names: Function
names: Similarity
messages: Belongs to the FrsA family.
messages: Catalyzes the hydrolysis of esters.

93378:I6G97 RS06335
gene id: 93378:I6G97_RS06335
uniprot id: A0A376DM13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SIS family. DiaA subfamily.
messages: Homotetramer; dimer of dimers.
messages: Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein.

93378:I6G97 RS02355
gene id: 93378:I6G97_RS02355
uniprot id: A0A376D5W5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

93378:I6G97 RS06600
gene id: 93378:I6G97_RS06600
uniprot id: A0A376DLB2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

93378:I6G97 RS09530
gene id: 93378:I6G97_RS09530
uniprot id: A0A376DI73
names: Subcellular Location Annotation
messages: Cell inner membrane

93378:I6G97 RS05240
gene id: 93378:I6G97_RS05240
uniprot id: A0A376DNU0
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

93378:I6G97 RS12260
gene id: 93378:I6G97_RS12260
uniprot id: A0A376DFD3
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS04960
gene id: 93378:I6G97_RS04960
uniprot id: A0A376DP35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the L-fucose isomerase family.
messages: Converts the aldose L-fucose into the corresponding ketose L-fuculose.
messages: Cytoplasm
messages: Homohexamer.

93378:I6G97 RS14790
gene id: 93378:I6G97_RS14790
uniprot id: A0A376DCV5
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

93378:I6G97 RS10685
gene id: 93378:I6G97_RS10685
uniprot id: A0A376DGG0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

93378:I6G97 RS06350
gene id: 93378:I6G97_RS06350
uniprot id: A0A376DKV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

93378:I6G97 RS14565
gene id: 93378:I6G97_RS14565
uniprot id: A0A376DDX5
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS05410
gene id: 93378:I6G97_RS05410
uniprot id: A0A376DLV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

93378:I6G97 RS09320
gene id: 93378:I6G97_RS09320
uniprot id: A0A376DJ33
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

93378:I6G97 RS17515
gene id: 93378:I6G97_RS17515
uniprot id: A0A376D962
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.

93378:I6G97 RS12455
gene id: 93378:I6G97_RS12455
uniprot id: A0A376DEI0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

93378:I6G97 RS08655
gene id: 93378:I6G97_RS08655
uniprot id: A0A376DII6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

93378:I6G97 RS03645
gene id: 93378:I6G97_RS03645
uniprot id: A0A376DN99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell membrane
messages: Membrane

93378:I6G97 RS04880
gene id: 93378:I6G97_RS04880
uniprot id: A0A376DM35
names: Similarity
messages: Belongs to the UPF0235 family.

93378:I6G97 RS11325
gene id: 93378:I6G97_RS11325
uniprot id: A0A376DFE1
names: Function
messages: Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.

93378:I6G97 RS11460
gene id: 93378:I6G97_RS11460
uniprot id: A0A376DGA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

93378:I6G97 RS14935
gene id: 93378:I6G97_RS14935
uniprot id: A0A376DCN7
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

93378:I6G97 RS12210
gene id: 93378:I6G97_RS12210
uniprot id: A0A376DEU2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

93378:I6G97 RS08750
gene id: 93378:I6G97_RS08750
uniprot id: A0A376DI56
names: Similarity
messages: Belongs to the ArsC family.

93378:I6G97 RS12765
gene id: 93378:I6G97_RS12765
uniprot id: A0A376DF77
names: Subcellular Location Annotation
messages: Cell inner membrane

93378:I6G97 RS02535
gene id: 93378:I6G97_RS02535
uniprot id: A0A376D6C2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS10700
gene id: 93378:I6G97_RS10700
uniprot id: A0A376DGE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 9 family.
messages: Periplasm

93378:I6G97 RS01975
gene id: 93378:I6G97_RS01975
uniprot id: A0A376D6B5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

93378:I6G97 RS13595
gene id: 93378:I6G97_RS13595
uniprot id: A0A376DD17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

93378:I6G97 RS08230
gene id: 93378:I6G97_RS08230
uniprot id: A0A376DJL1
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

93378:I6G97 RS16225
gene id: 93378:I6G97_RS16225
uniprot id: A0A376D9U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

93378:I6G97 RS04545
gene id: 93378:I6G97_RS04545
uniprot id: A0A376DNH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsP family.
messages: Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress.
messages: Periplasm

93378:I6G97 RS07380
gene id: 93378:I6G97_RS07380
uniprot id: A0A376DKX4
names: Subcellular Location Annotation
messages: Cytoplasm

93378:I6G97 RS01120
gene id: 93378:I6G97_RS01120
uniprot id: A0A376D7Z3
names: Similarity
messages: Belongs to the rubredoxin family.

93378:I6G97 RS01065
gene id: 93378:I6G97_RS01065
uniprot id: A0A376D8L5
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

93378:I6G97 RS15885
gene id: 93378:I6G97_RS15885
uniprot id: A0A376DBB1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

93378:I6G97 RS03680
gene id: 93378:I6G97_RS03680
uniprot id: A0A376DNC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm
messages: Homodimer.

93378:I6G97 RS10335
gene id: 93378:I6G97_RS10335
uniprot id: A0A376DI08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

93378:I6G97 RS06555
gene id: 93378:I6G97_RS06555
uniprot id: A0A376DKQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

93378:I6G97 RS15985
gene id: 93378:I6G97_RS15985
uniprot id: A0A376DA13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

93378:I6G97 RS02255
gene id: 93378:I6G97_RS02255
uniprot id: A0A376D6M4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Monomer.

93378:I6G97 RS04420
gene id: 93378:I6G97_RS04420
uniprot id: A0A376DMP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

93378:I6G97 RS12005
gene id: 93378:I6G97_RS12005
uniprot id: A0A376DH33
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thioesterase PaaI family.
messages: Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA).
messages: Homotetramer. Dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS03735
gene id: 93378:I6G97_RS03735
uniprot id: A0A376DP90
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class B bacterial acid phosphatase family.
messages: Homotetramer.
messages: Periplasm

93378:I6G97 RS07015
gene id: 93378:I6G97_RS07015
uniprot id: A0A376DK63
names: Similarity
messages: Belongs to the SIS family. AgaS subfamily.

93378:I6G97 RS01775
gene id: 93378:I6G97_RS01775
uniprot id: A0A376D6I1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

93378:I6G97 RS16360
gene id: 93378:I6G97_RS16360
uniprot id: A0A376D9D2
names: Similarity
messages: Belongs to the NadC/ModD family.

93378:I6G97 RS09275
gene id: 93378:I6G97_RS09275
uniprot id: A0A376DHY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

93378:I6G97 RS08785
gene id: 93378:I6G97_RS08785
uniprot id: A0A376DK90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

93378:I6G97 RS04405
gene id: 93378:I6G97_RS04405
uniprot id: A0A376DMK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

93378:I6G97 RS11375
gene id: 93378:I6G97_RS11375
uniprot id: A0A376DFC2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS14640
gene id: 93378:I6G97_RS14640
uniprot id: A0A376DC58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

93378:I6G97 RS14060
gene id: 93378:I6G97_RS14060
uniprot id: A0A376DEG7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

93378:I6G97 RS08220
gene id: 93378:I6G97_RS08220
uniprot id: A0A376DJ07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

93378:I6G97 RS07995
gene id: 93378:I6G97_RS07995
uniprot id: A0A376DJ94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell inner membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

93378:I6G97 RS16345
gene id: 93378:I6G97_RS16345
uniprot id: A0A376D9Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'GDXG' lipolytic enzyme family.
messages: Cytoplasm
messages: Displays esterase activity towards short chain fatty esters (acyl chain length of up to 8 carbons). Able to hydrolyze triacetylglycerol (triacetin) and tributyrylglycerol (tributyrin), but not trioleylglycerol (triolein) or cholesterol oleate. Negatively regulates MalT activity by antagonizing maltotriose binding. Inhibits MelA galactosidase activity.
messages: Homodimer. Interacts with MalT and MelA.

93378:I6G97 RS13920
gene id: 93378:I6G97_RS13920
uniprot id: A0A376DCK7
names: Function
names: Similarity
messages: Belongs to the FliK family.
messages: Controls the length of the flagellar hook.

93378:I6G97 RS00875
gene id: 93378:I6G97_RS00875
uniprot id: A0A376D9S6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

93378:I6G97 RS16615
gene id: 93378:I6G97_RS16615
uniprot id: A0A376D935
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

93378:I6G97 RS08135
gene id: 93378:I6G97_RS08135
uniprot id: A0A376DIW8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

93378:I6G97 RS13140
gene id: 93378:I6G97_RS13140
uniprot id: A0A376DDW8
names: Function
names: Similarity
messages: Belongs to the CbiK family.
messages: Catalyzes the insertion of Co(2+) into sirohydrochlorin.

93378:I6G97 RS06820
gene id: 93378:I6G97_RS06820
uniprot id: A0A376DMC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

93378:I6G97 RS13185
gene id: 93378:I6G97_RS13185
uniprot id: A0A376DET4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93378:I6G97 RS14465
gene id: 93378:I6G97_RS14465
uniprot id: A0A376DCT4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Equilibrium between an active dimeric form, an inactive hexameric form and higher aggregates. Interconversion between the various forms is largely reversible and is influenced by the natural substrates and inhibitors of the enzyme.
messages: Feedback inhibited by histidine.

93378:I6G97 RS15155
gene id: 93378:I6G97_RS15155
uniprot id: A0A376DAZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

93378:I6G97 RS15980
gene id: 93378:I6G97_RS15980
uniprot id: A0A376DAW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

93378:I6G97 RS03485
gene id: 93378:I6G97_RS03485
uniprot id: A0A376DNH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

93378:I6G97 RS05660
gene id: 93378:I6G97_RS05660
uniprot id: A0A376DMX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Membrane

93378:I6G97 RS15765
gene id: 93378:I6G97_RS15765
uniprot id: A0A376D9X7
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 zinc ion per subunit.

93378:I6G97 RS14795
gene id: 93378:I6G97_RS14795
uniprot id: A0A376DBD1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

93378:I6G97 RS16175
gene id: 93378:I6G97_RS16175
uniprot id: A0A376D9W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS05400
gene id: 93378:I6G97_RS05400
uniprot id: A0A376DNP9
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

93378:I6G97 RS02325
gene id: 93378:I6G97_RS02325
uniprot id: A0A376D5Y2
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

93378:I6G97 RS01885
gene id: 93378:I6G97_RS01885
uniprot id: A0A376D6F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

93378:I6G97 RS14245
gene id: 93378:I6G97_RS14245
uniprot id: A0A376DCA4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

93378:I6G97 RS07890
gene id: 93378:I6G97_RS07890
uniprot id: A0A376DKK5
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

93378:I6G97 RS05430
gene id: 93378:I6G97_RS05430
uniprot id: A0A376DLU4
names: Subcellular Location Annotation
messages: Cell inner membrane

93378:I6G97 RS03690
gene id: 93378:I6G97_RS03690
uniprot id: A0A376DN70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

93378:I6G97 RS03110
gene id: 93378:I6G97_RS03110
uniprot id: A0A376D5A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

93378:I6G97 RS01905
gene id: 93378:I6G97_RS01905
uniprot id: A0A376D711
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

93378:I6G97 RS06505
gene id: 93378:I6G97_RS06505
uniprot id: A0A376DKP2
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

93378:I6G97 RS16050
gene id: 93378:I6G97_RS16050
uniprot id: A0A376DB57
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

93378:I6G97 RS14470
gene id: 93378:I6G97_RS14470
uniprot id: A0A376DC07
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Homodimer.

93378:I6G97 RS02515
gene id: 93378:I6G97_RS02515
uniprot id: A0A376D618
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

93378:I6G97 RS01860
gene id: 93378:I6G97_RS01860
uniprot id: A0A376D6F7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

93378:I6G97 RS01660
gene id: 93378:I6G97_RS01660
uniprot id: A0A376D6M1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

93378:I6G97 RS01145
gene id: 93378:I6G97_RS01145
uniprot id: A0A376D7X9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

93378:I6G97 RS09390
gene id: 93378:I6G97_RS09390
uniprot id: A0A376DHK5
names: Similarity
messages: Belongs to the peptidase M1 family.

93378:I6G97 RS07795
gene id: 93378:I6G97_RS07795
uniprot id: A0A376DLC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases.
messages: Periplasm
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

93378:I6G97 RS12965
gene id: 93378:I6G97_RS12965
uniprot id: A0A376DEV0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. PhnX family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Involved in phosphonate degradation.

93378:I6G97 RS06225
gene id: 93378:I6G97_RS06225
uniprot id: A0A376DL80
names: Similarity
messages: Belongs to the peptidase S1C family.

93378:I6G97 RS06935
gene id: 93378:I6G97_RS06935
uniprot id: A0A376DLF0
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

93378:I6G97 RS17015
gene id: 93378:I6G97_RS17015
uniprot id: A0A376DB13
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

93378:I6G97 RS03070
gene id: 93378:I6G97_RS03070
uniprot id: A0A376D5X2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily.
messages: Cell inner membrane
messages: Divalent metal cation transporter which exports Zn(2+), Cd(2+) and possibly Fe(2+). May be involved in zinc and iron detoxification by efflux.
messages: Homodimer.
messages: Membrane

93378:I6G97 RS05685
gene id: 93378:I6G97_RS05685
uniprot id: A0A376DMW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmG family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.

93378:I6G97 RS00945
gene id: 93378:I6G97_RS00945
uniprot id: A0A376D7T9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

93378:I6G97 RS02500
gene id: 93378:I6G97_RS02500
uniprot id: A0A376D5S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

93378:I6G97 RS08885
gene id: 93378:I6G97_RS08885
uniprot id: A0A376DI82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

93378:I6G97 RS12855
gene id: 93378:I6G97_RS12855
uniprot id: A0A376DDY6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

93378:I6G97 RS05330
gene id: 93378:I6G97_RS05330
uniprot id: A0A376DLX5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

93378:I6G97 RS08585
gene id: 93378:I6G97_RS08585
uniprot id: A0A376DIL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

93378:I6G97 RS02765
gene id: 93378:I6G97_RS02765
uniprot id: A0A376D5D2
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

93378:I6G97 RS04385
gene id: 93378:I6G97_RS04385
uniprot id: A0A1D8MUN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

93378:I6G97 RS04435
gene id: 93378:I6G97_RS04435
uniprot id: A0A376DMN9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Divalent metal cations. Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing. Has preference for mRNAs with a 5'-end purine. Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.

93378:I6G97 RS04830
gene id: 93378:I6G97_RS04830
uniprot id: A0A376DLT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.

93378:I6G97 RS01415
gene id: 93378:I6G97_RS01415
uniprot id: A0A376D6P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

93378:I6G97 RS09450
gene id: 93378:I6G97_RS09450
uniprot id: A0A376DHS3
names: Similarity
messages: Belongs to the UPF0757 family.

93378:I6G97 RS13835
gene id: 93378:I6G97_RS13835
uniprot id: A0A376DCU4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

93378:I6G97 RS06090
gene id: 93378:I6G97_RS06090
uniprot id: A0A376DLD9
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

93378:I6G97 RS14100
gene id: 93378:I6G97_RS14100
uniprot id: A0A376DC69
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

93378:I6G97 RS05140
gene id: 93378:I6G97_RS05140
uniprot id: A0A376DNA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FrdC family.
messages: Cell membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.

93378:I6G97 RS10490
gene id: 93378:I6G97_RS10490
uniprot id: A0A376DGL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
messages: Homodimer.

93378:I6G97 RS16705
gene id: 93378:I6G97_RS16705
uniprot id: A0A376D9E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

93378:I6G97 RS06005
gene id: 93378:I6G97_RS06005
uniprot id: A0A376DLX9
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

93378:I6G97 RS16600
gene id: 93378:I6G97_RS16600
uniprot id: A0A376D945
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS06705
gene id: 93378:I6G97_RS06705
uniprot id: A0A376DLX1
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

93378:I6G97 RS09570
gene id: 93378:I6G97_RS09570
uniprot id: A0A376DJI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Interacts with the TusBCD complex. Interacts with MnmA.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Could accept sulfur from TusD.

93378:I6G97 RS13175
gene id: 93378:I6G97_RS13175
uniprot id: A0A376DED0
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

93378:I6G97 RS05060
gene id: 93378:I6G97_RS05060
uniprot id: A0A376DM00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CutA family.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in resistance toward heavy metals.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS14625
gene id: 93378:I6G97_RS14625
uniprot id: A0A376DCL2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

93378:I6G97 RS02490
gene id: 93378:I6G97_RS02490
uniprot id: A0A376D5T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

93378:I6G97 RS17300
gene id: 93378:I6G97_RS17300
uniprot id: A0A376D8T1
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

93378:I6G97 RS01760
gene id: 93378:I6G97_RS01760
uniprot id: A0A376D7T6
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

93378:I6G97 RS04180
gene id: 93378:I6G97_RS04180
uniprot id: A0A376DMR1
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

93378:I6G97 RS05300
gene id: 93378:I6G97_RS05300
uniprot id: A0A376DLY6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

93378:I6G97 RS03750
gene id: 93378:I6G97_RS03750
uniprot id: A0A376DN49
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

93378:I6G97 RS15935
gene id: 93378:I6G97_RS15935
uniprot id: A0A376DB94
names: Similarity
messages: Belongs to the autoinducer synthase family.

93378:I6G97 RS06910
gene id: 93378:I6G97_RS06910
uniprot id: A0A376DKA3
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS05510
gene id: 93378:I6G97_RS05510
uniprot id: A0A376DLK3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

93378:I6G97 RS02130
gene id: 93378:I6G97_RS02130
uniprot id: A0A376D716
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TsgA family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

93378:I6G97 RS01365
gene id: 93378:I6G97_RS01365
uniprot id: A0A376D713
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

93378:I6G97 RS01000
gene id: 93378:I6G97_RS01000
uniprot id: A0A376D7I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

93378:I6G97 RS05440
gene id: 93378:I6G97_RS05440
uniprot id: A0A376DNN9
names: Similarity
messages: Belongs to the peptidase S13 family.

93378:I6G97 RS09470
gene id: 93378:I6G97_RS09470
uniprot id: A0A376DHQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

93378:I6G97 RS11360
gene id: 93378:I6G97_RS11360
uniprot id: A0A376DGS2
names: Similarity
messages: Belongs to the fructosamine kinase family.

