929713:NIASO RS16455
gene id: 929713:NIASO_RS16455
uniprot id: W0F4X3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

929713:NIASO RS12635
gene id: 929713:NIASO_RS12635
uniprot id: W0F290
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS02605
gene id: 929713:NIASO_RS02605
uniprot id: W0EYZ0
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

929713:NIASO RS07425
gene id: 929713:NIASO_RS07425
uniprot id: W0EWF5
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

929713:NIASO RS00940
gene id: 929713:NIASO_RS00940
uniprot id: W0F1X4
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS12415
gene id: 929713:NIASO_RS12415
uniprot id: W0F8G4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

929713:NIASO RS13865
gene id: 929713:NIASO_RS13865
uniprot id: W0F450
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS13215
gene id: 929713:NIASO_RS13215
uniprot id: W0F3T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

929713:NIASO RS14690
gene id: 929713:NIASO_RS14690
uniprot id: W0EZL8
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

929713:NIASO RS07185
gene id: 929713:NIASO_RS07185
uniprot id: W0F157
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

929713:NIASO RS04295
gene id: 929713:NIASO_RS04295
uniprot id: W0EZR6
names: Similarity
messages: Belongs to the thioredoxin family.

929713:NIASO RS04250
gene id: 929713:NIASO_RS04250
uniprot id: W0EYP4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

929713:NIASO RS10355
gene id: 929713:NIASO_RS10355
uniprot id: W0F167
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

929713:NIASO RS06905
gene id: 929713:NIASO_RS06905
uniprot id: W0EW74
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS08770
gene id: 929713:NIASO_RS08770
uniprot id: W0F0I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

929713:NIASO RS13920
gene id: 929713:NIASO_RS13920
uniprot id: W0EZ72
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS08230
gene id: 929713:NIASO_RS08230
uniprot id: W0EWR8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

929713:NIASO RS05155
gene id: 929713:NIASO_RS05155
uniprot id: W0EVI5
names: PTM
messages: Binds 1 heme c group covalently per subunit.

929713:NIASO RS15775
gene id: 929713:NIASO_RS15775
uniprot id: W0F503
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

929713:NIASO RS06875
gene id: 929713:NIASO_RS06875
uniprot id: W0EZM6
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS06650
gene id: 929713:NIASO_RS06650
uniprot id: W0EW28
names: Similarity
messages: Belongs to the SufE family.

929713:NIASO RS04275
gene id: 929713:NIASO_RS04275
uniprot id: W0EV83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

929713:NIASO RS06775
gene id: 929713:NIASO_RS06775
uniprot id: W0EZK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

929713:NIASO RS03930
gene id: 929713:NIASO_RS03930
uniprot id: W0EZT6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

929713:NIASO RS11385
gene id: 929713:NIASO_RS11385
uniprot id: W0EYA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

929713:NIASO RS07480
gene id: 929713:NIASO_RS07480
uniprot id: W0EWG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS11055
gene id: 929713:NIASO_RS11055
uniprot id: W0F2I1
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

929713:NIASO RS09380
gene id: 929713:NIASO_RS09380
uniprot id: W0F1S5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

929713:NIASO RS02040
gene id: 929713:NIASO_RS02040
uniprot id: W0EXP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

929713:NIASO RS03715
gene id: 929713:NIASO_RS03715
uniprot id: W0EUX8
names: Similarity
messages: Belongs to the acylphosphatase family.

929713:NIASO RS18170
gene id: 929713:NIASO_RS18170
uniprot id: W0F154
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS00260
gene id: 929713:NIASO_RS00260
uniprot id: W0ETF8
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

929713:NIASO RS09075
gene id: 929713:NIASO_RS09075
uniprot id: W0F221
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

929713:NIASO RS14200
gene id: 929713:NIASO_RS14200
uniprot id: W0F3S1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS13530
gene id: 929713:NIASO_RS13530
uniprot id: W0EZ56
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

929713:NIASO RS01120
gene id: 929713:NIASO_RS01120
uniprot id: W0ETW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

929713:NIASO RS17835
gene id: 929713:NIASO_RS17835
uniprot id: W0F4L1
names: Similarity
messages: Belongs to the fabD family.

929713:NIASO RS01495
gene id: 929713:NIASO_RS01495
uniprot id: W0EU02
names: Subcellular Location Annotation
messages: Cytoplasm

929713:NIASO RS07025
gene id: 929713:NIASO_RS07025
uniprot id: W0EZP3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS06615
gene id: 929713:NIASO_RS06615
uniprot id: W0EW08
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS07690
gene id: 929713:NIASO_RS07690
uniprot id: W0F022
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

929713:NIASO RS13845
gene id: 929713:NIASO_RS13845
uniprot id: W0F418
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS09485
gene id: 929713:NIASO_RS09485
uniprot id: W0EXD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

929713:NIASO RS11025
gene id: 929713:NIASO_RS11025
uniprot id: W0EY60
names: Similarity
messages: Belongs to the peptidase S51 family.

929713:NIASO RS04835
gene id: 929713:NIASO_RS04835
uniprot id: W0EZY9
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

929713:NIASO RS18370
gene id: 929713:NIASO_RS18370
uniprot id: W0F636
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS13405
gene id: 929713:NIASO_RS13405
uniprot id: W0F2J5
names: Similarity
messages: Belongs to the CarB family.

929713:NIASO RS00270
gene id: 929713:NIASO_RS00270
uniprot id: W0EXX6
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

929713:NIASO RS08200
gene id: 929713:NIASO_RS08200
uniprot id: W0F1C6
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

929713:NIASO RS03425
gene id: 929713:NIASO_RS03425
uniprot id: W0EUT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

929713:NIASO RS00635
gene id: 929713:NIASO_RS00635
uniprot id: W0EX12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

929713:NIASO RS17880
gene id: 929713:NIASO_RS17880
uniprot id: W0F5K3
names: Similarity
messages: Belongs to the RNA polymerase subunit omega family.

929713:NIASO RS05800
gene id: 929713:NIASO_RS05800
uniprot id: W0EZ90
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

929713:NIASO RS03985
gene id: 929713:NIASO_RS03985
uniprot id: W0EUZ6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

929713:NIASO RS10360
gene id: 929713:NIASO_RS10360
uniprot id: W0F265
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

929713:NIASO RS15515
gene id: 929713:NIASO_RS15515
uniprot id: W0F4H5
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

929713:NIASO RS15330
gene id: 929713:NIASO_RS15330
uniprot id: W0F4T0
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

929713:NIASO RS14480
gene id: 929713:NIASO_RS14480
uniprot id: W0F339
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

929713:NIASO RS17960
gene id: 929713:NIASO_RS17960
uniprot id: W0F4N2
names: Similarity
messages: Belongs to the SUI1 family.

929713:NIASO RS18450
gene id: 929713:NIASO_RS18450
uniprot id: W0F5S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Mitochondrion

929713:NIASO RS02580
gene id: 929713:NIASO_RS02580
uniprot id: W0EYY5
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

929713:NIASO RS12630
gene id: 929713:NIASO_RS12630
uniprot id: W0EYR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

929713:NIASO RS17455
gene id: 929713:NIASO_RS17455
uniprot id: W0F967
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

929713:NIASO RS10565
gene id: 929713:NIASO_RS10565
uniprot id: W0F288
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS15815
gene id: 929713:NIASO_RS15815
uniprot id: W0F4M5
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS11930
gene id: 929713:NIASO_RS11930
uniprot id: W0F1Z6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

929713:NIASO RS10245
gene id: 929713:NIASO_RS10245
uniprot id: W0EXM2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS01155
gene id: 929713:NIASO_RS01155
uniprot id: W0ETW6
names: Similarity
messages: Belongs to the sulfatase family.

929713:NIASO RS14010
gene id: 929713:NIASO_RS14010
uniprot id: W0F443
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

929713:NIASO RS13515
gene id: 929713:NIASO_RS13515
uniprot id: W0F3H5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

929713:NIASO RS03190
gene id: 929713:NIASO_RS03190
uniprot id: W0EUL9
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS10880
gene id: 929713:NIASO_RS10880
uniprot id: W0EY26
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

929713:NIASO RS04795
gene id: 929713:NIASO_RS04795
uniprot id: W0EVE3
names: Subcellular Location Annotation
messages: Cytoplasm

929713:NIASO RS07870
gene id: 929713:NIASO_RS07870
uniprot id: W0F183
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

929713:NIASO RS04405
gene id: 929713:NIASO_RS04405
uniprot id: W0EZT3
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

929713:NIASO RS14595
gene id: 929713:NIASO_RS14595
uniprot id: W0F359
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS09315
gene id: 929713:NIASO_RS09315
uniprot id: W0F0R7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

929713:NIASO RS15555
gene id: 929713:NIASO_RS15555
uniprot id: W0F4X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

929713:NIASO RS14475
gene id: 929713:NIASO_RS14475
uniprot id: W0EZN2
names: Similarity
messages: Belongs to the RutC family.

929713:NIASO RS14465
gene id: 929713:NIASO_RS14465
uniprot id: W0EZI5
names: Similarity
messages: Belongs to the sulfatase family.

929713:NIASO RS09320
gene id: 929713:NIASO_RS09320
uniprot id: W0F1R5
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

929713:NIASO RS17475
gene id: 929713:NIASO_RS17475
uniprot id: W0F5E6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

929713:NIASO RS14350
gene id: 929713:NIASO_RS14350
uniprot id: W0F4D1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

929713:NIASO RS06780
gene id: 929713:NIASO_RS06780
uniprot id: W0F0P7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

929713:NIASO RS12230
gene id: 929713:NIASO_RS12230
uniprot id: W0F3H6
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.

929713:NIASO RS10890
gene id: 929713:NIASO_RS10890
uniprot id: W0F2E0
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS18285
gene id: 929713:NIASO_RS18285
uniprot id: W0F170
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

929713:NIASO RS17535
gene id: 929713:NIASO_RS17535
uniprot id: W0F5T0
names: Subcellular Location Annotation
messages: Secreted

929713:NIASO RS14320
gene id: 929713:NIASO_RS14320
uniprot id: W0EZG6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

929713:NIASO RS18375
gene id: 929713:NIASO_RS18375
uniprot id: W0F1D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS01440
gene id: 929713:NIASO_RS01440
uniprot id: W0ETZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

929713:NIASO RS03260
gene id: 929713:NIASO_RS03260
uniprot id: W0F6Z2
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS11035
gene id: 929713:NIASO_RS11035
uniprot id: W0F2H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

929713:NIASO RS04895
gene id: 929713:NIASO_RS04895
uniprot id: W0EZZ2
names: Function
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.

929713:NIASO RS16320
gene id: 929713:NIASO_RS16320
uniprot id: W0F575
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.
messages: Homotrimer.

929713:NIASO RS14020
gene id: 929713:NIASO_RS14020
uniprot id: W0F2V0
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS12660
gene id: 929713:NIASO_RS12660
uniprot id: W0EYS3
names: Similarity
messages: Belongs to the AlaDH/PNT family.

929713:NIASO RS11105
gene id: 929713:NIASO_RS11105
uniprot id: W0EY23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease N1/T1 family.
messages: Secreted

929713:NIASO RS05955
gene id: 929713:NIASO_RS05955
uniprot id: W0EVR5
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

929713:NIASO RS07460
gene id: 929713:NIASO_RS07460
uniprot id: W0F1A8
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS01535
gene id: 929713:NIASO_RS01535
uniprot id: W0EYI4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

929713:NIASO RS18680
gene id: 929713:NIASO_RS18680
uniprot id: W0F5W4
names: Similarity
messages: Belongs to the FGGY kinase family.

929713:NIASO RS14375
gene id: 929713:NIASO_RS14375
uniprot id: W0F4D5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

929713:NIASO RS10655
gene id: 929713:NIASO_RS10655
uniprot id: W0F2R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

929713:NIASO RS14075
gene id: 929713:NIASO_RS14075
uniprot id: W0EZE3
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

929713:NIASO RS03545
gene id: 929713:NIASO_RS03545
uniprot id: W0EYA6
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

929713:NIASO RS07775
gene id: 929713:NIASO_RS07775
uniprot id: W0EWL2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

929713:NIASO RS00685
gene id: 929713:NIASO_RS00685
uniprot id: W0F5E3
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS01240
gene id: 929713:NIASO_RS01240
uniprot id: W0ETT1
names: Cofactor
messages: Binds 1 zinc ion per subunit.

929713:NIASO RS09160
gene id: 929713:NIASO_RS09160
uniprot id: W0F236
names: Caution
names: Function
names: Similarity
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).

929713:NIASO RS11260
gene id: 929713:NIASO_RS11260
uniprot id: W0EY40
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS09500
gene id: 929713:NIASO_RS09500
uniprot id: W0F1U1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

929713:NIASO RS11980
gene id: 929713:NIASO_RS11980
uniprot id: W0F2V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

929713:NIASO RS05230
gene id: 929713:NIASO_RS05230
uniprot id: W0EZ21
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS08450
gene id: 929713:NIASO_RS08450
uniprot id: W0EWT9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

929713:NIASO RS15865
gene id: 929713:NIASO_RS15865
uniprot id: W0F083
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

929713:NIASO RS11755
gene id: 929713:NIASO_RS11755
uniprot id: W0EYF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

929713:NIASO RS11845
gene id: 929713:NIASO_RS11845
uniprot id: W0EYB3
names: Similarity
messages: Belongs to the pirin family.

929713:NIASO RS15495
gene id: 929713:NIASO_RS15495
uniprot id: W0EZX8
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

929713:NIASO RS19370
gene id: 929713:NIASO_RS19370
uniprot id: W0F690
names: Cofactor
messages: Binds 1 zinc ion per subunit.

929713:NIASO RS15020
gene id: 929713:NIASO_RS15020
uniprot id: W0F3B9
names: Similarity
messages: Belongs to the sulfatase family.

929713:NIASO RS07465
gene id: 929713:NIASO_RS07465
uniprot id: W0EWH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS00185
gene id: 929713:NIASO_RS00185
uniprot id: W0EY68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

929713:NIASO RS08800
gene id: 929713:NIASO_RS08800
uniprot id: W0F0I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

929713:NIASO RS10285
gene id: 929713:NIASO_RS10285
uniprot id: W0EXM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

929713:NIASO RS18050
gene id: 929713:NIASO_RS18050
uniprot id: W0F193
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

929713:NIASO RS02430
gene id: 929713:NIASO_RS02430
uniprot id: W0EXU9
names: Similarity
messages: Belongs to the YciI family.

929713:NIASO RS06515
gene id: 929713:NIASO_RS06515
uniprot id: W0F0K9
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

929713:NIASO RS03670
gene id: 929713:NIASO_RS03670
uniprot id: W0EUX2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

929713:NIASO RS01450
gene id: 929713:NIASO_RS01450
uniprot id: W0EYH4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

929713:NIASO RS17185
gene id: 929713:NIASO_RS17185
uniprot id: W0F486
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

929713:NIASO RS10345
gene id: 929713:NIASO_RS10345
uniprot id: W0F2L5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

929713:NIASO RS09065
gene id: 929713:NIASO_RS09065
uniprot id: W0F1M5
names: Similarity
messages: Belongs to the CinA family.

929713:NIASO RS04085
gene id: 929713:NIASO_RS04085
uniprot id: W0EZW3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

929713:NIASO RS16380
gene id: 929713:NIASO_RS16380
uniprot id: W0F0G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

929713:NIASO RS18290
gene id: 929713:NIASO_RS18290
uniprot id: W0F628
names: Similarity
messages: Belongs to the phosphohexose mutase family.

