9135:MRPS17
gene id: 9135:MRPS17
uniprot id: A0A8C9MW20
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

9135:C1H12orf57
gene id: 9135:C1H12orf57
uniprot id: A0A8C9NMT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0456 family.
messages: Cytoplasm

9135:LOC103820122
gene id: 9135:LOC103820122
uniprot id: A0A8C9MKJ2
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

9135:HSF4
gene id: 9135:HSF4
uniprot id: A0A8C9MQD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

9135:ADRA1D
gene id: 9135:ADRA1D
uniprot id: A0A8C9N423
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with FLNA (via filamin repeat 21); increases PKA-mediated phosphorylation of FLNA.
messages: Membrane
messages: This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.

9135:STAT4
gene id: 9135:STAT4
uniprot id: A0A8C9MJ66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

9135:TRNT1
gene id: 9135:TRNT1
uniprot id: A0A8C9NF60
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

9135:LOC103823737
gene id: 9135:LOC103823737
uniprot id: A0A8C9NRL1
names: Subcellular Location Annotation
messages: Secreted

9135:LOC103819811
gene id: 9135:LOC103819811
uniprot id: A0A8C9NHN2
names: Similarity
messages: Belongs to the NDK family.

9135:PPM1L
gene id: 9135:PPM1L
uniprot id: A0A8C9N5R7
names: Similarity
messages: Belongs to the PP2C family.

9135:MTMR4
gene id: 9135:MTMR4
uniprot id: A0A8C9MMF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm
messages: Membrane

9135:RAB32
gene id: 9135:RAB32
uniprot id: A0A8C9MGI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

9135:KCNMB4
gene id: 9135:KCNMB4
uniprot id: A0A8C9N1B1
names: Subcellular Location Annotation
messages: Membrane

9135:LOC103819081
gene id: 9135:LOC103819081
uniprot id: A0A8C9MFX0
names: Similarity
messages: Belongs to the serpin family.

9135:DGKD
gene id: 9135:DGKD
uniprot id: A0A8C9MI75
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

9135:STAG2
gene id: 9135:STAG2
uniprot id: A0A8C9UI58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

9135:ZFYVE9
gene id: 9135:ZFYVE9
uniprot id: A0A8C9MSG0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Early endosome membrane

9135:CHAF1B
gene id: 9135:CHAF1B
uniprot id: A0A8C9N8Q3
names: Subcellular Location Annotation
messages: Nucleus

9135:FAM83F
gene id: 9135:FAM83F
uniprot id: A0A8C9MQF4
names: Similarity
messages: Belongs to the FAM83 family.

9135:AMZ1
gene id: 9135:AMZ1
uniprot id: A0A8C9N1H4
names: Function
names: Similarity
messages: Belongs to the peptidase M54 family.
messages: Probable zinc metalloprotease.

9135:SLC25A24
gene id: 9135:SLC25A24
uniprot id: A0A8C9NE00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

9135:GINS2
gene id: 9135:GINS2
uniprot id: A0A8C9MU29
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS2/PSF2 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus

9135:OSBPL5
gene id: 9135:OSBPL5
uniprot id: A0A8C9MN98
names: Similarity
messages: Belongs to the OSBP family.

9135:RIDA
gene id: 9135:RIDA
uniprot id: A0A8C9MKW2
names: Function
names: Similarity
messages: Belongs to the RutC family.
messages: Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase.

9135:TBCE
gene id: 9135:TBCE
uniprot id: A0A8C9U7P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCE family.
messages: Cytoplasm

9135:BCHE
gene id: 9135:BCHE
uniprot id: A0A8C9UD72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Secreted

9135:ATP2A2
gene id: 9135:ATP2A2
uniprot id: A0A8C9UDK9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

9135:GGA2
gene id: 9135:GGA2
uniprot id: A0A8C9U5L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

9135:LOC103817747
gene id: 9135:LOC103817747
uniprot id: A0A8C9UFC5
names: Similarity
messages: Belongs to the globin family.

9135:PSAP
gene id: 9135:PSAP
uniprot id: A0A8C9UID4
names: Function
names: Subcellular Location Annotation
messages: Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.
messages: Saposins are specific low-molecular mass non-enzymic proteins, they participate in the lysosomal degradation of sphingolipids, which takes place by the sequential action of specific hydrolases.
messages: Secreted

9135:RAB9B
gene id: 9135:RAB9B
uniprot id: A0A8C9NVZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: phagosome membrane

9135:LAMA4
gene id: 9135:LAMA4
uniprot id: A0A8C9NMJ8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

9135:STXBP5L
gene id: 9135:STXBP5L
uniprot id: A0A8C9N8R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat L(2)GL family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

9135:PEX5
gene id: 9135:PEX5
uniprot id: A0A8C9NPF1
names: Similarity
messages: Belongs to the peroxisomal targeting signal receptor family.

9135:NDUFA8
gene id: 9135:NDUFA8
uniprot id: A0A8C9L1C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA8 subunit family.
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

9135:KIN
gene id: 9135:KIN
uniprot id: A0A8C9N463
names: Similarity
messages: Belongs to the KIN17 family.

9135:HOGA1
gene id: 9135:HOGA1
uniprot id: A0A8C9NTI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the final step in the metabolic pathway of hydroxyproline.
messages: Homotetramer.

9135:C4H4orf48
gene id: 9135:C4H4orf48
uniprot id: A0A8C9NPF7
names: Subcellular Location Annotation
messages: Secreted

9135:BMP5
gene id: 9135:BMP5
uniprot id: A0A8C9N9W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

9135:HAAO
gene id: 9135:HAAO
uniprot id: A0A8C9N5K4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 3-HAO family.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

9135:ACOX2
gene id: 9135:ACOX2
uniprot id: A0A8C9U9M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

9135:HSBP1
gene id: 9135:HSBP1
uniprot id: A0A8C9MVG0
names: Similarity
messages: Belongs to the HSBP1 family.

9135:ZDHHC1
gene id: 9135:ZDHHC1
uniprot id: A0A8C9MSG6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9135:LOC103820555
gene id: 9135:LOC103820555
uniprot id: A0A8C9NA76
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Converted into plasmin by plasminogen activators, both plasminogen and its activator being bound to fibrin.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells.
messages: Secreted

9135:OPRL1
gene id: 9135:OPRL1
uniprot id: A0A8C9NPL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin.
messages: Membrane
messages: Vesicle

9135:NOP58
gene id: 9135:NOP58
uniprot id: A0A8C9MG34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

9135:IL18
gene id: 9135:IL18
uniprot id: A0A8C9MWM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Cytoplasm
messages: Secreted

9135:WDR24
gene id: 9135:WDR24
uniprot id: A0A8C9NG50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR24 family.
messages: Lysosome membrane

9135:MAT1A
gene id: 9135:MAT1A
uniprot id: A0A8C9MHW9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

9135:MINDY2
gene id: 9135:MINDY2
uniprot id: A0A8C9KNX8
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM63 subfamily.
messages: Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins. Has exodeubiquitinase activity and has a preference for long polyubiquitin chains. May play a regulatory role at the level of protein turnover.

9135:RAD51
gene id: 9135:RAD51
uniprot id: A0A8C9NAX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Nucleus
messages: Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR). Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Recruited to resolve stalled replication forks during replication stress. Also involved in interstrand cross-link repair.

9135:CPLX4
gene id: 9135:CPLX4
uniprot id: A0A8C9MHK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

9135:MAP3K7
gene id: 9135:MAP3K7
uniprot id: A0A8C9KYJ9
uniprot id: A0A8C9L3E4
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

9135:TPD52
gene id: 9135:TPD52
uniprot id: A0A8C9MFU5
names: Similarity
messages: Belongs to the TPD52 family.

9135:HSPA4
gene id: 9135:HSPA4
uniprot id: A0A8C9KXG7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 70 family.
messages: Cytoplasm
messages: Interacts with TJP1/ZO-1.

9135:RFFL
gene id: 9135:RFFL
uniprot id: A0A8C9MTH2
uniprot id: A0A8C9MV39
names: Subcellular Location Annotation
messages: Cell membrane

9135:LLPH
gene id: 9135:LLPH
uniprot id: A0A8C9MGY2
names: Similarity
messages: Belongs to the learning-associated protein family.

9135:LPAR6
gene id: 9135:LPAR6
uniprot id: A0A8C9NIC7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9135:TMOD1
gene id: 9135:TMOD1
uniprot id: A0A8C9NA02
names: Subcellular Location Annotation
messages: cytoskeleton

9135:AP3B2
gene id: 9135:AP3B2
uniprot id: A0A8C9NS22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes large subunit family.
messages: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
messages: clathrin-coated vesicle membrane

9135:WDR48
gene id: 9135:WDR48
uniprot id: A0A8C9MTR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR48 family.
messages: Late endosome

9135:ABHD3
gene id: 9135:ABHD3
uniprot id: A0A8C9N9M7
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

9135:LMBR1L
gene id: 9135:LMBR1L
uniprot id: A0A8C9NM09
names: Similarity
messages: Belongs to the LIMR family.

9135:B9D1
gene id: 9135:B9D1
uniprot id: A0A8C9N2Y7
names: Subcellular Location Annotation
messages: cilium basal body

9135:KIFC3
gene id: 9135:KIFC3
uniprot id: A0A8C9MUB1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9135:GATA3
gene id: 9135:GATA3
uniprot id: A0A8C9N783
names: Subcellular Location Annotation
messages: Nucleus

9135:ABAT
gene id: 9135:ABAT
uniprot id: A0A8C9NB72
names: Similarity
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer; disulfide-linked.

9135:FAM161B
gene id: 9135:FAM161B
uniprot id: A0A8C9N9S3
names: Similarity
messages: Belongs to the FAM161 family.

9135:ASRGL1
gene id: 9135:ASRGL1
uniprot id: A0A8C9N0I1
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

9135:SASS6
gene id: 9135:SASS6
uniprot id: A0A8C9UFK1
names: Subcellular Location Annotation
messages: centrosome

9135:AZIN1
gene id: 9135:AZIN1
uniprot id: A0A8C9U9G7
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

9135:SPSB4
gene id: 9135:SPSB4
uniprot id: A0A8C9MHW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

9135:LOC103823377
gene id: 9135:LOC103823377
uniprot id: A0A8C9MFP7
names: Function
names: Similarity
messages: Belongs to the janus family.
messages: Exhibits phosphohistidine phosphatase activity.

9135:MTIF2
gene id: 9135:MTIF2
uniprot id: A0A8C9UGA9
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

9135:TXLNA
gene id: 9135:TXLNA
uniprot id: A0A8C9MP77
names: Similarity
messages: Belongs to the taxilin family.

9135:TSSC4
gene id: 9135:TSSC4
uniprot id: A0A8C9U716
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TSSC4 family.
messages: Cytoplasm
messages: Nucleus

9135:TACR1
gene id: 9135:TACR1
uniprot id: A0A8C9NP46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9135:HTR2A
gene id: 9135:HTR2A
uniprot id: A0A8C9NII0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin).
messages: Membrane
messages: Presynapse
messages: Synapse
messages: Vesicle
messages: axon
messages: caveola
messages: dendrite

9135:RNASET2
gene id: 9135:RNASET2
uniprot id: A0A8C9NAC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase T2 family.
messages: Lysosome lumen

9135:NPBWR1
gene id: 9135:NPBWR1
uniprot id: A0A8C9NID9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9135:ATP6V1H
gene id: 9135:ATP6V1H
uniprot id: A0A8C9UFU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase H subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

9135:LOC103821893
gene id: 9135:LOC103821893
uniprot id: A0A8C9U6Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dienelactone hydrolase family.
messages: cytosol

9135:EIF6
gene id: 9135:EIF6
uniprot id: A0A8C9NAG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-6 family.
messages: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.
messages: Cytoplasm
messages: Monomer. Associates with the 60S ribosomal subunit.
messages: nucleolus

9135:UTP18
gene id: 9135:UTP18
uniprot id: A0A8C9NP45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat UTP18 family.
messages: nucleolus

9135:MFGE8
gene id: 9135:MFGE8
uniprot id: A0A8C9MRS4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:CENPI
gene id: 9135:CENPI
uniprot id: A0A8C9NT41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-I/CTF3 family.
messages: Nucleus
messages: centromere

9135:AQP3
gene id: 9135:AQP3
uniprot id: A0A8C9UHV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

9135:CEMIP
gene id: 9135:CEMIP
uniprot id: A0A8C9U9Z9
names: Similarity
messages: Belongs to the CEMIP family.

9135:ANKZF1
gene id: 9135:ANKZF1
uniprot id: A0A8C9NL10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKZF1/VMS1 family.
messages: Cytoplasm

9135:ZDHHC6
gene id: 9135:ZDHHC6
uniprot id: A0A8C9UHC8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9135:GLYR1
gene id: 9135:GLYR1
uniprot id: A0A8C9MH37
uniprot id: A0A8C9MH91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HIBADH-related family. NP60 subfamily.
messages: Belongs to the rogdi family.
messages: Chromosome
messages: Presynapse
messages: Vesicle
messages: synaptic vesicle

9135:LOC103822817
gene id: 9135:LOC103822817
uniprot id: A0A8C9NRV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

9135:SLC51A
gene id: 9135:SLC51A
uniprot id: A0A8C9NIZ9
names: Subcellular Location Annotation
messages: Membrane

9135:SCRN3
gene id: 9135:SCRN3
uniprot id: A0A8C9UI32
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

9135:GSTZ1
gene id: 9135:GSTZ1
uniprot id: A0A8C9UDE7
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

9135:CXXC5
gene id: 9135:CXXC5
uniprot id: A0A8C9N1I1
names: Subcellular Location Annotation
messages: Cytoplasm

9135:UIMC1
gene id: 9135:UIMC1
uniprot id: A0A8C9NJ33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAP80 family.
messages: Nucleus

9135:BNIP1
gene id: 9135:BNIP1
uniprot id: A0A8C9NPG8
names: Subcellular Location Annotation
messages: Membrane

9135:LOC103818038
gene id: 9135:LOC103818038
uniprot id: A0A8C9MLB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

9135:STRADB
gene id: 9135:STRADB
uniprot id: A0A8C9MGJ1
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.

9135:UBA3
gene id: 9135:UBA3
uniprot id: A0A8C9MYU7
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
messages: Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.

9135:SUDS3
gene id: 9135:SUDS3
uniprot id: A0A8C9U7S4
names: Subcellular Location Annotation
messages: Nucleus

9135:LOC103823724
gene id: 9135:LOC103823724
uniprot id: A0A8C9NT74
names: Similarity
messages: Belongs to the hexokinase family.

9135:CORIN
gene id: 9135:CORIN
uniprot id: A0A8C9MYK8
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:BCL2L13
gene id: 9135:BCL2L13
uniprot id: A0A8C9MS21
names: Similarity
messages: Belongs to the Bcl-2 family.

9135:MAPKAPK3
gene id: 9135:MAPKAPK3
uniprot id: A0A8C9KWC2
names: Similarity
messages: Belongs to the protein kinase superfamily.

9135:PPIL4
gene id: 9135:PPIL4
uniprot id: A0A8C9N1I4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.
messages: Nucleus
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

9135:LECT2
gene id: 9135:LECT2
uniprot id: A0A8C9N8F3
names: Similarity
messages: Belongs to the LECT2/MIM-1 family.

9135:GPR39
gene id: 9135:GPR39
uniprot id: A0A8C9N990
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9135:EEF1AKMT2
gene id: 9135:EEF1AKMT2
uniprot id: A0A8C9UGC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.
messages: Cytoplasm
messages: Nucleus
messages: Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'.

9135:LOC103812325
gene id: 9135:LOC103812325
uniprot id: A0A8C9NSD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

9135:PAMR1
gene id: 9135:PAMR1
uniprot id: A0A8C9MJW0
uniprot id: A0A8C9MK27
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:ANAPC4
gene id: 9135:ANAPC4
uniprot id: A0A8C9MMX1
names: Function
names: Similarity
messages: Belongs to the APC4 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.

9135:TEK
gene id: 9135:TEK
uniprot id: A0A8C9N825
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9135:GRK7
gene id: 9135:GRK7
uniprot id: A0A8C9ME69
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

9135:LOC103823540
gene id: 9135:LOC103823540
uniprot id: A0A8C9N140
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

9135:SLC52A3
gene id: 9135:SLC52A3
uniprot id: A0A8C9UGF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

9135:TXLNB
gene id: 9135:TXLNB
uniprot id: A0A8C9MI48
names: Similarity
messages: Belongs to the taxilin family.

9135:PSPC1
gene id: 9135:PSPC1
uniprot id: A0A8C9MQS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PSPC family.
messages: Cytoplasm
messages: Nucleus matrix
messages: Nucleus speckle
messages: nucleolus

9135:PSMF1
gene id: 9135:PSMF1
uniprot id: A0A8C9UGF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proteasome inhibitor PI31 family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28.

9135:SLC34A2
gene id: 9135:SLC34A2
uniprot id: A0A8C9MP72
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Membrane

9135:LOC103819677
gene id: 9135:LOC103819677
uniprot id: A0A8C9MY64
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

9135:REV1
gene id: 9135:REV1
uniprot id: A0A8C9NTZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-Y family.
messages: Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
messages: Nucleus

9135:ACTR8
gene id: 9135:ACTR8
uniprot id: A0A8C9U2X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the actin family. ARP8 subfamily.
messages: Chromosome
messages: Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the DBINO domain of INO80. Exists as monomers and dimers, but the dimer is most probably the biologically relevant form required for stable interactions with histones that exploits the twofold symmetry of the nucleosome core.
messages: Nucleus
messages: Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize.
messages: Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.

9135:ACAA2
gene id: 9135:ACAA2
uniprot id: A0A8C9NUB3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

9135:PHYHIPL
gene id: 9135:PHYHIPL
uniprot id: A0A8C9MJU9
names: Similarity
messages: Belongs to the PHYHIP family.

9135:CHRNA9
gene id: 9135:CHRNA9
uniprot id: A0A8C9MQI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9135:SCAMP4
gene id: 9135:SCAMP4
uniprot id: A0A8C9KUM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

9135:PWP2
gene id: 9135:PWP2
uniprot id: A0A8C9UEB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PWP2 family.
messages: nucleolus

9135:RHBDD1
gene id: 9135:RHBDD1
uniprot id: A0A8C9KSP7
names: Subcellular Location Annotation
messages: Membrane

9135:TRAF2
gene id: 9135:TRAF2
uniprot id: A0A8C9N9M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

9135:CDC37L1
gene id: 9135:CDC37L1
uniprot id: A0A8C9KSH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

9135:MMP2
gene id: 9135:MMP2
uniprot id: A0A8C9MPG3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.
messages: extracellular matrix

9135:GALR1
gene id: 9135:GALR1
uniprot id: A0A8C9MWL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

9135:PRICKLE1
gene id: 9135:PRICKLE1
uniprot id: A0A8C9NJF4
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

9135:CTLA4
gene id: 9135:CTLA4
uniprot id: A0A8C9MF82
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
messages: Membrane

9135:ST7
gene id: 9135:ST7
uniprot id: A0A8C9N5E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ST7 family.
messages: Membrane

9135:RBP1
gene id: 9135:RBP1
uniprot id: A0A8C9N4S3
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

9135:AGTR1
gene id: 9135:AGTR1
uniprot id: A0A8C9NNM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C.

9135:TOP2B
gene id: 9135:TOP2B
uniprot id: A0A8C9NNT4
uniprot id: A0A8C9NPY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Homodimer.
messages: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand.
messages: nucleolus
messages: nucleoplasm

9135:SMARCAL1
gene id: 9135:SMARCAL1
uniprot id: A0A8C9NHA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.
messages: Nucleus

9135:FGF1
gene id: 9135:FGF1
uniprot id: A0A8C9L6A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: Nucleus
messages: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling.
messages: Secreted
messages: cell cortex
messages: cytosol

9135:EVX1
gene id: 9135:EVX1
uniprot id: A0A8C9NPQ8
names: Subcellular Location Annotation
messages: Nucleus

9135:SMAD3
gene id: 9135:SMAD3
uniprot id: A0A8C9UE68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

9135:CDCA7L
gene id: 9135:CDCA7L
uniprot id: A0A8C9NN99
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9135:HLF
gene id: 9135:HLF
uniprot id: A0A8C9NNC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

9135:EXOC2
gene id: 9135:EXOC2
uniprot id: A0A8C9L4H9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SEC5 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: Component of the exocyst complex.

9135:HACD4
gene id: 9135:HACD4
uniprot id: A0A8C9KXH9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9135:CDCA8
gene id: 9135:CDCA8
uniprot id: A0A8C9NQI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the borealin family.
messages: centromere

9135:HGD
gene id: 9135:HGD
uniprot id: A0A8C9N2Z2
uniprot id: A0A8C9N718
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

9135:ANPEP
gene id: 9135:ANPEP
uniprot id: A0A8C9NL29
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

9135:CASQ2
gene id: 9135:CASQ2
uniprot id: A0A8C9N6M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsequestrin family.
messages: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.
messages: Sarcoplasmic reticulum lumen

9135:PGK1
gene id: 9135:PGK1
uniprot id: A0A8C9NU98
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

9135:ROPN1L
gene id: 9135:ROPN1L
uniprot id: A0A8C9MMV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ropporin family.
messages: flagellum

9135:CMTM6
gene id: 9135:CMTM6
uniprot id: A0A8C9MDS6
names: Subcellular Location Annotation
messages: Membrane

9135:LIPH
gene id: 9135:LIPH
uniprot id: A0A8C9MRH5
uniprot id: A0A8C9MRU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

9135:JUN
gene id: 9135:JUN
uniprot id: P54864
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family. Jun subfamily.
messages: Interacts with FOS to form a dimer.
messages: Nucleus
messages: Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. May be involved in activated KRAS-mediated transcriptional activation of USP28. May bind to the USP28 promoter.

9135:ACAD11
gene id: 9135:ACAD11
uniprot id: A0A8C9L4Z0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

9135:MCM8
gene id: 9135:MCM8
uniprot id: A0A8C9KQ56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

9135:TMEM178B
gene id: 9135:TMEM178B
uniprot id: A0A8C9N4H7
names: Similarity
messages: Belongs to the TMEM178 family.

9135:CER1
gene id: 9135:CER1
uniprot id: A0A8C9L411
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9135:HEXD
gene id: 9135:HEXD
uniprot id: A0A8C9U471
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

9135:LOC108961555
gene id: 9135:LOC108961555
uniprot id: A0A8C9UBC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9135:APLP2
gene id: 9135:APLP2
uniprot id: A0A8C9NWM3
uniprot id: A0A8C9NYB0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9135:LOC103826034
gene id: 9135:LOC103826034
uniprot id: A0A8C9NK54
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

9135:EHF
gene id: 9135:EHF
uniprot id: A0A8C9MKA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9135:CNR2
gene id: 9135:CNR2
uniprot id: A0A8C9MU94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9135:GPR55
gene id: 9135:GPR55
uniprot id: A0A8C9NW76
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9135:PPP4R3A
gene id: 9135:PPP4R3A
uniprot id: A0A8C9N0H8
names: Similarity
messages: Belongs to the SMEK family.

9135:UGDH
gene id: 9135:UGDH
uniprot id: A0A8C9U8M7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
messages: Homohexamer.
messages: Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate.

9135:STK17A
gene id: 9135:STK17A
uniprot id: A0A8C9NSA2
names: Similarity
messages: Belongs to the protein kinase superfamily.

9135:PRTFDC1
gene id: 9135:PRTFDC1
uniprot id: A0A8C9UDU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

9135:PI4K2B
gene id: 9135:PI4K2B
uniprot id: A0A8C9MMS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
messages: Membrane

9135:OGN
gene id: 9135:OGN
uniprot id: A0A8C9NEA5
names: Similarity
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.

9135:SEPTIN2
gene id: 9135:SEPTIN2
uniprot id: A0A8C9MYK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Midbody
messages: cilium membrane
messages: spindle

9135:OPRK1
gene id: 9135:OPRK1
uniprot id: A0A8C9UFB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain. Plays a role in mediating reduced physical activity upon treatment with synthetic opioids. Plays a role in the regulation of salivation in response to synthetic opioids. May play a role in arousal and regulation of autonomic and neuroendocrine functions.
messages: Interacts with NHERF1. Interacts with GABARAPL1.
messages: Membrane

9135:DIABLO
gene id: 9135:DIABLO
uniprot id: A0A8C9N5K2
names: Subcellular Location Annotation
messages: Mitochondrion

9135:GJB1
gene id: 9135:GJB1
uniprot id: A0A8C9NV40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Beta-type (group I) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9135:NMD3
gene id: 9135:NMD3
uniprot id: A0A8C9N404
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
messages: Belongs to the NMD3 family.
messages: Cytoplasm
messages: Nucleus

9135:LOC103819249
gene id: 9135:LOC103819249
uniprot id: A0A8C9NL09
names: Similarity
messages: Belongs to the PRORSD1 family.

9135:CKAP2L
gene id: 9135:CKAP2L
uniprot id: A0A8C9NSP0
names: Similarity
messages: Belongs to the CKAP2 family.

9135:MBTD1
gene id: 9135:MBTD1
uniprot id: A0A8C9NP55
names: Subcellular Location Annotation
messages: Nucleus

9135:RSL24D1
gene id: 9135:RSL24D1
uniprot id: A0A8C9KV87
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

9135:LOC108962077
gene id: 9135:LOC108962077
uniprot id: A0A8C9ML15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the C19orf12 family.
messages: Mitochondrion membrane

9135:SNX1
gene id: 9135:SNX1
uniprot id: A0A8C9NRZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: lamellipodium
messages: trans-Golgi network membrane

9135:SLC7A2
gene id: 9135:SLC7A2
uniprot id: A0A8C9N462
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

9135:NDST2
gene id: 9135:NDST2
uniprot id: A0A8C9KUV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

9135:ENTPD5
gene id: 9135:ENTPD5
uniprot id: A0A8C9UE31
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

9135:SMN1
gene id: 9135:SMN1
uniprot id: A0A8C9NGM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMN family.
messages: Cajal body
messages: Perikaryon
messages: Z line
messages: gem
messages: neuron projection

9135:SLC14A1
gene id: 9135:SLC14A1
uniprot id: A0A8C9NUS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

9135:CNIH1
gene id: 9135:CNIH1
uniprot id: A0A8C9MFG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

9135:LOC103820504
gene id: 9135:LOC103820504
uniprot id: A0A8C9MHE4
names: Similarity
messages: Belongs to the ARTD/PARP family.

9135:PROK2
gene id: 9135:PROK2
uniprot id: A0A8C9N1C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AVIT (prokineticin) family.
messages: Secreted

9135:GINS4
gene id: 9135:GINS4
uniprot id: A0A8C9NXQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GINS4/SLD5 family.
messages: Chromosome
messages: Nucleus
messages: Required for initiation of chromosomal DNA replication. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.

9135:LOC103822739
gene id: 9135:LOC103822739
uniprot id: A0A8C9NX38
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:MARF1
gene id: 9135:MARF1
uniprot id: A0A8C9UEV7
names: Subcellular Location Annotation
messages: Peroxisome

9135:GET1
gene id: 9135:GET1
uniprot id: A0A8C9NBB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WRB/GET1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9135:HAO2
gene id: 9135:HAO2
uniprot id: A0A8C9N8C0
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

9135:KCTD20
gene id: 9135:KCTD20
uniprot id: A0A8C9NH58
names: Subcellular Location Annotation
messages: Cytoplasm

9135:GHRH
gene id: 9135:GHRH
uniprot id: A0A8C9NF72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

9135:DDX5
gene id: 9135:DDX5
uniprot id: A0A8C9NLT7
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.

9135:LOC103821679
gene id: 9135:LOC103821679
uniprot id: A0A8C9UEA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

9135:LOC103818637
gene id: 9135:LOC103818637
uniprot id: A0A8C9NH78
uniprot id: A0A8C9NHN4
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

9135:C7H2orf76
gene id: 9135:C7H2orf76
uniprot id: A0A8C9N806
names: Similarity
messages: Belongs to the UPF0538 family.

9135:ALPL
gene id: 9135:ALPL
uniprot id: A0A8C9MKE0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

9135:VPS4B
gene id: 9135:VPS4B
uniprot id: A0A8C9MG21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

9135:FOXN2
gene id: 9135:FOXN2
uniprot id: A0A8C9UFA1
names: Subcellular Location Annotation
messages: Nucleus

9135:RPLP0
gene id: 9135:RPLP0
uniprot id: A0A8C9MLW2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Ribosomal protein P0 is the functional equivalent of E.coli protein L10.

9135:SF3B3
gene id: 9135:SF3B3
uniprot id: A0A8C9MRR0
names: Subcellular Location Annotation
messages: Nucleus

9135:COG6
gene id: 9135:COG6
uniprot id: A0A8C9NH63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COG6 family.
messages: Component of the conserved oligomeric Golgi complex which is composed of eight different subunits and is required for normal Golgi morphology and localization.
messages: Golgi apparatus membrane
messages: Membrane
messages: Required for normal Golgi function.

9135:ESR1
gene id: 9135:ESR1
uniprot id: A0A8C9NCZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.

9135:USP20
gene id: 9135:USP20
uniprot id: A0A8C9MNG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP20/USP33 subfamily.
messages: centrosome
messages: perinuclear region

9135:RFX3
gene id: 9135:RFX3
uniprot id: A0A8C9MI86
names: Subcellular Location Annotation
messages: Nucleus

9135:LOC103827286
gene id: 9135:LOC103827286
uniprot id: A0A8C9U7B4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

9135:VIPR2
gene id: 9135:VIPR2
uniprot id: A0A8C9N105
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

9135:NTNG2
gene id: 9135:NTNG2
uniprot id: A0A8C9U5T9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:SLC66A1
gene id: 9135:SLC66A1
uniprot id: A0A8C9KXV0
names: Subcellular Location Annotation
messages: Membrane

9135:DEGS1
gene id: 9135:DEGS1
uniprot id: A0A8C9NQG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

9135:ADORA2B
gene id: 9135:ADORA2B
uniprot id: A0A8C9N558
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

9135:SEMA5B
gene id: 9135:SEMA5B
uniprot id: A0A8C9NCS5
uniprot id: A0A8C9NEX4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:LOC103814228
gene id: 9135:LOC103814228
uniprot id: A0A8C9U5W4
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

9135:DOCK9
gene id: 9135:DOCK9
uniprot id: A0A8C9NMF1
names: Similarity
messages: Belongs to the DOCK family.

9135:MOV10
gene id: 9135:MOV10
uniprot id: A0A8C9NNP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
messages: P-body

9135:CEP76
gene id: 9135:CEP76
uniprot id: A0A8C9MZQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP76 family.
messages: Centrosomal protein involved in regulation of centriole duplication. Required to limit centriole duplication to once per cell cycle by preventing centriole reduplication.
messages: centriole

9135:CSNK1A1
gene id: 9135:CSNK1A1
uniprot id: A0A8C9KWX4
uniprot id: A0A8C9L633
names: Similarity
messages: Belongs to the protein kinase superfamily.

9135:LIG4
gene id: 9135:LIG4
uniprot id: A0A8C9NS17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

9135:SEMA4D
gene id: 9135:SEMA4D
uniprot id: A0A8C9NLU2
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:TINAG
gene id: 9135:TINAG
uniprot id: A0A8C9NCC2
names: Similarity
messages: Belongs to the peptidase C1 family.

9135:NOG
gene id: 9135:NOG
uniprot id: A0A8C9NNW1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the noggin family.
messages: Homodimer.
messages: Secreted

9135:HMOX2
gene id: 9135:HMOX2
uniprot id: A0A8C9NG80
names: Similarity
messages: Belongs to the heme oxygenase family.

9135:TWSG1
gene id: 9135:TWSG1
uniprot id: A0A8C9N458
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the twisted gastrulation protein family.
messages: Secreted

9135:GALNT7
gene id: 9135:GALNT7
uniprot id: A0A8C9N6T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9135:DPH3
gene id: 9135:DPH3
uniprot id: A0A8C9NMC3
names: Similarity
messages: Belongs to the DPH3 family.

9135:TNFAIP6
gene id: 9135:TNFAIP6
uniprot id: A0A8C9N046
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:PNPLA4
gene id: 9135:PNPLA4
uniprot id: A0A8C9NIG5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:GMPPB
gene id: 9135:GMPPB
uniprot id: A0A8C9NK98
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

9135:BCL2L1
gene id: 9135:BCL2L1
uniprot id: A0A8C9NN65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane
messages: Mitochondrion matrix
messages: Nucleus membrane
messages: centrosome
messages: cytosol
messages: synaptic vesicle membrane

9135:TUSC3
gene id: 9135:TUSC3
uniprot id: A0A8C9UCQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9135:TIMM10
gene id: 9135:TIMM10
uniprot id: A0A8C9N6X1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

9135:LRRFIP2
gene id: 9135:LRRFIP2
uniprot id: A0A8C9NX34
uniprot id: A0A8C9NXE6
names: Similarity
messages: Belongs to the LRRFIP family.

9135:PDE6H
gene id: 9135:PDE6H
uniprot id: A0A8C9MTG5
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

9135:KATNAL1
gene id: 9135:KATNAL1
uniprot id: A0A8C9UBK9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily.
messages: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit.
messages: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
messages: Cytoplasm
messages: Interacts with KATNB1 and KATNBL1.
messages: Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays.
messages: centrosome
messages: cytoskeleton
messages: spindle
messages: spindle pole

9135:MIEF1
gene id: 9135:MIEF1
uniprot id: A0A8C9MQ17
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

9135:LOC103815539
gene id: 9135:LOC103815539
uniprot id: A0A8C9N2A1
uniprot id: A0A8C9N2R1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9135:LOC103826639
gene id: 9135:LOC103826639
uniprot id: A0A8C9NK90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRPH2/ROM1 family.
messages: Membrane

9135:TUBB6
gene id: 9135:TUBB6
uniprot id: A0A8C9N111
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

9135:LOC103824645
gene id: 9135:LOC103824645
uniprot id: A0A8C9UGA3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus

9135:CENPU
gene id: 9135:CENPU
uniprot id: A0A8C9N701
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-U/AME1 family.
messages: Nucleus

9135:SLC17A6
gene id: 9135:SLC17A6
uniprot id: A0A8C9N288
names: Subcellular Location Annotation
messages: Membrane

9135:B3GNT5
gene id: 9135:B3GNT5
uniprot id: A0A8C9NL43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9135:POFUT1
gene id: 9135:POFUT1
uniprot id: A0A8C9NKP0
names: Similarity
messages: Belongs to the glycosyltransferase 65 family.

9135:DKK2
gene id: 9135:DKK2
uniprot id: A0A8C9NJR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

9135:CLTCL1
gene id: 9135:CLTCL1
uniprot id: A0A8C9MM72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin heavy chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: coated pit

9135:RGS7BP
gene id: 9135:RGS7BP
uniprot id: A0A8C9N9X9
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

9135:NSF
gene id: 9135:NSF
uniprot id: A0A8C9N0L9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.

9135:TMEM59
gene id: 9135:TMEM59
uniprot id: A0A8C9U9N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM59 family.
messages: Golgi apparatus membrane
messages: Membrane

9135:BID
gene id: 9135:BID
uniprot id: A0A8C9MRC5
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Forms heterodimers either with the pro-apoptotic protein BAX or the anti-apoptotic protein BCL2.
messages: Induces caspases and apoptosis. Counters the protective effect of BCL2.
messages: Intact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family.
messages: Membrane
messages: Mitochondrion outer membrane

9135:NPL
gene id: 9135:NPL
uniprot id: A0A8C9N927
names: Similarity
names: Subunit
messages: Belongs to the DapA family.
messages: Homotetramer.

9135:MPI
gene id: 9135:MPI
uniprot id: A0A8C9NEC0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

9135:TSPAN33
gene id: 9135:TSPAN33
uniprot id: A0A8C9MYI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9135:ARPC1B
gene id: 9135:ARPC1B
uniprot id: A0A8C9N2G8
names: Function
names: Similarity
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.

9135:SLC17A8
gene id: 9135:SLC17A8
uniprot id: A0A8C9MUH3
names: Subcellular Location Annotation
messages: Membrane

9135:EMC1
gene id: 9135:EMC1
uniprot id: A0A8C9KWI6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC1 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

9135:PAH
gene id: 9135:PAH
uniprot id: A0A8C9UE43
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

9135:MAB21L2
gene id: 9135:MAB21L2
uniprot id: A0A8C9UGZ5
names: Similarity
messages: Belongs to the mab-21 family.

9135:FABP3
gene id: 9135:FABP3
uniprot id: A0A8C9NPY3
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

9135:SLC29A1
gene id: 9135:SLC29A1
uniprot id: A0A8C9NLH3
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Lateral cell membrane
messages: Membrane

9135:QNG1
gene id: 9135:QNG1
uniprot id: A0A8C9MN88
names: Function
names: Similarity
messages: Belongs to the QNG1 protein family.
messages: Catalyzes the hydrolysis of queuosine 5'-phosphate, releasing the nucleobase queuine (q). Is required for salvage of queuine from exogenous queuosine (Q) that is imported and then converted to queuosine 5'-phosphate intracellularly.

9135:SAG
gene id: 9135:SAG
uniprot id: A0A8C9MIF4
names: Similarity
messages: Belongs to the arrestin family.

9135:BORCS5
gene id: 9135:BORCS5
uniprot id: A0A8C9N962
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS5 family.
messages: Lysosome membrane
messages: Membrane

9135:UNC119
gene id: 9135:UNC119
uniprot id: A0A8C9MXB8
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

9135:EPS8
gene id: 9135:EPS8
uniprot id: A0A8C9MV61
names: Similarity
messages: Belongs to the EPS8 family.

9135:TCEANC2
gene id: 9135:TCEANC2
uniprot id: A0A8C9MTY4
names: Subcellular Location Annotation
messages: Nucleus

9135:LOC103817059
gene id: 9135:LOC103817059
uniprot id: A0A8C9UAI5
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:VWA2
gene id: 9135:VWA2
uniprot id: A0A8C9UHN6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:TNFRSF6B
gene id: 9135:TNFRSF6B
uniprot id: A0A8C9NP97
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:TMEM38A
gene id: 9135:TMEM38A
uniprot id: A0A8C9U756
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

9135:RFC4
gene id: 9135:RFC4
uniprot id: A0A8C9UFZ0
names: Similarity
messages: Belongs to the activator 1 small subunits family.

9135:XG
gene id: 9135:XG
uniprot id: A0A8C9NUS0
names: Similarity
messages: Belongs to the CD99 family.

9135:LIPC
gene id: 9135:LIPC
uniprot id: A0A8C9KU62
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9135:CCR7
gene id: 9135:CCR7
uniprot id: A0A8C9UBS0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9135:LOC103826647
gene id: 9135:LOC103826647
uniprot id: A0A8C9KRK7
uniprot id: A0A8C9KVC0
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

9135:FLOT1
gene id: 9135:FLOT1
uniprot id: A0A8C9NSX4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Endosome
messages: Heterooligomeric complex.
messages: Membrane

9135:POMT1
gene id: 9135:POMT1
uniprot id: A0A8C9MLL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

9135:LOC103813361
gene id: 9135:LOC103813361
uniprot id: A0A8C9MVI7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9135:SLC35D2
gene id: 9135:SLC35D2
uniprot id: A0A8C9MJ64
names: Subcellular Location Annotation
messages: Membrane

9135:HHIP
gene id: 9135:HHIP
uniprot id: A0A8C9NLS8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:HTT
gene id: 9135:HTT
uniprot id: A0A8C9NSR2
uniprot id: A0A8C9UH73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the huntingtin family.
messages: Cytoplasm
messages: May play a role in microtubule-mediated transport or vesicle function.
messages: Nucleus

9135:ATP8B1
gene id: 9135:ATP8B1
uniprot id: A0A8C9MJE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

9135:LOC103820837
gene id: 9135:LOC103820837
uniprot id: A0A8C9MHF6
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

9135:DDB2
gene id: 9135:DDB2
uniprot id: A0A8C9U5N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: Nucleus

9135:EIF5
gene id: 9135:EIF5
uniprot id: A0A8C9UBH5
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

9135:DCTN4
gene id: 9135:DCTN4
uniprot id: A0A8C9NCH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunit 4 family.
messages: cell cortex
messages: centrosome
messages: sarcomere
messages: stress fiber

9135:FAM8A1
gene id: 9135:FAM8A1
uniprot id: A0A8C9KW79
names: Subcellular Location Annotation
messages: Membrane

9135:LOC103813978
gene id: 9135:LOC103813978
uniprot id: A0A8C9KQI3
names: Similarity
messages: Belongs to the cytochrome P450 family.

9135:DAO
gene id: 9135:DAO
uniprot id: A0A8C9MWA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

9135:TNFRSF19
gene id: 9135:TNFRSF19
uniprot id: A0A8C9MQ04
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:LYPLA1
gene id: 9135:LYPLA1
uniprot id: A0A8C9NFX2
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

9135:PDZK1IP1
gene id: 9135:PDZK1IP1
uniprot id: A0A8C9MJC8
names: Subcellular Location Annotation
messages: Membrane

9135:GET4
gene id: 9135:GET4
uniprot id: A0A8C9UDR0
names: Similarity
messages: Belongs to the GET4 family.

9135:DTNBP1
gene id: 9135:DTNBP1
uniprot id: A0A8C9L117
names: Similarity
messages: Belongs to the dysbindin family.

9135:C1H11orf87
gene id: 9135:C1H11orf87
uniprot id: A0A8C9MNF0
names: Subcellular Location Annotation
messages: Membrane

9135:OXR1
gene id: 9135:OXR1
uniprot id: A0A8C9MSG8
names: Similarity
messages: Belongs to the OXR1 family.

9135:TMCO3
gene id: 9135:TMCO3
uniprot id: A0A8C9MMA9
names: Subcellular Location Annotation
messages: Membrane

9135:MZT1
gene id: 9135:MZT1
uniprot id: A0A8C9NQ72
names: Function
names: Similarity
messages: Belongs to the MOZART1 family.
messages: Required for gamma-tubulin complex recruitment to the centrosome.

9135:CALHM4
gene id: 9135:CALHM4
uniprot id: A0A8C9NMQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

9135:IL1RAP
gene id: 9135:IL1RAP
uniprot id: A0A8C9NQJ6
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

9135:TCFL5
gene id: 9135:TCFL5
uniprot id: A0A8C9NNV9
names: Subcellular Location Annotation
messages: Nucleus

9135:RNF168
gene id: 9135:RNF168
uniprot id: A0A8C9MYD2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNF168 family.
messages: Nucleus
messages: The MIU motif (motif interacting with ubiquitin) mediates the interaction with both 'Lys-48'- and 'Lys-63'-linked ubiquitin chains. The UMI motif mediates interaction with ubiquitin with a preference for 'Lys-63'-linked ubiquitin. The specificity for different types of ubiquitin is mediated by juxtaposition of ubiquitin-binding motifs (MIU and UMI motifs) with LR motifs (LRMs).

9135:ACER3
gene id: 9135:ACER3
uniprot id: A0A8C9KV30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Membrane

9135:CCDC65
gene id: 9135:CCDC65
uniprot id: A0A8C9UGL8
names: Subcellular Location Annotation
messages: flagellum axoneme

9135:MTHFD1
gene id: 9135:MTHFD1
uniprot id: A0A8C9MTN1
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

9135:PEX2
gene id: 9135:PEX2
uniprot id: A0A8C9MFL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pex2/pex10/pex12 family.
messages: Membrane
messages: Peroxisome membrane

9135:TNMD
gene id: 9135:TNMD
uniprot id: A0A8C9MJ63
names: Similarity
messages: Belongs to the chondromodulin-1 family.

9135:TPRKB
gene id: 9135:TPRKB
uniprot id: A0A8C9MP26
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

9135:FUBP1
gene id: 9135:FUBP1
uniprot id: A0A8C9NML0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9135:NR2E3
gene id: 9135:NR2E3
uniprot id: A0A8C9UHH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9135:HNRNPH1
gene id: 9135:HNRNPH1
uniprot id: A0A8C9NA30
names: Subcellular Location Annotation
messages: nucleoplasm

9135:F9
gene id: 9135:F9
uniprot id: A0A8C9MJA4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9135:HOXD11
gene id: 9135:HOXD11
uniprot id: A0A8C9NMT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

9135:ARRB1
gene id: 9135:ARRB1
uniprot id: A0A8C9NWA1
names: Similarity
messages: Belongs to the arrestin family.

9135:ATP10B
gene id: 9135:ATP10B
uniprot id: A0A8C9N9T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

9135:OPN3
gene id: 9135:OPN3
uniprot id: A0A8C9N177
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9135:HDLBP
gene id: 9135:HDLBP
uniprot id: A0A8C9MX26
names: Subcellular Location Annotation
messages: Cytoplasm

9135:LOC103821188
gene id: 9135:LOC103821188
uniprot id: A0A8C9UGC7
names: Similarity
messages: Belongs to the cytochrome P450 family.

9135:SENP8
gene id: 9135:SENP8
uniprot id: A0A8C9NSU1
names: Similarity
messages: Belongs to the peptidase C48 family.

9135:MCM10
gene id: 9135:MCM10
uniprot id: A0A8C9N2S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM10 family.
messages: Nucleus

9135:LOC103816636
gene id: 9135:LOC103816636
uniprot id: A0A8C9U7Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

9135:SSH1
gene id: 9135:SSH1
uniprot id: A0A8C9MWX8
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

9135:FKTN
gene id: 9135:FKTN
uniprot id: A0A8C9NP02
names: Similarity
messages: Belongs to the LicD transferase family.

9135:RNF157
gene id: 9135:RNF157
uniprot id: A0A8C9MHQ1
uniprot id: A0A8C9MHS2
uniprot id: A0A8C9MHT8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin ligase.

9135:AVL9
gene id: 9135:AVL9
uniprot id: A0A8C9MFX4
names: Subcellular Location Annotation
messages: Recycling endosome

9135:CD82
gene id: 9135:CD82
uniprot id: A0A8C9MJH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9135:DNAJC24
gene id: 9135:DNAJC24
uniprot id: A0A8C9MZ72
names: Similarity
messages: Belongs to the DPH4 family.

9135:CSF1R
gene id: 9135:CSF1R
uniprot id: A0A8C9NEQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

9135:LOC103819550
gene id: 9135:LOC103819550
uniprot id: A0A8C9MVA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acyl-CoA reductase family.
messages: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
messages: Peroxisome membrane

9135:LOC103823511
gene id: 9135:LOC103823511
uniprot id: A0A8C9MWT2
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

9135:LOC103812638
gene id: 9135:LOC103812638
uniprot id: A0A8C9L4K8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9135:SERPINB1
gene id: 9135:SERPINB1
uniprot id: A0A8C9L451
names: Similarity
messages: Belongs to the serpin family.

9135:LOC103823992
gene id: 9135:LOC103823992
uniprot id: A0A8C9UE50
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

9135:FABP2
gene id: 9135:FABP2
uniprot id: A0A8C9KZD8
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

9135:TGM4
gene id: 9135:TGM4
uniprot id: A0A8C9KVA3
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

9135:ATG3
gene id: 9135:ATG3
uniprot id: A0A8C9N5C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG3 family.
messages: Cytoplasm

9135:CRMP1
gene id: 9135:CRMP1
uniprot id: A0A8C9KNW8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

9135:TXNRD2
gene id: 9135:TXNRD2
uniprot id: A0A8C9U8L9
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

9135:ANTXRL
gene id: 9135:ANTXRL
uniprot id: A0A8C9NXR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

9135:SLC22A3
gene id: 9135:SLC22A3
uniprot id: A0A8C9N8T4
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

9135:AHCY
gene id: 9135:AHCY
uniprot id: A0A8C9N1J7
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

9135:MFSD14A
gene id: 9135:MFSD14A
uniprot id: A0A8C9UF24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

9135:LOC103813632
gene id: 9135:LOC103813632
uniprot id: A0A8C9MUX5
uniprot id: A0A8C9UBK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

9135:SRP14
gene id: 9135:SRP14
uniprot id: A0A8C9NCW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP14 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm
messages: Heterodimer with SRP9; binds RNA as heterodimer. Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.

9135:NOL12
gene id: 9135:NOL12
uniprot id: A0A8C9MM17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP17 family.
messages: nucleolus

9135:LPIN2
gene id: 9135:LPIN2
uniprot id: A0A8C9N5F4
names: Similarity
messages: Belongs to the lipin family.

9135:MB
gene id: 9135:MB
uniprot id: A0A8C9MKI6
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

9135:TDP1
gene id: 9135:TDP1
uniprot id: A0A8C9N2A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosyl-DNA phosphodiesterase family.
messages: Nucleus

9135:MRTO4
gene id: 9135:MRTO4
uniprot id: A0A8C9KXX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the pre-60S ribosomal particle.
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
messages: Cytoplasm
messages: nucleolus

9135:SYNJ2
gene id: 9135:SYNJ2
uniprot id: A0A8C9NKB7
names: Similarity
messages: Belongs to the synaptojanin family.
messages: In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.

9135:CXCL12
gene id: 9135:CXCL12
uniprot id: A0A8C9NXK5
names: Similarity
messages: Belongs to the intercrine alpha (chemokine CxC) family.

9135:RAX2
gene id: 9135:RAX2
uniprot id: A0A8C9L239
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

9135:LCK
gene id: 9135:LCK
uniprot id: A0A8C9MNF4
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

9135:LOC103813390
gene id: 9135:LOC103813390
uniprot id: A0A8C9MGZ1
names: Subcellular Location Annotation
messages: Membrane

9135:FAM83H
gene id: 9135:FAM83H
uniprot id: A0A8C9L216
names: Similarity
messages: Belongs to the FAM83 family.

9135:XRCC5
gene id: 9135:XRCC5
uniprot id: A0A8C9NF07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ku80 family.
messages: Nucleus
messages: Single-stranded DNA-dependent ATP-dependent helicase.

9135:ORC4
gene id: 9135:ORC4
uniprot id: A0A8C9MYK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC4 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication.
messages: Nucleus

9135:ASF1A
gene id: 9135:ASF1A
uniprot id: A0A8C9NLA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

9135:ADHFE1
gene id: 9135:ADHFE1
uniprot id: A0A8C9NFY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
messages: Mitochondrion

9135:FMO1
gene id: 9135:FMO1
uniprot id: A0A8C9MFV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9135:BMP10
gene id: 9135:BMP10
uniprot id: A0A8C9UHR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

9135:ALDH8A1
gene id: 9135:ALDH8A1
uniprot id: A0A8C9N763
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

9135:UBN2
gene id: 9135:UBN2
uniprot id: A0A8C9MT05
names: Similarity
messages: Belongs to the ubinuclein family.

9135:TMCO4
gene id: 9135:TMCO4
uniprot id: A0A8C9MED7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMCO4 family.
messages: Membrane

9135:LOC103813317
gene id: 9135:LOC103813317
uniprot id: A0A8C9UAN3
names: Similarity
messages: Belongs to the globin family.

9135:LOC103822502
gene id: 9135:LOC103822502
uniprot id: A0A8C9NGL8
names: Similarity
messages: Belongs to the peptidase M14 family.

