914150:TQ33 RS08190
gene id: 914150:TQ33_RS08190
uniprot id: A0A0F6RCN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

914150:TQ33 RS01760
gene id: 914150:TQ33_RS01760
uniprot id: A0A0F6TPV6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

914150:TQ33 RS02205
gene id: 914150:TQ33_RS02205
uniprot id: A0A0F6TP71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

914150:TQ33 RS07640
gene id: 914150:TQ33_RS07640
uniprot id: A0A0F6TRS5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

914150:TQ33 RS02780
gene id: 914150:TQ33_RS02780
uniprot id: A0A0F6RBX4
names: Similarity
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

914150:TQ33 RS03685
gene id: 914150:TQ33_RS03685
uniprot id: A0A0F6RC44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

914150:TQ33 RS07905
gene id: 914150:TQ33_RS07905
uniprot id: A0A0F6RCL3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

914150:TQ33 RS00795
gene id: 914150:TQ33_RS00795
uniprot id: A0A0F6RBH5
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

914150:TQ33 RS01935
gene id: 914150:TQ33_RS01935
uniprot id: A0A0F6RBS0
names: Similarity
messages: Belongs to the SAICAR synthetase family.

914150:TQ33 RS04055
gene id: 914150:TQ33_RS04055
uniprot id: A0A0F6TPY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

914150:TQ33 RS04470
gene id: 914150:TQ33_RS04470
uniprot id: A0A0F6TQF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

914150:TQ33 RS09190
gene id: 914150:TQ33_RS09190
uniprot id: A0A0F6TRZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

914150:TQ33 RS05560
gene id: 914150:TQ33_RS05560
uniprot id: A0A0F6RCH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

914150:TQ33 RS05745
gene id: 914150:TQ33_RS05745
uniprot id: A0A0F6TQY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

914150:TQ33 RS08700
gene id: 914150:TQ33_RS08700
uniprot id: A0A0F6RD73
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

914150:TQ33 RS08570
gene id: 914150:TQ33_RS08570
uniprot id: A0A0F6TS32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

914150:TQ33 RS07560
gene id: 914150:TQ33_RS07560
uniprot id: A0A0F6TRH4
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS06965
gene id: 914150:TQ33_RS06965
uniprot id: A0A0F6TQV2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

914150:TQ33 RS06320
gene id: 914150:TQ33_RS06320
uniprot id: A0A0F6TQT3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

914150:TQ33 RS05840
gene id: 914150:TQ33_RS05840
uniprot id: A0A0F6TQY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

914150:TQ33 RS03385
gene id: 914150:TQ33_RS03385
uniprot id: A0A0F6RBL0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

914150:TQ33 RS00800
gene id: 914150:TQ33_RS00800
uniprot id: A0A0F6TPC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

914150:TQ33 RS08455
gene id: 914150:TQ33_RS08455
uniprot id: A0A0F6TR87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Membrane

914150:TQ33 RS10300
gene id: 914150:TQ33_RS10300
uniprot id: A0A0F6TRV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

914150:TQ33 RS01390
gene id: 914150:TQ33_RS01390
uniprot id: A0A0F6TPI9
names: Similarity
messages: Belongs to the peptidase S41A family.

914150:TQ33 RS00810
gene id: 914150:TQ33_RS00810
uniprot id: A0A0F6TNU0
names: Similarity
messages: Belongs to the YicC/YloC family.

914150:TQ33 RS00435
gene id: 914150:TQ33_RS00435
uniprot id: A0A0F6TNT8
names: Similarity
messages: Belongs to the peptidase S8 family.

914150:TQ33 RS07970
gene id: 914150:TQ33_RS07970
uniprot id: A0A0F6TRW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

914150:TQ33 RS11530
gene id: 914150:TQ33_RS11530
uniprot id: A0A0F6TSZ9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS07685
gene id: 914150:TQ33_RS07685
uniprot id: A0A0F6RCJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

914150:TQ33 RS03965
gene id: 914150:TQ33_RS03965
uniprot id: A0A0F6TPR4
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

914150:TQ33 RS09880
gene id: 914150:TQ33_RS09880
uniprot id: A0A0F6RDG5
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

914150:TQ33 RS03930
gene id: 914150:TQ33_RS03930
uniprot id: A0A0F6TPX5
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Methylates ribosomal protein uL3 on a specific glutamine residue.

914150:TQ33 RS10345
gene id: 914150:TQ33_RS10345
uniprot id: A0A0F6TRW1
names: Similarity
messages: Belongs to the PhoH family.

914150:TQ33 RS09415
gene id: 914150:TQ33_RS09415
uniprot id: A0A0F6RDD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

914150:TQ33 RS03530
gene id: 914150:TQ33_RS03530
uniprot id: A0A0F6RC32
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

914150:TQ33 RS02995
gene id: 914150:TQ33_RS02995
uniprot id: A0A0F6RBI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

914150:TQ33 RS03810
gene id: 914150:TQ33_RS03810
uniprot id: A0A0F6TQ91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

914150:TQ33 RS10415
gene id: 914150:TQ33_RS10415
uniprot id: A0A0F6TSQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

914150:TQ33 RS03270
gene id: 914150:TQ33_RS03270
uniprot id: A0A0F6TPQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

914150:TQ33 RS10995
gene id: 914150:TQ33_RS10995
uniprot id: A0A0F6TS57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Sulfur carrier protein which probably makes part of a sulfur-relay system.

914150:TQ33 RS10275
gene id: 914150:TQ33_RS10275
uniprot id: A0A0F6TS43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

914150:TQ33 RS01885
gene id: 914150:TQ33_RS01885
uniprot id: A0A0F6TPW8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

914150:TQ33 RS01870
gene id: 914150:TQ33_RS01870
uniprot id: A0A0F6TPA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

914150:TQ33 RS11415
gene id: 914150:TQ33_RS11415
uniprot id: A0A0F6TSN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

914150:TQ33 RS03520
gene id: 914150:TQ33_RS03520
uniprot id: A0A0F6TPK7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

914150:TQ33 RS02290
gene id: 914150:TQ33_RS02290
uniprot id: A0A0F6TP79
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

914150:TQ33 RS09820
gene id: 914150:TQ33_RS09820
uniprot id: A0A0F6TRR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

914150:TQ33 RS01300
gene id: 914150:TQ33_RS01300
uniprot id: A0A0F6RBL6
names: Similarity
messages: Belongs to the HSP15 family.

914150:TQ33 RS03365
gene id: 914150:TQ33_RS03365
uniprot id: A0A0F6TPT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

914150:TQ33 RS07545
gene id: 914150:TQ33_RS07545
uniprot id: A0A0F6RCY3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

914150:TQ33 RS11495
gene id: 914150:TQ33_RS11495
uniprot id: A0A0F6RDD1
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

914150:TQ33 RS05630
gene id: 914150:TQ33_RS05630
uniprot id: A0A0F6TQH1
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

914150:TQ33 RS10635
gene id: 914150:TQ33_RS10635
uniprot id: A0A0F6TSF6
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

914150:TQ33 RS08800
gene id: 914150:TQ33_RS08800
uniprot id: A0A0F6RD82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

914150:TQ33 RS00060
gene id: 914150:TQ33_RS00060
uniprot id: A0A0F6RBB5
names: Similarity
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

914150:TQ33 RS02930
gene id: 914150:TQ33_RS02930
uniprot id: A0A0F6RBH7
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

914150:TQ33 RS00815
gene id: 914150:TQ33_RS00815
uniprot id: A0A0F6TNZ7
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

914150:TQ33 RS01240
gene id: 914150:TQ33_RS01240
uniprot id: A0A0F6TP43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

914150:TQ33 RS07370
gene id: 914150:TQ33_RS07370
uniprot id: A0A0F6RCH4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

914150:TQ33 RS04160
gene id: 914150:TQ33_RS04160
uniprot id: A0A0F6TQC5
names: Similarity
messages: Belongs to the citrate synthase family.

914150:TQ33 RS07110
gene id: 914150:TQ33_RS07110
uniprot id: A0A0F6TQW4
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS05205
gene id: 914150:TQ33_RS05205
uniprot id: A0A0F6TQC7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

914150:TQ33 RS06805
gene id: 914150:TQ33_RS06805
uniprot id: A0A0F6TQY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

914150:TQ33 RS10910
gene id: 914150:TQ33_RS10910
uniprot id: A0A0F6TS15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

914150:TQ33 RS02345
gene id: 914150:TQ33_RS02345
uniprot id: A0A0F6RBU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

914150:TQ33 RS00445
gene id: 914150:TQ33_RS00445
uniprot id: A0A0F6TNV3
names: Similarity
messages: Belongs to the peptidase S8 family.

914150:TQ33 RS00750
gene id: 914150:TQ33_RS00750
uniprot id: A0A0F6TPI6
names: Caution
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS10120
gene id: 914150:TQ33_RS10120
uniprot id: A0A0F6TSB9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

914150:TQ33 RS06915
gene id: 914150:TQ33_RS06915
uniprot id: A0A0F6TQR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

914150:TQ33 RS10260
gene id: 914150:TQ33_RS10260
uniprot id: A0A0F6TRV1
names: Similarity
messages: Belongs to the UPF0250 family.

914150:TQ33 RS03650
gene id: 914150:TQ33_RS03650
uniprot id: A0A0F6TPU5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

914150:TQ33 RS09515
gene id: 914150:TQ33_RS09515
uniprot id: A0A0F6TRN4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

914150:TQ33 RS10035
gene id: 914150:TQ33_RS10035
uniprot id: A0A0F6TSB2
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

914150:TQ33 RS04040
gene id: 914150:TQ33_RS04040
uniprot id: A0A0F6TQB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

914150:TQ33 RS02270
gene id: 914150:TQ33_RS02270
uniprot id: A0A0F6TQ10
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS02510
gene id: 914150:TQ33_RS02510
uniprot id: A0A0F6RBE6
names: Similarity
messages: Belongs to the asparagine synthetase family.

914150:TQ33 RS02935
gene id: 914150:TQ33_RS02935
uniprot id: A0A0F6TQ11
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

914150:TQ33 RS00450
gene id: 914150:TQ33_RS00450
uniprot id: A0A0F6RAY4
names: Similarity
messages: Belongs to the peptidase S8 family.

914150:TQ33 RS02075
gene id: 914150:TQ33_RS02075
uniprot id: A0A0F6RBB2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

914150:TQ33 RS00005
gene id: 914150:TQ33_RS00005
uniprot id: A0A0F6RBB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

914150:TQ33 RS02910
gene id: 914150:TQ33_RS02910
uniprot id: A0A0F6TPL8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

914150:TQ33 RS08410
gene id: 914150:TQ33_RS08410
uniprot id: A0A0F6RD49
names: Similarity
messages: Belongs to the peptidase M13 family.

914150:TQ33 RS04140
gene id: 914150:TQ33_RS04140
uniprot id: A0A0F6RBR1
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

914150:TQ33 RS06285
gene id: 914150:TQ33_RS06285
uniprot id: A0A0F6TRE2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

914150:TQ33 RS07620
gene id: 914150:TQ33_RS07620
uniprot id: A0A0F6TR18
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

914150:TQ33 RS07035
gene id: 914150:TQ33_RS07035
uniprot id: A0A0F6RCV1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

914150:TQ33 RS02265
gene id: 914150:TQ33_RS02265
uniprot id: A0A0F6RBT4
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

914150:TQ33 RS07520
gene id: 914150:TQ33_RS07520
uniprot id: A0A0F6TQX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

914150:TQ33 RS09785
gene id: 914150:TQ33_RS09785
uniprot id: A0A0F6TSK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

914150:TQ33 RS01825
gene id: 914150:TQ33_RS01825
uniprot id: A0A0F6TPA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

914150:TQ33 RS06230
gene id: 914150:TQ33_RS06230
uniprot id: A0A0F6TQM4
names: Similarity
messages: Belongs to the P(II) protein family.

914150:TQ33 RS10885
gene id: 914150:TQ33_RS10885
uniprot id: A0A0F6TSA9
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS09375
gene id: 914150:TQ33_RS09375
uniprot id: A0A0F6RCW9
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

914150:TQ33 RS08135
gene id: 914150:TQ33_RS08135
uniprot id: A0A0F6RCN0
names: Similarity
messages: Belongs to the ArsC family.

914150:TQ33 RS10815
gene id: 914150:TQ33_RS10815
uniprot id: A0A0F6RDL6
names: Similarity
messages: Belongs to the GSP E family.

914150:TQ33 RS06895
gene id: 914150:TQ33_RS06895
uniprot id: A0A0F6RCU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

914150:TQ33 RS06300
gene id: 914150:TQ33_RS06300
uniprot id: A0A0F6RC84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribosome modulation factor family.
messages: Cytoplasm
messages: During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).

914150:TQ33 RS03390
gene id: 914150:TQ33_RS03390
uniprot id: A0A0F6TPJ2
names: Similarity
messages: Belongs to the SlyX family.

914150:TQ33 RS03225
gene id: 914150:TQ33_RS03225
uniprot id: A0A0F6TPQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

914150:TQ33 RS02080
gene id: 914150:TQ33_RS02080
uniprot id: A0A0F6TP61
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

914150:TQ33 RS05060
gene id: 914150:TQ33_RS05060
uniprot id: A0A0F6TQ81
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

914150:TQ33 RS08745
gene id: 914150:TQ33_RS08745
uniprot id: A0A0F6TS54
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS09015
gene id: 914150:TQ33_RS09015
uniprot id: A0A0F6TS88
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS11160
gene id: 914150:TQ33_RS11160
uniprot id: A0A0F6TS40
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

914150:TQ33 RS03680
gene id: 914150:TQ33_RS03680
uniprot id: A0A0F6TQ78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

914150:TQ33 RS01895
gene id: 914150:TQ33_RS01895
uniprot id: A0A0F6TPP7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

914150:TQ33 RS00215
gene id: 914150:TQ33_RS00215
uniprot id: A0A0F6RBC7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

914150:TQ33 RS02365
gene id: 914150:TQ33_RS02365
uniprot id: A0A0F6TPU9
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

914150:TQ33 RS05765
gene id: 914150:TQ33_RS05765
uniprot id: A0A0F6RCJ6
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

914150:TQ33 RS08175
gene id: 914150:TQ33_RS08175
uniprot id: A0A0F6TRE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

914150:TQ33 RS10500
gene id: 914150:TQ33_RS10500
uniprot id: A0A0F6TSR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

914150:TQ33 RS06990
gene id: 914150:TQ33_RS06990
uniprot id: A0A0F6TRK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

914150:TQ33 RS08835
gene id: 914150:TQ33_RS08835
uniprot id: A0A0F6TS65
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

914150:TQ33 RS02055
gene id: 914150:TQ33_RS02055
uniprot id: A0A0F6TPD5
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

914150:TQ33 RS07770
gene id: 914150:TQ33_RS07770
uniprot id: A0A0F6TRJ5
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

914150:TQ33 RS04870
gene id: 914150:TQ33_RS04870
uniprot id: A0A0F6TQX8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS07610
gene id: 914150:TQ33_RS07610
uniprot id: A0A0F6RCJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

914150:TQ33 RS10760
gene id: 914150:TQ33_RS10760
uniprot id: A0A0F6RDL2
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

914150:TQ33 RS00065
gene id: 914150:TQ33_RS00065
uniprot id: A0A0F6TNR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

914150:TQ33 RS07185
gene id: 914150:TQ33_RS07185
uniprot id: A0A0F6TQX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

914150:TQ33 RS10295
gene id: 914150:TQ33_RS10295
uniprot id: A0A0F6RDI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

914150:TQ33 RS10535
gene id: 914150:TQ33_RS10535
uniprot id: A0A0F6TS73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

914150:TQ33 RS09705
gene id: 914150:TQ33_RS09705
uniprot id: A0A0F6TRZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

914150:TQ33 RS02125
gene id: 914150:TQ33_RS02125
uniprot id: A0A0F6RBB6
names: Similarity
messages: Belongs to the aspartokinase family.