929713:NIASO RS01095
gene id: 929713:NIASO_RS01095
uniprot id: W0ETV7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

929713:NIASO RS07945
gene id: 929713:NIASO_RS07945
uniprot id: W0EWN2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

929713:NIASO RS01220
gene id: 929713:NIASO_RS01220
uniprot id: W0EYP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

929713:NIASO RS06265
gene id: 929713:NIASO_RS06265
uniprot id: W0F0T0
names: Similarity
messages: Belongs to the SAICAR synthetase family.

929713:NIASO RS16835
gene id: 929713:NIASO_RS16835
uniprot id: W0F426
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

929713:NIASO RS07160
gene id: 929713:NIASO_RS07160
uniprot id: W0EWC0
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

929713:NIASO RS05085
gene id: 929713:NIASO_RS05085
uniprot id: W0EVF6
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

929713:NIASO RS02205
gene id: 929713:NIASO_RS02205
uniprot id: W0EXR2
names: Similarity
messages: Belongs to the AHA1 family.

929713:NIASO RS18780
gene id: 929713:NIASO_RS18780
uniprot id: W0F5Y7
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

929713:NIASO RS17930
gene id: 929713:NIASO_RS17930
uniprot id: W0F4M7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

929713:NIASO RS00110
gene id: 929713:NIASO_RS00110
uniprot id: W0ETD6
names: Similarity
messages: Belongs to the peptidase M1 family.

929713:NIASO RS17995
gene id: 929713:NIASO_RS17995
uniprot id: W0F5M1
names: Similarity
messages: Belongs to the DinB family.

929713:NIASO RS01375
gene id: 929713:NIASO_RS01375
uniprot id: W0EYR8
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

929713:NIASO RS01000
gene id: 929713:NIASO_RS01000
uniprot id: W0F1X9
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS13255
gene id: 929713:NIASO_RS13255
uniprot id: W0F3D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

929713:NIASO RS04195
gene id: 929713:NIASO_RS04195
uniprot id: W0EZP1
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

929713:NIASO RS15525
gene id: 929713:NIASO_RS15525
uniprot id: W0F4W3
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

929713:NIASO RS17400
gene id: 929713:NIASO_RS17400
uniprot id: W0F5D7
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS02555
gene id: 929713:NIASO_RS02555
uniprot id: W0EZ91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

929713:NIASO RS12640
gene id: 929713:NIASO_RS12640
uniprot id: W0F346
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

929713:NIASO RS17945
gene id: 929713:NIASO_RS17945
uniprot id: W0F5Y9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

929713:NIASO RS18675
gene id: 929713:NIASO_RS18675
uniprot id: W0F4Z4
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS16125
gene id: 929713:NIASO_RS16125
uniprot id: W0F080
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS04965
gene id: 929713:NIASO_RS04965
uniprot id: W0F0A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

929713:NIASO RS18835
gene id: 929713:NIASO_RS18835
uniprot id: W0F1F6
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

929713:NIASO RS07760
gene id: 929713:NIASO_RS07760
uniprot id: W0F035
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Cytoplasm

929713:NIASO RS13055
gene id: 929713:NIASO_RS13055
uniprot id: W0EYY2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

929713:NIASO RS12645
gene id: 929713:NIASO_RS12645
uniprot id: W0F432
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS02705
gene id: 929713:NIASO_RS02705
uniprot id: W0EXY3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

929713:NIASO RS02795
gene id: 929713:NIASO_RS02795
uniprot id: W0EUE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

929713:NIASO RS05720
gene id: 929713:NIASO_RS05720
uniprot id: W0EZ75
names: Similarity
messages: Belongs to the pirin family.

929713:NIASO RS02910
gene id: 929713:NIASO_RS02910
uniprot id: W0EZ43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

929713:NIASO RS05620
gene id: 929713:NIASO_RS05620
uniprot id: W0EVM9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

929713:NIASO RS07010
gene id: 929713:NIASO_RS07010
uniprot id: W0EW78
names: Similarity
messages: Belongs to the citrate synthase family.

929713:NIASO RS02325
gene id: 929713:NIASO_RS02325
uniprot id: W0EU76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

929713:NIASO RS07170
gene id: 929713:NIASO_RS07170
uniprot id: W0F0V4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

929713:NIASO RS11735
gene id: 929713:NIASO_RS11735
uniprot id: W0F1W5
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

929713:NIASO RS03970
gene id: 929713:NIASO_RS03970
uniprot id: W0EYI1
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS17070
gene id: 929713:NIASO_RS17070
uniprot id: W0F5J0
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

929713:NIASO RS18000
gene id: 929713:NIASO_RS18000
uniprot id: W0F137
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

929713:NIASO RS07335
gene id: 929713:NIASO_RS07335
uniprot id: W0EWD8
names: Similarity
messages: Belongs to the arginine deiminase family.

929713:NIASO RS07965
gene id: 929713:NIASO_RS07965
uniprot id: W0F195
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

929713:NIASO RS15040
gene id: 929713:NIASO_RS15040
uniprot id: W0F947
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

929713:NIASO RS03630
gene id: 929713:NIASO_RS03630
uniprot id: W0F2F8
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS02790
gene id: 929713:NIASO_RS02790
uniprot id: W0EZ20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

929713:NIASO RS12155
gene id: 929713:NIASO_RS12155
uniprot id: W0F228
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS08205
gene id: 929713:NIASO_RS08205
uniprot id: W0EWR4
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

929713:NIASO RS05950
gene id: 929713:NIASO_RS05950
uniprot id: W0F0C2
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

929713:NIASO RS00630
gene id: 929713:NIASO_RS00630
uniprot id: W0ETL7
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

929713:NIASO RS02970
gene id: 929713:NIASO_RS02970
uniprot id: W0EZ53
names: Similarity
messages: Belongs to the peptidase C56 family.

929713:NIASO RS18840
gene id: 929713:NIASO_RS18840
uniprot id: W0F6B7
names: Similarity
messages: Belongs to the sulfatase family.

929713:NIASO RS11130
gene id: 929713:NIASO_RS11130
uniprot id: W0EY28
names: Similarity
messages: Belongs to the DapB family.

929713:NIASO RS00075
gene id: 929713:NIASO_RS00075
uniprot id: W0EY48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

929713:NIASO RS02610
gene id: 929713:NIASO_RS02610
uniprot id: W0EUB8
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

929713:NIASO RS12735
gene id: 929713:NIASO_RS12735
uniprot id: W0F362
names: Similarity
messages: Belongs to the sulfatase family.

929713:NIASO RS13895
gene id: 929713:NIASO_RS13895
uniprot id: W0EZB1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

929713:NIASO RS05215
gene id: 929713:NIASO_RS05215
uniprot id: W0F785
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS17195
gene id: 929713:NIASO_RS17195
uniprot id: W0F5L9
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

929713:NIASO RS14950
gene id: 929713:NIASO_RS14950
uniprot id: W0EZU6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

929713:NIASO RS18860
gene id: 929713:NIASO_RS18860
uniprot id: W0F606
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

929713:NIASO RS04140
gene id: 929713:NIASO_RS04140
uniprot id: W0EZW8
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

929713:NIASO RS02070
gene id: 929713:NIASO_RS02070
uniprot id: W0EYQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

929713:NIASO RS08695
gene id: 929713:NIASO_RS08695
uniprot id: W0F1W3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

929713:NIASO RS05715
gene id: 929713:NIASO_RS05715
uniprot id: W0EVP1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

929713:NIASO RS07780
gene id: 929713:NIASO_RS07780
uniprot id: W0F1H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

929713:NIASO RS18115
gene id: 929713:NIASO_RS18115
uniprot id: W0F147
names: Similarity
messages: Belongs to the peptidase S66 family.

929713:NIASO RS03415
gene id: 929713:NIASO_RS03415
uniprot id: W0EUQ2
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

929713:NIASO RS06705
gene id: 929713:NIASO_RS06705
uniprot id: W0F0Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

929713:NIASO RS03515
gene id: 929713:NIASO_RS03515
uniprot id: W0EZD1
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS02900
gene id: 929713:NIASO_RS02900
uniprot id: W0EUJ6
names: Similarity
messages: Belongs to the UPF0758 family.

929713:NIASO RS09925
gene id: 929713:NIASO_RS09925
uniprot id: W0F2E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

929713:NIASO RS11630
gene id: 929713:NIASO_RS11630
uniprot id: W0F1U3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

929713:NIASO RS07385
gene id: 929713:NIASO_RS07385
uniprot id: W0EWF0
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

929713:NIASO RS15055
gene id: 929713:NIASO_RS15055
uniprot id: W0F4N6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

929713:NIASO RS11585
gene id: 929713:NIASO_RS11585
uniprot id: W0F2Q0
names: Cofactor
messages: Binds 1 zinc ion per subunit.

929713:NIASO RS04620
gene id: 929713:NIASO_RS04620
uniprot id: W0EVC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS05595
gene id: 929713:NIASO_RS05595
uniprot id: W0EZ57
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

929713:NIASO RS07040
gene id: 929713:NIASO_RS07040
uniprot id: W0F133
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

929713:NIASO RS08755
gene id: 929713:NIASO_RS08755
uniprot id: W0EWX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

929713:NIASO RS03605
gene id: 929713:NIASO_RS03605
uniprot id: W0EUW3
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

929713:NIASO RS00315
gene id: 929713:NIASO_RS00315
uniprot id: W0EY85
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

929713:NIASO RS01070
gene id: 929713:NIASO_RS01070
uniprot id: W0ETV3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

929713:NIASO RS10670
gene id: 929713:NIASO_RS10670
uniprot id: W0F2A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

929713:NIASO RS13560
gene id: 929713:NIASO_RS13560
uniprot id: W0F3X6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

929713:NIASO RS07215
gene id: 929713:NIASO_RS07215
uniprot id: W0EWC9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

929713:NIASO RS16370
gene id: 929713:NIASO_RS16370
uniprot id: W0F0B9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

929713:NIASO RS13945
gene id: 929713:NIASO_RS13945
uniprot id: W0EZ76
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

929713:NIASO RS02755
gene id: 929713:NIASO_RS02755
uniprot id: W0EUH2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

929713:NIASO RS09995
gene id: 929713:NIASO_RS09995
uniprot id: W0F213
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

929713:NIASO RS09630
gene id: 929713:NIASO_RS09630
uniprot id: W0F2A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS01585
gene id: 929713:NIASO_RS01585
uniprot id: W0EYV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS03730
gene id: 929713:NIASO_RS03730
uniprot id: W0EUV1
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

929713:NIASO RS19480
gene id: 929713:NIASO_RS19480
uniprot id: W0F6B1
names: Similarity
messages: Belongs to the peptidase S49 family.

929713:NIASO RS10400
gene id: 929713:NIASO_RS10400
uniprot id: W0F2M5
names: Similarity
messages: Belongs to the phosphosulfolactate synthase family.

929713:NIASO RS05320
gene id: 929713:NIASO_RS05320
uniprot id: W0EZ33
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS06765
gene id: 929713:NIASO_RS06765
uniprot id: W0F0Z2
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

929713:NIASO RS11120
gene id: 929713:NIASO_RS11120
uniprot id: W0F1L9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

929713:NIASO RS05140
gene id: 929713:NIASO_RS05140
uniprot id: W0EVG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

929713:NIASO RS02850
gene id: 929713:NIASO_RS02850
uniprot id: W0EUF8
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS03620
gene id: 929713:NIASO_RS03620
uniprot id: W0EUT6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

929713:NIASO RS16535
gene id: 929713:NIASO_RS16535
uniprot id: W0F3X8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

929713:NIASO RS04205
gene id: 929713:NIASO_RS04205
uniprot id: W0EZZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

929713:NIASO RS00500
gene id: 929713:NIASO_RS00500
uniprot id: W0ETE2
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS04770
gene id: 929713:NIASO_RS04770
uniprot id: W0EVD9
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS09205
gene id: 929713:NIASO_RS09205
uniprot id: W0F1P6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

929713:NIASO RS02760
gene id: 929713:NIASO_RS02760
uniprot id: W0EXZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

929713:NIASO RS08600
gene id: 929713:NIASO_RS08600
uniprot id: W0F0F4
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

929713:NIASO RS05765
gene id: 929713:NIASO_RS05765
uniprot id: W0F0L0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

929713:NIASO RS01505
gene id: 929713:NIASO_RS01505
uniprot id: W0EYI2
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

929713:NIASO RS12050
gene id: 929713:NIASO_RS12050
uniprot id: W0EYJ0
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS03055
gene id: 929713:NIASO_RS03055
uniprot id: W0EZF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the high-potential iron-sulfur protein (HiPIP) family.
messages: Homodimer.
messages: Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria.

929713:NIASO RS00070
gene id: 929713:NIASO_RS00070
uniprot id: W0ET67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

929713:NIASO RS14865
gene id: 929713:NIASO_RS14865
uniprot id: W0EZT2
names: Similarity
messages: Belongs to the glycosyl hydrolase.

929713:NIASO RS04565
gene id: 929713:NIASO_RS04565
uniprot id: W0F058
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

929713:NIASO RS02085
gene id: 929713:NIASO_RS02085
uniprot id: W0EU84
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

929713:NIASO RS05795
gene id: 929713:NIASO_RS05795
uniprot id: W0EVQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

929713:NIASO RS09350
gene id: 929713:NIASO_RS09350
uniprot id: W0F0S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

929713:NIASO RS01985
gene id: 929713:NIASO_RS01985
uniprot id: W0EYP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

929713:NIASO RS01900
gene id: 929713:NIASO_RS01900
uniprot id: W0EYM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

929713:NIASO RS17515
gene id: 929713:NIASO_RS17515
uniprot id: W0F121
names: Similarity
messages: Belongs to the glutamate synthase family.

929713:NIASO RS03870
gene id: 929713:NIASO_RS03870
uniprot id: W0EV05
names: Similarity
messages: Belongs to the DapA family.

929713:NIASO RS18470
gene id: 929713:NIASO_RS18470
uniprot id: W0F649
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

929713:NIASO RS06950
gene id: 929713:NIASO_RS06950
uniprot id: W0EW72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Membrane

929713:NIASO RS15900
gene id: 929713:NIASO_RS15900
uniprot id: W0F3Q2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

929713:NIASO RS07635
gene id: 929713:NIASO_RS07635
uniprot id: W0F1G0
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS14130
gene id: 929713:NIASO_RS14130
uniprot id: W0F2W4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

929713:NIASO RS12710
gene id: 929713:NIASO_RS12710
uniprot id: W0EYN7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

929713:NIASO RS02915
gene id: 929713:NIASO_RS02915
uniprot id: W0EUH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

929713:NIASO RS04550
gene id: 929713:NIASO_RS04550
uniprot id: W0EYT9
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS16915
gene id: 929713:NIASO_RS16915
uniprot id: W0F0Q4
names: Subcellular Location Annotation
messages: Cytoplasm

929713:NIASO RS01075
gene id: 929713:NIASO_RS01075
uniprot id: W0EXB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

929713:NIASO RS02075
gene id: 929713:NIASO_RS02075
uniprot id: W0EU42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

929713:NIASO RS08250
gene id: 929713:NIASO_RS08250
uniprot id: W0F1D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

929713:NIASO RS18140
gene id: 929713:NIASO_RS18140
uniprot id: W0F5N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

929713:NIASO RS06900
gene id: 929713:NIASO_RS06900
uniprot id: W0F113
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS04220
gene id: 929713:NIASO_RS04220
uniprot id: W0EYN9
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS01005
gene id: 929713:NIASO_RS01005
uniprot id: W0EXA1
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS13085
gene id: 929713:NIASO_RS13085
uniprot id: W0F2E5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

929713:NIASO RS00880
gene id: 929713:NIASO_RS00880
uniprot id: W0ETK7
names: Similarity
messages: Belongs to the DEAD box helicase family.