9135:GRK5
gene id: 9135:GRK5
uniprot id: A0A8C9NM30
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

9135:FAS
gene id: 9135:FAS
uniprot id: A0A8C9NYC9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

9135:FZR1
gene id: 9135:FZR1
uniprot id: A0A8C9KWN3
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

9135:ADIPOR2
gene id: 9135:ADIPOR2
uniprot id: A0A8C9U9B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

9135:ODC1
gene id: 9135:ODC1
uniprot id: A0A8C9NGX2
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

9135:SCTR
gene id: 9135:SCTR
uniprot id: A0A8C9NAV7
names: Subcellular Location Annotation
messages: Membrane

9135:LOC103814920
gene id: 9135:LOC103814920
uniprot id: A0A8C9NJ59
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:LOC103822488
gene id: 9135:LOC103822488
uniprot id: A0A8C9MMT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus

9135:ADA2
gene id: 9135:ADA2
uniprot id: A0A8C9MT08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. ADGF subfamily.
messages: Secreted

9135:CPSF4
gene id: 9135:CPSF4
uniprot id: A0A8C9UD63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex.
messages: Nucleus

9135:SERINC3
gene id: 9135:SERINC3
uniprot id: A0A8C9NEZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

9135:NRP1
gene id: 9135:NRP1
uniprot id: A0A8C9MZC4
names: Caution
names: Similarity
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:SLC37A1
gene id: 9135:SLC37A1
uniprot id: A0A8C9N9Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

9135:TBX20
gene id: 9135:TBX20
uniprot id: A0A8C9UDN0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9135:GDF2
gene id: 9135:GDF2
uniprot id: A0A8C9NVZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

9135:MSRA
gene id: 9135:MSRA
uniprot id: A0A8C9UGK9
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.

9135:B3GNT9
gene id: 9135:B3GNT9
uniprot id: A0A8C9MQ14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9135:LOC103816830
gene id: 9135:LOC103816830
uniprot id: A0A8C9MQ55
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9135:TBC1D7
gene id: 9135:TBC1D7
uniprot id: A0A8C9KR12
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Vesicle

9135:FOXP1
gene id: 9135:FOXP1
uniprot id: A0A8C9N189
uniprot id: A0A8C9UCK5
names: Subcellular Location Annotation
messages: Nucleus

9135:PLRG1
gene id: 9135:PLRG1
uniprot id: A0A8C9NDM1
names: Similarity
messages: Belongs to the WD repeat PRL1/PRL2 family.

9135:TMEM170B
gene id: 9135:TMEM170B
uniprot id: A0A8C9KX27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM170 family.
messages: Membrane

9135:NIPA2
gene id: 9135:NIPA2
uniprot id: A0A8C9NSR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

9135:PSMG2
gene id: 9135:PSMG2
uniprot id: A0A8C9UCH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PSMG2 family.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1.
messages: Forms a heterodimer with PSMG1.

9135:SURF6
gene id: 9135:SURF6
uniprot id: A0A8C9MK82
names: Similarity
messages: Belongs to the SURF6 family.

9135:BCL9L
gene id: 9135:BCL9L
uniprot id: A0A8C9NW19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCL9 family.
messages: Nucleus

9135:MINDY4
gene id: 9135:MINDY4
uniprot id: A0A8C9MUG7
uniprot id: A0A8C9UA16
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
messages: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

9135:TNFRSF21
gene id: 9135:TNFRSF21
uniprot id: A0A8C9UG77
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:STEEP1
gene id: 9135:STEEP1
uniprot id: A0A8C9NX58
names: Similarity
messages: Belongs to the STEEP1 family.

9135:DPYSL2
gene id: 9135:DPYSL2
uniprot id: A0A8C9NYJ4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

9135:RGS9BP
gene id: 9135:RGS9BP
uniprot id: A0A8C9U7A7
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

9135:SLC26A2
gene id: 9135:SLC26A2
uniprot id: A0A8C9KYT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane
messages: Sulfate transporter which mediates sulfate uptake into chondrocytes in order to maintain adequate sulfation of proteoglycans which is needed for cartilage development. Mediates electroneutral anion exchange of sulfate ions for oxalate ions, sulfate and oxalate ions for chloride and/or hydroxyl ions and chloride ions for bromide, iodide and nitrate ions. The coupling of sulfate transport to both hydroxyl and chloride ions likely serves to ensure transport at both acidic pH when most sulfate uptake is mediated by sulfate-hydroxide exchange and alkaline pH when most sulfate uptake is mediated by sulfate-chloride exchange. Essential for chondrocyte proliferation, differentiation and cell size expansion.

9135:CXCR4
gene id: 9135:CXCR4
uniprot id: A0A8C9N910
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Late endosome
messages: Lysosome
messages: Membrane

9135:GRPR
gene id: 9135:GRPR
uniprot id: A0A8C9NLB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9135:RRM2
gene id: 9135:RRM2
uniprot id: A0A8C9NFW0
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

9135:KCTD10
gene id: 9135:KCTD10
uniprot id: A0A8C9MUW3
uniprot id: A0A8C9U9W3
names: Similarity
messages: Belongs to the BACURD family.

9135:SGTB
gene id: 9135:SGTB
uniprot id: A0A8C9UEZ5
names: Similarity
messages: Belongs to the SGT family.

9135:FH
gene id: 9135:FH
uniprot id: A0A8C9MSA0
names: Function
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Catalyzes the hydration of fumarate to L-malate in the tricarboxylic acid (TCA) cycle to facilitate a transition step in the production of energy in the form of NADH.

9135:S100Z
gene id: 9135:S100Z
uniprot id: A0A8C9MQ28
names: Similarity
messages: Belongs to the S-100 family.

9135:LOC103818639
gene id: 9135:LOC103818639
uniprot id: A0A8C9NIP8
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

9135:NDUFS8
gene id: 9135:NDUFS8
uniprot id: A0A8C9NCY5
names: Similarity
messages: Belongs to the complex I 23 kDa subunit family.

9135:E2F8
gene id: 9135:E2F8
uniprot id: A0A8C9N6I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

9135:AURKAIP1
gene id: 9135:AURKAIP1
uniprot id: A0A8C9NVV3
names: Similarity
messages: Belongs to the mitochondrion-specific ribosomal protein mS38 family.

9135:TMCC3
gene id: 9135:TMCC3
uniprot id: A0A8C9UBA9
names: Similarity
messages: Belongs to the TEX28 family.

9135:MID1
gene id: 9135:MID1
uniprot id: A0A8C9NHT8
names: Subcellular Location Annotation
messages: cytoskeleton

9135:ELF1
gene id: 9135:ELF1
uniprot id: A0A8C9NMU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9135:MFNG
gene id: 9135:MFNG
uniprot id: A0A8C9ML66
names: Subcellular Location Annotation
messages: Membrane

9135:SBNO2
gene id: 9135:SBNO2
uniprot id: A0A8C9MTS6
uniprot id: A0A8C9U9X7
names: Similarity
messages: Belongs to the SBNO family.

9135:GLE1
gene id: 9135:GLE1
uniprot id: A0A8C9MU16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLE1 family.
messages: Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC).
messages: nuclear pore complex

9135:SERPINA10
gene id: 9135:SERPINA10
uniprot id: A0A8C9MZ18
names: Similarity
messages: Belongs to the serpin family.

9135:TPST1
gene id: 9135:TPST1
uniprot id: A0A8C9UBR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein sulfotransferase family.
messages: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
messages: Golgi apparatus membrane

9135:SNRPD3
gene id: 9135:SNRPD3
uniprot id: A0A8C9MJF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

9135:MLLT1
gene id: 9135:MLLT1
uniprot id: A0A8C9MGK0
names: Subcellular Location Annotation
messages: Nucleus

9135:PTHLH
gene id: 9135:PTHLH
uniprot id: A0A8C9N609
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: Secreted

9135:LOC103825306
gene id: 9135:LOC103825306
uniprot id: A0A8C9L5U5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Secreted

9135:JAGN1
gene id: 9135:JAGN1
uniprot id: A0A8C9MR69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the jagunal family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9135:GJD4
gene id: 9135:GJD4
uniprot id: A0A8C9MZY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9135:PIGP
gene id: 9135:PIGP
uniprot id: A0A8C9UDZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGP family.
messages: Membrane
messages: Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

9135:UGT8
gene id: 9135:UGT8
uniprot id: A0A8C9N5D3
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

9135:PPP4R3B
gene id: 9135:PPP4R3B
uniprot id: A0A8C9NML7
names: Similarity
messages: Belongs to the SMEK family.

9135:PYCR3
gene id: 9135:PYCR3
uniprot id: A0A8C9KNN1
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

9135:DSE
gene id: 9135:DSE
uniprot id: A0A8C9NNU8
names: Similarity
messages: Belongs to the dermatan-sulfate isomerase family.

9135:BTK
gene id: 9135:BTK
uniprot id: A0A8C9NXU9
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

9135:LOC103820244
gene id: 9135:LOC103820244
uniprot id: A0A8C9MNU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

9135:PLIN2
gene id: 9135:PLIN2
uniprot id: A0A8C9KX54
names: Similarity
messages: Belongs to the perilipin family.

9135:ATP5F1E
gene id: 9135:ATP5F1E
uniprot id: A0A8C9NPU6
names: Function
names: Similarity
messages: Belongs to the eukaryotic ATPase epsilon family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

9135:SLC18B1
gene id: 9135:SLC18B1
uniprot id: A0A8C9NBT9
names: Subcellular Location Annotation
messages: Membrane

9135:IL4R
gene id: 9135:IL4R
uniprot id: A0A8C9MHP8
names: Function
names: Similarity
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.

9135:RNF146
gene id: 9135:RNF146
uniprot id: A0A8C9NN41
names: Domain
names: Function
names: PTM
names: Subcellular Location Annotation
messages: E3 ubiquitin-protein ligase that specifically binds poly-ADP-ribosylated proteins and mediates their ubiquitination and subsequent degradation.
messages: The WWE domain mediates non-covalent poly(ADP-ribose)-binding.
messages: Ubiquitinated; autoubiquitinated.
messages: cytosol

9135:ADA
gene id: 9135:ADA
uniprot id: A0A8C9NGL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
messages: Cell junction
messages: Cell membrane
messages: Cytoplasmic vesicle lumen

9135:LOC103817025
gene id: 9135:LOC103817025
uniprot id: A0A8C9N4N9
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

9135:SERPINB5
gene id: 9135:SERPINB5
uniprot id: A0A8C9MG24
names: Similarity
messages: Belongs to the serpin family. Ov-serpin subfamily.

9135:BASP1
gene id: 9135:BASP1
uniprot id: A0A8C9MLK0
names: Similarity
messages: Belongs to the BASP1 family.

9135:MELTF
gene id: 9135:MELTF
uniprot id: A0A8C9NS58
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferrin family.
messages: Monomer.
messages: Secreted

9135:NFIB
gene id: 9135:NFIB
uniprot id: A0A8C9KX81
uniprot id: A0A8C9KZM2
uniprot id: A0A8C9MEJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

9135:NEIL2
gene id: 9135:NEIL2
uniprot id: A0A8C9UGI9
names: Similarity
messages: Belongs to the FPG family.

9135:AKR1A1
gene id: 9135:AKR1A1
uniprot id: A0A8C9KWQ1
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the aldo/keto reductase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

9135:DDX41
gene id: 9135:DDX41
uniprot id: A0A8C9NKR1
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX41 subfamily.

9135:ORAI2
gene id: 9135:ORAI2
uniprot id: A0A8C9U9D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

9135:LOC103827204
gene id: 9135:LOC103827204
uniprot id: A0A8C9NFR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transthyretin family.
messages: Homotetramer.
messages: Secreted
messages: Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.

9135:ADRA1A
gene id: 9135:ADRA1A
uniprot id: A0A8C9NYC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Nucleus membrane
messages: caveola

9135:PPP1R21
gene id: 9135:PPP1R21
uniprot id: A0A8C9NDB2
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

9135:LOC103825436
gene id: 9135:LOC103825436
uniprot id: A0A8C9KYB6
names: Subcellular Location Annotation
messages: Mitochondrion

9135:CEP170B
gene id: 9135:CEP170B
uniprot id: A0A8C9MV07
uniprot id: A0A8C9MV21
uniprot id: A0A8C9U9Y7
names: Similarity
messages: Belongs to the CEP170 family.

9135:SMC4
gene id: 9135:SMC4
uniprot id: A0A8C9N2L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family.
messages: Chromosome
messages: Nucleus

9135:LOC103812446
gene id: 9135:LOC103812446
uniprot id: A0A8C9NGB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

9135:KIF21A
gene id: 9135:KIF21A
uniprot id: A0A8C9MPC0
uniprot id: A0A8C9U7N1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9135:DCBLD1
gene id: 9135:DCBLD1
uniprot id: A0A8C9NIF9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:LPAR5
gene id: 9135:LPAR5
uniprot id: A0A8C9NEH0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9135:GALM
gene id: 9135:GALM
uniprot id: A0A8C9KTT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldose epimerase family.
messages: Monomer.
messages: Mutarotase that catalyzes the interconversion of beta-D-galactose and alpha-D-galactose during galactose metabolism.

9135:EZR
gene id: 9135:EZR
uniprot id: A0A8C9NLK8
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

9135:ADI1
gene id: 9135:ADI1
uniprot id: A0A8C9UEV4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.
messages: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

9135:LOC103815785
gene id: 9135:LOC103815785
uniprot id: A0A8C9NCR2
names: Subcellular Location Annotation
messages: Membrane

9135:TRMT2A
gene id: 9135:TRMT2A
uniprot id: A0A8C9MN38
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:PHKG1
gene id: 9135:PHKG1
uniprot id: A0A8C9MW19
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily.
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.

9135:TLX1
gene id: 9135:TLX1
uniprot id: A0A8C9NW32
names: Subcellular Location Annotation
messages: Nucleus

9135:POLR2C
gene id: 9135:POLR2C
uniprot id: A0A8C9UB45
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

9135:GAR1
gene id: 9135:GAR1
uniprot id: A0A8C9UFZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GAR1 family.
messages: Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).
messages: Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.
messages: nucleolus

9135:PPP2R5C
gene id: 9135:PPP2R5C
uniprot id: A0A8C9MX11
uniprot id: A0A8C9UBZ9
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

9135:CASP6
gene id: 9135:CASP6
uniprot id: A0A8C9NDD1
names: Similarity
messages: Belongs to the peptidase C14A family.

9135:SLC7A3
gene id: 9135:SLC7A3
uniprot id: A0A8C9UIP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

9135:AQP4
gene id: 9135:AQP4
uniprot id: A0A8C9UEZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

9135:UBR2
gene id: 9135:UBR2
uniprot id: A0A8C9N305
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

9135:SMU1
gene id: 9135:SMU1
uniprot id: A0A8C9NB30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SMU1 family.
messages: Nucleus speckle

9135:PHACTR2
gene id: 9135:PHACTR2
uniprot id: A0A8C9NM90
uniprot id: A0A8C9NNN5
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

9135:GTF2H5
gene id: 9135:GTF2H5
uniprot id: A0A8C9NJK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB5 family.
messages: Component of the 7-subunit TFIIH core complex.
messages: In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.
messages: Nucleus

9135:USP22
gene id: 9135:USP22
uniprot id: A0A8C9N4D9
names: Similarity
messages: Belongs to the peptidase C19 family.

9135:RNF135
gene id: 9135:RNF135
uniprot id: A0A8C9NJ14
names: Subcellular Location Annotation
messages: Cytoplasm

9135:GTPBP10
gene id: 9135:GTPBP10
uniprot id: A0A8C9NE42
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

9135:FAXC
gene id: 9135:FAXC
uniprot id: A0A8C9L2I7
names: Similarity
messages: Belongs to the FAX family.

9135:TUBD1
gene id: 9135:TUBD1
uniprot id: A0A8C9N8W6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Nucleus
messages: centriole
messages: cilium

9135:PPIL1
gene id: 9135:PPIL1
uniprot id: A0A8C9MVA8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

9135:SVOP
gene id: 9135:SVOP
uniprot id: A0A8C9MXR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

9135:LOC103816031
gene id: 9135:LOC103816031
uniprot id: A0A8C9MP90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Membrane
messages: cytoskeleton

9135:NAA60
gene id: 9135:NAA60
uniprot id: A0A8C9ND90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA60 subfamily.
messages: Golgi apparatus membrane

9135:SUPT4H1
gene id: 9135:SUPT4H1
uniprot id: A0A8C9MLZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT4 family.
messages: Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II.
messages: Nucleus

9135:SMAD5
gene id: 9135:SMAD5
uniprot id: A0A8C9NC62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

9135:SLC6A4
gene id: 9135:SLC6A4
uniprot id: A0A8C9N4I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A4 subfamily.
messages: Cell membrane
messages: Endomembrane system
messages: Endosome membrane
messages: Membrane
messages: Synapse
messages: focal adhesion
messages: neuron projection

9135:PSKH1
gene id: 9135:PSKH1
uniprot id: A0A8C9MTT4
names: Similarity
messages: Belongs to the protein kinase superfamily.

9135:CPLX3
gene id: 9135:CPLX3
uniprot id: A0A8C9NGN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

9135:RPS21
gene id: 9135:RPS21
uniprot id: A0A8C9NN54
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS21 family.
messages: Component of the 40S small ribosomal subunit.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum
messages: cytosol

9135:RPLP2
gene id: 9135:RPLP2
uniprot id: A0A8C9NP01
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

9135:CTBP2
gene id: 9135:CTBP2
uniprot id: A0A8C9NET7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

9135:LOC103827193
gene id: 9135:LOC103827193
uniprot id: A0A8C9NBU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transthyretin family.
messages: Homotetramer.
messages: Secreted
messages: Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.

9135:INTS13
gene id: 9135:INTS13
uniprot id: A0A8C9N4V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the asunder family.
messages: Cytoplasm
messages: Nucleus

9135:AFG3L2
gene id: 9135:AFG3L2
uniprot id: A0A8C9MZT0
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

9135:RIPOR2
gene id: 9135:RIPOR2
uniprot id: A0A8C9MVR8
uniprot id: A0A8C9MYB6
names: Similarity
messages: Belongs to the RIPOR family.

9135:CHGB
gene id: 9135:CHGB
uniprot id: A0A8C9KTQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

9135:DENND6A
gene id: 9135:DENND6A
uniprot id: A0A8C9MKV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND6 family.
messages: Recycling endosome

9135:SNX5
gene id: 9135:SNX5
uniprot id: A0A8C9NCD9
names: Function
names: Similarity
messages: Belongs to the sorting nexin family.
messages: Involved in several stages of intracellular trafficking.

9135:TENT5C
gene id: 9135:TENT5C
uniprot id: A0A8C9ND96
names: Similarity
messages: Belongs to the TENT family.

9135:FERMT2
gene id: 9135:FERMT2
uniprot id: A0A8C9KUX5
uniprot id: A0A8C9KY44
uniprot id: A0A8C9L6P2
names: Similarity
messages: Belongs to the kindlin family.

9135:GALC
gene id: 9135:GALC
uniprot id: A0A8C9N353
names: Similarity
messages: Belongs to the glycosyl hydrolase 59 family.

9135:LOC103826650
gene id: 9135:LOC103826650
uniprot id: A0A8C9KVI7
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

9135:NDUFV3
gene id: 9135:NDUFV3
uniprot id: A0A8C9NCD2
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. May be the terminally assembled subunit of Complex I.
messages: Belongs to the complex I NDUFV3 subunit family.
messages: Complex I is composed of 45 different subunits. This is a component of the flavoprotein-sulfur (FP) fragment of the enzyme.

9135:HOXD4
gene id: 9135:HOXD4
uniprot id: A0A8C9UHL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

9135:SLC16A8
gene id: 9135:SLC16A8
uniprot id: A0A8C9MM77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

9135:LOC103812363
gene id: 9135:LOC103812363
uniprot id: A0A8C9MHB9
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

9135:LOC103827264
gene id: 9135:LOC103827264
uniprot id: A0A8C9MJL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

9135:COQ10B
gene id: 9135:COQ10B
uniprot id: A0A8C9MH96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

9135:CCNK
gene id: 9135:CCNK
uniprot id: A0A8C9MVQ9
names: Similarity
messages: Belongs to the cyclin family.

9135:AIF1L
gene id: 9135:AIF1L
uniprot id: A0A8C9U839
names: Subcellular Location Annotation
messages: ruffle membrane

9135:LOC103817479
gene id: 9135:LOC103817479
uniprot id: A0A8C9UEY8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9135:SNAPC3
gene id: 9135:SNAPC3
uniprot id: A0A8C9L365
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNAPC3/SRD2 family.
messages: Nucleus
messages: Part of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC3 interacts with SNAPC1.
messages: Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.

9135:FAM167A
gene id: 9135:FAM167A
uniprot id: A0A8C9NM82
names: Similarity
messages: Belongs to the FAM167 (SEC) family.

9135:NPC1
gene id: 9135:NPC1
uniprot id: A0A8C9UDN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

9135:CTNNB1
gene id: 9135:CTNNB1
uniprot id: A0A8C9KV31
names: Similarity
messages: Belongs to the beta-catenin family.

9135:LMOD3
gene id: 9135:LMOD3
uniprot id: A0A8C9MYV7
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

9135:ZP1
gene id: 9135:ZP1
uniprot id: A0A8C9N5X9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:LOC103826296
gene id: 9135:LOC103826296
uniprot id: A0A8C9KPH2
names: Subcellular Location Annotation
messages: centrosome
messages: perinuclear region

9135:HEBP2
gene id: 9135:HEBP2
uniprot id: A0A8C9N937
names: Similarity
messages: Belongs to the HEBP family.

9135:DDX1
gene id: 9135:DDX1
uniprot id: A0A8C9NIB7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX1 subfamily.
messages: Cytoplasmic granule
messages: RNA helicase.
messages: The helicase domain is involved in the stimulation of RELA transcriptional activity.

9135:LOC103822342
gene id: 9135:LOC103822342
uniprot id: A0A8C9NKB9
names: Similarity
messages: Belongs to the peptidase A1 family.

9135:CPB2
gene id: 9135:CPB2
uniprot id: A0A8C9NGH0
uniprot id: A0A8C9NHZ4
names: Similarity
messages: Belongs to the peptidase M14 family.

9135:TIGD5
gene id: 9135:TIGD5
uniprot id: A0A8C9MDL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tigger transposable element derived protein family.
messages: Nucleus

9135:OLA1
gene id: 9135:OLA1
uniprot id: A0A8C9NSE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Cytoplasm
messages: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
messages: Monomer.
messages: Nucleus
messages: nucleolus

9135:CPNE3
gene id: 9135:CPNE3
uniprot id: A0A8C9MGP1
names: Similarity
messages: Belongs to the copine family.

9135:LOC103816800
gene id: 9135:LOC103816800
uniprot id: A0A8C9ML56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the borealin family.
messages: centromere

9135:TTC39A
gene id: 9135:TTC39A
uniprot id: A0A8C9MJQ2
names: Similarity
messages: Belongs to the TTC39 family.

9135:SMARCD3
gene id: 9135:SMARCD3
uniprot id: A0A8C9N7Q5
names: Similarity
messages: Belongs to the SMARCD family.

9135:CYFIP2
gene id: 9135:CYFIP2
uniprot id: A0A8C9NFF1
names: Similarity
messages: Belongs to the CYFIP family.

9135:DCSTAMP
gene id: 9135:DCSTAMP
uniprot id: A0A8C9UAZ4
names: Subcellular Location Annotation
messages: Membrane

9135:PMM1
gene id: 9135:PMM1
uniprot id: A0A8C9MS75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

9135:TMEM150A
gene id: 9135:TMEM150A
uniprot id: A0A8C9NY57
names: Subcellular Location Annotation
messages: Membrane

9135:NSG2
gene id: 9135:NSG2
uniprot id: A0A8C9UGN5
names: Similarity
messages: Belongs to the NSG family.

9135:USP33
gene id: 9135:USP33
uniprot id: A0A8C9NPA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP20/USP33 subfamily.
messages: centrosome
messages: perinuclear region

9135:FTSJ3
gene id: 9135:FTSJ3
uniprot id: A0A8C9UE79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
messages: Interacts with NIP7.
messages: Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation.
messages: nucleolus

9135:CRHBP
gene id: 9135:CRHBP
uniprot id: A0A8C9MP73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRF-binding protein family.
messages: Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy.
messages: Secreted

9135:PRPSAP1
gene id: 9135:PRPSAP1
uniprot id: A0A8C9MHM3
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

9135:NPY1R
gene id: 9135:NPY1R
uniprot id: A0A8C9N749
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9135:LOC103825989
gene id: 9135:LOC103825989
uniprot id: A0A8C9NF53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

9135:SSU72
gene id: 9135:SSU72
uniprot id: A0A8C9UIG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSU72 phosphatase family.
messages: Nucleus
messages: Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination.

9135:GRP
gene id: 9135:GRP
uniprot id: A0A8C9MHL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bombesin/neuromedin-B/ranatensin family.
messages: Secreted

9135:SUMO1
gene id: 9135:SUMO1
uniprot id: A0A8C9MG51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

9135:SLC16A9
gene id: 9135:SLC16A9
uniprot id: A0A8C9MK41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cell membrane
messages: Membrane

9135:LOC103827281
gene id: 9135:LOC103827281
uniprot id: A0A8C9MKV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IAP family.
messages: Cytoplasm
messages: Nucleus

9135:TPM3
gene id: 9135:TPM3
uniprot id: A0A8C9NH29
uniprot id: A0A8C9NHX5
uniprot id: A0A8C9UFH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

9135:SLC35B3
gene id: 9135:SLC35B3
uniprot id: A0A8C9KWJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

9135:MTMR2
gene id: 9135:MTMR2
uniprot id: A0A8C9MKM3
uniprot id: A0A8C9U5D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

9135:LOC103820800
gene id: 9135:LOC103820800
uniprot id: A0A8C9NVZ8
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

9135:GCG
gene id: 9135:GCG
uniprot id: A0A8C9NM54
names: Similarity
messages: Belongs to the glucagon family.

9135:HSPA2
gene id: 9135:HSPA2
uniprot id: A0A8C9U9K3
names: Similarity
messages: Belongs to the heat shock protein 70 family.

9135:PCMTD2
gene id: 9135:PCMTD2
uniprot id: A0A8C9NMG1
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

9135:SEPTIN12
gene id: 9135:SEPTIN12
uniprot id: A0A8C9UFR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cytoplasm

9135:KIF11
gene id: 9135:KIF11
uniprot id: A0A8C9UIN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-5/BimC subfamily.
messages: spindle pole

9135:SGO1
gene id: 9135:SGO1
uniprot id: A0A8C9NPB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

9135:TNFSF13B
gene id: 9135:TNFSF13B
uniprot id: A0A8C9NQU9
names: Similarity
messages: Belongs to the tumor necrosis factor family.

9135:TPST2
gene id: 9135:TPST2
uniprot id: A0A8C9MQJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein sulfotransferase family.
messages: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
messages: Golgi apparatus membrane

9135:PDGFRB
gene id: 9135:PDGFRB
uniprot id: A0A8C9NCM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

9135:SEPTIN5
gene id: 9135:SEPTIN5
uniprot id: A0A8C9MNQ1
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

9135:TFDP1
gene id: 9135:TFDP1
uniprot id: A0A8C9MLW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

9135:HADHB
gene id: 9135:HADHB
uniprot id: A0A8C9NLJ3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

9135:DENND10
gene id: 9135:DENND10
uniprot id: A0A8C9NL94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND10 family.
messages: Endosome
messages: Late endosome

9135:FNIP1
gene id: 9135:FNIP1
uniprot id: A0A8C9N9H2
uniprot id: A0A8C9NBA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNIP family.
messages: Lysosome membrane
messages: Membrane

9135:ABCG5
gene id: 9135:ABCG5
uniprot id: A0A8C9UD36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

9135:DAG1
gene id: 9135:DAG1
uniprot id: A0A8C9UFS7
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.
messages: Transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity.
messages: cytoskeleton
messages: extracellular space
messages: nucleoplasm
messages: sarcolemma

9135:LOC103820320
gene id: 9135:LOC103820320
uniprot id: A0A8C9NA62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

9135:FAM3C
gene id: 9135:FAM3C
uniprot id: A0A8C9KUC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

9135:HAL
gene id: 9135:HAL
uniprot id: A0A8C9MW73
names: Similarity
messages: Belongs to the PAL/histidase family.

9135:LOC103814300
gene id: 9135:LOC103814300
uniprot id: A0A8C9UEM7
names: Similarity
messages: Belongs to the ARTD/PARP family.

9135:LOC103826768
gene id: 9135:LOC103826768
uniprot id: A0A8C9U920
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

9135:GASK1B
gene id: 9135:GASK1B
uniprot id: A0A8C9NB63
names: Similarity
messages: Belongs to the GASK family.

9135:CFI
gene id: 9135:CFI
uniprot id: A0A8C9NHQ4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:LOC103815196
gene id: 9135:LOC103815196
uniprot id: A0A8C9MSY3
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

9135:CHRNG
gene id: 9135:CHRNG
uniprot id: A0A8C9NKU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9135:MED6
gene id: 9135:MED6
uniprot id: A0A8C9NIE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 6 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

9135:IDI1
gene id: 9135:IDI1
uniprot id: A0A8C9UC81
names: Function
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).

9135:ALOX5AP
gene id: 9135:ALOX5AP
uniprot id: A0A8C9MW76
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9135:SFT2D2
gene id: 9135:SFT2D2
uniprot id: A0A8C9UD90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

9135:PSMA1
gene id: 9135:PSMA1
uniprot id: A0A8C9MQE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

9135:DOHH
gene id: 9135:DOHH
uniprot id: A0A8C9MF39
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the deoxyhypusine hydroxylase family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.

9135:MLF1
gene id: 9135:MLF1
uniprot id: A0A8C9N2I3
uniprot id: A0A8C9UDB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLF family.
messages: Cytoplasm

9135:GGT1
gene id: 9135:GGT1
uniprot id: A0A8C9MJU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

9135:CPZ
gene id: 9135:CPZ
uniprot id: A0A8C9NSI7
names: Caution
names: Similarity
messages: Belongs to the peptidase M14 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:CD36
gene id: 9135:CD36
uniprot id: A0A8C9N1M9
names: Similarity
messages: Belongs to the CD36 family.

9135:NPY2R
gene id: 9135:NPY2R
uniprot id: A0A8C9NDG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9135:CCNF
gene id: 9135:CCNF
uniprot id: A0A8C9NG19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family.
messages: Nucleus
messages: centriole
messages: perinuclear region

9135:G6PC1
gene id: 9135:G6PC1
uniprot id: A0A8C9MTW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

9135:SIAH1
gene id: 9135:SIAH1
uniprot id: A0A8C9MMD9
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

9135:CDK3
gene id: 9135:CDK3
uniprot id: A0A8C9MHE7
names: Similarity
messages: Belongs to the protein kinase superfamily.

9135:ROMO1
gene id: 9135:ROMO1
uniprot id: A0A8C9NDU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGR2 family.
messages: Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.
messages: Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation.
messages: Mitochondrion inner membrane

9135:INTS10
gene id: 9135:INTS10
uniprot id: A0A8C9NGI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 10 family.
messages: Nucleus

9135:TUBGCP4
gene id: 9135:TUBGCP4
uniprot id: A0A8C9NIY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

9135:DBH
gene id: 9135:DBH
uniprot id: A0A8C9MJM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the copper type II ascorbate-dependent monooxygenase family.
messages: Conversion of dopamine to noradrenaline.
messages: Homotetramer; composed of two disulfide-linked dimers.
messages: chromaffin granule lumen
messages: chromaffin granule membrane
messages: secretory vesicle lumen
messages: secretory vesicle membrane

9135:ARPC1A
gene id: 9135:ARPC1A
uniprot id: A0A8C9N3H9
names: Function
names: Similarity
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.

9135:NEK6
gene id: 9135:NEK6
uniprot id: A0A8C9NUM2
names: Similarity
messages: Belongs to the protein kinase superfamily.

9135:CDK7
gene id: 9135:CDK7
uniprot id: A0A8C9UA44
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

9135:SUMF2
gene id: 9135:SUMF2
uniprot id: A0A8C9MW55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase-modifying factor family.
messages: Endoplasmic reticulum lumen

9135:AK1
gene id: 9135:AK1
uniprot id: A0A8C9UBE7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK1 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

9135:NDUFAF1
gene id: 9135:NDUFAF1
uniprot id: A0A8C9MFZ2
names: Function
names: Similarity
messages: As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.
messages: Belongs to the CIA30 family.

9135:LOC103816381
gene id: 9135:LOC103816381
uniprot id: A0A8C9NX31
uniprot id: A0A8C9UI23
names: Similarity
messages: Belongs to the PICALM/SNAP91 family.

9135:GDF5
gene id: 9135:GDF5
uniprot id: A0A8C9UEH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

9135:UBE2E1
gene id: 9135:UBE2E1
uniprot id: A0A8C9NQJ2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9135:NFYB
gene id: 9135:NFYB
uniprot id: A0A8C9MGE8
names: Function
names: Similarity
messages: Belongs to the NFYB/HAP3 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.

9135:EXTL2
gene id: 9135:EXTL2
uniprot id: A0A8C9NDS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

9135:TK1
gene id: 9135:TK1
uniprot id: A0A8C9N8V2
names: Similarity
messages: Belongs to the thymidine kinase family.

9135:GGPS1
gene id: 9135:GGPS1
uniprot id: A0A8C9MLE1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

9135:SLC7A11
gene id: 9135:SLC7A11
uniprot id: A0A8C9NKV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Cell membrane
messages: Membrane

9135:STX19
gene id: 9135:STX19
uniprot id: A0A8C9NKC4
names: Similarity
messages: Belongs to the syntaxin family.

9135:LOC103819047
gene id: 9135:LOC103819047
uniprot id: A0A8C9MUZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family. Highly divergent.
messages: Interacts with LRP2; LRP2 mediates APOM renal uptake and subsequent lysosomal degradation.
messages: Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid.
messages: Secreted

9135:WARS2
gene id: 9135:WARS2
uniprot id: A0A8C9N9U2
uniprot id: A0A8C9UED5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9135:PPP1R15B
gene id: 9135:PPP1R15B
uniprot id: A0A8C9N4N4
names: Similarity
messages: Belongs to the PPP1R15 family.

9135:YAE1
gene id: 9135:YAE1
uniprot id: A0A8C9NWC8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9135:LOC103817883
gene id: 9135:LOC103817883
uniprot id: A0A8C9NAX5
names: Similarity
messages: Belongs to the 3-beta-HSD family.

9135:SERPIND1
gene id: 9135:SERPIND1
uniprot id: A0A8C9MML6
names: Similarity
messages: Belongs to the serpin family.

9135:ARPP19
gene id: 9135:ARPP19
uniprot id: A0A8C9KQQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.

9135:FRG1
gene id: 9135:FRG1
uniprot id: A0A8C9N727
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRG1 family.
messages: Cajal body
messages: nucleolus

9135:FMC1
gene id: 9135:FMC1
uniprot id: A0A8C9MSX6
names: Similarity
messages: Belongs to the FMC1 family.

9135:SMPD2
gene id: 9135:SMPD2
uniprot id: A0A8C9UHE0
names: Similarity
messages: Belongs to the neutral sphingomyelinase family.

9135:LOC103814634
gene id: 9135:LOC103814634
uniprot id: A0A8C9N6X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9135:RECQL
gene id: 9135:RECQL
uniprot id: A0A8C9MY27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecQ subfamily.
messages: Nucleus

9135:WNT6
gene id: 9135:WNT6
uniprot id: A0A8C9NJN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9135:PIAS2
gene id: 9135:PIAS2
uniprot id: A0A8C9NSS5
names: Similarity
messages: Belongs to the PIAS family.

9135:LRRC8D
gene id: 9135:LRRC8D
uniprot id: A0A8C9UGQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

9135:USP18
gene id: 9135:USP18
uniprot id: A0A8C9MRR8
names: Similarity
messages: Belongs to the peptidase C19 family.

9135:LOC103812327
gene id: 9135:LOC103812327
uniprot id: A0A8C9NTL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMP-30/CGR1 family.
messages: Cytoplasm

9135:IL13RA2
gene id: 9135:IL13RA2
uniprot id: A0A8C9NUW0
names: Subcellular Location Annotation
messages: Membrane

9135:CRHR2
gene id: 9135:CRHR2
uniprot id: A0A8C9MV84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Membrane

9135:NBL1
gene id: 9135:NBL1
uniprot id: A0A8C9KWD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

9135:PKP1
gene id: 9135:PKP1
uniprot id: A0A8C9UBV7
names: Similarity
messages: Belongs to the beta-catenin family.

9135:DTX3L
gene id: 9135:DTX3L
uniprot id: A0A8C9NCE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

9135:TGFBR1
gene id: 9135:TGFBR1
uniprot id: A0A8C9NTP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

9135:NMT1
gene id: 9135:NMT1
uniprot id: A0A8C9MZ49
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

9135:CAV3
gene id: 9135:CAV3
uniprot id: A0A8C9NQT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

9135:LOC103816499
gene id: 9135:LOC103816499
uniprot id: A0A8C9UI68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

9135:HYCC1
gene id: 9135:HYCC1
uniprot id: A0A8C9NLV6
uniprot id: A0A8C9NNP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Hyccin family.
messages: Cell membrane
messages: Membrane
messages: cytosol

9135:LOC103814362
gene id: 9135:LOC103814362
uniprot id: A0A8C9UFP2
names: Subcellular Location Annotation
messages: Nucleus

9135:PRKD3
gene id: 9135:PRKD3
uniprot id: A0A8C9NDJ4
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by DAG and phorbol esters.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Cytoplasm
messages: Membrane

9135:CERCAM
gene id: 9135:CERCAM
uniprot id: A0A8C9UBB1
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

9135:STEAP4
gene id: 9135:STEAP4
uniprot id: A0A8C9NE24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

9135:LOC103824233
gene id: 9135:LOC103824233
uniprot id: A0A8C9NXB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9135:TAF12
gene id: 9135:TAF12
uniprot id: A0A8C9NDI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF12 family.
messages: Nucleus

9135:SNAP23
gene id: 9135:SNAP23
uniprot id: A0A8C9L546
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: synaptosome

9135:TRAK1
gene id: 9135:TRAK1
uniprot id: A0A8C9L575
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the milton family.
messages: Early endosome
messages: Mitochondrion

9135:GPR182
gene id: 9135:GPR182
uniprot id: A0A8C9MJ10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9135:UBA52
gene id: 9135:UBA52
uniprot id: A0A8C9NF23
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Nucleus

9135:ADCY7
gene id: 9135:ADCY7
uniprot id: A0A8C9U703
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

9135:EME1
gene id: 9135:EME1
uniprot id: A0A8C9KTD0
uniprot id: A0A8C9KVP4
names: Similarity
messages: Belongs to the EME1/MMS4 family.

9135:RARB
gene id: 9135:RARB
uniprot id: A0A8C9NKE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

9135:COL4A6
gene id: 9135:COL4A6
uniprot id: A0A8C9NUT3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

9135:TRMT5
gene id: 9135:TRMT5
uniprot id: A0A8C9MRK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM5 / TYW2 family.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Mitochondrion matrix
messages: Monomer.
messages: Nucleus
messages: Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.

9135:NAT9
gene id: 9135:NAT9
uniprot id: A0A8C9KVV5
names: Similarity
messages: Belongs to the acetyltransferase family. GNAT subfamily.

9135:RBM5
gene id: 9135:RBM5
uniprot id: A0A8C9NW74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RBM5/RBM10 family.
messages: Nucleus

9135:EXOC1
gene id: 9135:EXOC1
uniprot id: A0A8C9N4C6
uniprot id: A0A8C9UCL3
names: Similarity
messages: Belongs to the SEC3 family.

9135:HMGB3
gene id: 9135:HMGB3
uniprot id: A0A8C9NRY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

9135:RPL22L1
gene id: 9135:RPL22L1
uniprot id: A0A8C9N616
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

9135:ATP11B
gene id: 9135:ATP11B
uniprot id: A0A8C9UF82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

9135:LOC103812489
gene id: 9135:LOC103812489
uniprot id: A0A8C9L164
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

9135:PAQR3
gene id: 9135:PAQR3
uniprot id: A0A8C9MN71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

9135:SQSTM1
gene id: 9135:SQSTM1
uniprot id: A0A8C9NAA1
uniprot id: A0A8C9NCJ8
names: Subcellular Location Annotation
messages: autophagosome

9135:GPLD1
gene id: 9135:GPLD1
uniprot id: A0A8C9KWB3
uniprot id: A0A8C9MEW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPLD1 family.
messages: Secreted

9135:ZNF326
gene id: 9135:ZNF326
uniprot id: A0A8C9NKK1
uniprot id: A0A8C9NMB8
names: Similarity
messages: Belongs to the AKAP95 family.

9135:ACVR2A
gene id: 9135:ACVR2A
uniprot id: A0A8C9N1Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

9135:PROM1
gene id: 9135:PROM1
uniprot id: A0A8C9KVW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prominin family.
messages: Membrane
messages: microvillus membrane

9135:TRAPPC11
gene id: 9135:TRAPPC11
uniprot id: A0A8C9N446
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPPC11 family.
messages: Involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage.
messages: cis-Golgi network

9135:TAF1B
gene id: 9135:TAF1B
uniprot id: A0A8C9NBC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRN7/TAF1B family.
messages: nucleolus

9135:HTR2B
gene id: 9135:HTR2B
uniprot id: A0A8C9UGM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: synaptosome

9135:PARVA
gene id: 9135:PARVA
uniprot id: A0A8C9NY53
names: Similarity
messages: Belongs to the parvin family.

9135:FAM163A
gene id: 9135:FAM163A
uniprot id: A0A8C9N7H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

9135:PTPN14
gene id: 9135:PTPN14
uniprot id: A0A8C9U923
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

9135:RFTN1
gene id: 9135:RFTN1
uniprot id: A0A8C9UGZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the raftlin family.
messages: Cell membrane
messages: Membrane

9135:FZD10
gene id: 9135:FZD10
uniprot id: A0A8C9NAM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

9135:DNAJA4
gene id: 9135:DNAJA4
uniprot id: A0A8C9NDT4
names: Subcellular Location Annotation
messages: Membrane

9135:SLC26A9
gene id: 9135:SLC26A9
uniprot id: A0A8C9N8P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Ion transporter that can act both as an ion channel and anion exchanger. Mainly acts as a chloride channel, which mediate uncoupled chloride anion transport in an alternate-access mechanism where a saturable binding site is alternately exposed to either one or the other side of the membrane. Also acts as a DIDS- and thiosulfate- sensitive anion exchanger the exchange of chloride for bicarbonate ions across the cell membrane.
messages: Membrane

9135:CNRIP1
gene id: 9135:CNRIP1
uniprot id: A0A8C9L2Y1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CNRIP family.
messages: Interacts with the cannabinoid receptor CNR1 (via C-terminus). Does not interact with cannabinoid receptor CNR2.
messages: Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels.

9135:VKORC1L1
gene id: 9135:VKORC1L1
uniprot id: A0A8C9MVL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9135:NDUFA6
gene id: 9135:NDUFA6
uniprot id: A0A8C9MTA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I LYR family.
messages: Mammalian complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9135:IDS
gene id: 9135:IDS
uniprot id: A0A8C9NVG1
names: Similarity
messages: Belongs to the sulfatase family.

9135:AP5M1
gene id: 9135:AP5M1
uniprot id: A0A8C9MQT4
names: Subcellular Location Annotation
names: Subunit
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane
messages: Probably part of the adaptor protein complex 5 (AP-5) a tetramer composed of AP5B1, AP5M1, AP5S1 and AP5Z1.

9135:NAA35
gene id: 9135:NAA35
uniprot id: A0A8C9U6T0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MAK10 family.
messages: Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.
messages: Cytoplasm

9135:GOLT1A
gene id: 9135:GOLT1A
uniprot id: A0A8C9N7E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

9135:EPHA1
gene id: 9135:EPHA1
uniprot id: A0A8C9NPJ7
names: Subcellular Location Annotation
messages: Membrane

9135:CMKLR2
gene id: 9135:CMKLR2
uniprot id: A0A8C9MFL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

9135:NBR1
gene id: 9135:NBR1
uniprot id: A0A8C9MVY9
names: Subcellular Location Annotation
messages: autophagosome

9135:LOC103821609
gene id: 9135:LOC103821609
uniprot id: A0A8C9MXJ8
names: Similarity
messages: Belongs to the intermediate filament family.

9135:DAD1
gene id: 9135:DAD1
uniprot id: A0A8C9MS80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DAD/OST2 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

9135:CRKL
gene id: 9135:CRKL
uniprot id: A0A8C9MJA6
names: Similarity
messages: Belongs to the CRK family.

9135:FSHR
gene id: 9135:FSHR
uniprot id: A0A8C9NE96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.
messages: Membrane

9135:USP44
gene id: 9135:USP44
uniprot id: A0A8C9MXH2
names: Similarity
messages: Belongs to the peptidase C19 family.

9135:EXO1
gene id: 9135:EXO1
uniprot id: A0A8C9N0H2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.
messages: Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Nucleus

9135:NAGA
gene id: 9135:NAGA
uniprot id: A0A8C9MSD1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Homodimer.
messages: Lysosome

9135:FKBP4
gene id: 9135:FKBP4
uniprot id: A0A8C9NRC2
names: Subcellular Location Annotation
messages: Mitochondrion
messages: cytoskeleton
messages: cytosol

9135:STX6
gene id: 9135:STX6
uniprot id: A0A8C9KPW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Golgi apparatus membrane

9135:LOC103816492
gene id: 9135:LOC103816492
uniprot id: A0A8C9NS93
names: Similarity
messages: Belongs to the SUA5 family.

9135:TDO2
gene id: 9135:TDO2
uniprot id: A0A8C9NCB7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer. Dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:PGAP2
gene id: 9135:PGAP2
uniprot id: A0A8C9NWQ5
uniprot id: A0A8C9NX86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP2 family.
messages: Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface.
messages: Membrane

9135:POLR3K
gene id: 9135:POLR3K
uniprot id: A0A8C9NBT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

9135:KPNA5
gene id: 9135:KPNA5
uniprot id: A0A8C9NMH6
names: Similarity
messages: Belongs to the importin alpha family.

9135:QPCT
gene id: 9135:QPCT
uniprot id: A0A8C9UFC3
names: Similarity
messages: Belongs to the glutaminyl-peptide cyclotransferase family.

9135:LOC103822348
gene id: 9135:LOC103822348
uniprot id: A0A8C9L1C3
names: Similarity
messages: Belongs to the GST superfamily. Mu family.

9135:PRKX
gene id: 9135:PRKX
uniprot id: A0A8C9MPS6
names: Similarity
messages: Belongs to the protein kinase superfamily.

9135:NCAPG
gene id: 9135:NCAPG
uniprot id: A0A8C9MEE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND3 (condensin subunit 3) family.
messages: Chromosome

9135:VPS18
gene id: 9135:VPS18
uniprot id: A0A8C9MG61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS18 family.
messages: Membrane

9135:HINT1
gene id: 9135:HINT1
uniprot id: A0A8C9NJ94
names: Similarity
messages: Belongs to the HINT family.

9135:PTPN2
gene id: 9135:PTPN2
uniprot id: A0A8C9MZL9
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

9135:ESRRG
gene id: 9135:ESRRG
uniprot id: A0A8C9MSD7
uniprot id: A0A8C9MSQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

9135:CDA
gene id: 9135:CDA
uniprot id: A0A8C9MEB1
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

9135:ATXN1
gene id: 9135:ATXN1
uniprot id: A0A8C9L149
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

9135:MYLK
gene id: 9135:MYLK
uniprot id: A0A8C9N947
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

9135:LOC103823857
gene id: 9135:LOC103823857
uniprot id: A0A8C9MYK2
names: Subcellular Location Annotation
messages: Membrane

9135:RSPO3
gene id: 9135:RSPO3
uniprot id: A0A8C9NN51
names: Similarity
messages: Belongs to the R-spondin family.

9135:GCLC
gene id: 9135:GCLC
uniprot id: A0A8C9NBT8
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 3 family.

9135:ERGIC3
gene id: 9135:ERGIC3
uniprot id: A0A8C9NCG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

9135:LSM4
gene id: 9135:LSM4
uniprot id: A0A8C9NPA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

9135:ANXA8L1
gene id: 9135:ANXA8L1
uniprot id: A0A8C9UIW5
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

9135:ENKUR
gene id: 9135:ENKUR
uniprot id: A0A8C9N7N2
names: Subcellular Location Annotation
messages: cilium axoneme

9135:SLC9A9
gene id: 9135:SLC9A9
uniprot id: A0A8C9NRQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Endosome membrane
messages: Recycling endosome membrane

9135:PRKN
gene id: 9135:PRKN
uniprot id: A0A8C9NBE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RBR family. Parkin subfamily.
messages: Forms an E3 ubiquitin ligase complex.
messages: Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.
messages: Mitochondrion
messages: cytosol

9135:LOC103819267
gene id: 9135:LOC103819267
uniprot id: A0A8C9NN98
names: Similarity
messages: Belongs to the RIN (Ras interaction/interference) family.

9135:TADA1
gene id: 9135:TADA1
uniprot id: A0A8C9NS21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TADA1 family.
messages: Nucleus
messages: Probably involved in transcriptional regulation.

9135:LOC103819133
gene id: 9135:LOC103819133
uniprot id: A0A8C9MK25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Mitochondrion inner membrane
messages: Probably involved in the biogenesis of the COX complex.

9135:PGM1
gene id: 9135:PGM1
uniprot id: A0A8C9MVU0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

9135:B3GAT1
gene id: 9135:B3GAT1
uniprot id: A0A8C9N751
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

9135:INPP5K
gene id: 9135:INPP5K
uniprot id: A0A8C9MWB2
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.

9135:RGS4
gene id: 9135:RGS4
uniprot id: A0A8C9NZ47
names: Function
messages: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein.

9135:TRMT2B
gene id: 9135:TRMT2B
uniprot id: A0A8C9NX72
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:GJD2
gene id: 9135:GJD2
uniprot id: A0A8C9NBH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9135:LARS1
gene id: 9135:LARS1
uniprot id: A0A8C9KUJ2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9135:GPHB5
gene id: 9135:GPHB5
uniprot id: A0A8C9MSM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

9135:RAB3IL1
gene id: 9135:RAB3IL1
uniprot id: A0A8C9N369
names: Similarity
messages: Belongs to the SEC2 family.

9135:TMEM47
gene id: 9135:TMEM47
uniprot id: A0A8C9UEJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

9135:L3MBTL3
gene id: 9135:L3MBTL3
uniprot id: A0A8C9NJU6
names: Subcellular Location Annotation
messages: Nucleus

9135:LOC103817973
gene id: 9135:LOC103817973
uniprot id: A0A8C9KW65
names: Similarity
messages: Belongs to the gonadal family.

