90244:I6G29 RS09510
gene id: 90244:I6G29_RS09510
uniprot id: A0A378XGM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

90244:I6G29 RS07570
gene id: 90244:I6G29_RS07570
uniprot id: A0A378XHC7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

90244:I6G29 RS04755
gene id: 90244:I6G29_RS04755
uniprot id: A0A378XGA1
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS09645
gene id: 90244:I6G29_RS09645
uniprot id: A0A378XG78
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

90244:I6G29 RS09805
gene id: 90244:I6G29_RS09805
uniprot id: A0A378XGU2
names: Subcellular Location Annotation
messages: Cytoplasm

90244:I6G29 RS06915
gene id: 90244:I6G29_RS06915
uniprot id: A0A378XGY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

90244:I6G29 RS02485
gene id: 90244:I6G29_RS02485
uniprot id: A0A378XDA9
names: Similarity
messages: Belongs to the thioredoxin family.

90244:I6G29 RS09735
gene id: 90244:I6G29_RS09735
uniprot id: A0A378XIK3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the multicopper oxidase family.
messages: Binds 1 Cu(+) ion.
messages: Homotrimer.
messages: Periplasm

90244:I6G29 RS02490
gene id: 90244:I6G29_RS02490
uniprot id: A0A378XEA9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS11075
gene id: 90244:I6G29_RS11075
uniprot id: A0A378XJ98
names: Function
names: Subcellular Location Annotation
messages: Periplasm
messages: Transfers electrons from cytochrome c551 to cytochrome oxidase.

90244:I6G29 RS10875
gene id: 90244:I6G29_RS10875
uniprot id: A0A378XJ61
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

90244:I6G29 RS05170
gene id: 90244:I6G29_RS05170
uniprot id: A0A378XFZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

90244:I6G29 RS09690
gene id: 90244:I6G29_RS09690
uniprot id: A0A378XIJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

90244:I6G29 RS06770
gene id: 90244:I6G29_RS06770
uniprot id: A0A378XHD8
names: Similarity
messages: Belongs to the universal stress protein A family.

90244:I6G29 RS10650
gene id: 90244:I6G29_RS10650
uniprot id: A0A378XH58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

90244:I6G29 RS12795
gene id: 90244:I6G29_RS12795
uniprot id: A0A378XJG1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

90244:I6G29 RS00735
gene id: 90244:I6G29_RS00735
uniprot id: A0A378XA95
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

90244:I6G29 RS00990
gene id: 90244:I6G29_RS00990
uniprot id: A0A378XAM2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

90244:I6G29 RS10215
gene id: 90244:I6G29_RS10215
uniprot id: A0A378XIU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

90244:I6G29 RS01095
gene id: 90244:I6G29_RS01095
uniprot id: A0A378XBK3
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

90244:I6G29 RS08165
gene id: 90244:I6G29_RS08165
uniprot id: A0A378XI65
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS01495
gene id: 90244:I6G29_RS01495
uniprot id: A0A378XDQ3
names: Similarity
messages: Belongs to the asparagine synthetase family.

90244:I6G29 RS11255
gene id: 90244:I6G29_RS11255
uniprot id: A0A378XHH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

90244:I6G29 RS12740
gene id: 90244:I6G29_RS12740
uniprot id: A0A378XHY7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

90244:I6G29 RS08910
gene id: 90244:I6G29_RS08910
uniprot id: A0A378XG94
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS11025
gene id: 90244:I6G29_RS11025
uniprot id: A0A378XJ84
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

90244:I6G29 RS11955
gene id: 90244:I6G29_RS11955
uniprot id: A0A378XJT6
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

90244:I6G29 RS05675
gene id: 90244:I6G29_RS05675
uniprot id: A0A378XFG0
names: Similarity
messages: Belongs to the UPF0102 family.

90244:I6G29 RS02840
gene id: 90244:I6G29_RS02840
uniprot id: A0A378XCD7
names: Similarity
messages: Belongs to the Lgt family.