929713:NIASO RS14230
gene id: 929713:NIASO_RS14230
uniprot id: W0EZD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS01680
gene id: 929713:NIASO_RS01680
uniprot id: W0ETY2
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

929713:NIASO RS01690
gene id: 929713:NIASO_RS01690
uniprot id: W0EU25
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

929713:NIASO RS17485
gene id: 929713:NIASO_RS17485
uniprot id: W0F5S2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

929713:NIASO RS05005
gene id: 929713:NIASO_RS05005
uniprot id: W0EYZ3
names: Similarity
messages: Belongs to the aspartokinase family.

929713:NIASO RS17955
gene id: 929713:NIASO_RS17955
uniprot id: W0F177
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

929713:NIASO RS13270
gene id: 929713:NIASO_RS13270
uniprot id: W0EZ18
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS05945
gene id: 929713:NIASO_RS05945
uniprot id: W0EZA9
names: Similarity
messages: Belongs to the aldose epimerase family.

929713:NIASO RS13870
gene id: 929713:NIASO_RS13870
uniprot id: W0F2S3
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS08155
gene id: 929713:NIASO_RS08155
uniprot id: W0F093
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

929713:NIASO RS12680
gene id: 929713:NIASO_RS12680
uniprot id: W0F3N8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS20485
gene id: 929713:NIASO_RS20485
uniprot id: W0EUE4
names: Similarity
messages: Belongs to the AHA1 family.

929713:NIASO RS02785
gene id: 929713:NIASO_RS02785
uniprot id: W0EXZ5
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

929713:NIASO RS09135
gene id: 929713:NIASO_RS09135
uniprot id: W0F231
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

929713:NIASO RS13860
gene id: 929713:NIASO_RS13860
uniprot id: W0EZA4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

929713:NIASO RS03775
gene id: 929713:NIASO_RS03775
uniprot id: W0EUV6
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS05080
gene id: 929713:NIASO_RS05080
uniprot id: W0F009
names: Similarity
messages: Belongs to the peptidase M1 family.

929713:NIASO RS14070
gene id: 929713:NIASO_RS14070
uniprot id: W0F452
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS10945
gene id: 929713:NIASO_RS10945
uniprot id: W0F1I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

929713:NIASO RS07060
gene id: 929713:NIASO_RS07060
uniprot id: W0F0T6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

929713:NIASO RS04215
gene id: 929713:NIASO_RS04215
uniprot id: W0EV70
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

929713:NIASO RS03555
gene id: 929713:NIASO_RS03555
uniprot id: W0EUS4
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

929713:NIASO RS18110
gene id: 929713:NIASO_RS18110
uniprot id: W0F5N3
names: Similarity
messages: Belongs to the peptidase S66 family.

929713:NIASO RS10590
gene id: 929713:NIASO_RS10590
uniprot id: W0F291
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS09945
gene id: 929713:NIASO_RS09945
uniprot id: W0EXG5
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

929713:NIASO RS18155
gene id: 929713:NIASO_RS18155
uniprot id: W0F1A5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS09340
gene id: 929713:NIASO_RS09340
uniprot id: W0F268
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

929713:NIASO RS16825
gene id: 929713:NIASO_RS16825
uniprot id: W0F5E7
names: Similarity
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.

929713:NIASO RS10695
gene id: 929713:NIASO_RS10695
uniprot id: W0F2A9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

929713:NIASO RS12515
gene id: 929713:NIASO_RS12515
uniprot id: W0F3L9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

929713:NIASO RS12170
gene id: 929713:NIASO_RS12170
uniprot id: W0F3G6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS01360
gene id: 929713:NIASO_RS01360
uniprot id: W0ETU2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

929713:NIASO RS07875
gene id: 929713:NIASO_RS07875
uniprot id: W0EWM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

929713:NIASO RS11300
gene id: 929713:NIASO_RS11300
uniprot id: W0F2L2
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS17605
gene id: 929713:NIASO_RS17605
uniprot id: W0F131
names: Similarity
messages: Belongs to the sulfatase family.

929713:NIASO RS08950
gene id: 929713:NIASO_RS08950
uniprot id: W0F1Z9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

929713:NIASO RS02220
gene id: 929713:NIASO_RS02220
uniprot id: W0EU57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

929713:NIASO RS16910
gene id: 929713:NIASO_RS16910
uniprot id: W0F5G1
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS01415
gene id: 929713:NIASO_RS01415
uniprot id: W0EXF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

929713:NIASO RS18850
gene id: 929713:NIASO_RS18850
uniprot id: W0F524
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS17260
gene id: 929713:NIASO_RS17260
uniprot id: W0F5N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

929713:NIASO RS18060
gene id: 929713:NIASO_RS18060
uniprot id: W0F5M9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS17135
gene id: 929713:NIASO_RS17135
uniprot id: W0F0P4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

929713:NIASO RS07630
gene id: 929713:NIASO_RS07630
uniprot id: W0EWJ7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

929713:NIASO RS00765
gene id: 929713:NIASO_RS00765
uniprot id: W0EX33
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

929713:NIASO RS18195
gene id: 929713:NIASO_RS18195
uniprot id: W0F5P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

929713:NIASO RS18735
gene id: 929713:NIASO_RS18735
uniprot id: H1NKL3
names: Similarity
messages: Belongs to the DapA family.

929713:NIASO RS14900
gene id: 929713:NIASO_RS14900
uniprot id: W0F488
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS18070
gene id: 929713:NIASO_RS18070
uniprot id: W0F144
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

929713:NIASO RS17820
gene id: 929713:NIASO_RS17820
uniprot id: W0F4V0
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS04200
gene id: 929713:NIASO_RS04200
uniprot id: W0EV44
names: Caution
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

929713:NIASO RS09890
gene id: 929713:NIASO_RS09890
uniprot id: W0F1Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

929713:NIASO RS07970
gene id: 929713:NIASO_RS07970
uniprot id: W0EWN7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

929713:NIASO RS06235
gene id: 929713:NIASO_RS06235
uniprot id: W0F0S4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

929713:NIASO RS01855
gene id: 929713:NIASO_RS01855
uniprot id: W0EU50
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS09050
gene id: 929713:NIASO_RS09050
uniprot id: W0F215
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS11910
gene id: 929713:NIASO_RS11910
uniprot id: W0F2U3
names: Similarity
messages: Belongs to the HSP15 family.

929713:NIASO RS15120
gene id: 929713:NIASO_RS15120
uniprot id: W0F3C8
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS02805
gene id: 929713:NIASO_RS02805
uniprot id: W0EUI2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

929713:NIASO RS10450
gene id: 929713:NIASO_RS10450
uniprot id: W0EXV6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

929713:NIASO RS06415
gene id: 929713:NIASO_RS06415
uniprot id: W0EVX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS01100
gene id: 929713:NIASO_RS01100
uniprot id: W0EXB6
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

929713:NIASO RS11705
gene id: 929713:NIASO_RS11705
uniprot id: W0F1W0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS08780
gene id: 929713:NIASO_RS08780
uniprot id: W0EWY1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

929713:NIASO RS09585
gene id: 929713:NIASO_RS09585
uniprot id: W0EX99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

929713:NIASO RS00395
gene id: 929713:NIASO_RS00395
uniprot id: W0EYA1
names: Similarity
messages: Belongs to the aspartokinase family.

929713:NIASO RS12330
gene id: 929713:NIASO_RS12330
uniprot id: W0EYI0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS06215
gene id: 929713:NIASO_RS06215
uniprot id: W0EZE1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

929713:NIASO RS02640
gene id: 929713:NIASO_RS02640
uniprot id: W0EXX5
names: Similarity
messages: Belongs to the UbiD family.

929713:NIASO RS03625
gene id: 929713:NIASO_RS03625
uniprot id: W0EZN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

929713:NIASO RS14680
gene id: 929713:NIASO_RS14680
uniprot id: W0F374
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS17665
gene id: 929713:NIASO_RS17665
uniprot id: W0F4I6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS15535
gene id: 929713:NIASO_RS15535
uniprot id: W0F3J6
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

929713:NIASO RS06075
gene id: 929713:NIASO_RS06075
uniprot id: W0EZD0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

929713:NIASO RS19460
gene id: 929713:NIASO_RS19460
uniprot id: W0F1Q2
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

929713:NIASO RS04035
gene id: 929713:NIASO_RS04035
uniprot id: W0EZK6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

929713:NIASO RS10165
gene id: 929713:NIASO_RS10165
uniprot id: W0F140
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

929713:NIASO RS10520
gene id: 929713:NIASO_RS10520
uniprot id: W0EXW2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS06695
gene id: 929713:NIASO_RS06695
uniprot id: W0F0N2
names: Similarity
messages: Belongs to the SufE family.

929713:NIASO RS08995
gene id: 929713:NIASO_RS08995
uniprot id: W0EX59
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

929713:NIASO RS06370
gene id: 929713:NIASO_RS06370
uniprot id: W0F0U4
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

929713:NIASO RS01975
gene id: 929713:NIASO_RS01975
uniprot id: W0EU70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

929713:NIASO RS08045
gene id: 929713:NIASO_RS08045
uniprot id: W0F079
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

929713:NIASO RS04355
gene id: 929713:NIASO_RS04355
uniprot id: W0EZS5
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

929713:NIASO RS12760
gene id: 929713:NIASO_RS12760
uniprot id: W0F3Y0
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS00120
gene id: 929713:NIASO_RS00120
uniprot id: W0F1R8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

929713:NIASO RS14335
gene id: 929713:NIASO_RS14335
uniprot id: W0F315
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

929713:NIASO RS10260
gene id: 929713:NIASO_RS10260
uniprot id: W0EXS8
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS02725
gene id: 929713:NIASO_RS02725
uniprot id: W0EUG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

929713:NIASO RS13345
gene id: 929713:NIASO_RS13345
uniprot id: W0F3U9
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

929713:NIASO RS09040
gene id: 929713:NIASO_RS09040
uniprot id: W0EX21
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

929713:NIASO RS05900
gene id: 929713:NIASO_RS05900
uniprot id: W0EVR6
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

929713:NIASO RS15595
gene id: 929713:NIASO_RS15595
uniprot id: W0F4X5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS18220
gene id: 929713:NIASO_RS18220
uniprot id: W0F4S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

929713:NIASO RS08355
gene id: 929713:NIASO_RS08355
uniprot id: W0EWT3
names: Similarity
messages: Belongs to the peptidase M13 family.

929713:NIASO RS11000
gene id: 929713:NIASO_RS11000
uniprot id: W0F1J7
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

929713:NIASO RS18555
gene id: 929713:NIASO_RS18555
uniprot id: W0F1A7
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

929713:NIASO RS16385
gene id: 929713:NIASO_RS16385
uniprot id: W0F3V5
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS18905
gene id: 929713:NIASO_RS18905
uniprot id: W0F1L7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

929713:NIASO RS02600
gene id: 929713:NIASO_RS02600
uniprot id: W0EXX0
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

929713:NIASO RS07695
gene id: 929713:NIASO_RS07695
uniprot id: W0F158
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

929713:NIASO RS01965
gene id: 929713:NIASO_RS01965
uniprot id: W0EU24
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS11920
gene id: 929713:NIASO_RS11920
uniprot id: W0F3D4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

929713:NIASO RS13200
gene id: 929713:NIASO_RS13200
uniprot id: W0F3C7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

929713:NIASO RS12570
gene id: 929713:NIASO_RS12570
uniprot id: W0F335
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

929713:NIASO RS18945
gene id: 929713:NIASO_RS18945
uniprot id: W0F1H2
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS15315
gene id: 929713:NIASO_RS15315
uniprot id: W0F4E0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

929713:NIASO RS16510
gene id: 929713:NIASO_RS16510
uniprot id: W0F4Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

929713:NIASO RS00330
gene id: 929713:NIASO_RS00330
uniprot id: W0EXY4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

929713:NIASO RS10465
gene id: 929713:NIASO_RS10465
uniprot id: W0F185
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

929713:NIASO RS16960
gene id: 929713:NIASO_RS16960
uniprot id: W0F0L5
names: Similarity
messages: Belongs to the pirin family.

929713:NIASO RS17000
gene id: 929713:NIASO_RS17000
uniprot id: W0F0S0
names: Similarity
messages: Belongs to the DprA/Smf family.

929713:NIASO RS03430
gene id: 929713:NIASO_RS03430
uniprot id: W0EY91
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

929713:NIASO RS04040
gene id: 929713:NIASO_RS04040
uniprot id: W0EV08
names: Similarity
messages: Belongs to the IMPACT family.

929713:NIASO RS08775
gene id: 929713:NIASO_RS08775
uniprot id: W0F1I8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

929713:NIASO RS07255
gene id: 929713:NIASO_RS07255
uniprot id: W0F0W8
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS18035
gene id: 929713:NIASO_RS18035
uniprot id: W0F5M5
names: Similarity
messages: Belongs to the bleomycin resistance protein family.

929713:NIASO RS17925
gene id: 929713:NIASO_RS17925
uniprot id: W0F172
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

929713:NIASO RS01210
gene id: 929713:NIASO_RS01210
uniprot id: W0EYD8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated Cas9 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.
messages: Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.
messages: Monomer. Binds crRNA and tracrRNA.

929713:NIASO RS17845
gene id: 929713:NIASO_RS17845
uniprot id: W0F117
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

929713:NIASO RS17915
gene id: 929713:NIASO_RS17915
uniprot id: W0F126
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

929713:NIASO RS11320
gene id: 929713:NIASO_RS11320
uniprot id: W0EY95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Belongs to the heat shock protein 70 family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

929713:NIASO RS17450
gene id: 929713:NIASO_RS17450
uniprot id: W0F869
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

929713:NIASO RS19035
gene id: 929713:NIASO_RS19035
uniprot id: W0F1I6
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

929713:NIASO RS12245
gene id: 929713:NIASO_RS12245
uniprot id: W0F241
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

929713:NIASO RS07475
gene id: 929713:NIASO_RS07475
uniprot id: W0F100
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS16855
gene id: 929713:NIASO_RS16855
uniprot id: W0F0P5
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

929713:NIASO RS02765
gene id: 929713:NIASO_RS02765
uniprot id: W0EZ14
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS16690
gene id: 929713:NIASO_RS16690
uniprot id: W0F0H1
names: Similarity
messages: Belongs to the YicC/YloC family.

929713:NIASO RS08190
gene id: 929713:NIASO_RS08190
uniprot id: W0F098
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS05435
gene id: 929713:NIASO_RS05435
uniprot id: W0F0G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

929713:NIASO RS12685
gene id: 929713:NIASO_RS12685
uniprot id: W0EYS7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

929713:NIASO RS19420
gene id: 929713:NIASO_RS19420
uniprot id: W0F596
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

929713:NIASO RS07820
gene id: 929713:NIASO_RS07820
uniprot id: W0F175
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

929713:NIASO RS00920
gene id: 929713:NIASO_RS00920
uniprot id: W0EYJ4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

929713:NIASO RS12120
gene id: 929713:NIASO_RS12120
uniprot id: W0F3F8
names: Similarity
messages: Belongs to the AHA1 family.