9135:EFEMP1
gene id: 9135:EFEMP1
uniprot id: A0A8C9NM68
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:MCEE
gene id: 9135:MCEE
uniprot id: A0A8C9NSZ5
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

9135:LOC108963022
gene id: 9135:LOC108963022
uniprot id: A0A8C9MVA6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

9135:LOC103819066
gene id: 9135:LOC103819066
uniprot id: A0A8C9N955
names: Subcellular Location Annotation
messages: Membrane

9135:IL2RG
gene id: 9135:IL2RG
uniprot id: A0A8C9NSS2
names: Subcellular Location Annotation
messages: Membrane

9135:ETFA
gene id: 9135:ETFA
uniprot id: A0A8C9NEA0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

9135:TRH
gene id: 9135:TRH
uniprot id: A0A8C9NUM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRH family.
messages: Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
messages: Secreted

9135:ISCU
gene id: 9135:ISCU
uniprot id: A0A8C9MV42
names: Similarity
messages: Belongs to the NifU family.

9135:SLC25A47
gene id: 9135:SLC25A47
uniprot id: A0A8C9MVK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9135:GPN2
gene id: 9135:GPN2
uniprot id: A0A8C9MY73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

9135:SLC16A3
gene id: 9135:SLC16A3
uniprot id: A0A8C9N911
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

9135:TICAM1
gene id: 9135:TICAM1
uniprot id: A0A8C9MW61
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer. Found in a multi-helicase-TICAM1 complex at least composed of DHX36, DDX1, DDX21 and TICAM1.
messages: Involved in innate immunity against invading pathogens. Adapter used by TLR3, TLR4 (through TICAM2) and TLR5 to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively. Phosphorylation by TBK1 on the pLxIS motif leads to recruitment and subsequent activation of the transcription factor IRF3 to induce expression of type I interferon and exert a potent immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of pro-inflammatory cytokines.
messages: Mitochondrion
messages: The N-terminal region is essential for activation of the IFNB promoter activity.
messages: autophagosome
messages: cytosol

9135:HYLS1
gene id: 9135:HYLS1
uniprot id: A0A8C9NWA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HYLS1 family.
messages: centriole
messages: cilium

9135:SCARB1
gene id: 9135:SCARB1
uniprot id: A0A8C9N7F8
uniprot id: A0A8C9NAB3
names: Similarity
messages: Belongs to the CD36 family.

9135:TACC3
gene id: 9135:TACC3
uniprot id: A0A8C9NNK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

9135:NELL2
gene id: 9135:NELL2
uniprot id: A0A8C9MDM1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:CAMK1D
gene id: 9135:CAMK1D
uniprot id: A0A8C9UDL4
names: Similarity
messages: Belongs to the protein kinase superfamily.

9135:TOP3A
gene id: 9135:TOP3A
uniprot id: A0A8C9N1E4
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

9135:CLDN16
gene id: 9135:CLDN16
uniprot id: A0A8C9NQI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9135:COG2
gene id: 9135:COG2
uniprot id: A0A8C9MJ80
names: Similarity
messages: Belongs to the COG2 family.

9135:SIX3
gene id: 9135:SIX3
uniprot id: A0A8C9UE81
names: Subcellular Location Annotation
messages: Nucleus

9135:DNAJA1
gene id: 9135:DNAJA1
uniprot id: A0A8C9NAR5
names: Subcellular Location Annotation
messages: Membrane

9135:LOC103818711
gene id: 9135:LOC103818711
uniprot id: A0A8C9UH42
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

9135:LEPROT
gene id: 9135:LEPROT
uniprot id: A0A8C9MVT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

9135:CNIH3
gene id: 9135:CNIH3
uniprot id: A0A8C9UHI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

9135:TMEM184A
gene id: 9135:TMEM184A
uniprot id: A0A8C9N2N7
names: Subcellular Location Annotation
messages: Membrane

9135:GJA9
gene id: 9135:GJA9
uniprot id: A0A8C9NJQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9135:LIPI
gene id: 9135:LIPI
uniprot id: A0A8C9N8Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

9135:P2RX4
gene id: 9135:P2RX4
uniprot id: A0A8C9N2B4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

9135:KREMEN1
gene id: 9135:KREMEN1
uniprot id: A0A8C9MRV5
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6.

9135:STMN2
gene id: 9135:STMN2
uniprot id: A0A8C9MFR2
names: Similarity
messages: Belongs to the stathmin family.

9135:ORC6
gene id: 9135:ORC6
uniprot id: A0A8C9MLJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC6 family.
messages: Nucleus

9135:MRPL14
gene id: 9135:MRPL14
uniprot id: A0A8C9NKS8
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

9135:TFRC
gene id: 9135:TFRC
uniprot id: A0A8C9NNC8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Acts as a lipid sensor that regulates mitochondrial fusion by regulating activation of the JNK pathway.
messages: Homodimer; disulfide-linked.
messages: Melanosome
messages: Membrane
messages: Stearoylated.

9135:TELO2
gene id: 9135:TELO2
uniprot id: A0A8C9MGJ9
uniprot id: A0A8C9MGN1
names: Similarity
messages: Belongs to the TEL2 family.

9135:DGKE
gene id: 9135:DGKE
uniprot id: A0A8C9NMF9
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

9135:LOC103822889
gene id: 9135:LOC103822889
uniprot id: A0A8C9KZY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the APH-1 family.
messages: Component of the gamma-secretase complex.
messages: Membrane
messages: Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors.

9135:LOC103825221
gene id: 9135:LOC103825221
uniprot id: A0A8C9N2U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

9135:VPS37C
gene id: 9135:VPS37C
uniprot id: A0A8C9N7K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

9135:GPR17
gene id: 9135:GPR17
uniprot id: A0A8C9MI14
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9135:VPS29
gene id: 9135:VPS29
uniprot id: A0A8C9N066
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
messages: Belongs to the VPS29 family.
messages: Endosome membrane

9135:LOC103820330
gene id: 9135:LOC103820330
uniprot id: A0A8C9N5V9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9135:ATP6V0D1
gene id: 9135:ATP6V0D1
uniprot id: A0A8C9MRR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

9135:CDC42EP1
gene id: 9135:CDC42EP1
uniprot id: A0A8C9MLD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

9135:KDR
gene id: 9135:KDR
uniprot id: A0A8C9N450
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

9135:CIAO3
gene id: 9135:CIAO3
uniprot id: A0A8C9MU13
names: Similarity
messages: Belongs to the NARF family.

9135:BCL2A1
gene id: 9135:BCL2A1
uniprot id: A0A8C9MQN0
names: Similarity
messages: Belongs to the Bcl-2 family.

9135:CRIPT
gene id: 9135:CRIPT
uniprot id: A0A8C9N6D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRIPT family.
messages: Cytoplasm

9135:CUL4B
gene id: 9135:CUL4B
uniprot id: A0A8C9NSY6
names: Similarity
messages: Belongs to the cullin family.

9135:APPL1
gene id: 9135:APPL1
uniprot id: A0A8C9MGA5
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: Nucleus
messages: phagosome
messages: ruffle

9135:CNOT9
gene id: 9135:CNOT9
uniprot id: A0A8C9NDG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT9 family.
messages: P-body

9135:LOC103826648
gene id: 9135:LOC103826648
uniprot id: A0A8C9L295
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

9135:ACO1
gene id: 9135:ACO1
uniprot id: A0A8C9NGV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Cytoplasm

9135:BCO1
gene id: 9135:BCO1
uniprot id: A0A8C9MTI2
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

9135:DOCK2
gene id: 9135:DOCK2
uniprot id: A0A8C9N5Y3
names: Similarity
messages: Belongs to the DOCK family.

9135:LOC103826032
gene id: 9135:LOC103826032
uniprot id: A0A8C9NJ99
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

9135:FXR1
gene id: 9135:FXR1
uniprot id: A0A8C9NDU2
uniprot id: A0A8C9NDV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMR1 family.
messages: Cytoplasmic ribonucleoprotein granule

9135:KYNU
gene id: 9135:KYNU
uniprot id: A0A8C9N179
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:TMEM177
gene id: 9135:TMEM177
uniprot id: A0A8C9UFG0
names: Function
names: Similarity
messages: Belongs to the TMEM177 family.
messages: Plays a role in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation and is required for the stabilization of COX20 and the newly synthesized MT-CO2/COX2 protein.

9135:SLC35A3
gene id: 9135:SLC35A3
uniprot id: A0A8C9NH70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9135:GLYCTK
gene id: 9135:GLYCTK
uniprot id: A0A8C9NV52
names: Similarity
messages: Belongs to the glycerate kinase type-2 family.

9135:HNF4G
gene id: 9135:HNF4G
uniprot id: A0A8C9U152
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9135:HSPB3
gene id: 9135:HSPB3
uniprot id: A0A8C9N3K8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

9135:SLC8A3
gene id: 9135:SLC8A3
uniprot id: A0A8C9NJI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

9135:TCAF2
gene id: 9135:TCAF2
uniprot id: A0A8C9NQE9
names: Similarity
messages: Belongs to the TCAF family.

9135:CDKN3
gene id: 9135:CDKN3
uniprot id: A0A8C9MFH4
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

9135:USE1
gene id: 9135:USE1
uniprot id: A0A8C9U4Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the USE1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9135:HYCC2
gene id: 9135:HYCC2
uniprot id: A0A8C9MGP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Hyccin family.
messages: Cell membrane
messages: Membrane
messages: cytosol

9135:PPM1K
gene id: 9135:PPM1K
uniprot id: A0A8C9NQ40
names: Similarity
messages: Belongs to the PP2C family.

9135:BARX2
gene id: 9135:BARX2
uniprot id: A0A8C9NYE0
names: Subcellular Location Annotation
messages: Nucleus

9135:VPS13B
gene id: 9135:VPS13B
uniprot id: A0A8C9U7M4
names: Similarity
messages: Belongs to the VPS13 family.

9135:MFAP5
gene id: 9135:MFAP5
uniprot id: A0A8C9NMV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MFAP family.
messages: extracellular matrix

9135:LOC103817037
gene id: 9135:LOC103817037
uniprot id: A0A8C9MPR2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:WNT5B
gene id: 9135:WNT5B
uniprot id: A0A8C9MQJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9135:C8A
gene id: 9135:C8A
uniprot id: A0A8C9MTZ3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9135:TOP3B
gene id: 9135:TOP3B
uniprot id: A0A8C9MNL8
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

9135:COG4
gene id: 9135:COG4
uniprot id: A0A8C9MR48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG4 family.
messages: Golgi apparatus membrane

9135:COPS7B
gene id: 9135:COPS7B
uniprot id: A0A8C9NLU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
messages: Cytoplasm
messages: Nucleus

9135:IFNG
gene id: 9135:IFNG
uniprot id: A0A8C9MH47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II (or gamma) interferon family.
messages: Homodimer.
messages: Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
messages: Secreted

9135:SNCA
gene id: 9135:SNCA
uniprot id: Q91448
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Acetylation at Met-1 seems to be important for proper folding and native oligomeric structure.
messages: Belongs to the synuclein family.
messages: Brain.
messages: May be involved in neuronal plasticity.
messages: May be involved in the regulation of dopamine release and transport.
messages: Membrane
messages: Nucleus
messages: Secreted
messages: Synapse
messages: cytosol

9135:LHX8
gene id: 9135:LHX8
uniprot id: A0A8C9N1V2
names: Subcellular Location Annotation
messages: Nucleus

9135:KIF27
gene id: 9135:KIF27
uniprot id: A0A8C9MND6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9135:MTM1
gene id: 9135:MTM1
uniprot id: A0A8C9NUG6
uniprot id: A0A8C9NVS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

9135:MLH1
gene id: 9135:MLH1
uniprot id: A0A8C9N919
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: Nucleus

9135:TLCD1
gene id: 9135:TLCD1
uniprot id: A0A8C9MYS9
names: Subcellular Location Annotation
messages: Membrane

9135:SPC25
gene id: 9135:SPC25
uniprot id: A0A8C9NQK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC25 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

9135:CDX1
gene id: 9135:CDX1
uniprot id: A0A8C9NCN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

9135:ASCC1
gene id: 9135:ASCC1
uniprot id: A0A8C9NTG1
names: Subcellular Location Annotation
messages: Cytoplasm

9135:SQLE
gene id: 9135:SQLE
uniprot id: A0A8C9MXK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the squalene monooxygenase family.
messages: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
messages: Endoplasmic reticulum membrane

9135:GPX8
gene id: 9135:GPX8
uniprot id: A0A8C9N480
names: Similarity
messages: Belongs to the glutathione peroxidase family.

9135:D2HGDH
gene id: 9135:D2HGDH
uniprot id: A0A8C9N0K1
names: Similarity
messages: Belongs to the FAD-binding oxidoreductase/transferase type 4 family.

9135:GPR155
gene id: 9135:GPR155
uniprot id: A0A8C9NTB8
names: Subcellular Location Annotation
messages: Membrane

9135:LOC103819095
gene id: 9135:LOC103819095
uniprot id: A0A8C9NTV8
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

9135:C1H2orf49
gene id: 9135:C1H2orf49
uniprot id: A0A8C9MI59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ashwin family.
messages: Nucleus

9135:SIAH3
gene id: 9135:SIAH3
uniprot id: A0A8C9NGB0
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

9135:TARS1
gene id: 9135:TARS1
uniprot id: A0A8C9MEB3
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

9135:PLP1
gene id: 9135:PLP1
uniprot id: A0A8C9NT76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

9135:FOXN1
gene id: 9135:FOXN1
uniprot id: A0A8C9MWP8
names: Subcellular Location Annotation
messages: Nucleus

9135:TSC22D3
gene id: 9135:TSC22D3
uniprot id: A0A8C9NTI1
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

9135:UNC5C
gene id: 9135:UNC5C
uniprot id: A0A8C9NN38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

9135:VAMP7
gene id: 9135:VAMP7
uniprot id: A0A8C9NRB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

9135:RPL13
gene id: 9135:RPL13
uniprot id: A0A8C9MY20
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

9135:TRAPPC4
gene id: 9135:TRAPPC4
uniprot id: A0A8C9NRB7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

9135:MFSD9
gene id: 9135:MFSD9
uniprot id: A0A8C9MHZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

9135:GUK1
gene id: 9135:GUK1
uniprot id: A0A8C9MTZ4
names: Similarity
messages: Belongs to the guanylate kinase family.

9135:BUD23
gene id: 9135:BUD23
uniprot id: A0A8C9MMU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.
messages: Cytoplasm
messages: Nucleus

9135:DNMBP
gene id: 9135:DNMBP
uniprot id: A0A8C9NPY8
uniprot id: A0A8C9NTU9
names: Subcellular Location Annotation
messages: Cell junction
messages: Golgi stack
messages: Synapse
messages: cytoskeleton

9135:TEC
gene id: 9135:TEC
uniprot id: A0A8C9MZZ1
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

9135:ESD
gene id: 9135:ESD
uniprot id: A0A8C9NJL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the esterase D family.
messages: Cytoplasmic vesicle
messages: Serine hydrolase involved in the detoxification of formaldehyde.

9135:LOC103822978
gene id: 9135:LOC103822978
uniprot id: A0A8C9MRZ5
names: Subcellular Location Annotation
messages: Membrane

9135:FBLN1
gene id: 9135:FBLN1
uniprot id: A0A8C9MI57
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fibulin family.
messages: Homomultimerizes and interacts with various extracellular matrix components.
messages: Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9135:FAM13B
gene id: 9135:FAM13B
uniprot id: A0A8C9UE60
names: Similarity
messages: Belongs to the FAM13 family.

9135:RGR
gene id: 9135:RGR
uniprot id: A0A8C9MI02
names: Subcellular Location Annotation
messages: Membrane

9135:STX17
gene id: 9135:STX17
uniprot id: A0A8C9MY76
names: Similarity
messages: Belongs to the syntaxin family.

9135:OTULIN
gene id: 9135:OTULIN
uniprot id: A0A8C9MLW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C65 family. Otulin subfamily.
messages: Cytoplasm

9135:TMEM45A
gene id: 9135:TMEM45A
uniprot id: A0A8C9NTT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

9135:TENT5A
gene id: 9135:TENT5A
uniprot id: A0A8C9MNA1
names: Similarity
messages: Belongs to the TENT family.

9135:LOC103815314
gene id: 9135:LOC103815314
uniprot id: A0A8C9MJZ7
names: Subcellular Location Annotation
messages: Membrane

9135:SLC30A4
gene id: 9135:SLC30A4
uniprot id: A0A8C9MPW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

9135:TM4SF1
gene id: 9135:TM4SF1
uniprot id: A0A8C9N2Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

9135:LIPT1
gene id: 9135:LIPT1
uniprot id: A0A8C9NQ02
names: Similarity
messages: Belongs to the LplA family.

9135:LOC103827200
gene id: 9135:LOC103827200
uniprot id: A0A8C9NNM6
names: Subcellular Location Annotation
messages: Nucleus

9135:KBTBD8
gene id: 9135:KBTBD8
uniprot id: A0A8C9MYW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KBTBD8 family.
messages: Golgi apparatus
messages: spindle

9135:WNT4
gene id: 9135:WNT4
uniprot id: A0A8C9NTS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9135:DPCD
gene id: 9135:DPCD
uniprot id: A0A8C9UIG2
names: Similarity
messages: Belongs to the DPCD family.

9135:SLC6A15
gene id: 9135:SLC6A15
uniprot id: A0A8C9MZH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A15 subfamily.
messages: Membrane

9135:TP73
gene id: 9135:TP73
uniprot id: A0A8C9KXF9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Found in a complex with p53/TP53 and CABLES1.
messages: Nucleus
messages: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.

9135:RAB18
gene id: 9135:RAB18
uniprot id: A0A8C9N2W1
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Lipid droplet

9135:PDC
gene id: 9135:PDC
uniprot id: A0A8C9N852
names: Similarity
messages: Belongs to the phosducin family.

9135:FAM228B
gene id: 9135:FAM228B
uniprot id: A0A8C9NKJ1
names: Similarity
messages: Belongs to the FAM228 family.

9135:RETREG1
gene id: 9135:RETREG1
uniprot id: A0A8C9MLQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RETREG family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9135:TSPAN12
gene id: 9135:TSPAN12
uniprot id: A0A8C9KSV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9135:ITPR2
gene id: 9135:ITPR2
uniprot id: A0A8C9N303
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the InsP3 receptor family.
messages: Endoplasmic reticulum membrane
messages: Homotetramer.
messages: Membrane
messages: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
messages: The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.

9135:PDGFRA
gene id: 9135:PDGFRA
uniprot id: A0A8C9N183
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Interacts with homodimeric PDGFA, PDGFB and PDGFC, and with heterodimers formed by PDGFA and PDGFB. Monomer in the absence of bound ligand.
messages: Membrane
messages: Present in an inactive conformation in the absence of bound ligand. Binding of PDGFA and/or PDGFB leads to dimerization and activation by autophosphorylation on tyrosine residues.
messages: Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.

9135:AGK
gene id: 9135:AGK
uniprot id: A0A8C9UD84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AGK family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

9135:DEGS2
gene id: 9135:DEGS2
uniprot id: A0A8C9UBB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

9135:NPRL3
gene id: 9135:NPRL3
uniprot id: A0A8C9NAC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway.
messages: Belongs to the NPR3 family.
messages: Lysosome

9135:VIPAS39
gene id: 9135:VIPAS39
uniprot id: A0A8C9N1L8
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Endosome
messages: Late endosome

9135:CSF3
gene id: 9135:CSF3
uniprot id: A0A8C9N117
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

9135:LOC103826653
gene id: 9135:LOC103826653
uniprot id: A0A8C9L3E3
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

9135:RPS6
gene id: 9135:RPS6
uniprot id: A0A8C9KSJ7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

9135:PDCL
gene id: 9135:PDCL
uniprot id: A0A8C9NTY5
names: Similarity
messages: Belongs to the phosducin family.

9135:DUT
gene id: 9135:DUT
uniprot id: A0A8C9MQ52
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Involved in nucleotide metabolism via production of dUMP, the immediate precursor of thymidine nucleotides, and decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

9135:LOC103816715
gene id: 9135:LOC103816715
uniprot id: A0A8C9MU39
names: Subcellular Location Annotation
messages: Membrane
messages: Membrane raft
messages: Secreted

9135:PAPPA
gene id: 9135:PAPPA
uniprot id: A0A8C9MV12
names: Caution
names: Similarity
messages: Belongs to the peptidase M43B family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:EXOG
gene id: 9135:EXOG
uniprot id: A0A8C9MVN9
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

9135:COMTD1
gene id: 9135:COMTD1
uniprot id: A0A8C9MGS7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

9135:CPEB4
gene id: 9135:CPEB4
uniprot id: A0A8C9NPI9
names: Similarity
messages: Belongs to the RRM CPEB family.

9135:RPAP2
gene id: 9135:RPAP2
uniprot id: A0A8C9UG47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the RNA polymerase II complex.
messages: Belongs to the RPAP2 family.
messages: Nucleus
messages: Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated 'Ser-7' of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of 'Ser-5' of the CTD, thereby promoting transcription of snRNA genes.

9135:PPIL2
gene id: 9135:PPIL2
uniprot id: A0A8C9MMK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.
messages: Nucleus

9135:AMD1
gene id: 9135:AMD1
uniprot id: A0A8C9KPC0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic AdoMetDC family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.

9135:LOC103819904
gene id: 9135:LOC103819904
uniprot id: A0A8C9U6T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane

9135:TTC21B
gene id: 9135:TTC21B
uniprot id: A0A8C9NQ44
names: Similarity
messages: Belongs to the TTC21 family.

9135:SLC25A22
gene id: 9135:SLC25A22
uniprot id: A0A8C9NMV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9135:GPR65
gene id: 9135:GPR65
uniprot id: A0A8C9N3F8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9135:YKT6
gene id: 9135:YKT6
uniprot id: A0A8C9NQE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.

9135:DCLRE1A
gene id: 9135:DCLRE1A
uniprot id: A0A8C9NNB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

9135:SCARF1
gene id: 9135:SCARF1
uniprot id: A0A8C9MVZ2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:LOC103815885
gene id: 9135:LOC103815885
uniprot id: A0A8C9N8G3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:LOC103820034
gene id: 9135:LOC103820034
uniprot id: A0A8C9MLI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

9135:NFS1
gene id: 9135:NFS1
uniprot id: A0A8C9NDK6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

9135:KCNE3
gene id: 9135:KCNE3
uniprot id: A0A8C9NIH3
names: Similarity
messages: Belongs to the potassium channel KCNE family.

9135:NDRG4
gene id: 9135:NDRG4
uniprot id: A0A8C9UBE5
names: Similarity
messages: Belongs to the NDRG family.

9135:FNIP2
gene id: 9135:FNIP2
uniprot id: A0A8C9N7H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNIP family.
messages: Lysosome membrane
messages: Membrane

9135:LOC103827283
gene id: 9135:LOC103827283
uniprot id: A0A8C9MKX7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

9135:LOC103820557
gene id: 9135:LOC103820557
uniprot id: A0A8C9N8U3
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

9135:UVSSA
gene id: 9135:UVSSA
uniprot id: A0A8C9NQ00
names: Similarity
messages: Belongs to the UVSSA family.

9135:EIF3M
gene id: 9135:EIF3M
uniprot id: A0A8C9UCF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Belongs to the eIF-3 subunit M family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

9135:LOC103815911
gene id: 9135:LOC103815911
uniprot id: A0A8C9NGV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Endoplasmic reticulum membrane
messages: Lysosome
messages: Membrane
messages: phagosome

9135:CD14
gene id: 9135:CD14
uniprot id: A0A8C9N4R5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Golgi apparatus
messages: Membrane raft
messages: Secreted

9135:LOC103822176
gene id: 9135:LOC103822176
uniprot id: A0A8C9ND40
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

9135:MAP1LC3A
gene id: 9135:MAP1LC3A
uniprot id: A0A8C9MYA5
names: Similarity
messages: Belongs to the ATG8 family.

9135:MRPL42
gene id: 9135:MRPL42
uniprot id: A0A8C9MVR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL42 family.
messages: Mitochondrion

9135:C3H6orf58
gene id: 9135:C3H6orf58
uniprot id: A0A8C9NMF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEG1 family.
messages: Secreted

9135:RHAG
gene id: 9135:RHAG
uniprot id: A0A8C9NJZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

9135:LOC103816734
gene id: 9135:LOC103816734
uniprot id: A0A8C9UBJ5
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

9135:ASPN
gene id: 9135:ASPN
uniprot id: A0A8C9NEB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: extracellular matrix

9135:USP7
gene id: 9135:USP7
uniprot id: A0A8C9NAW2
names: Similarity
messages: Belongs to the peptidase C19 family.

9135:LOC103813328
gene id: 9135:LOC103813328
uniprot id: A0A8C9MUF9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9135:WTAP
gene id: 9135:WTAP
uniprot id: A0A8C9NBP6
names: Similarity
messages: Belongs to the fl(2)d family.

9135:TRAF6
gene id: 9135:TRAF6
uniprot id: A0A8C9U4W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family. A subfamily.
messages: Lipid droplet
messages: Nucleus
messages: cell cortex

9135:UNC50
gene id: 9135:UNC50
uniprot id: A0A8C9NSC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-50 family.
messages: Membrane
messages: Nucleus inner membrane

9135:MTERF2
gene id: 9135:MTERF2
uniprot id: A0A8C9MIL6
names: Similarity
messages: Belongs to the mTERF family.

9135:FAM83G
gene id: 9135:FAM83G
uniprot id: A0A8C9N1U5
names: Similarity
messages: Belongs to the FAM83 family.

9135:AKAP9
gene id: 9135:AKAP9
uniprot id: A0A8C9NFT8
names: Subcellular Location Annotation
messages: centrosome

9135:ALG5
gene id: 9135:ALG5
uniprot id: A0A8C9NHR0
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

9135:GALE
gene id: 9135:GALE
uniprot id: A0A8C9MUY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids.
messages: Homodimer.

9135:PDGFRL
gene id: 9135:PDGFRL
uniprot id: A0A8C9N6L8
names: Subunit
messages: Forms a complex composed of PDGFRL, TNK2 and GRB2.

9135:RBBP7
gene id: 9135:RBBP7
uniprot id: A0A8C9UGE6
names: Subcellular Location Annotation
messages: Nucleus

9135:PARVB
gene id: 9135:PARVB
uniprot id: A0A8C9N0H3
names: Similarity
messages: Belongs to the parvin family.

9135:NXT2
gene id: 9135:NXT2
uniprot id: A0A8C9NTN0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

9135:NDC80
gene id: 9135:NDC80
uniprot id: A0A8C9N3U7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the NDC80/HEC1 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

9135:TMEM229B
gene id: 9135:TMEM229B
uniprot id: A0A8C9UFK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM229 family.
messages: Membrane

9135:GNAL
gene id: 9135:GNAL
uniprot id: A0A8C9MYB8
uniprot id: A0A8C9N0P7
names: Similarity
messages: Belongs to the G-alpha family. G(s) subfamily.

9135:NMNAT3
gene id: 9135:NMNAT3
uniprot id: A0A8C9N2J8
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

9135:LOC103826887
gene id: 9135:LOC103826887
uniprot id: A0A8C9MYA2
names: Similarity
messages: Belongs to the serpin family.

9135:NUP155
gene id: 9135:NUP155
uniprot id: A0A8C9N023
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the non-repetitive/WGA-negative nucleoporin family.
messages: nuclear pore complex

9135:ELP1
gene id: 9135:ELP1
uniprot id: A0A8C9UE46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP1/IKA1 family.
messages: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
messages: Cytoplasm
messages: Nucleus

9135:PRCP
gene id: 9135:PRCP
uniprot id: A0A8C9MHQ6
names: Similarity
messages: Belongs to the peptidase S28 family.

9135:MESD
gene id: 9135:MESD
uniprot id: A0A8C9MQX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MESD family.
messages: Endoplasmic reticulum

9135:PDE7A
gene id: 9135:PDE7A
uniprot id: A0A8C9NKC6
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9135:LOC103814999
gene id: 9135:LOC103814999
uniprot id: A0A8C9MIM0
names: Similarity
messages: Belongs to the cytochrome P450 family.

9135:ATPAF2
gene id: 9135:ATPAF2
uniprot id: A0A8C9N3P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

9135:LOC103822562
gene id: 9135:LOC103822562
uniprot id: A0A8C9NNQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

9135:ATP13A4
gene id: 9135:ATP13A4
uniprot id: A0A8C9UGX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

9135:TMEM269
gene id: 9135:TMEM269
uniprot id: A0A8C9MJ73
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

9135:MRPL58
gene id: 9135:MRPL58
uniprot id: A0A8C9KTT7
names: Subcellular Location Annotation
messages: Mitochondrion

9135:LOC103813356
gene id: 9135:LOC103813356
uniprot id: A0A8C9MU99
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9135:TBPL1
gene id: 9135:TBPL1
uniprot id: A0A8C9NC34
names: Similarity
messages: Belongs to the TBP family.

9135:WASHC3
gene id: 9135:WASHC3
uniprot id: A0A8C9N6U8
names: Similarity
messages: Belongs to the CCDC53 family.

9135:BCAT1
gene id: 9135:BCAT1
uniprot id: A0A8C9MXI4
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

9135:TM4SF4
gene id: 9135:TM4SF4
uniprot id: A0A8C9N252
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

9135:CROT
gene id: 9135:CROT
uniprot id: A0A8C9NBL8
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

9135:DPT
gene id: 9135:DPT
uniprot id: A0A8C9N399
names: Similarity
messages: Belongs to the dermatopontin family.

9135:NADK
gene id: 9135:NADK
uniprot id: A0A8C9NYH2
uniprot id: A0A8C9NZ05
names: Similarity
messages: Belongs to the NAD kinase family.

9135:VDAC2
gene id: 9135:VDAC2
uniprot id: A0A8C9MGS2
names: Similarity
messages: Belongs to the eukaryotic mitochondrial porin family.

9135:RNASEH2B
gene id: 9135:RNASEH2B
uniprot id: A0A8C9NF77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H2 subunit B family.
messages: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Nucleus
messages: The RNase H2 complex is a heterotrimer composed of the catalytic subunit RNASEH2A and the non-catalytic subunits RNASEH2B and RNASEH2C.

9135:AQP9
gene id: 9135:AQP9
uniprot id: A0A8C9KPV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

9135:DUSP7
gene id: 9135:DUSP7
uniprot id: A0A8C9NWB9
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

9135:LOC103824282
gene id: 9135:LOC103824282
uniprot id: A0A8C9NXV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-5A synthase family.
messages: Cytoplasm

9135:TEAD4
gene id: 9135:TEAD4
uniprot id: A0A8C9NQN9
names: Subcellular Location Annotation
messages: Nucleus

9135:COMT
gene id: 9135:COMT
uniprot id: A0A8C9MMT8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.

9135:UBE2T
gene id: 9135:UBE2T
uniprot id: A0A8C9MWW4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9135:TMEM192
gene id: 9135:TMEM192
uniprot id: A0A8C9N6B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM192 family.
messages: Late endosome
messages: Lysosome membrane
messages: Membrane

9135:LOC103823445
gene id: 9135:LOC103823445
uniprot id: A0A8C9U8R9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Homodimer.
messages: Secreted

9135:TNFRSF11B
gene id: 9135:TNFRSF11B
uniprot id: A0A8C9MW24
names: Caution
names: Function
names: Subunit
messages: Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:JPH3
gene id: 9135:JPH3
uniprot id: A0A8C9MW11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

9135:FOXM1
gene id: 9135:FOXM1
uniprot id: A0A8C9UH09
names: Subcellular Location Annotation
messages: Nucleus

9135:TIMM13
gene id: 9135:TIMM13
uniprot id: A0A8C9L366
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

9135:SMPX
gene id: 9135:SMPX
uniprot id: A0A8C9NLF6
names: Function
names: Similarity
messages: Belongs to the SMPX family.
messages: Plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair.

9135:GPN3
gene id: 9135:GPN3
uniprot id: A0A8C9UD31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

9135:LAMA2
gene id: 9135:LAMA2
uniprot id: A0A8C9NJ65
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

9135:ATG13
gene id: 9135:ATG13
uniprot id: A0A8C9MHN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG13 family. Metazoan subfamily.
messages: Preautophagosomal structure

9135:TRADD
gene id: 9135:TRADD
uniprot id: A0A8C9MP40
names: Subcellular Location Annotation
messages: Nucleus
messages: cytoskeleton

9135:CFH
gene id: 9135:CFH
uniprot id: A0A8C9NA63
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:SMG5
gene id: 9135:SMG5
uniprot id: A0A8C9NH53
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Plays a role in nonsense-mediated mRNA decay.

9135:ENY2
gene id: 9135:ENY2
uniprot id: A0A8C9UB64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ENY2 family.
messages: Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2). Component of the SAGA transcription coactivator-HAT complex. Within the SAGA complex, participates to a subcomplex of SAGA called the DUB module (deubiquitination module).
messages: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
messages: nucleoplasm

9135:KRR1
gene id: 9135:KRR1
uniprot id: A0A8C9N0L5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KRR1 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
messages: nucleolus

9135:KDELR3
gene id: 9135:KDELR3
uniprot id: A0A8C9MMQ8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9135:GAL
gene id: 9135:GAL
uniprot id: A0A8C9MKC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galanin family.
messages: Secreted

9135:PSMD5
gene id: 9135:PSMD5
uniprot id: A0A8C9L4D0
names: Similarity
messages: Belongs to the proteasome subunit S5B/HSM3 family.

9135:DNAJA2
gene id: 9135:DNAJA2
uniprot id: A0A8C9MLZ7
names: Subcellular Location Annotation
messages: Membrane

9135:ZC3H12C
gene id: 9135:ZC3H12C
uniprot id: A0A8C9MNT9
names: Similarity
messages: Belongs to the ZC3H12 family.

9135:PRMT7
gene id: 9135:PRMT7
uniprot id: A0A8C9U7U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.
messages: Nucleus
messages: cytosol

9135:SLC27A4
gene id: 9135:SLC27A4
uniprot id: A0A8C9MT11
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

9135:MIEF2
gene id: 9135:MIEF2
uniprot id: A0A8C9N1Z5
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

9135:MRPS33
gene id: 9135:MRPS33
uniprot id: A0A8C9N698
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS33 family.
messages: Mitochondrion

9135:LOC103820493
gene id: 9135:LOC103820493
uniprot id: A0A8C9MVW0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9135:KCNC1
gene id: 9135:KCNC1
uniprot id: A0A8C9MQ03
names: Subcellular Location Annotation
messages: Membrane

9135:PLAU
gene id: 9135:PLAU
uniprot id: A0A8C9MGI3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:UPP2
gene id: 9135:UPP2
uniprot id: A0A8C9MNB5
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

9135:CCND2
gene id: 9135:CCND2
uniprot id: A0A8C9N2L6
names: Similarity
messages: Belongs to the cyclin family.

9135:MAGT1
gene id: 9135:MAGT1
uniprot id: A0A8C9NUI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9135:PTPRB
gene id: 9135:PTPRB
uniprot id: A0A8C9N3S2
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily.

9135:CLN8
gene id: 9135:CLN8
uniprot id: A0A8C9NDB0
names: Subcellular Location Annotation
messages: Membrane

9135:TMEM43
gene id: 9135:TMEM43
uniprot id: A0A8C9MPA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM43 family.
messages: Membrane

9135:SLCO2A1
gene id: 9135:SLCO2A1
uniprot id: A0A8C9U942
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9135:LTV1
gene id: 9135:LTV1
uniprot id: A0A8C9NNM7
names: Similarity
messages: Belongs to the LTV1 family.

9135:CHRNA4
gene id: 9135:CHRNA4
uniprot id: A0A8C9UGN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9135:AOX1
gene id: 9135:AOX1
uniprot id: A0A8C9MGW2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Cytoplasm
messages: Homodimer.

9135:GOT2
gene id: 9135:GOT2
uniprot id: A0A8C9UA67
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

9135:IRF1
gene id: 9135:IRF1
uniprot id: A0A8C9N7R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Nucleus

9135:LOC103813306
gene id: 9135:LOC103813306
uniprot id: A0A8C9MGG3
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

9135:ITPKA
gene id: 9135:ITPKA
uniprot id: A0A8C9MFZ9
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

9135:DRGX
gene id: 9135:DRGX
uniprot id: A0A8C9NTG8
names: Subcellular Location Annotation
messages: Nucleus

9135:LOC103814477
gene id: 9135:LOC103814477
uniprot id: A0A8C9KYB5
names: Similarity
messages: Belongs to the cytochrome P450 family.

9135:LOC103824319
gene id: 9135:LOC103824319
uniprot id: A0A8C9KWD1
names: Similarity
messages: Belongs to the ADP-ribosyl cyclase family.

9135:PTP4A1
gene id: 9135:PTP4A1
uniprot id: A0A8C9UCZ1
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

9135:SLC7A6
gene id: 9135:SLC7A6
uniprot id: A0A8C9MNZ0
names: Subcellular Location Annotation
messages: Membrane

9135:P2RX1
gene id: 9135:P2RX1
uniprot id: A0A8C9MR72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

9135:KDM5B
gene id: 9135:KDM5B
uniprot id: A0A8C9MUJ3
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.

9135:DDR2
gene id: 9135:DDR2
uniprot id: A0A8C9NYB2
names: Subcellular Location Annotation
messages: Membrane

9135:FAM114A1
gene id: 9135:FAM114A1
uniprot id: A0A8C9MPM5
names: Similarity
messages: Belongs to the FAM114 family.

9135:ACVR1B
gene id: 9135:ACVR1B
uniprot id: A0A8C9UBP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

9135:UCHL5
gene id: 9135:UCHL5
uniprot id: A0A8C9UEC7
names: Similarity
messages: Belongs to the peptidase C12 family.

9135:TPK1
gene id: 9135:TPK1
uniprot id: A0A8C9NQV7
uniprot id: A0A8C9NT10
names: Similarity
messages: Belongs to the thiamine pyrophosphokinase family.

9135:SF3B6
gene id: 9135:SF3B6
uniprot id: A0A8C9NKI0
names: Subcellular Location Annotation
messages: Nucleus

9135:DES
gene id: 9135:DES
uniprot id: A0A8C9NKN5
names: Similarity
messages: Belongs to the intermediate filament family.

9135:ST14
gene id: 9135:ST14
uniprot id: A0A8C9NRU0
uniprot id: A0A8C9UIG1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9135:LZIC
gene id: 9135:LZIC
uniprot id: A0A8C9NVW6
names: Similarity
messages: Belongs to the CTNNBIP1 family.

9135:NEU2
gene id: 9135:NEU2
uniprot id: A0A8C9MIK9
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

9135:PDPK1
gene id: 9135:PDPK1
uniprot id: A0A8C9MHQ5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.

9135:LIN7C
gene id: 9135:LIN7C
uniprot id: A0A8C9MY93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-7 family.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.

9135:ITK
gene id: 9135:ITK
uniprot id: A0A8C9NI55
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

9135:PARK7
gene id: 9135:PARK7
uniprot id: A0A8C9MH38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C56 family.
messages: Membrane raft

9135:ACSF3
gene id: 9135:ACSF3
uniprot id: A0A8C9MXI8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

9135:SLC26A3
gene id: 9135:SLC26A3
uniprot id: A0A8C9MUE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Mediates chloride-bicarbonate exchange with a chloride bicarbonate stoichiometry of 2:1 in the intestinal epithelia. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation.
messages: Membrane

9135:SEMA3E
gene id: 9135:SEMA3E
uniprot id: A0A8C9N209
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:GGT7
gene id: 9135:GGT7
uniprot id: A0A8C9N9P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

9135:ZDHHC3
gene id: 9135:ZDHHC3
uniprot id: A0A8C9U118
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9135:LOC103812985
gene id: 9135:LOC103812985
uniprot id: A0A8C9L6H6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9135:TPPP
gene id: 9135:TPPP
uniprot id: A0A8C9NP73
names: Similarity
messages: Belongs to the TPPP family.

9135:LOC103822065
gene id: 9135:LOC103822065
uniprot id: A0A8C9MMT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dienelactone hydrolase family.
messages: cytosol

9135:TNFRSF1B
gene id: 9135:TNFRSF1B
uniprot id: A0A8C9MHV5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:TRMU
gene id: 9135:TRMU
uniprot id: A0A8C9MP96
names: Function
names: Similarity
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base.

9135:PICK1
gene id: 9135:PICK1
uniprot id: A0A8C9U6E0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competitive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.
messages: cytoskeleton
messages: perinuclear region
messages: synaptosome

9135:DDX55
gene id: 9135:DDX55
uniprot id: A0A8C9N707
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

9135:NRN1
gene id: 9135:NRN1
uniprot id: A0A8C9KTN1
names: Similarity
messages: Belongs to the neuritin family.

9135:IDH3A
gene id: 9135:IDH3A
uniprot id: A0A8C9UFN5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

9135:RTCB
gene id: 9135:RTCB
uniprot id: A0A8C9MKG1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Catalytic component of the tRNA-splicing ligase complex.
messages: Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
messages: Cytoplasm
messages: Ligation probably proceeds through 3 nucleotidyl transfer steps, with 2',3'-cyclic phosphate termini being hydrolyzed to 3'-P termini in a step that precedes 3'-P activation with GMP. In the first nucleotidyl transfer step, RTCB reacts with GTP to form a covalent RTCB-histidine-GMP intermediate with release of PPi; in the second step, the GMP moiety is transferred to the RNA 3'-P; in the third step, the 5'-OH from the opposite RNA strand attacks the activated 3'-P to form a 3',5'-phosphodiester bond and release GMP.

9135:WARS1
gene id: 9135:WARS1
uniprot id: A0A8C9MXH7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9135:ADORA2A
gene id: 9135:ADORA2A
uniprot id: A0A8C9MJH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

9135:DNASE2B
gene id: 9135:DNASE2B
uniprot id: A0A8C9NM41
names: Similarity
messages: Belongs to the DNase II family.

9135:DDX59
gene id: 9135:DDX59
uniprot id: A0A8C9NAZ8
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX59 subfamily.

9135:NDE1
gene id: 9135:NDE1
uniprot id: A0A8C9N9S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: spindle

9135:CDH12
gene id: 9135:CDH12
uniprot id: A0A8C9MLM1
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

9135:ACER1
gene id: 9135:ACER1
uniprot id: A0A8C9MGL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Membrane

9135:SLC27A6
gene id: 9135:SLC27A6
uniprot id: A0A8C9UFU7
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

9135:LOC103820148
gene id: 9135:LOC103820148
uniprot id: A0A8C9N8A2
names: Subcellular Location Annotation
messages: Membrane

9135:PSMD4
gene id: 9135:PSMD4
uniprot id: A0A8C9MTT3
names: Similarity
messages: Belongs to the proteasome subunit S5A family.

9135:MAP2K3
gene id: 9135:MAP2K3
uniprot id: A0A8C9N4G1
names: Similarity
messages: Belongs to the protein kinase superfamily.

9135:LOC103815242
gene id: 9135:LOC103815242
uniprot id: A0A8C9N0X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

9135:SPARC
gene id: 9135:SPARC
uniprot id: A0A8C9NFC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
messages: Belongs to the SPARC family.
messages: Membrane
messages: basement membrane

9135:SPIN1
gene id: 9135:SPIN1
uniprot id: A0A8C9NIV9
names: Similarity
messages: Belongs to the SPIN/STSY family.

9135:ENPP2
gene id: 9135:ENPP2
uniprot id: A0A8C9UAV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
messages: Secreted

9135:STEAP3
gene id: 9135:STEAP3
uniprot id: A0A8C9N8H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

9135:MED27
gene id: 9135:MED27
uniprot id: A0A8C9MKS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 27 family.
messages: Nucleus

9135:MYRF
gene id: 9135:MYRF
uniprot id: A0A8C9N874
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRF family.
messages: Membrane

9135:PATJ
gene id: 9135:PATJ
uniprot id: A0A8C9UAF8
names: Subcellular Location Annotation
messages: tight junction

9135:LOC108964905
gene id: 9135:LOC108964905
uniprot id: A0A8C9MFL9
names: Similarity
messages: Belongs to the serpin family.

9135:PISD
gene id: 9135:PISD
uniprot id: A0A8C9MK04
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.
messages: Mitochondrion inner membrane

9135:EHD3
gene id: 9135:EHD3
uniprot id: A0A8C9NQT3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

9135:TFIP11
gene id: 9135:TFIP11
uniprot id: A0A8C9MR67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFP11/STIP family.
messages: Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events.
messages: Nucleus

9135:SLC4A11
gene id: 9135:SLC4A11
uniprot id: A0A8C9N5L1
uniprot id: A0A8C9N6J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Membrane

9135:LOC103816903
gene id: 9135:LOC103816903
uniprot id: A0A8C9N257
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Homotetramer.

9135:PKD2L1
gene id: 9135:PKD2L1
uniprot id: A0A8C9NW62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Membrane
messages: cilium membrane

9135:CPT2
gene id: 9135:CPT2
uniprot id: A0A8C9MSR8
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

9135:LOC103814353
gene id: 9135:LOC103814353
uniprot id: A0A8C9NGU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

9135:GGT5
gene id: 9135:GGT5
uniprot id: A0A8C9MJS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

9135:LOC103821672
gene id: 9135:LOC103821672
uniprot id: A0A8C9UDU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

9135:SETD6
gene id: 9135:SETD6
uniprot id: A0A8C9MRY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily.
messages: Nucleus
messages: Protein-lysine N-methyltransferase.

9135:CCL20
gene id: 9135:CCL20
uniprot id: A0A8C9MED3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

9135:IL1RAPL2
gene id: 9135:IL1RAPL2
uniprot id: A0A8C9NXW0
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

9135:TPR
gene id: 9135:TPR
uniprot id: A0A8C9N537
names: Similarity
messages: Belongs to the TPR family.

9135:NTS
gene id: 9135:NTS
uniprot id: A0A8C9MZF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurotensin family.
messages: Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.
messages: Secreted
messages: Vesicle
messages: secretory vesicle

9135:N6AMT1
gene id: 9135:N6AMT1
uniprot id: A0A8C9NBV0
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

9135:PRKCE
gene id: 9135:PRKCE
uniprot id: A0A8C9N972
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

9135:LOC103814190
gene id: 9135:LOC103814190
uniprot id: A0A8C9NXP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-microseminoprotein family.
messages: Secreted

9135:SLC41A3
gene id: 9135:SLC41A3
uniprot id: A0A8C9MNJ9
uniprot id: A0A8C9U7F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

9135:METTL4
gene id: 9135:METTL4
uniprot id: A0A8C9N3G2
names: Similarity
messages: Belongs to the MT-A70-like family.

9135:TRMT11
gene id: 9135:TRMT11
uniprot id: A0A8C9NN67
names: Function
messages: Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.

9135:PRKACB
gene id: 9135:PRKACB
uniprot id: A0A8C9UGV3
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.

9135:HOXA9
gene id: 9135:HOXA9
uniprot id: A0A8C9NQN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

9135:LDAH
gene id: 9135:LDAH
uniprot id: A0A8C9NIL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. LDAH family.
messages: Lipid droplet

9135:PDLIM3
gene id: 9135:PDLIM3
uniprot id: A0A8C9N6T9
names: Subcellular Location Annotation
messages: Z line

9135:GABRA1
gene id: 9135:GABRA1
uniprot id: A0A8C9N5U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA1 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9135:LOC103826740
gene id: 9135:LOC103826740
uniprot id: A0A8C9MMI8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:CENPN
gene id: 9135:CENPN
uniprot id: A0A8C9MTJ7
names: Similarity
messages: Belongs to the CENP-N/CHL4 family.

9135:EMSY
gene id: 9135:EMSY
uniprot id: A0A8C9NPH3
uniprot id: A0A8C9UHZ5
names: Subcellular Location Annotation
messages: Nucleus

9135:MFSD10
gene id: 9135:MFSD10
uniprot id: A0A8C9UH67
names: Subcellular Location Annotation
messages: Membrane

9135:LAPTM4B
gene id: 9135:LAPTM4B
uniprot id: A0A8C9ML88
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

9135:CLP1
gene id: 9135:CLP1
uniprot id: A0A8C9N6Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Clp1 family. Clp1 subfamily.
messages: Component of the tRNA splicing endonuclease complex. Component of pre-mRNA cleavage complex II (CF-II).
messages: Nucleus
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; this phosphorylation event is a prerequisite for the subsequent ligation of the two exon halves and the production of a mature tRNA. Component of the pre-mRNA cleavage complex II (CF-II), which seems to be required for mRNA 3'-end formation. Also phosphorylates the 5'-terminus of exogenously introduced short interfering RNAs (siRNAs), which is a necessary prerequisite for their incorporation into the RNA-induced silencing complex (RISC). However, endogenous siRNAs and microRNAs (miRNAs) that are produced by the cleavage of dsRNA precursors by DICER1 already contain a 5'-phosphate group, so this protein may be dispensible for normal RNA-mediated gene silencing.

9135:TUBGCP3
gene id: 9135:TUBGCP3
uniprot id: A0A8C9MMY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

9135:SLC2A12
gene id: 9135:SLC2A12
uniprot id: A0A8C9NAS5
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

9135:MCM6
gene id: 9135:MCM6
uniprot id: A0A8C9N4A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

9135:CHPT1
gene id: 9135:CHPT1
uniprot id: A0A8C9N550
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

9135:GSN
gene id: 9135:GSN
uniprot id: A0A8C9KVY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the villin/gelsolin family.
messages: Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis.
messages: cytoskeleton

9135:LOC103816300
gene id: 9135:LOC103816300
uniprot id: A0A8C9NU53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Membrane

9135:LOC103820494
gene id: 9135:LOC103820494
uniprot id: A0A8C9MXD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

9135:RPL24
gene id: 9135:RPL24
uniprot id: A0A8C9NV69
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

9135:ABCC9
gene id: 9135:ABCC9
uniprot id: A0A8C9N030
uniprot id: A0A8C9N2U6
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with KCNJ11.
messages: Membrane

9135:SYT14
gene id: 9135:SYT14
uniprot id: A0A8C9MU10
names: Similarity
messages: Belongs to the synaptotagmin family.

9135:HGF
gene id: 9135:HGF
uniprot id: A0A8C9N0E3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Dimer of an alpha chain and a beta chain linked by a disulfide bond. Interacts with SRPX2; the interaction increases HGF mitogenic activity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization.

9135:RAD50
gene id: 9135:RAD50
uniprot id: A0A8C9N8N3
names: Similarity
messages: Belongs to the SMC family. RAD50 subfamily.

9135:EMC3
gene id: 9135:EMC3
uniprot id: A0A8C9L4M7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC3 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

9135:HAUS8
gene id: 9135:HAUS8
uniprot id: A0A8C9MK66
names: Similarity
messages: Belongs to the QWRF family.

9135:PARD6B
gene id: 9135:PARD6B
uniprot id: A0A8C9NSH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

9135:PFKP
gene id: 9135:PFKP
uniprot id: A0A8C9MZV1
uniprot id: A0A8C9N1C6
uniprot id: A0A8C9N259
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:PPARD
gene id: 9135:PPARD
uniprot id: A0A8C9NRA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9135:AASDH
gene id: 9135:AASDH
uniprot id: A0A8C9N0X1
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

9135:LOC103814641
gene id: 9135:LOC103814641
uniprot id: A0A8C9NA11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFRB1 by the constitutively active TGFBR2. Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4. The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes. This constitutes the canonical SMAD-dependent TGF-beta signaling cascade. Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways.