914150:TQ33 RS00540
gene id: 914150:TQ33_RS00540
uniprot id: A0A0F6RBF4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

914150:TQ33 RS10405
gene id: 914150:TQ33_RS10405
uniprot id: A0A0F6TS58
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

914150:TQ33 RS06745
gene id: 914150:TQ33_RS06745
uniprot id: A0A0F6TQP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

914150:TQ33 RS08690
gene id: 914150:TQ33_RS08690
uniprot id: A0A0F6TRE3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

914150:TQ33 RS01490
gene id: 914150:TQ33_RS01490
uniprot id: A0A0F6TP68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

914150:TQ33 RS04670
gene id: 914150:TQ33_RS04670
uniprot id: A0A0F6TQ80
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

914150:TQ33 RS01145
gene id: 914150:TQ33_RS01145
uniprot id: A0A0F6TPG3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS10000
gene id: 914150:TQ33_RS10000
uniprot id: A0A0F6RD21
names: Similarity
messages: Belongs to the UPF0145 family.

914150:TQ33 RS08500
gene id: 914150:TQ33_RS08500
uniprot id: A0A0F6TR93
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

914150:TQ33 RS05355
gene id: 914150:TQ33_RS05355
uniprot id: A0A0F6RCG3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

914150:TQ33 RS11345
gene id: 914150:TQ33_RS11345
uniprot id: A0A0F6RDC0
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

914150:TQ33 RS05865
gene id: 914150:TQ33_RS05865
uniprot id: A0A0F6TQN7
names: Function
messages: Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury MerR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site.

914150:TQ33 RS01835
gene id: 914150:TQ33_RS01835
uniprot id: A0A0F6TPB8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

914150:TQ33 RS04150
gene id: 914150:TQ33_RS04150
uniprot id: A0A0F6TQL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

914150:TQ33 RS01600
gene id: 914150:TQ33_RS01600
uniprot id: A0A0F6RBP0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

914150:TQ33 RS07515
gene id: 914150:TQ33_RS07515
uniprot id: A0A0F6RCY2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

914150:TQ33 RS00220
gene id: 914150:TQ33_RS00220
uniprot id: A0A0F6TNJ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

914150:TQ33 RS08550
gene id: 914150:TQ33_RS08550
uniprot id: A0A0F6RCR1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

914150:TQ33 RS03515
gene id: 914150:TQ33_RS03515
uniprot id: A0A0F6RBL9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

914150:TQ33 RS08695
gene id: 914150:TQ33_RS08695
uniprot id: A0A0F6TRK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

914150:TQ33 RS11370
gene id: 914150:TQ33_RS11370
uniprot id: A0A0F6RDC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

914150:TQ33 RS10920
gene id: 914150:TQ33_RS10920
uniprot id: A0A0F6RDM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

914150:TQ33 RS09150
gene id: 914150:TQ33_RS09150
uniprot id: A0A0F6TRY6
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

914150:TQ33 RS01225
gene id: 914150:TQ33_RS01225
uniprot id: A0A0F6RBK9
names: Similarity
messages: Belongs to the SCO1/2 family.

914150:TQ33 RS02385
gene id: 914150:TQ33_RS02385
uniprot id: A0A0F6TPF7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

914150:TQ33 RS04695
gene id: 914150:TQ33_RS04695
uniprot id: A0A0F6TQ09
names: Similarity
messages: Belongs to the 2-oxoadipate dioxygenase/decarboxylase family.

914150:TQ33 RS04025
gene id: 914150:TQ33_RS04025
uniprot id: A0A0F6TQ12
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

914150:TQ33 RS04525
gene id: 914150:TQ33_RS04525
uniprot id: A0A0F6TPY8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS05775
gene id: 914150:TQ33_RS05775
uniprot id: A0A0F6RC47
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Transforms N(2)-succinylglutamate into succinate and glutamate.

914150:TQ33 RS00545
gene id: 914150:TQ33_RS00545
uniprot id: A0A0F6TP93
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

914150:TQ33 RS01730
gene id: 914150:TQ33_RS01730
uniprot id: A0A0F6RBQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

914150:TQ33 RS01755
gene id: 914150:TQ33_RS01755
uniprot id: A0A0F6RBQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane
messages: Membrane

914150:TQ33 RS08480
gene id: 914150:TQ33_RS08480
uniprot id: A0A0F6TS23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

914150:TQ33 RS06015
gene id: 914150:TQ33_RS06015
uniprot id: A0A0F6RC65
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

914150:TQ33 RS03330
gene id: 914150:TQ33_RS03330
uniprot id: A0A0F6TQB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

914150:TQ33 RS02085
gene id: 914150:TQ33_RS02085
uniprot id: A0A0F6TPC7
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS08580
gene id: 914150:TQ33_RS08580
uniprot id: A0A0F6TRS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

914150:TQ33 RS09235
gene id: 914150:TQ33_RS09235
uniprot id: A0A0F6TSE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

914150:TQ33 RS00250
gene id: 914150:TQ33_RS00250
uniprot id: A0A0F6RAX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

914150:TQ33 RS04965
gene id: 914150:TQ33_RS04965
uniprot id: A0A0F6TQQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

914150:TQ33 RS07525
gene id: 914150:TQ33_RS07525
uniprot id: A0A0F6RCI5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

914150:TQ33 RS10160
gene id: 914150:TQ33_RS10160
uniprot id: A0A0F6TSC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

914150:TQ33 RS10745
gene id: 914150:TQ33_RS10745
uniprot id: A0A0F6TS96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

914150:TQ33 RS06565
gene id: 914150:TQ33_RS06565
uniprot id: A0A0F6TR62
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MetJ family.
messages: Cytoplasm
messages: Homodimer.

914150:TQ33 RS05965
gene id: 914150:TQ33_RS05965
uniprot id: A0A0F6TR01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.

914150:TQ33 RS01625
gene id: 914150:TQ33_RS01625
uniprot id: A0A0F6RBP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

914150:TQ33 RS06405
gene id: 914150:TQ33_RS06405
uniprot id: A0A0F6TQP2
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

914150:TQ33 RS00255
gene id: 914150:TQ33_RS00255
uniprot id: A0A0F6TP18
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

914150:TQ33 RS10845
gene id: 914150:TQ33_RS10845
uniprot id: A0A0F6TST8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

914150:TQ33 RS09045
gene id: 914150:TQ33_RS09045
uniprot id: A0A0F6RDA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

914150:TQ33 RS06290
gene id: 914150:TQ33_RS06290
uniprot id: A0A0F6RCN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

914150:TQ33 RS09550
gene id: 914150:TQ33_RS09550
uniprot id: A0A0F6TS66
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

914150:TQ33 RS02605
gene id: 914150:TQ33_RS02605
uniprot id: A0A0F6RBV9
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

914150:TQ33 RS04485
gene id: 914150:TQ33_RS04485
uniprot id: A0A0F6TPY2
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

914150:TQ33 RS05350
gene id: 914150:TQ33_RS05350
uniprot id: A0A0F6TR37
names: Similarity
messages: Belongs to the peptidase S8 family.

914150:TQ33 RS02170
gene id: 914150:TQ33_RS02170
uniprot id: A0A0F6TPD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

914150:TQ33 RS02380
gene id: 914150:TQ33_RS02380
uniprot id: A0A0F6RBD6
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

914150:TQ33 RS10820
gene id: 914150:TQ33_RS10820
uniprot id: A0A0F6TS07
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

914150:TQ33 RS04575
gene id: 914150:TQ33_RS04575
uniprot id: A0A0F6TQ46
names: Similarity
messages: Belongs to the peptidase M16 family.

914150:TQ33 RS01025
gene id: 914150:TQ33_RS01025
uniprot id: A0A0F6TP20
names: Similarity
messages: Belongs to the CFA/CMAS family.

914150:TQ33 RS04540
gene id: 914150:TQ33_RS04540
uniprot id: A0A0F6RBV6
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

914150:TQ33 RS08005
gene id: 914150:TQ33_RS08005
uniprot id: A0A0F6TRC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

914150:TQ33 RS08515
gene id: 914150:TQ33_RS08515
uniprot id: A0A0F6RD58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

914150:TQ33 RS07985
gene id: 914150:TQ33_RS07985
uniprot id: A0A0F6RCL8
names: Similarity
messages: Belongs to the skp family.

914150:TQ33 RS04990
gene id: 914150:TQ33_RS04990
uniprot id: A0A0F6TQE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

914150:TQ33 RS09725
gene id: 914150:TQ33_RS09725
uniprot id: A0A0F6RDF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

914150:TQ33 RS11385
gene id: 914150:TQ33_RS11385
uniprot id: A0A0F6RDQ7
names: Similarity
messages: Belongs to the DprA/Smf family.

914150:TQ33 RS10220
gene id: 914150:TQ33_RS10220
uniprot id: A0A0F6TRY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

914150:TQ33 RS11425
gene id: 914150:TQ33_RS11425
uniprot id: A0A0F6TS71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family.
messages: Periplasm

914150:TQ33 RS04060
gene id: 914150:TQ33_RS04060
uniprot id: A0A0F6RC72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

914150:TQ33 RS04790
gene id: 914150:TQ33_RS04790
uniprot id: A0A0F6RBX3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

914150:TQ33 RS06620
gene id: 914150:TQ33_RS06620
uniprot id: A0A0F6RCA3
names: Similarity
messages: Belongs to the PhoH family.

914150:TQ33 RS08180
gene id: 914150:TQ33_RS08180
uniprot id: A0A0F6RD30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

914150:TQ33 RS06535
gene id: 914150:TQ33_RS06535
uniprot id: A0A0F6RCQ5
names: Cofactor
names: Function
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.

914150:TQ33 RS09460
gene id: 914150:TQ33_RS09460
uniprot id: A0A0F6TS56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

914150:TQ33 RS01650
gene id: 914150:TQ33_RS01650
uniprot id: A0A0F6TP17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

914150:TQ33 RS11540
gene id: 914150:TQ33_RS11540
uniprot id: A0A0F6RDD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

914150:TQ33 RS03295
gene id: 914150:TQ33_RS03295
uniprot id: A0A0F6TQ41
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

914150:TQ33 RS02200
gene id: 914150:TQ33_RS02200
uniprot id: A0A0F6RBC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

914150:TQ33 RS03980
gene id: 914150:TQ33_RS03980
uniprot id: A0A0F6TQ07
names: Similarity
messages: Belongs to the DEAD box helicase family.

914150:TQ33 RS02835
gene id: 914150:TQ33_RS02835
uniprot id: A0A0F6RBH1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

914150:TQ33 RS08465
gene id: 914150:TQ33_RS08465
uniprot id: A0A0F6TRB8
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

914150:TQ33 RS09615
gene id: 914150:TQ33_RS09615
uniprot id: A0A0F6TRY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

914150:TQ33 RS07900
gene id: 914150:TQ33_RS07900
uniprot id: A0A0F6TR19
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

914150:TQ33 RS01980
gene id: 914150:TQ33_RS01980
uniprot id: A0A0F6TPX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

914150:TQ33 RS08125
gene id: 914150:TQ33_RS08125
uniprot id: A0A0F6RD26
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

914150:TQ33 RS04595
gene id: 914150:TQ33_RS04595
uniprot id: A0A0F6TQR4
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

914150:TQ33 RS04720
gene id: 914150:TQ33_RS04720
uniprot id: A0A0F6TQT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

914150:TQ33 RS09185
gene id: 914150:TQ33_RS09185
uniprot id: A0A0F6TSA8
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

914150:TQ33 RS09170
gene id: 914150:TQ33_RS09170
uniprot id: A0A0F6RDB1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

914150:TQ33 RS08195
gene id: 914150:TQ33_RS08195
uniprot id: A0A0F6TRN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

914150:TQ33 RS00980
gene id: 914150:TQ33_RS00980
uniprot id: A0A0F6RB24
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS09805
gene id: 914150:TQ33_RS09805
uniprot id: A0A0F6RDG2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

914150:TQ33 RS06945
gene id: 914150:TQ33_RS06945
uniprot id: A0A0F6RCU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

914150:TQ33 RS07280
gene id: 914150:TQ33_RS07280
uniprot id: A0A0F6TR40
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

914150:TQ33 RS03360
gene id: 914150:TQ33_RS03360
uniprot id: A0A0F6RBK7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

914150:TQ33 RS05580
gene id: 914150:TQ33_RS05580
uniprot id: A0A0F6TQC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

914150:TQ33 RS03805
gene id: 914150:TQ33_RS03805
uniprot id: A0A0F6TQG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

914150:TQ33 RS01910
gene id: 914150:TQ33_RS01910
uniprot id: A0A0F6RBR9
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

914150:TQ33 RS09315
gene id: 914150:TQ33_RS09315
uniprot id: A0A0F6RCW4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

914150:TQ33 RS01170
gene id: 914150:TQ33_RS01170
uniprot id: A0A0F6TP54
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS03285
gene id: 914150:TQ33_RS03285
uniprot id: A0A0F6RBK2
names: Similarity
messages: Belongs to the GSP E family.

914150:TQ33 RS04740
gene id: 914150:TQ33_RS04740
uniprot id: A0A0F6RBX1
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

914150:TQ33 RS00715
gene id: 914150:TQ33_RS00715
uniprot id: A0A0F6TPC0
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

914150:TQ33 RS02775
gene id: 914150:TQ33_RS02775
uniprot id: A0A0F6TPL3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

914150:TQ33 RS08120
gene id: 914150:TQ33_RS08120
uniprot id: A0A0F6TR79
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

914150:TQ33 RS02660
gene id: 914150:TQ33_RS02660
uniprot id: A0A0F6TQ53
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

914150:TQ33 RS09630
gene id: 914150:TQ33_RS09630
uniprot id: A0A0F6TSI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

914150:TQ33 RS06035
gene id: 914150:TQ33_RS06035
uniprot id: A0A0F6TQQ4
names: Similarity
messages: Belongs to the AlaDH/PNT family.

914150:TQ33 RS01840
gene id: 914150:TQ33_RS01840
uniprot id: A0A0F6RB94
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

914150:TQ33 RS05385
gene id: 914150:TQ33_RS05385
uniprot id: A0A0F6TQJ1
names: Similarity
messages: Belongs to the pirin family.

914150:TQ33 RS04950
gene id: 914150:TQ33_RS04950
uniprot id: A0A0F6TQE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

914150:TQ33 RS10340
gene id: 914150:TQ33_RS10340
uniprot id: A0A0F6TSD2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

914150:TQ33 RS00175
gene id: 914150:TQ33_RS00175
uniprot id: A0A0F6RAW4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

914150:TQ33 RS11450
gene id: 914150:TQ33_RS11450
uniprot id: A0A0F6TSZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

914150:TQ33 RS04330
gene id: 914150:TQ33_RS04330
uniprot id: A0A0F6TQE1
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS03870
gene id: 914150:TQ33_RS03870
uniprot id: A0A0F6TQ96
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

914150:TQ33 RS01120
gene id: 914150:TQ33_RS01120
uniprot id: A0A0F6TP49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

914150:TQ33 RS01100
gene id: 914150:TQ33_RS01100
uniprot id: A0A0F6RBJ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

914150:TQ33 RS01785
gene id: 914150:TQ33_RS01785
uniprot id: A0A0F6TP95
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

914150:TQ33 RS10450
gene id: 914150:TQ33_RS10450
uniprot id: A0A0F6TS63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

914150:TQ33 RS10085
gene id: 914150:TQ33_RS10085
uniprot id: A0A0F6TRT4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS09715
gene id: 914150:TQ33_RS09715
uniprot id: A0A0F6TSJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

914150:TQ33 RS07995
gene id: 914150:TQ33_RS07995
uniprot id: A0A0F6TR65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

914150:TQ33 RS06220
gene id: 914150:TQ33_RS06220
uniprot id: A0A0F6TQJ4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

914150:TQ33 RS07675
gene id: 914150:TQ33_RS07675
uniprot id: A0A0F6RCY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

914150:TQ33 RS02375
gene id: 914150:TQ33_RS02375
uniprot id: A0A0F6TP86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

914150:TQ33 RS03590
gene id: 914150:TQ33_RS03590
uniprot id: A0A0F6RBM5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

914150:TQ33 RS04050
gene id: 914150:TQ33_RS04050
uniprot id: A0A0F6TPS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

914150:TQ33 RS07375
gene id: 914150:TQ33_RS07375
uniprot id: A0A0F6TRP7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS05005
gene id: 914150:TQ33_RS05005
uniprot id: A0A0F6TQQ7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

914150:TQ33 RS11685
gene id: 914150:TQ33_RS11685
uniprot id: A0A0F6RCS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZapG family.
messages: Cell inner membrane
messages: Membrane

914150:TQ33 RS01890
gene id: 914150:TQ33_RS01890
uniprot id: A0A0F6RB99
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

914150:TQ33 RS08345
gene id: 914150:TQ33_RS08345
uniprot id: A0A0F6TRG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

914150:TQ33 RS09695
gene id: 914150:TQ33_RS09695
uniprot id: A0A0F6TRS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

914150:TQ33 RS01125
gene id: 914150:TQ33_RS01125
uniprot id: A0A0F6RBK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

914150:TQ33 RS01675
gene id: 914150:TQ33_RS01675
uniprot id: A0A0F6TPU6
names: Similarity
messages: Belongs to the peptidase S8 family.