929713:NIASO RS12080
gene id: 929713:NIASO_RS12080
uniprot id: W0EYJ5
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

929713:NIASO RS09005
gene id: 929713:NIASO_RS09005
uniprot id: W0F1L5
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

929713:NIASO RS19510
gene id: 929713:NIASO_RS19510
uniprot id: W0F5A6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

929713:NIASO RS10685
gene id: 929713:NIASO_RS10685
uniprot id: W0EXZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

929713:NIASO RS13800
gene id: 929713:NIASO_RS13800
uniprot id: W0F3M0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS15650
gene id: 929713:NIASO_RS15650
uniprot id: W0F048
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

929713:NIASO RS07095
gene id: 929713:NIASO_RS07095
uniprot id: W0F142
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

929713:NIASO RS07790
gene id: 929713:NIASO_RS07790
uniprot id: W0F040
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

929713:NIASO RS01265
gene id: 929713:NIASO_RS01265
uniprot id: W0EXD6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

929713:NIASO RS10020
gene id: 929713:NIASO_RS10020
uniprot id: W0F115
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

929713:NIASO RS01290
gene id: 929713:NIASO_RS01290
uniprot id: W0EYQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

929713:NIASO RS12295
gene id: 929713:NIASO_RS12295
uniprot id: W0EYH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

929713:NIASO RS16065
gene id: 929713:NIASO_RS16065
uniprot id: W0F067
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS10075
gene id: 929713:NIASO_RS10075
uniprot id: W0EXP2
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS07860
gene id: 929713:NIASO_RS07860
uniprot id: W0EWR3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

929713:NIASO RS10660
gene id: 929713:NIASO_RS10660
uniprot id: W0EXY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

929713:NIASO RS14195
gene id: 929713:NIASO_RS14195
uniprot id: W0F2X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

929713:NIASO RS07245
gene id: 929713:NIASO_RS07245
uniprot id: W0EWD6
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

929713:NIASO RS10600
gene id: 929713:NIASO_RS10600
uniprot id: W0F2Q2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

929713:NIASO RS18120
gene id: 929713:NIASO_RS18120
uniprot id: W0F607
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS15625
gene id: 929713:NIASO_RS15625
uniprot id: W0F043
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

929713:NIASO RS07840
gene id: 929713:NIASO_RS07840
uniprot id: W0F050
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

929713:NIASO RS08910
gene id: 929713:NIASO_RS08910
uniprot id: W0F0J9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

929713:NIASO RS06880
gene id: 929713:NIASO_RS06880
uniprot id: W0F0R2
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS10935
gene id: 929713:NIASO_RS10935
uniprot id: W0EY49
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

929713:NIASO RS16845
gene id: 929713:NIASO_RS16845
uniprot id: W0F0J5
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

929713:NIASO RS07750
gene id: 929713:NIASO_RS07750
uniprot id: W0EWP3
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

929713:NIASO RS05760
gene id: 929713:NIASO_RS05760
uniprot id: W0EVN6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

929713:NIASO RS14525
gene id: 929713:NIASO_RS14525
uniprot id: W0F435
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS09000
gene id: 929713:NIASO_RS09000
uniprot id: W0F0L3
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

929713:NIASO RS19080
gene id: 929713:NIASO_RS19080
uniprot id: W0F6F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

929713:NIASO RS01455
gene id: 929713:NIASO_RS01455
uniprot id: W0ETV4
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS11395
gene id: 929713:NIASO_RS11395
uniprot id: W0F2M6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

929713:NIASO RS06855
gene id: 929713:NIASO_RS06855
uniprot id: W0F324
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS17370
gene id: 929713:NIASO_RS17370
uniprot id: W0F4D0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

929713:NIASO RS06805
gene id: 929713:NIASO_RS06805
uniprot id: W0F0Q3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS11295
gene id: 929713:NIASO_RS11295
uniprot id: W0F1P5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

929713:NIASO RS03175
gene id: 929713:NIASO_RS03175
uniprot id: W0F2G2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

929713:NIASO RS02960
gene id: 929713:NIASO_RS02960
uniprot id: W0EY22
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

929713:NIASO RS18135
gene id: 929713:NIASO_RS18135
uniprot id: W0F4Q7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

929713:NIASO RS14565
gene id: 929713:NIASO_RS14565
uniprot id: W0EZP5
names: Similarity
messages: Belongs to the sulfatase family.

929713:NIASO RS11665
gene id: 929713:NIASO_RS11665
uniprot id: W0EY88
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

929713:NIASO RS18095
gene id: 929713:NIASO_RS18095
uniprot id: W0F4Q2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS14875
gene id: 929713:NIASO_RS14875
uniprot id: W0F484
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

929713:NIASO RS01420
gene id: 929713:NIASO_RS01420
uniprot id: W0EYG9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

929713:NIASO RS16465
gene id: 929713:NIASO_RS16465
uniprot id: W0F597
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

929713:NIASO RS08850
gene id: 929713:NIASO_RS08850
uniprot id: W0F0J4
names: Similarity
messages: Belongs to the UPF0102 family.

929713:NIASO RS11205
gene id: 929713:NIASO_RS11205
uniprot id: W0F322
names: Similarity
messages: Belongs to the peptidase C40 family.

929713:NIASO RS17890
gene id: 929713:NIASO_RS17890
uniprot id: W0F5Y0
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

929713:NIASO RS04150
gene id: 929713:NIASO_RS04150
uniprot id: W0EYK4
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

929713:NIASO RS13445
gene id: 929713:NIASO_RS13445
uniprot id: W0EYZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

929713:NIASO RS17600
gene id: 929713:NIASO_RS17600
uniprot id: W0F879
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

929713:NIASO RS18480
gene id: 929713:NIASO_RS18480
uniprot id: W0F4W0
names: Subcellular Location Annotation
messages: Secreted

929713:NIASO RS05845
gene id: 929713:NIASO_RS05845
uniprot id: W0F0M5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

929713:NIASO RS17595
gene id: 929713:NIASO_RS17595
uniprot id: W0F5U1
names: Similarity
messages: Belongs to the sulfatase family.

929713:NIASO RS00510
gene id: 929713:NIASO_RS00510
uniprot id: W0ETK3
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS00340
gene id: 929713:NIASO_RS00340
uniprot id: W0EY90
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

929713:NIASO RS16930
gene id: 929713:NIASO_RS16930
uniprot id: W0F540
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

929713:NIASO RS15455
gene id: 929713:NIASO_RS15455
uniprot id: W0F012
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS07445
gene id: 929713:NIASO_RS07445
uniprot id: W0F0Z5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS15550
gene id: 929713:NIASO_RS15550
uniprot id: W0EZY8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

929713:NIASO RS12825
gene id: 929713:NIASO_RS12825
uniprot id: W0EYQ3
names: Similarity
messages: Belongs to the peptidase C1 family.

929713:NIASO RS17410
gene id: 929713:NIASO_RS17410
uniprot id: W0F5R4
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

929713:NIASO RS10645
gene id: 929713:NIASO_RS10645
uniprot id: W0F2A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

929713:NIASO RS06710
gene id: 929713:NIASO_RS06710
uniprot id: W0EW40
names: Similarity
messages: Belongs to the sulfatase family.

929713:NIASO RS13970
gene id: 929713:NIASO_RS13970
uniprot id: W0F3P7
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS17735
gene id: 929713:NIASO_RS17735
uniprot id: W0F148
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

929713:NIASO RS09790
gene id: 929713:NIASO_RS09790
uniprot id: W0F2C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS05260
gene id: 929713:NIASO_RS05260
uniprot id: W0F031
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

929713:NIASO RS10470
gene id: 929713:NIASO_RS10470
uniprot id: W0F279
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

929713:NIASO RS05020
gene id: 929713:NIASO_RS05020
uniprot id: W0F0B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

929713:NIASO RS12790
gene id: 929713:NIASO_RS12790
uniprot id: W0EYP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

929713:NIASO RS18215
gene id: 929713:NIASO_RS18215
uniprot id: W0F1B3
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

929713:NIASO RS16085
gene id: 929713:NIASO_RS16085
uniprot id: W0F3S4
names: Similarity
messages: Belongs to the DapA family.

929713:NIASO RS14060
gene id: 929713:NIASO_RS14060
uniprot id: W0F8Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS03375
gene id: 929713:NIASO_RS03375
uniprot id: W0F2H2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

929713:NIASO RS02320
gene id: 929713:NIASO_RS02320
uniprot id: W0EYU1
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS00755
gene id: 929713:NIASO_RS00755
uniprot id: W0EYF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

929713:NIASO RS15695
gene id: 929713:NIASO_RS15695
uniprot id: W0F3M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

929713:NIASO RS16895
gene id: 929713:NIASO_RS16895
uniprot id: W0F536
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

929713:NIASO RS09030
gene id: 929713:NIASO_RS09030
uniprot id: W0F0L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

929713:NIASO RS15945
gene id: 929713:NIASO_RS15945
uniprot id: W0F046
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

929713:NIASO RS01805
gene id: 929713:NIASO_RS01805
uniprot id: W0EU40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS00105
gene id: 929713:NIASO_RS00105
uniprot id: W0EY53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

929713:NIASO RS13230
gene id: 929713:NIASO_RS13230
uniprot id: W0F3D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

929713:NIASO RS17480
gene id: 929713:NIASO_RS17480
uniprot id: W0F0X3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

929713:NIASO RS14405
gene id: 929713:NIASO_RS14405
uniprot id: W0EZH7
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

929713:NIASO RS11400
gene id: 929713:NIASO_RS11400
uniprot id: W0EY55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

929713:NIASO RS03455
gene id: 929713:NIASO_RS03455
uniprot id: W0EY97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

929713:NIASO RS08360
gene id: 929713:NIASO_RS08360
uniprot id: W0F1S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

929713:NIASO RS07285
gene id: 929713:NIASO_RS07285
uniprot id: W0F176
names: Similarity
messages: Belongs to the IlvD/Edd family.

929713:NIASO RS01400
gene id: 929713:NIASO_RS01400
uniprot id: W0ETU7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

929713:NIASO RS05105
gene id: 929713:NIASO_RS05105
uniprot id: W0F2P9
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

929713:NIASO RS12235
gene id: 929713:NIASO_RS12235
uniprot id: W0EYL1
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

929713:NIASO RS09295
gene id: 929713:NIASO_RS09295
uniprot id: W0EX64
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

929713:NIASO RS14620
gene id: 929713:NIASO_RS14620
uniprot id: W0EZQ1
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

929713:NIASO RS01045
gene id: 929713:NIASO_RS01045
uniprot id: W0ETU6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

929713:NIASO RS09305
gene id: 929713:NIASO_RS09305
uniprot id: W0EXA7
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

929713:NIASO RS09150
gene id: 929713:NIASO_RS09150
uniprot id: W0F1N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

929713:NIASO RS03015
gene id: 929713:NIASO_RS03015
uniprot id: W0EUI8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

929713:NIASO RS07800
gene id: 929713:NIASO_RS07800
uniprot id: W0EWL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

929713:NIASO RS12975
gene id: 929713:NIASO_RS12975
uniprot id: W0EYS2
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS12930
gene id: 929713:NIASO_RS12930
uniprot id: W0F2C5
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS03105
gene id: 929713:NIASO_RS03105
uniprot id: W0EZG5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

929713:NIASO RS15825
gene id: 929713:NIASO_RS15825
uniprot id: W0F512
names: Similarity
messages: Belongs to the Nth/MutY family.

929713:NIASO RS13565
gene id: 929713:NIASO_RS13565
uniprot id: W0EZ60
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS08620
gene id: 929713:NIASO_RS08620
uniprot id: W0EWV9
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

929713:NIASO RS09885
gene id: 929713:NIASO_RS09885
uniprot id: W0F0Y9
names: Similarity
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

929713:NIASO RS18920
gene id: 929713:NIASO_RS18920
uniprot id: W0F1G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

929713:NIASO RS04970
gene id: 929713:NIASO_RS04970
uniprot id: W0EVF9
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

929713:NIASO RS08325
gene id: 929713:NIASO_RS08325
uniprot id: W0EWS9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

929713:NIASO RS14840
gene id: 929713:NIASO_RS14840
uniprot id: W0F493
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS06310
gene id: 929713:NIASO_RS06310
uniprot id: W0EZF3
names: Similarity
messages: Belongs to the AHA1 family.

929713:NIASO RS17830
gene id: 929713:NIASO_RS17830
uniprot id: W0F160
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

929713:NIASO RS01065
gene id: 929713:NIASO_RS01065
uniprot id: W0EYM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

929713:NIASO RS06425
gene id: 929713:NIASO_RS06425
uniprot id: W0F0V2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

929713:NIASO RS04865
gene id: 929713:NIASO_RS04865
uniprot id: W0F7G6
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS07785
gene id: 929713:NIASO_RS07785
uniprot id: W0EWP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

929713:NIASO RS16565
gene id: 929713:NIASO_RS16565
uniprot id: W0F0J6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

929713:NIASO RS03345
gene id: 929713:NIASO_RS03345
uniprot id: W0F783
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

929713:NIASO RS15655
gene id: 929713:NIASO_RS15655
uniprot id: W0F3L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

929713:NIASO RS10265
gene id: 929713:NIASO_RS10265
uniprot id: W0F8B7
names: Similarity
messages: Belongs to the Skp family.

929713:NIASO RS17020
gene id: 929713:NIASO_RS17020
uniprot id: W0F5I4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

929713:NIASO RS17010
gene id: 929713:NIASO_RS17010
uniprot id: W0F553
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

929713:NIASO RS04400
gene id: 929713:NIASO_RS04400
uniprot id: W0EYR7
names: Subcellular Location Annotation
messages: Nucleus

929713:NIASO RS16460
gene id: 929713:NIASO_RS16460
uniprot id: W0F0D6
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

929713:NIASO RS19095
gene id: 929713:NIASO_RS19095
uniprot id: W0F655
names: Subcellular Location Annotation
messages: Cytoplasm

929713:NIASO RS02305
gene id: 929713:NIASO_RS02305
uniprot id: W0EZ54
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

929713:NIASO RS12895
gene id: 929713:NIASO_RS12895
uniprot id: W0F8T0
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS18965
gene id: 929713:NIASO_RS18965
uniprot id: W0F542
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS11775
gene id: 929713:NIASO_RS11775
uniprot id: W0F3B3
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

929713:NIASO RS01460
gene id: 929713:NIASO_RS01460
uniprot id: W0EYT1
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

929713:NIASO RS17325
gene id: 929713:NIASO_RS17325
uniprot id: W0F4S6
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

929713:NIASO RS07845
gene id: 929713:NIASO_RS07845
uniprot id: W0F178
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

929713:NIASO RS10270
gene id: 929713:NIASO_RS10270
uniprot id: W0F156
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

929713:NIASO RS04015
gene id: 929713:NIASO_RS04015
uniprot id: W0EV03
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

929713:NIASO RS10115
gene id: 929713:NIASO_RS10115
uniprot id: W0F230
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

929713:NIASO RS03535
gene id: 929713:NIASO_RS03535
uniprot id: W0EZM5
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

929713:NIASO RS00180
gene id: 929713:NIASO_RS00180
uniprot id: W0ET83
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS01435
gene id: 929713:NIASO_RS01435
uniprot id: W0EYS6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

929713:NIASO RS15750
gene id: 929713:NIASO_RS15750
uniprot id: W0F3N0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

929713:NIASO RS00355
gene id: 929713:NIASO_RS00355
uniprot id: W0EXY8
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS01245
gene id: 929713:NIASO_RS01245
uniprot id: W0EYQ0
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS14065
gene id: 929713:NIASO_RS14065
uniprot id: W0EZ97
names: Similarity
messages: Belongs to the UPF0111 family.

929713:NIASO RS02280
gene id: 929713:NIASO_RS02280
uniprot id: W0EUA4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

929713:NIASO RS17860
gene id: 929713:NIASO_RS17860
uniprot id: W0F164
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

929713:NIASO RS08120
gene id: 929713:NIASO_RS08120
uniprot id: W0EWQ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

929713:NIASO RS09920
gene id: 929713:NIASO_RS09920
uniprot id: W0EXG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

929713:NIASO RS17380
gene id: 929713:NIASO_RS17380
uniprot id: W0F0W1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

929713:NIASO RS01755
gene id: 929713:NIASO_RS01755
uniprot id: W0EXK1
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS17305
gene id: 929713:NIASO_RS17305
uniprot id: W0F0W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS08080
gene id: 929713:NIASO_RS08080
uniprot id: W0F084
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS09835
gene id: 929713:NIASO_RS09835
uniprot id: W0F0Y1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

929713:NIASO RS19345
gene id: 929713:NIASO_RS19345
uniprot id: W0F685
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

929713:NIASO RS00015
gene id: 929713:NIASO_RS00015
uniprot id: W0EY38
names: Similarity
messages: Belongs to the sulfatase family.