93378:I6G97 RS08830
gene id: 93378:I6G97_RS08830
uniprot id: A0A376DID5
names: Similarity
messages: Belongs to the UPF0178 family.

93378:I6G97 RS06685
gene id: 93378:I6G97_RS06685
uniprot id: A0A376DK69
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

93378:I6G97 RS02420
gene id: 93378:I6G97_RS02420
uniprot id: A0A376D5L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93378:I6G97 RS11455
gene id: 93378:I6G97_RS11455
uniprot id: A0A376DFM7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

93378:I6G97 RS03450
gene id: 93378:I6G97_RS03450
uniprot id: A0A376DP42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

93378:I6G97 RS17465
gene id: 93378:I6G97_RS17465
uniprot id: A0A376DAL0
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

93378:I6G97 RS15620
gene id: 93378:I6G97_RS15620
uniprot id: A0A376DA49
names: Similarity
messages: Belongs to the SIS family. AgaS subfamily.

93378:I6G97 RS04910
gene id: 93378:I6G97_RS04910
uniprot id: A0A376DM22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

93378:I6G97 RS11795
gene id: 93378:I6G97_RS11795
uniprot id: A0A376DFY2
names: Similarity
messages: Belongs to the CFA/CMAS family.

93378:I6G97 RS02575
gene id: 93378:I6G97_RS02575
uniprot id: A0A376D6V3
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

93378:I6G97 RS14855
gene id: 93378:I6G97_RS14855
uniprot id: A0A376DBI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Membrane

93378:I6G97 RS17185
gene id: 93378:I6G97_RS17185
uniprot id: A0A376D965
names: Similarity
messages: Belongs to the YeeT/YkfH/YpjJ family.

93378:I6G97 RS11565
gene id: 93378:I6G97_RS11565
uniprot id: A0A376DFF0
names: Function
names: Similarity
messages: Belongs to the thiamine kinase family.
messages: Catalyzes the phosphorylation of thiamine to thiamine phosphate.

93378:I6G97 RS01950
gene id: 93378:I6G97_RS01950
uniprot id: A0A376D6B8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

93378:I6G97 RS09045
gene id: 93378:I6G97_RS09045
uniprot id: A0A376DK33
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.
messages: Homotetramer.

93378:I6G97 RS06805
gene id: 93378:I6G97_RS06805
uniprot id: A0A376DL30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

93378:I6G97 RS13825
gene id: 93378:I6G97_RS13825
uniprot id: A0A376DEQ2
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

93378:I6G97 RS08705
gene id: 93378:I6G97_RS08705
uniprot id: A0A376DJM6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

93378:I6G97 RS09110
gene id: 93378:I6G97_RS09110
uniprot id: A0A376DI02
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93378:I6G97 RS10305
gene id: 93378:I6G97_RS10305
uniprot id: A0A376DIR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

93378:I6G97 RS04115
gene id: 93378:I6G97_RS04115
uniprot id: A0A376DMG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

93378:I6G97 RS11545
gene id: 93378:I6G97_RS11545
uniprot id: A0A376DGR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

93378:I6G97 RS08575
gene id: 93378:I6G97_RS08575
uniprot id: A0A376DIC6
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

93378:I6G97 RS10925
gene id: 93378:I6G97_RS10925
uniprot id: A0A376DG71
names: Similarity
messages: Belongs to the peptidase S49 family.

93378:I6G97 RS15010
gene id: 93378:I6G97_RS15010
uniprot id: A0A376DBC5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

93378:I6G97 RS07515
gene id: 93378:I6G97_RS07515
uniprot id: A0A376DLN4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

93378:I6G97 RS02360
gene id: 93378:I6G97_RS02360
uniprot id: A0A376D6K8
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.

93378:I6G97 RS13940
gene id: 93378:I6G97_RS13940
uniprot id: A0A376DDD0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

93378:I6G97 RS16755
gene id: 93378:I6G97_RS16755
uniprot id: A0A376D9M1
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS03480
gene id: 93378:I6G97_RS03480
uniprot id: A0A376DPI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the low-affinity transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

93378:I6G97 RS12305
gene id: 93378:I6G97_RS12305
uniprot id: A0A376DFB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

93378:I6G97 RS03370
gene id: 93378:I6G97_RS03370
uniprot id: A0A376DP77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS16655
gene id: 93378:I6G97_RS16655
uniprot id: A0A376D9E0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

93378:I6G97 RS06195
gene id: 93378:I6G97_RS06195
uniprot id: A0A376DKS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

93378:I6G97 RS09195
gene id: 93378:I6G97_RS09195
uniprot id: A0A376DHZ2
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

93378:I6G97 RS03380
gene id: 93378:I6G97_RS03380
uniprot id: A0A376DPX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

93378:I6G97 RS02140
gene id: 93378:I6G97_RS02140
uniprot id: A0A376D8A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

93378:I6G97 RS05665
gene id: 93378:I6G97_RS05665
uniprot id: A0A376DLG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

93378:I6G97 RS10935
gene id: 93378:I6G97_RS10935
uniprot id: A0A376DH69
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

93378:I6G97 RS04820
gene id: 93378:I6G97_RS04820
uniprot id: A0A376DNK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Catalyzes both the uptake and excretion of putrescine. The uptake of putrescine is dependent on the membrane potential and the excretion involves putrescine-ornithine antiporter activity.
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS09215
gene id: 93378:I6G97_RS09215
uniprot id: A0A376DJ03
names: Similarity
messages: Belongs to the UPF0265 family.

93378:I6G97 RS00800
gene id: 93378:I6G97_RS00800
uniprot id: A0A376D898
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

93378:I6G97 RS14785
gene id: 93378:I6G97_RS14785
uniprot id: A0A376DBL5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

93378:I6G97 RS04565
gene id: 93378:I6G97_RS04565
uniprot id: A0A376DMJ8
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS05785
gene id: 93378:I6G97_RS05785
uniprot id: A0A376DL21
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

93378:I6G97 RS05470
gene id: 93378:I6G97_RS05470
uniprot id: A0A376DNM8
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

93378:I6G97 RS04400
gene id: 93378:I6G97_RS04400
uniprot id: A0A376DMQ4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

93378:I6G97 RS03985
gene id: 93378:I6G97_RS03985
uniprot id: A0A376DN13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

93378:I6G97 RS01550
gene id: 93378:I6G97_RS01550
uniprot id: A0A376D6Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

93378:I6G97 RS14270
gene id: 93378:I6G97_RS14270
uniprot id: A0A376DC94
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

93378:I6G97 RS04440
gene id: 93378:I6G97_RS04440
uniprot id: A0A376DN76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS11130
gene id: 93378:I6G97_RS11130
uniprot id: A0A376DGM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

93378:I6G97 RS04360
gene id: 93378:I6G97_RS04360
uniprot id: A0A376DNM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

93378:I6G97 RS02600
gene id: 93378:I6G97_RS02600
uniprot id: A0A376D7T7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS16010
gene id: 93378:I6G97_RS16010
uniprot id: A0A376D9T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SeqA family.
messages: Cytoplasm
messages: Homodimer. Polymerizes to form helical filaments.
messages: Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.

93378:I6G97 RS10720
gene id: 93378:I6G97_RS10720
uniprot id: A0A376DID6
names: Similarity
messages: Belongs to the pyruvate kinase family.

93378:I6G97 RS04265
gene id: 93378:I6G97_RS04265
uniprot id: A0A376DMN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

93378:I6G97 RS13590
gene id: 93378:I6G97_RS13590
uniprot id: A0A376DCQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

93378:I6G97 RS08970
gene id: 93378:I6G97_RS08970
uniprot id: A0A376DI77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

93378:I6G97 RS10630
gene id: 93378:I6G97_RS10630
uniprot id: A0A376DGD1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS17535
gene id: 93378:I6G97_RS17535
uniprot id: A0A376D8L1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

93378:I6G97 RS08335
gene id: 93378:I6G97_RS08335
uniprot id: A0A376DJG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

93378:I6G97 RS04695
gene id: 93378:I6G97_RS04695
uniprot id: A0A376DMF8
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

93378:I6G97 RS07505
gene id: 93378:I6G97_RS07505
uniprot id: A0A376DKS8
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS16720
gene id: 93378:I6G97_RS16720
uniprot id: A0A376D982
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

93378:I6G97 RS16045
gene id: 93378:I6G97_RS16045
uniprot id: A0A376D9S7
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

93378:I6G97 RS03010
gene id: 93378:I6G97_RS03010
uniprot id: A0A376D603
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraA family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.
messages: Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB.

93378:I6G97 RS09595
gene id: 93378:I6G97_RS09595
uniprot id: A0A376DHH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Cell membrane

93378:I6G97 RS08745
gene id: 93378:I6G97_RS08745
uniprot id: A0A376DJ01
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

93378:I6G97 RS14370
gene id: 93378:I6G97_RS14370
uniprot id: A0A376DCF7
names: Similarity
names: Subunit
messages: Belongs to the glutaredoxin family.
messages: Monomer.

93378:I6G97 RS01910
gene id: 93378:I6G97_RS01910
uniprot id: A0A376D735
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

93378:I6G97 RS08360
gene id: 93378:I6G97_RS08360
uniprot id: A0A376DIV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

93378:I6G97 RS08525
gene id: 93378:I6G97_RS08525
uniprot id: A0A376DIE3
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

93378:I6G97 RS08640
gene id: 93378:I6G97_RS08640
uniprot id: A0A376DIJ5
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

93378:I6G97 RS06580
gene id: 93378:I6G97_RS06580
uniprot id: A0A376DKR0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

93378:I6G97 RS05150
gene id: 93378:I6G97_RS05150
uniprot id: A0A376DLX3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).

93378:I6G97 RS16275
gene id: 93378:I6G97_RS16275
uniprot id: A0A376DBU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family. RcnA subfamily.
messages: Cell membrane
messages: Efflux system for nickel and cobalt.
messages: Membrane

93378:I6G97 RS09505
gene id: 93378:I6G97_RS09505
uniprot id: A0A376DI80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MatP family.
messages: Cytoplasm
messages: Homodimer.
messages: Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.

93378:I6G97 RS14020
gene id: 93378:I6G97_RS14020
uniprot id: A0A376DDR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

93378:I6G97 RS02305
gene id: 93378:I6G97_RS02305
uniprot id: A0A376D760
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

93378:I6G97 RS16205
gene id: 93378:I6G97_RS16205
uniprot id: A0A376D9N5
names: Similarity
messages: Belongs to the DNA polymerase HolA subunit family.

93378:I6G97 RS13110
gene id: 93378:I6G97_RS13110
uniprot id: A0A376DDR3
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

93378:I6G97 RS16450
gene id: 93378:I6G97_RS16450
uniprot id: A0A376DA11
names: Similarity
messages: In the C-terminal section; belongs to the glutathionylspermidine synthase preATP-grasp family.

93378:I6G97 RS05070
gene id: 93378:I6G97_RS05070
uniprot id: A0A376DML9
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

93378:I6G97 RS13355
gene id: 93378:I6G97_RS13355
uniprot id: A0A376DDA9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

93378:I6G97 RS02555
gene id: 93378:I6G97_RS02555
uniprot id: A0A376D7V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

93378:I6G97 RS00310
gene id: 93378:I6G97_RS00310
uniprot id: A0A376D867
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS16260
gene id: 93378:I6G97_RS16260
uniprot id: A0A376DAM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TatA/E family. TatE subfamily.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA.

93378:I6G97 RS06525
gene id: 93378:I6G97_RS06525
uniprot id: A0A376DKC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS02290
gene id: 93378:I6G97_RS02290
uniprot id: A0A376D5Z2
names: Function
names: Similarity
messages: Belongs to the FeoC family.
messages: May function as a transcriptional regulator that controls feoABC expression.

93378:I6G97 RS10670
gene id: 93378:I6G97_RS10670
uniprot id: A0A376DG22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

93378:I6G97 RS01645
gene id: 93378:I6G97_RS01645
uniprot id: A0A376D703
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93378:I6G97 RS00970
gene id: 93378:I6G97_RS00970
uniprot id: A0A376D7S8
names: Function
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.
messages: Catalyzes the formation of putrescine from agmatine.

93378:I6G97 RS01275
gene id: 93378:I6G97_RS01275
uniprot id: A0A376D7G0
names: Function
names: Subunit
messages: Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins.
messages: Homodimer.

93378:I6G97 RS16935
gene id: 93378:I6G97_RS16935
uniprot id: A0A376D8U2
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

93378:I6G97 RS02775
gene id: 93378:I6G97_RS02775
uniprot id: A0A376D620
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose.
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS15255
gene id: 93378:I6G97_RS15255
uniprot id: A0A376DB00
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

93378:I6G97 RS07915
gene id: 93378:I6G97_RS07915
uniprot id: A0A376DKJ6
names: Similarity
messages: Belongs to the DapA family.

93378:I6G97 RS14155
gene id: 93378:I6G97_RS14155
uniprot id: A0A376DCF4
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

93378:I6G97 RS06835
gene id: 93378:I6G97_RS06835
uniprot id: A0A376DKC5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

93378:I6G97 RS03950
gene id: 93378:I6G97_RS03950
uniprot id: A0A376DMK6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS00860
gene id: 93378:I6G97_RS00860
uniprot id: A0A376D7P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS13680
gene id: 93378:I6G97_RS13680
uniprot id: A0A376DDM3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapA family.
messages: Cell inner membrane
messages: Involved in the assembly of lipopolysaccharide (LPS).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS10475
gene id: 93378:I6G97_RS10475
uniprot id: A0A376DGP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

93378:I6G97 RS04415
gene id: 93378:I6G97_RS04415
uniprot id: A0A376DMI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

93378:I6G97 RS07050
gene id: 93378:I6G97_RS07050
uniprot id: A0A376DLI5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

93378:I6G97 RS10755
gene id: 93378:I6G97_RS10755
uniprot id: A0A376DGI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtI subfamily.
messages: Catalyzes the excretion of spermidine.
messages: Cell membrane
messages: Forms a complex with MdtJ.
messages: Membrane

93378:I6G97 RS13765
gene id: 93378:I6G97_RS13765
uniprot id: A0A376DET6
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

93378:I6G97 RS08120
gene id: 93378:I6G97_RS08120
uniprot id: A0A376DJ45
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

93378:I6G97 RS01955
gene id: 93378:I6G97_RS01955
uniprot id: A0A376D7K5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

93378:I6G97 RS02870
gene id: 93378:I6G97_RS02870
uniprot id: A0A376D659
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm
messages: Homodimer.

93378:I6G97 RS17345
gene id: 93378:I6G97_RS17345
uniprot id: A0A376D914
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

93378:I6G97 RS06770
gene id: 93378:I6G97_RS06770
uniprot id: A0A376DK38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

93378:I6G97 RS02070
gene id: 93378:I6G97_RS02070
uniprot id: A0A376D670
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm
messages: Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE.

93378:I6G97 RS11990
gene id: 93378:I6G97_RS11990
uniprot id: A0A376DF31
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

93378:I6G97 RS10940
gene id: 93378:I6G97_RS10940
uniprot id: A0A376DG58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SelU family.
messages: Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
messages: Monomer.

93378:I6G97 RS15640
gene id: 93378:I6G97_RS15640
uniprot id: A0A376DAG3
names: Similarity
messages: Belongs to the peptidase S11 family.

93378:I6G97 RS14430
gene id: 93378:I6G97_RS14430
uniprot id: A0A376DC71
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

93378:I6G97 RS02605
gene id: 93378:I6G97_RS02605
uniprot id: A0A376D5E5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS09510
gene id: 93378:I6G97_RS09510
uniprot id: A0A376DHF5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer and homodimer.
messages: The extracellular loops are most variable in sequence, and in some bacteria confer sensitivity to phage and/or colicins.
messages: With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage.

93378:I6G97 RS14980
gene id: 93378:I6G97_RS14980
uniprot id: A0A376DCL4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

93378:I6G97 RS01390
gene id: 93378:I6G97_RS01390
uniprot id: A0A376D702
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

93378:I6G97 RS01770
gene id: 93378:I6G97_RS01770
uniprot id: A0A376D797
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

93378:I6G97 RS05985
gene id: 93378:I6G97_RS05985
uniprot id: A0A376DL97
names: Similarity
messages: Belongs to the UPF0111 family.

93378:I6G97 RS07025
gene id: 93378:I6G97_RS07025
uniprot id: A0A376DK62
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS06110
gene id: 93378:I6G97_RS06110
uniprot id: A0A376DMC4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

93378:I6G97 RS02335
gene id: 93378:I6G97_RS02335
uniprot id: A0A376D5X4
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by ATP and maltotriose, which are both required for DNA binding.
messages: Belongs to the MalT family.
messages: Monomer in solution. Oligomerizes to an active state in the presence of the positive effectors ATP and maltotriose.
messages: Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.

93378:I6G97 RS05115
gene id: 93378:I6G97_RS05115
uniprot id: A0A376DNX3
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

93378:I6G97 RS04090
gene id: 93378:I6G97_RS04090
uniprot id: A0A376DNH7
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

93378:I6G97 RS11100
gene id: 93378:I6G97_RS11100
uniprot id: A0A376DG06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

93378:I6G97 RS02055
gene id: 93378:I6G97_RS02055
uniprot id: A0A376D8F3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

93378:I6G97 RS08580
gene id: 93378:I6G97_RS08580
uniprot id: A0A376DJS1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

93378:I6G97 RS02090
gene id: 93378:I6G97_RS02090
uniprot id: A0A376D656
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

93378:I6G97 RS02205
gene id: 93378:I6G97_RS02205
uniprot id: A0A376D6Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

93378:I6G97 RS06420
gene id: 93378:I6G97_RS06420
uniprot id: A0A376DKS3
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

93378:I6G97 RS07165
gene id: 93378:I6G97_RS07165
uniprot id: A0A376DL53
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

93378:I6G97 RS17045
gene id: 93378:I6G97_RS17045
uniprot id: A0A376D921
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

93378:I6G97 RS03420
gene id: 93378:I6G97_RS03420
uniprot id: A0A376DNG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

93378:I6G97 RS17520
gene id: 93378:I6G97_RS17520
uniprot id: A0A376D8A6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

93378:I6G97 RS11860
gene id: 93378:I6G97_RS11860
uniprot id: A0A376DF74
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS02040
gene id: 93378:I6G97_RS02040
uniprot id: A0A1D8MUN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

93378:I6G97 RS16675
gene id: 93378:I6G97_RS16675
uniprot id: A0A376D944
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

93378:I6G97 RS14170
gene id: 93378:I6G97_RS14170
uniprot id: A0A376DDJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

93378:I6G97 RS07310
gene id: 93378:I6G97_RS07310
uniprot id: A0A376DK02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

93378:I6G97 RS08175
gene id: 93378:I6G97_RS08175
uniprot id: A0A376DJ39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS13180
gene id: 93378:I6G97_RS13180
uniprot id: A0A376DDL9
names: Similarity
messages: Belongs to the CobH/CbiC family.