9135:LOC103816843
gene id: 9135:LOC103816843
uniprot id: A0A8C9MRF5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9135:DCK
gene id: 9135:DCK
uniprot id: A0A8C9MLK4
names: Similarity
messages: Belongs to the DCK/DGK family.

9135:LOC103813346
gene id: 9135:LOC103813346
uniprot id: A0A8C9MUU4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9135:BMS1
gene id: 9135:BMS1
uniprot id: A0A8C9MHK3
names: Subcellular Location Annotation
messages: nucleolus

9135:PAX2
gene id: 9135:PAX2
uniprot id: A0A8C9NWN2
names: Subcellular Location Annotation
messages: Nucleus

9135:LOC103824250
gene id: 9135:LOC103824250
uniprot id: A0A8C9NUE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9135:LOC103822554
gene id: 9135:LOC103822554
uniprot id: A0A8C9NL53
names: Subcellular Location Annotation
messages: Nucleus

9135:MSTN
gene id: 9135:MSTN
uniprot id: A0A8C9MK78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts specifically as a negative regulator of skeletal muscle growth.
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Secreted

9135:SLC25A44
gene id: 9135:SLC25A44
uniprot id: A0A8C9NH77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9135:PIK3R1
gene id: 9135:PIK3R1
uniprot id: A0A8C9NCI8
uniprot id: A0A8C9UEG6
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

9135:SLC45A4
gene id: 9135:SLC45A4
uniprot id: A0A8C9N1F7
names: Subcellular Location Annotation
messages: Membrane

9135:LOC103823758
gene id: 9135:LOC103823758
uniprot id: A0A8C9NRV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

9135:RHPN1
gene id: 9135:RHPN1
uniprot id: A0A8C9KSW8
names: Similarity
messages: Belongs to the RHPN family.

9135:TRAM1
gene id: 9135:TRAM1
uniprot id: A0A8C9L6F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

9135:LOC103824466
gene id: 9135:LOC103824466
uniprot id: A0A8C9UC84
names: Similarity
messages: Belongs to the globin family.

9135:LOC103827070
gene id: 9135:LOC103827070
uniprot id: A0A8C9N3V5
names: Similarity
messages: Belongs to the intercrine gamma family.

9135:NPM3
gene id: 9135:NPM3
uniprot id: A0A8C9NPB0
names: Similarity
messages: Belongs to the nucleoplasmin family.

9135:FOXN4
gene id: 9135:FOXN4
uniprot id: A0A8C9MTF2
names: Subcellular Location Annotation
messages: Nucleus

9135:FAM3B
gene id: 9135:FAM3B
uniprot id: A0A8C9NBY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

9135:CDK8
gene id: 9135:CDK8
uniprot id: A0A8C9MVF0
names: Similarity
messages: Belongs to the protein kinase superfamily.

9135:FAM110B
gene id: 9135:FAM110B
uniprot id: A0A8C9NET9
names: Similarity
messages: Belongs to the FAM110 family.

9135:METTL6
gene id: 9135:METTL6
uniprot id: A0A8C9L325
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

9135:CFAP298
gene id: 9135:CFAP298
uniprot id: A0A8C9UD45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP298 family.
messages: cilium basal body

9135:CALHM3
gene id: 9135:CALHM3
uniprot id: A0A8C9NVW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

9135:ELP6
gene id: 9135:ELP6
uniprot id: A0A8C9MQJ0
names: Similarity
messages: Belongs to the ELP6 family.

9135:RPRD1A
gene id: 9135:RPRD1A
uniprot id: A0A8C9MQX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0400 (RTT103) family.
messages: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle.
messages: Nucleus

9135:RER1
gene id: 9135:RER1
uniprot id: A0A8C9MDM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RER1 family.
messages: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
messages: Membrane

9135:LOC103817534
gene id: 9135:LOC103817534
uniprot id: A0A8C9L4J5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9135:ABCA5
gene id: 9135:ABCA5
uniprot id: A0A8C9NER7
names: Subcellular Location Annotation
messages: Membrane

9135:TNFAIP1
gene id: 9135:TNFAIP1
uniprot id: A0A8C9NH79
names: Similarity
messages: Belongs to the BACURD family.

9135:RUVBL1
gene id: 9135:RUVBL1
uniprot id: A0A8C9MMQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Dynein axonemal particle
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

9135:RARS2
gene id: 9135:RARS2
uniprot id: A0A8C9MIU7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9135:ZDHHC22
gene id: 9135:ZDHHC22
uniprot id: A0A8C9N6E3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9135:HOXD12
gene id: 9135:HOXD12
uniprot id: A0A8C9UI48
names: Subcellular Location Annotation
messages: Nucleus

9135:MYOZ3
gene id: 9135:MYOZ3
uniprot id: A0A8C9NF01
names: Similarity
messages: Belongs to the myozenin family.

9135:PPARA
gene id: 9135:PPARA
uniprot id: A0A8C9MHX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

9135:PRLR
gene id: 9135:PRLR
uniprot id: A0A8C9MYG5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Membrane
messages: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
messages: The box 1 motif is required for JAK interaction and/or activation.
messages: This is a receptor for the anterior pituitary hormone prolactin.

9135:LITAFD
gene id: 9135:LITAFD
uniprot id: A0A8C9UEN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

9135:LOC103820323
gene id: 9135:LOC103820323
uniprot id: A0A8C9MKN5
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

9135:EPHB6
gene id: 9135:EPHB6
uniprot id: A0A8C9NR02
names: Subcellular Location Annotation
messages: Membrane

9135:DYNC1I2
gene id: 9135:DYNC1I2
uniprot id: A0A8C9NU33
names: Similarity
messages: Belongs to the dynein intermediate chain family.

9135:LOC103821417
gene id: 9135:LOC103821417
uniprot id: A0A8C9MFY9
names: Similarity
messages: Belongs to the centrin family.

9135:LOC103815251
gene id: 9135:LOC103815251
uniprot id: A0A8C9MFM7
names: Similarity
messages: Belongs to the serpin family.

9135:PRR5L
gene id: 9135:PRR5L
uniprot id: A0A8C9MJY5
names: Similarity
messages: Belongs to the PROTOR family.

9135:B3GNT7
gene id: 9135:B3GNT7
uniprot id: A0A8C9NP56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9135:UGGT2
gene id: 9135:UGGT2
uniprot id: A0A8C9UI10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 8 family.
messages: Endoplasmic reticulum lumen

9135:SVBP
gene id: 9135:SVBP
uniprot id: A0A8C9MIV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVBP family.
messages: Secreted
messages: cytoskeleton

9135:TSPAN6
gene id: 9135:TSPAN6
uniprot id: A0A8C9U4B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9135:ADCYAP1R1
gene id: 9135:ADCYAP1R1
uniprot id: A0A8C9MTE5
names: Subcellular Location Annotation
messages: Membrane

9135:LOC103813813
gene id: 9135:LOC103813813
uniprot id: A0A8C9MLJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 6c family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

9135:TBX15
gene id: 9135:TBX15
uniprot id: A0A8C9NAT9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9135:SETD3
gene id: 9135:SETD3
uniprot id: A0A8C9MX19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. SETD3 actin-histidine methyltransferase family.
messages: Cytoplasm

9135:PLD4
gene id: 9135:PLD4
uniprot id: A0A8C9MTY8
names: Similarity
messages: Belongs to the phospholipase D family.

9135:CEP43
gene id: 9135:CEP43
uniprot id: A0A8C9MIE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP43 family.
messages: cilium basal body

9135:C1D
gene id: 9135:C1D
uniprot id: A0A8C9L3W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the C1D family.
messages: Cytoplasm
messages: Monomer and homodimer.
messages: Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA.
messages: nucleolus

9135:LOC103815347
gene id: 9135:LOC103815347
uniprot id: A0A8C9NJD4
names: Similarity
messages: Belongs to the cytochrome P450 family.

9135:LOC103813629
gene id: 9135:LOC103813629
uniprot id: A0A8C9UBC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9135:CA9
gene id: 9135:CA9
uniprot id: A0A8C9MF95
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

9135:ADGRL4
gene id: 9135:ADGRL4
uniprot id: A0A8C9NLX4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9135:TRIO
gene id: 9135:TRIO
uniprot id: A0A8C9MLR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cytoplasm

9135:PTDSS2
gene id: 9135:PTDSS2
uniprot id: A0A8C9UCS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Membrane

9135:UTS2B
gene id: 9135:UTS2B
uniprot id: A0A8C9NQK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urotensin-2 family.
messages: Secreted

9135:RALY
gene id: 9135:RALY
uniprot id: A0A8C9UC59
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

9135:HMGB2
gene id: 9135:HMGB2
uniprot id: A0A8C9N4K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

9135:TERF1
gene id: 9135:TERF1
uniprot id: A0A8C9L6N9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.
messages: Homodimer.
messages: Nucleus

9135:SNX4
gene id: 9135:SNX4
uniprot id: A0A8C9NB84
names: Similarity
messages: Belongs to the sorting nexin family.

9135:ACOD1
gene id: 9135:ACOD1
uniprot id: A0A8C9NRT5
names: Similarity
messages: Belongs to the PrpD family.

9135:SLU7
gene id: 9135:SLU7
uniprot id: A0A8C9N7L5
uniprot id: A0A8C9N9P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLU7 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

9135:LOC103827166
gene id: 9135:LOC103827166
uniprot id: A0A8C9UGR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9135:CHDH
gene id: 9135:CHDH
uniprot id: A0A8C9MFJ5
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

9135:FHIP2A
gene id: 9135:FHIP2A
uniprot id: A0A8C9UGU4
names: Similarity
messages: Belongs to the FHIP family.

9135:IGBP1
gene id: 9135:IGBP1
uniprot id: A0A8C9KVG0
names: Similarity
messages: Belongs to the IGBP1/TAP42 family.

9135:SGCD
gene id: 9135:SGCD
uniprot id: A0A8C9NF48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

9135:PPM1A
gene id: 9135:PPM1A
uniprot id: A0A8C9MQF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

9135:GNG2
gene id: 9135:GNG2
uniprot id: A0A8C9KXW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

9135:CRYZ
gene id: 9135:CRYZ
uniprot id: A0A8C9N159
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

9135:TPM1
gene id: 9135:TPM1
uniprot id: A0A8C9NTQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

9135:CLSTN3
gene id: 9135:CLSTN3
uniprot id: A0A8C9UH98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsyntenin family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Postsynaptic cell membrane

9135:DDIAS
gene id: 9135:DDIAS
uniprot id: A0A8C9MHJ1
names: Similarity
messages: Belongs to the replication factor A protein 1 family.

9135:FGF14
gene id: 9135:FGF14
uniprot id: A0A8C9NV22
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9135:CD81
gene id: 9135:CD81
uniprot id: A0A8C9MMI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9135:RPL3
gene id: 9135:RPL3
uniprot id: A0A8C9MPA1
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

9135:KIF20A
gene id: 9135:KIF20A
uniprot id: A0A8C9MEP9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9135:ATG4C
gene id: 9135:ATG4C
uniprot id: A0A8C9MU55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

9135:SEC11C
gene id: 9135:SEC11C
uniprot id: A0A8C9MHX9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Component of the signal peptidase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane

9135:MAP4K3
gene id: 9135:MAP4K3
uniprot id: A0A8C9NNZ9
uniprot id: A0A8C9NQW4
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

9135:RPS12
gene id: 9135:RPS12
uniprot id: A0A8C9UE30
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

9135:POT1
gene id: 9135:POT1
uniprot id: A0A8C9MJZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the telombin family.
messages: Nucleus
messages: telomere

9135:CWC15
gene id: 9135:CWC15
uniprot id: A0A8C9MK60
names: Similarity
messages: Belongs to the CWC15 family.

9135:MEOX2
gene id: 9135:MEOX2
uniprot id: A0A8C9NJG6
names: Subcellular Location Annotation
messages: Nucleus

9135:PCBP4
gene id: 9135:PCBP4
uniprot id: A0A8C9NXY6
names: Subcellular Location Annotation
messages: Cytoplasm

9135:CHMP4B
gene id: 9135:CHMP4B
uniprot id: A0A8C9MYR0
names: Similarity
messages: Belongs to the SNF7 family.

9135:HPGD
gene id: 9135:HPGD
uniprot id: A0A8C9UDJ0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9135:ATRX
gene id: 9135:ATRX
uniprot id: A0A8C9NUN0
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

9135:MYD88
gene id: 9135:MYD88
uniprot id: A0A8C9MV60
names: Function
names: Subcellular Location Annotation
messages: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
messages: Cytoplasm

9135:ITIH2
gene id: 9135:ITIH2
uniprot id: A0A8C9N603
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

9135:ELAVL1
gene id: 9135:ELAVL1
uniprot id: A0A8C9KVV2
uniprot id: A0A8C9L201
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM elav family.
messages: Cytoplasm

9135:PLIN1
gene id: 9135:PLIN1
uniprot id: A0A8C9UA46
names: Similarity
messages: Belongs to the perilipin family.

9135:PDK1
gene id: 9135:PDK1
uniprot id: A0A8C9NQX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

9135:LOC103813914
gene id: 9135:LOC103813914
uniprot id: A0A8C9UI51
names: Similarity
messages: Belongs to the cytochrome P450 family.

9135:RPL35A
gene id: 9135:RPL35A
uniprot id: A0A8C9NNS1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

9135:TBC1D23
gene id: 9135:TBC1D23
uniprot id: A0A8C9NTQ0
names: Subcellular Location Annotation
messages: trans-Golgi network

9135:LCLAT1
gene id: 9135:LCLAT1
uniprot id: A0A8C9UH43
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

9135:OTX2
gene id: 9135:OTX2
uniprot id: A0A8C9MQK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

9135:LOC103815509
gene id: 9135:LOC103815509
uniprot id: A0A8C9UCG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9135:TMEM208
gene id: 9135:TMEM208
uniprot id: A0A8C9U9B9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM208 family.
messages: Endoplasmic reticulum membrane
messages: May function as a negative regulator of endoplasmic reticulum-stress induced autophagy.
messages: Membrane

9135:ENTPD6
gene id: 9135:ENTPD6
uniprot id: A0A8C9NLV0
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

9135:ABCB11
gene id: 9135:ABCB11
uniprot id: A0A8C9NT72
names: Subcellular Location Annotation
messages: Membrane

9135:PPFIA1
gene id: 9135:PPFIA1
uniprot id: A0A8C9MYN4
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

9135:TSC22D1
gene id: 9135:TSC22D1
uniprot id: A0A8C9NLF9
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

9135:STYXL2
gene id: 9135:STYXL2
uniprot id: A0A8C9NFP7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

9135:GGH
gene id: 9135:GGH
uniprot id: A0A8C9NKA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C26 family.
messages: extracellular space

9135:MAPK6
gene id: 9135:MAPK6
uniprot id: A0A8C9MNN5
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

9135:TIPRL
gene id: 9135:TIPRL
uniprot id: A0A8C9N2P4
names: Similarity
messages: Belongs to the TIP41 family.

9135:ECHDC1
gene id: 9135:ECHDC1
uniprot id: A0A8C9NLM1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

9135:WAPL
gene id: 9135:WAPL
uniprot id: A0A8C9MJC2
uniprot id: A0A8C9MJQ5
names: Similarity
messages: Belongs to the WAPL family.

9135:TUBE1
gene id: 9135:TUBE1
uniprot id: A0A8C9NPT9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: cytoskeleton

9135:MEF2C
gene id: 9135:MEF2C
uniprot id: A0A8C9UC42
names: Subcellular Location Annotation
messages: Nucleus

9135:TIE1
gene id: 9135:TIE1
uniprot id: A0A8C9L222
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9135:LOC103817691
gene id: 9135:LOC103817691
uniprot id: A0A8C9N9R6
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

9135:CREBL2
gene id: 9135:CREBL2
uniprot id: A0A8C9N953
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Nucleus

9135:FAM83A
gene id: 9135:FAM83A
uniprot id: A0A8C9MVG6
names: Similarity
messages: Belongs to the FAM83 family.

9135:GPBP1
gene id: 9135:GPBP1
uniprot id: A0A8C9N1W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vasculin family.
messages: Nucleus

9135:ENAH
gene id: 9135:ENAH
uniprot id: A0A8C9NK56
uniprot id: A0A8C9NP52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ena/VASP family.
messages: cytoskeleton

9135:AARS1
gene id: 9135:AARS1
uniprot id: A0A8C9MSB6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Monomer. Interacts with ANKRD16; the interaction is direct.

9135:LOC103826392
gene id: 9135:LOC103826392
uniprot id: A0A8C9KTU8
names: Function
messages: Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.

9135:DGLUCY
gene id: 9135:DGLUCY
uniprot id: A0A8C9N0Y5
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

9135:PPM1G
gene id: 9135:PPM1G
uniprot id: A0A8C9NJH8
names: Similarity
messages: Belongs to the PP2C family.

9135:ITGB6
gene id: 9135:ITGB6
uniprot id: A0A8C9UGK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

9135:SERPINH1
gene id: 9135:SERPINH1
uniprot id: A0A8C9L0M9
names: Function
names: Similarity
messages: Belongs to the serpin family.
messages: Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.

9135:NDUFA5
gene id: 9135:NDUFA5
uniprot id: A0A8C9U6K3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA5 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9135:RAB33A
gene id: 9135:RAB33A
uniprot id: A0A8C9NRS0
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

9135:PTCD3
gene id: 9135:PTCD3
uniprot id: A0A8C9NN64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS39 family.
messages: Mitochondrion

9135:RIPOR3
gene id: 9135:RIPOR3
uniprot id: A0A8C9NRK7
names: Similarity
messages: Belongs to the RIPOR family.

9135:MFF
gene id: 9135:MFF
uniprot id: A0A8C9KSM7
uniprot id: A0A8C9KX45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tango11 family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Peroxisome
messages: Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface.

9135:PRKD1
gene id: 9135:PRKD1
uniprot id: A0A8C9NDH3
uniprot id: A0A8C9UED1
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by DAG and phorbol esters.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Cytoplasm
messages: Membrane

9135:PALMD
gene id: 9135:PALMD
uniprot id: A0A8C9NDB5
names: Similarity
messages: Belongs to the paralemmin family.

9135:FHIP1A
gene id: 9135:FHIP1A
uniprot id: A0A8C9NEL7
names: Similarity
messages: Belongs to the FHIP family.

9135:NR2F2
gene id: 9135:NR2F2
uniprot id: A0A8C9N036
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9135:EREG
gene id: 9135:EREG
uniprot id: A0A8C9U8Q9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:SFRP5
gene id: 9135:SFRP5
uniprot id: A0A8C9NTK1
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:FAM98A
gene id: 9135:FAM98A
uniprot id: A0A8C9NA60
names: Similarity
messages: Belongs to the FAM98 family.

9135:LOC108962703
gene id: 9135:LOC108962703
uniprot id: A0A8C9UAC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

9135:LOC103821612
gene id: 9135:LOC103821612
uniprot id: A0A8C9UCB3
names: Similarity
messages: Belongs to the intermediate filament family.

9135:SKI
gene id: 9135:SKI
uniprot id: A0A8C9L4Q5
names: Similarity
messages: Belongs to the SKI family.

9135:PKIB
gene id: 9135:PKIB
uniprot id: A0A8C9NJE4
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

9135:LNPK
gene id: 9135:LNPK
uniprot id: A0A8C9NUE2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Homodimer; homodimerization requires the C4-type zinc finger motif and decreases during mitosis in a phosphorylation-dependent manner.
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

9135:LOC103815947
gene id: 9135:LOC103815947
uniprot id: A0A8C9NVN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DUOXA family.
messages: Membrane

9135:EIF4A2
gene id: 9135:EIF4A2
uniprot id: A0A8C9NJI5
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

9135:BTBD10
gene id: 9135:BTBD10
uniprot id: A0A8C9NY07
names: Subcellular Location Annotation
messages: Cytoplasm

9135:LOC103814509
gene id: 9135:LOC103814509
uniprot id: A0A8C9U3X9
names: Similarity
messages: Belongs to the peptidase C14A family.

9135:CAMLG
gene id: 9135:CAMLG
uniprot id: A0A8C9N7Q8
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET1/WRB, acts as a membrane receptor for soluble GET3/TRC40, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. Required for the stability of GET1. Stimulates calcium signaling in T cells through its involvement in elevation of intracellular calcium. Essential for the survival of peripheral follicular B cells.

9135:PGM5
gene id: 9135:PGM5
uniprot id: A0A8C9U684
names: Similarity
messages: Belongs to the phosphohexose mutase family.

9135:ADRB2
gene id: 9135:ADRB2
uniprot id: A0A8C9MF16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Golgi apparatus
messages: Membrane

9135:SEC24C
gene id: 9135:SEC24C
uniprot id: A0A8C9L3U8
uniprot id: A0A8C9MEP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

9135:RTN4
gene id: 9135:RTN4
uniprot id: A0A8C9NJQ8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9135:WSCD1
gene id: 9135:WSCD1
uniprot id: A0A8C9NH73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WSCD family.
messages: Golgi apparatus membrane
messages: Sialate:O-sulfotransferase which catalyzes 8-O-sulfation at the Sia-glycan level using 3'-phosphoadenosine 5'-phosphosulfate (PAPS) as a donor, forming 8-O-sulfated Sia (Sia8S)-glycans.

9135:LOC103816970
gene id: 9135:LOC103816970
uniprot id: A0A8C9KRJ6
uniprot id: A0A8C9KRL6
uniprot id: A0A8C9KS97
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

9135:SLC25A36
gene id: 9135:SLC25A36
uniprot id: A0A8C9MHZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9135:ARF1
gene id: 9135:ARF1
uniprot id: A0A8C9MTC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

9135:TMEM234
gene id: 9135:TMEM234
uniprot id: A0A8C9MNH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM234 family.
messages: Membrane

9135:DBT
gene id: 9135:DBT
uniprot id: A0A8C9ND05
uniprot id: A0A8C9NGR5
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

9135:CCR10
gene id: 9135:CCR10
uniprot id: A0A8C9MVD7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9135:G6PC2
gene id: 9135:G6PC2
uniprot id: A0A8C9UHT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

9135:FAR1
gene id: 9135:FAR1
uniprot id: A0A8C9N1H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acyl-CoA reductase family.
messages: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
messages: Peroxisome membrane

9135:UNC13B
gene id: 9135:UNC13B
uniprot id: A0A8C9MI51
names: Subcellular Location Annotation
messages: Cytoplasm

9135:RHBG
gene id: 9135:RHBG
uniprot id: A0A8C9NNK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

9135:C3H6orf120
gene id: 9135:C3H6orf120
uniprot id: A0A8C9MIT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0669 family.
messages: Secreted

9135:CCT5
gene id: 9135:CCT5
uniprot id: A0A8C9MMU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

9135:NR5A2
gene id: 9135:NR5A2
uniprot id: A0A8C9NCH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR5 subfamily.
messages: Nucleus

9135:BEND6
gene id: 9135:BEND6
uniprot id: A0A8C9N304
uniprot id: A0A8C9UD39
names: Subcellular Location Annotation
messages: Nucleus

9135:WNT5A
gene id: 9135:WNT5A
uniprot id: A0A8C9MFT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9135:APOLD1
gene id: 9135:APOLD1
uniprot id: A0A8C9MV63
names: Similarity
messages: Belongs to the apolipoprotein L family.

9135:CDC5L
gene id: 9135:CDC5L
uniprot id: A0A8C9NMX3
names: Similarity
messages: Belongs to the CEF1 family.

9135:GJC2
gene id: 9135:GJC2
uniprot id: A0A8C9MT24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9135:DERL2
gene id: 9135:DERL2
uniprot id: A0A8C9MRY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Membrane

9135:HAPLN3
gene id: 9135:HAPLN3
uniprot id: A0A8C9MS27
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:RNF121
gene id: 9135:RNF121
uniprot id: A0A8C9UII7
names: Subcellular Location Annotation
messages: Membrane

9135:SEC16B
gene id: 9135:SEC16B
uniprot id: A0A8C9N5G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC16 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.
messages: SEC16A and SEC16B are each present in multiple copies in a heteromeric complex.

9135:PUS10
gene id: 9135:PUS10
uniprot id: A0A8C9NMU9
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.

9135:MOGAT1
gene id: 9135:MOGAT1
uniprot id: A0A8C9MGU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane

9135:LYN
gene id: 9135:LYN
uniprot id: A0A8C9NIC3
uniprot id: A0A8C9UFD3
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

9135:BICD2
gene id: 9135:BICD2
uniprot id: A0A8C9N7H8
uniprot id: A0A8C9NA65
names: Similarity
messages: Belongs to the BicD family.

9135:LOC103813332
gene id: 9135:LOC103813332
uniprot id: A0A8C9MUQ2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9135:ADCYAP1
gene id: 9135:ADCYAP1
uniprot id: A0A8C9N628
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

9135:LUC7L2
gene id: 9135:LUC7L2
uniprot id: A0A8C9MSF7
names: Similarity
messages: Belongs to the Luc7 family.

9135:MELK
gene id: 9135:MELK
uniprot id: A0A8C9UDI9
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

9135:VBP1
gene id: 9135:VBP1
uniprot id: A0A8C9NWQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit alpha family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

9135:DYNLT1
gene id: 9135:DYNLT1
uniprot id: A0A8C9NJ88
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

9135:GPATCH1
gene id: 9135:GPATCH1
uniprot id: A0A8C9UF73
names: Similarity
messages: Belongs to the GPATCH1 family.

9135:TEKT4
gene id: 9135:TEKT4
uniprot id: A0A8C9MTB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

9135:RPL36
gene id: 9135:RPL36
uniprot id: A0A8C9KVF9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

9135:MVD
gene id: 9135:MVD
uniprot id: A0A8C9MVG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diphosphomevalonate decarboxylase family.
messages: Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis.
messages: Nucleus

9135:PNN
gene id: 9135:PNN
uniprot id: A0A8C9N811
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pinin family.
messages: Found in a mRNA splicing-dependent exon junction complex (EJC). Found in a complex with SR proteins. Found in a mRNP complex with RNPS1. Component of the PSAP complex consisting of RNPS1, SAP18 and PNN. Interacts with PNISR, CTBP1, CTBP2, KRT8, KRT18, KRT19, PS1D/PNO40, PPIG, RNPS1, SFRS4 and SRRM2. Identified in the spliceosome C complex.
messages: Nucleus speckle
messages: desmosome

9135:SVIL
gene id: 9135:SVIL
uniprot id: A0A8C9N1X6
uniprot id: A0A8C9N220
uniprot id: A0A8C9N2G2
uniprot id: A0A8C9N362
uniprot id: A0A8C9N3T0
names: Similarity
messages: Belongs to the villin/gelsolin family.

9135:CANX
gene id: 9135:CANX
uniprot id: A0A8C9NCQ1
names: Similarity
messages: Belongs to the calreticulin family.

9135:AGPAT2
gene id: 9135:AGPAT2
uniprot id: A0A8C9U457
names: Domain
names: Function
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

9135:CCR6
gene id: 9135:CCR6
uniprot id: A0A8C9MI56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

9135:FGF7
gene id: 9135:FGF7
uniprot id: A0A8C9MPQ0
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9135:ADORA3
gene id: 9135:ADORA3
uniprot id: A0A8C9NSI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

9135:ETS1
gene id: 9135:ETS1
uniprot id: A0A8C9NZ15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Cytoplasm
messages: Nucleus

9135:BROX
gene id: 9135:BROX
uniprot id: A0A8C9MY31
names: Similarity
messages: Belongs to the BROX family.

9135:ACAT1
gene id: 9135:ACAT1
uniprot id: A0A8C9MNP3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

9135:LOC103814008
gene id: 9135:LOC103814008
uniprot id: A0A8C9MGQ4
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

9135:WNT3A
gene id: 9135:WNT3A
uniprot id: A0A8C9MTH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9135:DPP4
gene id: 9135:DPP4
uniprot id: A0A8C9NIB6
uniprot id: A0A8C9NNI7
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the peptidase S9B family. DPPIV subfamily.
messages: Cell junction
messages: Cell membrane
messages: Membrane raft
messages: invadopodium membrane
messages: lamellipodium membrane

9135:NUP210
gene id: 9135:NUP210
uniprot id: A0A8C9UED6
names: Similarity
messages: Belongs to the NUP210 family.

9135:LOC103821605
gene id: 9135:LOC103821605
uniprot id: A0A8C9MYP5
names: Similarity
messages: Belongs to the intermediate filament family.

9135:SLC25A20
gene id: 9135:SLC25A20
uniprot id: A0A8C9MSU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9135:LOC103820042
gene id: 9135:LOC103820042
uniprot id: A0A8C9MLU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the claudin family.
messages: Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN1 and CLDN2 homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9135:ASPA
gene id: 9135:ASPA
uniprot id: A0A8C9N8N0
names: Cofactor
names: Similarity
messages: Belongs to the AspA/AstE family. Aspartoacylase subfamily.
messages: Binds 1 zinc ion per subunit.

9135:HACL1
gene id: 9135:HACL1
uniprot id: A0A8C9NPW7
names: Similarity
messages: Belongs to the TPP enzyme family.

9135:ARRDC3
gene id: 9135:ARRDC3
uniprot id: A0A8C9MWG6
names: Similarity
messages: Belongs to the arrestin family.

9135:F3
gene id: 9135:F3
uniprot id: A0A8C9NFG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tissue factor family.
messages: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
messages: Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII.

9135:BICC1
gene id: 9135:BICC1
uniprot id: A0A8C9MJU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BicC family.
messages: Cytoplasm

9135:ATP12A
gene id: 9135:ATP12A
uniprot id: A0A8C9UDY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane

9135:SEC22A
gene id: 9135:SEC22A
uniprot id: A0A8C9NEJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in vesicle transport between the ER and the Golgi complex.
messages: Membrane

9135:AMDHD1
gene id: 9135:AMDHD1
uniprot id: A0A8C9UBW9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.

9135:EP300
gene id: 9135:EP300
uniprot id: A0A8C9MQK9
names: Subcellular Location Annotation
messages: Cytoplasm

9135:NUDT2
gene id: 9135:NUDT2
uniprot id: A0A8C9NV15
names: Similarity
messages: Belongs to the Nudix hydrolase family.

9135:MUSTN1
gene id: 9135:MUSTN1
uniprot id: A0A8C9KSS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MUSTANG family.
messages: Nucleus

9135:ALG12
gene id: 9135:ALG12
uniprot id: A0A8C9MLP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9135:IAH1
gene id: 9135:IAH1
uniprot id: A0A8C9NCQ8
names: Function
names: Similarity
messages: Belongs to the 'GDSL' lipolytic enzyme family. IAH1 subfamily.
messages: Probable lipase.

9135:LOC103824904
gene id: 9135:LOC103824904
uniprot id: A0A8C9U7P6
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

9135:AGT
gene id: 9135:AGT
uniprot id: A0A8C9MIZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the serpin family.
messages: Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis.
messages: Secreted
messages: Stimulates aldosterone release.

9135:CHL1
gene id: 9135:CHL1
uniprot id: A0A8C9N1L1
names: Similarity
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.

9135:OPN5
gene id: 9135:OPN5
uniprot id: A0A8C9NLY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

9135:XRCC3
gene id: 9135:XRCC3
uniprot id: A0A8C9MTC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Cytoplasm
messages: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions.
messages: Nucleus

9135:MTFR2
gene id: 9135:MTFR2
uniprot id: A0A8C9MH45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

9135:SLC37A3
gene id: 9135:SLC37A3
uniprot id: A0A8C9N6X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

9135:HGFAC
gene id: 9135:HGFAC
uniprot id: A0A8C9UH79
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:LOC103826777
gene id: 9135:LOC103826777
uniprot id: A0A8C9MPT6
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

9135:HSPB1
gene id: 9135:HSPB1
uniprot id: A0A8C9MS11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: spindle

9135:IRF2
gene id: 9135:IRF2
uniprot id: A0A8C9N678
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Nucleus

9135:FAM76A
gene id: 9135:FAM76A
uniprot id: A0A8C9UCH4
names: Similarity
messages: Belongs to the FAM76 family.

9135:PCMTD1
gene id: 9135:PCMTD1
uniprot id: A0A8C9NI91
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

9135:LOC103821606
gene id: 9135:LOC103821606
uniprot id: A0A8C9MY88
names: Similarity
messages: Belongs to the intermediate filament family.

9135:PKN3
gene id: 9135:PKN3
uniprot id: A0A8C9MP50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Nucleus

9135:SCAMP1
gene id: 9135:SCAMP1
uniprot id: A0A8C9MTC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

9135:ADGRG2
gene id: 9135:ADGRG2
uniprot id: A0A8C9NIR4
names: Subcellular Location Annotation
messages: Membrane

9135:ATP1B4
gene id: 9135:ATP1B4
uniprot id: A0A8C9NQM1
uniprot id: A0A8C9UI79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

9135:LOC103818805
gene id: 9135:LOC103818805
uniprot id: A0A8C9NGR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

9135:ZCCHC8
gene id: 9135:ZCCHC8
uniprot id: A0A8C9N4Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZCCHC8 family.
messages: nucleoplasm

9135:XYLT2
gene id: 9135:XYLT2
uniprot id: A0A8C9KVQ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 14 family. XylT subfamily.
messages: Golgi apparatus membrane
messages: Membrane
messages: Monomer.

9135:A1CF
gene id: 9135:A1CF
uniprot id: A0A8C9MKI1
names: Subcellular Location Annotation
messages: Cytoplasm

9135:CIT
gene id: 9135:CIT
uniprot id: A0A8C9U7N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cytoplasm
messages: Plays a role in cytokinesis. Displays serine/threonine protein kinase activity.

9135:HEPHL1
gene id: 9135:HEPHL1
uniprot id: A0A8C9U6E4
names: Similarity
messages: Belongs to the multicopper oxidase family.

9135:NQO2
gene id: 9135:NQO2
uniprot id: A0A8C9KZ87
names: Similarity
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family.

9135:LOC103820662
gene id: 9135:LOC103820662
uniprot id: A0A8C9NRH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNF-like-inhibitor family.
messages: Secreted

9135:TMEM35A
gene id: 9135:TMEM35A
uniprot id: A0A8C9UI88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

9135:ST6GALNAC1
gene id: 9135:ST6GALNAC1
uniprot id: A0A8C9MIL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9135:CAMSAP2
gene id: 9135:CAMSAP2
uniprot id: A0A8C9NC42
uniprot id: A0A8C9UEM0
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

9135:ZNF330
gene id: 9135:ZNF330
uniprot id: A0A8C9NFN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOA36 family.
messages: nucleolus

9135:CERS5
gene id: 9135:CERS5
uniprot id: A0A8C9UCQ6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

9135:DPH2
gene id: 9135:DPH2
uniprot id: A0A8C9L2K1
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family. DPH2 subfamily.
messages: Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase. Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit.

9135:CCNE1
gene id: 9135:CCNE1
uniprot id: A0A8C9MKV3
names: Similarity
messages: Belongs to the cyclin family.

9135:IP6K1
gene id: 9135:IP6K1
uniprot id: A0A8C9NE70
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

9135:HNRNPAB
gene id: 9135:HNRNPAB
uniprot id: A0A8C9N9X5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9135:ANAPC13
gene id: 9135:ANAPC13
uniprot id: A0A8C9U8J3
names: Function
names: Similarity
messages: Belongs to the APC13 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

9135:SLC46A2
gene id: 9135:SLC46A2
uniprot id: A0A8C9MHB2
names: Subcellular Location Annotation
messages: Membrane

9135:RTEL1
gene id: 9135:RTEL1
uniprot id: A0A8C9NK01
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by counteracting telomeric G4-DNA structures, which together ensure the dynamics and stability of the telomere.
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9135:SEMA3C
gene id: 9135:SEMA3C
uniprot id: A0A8C9UD20
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9135:EAF1
gene id: 9135:EAF1
uniprot id: A0A8C9MF24
names: Similarity
messages: Belongs to the EAF family.

9135:ATP6V1G3
gene id: 9135:ATP6V1G3
uniprot id: A0A8C9NBV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

9135:SEMA3D
gene id: 9135:SEMA3D
uniprot id: A0A8C9N0N3
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:PHF20
gene id: 9135:PHF20
uniprot id: A0A8C9UFC6
names: Subcellular Location Annotation
messages: Nucleus

9135:ESR2
gene id: 9135:ESR2
uniprot id: A0A8C9MSM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

9135:PWWP3A
gene id: 9135:PWWP3A
uniprot id: A0A8C9MU65
names: Similarity
messages: Belongs to the PWWP3A family.

9135:AQP5
gene id: 9135:AQP5
uniprot id: A0A8C9MZL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

9135:LOC103813172
gene id: 9135:LOC103813172
uniprot id: A0A8C9U1N0
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

9135:RHPN2
gene id: 9135:RHPN2
uniprot id: A0A8C9NBC8
names: Similarity
messages: Belongs to the RHPN family.

9135:LOC103814104
gene id: 9135:LOC103814104
uniprot id: A0A8C9UFW6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:TACSTD2
gene id: 9135:TACSTD2
uniprot id: A0A8C9MTF4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPCAM family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9135:JUP
gene id: 9135:JUP
uniprot id: A0A8C9MX21
names: Similarity
messages: Belongs to the beta-catenin family.

9135:RGS5
gene id: 9135:RGS5
uniprot id: A0A8C9NWX2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha.

9135:KDM3A
gene id: 9135:KDM3A
uniprot id: A0A8C9UGR2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM2 histone demethylase family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code.
messages: Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors.
messages: Nucleus
messages: The JmjC domain and the C6-type zinc-finger are required for the demethylation activity.

9135:GLB1L
gene id: 9135:GLB1L
uniprot id: A0A8C9NH91
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

9135:LOC103824943
gene id: 9135:LOC103824943
uniprot id: A0A8C9MQV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

9135:SLC25A13
gene id: 9135:SLC25A13
uniprot id: A0A8C9NGX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

9135:MTFR1
gene id: 9135:MTFR1
uniprot id: A0A8C9NI83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

9135:KIF24
gene id: 9135:KIF24
uniprot id: A0A8C9NNT9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9135:SMPDL3B
gene id: 9135:SMPDL3B
uniprot id: A0A8C9NLU5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) per subunit.
messages: Secreted

9135:SLC16A6
gene id: 9135:SLC16A6
uniprot id: A0A8C9UFY4
names: Subcellular Location Annotation
messages: Membrane

9135:NT5DC1
gene id: 9135:NT5DC1
uniprot id: A0A8C9NLD3
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

9135:HSD3B7
gene id: 9135:HSD3B7
uniprot id: A0A8C9MRL7
names: Similarity
messages: Belongs to the 3-beta-HSD family.

9135:DRAM1
gene id: 9135:DRAM1
uniprot id: A0A8C9N581
names: Subcellular Location Annotation
messages: Membrane

9135:IL12B
gene id: 9135:IL12B
uniprot id: A0A8C9L686
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-12B family.
messages: Heterodimer with IL12A; disulfide-linked. The heterodimer is known as interleukin IL-12.
messages: Secreted

9135:LOC103814987
gene id: 9135:LOC103814987
uniprot id: A0A8C9MF45
names: Similarity
messages: Belongs to the folate receptor family.

9135:SUPT3H
gene id: 9135:SUPT3H
uniprot id: A0A8C9NJ69
uniprot id: A0A8C9UGB5
names: Subcellular Location Annotation
messages: Nucleus

9135:SNU13
gene id: 9135:SNU13
uniprot id: A0A8C9MR80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

9135:LOC103820060
gene id: 9135:LOC103820060
uniprot id: A0A8C9N833
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

9135:MON1A
gene id: 9135:MON1A
uniprot id: A0A8C9KSP8
names: Function
names: Similarity
messages: Belongs to the MON1/SAND family.
messages: Plays an important role in membrane trafficking through the secretory apparatus.

9135:SNCG
gene id: 9135:SNCG
uniprot id: A0A8C9MJC7
names: Similarity
names: Subunit
messages: Belongs to the synuclein family.
messages: May be a centrosome-associated protein. Interacts with MYOC; affects its secretion and its aggregation.

9135:PYROXD1
gene id: 9135:PYROXD1
uniprot id: A0A8C9MW07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. PYROXD1 subfamily.
messages: sarcomere

9135:PIP4P2
gene id: 9135:PIP4P2
uniprot id: A0A8C9MH93
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

9135:BRINP1
gene id: 9135:BRINP1
uniprot id: A0A8C9MVE7
names: Similarity
messages: Belongs to the BRINP family.

9135:SAMD8
gene id: 9135:SAMD8
uniprot id: A0A8C9MGN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

9135:RSPO4
gene id: 9135:RSPO4
uniprot id: A0A8C9NJR6
names: Similarity
messages: Belongs to the R-spondin family.

9135:ATP11A
gene id: 9135:ATP11A
uniprot id: A0A8C9MN50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

9135:LOC103821977
gene id: 9135:LOC103821977
uniprot id: A0A8C9KXK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

9135:MAN1A2
gene id: 9135:MAN1A2
uniprot id: A0A8C9UEW5
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

9135:FBXO9
gene id: 9135:FBXO9
uniprot id: A0A8C9ND79
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complex SCF(FBXO9).
messages: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins and acts as a regulator of mTOR signaling.

9135:RNF7
gene id: 9135:RNF7
uniprot id: A0A8C9KSA7
names: Similarity
messages: Belongs to the RING-box family.

9135:FLNB
gene id: 9135:FLNB
uniprot id: A0A8C9MKY8
uniprot id: A0A8C9ML50
uniprot id: A0A8C9ML60
names: Similarity
messages: Belongs to the filamin family.

9135:BRS3
gene id: 9135:BRS3
uniprot id: A0A8C9MKE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9135:LOC103815382
gene id: 9135:LOC103815382
uniprot id: A0A8C9UHC1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer. Isoform composition of the tetramer may determine transactivation activity.
messages: Nucleus

9135:SMC3
gene id: 9135:SMC3
uniprot id: A0A8C9NT98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC3 subfamily.
messages: Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex also plays an important role in spindle pole assembly during mitosis and in chromosomes movement.
messages: Nucleus
messages: centromere

9135:GPR83
gene id: 9135:GPR83
uniprot id: A0A8C9MJZ5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9135:MXRA8
gene id: 9135:MXRA8
uniprot id: A0A8C9NWI7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9135:PFDN4
gene id: 9135:PFDN4
uniprot id: A0A8C9MED5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

9135:OSBPL8
gene id: 9135:OSBPL8
uniprot id: A0A8C9N340
names: Similarity
messages: Belongs to the OSBP family.

9135:MATK
gene id: 9135:MATK
uniprot id: A0A8C9L2S1
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

9135:LOC103815508
gene id: 9135:LOC103815508
uniprot id: A0A8C9MZR4
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

9135:SHH
gene id: 9135:SHH
uniprot id: A0A8C9MXY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

9135:DCLRE1B
gene id: 9135:DCLRE1B
uniprot id: A0A8C9UHC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

9135:SLC25A25
gene id: 9135:SLC25A25
uniprot id: A0A8C9MV01
uniprot id: A0A8C9MVQ8
uniprot id: A0A8C9UBF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

9135:CMTM8
gene id: 9135:CMTM8
uniprot id: A0A8C9MEU5
names: Subcellular Location Annotation
messages: Membrane

9135:NEMF
gene id: 9135:NEMF
uniprot id: A0A8C9MEY0
names: Similarity
messages: Belongs to the NEMF family.

9135:CCN4
gene id: 9135:CCN4
uniprot id: A0A8C9UCU1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9135:PHACTR3
gene id: 9135:PHACTR3
uniprot id: A0A8C9NRZ1
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

9135:LOC103820087
gene id: 9135:LOC103820087
uniprot id: A0A8C9MTK8
uniprot id: A0A8C9MVF8
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

9135:TDP2
gene id: 9135:TDP2
uniprot id: A0A8C9MXN1
names: Subcellular Location Annotation
messages: PML body

9135:TPX2
gene id: 9135:TPX2
uniprot id: A0A8C9NKX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPX2 family.
messages: Nucleus
messages: spindle pole

9135:PSAT1
gene id: 9135:PSAT1
uniprot id: A0A8C9NM02
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.

9135:CEP63
gene id: 9135:CEP63
uniprot id: A0A8C9MRI3
uniprot id: A0A8C9U8J7
names: Similarity
messages: Belongs to the CEP63 family.

9135:UBE2C
gene id: 9135:UBE2C
uniprot id: A0A8C9NMJ4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9135:SYK
gene id: 9135:SYK
uniprot id: A0A8C9NKA2
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.

9135:SLC29A3
gene id: 9135:SLC29A3
uniprot id: A0A8C9NUB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

9135:LOC103816299
gene id: 9135:LOC103816299
uniprot id: A0A8C9NT84
names: Similarity
messages: Belongs to the EVA1 family.

9135:LOC103824215
gene id: 9135:LOC103824215
uniprot id: A0A8C9UIQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

9135:GPX7
gene id: 9135:GPX7
uniprot id: A0A8C9MS69
names: Similarity
messages: Belongs to the glutathione peroxidase family.

9135:ARMC1
gene id: 9135:ARMC1
uniprot id: A0A8C9NJN8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.
messages: Membrane
messages: Mitochondrion outer membrane

9135:CLCN4
gene id: 9135:CLCN4
uniprot id: A0A8C9NHG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

9135:PTBP1
gene id: 9135:PTBP1
uniprot id: A0A8C9MRE8
names: Subcellular Location Annotation
messages: Nucleus

9135:PIGS
gene id: 9135:PIGS
uniprot id: A0A8C9MVC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGS family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9135:BCAR1
gene id: 9135:BCAR1
uniprot id: A0A8C9MQX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

9135:SYT1
gene id: 9135:SYT1
uniprot id: A0A8C9MZR9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: synaptic vesicle membrane

9135:LOC103819192
gene id: 9135:LOC103819192
uniprot id: A0A8C9NAA0
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

9135:PITPNM1
gene id: 9135:PITPNM1
uniprot id: A0A8C9N7B8
names: Similarity
messages: Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.

9135:ZC3H12B
gene id: 9135:ZC3H12B
uniprot id: A0A8C9NS10
names: Similarity
messages: Belongs to the ZC3H12 family.

9135:CSAD
gene id: 9135:CSAD
uniprot id: A0A8C9N230
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

9135:PARPBP
gene id: 9135:PARPBP
uniprot id: A0A8C9N645
uniprot id: A0A8C9N9I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PARI family.
messages: Cytoplasm
messages: Nucleus

9135:GABARAPL2
gene id: 9135:GABARAPL2
uniprot id: A0A8C9N8P0
names: Similarity
messages: Belongs to the ATG8 family.

9135:ZNF532
gene id: 9135:ZNF532
uniprot id: A0A8C9MHV6
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

9135:PIK3CB
gene id: 9135:PIK3CB
uniprot id: A0A8C9NWD2
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

9135:KCNA4
gene id: 9135:KCNA4
uniprot id: A0A8C9MZW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.4/KCNA4 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: axon

9135:CFAP418
gene id: 9135:CFAP418
uniprot id: A0A8C9MKB4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in photoreceptor outer segment disk morphogenesis.
messages: Photoreceptor inner segment

9135:NPFFR2
gene id: 9135:NPFFR2
uniprot id: A0A8C9MM87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

9135:GMNN
gene id: 9135:GMNN
uniprot id: A0A8C9MYL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the geminin family.
messages: Nucleus

9135:THUMPD3
gene id: 9135:THUMPD3
uniprot id: A0A8C9NRH3
names: Similarity
messages: Belongs to the methyltransferase superfamily.

9135:MAN1B1
gene id: 9135:MAN1B1
uniprot id: A0A8C9NCC5
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

9135:IARS2
gene id: 9135:IARS2
uniprot id: A0A8C9MS99
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9135:FGFBP2
gene id: 9135:FGFBP2
uniprot id: A0A8C9KWE1
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

9135:OSGEPL1
gene id: 9135:OSGEPL1
uniprot id: A0A8C9MKI9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Mitochondrion
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.

9135:ATP5PF
gene id: 9135:ATP5PF
uniprot id: A0A8C9NUD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ATPase subunit F6 family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.
messages: Mitochondrion
messages: Mitochondrion inner membrane

9135:RRAGC
gene id: 9135:RRAGC
uniprot id: A0A8C9NQT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

9135:PLA2G4A
gene id: 9135:PLA2G4A
uniprot id: A0A8C9NA03
names: Domain
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.

9135:TAMM41
gene id: 9135:TAMM41
uniprot id: A0A8C9NB78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAM41 family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Mitochondrion inner membrane

9135:TFAP2B
gene id: 9135:TFAP2B
uniprot id: A0A8C9NLR7
names: Similarity
messages: Belongs to the AP-2 family.

9135:SYF2
gene id: 9135:SYF2
uniprot id: A0A8C9MVV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYF2 family.
messages: Involved in pre-mRNA splicing.
messages: May be part of a spliceosome complex.
messages: Nucleus

9135:PSEN1
gene id: 9135:PSEN1
uniprot id: A0A8C9NJW0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Cytoplasmic granule
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: Synapse
messages: The PAL motif is required for normal active site conformation.
messages: axon
messages: neuron projection

9135:CHRNB4
gene id: 9135:CHRNB4
uniprot id: A0A8C9NGC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9135:SFRP2
gene id: 9135:SFRP2
uniprot id: A0A8C9UF79
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:LOC103816423
gene id: 9135:LOC103816423
uniprot id: A0A8C9KTI4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9135:SNX20
gene id: 9135:SNX20
uniprot id: A0A8C9MNM4
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Membrane

9135:EIF4E
gene id: 9135:EIF4E
uniprot id: A0A8C9NM61
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

9135:LOC103820838
gene id: 9135:LOC103820838
uniprot id: A0A8C9MHF5
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

9135:LOC103818463
gene id: 9135:LOC103818463
uniprot id: A0A8C9MHH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: Belongs to the eutherian X-chromosome-specific Armcx family.
messages: Membrane
messages: Vacuole membrane

9135:SLC25A27
gene id: 9135:SLC25A27
uniprot id: A0A8C9UGT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9135:LOC103813311
gene id: 9135:LOC103813311
uniprot id: A0A8C9MSX9
names: Similarity
messages: Belongs to the cytochrome P450 family.

9135:RPA3
gene id: 9135:RPA3
uniprot id: A0A8C9NHU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 3 family.
messages: Nucleus

9135:ALDH1A2
gene id: 9135:ALDH1A2
uniprot id: A0A8C9KT16
uniprot id: A0A8C9L2G5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

9135:GTF2B
gene id: 9135:GTF2B
uniprot id: A0A8C9NKM9
names: Similarity
messages: Belongs to the TFIIB family.