929713:NIASO RS13540
gene id: 929713:NIASO_RS13540
uniprot id: W0F3I0
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS05940
gene id: 929713:NIASO_RS05940
uniprot id: W0EVS1
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

929713:NIASO RS00090
gene id: 929713:NIASO_RS00090
uniprot id: W0EXV2
names: Similarity
messages: Belongs to the glutamine synthetase family.

929713:NIASO RS15270
gene id: 929713:NIASO_RS15270
uniprot id: W0EZZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

929713:NIASO RS00795
gene id: 929713:NIASO_RS00795
uniprot id: W0ETP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

929713:NIASO RS08890
gene id: 929713:NIASO_RS08890
uniprot id: W0EX48
names: Similarity
messages: Belongs to the peptidase M16 family.

929713:NIASO RS03770
gene id: 929713:NIASO_RS03770
uniprot id: W0EZG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS14110
gene id: 929713:NIASO_RS14110
uniprot id: W0F457
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

929713:NIASO RS02355
gene id: 929713:NIASO_RS02355
uniprot id: W0EU81
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

929713:NIASO RS14920
gene id: 929713:NIASO_RS14920
uniprot id: W0EZU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

929713:NIASO RS03575
gene id: 929713:NIASO_RS03575
uniprot id: W0EZE0
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS20475
gene id: 929713:NIASO_RS20475
uniprot id: W0EXQ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

929713:NIASO RS16955
gene id: 929713:NIASO_RS16955
uniprot id: W0F543
names: Similarity
messages: Belongs to the pirin family.

929713:NIASO RS02595
gene id: 929713:NIASO_RS02595
uniprot id: W0EUE8
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

929713:NIASO RS10005
gene id: 929713:NIASO_RS10005
uniprot id: W0F2G0
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

929713:NIASO RS11985
gene id: 929713:NIASO_RS11985
uniprot id: W0EYD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

929713:NIASO RS18800
gene id: 929713:NIASO_RS18800
uniprot id: W0F518
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

929713:NIASO RS17805
gene id: 929713:NIASO_RS17805
uniprot id: W0F4K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

929713:NIASO RS02065
gene id: 929713:NIASO_RS02065
uniprot id: W0EXQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

929713:NIASO RS04910
gene id: 929713:NIASO_RS04910
uniprot id: W0F0A2
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

929713:NIASO RS07880
gene id: 929713:NIASO_RS07880
uniprot id: W0F1J5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

929713:NIASO RS16975
gene id: 929713:NIASO_RS16975
uniprot id: W0F0R5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

929713:NIASO RS16345
gene id: 929713:NIASO_RS16345
uniprot id: W0F579
names: Similarity
messages: Belongs to the RutC family.

929713:NIASO RS10730
gene id: 929713:NIASO_RS10730
uniprot id: W0EXV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

929713:NIASO RS14035
gene id: 929713:NIASO_RS14035
uniprot id: W0F447
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS05070
gene id: 929713:NIASO_RS05070
uniprot id: W0EZ03
names: Similarity
messages: Belongs to the sulfatase family.

929713:NIASO RS02120
gene id: 929713:NIASO_RS02120
uniprot id: W0F5N1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

929713:NIASO RS02455
gene id: 929713:NIASO_RS02455
uniprot id: W0EUD1
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

929713:NIASO RS12435
gene id: 929713:NIASO_RS12435
uniprot id: W0EYN5
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS20480
gene id: 929713:NIASO_RS20480
uniprot id: W0EYR4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

929713:NIASO RS08235
gene id: 929713:NIASO_RS08235
uniprot id: W0F1P9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

929713:NIASO RS07940
gene id: 929713:NIASO_RS07940
uniprot id: W0F192
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

929713:NIASO RS04715
gene id: 929713:NIASO_RS04715
uniprot id: W0EYV4
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

929713:NIASO RS18505
gene id: 929713:NIASO_RS18505
uniprot id: W0F653
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

929713:NIASO RS04825
gene id: 929713:NIASO_RS04825
uniprot id: W0EVE8
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

929713:NIASO RS13035
gene id: 929713:NIASO_RS13035
uniprot id: W0F2D6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

929713:NIASO RS10875
gene id: 929713:NIASO_RS10875
uniprot id: W0F2W2
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

929713:NIASO RS12375
gene id: 929713:NIASO_RS12375
uniprot id: W0EYM9
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

929713:NIASO RS03975
gene id: 929713:NIASO_RS03975
uniprot id: W0EZJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

929713:NIASO RS16655
gene id: 929713:NIASO_RS16655
uniprot id: W0F4Z8
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS04415
gene id: 929713:NIASO_RS04415
uniprot id: W0F033
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS00440
gene id: 929713:NIASO_RS00440
uniprot id: W0ETD2
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS01500
gene id: 929713:NIASO_RS01500
uniprot id: W0EXG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

929713:NIASO RS07235
gene id: 929713:NIASO_RS07235
uniprot id: W0EWC2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

929713:NIASO RS18270
gene id: 929713:NIASO_RS18270
uniprot id: W0F4S8
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

929713:NIASO RS11815
gene id: 929713:NIASO_RS11815
uniprot id: W0F7D0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

929713:NIASO RS13365
gene id: 929713:NIASO_RS13365
uniprot id: W0F3F2
names: Similarity
messages: Belongs to the ArsC family.

929713:NIASO RS14695
gene id: 929713:NIASO_RS14695
uniprot id: W0F4I9
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

929713:NIASO RS17540
gene id: 929713:NIASO_RS17540
uniprot id: W0F125
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS14855
gene id: 929713:NIASO_RS14855
uniprot id: W0EZN3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

929713:NIASO RS13890
gene id: 929713:NIASO_RS13890
uniprot id: W0F422
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS18040
gene id: 929713:NIASO_RS18040
uniprot id: W0F141
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

929713:NIASO RS03700
gene id: 929713:NIASO_RS03700
uniprot id: W0EUU6
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

929713:NIASO RS18760
gene id: 929713:NIASO_RS18760
uniprot id: W0F1E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

929713:NIASO RS07795
gene id: 929713:NIASO_RS07795
uniprot id: W0F171
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

929713:NIASO RS09850
gene id: 929713:NIASO_RS09850
uniprot id: W0F2D3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

929713:NIASO RS00295
gene id: 929713:NIASO_RS00295
uniprot id: W0EWW1
names: Similarity
messages: Belongs to the peptidase S41A family.

929713:NIASO RS00820
gene id: 929713:NIASO_RS00820
uniprot id: W0ETP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

929713:NIASO RS02665
gene id: 929713:NIASO_RS02665
uniprot id: W0EXX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

929713:NIASO RS07915
gene id: 929713:NIASO_RS07915
uniprot id: W0F188
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

929713:NIASO RS06845
gene id: 929713:NIASO_RS06845
uniprot id: W0F0Q7
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS02625
gene id: 929713:NIASO_RS02625
uniprot id: W0F758
names: Similarity
messages: Belongs to the universal stress protein A family.

929713:NIASO RS10725
gene id: 929713:NIASO_RS10725
uniprot id: W0F2B3
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

929713:NIASO RS09720
gene id: 929713:NIASO_RS09720
uniprot id: W0EXC2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

929713:NIASO RS13975
gene id: 929713:NIASO_RS13975
uniprot id: W0EZ81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS16850
gene id: 929713:NIASO_RS16850
uniprot id: W0F5F2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

929713:NIASO RS07705
gene id: 929713:NIASO_RS07705
uniprot id: W0F1H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

929713:NIASO RS16740
gene id: 929713:NIASO_RS16740
uniprot id: W0F410
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS05690
gene id: 929713:NIASO_RS05690
uniprot id: W0EZ70
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

929713:NIASO RS02055
gene id: 929713:NIASO_RS02055
uniprot id: W0EZ24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

929713:NIASO RS15350
gene id: 929713:NIASO_RS15350
uniprot id: W0EZV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

929713:NIASO RS02895
gene id: 929713:NIASO_RS02895
uniprot id: W0EZD8
names: Similarity
messages: Belongs to the glutamate synthase family.

929713:NIASO RS05015
gene id: 929713:NIASO_RS05015
uniprot id: W0EVE9
names: Similarity
messages: Belongs to the threonine aldolase family.

929713:NIASO RS14610
gene id: 929713:NIASO_RS14610
uniprot id: W0F4H4
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS10690
gene id: 929713:NIASO_RS10690
uniprot id: W0F1C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

929713:NIASO RS09105
gene id: 929713:NIASO_RS09105
uniprot id: W0EX74
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS10065
gene id: 929713:NIASO_RS10065
uniprot id: W0EXI8
names: Similarity
messages: Belongs to the glycosyl hydrolase.

929713:NIASO RS10035
gene id: 929713:NIASO_RS10035
uniprot id: W0F217
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS03580
gene id: 929713:NIASO_RS03580
uniprot id: W0EUT0
names: Subcellular Location Annotation
messages: Nucleus

929713:NIASO RS14495
gene id: 929713:NIASO_RS14495
uniprot id: W0EZI6
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS09870
gene id: 929713:NIASO_RS09870
uniprot id: W0EXE9
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

929713:NIASO RS02635
gene id: 929713:NIASO_RS02635
uniprot id: W0EUF1
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

929713:NIASO RS18160
gene id: 929713:NIASO_RS18160
uniprot id: W0F4R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

929713:NIASO RS00155
gene id: 929713:NIASO_RS00155
uniprot id: W0ETE1
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

929713:NIASO RS13765
gene id: 929713:NIASO_RS13765
uniprot id: W0EZ89
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

929713:NIASO RS12665
gene id: 929713:NIASO_RS12665
uniprot id: W0F295
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

929713:NIASO RS01935
gene id: 929713:NIASO_RS01935
uniprot id: W0EU19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

929713:NIASO RS12800
gene id: 929713:NIASO_RS12800
uniprot id: W0EYU5
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

929713:NIASO RS17350
gene id: 929713:NIASO_RS17350
uniprot id: W0F5A3
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

929713:NIASO RS09745
gene id: 929713:NIASO_RS09745
uniprot id: W0F1X3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

929713:NIASO RS00675
gene id: 929713:NIASO_RS00675
uniprot id: W0EY30
names: Subcellular Location Annotation
messages: Cytoplasm

929713:NIASO RS15450
gene id: 929713:NIASO_RS15450
uniprot id: W0F4U8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

929713:NIASO RS04265
gene id: 929713:NIASO_RS04265
uniprot id: W0EV59
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

929713:NIASO RS16395
gene id: 929713:NIASO_RS16395
uniprot id: W0F0C5
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS06595
gene id: 929713:NIASO_RS06595
uniprot id: W0EZI3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS01640
gene id: 929713:NIASO_RS01640
uniprot id: W0EU18
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

929713:NIASO RS12040
gene id: 929713:NIASO_RS12040
uniprot id: W0EYD6
names: Similarity
messages: Belongs to the GARS family.

929713:NIASO RS10060
gene id: 929713:NIASO_RS10060
uniprot id: W0F222
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

929713:NIASO RS00445
gene id: 929713:NIASO_RS00445
uniprot id: W0EYA5
names: Similarity
messages: Belongs to the thioredoxin family.

929713:NIASO RS08700
gene id: 929713:NIASO_RS08700
uniprot id: W0EX20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

929713:NIASO RS15250
gene id: 929713:NIASO_RS15250
uniprot id: W0F3E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

929713:NIASO RS01925
gene id: 929713:NIASO_RS01925
uniprot id: W0EYN1
names: Subcellular Location Annotation
messages: Mitochondrion

929713:NIASO RS11250
gene id: 929713:NIASO_RS11250
uniprot id: W0F1P1
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS01085
gene id: 929713:NIASO_RS01085
uniprot id: W0ETR4
names: Similarity
messages: Belongs to the BshC family.

929713:NIASO RS05700
gene id: 929713:NIASO_RS05700
uniprot id: W0EVM7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

929713:NIASO RS03210
gene id: 929713:NIASO_RS03210
uniprot id: W0EZ93
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

929713:NIASO RS05030
gene id: 929713:NIASO_RS05030
uniprot id: W0EYZ8
names: Caution
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS13525
gene id: 929713:NIASO_RS13525
uniprot id: W0F3X2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

929713:NIASO RS09420
gene id: 929713:NIASO_RS09420
uniprot id: W0EXC8
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS09250
gene id: 929713:NIASO_RS09250
uniprot id: W0EX97
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS17610
gene id: 929713:NIASO_RS17610
uniprot id: W0F4H6
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

929713:NIASO RS15820
gene id: 929713:NIASO_RS15820
uniprot id: W0F027
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS03435
gene id: 929713:NIASO_RS03435
uniprot id: W0EZC1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

929713:NIASO RS10275
gene id: 929713:NIASO_RS10275
uniprot id: W0F255
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

929713:NIASO RS17085
gene id: 929713:NIASO_RS17085
uniprot id: W0F9D8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

929713:NIASO RS00590
gene id: 929713:NIASO_RS00590
uniprot id: W0F203
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

929713:NIASO RS15255
gene id: 929713:NIASO_RS15255
uniprot id: W0F4D2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

929713:NIASO RS17905
gene id: 929713:NIASO_RS17905
uniprot id: W0F4M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

929713:NIASO RS17765
gene id: 929713:NIASO_RS17765
uniprot id: W0F150
names: Similarity
messages: Belongs to the AHA1 family.

929713:NIASO RS01695
gene id: 929713:NIASO_RS01695
uniprot id: W0EXJ4
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

929713:NIASO RS19305
gene id: 929713:NIASO_RS19305
uniprot id: W0F1S4
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

929713:NIASO RS02855
gene id: 929713:NIASO_RS02855
uniprot id: W0EZD3
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

929713:NIASO RS13840
gene id: 929713:NIASO_RS13840
uniprot id: W0EZ62
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

929713:NIASO RS03815
gene id: 929713:NIASO_RS03815
uniprot id: W0F603
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

929713:NIASO RS15880
gene id: 929713:NIASO_RS15880
uniprot id: W0F036
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

929713:NIASO RS06575
gene id: 929713:NIASO_RS06575
uniprot id: W0F0L4
names: Similarity
messages: Belongs to the disproportionating enzyme family.

929713:NIASO RS05675
gene id: 929713:NIASO_RS05675
uniprot id: W0EVM1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

929713:NIASO RS17855
gene id: 929713:NIASO_RS17855
uniprot id: W0F887
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.
messages: Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).

929713:NIASO RS01880
gene id: 929713:NIASO_RS01880
uniprot id: W0EU09
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS02700
gene id: 929713:NIASO_RS02700
uniprot id: W0EUG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

929713:NIASO RS01490
gene id: 929713:NIASO_RS01490
uniprot id: W0EYT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

929713:NIASO RS14535
gene id: 929713:NIASO_RS14535
uniprot id: W0F4F9
names: Similarity
messages: Belongs to the sulfatase family.

929713:NIASO RS13835
gene id: 929713:NIASO_RS13835
uniprot id: W0F3M6
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

929713:NIASO RS06260
gene id: 929713:NIASO_RS06260
uniprot id: W0EVV0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS12935
gene id: 929713:NIASO_RS12935
uniprot id: W0F387
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS06450
gene id: 929713:NIASO_RS06450
uniprot id: W0EVY4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS06810
gene id: 929713:NIASO_RS06810
uniprot id: W0EW49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

929713:NIASO RS05180
gene id: 929713:NIASO_RS05180
uniprot id: W0EVI7
names: Similarity
messages: Belongs to the peptidase S41A family.