914150:TQ33 RS00960
gene id: 914150:TQ33_RS00960
uniprot id: A0A0F6TPL1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

914150:TQ33 RS01595
gene id: 914150:TQ33_RS01595
uniprot id: A0A0F6TPL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

914150:TQ33 RS00785
gene id: 914150:TQ33_RS00785
uniprot id: A0A0F6TP14
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS05960
gene id: 914150:TQ33_RS05960
uniprot id: A0A0F6RC61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

914150:TQ33 RS07845
gene id: 914150:TQ33_RS07845
uniprot id: A0A0F6RD03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

914150:TQ33 RS05240
gene id: 914150:TQ33_RS05240
uniprot id: A0A0F6TQ95
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

914150:TQ33 RS11255
gene id: 914150:TQ33_RS11255
uniprot id: A0A0F6TS85
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS04850
gene id: 914150:TQ33_RS04850
uniprot id: A0A0F6TQ73
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

914150:TQ33 RS09005
gene id: 914150:TQ33_RS09005
uniprot id: A0A0F6RCT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

914150:TQ33 RS05550
gene id: 914150:TQ33_RS05550
uniprot id: A0A0F6TQG1
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

914150:TQ33 RS10740
gene id: 914150:TQ33_RS10740
uniprot id: A0A0F6RD76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

914150:TQ33 RS08880
gene id: 914150:TQ33_RS08880
uniprot id: A0A0F6RD88
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

914150:TQ33 RS08530
gene id: 914150:TQ33_RS08530
uniprot id: A0A0F6TS28
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

914150:TQ33 RS00740
gene id: 914150:TQ33_RS00740
uniprot id: A0A0F6TP12
names: Subcellular Location Annotation
messages: Cell inner membrane

914150:TQ33 RS05805
gene id: 914150:TQ33_RS05805
uniprot id: A0A0F6TQI9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

914150:TQ33 RS05810
gene id: 914150:TQ33_RS05810
uniprot id: A0A0F6TQN2
names: Similarity
messages: Belongs to the OsmC/Ohr family.

914150:TQ33 RS11165
gene id: 914150:TQ33_RS11165
uniprot id: A0A0F6TS75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

914150:TQ33 RS06465
gene id: 914150:TQ33_RS06465
uniprot id: A0A0F6RC91
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

914150:TQ33 RS01275
gene id: 914150:TQ33_RS01275
uniprot id: A0A0F6RBL4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

914150:TQ33 RS08575
gene id: 914150:TQ33_RS08575
uniprot id: A0A0F6RCR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

914150:TQ33 RS10975
gene id: 914150:TQ33_RS10975
uniprot id: A0A0F6RD93
names: Similarity
messages: Belongs to the DEAD box helicase family.

914150:TQ33 RS03140
gene id: 914150:TQ33_RS03140
uniprot id: A0A0F6TPP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

914150:TQ33 RS01220
gene id: 914150:TQ33_RS01220
uniprot id: A0A0F6TPH0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

914150:TQ33 RS00620
gene id: 914150:TQ33_RS00620
uniprot id: A0A0F6RBG0
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

914150:TQ33 RS06665
gene id: 914150:TQ33_RS06665
uniprot id: A0A0F6RCR6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

914150:TQ33 RS02915
gene id: 914150:TQ33_RS02915
uniprot id: A0A0F6TPM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

914150:TQ33 RS08680
gene id: 914150:TQ33_RS08680
uniprot id: A0A0F6TRB3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

914150:TQ33 RS04650
gene id: 914150:TQ33_RS04650
uniprot id: A0A0F6TQ03
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

914150:TQ33 RS03595
gene id: 914150:TQ33_RS03595
uniprot id: A0A0F6TQ71
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

914150:TQ33 RS08210
gene id: 914150:TQ33_RS08210
uniprot id: A0A0F6TR89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

914150:TQ33 RS08090
gene id: 914150:TQ33_RS08090
uniprot id: A0A0F6TRD6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

914150:TQ33 RS10525
gene id: 914150:TQ33_RS10525
uniprot id: A0A0F6TS08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

914150:TQ33 RS04800
gene id: 914150:TQ33_RS04800
uniprot id: A0A0F6TQ19
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

914150:TQ33 RS09815
gene id: 914150:TQ33_RS09815
uniprot id: A0A0F6RD12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

914150:TQ33 RS09100
gene id: 914150:TQ33_RS09100
uniprot id: A0A0F6TS98
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

914150:TQ33 RS11460
gene id: 914150:TQ33_RS11460
uniprot id: A0A0F6RDR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

914150:TQ33 RS04545
gene id: 914150:TQ33_RS04545
uniprot id: A0A0F6TQ64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

914150:TQ33 RS10105
gene id: 914150:TQ33_RS10105
uniprot id: A0A0F6TS26
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

914150:TQ33 RS01135
gene id: 914150:TQ33_RS01135
uniprot id: A0A0F6RB35
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

914150:TQ33 RS03060
gene id: 914150:TQ33_RS03060
uniprot id: A0A0F6TPP4
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

914150:TQ33 RS06940
gene id: 914150:TQ33_RS06940
uniprot id: A0A0F6TRK6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

914150:TQ33 RS06075
gene id: 914150:TQ33_RS06075
uniprot id: A0A0F6RC69
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS04655
gene id: 914150:TQ33_RS04655
uniprot id: A0A0F6RCC1
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

914150:TQ33 RS10790
gene id: 914150:TQ33_RS10790
uniprot id: A0A0F6RDL4
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

914150:TQ33 RS06625
gene id: 914150:TQ33_RS06625
uniprot id: A0A0F6TQR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

914150:TQ33 RS10060
gene id: 914150:TQ33_RS10060
uniprot id: A0A0F6TS21
names: Similarity
messages: Belongs to the UPF0234 family.

914150:TQ33 RS08765
gene id: 914150:TQ33_RS08765
uniprot id: A0A0F6TRC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

914150:TQ33 RS07030
gene id: 914150:TQ33_RS07030
uniprot id: A0A0F6TR10
names: Similarity
messages: Belongs to the phosphohexose mutase family.

914150:TQ33 RS04735
gene id: 914150:TQ33_RS04735
uniprot id: A0A0F6TQ13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

914150:TQ33 RS11675
gene id: 914150:TQ33_RS11675
uniprot id: A0A0F6RCN9
names: Similarity
messages: Belongs to the peptidase S8 family.

914150:TQ33 RS01190
gene id: 914150:TQ33_RS01190
uniprot id: A0A0F6TNX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. KdkA/RfaP family.
messages: Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position.
messages: Cell inner membrane
messages: Membrane

914150:TQ33 RS04435
gene id: 914150:TQ33_RS04435
uniprot id: A0A0F6TQ33
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

914150:TQ33 RS09650
gene id: 914150:TQ33_RS09650
uniprot id: A0A0F6RDF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

914150:TQ33 RS03455
gene id: 914150:TQ33_RS03455
uniprot id: A0A0F6RC25
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

914150:TQ33 RS07835
gene id: 914150:TQ33_RS07835
uniprot id: A0A0F6TRA6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

914150:TQ33 RS07175
gene id: 914150:TQ33_RS07175
uniprot id: A0A0F6TQU0
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS06120
gene id: 914150:TQ33_RS06120
uniprot id: A0A0F6TQL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

914150:TQ33 RS00930
gene id: 914150:TQ33_RS00930
uniprot id: A0A0F6RB20
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

914150:TQ33 RS10590
gene id: 914150:TQ33_RS10590
uniprot id: A0A0F6RD65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

914150:TQ33 RS01960
gene id: 914150:TQ33_RS01960
uniprot id: A0A0F6RBS1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

914150:TQ33 RS00415
gene id: 914150:TQ33_RS00415
uniprot id: A0A0F6RBE3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

914150:TQ33 RS08510
gene id: 914150:TQ33_RS08510
uniprot id: A0A0F6TRC4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

914150:TQ33 RS08650
gene id: 914150:TQ33_RS08650
uniprot id: A0A0F6RD68
names: Similarity
messages: Belongs to the UPF0102 family.

914150:TQ33 RS09980
gene id: 914150:TQ33_RS09980
uniprot id: A0A0F6TSL2
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS02975
gene id: 914150:TQ33_RS02975
uniprot id: A0A0F6TPN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

914150:TQ33 RS11455
gene id: 914150:TQ33_RS11455
uniprot id: A0A0F6TSN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

914150:TQ33 RS06115
gene id: 914150:TQ33_RS06115
uniprot id: A0A0F6RCM5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS06175
gene id: 914150:TQ33_RS06175
uniprot id: A0A0F6RC75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

914150:TQ33 RS07980
gene id: 914150:TQ33_RS07980
uniprot id: A0A0F6TRL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

914150:TQ33 RS04660
gene id: 914150:TQ33_RS04660
uniprot id: A0A0F6TQ54
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

914150:TQ33 RS08750
gene id: 914150:TQ33_RS08750
uniprot id: A0A0F6RD77
names: Similarity
messages: Belongs to the BolA/IbaG family.

914150:TQ33 RS04065
gene id: 914150:TQ33_RS04065
uniprot id: A0A0F6TQ17
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

914150:TQ33 RS05830
gene id: 914150:TQ33_RS05830
uniprot id: A0A0F6TR92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

914150:TQ33 RS07715
gene id: 914150:TQ33_RS07715
uniprot id: A0A0F6TR91
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

914150:TQ33 RS02940
gene id: 914150:TQ33_RS02940
uniprot id: A0A0F6TPE4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

914150:TQ33 RS09505
gene id: 914150:TQ33_RS09505
uniprot id: A0A0F6RCY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

914150:TQ33 RS04730
gene id: 914150:TQ33_RS04730
uniprot id: A0A0F6RCC6
names: Similarity
messages: Belongs to the HesB/IscA family.

914150:TQ33 RS05585
gene id: 914150:TQ33_RS05585
uniprot id: A0A0F6RCI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

914150:TQ33 RS06530
gene id: 914150:TQ33_RS06530
uniprot id: A0A0F6TQM5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

914150:TQ33 RS08610
gene id: 914150:TQ33_RS08610
uniprot id: A0A0F6TS38
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

914150:TQ33 RS05900
gene id: 914150:TQ33_RS05900
uniprot id: A0A0F6RCK9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

914150:TQ33 RS08030
gene id: 914150:TQ33_RS08030
uniprot id: A0A0F6TR36
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

914150:TQ33 RS09290
gene id: 914150:TQ33_RS09290
uniprot id: A0A0F6RCW2
names: Similarity
messages: Belongs to the elongation factor P family.

914150:TQ33 RS06750
gene id: 914150:TQ33_RS06750
uniprot id: A0A0F6RCB5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

914150:TQ33 RS07430
gene id: 914150:TQ33_RS07430
uniprot id: A0A0F6TRF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

914150:TQ33 RS03555
gene id: 914150:TQ33_RS03555
uniprot id: A0A0F6RC33
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS02000
gene id: 914150:TQ33_RS02000
uniprot id: A0A0F6RBA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

914150:TQ33 RS07700
gene id: 914150:TQ33_RS07700
uniprot id: A0A0F6RCZ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

914150:TQ33 RS04955
gene id: 914150:TQ33_RS04955
uniprot id: A0A0F6TQZ5
names: Similarity
messages: Belongs to the ClpA/ClpB family.

914150:TQ33 RS02865
gene id: 914150:TQ33_RS02865
uniprot id: A0A0F6TQ74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

914150:TQ33 RS03035
gene id: 914150:TQ33_RS03035
uniprot id: A0A0F6RBZ2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

914150:TQ33 RS00685
gene id: 914150:TQ33_RS00685
uniprot id: A0A0F6TNS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MutH family.
messages: Cytoplasm
messages: Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.

914150:TQ33 RS00900
gene id: 914150:TQ33_RS00900
uniprot id: A0A0F6TP07
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.

914150:TQ33 RS10030
gene id: 914150:TQ33_RS10030
uniprot id: A0A0F6TSL5
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

914150:TQ33 RS10425
gene id: 914150:TQ33_RS10425
uniprot id: A0A0F6RDJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

914150:TQ33 RS09050
gene id: 914150:TQ33_RS09050
uniprot id: A0A0F6TRN3
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS06370
gene id: 914150:TQ33_RS06370
uniprot id: A0A0F6TQT8
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

914150:TQ33 RS10365
gene id: 914150:TQ33_RS10365
uniprot id: A0A0F6TS52
names: Similarity
messages: Belongs to the peptidase M4 family.

914150:TQ33 RS01635
gene id: 914150:TQ33_RS01635
uniprot id: A0A0F6RB77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

914150:TQ33 RS10070
gene id: 914150:TQ33_RS10070
uniprot id: A0A0F6TSL9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 3-HAO family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Homodimer.

914150:TQ33 RS04500
gene id: 914150:TQ33_RS04500
uniprot id: A0A0F6TQ60
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

914150:TQ33 RS04570
gene id: 914150:TQ33_RS04570
uniprot id: A0A0F6TPZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

914150:TQ33 RS08470
gene id: 914150:TQ33_RS08470
uniprot id: A0A0F6RCQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

914150:TQ33 RS05705
gene id: 914150:TQ33_RS05705
uniprot id: A0A0F6TQX6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

914150:TQ33 RS10705
gene id: 914150:TQ33_RS10705
uniprot id: A0A0F6RDK9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

914150:TQ33 RS06380
gene id: 914150:TQ33_RS06380
uniprot id: A0A0F6TRF2
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

914150:TQ33 RS04170
gene id: 914150:TQ33_RS04170
uniprot id: A0A0F6TPT9
names: Similarity
messages: Belongs to the PrpF family.

914150:TQ33 RS00070
gene id: 914150:TQ33_RS00070
uniprot id: A0A0F6RAV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

914150:TQ33 RS09795
gene id: 914150:TQ33_RS09795
uniprot id: A0A0F6TS01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

914150:TQ33 RS06455
gene id: 914150:TQ33_RS06455
uniprot id: A0A0F6RCQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

914150:TQ33 RS09370
gene id: 914150:TQ33_RS09370
uniprot id: A0A0F6TSF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

914150:TQ33 RS05180
gene id: 914150:TQ33_RS05180
uniprot id: A0A0F6TR17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

914150:TQ33 RS10320
gene id: 914150:TQ33_RS10320
uniprot id: A0A0F6RDI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

914150:TQ33 RS01465
gene id: 914150:TQ33_RS01465
uniprot id: A0A0F6TPS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

914150:TQ33 RS05280
gene id: 914150:TQ33_RS05280
uniprot id: A0A0F6TQ98
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

914150:TQ33 RS02315
gene id: 914150:TQ33_RS02315
uniprot id: A0A0F6TQ15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

914150:TQ33 RS02210
gene id: 914150:TQ33_RS02210
uniprot id: A0A0F6TPE1
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

914150:TQ33 RS00335
gene id: 914150:TQ33_RS00335
uniprot id: A0A0F6TP32
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS08415
gene id: 914150:TQ33_RS08415
uniprot id: A0A0F6TR83
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

914150:TQ33 RS00345
gene id: 914150:TQ33_RS00345
uniprot id: A0A0F6TNK5
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

914150:TQ33 RS06540
gene id: 914150:TQ33_RS06540
uniprot id: A0A0F6TQQ6
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

914150:TQ33 RS10805
gene id: 914150:TQ33_RS10805
uniprot id: A0A0F6TST4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

914150:TQ33 RS10640
gene id: 914150:TQ33_RS10640
uniprot id: A0A0F6RD69
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

914150:TQ33 RS03010
gene id: 914150:TQ33_RS03010
uniprot id: A0A0F6RBZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

914150:TQ33 RS10990
gene id: 914150:TQ33_RS10990
uniprot id: A0A0F6RDM9
names: Similarity
messages: Belongs to the Dps family.