93378:I6G97 RS12335
gene id: 93378:I6G97_RS12335
uniprot id: A0A376DEJ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

93378:I6G97 RS13865
gene id: 93378:I6G97_RS13865
uniprot id: A0A376DCN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

93378:I6G97 RS03305
gene id: 93378:I6G97_RS03305
uniprot id: A0A376DP98
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

93378:I6G97 RS12835
gene id: 93378:I6G97_RS12835
uniprot id: A0A376DF49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family. RcnA subfamily.
messages: Cell membrane
messages: Efflux system for nickel and cobalt.
messages: Membrane

93378:I6G97 RS03795
gene id: 93378:I6G97_RS03795
uniprot id: A0A376DN93
names: Similarity
messages: Belongs to the YicC/YloC family.

93378:I6G97 RS06470
gene id: 93378:I6G97_RS06470
uniprot id: A0A376DM67
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.

93378:I6G97 RS01555
gene id: 93378:I6G97_RS01555
uniprot id: A0A376D8Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

93378:I6G97 RS12940
gene id: 93378:I6G97_RS12940
uniprot id: A0A376DDV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93378:I6G97 RS12125
gene id: 93378:I6G97_RS12125
uniprot id: A0A376DEW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

93378:I6G97 RS15265
gene id: 93378:I6G97_RS15265
uniprot id: A0A376DAW2
names: Similarity
messages: Belongs to the UPF0115 family.

93378:I6G97 RS12330
gene id: 93378:I6G97_RS12330
uniprot id: A0A376DFA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

93378:I6G97 RS03230
gene id: 93378:I6G97_RS03230
uniprot id: A0A376D555
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

93378:I6G97 RS10865
gene id: 93378:I6G97_RS10865
uniprot id: A0A376DGA6
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS04630
gene id: 93378:I6G97_RS04630
uniprot id: A0A376DMH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

93378:I6G97 RS04515
gene id: 93378:I6G97_RS04515
uniprot id: A0A376DN57
names: Function
names: Similarity
names: Subunit
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.
messages: Homodimer.

93378:I6G97 RS01035
gene id: 93378:I6G97_RS01035
uniprot id: A0A376D7D5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

93378:I6G97 RS09090
gene id: 93378:I6G97_RS09090
uniprot id: A0A376DJ62
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

93378:I6G97 RS14775
gene id: 93378:I6G97_RS14775
uniprot id: A0A376DBE3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RcsB family.
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.
messages: Interacts with RcsD.
messages: Phosphorylated and activated by RcsD.

93378:I6G97 RS05495
gene id: 93378:I6G97_RS05495
uniprot id: A0A376DLK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

93378:I6G97 RS16535
gene id: 93378:I6G97_RS16535
uniprot id: A0A376DAQ8
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

93378:I6G97 RS14810
gene id: 93378:I6G97_RS14810
uniprot id: A0A376DCU3
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

93378:I6G97 RS09440
gene id: 93378:I6G97_RS09440
uniprot id: A0A376DIX9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

93378:I6G97 RS05625
gene id: 93378:I6G97_RS05625
uniprot id: A0A376DNH8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

93378:I6G97 RS07305
gene id: 93378:I6G97_RS07305
uniprot id: A0A376DL90
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

93378:I6G97 RS05965
gene id: 93378:I6G97_RS05965
uniprot id: A0A376DL93
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

93378:I6G97 RS05980
gene id: 93378:I6G97_RS05980
uniprot id: A0A376DNA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. Pit subfamily.
messages: Membrane

93378:I6G97 RS15915
gene id: 93378:I6G97_RS15915
uniprot id: A0A376DC49
names: Similarity
messages: Belongs to the citrate synthase family.

93378:I6G97 RS12165
gene id: 93378:I6G97_RS12165
uniprot id: A0A376DGU9
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

93378:I6G97 RS04495
gene id: 93378:I6G97_RS04495
uniprot id: A0A376DMM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

93378:I6G97 RS03980
gene id: 93378:I6G97_RS03980
uniprot id: A0A376DMW6
names: Function
names: Similarity
messages: Belongs to the GppA/Ppx family. GppA subfamily.
messages: Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.

93378:I6G97 RS13240
gene id: 93378:I6G97_RS13240
uniprot id: A0A376DDL4
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

93378:I6G97 RS15050
gene id: 93378:I6G97_RS15050
uniprot id: A0A376DB88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 5DNU family.
messages: Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
messages: Cytoplasm
messages: Homodimer.

93378:I6G97 RS12445
gene id: 93378:I6G97_RS12445
uniprot id: A0A376DGI1
names: Similarity
messages: Belongs to the CFA/CMAS family.

93378:I6G97 RS14830
gene id: 93378:I6G97_RS14830
uniprot id: A0A376DCT3
names: Similarity
messages: Belongs to the MoaD family.

93378:I6G97 RS01530
gene id: 93378:I6G97_RS01530
uniprot id: A0A376D6S0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

93378:I6G97 RS17360
gene id: 93378:I6G97_RS17360
uniprot id: A0A376D9D0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

93378:I6G97 RS03445
gene id: 93378:I6G97_RS03445
uniprot id: A0A376DNK0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

93378:I6G97 RS14205
gene id: 93378:I6G97_RS14205
uniprot id: A0A376DC12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

93378:I6G97 RS03935
gene id: 93378:I6G97_RS03935
uniprot id: A0A376DN25
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

93378:I6G97 RS02955
gene id: 93378:I6G97_RS02955
uniprot id: A0A376D595
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

93378:I6G97 RS14160
gene id: 93378:I6G97_RS14160
uniprot id: A0A376DDB1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS06025
gene id: 93378:I6G97_RS06025
uniprot id: A0A376DMP8
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS08165
gene id: 93378:I6G97_RS08165
uniprot id: A0A376DK96
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

93378:I6G97 RS00815
gene id: 93378:I6G97_RS00815
uniprot id: A0A376D7M6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

93378:I6G97 RS14305
gene id: 93378:I6G97_RS14305
uniprot id: A0A376DDF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

93378:I6G97 RS04540
gene id: 93378:I6G97_RS04540
uniprot id: A0A376DN45
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

93378:I6G97 RS09150
gene id: 93378:I6G97_RS09150
uniprot id: A0A376DJZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
messages: Membrane

93378:I6G97 RS10560
gene id: 93378:I6G97_RS10560
uniprot id: A0A376DH76
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS04875
gene id: 93378:I6G97_RS04875
uniprot id: A0A376DMS7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

93378:I6G97 RS07585
gene id: 93378:I6G97_RS07585
uniprot id: A0A376DJK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
messages: Cell membrane
messages: Homotetramer.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.

93378:I6G97 RS05275
gene id: 93378:I6G97_RS05275
uniprot id: A0A376DLZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

93378:I6G97 RS03320
gene id: 93378:I6G97_RS03320
uniprot id: A0A376DPZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

93378:I6G97 RS06530
gene id: 93378:I6G97_RS06530
uniprot id: A0A376DKV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

93378:I6G97 RS16420
gene id: 93378:I6G97_RS16420
uniprot id: A0A376DAU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the low-affinity transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

93378:I6G97 RS11140
gene id: 93378:I6G97_RS11140
uniprot id: A0A376DH57
names: Function
names: Similarity
messages: Belongs to the TrpC family.
messages: Belongs to the TrpF family.
messages: Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.
messages: In the C-terminal section; belongs to the TrpF family.
messages: In the N-terminal section; belongs to the TrpC family.

93378:I6G97 RS10505
gene id: 93378:I6G97_RS10505
uniprot id: A0A376DGN2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

93378:I6G97 RS12280
gene id: 93378:I6G97_RS12280
uniprot id: A0A376DEN3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.

93378:I6G97 RS10760
gene id: 93378:I6G97_RS10760
uniprot id: A0A376DGE6
names: Similarity
messages: Belongs to the RutC family.

93378:I6G97 RS09070
gene id: 93378:I6G97_RS09070
uniprot id: A0A376DI45
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

93378:I6G97 RS04775
gene id: 93378:I6G97_RS04775
uniprot id: A0A376DNL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

93378:I6G97 RS16585
gene id: 93378:I6G97_RS16585
uniprot id: A0A376D9H6
names: Similarity
messages: Belongs to the intimin/invasin family.

93378:I6G97 RS00650
gene id: 93378:I6G97_RS00650
uniprot id: A0A376D7V0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

93378:I6G97 RS16730
gene id: 93378:I6G97_RS16730
uniprot id: A0A376D8X2
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

93378:I6G97 RS12490
gene id: 93378:I6G97_RS12490
uniprot id: A0A376DEI4
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

93378:I6G97 RS13055
gene id: 93378:I6G97_RS13055
uniprot id: A0A376DDR0
names: Similarity
messages: Belongs to the carbamate kinase family.

93378:I6G97 RS16310
gene id: 93378:I6G97_RS16310
uniprot id: A0A376DBT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA.
messages: Cytoplasm
messages: Homotetramer.

93378:I6G97 RS14920
gene id: 93378:I6G97_RS14920
uniprot id: A0A376DBK2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

93378:I6G97 RS07340
gene id: 93378:I6G97_RS07340
uniprot id: A0A376DJI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

93378:I6G97 RS03685
gene id: 93378:I6G97_RS03685
uniprot id: A0A376DPL3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

93378:I6G97 RS16885
gene id: 93378:I6G97_RS16885
uniprot id: A0A376D9V7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

93378:I6G97 RS11390
gene id: 93378:I6G97_RS11390
uniprot id: A0A376DFL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93378:I6G97 RS15130
gene id: 93378:I6G97_RS15130
uniprot id: A0A376DBZ0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS16520
gene id: 93378:I6G97_RS16520
uniprot id: A0A376D9Q0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

93378:I6G97 RS00120
gene id: 93378:I6G97_RS00120
uniprot id: A0A376IYB3
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

93378:I6G97 RS13970
gene id: 93378:I6G97_RS13970
uniprot id: A0A376DCJ0
names: Similarity
messages: Belongs to the YkuD family.

93378:I6G97 RS01655
gene id: 93378:I6G97_RS01655
uniprot id: A0A376D7L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

93378:I6G97 RS12325
gene id: 93378:I6G97_RS12325
uniprot id: A0A376DEL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

93378:I6G97 RS06635
gene id: 93378:I6G97_RS06635
uniprot id: A0A376DLR4
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

93378:I6G97 RS14335
gene id: 93378:I6G97_RS14335
uniprot id: A0A376DC73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

93378:I6G97 RS11290
gene id: 93378:I6G97_RS11290
uniprot id: A0A376DGU3
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS11595
gene id: 93378:I6G97_RS11595
uniprot id: A0A376DFH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93378:I6G97 RS17460
gene id: 93378:I6G97_RS17460
uniprot id: A0A376D8G2
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS03945
gene id: 93378:I6G97_RS03945
uniprot id: A0A376DMX8
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

93378:I6G97 RS04230
gene id: 93378:I6G97_RS04230
uniprot id: A0A376DMU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

93378:I6G97 RS08060
gene id: 93378:I6G97_RS08060
uniprot id: A0A376DIZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

93378:I6G97 RS11005
gene id: 93378:I6G97_RS11005
uniprot id: A0A376DGR6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RssB family.
messages: Binds to RpoS.
messages: Phosphorylated. Phosphorylation stimulates the interaction with RpoS and, therefore, the proteolysis of RpoS.
messages: Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co-degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation.

93378:I6G97 RS06585
gene id: 93378:I6G97_RS06585
uniprot id: A0A376DM20
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

93378:I6G97 RS02670
gene id: 93378:I6G97_RS02670
uniprot id: A0A376D6E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cdh family.
messages: Membrane

93378:I6G97 RS09095
gene id: 93378:I6G97_RS09095
uniprot id: A0A376DI33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

93378:I6G97 RS12355
gene id: 93378:I6G97_RS12355
uniprot id: A0A376DF89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

93378:I6G97 RS01540
gene id: 93378:I6G97_RS01540
uniprot id: A0A376D6H6
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

93378:I6G97 RS01925
gene id: 93378:I6G97_RS01925
uniprot id: A0A376D6C9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

93378:I6G97 RS13305
gene id: 93378:I6G97_RS13305
uniprot id: A0A376DFD1
names: Function
names: Similarity
messages: Belongs to the CitG/MdcB family.
messages: Involved in the formation of 2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase.

93378:I6G97 RS04410
gene id: 93378:I6G97_RS04410
uniprot id: A0A376DNL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

93378:I6G97 RS08650
gene id: 93378:I6G97_RS08650
uniprot id: A0A376DJJ0
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

93378:I6G97 RS00365
gene id: 93378:I6G97_RS00365
uniprot id: A0A376DAE0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

93378:I6G97 RS12705
gene id: 93378:I6G97_RS12705
uniprot id: A0A376DF52
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS07405
gene id: 93378:I6G97_RS07405
uniprot id: A0A376DJS6
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

93378:I6G97 RS01130
gene id: 93378:I6G97_RS01130
uniprot id: A0A376D826
names: Similarity
messages: Belongs to the HupG/HyaE family.

93378:I6G97 RS09025
gene id: 93378:I6G97_RS09025
uniprot id: A0A376DI32
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

93378:I6G97 RS08755
gene id: 93378:I6G97_RS08755
uniprot id: A0A376DIE5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93378:I6G97 RS16665
gene id: 93378:I6G97_RS16665
uniprot id: A0A376D9R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

93378:I6G97 RS06360
gene id: 93378:I6G97_RS06360
uniprot id: A0A376DKV2
names: Similarity
messages: Belongs to the Smp family.

93378:I6G97 RS08105
gene id: 93378:I6G97_RS08105
uniprot id: A0A376DIZ2
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS01190
gene id: 93378:I6G97_RS01190
uniprot id: A0A376D8G5
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

93378:I6G97 RS06115
gene id: 93378:I6G97_RS06115
uniprot id: A0A376DLC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

93378:I6G97 RS13690
gene id: 93378:I6G97_RS13690
uniprot id: A0A376DDV3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: Homodimer.

93378:I6G97 RS12030
gene id: 93378:I6G97_RS12030
uniprot id: A0A376DEQ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.
messages: Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin.

93378:I6G97 RS07750
gene id: 93378:I6G97_RS07750
uniprot id: A0A376DKS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily.
messages: Cell inner membrane
messages: Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system).
messages: Membrane

93378:I6G97 RS05035
gene id: 93378:I6G97_RS05035
uniprot id: A0A376DLZ9
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS11025
gene id: 93378:I6G97_RS11025
uniprot id: A0A376DG35
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

93378:I6G97 RS14895
gene id: 93378:I6G97_RS14895
uniprot id: A0A376DBL3
names: Function
names: Similarity
messages: Belongs to the isochorismate synthase family.
messages: Catalyzes the conversion of chorismate to isochorismate.

93378:I6G97 RS00950
gene id: 93378:I6G97_RS00950
uniprot id: A0A376D897
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

93378:I6G97 RS10900
gene id: 93378:I6G97_RS10900
uniprot id: A0A376DI61
names: Function
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.

93378:I6G97 RS04280
gene id: 93378:I6G97_RS04280
uniprot id: A0A376DNP8
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

93378:I6G97 RS04015
gene id: 93378:I6G97_RS04015
uniprot id: A0A376DPW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily.
messages: Catalyzes the four-electron oxidation of UDP-N-acetyl-D-mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N-acetylmannosaminuronic acid (UDP-ManNAcA).
messages: Homodimer.

93378:I6G97 RS14195
gene id: 93378:I6G97_RS14195
uniprot id: A0A376DCC9
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS09555
gene id: 93378:I6G97_RS09555
uniprot id: A0A376DI59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HspQ family.
messages: Cytoplasm
messages: Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress.

93378:I6G97 RS11680
gene id: 93378:I6G97_RS11680
uniprot id: A0A376DFJ8
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS03845
gene id: 93378:I6G97_RS03845
uniprot id: A0A376DMY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

93378:I6G97 RS17510
gene id: 93378:I6G97_RS17510
uniprot id: A0A376D8M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

93378:I6G97 RS09325
gene id: 93378:I6G97_RS09325
uniprot id: A0A376DHW6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

93378:I6G97 RS07335
gene id: 93378:I6G97_RS07335
uniprot id: A0A376DJZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

93378:I6G97 RS14435
gene id: 93378:I6G97_RS14435
uniprot id: A0A376DD15
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

93378:I6G97 RS07145
gene id: 93378:I6G97_RS07145
uniprot id: A0A376DJQ0
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS14055
gene id: 93378:I6G97_RS14055
uniprot id: A0A376DCK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

93378:I6G97 RS08700
gene id: 93378:I6G97_RS08700
uniprot id: A0A376DI76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamC family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

93378:I6G97 RS16325
gene id: 93378:I6G97_RS16325
uniprot id: A0A376DAJ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of FixA and FixB.
messages: Required for anaerobic carnitine reduction. May bring reductant to CaiA.

93378:I6G97 RS13160
gene id: 93378:I6G97_RS13160
uniprot id: A0A376DEU6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

93378:I6G97 RS15540
gene id: 93378:I6G97_RS15540
uniprot id: A0A376DAK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I11 (ecotin) family.
messages: General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases.
messages: Homodimer.
messages: Periplasm

93378:I6G97 RS16140
gene id: 93378:I6G97_RS16140
uniprot id: A0A376D9X4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

93378:I6G97 RS15870
gene id: 93378:I6G97_RS15870
uniprot id: A0A376DAA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS01245
gene id: 93378:I6G97_RS01245
uniprot id: A0A376D746
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS14875
gene id: 93378:I6G97_RS14875
uniprot id: A0A376DC99
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

93378:I6G97 RS15780
gene id: 93378:I6G97_RS15780
uniprot id: A0A376DA74
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS05155
gene id: 93378:I6G97_RS05155
uniprot id: A0A376DLJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
messages: Homodimer.
messages: With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P.