929713:NIASO RS03160
gene id: 929713:NIASO_RS03160
uniprot id: W0EZH2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

929713:NIASO RS16530
gene id: 929713:NIASO_RS16530
uniprot id: W0F0J2
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS16300
gene id: 929713:NIASO_RS16300
uniprot id: W0F0E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

929713:NIASO RS09225
gene id: 929713:NIASO_RS09225
uniprot id: W0F0Q2
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS12910
gene id: 929713:NIASO_RS12910
uniprot id: W0EYR3
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS13995
gene id: 929713:NIASO_RS13995
uniprot id: W0F2U6
names: Similarity
messages: Belongs to the ComB family.

929713:NIASO RS13135
gene id: 929713:NIASO_RS13135
uniprot id: W0EYU9
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

929713:NIASO RS03405
gene id: 929713:NIASO_RS03405
uniprot id: W0EY87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

929713:NIASO RS02310
gene id: 929713:NIASO_RS02310
uniprot id: W0EUB0
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

929713:NIASO RS10965
gene id: 929713:NIASO_RS10965
uniprot id: W0EY52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS00115
gene id: 929713:NIASO_RS00115
uniprot id: W0EWT5
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS09515
gene id: 929713:NIASO_RS09515
uniprot id: W0F289
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

929713:NIASO RS17105
gene id: 929713:NIASO_RS17105
uniprot id: W0F561
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

929713:NIASO RS11695
gene id: 929713:NIASO_RS11695
uniprot id: W0F3A0
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

929713:NIASO RS17495
gene id: 929713:NIASO_RS17495
uniprot id: W0F4F7
names: Similarity
messages: Belongs to the RecJ family.

929713:NIASO RS12135
gene id: 929713:NIASO_RS12135
uniprot id: W0F2W9
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

929713:NIASO RS17180
gene id: 929713:NIASO_RS17180
uniprot id: W0F0U0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

929713:NIASO RS03250
gene id: 929713:NIASO_RS03250
uniprot id: W0EZ98
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

929713:NIASO RS09490
gene id: 929713:NIASO_RS09490
uniprot id: W0F0T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

929713:NIASO RS13225
gene id: 929713:NIASO_RS13225
uniprot id: W0F2G5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

929713:NIASO RS11050
gene id: 929713:NIASO_RS11050
uniprot id: W0F1L0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS01610
gene id: 929713:NIASO_RS01610
uniprot id: W0EXH9
names: Similarity
messages: Belongs to the peptidase S8 family.

929713:NIASO RS08485
gene id: 929713:NIASO_RS08485
uniprot id: W0F1F5
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS09820
gene id: 929713:NIASO_RS09820
uniprot id: W0EXD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS13020
gene id: 929713:NIASO_RS13020
uniprot id: W0EYS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

929713:NIASO RS07165
gene id: 929713:NIASO_RS07165
uniprot id: W0EZR9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

929713:NIASO RS05930
gene id: 929713:NIASO_RS05930
uniprot id: W0EVR0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

929713:NIASO RS06220
gene id: 929713:NIASO_RS06220
uniprot id: W0F0G3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS12010
gene id: 929713:NIASO_RS12010
uniprot id: W0F3E4
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

929713:NIASO RS10550
gene id: 929713:NIASO_RS10550
uniprot id: W0EXW8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

929713:NIASO RS02005
gene id: 929713:NIASO_RS02005
uniprot id: W0EU74
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS16550
gene id: 929713:NIASO_RS16550
uniprot id: W0F5A9
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

929713:NIASO RS01860
gene id: 929713:NIASO_RS01860
uniprot id: W0EXL8
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS08085
gene id: 929713:NIASO_RS08085
uniprot id: W0F1B5
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

929713:NIASO RS10435
gene id: 929713:NIASO_RS10435
uniprot id: W0EXQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRP transporter (TC 2.A.7.5) family.
messages: Cell membrane
messages: Membrane

929713:NIASO RS06870
gene id: 929713:NIASO_RS06870
uniprot id: W0EW69
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS14485
gene id: 929713:NIASO_RS14485
uniprot id: W0F430
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

929713:NIASO RS19500
gene id: 929713:NIASO_RS19500
uniprot id: W0F6K4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

929713:NIASO RS09410
gene id: 929713:NIASO_RS09410
uniprot id: W0EX80
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS14560
gene id: 929713:NIASO_RS14560
uniprot id: W0F4G4
names: Similarity
messages: Belongs to the polysaccharide lyase 8 family.

929713:NIASO RS15510
gene id: 929713:NIASO_RS15510
uniprot id: W0F3J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

929713:NIASO RS14345
gene id: 929713:NIASO_RS14345
uniprot id: W0EZH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

929713:NIASO RS19275
gene id: 929713:NIASO_RS19275
uniprot id: W0F1R9
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS08050
gene id: 929713:NIASO_RS08050
uniprot id: W0F1B1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

929713:NIASO RS14445
gene id: 929713:NIASO_RS14445
uniprot id: W0EZM8
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS02575
gene id: 929713:NIASO_RS02575
uniprot id: W0EXW6
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

929713:NIASO RS05685
gene id: 929713:NIASO_RS05685
uniprot id: W0EVN7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS01810
gene id: 929713:NIASO_RS01810
uniprot id: W0EXL1
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS12805
gene id: 929713:NIASO_RS12805
uniprot id: W0F2B1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

929713:NIASO RS09230
gene id: 929713:NIASO_RS09230
uniprot id: W0F1Q0
names: Similarity
messages: Belongs to the AHA1 family.

929713:NIASO RS00885
gene id: 929713:NIASO_RS00885
uniprot id: W0EYH9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS07520
gene id: 929713:NIASO_RS07520
uniprot id: W0EWI6
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

929713:NIASO RS11725
gene id: 929713:NIASO_RS11725
uniprot id: W0F3A3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

929713:NIASO RS05755
gene id: 929713:NIASO_RS05755
uniprot id: W0F095
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

929713:NIASO RS03790
gene id: 929713:NIASO_RS03790
uniprot id: W0EYE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

929713:NIASO RS08920
gene id: 929713:NIASO_RS08920
uniprot id: W0EWZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

929713:NIASO RS10140
gene id: 929713:NIASO_RS10140
uniprot id: W0F135
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

929713:NIASO RS13025
gene id: 929713:NIASO_RS13025
uniprot id: W0F3R4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

929713:NIASO RS03705
gene id: 929713:NIASO_RS03705
uniprot id: W0EZP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

929713:NIASO RS05770
gene id: 929713:NIASO_RS05770
uniprot id: W0EVQ0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS07850
gene id: 929713:NIASO_RS07850
uniprot id: W0EWM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

929713:NIASO RS08150
gene id: 929713:NIASO_RS08150
uniprot id: W0EWU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

929713:NIASO RS13950
gene id: 929713:NIASO_RS13950
uniprot id: W0F433
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

929713:NIASO RS18960
gene id: 929713:NIASO_RS18960
uniprot id: W0F1M7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

929713:NIASO RS08860
gene id: 929713:NIASO_RS08860
uniprot id: W0F1J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

929713:NIASO RS17785
gene id: 929713:NIASO_RS17785
uniprot id: W0F110
names: Similarity
messages: Belongs to the UPF0502 family.

929713:NIASO RS07415
gene id: 929713:NIASO_RS07415
uniprot id: W0F0Z0
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

929713:NIASO RS09580
gene id: 929713:NIASO_RS09580
uniprot id: W0F1V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

929713:NIASO RS08225
gene id: 929713:NIASO_RS08225
uniprot id: W0F0A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

929713:NIASO RS16195
gene id: 929713:NIASO_RS16195
uniprot id: W0F091
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

929713:NIASO RS12855
gene id: 929713:NIASO_RS12855
uniprot id: W0F446
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

929713:NIASO RS09610
gene id: 929713:NIASO_RS09610
uniprot id: W0F1V3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

929713:NIASO RS03845
gene id: 929713:NIASO_RS03845
uniprot id: W0EUZ9
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS18210
gene id: 929713:NIASO_RS18210
uniprot id: W0F621
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

929713:NIASO RS13220
gene id: 929713:NIASO_RS13220
uniprot id: W0EZ07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

929713:NIASO RS06840
gene id: 929713:NIASO_RS06840
uniprot id: W0F305
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS16290
gene id: 929713:NIASO_RS16290
uniprot id: W0F0A1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

929713:NIASO RS06860
gene id: 929713:NIASO_RS06860
uniprot id: W0EW54
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS15610
gene id: 929713:NIASO_RS15610
uniprot id: W0F4J0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

929713:NIASO RS00060
gene id: 929713:NIASO_RS00060
uniprot id: W0EWS6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

929713:NIASO RS09840
gene id: 929713:NIASO_RS09840
uniprot id: W0F1Y7
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS00435
gene id: 929713:NIASO_RS00435
uniprot id: W0EXZ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

929713:NIASO RS07885
gene id: 929713:NIASO_RS07885
uniprot id: W0EWR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

929713:NIASO RS15175
gene id: 929713:NIASO_RS15175
uniprot id: W0F4B7
names: Similarity
messages: Belongs to the DSD1 family.

929713:NIASO RS09510
gene id: 929713:NIASO_RS09510
uniprot id: W0EX89
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

929713:NIASO RS18900
gene id: 929713:NIASO_RS18900
uniprot id: W0F6C6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

929713:NIASO RS13660
gene id: 929713:NIASO_RS13660
uniprot id: W0F3J7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

929713:NIASO RS04555
gene id: 929713:NIASO_RS04555
uniprot id: W0EZV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

929713:NIASO RS10365
gene id: 929713:NIASO_RS10365
uniprot id: W0EXP0
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS10675
gene id: 929713:NIASO_RS10675
uniprot id: W0EXU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

929713:NIASO RS07600
gene id: 929713:NIASO_RS07600
uniprot id: W0EWK7
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

929713:NIASO RS08705
gene id: 929713:NIASO_RS08705
uniprot id: W0F0G8
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

929713:NIASO RS15470
gene id: 929713:NIASO_RS15470
uniprot id: W0EZX5
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

929713:NIASO RS07830
gene id: 929713:NIASO_RS07830
uniprot id: W0F1I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

929713:NIASO RS07020
gene id: 929713:NIASO_RS07020
uniprot id: W0EW92
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS07365
gene id: 929713:NIASO_RS07365
uniprot id: W0F190
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS01035
gene id: 929713:NIASO_RS01035
uniprot id: W0ETQ6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

929713:NIASO RS13090
gene id: 929713:NIASO_RS13090
uniprot id: W0F461
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS13120
gene id: 929713:NIASO_RS13120
uniprot id: W0EYZ1
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS12065
gene id: 929713:NIASO_RS12065
uniprot id: H1NJ36
names: Similarity
messages: Belongs to the hyi family.

929713:NIASO RS00305
gene id: 929713:NIASO_RS00305
uniprot id: W0ETA6
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

929713:NIASO RS08240
gene id: 929713:NIASO_RS08240
uniprot id: W0EWV7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

929713:NIASO RS02485
gene id: 929713:NIASO_RS02485
uniprot id: W0EUD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

929713:NIASO RS01525
gene id: 929713:NIASO_RS01525
uniprot id: W0EU04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

929713:NIASO RS18165
gene id: 929713:NIASO_RS18165
uniprot id: W0F5P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

929713:NIASO RS15285
gene id: 929713:NIASO_RS15285
uniprot id: W0EZU9
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

929713:NIASO RS15265
gene id: 929713:NIASO_RS15265
uniprot id: W0F4S0
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

929713:NIASO RS09725
gene id: 929713:NIASO_RS09725
uniprot id: W0F2B5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

929713:NIASO RS17395
gene id: 929713:NIASO_RS17395
uniprot id: W0F4E3
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

929713:NIASO RS08675
gene id: 929713:NIASO_RS08675
uniprot id: W0F0G4
names: Subcellular Location Annotation
messages: Cytoplasm

929713:NIASO RS00055
gene id: 929713:NIASO_RS00055
uniprot id: W0ETC5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

929713:NIASO RS15395
gene id: 929713:NIASO_RS15395
uniprot id: W0F004
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS00870
gene id: 929713:NIASO_RS00870
uniprot id: W0EY62
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

929713:NIASO RS09555
gene id: 929713:NIASO_RS09555
uniprot id: W0F1U6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

929713:NIASO RS03740
gene id: 929713:NIASO_RS03740
uniprot id: W0EUY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

929713:NIASO RS01520
gene id: 929713:NIASO_RS01520
uniprot id: W0EYU2
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

929713:NIASO RS09070
gene id: 929713:NIASO_RS09070
uniprot id: W0EX25
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

929713:NIASO RS17970
gene id: 929713:NIASO_RS17970
uniprot id: W0F132
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

929713:NIASO RS15785
gene id: 929713:NIASO_RS15785
uniprot id: W0F3N5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

929713:NIASO RS10735
gene id: 929713:NIASO_RS10735
uniprot id: W0F2T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

929713:NIASO RS07815
gene id: 929713:NIASO_RS07815
uniprot id: W0F045
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

929713:NIASO RS08845
gene id: 929713:NIASO_RS08845
uniprot id: W0EX43
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

929713:NIASO RS02645
gene id: 929713:NIASO_RS02645
uniprot id: W0EYZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

929713:NIASO RS19190
gene id: 929713:NIASO_RS19190
uniprot id: W0F1R4
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS11110
gene id: 929713:NIASO_RS11110
uniprot id: W0F308
names: Similarity
messages: Belongs to the barstar family.

929713:NIASO RS09385
gene id: 929713:NIASO_RS09385
uniprot id: W0EX76
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS06890
gene id: 929713:NIASO_RS06890
uniprot id: W0F7J6
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS00830
gene id: 929713:NIASO_RS00830
uniprot id: W0EY54
names: Similarity
messages: Belongs to the peptidase C1 family.

929713:NIASO RS09830
gene id: 929713:NIASO_RS09830
uniprot id: W0EXJ1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS05860
gene id: 929713:NIASO_RS05860
uniprot id: W0EZA1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

929713:NIASO RS04735
gene id: 929713:NIASO_RS04735
uniprot id: W0EVD6
names: Similarity
messages: Belongs to the AHA1 family.

929713:NIASO RS12370
gene id: 929713:NIASO_RS12370
uniprot id: W0F417
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS07805
gene id: 929713:NIASO_RS07805
uniprot id: W0F1I2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

929713:NIASO RS10350
gene id: 929713:NIASO_RS10350
uniprot id: W0EXT9
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

929713:NIASO RS09575
gene id: 929713:NIASO_RS09575
uniprot id: W0F0U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

929713:NIASO RS06735
gene id: 929713:NIASO_RS06735
uniprot id: W0F0Y7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS04560
gene id: 929713:NIASO_RS04560
uniprot id: W0EVA0
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

929713:NIASO RS08030
gene id: 929713:NIASO_RS08030
uniprot id: W0F366
names: Similarity
messages: Belongs to the universal stress protein A family.