914150:TQ33 RS09300
gene id: 914150:TQ33_RS09300
uniprot id: A0A0F6TRN5
names: Similarity
messages: Belongs to the catalase family.

914150:TQ33 RS06475
gene id: 914150:TQ33_RS06475
uniprot id: A0A0F6TR53
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

914150:TQ33 RS06910
gene id: 914150:TQ33_RS06910
uniprot id: A0A0F6TRA0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS03780
gene id: 914150:TQ33_RS03780
uniprot id: A0A0F6TPP1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

914150:TQ33 RS10725
gene id: 914150:TQ33_RS10725
uniprot id: A0A0F6TRZ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

914150:TQ33 RS11170
gene id: 914150:TQ33_RS11170
uniprot id: A0A0F6RDP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

914150:TQ33 RS01995
gene id: 914150:TQ33_RS01995
uniprot id: A0A0F6TP50
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

914150:TQ33 RS02320
gene id: 914150:TQ33_RS02320
uniprot id: A0A0F6RBT8
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS05570
gene id: 914150:TQ33_RS05570
uniprot id: A0A0F6RC31
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS09380
gene id: 914150:TQ33_RS09380
uniprot id: A0A0F6TS46
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

914150:TQ33 RS10795
gene id: 914150:TQ33_RS10795
uniprot id: A0A0F6TSA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

914150:TQ33 RS10155
gene id: 914150:TQ33_RS10155
uniprot id: A0A0F6TSM8
names: Similarity
messages: Belongs to the SfsA family.

914150:TQ33 RS00135
gene id: 914150:TQ33_RS00135
uniprot id: A0A0F6TNI1
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

914150:TQ33 RS07435
gene id: 914150:TQ33_RS07435
uniprot id: A0A0F6TQW5
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS09600
gene id: 914150:TQ33_RS09600
uniprot id: A0A0F6TRP5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

914150:TQ33 RS11095
gene id: 914150:TQ33_RS11095
uniprot id: A0A0F6RDN6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

914150:TQ33 RS03655
gene id: 914150:TQ33_RS03655
uniprot id: A0A0F6RC41
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

914150:TQ33 RS07990
gene id: 914150:TQ33_RS07990
uniprot id: A0A0F6TR30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

914150:TQ33 RS03005
gene id: 914150:TQ33_RS03005
uniprot id: A0A0F6TPM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

914150:TQ33 RS07530
gene id: 914150:TQ33_RS07530
uniprot id: A0A0F6TR07
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

914150:TQ33 RS07045
gene id: 914150:TQ33_RS07045
uniprot id: A0A0F6RCF0
names: Similarity
messages: Belongs to the UDPGP type 2 family.

914150:TQ33 RS04725
gene id: 914150:TQ33_RS04725
uniprot id: A0A0F6TQJ2
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

914150:TQ33 RS05555
gene id: 914150:TQ33_RS05555
uniprot id: A0A0F6TQL0
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS00985
gene id: 914150:TQ33_RS00985
uniprot id: A0A0F6TP15
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

914150:TQ33 RS07760
gene id: 914150:TQ33_RS07760
uniprot id: A0A0F6RCK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

914150:TQ33 RS04035
gene id: 914150:TQ33_RS04035
uniprot id: A0A0F6RC70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

914150:TQ33 RS04825
gene id: 914150:TQ33_RS04825
uniprot id: A0A0F6TQU3
names: Similarity
messages: Belongs to the peptidase M1 family.

914150:TQ33 RS05520
gene id: 914150:TQ33_RS05520
uniprot id: A0A0F6RC28
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

914150:TQ33 RS10650
gene id: 914150:TQ33_RS10650
uniprot id: A0A0F6TS20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

914150:TQ33 RS04600
gene id: 914150:TQ33_RS04600
uniprot id: A0A0F6TQH5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

914150:TQ33 RS06690
gene id: 914150:TQ33_RS06690
uniprot id: A0A0F6RCR8
names: Similarity
messages: Belongs to the TrpC family.
messages: Belongs to the TrpF family.

914150:TQ33 RS05050
gene id: 914150:TQ33_RS05050
uniprot id: A0A0F6RBZ3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

914150:TQ33 RS00440
gene id: 914150:TQ33_RS00440
uniprot id: A0A0F6RBE5
names: Similarity
messages: Belongs to the peptidase S8 family.

914150:TQ33 RS09535
gene id: 914150:TQ33_RS09535
uniprot id: A0A0F6TRX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

914150:TQ33 RS07380
gene id: 914150:TQ33_RS07380
uniprot id: A0A0F6TRF3
names: Cofactor
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

914150:TQ33 RS05700
gene id: 914150:TQ33_RS05700
uniprot id: A0A0F6RC42
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS01105
gene id: 914150:TQ33_RS01105
uniprot id: A0A0F6TNW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

914150:TQ33 RS07440
gene id: 914150:TQ33_RS07440
uniprot id: A0A0F6RCX9
names: Similarity
messages: Belongs to the UPF0178 family.

914150:TQ33 RS01850
gene id: 914150:TQ33_RS01850
uniprot id: A0A0F6TPP3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS10285
gene id: 914150:TQ33_RS10285
uniprot id: A0A0F6TSN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

914150:TQ33 RS09825
gene id: 914150:TQ33_RS09825
uniprot id: A0A0F6TRU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

914150:TQ33 RS05270
gene id: 914150:TQ33_RS05270
uniprot id: A0A0F6TQT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

914150:TQ33 RS08780
gene id: 914150:TQ33_RS08780
uniprot id: A0A0F6TRK7
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

914150:TQ33 RS02135
gene id: 914150:TQ33_RS02135
uniprot id: A0A0F6TPE3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

914150:TQ33 RS10140
gene id: 914150:TQ33_RS10140
uniprot id: A0A0F6RDH9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

914150:TQ33 RS06430
gene id: 914150:TQ33_RS06430
uniprot id: A0A0F6RCP8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

914150:TQ33 RS00120
gene id: 914150:TQ33_RS00120
uniprot id: A0A0F6TP73
names: Similarity
messages: Belongs to the peptidase S8 family.

914150:TQ33 RS10870
gene id: 914150:TQ33_RS10870
uniprot id: A0A0F6TS42
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

914150:TQ33 RS01480
gene id: 914150:TQ33_RS01480
uniprot id: A0A0F6TNZ6
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

914150:TQ33 RS02405
gene id: 914150:TQ33_RS02405
uniprot id: A0A0F6TQ26
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

914150:TQ33 RS08490
gene id: 914150:TQ33_RS08490
uniprot id: A0A0F6TRR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

914150:TQ33 RS09835
gene id: 914150:TQ33_RS09835
uniprot id: A0A0F6TS06
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

914150:TQ33 RS01460
gene id: 914150:TQ33_RS01460
uniprot id: A0A0F6RB53
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

914150:TQ33 RS04130
gene id: 914150:TQ33_RS04130
uniprot id: A0A0F6RC79
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

914150:TQ33 RS05010
gene id: 914150:TQ33_RS05010
uniprot id: A0A0F6RCD7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

914150:TQ33 RS10600
gene id: 914150:TQ33_RS10600
uniprot id: A0A0F6TRY5
names: Similarity
messages: Belongs to the CutA family.

914150:TQ33 RS09605
gene id: 914150:TQ33_RS09605
uniprot id: A0A0F6RCZ6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

914150:TQ33 RS06855
gene id: 914150:TQ33_RS06855
uniprot id: A0A0F6RCC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

914150:TQ33 RS08560
gene id: 914150:TQ33_RS08560
uniprot id: A0A0F6TRJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

914150:TQ33 RS07670
gene id: 914150:TQ33_RS07670
uniprot id: A0A0F6TR86
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

914150:TQ33 RS04530
gene id: 914150:TQ33_RS04530
uniprot id: A0A0F6RCB2
names: Similarity
messages: Belongs to the citrate synthase family.

914150:TQ33 RS08915
gene id: 914150:TQ33_RS08915
uniprot id: A0A0F6RD90
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

914150:TQ33 RS07665
gene id: 914150:TQ33_RS07665
uniprot id: A0A0F6TR24
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

914150:TQ33 RS00995
gene id: 914150:TQ33_RS00995
uniprot id: A0A0F6RBJ1
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

914150:TQ33 RS02655
gene id: 914150:TQ33_RS02655
uniprot id: A0A0F6RBW3
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

914150:TQ33 RS11270
gene id: 914150:TQ33_RS11270
uniprot id: A0A0F6TSX5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

914150:TQ33 RS02840
gene id: 914150:TQ33_RS02840
uniprot id: A0A0F6TPD6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

914150:TQ33 RS09195
gene id: 914150:TQ33_RS09195
uniprot id: A0A0F6RDB3
names: Similarity
messages: Belongs to the threonine synthase family.

914150:TQ33 RS08280
gene id: 914150:TQ33_RS08280
uniprot id: A0A0F6RD39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

914150:TQ33 RS01665
gene id: 914150:TQ33_RS01665
uniprot id: A0A0F6RB80
names: Similarity
messages: Belongs to the peptidase S8 family.

914150:TQ33 RS11400
gene id: 914150:TQ33_RS11400
uniprot id: A0A0F6TSF8
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

914150:TQ33 RS01400
gene id: 914150:TQ33_RS01400
uniprot id: A0A0F6RBM4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

914150:TQ33 RS08450
gene id: 914150:TQ33_RS08450
uniprot id: A0A0F6TRR3
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

914150:TQ33 RS04555
gene id: 914150:TQ33_RS04555
uniprot id: A0A0F6RCB4
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

914150:TQ33 RS01470
gene id: 914150:TQ33_RS01470
uniprot id: A0A0F6TPK0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

914150:TQ33 RS04365
gene id: 914150:TQ33_RS04365
uniprot id: A0A0F6RCA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

914150:TQ33 RS01530
gene id: 914150:TQ33_RS01530
uniprot id: A0A0F6TP72
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

914150:TQ33 RS04135
gene id: 914150:TQ33_RS04135
uniprot id: A0A0F6TPZ9
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

914150:TQ33 RS03900
gene id: 914150:TQ33_RS03900
uniprot id: A0A0F6TQH9
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

914150:TQ33 RS07690
gene id: 914150:TQ33_RS07690
uniprot id: A0A0F6TRI6
names: Similarity
messages: Belongs to the YfgM family.

914150:TQ33 RS10170
gene id: 914150:TQ33_RS10170
uniprot id: A0A0F6TRU1
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

914150:TQ33 RS01950
gene id: 914150:TQ33_RS01950
uniprot id: A0A0F6TP46
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS04690
gene id: 914150:TQ33_RS04690
uniprot id: A0A0F6RBW8
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

914150:TQ33 RS00190
gene id: 914150:TQ33_RS00190
uniprot id: A0A0F6RBC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

914150:TQ33 RS11295
gene id: 914150:TQ33_RS11295
uniprot id: A0A0F6TS90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

914150:TQ33 RS03575
gene id: 914150:TQ33_RS03575
uniprot id: A0A0F6TPW1
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

914150:TQ33 RS01775
gene id: 914150:TQ33_RS01775
uniprot id: A0A0F6TP29
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS10290
gene id: 914150:TQ33_RS10290
uniprot id: A0A0F6TSC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

914150:TQ33 RS09180
gene id: 914150:TQ33_RS09180
uniprot id: A0A0F6RCV3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

914150:TQ33 RS03510
gene id: 914150:TQ33_RS03510
uniprot id: A0A0F6TQ62
names: Similarity
messages: Belongs to the peptidase M24B family.

914150:TQ33 RS02010
gene id: 914150:TQ33_RS02010
uniprot id: A0A0F6TPD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

914150:TQ33 RS08235
gene id: 914150:TQ33_RS08235
uniprot id: A0A0F6TRP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

914150:TQ33 RS05065
gene id: 914150:TQ33_RS05065
uniprot id: A0A0F6RCE0
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

914150:TQ33 RS09065
gene id: 914150:TQ33_RS09065
uniprot id: A0A0F6TRX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

914150:TQ33 RS05660
gene id: 914150:TQ33_RS05660
uniprot id: A0A0F6TQX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

914150:TQ33 RS08205
gene id: 914150:TQ33_RS08205
uniprot id: A0A0F6RD33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

914150:TQ33 RS00630
gene id: 914150:TQ33_RS00630
uniprot id: A0A0F6RAZ8
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

914150:TQ33 RS08285
gene id: 914150:TQ33_RS08285
uniprot id: A0A0F6TR68
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

914150:TQ33 RS02280
gene id: 914150:TQ33_RS02280
uniprot id: A0A0F6RBC8
names: Function
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

914150:TQ33 RS10410
gene id: 914150:TQ33_RS10410
uniprot id: A0A0F6RD52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

914150:TQ33 RS10255
gene id: 914150:TQ33_RS10255
uniprot id: A0A0F6RD40
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

914150:TQ33 RS07390
gene id: 914150:TQ33_RS07390
uniprot id: A0A0F6TQW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

914150:TQ33 RS06780
gene id: 914150:TQ33_RS06780
uniprot id: A0A0F6TR84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

914150:TQ33 RS06450
gene id: 914150:TQ33_RS06450
uniprot id: A0A0F6TQP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

914150:TQ33 RS04940
gene id: 914150:TQ33_RS04940
uniprot id: A0A0F6TQA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

914150:TQ33 RS01805
gene id: 914150:TQ33_RS01805
uniprot id: A0A0F6RBR2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS10825
gene id: 914150:TQ33_RS10825
uniprot id: A0A0F6RD81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

914150:TQ33 RS09620
gene id: 914150:TQ33_RS09620
uniprot id: A0A0F6RDF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

914150:TQ33 RS02500
gene id: 914150:TQ33_RS02500
uniprot id: A0A0F6RBV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

914150:TQ33 RS00470
gene id: 914150:TQ33_RS00470
uniprot id: A0A0F6TNM0
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

914150:TQ33 RS11475
gene id: 914150:TQ33_RS11475
uniprot id: A0A0F6TSB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

914150:TQ33 RS06395
gene id: 914150:TQ33_RS06395
uniprot id: A0A0F6TQL1
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

914150:TQ33 RS08890
gene id: 914150:TQ33_RS08890
uniprot id: A0A0F6TRV5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

914150:TQ33 RS06785
gene id: 914150:TQ33_RS06785
uniprot id: A0A0F6TQP9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

914150:TQ33 RS10245
gene id: 914150:TQ33_RS10245
uniprot id: A0A0F6RDI5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

914150:TQ33 RS06280
gene id: 914150:TQ33_RS06280
uniprot id: A0A0F6TQS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

914150:TQ33 RS02485
gene id: 914150:TQ33_RS02485
uniprot id: A0A0F6RBE4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

914150:TQ33 RS02245
gene id: 914150:TQ33_RS02245
uniprot id: A0A0F6TP75
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

914150:TQ33 RS07750
gene id: 914150:TQ33_RS07750
uniprot id: A0A0F6RCZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

914150:TQ33 RS01580
gene id: 914150:TQ33_RS01580
uniprot id: A0A0F6TP91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

914150:TQ33 RS09610
gene id: 914150:TQ33_RS09610
uniprot id: A0A0F6TRR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

914150:TQ33 RS07475
gene id: 914150:TQ33_RS07475
uniprot id: A0A0F6RCI2
names: Caution
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS00870
gene id: 914150:TQ33_RS00870
uniprot id: A0A0F6RBI1
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

914150:TQ33 RS05525
gene id: 914150:TQ33_RS05525
uniprot id: A0A0F6TR56
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

914150:TQ33 RS01095
gene id: 914150:TQ33_RS01095
uniprot id: A0A0F6TPF6
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

914150:TQ33 RS04745
gene id: 914150:TQ33_RS04745
uniprot id: A0A0F6TQ65
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

914150:TQ33 RS11605
gene id: 914150:TQ33_RS11605
uniprot id: A0A0F6TPR7
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

914150:TQ33 RS06950
gene id: 914150:TQ33_RS06950
uniprot id: A0A0F6TRA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

914150:TQ33 RS00755
gene id: 914150:TQ33_RS00755
uniprot id: A0A0F6RB07
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

914150:TQ33 RS11395
gene id: 914150:TQ33_RS11395
uniprot id: A0A0F6RDC3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

914150:TQ33 RS00555
gene id: 914150:TQ33_RS00555
uniprot id: A0A0F6TNR0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

914150:TQ33 RS08140
gene id: 914150:TQ33_RS08140
uniprot id: A0A0F6TRY7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

914150:TQ33 RS10115
gene id: 914150:TQ33_RS10115
uniprot id: A0A0F6RDH7
names: Similarity
messages: Belongs to the peptidase M17 family.