93378:I6G97 RS02085
gene id: 93378:I6G97_RS02085
uniprot id: A0A376D737
names: Similarity
messages: Belongs to the SlyX family.

93378:I6G97 RS09490
gene id: 93378:I6G97_RS09490
uniprot id: A0A376DIV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribosome modulation factor family.
messages: Cytoplasm
messages: During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).

93378:I6G97 RS00855
gene id: 93378:I6G97_RS00855
uniprot id: A0A376D7B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

93378:I6G97 RS16695
gene id: 93378:I6G97_RS16695
uniprot id: A0A376DAG1
names: Function
messages: Acts as a radical domain for damaged PFL and possibly other radical proteins.

93378:I6G97 RS08875
gene id: 93378:I6G97_RS08875
uniprot id: A0A376DIV2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

93378:I6G97 RS13905
gene id: 93378:I6G97_RS13905
uniprot id: A0A376DCY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

93378:I6G97 RS04925
gene id: 93378:I6G97_RS04925
uniprot id: A0A376DM34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

93378:I6G97 RS02165
gene id: 93378:I6G97_RS02165
uniprot id: A0A376D899
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

93378:I6G97 RS07525
gene id: 93378:I6G97_RS07525
uniprot id: A0A376DJL4
names: Similarity
messages: Belongs to the YkuD family.

93378:I6G97 RS09140
gene id: 93378:I6G97_RS09140
uniprot id: A0A376DJ42
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS10825
gene id: 93378:I6G97_RS10825
uniprot id: A0A376DG60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

93378:I6G97 RS04730
gene id: 93378:I6G97_RS04730
uniprot id: A0A376DPA6
names: Similarity
messages: Belongs to the peptidase S33 family.

93378:I6G97 RS15570
gene id: 93378:I6G97_RS15570
uniprot id: A0A376DB77
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

93378:I6G97 RS00395
gene id: 93378:I6G97_RS00395
uniprot id: A0A376D7W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

93378:I6G97 RS15140
gene id: 93378:I6G97_RS15140
uniprot id: A0A376DBF3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedD family.
messages: Cell inner membrane
messages: Non-essential cell division protein that could be required for efficient cell constriction.
messages: The SPOR domain binds septal peptidoglycans and is required to target DedD to the septal ring.

93378:I6G97 RS05800
gene id: 93378:I6G97_RS05800
uniprot id: A0A376DM19
names: Similarity
messages: Belongs to the phage portal family. PBSX subfamily.

93378:I6G97 RS11715
gene id: 93378:I6G97_RS11715
uniprot id: A0A376DGD9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
messages: Belongs to the Lpp family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: cell wall

93378:I6G97 RS16060
gene id: 93378:I6G97_RS16060
uniprot id: A0A376D9M7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS16455
gene id: 93378:I6G97_RS16455
uniprot id: A0A376D9A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HdeB family.
messages: Periplasm
messages: Required for optimal acid stress protection, which is important for survival of enteric bacteria in the acidic environment of the host stomach. Exhibits a chaperone-like activity at acidic pH by preventing the aggregation of many different periplasmic proteins.

93378:I6G97 RS06690
gene id: 93378:I6G97_RS06690
uniprot id: A0A376DKH0
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

93378:I6G97 RS13360
gene id: 93378:I6G97_RS13360
uniprot id: A0A376DF86
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS09315
gene id: 93378:I6G97_RS09315
uniprot id: A0A376DHN9
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

93378:I6G97 RS10145
gene id: 93378:I6G97_RS10145
uniprot id: A0A376DGX0
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

93378:I6G97 RS16320
gene id: 93378:I6G97_RS16320
uniprot id: A0A376D9S0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Heterodimer of FixA and FixB.
messages: Required for anaerobic carnitine reduction. May bring reductant to CaiA.

93378:I6G97 RS13525
gene id: 93378:I6G97_RS13525
uniprot id: A0A376DD47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs.
messages: Cytoplasm
messages: Interacts with TusE.

93378:I6G97 RS08695
gene id: 93378:I6G97_RS08695
uniprot id: A0A376DJ19
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

93378:I6G97 RS09400
gene id: 93378:I6G97_RS09400
uniprot id: A0A376DHT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
messages: Membrane

93378:I6G97 RS13705
gene id: 93378:I6G97_RS13705
uniprot id: A0A376DEU7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

93378:I6G97 RS13665
gene id: 93378:I6G97_RS13665
uniprot id: A0A376DEV3
names: Similarity
messages: Belongs to the SUI1 family.

93378:I6G97 RS16975
gene id: 93378:I6G97_RS16975
uniprot id: A0A376D947
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

93378:I6G97 RS06175
gene id: 93378:I6G97_RS06175
uniprot id: A0A376DLB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

93378:I6G97 RS14570
gene id: 93378:I6G97_RS14570
uniprot id: A0A376DBN1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS13480
gene id: 93378:I6G97_RS13480
uniprot id: A0A376DDD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

93378:I6G97 RS05775
gene id: 93378:I6G97_RS05775
uniprot id: A0A376DLD4
names: Function
names: Similarity
messages: Belongs to the phage GPA family.
messages: Possible endonuclease which induces a single-strand cut and initiates DNA replication.

93378:I6G97 RS16930
gene id: 93378:I6G97_RS16930
uniprot id: A0A376D9T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

93378:I6G97 RS01005
gene id: 93378:I6G97_RS01005
uniprot id: A0A376D8D7
names: Similarity
messages: Belongs to the UPF0307 family.

93378:I6G97 RS10485
gene id: 93378:I6G97_RS10485
uniprot id: A0A376DHP3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

93378:I6G97 RS10875
gene id: 93378:I6G97_RS10875
uniprot id: A0A376DG46
names: Similarity
messages: Belongs to the UPF0229 family.

93378:I6G97 RS04995
gene id: 93378:I6G97_RS04995
uniprot id: A0A376DP25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TorD/DmsD family. TorD subfamily.
messages: Cytoplasm
messages: Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.

93378:I6G97 RS01165
gene id: 93378:I6G97_RS01165
uniprot id: A0A376D9G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Catalyzes both the uptake and excretion of putrescine. The uptake of putrescine is dependent on the membrane potential and the excretion involves putrescine-ornithine antiporter activity.
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS07375
gene id: 93378:I6G97_RS07375
uniprot id: A0A376DJT5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

93378:I6G97 RS08625
gene id: 93378:I6G97_RS08625
uniprot id: A0A376DIA9
names: Similarity
messages: Belongs to the GppA/Ppx family.

93378:I6G97 RS03890
gene id: 93378:I6G97_RS03890
uniprot id: A0A376DN09
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS02180
gene id: 93378:I6G97_RS02180
uniprot id: A0A376D6Z2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

93378:I6G97 RS12310
gene id: 93378:I6G97_RS12310
uniprot id: A0A376DEL0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

93378:I6G97 RS04660
gene id: 93378:I6G97_RS04660
uniprot id: A0A376DMC0
names: Function
messages: Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase.

93378:I6G97 RS06290
gene id: 93378:I6G97_RS06290
uniprot id: A0A376DKM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aryl sulfotransferase family.
messages: Catalyzes the transfer of sulfuryl groups between phenolic compounds.
messages: Periplasm

93378:I6G97 RS15890
gene id: 93378:I6G97_RS15890
uniprot id: A0A376DC61
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

93378:I6G97 RS11615
gene id: 93378:I6G97_RS11615
uniprot id: A0A376DGH6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS14150
gene id: 93378:I6G97_RS14150
uniprot id: A0A376DCN6
names: Function
messages: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

93378:I6G97 RS04635
gene id: 93378:I6G97_RS04635
uniprot id: A0A376DN11
names: Similarity
messages: Belongs to the CitG/MdcB family.

93378:I6G97 RS00865
gene id: 93378:I6G97_RS00865
uniprot id: A0A376D8J0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

93378:I6G97 RS13410
gene id: 93378:I6G97_RS13410
uniprot id: A0A376DD64
names: Subcellular Location Annotation
messages: Cytoplasm

93378:I6G97 RS12105
gene id: 93378:I6G97_RS12105
uniprot id: A0A376DEZ0
names: Subcellular Location Annotation
messages: Cell inner membrane

93378:I6G97 RS05555
gene id: 93378:I6G97_RS05555
uniprot id: A0A376DLR5
names: Function
names: Similarity
messages: Belongs to the UbiT family.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor.

93378:I6G97 RS08305
gene id: 93378:I6G97_RS08305
uniprot id: A0A376DIX2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93378:I6G97 RS06135
gene id: 93378:I6G97_RS06135
uniprot id: A0A376DMB4
names: Subcellular Location Annotation
messages: Cytoplasm

93378:I6G97 RS00360
gene id: 93378:I6G97_RS00360
uniprot id: A0A376D871
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

93378:I6G97 RS05085
gene id: 93378:I6G97_RS05085
uniprot id: A0A376DNY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

93378:I6G97 RS11370
gene id: 93378:I6G97_RS11370
uniprot id: A0A376DHP9
names: Similarity
messages: Belongs to the transglycosylase Slt family.

93378:I6G97 RS02230
gene id: 93378:I6G97_RS02230
uniprot id: A0A376D6A9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

93378:I6G97 RS11995
gene id: 93378:I6G97_RS11995
uniprot id: A0A376DG24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

93378:I6G97 RS13930
gene id: 93378:I6G97_RS13930
uniprot id: A0A376DCX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

93378:I6G97 RS12360
gene id: 93378:I6G97_RS12360
uniprot id: A0A376DEN8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS01355
gene id: 93378:I6G97_RS01355
uniprot id: A0A376D734
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

93378:I6G97 RS17500
gene id: 93378:I6G97_RS17500
uniprot id: A0A376DAK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

93378:I6G97 RS05610
gene id: 93378:I6G97_RS05610
uniprot id: A0A376DM74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MzrA family.
messages: Cell inner membrane
messages: Interacts with EnvZ.
messages: Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR.

93378:I6G97 RS13405
gene id: 93378:I6G97_RS13405
uniprot id: A0A376DDY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

93378:I6G97 RS07315
gene id: 93378:I6G97_RS07315
uniprot id: A0A376DK39
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS06905
gene id: 93378:I6G97_RS06905
uniprot id: A0A376DKZ7
names: Similarity
messages: Belongs to the GSP E family.

93378:I6G97 RS06680
gene id: 93378:I6G97_RS06680
uniprot id: A0A376DMI3
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

93378:I6G97 RS15000
gene id: 93378:I6G97_RS15000
uniprot id: A0A376DDA8
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

93378:I6G97 RS10340
gene id: 93378:I6G97_RS10340
uniprot id: A0A376DIQ9
names: Similarity
messages: Belongs to the MotB family.

93378:I6G97 RS07110
gene id: 93378:I6G97_RS07110
uniprot id: A0A376DLG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Membrane

93378:I6G97 RS09540
gene id: 93378:I6G97_RS09540
uniprot id: A0A376DIT3
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

93378:I6G97 RS06100
gene id: 93378:I6G97_RS06100
uniprot id: A0A376DKW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

93378:I6G97 RS04025
gene id: 93378:I6G97_RS04025
uniprot id: A0A376DN03
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

93378:I6G97 RS03605
gene id: 93378:I6G97_RS03605
uniprot id: A0A376DPP8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

93378:I6G97 RS05230
gene id: 93378:I6G97_RS05230
uniprot id: A0A376DLU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

93378:I6G97 RS05640
gene id: 93378:I6G97_RS05640
uniprot id: A0A376DLN0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

93378:I6G97 RS14990
gene id: 93378:I6G97_RS14990
uniprot id: A0A376DCJ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

93378:I6G97 RS10330
gene id: 93378:I6G97_RS10330
uniprot id: A0A376DGS7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhC family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.

93378:I6G97 RS15095
gene id: 93378:I6G97_RS15095
uniprot id: A0A376DBH1
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

93378:I6G97 RS13900
gene id: 93378:I6G97_RS13900
uniprot id: A0A376DCR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

93378:I6G97 RS06940
gene id: 93378:I6G97_RS06940
uniprot id: A0A376DKC8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 3 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

93378:I6G97 RS03295
gene id: 93378:I6G97_RS03295
uniprot id: A0A376D5F7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

93378:I6G97 RS02565
gene id: 93378:I6G97_RS02565
uniprot id: A0A376D5Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

93378:I6G97 RS04350
gene id: 93378:I6G97_RS04350
uniprot id: A0A376DM89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

93378:I6G97 RS07325
gene id: 93378:I6G97_RS07325
uniprot id: A0A376DJV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Homodimer.

93378:I6G97 RS05235
gene id: 93378:I6G97_RS05235
uniprot id: A0A376DM06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

93378:I6G97 RS10715
gene id: 93378:I6G97_RS10715
uniprot id: A0A376DHN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

93378:I6G97 RS06185
gene id: 93378:I6G97_RS06185
uniprot id: A0A376DL36
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS02540
gene id: 93378:I6G97_RS02540
uniprot id: A0A376D607
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS15685
gene id: 93378:I6G97_RS15685
uniprot id: A0A376DA27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

93378:I6G97 RS00910
gene id: 93378:I6G97_RS00910
uniprot id: A0A376D9R5
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

93378:I6G97 RS05265
gene id: 93378:I6G97_RS05265
uniprot id: A0A376DMW8
names: Cofactor
names: Function
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity.

93378:I6G97 RS04675
gene id: 93378:I6G97_RS04675
uniprot id: A0A376DMB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

93378:I6G97 RS16715
gene id: 93378:I6G97_RS16715
uniprot id: A0A376DA33
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

93378:I6G97 RS10520
gene id: 93378:I6G97_RS10520
uniprot id: A0A376DGG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

93378:I6G97 RS14175
gene id: 93378:I6G97_RS14175
uniprot id: A0A376DEB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

93378:I6G97 RS08095
gene id: 93378:I6G97_RS08095
uniprot id: A0A376DL03
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

93378:I6G97 RS05380
gene id: 93378:I6G97_RS05380
uniprot id: A0A376DLV8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS14560
gene id: 93378:I6G97_RS14560
uniprot id: A0A376DBY1
names: Similarity
messages: Belongs to the peptidase C40 family.

93378:I6G97 RS01370
gene id: 93378:I6G97_RS01370
uniprot id: A0A376D8A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93378:I6G97 RS16505
gene id: 93378:I6G97_RS16505
uniprot id: A0A376DAE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

93378:I6G97 RS01565
gene id: 93378:I6G97_RS01565
uniprot id: A0A376D6S5
names: Function
names: Similarity
names: Subunit
messages: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.
messages: Belongs to the transcriptional regulatory Fis family.
messages: Homodimer.

93378:I6G97 RS10860
gene id: 93378:I6G97_RS10860
uniprot id: A0A376DGE5
names: Similarity
messages: Belongs to the peptidase M18 family.

93378:I6G97 RS10370
gene id: 93378:I6G97_RS10370
uniprot id: A0A376DHZ7
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

93378:I6G97 RS12245
gene id: 93378:I6G97_RS12245
uniprot id: A0A376DGR5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS04755
gene id: 93378:I6G97_RS04755
uniprot id: A0A376DLV7
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS04665
gene id: 93378:I6G97_RS04665
uniprot id: A0A376DN02
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS16620
gene id: 93378:I6G97_RS16620
uniprot id: A0A376DA75
names: Subcellular Location Annotation
messages: Cell inner membrane

93378:I6G97 RS16280
gene id: 93378:I6G97_RS16280
uniprot id: A0A376D9G0
names: Similarity
messages: Belongs to the transglycosylase Slt family.

93378:I6G97 RS04260
gene id: 93378:I6G97_RS04260
uniprot id: A0A376DP18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

93378:I6G97 RS10420
gene id: 93378:I6G97_RS10420
uniprot id: A0A376DHR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
messages: Membrane

93378:I6G97 RS13890
gene id: 93378:I6G97_RS13890
uniprot id: A0A376DCS6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

93378:I6G97 RS16065
gene id: 93378:I6G97_RS16065
uniprot id: A0A376DA44
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

93378:I6G97 RS16900
gene id: 93378:I6G97_RS16900
uniprot id: A0A376D976
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

93378:I6G97 RS06060
gene id: 93378:I6G97_RS06060
uniprot id: A0A376DKX2
names: Function
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.

93378:I6G97 RS02215
gene id: 93378:I6G97_RS02215
uniprot id: A0A376D790
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IgaA family.
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS09355
gene id: 93378:I6G97_RS09355
uniprot id: A0A376DHX0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

93378:I6G97 RS13975
gene id: 93378:I6G97_RS13975
uniprot id: A0A376DDT7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family. MukB subfamily.
messages: Homodimerization via its hinge domain. Binds to DNA via its C-terminal region. Interacts, and probably forms a ternary complex, with MukE and MukF via its C-terminal region. The complex formation is stimulated by calcium or magnesium. Interacts with tubulin-related protein FtsZ.
messages: Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
messages: The hinge domain, which separates the large intramolecular coiled coil regions, allows the homodimerization, forming a V-shaped homodimer.
messages: nucleoid

93378:I6G97 RS08820
gene id: 93378:I6G97_RS08820
uniprot id: A0A376DK80
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

93378:I6G97 RS11095
gene id: 93378:I6G97_RS11095
uniprot id: A0A376DG65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

93378:I6G97 RS11980
gene id: 93378:I6G97_RS11980
uniprot id: A0A376DG42
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

93378:I6G97 RS02050
gene id: 93378:I6G97_RS02050
uniprot id: A0A376D686
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

93378:I6G97 RS12225
gene id: 93378:I6G97_RS12225
uniprot id: A0A376DEG6
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS01020
gene id: 93378:I6G97_RS01020
uniprot id: A0A376D748
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

93378:I6G97 RS14525
gene id: 93378:I6G97_RS14525
uniprot id: A0A376DD87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Membrane

93378:I6G97 RS11560
gene id: 93378:I6G97_RS11560
uniprot id: A0A376DG72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LpoB family.
messages: Cell outer membrane
messages: Interacts with PBP1b.
messages: Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b).