90244:I6G29 RS07435
gene id: 90244:I6G29_RS07435
uniprot id: A0A378XH62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

90244:I6G29 RS00945
gene id: 90244:I6G29_RS00945
uniprot id: A0A378XAH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

90244:I6G29 RS03465
gene id: 90244:I6G29_RS03465
uniprot id: A0A378XF56
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS07265
gene id: 90244:I6G29_RS07265
uniprot id: A0A378XG69
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

90244:I6G29 RS00740
gene id: 90244:I6G29_RS00740
uniprot id: A0A378X9P2
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

90244:I6G29 RS01910
gene id: 90244:I6G29_RS01910
uniprot id: A0A378XBR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

90244:I6G29 RS07250
gene id: 90244:I6G29_RS07250
uniprot id: A0A378XF85
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

90244:I6G29 RS00835
gene id: 90244:I6G29_RS00835
uniprot id: A0A378XC78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

90244:I6G29 RS09600
gene id: 90244:I6G29_RS09600
uniprot id: A0A378XHR1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

90244:I6G29 RS00820
gene id: 90244:I6G29_RS00820
uniprot id: A0A378XCF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

90244:I6G29 RS03435
gene id: 90244:I6G29_RS03435
uniprot id: A0A378XEZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

90244:I6G29 RS13565
gene id: 90244:I6G29_RS13565
uniprot id: A0A378X9M1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

90244:I6G29 RS06695
gene id: 90244:I6G29_RS06695
uniprot id: A0A378XF04
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

90244:I6G29 RS04210
gene id: 90244:I6G29_RS04210
uniprot id: A0A378XD75
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

90244:I6G29 RS00415
gene id: 90244:I6G29_RS00415
uniprot id: A0A378XCF0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

90244:I6G29 RS11110
gene id: 90244:I6G29_RS11110
uniprot id: A0A378XJB6
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

90244:I6G29 RS03975
gene id: 90244:I6G29_RS03975
uniprot id: A0A378XEA8
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

90244:I6G29 RS10660
gene id: 90244:I6G29_RS10660
uniprot id: A0A378XJ23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

90244:I6G29 RS13180
gene id: 90244:I6G29_RS13180
uniprot id: A0A378XHY1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

90244:I6G29 RS11070
gene id: 90244:I6G29_RS11070
uniprot id: A0A378XJV7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

90244:I6G29 RS01670
gene id: 90244:I6G29_RS01670
uniprot id: A0A378XAU7
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

90244:I6G29 RS00540
gene id: 90244:I6G29_RS00540
uniprot id: A0A378XBY5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

90244:I6G29 RS10920
gene id: 90244:I6G29_RS10920
uniprot id: A0A378XJS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

90244:I6G29 RS07790
gene id: 90244:I6G29_RS07790
uniprot id: A0A378XHF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

90244:I6G29 RS02895
gene id: 90244:I6G29_RS02895
uniprot id: A0A378XDV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

90244:I6G29 RS03095
gene id: 90244:I6G29_RS03095
uniprot id: A0A378XC88
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

90244:I6G29 RS11560
gene id: 90244:I6G29_RS11560
uniprot id: A0A378XIL9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

90244:I6G29 RS06210
gene id: 90244:I6G29_RS06210
uniprot id: A0A378XEM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

90244:I6G29 RS06350
gene id: 90244:I6G29_RS06350
uniprot id: A0A378XBF4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

90244:I6G29 RS09605
gene id: 90244:I6G29_RS09605
uniprot id: A0A378XGP8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

90244:I6G29 RS07975
gene id: 90244:I6G29_RS07975
uniprot id: A0A378XHL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

90244:I6G29 RS06610
gene id: 90244:I6G29_RS06610
uniprot id: A0A378XEY7
names: Cofactor
names: Function
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.

90244:I6G29 RS00660
gene id: 90244:I6G29_RS00660
uniprot id: A0A378XC35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

90244:I6G29 RS06850
gene id: 90244:I6G29_RS06850
uniprot id: A0A378XED0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

90244:I6G29 RS12575
gene id: 90244:I6G29_RS12575
uniprot id: A0A378XKS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

90244:I6G29 RS13385
gene id: 90244:I6G29_RS13385
uniprot id: A0A378X8S7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

90244:I6G29 RS01980
gene id: 90244:I6G29_RS01980
uniprot id: A0A378XBV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

90244:I6G29 RS06990
gene id: 90244:I6G29_RS06990
uniprot id: A0A378XF37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

90244:I6G29 RS11815
gene id: 90244:I6G29_RS11815
uniprot id: A0A378XJQ5
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