914150:TQ33 RS07415
gene id: 914150:TQ33_RS07415
uniprot id: A0A0F6TRQ2
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

914150:TQ33 RS10090
gene id: 914150:TQ33_RS10090
uniprot id: A0A0F6RDH6
names: Function
names: Similarity
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.

914150:TQ33 RS01230
gene id: 914150:TQ33_RS01230
uniprot id: A0A0F6TNX3
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS05850
gene id: 914150:TQ33_RS05850
uniprot id: A0A0F6RCK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

914150:TQ33 RS11505
gene id: 914150:TQ33_RS11505
uniprot id: A0A0F6TS81
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

914150:TQ33 RS01515
gene id: 914150:TQ33_RS01515
uniprot id: A0A0F6TPK4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

914150:TQ33 RS10480
gene id: 914150:TQ33_RS10480
uniprot id: A0A0F6RDJ4
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

914150:TQ33 RS01485
gene id: 914150:TQ33_RS01485
uniprot id: A0A0F6RB56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

914150:TQ33 RS07965
gene id: 914150:TQ33_RS07965
uniprot id: A0A0F6TRC1
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

914150:TQ33 RS04910
gene id: 914150:TQ33_RS04910
uniprot id: A0A0F6RCD3
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

914150:TQ33 RS08545
gene id: 914150:TQ33_RS08545
uniprot id: A0A0F6TR97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

914150:TQ33 RS02235
gene id: 914150:TQ33_RS02235
uniprot id: A0A0F6TPT6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

914150:TQ33 RS06270
gene id: 914150:TQ33_RS06270
uniprot id: A0A0F6TQM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

914150:TQ33 RS05170
gene id: 914150:TQ33_RS05170
uniprot id: A0A0F6TQG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

914150:TQ33 RS04235
gene id: 914150:TQ33_RS04235
uniprot id: A0A0F6TQM2
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

914150:TQ33 RS05115
gene id: 914150:TQ33_RS05115
uniprot id: A0A0F6TQC1
names: Similarity
messages: Belongs to the asparaginase 1 family.

914150:TQ33 RS06345
gene id: 914150:TQ33_RS06345
uniprot id: A0A0F6RCP1
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

914150:TQ33 RS11510
gene id: 914150:TQ33_RS11510
uniprot id: A0A0F6RDR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

914150:TQ33 RS10890
gene id: 914150:TQ33_RS10890
uniprot id: A0A0F6TSU2
names: Similarity
messages: Belongs to the band 7/mec-2 family.

914150:TQ33 RS06995
gene id: 914150:TQ33_RS06995
uniprot id: A0A0F6TRB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

914150:TQ33 RS04360
gene id: 914150:TQ33_RS04360
uniprot id: A0A0F6TQ47
names: Similarity
messages: Belongs to the DsrF/TusC family.

914150:TQ33 RS04320
gene id: 914150:TQ33_RS04320
uniprot id: A0A0F6TQN0
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

914150:TQ33 RS05930
gene id: 914150:TQ33_RS05930
uniprot id: A0A0F6TQG2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily.

914150:TQ33 RS09250
gene id: 914150:TQ33_RS09250
uniprot id: A0A0F6TRL0
names: Similarity
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

914150:TQ33 RS08080
gene id: 914150:TQ33_RS08080
uniprot id: A0A0F6TR74
names: Similarity
messages: Belongs to the YjdM family.

914150:TQ33 RS01150
gene id: 914150:TQ33_RS01150
uniprot id: A0A0F6TNW9
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

914150:TQ33 RS09520
gene id: 914150:TQ33_RS09520
uniprot id: A0A0F6RDE4
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

914150:TQ33 RS00050
gene id: 914150:TQ33_RS00050
uniprot id: A0A0F6TNG9
names: Similarity
messages: Belongs to the IMPACT family.

914150:TQ33 RS04985
gene id: 914150:TQ33_RS04985
uniprot id: A0A0F6RCD6
names: Similarity
messages: Belongs to the peptidase S24 family.

914150:TQ33 RS05890
gene id: 914150:TQ33_RS05890
uniprot id: A0A0F6TQF9
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

914150:TQ33 RS06355
gene id: 914150:TQ33_RS06355
uniprot id: A0A0F6TQK7
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

914150:TQ33 RS09685
gene id: 914150:TQ33_RS09685
uniprot id: A0A0F6RD02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

914150:TQ33 RS07615
gene id: 914150:TQ33_RS07615
uniprot id: A0A0F6TQY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

914150:TQ33 RS01155
gene id: 914150:TQ33_RS01155
uniprot id: A0A0F6RBK4
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.

914150:TQ33 RS10460
gene id: 914150:TQ33_RS10460
uniprot id: A0A0F6TSQ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

914150:TQ33 RS01350
gene id: 914150:TQ33_RS01350
uniprot id: A0A0F6RBM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

914150:TQ33 RS07450
gene id: 914150:TQ33_RS07450
uniprot id: A0A0F6RCI0
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

914150:TQ33 RS01110
gene id: 914150:TQ33_RS01110
uniprot id: A0A0F6RB33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

914150:TQ33 RS03745
gene id: 914150:TQ33_RS03745
uniprot id: A0A0F6TPY0
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Tetramer of two alpha and two beta subunits.

914150:TQ33 RS00355
gene id: 914150:TQ33_RS00355
uniprot id: A0A0F6TNS7
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

914150:TQ33 RS08340
gene id: 914150:TQ33_RS08340
uniprot id: A0A0F6RCP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

914150:TQ33 RS05440
gene id: 914150:TQ33_RS05440
uniprot id: A0A0F6TR46
names: Similarity
messages: Belongs to the pirin family.

914150:TQ33 RS10540
gene id: 914150:TQ33_RS10540
uniprot id: A0A0F6RD61
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

914150:TQ33 RS03490
gene id: 914150:TQ33_RS03490
uniprot id: A0A0F6TPS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

914150:TQ33 RS10490
gene id: 914150:TQ33_RS10490
uniprot id: A0A0F6RD57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

914150:TQ33 RS07190
gene id: 914150:TQ33_RS07190
uniprot id: A0A0F6RCG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

914150:TQ33 RS08815
gene id: 914150:TQ33_RS08815
uniprot id: A0A0F6TRF8
names: Similarity
messages: Belongs to the peptidase U62 family.

914150:TQ33 RS05175
gene id: 914150:TQ33_RS05175
uniprot id: A0A0F6RCE7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

914150:TQ33 RS10510
gene id: 914150:TQ33_RS10510
uniprot id: A0A0F6TSE4
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

914150:TQ33 RS03460
gene id: 914150:TQ33_RS03460
uniprot id: A0A0F6TQC8
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

914150:TQ33 RS01855
gene id: 914150:TQ33_RS01855
uniprot id: A0A0F6RBR6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

914150:TQ33 RS04005
gene id: 914150:TQ33_RS04005
uniprot id: A0A0F6TPS1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

914150:TQ33 RS02600
gene id: 914150:TQ33_RS02600
uniprot id: A0A0F6TPI1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

914150:TQ33 RS08540
gene id: 914150:TQ33_RS08540
uniprot id: A0A0F6RD60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

914150:TQ33 RS08230
gene id: 914150:TQ33_RS08230
uniprot id: A0A0F6RD35
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

914150:TQ33 RS03180
gene id: 914150:TQ33_RS03180
uniprot id: A0A0F6RBJ4
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. AstD subfamily.
messages: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.

914150:TQ33 RS06520
gene id: 914150:TQ33_RS06520
uniprot id: A0A0F6RC94
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

914150:TQ33 RS04705
gene id: 914150:TQ33_RS04705
uniprot id: A0A0F6RCC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

914150:TQ33 RS04620
gene id: 914150:TQ33_RS04620
uniprot id: A0A0F6TQ50
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

914150:TQ33 RS06755
gene id: 914150:TQ33_RS06755
uniprot id: A0A0F6TQT2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

914150:TQ33 RS02095
gene id: 914150:TQ33_RS02095
uniprot id: A0A0F6TPD9
names: Similarity
messages: Belongs to the UPF0111 family.

914150:TQ33 RS10810
gene id: 914150:TQ33_RS10810
uniprot id: A0A0F6TSH4
names: Similarity
messages: Belongs to the GSP E family.

914150:TQ33 RS04335
gene id: 914150:TQ33_RS04335
uniprot id: A0A0F6RCA1
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

914150:TQ33 RS09500
gene id: 914150:TQ33_RS09500
uniprot id: A0A0F6TSH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

914150:TQ33 RS05210
gene id: 914150:TQ33_RS05210
uniprot id: A0A0F6RC05
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

914150:TQ33 RS05310
gene id: 914150:TQ33_RS05310
uniprot id: A0A0F6RC12
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

914150:TQ33 RS11245
gene id: 914150:TQ33_RS11245
uniprot id: A0A0F6TS50
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

914150:TQ33 RS03730
gene id: 914150:TQ33_RS03730
uniprot id: A0A0F6RC48
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

914150:TQ33 RS10840
gene id: 914150:TQ33_RS10840
uniprot id: A0A0F6RDL8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

914150:TQ33 RS03105
gene id: 914150:TQ33_RS03105
uniprot id: A0A0F6RBI8
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS09945
gene id: 914150:TQ33_RS09945
uniprot id: A0A0F6TSA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

914150:TQ33 RS02595
gene id: 914150:TQ33_RS02595
uniprot id: A0A0F6TPA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

914150:TQ33 RS00425
gene id: 914150:TQ33_RS00425
uniprot id: A0A0F6RAY3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

914150:TQ33 RS02845
gene id: 914150:TQ33_RS02845
uniprot id: A0A0F6TPL2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

914150:TQ33 RS08185
gene id: 914150:TQ33_RS08185
uniprot id: A0A0F6TRZ1
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

914150:TQ33 RS10040
gene id: 914150:TQ33_RS10040
uniprot id: A0A0F6RDH3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

914150:TQ33 RS01605
gene id: 914150:TQ33_RS01605
uniprot id: A0A0F6TP09
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

914150:TQ33 RS11175
gene id: 914150:TQ33_RS11175
uniprot id: A0A0F6TSD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

914150:TQ33 RS05255
gene id: 914150:TQ33_RS05255
uniprot id: A0A0F6TQH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

914150:TQ33 RS09720
gene id: 914150:TQ33_RS09720
uniprot id: A0A0F6TS84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

914150:TQ33 RS00895
gene id: 914150:TQ33_RS00895
uniprot id: A0A0F6RBI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

914150:TQ33 RS06985
gene id: 914150:TQ33_RS06985
uniprot id: A0A0F6RCE6
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS01985
gene id: 914150:TQ33_RS01985
uniprot id: A0A0F6TPQ7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

914150:TQ33 RS05565
gene id: 914150:TQ33_RS05565
uniprot id: A0A0F6TR61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

914150:TQ33 RS09530
gene id: 914150:TQ33_RS09530
uniprot id: A0A0F6RCZ1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

914150:TQ33 RS06880
gene id: 914150:TQ33_RS06880
uniprot id: A0A0F6RCC7
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

914150:TQ33 RS05390
gene id: 914150:TQ33_RS05390
uniprot id: A0A0F6RC18
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

914150:TQ33 RS10960
gene id: 914150:TQ33_RS10960
uniprot id: A0A0F6TS53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

914150:TQ33 RS06685
gene id: 914150:TQ33_RS06685
uniprot id: A0A0F6TRI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

914150:TQ33 RS06505
gene id: 914150:TQ33_RS06505
uniprot id: A0A0F6TQV3
names: Similarity
messages: Belongs to the PhzF family.

914150:TQ33 RS10770
gene id: 914150:TQ33_RS10770
uniprot id: A0A0F6RD78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

914150:TQ33 RS03335
gene id: 914150:TQ33_RS03335
uniprot id: A0A0F6RBK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

914150:TQ33 RS08295
gene id: 914150:TQ33_RS08295
uniprot id: A0A0F6TR99
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

914150:TQ33 RS00025
gene id: 914150:TQ33_RS00025
uniprot id: A0A0F6TP63
names: Similarity
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.

914150:TQ33 RS02360
gene id: 914150:TQ33_RS02360
uniprot id: A0A0F6TQ20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

914150:TQ33 RS05245
gene id: 914150:TQ33_RS05245
uniprot id: A0A0F6TQD2
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

914150:TQ33 RS02610
gene id: 914150:TQ33_RS02610
uniprot id: A0A0F6TPJ5
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

914150:TQ33 RS08605
gene id: 914150:TQ33_RS08605
uniprot id: A0A0F6TRJ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

914150:TQ33 RS06645
gene id: 914150:TQ33_RS06645
uniprot id: A0A0F6TRI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell membrane
messages: Membrane

914150:TQ33 RS09230
gene id: 914150:TQ33_RS09230
uniprot id: A0A0F6RDB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

914150:TQ33 RS00080
gene id: 914150:TQ33_RS00080
uniprot id: A0A0F6TNZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

914150:TQ33 RS07360
gene id: 914150:TQ33_RS07360
uniprot id: A0A0F6RCX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

914150:TQ33 RS04275
gene id: 914150:TQ33_RS04275
uniprot id: A0A0F6TQM6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

914150:TQ33 RS03955
gene id: 914150:TQ33_RS03955
uniprot id: A0A0F6TQA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

914150:TQ33 RS09385
gene id: 914150:TQ33_RS09385
uniprot id: A0A0F6TRM2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

914150:TQ33 RS03260
gene id: 914150:TQ33_RS03260
uniprot id: A0A0F6RBK0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS10900
gene id: 914150:TQ33_RS10900
uniprot id: A0A0F6TSI1
names: Cofactor
names: Similarity
messages: Belongs to the AspA/AstE family. Aspartoacylase subfamily.
messages: Binds 1 zinc ion per subunit.

914150:TQ33 RS04855
gene id: 914150:TQ33_RS04855
uniprot id: A0A0F6RCD1
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

914150:TQ33 RS10575
gene id: 914150:TQ33_RS10575
uniprot id: A0A0F6TS77
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

914150:TQ33 RS06235
gene id: 914150:TQ33_RS06235
uniprot id: A0A0F6TQS0
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS05380
gene id: 914150:TQ33_RS05380
uniprot id: A0A0F6RCG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

914150:TQ33 RS10470
gene id: 914150:TQ33_RS10470
uniprot id: A0A0F6TSE2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

914150:TQ33 RS00590
gene id: 914150:TQ33_RS00590
uniprot id: A0A0F6RBF8
names: Subcellular Location Annotation
messages: Nucleus

914150:TQ33 RS03440
gene id: 914150:TQ33_RS03440
uniprot id: A0A0F6TPS3
names: Function
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

914150:TQ33 RS05295
gene id: 914150:TQ33_RS05295
uniprot id: A0A0F6TQI2
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

914150:TQ33 RS11525
gene id: 914150:TQ33_RS11525
uniprot id: A0A0F6TSH1
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS01820
gene id: 914150:TQ33_RS01820
uniprot id: A0A0F6TP33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

914150:TQ33 RS02335
gene id: 914150:TQ33_RS02335
uniprot id: A0A0F6TP83
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

914150:TQ33 RS02025
gene id: 914150:TQ33_RS02025
uniprot id: A0A0F6RBA9
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

914150:TQ33 RS08485
gene id: 914150:TQ33_RS08485
uniprot id: A0A0F6RD55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

914150:TQ33 RS02370
gene id: 914150:TQ33_RS02370
uniprot id: A0A0F6RBU2
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

914150:TQ33 RS04425
gene id: 914150:TQ33_RS04425
uniprot id: A0A0F6RBU8
names: Similarity
messages: Belongs to the pyruvate kinase family.