93378:I6G97 RS04050
gene id: 93378:I6G97_RS04050
uniprot id: A0A376DPV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WzyE family.
messages: Cell inner membrane
messages: Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units.
messages: Probably part of a complex composed of WzxE, WzyE and WzzE.

93378:I6G97 RS07135
gene id: 93378:I6G97_RS07135
uniprot id: A0A376DK56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

93378:I6G97 RS06605
gene id: 93378:I6G97_RS06605
uniprot id: A0A376DLR7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
messages: Homodimer.

93378:I6G97 RS05650
gene id: 93378:I6G97_RS05650
uniprot id: A0A376DML0
names: Similarity
messages: Belongs to the UxaA family.

93378:I6G97 RS03360
gene id: 93378:I6G97_RS03360
uniprot id: A0A376DN78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions.

93378:I6G97 RS03125
gene id: 93378:I6G97_RS03125
uniprot id: A0A376D521
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

93378:I6G97 RS04005
gene id: 93378:I6G97_RS04005
uniprot id: A0A376DN05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WzzB/Cld/Rol family.
messages: Cell inner membrane
messages: Membrane
messages: Modulates the polysaccharide chain length of enterobacterial common antigen (ECA).
messages: Probably part of a complex composed of WzxE, WzyE and WzzE.

93378:I6G97 RS12410
gene id: 93378:I6G97_RS12410
uniprot id: A0A376DEL2
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

93378:I6G97 RS16650
gene id: 93378:I6G97_RS16650
uniprot id: A0A376D9S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

93378:I6G97 RS00940
gene id: 93378:I6G97_RS00940
uniprot id: A0A376D861
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

93378:I6G97 RS10800
gene id: 93378:I6G97_RS10800
uniprot id: A0A376DG70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

93378:I6G97 RS14880
gene id: 93378:I6G97_RS14880
uniprot id: A0A376DBG8
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS16920
gene id: 93378:I6G97_RS16920
uniprot id: A0A376D9F7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-552 family.
messages: Binds 1 Ca(2+) ion per monomer.
messages: Binds 5 heme c groups covalently per monomer.
messages: Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process.
messages: Periplasm

93378:I6G97 RS05175
gene id: 93378:I6G97_RS05175
uniprot id: A0A376DMY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

93378:I6G97 RS04825
gene id: 93378:I6G97_RS04825
uniprot id: A0A376DM58
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Homotetramer.
messages: Transcriptional repressor of the nikABCDE operon. Is active in the presence of excessive concentrations of intracellular nickel.

93378:I6G97 RS04290
gene id: 93378:I6G97_RS04290
uniprot id: A0A376DP08
names: Similarity
messages: Belongs to the peptidase S51 family.

93378:I6G97 RS06890
gene id: 93378:I6G97_RS06890
uniprot id: A0A376DKD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

93378:I6G97 RS12665
gene id: 93378:I6G97_RS12665
uniprot id: A0A376DED2
names: Similarity
messages: Belongs to the PrpF family.

93378:I6G97 RS12905
gene id: 93378:I6G97_RS12905
uniprot id: A0A376DEM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides.
messages: Monomer.

93378:I6G97 RS07965
gene id: 93378:I6G97_RS07965
uniprot id: A0A376DKH6
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS05605
gene id: 93378:I6G97_RS05605
uniprot id: A0A376DLN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS06215
gene id: 93378:I6G97_RS06215
uniprot id: A0A376DL94
names: Similarity
messages: Belongs to the BolA/IbaG family.

93378:I6G97 RS04645
gene id: 93378:I6G97_RS04645
uniprot id: A0A376DMH8
names: Subcellular Location Annotation
messages: Cytoplasm

93378:I6G97 RS06670
gene id: 93378:I6G97_RS06670
uniprot id: A0A376DKI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

93378:I6G97 RS01945
gene id: 93378:I6G97_RS01945
uniprot id: A0A376D723
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

93378:I6G97 RS14040
gene id: 93378:I6G97_RS14040
uniprot id: A0A376DCL6
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

93378:I6G97 RS13580
gene id: 93378:I6G97_RS13580
uniprot id: A0A376DE72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

93378:I6G97 RS05465
gene id: 93378:I6G97_RS05465
uniprot id: A0A376DLT2
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

93378:I6G97 RS15555
gene id: 93378:I6G97_RS15555
uniprot id: A0A376DAF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

93378:I6G97 RS10415
gene id: 93378:I6G97_RS10415
uniprot id: A0A376DGR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

93378:I6G97 RS04855
gene id: 93378:I6G97_RS04855
uniprot id: A0A376DNI9
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

93378:I6G97 RS10830
gene id: 93378:I6G97_RS10830
uniprot id: A0A376DHJ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

93378:I6G97 RS13925
gene id: 93378:I6G97_RS13925
uniprot id: A0A376DDV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

93378:I6G97 RS00850
gene id: 93378:I6G97_RS00850
uniprot id: A0A376D879
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

93378:I6G97 RS03800
gene id: 93378:I6G97_RS03800
uniprot id: A0A376DQ45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

93378:I6G97 RS01185
gene id: 93378:I6G97_RS01185
uniprot id: A0A376D783
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS14680
gene id: 93378:I6G97_RS14680
uniprot id: A0A376DCR3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

93378:I6G97 RS04285
gene id: 93378:I6G97_RS04285
uniprot id: A0A376DML7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RfaH family.
messages: Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons. Once bound, RfaH suppresses pausing and inhibits Rho-dependent and intrinsic termination at a subset of sites. Termination signals are bypassed, which allows complete synthesis of long RNA chains.
messages: Interacts with both the nontemplate DNA and the RNA polymerase (RNAP).

93378:I6G97 RS11045
gene id: 93378:I6G97_RS11045
uniprot id: A0A376DG79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

93378:I6G97 RS07185
gene id: 93378:I6G97_RS07185
uniprot id: A0A376DJZ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: Homohexamer.

93378:I6G97 RS05390
gene id: 93378:I6G97_RS05390
uniprot id: A0A376DLP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

93378:I6G97 RS03375
gene id: 93378:I6G97_RS03375
uniprot id: A0A376DND5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

93378:I6G97 RS02665
gene id: 93378:I6G97_RS02665
uniprot id: A0A376D5K4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93378:I6G97 RS04915
gene id: 93378:I6G97_RS04915
uniprot id: A0A376DM90
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

93378:I6G97 RS09125
gene id: 93378:I6G97_RS09125
uniprot id: A0A376DK04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

93378:I6G97 RS03425
gene id: 93378:I6G97_RS03425
uniprot id: A0A376DPK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

93378:I6G97 RS03725
gene id: 93378:I6G97_RS03725
uniprot id: A0A376DMU9
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

93378:I6G97 RS04950
gene id: 93378:I6G97_RS04950
uniprot id: A0A376DM78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. FucU mutarotase subfamily.
messages: Cytoplasm
messages: Homodecamer.
messages: Involved in the anomeric conversion of L-fucose.

93378:I6G97 RS16560
gene id: 93378:I6G97_RS16560
uniprot id: A0A376D9X3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

93378:I6G97 RS03465
gene id: 93378:I6G97_RS03465
uniprot id: A0A376DND9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

93378:I6G97 RS06750
gene id: 93378:I6G97_RS06750
uniprot id: A0A376DKF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

93378:I6G97 RS14065
gene id: 93378:I6G97_RS14065
uniprot id: A0A376DCT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

93378:I6G97 RS03580
gene id: 93378:I6G97_RS03580
uniprot id: A0A376DQC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

93378:I6G97 RS05535
gene id: 93378:I6G97_RS05535
uniprot id: A0A376DLJ9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS14190
gene id: 93378:I6G97_RS14190
uniprot id: A0A376DD22
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS10315
gene id: 93378:I6G97_RS10315
uniprot id: A0A376DGU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

93378:I6G97 RS04255
gene id: 93378:I6G97_RS04255
uniprot id: A0A376DMM5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS03400
gene id: 93378:I6G97_RS03400
uniprot id: A0A376DNC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

93378:I6G97 RS12055
gene id: 93378:I6G97_RS12055
uniprot id: A0A376DF00
names: Function
names: Similarity
messages: Belongs to the GlgS family.
messages: Major determinant of cell surface composition. Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides.

93378:I6G97 RS01460
gene id: 93378:I6G97_RS01460
uniprot id: A0A376D6W0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

93378:I6G97 RS02435
gene id: 93378:I6G97_RS02435
uniprot id: A0A376D5S4
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

93378:I6G97 RS00105
gene id: 93378:I6G97_RS00105
uniprot id: A0A376J3D3
names: Similarity
messages: Belongs to the FrmR/RcnR family.

93378:I6G97 RS01495
gene id: 93378:I6G97_RS01495
uniprot id: A0A376D6J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

93378:I6G97 RS02745
gene id: 93378:I6G97_RS02745
uniprot id: A0A376D6L7
names: Similarity
messages: Belongs to the peptidase M16 family.

93378:I6G97 RS15005
gene id: 93378:I6G97_RS15005
uniprot id: A0A376DD94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 30 kDa subunit family.
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

93378:I6G97 RS05540
gene id: 93378:I6G97_RS05540
uniprot id: A0A376DLQ4
names: Similarity
messages: Belongs to the UPF0597 family.

93378:I6G97 RS07175
gene id: 93378:I6G97_RS07175
uniprot id: A0A376DM03
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

93378:I6G97 RS08480
gene id: 93378:I6G97_RS08480
uniprot id: A0A376DJW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinone-dependent D-lactate dehydrogenase family.
messages: Catalyzes the oxidation of D-lactate to pyruvate.
messages: Cell inner membrane

93378:I6G97 RS02445
gene id: 93378:I6G97_RS02445
uniprot id: A0A376D7Z9
names: Similarity
messages: Belongs to the CdaR family.

93378:I6G97 RS16680
gene id: 93378:I6G97_RS16680
uniprot id: A0A376D9Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell inner membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

93378:I6G97 RS13735
gene id: 93378:I6G97_RS13735
uniprot id: A0A376DEU5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

93378:I6G97 RS02125
gene id: 93378:I6G97_RS02125
uniprot id: A0A376D655
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

93378:I6G97 RS07355
gene id: 93378:I6G97_RS07355
uniprot id: A0A376DJY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-(hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

93378:I6G97 RS13800
gene id: 93378:I6G97_RS13800
uniprot id: A0A376DDZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

93378:I6G97 RS07250
gene id: 93378:I6G97_RS07250
uniprot id: A0A376DLB5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Xni family.
messages: Binds 1 K(+) per subunit. The potassium ion strongly increases the affinity for DNA.
messages: Binds 2 Mg(2+) per subunit. Only one magnesium ion has a direct interaction with the protein, the other interactions are indirect.
messages: Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.

93378:I6G97 RS03145
gene id: 93378:I6G97_RS03145
uniprot id: A0A376D654
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

93378:I6G97 RS07020
gene id: 93378:I6G97_RS07020
uniprot id: A0A376DLB3
names: Subcellular Location Annotation
messages: Cytoplasm

93378:I6G97 RS10675
gene id: 93378:I6G97_RS10675
uniprot id: A0A376DGF8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

93378:I6G97 RS14970
gene id: 93378:I6G97_RS14970
uniprot id: A0A376DB44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

93378:I6G97 RS05955
gene id: 93378:I6G97_RS05955
uniprot id: A0A376DLY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

93378:I6G97 RS07875
gene id: 93378:I6G97_RS07875
uniprot id: A0A376DJG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

93378:I6G97 RS15505
gene id: 93378:I6G97_RS15505
uniprot id: A0A376DAV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

93378:I6G97 RS02370
gene id: 93378:I6G97_RS02370
uniprot id: A0A376D5W4
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

93378:I6G97 RS06000
gene id: 93378:I6G97_RS06000
uniprot id: A0A376DL95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-lipid IV(A) to form a Kdo(2)-(acyl)-lipid IV(A).
messages: Cell inner membrane

93378:I6G97 RS14620
gene id: 93378:I6G97_RS14620
uniprot id: A0A376DBY2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93378:I6G97 RS05950
gene id: 93378:I6G97_RS05950
uniprot id: A0A376DLA2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

93378:I6G97 RS03415
gene id: 93378:I6G97_RS03415
uniprot id: A0A376DN54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

93378:I6G97 RS07760
gene id: 93378:I6G97_RS07760
uniprot id: A0A376DJL2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

93378:I6G97 RS13770
gene id: 93378:I6G97_RS13770
uniprot id: A0A376DD34
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

93378:I6G97 RS11040
gene id: 93378:I6G97_RS11040
uniprot id: A0A376DHA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

93378:I6G97 RS02020
gene id: 93378:I6G97_RS02020
uniprot id: A0A376D768
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

93378:I6G97 RS15760
gene id: 93378:I6G97_RS15760
uniprot id: A0A376DC95
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

93378:I6G97 RS03390
gene id: 93378:I6G97_RS03390
uniprot id: A0A376DNM2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

93378:I6G97 RS02295
gene id: 93378:I6G97_RS02295
uniprot id: A0A376D6U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

93378:I6G97 RS03820
gene id: 93378:I6G97_RS03820
uniprot id: A0A376DPH3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS14325
gene id: 93378:I6G97_RS14325
uniprot id: A0A376DCX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93378:I6G97 RS06575
gene id: 93378:I6G97_RS06575
uniprot id: A0A376DLR9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93378:I6G97 RS04505
gene id: 93378:I6G97_RS04505
uniprot id: A0A376DMH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP subfamily.
messages: Catalyzes the proton-dependent transport of glutamate and aspartate.
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS14215
gene id: 93378:I6G97_RS14215
uniprot id: A0A376DD18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

93378:I6G97 RS15825
gene id: 93378:I6G97_RS15825
uniprot id: A0A376DB25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

93378:I6G97 RS07140
gene id: 93378:I6G97_RS07140
uniprot id: A0A376DM14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

93378:I6G97 RS09310
gene id: 93378:I6G97_RS09310
uniprot id: A0A376DHT4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

93378:I6G97 RS07345
gene id: 93378:I6G97_RS07345
uniprot id: A0A376DJU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.

93378:I6G97 RS15670
gene id: 93378:I6G97_RS15670
uniprot id: A0A376DA07
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

93378:I6G97 RS00820
gene id: 93378:I6G97_RS00820
uniprot id: A0A376D9U8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD, in which XerC interacts with XerD via its C-terminal region, XerD interacts with XerC via its C-terminal region and so on.
messages: FtsK may regulate the catalytic switch between XerC and XerD in the heterotetrameric complex during the two steps of the recombination process.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerD specifically exchanges the bottom DNA strands.

93378:I6G97 RS05475
gene id: 93378:I6G97_RS05475
uniprot id: A0A376DLS3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93378:I6G97 RS02170
gene id: 93378:I6G97_RS02170
uniprot id: A0A376D5U4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DamX family.
messages: Cell inner membrane
messages: Non-essential cell division protein.
messages: The SPOR domain binds septal peptidoglycans and is required to target DamX to the septal ring.

93378:I6G97 RS13955
gene id: 93378:I6G97_RS13955
uniprot id: A0A376DCW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

93378:I6G97 RS07600
gene id: 93378:I6G97_RS07600
uniprot id: A0A376DJS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

93378:I6G97 RS15840
gene id: 93378:I6G97_RS15840
uniprot id: A0A376D9V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

93378:I6G97 RS08375
gene id: 93378:I6G97_RS08375
uniprot id: A0A376DJE0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

93378:I6G97 RS07285
gene id: 93378:I6G97_RS07285
uniprot id: A0A376DK52
names: Similarity
messages: Belongs to the UPF0325 family.

93378:I6G97 RS03705
gene id: 93378:I6G97_RS03705
uniprot id: A0A376DPA2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93378:I6G97 RS02150
gene id: 93378:I6G97_RS02150
uniprot id: A0A376D645
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

93378:I6G97 RS12290
gene id: 93378:I6G97_RS12290
uniprot id: A0A376DER4
names: Similarity
messages: Belongs to the Hha/YmoA/Cnu family.

93378:I6G97 RS12500
gene id: 93378:I6G97_RS12500
uniprot id: A0A376DEE1
names: Cofactor
messages: Binds 1 Ca(2+) ion per subunit.

93378:I6G97 RS06395
gene id: 93378:I6G97_RS06395
uniprot id: A0A376DLY4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

93378:I6G97 RS05615
gene id: 93378:I6G97_RS05615
uniprot id: A0A376DLG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

93378:I6G97 RS07245
gene id: 93378:I6G97_RS07245
uniprot id: A0A376DJY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

93378:I6G97 RS04555
gene id: 93378:I6G97_RS04555
uniprot id: A0A376DPG8
names: Similarity
messages: Belongs to the aspartokinase family.

93378:I6G97 RS06855
gene id: 93378:I6G97_RS06855
uniprot id: A0A376DMB6
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

93378:I6G97 RS00425
gene id: 93378:I6G97_RS00425
uniprot id: A0A376D831
names: Function
names: Similarity
messages: Belongs to the polysaccharide lyase 8 family.
messages: Broad-specificity glycosaminoglycan lyase.

93378:I6G97 RS06170
gene id: 93378:I6G97_RS06170
uniprot id: A0A376DL57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.
messages: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

93378:I6G97 RS08130
gene id: 93378:I6G97_RS08130
uniprot id: A0A376DJQ2
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

93378:I6G97 RS15015
gene id: 93378:I6G97_RS15015
uniprot id: A0A376DC46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

93378:I6G97 RS01195
gene id: 93378:I6G97_RS01195
uniprot id: A0A376D7W4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS13340
gene id: 93378:I6G97_RS13340
uniprot id: A0A376DE31
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS02245
gene id: 93378:I6G97_RS02245
uniprot id: A0A376D5Z9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multiheme cytochrome c family.
messages: Binds 8 heme c groups covalently per monomer.
messages: Exposure to oxygen reduces copper binding and leads to the formation of a disulfide bond between the two Cys residues that bind the copper ion.
messages: Periplasm
messages: Respiratory sulfite reductase that catalyzes the reduction of sulfite to sulfide in a single step, consuming six electrons in the process.