929713:NIASO RS15110
gene id: 929713:NIASO_RS15110
uniprot id: W0F4P1
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

929713:NIASO RS03120
gene id: 929713:NIASO_RS03120
uniprot id: W0EY45
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

929713:NIASO RS15160
gene id: 929713:NIASO_RS15160
uniprot id: W0F4Q1
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS19455
gene id: 929713:NIASO_RS19455
uniprot id: W0F6A5
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS16700
gene id: 929713:NIASO_RS16700
uniprot id: W0F0L8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

929713:NIASO RS09810
gene id: 929713:NIASO_RS09810
uniprot id: W0F0X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS11760
gene id: 929713:NIASO_RS11760
uniprot id: W0F1X0
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

929713:NIASO RS18355
gene id: 929713:NIASO_RS18355
uniprot id: W0F4T7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

929713:NIASO RS13625
gene id: 929713:NIASO_RS13625
uniprot id: W0F3J1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

929713:NIASO RS11800
gene id: 929713:NIASO_RS11800
uniprot id: W0EYA8
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS08275
gene id: 929713:NIASO_RS08275
uniprot id: W0F0B5
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

929713:NIASO RS13030
gene id: 929713:NIASO_RS13030
uniprot id: W0EYX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

929713:NIASO RS11875
gene id: 929713:NIASO_RS11875
uniprot id: W0EYB8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

929713:NIASO RS14925
gene id: 929713:NIASO_RS14925
uniprot id: W0F3A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

929713:NIASO RS18510
gene id: 929713:NIASO_RS18510
uniprot id: W0F1E7
names: Similarity
messages: Belongs to the threonine synthase family.

929713:NIASO RS03935
gene id: 929713:NIASO_RS03935
uniprot id: W0EV15
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS16505
gene id: 929713:NIASO_RS16505
uniprot id: W0F3X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

929713:NIASO RS08640
gene id: 929713:NIASO_RS08640
uniprot id: W0F0F9
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

929713:NIASO RS17255
gene id: 929713:NIASO_RS17255
uniprot id: W0F0R6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

929713:NIASO RS13415
gene id: 929713:NIASO_RS13415
uniprot id: W0EYZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS08010
gene id: 929713:NIASO_RS08010
uniprot id: W0EWT1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

929713:NIASO RS00700
gene id: 929713:NIASO_RS00700
uniprot id: W0EX22
names: Similarity
messages: Belongs to the OprB family.

929713:NIASO RS13575
gene id: 929713:NIASO_RS13575
uniprot id: W0F2M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS19335
gene id: 929713:NIASO_RS19335
uniprot id: W0F1S9
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

929713:NIASO RS04615
gene id: 929713:NIASO_RS04615
uniprot id: W0F069
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS19325
gene id: 929713:NIASO_RS19325
uniprot id: W0F6I2
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

929713:NIASO RS02000
gene id: 929713:NIASO_RS02000
uniprot id: W0EZ15
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS16480
gene id: 929713:NIASO_RS16480
uniprot id: W0F4X7
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

929713:NIASO RS12485
gene id: 929713:NIASO_RS12485
uniprot id: W0F3L7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

929713:NIASO RS14605
gene id: 929713:NIASO_RS14605
uniprot id: W0EZK5
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.
messages: Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man-Glc) to mannose 1-phosphate (Man1P) and glucose.

929713:NIASO RS07035
gene id: 929713:NIASO_RS07035
uniprot id: W0EW83
names: Similarity
messages: Belongs to the serpin family.

929713:NIASO RS08970
gene id: 929713:NIASO_RS08970
uniprot id: W0EX11
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

929713:NIASO RS10610
gene id: 929713:NIASO_RS10610
uniprot id: W0F1B0
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

929713:NIASO RS00640
gene id: 929713:NIASO_RS00640
uniprot id: W0EY24
names: Function
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

929713:NIASO RS16010
gene id: 929713:NIASO_RS16010
uniprot id: W0F0A6
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

929713:NIASO RS16745
gene id: 929713:NIASO_RS16745
uniprot id: W0F508
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

929713:NIASO RS04790
gene id: 929713:NIASO_RS04790
uniprot id: W0F087
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

929713:NIASO RS17365
gene id: 929713:NIASO_RS17365
uniprot id: W0F0Z9
names: Similarity
messages: Belongs to the UxaA family.

929713:NIASO RS19030
gene id: 929713:NIASO_RS19030
uniprot id: W0F643
names: Similarity
messages: Belongs to the MQO family.

929713:NIASO RS09285
gene id: 929713:NIASO_RS09285
uniprot id: W0F0R3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

929713:NIASO RS12255
gene id: 929713:NIASO_RS12255
uniprot id: W0EYG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

929713:NIASO RS18580
gene id: 929713:NIASO_RS18580
uniprot id: W0F1B2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

929713:NIASO RS12325
gene id: 929713:NIASO_RS12325
uniprot id: W0F2Z4
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

929713:NIASO RS16885
gene id: 929713:NIASO_RS16885
uniprot id: W0F0Q0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS03380
gene id: 929713:NIASO_RS03380
uniprot id: W0EZB3
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

929713:NIASO RS06025
gene id: 929713:NIASO_RS06025
uniprot id: W0EZC4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

929713:NIASO RS11850
gene id: 929713:NIASO_RS11850
uniprot id: W0F3C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

929713:NIASO RS17500
gene id: 929713:NIASO_RS17500
uniprot id: W0F5E9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

929713:NIASO RS16620
gene id: 929713:NIASO_RS16620
uniprot id: W0F4Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

929713:NIASO RS17120
gene id: 929713:NIASO_RS17120
uniprot id: W0F0T3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

929713:NIASO RS15830
gene id: 929713:NIASO_RS15830
uniprot id: W0F078
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

929713:NIASO RS05110
gene id: 929713:NIASO_RS05110
uniprot id: W0F013
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

929713:NIASO RS04155
gene id: 929713:NIASO_RS04155
uniprot id: W0EZM3
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS06245
gene id: 929713:NIASO_RS06245
uniprot id: W0EZE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

929713:NIASO RS14970
gene id: 929713:NIASO_RS14970
uniprot id: W0F495
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

929713:NIASO RS17025
gene id: 929713:NIASO_RS17025
uniprot id: W0F0S6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS17590
gene id: 929713:NIASO_RS17590
uniprot id: W0F0Y8
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS06540
gene id: 929713:NIASO_RS06540
uniprot id: W0EZI0
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

929713:NIASO RS02670
gene id: 929713:NIASO_RS02670
uniprot id: W0EZ00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

929713:NIASO RS13145
gene id: 929713:NIASO_RS13145
uniprot id: W0EYZ7
names: Subunit
messages: Homodimer.

929713:NIASO RS19140
gene id: 929713:NIASO_RS19140
uniprot id: W0F1Q8
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

929713:NIASO RS05785
gene id: 929713:NIASO_RS05785
uniprot id: W0EVP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

929713:NIASO RS04050
gene id: 929713:NIASO_RS04050
uniprot id: W0EV35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

929713:NIASO RS02080
gene id: 929713:NIASO_RS02080
uniprot id: W0EZ27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

929713:NIASO RS06865
gene id: 929713:NIASO_RS06865
uniprot id: W0F109
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS08745
gene id: 929713:NIASO_RS08745
uniprot id: W0F1I3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

929713:NIASO RS00165
gene id: 929713:NIASO_RS00165
uniprot id: W0EWU0
names: Similarity
messages: Belongs to the bleomycin resistance protein family.

929713:NIASO RS16870
gene id: 929713:NIASO_RS16870
uniprot id: W0F0K1
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS13075
gene id: 929713:NIASO_RS13075
uniprot id: W0F3S3
names: Similarity
messages: Belongs to the DinB family.

929713:NIASO RS15050
gene id: 929713:NIASO_RS15050
uniprot id: W0EZQ9
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

929713:NIASO RS15105
gene id: 929713:NIASO_RS15105
uniprot id: W0EZR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

929713:NIASO RS12795
gene id: 929713:NIASO_RS12795
uniprot id: W0F3P8
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

929713:NIASO RS17345
gene id: 929713:NIASO_RS17345
uniprot id: W0F4B9
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

929713:NIASO RS00145
gene id: 929713:NIASO_RS00145
uniprot id: W0ET78
names: Similarity
messages: Belongs to the arginase family.

929713:NIASO RS18415
gene id: 929713:NIASO_RS18415
uniprot id: W0F189
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

929713:NIASO RS10560
gene id: 929713:NIASO_RS10560
uniprot id: W0F198
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS13485
gene id: 929713:NIASO_RS13485
uniprot id: W0F3W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

929713:NIASO RS16540
gene id: 929713:NIASO_RS16540
uniprot id: W0F4Y4
names: Similarity
messages: Belongs to the LacAB/RpiB family.

929713:NIASO RS04365
gene id: 929713:NIASO_RS04365
uniprot id: W0F024
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

929713:NIASO RS05235
gene id: 929713:NIASO_RS05235
uniprot id: W0F026
names: Similarity
messages: Belongs to the Nudix hydrolase family.

929713:NIASO RS09460
gene id: 929713:NIASO_RS09460
uniprot id: W0F1T6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS04445
gene id: 929713:NIASO_RS04445
uniprot id: W0F038
names: Similarity
messages: Belongs to the AIR synthase family.

929713:NIASO RS17005
gene id: 929713:NIASO_RS17005
uniprot id: W0F460
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS02685
gene id: 929713:NIASO_RS02685
uniprot id: W0EZA7
names: Similarity
messages: Belongs to the peptidase C1 family.

929713:NIASO RS01030
gene id: 929713:NIASO_RS01030
uniprot id: W0EYB0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

929713:NIASO RS14120
gene id: 929713:NIASO_RS14120
uniprot id: W0F464
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS11380
gene id: 929713:NIASO_RS11380
uniprot id: W0F347
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

929713:NIASO RS04020
gene id: 929713:NIASO_RS04020
uniprot id: W0EZV3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

929713:NIASO RS09345
gene id: 929713:NIASO_RS09345
uniprot id: W0EXB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

929713:NIASO RS14285
gene id: 929713:NIASO_RS14285
uniprot id: W0F4C3
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

929713:NIASO RS07990
gene id: 929713:NIASO_RS07990
uniprot id: W0F1A1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

929713:NIASO RS02590
gene id: 929713:NIASO_RS02590
uniprot id: W0EZ95
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

929713:NIASO RS02535
gene id: 929713:NIASO_RS02535
uniprot id: W0EUA6
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

929713:NIASO RS06850
gene id: 929713:NIASO_RS06850
uniprot id: W0F7V2
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS19485
gene id: 929713:NIASO_RS19485
uniprot id: W0F1Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

929713:NIASO RS11370
gene id: 929713:NIASO_RS11370
uniprot id: W0F2M1
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

929713:NIASO RS01395
gene id: 929713:NIASO_RS01395
uniprot id: W0EYG5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

929713:NIASO RS08760
gene id: 929713:NIASO_RS08760
uniprot id: W0F1X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

929713:NIASO RS11140
gene id: 929713:NIASO_RS11140
uniprot id: W0F313
names: Similarity
messages: Belongs to the ParB family.

929713:NIASO RS06330
gene id: 929713:NIASO_RS06330
uniprot id: W0EVW1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-55 and Arg-58) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

929713:NIASO RS04625
gene id: 929713:NIASO_RS04625
uniprot id: W0EYV0
names: Function
names: Subunit
messages: Homodimer.
messages: Represses transcription of the icaADBC operon necessary for biofilm production.

929713:NIASO RS16940
gene id: 929713:NIASO_RS16940
uniprot id: W0F5G7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

929713:NIASO RS05910
gene id: 929713:NIASO_RS05910
uniprot id: W0EZA6
names: Similarity
messages: Belongs to the GroES chaperonin family.

929713:NIASO RS15645
gene id: 929713:NIASO_RS15645
uniprot id: W0F4Y5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

929713:NIASO RS07680
gene id: 929713:NIASO_RS07680
uniprot id: W0EWN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

929713:NIASO RS06375
gene id: 929713:NIASO_RS06375
uniprot id: W0EVY1
names: Similarity
messages: Belongs to the peptidase S9A family.

929713:NIASO RS01080
gene id: 929713:NIASO_RS01080
uniprot id: W0EYC1
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

929713:NIASO RS16775
gene id: 929713:NIASO_RS16775
uniprot id: W0F513
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS06685
gene id: 929713:NIASO_RS06685
uniprot id: W0EZJ5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS15195
gene id: 929713:NIASO_RS15195
uniprot id: W0EZY0
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS13060
gene id: 929713:NIASO_RS13060
uniprot id: W0F2E1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

929713:NIASO RS12900
gene id: 929713:NIASO_RS12900
uniprot id: W0F451
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS06895
gene id: 929713:NIASO_RS06895
uniprot id: W0F310
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS11175
gene id: 929713:NIASO_RS11175
uniprot id: W0EY81
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

929713:NIASO RS12045
gene id: 929713:NIASO_RS12045
uniprot id: W0F3F0
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS18025
gene id: 929713:NIASO_RS18025
uniprot id: W0F187
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS03840
gene id: 929713:NIASO_RS03840
uniprot id: W0EZS1
names: Similarity
messages: Belongs to the DapA family.

929713:NIASO RS05295
gene id: 929713:NIASO_RS05295
uniprot id: W0F698
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS03820
gene id: 929713:NIASO_RS03820
uniprot id: W0EUZ4
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

929713:NIASO RS02025
gene id: 929713:NIASO_RS02025
uniprot id: W0EZ19
names: Similarity
messages: Belongs to the DapA family.

929713:NIASO RS00935
gene id: 929713:NIASO_RS00935
uniprot id: W0EY83
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

929713:NIASO RS16400
gene id: 929713:NIASO_RS16400
uniprot id: W0F590
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

929713:NIASO RS04375
gene id: 929713:NIASO_RS04375
uniprot id: W0EYR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

929713:NIASO RS12395
gene id: 929713:NIASO_RS12395
uniprot id: W0EYJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

929713:NIASO RS10310
gene id: 929713:NIASO_RS10310
uniprot id: W0F2K8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

929713:NIASO RS14545
gene id: 929713:NIASO_RS14545
uniprot id: W0F349
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS16580
gene id: 929713:NIASO_RS16580
uniprot id: W0F3Y1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

929713:NIASO RS11575
gene id: 929713:NIASO_RS11575
uniprot id: W0EYC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

929713:NIASO RS16865
gene id: 929713:NIASO_RS16865
uniprot id: W0F530
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS12740
gene id: 929713:NIASO_RS12740
uniprot id: W0EYP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS17810
gene id: 929713:NIASO_RS17810
uniprot id: W0F5J5
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS11975
gene id: 929713:NIASO_RS11975
uniprot id: W0F201
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

929713:NIASO RS07205
gene id: 929713:NIASO_RS07205
uniprot id: W0EWB7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

929713:NIASO RS05040
gene id: 929713:NIASO_RS05040
uniprot id: W0EVF3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

929713:NIASO RS19150
gene id: 929713:NIASO_RS19150
uniprot id: W0F8F9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

929713:NIASO RS05485
gene id: 929713:NIASO_RS05485
uniprot id: W0F0H2
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS07240
gene id: 929713:NIASO_RS07240
uniprot id: W0F169
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

929713:NIASO RS09825
gene id: 929713:NIASO_RS09825
uniprot id: W0F2C8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

929713:NIASO RS15605
gene id: 929713:NIASO_RS15605
uniprot id: W0F3K7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

929713:NIASO RS07700
gene id: 929713:NIASO_RS07700
uniprot id: W0EWK3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

929713:NIASO RS12585
gene id: 929713:NIASO_RS12585
uniprot id: W0EYR1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

929713:NIASO RS06640
gene id: 929713:NIASO_RS06640
uniprot id: W0EW14
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

929713:NIASO RS07615
gene id: 929713:NIASO_RS07615
uniprot id: W0F003
names: Similarity
messages: Belongs to the polysaccharide lyase 8 family.