9135:LGR6
gene id: 9135:LGR6
uniprot id: A0A8C9MSS0
uniprot id: A0A8C9MTT7
names: Subcellular Location Annotation
messages: Membrane

9135:POLG
gene id: 9135:POLG
uniprot id: A0A8C9MS45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-A family.
messages: Involved in the replication of mitochondrial DNA. Associates with mitochondrial DNA.
messages: mitochondrion nucleoid

9135:LTA4H
gene id: 9135:LTA4H
uniprot id: A0A8C9MWL7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

9135:CLCN3
gene id: 9135:CLCN3
uniprot id: A0A8C9UDK4
uniprot id: A0A8C9UE33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-3/CLCN3 subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

9135:ELOVL5
gene id: 9135:ELOVL5
uniprot id: A0A8C9N9G7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL5 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: dendrite

9135:OCSTAMP
gene id: 9135:OCSTAMP
uniprot id: A0A8C9UFY9
names: Subcellular Location Annotation
messages: Membrane

9135:PER2
gene id: 9135:PER2
uniprot id: A0A8C9UI29
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9135:ATP23
gene id: 9135:ATP23
uniprot id: A0A8C9KU21
names: Similarity
messages: Belongs to the peptidase M76 family.

9135:AACS
gene id: 9135:AACS
uniprot id: A0A8C9NB92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Converts acetoacetate to acetoacetyl-CoA in the cytosol.
messages: cytosol

9135:PPP2R5A
gene id: 9135:PPP2R5A
uniprot id: A0A8C9MSU8
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

9135:SFXN2
gene id: 9135:SFXN2
uniprot id: A0A8C9NVC2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

9135:LOC103822517
gene id: 9135:LOC103822517
uniprot id: A0A8C9NBU4
names: Caution
names: Function
names: Subunit
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.
messages: Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.

9135:IPPK
gene id: 9135:IPPK
uniprot id: A0A8C9NCJ9
names: Domain
names: Function
names: Similarity
messages: Belongs to the IPK1 type 2 family.
messages: Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
messages: The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.

9135:CILP
gene id: 9135:CILP
uniprot id: A0A8C9N6C6
names: Subcellular Location Annotation
messages: extracellular matrix

9135:KLC1
gene id: 9135:KLC1
uniprot id: A0A8C9MUI4
uniprot id: A0A8C9UA89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

9135:ARPC2
gene id: 9135:ARPC2
uniprot id: A0A8C9NIT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC2 family.
messages: Cell projection
messages: Component of the Arp2/3 complex.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

9135:KHDRBS3
gene id: 9135:KHDRBS3
uniprot id: A0A8C9N040
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KHDRBS family.
messages: Cytoplasm

9135:TRIM32
gene id: 9135:TRIM32
uniprot id: A0A8C9MVP8
names: Similarity
messages: Belongs to the TRIM/RBCC family.

9135:EML4
gene id: 9135:EML4
uniprot id: A0A8C9N2P5
names: Similarity
messages: Belongs to the WD repeat EMAP family.

9135:PSMB2
gene id: 9135:PSMB2
uniprot id: A0A8C9NP54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

9135:HIKESHI
gene id: 9135:HIKESHI
uniprot id: A0A8C9L4N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus.
messages: Belongs to the OPI10 family.
messages: Cytoplasm
messages: Forms an asymmetric homodimer; required for binding and nuclear import of HSP70 proteins. Interacts with ATP-bound HSP70 proteins.
messages: Nucleus
messages: cytosol

9135:TTC36
gene id: 9135:TTC36
uniprot id: A0A8C9NYN7
names: Similarity
messages: Belongs to the TTC36 family.

9135:PTPA
gene id: 9135:PTPA
uniprot id: A0A8C9MP47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

9135:GDPD1
gene id: 9135:GDPD1
uniprot id: A0A8C9N8J2
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

9135:DDX24
gene id: 9135:DDX24
uniprot id: A0A8C9MYJ8
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

9135:ELOVL1
gene id: 9135:ELOVL1
uniprot id: A0A8C9KNL4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL1 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

9135:LOC103821875
gene id: 9135:LOC103821875
uniprot id: A0A8C9KWV6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

9135:TIPARP
gene id: 9135:TIPARP
uniprot id: A0A8C9N2Z6
names: Similarity
messages: Belongs to the ARTD/PARP family.

9135:PSEN2
gene id: 9135:PSEN2
uniprot id: A0A8C9NQX6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: The PAL motif is required for normal active site conformation.

9135:LOC103827199
gene id: 9135:LOC103827199
uniprot id: A0A8C9NQH1
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

9135:ABL2
gene id: 9135:ABL2
uniprot id: A0A8C9N532
uniprot id: A0A8C9N6H0
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

9135:MED24
gene id: 9135:MED24
uniprot id: A0A8C9MZZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 24 family.
messages: Nucleus

9135:LOC103822376
gene id: 9135:LOC103822376
uniprot id: A0A8C9MXK8
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 FAD per subunit.

9135:LOC103824465
gene id: 9135:LOC103824465
uniprot id: A0A8C9MZ02
names: Similarity
messages: Belongs to the globin family.

9135:SLC1A4
gene id: 9135:SLC1A4
uniprot id: A0A8C9KVT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

9135:LDAF1
gene id: 9135:LDAF1
uniprot id: A0A8C9N8X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LDAF1 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Membrane

9135:DDX27
gene id: 9135:DDX27
uniprot id: A0A8C9NHC6
names: Similarity
messages: Belongs to the DEAD box helicase family.

9135:RNH1
gene id: 9135:RNH1
uniprot id: A0A8C9NKM8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Forms high-affinity heterodimers with RNASE1, ANG and RNASE2.
messages: Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play a role in redox homeostasis.

9135:ACVR2B
gene id: 9135:ACVR2B
uniprot id: A0A8C9MVD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

9135:AQP11
gene id: 9135:AQP11
uniprot id: A0A8C9ME59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.
messages: Membrane

9135:CDC42SE2
gene id: 9135:CDC42SE2
uniprot id: A0A8C9NK07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Membrane
messages: cytoskeleton

9135:MMUT
gene id: 9135:MMUT
uniprot id: A0A8C9NJB8
names: Function
names: Similarity
messages: Belongs to the methylmalonyl-CoA mutase family.
messages: Catalyzes the reversible isomerization of methylmalonyl-CoA (MMCoA) (generated from branched-chain amino acid metabolism and degradation of dietary odd chain fatty acids and cholesterol) to succinyl-CoA (3-carboxypropionyl-CoA), a key intermediate of the tricarboxylic acid cycle.

9135:CDC42BPA
gene id: 9135:CDC42BPA
uniprot id: A0A8C9NQV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
messages: lamellipodium

9135:CRYAB
gene id: 9135:CRYAB
uniprot id: A0A8C9MXP5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

9135:ATP6AP1
gene id: 9135:ATP6AP1
uniprot id: A0A8C9U6H9
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

9135:DNAL4
gene id: 9135:DNAL4
uniprot id: A0A8C9MQ19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

9135:TDRD3
gene id: 9135:TDRD3
uniprot id: A0A8C9NR70
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. Plays a role in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, acts as an antiviral factor that participates in the assembly of stress granules together with G3BP1.

9135:TMEM116
gene id: 9135:TMEM116
uniprot id: A0A8C9MY66
names: Subcellular Location Annotation
messages: Membrane

9135:SOD2
gene id: 9135:SOD2
uniprot id: A0A8C9NBQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Homotetramer.
messages: Mitochondrion matrix

9135:OLAH
gene id: 9135:OLAH
uniprot id: A0A8C9NB01
names: Similarity
messages: Belongs to the thioesterase family.

9135:LOC103827017
gene id: 9135:LOC103827017
uniprot id: A0A8C9MNS0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

9135:PRPF18
gene id: 9135:PRPF18
uniprot id: A0A8C9N5K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP18 family.
messages: Nucleus speckle

9135:LOC103824309
gene id: 9135:LOC103824309
uniprot id: A0A8C9KRV2
names: Similarity
messages: Belongs to the ADP-ribosyl cyclase family.

9135:SRP68
gene id: 9135:SRP68
uniprot id: A0A8C9MHG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP68 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER.
messages: Cytoplasm
messages: nucleolus

9135:LOC103813137
gene id: 9135:LOC103813137
uniprot id: A0A8C9U1J6
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

9135:TBL1XR1
gene id: 9135:TBL1XR1
uniprot id: A0A8C9NEA7
names: Similarity
messages: Belongs to the WD repeat EBI family.

9135:CEP162
gene id: 9135:CEP162
uniprot id: A0A8C9MJK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP162 family.
messages: centriole

9135:ALG6
gene id: 9135:ALG6
uniprot id: A0A8C9MVP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9135:PDHX
gene id: 9135:PDHX
uniprot id: A0A8C9MJR2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

9135:LOC103813751
gene id: 9135:LOC103813751
uniprot id: A0A8C9N3V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

9135:CAVIN1
gene id: 9135:CAVIN1
uniprot id: A0A8C9MWW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

9135:LOC103812568
gene id: 9135:LOC103812568
uniprot id: A0A8C9NGJ6
names: Similarity
messages: Belongs to the protein kinase superfamily.

9135:LOC103817867
gene id: 9135:LOC103817867
uniprot id: A0A8C9N3F1
names: Similarity
messages: Belongs to the cytochrome P450 family.

9135:CACFD1
gene id: 9135:CACFD1
uniprot id: A0A8C9MJS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel flower family.
messages: Membrane

9135:NPVF
gene id: 9135:NPVF
uniprot id: A0A8C9NNS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FARP (FMRFamide related peptide) family.
messages: Secreted

9135:PAPOLA
gene id: 9135:PAPOLA
uniprot id: A0A8C9MYH0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Binds 2 magnesium ions. Also active with manganese.
messages: Nucleus
messages: Polymerase that creates the 3'-poly(A) tail of mRNA's.

9135:ADCY8
gene id: 9135:ADCY8
uniprot id: A0A8C9N038
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

9135:STK40
gene id: 9135:STK40
uniprot id: A0A8C9NR94
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be a negative regulator of NF-kappa-B and p53-mediated gene transcription.
messages: Nucleus

9135:LOC103821278
gene id: 9135:LOC103821278
uniprot id: A0A8C9NI94
names: Function
names: Similarity
messages: Belongs to the KCMF1 family.
messages: Has intrinsic E3 ubiquitin ligase activity and promotes ubiquitination.

9135:CRB2
gene id: 9135:CRB2
uniprot id: A0A8C9NU47
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:SCARB2
gene id: 9135:SCARB2
uniprot id: A0A8C9MMY7
uniprot id: A0A8C9U6S3
names: Similarity
messages: Belongs to the CD36 family.

9135:CLIC4
gene id: 9135:CLIC4
uniprot id: A0A8C9MW68
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

9135:CPNE2
gene id: 9135:CPNE2
uniprot id: A0A8C9MTP3
names: Similarity
messages: Belongs to the copine family.

9135:MFSD6
gene id: 9135:MFSD6
uniprot id: A0A8C9MK47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. MFSD6 family.
messages: Membrane

9135:LOC103822653
gene id: 9135:LOC103822653
uniprot id: A0A8C9UH89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9135:SERPINI1
gene id: 9135:SERPINI1
uniprot id: A0A8C9N624
names: Similarity
messages: Belongs to the serpin family.

9135:ZDHHC8
gene id: 9135:ZDHHC8
uniprot id: A0A8C9MP13
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9135:HMOX1
gene id: 9135:HMOX1
uniprot id: A0A8C9MKG6
names: Similarity
messages: Belongs to the heme oxygenase family.

9135:ATPAF1
gene id: 9135:ATPAF1
uniprot id: A0A8C9MIF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP11 family.
messages: Mitochondrion

9135:POLR2D
gene id: 9135:POLR2D
uniprot id: A0A8C9N3S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Nucleus

9135:WNT8A
gene id: 9135:WNT8A
uniprot id: A0A8C9N9W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9135:RNF10
gene id: 9135:RNF10
uniprot id: A0A8C9MKQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNF10 family.
messages: Cytoplasm

9135:NID1
gene id: 9135:NID1
uniprot id: A0A8C9MLU7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

9135:HNF1A
gene id: 9135:HNF1A
uniprot id: A0A8C9MKL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HNF1 homeobox family.
messages: Nucleus

9135:ALDH1L2
gene id: 9135:ALDH1L2
uniprot id: A0A8C9MHS8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
messages: In the N-terminal section; belongs to the GART family.

9135:KATNB1
gene id: 9135:KATNB1
uniprot id: A0A8C9MTC3
uniprot id: A0A8C9MU89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat KATNB1 family.
messages: Cytoplasm
messages: Interacts with KATNA1. This interaction enhances the microtubule binding and severing activity of KATNA1 and also targets this activity to the centrosome.
messages: Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
messages: centrosome
messages: cytoskeleton
messages: spindle
messages: spindle pole

9135:SPOPL
gene id: 9135:SPOPL
uniprot id: A0A8C9N708
names: Similarity
messages: Belongs to the Tdpoz family.

9135:B4GALT6
gene id: 9135:B4GALT6
uniprot id: A0A8C9NDM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

9135:AP1S2
gene id: 9135:AP1S2
uniprot id: A0A8C9NJ34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

9135:PSMD12
gene id: 9135:PSMD12
uniprot id: A0A8C9UGK1
names: Similarity
messages: Belongs to the proteasome subunit p55 family.

9135:CALB2
gene id: 9135:CALB2
uniprot id: A0A8C9MSD8
names: Function
names: Similarity
messages: Belongs to the calbindin family.
messages: Calretinin is a calcium-binding protein which is abundant in auditory neurons.

9135:TRMT1L
gene id: 9135:TRMT1L
uniprot id: A0A8C9NAX1
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: May play a role in motor coordination and exploratory behavior.

9135:PGM2
gene id: 9135:PGM2
uniprot id: A0A8C9MQ16
names: Similarity
messages: Belongs to the phosphohexose mutase family.

9135:MOS
gene id: 9135:MOS
uniprot id: A0A8C9UFW3
names: Similarity
messages: Belongs to the protein kinase superfamily.

9135:CLEC16A
gene id: 9135:CLEC16A
uniprot id: A0A8C9NAE8
names: Similarity
messages: Belongs to the CLEC16A/gop-1 family.

9135:GRIA1
gene id: 9135:GRIA1
uniprot id: A0A8C9NFN7
uniprot id: A0A8C9NGN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

9135:AP3S1
gene id: 9135:AP3S1
uniprot id: A0A8C9MQD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

9135:CABIN1
gene id: 9135:CABIN1
uniprot id: A0A8C9MJD5
names: Subcellular Location Annotation
messages: Nucleus

9135:PTTG1
gene id: 9135:PTTG1
uniprot id: A0A8C9NB88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the securin family.
messages: Cytoplasm
messages: Nucleus

9135:TXNL4B
gene id: 9135:TXNL4B
uniprot id: A0A8C9UI41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

9135:LOC103813335
gene id: 9135:LOC103813335
uniprot id: A0A8C9MUQ2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9135:B3GNT4
gene id: 9135:B3GNT4
uniprot id: A0A8C9N1F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9135:LOC103823301
gene id: 9135:LOC103823301
uniprot id: A0A8C9NUE9
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Contains one covalently linked retinal chromophore.
messages: Membrane

9135:STK39
gene id: 9135:STK39
uniprot id: A0A8C9UHT5
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

9135:NKX6-2
gene id: 9135:NKX6-2
uniprot id: A0A8C9N3W2
names: Subcellular Location Annotation
messages: Nucleus

9135:DYNLL2
gene id: 9135:DYNLL2
uniprot id: A0A8C9N8Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

9135:EIF3L
gene id: 9135:EIF3L
uniprot id: A0A8C9MM55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit L family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

9135:POLR3H
gene id: 9135:POLR3H
uniprot id: A0A8C9UA24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

9135:TMPRSS4
gene id: 9135:TMPRSS4
uniprot id: A0A8C9MQR2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:LOC103813437
gene id: 9135:LOC103813437
uniprot id: A0A8C9N2I2
names: Similarity
messages: Belongs to the CRISP family.

9135:NR2C2
gene id: 9135:NR2C2
uniprot id: A0A8C9NV23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9135:BBS7
gene id: 9135:BBS7
uniprot id: A0A8C9MFN2
names: Function
names: Subunit
messages: Part of BBSome complex.
messages: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.

9135:TPD52L1
gene id: 9135:TPD52L1
uniprot id: A0A8C9NMG9
names: Similarity
messages: Belongs to the TPD52 family.

9135:TOM1
gene id: 9135:TOM1
uniprot id: A0A8C9ML61
names: Similarity
messages: Belongs to the TOM1 family.

9135:TIMM17A
gene id: 9135:TIMM17A
uniprot id: A0A8C9UB39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

9135:TXNIP
gene id: 9135:TXNIP
uniprot id: A0A8C9NC16
names: Similarity
messages: Belongs to the arrestin family.

9135:SUSD6
gene id: 9135:SUSD6
uniprot id: A0A8C9NGL9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:CKAP2
gene id: 9135:CKAP2
uniprot id: A0A8C9NHE4
names: Similarity
messages: Belongs to the CKAP2 family.

9135:ATP6V0D2
gene id: 9135:ATP6V0D2
uniprot id: A0A8C9MGH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

9135:MYOZ2
gene id: 9135:MYOZ2
uniprot id: A0A8C9L3X7
names: Similarity
messages: Belongs to the myozenin family.

9135:LOC103812522
gene id: 9135:LOC103812522
uniprot id: A0A8C9MLA1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

9135:VCL
gene id: 9135:VCL
uniprot id: A0A8C9U240
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction
messages: podosome

9135:MASP1
gene id: 9135:MASP1
uniprot id: A0A8C9NLI4
uniprot id: A0A8C9NQ33
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:LOC103823199
gene id: 9135:LOC103823199
uniprot id: A0A8C9NKN0
names: Subcellular Location Annotation
messages: Membrane

9135:CCT7
gene id: 9135:CCT7
uniprot id: A0A8C9NU93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.

9135:TRAF1
gene id: 9135:TRAF1
uniprot id: A0A8C9L6J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

9135:RBKS
gene id: 9135:RBKS
uniprot id: A0A8C9N5Z5
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

9135:CEMIP2
gene id: 9135:CEMIP2
uniprot id: A0A8C9KUN5
names: Similarity
messages: Belongs to the CEMIP family.

9135:PRKDC
gene id: 9135:PRKDC
uniprot id: A0A8C9NBL9
uniprot id: A0A8C9ND99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family.
messages: nucleolus

9135:ATP2C1
gene id: 9135:ATP2C1
uniprot id: A0A8C9MF55
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9135:PNPLA7
gene id: 9135:PNPLA7
uniprot id: A0A8C9N7C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9135:XRN2
gene id: 9135:XRN2
uniprot id: A0A8C9UGQ2
names: Function
names: Similarity
messages: Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
messages: Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.

9135:NCF2
gene id: 9135:NCF2
uniprot id: A0A8C9NCZ3
names: Similarity
messages: Belongs to the NCF2/NOXA1 family.

9135:YWHAG
gene id: 9135:YWHAG
uniprot id: A0A8C9UAV5
names: Similarity
messages: Belongs to the 14-3-3 family.

9135:RPF2
gene id: 9135:RPF2
uniprot id: A0A8C9L098
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPF2 family.
messages: nucleolus

9135:LOC103813937
gene id: 9135:LOC103813937
uniprot id: A0A8C9UIA9
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

9135:LOC103827344
gene id: 9135:LOC103827344
uniprot id: A0A8C9ND61
uniprot id: A0A8C9NES3
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

9135:PRKCA
gene id: 9135:PRKCA
uniprot id: A0A8C9NHN8
uniprot id: A0A8C9NKZ1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domain.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Mitochondrion membrane
messages: Nucleus

9135:DLX1
gene id: 9135:DLX1
uniprot id: A0A8C9NU63
names: Subcellular Location Annotation
messages: Nucleus

9135:LOC103814507
gene id: 9135:LOC103814507
uniprot id: A0A8C9MGM4
names: Similarity
messages: Belongs to the peptidase C14A family.

9135:ACSL1
gene id: 9135:ACSL1
uniprot id: A0A8C9N826
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

9135:LOC103813245
gene id: 9135:LOC103813245
uniprot id: A0A8C9MLE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

9135:CYFIP1
gene id: 9135:CYFIP1
uniprot id: A0A8C9NVQ7
names: Similarity
messages: Belongs to the CYFIP family.

9135:HCRTR2
gene id: 9135:HCRTR2
uniprot id: A0A8C9N839
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9135:LOC103822177
gene id: 9135:LOC103822177
uniprot id: A0A8C9NB20
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9135:RIOX2
gene id: 9135:RIOX2
uniprot id: A0A8C9ND51
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROX family. MINA53 subfamily.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Nucleus
messages: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.

9135:DNAAF4
gene id: 9135:DNAAF4
uniprot id: A0A8C9KPX5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Dynein axonemal particle
messages: neuron projection

9135:TOM1L2
gene id: 9135:TOM1L2
uniprot id: A0A8C9N1W6
names: Similarity
messages: Belongs to the TOM1 family.

9135:TSPAN14
gene id: 9135:TSPAN14
uniprot id: A0A8C9MHQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9135:HSPA8
gene id: 9135:HSPA8
uniprot id: A0A8C9UDE0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

9135:NSUN6
gene id: 9135:NSUN6
uniprot id: A0A8C9UE55
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

9135:TJP3
gene id: 9135:TJP3
uniprot id: A0A8C9KW48
uniprot id: A0A8C9KW54
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: tight junction

9135:CLDN12
gene id: 9135:CLDN12
uniprot id: A0A8C9NBS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Membrane
messages: tight junction

9135:TOM1L1
gene id: 9135:TOM1L1
uniprot id: A0A8C9NKH3
names: Similarity
messages: Belongs to the TOM1 family.

9135:TSPAN18
gene id: 9135:TSPAN18
uniprot id: A0A8C9MJG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9135:LOC103816747
gene id: 9135:LOC103816747
uniprot id: A0A8C9MWA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Nucleus

9135:LOC103812888
gene id: 9135:LOC103812888
uniprot id: A0A8C9UGU6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

9135:CSNK1G1
gene id: 9135:CSNK1G1
uniprot id: A0A8C9NRY1
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

9135:LOC103817272
gene id: 9135:LOC103817272
uniprot id: A0A8C9UEN1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9135:LHX2
gene id: 9135:LHX2
uniprot id: A0A8C9NSC7
names: Subcellular Location Annotation
messages: Nucleus

9135:EXOSC1
gene id: 9135:EXOSC1
uniprot id: A0A8C9NU26
names: Subcellular Location Annotation
messages: Cytoplasm

9135:PTH
gene id: 9135:PTH
uniprot id: A0A8C9NTU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion.
messages: Secreted

9135:PDIA4
gene id: 9135:PDIA4
uniprot id: A0A8C9NT51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

9135:TMEM183A
gene id: 9135:TMEM183A
uniprot id: A0A8C9MWH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM183 family.
messages: Membrane

9135:PRPH2
gene id: 9135:PRPH2
uniprot id: A0A8C9N1J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRPH2/ROM1 family.
messages: Membrane

9135:GCAT
gene id: 9135:GCAT
uniprot id: A0A8C9MLV5
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

9135:RSPO1
gene id: 9135:RSPO1
uniprot id: A0A8C9NQJ9
names: Similarity
messages: Belongs to the R-spondin family.

9135:SGMS2
gene id: 9135:SGMS2
uniprot id: A0A8C9NI39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

9135:TMEM242
gene id: 9135:TMEM242
uniprot id: A0A8C9NMI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM242 family.
messages: Membrane

9135:INTS7
gene id: 9135:INTS7
uniprot id: A0A8C9MS72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 7 family.
messages: Nucleus

9135:EDNRA
gene id: 9135:EDNRA
uniprot id: A0A8C9NQ93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with HDAC7 and KAT5.
messages: Membrane
messages: Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.

9135:RPS4X
gene id: 9135:RPS4X
uniprot id: A0A8C9NNL0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

9135:LOC103820367
gene id: 9135:LOC103820367
uniprot id: A0A8C9UG82
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9135:YDJC
gene id: 9135:YDJC
uniprot id: A0A8C9MN72
names: Function
names: Similarity
messages: Belongs to the YdjC deacetylase family.
messages: Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides.

9135:ITPRIP
gene id: 9135:ITPRIP
uniprot id: A0A8C9UI78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Membrane

9135:POLR2F
gene id: 9135:POLR2F
uniprot id: A0A8C9MLV7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Component of the RNA polymerase I (Pol I), RNA polymerase II (Pol II) and RNA polymerase III (Pol III) complexes consisting of at least 13, 12 and 17 subunits, respectively.
messages: Nucleus

9135:MOGAT2
gene id: 9135:MOGAT2
uniprot id: A0A8C9NTC0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:LOC103822357
gene id: 9135:LOC103822357
uniprot id: A0A8C9MTG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

9135:ABRACL
gene id: 9135:ABRACL
uniprot id: A0A8C9MID6
uniprot id: A0A8C9U5F2
names: Similarity
messages: Belongs to the costars family.

9135:RAMP2
gene id: 9135:RAMP2
uniprot id: A0A8C9MUD2
names: Similarity
messages: Belongs to the RAMP family.

9135:SOGA1
gene id: 9135:SOGA1
uniprot id: A0A8C9UDC8
names: Similarity
messages: Belongs to the SOGA family.

9135:SFT2D1
gene id: 9135:SFT2D1
uniprot id: A0A8C9NCP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

9135:PPEF1
gene id: 9135:PPEF1
uniprot id: A0A8C9NK52
names: Similarity
messages: Belongs to the PPP phosphatase family.

9135:TARDBP
gene id: 9135:TARDBP
uniprot id: A0A8C9NUL8
names: Subcellular Location Annotation
messages: Nucleus

9135:NEMP2
gene id: 9135:NEMP2
uniprot id: A0A8C9MKC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NEMP family.
messages: Nucleus inner membrane

9135:CA5A
gene id: 9135:CA5A
uniprot id: A0A8C9MWE1
uniprot id: A0A8C9MWH2
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

9135:CSRNP3
gene id: 9135:CSRNP3
uniprot id: A0A8C9NRQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

9135:GSK3B
gene id: 9135:GSK3B
uniprot id: A0A8C9N5Y0
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

9135:LOC103814714
gene id: 9135:LOC103814714
uniprot id: A0A8C9L695
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

9135:RAMAC
gene id: 9135:RAMAC
uniprot id: A0A8C9MQ62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAM family.
messages: Nucleus

9135:IGF1
gene id: 9135:IGF1
uniprot id: A0A8C9N654
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

9135:ARFGEF1
gene id: 9135:ARFGEF1
uniprot id: A0A8C9L2A3
names: Subcellular Location Annotation
messages: Golgi apparatus
messages: perinuclear region

9135:LOC103822068
gene id: 9135:LOC103822068
uniprot id: A0A8C9MWV0
names: Similarity
messages: Belongs to the perilipin family.

9135:AQP1
gene id: 9135:AQP1
uniprot id: A0A8C9MT26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

9135:TNK2
gene id: 9135:TNK2
uniprot id: A0A8C9NIY1
uniprot id: A0A8C9NPV8
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus

9135:NR2C1
gene id: 9135:NR2C1
uniprot id: A0A8C9UC13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9135:GNPDA1
gene id: 9135:GNPDA1
uniprot id: A0A8C9KXH8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

9135:CASR
gene id: 9135:CASR
uniprot id: A0A8C9UEX5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9135:SPON1
gene id: 9135:SPON1
uniprot id: A0A8C9MYX5
names: Subcellular Location Annotation
messages: extracellular matrix

9135:XPOT
gene id: 9135:XPOT
uniprot id: A0A8C9MGY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus
messages: tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.

9135:PIGK
gene id: 9135:PIGK
uniprot id: A0A8C9NNV1
names: Similarity
names: Subunit
messages: Belongs to the peptidase C13 family.
messages: Forms a complex with PIGT, PIGS, PIGU and GAA1.

9135:EIF4EBP1
gene id: 9135:EIF4EBP1
uniprot id: A0A8C9NXF2
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

9135:GRHL2
gene id: 9135:GRHL2
uniprot id: A0A8C9MM99
names: Subcellular Location Annotation
messages: Nucleus

9135:RTN4IP1
gene id: 9135:RTN4IP1
uniprot id: A0A8C9KQ88
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

9135:SNRPD1
gene id: 9135:SNRPD1
uniprot id: A0A8C9MFJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.

9135:CLTRN
gene id: 9135:CLTRN
uniprot id: A0A8C9NL95
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9135:PLOD1
gene id: 9135:PLOD1
uniprot id: A0A8C9MHX3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

9135:FAM118A
gene id: 9135:FAM118A
uniprot id: A0A8C9MI46
names: Similarity
messages: Belongs to the FAM118 family.

9135:MAFF
gene id: 9135:MAFF
uniprot id: A0A8C9MML2
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

9135:GPNMB
gene id: 9135:GPNMB
uniprot id: A0A8C9NM05
names: Similarity
messages: Belongs to the PMEL/NMB family.

9135:LOC103823012
gene id: 9135:LOC103823012
uniprot id: A0A8C9NKT0
names: Subcellular Location Annotation
messages: Membrane

9135:LOC103813054
gene id: 9135:LOC103813054
uniprot id: A0A8C9MVC9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
messages: Binds 1 FAD per subunit.
messages: May have a photoreceptor function.

9135:IFT57
gene id: 9135:IFT57
uniprot id: A0A8C9NWM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFT57 family.
messages: cilium basal body

9135:PDE1A
gene id: 9135:PDE1A
uniprot id: A0A8C9KXS9
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9135:DHCR7
gene id: 9135:DHCR7
uniprot id: A0A8C9UCM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

9135:HPDL
gene id: 9135:HPDL
uniprot id: A0A8C9L2V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4HPPD family.
messages: Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

9135:PLCG2
gene id: 9135:PLCG2
uniprot id: A0A8C9MUW4
names: Function
messages: Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.

9135:NLGN4X
gene id: 9135:NLGN4X
uniprot id: A0A8C9MPZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

9135:RAB3B
gene id: 9135:RAB3B
uniprot id: A0A8C9MSI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

9135:TGFB2
gene id: 9135:TGFB2
uniprot id: A0A8C9U8U7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.
messages: extracellular matrix

9135:STS
gene id: 9135:STS
uniprot id: A0A8C9U812
names: Similarity
messages: Belongs to the sulfatase family.

9135:SLC20A2
gene id: 9135:SLC20A2
uniprot id: A0A8C9NGM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter.

9135:LOC103816564
gene id: 9135:LOC103816564
uniprot id: A0A8C9KX07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9135:PTPRZ1
gene id: 9135:PTPRZ1
uniprot id: A0A8C9KVJ0
uniprot id: A0A8C9KVN1
uniprot id: A0A8C9L0V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily.
messages: Membrane

9135:ZBTB8OS
gene id: 9135:ZBTB8OS
uniprot id: A0A8C9MPH8
names: Similarity
names: Subunit
messages: Belongs to the archease family.
messages: Component of the tRNA-splicing ligase complex.

9135:KIF3B
gene id: 9135:KIF3B
uniprot id: A0A8C9NL84
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9135:CHST1
gene id: 9135:CHST1
uniprot id: A0A8C9U1R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

9135:LOC103813352
gene id: 9135:LOC103813352
uniprot id: A0A8C9UBC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9135:TES
gene id: 9135:TES
uniprot id: A0A8C9UDH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prickle / espinas / testin family.
messages: focal adhesion

9135:NINJ2
gene id: 9135:NINJ2
uniprot id: A0A8C9MM81
uniprot id: A0A8C9MMA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ninjurin family.
messages: Membrane

9135:CDKAL1
gene id: 9135:CDKAL1
uniprot id: A0A8C9L1K2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
messages: Endoplasmic reticulum membrane

9135:SLC39A14
gene id: 9135:SLC39A14
uniprot id: A0A8C9MSB5
names: Subcellular Location Annotation
messages: Membrane

9135:C21H1orf174
gene id: 9135:C21H1orf174
uniprot id: A0A8C9L3Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0688 family.
messages: Nucleus

9135:MTIF3
gene id: 9135:MTIF3
uniprot id: A0A8C9MUG4
names: Similarity
messages: Belongs to the IF-3 family.

9135:INS
gene id: 9135:INS
uniprot id: A0A8C9MM83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the insulin family.
messages: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
messages: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
messages: Secreted

9135:ARF6
gene id: 9135:ARF6
uniprot id: A0A8C9ME01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Cell membrane
messages: Cleavage furrow
messages: Endosome membrane
messages: Midbody ring
messages: Recycling endosome membrane
messages: filopodium membrane
messages: ruffle

9135:HAT1
gene id: 9135:HAT1
uniprot id: A0A8C9NSV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAT1 family.
messages: Catalytic subunit of the type B histone acetyltransferase (HAT) complex, composed of RBBP7 and HAT1. Interacts with histones H4 and H2A.
messages: Histone acetyltransferase that plays a role in different biological processes including cell cycle progression, glucose metabolism, histone production or DNA damage repair. Coordinates histone production and acetylation via H4 promoter binding. Acetylates histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, histone H2A at 'Lys-5' (H2AK5ac).

9135:RNMT
gene id: 9135:RNMT
uniprot id: A0A8C9MY23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
messages: In the N-terminal section; belongs to the dsDNA virus mRNA guanylyltransferase family.
messages: Nucleus

9135:LOC103820072
gene id: 9135:LOC103820072
uniprot id: A0A8C9UAT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft.
messages: Nucleus

9135:MAGOH
gene id: 9135:MAGOH
uniprot id: A0A8C9MSD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mago nashi family.
messages: Nucleus

9135:BCO2
gene id: 9135:BCO2
uniprot id: A0A8C9MYS4
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

9135:SPECC1L
gene id: 9135:SPECC1L
uniprot id: A0A8C9MJT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytospin-A family.
messages: Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration.
messages: May interact with both microtubules and actin cytoskeleton.
messages: cytoskeleton
messages: gap junction
messages: spindle

9135:AOPEP
gene id: 9135:AOPEP
uniprot id: A0A8C9MMD2
names: Similarity
messages: Belongs to the peptidase M1 family.

9135:KIF20B
gene id: 9135:KIF20B
uniprot id: A0A8C9NW39
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9135:NCDN
gene id: 9135:NCDN
uniprot id: A0A8C9UHP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurochondrin family.
messages: Postsynapse

9135:PDGFB
gene id: 9135:PDGFB
uniprot id: A0A8C9MPD2
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

9135:INSIG1
gene id: 9135:INSIG1
uniprot id: A0A8C9MXF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Mediates feedback control of cholesterol synthesis.
messages: Membrane

9135:SH3PXD2B
gene id: 9135:SH3PXD2B
uniprot id: A0A8C9L297
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3PXD2 family.
messages: Cytoplasm

9135:LOC103820078
gene id: 9135:LOC103820078
uniprot id: A0A8C9MU15
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADPH--cytochrome P450 reductase family.
messages: Binds 1 FAD per monomer.
messages: Binds 1 FMN per monomer.
messages: Endoplasmic reticulum membrane
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5.

9135:ETS2
gene id: 9135:ETS2
uniprot id: A0A8C9N948
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus
messages: Transcription factor.

9135:CFAP97
gene id: 9135:CFAP97
uniprot id: A0A8C9N3T9
names: Similarity
messages: Belongs to the CFAP97 family.

9135:RPAP1
gene id: 9135:RPAP1
uniprot id: A0A8C9MEF5
names: Similarity
messages: Belongs to the RPAP1 family.

9135:SATB1
gene id: 9135:SATB1
uniprot id: A0A8C9NMG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

9135:TMEM41B
gene id: 9135:TMEM41B
uniprot id: A0A8C9MPX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM41 family.
messages: Membrane

9135:SHROOM3
gene id: 9135:SHROOM3
uniprot id: A0A8C9MMT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

9135:ARSG
gene id: 9135:ARSG
uniprot id: A0A8C9NJE7
names: Similarity
messages: Belongs to the sulfatase family.

9135:RTCA
gene id: 9135:RTCA
uniprot id: A0A8C9NGP6
names: Function
names: Similarity
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.

9135:SNX30
gene id: 9135:SNX30
uniprot id: A0A8C9MHC7
names: Similarity
messages: Belongs to the sorting nexin family.

9135:KCNG1
gene id: 9135:KCNG1
uniprot id: A0A8C9NSW3
names: Subcellular Location Annotation
messages: Membrane

9135:WEE1
gene id: 9135:WEE1
uniprot id: A0A8C9MR27
names: Cofactor
names: Similarity
messages: Belongs to the protein kinase superfamily.
messages: Binds 2 magnesium ions per subunit.

9135:RPL7
gene id: 9135:RPL7
uniprot id: A0A8C9KUY6
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

9135:ATG16L1
gene id: 9135:ATG16L1
uniprot id: A0A8C9MIA1
uniprot id: A0A8C9MIC0
names: Similarity
messages: Belongs to the WD repeat ATG16 family.

9135:LOC103817748
gene id: 9135:LOC103817748
uniprot id: A0A8C9NES8
names: Similarity
messages: Belongs to the globin family.

9135:LOC103820858
gene id: 9135:LOC103820858
uniprot id: A0A8C9MIW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylin family.
messages: Secreted

9135:LOC103826067
gene id: 9135:LOC103826067
uniprot id: A0A8C9NNR8
names: Similarity
messages: Belongs to the AF4 family.

9135:LTN1
gene id: 9135:LTN1
uniprot id: A0A8C9NQK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LTN1 family.
messages: Component of the ribosome quality control complex (RQC).
messages: E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.
messages: cytosol

9135:SSX2IP
gene id: 9135:SSX2IP
uniprot id: A0A8C9NNC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIP family.
messages: adherens junction
messages: centriolar satellite

9135:ETV1
gene id: 9135:ETV1
uniprot id: A0A8C9NF69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9135:GRK4
gene id: 9135:GRK4
uniprot id: A0A8C9NRA1
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

9135:UTRN
gene id: 9135:UTRN
uniprot id: A0A8C9MGY4
names: Function
names: Subcellular Location Annotation
messages: May play a role in anchoring the cytoskeleton to the plasma membrane.
messages: cytoskeleton

9135:GSKIP
gene id: 9135:GSKIP
uniprot id: A0A8C9MXV9
names: Similarity
messages: Belongs to the GSKIP family.

9135:SLC4A7
gene id: 9135:SLC4A7
uniprot id: A0A8C9KPB0
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane

9135:CCNB2
gene id: 9135:CCNB2
uniprot id: A0A8C9NWF8
names: Similarity
messages: Belongs to the cyclin family.

9135:SRP54
gene id: 9135:SRP54
uniprot id: A0A8C9NAE3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Nucleus speckle
messages: The M domain binds the 7SL RNA in presence of SRP19 and binds the signal sequence of presecretory proteins.
messages: The NG domain, also named G domain, is a special guanosine triphosphatase (GTPase) domain, which binds GTP and forms a guanosine 5'-triphosphate (GTP)-dependent complex with a homologous NG domain in the SRP receptor subunit SRPRA. The two NG domains undergo cooperative rearrangements upon their assembly, which culminate in the reciprocal activation of the GTPase activity of one another. SRP receptor compaction upon binding with cargo-loaded SRP and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER.

9135:MKNK1
gene id: 9135:MKNK1
uniprot id: A0A8C9MIE7
names: Similarity
messages: Belongs to the protein kinase superfamily.

9135:TATDN1
gene id: 9135:TATDN1
uniprot id: A0A8C9MXG7
uniprot id: A0A8C9MY28
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

9135:SULF1
gene id: 9135:SULF1
uniprot id: A0A8C9KX63
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

9135:RPS2
gene id: 9135:RPS2
uniprot id: A0A8C9U9W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Nucleus

9135:EEF2KMT
gene id: 9135:EEF2KMT
uniprot id: A0A8C9NDS0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EEF2KMT family.

9135:SDHAF2
gene id: 9135:SDHAF2
uniprot id: A0A8C9N4L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SDHAF2 family.
messages: Interacts with SDHA within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer.

9135:C26H6orf89
gene id: 9135:C26H6orf89
uniprot id: A0A8C9UFW4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

9135:RAB38
gene id: 9135:RAB38
uniprot id: A0A8C9MHZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

9135:SGO2
gene id: 9135:SGO2
uniprot id: A0A8C9MGW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

9135:TSPAN5
gene id: 9135:TSPAN5
uniprot id: A0A8C9NJE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9135:LPAR1
gene id: 9135:LPAR1
uniprot id: A0A8C9UED4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cell surface
messages: Endosome
messages: Membrane

9135:IMPACT
gene id: 9135:IMPACT
uniprot id: A0A8C9NDK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IMPACT family.
messages: Cytoplasm

9135:CNDP2
gene id: 9135:CNDP2
uniprot id: A0A8C9MXL4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

9135:MAPK14
gene id: 9135:MAPK14
uniprot id: A0A8C9NLR1
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

9135:OXSM
gene id: 9135:OXSM
uniprot id: A0A8C9NQ05
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

9135:LOC103826301
gene id: 9135:LOC103826301
uniprot id: A0A8C9L091
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9135:AHSA1
gene id: 9135:AHSA1
uniprot id: A0A8C9N2U0
names: Similarity
messages: Belongs to the AHA1 family.

9135:PLA2G4B
gene id: 9135:PLA2G4B
uniprot id: A0A8C9KXE4
uniprot id: A0A8C9MEB5
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

9135:ERG
gene id: 9135:ERG
uniprot id: A0A8C9N685
uniprot id: A0A8C9N959
uniprot id: A0A8C9NBG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9135:LOC103815348
gene id: 9135:LOC103815348
uniprot id: A0A8C9UGV7
names: Similarity
messages: Belongs to the cytochrome P450 family.

9135:HUS1
gene id: 9135:HUS1
uniprot id: A0A8C9NRY3
names: Similarity
messages: Belongs to the HUS1 family.

9135:XIAP
gene id: 9135:XIAP
uniprot id: A0A8C9UIP6
names: Similarity
messages: Belongs to the IAP family.

9135:EEIG1
gene id: 9135:EEIG1
uniprot id: A0A8C9UBF4
names: Similarity
messages: Belongs to the EEIG family.

9135:ROCK1
gene id: 9135:ROCK1
uniprot id: A0A8C9N7N7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by RHOA binding. Inhibited by Y-27632.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cytoplasm
messages: Homodimer.
messages: Membrane
messages: Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.

9135:HTR1F
gene id: 9135:HTR1F
uniprot id: A0A8C9ND58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
messages: Membrane

9135:DRAXIN
gene id: 9135:DRAXIN
uniprot id: A0A8C9MI35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the draxin family.
messages: Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord.
messages: Secreted

9135:CHST15
gene id: 9135:CHST15
uniprot id: A0A8C9NEZ5
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9135:TIMP3
gene id: 9135:TIMP3
uniprot id: A0A8C9MKS0
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

9135:C2H7orf25
gene id: 9135:C2H7orf25
uniprot id: A0A8C9NSU3
names: Similarity
messages: Belongs to the UPF0415 family.

9135:GFUS
gene id: 9135:GFUS
uniprot id: A0A8C9L241
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

9135:CEP55
gene id: 9135:CEP55
uniprot id: A0A8C9NWP7
names: Subcellular Location Annotation
messages: Cytoplasm

9135:ST3GAL3
gene id: 9135:ST3GAL3
uniprot id: A0A8C9KT55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9135:EPS8L2
gene id: 9135:EPS8L2
uniprot id: A0A8C9NBF4
names: Similarity
messages: Belongs to the EPS8 family.

9135:GPR34
gene id: 9135:GPR34
uniprot id: A0A8C9NDQ4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9135:ESYT3
gene id: 9135:ESYT3
uniprot id: A0A8C9N8L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the extended synaptotagmin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

9135:SLC15A1
gene id: 9135:SLC15A1
uniprot id: A0A8C9NT44
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Interacts (via extracellular domain region) with trypsin.
messages: Membrane

9135:LOC103823865
gene id: 9135:LOC103823865
uniprot id: A0A8C9N120
names: Similarity
messages: Belongs to the intermediate filament family.

9135:GRIA4
gene id: 9135:GRIA4
uniprot id: A0A8C9MMB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

9135:FZD9
gene id: 9135:FZD9
uniprot id: A0A8C9MKL4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9135:LOC103821589
gene id: 9135:LOC103821589
uniprot id: A0A8C9MUJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

9135:CD8B
gene id: 9135:CD8B
uniprot id: A0A8C9UH80
names: Subcellular Location Annotation
messages: Membrane

9135:HOXA1
gene id: 9135:HOXA1
uniprot id: A0A8C9NMS2
names: Subcellular Location Annotation
messages: Nucleus

9135:LOC103818472
gene id: 9135:LOC103818472
uniprot id: A0A8C9MI18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

9135:RBL1
gene id: 9135:RBL1
uniprot id: A0A8C9NDD5
uniprot id: A0A8C9NFG8
uniprot id: A0A8C9NFH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

9135:BCORL1
gene id: 9135:BCORL1
uniprot id: A0A8C9NS79
names: Similarity
messages: Belongs to the BCOR family.

9135:KIF2C
gene id: 9135:KIF2C
uniprot id: A0A8C9L2U0
uniprot id: A0A8C9L555
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9135:ACADM
gene id: 9135:ACADM
uniprot id: A0A8C9UCC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Mitochondrion matrix

9135:PEMT
gene id: 9135:PEMT
uniprot id: A0A8C9N2Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
messages: Catalyzes the three sequential steps of the methylation pathway for the biosynthesis of phosphatidylcholine, a critical and essential component for membrane structure. Uses S-adenosylmethionine (S-adenosyl-L-methionine, SAM or AdoMet) as the methyl group donor for the methylation of phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE) to phosphatidylmonomethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine, PMME), PMME to phosphatidyldimethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine, PDME), and PDME to phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine, PC), producing S-adenosyl-L-homocysteine in each step.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

9135:CD2
gene id: 9135:CD2
uniprot id: A0A8C9NF71
names: Subcellular Location Annotation
messages: Membrane

9135:DDIT4
gene id: 9135:DDIT4
uniprot id: A0A8C9NS15
names: Similarity
messages: Belongs to the DDIT4 family.

9135:CHUK
gene id: 9135:CHUK
uniprot id: A0A8C9MMH9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9135:STEAP2
gene id: 9135:STEAP2
uniprot id: A0A8C9NFK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

9135:LYRM7
gene id: 9135:LYRM7
uniprot id: A0A8C9NJZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane.
messages: Belongs to the complex I LYR family.
messages: Interacts with UQCRFS1.
messages: Mitochondrion matrix

9135:LOC103813354
gene id: 9135:LOC103813354
uniprot id: A0A8C9MU87
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9135:RAB11FIP4
gene id: 9135:RAB11FIP4
uniprot id: A0A8C9NNK8
names: Subcellular Location Annotation
messages: Cleavage furrow
messages: Endosome membrane
messages: Membrane
messages: Midbody
messages: Recycling endosome membrane

9135:ELOVL2
gene id: 9135:ELOVL2
uniprot id: A0A8C9L3L1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL2 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

9135:ORC5
gene id: 9135:ORC5
uniprot id: A0A8C9MY86
names: Subcellular Location Annotation
messages: Nucleus

9135:SLC6A9
gene id: 9135:SLC6A9
uniprot id: A0A8C9KQ85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A9 subfamily.
messages: Cell membrane
messages: Membrane

9135:FAM110C
gene id: 9135:FAM110C
uniprot id: A0A8C9NBX6
names: Similarity
messages: Belongs to the FAM110 family.

9135:PDP2
gene id: 9135:PDP2
uniprot id: A0A8C9NCK3
names: Similarity
messages: Belongs to the PP2C family.

9135:TALDO1
gene id: 9135:TALDO1
uniprot id: A0A8C9N6M0
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.

9135:OIP5
gene id: 9135:OIP5
uniprot id: A0A8C9MFZ3
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
messages: centromere

9135:ZW10
gene id: 9135:ZW10
uniprot id: A0A8C9MQV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZW10 family.
messages: kinetochore

9135:GADD45G
gene id: 9135:GADD45G
uniprot id: A0A8C9NKC1
names: Similarity
messages: Belongs to the GADD45 family.

9135:NDNF
gene id: 9135:NDNF
uniprot id: A0A8C9L4N6
names: Subcellular Location Annotation
messages: Secreted

9135:SSTR3
gene id: 9135:SSTR3
uniprot id: A0A8C9ML93
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9135:MRE11
gene id: 9135:MRE11
uniprot id: A0A8C9MJP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRE11/RAD32 family.
messages: Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
messages: Nucleus

9135:LOC108961658
gene id: 9135:LOC108961658
uniprot id: A0A8C9NW86
names: Function
messages: The products of the Gag polyproteins of infectious retroviruses perform highly complex orchestrated tasks during the assembly, budding, maturation, and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA. Endogenous Gag proteins may have kept, lost or modified their original function during evolution.

9135:PDCD4
gene id: 9135:PDCD4
uniprot id: A0A8C9NRJ4
names: Similarity
messages: Belongs to the PDCD4 family.

9135:LOC103826618
gene id: 9135:LOC103826618
uniprot id: A0A8C9NJJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX16 family.
messages: Membrane
messages: Mitochondrion inner membrane

9135:SLC5A3
gene id: 9135:SLC5A3
uniprot id: A0A8C9MZ96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

9135:FICD
gene id: 9135:FICD
uniprot id: A0A8C9MWP0
names: Similarity
messages: Belongs to the fic family.

9135:CSGALNACT1
gene id: 9135:CSGALNACT1
uniprot id: A0A8C9UFN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

9135:RPL36A
gene id: 9135:RPL36A
uniprot id: A0A8C9NUU9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

9135:PSMB1
gene id: 9135:PSMB1
uniprot id: A0A8C9MIK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

9135:LOC103826977
gene id: 9135:LOC103826977
uniprot id: A0A8C9ME61
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

9135:PLCD1
gene id: 9135:PLCD1
uniprot id: A0A8C9MVP7
names: Cofactor
messages: Binds 3 Ca(2+) ions per subunit. Two of the Ca(2+) ions are bound to the C2 domain.

9135:DDX47
gene id: 9135:DDX47
uniprot id: A0A8C9MSW8
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.

9135:LOC103816462
gene id: 9135:LOC103816462
uniprot id: A0A8C9MJL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

9135:TMPRSS2
gene id: 9135:TMPRSS2
uniprot id: A0A8C9N6S4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:FAM13A
gene id: 9135:FAM13A
uniprot id: A0A8C9NLL6
names: Similarity
messages: Belongs to the FAM13 family.

9135:LOC103814390
gene id: 9135:LOC103814390
uniprot id: A0A8C9NPX3
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the peptidase S9B family. DPPIV subfamily.
messages: Cell junction
messages: Cell membrane
messages: Membrane raft
messages: invadopodium membrane
messages: lamellipodium membrane

9135:DPY30
gene id: 9135:DPY30
uniprot id: A0A8C9NB04
names: Similarity
messages: Belongs to the dpy-30 family.