914150:TQ33 RS05405
gene id: 914150:TQ33_RS05405
uniprot id: A0A0F6RCG7
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

914150:TQ33 RS00975
gene id: 914150:TQ33_RS00975
uniprot id: A0A0F6TNV7
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

914150:TQ33 RS01880
gene id: 914150:TQ33_RS01880
uniprot id: A0A0F6RBR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

914150:TQ33 RS09020
gene id: 914150:TQ33_RS09020
uniprot id: A0A0F6RD99
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

914150:TQ33 RS10135
gene id: 914150:TQ33_RS10135
uniprot id: A0A0F6TRW9
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS05085
gene id: 914150:TQ33_RS05085
uniprot id: A0A0F6TR08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

914150:TQ33 RS01325
gene id: 914150:TQ33_RS01325
uniprot id: A0A0F6RBL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

914150:TQ33 RS05275
gene id: 914150:TQ33_RS05275
uniprot id: A0A0F6RCF6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

914150:TQ33 RS09350
gene id: 914150:TQ33_RS09350
uniprot id: A0A0F6TRP0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

914150:TQ33 RS02015
gene id: 914150:TQ33_RS02015
uniprot id: A0A0F6RBS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

914150:TQ33 RS02110
gene id: 914150:TQ33_RS02110
uniprot id: A0A0F6TPR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

914150:TQ33 RS03720
gene id: 914150:TQ33_RS03720
uniprot id: A0A0F6TQ82
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

914150:TQ33 RS07605
gene id: 914150:TQ33_RS07605
uniprot id: A0A0F6TRH8
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS08590
gene id: 914150:TQ33_RS08590
uniprot id: A0A0F6RD64
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

914150:TQ33 RS01860
gene id: 914150:TQ33_RS01860
uniprot id: A0A0F6TP37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

914150:TQ33 RS04295
gene id: 914150:TQ33_RS04295
uniprot id: A0A0F6TPV7
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS04630
gene id: 914150:TQ33_RS04630
uniprot id: A0A0F6RCB9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS07000
gene id: 914150:TQ33_RS07000
uniprot id: A0A0F6RCU9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

914150:TQ33 RS08440
gene id: 914150:TQ33_RS08440
uniprot id: A0A0F6TS19
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

914150:TQ33 RS08760
gene id: 914150:TQ33_RS08760
uniprot id: A0A0F6RCS7
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

914150:TQ33 RS04350
gene id: 914150:TQ33_RS04350
uniprot id: A0A0F6TQ24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

914150:TQ33 RS10530
gene id: 914150:TQ33_RS10530
uniprot id: A0A0F6RDJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

914150:TQ33 RS05185
gene id: 914150:TQ33_RS05185
uniprot id: A0A0F6RC03
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS00055
gene id: 914150:TQ33_RS00055
uniprot id: A0A0F6TNP7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

914150:TQ33 RS03160
gene id: 914150:TQ33_RS03160
uniprot id: A0A0F6TQ97
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS10310
gene id: 914150:TQ33_RS10310
uniprot id: A0A0F6TRY9
names: Similarity
messages: Belongs to the DNA polymerase HolA subunit family.

914150:TQ33 RS06225
gene id: 914150:TQ33_RS06225
uniprot id: A0A0F6RC78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

914150:TQ33 RS06445
gene id: 914150:TQ33_RS06445
uniprot id: A0A0F6TQL5
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

914150:TQ33 RS00455
gene id: 914150:TQ33_RS00455
uniprot id: A0A0F6TPB6
names: Similarity
messages: Belongs to the peptidase S8 family.

914150:TQ33 RS01560
gene id: 914150:TQ33_RS01560
uniprot id: A0A0F6RB63
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

914150:TQ33 RS00330
gene id: 914150:TQ33_RS00330
uniprot id: A0A0F6TP99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

914150:TQ33 RS07400
gene id: 914150:TQ33_RS07400
uniprot id: A0A0F6TQZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

914150:TQ33 RS02410
gene id: 914150:TQ33_RS02410
uniprot id: A0A0F6RBD8
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

914150:TQ33 RS09330
gene id: 914150:TQ33_RS09330
uniprot id: A0A0F6RDC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

914150:TQ33 RS01680
gene id: 914150:TQ33_RS01680
uniprot id: A0A0F6RBQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

914150:TQ33 RS10865
gene id: 914150:TQ33_RS10865
uniprot id: A0A0F6RDL9
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS06310
gene id: 914150:TQ33_RS06310
uniprot id: A0A0F6TQN3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

914150:TQ33 RS05230
gene id: 914150:TQ33_RS05230
uniprot id: A0A0F6TQS9
names: Similarity
messages: Belongs to the fructosamine kinase family.

914150:TQ33 RS04920
gene id: 914150:TQ33_RS04920
uniprot id: A0A0F6RBY3
names: Similarity
messages: Belongs to the peptidase M16 family.

914150:TQ33 RS04980
gene id: 914150:TQ33_RS04980
uniprot id: A0A0F6TQB1
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

914150:TQ33 RS07775
gene id: 914150:TQ33_RS07775
uniprot id: A0A0F6RCZ7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

914150:TQ33 RS03880
gene id: 914150:TQ33_RS03880
uniprot id: A0A0F6RC58
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

914150:TQ33 RS03170
gene id: 914150:TQ33_RS03170
uniprot id: A0A0F6RC02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

914150:TQ33 RS06875
gene id: 914150:TQ33_RS06875
uniprot id: A0A0F6TQQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

914150:TQ33 RS09850
gene id: 914150:TQ33_RS09850
uniprot id: A0A0F6TSK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

914150:TQ33 RS10830
gene id: 914150:TQ33_RS10830
uniprot id: A0A0F6TS37
names: Similarity
messages: Belongs to the YggT family.

914150:TQ33 RS00690
gene id: 914150:TQ33_RS00690
uniprot id: A0A0F6TNY6
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

914150:TQ33 RS07335
gene id: 914150:TQ33_RS07335
uniprot id: A0A0F6RCX2
names: Similarity
messages: Belongs to the YciI family.

914150:TQ33 RS10485
gene id: 914150:TQ33_RS10485
uniprot id: A0A0F6TS05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

914150:TQ33 RS03735
gene id: 914150:TQ33_RS03735
uniprot id: A0A0F6TPV4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

914150:TQ33 RS00015
gene id: 914150:TQ33_RS00015
uniprot id: A0A0F6RAV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

914150:TQ33 RS11285
gene id: 914150:TQ33_RS11285
uniprot id: A0A0F6RDB6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

914150:TQ33 RS03065
gene id: 914150:TQ33_RS03065
uniprot id: A0A0F6RBZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

914150:TQ33 RS07495
gene id: 914150:TQ33_RS07495
uniprot id: A0A0F6TR64
names: Similarity
messages: Belongs to the RecJ family.

914150:TQ33 RS11405
gene id: 914150:TQ33_RS11405
uniprot id: A0A0F6TSY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

914150:TQ33 RS07720
gene id: 914150:TQ33_RS07720
uniprot id: A0A0F6TRT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

914150:TQ33 RS01830
gene id: 914150:TQ33_RS01830
uniprot id: A0A0F6RBR4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

914150:TQ33 RS00495
gene id: 914150:TQ33_RS00495
uniprot id: A0A0F6TPC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

914150:TQ33 RS09730
gene id: 914150:TQ33_RS09730
uniprot id: A0A0F6TRQ8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

914150:TQ33 RS06470
gene id: 914150:TQ33_RS06470
uniprot id: A0A0F6TRG2
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

914150:TQ33 RS07735
gene id: 914150:TQ33_RS07735
uniprot id: A0A0F6RCK0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS11435
gene id: 914150:TQ33_RS11435
uniprot id: A0A0F6RDR1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

914150:TQ33 RS03910
gene id: 914150:TQ33_RS03910
uniprot id: A0A0F6TQ99
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

914150:TQ33 RS08965
gene id: 914150:TQ33_RS08965
uniprot id: A0A0F6RD94
names: Similarity
messages: Belongs to the DEAD box helicase family.

914150:TQ33 RS05290
gene id: 914150:TQ33_RS05290
uniprot id: A0A0F6TQD6
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

914150:TQ33 RS00880
gene id: 914150:TQ33_RS00880
uniprot id: A0A0F6RB16
names: Similarity
messages: Belongs to the glutamate synthase family.

914150:TQ33 RS02260
gene id: 914150:TQ33_RS02260
uniprot id: A0A0F6TPF5
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

914150:TQ33 RS05515
gene id: 914150:TQ33_RS05515
uniprot id: A0A0F6TQK6
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS09840
gene id: 914150:TQ33_RS09840
uniprot id: A0A0F6RD13
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS03090
gene id: 914150:TQ33_RS03090
uniprot id: A0A0F6RBZ6
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS07215
gene id: 914150:TQ33_RS07215
uniprot id: A0A0F6RCG2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

914150:TQ33 RS01765
gene id: 914150:TQ33_RS01765
uniprot id: A0A0F6RB88
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

914150:TQ33 RS09790
gene id: 914150:TQ33_RS09790
uniprot id: A0A0F6RD10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

914150:TQ33 RS06655
gene id: 914150:TQ33_RS06655
uniprot id: A0A0F6TR71
names: Similarity
messages: Belongs to the WrbA family.

914150:TQ33 RS10895
gene id: 914150:TQ33_RS10895
uniprot id: A0A0F6RDM1
names: Similarity
messages: Belongs to the pirin family.

914150:TQ33 RS09255
gene id: 914150:TQ33_RS09255
uniprot id: A0A0F6RDB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

914150:TQ33 RS11375
gene id: 914150:TQ33_RS11375
uniprot id: A0A0F6TSM9
names: Similarity
messages: Belongs to the Lgt family.

914150:TQ33 RS00020
gene id: 914150:TQ33_RS00020
uniprot id: A0A0F6TNQ8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

914150:TQ33 RS06525
gene id: 914150:TQ33_RS06525
uniprot id: A0A0F6TR57
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS09580
gene id: 914150:TQ33_RS09580
uniprot id: A0A0F6RCZ4
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS07300
gene id: 914150:TQ33_RS07300
uniprot id: A0A0F6TRE4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

914150:TQ33 RS02690
gene id: 914150:TQ33_RS02690
uniprot id: A0A0F6TPJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

914150:TQ33 RS09145
gene id: 914150:TQ33_RS09145
uniprot id: A0A0F6RDA9
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

914150:TQ33 RS07505
gene id: 914150:TQ33_RS07505
uniprot id: A0A0F6TRR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

914150:TQ33 RS02885
gene id: 914150:TQ33_RS02885
uniprot id: A0A0F6RBH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

914150:TQ33 RS08365
gene id: 914150:TQ33_RS08365
uniprot id: A0A0F6TRQ5
names: Similarity
messages: Belongs to the MipA/OmpV family.

914150:TQ33 RS09710
gene id: 914150:TQ33_RS09710
uniprot id: A0A0F6RD04
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

914150:TQ33 RS07145
gene id: 914150:TQ33_RS07145
uniprot id: A0A0F6TQT4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

914150:TQ33 RS08685
gene id: 914150:TQ33_RS08685
uniprot id: A0A0F6RCS1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

914150:TQ33 RS06135
gene id: 914150:TQ33_RS06135
uniprot id: A0A0F6TRC8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

914150:TQ33 RS04565
gene id: 914150:TQ33_RS04565
uniprot id: A0A0F6RBV8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

914150:TQ33 RS07740
gene id: 914150:TQ33_RS07740
uniprot id: A0A0F6TQZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

914150:TQ33 RS01780
gene id: 914150:TQ33_RS01780
uniprot id: A0A0F6RBR0
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

914150:TQ33 RS08130
gene id: 914150:TQ33_RS08130
uniprot id: A0A0F6TRE1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

914150:TQ33 RS06610
gene id: 914150:TQ33_RS06610
uniprot id: A0A0F6RCR2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

914150:TQ33 RS04560
gene id: 914150:TQ33_RS04560
uniprot id: A0A0F6TQH0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

914150:TQ33 RS01550
gene id: 914150:TQ33_RS01550
uniprot id: A0A0F6RBN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

914150:TQ33 RS05140
gene id: 914150:TQ33_RS05140
uniprot id: A0A0F6TR12
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

914150:TQ33 RS05845
gene id: 914150:TQ33_RS05845
uniprot id: A0A0F6TQF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

914150:TQ33 RS03215
gene id: 914150:TQ33_RS03215
uniprot id: A0A0F6TPH2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

914150:TQ33 RS07660
gene id: 914150:TQ33_RS07660
uniprot id: A0A0F6RCJ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

914150:TQ33 RS00655
gene id: 914150:TQ33_RS00655
uniprot id: A0A0F6RB00
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

914150:TQ33 RS08555
gene id: 914150:TQ33_RS08555
uniprot id: A0A0F6TRC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

914150:TQ33 RS00010
gene id: 914150:TQ33_RS00010
uniprot id: A0A0F6TNP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

914150:TQ33 RS09680
gene id: 914150:TQ33_RS09680
uniprot id: A0A0F6TS79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

914150:TQ33 RS06010
gene id: 914150:TQ33_RS06010
uniprot id: A0A0F6TR06
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

914150:TQ33 RS11745
gene id: 914150:TQ33_RS11745
uniprot id: A0A0F6RBE2
names: Similarity
messages: Belongs to the ketopantoate reductase family.

914150:TQ33 RS03055
gene id: 914150:TQ33_RS03055
uniprot id: A0A0F6TPN3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

914150:TQ33 RS09360
gene id: 914150:TQ33_RS09360
uniprot id: A0A0F6RDC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

914150:TQ33 RS02195
gene id: 914150:TQ33_RS02195
uniprot id: A0A0F6TPT3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

914150:TQ33 RS06830
gene id: 914150:TQ33_RS06830
uniprot id: A0A0F6TQQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Monomer.

914150:TQ33 RS01520
gene id: 914150:TQ33_RS01520
uniprot id: A0A0F6TP00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

914150:TQ33 RS07130
gene id: 914150:TQ33_RS07130
uniprot id: A0A0F6TRL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RfaH family.
messages: Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components.
messages: Interacts with both the nontemplate DNA and the RNA polymerase (RNAP).

914150:TQ33 RS07405
gene id: 914150:TQ33_RS07405
uniprot id: A0A0F6TR55
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

914150:TQ33 RS05250
gene id: 914150:TQ33_RS05250
uniprot id: A0A0F6RCF4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

914150:TQ33 RS10190
gene id: 914150:TQ33_RS10190
uniprot id: A0A0F6RDI2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

914150:TQ33 RS02630
gene id: 914150:TQ33_RS02630
uniprot id: A0A0F6RBW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

914150:TQ33 RS03835
gene id: 914150:TQ33_RS03835
uniprot id: A0A0F6TPP8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

914150:TQ33 RS11340
gene id: 914150:TQ33_RS11340
uniprot id: A0A0F6TS62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

914150:TQ33 RS06650
gene id: 914150:TQ33_RS06650
uniprot id: A0A0F6RCA5
names: Similarity
messages: Belongs to the ArsC family.