93378:I6G97 RS10360
gene id: 93378:I6G97_RS10360
uniprot id: A0A376DGL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS02655
gene id: 93378:I6G97_RS02655
uniprot id: A0A376D6R1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

93378:I6G97 RS01500
gene id: 93378:I6G97_RS01500
uniprot id: A0A376D7K7
names: Similarity
messages: Belongs to the MreC family.

93378:I6G97 RS16735
gene id: 93378:I6G97_RS16735
uniprot id: A0A376D9D6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

93378:I6G97 RS06810
gene id: 93378:I6G97_RS06810
uniprot id: A0A376DLJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

93378:I6G97 RS06640
gene id: 93378:I6G97_RS06640
uniprot id: A0A376DKJ5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

93378:I6G97 RS05960
gene id: 93378:I6G97_RS05960
uniprot id: A0A376DMF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
messages: Homooctamer.

93378:I6G97 RS03790
gene id: 93378:I6G97_RS03790
uniprot id: A0A376DP78
names: Similarity
messages: Belongs to the UPF0438 family.

93378:I6G97 RS04655
gene id: 93378:I6G97_RS04655
uniprot id: A0A376DLZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CitD family.
messages: Covalent carrier of the coenzyme of citrate lyase.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.

93378:I6G97 RS11600
gene id: 93378:I6G97_RS11600
uniprot id: A0A376DHH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

93378:I6G97 RS08225
gene id: 93378:I6G97_RS08225
uniprot id: A0A376DJ17
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

93378:I6G97 RS15865
gene id: 93378:I6G97_RS15865
uniprot id: A0A376DAI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

93378:I6G97 RS16030
gene id: 93378:I6G97_RS16030
uniprot id: A0A376DA54
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

93378:I6G97 RS15770
gene id: 93378:I6G97_RS15770
uniprot id: A0A376DA92
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS04320
gene id: 93378:I6G97_RS04320
uniprot id: A0A376DPL9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Belongs to the flavodoxin family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell membrane

93378:I6G97 RS07860
gene id: 93378:I6G97_RS07860
uniprot id: A0A376DJ74
names: Similarity
messages: Belongs to the nitroreductase family.

93378:I6G97 RS07300
gene id: 93378:I6G97_RS07300
uniprot id: A0A376DK03
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

93378:I6G97 RS16860
gene id: 93378:I6G97_RS16860
uniprot id: A0A376D952
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

93378:I6G97 RS03440
gene id: 93378:I6G97_RS03440
uniprot id: A0A376DNE9
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS17020
gene id: 93378:I6G97_RS17020
uniprot id: A0A376D8L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

93378:I6G97 RS03020
gene id: 93378:I6G97_RS03020
uniprot id: A0A376D5E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

93378:I6G97 RS06675
gene id: 93378:I6G97_RS06675
uniprot id: A0A376DKM9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

93378:I6G97 RS01070
gene id: 93378:I6G97_RS01070
uniprot id: A0A376D812
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

93378:I6G97 RS00835
gene id: 93378:I6G97_RS00835
uniprot id: A0A376D8K0
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

93378:I6G97 RS12590
gene id: 93378:I6G97_RS12590
uniprot id: A0A376DEX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

93378:I6G97 RS14720
gene id: 93378:I6G97_RS14720
uniprot id: A0A376DCG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

93378:I6G97 RS07415
gene id: 93378:I6G97_RS07415
uniprot id: A0A376DL49
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

93378:I6G97 RS01560
gene id: 93378:I6G97_RS01560
uniprot id: A0A376D6G4
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

93378:I6G97 RS04990
gene id: 93378:I6G97_RS04990
uniprot id: A0A376DM71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

93378:I6G97 RS03115
gene id: 93378:I6G97_RS03115
uniprot id: A0A376D510
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

93378:I6G97 RS01170
gene id: 93378:I6G97_RS01170
uniprot id: A0A376D6Z7
names: Similarity
messages: Belongs to the LacAB/RpiB family.

93378:I6G97 RS03285
gene id: 93378:I6G97_RS03285
uniprot id: A0A376D5G0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

93378:I6G97 RS00215
gene id: 93378:I6G97_RS00215
uniprot id: A0A376IY07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the relaxosome TraM family.
messages: Cytoplasm

93378:I6G97 RS16335
gene id: 93378:I6G97_RS16335
uniprot id: A0A376DBS7
names: Function
names: Similarity
messages: Belongs to the bacterial-type ferredoxin family. FixX subfamily.
messages: Could be a 3Fe-4S cluster-containing protein.

93378:I6G97 RS05225
gene id: 93378:I6G97_RS05225
uniprot id: A0A376DMX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

93378:I6G97 RS14080
gene id: 93378:I6G97_RS14080
uniprot id: A0A376DDG6
names: Similarity
messages: Belongs to the asparaginase 1 family.

93378:I6G97 RS09605
gene id: 93378:I6G97_RS09605
uniprot id: A0A376DH19
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
messages: Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

93378:I6G97 RS04840
gene id: 93378:I6G97_RS04840
uniprot id: A0A376DMT7
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

93378:I6G97 RS03035
gene id: 93378:I6G97_RS03035
uniprot id: A0A376D795
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS14945
gene id: 93378:I6G97_RS14945
uniprot id: A0A376DBJ2
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

93378:I6G97 RS14515
gene id: 93378:I6G97_RS14515
uniprot id: A0A376DC38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Set transporter family.
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS02080
gene id: 93378:I6G97_RS02080
uniprot id: A0A376D6H2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

93378:I6G97 RS07090
gene id: 93378:I6G97_RS07090
uniprot id: A0A376DKA8
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

93378:I6G97 RS08350
gene id: 93378:I6G97_RS08350
uniprot id: A0A376DIV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

93378:I6G97 RS04890
gene id: 93378:I6G97_RS04890
uniprot id: A0A376DM39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Monomer.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

93378:I6G97 RS14885
gene id: 93378:I6G97_RS14885
uniprot id: A0A376DCQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

93378:I6G97 RS04355
gene id: 93378:I6G97_RS04355
uniprot id: A0A376DML4
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

93378:I6G97 RS17545
gene id: 93378:I6G97_RS17545
uniprot id: A0A376D896
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

93378:I6G97 RS06140
gene id: 93378:I6G97_RS06140
uniprot id: A0A376DLB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RapZ-like family. RapZ subfamily.
messages: Homotrimer.
messages: Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.

93378:I6G97 RS02155
gene id: 93378:I6G97_RS02155
uniprot id: A0A376D705
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Monomer.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

93378:I6G97 RS01175
gene id: 93378:I6G97_RS01175
uniprot id: A0A376D7K1
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS07805
gene id: 93378:I6G97_RS07805
uniprot id: A0A376DJA7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS00895
gene id: 93378:I6G97_RS00895
uniprot id: A0A376D7I5
names: Similarity
messages: Belongs to the UPF0149 family.

93378:I6G97 RS07780
gene id: 93378:I6G97_RS07780
uniprot id: A0A376DJK1
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

93378:I6G97 RS11030
gene id: 93378:I6G97_RS11030
uniprot id: A0A376DGQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

93378:I6G97 RS08030
gene id: 93378:I6G97_RS08030
uniprot id: A0A376DJA1
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

93378:I6G97 RS07320
gene id: 93378:I6G97_RS07320
uniprot id: A0A376DKZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

93378:I6G97 RS04140
gene id: 93378:I6G97_RS04140
uniprot id: A0A376DMX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

93378:I6G97 RS01410
gene id: 93378:I6G97_RS01410
uniprot id: A0A376D883
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Membrane

93378:I6G97 RS03200
gene id: 93378:I6G97_RS03200
uniprot id: A0A376D728
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Interacts with IscS.
messages: Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.

93378:I6G97 RS11650
gene id: 93378:I6G97_RS11650
uniprot id: A0A376DGM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

93378:I6G97 RS11875
gene id: 93378:I6G97_RS11875
uniprot id: A0A376DF45
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

93378:I6G97 RS11080
gene id: 93378:I6G97_RS11080
uniprot id: A0A376DGN9
names: Similarity
messages: Belongs to the YciI family.

93378:I6G97 RS03830
gene id: 93378:I6G97_RS03830
uniprot id: A0A376DMR4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

93378:I6G97 RS13775
gene id: 93378:I6G97_RS13775
uniprot id: A0A376DCV8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

93378:I6G97 RS02825
gene id: 93378:I6G97_RS02825
uniprot id: A0A376D601
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

93378:I6G97 RS01755
gene id: 93378:I6G97_RS01755
uniprot id: A0A376D6J0
names: Similarity
messages: Belongs to the UPF0047 family.

93378:I6G97 RS02760
gene id: 93378:I6G97_RS02760
uniprot id: A0A376D642
names: Function
messages: Required for maximal bacterial cellulose synthesis.

93378:I6G97 RS07880
gene id: 93378:I6G97_RS07880
uniprot id: A0A376DJZ4
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

93378:I6G97 RS15145
gene id: 93378:I6G97_RS15145
uniprot id: A0A376DB51
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

93378:I6G97 RS11735
gene id: 93378:I6G97_RS11735
uniprot id: A0A376DFD7
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

93378:I6G97 RS06105
gene id: 93378:I6G97_RS06105
uniprot id: A0A376DL74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.
messages: The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.

93378:I6G97 RS13085
gene id: 93378:I6G97_RS13085
uniprot id: A0A376DEP3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93378:I6G97 RS02010
gene id: 93378:I6G97_RS02010
uniprot id: A0A376D608
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

93378:I6G97 RS15950
gene id: 93378:I6G97_RS15950
uniprot id: A0A376DA28
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

93378:I6G97 RS04030
gene id: 93378:I6G97_RS04030
uniprot id: A0A376DMW3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WecD family.
messages: Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino-4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS05635
gene id: 93378:I6G97_RS05635
uniprot id: A0A376DL60
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS01970
gene id: 93378:I6G97_RS01970
uniprot id: A0A376D793
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

93378:I6G97 RS08200
gene id: 93378:I6G97_RS08200
uniprot id: A0A376DJ28
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS15750
gene id: 93378:I6G97_RS15750
uniprot id: A0A376DA16
names: Similarity
messages: Belongs to the ModE family.

93378:I6G97 RS15790
gene id: 93378:I6G97_RS15790
uniprot id: A0A376D9W3
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

93378:I6G97 RS03590
gene id: 93378:I6G97_RS03590
uniprot id: A0A376DNB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

93378:I6G97 RS06965
gene id: 93378:I6G97_RS06965
uniprot id: A0A376DKC1
names: Similarity
messages: Belongs to the UPF0231 family.

93378:I6G97 RS11730
gene id: 93378:I6G97_RS11730
uniprot id: A0A376DEZ1
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

93378:I6G97 RS11745
gene id: 93378:I6G97_RS11745
uniprot id: A0A376DFC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS01430
gene id: 93378:I6G97_RS01430
uniprot id: A0A376D872
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers. Binds only one seryl-tRNA(Sec) per dimer.

93378:I6G97 RS12270
gene id: 93378:I6G97_RS12270
uniprot id: A0A376DFV9
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

93378:I6G97 RS07220
gene id: 93378:I6G97_RS07220
uniprot id: A0A376DLZ2
names: Similarity
messages: Belongs to the SufE family.

93378:I6G97 RS02065
gene id: 93378:I6G97_RS02065
uniprot id: A0A376D6X2
names: Similarity
messages: Belongs to the DsrF/TusC family.

93378:I6G97 RS15315
gene id: 93378:I6G97_RS15315
uniprot id: A0A376DBK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

93378:I6G97 RS04905
gene id: 93378:I6G97_RS04905
uniprot id: A0A376DMR6
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

93378:I6G97 RS02030
gene id: 93378:I6G97_RS02030
uniprot id: A0A376D8G3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

93378:I6G97 RS03920
gene id: 93378:I6G97_RS03920
uniprot id: A0A376DMZ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

93378:I6G97 RS03030
gene id: 93378:I6G97_RS03030
uniprot id: A0A376D529
names: Similarity
messages: Belongs to the FBPase class 2 family.

93378:I6G97 RS07370
gene id: 93378:I6G97_RS07370
uniprot id: A0A376DK20
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

93378:I6G97 RS02000
gene id: 93378:I6G97_RS02000
uniprot id: A0A376D6A6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

93378:I6G97 RS14450
gene id: 93378:I6G97_RS14450
uniprot id: A0A376DCD7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

93378:I6G97 RS04680
gene id: 93378:I6G97_RS04680
uniprot id: A0A376DMF7
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS01055
gene id: 93378:I6G97_RS01055
uniprot id: A0A376D858
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
messages: Membrane

93378:I6G97 RS06415
gene id: 93378:I6G97_RS06415
uniprot id: A0A376DLH8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

93378:I6G97 RS03505
gene id: 93378:I6G97_RS03505
uniprot id: A0A376DPH9
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

93378:I6G97 RS05940
gene id: 93378:I6G97_RS05940
uniprot id: A0A376DKZ1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

93378:I6G97 RS12370
gene id: 93378:I6G97_RS12370
uniprot id: A0A376DEA2
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

93378:I6G97 RS01095
gene id: 93378:I6G97_RS01095
uniprot id: A0A376D802
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93378:I6G97 RS01850
gene id: 93378:I6G97_RS01850
uniprot id: A0A376D687
names: Similarity
messages: Belongs to the Smg family.

93378:I6G97 RS08870
gene id: 93378:I6G97_RS08870
uniprot id: A0A376DI57
names: Subcellular Location Annotation
messages: Cytoplasm

93378:I6G97 RS02115
gene id: 93378:I6G97_RS02115
uniprot id: A0A376D8B5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in both the arginine and lysine biosynthetic pathways.

93378:I6G97 RS10705
gene id: 93378:I6G97_RS10705
uniprot id: A0A376DHG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M23B family.
messages: Membrane

93378:I6G97 RS17290
gene id: 93378:I6G97_RS17290
uniprot id: A0A376D9S8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery.

93378:I6G97 RS17375
gene id: 93378:I6G97_RS17375
uniprot id: A0A376DAN4
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS14965
gene id: 93378:I6G97_RS14965
uniprot id: A0A376DDF9
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS12170
gene id: 93378:I6G97_RS12170
uniprot id: A0A376DEI6
names: Similarity
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.

93378:I6G97 RS08435
gene id: 93378:I6G97_RS08435
uniprot id: A0A376DIR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

93378:I6G97 RS07055
gene id: 93378:I6G97_RS07055
uniprot id: A0A376DK78
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

93378:I6G97 RS08515
gene id: 93378:I6G97_RS08515
uniprot id: A0A376DIP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
messages: Membrane

93378:I6G97 RS14090
gene id: 93378:I6G97_RS14090
uniprot id: A0A376DDP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

93378:I6G97 RS08620
gene id: 93378:I6G97_RS08620
uniprot id: A0A376DJ46
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

93378:I6G97 RS09380
gene id: 93378:I6G97_RS09380
uniprot id: A0A376DHV7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

93378:I6G97 RS12575
gene id: 93378:I6G97_RS12575
uniprot id: A0A376DFF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PqiA family.
messages: Component of a transport pathway that contributes to membrane integrity.
messages: Membrane

93378:I6G97 RS06900
gene id: 93378:I6G97_RS06900
uniprot id: A0A376DKA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS16940
gene id: 93378:I6G97_RS16940
uniprot id: A0A376DA68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

93378:I6G97 RS14770
gene id: 93378:I6G97_RS14770
uniprot id: A0A376DDP1
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RcsD family.
messages: Cell inner membrane
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.
messages: Interacts with RcsC and RcsB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylated by RcsC.

93378:I6G97 RS07575
gene id: 93378:I6G97_RS07575
uniprot id: A0A376DJT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

93378:I6G97 RS12980
gene id: 93378:I6G97_RS12980
uniprot id: A0A376DDJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sialate:H(+) symporter (SHS) (TC 2.A.1.12) family.
messages: Catalyzes the proton-dependent transport of sialic acid.
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS10060
gene id: 93378:I6G97_RS10060
uniprot id: A0A376DH03
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

93378:I6G97 RS04625
gene id: 93378:I6G97_RS04625
uniprot id: A0A376DM08
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

93378:I6G97 RS15905
gene id: 93378:I6G97_RS15905
uniprot id: A0A376DAZ6
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

93378:I6G97 RS01135
gene id: 93378:I6G97_RS01135
uniprot id: A0A376D796
names: Similarity
messages: Belongs to the peptidase A31 family.

93378:I6G97 RS06120
gene id: 93378:I6G97_RS06120
uniprot id: A0A376DN73
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cytochrome b562 family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per molecule.
messages: Electron-transport protein of unknown function.

93378:I6G97 RS11415
gene id: 93378:I6G97_RS11415
uniprot id: A0A376DFK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GhoT/OrtT toxin family.
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS13645
gene id: 93378:I6G97_RS13645
uniprot id: A0A376DCN3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

93378:I6G97 RS01990
gene id: 93378:I6G97_RS01990
uniprot id: A0A376D6B3
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

93378:I6G97 RS08040
gene id: 93378:I6G97_RS08040
uniprot id: A0A376DJ08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

93378:I6G97 RS08775
gene id: 93378:I6G97_RS08775
uniprot id: A0A376DI49
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS03260
gene id: 93378:I6G97_RS03260
uniprot id: A0A376D5N9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

93378:I6G97 RS14510
gene id: 93378:I6G97_RS14510
uniprot id: A0A376DBQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Periplasm

93378:I6G97 RS14905
gene id: 93378:I6G97_RS14905
uniprot id: A0A376DBF7
names: Similarity
messages: Belongs to the peptidase C69 family.