9135:NAT10
gene id: 9135:NAT10
uniprot id: A0A8C9N2K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.
messages: Interacts with THUMPD1.
messages: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA-binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
messages: nucleolus

9135:GAP43
gene id: 9135:GAP43
uniprot id: A0A8C9UDG7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the neuromodulin family.
messages: Binds calmodulin with a greater affinity in the absence of Ca(2+) than in its presence.
messages: Cell membrane
messages: Membrane
messages: Palmitoylated. Palmitoylation is essential for plasma membrane association.
messages: Synapse
messages: This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.
messages: filopodium membrane
messages: growth cone membrane

9135:DPH5
gene id: 9135:DPH5
uniprot id: A0A8C9NC96
names: Function
names: Similarity
messages: Belongs to the diphthine synthase family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

9135:CETP
gene id: 9135:CETP
uniprot id: A0A8C9MUI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Secreted

9135:LOC103815302
gene id: 9135:LOC103815302
uniprot id: A0A8C9NB57
uniprot id: A0A8C9UF01
names: Subcellular Location Annotation
messages: Membrane

9135:SGMS1
gene id: 9135:SGMS1
uniprot id: A0A8C9MKC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

9135:CACNG1
gene id: 9135:CACNG1
uniprot id: A0A8C9NM18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either CACNB1 or CACNB2.
messages: Membrane
messages: Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
messages: sarcolemma

9135:SLC25A4
gene id: 9135:SLC25A4
uniprot id: A0A8C9N5H5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

9135:NRG3
gene id: 9135:NRG3
uniprot id: A0A8C9U3G8
names: Caution
names: Similarity
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:DHRS7
gene id: 9135:DHRS7
uniprot id: A0A8C9MPG8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9135:ETFRF1
gene id: 9135:ETFRF1
uniprot id: A0A8C9UDH5
names: Similarity
messages: Belongs to the complex I LYR family.

9135:INTS2
gene id: 9135:INTS2
uniprot id: A0A8C9NAJ5
names: Similarity
messages: Belongs to the Integrator subunit 2 family.

9135:TUBGCP2
gene id: 9135:TUBGCP2
uniprot id: A0A8C9MLS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

9135:NDC1
gene id: 9135:NDC1
uniprot id: A0A8C9MSU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDC1 family.
messages: Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane.
messages: Membrane
messages: Nucleus membrane
messages: nuclear pore complex

9135:FAM91A1
gene id: 9135:FAM91A1
uniprot id: A0A8C9MX95
names: Similarity
messages: Belongs to the FAM91 family.

9135:IRF7
gene id: 9135:IRF7
uniprot id: A0A8C9NPP2
names: Subcellular Location Annotation
messages: Nucleus

9135:DHX9
gene id: 9135:DHX9
uniprot id: A0A8C9NAG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DEAH subfamily.
messages: Nucleus

9135:ENTPD1
gene id: 9135:ENTPD1
uniprot id: A0A8C9UI31
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

9135:IRF4
gene id: 9135:IRF4
uniprot id: A0A8C9L4G8
names: Subcellular Location Annotation
messages: Nucleus

9135:RPSA
gene id: 9135:RPSA
uniprot id: A0A8C9KYX1
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acylated. Acylation may be a prerequisite for conversion of the monomeric 37 kDa laminin receptor precursor (37LRP) to the mature dimeric 67 kDa laminin receptor (67LR), and may provide a mechanism for membrane association.
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Cell membrane
messages: Cleaved by stromelysin-3 (ST3) at the cell surface. Cleavage by stromelysin-3 may be a mechanism to alter cell-extracellular matrix interactions.
messages: Cytoplasm
messages: Monomer (37LRP) and homodimer (67LR). Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Interacts with RPS21. Interacts with several laminins including at least LAMB1. Interacts with MDK.
messages: Nucleus
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis.
messages: This protein appears to have acquired a second function as a laminin receptor specifically in the vertebrate lineage.

9135:STK3
gene id: 9135:STK3
uniprot id: A0A8C9ML23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Nucleus

9135:AGA
gene id: 9135:AGA
uniprot id: A0A8C9N8M5
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

9135:LOC103818081
gene id: 9135:LOC103818081
uniprot id: A0A8C9MMN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Midbody
messages: cilium membrane
messages: spindle

9135:DPF3
gene id: 9135:DPF3
uniprot id: A0A8C9NHK1
names: Similarity
messages: Belongs to the requiem/DPF family.

9135:NCOA3
gene id: 9135:NCOA3
uniprot id: A0A8C9NSY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.
messages: Nucleus

9135:TMEM35B
gene id: 9135:TMEM35B
uniprot id: A0A8C9NSY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

9135:AMN
gene id: 9135:AMN
uniprot id: A0A8C9MVI6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9135:ZNF830
gene id: 9135:ZNF830
uniprot id: A0A8C9MSI7
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus speckle

9135:POP5
gene id: 9135:POP5
uniprot id: A0A8C9U5K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
messages: nucleolus

9135:BTD
gene id: 9135:BTD
uniprot id: A0A8C9UGY3
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

9135:ZC3H12D
gene id: 9135:ZC3H12D
uniprot id: A0A8C9N1J6
names: Similarity
messages: Belongs to the ZC3H12 family.

9135:CPSF2
gene id: 9135:CPSF2
uniprot id: A0A8C9MY35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

9135:UBL3
gene id: 9135:UBL3
uniprot id: A0A8C9MW50
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9135:DIPK2B
gene id: 9135:DIPK2B
uniprot id: A0A8C9NC15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Secreted

9135:PDE6D
gene id: 9135:PDE6D
uniprot id: A0A8C9NKJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PDE6D/unc-119 family.
messages: Cytoplasmic vesicle membrane
messages: Interacts with the prenylated catalytic subunits of PDE6, an oligomer composed of two catalytic chains and two inhibitory chains; has no effect on enzyme activity but promotes the release of the prenylated enzyme from cell membrane.
messages: Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate.
messages: cilium basal body
messages: cytosol

9135:LOC103817749
gene id: 9135:LOC103817749
uniprot id: A0A8C9NAF1
names: Similarity
messages: Belongs to the globin family.

9135:LOC103816689
gene id: 9135:LOC103816689
uniprot id: A0A8C9U971
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9135:LOC103827099
gene id: 9135:LOC103827099
uniprot id: A0A8C9N4R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

9135:VAC14
gene id: 9135:VAC14
uniprot id: A0A8C9MRR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VAC14 family.
messages: Endosome membrane
messages: Microsome membrane

9135:DESI1
gene id: 9135:DESI1
uniprot id: A0A8C9MRQ3
names: Similarity
messages: Belongs to the DeSI family.

9135:LOC103827373
gene id: 9135:LOC103827373
uniprot id: A0A8C9NG39
names: Subcellular Location Annotation
messages: Secreted

9135:SLC5A7
gene id: 9135:SLC5A7
uniprot id: A0A8C9MIE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

9135:HOOK1
gene id: 9135:HOOK1
uniprot id: A0A8C9MV91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hook family.
messages: cytoskeleton

9135:NDUFB6
gene id: 9135:NDUFB6
uniprot id: A0A8C9UG34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB6 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9135:GTPBP4
gene id: 9135:GTPBP4
uniprot id: A0A8C9N210
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

9135:MTOR
gene id: 9135:MTOR
uniprot id: A0A8C9MIP3
uniprot id: A0A8C9U5J3
names: Similarity
messages: Belongs to the PI3/PI4-kinase family.

9135:FSHB
gene id: 9135:FSHB
uniprot id: A0A8C9UCD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

9135:DUSP6
gene id: 9135:DUSP6
uniprot id: A0A8C9MXU3
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

9135:GRAMD1B
gene id: 9135:GRAMD1B
uniprot id: A0A8C9UEF1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9135:BLVRA
gene id: 9135:BLVRA
uniprot id: A0A8C9NQS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family. Biliverdin reductase subfamily.
messages: Monomer.
messages: Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor.
messages: cytosol

9135:ST6GAL2
gene id: 9135:ST6GAL2
uniprot id: A0A8C9MIB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9135:IGF2R
gene id: 9135:IGF2R
uniprot id: A0A8C9NAW4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:NCBP2
gene id: 9135:NCBP2
uniprot id: A0A8C9NQM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRM NCBP2 family.
messages: Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U snRNA and intronless mRNAs export from the nucleus. The CBC complex is essential for a pioneer round of mRNA translation, before steady state translation when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. The pioneer round of mRNA translation mediated by the CBC complex plays a central role in nonsense-mediated mRNA decay (NMD), NMD only taking place in mRNAs bound to the CBC complex, but not on eIF4E-bound mRNAs. The CBC complex enhances NMD in mRNAs containing at least one exon-junction complex (EJC), promoting the interaction between upf1 and upf2. The CBC complex is also involved in 'failsafe' NMD, which is independent of the EJC complex, while it does not participate in Staufen-mediated mRNA decay (SMD). During cell proliferation, the CBC complex is also involved in microRNAs (miRNAs) biogenesis via its interaction with srrt/ars2, thereby being required for miRNA-mediated RNA interference. The CBC complex also acts as a negative regulator of parn, thereby acting as an inhibitor of mRNA deadenylation. In the CBC complex, ncbp2/cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp1/cbp80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure. The conventional cap-binding complex with NCBP2 binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus.
messages: Component of the nuclear cap-binding complex (CBC), a heterodimer composed of ncbp1/cbp80 and ncbp2/cbp20 that interacts with m7GpppG-capped RNA.
messages: Nucleus

9135:NDUFB3
gene id: 9135:NDUFB3
uniprot id: A0A8C9U258
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB3 subunit family.
messages: Mitochondrion inner membrane

9135:NDUFV2
gene id: 9135:NDUFV2
uniprot id: A0A8C9UDB7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.

9135:GLRA2
gene id: 9135:GLRA2
uniprot id: A0A8C9NK11
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

9135:CHD1L
gene id: 9135:CHD1L
uniprot id: A0A8C9N6I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

9135:TAF9B
gene id: 9135:TAF9B
uniprot id: A0A8C9ME89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus

9135:ANAPC5
gene id: 9135:ANAPC5
uniprot id: A0A8C9N435
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC5 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: spindle

9135:KCNJ8
gene id: 9135:KCNJ8
uniprot id: A0A8C9UD34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

9135:INHBA
gene id: 9135:INHBA
uniprot id: A0A8C9NS70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

9135:HVCN1
gene id: 9135:HVCN1
uniprot id: A0A8C9N0F0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hydrogen channel family.
messages: Homodimer.
messages: Membrane

9135:ELOVL7
gene id: 9135:ELOVL7
uniprot id: A0A8C9N3U2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL7 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0-, or C26:0-CoAs. May participate to the production of saturated and polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9135:LOC103817999
gene id: 9135:LOC103817999
uniprot id: A0A8C9MJB3
names: Similarity
messages: Belongs to the GST superfamily. Theta family.

9135:LOC108961603
gene id: 9135:LOC108961603
uniprot id: A0A8C9N4J2
names: Subcellular Location Annotation
messages: Nucleus

9135:NPY5R
gene id: 9135:NPY5R
uniprot id: A0A8C9NAC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders.

9135:LOC103825988
gene id: 9135:LOC103825988
uniprot id: A0A8C9UFM2
names: Subcellular Location Annotation
messages: Membrane

9135:RPA1
gene id: 9135:RPA1
uniprot id: A0A8C9MWF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
messages: Belongs to the replication factor A protein 1 family.
messages: Component of the heterotrimeric canonical replication protein A complex (RPA).
messages: PML body

9135:EEF1B2
gene id: 9135:EEF1B2
uniprot id: A0A8C9MFK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: EF-1 is composed of 4 subunits: alpha, beta, delta, and gamma.
messages: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.

9135:LOC103823091
gene id: 9135:LOC103823091
uniprot id: A0A8C9N860
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9135:AMOT
gene id: 9135:AMOT
uniprot id: A0A8C9NUA9
names: Similarity
messages: Belongs to the angiomotin family.

9135:CEP70
gene id: 9135:CEP70
uniprot id: A0A8C9N744
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Directly interacts with tubulin-gamma; this interaction determines centrosomal localization.
messages: Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle.
messages: centrosome

9135:THRB
gene id: 9135:THRB
uniprot id: A0A8C9NNQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
messages: Nucleus

9135:NMUR1
gene id: 9135:NMUR1
uniprot id: A0A8C9UGZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

9135:NTRK2
gene id: 9135:NTRK2
uniprot id: A0A8C9MN49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

9135:ITIH5
gene id: 9135:ITIH5
uniprot id: A0A8C9N5G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

9135:CELF6
gene id: 9135:CELF6
uniprot id: A0A8C9NU92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Nucleus

9135:AMPD3
gene id: 9135:AMPD3
uniprot id: A0A8C9MZZ6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

9135:PITX3
gene id: 9135:PITX3
uniprot id: A0A8C9L4R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

9135:GSTK1
gene id: 9135:GSTK1
uniprot id: A0A8C9NJH2
names: Similarity
messages: Belongs to the GST superfamily. Kappa family.

9135:ACOX3
gene id: 9135:ACOX3
uniprot id: A0A8C9NPQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

9135:QRFP
gene id: 9135:QRFP
uniprot id: A0A8C9MLW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFamide neuropeptide family.
messages: Secreted

9135:UTP6
gene id: 9135:UTP6
uniprot id: A0A8C9NMP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP6 family.
messages: nucleolus

9135:PHTF1
gene id: 9135:PHTF1
uniprot id: A0A8C9NLP4
names: Subcellular Location Annotation
messages: Membrane

9135:PFKFB2
gene id: 9135:PFKFB2
uniprot id: A0A8C9NEG0
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

9135:SEMA3A
gene id: 9135:SEMA3A
uniprot id: A0A8C9N318
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:LOC103822463
gene id: 9135:LOC103822463
uniprot id: A0A8C9NFJ7
names: Similarity
messages: Belongs to the peptidase M14 family.

9135:GMFB
gene id: 9135:GMFB
uniprot id: A0A8C9MFG6
names: Similarity
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.

9135:CHST9
gene id: 9135:CHST9
uniprot id: A0A8C9NE08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

9135:LOC103813884
gene id: 9135:LOC103813884
uniprot id: A0A8C9KU12
names: Similarity
messages: Belongs to the TMEM14 family.

9135:VIPR1
gene id: 9135:VIPR1
uniprot id: A0A8C9UB05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

9135:LOC103824142
gene id: 9135:LOC103824142
uniprot id: A0A8C9NM73
uniprot id: A0A8C9NPS6
uniprot id: A0A8C9NTG2
names: Similarity
messages: Belongs to the CAND family.

9135:HRH2
gene id: 9135:HRH2
uniprot id: A0A8C9NHS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9135:LOC103826433
gene id: 9135:LOC103826433
uniprot id: A0A8C9UC27
names: Similarity
messages: Belongs to the cytochrome P450 family.

9135:DIS3L2
gene id: 9135:DIS3L2
uniprot id: A0A8C9NM74
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation.
messages: Belongs to the RNR ribonuclease family. DIS3L2 subfamily.
messages: Cytoplasm
messages: P-body
messages: Specifically recognizes and binds polyuridylated RNAs via 3 RNA-binding regions (named U-zone 1, U-zone 2 and U-zone 3) that form an open funnel on one face of the catalytic domain, allowing RNA to navigate a path to the active site.

9135:GPR107
gene id: 9135:GPR107
uniprot id: A0A8C9MPN5
names: Subcellular Location Annotation
messages: Membrane

9135:WASHC5
gene id: 9135:WASHC5
uniprot id: A0A8C9MY92
names: Similarity
messages: Belongs to the strumpellin family.

9135:TOP2A
gene id: 9135:TOP2A
uniprot id: A0A8C9MYB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Homodimer.
messages: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand.
messages: nucleolus
messages: nucleoplasm

9135:SENP7
gene id: 9135:SENP7
uniprot id: A0A8C9NQ30
uniprot id: A0A8C9NSF9
uniprot id: A0A8C9NW97
names: Similarity
messages: Belongs to the peptidase C48 family.

9135:AGTR2
gene id: 9135:AGTR2
uniprot id: A0A8C9UJ18
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with MTUS1.
messages: Membrane

9135:USP9X
gene id: 9135:USP9X
uniprot id: A0A8C9UEY3
names: Similarity
messages: Belongs to the peptidase C19 family.

9135:CFLAR
gene id: 9135:CFLAR
uniprot id: A0A8C9MGP2
names: Similarity
messages: Belongs to the peptidase C14A family.

9135:CWF19L2
gene id: 9135:CWF19L2
uniprot id: A0A8C9MM30
names: Similarity
messages: Belongs to the CWF19 family.

9135:LOC103814506
gene id: 9135:LOC103814506
uniprot id: A0A8C9MGI2
names: Similarity
messages: Belongs to the peptidase C14A family.

9135:MTF2
gene id: 9135:MTF2
uniprot id: A0A8C9UG29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus

9135:NR4A3
gene id: 9135:NR4A3
uniprot id: A0A8C9UB97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9135:CCKAR
gene id: 9135:CCKAR
uniprot id: A0A8C9MNZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

9135:HOXA3
gene id: 9135:HOXA3
uniprot id: A0A8C9UGW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

9135:MNAT1
gene id: 9135:MNAT1
uniprot id: A0A8C9MTE8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with CDK7 and cyclin H.
messages: Nucleus
messages: Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.

9135:ZER1
gene id: 9135:ZER1
uniprot id: A0A8C9MPZ0
names: Similarity
messages: Belongs to the zyg-11 family.

9135:NRDE2
gene id: 9135:NRDE2
uniprot id: A0A8C9N113
names: Similarity
messages: Belongs to the NRDE2 family.

9135:MTTP
gene id: 9135:MTTP
uniprot id: A0A8C9NKV2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:NSFL1C
gene id: 9135:NSFL1C
uniprot id: A0A8C9NMN0
names: Subcellular Location Annotation
messages: Golgi stack

9135:CIRBP
gene id: 9135:CIRBP
uniprot id: A0A8C9MT01
uniprot id: A0A8C9MV41
names: Subcellular Location Annotation
messages: Cytoplasm
messages: nucleoplasm

9135:LOC103813291
gene id: 9135:LOC103813291
uniprot id: A0A8C9MGC7
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

9135:LOC103826245
gene id: 9135:LOC103826245
uniprot id: A0A8C9NFW6
names: Subcellular Location Annotation
messages: Membrane

9135:FAT1
gene id: 9135:FAT1
uniprot id: A0A8C9N4Q3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:TRPM7
gene id: 9135:TRPM7
uniprot id: A0A8C9MQG7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: In the C-terminal section; belongs to the protein kinase superfamily. Alpha-type protein kinase family. ALPK subfamily.
messages: Membrane

9135:TMEM182
gene id: 9135:TMEM182
uniprot id: A0A8C9U3E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM182 family.
messages: Cell membrane
messages: Membrane

9135:VPS37B
gene id: 9135:VPS37B
uniprot id: A0A8C9N4I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

9135:SNX2
gene id: 9135:SNX2
uniprot id: A0A8C9MQH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: lamellipodium

9135:TLCD2
gene id: 9135:TLCD2
uniprot id: A0A8C9MWN4
names: Subcellular Location Annotation
messages: Membrane

9135:CTSD
gene id: 9135:CTSD
uniprot id: A0A8C9MME9
names: Similarity
messages: Belongs to the peptidase A1 family.

9135:GPR180
gene id: 9135:GPR180
uniprot id: A0A8C9NS13
names: Subcellular Location Annotation
messages: Membrane

9135:FASN
gene id: 9135:FASN
uniprot id: A0A8C9NAN2
names: Function
messages: Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ([ACP]) domain.

9135:POLR3A
gene id: 9135:POLR3A
uniprot id: A0A8C9MH49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

9135:GPR87
gene id: 9135:GPR87
uniprot id: A0A8C9N0V1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9135:TBX3
gene id: 9135:TBX3
uniprot id: A0A8C9MMV9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9135:ARG2
gene id: 9135:ARG2
uniprot id: A0A8C9NH99
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

9135:EIPR1
gene id: 9135:EIPR1
uniprot id: A0A8C9NC35
names: Similarity
messages: Belongs to the WD repeat EIPR1 family.

9135:GPM6B
gene id: 9135:GPM6B
uniprot id: A0A8C9NEQ8
uniprot id: A0A8C9NJV3
uniprot id: A0A8C9UFT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

9135:PDP1
gene id: 9135:PDP1
uniprot id: A0A8C9MHS9
names: Similarity
messages: Belongs to the PP2C family.

9135:LYPLAL1
gene id: 9135:LYPLAL1
uniprot id: A0A8C9MS54
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

9135:TLR4
gene id: 9135:TLR4
uniprot id: A0A8C9UAC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

9135:MAML3
gene id: 9135:MAML3
uniprot id: A0A8C9NGL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

9135:CBLB
gene id: 9135:CBLB
uniprot id: A0A8C9NQ77
uniprot id: A0A8C9NSK2
names: Domain
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

9135:DHRS11
gene id: 9135:DHRS11
uniprot id: A0A8C9N917
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9135:ASIC4
gene id: 9135:ASIC4
uniprot id: A0A8C9NJE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
messages: Membrane

9135:NLGN3
gene id: 9135:NLGN3
uniprot id: A0A8C9NVI1
uniprot id: A0A8C9NXQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

9135:MC4R
gene id: 9135:MC4R
uniprot id: A0A8C9MK11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).

9135:SNRPA1
gene id: 9135:SNRPA1
uniprot id: A0A8C9N5N7
names: Similarity
messages: Belongs to the U2 small nuclear ribonucleoprotein A family.

9135:MC3R
gene id: 9135:MC3R
uniprot id: A0A8C9NP74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane

9135:LOC103812980
gene id: 9135:LOC103812980
uniprot id: A0A8C9KU93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

9135:GPR89B
gene id: 9135:GPR89B
uniprot id: A0A8C9NDL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Golgi pH regulator (TC 1.A.38) family.
messages: Membrane

9135:ELOC
gene id: 9135:ELOC
uniprot id: A0A8C9KUI0
names: Similarity
messages: Belongs to the SKP1 family.

9135:PRKCQ
gene id: 9135:PRKCQ
uniprot id: A0A8C9NHI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

9135:SLC50A1
gene id: 9135:SLC50A1
uniprot id: A0A8C9NG04
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWEET sugar transporter family.
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates sugar transport across membranes.
messages: Membrane

9135:ZGPAT
gene id: 9135:ZGPAT
uniprot id: A0A8C9NM12
names: Subcellular Location Annotation
messages: Nucleus

9135:RAB3GAP1
gene id: 9135:RAB3GAP1
uniprot id: A0A8C9N6J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab3-GAP catalytic subunit family.
messages: Cytoplasm
messages: Endoplasmic reticulum

9135:PTPRF
gene id: 9135:PTPRF
uniprot id: A0A8C9L1G2
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.

9135:UPK1B
gene id: 9135:UPK1B
uniprot id: A0A8C9N551
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9135:STX11
gene id: 9135:STX11
uniprot id: A0A8C9U2N1
names: Similarity
messages: Belongs to the syntaxin family.

9135:CPO
gene id: 9135:CPO
uniprot id: A0A8C9MFT0
names: Similarity
messages: Belongs to the peptidase M14 family.

9135:SERPINF1
gene id: 9135:SERPINF1
uniprot id: A0A8C9MWY0
names: Similarity
messages: Belongs to the serpin family.

9135:TM9SF3
gene id: 9135:TM9SF3
uniprot id: A0A8C9MDP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

9135:SULT1C4
gene id: 9135:SULT1C4
uniprot id: A0A8C9MIF5
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9135:LOC103813169
gene id: 9135:LOC103813169
uniprot id: A0A8C9KXD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

9135:THPO
gene id: 9135:THPO
uniprot id: A0A8C9NJ48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPO/TPO family.
messages: Secreted

9135:ATE1
gene id: 9135:ATE1
uniprot id: A0A8C9NJZ4
names: Function
names: Similarity
messages: Belongs to the R-transferase family.
messages: Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway.

9135:SLC39A9
gene id: 9135:SLC39A9
uniprot id: A0A8C9NE94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Cell membrane
messages: Membrane
messages: Mitochondrion
messages: Nucleus
messages: Transports zinc ions across cell and organelle membranes into the cytoplasm and regulates intracellular zinc homeostasis. Participates in the zinc ions efflux out of the secretory compartments. Also functions as membrane androgen receptor that mediates, through a G protein, the non-classical androgen signaling pathway, characterized by the activation of MAPK3/MAPK1 (Erk1/2) and transcription factors CREB1 or ATF1. Moreover, has dual functions as membrane-bound androgen receptor and as an androgen-dependent zinc transporter both of which are mediated through an inhibitory G protein (Gi) that mediates both MAP kinase and zinc signaling leading to the androgen-dependent apoptotic process.
messages: perinuclear region
messages: trans-Golgi network membrane

9135:POLR3B
gene id: 9135:POLR3B
uniprot id: A0A8C9MIR7
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

9135:LOC103818471
gene id: 9135:LOC103818471
uniprot id: A0A8C9MI31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

9135:SULF2
gene id: 9135:SULF2
uniprot id: A0A8C9NSW6
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

9135:LOC103819060
gene id: 9135:LOC103819060
uniprot id: A0A8C9UDG2
names: Similarity
messages: Belongs to the glutamine synthetase family.

9135:PRPF38B
gene id: 9135:PRPF38B
uniprot id: A0A8C9NCG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP38 family.
messages: May be required for pre-mRNA splicing.
messages: Nucleus

9135:TMEM50B
gene id: 9135:TMEM50B
uniprot id: A0A8C9MNV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

9135:EGFL7
gene id: 9135:EGFL7
uniprot id: A0A8C9MIT3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:ANXA13
gene id: 9135:ANXA13
uniprot id: A0A8C9MVY8
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

9135:ACMSD
gene id: 9135:ACMSD
uniprot id: A0A8C9N9F4
uniprot id: A0A8C9NAZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. ACMSD family.
messages: Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway.
messages: Monomer.

9135:ABL1
gene id: 9135:ABL1
uniprot id: A0A8C9MML1
uniprot id: A0A8C9U6R8
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

9135:PLPP5
gene id: 9135:PLPP5
uniprot id: A0A8C9UIT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

9135:SPOUT1
gene id: 9135:SPOUT1
uniprot id: A0A8C9MPF2
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily.

9135:LOC103812646
gene id: 9135:LOC103812646
uniprot id: A0A8C9MH53
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

9135:VCAN
gene id: 9135:VCAN
uniprot id: A0A8C9MZN5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9135:C1GALT1
gene id: 9135:C1GALT1
uniprot id: A0A8C9NFX7
uniprot id: A0A8C9NHH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.
messages: Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins.
messages: Membrane

9135:FTH1
gene id: 9135:FTH1
uniprot id: A0A8C9N3P7
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

9135:TRMT13
gene id: 9135:TRMT13
uniprot id: A0A8C9NEJ1
names: Function
names: Similarity
messages: Belongs to the methyltransferase TRM13 family.
messages: tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).

9135:CALHM2
gene id: 9135:CALHM2
uniprot id: A0A8C9NTA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

9135:REEP3
gene id: 9135:REEP3
uniprot id: A0A8C9MKE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

9135:CCNI
gene id: 9135:CCNI
uniprot id: A0A8C9MM32
names: Similarity
messages: Belongs to the cyclin family.

9135:LARS2
gene id: 9135:LARS2
uniprot id: A0A8C9MFG7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9135:CHPF2
gene id: 9135:CHPF2
uniprot id: A0A8C9UDF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

9135:LOC103812987
gene id: 9135:LOC103812987
uniprot id: A0A8C9MF92
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9135:LOC103820550
gene id: 9135:LOC103820550
uniprot id: A0A8C9NC45
names: Similarity
messages: Belongs to the protein kinase superfamily.

9135:OCIAD1
gene id: 9135:OCIAD1
uniprot id: A0A8C9MXB7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OCIAD1 family.
messages: Endosome
messages: Interacts with STAT3.
messages: Maintains stem cell potency. Increases STAT3 phosphorylation and controls ERK phosphorylation. May act as a scaffold, increasing STAT3 recruitment onto endosomes.
messages: The OCIA domain is necessary and sufficient for endosomal localization.

9135:ADCY9
gene id: 9135:ADCY9
uniprot id: A0A8C9NGF7
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

9135:EPC2
gene id: 9135:EPC2
uniprot id: A0A8C9MZK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enhancer of polycomb family.
messages: Nucleus

9135:EMX2
gene id: 9135:EMX2
uniprot id: A0A8C9UGW9
names: Subcellular Location Annotation
messages: Nucleus

9135:RNASEH1
gene id: 9135:RNASEH1
uniprot id: A0A8C9NEW2
names: Function
names: Similarity
messages: Belongs to the RNase H family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

9135:CCDC85A
gene id: 9135:CCDC85A
uniprot id: A0A8C9UGR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC85 family.
messages: adherens junction

9135:MAPK1IP1L
gene id: 9135:MAPK1IP1L
uniprot id: A0A8C9MFS6
names: Similarity
messages: Belongs to the MISS family.

9135:LOC103824742
gene id: 9135:LOC103824742
uniprot id: A0A8C9NQS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenium-binding protein family.
messages: Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria. Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport.
messages: Membrane
messages: Nucleus
messages: cytosol

9135:TNFRSF1A
gene id: 9135:TNFRSF1A
uniprot id: A0A8C9UDZ9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:SRP19
gene id: 9135:SRP19
uniprot id: A0A8C9NV79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP19 family.
messages: Cytoplasm

9135:STAT3
gene id: 9135:STAT3
uniprot id: A0A8C9MV58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

9135:ADGRF5
gene id: 9135:ADGRF5
uniprot id: A0A8C9NLI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

9135:EVA1A
gene id: 9135:EVA1A
uniprot id: A0A8C9NLB1
names: Similarity
messages: Belongs to the EVA1 family.

9135:RCAN2
gene id: 9135:RCAN2
uniprot id: A0A8C9NLB8
names: Function
names: Similarity
messages: Belongs to the RCAN family.
messages: Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.

9135:TNFSF8
gene id: 9135:TNFSF8
uniprot id: A0A8C9MUQ9
names: Similarity
messages: Belongs to the tumor necrosis factor family.

9135:LSM8
gene id: 9135:LSM8
uniprot id: A0A8C9KTH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.

9135:RFTN2
gene id: 9135:RFTN2
uniprot id: A0A8C9U4F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the raftlin family.
messages: Cell membrane
messages: Membrane

9135:GPR18
gene id: 9135:GPR18
uniprot id: A0A8C9NR26
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9135:TMTC4
gene id: 9135:TMTC4
uniprot id: A0A8C9NTK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

9135:DHRS7B
gene id: 9135:DHRS7B
uniprot id: A0A8C9N2N9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9135:CGA
gene id: 9135:CGA
uniprot id: A0A8C9MJ41
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit alpha family.
messages: Heterodimer of an alpha and a beta chain.
messages: Secreted

9135:CAP2
gene id: 9135:CAP2
uniprot id: A0A8C9KQS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAP family.
messages: Cell membrane

9135:LOC103816959
gene id: 9135:LOC103816959
uniprot id: A0A8C9KTQ0
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:NKD1
gene id: 9135:NKD1
uniprot id: A0A8C9MN18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKD family.
messages: Cell autonomous antagonist of the canonical Wnt signaling pathway.
messages: Cell membrane
messages: Cytoplasm

9135:LOC103820010
gene id: 9135:LOC103820010
uniprot id: A0A8C9MIP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
messages: Membrane

9135:LOC103817482
gene id: 9135:LOC103817482
uniprot id: A0A8C9NEQ0
names: Subcellular Location Annotation
messages: Cytoplasm

9135:DRAM2
gene id: 9135:DRAM2
uniprot id: A0A8C9UB06
names: Subcellular Location Annotation
messages: Membrane

9135:GALR2
gene id: 9135:GALR2
uniprot id: A0A8C9MHB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

9135:NSMCE4A
gene id: 9135:NSMCE4A
uniprot id: A0A8C9NL44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE4 family.
messages: Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
messages: Component of the SMC5-SMC6 complex.
messages: Nucleus
messages: telomere

9135:TRAPPC2L
gene id: 9135:TRAPPC2L
uniprot id: A0A8C9MVF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

9135:ACTL6A
gene id: 9135:ACTL6A
uniprot id: A0A8C9NFE7
names: Similarity
messages: Belongs to the actin family.

9135:IMPA1
gene id: 9135:IMPA1
uniprot id: A0A8C9MG64
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

9135:LOC103822543
gene id: 9135:LOC103822543
uniprot id: A0A8C9NDC2
uniprot id: A0A8C9UFG8
names: Similarity
messages: Belongs to the MS4A family.

9135:SGK3
gene id: 9135:SGK3
uniprot id: A0A8C9NLI9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

9135:FOXJ2
gene id: 9135:FOXJ2
uniprot id: A0A8C9NMS5
names: Subcellular Location Annotation
messages: Nucleus

9135:LOC103815752
gene id: 9135:LOC103815752
uniprot id: A0A8C9NCT9
uniprot id: A0A8C9UE84
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

9135:SLC22A18
gene id: 9135:SLC22A18
uniprot id: A0A8C9MP29
names: Subcellular Location Annotation
messages: Membrane

9135:UPP1
gene id: 9135:UPP1
uniprot id: A0A8C9MRE5
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

9135:SEC22C
gene id: 9135:SEC22C
uniprot id: A0A8C9MTB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in vesicle transport between the ER and the Golgi complex.
messages: Membrane

9135:RPL31
gene id: 9135:RPL31
uniprot id: A0A8C9KTP4
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Component of the large ribosomal subunit.

9135:LOC103820785
gene id: 9135:LOC103820785
uniprot id: A0A8C9NV92
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

9135:CNDP1
gene id: 9135:CNDP1
uniprot id: A0A8C9MXT4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

9135:FGFR1OP2
gene id: 9135:FGFR1OP2
uniprot id: A0A8C9UCW4
names: Similarity
messages: Belongs to the SIKE family.

9135:CASP2
gene id: 9135:CASP2
uniprot id: A0A8C9NQY3
names: Similarity
messages: Belongs to the peptidase C14A family.

9135:LOC103813345
gene id: 9135:LOC103813345
uniprot id: A0A8C9UBC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9135:CEP57
gene id: 9135:CEP57
uniprot id: A0A8C9MKJ1
names: Similarity
messages: Belongs to the translokin family.

9135:OCRL
gene id: 9135:OCRL
uniprot id: A0A8C9NMB1
uniprot id: A0A8C9NU76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: phagosome membrane

9135:IWS1
gene id: 9135:IWS1
uniprot id: A0A8C9MI39
uniprot id: A0A8C9U3I9
names: Subcellular Location Annotation
messages: Nucleus

9135:MIGA1
gene id: 9135:MIGA1
uniprot id: A0A8C9NLX8
names: Similarity
messages: Belongs to the mitoguardin family.

9135:MRPS36
gene id: 9135:MRPS36
uniprot id: A0A8C9MVD9
names: Subcellular Location Annotation
messages: Mitochondrion

9135:LOC103817416
gene id: 9135:LOC103817416
uniprot id: A0A8C9N240
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9135:GPR158
gene id: 9135:GPR158
uniprot id: A0A8C9N5I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9135:MAP3K8
gene id: 9135:MAP3K8
uniprot id: A0A8C9N3D0
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

9135:LOC103814676
gene id: 9135:LOC103814676
uniprot id: A0A8C9NL13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9135:UPF2
gene id: 9135:UPF2
uniprot id: A0A8C9UDM2
names: Subcellular Location Annotation
messages: Cytoplasm

9135:PTAFR
gene id: 9135:PTAFR
uniprot id: A0A8C9NP69
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with ARRB1.
messages: Membrane

9135:HJV
gene id: 9135:HJV
uniprot id: A0A8C9NDA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

9135:S1PR3
gene id: 9135:S1PR3
uniprot id: A0A8C9NJQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9135:LOC103820479
gene id: 9135:LOC103820479
uniprot id: A0A8C9MUE2
names: Similarity
messages: Belongs to the aldo/keto reductase family.

9135:ULK3
gene id: 9135:ULK3
uniprot id: A0A8C9UFQ4
names: Similarity
messages: Belongs to the protein kinase superfamily.

9135:LOC103818208
gene id: 9135:LOC103818208
uniprot id: A0A8C9KW39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P2X receptor family.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

9135:GDNF
gene id: 9135:GDNF
uniprot id: A0A8C9MYE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

9135:AP1M1
gene id: 9135:AP1M1
uniprot id: A0A8C9NQW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Golgi apparatus
messages: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
messages: clathrin-coated vesicle membrane

9135:RPN2
gene id: 9135:RPN2
uniprot id: A0A8C9NDK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SWP1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

9135:MDFIC
gene id: 9135:MDFIC
uniprot id: A0A8C9N4U9
names: Similarity
messages: Belongs to the MDFI family.

9135:DDC
gene id: 9135:DDC
uniprot id: A0A8C9MRP7
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

9135:CD40LG
gene id: 9135:CD40LG
uniprot id: A0A8C9MKF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a ligand for integrins, specifically ITGA5:ITGB1 and ITGAV:ITGB3; both integrins and the CD40 receptor are required for activation of CD40-CD40LG signaling, which have cell-type dependent effects, such as B-cell activation, NF-kappa-B signaling and anti-apoptotic signaling.
messages: Belongs to the tumor necrosis factor family.
messages: Cell surface

9135:ASPH
gene id: 9135:ASPH
uniprot id: A0A8C9NLW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.
messages: Membrane

9135:LIMK2
gene id: 9135:LIMK2
uniprot id: A0A8C9MK39
uniprot id: A0A8C9MKG9
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

9135:HEBP1
gene id: 9135:HEBP1
uniprot id: A0A8C9MV32
names: Similarity
messages: Belongs to the HEBP family.

9135:EPB42
gene id: 9135:EPB42
uniprot id: A0A8C9UFX8
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.

9135:NCOA2
gene id: 9135:NCOA2
uniprot id: A0A8C9KTI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.
messages: Nucleus

9135:DR1
gene id: 9135:DR1
uniprot id: A0A8C9NJ77
names: Similarity
messages: Belongs to the NC2 beta/DR1 family.

9135:SGCB
gene id: 9135:SGCB
uniprot id: A0A8C9MYP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
messages: Cross-link to form 2 major subcomplexes: one consisting of SGCB, SGCD and SGCG and the other consisting of SGCB and SGCD. The association between SGCB and SGCG is particularly strong while SGCA is loosely associated with the other sarcoglycans.
messages: cytoskeleton
messages: sarcolemma

9135:TIMM9
gene id: 9135:TIMM9
uniprot id: A0A8C9MRB2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

9135:CPAMD8
gene id: 9135:CPAMD8
uniprot id: A0A8C9MKZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

9135:STX3
gene id: 9135:STX3
uniprot id: A0A8C9N584
uniprot id: A0A8C9N5T5
uniprot id: A0A8C9N6U7
names: Similarity
messages: Belongs to the syntaxin family.

9135:BUD31
gene id: 9135:BUD31
uniprot id: A0A8C9UCN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BUD31 (G10) family.
messages: Nucleus

9135:PCID2
gene id: 9135:PCID2
uniprot id: A0A8C9U855
names: Similarity
messages: Belongs to the CSN12 family.

9135:ATOH7
gene id: 9135:ATOH7
uniprot id: A0A8C9UEY2
names: Subcellular Location Annotation
messages: Nucleus
messages: Perikaryon
messages: axon

9135:PROKR1
gene id: 9135:PROKR1
uniprot id: A0A8C9MY30
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9135:FAM221A
gene id: 9135:FAM221A
uniprot id: A0A8C9NQA8
names: Similarity
messages: Belongs to the FAM221 family.

9135:SLC39A10
gene id: 9135:SLC39A10
uniprot id: A0A8C9MI11
names: Subcellular Location Annotation
messages: Membrane

9135:API5
gene id: 9135:API5
uniprot id: A0A8C9MJL3
names: Similarity
messages: Belongs to the API5 family.

9135:P2RX5
gene id: 9135:P2RX5
uniprot id: A0A8C9N5K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

9135:ABCD2
gene id: 9135:ABCD2
uniprot id: A0A8C9MPY8
names: Subcellular Location Annotation
messages: Membrane

9135:TSPAN8
gene id: 9135:TSPAN8
uniprot id: A0A8C9N1U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9135:MAK16
gene id: 9135:MAK16
uniprot id: A0A8C9NB35
names: Similarity
messages: Belongs to the MAK16 family.

9135:PDPR
gene id: 9135:PDPR
uniprot id: A0A8C9MRL0
names: Similarity
messages: Belongs to the GcvT family.

9135:LOC103814915
gene id: 9135:LOC103814915
uniprot id: A0A8C9NN96
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

9135:ACAA1
gene id: 9135:ACAA1
uniprot id: A0A8C9MVS6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

9135:TMOD2
gene id: 9135:TMOD2
uniprot id: A0A8C9MNS3
names: Subcellular Location Annotation
messages: cytoskeleton

9135:TBXA2R
gene id: 9135:TBXA2R
uniprot id: A0A8C9L2G8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9135:FGD4
gene id: 9135:FGD4
uniprot id: A0A8C9N3U8
names: Subcellular Location Annotation
messages: cytoskeleton

9135:LOC103815789
gene id: 9135:LOC103815789
uniprot id: A0A8C9NE69
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

9135:POLR1A
gene id: 9135:POLR1A
uniprot id: A0A8C9NLP5
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

9135:IST1
gene id: 9135:IST1
uniprot id: A0A8C9UCR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IST1 family.
messages: Cytoplasmic vesicle
messages: Nucleus envelope

9135:IREB2
gene id: 9135:IREB2
uniprot id: A0A8C9UF70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Cytoplasm

9135:MEOX1
gene id: 9135:MEOX1
uniprot id: A0A8C9MVW1
names: Subcellular Location Annotation
messages: Nucleus

9135:AGPAT5
gene id: 9135:AGPAT5
uniprot id: A0A8C9UEV1
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

9135:SDR16C5
gene id: 9135:SDR16C5
uniprot id: A0A8C9UFW7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9135:NDUFB4
gene id: 9135:NDUFB4
uniprot id: A0A8C9N615
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB4 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9135:TM2D3
gene id: 9135:TM2D3
uniprot id: A0A8C9UIF9
names: Subcellular Location Annotation
messages: Membrane

9135:CCDC85C
gene id: 9135:CCDC85C
uniprot id: A0A8C9MWF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC85 family.
messages: adherens junction

9135:AIDA
gene id: 9135:AIDA
uniprot id: A0A8C9MYN6
names: Similarity
messages: Belongs to the AIDA family.

9135:TRDMT1
gene id: 9135:TRDMT1
uniprot id: A0A8C9N9E9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

9135:SDHA
gene id: 9135:SDHA
uniprot id: A0A8C9MT28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

9135:CSNK2A1
gene id: 9135:CSNK2A1
uniprot id: A0A8C9NMI1
names: Similarity
messages: Belongs to the protein kinase superfamily.

9135:TEKT1
gene id: 9135:TEKT1
uniprot id: A0A8C9NIV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

9135:SNX33
gene id: 9135:SNX33
uniprot id: A0A8C9NIA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

9135:POLB
gene id: 9135:POLB
uniprot id: A0A8C9NTC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Cytoplasm
messages: DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
messages: Nucleus

9135:LOC103823905
gene id: 9135:LOC103823905
uniprot id: A0A8C9N1H3
names: Similarity
messages: Belongs to the intermediate filament family.

9135:LOC103818219
gene id: 9135:LOC103818219
uniprot id: A0A8C9KTU6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

9135:GCNT4
gene id: 9135:GCNT4
uniprot id: A0A8C9MNY6
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

9135:CIAPIN1
gene id: 9135:CIAPIN1
uniprot id: A0A8C9MTY1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anamorsin family.
messages: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit. Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion intermembrane space
messages: Monomer. Interacts with NDOR1. Interacts with CHCHD4.
messages: Nucleus
messages: The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.
messages: The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.
messages: The twin Cx2C motifs are involved in the recognition by the mitochondrial CHCHD4/MIA40-GFER/ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.

9135:F7
gene id: 9135:F7
uniprot id: A0A8C9MM07
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9135:PPA1
gene id: 9135:PPA1
uniprot id: A0A8C9UHK9
names: Similarity
messages: Belongs to the PPase family.

9135:LOC103824329
gene id: 9135:LOC103824329
uniprot id: A0A8C9NYV9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selectin/LECAM family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9135:PTPN12
gene id: 9135:PTPN12
uniprot id: A0A8C9MZE5
uniprot id: A0A8C9MZK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 4 subfamily.
messages: Cytoplasm
messages: Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades.

9135:TMLHE
gene id: 9135:TMLHE
uniprot id: A0A8C9NUJ2
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

9135:IL1B
gene id: 9135:IL1B
uniprot id: A0A8C9NPB7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-1 family.
messages: Monomer.
messages: Secreted

9135:LOC103813448
gene id: 9135:LOC103813448
uniprot id: A0A8C9N3I1
names: Similarity
messages: Belongs to the peptidase A1 family.

9135:SIRT4
gene id: 9135:SIRT4
uniprot id: A0A8C9MLJ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Mitochondrion matrix
messages: NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues.

9135:SLC6A6
gene id: 9135:SLC6A6
uniprot id: A0A8C9MNZ3
uniprot id: A0A8C9MP89
uniprot id: A0A8C9MPS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A6 subfamily.
messages: Cell membrane
messages: Membrane

9135:TSPAN3
gene id: 9135:TSPAN3
uniprot id: A0A8C9NHE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9135:CCDC34
gene id: 9135:CCDC34
uniprot id: A0A8C9MZQ6
names: Subcellular Location Annotation
messages: flagellum

9135:ZDHHC21
gene id: 9135:ZDHHC21
uniprot id: A0A8C9L3D5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9135:CD28
gene id: 9135:CD28
uniprot id: A0A8C9KX70
names: Subcellular Location Annotation
messages: Membrane

9135:SST
gene id: 9135:SST
uniprot id: A0A8C9NLJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted

9135:FBLN5
gene id: 9135:FBLN5
uniprot id: A0A8C9N0L4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:PRIMPOL
gene id: 9135:PRIMPOL
uniprot id: A0A8C9N3J9
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

9135:RPS24
gene id: 9135:RPS24
uniprot id: A0A8C9MH29
uniprot id: A0A8C9MH98
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

9135:ATP7A
gene id: 9135:ATP7A
uniprot id: A0A8C9UHQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane
messages: trans-Golgi network membrane

9135:LOC103814334
gene id: 9135:LOC103814334
uniprot id: A0A8C9NH24
names: Similarity
messages: Belongs to the cytochrome P450 family.

9135:LOC103820451
gene id: 9135:LOC103820451
uniprot id: A0A8C9MKH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

9135:LOC103819062
gene id: 9135:LOC103819062
uniprot id: A0A8C9N772
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

9135:CPEB1
gene id: 9135:CPEB1
uniprot id: A0A8C9NQV3
uniprot id: A0A8C9NRK6
names: Similarity
messages: Belongs to the RRM CPEB family.

9135:RBFOX2
gene id: 9135:RBFOX2
uniprot id: A0A8C9MLD8
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

9135:CLIC5
gene id: 9135:CLIC5
uniprot id: A0A8C9UGA7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

9135:LOC103821673
gene id: 9135:LOC103821673
uniprot id: A0A8C9UE25
names: Domain
names: Function
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

9135:SPICE1
gene id: 9135:SPICE1
uniprot id: A0A8C9NBU5
names: Subcellular Location Annotation
messages: centriole
messages: spindle

9135:RAD51D
gene id: 9135:RAD51D
uniprot id: A0A8C9UAA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Nucleus

9135:LOC103819895
gene id: 9135:LOC103819895
uniprot id: A0A8C9MJ49
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

9135:SEC11A
gene id: 9135:SEC11A
uniprot id: A0A8C9UHS6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Component of the signal peptidase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane

9135:CA6
gene id: 9135:CA6
uniprot id: A0A8C9NTJ6
names: Caution
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reversible hydration of carbon dioxide.

9135:SLC25A30
gene id: 9135:SLC25A30
uniprot id: A0A8C9NKM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9135:CA10
gene id: 9135:CA10
uniprot id: A0A8C9NL91
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Does not have a catalytic activity.

9135:HOXA5
gene id: 9135:HOXA5
uniprot id: A0A8C9UHE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

9135:ALDH9A1
gene id: 9135:ALDH9A1
uniprot id: A0A8C9MFE5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

9135:PGLYRP2
gene id: 9135:PGLYRP2
uniprot id: A0A8C9NKB0
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

9135:TH
gene id: 9135:TH
uniprot id: A0A8C9U8B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
messages: axon
messages: perinuclear region

9135:LOC103813280
gene id: 9135:LOC103813280
uniprot id: A0A8C9MGA9
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

9135:MRPS10
gene id: 9135:MRPS10
uniprot id: A0A8C9MU20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Mitochondrion

9135:GTF2H2
gene id: 9135:GTF2H2
uniprot id: A0A8C9NGF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTF2H2 family.
messages: Nucleus

9135:AS3MT
gene id: 9135:AS3MT
uniprot id: A0A8C9NST9
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

9135:SV2B
gene id: 9135:SV2B
uniprot id: A0A8C9MUC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

9135:GPN1
gene id: 9135:GPN1
uniprot id: A0A8C9UGA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II.
messages: Cytoplasm
messages: Nucleus
messages: Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.

9135:YWHAH
gene id: 9135:YWHAH
uniprot id: A0A8C9MK73
names: Similarity
messages: Belongs to the 14-3-3 family.

9135:ELP4
gene id: 9135:ELP4
uniprot id: A0A8C9MX94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP4 family.
messages: Cytoplasm
messages: Nucleus

9135:KIF15
gene id: 9135:KIF15
uniprot id: A0A8C9KUJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-12 subfamily.
messages: spindle

9135:SFXN1
gene id: 9135:SFXN1
uniprot id: A0A8C9KTX8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

9135:CEPT1
gene id: 9135:CEPT1
uniprot id: A0A8C9MWP9
uniprot id: A0A8C9MWU4
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

9135:LOC103818791
gene id: 9135:LOC103818791
uniprot id: A0A8C9NEZ7
names: Similarity
messages: Belongs to the lipin family.

9135:PDRG1
gene id: 9135:PDRG1
uniprot id: A0A8C9NLE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Component of the PAQosome complex which is responsible for the biogenesis of several protein complexes and which consists of R2TP complex members RUVBL1, RUVBL2, RPAP3 and PIH1D1, URI complex members PFDN2, PFDN6, PDRG1, UXT and URI1 as well as ASDURF, POLR2E and DNAAF10/WDR92.
messages: Cytoplasm
messages: May play a role in chaperone-mediated protein folding.

9135:SLC35E2B
gene id: 9135:SLC35E2B
uniprot id: A0A8C9NRW0
names: Subcellular Location Annotation
messages: Membrane

9135:TMEM138
gene id: 9135:TMEM138
uniprot id: A0A8C9N5S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM138 family.
messages: Membrane
messages: Required for ciliogenesis.
messages: Vacuole membrane
messages: cilium

9135:SPTBN1
gene id: 9135:SPTBN1
uniprot id: A0A8C9NKS3
names: Similarity
messages: Belongs to the spectrin family.

9135:UPF3B
gene id: 9135:UPF3B
uniprot id: A0A8C9NXM9
names: Similarity
messages: Belongs to the RENT3 family.