914150:TQ33 RS11535
gene id: 914150:TQ33_RS11535
uniprot id: A0A0F6RDR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

914150:TQ33 RS08655
gene id: 914150:TQ33_RS08655
uniprot id: A0A0F6TRJ8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

914150:TQ33 RS11485
gene id: 914150:TQ33_RS11485
uniprot id: A0A0F6RDR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

914150:TQ33 RS03550
gene id: 914150:TQ33_RS03550
uniprot id: A0A0F6TQ66
names: Similarity
messages: Belongs to the IucA/IucC family.

914150:TQ33 RS03025
gene id: 914150:TQ33_RS03025
uniprot id: A0A0F6TQ87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0283 family.
messages: Cell inner membrane
messages: Membrane

914150:TQ33 RS11430
gene id: 914150:TQ33_RS11430
uniprot id: A0A0F6TSA6
names: Subcellular Location Annotation
messages: Periplasm

914150:TQ33 RS06005
gene id: 914150:TQ33_RS06005
uniprot id: A0A0F6RCL7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS10520
gene id: 914150:TQ33_RS10520
uniprot id: A0A0F6TRX6
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

914150:TQ33 RS10660
gene id: 914150:TQ33_RS10660
uniprot id: A0A0F6TS87
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

914150:TQ33 RS03165
gene id: 914150:TQ33_RS03165
uniprot id: A0A0F6TQ31
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

914150:TQ33 RS02005
gene id: 914150:TQ33_RS02005
uniprot id: A0A0F6TPB7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

914150:TQ33 RS08495
gene id: 914150:TQ33_RS08495
uniprot id: A0A0F6RCQ7
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS05445
gene id: 914150:TQ33_RS05445
uniprot id: A0A0F6RC22
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

914150:TQ33 RS01250
gene id: 914150:TQ33_RS01250
uniprot id: A0A0F6RBL2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

914150:TQ33 RS10720
gene id: 914150:TQ33_RS10720
uniprot id: A0A0F6TSG5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

914150:TQ33 RS03190
gene id: 914150:TQ33_RS03190
uniprot id: A0A0F6TPR1
names: Caution
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

914150:TQ33 RS00650
gene id: 914150:TQ33_RS00650
uniprot id: A0A0F6TNY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

914150:TQ33 RS04845
gene id: 914150:TQ33_RS04845
uniprot id: A0A0F6TQ23
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS00970
gene id: 914150:TQ33_RS00970
uniprot id: A0A0F6RBI9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

914150:TQ33 RS02225
gene id: 914150:TQ33_RS02225
uniprot id: A0A0F6RBC4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS05315
gene id: 914150:TQ33_RS05315
uniprot id: A0A0F6TQT9
names: Similarity
messages: Belongs to the peptidase S8 family.

914150:TQ33 RS02115
gene id: 914150:TQ33_RS02115
uniprot id: A0A0F6RBS7
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

914150:TQ33 RS02740
gene id: 914150:TQ33_RS02740
uniprot id: A0A0F6RBG3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

914150:TQ33 RS01065
gene id: 914150:TQ33_RS01065
uniprot id: A0A0F6TP24
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

914150:TQ33 RS11075
gene id: 914150:TQ33_RS11075
uniprot id: A0A0F6TS31
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

914150:TQ33 RS10445
gene id: 914150:TQ33_RS10445
uniprot id: A0A0F6TS02
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS07655
gene id: 914150:TQ33_RS07655
uniprot id: A0A0F6TQY6
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

914150:TQ33 RS00245
gene id: 914150:TQ33_RS00245
uniprot id: A0A0F6TP88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

914150:TQ33 RS09575
gene id: 914150:TQ33_RS09575
uniprot id: A0A0F6TRX5
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS06100
gene id: 914150:TQ33_RS06100
uniprot id: A0A0F6RC71
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

914150:TQ33 RS06020
gene id: 914150:TQ33_RS06020
uniprot id: A0A0F6TQH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

914150:TQ33 RS04685
gene id: 914150:TQ33_RS04685
uniprot id: A0A0F6TQI6
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

914150:TQ33 RS06960
gene id: 914150:TQ33_RS06960
uniprot id: A0A0F6TQR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

914150:TQ33 RS09135
gene id: 914150:TQ33_RS09135
uniprot id: A0A0F6TRP3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

914150:TQ33 RS05260
gene id: 914150:TQ33_RS05260
uniprot id: A0A0F6RC08
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

914150:TQ33 RS07695
gene id: 914150:TQ33_RS07695
uniprot id: A0A0F6TQZ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

914150:TQ33 RS06085
gene id: 914150:TQ33_RS06085
uniprot id: A0A0F6TQQ8
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

914150:TQ33 RS10055
gene id: 914150:TQ33_RS10055
uniprot id: A0A0F6TRV9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

914150:TQ33 RS05855
gene id: 914150:TQ33_RS05855
uniprot id: A0A0F6TQJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

914150:TQ33 RS04010
gene id: 914150:TQ33_RS04010
uniprot id: A0A0F6RC68
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

914150:TQ33 RS09335
gene id: 914150:TQ33_RS09335
uniprot id: A0A0F6TRL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

914150:TQ33 RS01725
gene id: 914150:TQ33_RS01725
uniprot id: A0A0F6TPN0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

914150:TQ33 RS04550
gene id: 914150:TQ33_RS04550
uniprot id: A0A0F6TQQ5
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

914150:TQ33 RS06825
gene id: 914150:TQ33_RS06825
uniprot id: A0A0F6RCC3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

914150:TQ33 RS02325
gene id: 914150:TQ33_RS02325
uniprot id: A0A0F6TPU7
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

914150:TQ33 RS10455
gene id: 914150:TQ33_RS10455
uniprot id: A0A0F6RDJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

914150:TQ33 RS00550
gene id: 914150:TQ33_RS00550
uniprot id: A0A0F6RAZ2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

914150:TQ33 RS06295
gene id: 914150:TQ33_RS06295
uniprot id: A0A0F6TR33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

914150:TQ33 RS00940
gene id: 914150:TQ33_RS00940
uniprot id: A0A0F6TP11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

914150:TQ33 RS09645
gene id: 914150:TQ33_RS09645
uniprot id: A0A0F6TRQ1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

914150:TQ33 RS11350
gene id: 914150:TQ33_RS11350
uniprot id: A0A0F6TS94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

914150:TQ33 RS11695
gene id: 914150:TQ33_RS11695
uniprot id: A0A0F6TS99
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

914150:TQ33 RS04915
gene id: 914150:TQ33_RS04915
uniprot id: A0A0F6TQZ0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

914150:TQ33 RS04015
gene id: 914150:TQ33_RS04015
uniprot id: A0A0F6TPY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

914150:TQ33 RS08020
gene id: 914150:TQ33_RS08020
uniprot id: A0A0F6TRL7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS07745
gene id: 914150:TQ33_RS07745
uniprot id: A0A0F6TR34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

914150:TQ33 RS04960
gene id: 914150:TQ33_RS04960
uniprot id: A0A0F6RCD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

914150:TQ33 RS03245
gene id: 914150:TQ33_RS03245
uniprot id: A0A0F6TQA7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

914150:TQ33 RS09570
gene id: 914150:TQ33_RS09570
uniprot id: A0A0F6RDE7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS02350
gene id: 914150:TQ33_RS02350
uniprot id: A0A0F6TPG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

914150:TQ33 RS11480
gene id: 914150:TQ33_RS11480
uniprot id: A0A0F6TSG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

914150:TQ33 RS06770
gene id: 914150:TQ33_RS06770
uniprot id: A0A0F6TRJ3
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

914150:TQ33 RS01495
gene id: 914150:TQ33_RS01495
uniprot id: A0A0F6TP85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

914150:TQ33 RS08475
gene id: 914150:TQ33_RS08475
uniprot id: A0A0F6TRI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

914150:TQ33 RS04090
gene id: 914150:TQ33_RS04090
uniprot id: A0A0F6TPS6
names: Similarity
messages: Belongs to the MlaA family.

914150:TQ33 RS00480
gene id: 914150:TQ33_RS00480
uniprot id: A0A0F6TNU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

914150:TQ33 RS07340
gene id: 914150:TQ33_RS07340
uniprot id: A0A0F6TRE9
names: Similarity
messages: Belongs to the BolA/IbaG family.

914150:TQ33 RS03875
gene id: 914150:TQ33_RS03875
uniprot id: A0A0F6TPQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

914150:TQ33 RS00710
gene id: 914150:TQ33_RS00710
uniprot id: A0A0F6TPI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

914150:TQ33 RS06920
gene id: 914150:TQ33_RS06920
uniprot id: A0A0F6RCU3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

914150:TQ33 RS04190
gene id: 914150:TQ33_RS04190
uniprot id: A0A0F6RBR5
names: Similarity
messages: Belongs to the PrpD family.

914150:TQ33 RS00885
gene id: 914150:TQ33_RS00885
uniprot id: A0A0F6TPD7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

914150:TQ33 RS11440
gene id: 914150:TQ33_RS11440
uniprot id: A0A0F6TSG2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

914150:TQ33 RS06215
gene id: 914150:TQ33_RS06215
uniprot id: A0A0F6RCN2
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

914150:TQ33 RS08895
gene id: 914150:TQ33_RS08895
uniprot id: A0A0F6RCT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

914150:TQ33 RS10440
gene id: 914150:TQ33_RS10440
uniprot id: A0A0F6RD54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

914150:TQ33 RS06695
gene id: 914150:TQ33_RS06695
uniprot id: A0A0F6TR75
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS07100
gene id: 914150:TQ33_RS07100
uniprot id: A0A0F6RCF3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

914150:TQ33 RS10935
gene id: 914150:TQ33_RS10935
uniprot id: A0A0F6TSU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

914150:TQ33 RS03845
gene id: 914150:TQ33_RS03845
uniprot id: A0A0F6TPW6
names: Similarity
messages: Belongs to the peptidase S8 family.

914150:TQ33 RS03710
gene id: 914150:TQ33_RS03710
uniprot id: A0A0F6TQG0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

914150:TQ33 RS01320
gene id: 914150:TQ33_RS01320
uniprot id: A0A0F6TP51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

914150:TQ33 RS07555
gene id: 914150:TQ33_RS07555
uniprot id: A0A0F6RCI7
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS01630
gene id: 914150:TQ33_RS01630
uniprot id: A0A0F6TPU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

914150:TQ33 RS00955
gene id: 914150:TQ33_RS00955
uniprot id: A0A0F6RB22
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

914150:TQ33 RS03740
gene id: 914150:TQ33_RS03740
uniprot id: A0A0F6RBN6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

914150:TQ33 RS06935
gene id: 914150:TQ33_RS06935
uniprot id: A0A0F6TQZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

914150:TQ33 RS07840
gene id: 914150:TQ33_RS07840
uniprot id: A0A0F6TRU7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

914150:TQ33 RS02590
gene id: 914150:TQ33_RS02590
uniprot id: A0A0F6RBF2
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

914150:TQ33 RS10265
gene id: 914150:TQ33_RS10265
uniprot id: A0A0F6TRY4
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

914150:TQ33 RS08670
gene id: 914150:TQ33_RS08670
uniprot id: A0A0F6TRT2
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

914150:TQ33 RS04900
gene id: 914150:TQ33_RS04900
uniprot id: A0A0F6TQA4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

914150:TQ33 RS07205
gene id: 914150:TQ33_RS07205
uniprot id: A0A0F6RCW3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

914150:TQ33 RS08905
gene id: 914150:TQ33_RS08905
uniprot id: A0A0F6TRG7
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

914150:TQ33 RS08155
gene id: 914150:TQ33_RS08155
uniprot id: A0A0F6TR52
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

914150:TQ33 RS08245
gene id: 914150:TQ33_RS08245
uniprot id: A0A0F6TR63
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

914150:TQ33 RS09885
gene id: 914150:TQ33_RS09885
uniprot id: A0A0F6TRR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

914150:TQ33 RS01340
gene id: 914150:TQ33_RS01340
uniprot id: A0A0F6TPQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

914150:TQ33 RS02330
gene id: 914150:TQ33_RS02330
uniprot id: A0A0F6RBD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

914150:TQ33 RS06205
gene id: 914150:TQ33_RS06205
uniprot id: A0A0F6TRD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

914150:TQ33 RS00510
gene id: 914150:TQ33_RS00510
uniprot id: A0A0F6TNM5
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

914150:TQ33 RS00660
gene id: 914150:TQ33_RS00660
uniprot id: A0A0F6TP03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

914150:TQ33 RS05045
gene id: 914150:TQ33_RS05045
uniprot id: A0A0F6TR05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

914150:TQ33 RS11025
gene id: 914150:TQ33_RS11025
uniprot id: A0A0F6RD96
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

914150:TQ33 RS09560
gene id: 914150:TQ33_RS09560
uniprot id: A0A0F6TRN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS10175
gene id: 914150:TQ33_RS10175
uniprot id: A0A0F6RD34
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

914150:TQ33 RS05320
gene id: 914150:TQ33_RS05320
uniprot id: A0A0F6TQA2
names: Similarity
messages: Belongs to the peptidase S8 family.

914150:TQ33 RS08275
gene id: 914150:TQ33_RS08275
uniprot id: A0A0F6TRP6
names: Similarity
messages: Belongs to the peptidase S8 family.

914150:TQ33 RS05715
gene id: 914150:TQ33_RS05715
uniprot id: A0A0F6RCJ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

914150:TQ33 RS00835
gene id: 914150:TQ33_RS00835
uniprot id: A0A0F6TPJ6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

914150:TQ33 RS09325
gene id: 914150:TQ33_RS09325
uniprot id: A0A0F6TS41
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

914150:TQ33 RS08000
gene id: 914150:TQ33_RS08000
uniprot id: A0A0F6RD16
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS08445
gene id: 914150:TQ33_RS08445
uniprot id: A0A0F6RCQ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

914150:TQ33 RS11795
gene id: 914150:TQ33_RS11795
uniprot id: A0A0F6TSP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

914150:TQ33 RS06315
gene id: 914150:TQ33_RS06315
uniprot id: A0A0F6RCP0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

914150:TQ33 RS07140
gene id: 914150:TQ33_RS07140
uniprot id: A0A0F6RCV8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

914150:TQ33 RS05835
gene id: 914150:TQ33_RS05835
uniprot id: A0A0F6RC51
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

914150:TQ33 RS09555
gene id: 914150:TQ33_RS09555
uniprot id: A0A0F6RCZ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

914150:TQ33 RS08565
gene id: 914150:TQ33_RS08565
uniprot id: A0A0F6RD62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

914150:TQ33 RS00530
gene id: 914150:TQ33_RS00530
uniprot id: A0A0F6TNW3
names: Function
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.

914150:TQ33 RS02175
gene id: 914150:TQ33_RS02175
uniprot id: A0A0F6RBC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

914150:TQ33 RS00430
gene id: 914150:TQ33_RS00430
uniprot id: A0A0F6TNL4
names: Similarity
messages: Belongs to the peptidase S8 family.

914150:TQ33 RS08600
gene id: 914150:TQ33_RS08600
uniprot id: A0A0F6RCR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

914150:TQ33 RS08995
gene id: 914150:TQ33_RS08995
uniprot id: A0A0F6TRH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

914150:TQ33 RS11325
gene id: 914150:TQ33_RS11325
uniprot id: A0A0F6TSX7
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

914150:TQ33 RS01060
gene id: 914150:TQ33_RS01060
uniprot id: A0A0F6TNW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

914150:TQ33 RS03715
gene id: 914150:TQ33_RS03715
uniprot id: A0A0F6RBN4
names: Similarity
messages: Belongs to the Gfa family.

914150:TQ33 RS04305
gene id: 914150:TQ33_RS04305
uniprot id: A0A0F6RC99
names: Similarity
messages: Belongs to the peptidase C40 family.