93378:I6G97 RS03785
gene id: 93378:I6G97_RS03785
uniprot id: A0A376DN56
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93378:I6G97 RS02450
gene id: 93378:I6G97_RS02450
uniprot id: A0A376D6F5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

93378:I6G97 RS17280
gene id: 93378:I6G97_RS17280
uniprot id: A0A376D9E5
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

93378:I6G97 RS04135
gene id: 93378:I6G97_RS04135
uniprot id: A0A376DMQ9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

93378:I6G97 RS13700
gene id: 93378:I6G97_RS13700
uniprot id: A0A376DE27
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS05460
gene id: 93378:I6G97_RS05460
uniprot id: A0A376DLL9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS10750
gene id: 93378:I6G97_RS10750
uniprot id: A0A376DIC8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtJ subfamily.
messages: Catalyzes the excretion of spermidine.
messages: Cell membrane
messages: Forms a complex with MdtI.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93378:I6G97 RS15125
gene id: 93378:I6G97_RS15125
uniprot id: A0A376DBU5
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS05120
gene id: 93378:I6G97_RS05120
uniprot id: A0A376DLK1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

93378:I6G97 RS12040
gene id: 93378:I6G97_RS12040
uniprot id: A0A376DEZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS01900
gene id: 93378:I6G97_RS01900
uniprot id: A0A376D7C8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

93378:I6G97 RS17355
gene id: 93378:I6G97_RS17355
uniprot id: A0A376D8J7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

93378:I6G97 RS02580
gene id: 93378:I6G97_RS02580
uniprot id: A0A376D6A2
names: Subcellular Location Annotation
messages: Cell inner membrane

93378:I6G97 RS01980
gene id: 93378:I6G97_RS01980
uniprot id: A0A376D8I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

93378:I6G97 RS09055
gene id: 93378:I6G97_RS09055
uniprot id: A0A376DI98
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS04250
gene id: 93378:I6G97_RS04250
uniprot id: A0A376DNC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

93378:I6G97 RS06720
gene id: 93378:I6G97_RS06720
uniprot id: A0A376DKG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

93378:I6G97 RS06255
gene id: 93378:I6G97_RS06255
uniprot id: A0A376DL05
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

93378:I6G97 RS03835
gene id: 93378:I6G97_RS03835
uniprot id: A0A376DN29
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

93378:I6G97 RS17530
gene id: 93378:I6G97_RS17530
uniprot id: A0A376D8V8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Homodimer.

93378:I6G97 RS05935
gene id: 93378:I6G97_RS05935
uniprot id: A0A376DLA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

93378:I6G97 RS14320
gene id: 93378:I6G97_RS14320
uniprot id: A0A376DCA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

93378:I6G97 RS09280
gene id: 93378:I6G97_RS09280
uniprot id: A0A376DHZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

93378:I6G97 RS13915
gene id: 93378:I6G97_RS13915
uniprot id: A0A376DDE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Flagellar protein that affects chemotactic events.
messages: Membrane

93378:I6G97 RS01080
gene id: 93378:I6G97_RS01080
uniprot id: A0A376D845
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nucleoside:H(+) symporter (NHS) (TC 2.A.1.10) family.
messages: Broad-specificity transporter of purine and pyrimidine nucleosides. Transport is driven by a proton motive force.
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS07990
gene id: 93378:I6G97_RS07990
uniprot id: A0A376DKG6
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS03155
gene id: 93378:I6G97_RS03155
uniprot id: A0A376D583
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

93378:I6G97 RS14220
gene id: 93378:I6G97_RS14220
uniprot id: A0A376DDH8
names: Subcellular Location Annotation
messages: Cytoplasm

93378:I6G97 RS02145
gene id: 93378:I6G97_RS02145
uniprot id: A0A376D5V2
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

93378:I6G97 RS11320
gene id: 93378:I6G97_RS11320
uniprot id: A0A376DHR7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Multidrug efflux pump that functions probably as a Na(+)/drug antiporter.

93378:I6G97 RS06165
gene id: 93378:I6G97_RS06165
uniprot id: A0A376DML2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

93378:I6G97 RS01475
gene id: 93378:I6G97_RS01475
uniprot id: A0A376D844
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

93378:I6G97 RS02645
gene id: 93378:I6G97_RS02645
uniprot id: A0A376D5C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS17005
gene id: 93378:I6G97_RS17005
uniprot id: A0A376D9R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity. Interacts with IscU.

93378:I6G97 RS06875
gene id: 93378:I6G97_RS06875
uniprot id: A0A376DKA7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

93378:I6G97 RS00980
gene id: 93378:I6G97_RS00980
uniprot id: A0A376D7F5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

93378:I6G97 RS10500
gene id: 93378:I6G97_RS10500
uniprot id: A0A376DGR1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

93378:I6G97 RS06845
gene id: 93378:I6G97_RS06845
uniprot id: A0A376DKC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

93378:I6G97 RS06380
gene id: 93378:I6G97_RS06380
uniprot id: A0A376DKU2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

93378:I6G97 RS17235
gene id: 93378:I6G97_RS17235
uniprot id: A0A376D8C3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

93378:I6G97 RS02425
gene id: 93378:I6G97_RS02425
uniprot id: A0A376D5U9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

93378:I6G97 RS01455
gene id: 93378:I6G97_RS01455
uniprot id: A0A376D782
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

93378:I6G97 RS04045
gene id: 93378:I6G97_RS04045
uniprot id: A0A376DMZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 56 family.
messages: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis.
messages: Cell inner membrane

93378:I6G97 RS08790
gene id: 93378:I6G97_RS08790
uniprot id: A0A376DID3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

93378:I6G97 RS06425
gene id: 93378:I6G97_RS06425
uniprot id: A0A376DM77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RcsF family.
messages: Cell outer membrane
messages: Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects.

93378:I6G97 RS13725
gene id: 93378:I6G97_RS13725
uniprot id: A0A376DCT2
names: Similarity
names: Subunit
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

93378:I6G97 RS03345
gene id: 93378:I6G97_RS03345
uniprot id: A0A376DNM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

93378:I6G97 RS05310
gene id: 93378:I6G97_RS05310
uniprot id: A0A376DLT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

93378:I6G97 RS13455
gene id: 93378:I6G97_RS13455
uniprot id: A0A376DD45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Cell inner membrane
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

93378:I6G97 RS17495
gene id: 93378:I6G97_RS17495
uniprot id: A0A376D9K9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

93378:I6G97 RS04105
gene id: 93378:I6G97_RS04105
uniprot id: A0A376DPU0
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

93378:I6G97 RS14815
gene id: 93378:I6G97_RS14815
uniprot id: A0A376DBC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

93378:I6G97 RS13425
gene id: 93378:I6G97_RS13425
uniprot id: A0A376DD52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: Membrane

93378:I6G97 RS07735
gene id: 93378:I6G97_RS07735
uniprot id: A0A376DJM1
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS07925
gene id: 93378:I6G97_RS07925
uniprot id: A0A376DJE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

93378:I6G97 RS11785
gene id: 93378:I6G97_RS11785
uniprot id: A0A376DFG6
names: Similarity
messages: Belongs to the UPF0181 family.

93378:I6G97 RS02350
gene id: 93378:I6G97_RS02350
uniprot id: A0A376D668
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

93378:I6G97 RS01285
gene id: 93378:I6G97_RS01285
uniprot id: A0A376D827
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

93378:I6G97 RS07290
gene id: 93378:I6G97_RS07290
uniprot id: A0A376DJW7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

93378:I6G97 RS13275
gene id: 93378:I6G97_RS13275
uniprot id: A0A376DDH2
names: Similarity
messages: Belongs to the fabD family.

93378:I6G97 RS16240
gene id: 93378:I6G97_RS16240
uniprot id: A0A376DBV6
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

93378:I6G97 RS11915
gene id: 93378:I6G97_RS11915
uniprot id: A0A376DF84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Vitamin B12 importer (TC 3.A.1.13.1) family.
messages: Cell membrane
messages: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).

93378:I6G97 RS13245
gene id: 93378:I6G97_RS13245
uniprot id: A0A376DEI2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

93378:I6G97 RS02625
gene id: 93378:I6G97_RS02625
uniprot id: A0A376D5D7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

93378:I6G97 RS16220
gene id: 93378:I6G97_RS16220
uniprot id: A0A376D9Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

93378:I6G97 RS03165
gene id: 93378:I6G97_RS03165
uniprot id: A0A376D4X3
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

93378:I6G97 RS06700
gene id: 93378:I6G97_RS06700
uniprot id: A0A376DKH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

93378:I6G97 RS15925
gene id: 93378:I6G97_RS15925
uniprot id: A0A376DA86
names: Similarity
messages: Belongs to the YjdM family.

93378:I6G97 RS05945
gene id: 93378:I6G97_RS05945
uniprot id: A0A376DLG4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

93378:I6G97 RS16235
gene id: 93378:I6G97_RS16235
uniprot id: A0A376D9T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

93378:I6G97 RS08680
gene id: 93378:I6G97_RS08680
uniprot id: A0A376DJN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

93378:I6G97 RS06220
gene id: 93378:I6G97_RS06220
uniprot id: A0A376DLS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

93378:I6G97 RS13435
gene id: 93378:I6G97_RS13435
uniprot id: A0A376DDW6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

93378:I6G97 RS11145
gene id: 93378:I6G97_RS11145
uniprot id: A0A376DG43
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS02225
gene id: 93378:I6G97_RS02225
uniprot id: A0A376D5S6
names: Similarity
messages: Belongs to the HSP15 family.

93378:I6G97 RS10920
gene id: 93378:I6G97_RS10920
uniprot id: A0A376DI53
names: Similarity
messages: Belongs to the asparaginase 1 family.

93378:I6G97 RS01050
gene id: 93378:I6G97_RS01050
uniprot id: A0A376D742
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

93378:I6G97 RS17285
gene id: 93378:I6G97_RS17285
uniprot id: A0A376D8H1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

93378:I6G97 RS05585
gene id: 93378:I6G97_RS05585
uniprot id: A0A376DM80
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

93378:I6G97 RS02820
gene id: 93378:I6G97_RS02820
uniprot id: A0A376D6I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

93378:I6G97 RS08195
gene id: 93378:I6G97_RS08195
uniprot id: A0A376DJ18
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS11410
gene id: 93378:I6G97_RS11410
uniprot id: A0A376DGC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

93378:I6G97 RS08100
gene id: 93378:I6G97_RS08100
uniprot id: A0A376DIN5
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

93378:I6G97 RS14140
gene id: 93378:I6G97_RS14140
uniprot id: A0A376DCB9
names: Function
names: Similarity
messages: Belongs to the TorD/DmsD family. DmsD subfamily.
messages: Required for biogenesis/assembly of DMSO reductase, but not for the interaction of the DmsA signal peptide with the Tat system. May be part of a chaperone cascade complex that facilitates a folding-maturation pathway for the substrate protein.

93378:I6G97 RS11015
gene id: 93378:I6G97_RS11015
uniprot id: A0A376DHB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

93378:I6G97 RS14820
gene id: 93378:I6G97_RS14820
uniprot id: A0A376DBP4
names: Similarity
messages: Belongs to the flavodoxin family.

93378:I6G97 RS11075
gene id: 93378:I6G97_RS11075
uniprot id: A0A376DG15
names: Similarity
messages: Belongs to the Dps family.

93378:I6G97 RS13670
gene id: 93378:I6G97_RS13670
uniprot id: A0A376DD59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

93378:I6G97 RS13070
gene id: 93378:I6G97_RS13070
uniprot id: A0A376DDG7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93378:I6G97 RS03565
gene id: 93378:I6G97_RS03565
uniprot id: A0A376DP09
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

93378:I6G97 RS05530
gene id: 93378:I6G97_RS05530
uniprot id: A0A376DN07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

93378:I6G97 RS14490
gene id: 93378:I6G97_RS14490
uniprot id: A0A376DCS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

93378:I6G97 RS05375
gene id: 93378:I6G97_RS05375
uniprot id: A0A376DLD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

93378:I6G97 RS06550
gene id: 93378:I6G97_RS06550
uniprot id: A0A376DMM7
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS00810
gene id: 93378:I6G97_RS00810
uniprot id: A0A376D8L0
names: Similarity
messages: Belongs to the RecJ family.

93378:I6G97 RS11605
gene id: 93378:I6G97_RS11605
uniprot id: A0A376DF36
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

93378:I6G97 RS17455
gene id: 93378:I6G97_RS17455
uniprot id: A0A376D8C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

93378:I6G97 RS07785
gene id: 93378:I6G97_RS07785
uniprot id: A0A376DKH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LsrG family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the conversion of (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5-phosphonooxypentane-2,4-dione (P-HPD).

93378:I6G97 RS12475
gene id: 93378:I6G97_RS12475
uniprot id: A0A376DEM7
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

93378:I6G97 RS06800
gene id: 93378:I6G97_RS06800
uniprot id: A0A376DKK7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS16525
gene id: 93378:I6G97_RS16525
uniprot id: A0A376DAB9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

93378:I6G97 RS07755
gene id: 93378:I6G97_RS07755
uniprot id: A0A376DJI9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

93378:I6G97 RS05565
gene id: 93378:I6G97_RS05565
uniprot id: A0A376DNJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS13065
gene id: 93378:I6G97_RS13065
uniprot id: A0A376DFP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

93378:I6G97 RS09385
gene id: 93378:I6G97_RS09385
uniprot id: A0A376DID1
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

93378:I6G97 RS07235
gene id: 93378:I6G97_RS07235
uniprot id: A0A376DJZ0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93378:I6G97 RS02880
gene id: 93378:I6G97_RS02880
uniprot id: A0A376D7G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

93378:I6G97 RS10455
gene id: 93378:I6G97_RS10455
uniprot id: A0A376DGI6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS09350
gene id: 93378:I6G97_RS09350
uniprot id: A0A376DHV6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

93378:I6G97 RS15705
gene id: 93378:I6G97_RS15705
uniprot id: A0A376DAE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

93378:I6G97 RS07400
gene id: 93378:I6G97_RS07400
uniprot id: A0A376DJH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

93378:I6G97 RS01725
gene id: 93378:I6G97_RS01725
uniprot id: A0A376D6B9
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

93378:I6G97 RS16540
gene id: 93378:I6G97_RS16540
uniprot id: A0A376D977
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

93378:I6G97 RS09370
gene id: 93378:I6G97_RS09370
uniprot id: A0A376DJ12
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

93378:I6G97 RS11210
gene id: 93378:I6G97_RS11210
uniprot id: A0A376DFS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

93378:I6G97 RS05110
gene id: 93378:I6G97_RS05110
uniprot id: A0A376DNB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

93378:I6G97 RS01940
gene id: 93378:I6G97_RS01940
uniprot id: A0A376D6Q2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

93378:I6G97 RS16995
gene id: 93378:I6G97_RS16995
uniprot id: A0A376D8M2
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

93378:I6G97 RS11670
gene id: 93378:I6G97_RS11670
uniprot id: A0A376DFB9
names: Similarity
messages: Belongs to the PspA/IM30 family.

93378:I6G97 RS16950
gene id: 93378:I6G97_RS16950
uniprot id: A0A376D957
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

93378:I6G97 RS05080
gene id: 93378:I6G97_RS05080
uniprot id: A0A376DNC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

93378:I6G97 RS12175
gene id: 93378:I6G97_RS12175
uniprot id: A0A376DEV8
names: Similarity
messages: Belongs to the UPF0381 family.

93378:I6G97 RS06790
gene id: 93378:I6G97_RS06790
uniprot id: A0A376DMD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

93378:I6G97 RS08880
gene id: 93378:I6G97_RS08880
uniprot id: A0A376DI21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

93378:I6G97 RS08495
gene id: 93378:I6G97_RS08495
uniprot id: A0A376DII2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93378:I6G97 RS06235
gene id: 93378:I6G97_RS06235
uniprot id: A0A376DKQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZapG family.
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS04395
gene id: 93378:I6G97_RS04395
uniprot id: A0A376DMK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NusG family.
messages: Monomer. Interacts with the transcription termination factor Rho and with RNA polymerase.
messages: Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination.

93378:I6G97 RS15820
gene id: 93378:I6G97_RS15820
uniprot id: A0A376DA81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

93378:I6G97 RS03975
gene id: 93378:I6G97_RS03975
uniprot id: A0A376DPX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

93378:I6G97 RS13270
gene id: 93378:I6G97_RS13270
uniprot id: A0A376DE88
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93378:I6G97 RS01345
gene id: 93378:I6G97_RS01345
uniprot id: A0A376D993
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

93378:I6G97 RS12320
gene id: 93378:I6G97_RS12320
uniprot id: A0A376DET2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

93378:I6G97 RS11690
gene id: 93378:I6G97_RS11690
uniprot id: A0A376DG16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0283 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

93378:I6G97 RS15300
gene id: 93378:I6G97_RS15300
uniprot id: A0A376DBX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

93378:I6G97 RS16070
gene id: 93378:I6G97_RS16070
uniprot id: A0A376DAR6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

93378:I6G97 RS12440
gene id: 93378:I6G97_RS12440
uniprot id: A0A376DEK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS10575
gene id: 93378:I6G97_RS10575
uniprot id: A0A376DII7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the PHP family.
messages: Binds 3 Zn(2+) ions per subunit.
messages: Homotrimer.

93378:I6G97 RS08500
gene id: 93378:I6G97_RS08500
uniprot id: A0A376DJP4
names: Similarity
messages: Belongs to the PrpD family.

93378:I6G97 RS09620
gene id: 93378:I6G97_RS09620
uniprot id: A0A376DHG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArnF family.
messages: Cell inner membrane
messages: Heterodimer of ArnE and ArnF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.

93378:I6G97 RS15775
gene id: 93378:I6G97_RS15775
uniprot id: A0A376DB35
names: Similarity
messages: Belongs to the aldose epimerase family.

93378:I6G97 RS02865
gene id: 93378:I6G97_RS02865
uniprot id: A0A376D5B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

93378:I6G97 RS16850
gene id: 93378:I6G97_RS16850
uniprot id: A0A376D9J1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

93378:I6G97 RS11110
gene id: 93378:I6G97_RS11110
uniprot id: A0A376DFW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0259 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

93378:I6G97 RS01880
gene id: 93378:I6G97_RS01880
uniprot id: A0A376D771
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

93378:I6G97 RS04305
gene id: 93378:I6G97_RS04305
uniprot id: A0A376DMM4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

93378:I6G97 RS03100
gene id: 93378:I6G97_RS03100
uniprot id: A0A376D531
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

93378:I6G97 RS16330
gene id: 93378:I6G97_RS16330
uniprot id: A0A376D9Q4
names: Function
names: Similarity
messages: Belongs to the ETF-QO/FixC family.
messages: Part of an electron transfer system.