9135:RPL23A
gene id: 9135:RPL23A
uniprot id: A0A8C9MYZ0
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

9135:BMPR2
gene id: 9135:BMPR2
uniprot id: A0A8C9MG31
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.

9135:ATAD1
gene id: 9135:ATAD1
uniprot id: A0A8C9MKU3
names: Similarity
messages: Belongs to the AAA ATPase family.

9135:LMNA
gene id: 9135:LMNA
uniprot id: A0A8C9NJ72
names: Similarity
messages: Belongs to the intermediate filament family.

9135:CDH5
gene id: 9135:CDH5
uniprot id: A0A8C9NA85
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

9135:LZTFL1
gene id: 9135:LZTFL1
uniprot id: A0A8C9MFW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LZTFL1 family.
messages: Cytoplasm
messages: Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function.
messages: Self-associates. Interacts with BBS9; the interaction mediates the association of LZTL1 with the BBsome complex and regulates BBSome ciliary trafficking.

9135:VCAM1
gene id: 9135:VCAM1
uniprot id: A0A8C9NEI2
names: Subcellular Location Annotation
messages: Cell membrane

9135:EXOC7
gene id: 9135:EXOC7
uniprot id: A0A8C9MHD4
uniprot id: A0A8C9MHH0
uniprot id: A0A8C9MHL0
uniprot id: A0A8C9MHM9
names: Function
names: Similarity
messages: Belongs to the EXO70 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

9135:PDE5A
gene id: 9135:PDE5A
uniprot id: A0A8C9KYA9
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9135:LOC103816605
gene id: 9135:LOC103816605
uniprot id: A0A8C9MLS6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9135:LOC103822566
gene id: 9135:LOC103822566
uniprot id: A0A8C9NPP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

9135:NSDHL
gene id: 9135:NSDHL
uniprot id: A0A8C9NTM8
names: Similarity
messages: Belongs to the 3-beta-HSD family.

9135:TNFRSF25
gene id: 9135:TNFRSF25
uniprot id: A0A8C9MGN9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:GFRA1
gene id: 9135:GFRA1
uniprot id: A0A8C9NMJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 2 molecules of GDNFR-alpha are thought to form a complex with the disulfide-linked GDNF dimer and with 2 molecules of RET.
messages: Belongs to the GDNFR family.
messages: Cell membrane
messages: Membrane
messages: Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor.

9135:TNFRSF11A
gene id: 9135:TNFRSF11A
uniprot id: A0A8C9MJA8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:NR1H3
gene id: 9135:NR1H3
uniprot id: A0A8C9MIR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

9135:RAF1
gene id: 9135:RAF1
uniprot id: A0A8C9NAW0
uniprot id: A0A8C9NB32
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

9135:LOC103819996
gene id: 9135:LOC103819996
uniprot id: A0A8C9MEB7
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Interacts with NCDN.
messages: Membrane

9135:LOC103822945
gene id: 9135:LOC103822945
uniprot id: A0A8C9U7Y1
names: Similarity
messages: Belongs to the FBPase class 1 family.

9135:CP
gene id: 9135:CP
uniprot id: A0A8C9N127
names: Similarity
messages: Belongs to the multicopper oxidase family.

9135:TRPV1
gene id: 9135:TRPV1
uniprot id: A0A8C9UE57
names: Subcellular Location Annotation
messages: Membrane

9135:A4GALT
gene id: 9135:A4GALT
uniprot id: A0A8C9N324
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 32 family.
messages: Golgi apparatus membrane

9135:MFN1
gene id: 9135:MFN1
uniprot id: A0A8C9NFQ7
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

9135:LMOD1
gene id: 9135:LMOD1
uniprot id: A0A8C9MXM3
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

9135:SLC17A5
gene id: 9135:SLC17A5
uniprot id: A0A8C9MYS2
names: Subcellular Location Annotation
messages: Membrane

9135:EMG1
gene id: 9135:EMG1
uniprot id: A0A8C9NMF6
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.

9135:IL10
gene id: 9135:IL10
uniprot id: A0A8C9UFB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

9135:EPHA7
gene id: 9135:EPHA7
uniprot id: A0A8C9L3C8
uniprot id: A0A8C9MF79
names: Subcellular Location Annotation
messages: Membrane

9135:NTAQ1
gene id: 9135:NTAQ1
uniprot id: A0A8C9MWY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NTAQ1 family.
messages: Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.
messages: Monomer.

9135:A2M
gene id: 9135:A2M
uniprot id: A0A8C9KP39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

9135:LOC103814146
gene id: 9135:LOC103814146
uniprot id: A0A8C9NVN0
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

9135:MED22
gene id: 9135:MED22
uniprot id: A0A8C9MK89
names: Function
names: Subcellular Location Annotation
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

9135:LOC103815260
gene id: 9135:LOC103815260
uniprot id: A0A8C9MFZ4
names: Similarity
messages: Belongs to the serpin family.

9135:SMIM18
gene id: 9135:SMIM18
uniprot id: A0A8C9U6A4
names: Subcellular Location Annotation
messages: Membrane

9135:FITM2
gene id: 9135:FITM2
uniprot id: A0A8C9NHJ3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9135:APOD
gene id: 9135:APOD
uniprot id: A0A8C9NS99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

9135:PDE6B
gene id: 9135:PDE6B
uniprot id: A0A8C9UFK3
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9135:AP3D1
gene id: 9135:AP3D1
uniprot id: A0A8C9MFF5
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

9135:GFOD2
gene id: 9135:GFOD2
uniprot id: A0A8C9MT22
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

9135:TUBB1
gene id: 9135:TUBB1
uniprot id: A0A8C9NS11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

9135:PDX1
gene id: 9135:PDX1
uniprot id: A0A8C9MTI6
names: Subcellular Location Annotation
messages: Nucleus

9135:NR1H4
gene id: 9135:NR1H4
uniprot id: A0A8C9MUG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
messages: Nucleus

9135:PKIA
gene id: 9135:PKIA
uniprot id: A0A8C9MFM4
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

9135:ARMC9
gene id: 9135:ARMC9
uniprot id: A0A8C9NMN2
uniprot id: A0A8C9NNK9
names: Subcellular Location Annotation
messages: centriole
messages: cilium
messages: cilium basal body

9135:GSX1
gene id: 9135:GSX1
uniprot id: A0A8C9MV57
names: Subcellular Location Annotation
messages: Nucleus

9135:ATOSA
gene id: 9135:ATOSA
uniprot id: A0A8C9L1J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATOS family.
messages: Nucleus

9135:CMC2
gene id: 9135:CMC2
uniprot id: A0A8C9MUM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion

9135:MYO1E
gene id: 9135:MYO1E
uniprot id: A0A8C9NW41
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

9135:GALNT3
gene id: 9135:GALNT3
uniprot id: A0A8C9NNY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9135:HSPB2
gene id: 9135:HSPB2
uniprot id: A0A8C9MZP6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

9135:DLL4
gene id: 9135:DLL4
uniprot id: A0A8C9MG65
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

9135:LOC103817611
gene id: 9135:LOC103817611
uniprot id: A0A8C9N1M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Cell membrane
messages: Membrane

9135:PRICKLE2
gene id: 9135:PRICKLE2
uniprot id: A0A8C9MVF7
uniprot id: A0A8C9UC21
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

9135:GJA5
gene id: 9135:GJA5
uniprot id: A0A8C9NAE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9135:GATM
gene id: 9135:GATM
uniprot id: A0A8C9MPG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the amidinotransferase family.
messages: Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine. Creatine plays a vital role in energy metabolism in muscle tissues. May play a role in embryonic and central nervous system development.
messages: Homodimer.
messages: Mitochondrion inner membrane

9135:NDP
gene id: 9135:NDP
uniprot id: A0A8C9NAV8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9135:ABCB9
gene id: 9135:ABCB9
uniprot id: A0A8C9N2K9
names: Subcellular Location Annotation
messages: Membrane

9135:TSEN15
gene id: 9135:TSEN15
uniprot id: A0A8C9NAN0
names: Similarity
messages: Belongs to the SEN15 family.

9135:SERPINB10
gene id: 9135:SERPINB10
uniprot id: A0A8C9MFK2
names: Similarity
messages: Belongs to the serpin family.

9135:TVP23A
gene id: 9135:TVP23A
uniprot id: A0A8C9UEK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane

9135:SLC35A5
gene id: 9135:SLC35A5
uniprot id: A0A8C9N476
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9135:FERMT1
gene id: 9135:FERMT1
uniprot id: A0A8C9UGB4
names: Similarity
messages: Belongs to the kindlin family.

9135:QRFPR
gene id: 9135:QRFPR
uniprot id: A0A8C9KYY6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9135:RBBP8
gene id: 9135:RBBP8
uniprot id: A0A8C9N7X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COM1/SAE2/CtIP family.
messages: Nucleus

9135:CRYAA
gene id: 9135:CRYAA
uniprot id: A0A8C9NAS2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

9135:CLRN2
gene id: 9135:CLRN2
uniprot id: A0A8C9L651
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

9135:GSTA1
gene id: 9135:GSTA1
uniprot id: A0A8C9NBA1
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

9135:MRPS7
gene id: 9135:MRPS7
uniprot id: A0A8C9KUT2
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

9135:RNF13
gene id: 9135:RNF13
uniprot id: A0A8C9N1L3
names: Subcellular Location Annotation
messages: Membrane

9135:GALNT15
gene id: 9135:GALNT15
uniprot id: A0A8C9NPY9
uniprot id: A0A8C9NQZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9135:EEF1A1
gene id: 9135:EEF1A1
uniprot id: A0A8C9UCA9
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

9135:NUDT12
gene id: 9135:NUDT12
uniprot id: A0A8C9UJ09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Cytoplasmic granule
messages: Peroxisome

9135:NCBP3
gene id: 9135:NCBP3
uniprot id: A0A8C9MVT3
names: Similarity
messages: Belongs to the NCBP3 family.

9135:LPAR4
gene id: 9135:LPAR4
uniprot id: A0A8C9KUN2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9135:DRD1
gene id: 9135:DRD1
uniprot id: A0A8C9UH54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9135:TACC2
gene id: 9135:TACC2
uniprot id: A0A8C9NJJ2
uniprot id: A0A8C9UGI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

9135:PDCD5
gene id: 9135:PDCD5
uniprot id: A0A8C9ML33
names: Similarity
messages: Belongs to the PDCD5 family.

9135:ING5
gene id: 9135:ING5
uniprot id: A0A8C9N0W5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

9135:LOC103827082
gene id: 9135:LOC103827082
uniprot id: A0A8C9N4H4
names: Function
names: Similarity
messages: Belongs to the apovitellenin family.
messages: Protein component of the very low density lipoprotein (VLDL) of egg-laying females. Potent lipoprotein lipase inhibitor, preventing the loss of triglycerides from VLDL on their way from the liver to the growing oocytes.

9135:TRAPPC3
gene id: 9135:TRAPPC3
uniprot id: A0A8C9NP10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Homodimer.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: cis-Golgi network

9135:LOC103813349
gene id: 9135:LOC103813349
uniprot id: A0A8C9UBC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9135:SLC45A1
gene id: 9135:SLC45A1
uniprot id: A0A8C9MH31
names: Subcellular Location Annotation
messages: Membrane

9135:ALX1
gene id: 9135:ALX1
uniprot id: A0A8C9MZF8
names: Subcellular Location Annotation
messages: Nucleus

9135:LOC103813337
gene id: 9135:LOC103813337
uniprot id: A0A8C9MUQ2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9135:RBM47
gene id: 9135:RBM47
uniprot id: A0A8C9MRH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM RBM47 family.
messages: Cytoplasm
messages: Nucleus

9135:NAALADL2
gene id: 9135:NAALADL2
uniprot id: A0A8C9NCI1
uniprot id: A0A8C9NE58
uniprot id: A0A8C9NF36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Membrane

9135:LOC103815742
gene id: 9135:LOC103815742
uniprot id: A0A8C9NAE4
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

9135:LOC103820475
gene id: 9135:LOC103820475
uniprot id: A0A8C9U9G2
names: Similarity
messages: Belongs to the aldo/keto reductase family.

9135:TRAPPC6B
gene id: 9135:TRAPPC6B
uniprot id: A0A8C9N504
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: cis-Golgi network

9135:AGPAT3
gene id: 9135:AGPAT3
uniprot id: A0A8C9NBM7
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

9135:HSDL1
gene id: 9135:HSDL1
uniprot id: A0A8C9MPY0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9135:DCT
gene id: 9135:DCT
uniprot id: A0A8C9NTR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane
messages: Membrane

9135:HOXA6
gene id: 9135:HOXA6
uniprot id: A0A8C9NR95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

9135:PDE8A
gene id: 9135:PDE8A
uniprot id: A0A8C9U869
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9135:SCG5
gene id: 9135:SCG5
uniprot id: A0A8C9NDZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 7B2 family.
messages: Secreted

9135:MTNR1A
gene id: 9135:MTNR1A
uniprot id: A0A8C9N6V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9135:NSRP1
gene id: 9135:NSRP1
uniprot id: A0A8C9N2L8
names: Similarity
messages: Belongs to the NSRP1 family.

9135:C2H5orf22
gene id: 9135:C2H5orf22
uniprot id: A0A8C9U549
names: Similarity
messages: Belongs to the UPF0489 family.

9135:NUF2
gene id: 9135:NUF2
uniprot id: A0A8C9MFH9
names: Similarity
messages: Belongs to the NUF2 family.

9135:PHTF2
gene id: 9135:PHTF2
uniprot id: A0A8C9UCI3
names: Subcellular Location Annotation
messages: Membrane

9135:NAPB
gene id: 9135:NAPB
uniprot id: A0A8C9NNZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

9135:LOC103827237
gene id: 9135:LOC103827237
uniprot id: A0A8C9U1H4
names: Subcellular Location Annotation
messages: Membrane

9135:PIK3R3
gene id: 9135:PIK3R3
uniprot id: A0A8C9MHV2
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

9135:STON1
gene id: 9135:STON1
uniprot id: A0A8C9NFM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Stoned B family.
messages: Cytoplasm
messages: May be involved in the endocytic machinery.

9135:ITM2B
gene id: 9135:ITM2B
uniprot id: A0A8C9UG42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

9135:FRRS1
gene id: 9135:FRRS1
uniprot id: A0A8C9NHB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRRS1 family.
messages: Membrane

9135:YPEL1
gene id: 9135:YPEL1
uniprot id: A0A8C9MMK0
names: Similarity
messages: Belongs to the yippee family.

9135:AP1S3
gene id: 9135:AP1S3
uniprot id: A0A8C9MGL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

9135:RPL9
gene id: 9135:RPL9
uniprot id: A0A8C9MRX5
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

9135:ISM2
gene id: 9135:ISM2
uniprot id: A0A8C9N3X4
names: Similarity
messages: Belongs to the isthmin family.

9135:EHHADH
gene id: 9135:EHHADH
uniprot id: A0A8C9MQV8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

9135:YTHDC1
gene id: 9135:YTHDC1
uniprot id: A0A8C9NDE1
uniprot id: A0A8C9NHH4
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

9135:SGPL1
gene id: 9135:SGPL1
uniprot id: A0A8C9NU65
names: Similarity
messages: Belongs to the group II decarboxylase family.

9135:KCNK5
gene id: 9135:KCNK5
uniprot id: A0A8C9N958
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

9135:LOC103821826
gene id: 9135:LOC103821826
uniprot id: A0A8C9N9M4
names: Similarity
messages: Belongs to the thioredoxin family.

9135:OSBPL10
gene id: 9135:OSBPL10
uniprot id: A0A8C9MDR6
names: Similarity
messages: Belongs to the OSBP family.

9135:EXOSC2
gene id: 9135:EXOSC2
uniprot id: A0A8C9MMX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP4 family.
messages: Cytoplasm

9135:PI4KA
gene id: 9135:PI4KA
uniprot id: A0A8C9MN23
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

9135:CHRM5
gene id: 9135:CHRM5
uniprot id: A0A8C9NBR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

9135:GHSR
gene id: 9135:GHSR
uniprot id: A0A8C9UES7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9135:LOC103827252
gene id: 9135:LOC103827252
uniprot id: A0A8C9MIN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

9135:DCAF13
gene id: 9135:DCAF13
uniprot id: A0A8C9MS41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DCAF13/WDSOF1 family.
messages: nucleolus

9135:CAPZA1
gene id: 9135:CAPZA1
uniprot id: A0A8C9NPM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

9135:GOSR1
gene id: 9135:GOSR1
uniprot id: A0A8C9N1Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GOSR1 family.
messages: Component of several multiprotein Golgi SNARE complexes.
messages: Golgi apparatus membrane
messages: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.
messages: Membrane

9135:YIPF1
gene id: 9135:YIPF1
uniprot id: A0A8C9MTV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Late endosome membrane
messages: Membrane
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

9135:LOC103821740
gene id: 9135:LOC103821740
uniprot id: A0A8C9MZE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gastrin/cholecystokinin family.
messages: Secreted

9135:SLC25A38
gene id: 9135:SLC25A38
uniprot id: A0A8C9L6H9
uniprot id: A0A8C9MF93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
messages: Membrane
messages: Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis.
messages: Mitochondrion inner membrane

9135:FAM210A
gene id: 9135:FAM210A
uniprot id: A0A8C9MZD3
names: Similarity
messages: Belongs to the LEA type 4 family.

9135:NOP14
gene id: 9135:NOP14
uniprot id: A0A8C9NRN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP14 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
messages: nucleolus

9135:MAS1
gene id: 9135:MAS1
uniprot id: A0A8C9UES2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9135:LITAF
gene id: 9135:LITAF
uniprot id: A0A8C9UEJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

9135:LOC103821610
gene id: 9135:LOC103821610
uniprot id: A0A8C9MWU1
names: Similarity
messages: Belongs to the intermediate filament family.

9135:TAC1
gene id: 9135:TAC1
uniprot id: A0A8C9NH33
uniprot id: A0A8C9NJA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted
messages: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.

9135:EVA1C
gene id: 9135:EVA1C
uniprot id: A0A8C9N346
names: Similarity
messages: Belongs to the EVA1 family.

9135:UTP15
gene id: 9135:UTP15
uniprot id: A0A8C9MMV6
names: Subcellular Location Annotation
messages: nucleolus

9135:ADGRG6
gene id: 9135:ADGRG6
uniprot id: A0A8C9NL42
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9135:PTPN21
gene id: 9135:PTPN21
uniprot id: A0A8C9MZQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

9135:RBP7
gene id: 9135:RBP7
uniprot id: A0A8C9NY26
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

9135:LOC103826086
gene id: 9135:LOC103826086
uniprot id: A0A8C9NQ14
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

9135:CLPS
gene id: 9135:CLPS
uniprot id: A0A8C9NLS9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.
messages: Enterostatin has a biological activity as a satiety signal.
messages: Forms a 1:1 stoichiometric complex with pancreatic lipase.
messages: Secreted

9135:PTGR2
gene id: 9135:PTGR2
uniprot id: A0A8C9NK55
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADP-dependent oxidoreductase L4BD family.
messages: Cytoplasm
messages: Monomer.

9135:FGD2
gene id: 9135:FGD2
uniprot id: A0A8C9NF04
names: Subcellular Location Annotation
messages: cytoskeleton

9135:SLCO1C1
gene id: 9135:SLCO1C1
uniprot id: A0A8C9MYD6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9135:C1H11orf54
gene id: 9135:C1H11orf54
uniprot id: A0A8C9MJR7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Exhibits ester hydrolase activity on the substrate p-nitrophenyl acetate.
messages: Monomer.
messages: Nucleus

9135:NT5C3A
gene id: 9135:NT5C3A
uniprot id: A0A8C9N6E4
uniprot id: A0A8C9N7J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

9135:CCT3
gene id: 9135:CCT3
uniprot id: A0A8C9N9G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

9135:MRPL41
gene id: 9135:MRPL41
uniprot id: A0A8C9N7Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL41 family.
messages: Mitochondrion

9135:LOC103817262
gene id: 9135:LOC103817262
uniprot id: A0A8C9NAH6
uniprot id: A0A8C9NAP1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
messages: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.

9135:TRPV3
gene id: 9135:TRPV3
uniprot id: A0A8C9N7Q6
names: Subcellular Location Annotation
messages: Membrane

9135:FLT1
gene id: 9135:FLT1
uniprot id: A0A8C9MTN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

9135:SPCS2
gene id: 9135:SPCS2
uniprot id: A0A8C9NGI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS2 family.
messages: Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site.
messages: Endoplasmic reticulum membrane
messages: Membrane

9135:PPFIBP2
gene id: 9135:PPFIBP2
uniprot id: A0A8C9MYJ5
uniprot id: A0A8C9MZX5
uniprot id: A0A8C9UCJ3
names: Similarity
messages: Belongs to the liprin family. Liprin-beta subfamily.

9135:OPA1
gene id: 9135:OPA1
uniprot id: A0A8C9NKR3
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane

9135:LOC103822944
gene id: 9135:LOC103822944
uniprot id: A0A8C9MME5
names: Similarity
messages: Belongs to the FBPase class 1 family.

9135:LBH
gene id: 9135:LBH
uniprot id: A0A8C9NRT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LBH family.
messages: Cytoplasm
messages: Nucleus
messages: Transcriptional activator.

9135:FAM234A
gene id: 9135:FAM234A
uniprot id: A0A8C9UFE4
names: Similarity
messages: Belongs to the FAM234 family.

9135:MFSD11
gene id: 9135:MFSD11
uniprot id: A0A8C9MIN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

9135:METTL16
gene id: 9135:METTL16
uniprot id: A0A8C9N6I2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: RNA N6-methyltransferase that methylates adenosine residues at the N(6) position of a subset of RNAs and is involved in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6-methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure.

9135:ADM
gene id: 9135:ADM
uniprot id: A0A8C9MZ35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adrenomedullin family.
messages: Secreted

9135:RSAD2
gene id: 9135:RSAD2
uniprot id: A0A8C9NAR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RSAD2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9135:CDKN1B
gene id: 9135:CDKN1B
uniprot id: A0A8C9N5F0
names: Similarity
messages: Belongs to the CDI family.

9135:PRDX6
gene id: 9135:PRDX6
uniprot id: A0A8C9NQQ2
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

9135:NUSAP1
gene id: 9135:NUSAP1
uniprot id: A0A8C9U398
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NUSAP family.
messages: Cytoplasm

9135:ACE
gene id: 9135:ACE
uniprot id: A0A8C9N255
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M2 family.
messages: Binds 2 Zn(2+) ions per subunit.

9135:TRAF5
gene id: 9135:TRAF5
uniprot id: A0A8C9MRM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

9135:NEK7
gene id: 9135:NEK7
uniprot id: A0A8C9NCC6
names: Similarity
messages: Belongs to the protein kinase superfamily.

9135:LOC103820232
gene id: 9135:LOC103820232
uniprot id: A0A8C9U6J3
names: Function
names: Similarity
messages: Belongs to the TYW1 family.
messages: Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis.

9135:HTRA3
gene id: 9135:HTRA3
uniprot id: A0A8C9NNT6
names: Similarity
messages: Belongs to the peptidase S1C family.

9135:SLC16A12
gene id: 9135:SLC16A12
uniprot id: A0A8C9NY27
names: Subcellular Location Annotation
messages: Membrane

9135:LOC103814830
gene id: 9135:LOC103814830
uniprot id: A0A8C9NA07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9135:SNRPC
gene id: 9135:SNRPC
uniprot id: A0A8C9NRR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the U1 small nuclear ribonucleoprotein C family.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. snrpc/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates E complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Nucleus
messages: U1 snRNP is composed of the 7 core Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins SNRNP70/U1-70K, SNRPA/U1-A and SNRPC/U1-C. SNRPC/U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA.

9135:CERS3
gene id: 9135:CERS3
uniprot id: A0A8C9N1H7
uniprot id: A0A8C9N2G6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

9135:OLFML3
gene id: 9135:OLFML3
uniprot id: A0A8C9NG25
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:ST3GAL1
gene id: 9135:ST3GAL1
uniprot id: A0A8C9N2P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9135:SPI1
gene id: 9135:SPI1
uniprot id: A0A8C9MIX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9135:NDUFB8
gene id: 9135:NDUFB8
uniprot id: A0A8C9NXZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB8 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9135:ATG2B
gene id: 9135:ATG2B
uniprot id: A0A8C9UC51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG2 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Preautophagosomal structure membrane

9135:PLA2G1B
gene id: 9135:PLA2G1B
uniprot id: A0A8C9MLQ2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

9135:CDCP2
gene id: 9135:CDCP2
uniprot id: A0A8C9MTP7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:FGD6
gene id: 9135:FGD6
uniprot id: A0A8C9MX89
names: Subcellular Location Annotation
messages: cytoskeleton

9135:SOAT1
gene id: 9135:SOAT1
uniprot id: A0A8C9N6G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

9135:TRIP13
gene id: 9135:TRIP13
uniprot id: A0A8C9UHD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. PCH2 subfamily.
messages: Nucleus
messages: Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways.

9135:PRPF3
gene id: 9135:PRPF3
uniprot id: A0A8C9NCQ7
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).

9135:SLC30A1
gene id: 9135:SLC30A1
uniprot id: A0A8C9MT67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

9135:AAMP
gene id: 9135:AAMP
uniprot id: A0A8C9UFW5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9135:LOC103815768
gene id: 9135:LOC103815768
uniprot id: A0A8C9NC39
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

9135:GEM
gene id: 9135:GEM
uniprot id: A0A8C9MI79
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

9135:HBS1L
gene id: 9135:HBS1L
uniprot id: A0A8C9NA56
names: Subcellular Location Annotation
messages: Cytoplasm

9135:PHACTR4
gene id: 9135:PHACTR4
uniprot id: A0A8C9UBY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.
messages: Cytoplasm
messages: Regulator of protein phosphatase 1 (PP1) required for neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development. Acts as an activator of PP1. During neural tube closure, localizes to the ventral neural tube and activates PP1, leading to down-regulate cell proliferation within cranial neural tissue and the neural retina. Also acts as a regulator of migration of enteric neural crest cells (ENCCs) by activating PP1, leading to repression of the integrin signaling through the rho/rock pathway.
messages: lamellipodium

9135:MKI67
gene id: 9135:MKI67
uniprot id: A0A8C9UEB4
names: Subcellular Location Annotation
messages: Nucleus

9135:ARL8A
gene id: 9135:ARL8A
uniprot id: A0A8C9MSR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

9135:ANKRD13A
gene id: 9135:ANKRD13A
uniprot id: A0A8C9MSG1
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

9135:CPD
gene id: 9135:CPD
uniprot id: A0A8C9N2A7
names: Similarity
messages: Belongs to the peptidase M14 family.

9135:STAC
gene id: 9135:STAC
uniprot id: A0A8C9N671
names: Subcellular Location Annotation
messages: sarcolemma

9135:CSNK1G3
gene id: 9135:CSNK1G3
uniprot id: A0A8C9MQ66
uniprot id: A0A8C9U808
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

9135:MBP
gene id: 9135:MBP
uniprot id: A0A8C9MXZ6
uniprot id: A0A8C9MYK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin basic protein family.
messages: Myelin membrane

9135:SEMA5A
gene id: 9135:SEMA5A
uniprot id: A0A8C9MMF1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:MYOF
gene id: 9135:MYOF
uniprot id: A0A8C9NXH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferlin family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

9135:DYNC2H1
gene id: 9135:DYNC2H1
uniprot id: A0A8C9MKM2
names: Similarity
messages: Belongs to the dynein heavy chain family.

9135:LOC103820946
gene id: 9135:LOC103820946
uniprot id: A0A8C9U2V4
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

9135:PCSK2
gene id: 9135:PCSK2
uniprot id: A0A8C9MWI5
uniprot id: A0A8C9MZM5
names: Similarity
messages: Belongs to the peptidase S8 family.

9135:LOC103826085
gene id: 9135:LOC103826085
uniprot id: A0A8C9NNV7
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

9135:PGD
gene id: 9135:PGD
uniprot id: A0A8C9NXZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

9135:FABP6
gene id: 9135:FABP6
uniprot id: A0A8C9KTL7
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

9135:OAT
gene id: 9135:OAT
uniprot id: A0A8C9UFV2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

9135:NDUFS5
gene id: 9135:NDUFS5
uniprot id: A0A8C9MQA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS5 subunit family.
messages: Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.
messages: Membrane
messages: Mitochondrion inner membrane

9135:LCA5
gene id: 9135:LCA5
uniprot id: A0A8C9MN30
names: Similarity
messages: Belongs to the LCA5 family.

9135:LOC103824423
gene id: 9135:LOC103824423
uniprot id: A0A8C9U905
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:EXT1
gene id: 9135:EXT1
uniprot id: A0A8C9UBS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

9135:FGF23
gene id: 9135:FGF23
uniprot id: A0A8C9N5I5
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9135:DDO
gene id: 9135:DDO
uniprot id: A0A8C9L4P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

9135:MCM2
gene id: 9135:MCM2
uniprot id: A0A8C9MP17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

9135:SGK2
gene id: 9135:SGK2
uniprot id: A0A8C9NEP0
uniprot id: A0A8C9NF16
names: Similarity
messages: Belongs to the protein kinase superfamily.

9135:THUMPD2
gene id: 9135:THUMPD2
uniprot id: A0A8C9L4L7
names: Similarity
messages: Belongs to the methyltransferase superfamily.

9135:RBP2
gene id: 9135:RBP2
uniprot id: A0A8C9N0Q9
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

9135:EXTL3
gene id: 9135:EXTL3
uniprot id: A0A8C9NPD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

9135:MID2
gene id: 9135:MID2
uniprot id: A0A8C9UI08
names: Subcellular Location Annotation
messages: cytoskeleton

9135:ALG14
gene id: 9135:ALG14
uniprot id: A0A8C9NDQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG14 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane

9135:LOC103823654
gene id: 9135:LOC103823654
uniprot id: A0A8C9N828
names: Similarity
messages: Belongs to the CBP3 family.

9135:INTS8
gene id: 9135:INTS8
uniprot id: A0A8C9MJN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 8 family.
messages: Nucleus

9135:TIPIN
gene id: 9135:TIPIN
uniprot id: A0A8C9N9H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSM3 family.
messages: Nucleus
messages: Plays an important role in the control of DNA replication and the maintenance of replication fork stability.

9135:UROD
gene id: 9135:UROD
uniprot id: A0A8C9KRZ7
names: Similarity
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Homodimer.

9135:FIGN
gene id: 9135:FIGN
uniprot id: A0A8C9UHB8
names: Similarity
messages: Belongs to the AAA ATPase family.

9135:DNAJB14
gene id: 9135:DNAJB14
uniprot id: A0A8C9NLD0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9135:RHO
gene id: 9135:RHO
uniprot id: A0A8C9NTZ8
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Contains one covalently linked retinal chromophore.
messages: Membrane

9135:MITF
gene id: 9135:MITF
uniprot id: A0A8C9UBY8
uniprot id: A0A8C9UCI7
uniprot id: A0A8C9UCI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

9135:MYOD1
gene id: 9135:MYOD1
uniprot id: A0A8C9MPG0
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

9135:LOC103824734
gene id: 9135:LOC103824734
uniprot id: A0A8C9NT99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

9135:PIK3CG
gene id: 9135:PIK3CG
uniprot id: A0A8C9MWE7
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

9135:LOC108961169
gene id: 9135:LOC108961169
uniprot id: A0A8C9MZ61
names: Similarity
messages: Belongs to the CD225/Dispanin family.

9135:PTS
gene id: 9135:PTS
uniprot id: A0A8C9UBP3
names: Function
names: Similarity
messages: Belongs to the PTPS family.
messages: Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin.

9135:HOPX
gene id: 9135:HOPX
uniprot id: A0A8C9NE66
names: Subcellular Location Annotation
messages: Nucleus

9135:VIM
gene id: 9135:VIM
uniprot id: A0A8C9UEG7
names: Similarity
messages: Belongs to the intermediate filament family.

9135:LOC103819581
gene id: 9135:LOC103819581
uniprot id: A0A8C9N1A2
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

9135:MALL
gene id: 9135:MALL
uniprot id: A0A8C9NKC5
names: Subcellular Location Annotation
messages: Membrane

9135:C9H3orf70
gene id: 9135:C9H3orf70
uniprot id: A0A8C9MQJ9
names: Similarity
messages: Belongs to the UPF0524 family.

9135:RGMB
gene id: 9135:RGMB
uniprot id: A0A8C9UB84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

9135:ALDOC
gene id: 9135:ALDOC
uniprot id: A0A8C9MXC9
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

9135:MAB21L1
gene id: 9135:MAB21L1
uniprot id: A0A8C9NCT2
names: Similarity
messages: Belongs to the mab-21 family.

9135:LOC103812823
gene id: 9135:LOC103812823
uniprot id: A0A8C9NER4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

9135:PSMD1
gene id: 9135:PSMD1
uniprot id: A0A8C9NN88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S1 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

9135:GGACT
gene id: 9135:GGACT
uniprot id: A0A8C9NRF1
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the formation of 5-oxo-L-proline from L-gamma-glutamyl-L-epsilon-lysine.

9135:BFSP1
gene id: 9135:BFSP1
uniprot id: A0A8C9MZN1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: cell cortex
messages: cytoskeleton

9135:JPT1
gene id: 9135:JPT1
uniprot id: A0A8C9KUV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

9135:C1S
gene id: 9135:C1S
uniprot id: A0A8C9NN97
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:MAPK1
gene id: 9135:MAPK1
uniprot id: A0A8C9MN39
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

9135:IL7R
gene id: 9135:IL7R
uniprot id: A0A8C9MZI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Membrane

9135:DNASE1L3
gene id: 9135:DNASE1L3
uniprot id: A0A8C9MKQ2
names: Similarity
messages: Belongs to the DNase I family.

9135:LOC103812473
gene id: 9135:LOC103812473
uniprot id: A0A8C9NPP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

9135:CMAS
gene id: 9135:CMAS
uniprot id: A0A8C9N3Q3
names: Similarity
messages: Belongs to the CMP-NeuNAc synthase family.

9135:SAMM50
gene id: 9135:SAMM50
uniprot id: A0A8C9MYL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAM50/omp85 family.
messages: Mitochondrion outer membrane

9135:NUP133
gene id: 9135:NUP133
uniprot id: A0A8C9MJK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin Nup133 family.
messages: nuclear pore complex

9135:PTGR3
gene id: 9135:PTGR3
uniprot id: A0A8C9MY45
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

9135:RELL1
gene id: 9135:RELL1
uniprot id: A0A8C9U9I9
names: Similarity
messages: Belongs to the RELT family.

9135:LOC103813931
gene id: 9135:LOC103813931
uniprot id: A0A8C9UIA7
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

9135:LOC103826448
gene id: 9135:LOC103826448
uniprot id: A0A8C9MW60
names: Similarity
messages: Belongs to the serpin family.

9135:LOC103817388
gene id: 9135:LOC103817388
uniprot id: A0A8C9L3S5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCRQ/QCR8 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 11 subunits. The complex is composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein UQCRFS1, 2 core protein subunits UQCRC1/QCR1 and UQCRC2/QCR2, and 6 low-molecular weight protein subunits UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and subunit 9, the cleavage product of Rieske protein UQCRFS1. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and cytochrome c oxidase (complex IV, CIV), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)). Interacts with UQCC6.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

9135:KIF25
gene id: 9135:KIF25
uniprot id: A0A8C9U3Y0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9135:SLC6A14
gene id: 9135:SLC6A14
uniprot id: A0A8C9UIH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

9135:ABCA1
gene id: 9135:ABCA1
uniprot id: A0A8C9NKD9
names: Subcellular Location Annotation
messages: Membrane

9135:NEUROD6
gene id: 9135:NEUROD6
uniprot id: A0A8C9N6C0
names: Subcellular Location Annotation
messages: Nucleus

9135:DLGAP5
gene id: 9135:DLGAP5
uniprot id: A0A8C9MFU2
names: Similarity
messages: Belongs to the SAPAP family.

9135:SESN1
gene id: 9135:SESN1
uniprot id: A0A8C9L1I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

9135:LOC103813439
gene id: 9135:LOC103813439
uniprot id: A0A8C9UCK6
names: Similarity
messages: Belongs to the CRISP family.

9135:L3HYPDH
gene id: 9135:L3HYPDH
uniprot id: A0A8C9MT58
names: Similarity
messages: Belongs to the proline racemase family.

9135:LGI1
gene id: 9135:LGI1
uniprot id: A0A8C9NVE2
names: Subcellular Location Annotation
messages: Secreted

9135:APIP
gene id: 9135:APIP
uniprot id: A0A8C9MK54
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aldolase class II family. Adducin subfamily.
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis.
messages: Cytoplasm

9135:LOC103826869
gene id: 9135:LOC103826869
uniprot id: A0A8C9MV82
names: Similarity
messages: Belongs to the SEC6 family.

9135:PGAM1
gene id: 9135:PGAM1
uniprot id: A0A8C9NRX6
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

9135:DERL1
gene id: 9135:DERL1
uniprot id: A0A8C9MXY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Membrane

9135:TBL1X
gene id: 9135:TBL1X
uniprot id: A0A8C9NG09
uniprot id: A0A8C9NHJ7
names: Similarity
messages: Belongs to the WD repeat EBI family.

9135:TRPC4
gene id: 9135:TRPC4
uniprot id: A0A8C9UFT4
names: Subcellular Location Annotation
messages: Membrane

9135:ZDHHC12
gene id: 9135:ZDHHC12
uniprot id: A0A8C9MQ74
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9135:RTF2
gene id: 9135:RTF2
uniprot id: A0A8C9NSG8
names: Similarity
messages: Belongs to the rtf2 family.

9135:DLK2
gene id: 9135:DLK2
uniprot id: A0A8C9NCJ2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:LOC103813316
gene id: 9135:LOC103813316
uniprot id: A0A8C9MGD6
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

9135:ARHGEF3
gene id: 9135:ARHGEF3
uniprot id: A0A8C9MG03
names: Function
names: Subcellular Location Annotation
messages: Acts as guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases.
messages: Cytoplasm

9135:TSPAN9
gene id: 9135:TSPAN9
uniprot id: A0A8C9UH05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9135:DSCC1
gene id: 9135:DSCC1
uniprot id: A0A8C9MX56
names: Similarity
messages: Belongs to the DCC1 family.

9135:LOC103816795
gene id: 9135:LOC103816795
uniprot id: A0A8C9MKV9
names: Similarity
messages: Belongs to the BtpA family.

9135:GNG7
gene id: 9135:GNG7
uniprot id: A0A8C9MXG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

9135:LOC103814993
gene id: 9135:LOC103814993
uniprot id: A0A8C9MIJ3
names: Similarity
messages: Belongs to the amidase family.

9135:WNT10A
gene id: 9135:WNT10A
uniprot id: A0A8C9UFN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9135:TLL1
gene id: 9135:TLL1
uniprot id: A0A8C9N8A8
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:ABCG1
gene id: 9135:ABCG1
uniprot id: A0A8C9NA09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

9135:LOC103821128
gene id: 9135:LOC103821128
uniprot id: A0A8C9N641
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

9135:CCK
gene id: 9135:CCK
uniprot id: A0A8C9L4D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gastrin/cholecystokinin family.
messages: Secreted

9135:MAPK9
gene id: 9135:MAPK9
uniprot id: A0A8C9N8J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

9135:RPN1
gene id: 9135:RPN1
uniprot id: A0A8C9MMN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

9135:CAMK1
gene id: 9135:CAMK1
uniprot id: A0A8C9MR74
names: Similarity
messages: Belongs to the protein kinase superfamily.

9135:TPRA1
gene id: 9135:TPRA1
uniprot id: A0A8C9MND0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0359 family.
messages: Membrane

9135:UBE2E2
gene id: 9135:UBE2E2
uniprot id: A0A8C9NQY1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9135:SLC10A2
gene id: 9135:SLC10A2
uniprot id: A0A8C9NV12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

9135:GPR171
gene id: 9135:GPR171
uniprot id: A0A8C9UD00
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9135:BCR
gene id: 9135:BCR
uniprot id: A0A8C9MK42
uniprot id: A0A8C9U6L7
names: Subcellular Location Annotation
messages: Synapse
messages: axon
messages: dendritic spine

9135:TM7SF3
gene id: 9135:TM7SF3
uniprot id: A0A8C9N5V2
names: Subcellular Location Annotation
messages: Membrane

9135:ID3
gene id: 9135:ID3
uniprot id: A0A8C9N197
names: Subcellular Location Annotation
messages: Nucleus

9135:ABCC1
gene id: 9135:ABCC1
uniprot id: A0A8C9NC41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

9135:STK38L
gene id: 9135:STK38L
uniprot id: A0A8C9N4S9
names: Similarity
messages: Belongs to the protein kinase superfamily.

9135:POLL
gene id: 9135:POLL
uniprot id: A0A8C9NT63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Cytoplasm
messages: Nucleus

9135:CCNB3
gene id: 9135:CCNB3
uniprot id: A0A8C9NS03
names: Similarity
messages: Belongs to the cyclin family.

9135:BRCA1
gene id: 9135:BRCA1
uniprot id: A0A8C9MU06
names: Subcellular Location Annotation
messages: Chromosome
messages: Cytoplasm
messages: Nucleus

9135:P2RY13
gene id: 9135:P2RY13
uniprot id: A0A8C9N2G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9135:SLC16A5
gene id: 9135:SLC16A5
uniprot id: A0A8C9KV98
names: Subcellular Location Annotation
messages: Membrane

9135:KCNK9
gene id: 9135:KCNK9
uniprot id: A0A8C9MZR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane
messages: pH-dependent, voltage-insensitive, background potassium channel protein.

9135:ABCB1
gene id: 9135:ABCB1
uniprot id: A0A8C9NBQ8
names: Subcellular Location Annotation
messages: Membrane

9135:MRPL15
gene id: 9135:MRPL15
uniprot id: A0A8C9NG24
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

9135:CLDN23
gene id: 9135:CLDN23
uniprot id: A0A8C9UEV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

9135:LOC103824242
gene id: 9135:LOC103824242
uniprot id: A0A8C9NVN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tango11 family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Peroxisome
messages: Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface.

9135:TAT
gene id: 9135:TAT
uniprot id: A0A8C9N6L9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.

9135:NHP2
gene id: 9135:NHP2
uniprot id: A0A8C9L183
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

9135:HNF4A
gene id: 9135:HNF4A
uniprot id: A0A8C9UFY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9135:MLN
gene id: 9135:MLN
uniprot id: A0A8C9NQ26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the motilin family.
messages: Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle.
messages: Secreted

9135:P4HA2
gene id: 9135:P4HA2
uniprot id: A0A8C9N8R1
uniprot id: A0A8C9UDY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

9135:LOC103822464
gene id: 9135:LOC103822464
uniprot id: A0A8C9NE77
names: Similarity
messages: Belongs to the peptidase M14 family.

9135:LOC103812310
gene id: 9135:LOC103812310
uniprot id: A0A8C9NVC3
names: Similarity
messages: Belongs to the sulfatase family.

9135:HPSE
gene id: 9135:HPSE
uniprot id: A0A8C9NKM6
names: Similarity
messages: Belongs to the glycosyl hydrolase 79 family.

9135:LOC103817832
gene id: 9135:LOC103817832
uniprot id: A0A8C9MZJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

9135:LHFPL4
gene id: 9135:LHFPL4
uniprot id: A0A8C9MPV1
names: Subcellular Location Annotation
messages: Membrane

9135:LOC103826968
gene id: 9135:LOC103826968
uniprot id: A0A8C9UG41
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

9135:IL4I1
gene id: 9135:IL4I1
uniprot id: A0A8C9MQW3
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

9135:LOC103813955
gene id: 9135:LOC103813955
uniprot id: A0A8C9NYD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-microseminoprotein family.
messages: Secreted

9135:EDEM2
gene id: 9135:EDEM2
uniprot id: A0A8C9N1B8
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

9135:SERINC1
gene id: 9135:SERINC1
uniprot id: A0A8C9NM80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

9135:SAR1B
gene id: 9135:SAR1B
uniprot id: A0A8C9UE12
names: Similarity
messages: Belongs to the small GTPase superfamily. SAR1 family.

9135:WDR35
gene id: 9135:WDR35
uniprot id: A0A8C9NJ09
names: Subcellular Location Annotation
messages: centrosome
messages: cilium basal body

9135:LACTB2
gene id: 9135:LACTB2
uniprot id: A0A8C9KY01
names: Function
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.

9135:DLC1
gene id: 9135:DLC1
uniprot id: A0A8C9N3T8
names: Subcellular Location Annotation
messages: Cytoplasm

9135:XDH
gene id: 9135:XDH
uniprot id: A0A8C9NP60
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Peroxisome

9135:DLX5
gene id: 9135:DLX5
uniprot id: A0A8C9UG28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

9135:NUP93
gene id: 9135:NUP93
uniprot id: A0A8C9MQN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin interacting component (NIC) family.
messages: Nucleus membrane
messages: Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance.
messages: nuclear pore complex

9135:INTS14
gene id: 9135:INTS14
uniprot id: A0A8C9N7S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INTS14 family.
messages: Nucleus
messages: Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.

9135:LOC103827253
gene id: 9135:LOC103827253
uniprot id: A0A8C9MIL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

9135:RPP14
gene id: 9135:RPP14
uniprot id: A0A8C9MRE7
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.

9135:HPS5
gene id: 9135:HPS5
uniprot id: A0A8C9U929
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPS5 family.
messages: Component of the biogenesis of lysosome-related organelles complex-2 (or BLOC2) composed of HPS3, HPS5 and HPS6.
messages: May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.
messages: cytosol

9135:VPS36
gene id: 9135:VPS36
uniprot id: A0A8C9ND20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS36 family.
messages: Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).
messages: Cytoplasm
messages: Endosome

9135:IL13RA1
gene id: 9135:IL13RA1
uniprot id: A0A8C9NYJ5
names: Subcellular Location Annotation
messages: Membrane

9135:SH3BGRL
gene id: 9135:SH3BGRL
uniprot id: A0A8C9MGQ7
names: Similarity
messages: Belongs to the SH3BGR family.

9135:TTC39C
gene id: 9135:TTC39C
uniprot id: A0A8C9NBJ3
names: Similarity
messages: Belongs to the TTC39 family.

9135:STMN3
gene id: 9135:STMN3
uniprot id: A0A8C9NNK2
names: Similarity
messages: Belongs to the stathmin family.

9135:CAPN6
gene id: 9135:CAPN6
uniprot id: A0A8C9NSX7
names: Similarity
messages: Belongs to the peptidase C2 family.

9135:DDI2
gene id: 9135:DDI2
uniprot id: A0A8C9MNC1
names: Similarity
messages: Belongs to the DDI1 family.

9135:GOSR2
gene id: 9135:GOSR2
uniprot id: A0A8C9N3D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOSR2 family.
messages: Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
messages: Membrane

9135:CXCR5
gene id: 9135:CXCR5
uniprot id: A0A8C9NXU0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9135:PDE6C
gene id: 9135:PDE6C
uniprot id: A0A8C9UIP1
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9135:ZNF706
gene id: 9135:ZNF706
uniprot id: A0A8C9MML8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9135:WNT7B
gene id: 9135:WNT7B
uniprot id: A0A8C9MHR0
uniprot id: A0A8C9MI34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9135:FAM3D
gene id: 9135:FAM3D
uniprot id: A0A8C9MUC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

9135:RAB19
gene id: 9135:RAB19
uniprot id: A0A8C9UD62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane

9135:EBF2
gene id: 9135:EBF2
uniprot id: A0A8C9NXN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

9135:LOC103819513
gene id: 9135:LOC103819513
uniprot id: A0A8C9KSC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Has antiviral activities.
messages: Secreted

9135:CEBPZ
gene id: 9135:CEBPZ
uniprot id: A0A8C9N9V7
names: Similarity
messages: Belongs to the CBF/MAK21 family.

9135:ZWILCH
gene id: 9135:ZWILCH
uniprot id: A0A8C9N820
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZWILCH family.
messages: Component of the RZZ complex.
messages: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex.
messages: kinetochore

9135:S1PR1
gene id: 9135:S1PR1
uniprot id: A0A8C9NCB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9135:MPPE1
gene id: 9135:MPPE1
uniprot id: A0A8C9UCL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallophosphoesterase superfamily. MPPE1 family.
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins.
messages: cis-Golgi network membrane

9135:POLR3F
gene id: 9135:POLR3F
uniprot id: A0A8C9NDN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

9135:CASTOR2
gene id: 9135:CASTOR2
uniprot id: A0A8C9N2W7
names: Similarity
messages: Belongs to the GATS family.

9135:LOC103819907
gene id: 9135:LOC103819907
uniprot id: A0A8C9MK22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiA prenyltransferase family.
messages: Converts protoheme IX and farnesyl diphosphate to heme O.
messages: Membrane
messages: Mitochondrion membrane

9135:PRKCZ
gene id: 9135:PRKCZ
uniprot id: A0A8C9UJ11
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

9135:CMC4
gene id: 9135:CMC4
uniprot id: A0A8C9NQL3
uniprot id: A0A8C9UI77
names: Similarity
messages: Belongs to the CMC4 family.

9135:LOC103812472
gene id: 9135:LOC103812472
uniprot id: A0A8C9NM22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

9135:DDOST
gene id: 9135:DDOST
uniprot id: A0A8C9MMF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDOST 48 kDa subunit family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).

9135:OPTN
gene id: 9135:OPTN
uniprot id: A0A8C9N4X2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Golgi apparatus
messages: May act by regulating membrane trafficking and cellular morphogenesis.
messages: Recycling endosome
messages: autophagosome
messages: perinuclear region
messages: trans-Golgi network

9135:DNAJB12
gene id: 9135:DNAJB12
uniprot id: A0A8C9NSH8
names: Subcellular Location Annotation
messages: Membrane

9135:C9
gene id: 9135:C9
uniprot id: A0A8C9MYX6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9135:MPG
gene id: 9135:MPG
uniprot id: A0A8C9UFB9
names: Function
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.
messages: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.

9135:SERPINF2
gene id: 9135:SERPINF2
uniprot id: A0A8C9MUW1
names: Similarity
messages: Belongs to the serpin family.

9135:TMPRSS6
gene id: 9135:TMPRSS6
uniprot id: A0A8C9MLL9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9135:KCNJ5
gene id: 9135:KCNJ5
uniprot id: A0A8C9NY90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ5 subfamily.
messages: Membrane

9135:LOC103823464
gene id: 9135:LOC103823464
uniprot id: A0A8C9MMK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

9135:LOC108962310
gene id: 9135:LOC108962310
uniprot id: A0A8C9N759
names: Similarity
messages: Belongs to the cytochrome P450 family.

9135:GPATCH11
gene id: 9135:GPATCH11
uniprot id: A0A8C9NDR0
names: Similarity
messages: Belongs to the GPATCH11 family.

9135:POPDC2
gene id: 9135:POPDC2
uniprot id: A0A8C9N5S1
names: Similarity
messages: Belongs to the popeye family.