914150:TQ33 RS07885
gene id: 914150:TQ33_RS07885
uniprot id: A0A0F6TRV2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

914150:TQ33 RS09735
gene id: 914150:TQ33_RS09735
uniprot id: A0A0F6RD06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

914150:TQ33 RS07210
gene id: 914150:TQ33_RS07210
uniprot id: A0A0F6TRD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

914150:TQ33 RS11030
gene id: 914150:TQ33_RS11030
uniprot id: A0A0F6TS27
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

914150:TQ33 RS10315
gene id: 914150:TQ33_RS10315
uniprot id: A0A0F6TS49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

914150:TQ33 RS11150
gene id: 914150:TQ33_RS11150
uniprot id: A0A0F6TSK6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

914150:TQ33 RS11590
gene id: 914150:TQ33_RS11590
uniprot id: A0A0F6RBW5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

914150:TQ33 RS06110
gene id: 914150:TQ33_RS06110
uniprot id: A0A0F6TQI3
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

914150:TQ33 RS09690
gene id: 914150:TQ33_RS09690
uniprot id: A0A0F6TRQ6
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

914150:TQ33 RS09510
gene id: 914150:TQ33_RS09510
uniprot id: A0A0F6TS60
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

914150:TQ33 RS05950
gene id: 914150:TQ33_RS05950
uniprot id: A0A0F6RCL2
names: Similarity
messages: Belongs to the peptidase S9C family.

914150:TQ33 RS07960
gene id: 914150:TQ33_RS07960
uniprot id: A0A0F6RCL6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

914150:TQ33 RS07410
gene id: 914150:TQ33_RS07410
uniprot id: A0A0F6RCX7
names: Function
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.

914150:TQ33 RS03000
gene id: 914150:TQ33_RS03000
uniprot id: A0A0F6TPE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

914150:TQ33 RS03535
gene id: 914150:TQ33_RS03535
uniprot id: A0A0F6TPV5
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

914150:TQ33 RS00935
gene id: 914150:TQ33_RS00935
uniprot id: A0A0F6TNV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

914150:TQ33 RS00760
gene id: 914150:TQ33_RS00760
uniprot id: A0A0F6TPC5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

914150:TQ33 RS05540
gene id: 914150:TQ33_RS05540
uniprot id: A0A0F6TQC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

914150:TQ33 RS02815
gene id: 914150:TQ33_RS02815
uniprot id: A0A0F6TPL7
names: Similarity
messages: Belongs to the peptidase S51 family.

914150:TQ33 RS04645
gene id: 914150:TQ33_RS04645
uniprot id: A0A0F6TQI1
names: Similarity
messages: Belongs to the transglycosylase Slt family.

914150:TQ33 RS07105
gene id: 914150:TQ33_RS07105
uniprot id: A0A0F6TQT0
names: Similarity
messages: Belongs to the polysaccharide synthase family.

914150:TQ33 RS03070
gene id: 914150:TQ33_RS03070
uniprot id: A0A0F6TQ90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

914150:TQ33 RS07200
gene id: 914150:TQ33_RS07200
uniprot id: A0A0F6TRM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

914150:TQ33 RS10465
gene id: 914150:TQ33_RS10465
uniprot id: A0A0F6RD56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

914150:TQ33 RS09025
gene id: 914150:TQ33_RS09025
uniprot id: A0A0F6TRX1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

914150:TQ33 RS05885
gene id: 914150:TQ33_RS05885
uniprot id: A0A0F6RC55
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

914150:TQ33 RS04265
gene id: 914150:TQ33_RS04265
uniprot id: A0A0F6RBT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

914150:TQ33 RS09830
gene id: 914150:TQ33_RS09830
uniprot id: A0A0F6RDG3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

914150:TQ33 RS03500
gene id: 914150:TQ33_RS03500
uniprot id: A0A0F6TPU8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

914150:TQ33 RS09700
gene id: 914150:TQ33_RS09700
uniprot id: A0A0F6RDF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

914150:TQ33 RS04155
gene id: 914150:TQ33_RS04155
uniprot id: A0A0F6RC81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

914150:TQ33 RS07040
gene id: 914150:TQ33_RS07040
uniprot id: A0A0F6TRL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

914150:TQ33 RS00230
gene id: 914150:TQ33_RS00230
uniprot id: A0A0F6TNR2
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS10665
gene id: 914150:TQ33_RS10665
uniprot id: A0A0F6RD70
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

914150:TQ33 RS10195
gene id: 914150:TQ33_RS10195
uniprot id: A0A0F6TSN0
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS01685
gene id: 914150:TQ33_RS01685
uniprot id: A0A0F6TPM5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

914150:TQ33 RS00845
gene id: 914150:TQ33_RS00845
uniprot id: A0A0F6RBH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

914150:TQ33 RS05400
gene id: 914150:TQ33_RS05400
uniprot id: A0A0F6TQV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

914150:TQ33 RS09175
gene id: 914150:TQ33_RS09175
uniprot id: A0A0F6TRP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

914150:TQ33 RS03085
gene id: 914150:TQ33_RS03085
uniprot id: A0A0F6TPF8
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS01075
gene id: 914150:TQ33_RS01075
uniprot id: A0A0F6TP44
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

914150:TQ33 RS01070
gene id: 914150:TQ33_RS01070
uniprot id: A0A0F6RBJ7
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

914150:TQ33 RS09440
gene id: 914150:TQ33_RS09440
uniprot id: A0A0F6RDD2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

914150:TQ33 RS09540
gene id: 914150:TQ33_RS09540
uniprot id: A0A0F6TSH7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

914150:TQ33 RS01645
gene id: 914150:TQ33_RS01645
uniprot id: A0A0F6TPM0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS09800
gene id: 914150:TQ33_RS09800
uniprot id: A0A0F6TSK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

914150:TQ33 RS05535
gene id: 914150:TQ33_RS05535
uniprot id: A0A0F6RCH7
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

914150:TQ33 RS10390
gene id: 914150:TQ33_RS10390
uniprot id: A0A0F6TRW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

914150:TQ33 RS09340
gene id: 914150:TQ33_RS09340
uniprot id: A0A0F6RCW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

914150:TQ33 RS02555
gene id: 914150:TQ33_RS02555
uniprot id: A0A0F6RBV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

914150:TQ33 RS07385
gene id: 914150:TQ33_RS07385
uniprot id: A0A0F6RCX6
names: Similarity
messages: Belongs to the HisA/HisF family.

914150:TQ33 RS07730
gene id: 914150:TQ33_RS07730
uniprot id: A0A0F6TRJ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

914150:TQ33 RS04045
gene id: 914150:TQ33_RS04045
uniprot id: A0A0F6RBQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

914150:TQ33 RS05365
gene id: 914150:TQ33_RS05365
uniprot id: A0A0F6RC16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

914150:TQ33 RS03220
gene id: 914150:TQ33_RS03220
uniprot id: A0A0F6RC07
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

914150:TQ33 RS08840
gene id: 914150:TQ33_RS08840
uniprot id: A0A0F6RCT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

914150:TQ33 RS02505
gene id: 914150:TQ33_RS02505
uniprot id: A0A0F6TPA0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

914150:TQ33 RS01845
gene id: 914150:TQ33_RS01845
uniprot id: A0A0F6TPW3
names: Similarity
messages: Belongs to the UPF0758 family.

914150:TQ33 RS03325
gene id: 914150:TQ33_RS03325
uniprot id: A0A0F6RC15
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

914150:TQ33 RS00805
gene id: 914150:TQ33_RS00805
uniprot id: A0A0F6RB11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

914150:TQ33 RS01795
gene id: 914150:TQ33_RS01795
uniprot id: A0A0F6TPB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

914150:TQ33 RS07230
gene id: 914150:TQ33_RS07230
uniprot id: A0A0F6RCW5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

914150:TQ33 RS08025
gene id: 914150:TQ33_RS08025
uniprot id: A0A0F6RD17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

914150:TQ33 RS07680
gene id: 914150:TQ33_RS07680
uniprot id: A0A0F6TRS9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

914150:TQ33 RS03175
gene id: 914150:TQ33_RS03175
uniprot id: A0A0F6TPG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

914150:TQ33 RS08050
gene id: 914150:TQ33_RS08050
uniprot id: A0A0F6RD20
names: Subcellular Location Annotation
messages: Cytoplasm

914150:TQ33 RS05370
gene id: 914150:TQ33_RS05370
uniprot id: A0A0F6TQA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

914150:TQ33 RS05040
gene id: 914150:TQ33_RS05040
uniprot id: A0A0F6RCD9
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

914150:TQ33 RS02440
gene id: 914150:TQ33_RS02440
uniprot id: A0A0F6TPH1
names: Similarity
messages: Belongs to the nitroreductase family. HadB/RutE subfamily.

914150:TQ33 RS10670
gene id: 914150:TQ33_RS10670
uniprot id: A0A0F6TSS3
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

914150:TQ33 RS09955
gene id: 914150:TQ33_RS09955
uniprot id: A0A0F6RDG8
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

914150:TQ33 RS00920
gene id: 914150:TQ33_RS00920
uniprot id: A0A0F6RBI5
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

914150:TQ33 RS10675
gene id: 914150:TQ33_RS10675
uniprot id: A0A0F6TSG0
names: Similarity
messages: Belongs to the GARS family.

914150:TQ33 RS09810
gene id: 914150:TQ33_RS09810
uniprot id: A0A0F6TS95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

914150:TQ33 RS05360
gene id: 914150:TQ33_RS05360
uniprot id: A0A0F6TQU5
names: Similarity
messages: Belongs to the peptidase S41A family.

914150:TQ33 RS00875
gene id: 914150:TQ33_RS00875
uniprot id: A0A0F6TPK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

914150:TQ33 RS11280
gene id: 914150:TQ33_RS11280
uniprot id: A0A0F6TSM1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

914150:TQ33 RS06420
gene id: 914150:TQ33_RS06420
uniprot id: A0A0F6TQU2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

914150:TQ33 RS03475
gene id: 914150:TQ33_RS03475
uniprot id: A0A0F6TQ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

914150:TQ33 RS04935
gene id: 914150:TQ33_RS04935
uniprot id: A0A0F6RCD4
names: Similarity
messages: Belongs to the UPF0339 family. Duplicated subfamily.

914150:TQ33 RS07065
gene id: 914150:TQ33_RS07065
uniprot id: A0A0F6RCV2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

914150:TQ33 RS02730
gene id: 914150:TQ33_RS02730
uniprot id: A0A0F6TPJ8
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS06810
gene id: 914150:TQ33_RS06810
uniprot id: A0A0F6TRJ7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

914150:TQ33 RS04835
gene id: 914150:TQ33_RS04835
uniprot id: A0A0F6TQK4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS01215
gene id: 914150:TQ33_RS01215
uniprot id: A0A0F6TPN7
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS08705
gene id: 914150:TQ33_RS08705
uniprot id: A0A0F6TS48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

914150:TQ33 RS05265
gene id: 914150:TQ33_RS05265
uniprot id: A0A0F6TR27
names: Similarity
messages: Belongs to the fabD family.

914150:TQ33 RS07955
gene id: 914150:TQ33_RS07955
uniprot id: A0A0F6TR59
names: Subcellular Location Annotation
messages: Cytoplasm

914150:TQ33 RS10475
gene id: 914150:TQ33_RS10475
uniprot id: A0A0F6TRX2
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

914150:TQ33 RS01405
gene id: 914150:TQ33_RS01405
uniprot id: A0A0F6TP60
names: Similarity
messages: Belongs to the band 7/mec-2 family.

914150:TQ33 RS01115
gene id: 914150:TQ33_RS01115
uniprot id: A0A0F6TP30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

914150:TQ33 RS09245
gene id: 914150:TQ33_RS09245
uniprot id: A0A0F6TS25
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

914150:TQ33 RS02540
gene id: 914150:TQ33_RS02540
uniprot id: A0A0F6TPW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

914150:TQ33 RS11760
gene id: 914150:TQ33_RS11760
uniprot id: A0A0F6TQE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

914150:TQ33 RS02625
gene id: 914150:TQ33_RS02625
uniprot id: A0A0F6TPX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

914150:TQ33 RS00705
gene id: 914150:TQ33_RS00705
uniprot id: A0A0F6RB03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

914150:TQ33 RS08715
gene id: 914150:TQ33_RS08715
uniprot id: A0A0F6TRT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

914150:TQ33 RS08850
gene id: 914150:TQ33_RS08850
uniprot id: A0A0F6TRD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

914150:TQ33 RS05545
gene id: 914150:TQ33_RS05545
uniprot id: A0A0F6RC30
names: Similarity
messages: Belongs to the UPF0434 family.

914150:TQ33 RS00790
gene id: 914150:TQ33_RS00790
uniprot id: A0A0F6TPJ1
names: Similarity
messages: Belongs to the RutC family.

914150:TQ33 RS02050
gene id: 914150:TQ33_RS02050
uniprot id: A0A0F6RBB0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

914150:TQ33 RS07895
gene id: 914150:TQ33_RS07895
uniprot id: A0A0F6RD07
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

914150:TQ33 RS01655
gene id: 914150:TQ33_RS01655
uniprot id: A0A0F6RBQ1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

914150:TQ33 RS03125
gene id: 914150:TQ33_RS03125
uniprot id: A0A0F6TQ28
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Multifunctional regulator of fatty acid metabolism.

914150:TQ33 RS10110
gene id: 914150:TQ33_RS10110
uniprot id: A0A0F6TSM3
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

914150:TQ33 RS09900
gene id: 914150:TQ33_RS09900
uniprot id: A0A0F6TS10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

914150:TQ33 RS11470
gene id: 914150:TQ33_RS11470
uniprot id: A0A0F6RDC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

914150:TQ33 RS06930
gene id: 914150:TQ33_RS06930
uniprot id: A0A0F6RCE2
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

914150:TQ33 RS01080
gene id: 914150:TQ33_RS01080
uniprot id: A0A0F6RB31
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

914150:TQ33 RS02020
gene id: 914150:TQ33_RS02020
uniprot id: A0A0F6TPY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

914150:TQ33 RS10420
gene id: 914150:TQ33_RS10420
uniprot id: A0A0F6TSD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

914150:TQ33 RS00285
gene id: 914150:TQ33_RS00285
uniprot id: A0A0F6TP94
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

914150:TQ33 RS01345
gene id: 914150:TQ33_RS01345
uniprot id: A0A0F6TPI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

914150:TQ33 RS09665
gene id: 914150:TQ33_RS09665
uniprot id: A0A0F6TRY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

914150:TQ33 RS08675
gene id: 914150:TQ33_RS08675
uniprot id: A0A0F6RD71
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

914150:TQ33 RS03540
gene id: 914150:TQ33_RS03540
uniprot id: A0A0F6RBM1
names: Similarity
messages: Belongs to the IucA/IucC family.

914150:TQ33 RS05985
gene id: 914150:TQ33_RS05985
uniprot id: A0A0F6TQK5
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

914150:TQ33 RS10395
gene id: 914150:TQ33_RS10395
uniprot id: A0A0F6TRZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

914150:TQ33 RS04970
gene id: 914150:TQ33_RS04970
uniprot id: A0A0F6RBY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

914150:TQ33 RS04165
gene id: 914150:TQ33_RS04165
uniprot id: A0A0F6RBR3
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

914150:TQ33 RS02030
gene id: 914150:TQ33_RS02030
uniprot id: A0A0F6TPR2
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

914150:TQ33 RS02580
gene id: 914150:TQ33_RS02580
uniprot id: A0A0F6RBV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

914150:TQ33 RS04440
gene id: 914150:TQ33_RS04440
uniprot id: A0A0F6RCA7
names: Similarity
messages: Belongs to the peptidase S9C family.

914150:TQ33 RS06765
gene id: 914150:TQ33_RS06765
uniprot id: A0A0F6RCS4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

914150:TQ33 RS10875
gene id: 914150:TQ33_RS10875
uniprot id: A0A0F6RD85
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

914150:TQ33 RS11035
gene id: 914150:TQ33_RS11035
uniprot id: A0A0F6TS61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

914150:TQ33 RS08755
gene id: 914150:TQ33_RS08755
uniprot id: A0A0F6TRU2
names: Subcellular Location Annotation
messages: Membrane

914150:TQ33 RS05785
gene id: 914150:TQ33_RS05785
uniprot id: A0A0F6TQY5
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

914150:TQ33 RS04220
gene id: 914150:TQ33_RS04220
uniprot id: A0A0F6TQ08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

914150:TQ33 RS07460
gene id: 914150:TQ33_RS07460
uniprot id: A0A0F6TRQ7
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.