93378:I6G97 RS01745
gene id: 93378:I6G97_RS01745
uniprot id: A0A376D6B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

93378:I6G97 RS16005
gene id: 93378:I6G97_RS16005
uniprot id: A0A376DAT4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

93378:I6G97 RS14535
gene id: 93378:I6G97_RS14535
uniprot id: A0A376DC24
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

93378:I6G97 RS04225
gene id: 93378:I6G97_RS04225
uniprot id: A0A376DNR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine to uracil and ribose-1-phosphate.
messages: Cytoplasm

93378:I6G97 RS01535
gene id: 93378:I6G97_RS01535
uniprot id: A0A376D820
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

93378:I6G97 RS05215
gene id: 93378:I6G97_RS05215
uniprot id: A0A376DM09
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

93378:I6G97 RS09305
gene id: 93378:I6G97_RS09305
uniprot id: A0A376DHE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

93378:I6G97 RS13385
gene id: 93378:I6G97_RS13385
uniprot id: A0A376DEG8
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

93378:I6G97 RS05695
gene id: 93378:I6G97_RS05695
uniprot id: A0A376DLL1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS16545
gene id: 93378:I6G97_RS16545
uniprot id: A0A376DAB0
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS07365
gene id: 93378:I6G97_RS07365
uniprot id: A0A376DJY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

93378:I6G97 RS08185
gene id: 93378:I6G97_RS08185
uniprot id: A0A376DIU8
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

93378:I6G97 RS15230
gene id: 93378:I6G97_RS15230
uniprot id: A0A376DB09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

93378:I6G97 RS12255
gene id: 93378:I6G97_RS12255
uniprot id: A0A376DEP2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93378:I6G97 RS07775
gene id: 93378:I6G97_RS07775
uniprot id: A0A376DJH6
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.

93378:I6G97 RS06160
gene id: 93378:I6G97_RS06160
uniprot id: A0A376DMA5
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

93378:I6G97 RS17565
gene id: 93378:I6G97_RS17565
uniprot id: A0A376D936
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

93378:I6G97 RS10665
gene id: 93378:I6G97_RS10665
uniprot id: A0A376DIF7
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

93378:I6G97 RS15970
gene id: 93378:I6G97_RS15970
uniprot id: A0A376DA70
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93378:I6G97 RS01440
gene id: 93378:I6G97_RS01440
uniprot id: A0A376D6Z6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

93378:I6G97 RS08310
gene id: 93378:I6G97_RS08310
uniprot id: A0A376DKR5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

93378:I6G97 RS03910
gene id: 93378:I6G97_RS03910
uniprot id: A0A376DPZ3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

93378:I6G97 RS02470
gene id: 93378:I6G97_RS02470
uniprot id: A0A376D5R2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

93378:I6G97 RS05065
gene id: 93378:I6G97_RS05065
uniprot id: A0A376DM46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

93378:I6G97 RS10040
gene id: 93378:I6G97_RS10040
uniprot id: A0A376DH06
names: Similarity
messages: Belongs to the phage antitermination Q type 1 family.

93378:I6G97 RS12390
gene id: 93378:I6G97_RS12390
uniprot id: A0A376DGK2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

93378:I6G97 RS05305
gene id: 93378:I6G97_RS05305
uniprot id: A0A376DN71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PriB family.
messages: Binds single-stranded DNA at the primosome assembly site (PAS).
messages: Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome.

93378:I6G97 RS11175
gene id: 93378:I6G97_RS11175
uniprot id: A0A376DFY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

93378:I6G97 RS03810
gene id: 93378:I6G97_RS03810
uniprot id: A0A376DN48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

93378:I6G97 RS12140
gene id: 93378:I6G97_RS12140
uniprot id: A0A376DGW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

93378:I6G97 RS15150
gene id: 93378:I6G97_RS15150
uniprot id: A0A376DBT3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

93378:I6G97 RS10680
gene id: 93378:I6G97_RS10680
uniprot id: A0A376DHH8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

93378:I6G97 RS11065
gene id: 93378:I6G97_RS11065
uniprot id: A0A376DH92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

93378:I6G97 RS05360
gene id: 93378:I6G97_RS05360
uniprot id: A0A376DLQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

93378:I6G97 RS09080
gene id: 93378:I6G97_RS09080
uniprot id: A0A376DHN1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

93378:I6G97 RS08570
gene id: 93378:I6G97_RS08570
uniprot id: A0A376DJ66
names: Subcellular Location Annotation
messages: Cell inner membrane

93378:I6G97 RS04080
gene id: 93378:I6G97_RS04080
uniprot id: A0A376DMZ4
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

93378:I6G97 RS16480
gene id: 93378:I6G97_RS16480
uniprot id: A0A376D9L4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

93378:I6G97 RS13830
gene id: 93378:I6G97_RS13830
uniprot id: A0A376DCH3
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

93378:I6G97 RS16215
gene id: 93378:I6G97_RS16215
uniprot id: A0A376DA84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

93378:I6G97 RS06295
gene id: 93378:I6G97_RS06295
uniprot id: A0A376DKY6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93378:I6G97 RS03065
gene id: 93378:I6G97_RS03065
uniprot id: A0A376D530
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.

93378:I6G97 RS16895
gene id: 93378:I6G97_RS16895
uniprot id: A0A376DA87
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

93378:I6G97 RS00870
gene id: 93378:I6G97_RS00870
uniprot id: A0A376D7K3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

93378:I6G97 RS13760
gene id: 93378:I6G97_RS13760
uniprot id: A0A376DCW6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

93378:I6G97 RS07295
gene id: 93378:I6G97_RS07295
uniprot id: A0A376DL10
names: Activity Regulation
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

93378:I6G97 RS08270
gene id: 93378:I6G97_RS08270
uniprot id: A0A376DJ00
names: Similarity
messages: Belongs to the P(II) protein family.

93378:I6G97 RS06485
gene id: 93378:I6G97_RS06485
uniprot id: A0A376DLF2
names: Similarity
messages: Belongs to the thioredoxin family.

93378:I6G97 RS11220
gene id: 93378:I6G97_RS11220
uniprot id: A0A376DG17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

93378:I6G97 RS08975
gene id: 93378:I6G97_RS08975
uniprot id: A0A376DJG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

93378:I6G97 RS05160
gene id: 93378:I6G97_RS05160
uniprot id: A0A376DM16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

93378:I6G97 RS04190
gene id: 93378:I6G97_RS04190
uniprot id: A0A376DMR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

93378:I6G97 RS16180
gene id: 93378:I6G97_RS16180
uniprot id: A0A376DAQ3
names: Function
names: Similarity
messages: Belongs to the IUNH family. RihA subfamily.
messages: Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively.

93378:I6G97 RS11900
gene id: 93378:I6G97_RS11900
uniprot id: A0A376DFC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

93378:I6G97 RS16690
gene id: 93378:I6G97_RS16690
uniprot id: A0A376D934
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. SrmB subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity.
messages: Interacts with the 50S ribosomal subunit.

93378:I6G97 RS12035
gene id: 93378:I6G97_RS12035
uniprot id: A0A376DFP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

93378:I6G97 RS04870
gene id: 93378:I6G97_RS04870
uniprot id: A0A376DM51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

93378:I6G97 RS13895
gene id: 93378:I6G97_RS13895
uniprot id: A0A376DDN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

93378:I6G97 RS11845
gene id: 93378:I6G97_RS11845
uniprot id: A0A376DFW7
names: Similarity
messages: Belongs to the Dps family.

93378:I6G97 RS05125
gene id: 93378:I6G97_RS05125
uniprot id: A0A376DLX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

93378:I6G97 RS11580
gene id: 93378:I6G97_RS11580
uniprot id: A0A376DFI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

93378:I6G97 RS08595
gene id: 93378:I6G97_RS08595
uniprot id: A0A376DJ57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA gyrase inhibitor family.
messages: Cytoplasm
messages: Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell.
messages: Interacts with DNA gyrase.

93378:I6G97 RS03025
gene id: 93378:I6G97_RS03025
uniprot id: A0A376D5S1
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activity of this regulatory enzyme is affected by several metabolites. Allosterically and non-competitively inhibited by fructose 1,6-bisphosphate (FBP) and unphosphorylated phosphocarrier protein EIIA-Glc (III-Glc), an integral component of the bacterial phosphotransferase (PTS) system.
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium). Heterodimer with EIIA-Glc. Binds 1 zinc ion per glycerol kinase EIIA-Glc dimer. The zinc ion is important for dimerization.
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

93378:I6G97 RS03405
gene id: 93378:I6G97_RS03405
uniprot id: A0A376DPW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

93378:I6G97 RS06325
gene id: 93378:I6G97_RS06325
uniprot id: A0A376DKY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

93378:I6G97 RS02340
gene id: 93378:I6G97_RS02340
uniprot id: A0A376D750
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

93378:I6G97 RS17540
gene id: 93378:I6G97_RS17540
uniprot id: A0A376D949
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

93378:I6G97 RS04035
gene id: 93378:I6G97_RS04035
uniprot id: A0A376DNW8
names: Function
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.
messages: Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D-galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D-Glc4O) and L-glutamate.

93378:I6G97 RS17365
gene id: 93378:I6G97_RS17365
uniprot id: A0A376D8E2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

93378:I6G97 RS06365
gene id: 93378:I6G97_RS06365
uniprot id: A0A376DMA9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

93378:I6G97 RS15895
gene id: 93378:I6G97_RS15895
uniprot id: A0A376D9T5
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

93378:I6G97 RS15110
gene id: 93378:I6G97_RS15110
uniprot id: A0A376DC96
names: Subunit
messages: Homooctamer.

93378:I6G97 RS04930
gene id: 93378:I6G97_RS04930
uniprot id: A0A376DM82
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

93378:I6G97 RS00375
gene id: 93378:I6G97_RS00375
uniprot id: A0A376D8A1
names: Similarity
messages: Belongs to the HypD family.

93378:I6G97 RS00990
gene id: 93378:I6G97_RS00990
uniprot id: A0A376D8P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

93378:I6G97 RS00880
gene id: 93378:I6G97_RS00880
uniprot id: A0A376D7A3
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

93378:I6G97 RS08115
gene id: 93378:I6G97_RS08115
uniprot id: A0A376DKC4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

93378:I6G97 RS06945
gene id: 93378:I6G97_RS06945
uniprot id: A0A376DM85
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

93378:I6G97 RS01665
gene id: 93378:I6G97_RS01665
uniprot id: A0A376D7X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

93378:I6G97 RS10625
gene id: 93378:I6G97_RS10625
uniprot id: A0A376DH56
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

93378:I6G97 RS00240
gene id: 93378:I6G97_RS00240
uniprot id: A0A376IY39
names: Function
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane protein involved in F pilin formation.

93378:I6G97 RS06520
gene id: 93378:I6G97_RS06520
uniprot id: A0A376DMN7
names: Similarity
messages: Belongs to the UPF0246 family.

93378:I6G97 RS11245
gene id: 93378:I6G97_RS11245
uniprot id: A0A376DG07
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93378:I6G97 RS16610
gene id: 93378:I6G97_RS16610
uniprot id: A0A376D9F0
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

93378:I6G97 RS13805
gene id: 93378:I6G97_RS13805
uniprot id: A0A376DD21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

93378:I6G97 RS00935
gene id: 93378:I6G97_RS00935
uniprot id: A0A376D8R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
messages: Cell membrane
messages: Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine.
messages: Membrane

93378:I6G97 RS06065
gene id: 93378:I6G97_RS06065
uniprot id: A0A376DLE3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS00185
gene id: 93378:I6G97_RS00185
uniprot id: A0A376IY29
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS04445
gene id: 93378:I6G97_RS04445
uniprot id: A0A376DMH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

93378:I6G97 RS15515
gene id: 93378:I6G97_RS15515
uniprot id: A0A376DAI9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

93378:I6G97 RS13985
gene id: 93378:I6G97_RS13985
uniprot id: A0A376DCM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MukF family.
messages: Interacts, and probably forms a ternary complex, with MukE and MukB via its C-terminal region. The complex formation is stimulated by calcium or magnesium. It is required for an interaction between MukE and MukB.
messages: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
messages: nucleoid

93378:I6G97 RS00960
gene id: 93378:I6G97_RS00960
uniprot id: A0A376D8Q8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

93378:I6G97 RS01670
gene id: 93378:I6G97_RS01670
uniprot id: A0A376D8W0
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

93378:I6G97 RS06435
gene id: 93378:I6G97_RS06435
uniprot id: A0A376DKZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93378:I6G97 RS03955
gene id: 93378:I6G97_RS03955
uniprot id: A0A376DMY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

93378:I6G97 RS03095
gene id: 93378:I6G97_RS03095
uniprot id: A0A376D4Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

93378:I6G97 RS04510
gene id: 93378:I6G97_RS04510
uniprot id: A0A376DMM2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

93378:I6G97 RS04465
gene id: 93378:I6G97_RS04465
uniprot id: A0A376DN67
names: Similarity
messages: Belongs to the GARS family.

93378:I6G97 RS00955
gene id: 93378:I6G97_RS00955
uniprot id: A0A376D7G4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
messages: Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS02550
gene id: 93378:I6G97_RS02550
uniprot id: A0A376D5Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. Pit subfamily.
messages: Membrane

93378:I6G97 RS11830
gene id: 93378:I6G97_RS11830
uniprot id: A0A376DF63
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Membrane

93378:I6G97 RS08045
gene id: 93378:I6G97_RS08045
uniprot id: A0A376DKE6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

93378:I6G97 RS00825
gene id: 93378:I6G97_RS00825
uniprot id: A0A376D7C1
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

93378:I6G97 RS09330
gene id: 93378:I6G97_RS09330
uniprot id: A0A376DHX6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

93378:I6G97 RS04885
gene id: 93378:I6G97_RS04885
uniprot id: A0A376DNI1
names: Similarity
messages: Belongs to the YggT family.

93378:I6G97 RS04670
gene id: 93378:I6G97_RS04670
uniprot id: A0A376DM98
names: Subcellular Location Annotation
messages: Cytoplasm

93378:I6G97 RS14740
gene id: 93378:I6G97_RS14740
uniprot id: A0A376DCF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

93378:I6G97 RS16880
gene id: 93378:I6G97_RS16880
uniprot id: A0A376D8S4
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

93378:I6G97 RS12485
gene id: 93378:I6G97_RS12485
uniprot id: A0A376DFF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS08370
gene id: 93378:I6G97_RS08370
uniprot id: A0A376DIU7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

93378:I6G97 RS03965
gene id: 93378:I6G97_RS03965
uniprot id: A0A376DNZ5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93378:I6G97 RS13300
gene id: 93378:I6G97_RS13300
uniprot id: A0A376DEF4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MdcC family.
messages: Covalently binds the prosthetic group of malonate decarboxylase.
messages: Cytoplasm
messages: Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism.

93378:I6G97 RS00450
gene id: 93378:I6G97_RS00450
uniprot id: A0A376D901
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

93378:I6G97 RS10430
gene id: 93378:I6G97_RS10430
uniprot id: A0A376DHX7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93378:I6G97 RS03990
gene id: 93378:I6G97_RS03990
uniprot id: A0A376DMX5
names: Similarity
messages: Belongs to the thioredoxin family.

93378:I6G97 RS15375
gene id: 93378:I6G97_RS15375
uniprot id: A0A376DBU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

93378:I6G97 RS11490
gene id: 93378:I6G97_RS11490
uniprot id: A0A376DFI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

93378:I6G97 RS01765
gene id: 93378:I6G97_RS01765
uniprot id: A0A376D767
names: Subunit
messages: Monomer.

93378:I6G97 RS15585
gene id: 93378:I6G97_RS15585
uniprot id: A0A376DAS3
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

93378:I6G97 RS13855
gene id: 93378:I6G97_RS13855
uniprot id: A0A376DCS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

93378:I6G97 RS17380
gene id: 93378:I6G97_RS17380
uniprot id: A0A376D877
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

93378:I6G97 RS02320
gene id: 93378:I6G97_RS02320
uniprot id: A0A376D685
names: Similarity
messages: Belongs to the UPF0270 family.

93378:I6G97 RS10770
gene id: 93378:I6G97_RS10770
uniprot id: A0A376DHE6
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

93378:I6G97 RS17385
gene id: 93378:I6G97_RS17385
uniprot id: A0A376D8P9
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

93378:I6G97 RS06020
gene id: 93378:I6G97_RS06020
uniprot id: A0A376DLE9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

93378:I6G97 RS02640
gene id: 93378:I6G97_RS02640
uniprot id: A0A376D675
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

93378:I6G97 RS13785
gene id: 93378:I6G97_RS13785
uniprot id: A0A376DDI9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

93378:I6G97 RS17030
gene id: 93378:I6G97_RS17030
uniprot id: A0A376D9P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

93378:I6G97 RS10815
gene id: 93378:I6G97_RS10815
uniprot id: A0A376DGC3
names: Similarity
messages: Belongs to the UPF0260 family.

93378:I6G97 RS10955
gene id: 93378:I6G97_RS10955
uniprot id: A0A376DG54
names: Similarity
messages: Belongs to the Nudix hydrolase family.

93378:I6G97 RS08050
gene id: 93378:I6G97_RS08050
uniprot id: A0A376DJ89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

93378:I6G97 RS09065
gene id: 93378:I6G97_RS09065
uniprot id: A0A376DJ72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

93378:I6G97 RS05365
gene id: 93378:I6G97_RS05365
uniprot id: A0A376DN53
names: Subcellular Location Annotation
messages: Membrane

93378:I6G97 RS08355
gene id: 93378:I6G97_RS08355
uniprot id: A0A376DJF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

93378:I6G97 RS03005
gene id: 93378:I6G97_RS03005
uniprot id: A0A376D559
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

93378:I6G97 RS05000
gene id: 93378:I6G97_RS05000
uniprot id: A0A376DLN7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Exported by the Tat system.
messages: Periplasm
messages: Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions.

93378:I6G97 RS13675
gene id: 93378:I6G97_RS13675
uniprot id: A0A376DCY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

93378:I6G97 RS03925
gene id: 93378:I6G97_RS03925
uniprot id: A0A376DNM0
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

93378:I6G97 RS14645
gene id: 93378:I6G97_RS14645
uniprot id: A0A376DBX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

93378:I6G97 RS13020
gene id: 93378:I6G97_RS13020
uniprot id: A0A376DER7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (NikD and NikE), two transmembrane proteins (NikB and NikC) and a solute-binding protein (NikA).