929713:NIASO RS14185
gene id: 929713:NIASO_RS14185
uniprot id: W0EZF6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

929713:NIASO RS15025
gene id: 929713:NIASO_RS15025
uniprot id: W0F4A3
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS18795
gene id: 929713:NIASO_RS18795
uniprot id: W0F1J8
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

929713:NIASO RS05165
gene id: 929713:NIASO_RS05165
uniprot id: W0F021
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS02875
gene id: 929713:NIASO_RS02875
uniprot id: W0EZ37
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

929713:NIASO RS16755
gene id: 929713:NIASO_RS16755
uniprot id: W0F5D5
names: Similarity
messages: Belongs to the Skp family.

929713:NIASO RS00760
gene id: 929713:NIASO_RS00760
uniprot id: W0ETN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

929713:NIASO RS15015
gene id: 929713:NIASO_RS15015
uniprot id: W0EZV7
names: Similarity
messages: Belongs to the sulfatase family.

929713:NIASO RS07865
gene id: 929713:NIASO_RS07865
uniprot id: W0F055
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

929713:NIASO RS00620
gene id: 929713:NIASO_RS00620
uniprot id: W0ETG0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS12275
gene id: 929713:NIASO_RS12275
uniprot id: W0F3I1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

929713:NIASO RS11420
gene id: 929713:NIASO_RS11420
uniprot id: W0EYA7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

929713:NIASO RS13930
gene id: 929713:NIASO_RS13930
uniprot id: W0EZB6
names: Similarity
messages: Belongs to the arginase family.

929713:NIASO RS18500
gene id: 929713:NIASO_RS18500
uniprot id: W0F199
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

929713:NIASO RS10315
gene id: 929713:NIASO_RS10315
uniprot id: W0EXT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

929713:NIASO RS00545
gene id: 929713:NIASO_RS00545
uniprot id: W0EYC0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

929713:NIASO RS09270
gene id: 929713:NIASO_RS09270
uniprot id: W0EX60
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

929713:NIASO RS09035
gene id: 929713:NIASO_RS09035
uniprot id: W0F1M0
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

929713:NIASO RS16515
gene id: 929713:NIASO_RS16515
uniprot id: W0F0E4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

929713:NIASO RS13070
gene id: 929713:NIASO_RS13070
uniprot id: W0EYT8
names: Similarity
messages: Belongs to the beta-eliminating lyase family.

929713:NIASO RS05665
gene id: 929713:NIASO_RS05665
uniprot id: W0EZ65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

929713:NIASO RS18595
gene id: 929713:NIASO_RS18595
uniprot id: W0F4X9
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS13050
gene id: 929713:NIASO_RS13050
uniprot id: W0F3R8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

929713:NIASO RS07710
gene id: 929713:NIASO_RS07710
uniprot id: W0EWN8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

929713:NIASO RS01970
gene id: 929713:NIASO_RS01970
uniprot id: W0EZ10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

929713:NIASO RS15855
gene id: 929713:NIASO_RS15855
uniprot id: W0F032
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

929713:NIASO RS12100
gene id: 929713:NIASO_RS12100
uniprot id: W0F2W5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

929713:NIASO RS03965
gene id: 929713:NIASO_RS03965
uniprot id: W0EV20
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS17145
gene id: 929713:NIASO_RS17145
uniprot id: W0F0T7
names: Similarity
messages: Belongs to the ClpA/ClpB family.

929713:NIASO RS10410
gene id: 929713:NIASO_RS10410
uniprot id: W0F179
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

929713:NIASO RS10425
gene id: 929713:NIASO_RS10425
uniprot id: W0F276
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

929713:NIASO RS13650
gene id: 929713:NIASO_RS13650
uniprot id: W0EZ71
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

929713:NIASO RS17545
gene id: 929713:NIASO_RS17545
uniprot id: W0F4G7
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS07825
gene id: 929713:NIASO_RS07825
uniprot id: W0EWL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

929713:NIASO RS17850
gene id: 929713:NIASO_RS17850
uniprot id: W0F5X6
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

929713:NIASO RS04440
gene id: 929713:NIASO_RS04440
uniprot id: W0EV84
names: Similarity
messages: Belongs to the ribF family.

929713:NIASO RS18280
gene id: 929713:NIASO_RS18280
uniprot id: W0F5Q4
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS17265
gene id: 929713:NIASO_RS17265
uniprot id: W0F0V5
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS00860
gene id: 929713:NIASO_RS00860
uniprot id: W0EX50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

929713:NIASO RS09275
gene id: 929713:NIASO_RS09275
uniprot id: W0F258
names: Similarity
messages: Belongs to the glycosyl hydrolase 63 family.

929713:NIASO RS01665
gene id: 929713:NIASO_RS01665
uniprot id: W0EU20
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS14000
gene id: 929713:NIASO_RS14000
uniprot id: W0F3Q1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

929713:NIASO RS17875
gene id: 929713:NIASO_RS17875
uniprot id: W0F4L6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS05935
gene id: 929713:NIASO_RS05935
uniprot id: W0F0N5
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

929713:NIASO RS00005
gene id: 929713:NIASO_RS00005
uniprot id: W0ET57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

929713:NIASO RS03960
gene id: 929713:NIASO_RS03960
uniprot id: W0EZU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

929713:NIASO RS12655
gene id: 929713:NIASO_RS12655
uniprot id: W0F3N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

929713:NIASO RS11905
gene id: 929713:NIASO_RS11905
uniprot id: W0F1Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

929713:NIASO RS10650
gene id: 929713:NIASO_RS10650
uniprot id: W0EXT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

929713:NIASO RS04575
gene id: 929713:NIASO_RS04575
uniprot id: W0EYU3
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

929713:NIASO RS17530
gene id: 929713:NIASO_RS17530
uniprot id: W0F0Y2
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

929713:NIASO RS06015
gene id: 929713:NIASO_RS06015
uniprot id: W0F0P6
names: Similarity
messages: Belongs to the Lgt family.

929713:NIASO RS18695
gene id: 929713:NIASO_RS18695
uniprot id: W0F1H7
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

929713:NIASO RS01865
gene id: 929713:NIASO_RS01865
uniprot id: W0F234
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

929713:NIASO RS12350
gene id: 929713:NIASO_RS12350
uniprot id: W0F253
names: Similarity
messages: Belongs to the SCO1/2 family.

929713:NIASO RS04270
gene id: 929713:NIASO_RS04270
uniprot id: W0F010
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

929713:NIASO RS11070
gene id: 929713:NIASO_RS11070
uniprot id: W0EY19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

929713:NIASO RS18915
gene id: 929713:NIASO_RS18915
uniprot id: W0F619
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS18715
gene id: 929713:NIASO_RS18715
uniprot id: W0F692
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

929713:NIASO RS07430
gene id: 929713:NIASO_RS07430
uniprot id: W0F1A2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

929713:NIASO RS08915
gene id: 929713:NIASO_RS08915
uniprot id: W0F1K3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

929713:NIASO RS06585
gene id: 929713:NIASO_RS06585
uniprot id: W0F0W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

929713:NIASO RS11560
gene id: 929713:NIASO_RS11560
uniprot id: W0F2P6
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

929713:NIASO RS12700
gene id: 929713:NIASO_RS12700
uniprot id: W0F357
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

929713:NIASO RS11390
gene id: 929713:NIASO_RS11390
uniprot id: W0F1R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

929713:NIASO RS05600
gene id: 929713:NIASO_RS05600
uniprot id: W0F070
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

929713:NIASO RS11500
gene id: 929713:NIASO_RS11500
uniprot id: W0F2N9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

929713:NIASO RS01270
gene id: 929713:NIASO_RS01270
uniprot id: W0EYE8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

929713:NIASO RS11160
gene id: 929713:NIASO_RS11160
uniprot id: W0EY32
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

929713:NIASO RS04030
gene id: 929713:NIASO_RS04030
uniprot id: W0EYI9
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

929713:NIASO RS18300
gene id: 929713:NIASO_RS18300
uniprot id: W0F4T3
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS13170
gene id: 929713:NIASO_RS13170
uniprot id: W0EYV5
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

929713:NIASO RS17270
gene id: 929713:NIASO_RS17270
uniprot id: W0F4A2
names: Similarity
messages: Belongs to the AHA1 family.

929713:NIASO RS09755
gene id: 929713:NIASO_RS09755
uniprot id: W0F2B9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

929713:NIASO RS02660
gene id: 929713:NIASO_RS02660
uniprot id: W0EUF5
names: Similarity
messages: Belongs to the NusB family.

929713:NIASO RS17275
gene id: 929713:NIASO_RS17275
uniprot id: W0F587
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

929713:NIASO RS00095
gene id: 929713:NIASO_RS00095
uniprot id: W0ET73
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

929713:NIASO RS05960
gene id: 929713:NIASO_RS05960
uniprot id: W0F0P0
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

929713:NIASO RS06430
gene id: 929713:NIASO_RS06430
uniprot id: W0EVZ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

929713:NIASO RS18190
gene id: 929713:NIASO_RS18190
uniprot id: W0F4R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

929713:NIASO RS10665
gene id: 929713:NIASO_RS10665
uniprot id: W0F1C1
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS06470
gene id: 929713:NIASO_RS06470
uniprot id: W0F0K3
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS06475
gene id: 929713:NIASO_RS06475
uniprot id: W0EVZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

929713:NIASO RS10510
gene id: 929713:NIASO_RS10510
uniprot id: W0F2N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

929713:NIASO RS14990
gene id: 929713:NIASO_RS14990
uniprot id: W0F3B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm

929713:NIASO RS13235
gene id: 929713:NIASO_RS13235
uniprot id: W0EYW5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

929713:NIASO RS12820
gene id: 929713:NIASO_RS12820
uniprot id: W0F371
names: Similarity
messages: Belongs to the peptidase C1 family.

929713:NIASO RS07835
gene id: 929713:NIASO_RS07835
uniprot id: W0EWQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

929713:NIASO RS07510
gene id: 929713:NIASO_RS07510
uniprot id: W0EWH2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

929713:NIASO RS13490
gene id: 929713:NIASO_RS13490
uniprot id: W0EZ49
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

929713:NIASO RS04315
gene id: 929713:NIASO_RS04315
uniprot id: W0EV89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

929713:NIASO RS10715
gene id: 929713:NIASO_RS10715
uniprot id: W0EXZ6
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

929713:NIASO RS11670
gene id: 929713:NIASO_RS11670
uniprot id: W0F395
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

929713:NIASO RS09675
gene id: 929713:NIASO_RS09675
uniprot id: W0F0V7
names: Similarity
messages: Belongs to the AHA1 family.

929713:NIASO RS11045
gene id: 929713:NIASO_RS11045
uniprot id: W0EY64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

929713:NIASO RS05890
gene id: 929713:NIASO_RS05890
uniprot id: W0F0N0
names: Similarity
messages: Belongs to the UPF0162 family.

929713:NIASO RS11650
gene id: 929713:NIASO_RS11650
uniprot id: W0EYE2
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

929713:NIASO RS05680
gene id: 929713:NIASO_RS05680
uniprot id: W0F0J7
names: Similarity
messages: Belongs to the UPF0234 family.

929713:NIASO RS08210
gene id: 929713:NIASO_RS08210
uniprot id: W0F1P3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

929713:NIASO RS01355
gene id: 929713:NIASO_RS01355
uniprot id: W0EYF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

929713:NIASO RS18790
gene id: 929713:NIASO_RS18790
uniprot id: W0F6A6
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS15485
gene id: 929713:NIASO_RS15485
uniprot id: W0F3I4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

929713:NIASO RS10915
gene id: 929713:NIASO_RS10915
uniprot id: W0F895
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS13180
gene id: 929713:NIASO_RS13180
uniprot id: W0EZ02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

929713:NIASO RS15445
gene id: 929713:NIASO_RS15445
uniprot id: W0EZX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

929713:NIASO RS00195
gene id: 929713:NIASO_RS00195
uniprot id: W0EWU4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

929713:NIASO RS02530
gene id: 929713:NIASO_RS02530
uniprot id: W0EYX8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS08550
gene id: 929713:NIASO_RS08550
uniprot id: W0F1U4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

929713:NIASO RS06120
gene id: 929713:NIASO_RS06120
uniprot id: W0EVT7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

929713:NIASO RS08965
gene id: 929713:NIASO_RS08965
uniprot id: W0F1L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

929713:NIASO RS00490
gene id: 929713:NIASO_RS00490
uniprot id: W0EY07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L-fucose isomerase family.
messages: Converts the aldose L-fucose into the corresponding ketose L-fuculose.
messages: Cytoplasm

929713:NIASO RS17310
gene id: 929713:NIASO_RS17310
uniprot id: W0F4A6
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS04740
gene id: 929713:NIASO_RS04740
uniprot id: W0EYV9
names: Similarity
messages: Belongs to the DEAD box helicase family.

929713:NIASO RS08490
gene id: 929713:NIASO_RS08490
uniprot id: W0EWU3
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS16375
gene id: 929713:NIASO_RS16375
uniprot id: W0F584
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS09595
gene id: 929713:NIASO_RS09595
uniprot id: W0F3G7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS13850
gene id: 929713:NIASO_RS13850
uniprot id: W0F7P9
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS14265
gene id: 929713:NIASO_RS14265
uniprot id: W0EZK0
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS11485
gene id: 929713:NIASO_RS11485
uniprot id: W0EYB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

929713:NIASO RS10210
gene id: 929713:NIASO_RS10210
uniprot id: W0F2J8
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

929713:NIASO RS06620
gene id: 929713:NIASO_RS06620
uniprot id: W0F0X0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

929713:NIASO RS16790
gene id: 929713:NIASO_RS16790
uniprot id: W0F0N3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

929713:NIASO RS17840
gene id: 929713:NIASO_RS17840
uniprot id: W0F5J8
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

929713:NIASO RS11715
gene id: 929713:NIASO_RS11715
uniprot id: W0EY96
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

929713:NIASO RS02650
gene id: 929713:NIASO_RS02650
uniprot id: W0EUC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

929713:NIASO RS16325
gene id: 929713:NIASO_RS16325
uniprot id: W0F0F5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

929713:NIASO RS05775
gene id: 929713:NIASO_RS05775
uniprot id: W0EZ85
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

929713:NIASO RS03835
gene id: 929713:NIASO_RS03835
uniprot id: W0EUW9
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS02330
gene id: 929713:NIASO_RS02330
uniprot id: W0EZ58
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

929713:NIASO RS11265
gene id: 929713:NIASO_RS11265
uniprot id: W0F332
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

929713:NIASO RS12840
gene id: 929713:NIASO_RS12840
uniprot id: W0EYV2
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS11440
gene id: 929713:NIASO_RS11440
uniprot id: W0F8L6
names: Similarity
messages: Belongs to the SusD family.

929713:NIASO RS10150
gene id: 929713:NIASO_RS10150
uniprot id: W0EXK4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

929713:NIASO RS00605
gene id: 929713:NIASO_RS00605
uniprot id: W0ETL4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS07810
gene id: 929713:NIASO_RS07810
uniprot id: W0EWQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

929713:NIASO RS05965
gene id: 929713:NIASO_RS05965
uniprot id: W0EVS4
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

929713:NIASO RS07225
gene id: 929713:NIASO_RS07225
uniprot id: W0F0W3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

929713:NIASO RS13670
gene id: 929713:NIASO_RS13670
uniprot id: W0F3Z1
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

929713:NIASO RS12545
gene id: 929713:NIASO_RS12545
uniprot id: W0F3M4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

929713:NIASO RS19000
gene id: 929713:NIASO_RS19000
uniprot id: W0F547
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

929713:NIASO RS05275
gene id: 929713:NIASO_RS05275
uniprot id: W0F0F3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

929713:NIASO RS01365
gene id: 929713:NIASO_RS01365
uniprot id: W0F5I9
names: Subcellular Location Annotation
messages: Membrane

929713:NIASO RS12520
gene id: 929713:NIASO_RS12520
uniprot id: W0EYQ2
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.