9135:GINS1
gene id: 9135:GINS1
uniprot id: A0A8C9MEU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS1/PSF1 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus
messages: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.

9135:CDS1
gene id: 9135:CDS1
uniprot id: A0A8C9NPJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Membrane

9135:LOC103816009
gene id: 9135:LOC103816009
uniprot id: A0A8C9MPK2
names: Similarity
messages: Belongs to the cytochrome P450 family.

9135:LOC103822274
gene id: 9135:LOC103822274
uniprot id: A0A8C9N6W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic cobalamin transport proteins family.
messages: Secreted

9135:BLCAP
gene id: 9135:BLCAP
uniprot id: A0A8C9NHQ1
names: Similarity
messages: Belongs to the BLCAP family.

9135:RAG1
gene id: 9135:RAG1
uniprot id: A0A8C9MJX4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAG1 family.
messages: Binds 1 divalent metal cation per subunit. Mg(2+) or Mn(2+).
messages: Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities. DNA cleavage occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the phosphodiester bond on the opposite strand in a direct transesterification reaction, thereby creating 4 DNA ends: 2 hairpin coding ends and 2 blunt, 5'-phosphorylated ends.
messages: Homodimer.
messages: Nucleus
messages: The NBD (nonamer binding) DNA-binding domain mediates the specific binding to the nonamer RSS motif by forming a tightly interwoven homodimer that binds and synapses 2 nonamer elements, with each NBD making contact with both DNA molecules. Each RSS is composed of well-conserved heptamer (consensus 5'-CACAGTG-3') and nonamer (consensus 5'-ACAAAAACC-3') sequences separated by a spacer of either 12 bp or 23 bp.

9135:TMEM9
gene id: 9135:TMEM9
uniprot id: A0A8C9MX78
names: Similarity
messages: Belongs to the TMEM9 family.

9135:CNOT8
gene id: 9135:CNOT8
uniprot id: A0A8C9NIP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

9135:SPIC
gene id: 9135:SPIC
uniprot id: A0A8C9N975
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9135:TAF4
gene id: 9135:TAF4
uniprot id: A0A8C9NP79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Nucleus

9135:MRPL53
gene id: 9135:MRPL53
uniprot id: A0A8C9MG06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL53 family.
messages: Mitochondrion

9135:MVB12B
gene id: 9135:MVB12B
uniprot id: A0A8C9NTX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MVB12 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

9135:LOC103823463
gene id: 9135:LOC103823463
uniprot id: A0A8C9MNG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

9135:CACNG2
gene id: 9135:CACNG2
uniprot id: A0A8C9ML76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

9135:RNF152
gene id: 9135:RNF152
uniprot id: A0A8C9MG59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNF152 family.
messages: Lysosome membrane
messages: Membrane

9135:LOC103814121
gene id: 9135:LOC103814121
uniprot id: A0A8C9NP09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

9135:LYZ
gene id: 9135:LYZ
uniprot id: A0A8C9L3S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 22 family.
messages: Secreted

9135:LOC103826153
gene id: 9135:LOC103826153
uniprot id: A0A8C9MVL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFI6/IFI27 family.
messages: Membrane

9135:TACR3
gene id: 9135:TACR3
uniprot id: A0A8C9NGA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9135:LOC103825461
gene id: 9135:LOC103825461
uniprot id: A0A8C9UD57
names: Similarity
messages: Belongs to the cytochrome P450 family.

9135:LACC1
gene id: 9135:LACC1
uniprot id: A0A8C9NHT1
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

9135:PAPSS2
gene id: 9135:PAPSS2
uniprot id: A0A8C9MKT4
names: Similarity
messages: In the C-terminal section; belongs to the sulfate adenylyltransferase family.
messages: In the N-terminal section; belongs to the APS kinase family.

9135:FAM149B1
gene id: 9135:FAM149B1
uniprot id: A0A8C9MMJ8
uniprot id: A0A8C9MMV1
names: Similarity
messages: Belongs to the FAM149 family.

9135:P2RY2
gene id: 9135:P2RY2
uniprot id: A0A8C9L279
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9135:CCNC
gene id: 9135:CCNC
uniprot id: A0A8C9KVJ8
names: Similarity
messages: Belongs to the cyclin family.

9135:LOC103812493
gene id: 9135:LOC103812493
uniprot id: A0A8C9MEV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

9135:PLCB2
gene id: 9135:PLCB2
uniprot id: A0A8C9NBD0
names: Cofactor
names: Function
messages: Binds 1 Ca(2+) ion per subunit.
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

9135:PSMG1
gene id: 9135:PSMG1
uniprot id: A0A8C9N732
names: Similarity
messages: Belongs to the PSMG1 family.

9135:ATP7B
gene id: 9135:ATP7B
uniprot id: A0A8C9NF85
uniprot id: A0A8C9NGQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane
messages: trans-Golgi network membrane

9135:STAB2
gene id: 9135:STAB2
uniprot id: A0A8C9N6D6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9135:PLA2G4F
gene id: 9135:PLA2G4F
uniprot id: A0A8C9KRE1
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

9135:USP38
gene id: 9135:USP38
uniprot id: A0A8C9NE16
names: Similarity
messages: Belongs to the peptidase C19 family.

9135:CNN2
gene id: 9135:CNN2
uniprot id: A0A8C9MU28
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

9135:PLA2R1
gene id: 9135:PLA2R1
uniprot id: A0A8C9NMA9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:STC1
gene id: 9135:STC1
uniprot id: A0A8C9NW69
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.

9135:TSNAX
gene id: 9135:TSNAX
uniprot id: A0A8C9MJF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the translin family.
messages: Nucleus

9135:LHPP
gene id: 9135:LHPP
uniprot id: A0A8C9NJM2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

9135:CNOT10
gene id: 9135:CNOT10
uniprot id: A0A8C9KRF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT10 family.
messages: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.
messages: Cytoplasm
messages: Nucleus

9135:LOC103817382
gene id: 9135:LOC103817382
uniprot id: A0A8C9UER8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Microsome membrane

9135:AMFR
gene id: 9135:AMFR
uniprot id: A0A8C9MP75
names: Subcellular Location Annotation
messages: Membrane

9135:USP15
gene id: 9135:USP15
uniprot id: A0A8C9L2N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Nucleus

9135:TRIAP1
gene id: 9135:TRIAP1
uniprot id: A0A8C9MKY7
names: Similarity
messages: Belongs to the TRIAP1/MDM35 family.

9135:CHFR
gene id: 9135:CHFR
uniprot id: A0A8C9MNP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CHFR family.
messages: PML body

9135:YIPF7
gene id: 9135:YIPF7
uniprot id: A0A8C9UC25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

9135:FOXL2
gene id: 9135:FOXL2
uniprot id: A0A8C9NW66
names: Subcellular Location Annotation
messages: Nucleus

9135:THOC5
gene id: 9135:THOC5
uniprot id: A0A8C9KY41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC5 family.
messages: Nucleus

9135:CPT1A
gene id: 9135:CPT1A
uniprot id: A0A8C9U6P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

9135:AHSA2P
gene id: 9135:AHSA2P
uniprot id: A0A8C9NGE4
names: Similarity
messages: Belongs to the AHA1 family.

9135:FUT9
gene id: 9135:FUT9
uniprot id: A0A8C9KTX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

9135:HARBI1
gene id: 9135:HARBI1
uniprot id: A0A8C9MHN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Cytoplasm
messages: Nucleus
messages: Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.

9135:PPIH
gene id: 9135:PPIH
uniprot id: A0A8C9NNG4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

9135:ADAM12
gene id: 9135:ADAM12
uniprot id: A0A8C9NG91
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:ATP5PD
gene id: 9135:ATP5PD
uniprot id: A0A8C9L185
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase d subunit family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion inner membrane

9135:ACO2
gene id: 9135:ACO2
uniprot id: A0A8C9MS70
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
messages: Mitochondrion

9135:VGLL4
gene id: 9135:VGLL4
uniprot id: A0A8C9N8W4
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

9135:PREPL
gene id: 9135:PREPL
uniprot id: A0A8C9N8W0
names: Similarity
messages: Belongs to the peptidase S9A family.

9135:FUT11
gene id: 9135:FUT11
uniprot id: A0A8C9L588
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane
messages: Probable fucosyltransferase.

9135:GPD1
gene id: 9135:GPD1
uniprot id: A0A8C9N178
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

9135:TMA16
gene id: 9135:TMA16
uniprot id: A0A8C9N8G1
names: Function
names: Similarity
names: Subunit
messages: Associates with pre-60S ribosomal particles.
messages: Belongs to the TMA16 family.
messages: Involved in the biogenesis of the 60S ribosomal subunit in the nucleus.

9135:EBF1
gene id: 9135:EBF1
uniprot id: A0A8C9NIA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

9135:ETV6
gene id: 9135:ETV6
uniprot id: A0A8C9MHK4
uniprot id: A0A8C9U2Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9135:CDR2
gene id: 9135:CDR2
uniprot id: A0A8C9NAT1
names: Similarity
messages: Belongs to the CDR2 family.

9135:ELOA
gene id: 9135:ELOA
uniprot id: A0A8C9MUB4
names: Subcellular Location Annotation
messages: Nucleus

9135:CALHM5
gene id: 9135:CALHM5
uniprot id: A0A8C9NNT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

9135:TCP11L1
gene id: 9135:TCP11L1
uniprot id: A0A8C9MX82
uniprot id: A0A8C9MZJ8
names: Similarity
messages: Belongs to the TCP11 family.

9135:KCNK1
gene id: 9135:KCNK1
uniprot id: A0A8C9MJQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: Recycling endosome
messages: Synaptic cell membrane
messages: Vesicle
messages: dendrite

9135:MAP2K1
gene id: 9135:MAP2K1
uniprot id: A0A8C9N4X5
names: Similarity
messages: Belongs to the protein kinase superfamily.

9135:FGG
gene id: 9135:FGG
uniprot id: A0A8C9NAY9
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

9135:LOC103820686
gene id: 9135:LOC103820686
uniprot id: A0A8C9UIE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

9135:LOC103813954
gene id: 9135:LOC103813954
uniprot id: A0A8C9NTL3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9135:LOC103827112
gene id: 9135:LOC103827112
uniprot id: A0A8C9N2S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX17 family.
messages: Mitochondrion intermembrane space

9135:RPL14
gene id: 9135:RPL14
uniprot id: A0A8C9KS53
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

9135:LOC103826452
gene id: 9135:LOC103826452
uniprot id: A0A8C9UBJ6
names: Similarity
messages: Belongs to the serpin family.

9135:LOC103820491
gene id: 9135:LOC103820491
uniprot id: A0A8C9MYN2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9135:LOC103820474
gene id: 9135:LOC103820474
uniprot id: A0A8C9MT90
names: Similarity
messages: Belongs to the aldo/keto reductase family.

9135:SRPX
gene id: 9135:SRPX
uniprot id: A0A8C9NA20
uniprot id: A0A8C9NE17
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:SLA
gene id: 9135:SLA
uniprot id: A0A8C9N1J2
names: Subcellular Location Annotation
messages: Cytoplasm

9135:LDHB
gene id: 9135:LDHB
uniprot id: A0A8C9N2W8
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

9135:SEPTIN7
gene id: 9135:SEPTIN7
uniprot id: A0A8C9UDE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Midbody
messages: cilium axoneme
messages: kinetochore
messages: spindle

9135:GPR146
gene id: 9135:GPR146
uniprot id: A0A8C9N523
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9135:UBE4B
gene id: 9135:UBE4B
uniprot id: A0A8C9NVV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

9135:GALNT11
gene id: 9135:GALNT11
uniprot id: A0A8C9MVD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9135:GIMD1
gene id: 9135:GIMD1
uniprot id: A0A8C9NJS5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

9135:PRORP
gene id: 9135:PRORP
uniprot id: A0A8C9N8Z7
names: Similarity
messages: Belongs to the PPR family. P subfamily.

9135:LOC103815769
gene id: 9135:LOC103815769
uniprot id: A0A8C9NBH9
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

9135:CDR2L
gene id: 9135:CDR2L
uniprot id: A0A8C9MDW0
names: Similarity
messages: Belongs to the CDR2 family.

9135:ERGIC2
gene id: 9135:ERGIC2
uniprot id: A0A8C9MPP8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

9135:AURKA
gene id: 9135:AURKA
uniprot id: A0A8C9NKT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
messages: centrosome

9135:COPS5
gene id: 9135:COPS5
uniprot id: A0A8C9UG13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M67A family. CSN5 subfamily.
messages: synaptic vesicle

9135:SAP18
gene id: 9135:SAP18
uniprot id: A0A8C9MQU8
names: Similarity
messages: Belongs to the SAP18 family.

9135:DOCK5
gene id: 9135:DOCK5
uniprot id: A0A8C9NV72
names: Similarity
messages: Belongs to the DOCK family.

9135:TBXAS1
gene id: 9135:TBXAS1
uniprot id: A0A8C9N726
names: Similarity
messages: Belongs to the cytochrome P450 family.

9135:PLAT
gene id: 9135:PLAT
uniprot id: A0A8C9NV07
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9135:FAH
gene id: 9135:FAH
uniprot id: A0A8C9MRN2
names: Similarity
messages: Belongs to the FAH family.

9135:FUT8
gene id: 9135:FUT8
uniprot id: A0A8C9MJ65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 23 family.
messages: Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.
messages: Golgi stack membrane
messages: Membrane

9135:LOC103812482
gene id: 9135:LOC103812482
uniprot id: A0A8C9NQV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

9135:ANXA6
gene id: 9135:ANXA6
uniprot id: A0A8C9NBG3
uniprot id: A0A8C9NDT5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: May associate with CD21. May regulate the release of Ca(2+) from intracellular stores.
messages: Melanosome

9135:LOC103825220
gene id: 9135:LOC103825220
uniprot id: A0A8C9N0W3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9135:SEMA4G
gene id: 9135:SEMA4G
uniprot id: A0A8C9UHX0
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:POMK
gene id: 9135:POMK
uniprot id: A0A8C9NHG3
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N-acetylglucosamine (GlcNAc)-beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-1,3-N-acetylglucosamine-beta-1,4-(phosphate-6-)mannose). Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Only shows kinase activity when the GalNAc-beta-3-GlcNAc-beta-terminus is linked to the 4-position of O-mannose, suggesting that this disaccharide serves as the substrate recognition motif.

9135:ALKBH1
gene id: 9135:ALKBH1
uniprot id: A0A8C9UCU0
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

9135:TMEM132A
gene id: 9135:TMEM132A
uniprot id: A0A8C9N636
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

9135:USP48
gene id: 9135:USP48
uniprot id: A0A8C9MJY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Nucleus

9135:MDM1
gene id: 9135:MDM1
uniprot id: A0A8C9MHA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM1 family.
messages: Nucleus
messages: centriole

9135:TM9SF4
gene id: 9135:TM9SF4
uniprot id: A0A8C9NKQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

9135:CLCF1
gene id: 9135:CLCF1
uniprot id: A0A8C9N297
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

9135:PCK1
gene id: 9135:PCK1
uniprot id: A0A8C9UHN0
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.

9135:ITGA6
gene id: 9135:ITGA6
uniprot id: A0A8C9NPV3
uniprot id: A0A8C9NTJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9135:APOA1
gene id: 9135:APOA1
uniprot id: A0A8C9U915
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

9135:ATP6V1E1
gene id: 9135:ATP6V1E1
uniprot id: A0A8C9MRT9
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

9135:CDH19
gene id: 9135:CDH19
uniprot id: A0A8C9MX36
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

9135:LDB1
gene id: 9135:LDB1
uniprot id: A0A8C9NVS2
names: Similarity
messages: Belongs to the LDB family.

9135:SH3YL1
gene id: 9135:SH3YL1
uniprot id: A0A8C9ND74
names: Similarity
messages: Belongs to the SH3YL1 family.

9135:LOC103819184
gene id: 9135:LOC103819184
uniprot id: A0A8C9MFY7
names: Similarity
messages: Belongs to the serpin family.

9135:PCNX4
gene id: 9135:PCNX4
uniprot id: A0A8C9MQE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

9135:GMPR
gene id: 9135:GMPR
uniprot id: A0A8C9KQK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

9135:LOC103814919
gene id: 9135:LOC103814919
uniprot id: A0A8C9UGT8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:CAPN10
gene id: 9135:CAPN10
uniprot id: A0A8C9NJA9
names: Similarity
messages: Belongs to the peptidase C2 family.

9135:CLK4
gene id: 9135:CLK4
uniprot id: A0A8C9UE71
names: Similarity
messages: Belongs to the protein kinase superfamily.

9135:EPHX1
gene id: 9135:EPHX1
uniprot id: A0A8C9NQC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

9135:ID2
gene id: 9135:ID2
uniprot id: A0A8C9NDW4
names: Subcellular Location Annotation
messages: Nucleus

9135:CES2
gene id: 9135:CES2
uniprot id: A0A8C9NAN4
uniprot id: A0A8C9NEE1
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

9135:LOC103813961
gene id: 9135:LOC103813961
uniprot id: A0A8C9NXX4
names: Similarity
messages: Belongs to the cytochrome P450 family.

9135:C11H16orf87
gene id: 9135:C11H16orf87
uniprot id: A0A8C9U7L8
names: Similarity
messages: Belongs to the UPF0547 family.

9135:MCMBP
gene id: 9135:MCMBP
uniprot id: A0A8C9NJ43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCMBP family.
messages: Nucleus

9135:FLI1
gene id: 9135:FLI1
uniprot id: A0A8C9NYA0
uniprot id: A0A8C9UIF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9135:SHOX
gene id: 9135:SHOX
uniprot id: A0A8C9NUX8
names: Subcellular Location Annotation
messages: Nucleus

9135:SEC61A2
gene id: 9135:SEC61A2
uniprot id: A0A8C9N6Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecY/SEC61-alpha family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9135:P2RY8
gene id: 9135:P2RY8
uniprot id: A0A8C9NVJ1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9135:LOC103822899
gene id: 9135:LOC103822899
uniprot id: A0A8C9U399
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

9135:P2RY4
gene id: 9135:P2RY4
uniprot id: A0A8C9L1R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9135:WT1
gene id: 9135:WT1
uniprot id: A0A8C9MYK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Cytoplasm
messages: Nucleus speckle

9135:SLC1A3
gene id: 9135:SLC1A3
uniprot id: A0A8C9MXZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

9135:MOCOS
gene id: 9135:MOCOS
uniprot id: A0A8C9U984
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.
messages: Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.

9135:FGF12
gene id: 9135:FGF12
uniprot id: A0A8C9NQN6
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9135:MRPS18C
gene id: 9135:MRPS18C
uniprot id: A0A8C9NPL2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS18 family.

9135:YEATS4
gene id: 9135:YEATS4
uniprot id: A0A8C9N546
names: Subcellular Location Annotation
messages: Nucleus

9135:FAM135A
gene id: 9135:FAM135A
uniprot id: A0A8C9N0V7
names: Similarity
messages: Belongs to the FAM135 family.

9135:SLC37A2
gene id: 9135:SLC37A2
uniprot id: A0A8C9NRG5
uniprot id: A0A8C9UIY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

9135:LOC103823829
gene id: 9135:LOC103823829
uniprot id: A0A8C9KUX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

9135:CPNE8
gene id: 9135:CPNE8
uniprot id: A0A8C9MPA4
names: Similarity
messages: Belongs to the copine family.

9135:BOLA3
gene id: 9135:BOLA3
uniprot id: A0A8C9MM57
names: Similarity
messages: Belongs to the BolA/IbaG family.

9135:RPL34
gene id: 9135:RPL34
uniprot id: A0A8C9NH26
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

9135:XPNPEP2
gene id: 9135:XPNPEP2
uniprot id: A0A8C9UI12
names: Similarity
messages: Belongs to the peptidase M24B family.

9135:MYO19
gene id: 9135:MYO19
uniprot id: A0A8C9N9E8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

9135:MRPL43
gene id: 9135:MRPL43
uniprot id: A0A8C9UIF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL43 family.
messages: Mitochondrion

9135:MRPS5
gene id: 9135:MRPS5
uniprot id: A0A8C9L2S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Nucleus

9135:FHL5
gene id: 9135:FHL5
uniprot id: A0A8C9L629
names: Function
names: Subcellular Location Annotation
messages: May be involved in the regulation of spermatogenesis. Stimulates CREM transcriptional activity in a phosphorylation-independent manner.
messages: Nucleus

9135:ARSI
gene id: 9135:ARSI
uniprot id: A0A8C9NCA0
names: Similarity
messages: Belongs to the sulfatase family.

9135:GART
gene id: 9135:GART
uniprot id: A0A8C9U754
names: Similarity
messages: In the C-terminal section; belongs to the GART family.
messages: In the N-terminal section; belongs to the GARS family.
messages: In the central section; belongs to the AIR synthase family.

9135:NPBWR2
gene id: 9135:NPBWR2
uniprot id: A0A8C9UH32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9135:TMEM150C
gene id: 9135:TMEM150C
uniprot id: A0A8C9NPW1
names: Subcellular Location Annotation
messages: Membrane

9135:CENPJ
gene id: 9135:CENPJ
uniprot id: A0A8C9U9D8
names: Similarity
messages: Belongs to the TCP10 family.

9135:B4GALT4
gene id: 9135:B4GALT4
uniprot id: A0A8C9N6P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

9135:SPCS1
gene id: 9135:SPCS1
uniprot id: A0A8C9KU24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9135:TPMT
gene id: 9135:TPMT
uniprot id: A0A8C9L5L6
uniprot id: A0A8C9MEZ5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.

9135:ODF2
gene id: 9135:ODF2
uniprot id: A0A8C9MU68
uniprot id: A0A8C9MU79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

9135:PTGES
gene id: 9135:PTGES
uniprot id: A0A8C9MPX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Membrane

9135:SLC5A1
gene id: 9135:SLC5A1
uniprot id: A0A8C9MK31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

9135:ZDHHC14
gene id: 9135:ZDHHC14
uniprot id: A0A8C9NKS7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9135:MYOZ1
gene id: 9135:MYOZ1
uniprot id: A0A8C9MFA4
names: Similarity
messages: Belongs to the myozenin family.

9135:GAL3ST1
gene id: 9135:GAL3ST1
uniprot id: A0A8C9KWI1
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

9135:ACSL5
gene id: 9135:ACSL5
uniprot id: A0A8C9NTJ0
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

9135:LOC103812328
gene id: 9135:LOC103812328
uniprot id: A0A8C9NVF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMP-30/CGR1 family.
messages: Cytoplasm

9135:CMKLR1
gene id: 9135:CMKLR1
uniprot id: A0A8C9MY01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

9135:CLDN14
gene id: 9135:CLDN14
uniprot id: A0A8C9N8R3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9135:RRM2B
gene id: 9135:RRM2B
uniprot id: A0A8C9MME8
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

9135:UBA5
gene id: 9135:UBA5
uniprot id: A0A8C9L4Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin-activating E1 family. UBA5 subfamily.
messages: Golgi apparatus

9135:VAMP3
gene id: 9135:VAMP3
uniprot id: A0A8C9MH00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

9135:HMBS
gene id: 9135:HMBS
uniprot id: A0A8C9NVC5
names: Similarity
messages: Belongs to the HMBS family.

9135:SLC46A3
gene id: 9135:SLC46A3
uniprot id: A0A8C9MTI9
names: Subcellular Location Annotation
messages: Membrane

9135:ODR4
gene id: 9135:ODR4
uniprot id: A0A8C9N529
names: Function
names: Similarity
messages: Belongs to the ODR-4 family.
messages: May play a role in the trafficking of a subset of G-protein coupled receptors.

9135:USP49
gene id: 9135:USP49
uniprot id: A0A8C9L1F6
names: Similarity
messages: Belongs to the peptidase C19 family.

9135:CNOT1
gene id: 9135:CNOT1
uniprot id: A0A8C9MRJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT1 family.
messages: Nucleus

9135:RBPJ
gene id: 9135:RBPJ
uniprot id: A0A8C9MN25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Su(H) family.
messages: Nucleus

9135:ORC1
gene id: 9135:ORC1
uniprot id: A0A8C9MS12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDC6/cdc18 family.
messages: Belongs to the ORC1 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Nucleus
messages: ORC is composed of six subunits.

9135:CALHM1
gene id: 9135:CALHM1
uniprot id: A0A8C9NVK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

9135:NRGN
gene id: 9135:NRGN
uniprot id: P54866
names: Function
names: Similarity
messages: Acts as a 'third messenger' substrate of protein kinase C-mediated molecular cascades during synaptic development and remodeling. Binds to calmodulin in the absence of calcium (By similarity).
messages: Belongs to the neurogranin family.

9135:MMP11
gene id: 9135:MMP11
uniprot id: A0A8C9MJA0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

9135:DOK5
gene id: 9135:DOK5
uniprot id: A0A8C9NND0
names: Similarity
messages: Belongs to the DOK family. Type B subfamily.

9135:GPR183
gene id: 9135:GPR183
uniprot id: A0A8C9UHI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9135:PRDM10
gene id: 9135:PRDM10
uniprot id: A0A8C9NWY3
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

9135:ZFPM2
gene id: 9135:ZFPM2
uniprot id: A0A8C9MTW3
names: Subcellular Location Annotation
messages: Nucleus

9135:EIF3D
gene id: 9135:EIF3D
uniprot id: A0A8C9MKS1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit D family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Cytoplasm
messages: The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.

9135:MED30
gene id: 9135:MED30
uniprot id: A0A8C9MWI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 30 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

9135:ABCC10
gene id: 9135:ABCC10
uniprot id: A0A8C9NDR2
names: Subcellular Location Annotation
messages: Membrane

9135:CEBPG
gene id: 9135:CEBPG
uniprot id: A0A8C9NDY2
names: Similarity
messages: Belongs to the bZIP family. C/EBP subfamily.

9135:LOC103813624
gene id: 9135:LOC103813624
uniprot id: A0A8C9MSW7
names: Similarity
messages: Belongs to the heat shock protein 70 family.

9135:SMC6
gene id: 9135:SMC6
uniprot id: A0A8C9NE45
names: Subcellular Location Annotation
messages: Chromosome

9135:TADA3
gene id: 9135:TADA3
uniprot id: A0A8C9MR57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGG1 family.
messages: Nucleus

9135:COPB2
gene id: 9135:COPB2
uniprot id: A0A8C9UIM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat COPB2 family.
messages: COPI-coated vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
messages: This coatomer complex protein, essential for Golgi budding and vesicular trafficking, is a selective binding protein (RACK) for protein kinase C, epsilon type. It binds to Golgi membranes in a GTP-dependent manner.

9135:AASDHPPT
gene id: 9135:AASDHPPT
uniprot id: A0A8C9MLS1
names: Similarity
messages: Belongs to the P-Pant transferase superfamily. AcpS family.

9135:KAT6A
gene id: 9135:KAT6A
uniprot id: A0A8C9NVB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

9135:LOC103816733
gene id: 9135:LOC103816733
uniprot id: A0A8C9MW00
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

9135:MAFK
gene id: 9135:MAFK
uniprot id: A0A8C9N5A8
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

9135:POPDC3
gene id: 9135:POPDC3
uniprot id: A0A8C9MEZ8
names: Similarity
messages: Belongs to the popeye family.

9135:LAMP3
gene id: 9135:LAMP3
uniprot id: A0A8C9NE33
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lysosome membrane
messages: Membrane

9135:JPT2
gene id: 9135:JPT2
uniprot id: A0A8C9MGW3
uniprot id: A0A8C9MGZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

9135:CDC25A
gene id: 9135:CDC25A
uniprot id: A0A8C9MQP1
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

9135:EXOC3L4
gene id: 9135:EXOC3L4
uniprot id: A0A8C9MUQ8
uniprot id: A0A8C9MV70
names: Similarity
messages: Belongs to the SEC6 family.

9135:SPSB1
gene id: 9135:SPSB1
uniprot id: A0A8C9NW90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

9135:DHX30
gene id: 9135:DHX30
uniprot id: A0A8C9MR78
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily.

9135:CDK14
gene id: 9135:CDK14
uniprot id: A0A8C9NBZ0
names: Similarity
messages: Belongs to the protein kinase superfamily.

9135:LOC103826888
gene id: 9135:LOC103826888
uniprot id: A0A8C9MYA9
names: Similarity
messages: Belongs to the serpin family.

9135:TMEM45B
gene id: 9135:TMEM45B
uniprot id: A0A8C9NU52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

9135:CRYBG1
gene id: 9135:CRYBG1
uniprot id: A0A8C9KU75
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

9135:GHRHR
gene id: 9135:GHRHR
uniprot id: A0A8C9UBA6
names: Subcellular Location Annotation
messages: Membrane

9135:TAGLN3
gene id: 9135:TAGLN3
uniprot id: A0A8C9NQJ4
names: Similarity
messages: Belongs to the calponin family.

9135:PHYKPL
gene id: 9135:PHYKPL
uniprot id: A0A8C9N8G9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

9135:ARL6
gene id: 9135:ARL6
uniprot id: A0A8C9NEV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: cilium membrane

9135:LOC103822691
gene id: 9135:LOC103822691
uniprot id: A0A8C9NUR4
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

9135:FAM174C
gene id: 9135:FAM174C
uniprot id: A0A8C9MUM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM174 family.
messages: Membrane

9135:ELF3
gene id: 9135:ELF3
uniprot id: A0A8C9UB60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9135:SKA3
gene id: 9135:SKA3
uniprot id: A0A8C9MRE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKA3 family.
messages: kinetochore
messages: spindle

9135:LOC103813347
gene id: 9135:LOC103813347
uniprot id: A0A8C9MUQ2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9135:LOC103817985
gene id: 9135:LOC103817985
uniprot id: A0A8C9KYH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCR10/QCR9 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

9135:OTOP2
gene id: 9135:OTOP2
uniprot id: A0A8C9L2X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

9135:TMPRSS13
gene id: 9135:TMPRSS13
uniprot id: A0A8C9UA71
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:RAB4A
gene id: 9135:RAB4A
uniprot id: A0A8C9MJM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport.

9135:NFRKB
gene id: 9135:NFRKB
uniprot id: A0A8C9NU42
names: Subcellular Location Annotation
messages: Nucleus

9135:TAF1
gene id: 9135:TAF1
uniprot id: A0A8C9NQI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF1 family.
messages: Nucleus

9135:RCAN1
gene id: 9135:RCAN1
uniprot id: A0A8C9N7J0
uniprot id: A0A8C9N9N3
names: Similarity
messages: Belongs to the RCAN family.

9135:TCP1
gene id: 9135:TCP1
uniprot id: A0A8C9NBL7
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

9135:CRYBA2
gene id: 9135:CRYBA2
uniprot id: A0A8C9NJ46
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

9135:INPP5B
gene id: 9135:INPP5B
uniprot id: A0A8C9NRK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: phagosome membrane

9135:GPSM1
gene id: 9135:GPSM1
uniprot id: A0A8C9MGE2
uniprot id: A0A8C9U3M7
names: Similarity
messages: Belongs to the GPSM family.

9135:PRPF19
gene id: 9135:PRPF19
uniprot id: A0A8C9N4Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PRP19 family.
messages: Homotetramer.
messages: Lipid droplet
messages: Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.
messages: nucleoplasm

9135:NDUFA1
gene id: 9135:NDUFA1
uniprot id: A0A8C9NX41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA1 subunit family.
messages: Mitochondrion inner membrane

9135:NTF3
gene id: 9135:NTF3
uniprot id: A0A8C9UC43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Secreted
messages: Seems to promote the survival of visceral and proprioceptive sensory neurons.

9135:LOC103824340
gene id: 9135:LOC103824340
uniprot id: A0A8C9L3H9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

9135:CYP2J19
gene id: 9135:CYP2J19
uniprot id: A0A8C9MW13
names: Similarity
messages: Belongs to the cytochrome P450 family.

9135:PRKAB2
gene id: 9135:PRKAB2
uniprot id: A0A8C9NPU0
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

9135:NUDT1
gene id: 9135:NUDT1
uniprot id: A0A8C9N3E9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Monomer.
messages: Nucleus

9135:EEF2K
gene id: 9135:EEF2K
uniprot id: A0A8C9N857
uniprot id: A0A8C9N9H9
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. Alpha-type protein kinase family.
messages: Monomer or homodimer.
messages: Undergoes calcium/calmodulin-dependent intramolecular autophosphorylation, and this results in it becoming partially calcium/calmodulin-independent.

9135:FOXB1
gene id: 9135:FOXB1
uniprot id: A0A8C9UHV2
names: Subcellular Location Annotation
messages: Nucleus

9135:PTGFR
gene id: 9135:PTGFR
uniprot id: A0A8C9NM16
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9135:HYAL1
gene id: 9135:HYAL1
uniprot id: A0A8C9KXR4
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

9135:GJC1
gene id: 9135:GJC1
uniprot id: A0A8C9N1T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Gamma-type subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9135:RPLP1
gene id: 9135:RPLP1
uniprot id: A0A8C9N409
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

9135:EIF3E
gene id: 9135:EIF3E
uniprot id: A0A8C9MUL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit E family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm
messages: Nucleus

9135:RRH
gene id: 9135:RRH
uniprot id: A0A8C9NHP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

9135:NMBR
gene id: 9135:NMBR
uniprot id: A0A8C9UGG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9135:IL2RB
gene id: 9135:IL2RB
uniprot id: A0A8C9MLD5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Cell membrane
messages: Membrane
messages: Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit. Interacts with SHB upon interleukin stimulation.

9135:LOC103820700
gene id: 9135:LOC103820700
uniprot id: A0A8C9NTN9
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

9135:GJA1
gene id: 9135:GJA1
uniprot id: A0A8C9UGE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9135:UGP2
gene id: 9135:UGP2
uniprot id: A0A8C9KUI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDPGP type 1 family.
messages: Homooctamer.
messages: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.

9135:EIF1B
gene id: 9135:EIF1B
uniprot id: A0A8C9KTZ8
names: Similarity
messages: Belongs to the SUI1 family.

9135:UROC1
gene id: 9135:UROC1
uniprot id: A0A8C9MPZ3
names: Similarity
messages: Belongs to the urocanase family.

9135:ACTA2
gene id: 9135:ACTA2
uniprot id: A0A8C9NY38
names: Similarity
messages: Belongs to the actin family.

9135:TMCO1
gene id: 9135:TMCO1
uniprot id: A0A8C9MER7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMCO1 family.
messages: Calcium-selective channel required to prevent calcium stores from overfilling.
messages: Endoplasmic reticulum membrane
messages: Membrane

9135:KDM1B
gene id: 9135:KDM1B
uniprot id: A0A8C9L2J8
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

9135:CLDN11
gene id: 9135:CLDN11
uniprot id: A0A8C9N859
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9135:XPR1
gene id: 9135:XPR1
uniprot id: A0A8C9L2V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYG1 (TC 2.A.94) family.
messages: Membrane

9135:LOC103826028
gene id: 9135:LOC103826028
uniprot id: A0A8C9NJY7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9135:ACTA1
gene id: 9135:ACTA1
uniprot id: A0A8C9MJH4
names: Similarity
messages: Belongs to the actin family.

9135:HOXA11
gene id: 9135:HOXA11
uniprot id: A0A8C9NRA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

9135:OXCT1
gene id: 9135:OXCT1
uniprot id: A0A8C9N2M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
messages: Mitochondrion

9135:MMP23B
gene id: 9135:MMP23B
uniprot id: A0A8C9NYB8
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:HDC
gene id: 9135:HDC
uniprot id: A0A8C9MQR1
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

9135:GALR3
gene id: 9135:GALR3
uniprot id: A0A8C9U6A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

9135:VEGFD
gene id: 9135:VEGFD
uniprot id: A0A8C9NK74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Secreted

9135:HEATR1
gene id: 9135:HEATR1
uniprot id: A0A8C9MM08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HEATR1/UTP10 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

9135:CX3CR1
gene id: 9135:CX3CR1
uniprot id: A0A8C9KZV4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9135:C8B
gene id: 9135:C8B
uniprot id: A0A8C9UA79
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9135:OTULINL
gene id: 9135:OTULINL
uniprot id: A0A8C9MLB4
uniprot id: A0A8C9MM20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C65 family. Otulin subfamily.
messages: Cytoplasm

9135:FAM83C
gene id: 9135:FAM83C
uniprot id: A0A8C9N7K1
names: Similarity
messages: Belongs to the FAM83 family.

9135:NT5C2
gene id: 9135:NT5C2
uniprot id: A0A8C9NSQ8
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

9135:PDE7B
gene id: 9135:PDE7B
uniprot id: A0A8C9MH57
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9135:MAN1C1
gene id: 9135:MAN1C1
uniprot id: A0A8C9MWF1
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

9135:NDRG3
gene id: 9135:NDRG3
uniprot id: A0A8C9NAD3
uniprot id: A0A8C9NDK5
names: Similarity
messages: Belongs to the NDRG family.

9135:LOC103825943
gene id: 9135:LOC103825943
uniprot id: A0A8C9MSM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

9135:MYH9
gene id: 9135:MYH9
uniprot id: A0A8C9MLK7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

9135:ALX4
gene id: 9135:ALX4
uniprot id: A0A8C9MJ39
names: Subcellular Location Annotation
messages: Nucleus

9135:VTI1B
gene id: 9135:VTI1B
uniprot id: A0A8C9UG22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

9135:COPG1
gene id: 9135:COPG1
uniprot id: A0A8C9MNH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

9135:POSTN
gene id: 9135:POSTN
uniprot id: A0A8C9NC68
uniprot id: A0A8C9NDX9
uniprot id: A0A8C9NFH9
uniprot id: A0A8C9NHX9
names: Subcellular Location Annotation
messages: extracellular matrix

9135:GRHL3
gene id: 9135:GRHL3
uniprot id: A0A8C9MVS5
names: Subcellular Location Annotation
messages: Nucleus

9135:TADA2B
gene id: 9135:TADA2B
uniprot id: A0A8C9UI30
names: Subcellular Location Annotation
messages: Nucleus

9135:NXPH1
gene id: 9135:NXPH1
uniprot id: A0A8C9NGH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

9135:LOC103820036
gene id: 9135:LOC103820036
uniprot id: A0A8C9MKP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

9135:RRAGD
gene id: 9135:RRAGD
uniprot id: A0A8C9U2S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

9135:ADCK1
gene id: 9135:ADCK1
uniprot id: A0A8C9N380
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.
messages: Secreted

9135:SOSTDC1
gene id: 9135:SOSTDC1
uniprot id: A0A8C9NK67
names: Caution
names: Similarity
messages: Belongs to the sclerostin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:ST6GALNAC2
gene id: 9135:ST6GALNAC2
uniprot id: A0A8C9MIB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9135:LOC103812565
gene id: 9135:LOC103812565
uniprot id: A0A8C9NEX9
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

9135:NDUFB5
gene id: 9135:NDUFB5
uniprot id: A0A8C9UF13
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB5 subunit family.
messages: Complex I is composed of 45 different subunits.

9135:MDM4
gene id: 9135:MDM4
uniprot id: A0A8C9MWQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain.
messages: Nucleus

9135:VEGFC
gene id: 9135:VEGFC
uniprot id: A0A8C9UDH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Secreted

9135:AP3M2
gene id: 9135:AP3M2
uniprot id: A0A8C9NV98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus

9135:LRRC8B
gene id: 9135:LRRC8B
uniprot id: A0A8C9NK44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

9135:EIF2B1
gene id: 9135:EIF2B1
uniprot id: A0A8C9N2Y5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.
messages: Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
messages: Complex of five different subunits; alpha, beta, gamma, delta and epsilon.

9135:SLC25A19
gene id: 9135:SLC25A19
uniprot id: A0A8C9KR30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9135:SLC37A4
gene id: 9135:SLC37A4
uniprot id: A0A8C9NTN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

9135:MTX2
gene id: 9135:MTX2
uniprot id: A0A8C9NU40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

9135:CBR1
gene id: 9135:CBR1
uniprot id: A0A8C9NAF2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9135:CLCC1
gene id: 9135:CLCC1
uniprot id: A0A8C9NB16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel MCLC family.
messages: Membrane

9135:INO80D
gene id: 9135:INO80D
uniprot id: A0A8C9MFH8
names: Subcellular Location Annotation
messages: Nucleus

9135:SLC46A1
gene id: 9135:SLC46A1
uniprot id: A0A8C9MVE9
names: Subcellular Location Annotation
messages: Membrane

9135:ACTC1
gene id: 9135:ACTC1
uniprot id: A0A8C9NDN5
names: Similarity
messages: Belongs to the actin family.

9135:LOC103816736
gene id: 9135:LOC103816736
uniprot id: A0A8C9MUU9
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

9135:TEX10
gene id: 9135:TEX10
uniprot id: A0A8C9MVC2
names: Similarity
messages: Belongs to the IPI1/TEX10 family.

9135:MBOAT1
gene id: 9135:MBOAT1
uniprot id: A0A8C9KVD0
names: Subcellular Location Annotation
messages: Membrane

9135:SNW1
gene id: 9135:SNW1
uniprot id: A0A8C9N1D4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNW family.
messages: Identified in the spliceosome C complex.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

9135:SLC18A2
gene id: 9135:SLC18A2
uniprot id: A0A8C9NK72
names: Subcellular Location Annotation
messages: Membrane

9135:IL17REL
gene id: 9135:IL17REL
uniprot id: A0A8C9MKP2
names: Subcellular Location Annotation
messages: Cell membrane

9135:CRAT
gene id: 9135:CRAT
uniprot id: A0A8C9MPW2
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

9135:KCNQ5
gene id: 9135:KCNQ5
uniprot id: A0A8C9MYN7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9135:ELK3
gene id: 9135:ELK3
uniprot id: A0A8C9MVH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9135:LOC103817657
gene id: 9135:LOC103817657
uniprot id: A0A8C9N4E1
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

9135:UNC5A
gene id: 9135:UNC5A
uniprot id: A0A8C9NI85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

9135:NECAP1
gene id: 9135:NECAP1
uniprot id: A0A8C9NQG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

9135:STARD8
gene id: 9135:STARD8
uniprot id: A0A8C9KQI0
uniprot id: A0A8C9KWN6
uniprot id: A0A8C9MEX9
names: Subcellular Location Annotation
messages: Cytoplasm

9135:DPYS
gene id: 9135:DPYS
uniprot id: A0A8C9MTA7
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

9135:PRKCI
gene id: 9135:PRKCI
uniprot id: A0A8C9N4A2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

9135:LOC103817463
gene id: 9135:LOC103817463
uniprot id: A0A8C9N7M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

9135:GTF2E1
gene id: 9135:GTF2E1
uniprot id: A0A8C9N605
names: Function
names: Similarity
messages: Belongs to the TFIIE alpha subunit family.
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.

9135:EIF4A3
gene id: 9135:EIF4A3
uniprot id: A0A8C9KTD9
names: Similarity
messages: Belongs to the DEAD box helicase family.

9135:LOC103819810
gene id: 9135:LOC103819810
uniprot id: A0A8C9NKK8
names: Similarity
messages: Belongs to the NDK family.

9135:MFN2
gene id: 9135:MFN2
uniprot id: A0A8C9MHQ0
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

9135:TMEM53
gene id: 9135:TMEM53
uniprot id: A0A8C9L1U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM53 family.
messages: Membrane
messages: Nucleus outer membrane

9135:UROS
gene id: 9135:UROS
uniprot id: A0A8C9NJG7
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.

9135:TFB1M
gene id: 9135:TFB1M
uniprot id: A0A8C9NJG9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

9135:RABGGTB
gene id: 9135:RABGGTB
uniprot id: A0A8C9N1T8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.

9135:DOLK
gene id: 9135:DOLK
uniprot id: A0A8C9U7V4
names: Similarity
messages: Belongs to the polyprenol kinase family.

9135:LUC7L3
gene id: 9135:LUC7L3
uniprot id: A0A8C9NNK0
names: Similarity
messages: Belongs to the Luc7 family.

9135:TPM4
gene id: 9135:TPM4
uniprot id: A0A8C9NM87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

9135:AIG1
gene id: 9135:AIG1
uniprot id: A0A8C9NN93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIG1 family.
messages: Membrane

9135:TEF
gene id: 9135:TEF
uniprot id: A0A8C9MR01
uniprot id: A0A8C9MRK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

9135:SFRP1
gene id: 9135:SFRP1
uniprot id: A0A8C9NT33
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9135:DDX3X
gene id: 9135:DDX3X
uniprot id: A0A8C9NDR5
names: Similarity
messages: Belongs to the DEAD box helicase family.

9135:TM4SF18
gene id: 9135:TM4SF18
uniprot id: A0A8C9N243
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

9135:CRYL1
gene id: 9135:CRYL1
uniprot id: A0A8C9MPD6
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

9135:ATP5F1C
gene id: 9135:ATP5F1C
uniprot id: A0A8C9N7A5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

9135:MRPS25
gene id: 9135:MRPS25
uniprot id: A0A8C9NQT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS25 family.
messages: Mitochondrion

9135:MRPL32
gene id: 9135:MRPL32
uniprot id: A0A8C9NQ76
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

9135:AP2A2
gene id: 9135:AP2A2
uniprot id: A0A8C9U672
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit AP2A1 or AP2A2 and beta-type subunit AP2B1), a medium adaptin (mu-type subunit AP2M1) and a small adaptin (sigma-type subunit AP2S1).
messages: Belongs to the adaptor complexes large subunit family.
messages: Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules. AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway. The AP-2 alpha subunit binds polyphosphoinositide-containing lipids, positioning AP-2 on the membrane. The AP-2 alpha subunit acts via its C-terminal appendage domain as a scaffolding platform for endocytic accessory proteins. The AP-2 alpha and AP-2 sigma subunits are thought to contribute to the recognition of the [ED]-X-X-X-L-[LI] motif.
messages: coated pit

9135:HOXD10
gene id: 9135:HOXD10
uniprot id: A0A8C9NQB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

9135:UBP1
gene id: 9135:UBP1
uniprot id: A0A8C9NLD7
uniprot id: A0A8C9NR22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

9135:APOH
gene id: 9135:APOH
uniprot id: A0A8C9NHM9
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9135:NOX1
gene id: 9135:NOX1
uniprot id: A0A8C9MJD1
names: Subcellular Location Annotation
messages: Membrane

9135:ACYP1
gene id: 9135:ACYP1
uniprot id: A0A8C9N329
names: Similarity
messages: Belongs to the acylphosphatase family.

9135:YTHDF3
gene id: 9135:YTHDF3
uniprot id: A0A8C9UGN4
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

9135:LOC103818022
gene id: 9135:LOC103818022
uniprot id: A0A8C9MJU2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferrin family.
messages: Monomer.
messages: Secreted

9135:ANAPC10
gene id: 9135:ANAPC10
uniprot id: A0A8C9UHC9
names: Function
names: Similarity
messages: Belongs to the APC10 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.

9135:NDUFA2
gene id: 9135:NDUFA2
uniprot id: A0A8C9UDE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA2 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9135:CDC42EP3
gene id: 9135:CDC42EP3
uniprot id: A0A8C9UF46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

9135:OXTR
gene id: 9135:OXTR
uniprot id: A0A8C9NR82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

9135:UNC93A
gene id: 9135:UNC93A
uniprot id: A0A8C9U3T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

9135:LOC103823243
gene id: 9135:LOC103823243
uniprot id: A0A8C9NMP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

9135:NOL10
gene id: 9135:NOL10
uniprot id: A0A8C9NET4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat NOL10/ENP2 family.
messages: nucleolus

9135:LOC103826450
gene id: 9135:LOC103826450
uniprot id: A0A8C9MXN2
names: Similarity
messages: Belongs to the serpin family.

9135:APTX
gene id: 9135:APTX
uniprot id: A0A8C9NA18
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus
messages: nucleoplasm

9135:CAB39L
gene id: 9135:CAB39L
uniprot id: A0A8C9NJQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

9135:RIC8A
gene id: 9135:RIC8A
uniprot id: A0A8C9N1K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synembryn family.
messages: Cytoplasm
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
messages: Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.

9135:SEC61A1
gene id: 9135:SEC61A1
uniprot id: A0A8C9MNS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecY/SEC61-alpha family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9135:SDAD1
gene id: 9135:SDAD1
uniprot id: A0A8C9MLV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDA1 family.
messages: Required for 60S pre-ribosomal subunits export to the cytoplasm.
messages: nucleolus

9135:FGA
gene id: 9135:FGA
uniprot id: A0A8C9NDK4
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

9135:CTNS
gene id: 9135:CTNS
uniprot id: A0A8C9UDM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cystinosin family.
messages: Membrane

9135:DYNLRB1
gene id: 9135:DYNLRB1
uniprot id: A0A8C9N0P9
names: Similarity
messages: Belongs to the GAMAD family.

9135:ENTPD2
gene id: 9135:ENTPD2
uniprot id: A0A8C9NCL3
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

9135:ITGB3
gene id: 9135:ITGB3
uniprot id: A0A8C9N8P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

9135:RPS6KA5
gene id: 9135:RPS6KA5
uniprot id: A0A8C9N0U8
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

9135:EPYC
gene id: 9135:EPYC
uniprot id: A0A8C9UC65
names: Similarity
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.

9135:ATP5F1A
gene id: 9135:ATP5F1A
uniprot id: A0A8C9NV97
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

9135:HMGCL
gene id: 9135:HMGCL
uniprot id: A0A8C9MW72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HMG-CoA lyase family.
messages: Homodimer; disulfide-linked. Can also form homotetramers.
messages: Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.

9135:TIMM21
gene id: 9135:TIMM21
uniprot id: A0A8C9MXW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM21 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane

9135:PUS7L
gene id: 9135:PUS7L
uniprot id: A0A8C9NIF0
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

9135:TRPM2
gene id: 9135:TRPM2
uniprot id: A0A8C9N0G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. TRPM2 sub-subfamily.
messages: Cell membrane
messages: Membrane

9135:HYOU1
gene id: 9135:HYOU1
uniprot id: A0A8C9NYE7
names: Similarity
messages: Belongs to the heat shock protein 70 family.

9135:LOC103817855
gene id: 9135:LOC103817855
uniprot id: A0A8C9N4B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

9135:FUT7
gene id: 9135:FUT7
uniprot id: A0A8C9N7K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

9135:ATP2C2
gene id: 9135:ATP2C2
uniprot id: A0A8C9MTX9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9135:PSMD2
gene id: 9135:PSMD2
uniprot id: A0A8C9NKE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S2 family.
messages: Binds to the intracellular domain of tumor necrosis factor type 1 receptor. The binding domain of TRAP1 and TRAP2 resides outside the death domain of TNFR1.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

9135:FECH
gene id: 9135:FECH
uniprot id: A0A8C9MJT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Mitochondrion inner membrane

9135:EMP1
gene id: 9135:EMP1
uniprot id: A0A8C9MUZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

9135:LOC103823672
gene id: 9135:LOC103823672
uniprot id: A0A8C9NQ21
names: Similarity
messages: Belongs to the SLBP family.

9135:BDKRB1
gene id: 9135:BDKRB1
uniprot id: A0A8C9MXD0
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation.

9135:GNL2
gene id: 9135:GNL2
uniprot id: A0A8C9UHI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
messages: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.
messages: nucleolus