90244:I6G29 RS11745
gene id: 90244:I6G29_RS11745
uniprot id: A0A378XHW0
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS08540
gene id: 90244:I6G29_RS08540
uniprot id: A0A378XHR2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

90244:I6G29 RS09835
gene id: 90244:I6G29_RS09835
uniprot id: A0A378XJ67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

90244:I6G29 RS02800
gene id: 90244:I6G29_RS02800
uniprot id: A0A378XC31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MerT family.
messages: Cell inner membrane
messages: Membrane

90244:I6G29 RS08635
gene id: 90244:I6G29_RS08635
uniprot id: A0A378XHX0
names: Similarity
messages: Belongs to the asparaginase 1 family.

90244:I6G29 RS09745
gene id: 90244:I6G29_RS09745
uniprot id: A0A378XG97
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

90244:I6G29 RS09350
gene id: 90244:I6G29_RS09350
uniprot id: A0A378XG12
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

90244:I6G29 RS03575
gene id: 90244:I6G29_RS03575
uniprot id: A0A378XE21
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

90244:I6G29 RS01800
gene id: 90244:I6G29_RS01800
uniprot id: A0A378XBM6
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS13545
gene id: 90244:I6G29_RS13545
uniprot id: A0A378XAD8
names: Similarity
messages: Belongs to the GSP E family.

90244:I6G29 RS08725
gene id: 90244:I6G29_RS08725
uniprot id: A0A378XI02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

90244:I6G29 RS12540
gene id: 90244:I6G29_RS12540
uniprot id: A0A378XHU3
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

90244:I6G29 RS02230
gene id: 90244:I6G29_RS02230
uniprot id: A0A378XC19
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS12750
gene id: 90244:I6G29_RS12750
uniprot id: A0A378XIF9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

90244:I6G29 RS04735
gene id: 90244:I6G29_RS04735
uniprot id: A0A378XDT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

90244:I6G29 RS12080
gene id: 90244:I6G29_RS12080
uniprot id: A0A378XJ25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

90244:I6G29 RS05740
gene id: 90244:I6G29_RS05740
uniprot id: A0A378XDS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

90244:I6G29 RS02310
gene id: 90244:I6G29_RS02310
uniprot id: A0A378XE78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

90244:I6G29 RS04380
gene id: 90244:I6G29_RS04380
uniprot id: A0A378XDL3
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

90244:I6G29 RS01360
gene id: 90244:I6G29_RS01360
uniprot id: A0A378XAZ2
names: Similarity
messages: Belongs to the polysaccharide synthase family.

90244:I6G29 RS03655
gene id: 90244:I6G29_RS03655
uniprot id: A0A378XD53
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

90244:I6G29 RS03830
gene id: 90244:I6G29_RS03830
uniprot id: A0A378XFQ6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

90244:I6G29 RS07370
gene id: 90244:I6G29_RS07370
uniprot id: A0A378XG89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Membrane

90244:I6G29 RS07175
gene id: 90244:I6G29_RS07175
uniprot id: A0A378XG51
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS09310
gene id: 90244:I6G29_RS09310
uniprot id: A0A378XGI2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

90244:I6G29 RS06725
gene id: 90244:I6G29_RS06725
uniprot id: A0A378XGT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

90244:I6G29 RS11090
gene id: 90244:I6G29_RS11090
uniprot id: A0A378XII6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

90244:I6G29 RS10470
gene id: 90244:I6G29_RS10470
uniprot id: A0A378XH73
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

90244:I6G29 RS13315
gene id: 90244:I6G29_RS13315
uniprot id: A0A378XBB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

90244:I6G29 RS00965
gene id: 90244:I6G29_RS00965
uniprot id: A0A378XBN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

90244:I6G29 RS05205
gene id: 90244:I6G29_RS05205
uniprot id: A0A378XF12
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS12375
gene id: 90244:I6G29_RS12375
uniprot id: A0A378XJU4
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

90244:I6G29 RS05950
gene id: 90244:I6G29_RS05950
uniprot id: A0A378XFL0
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

90244:I6G29 RS07300
gene id: 90244:I6G29_RS07300
uniprot id: A0A378XFC7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS04420
gene id: 90244:I6G29_RS04420
uniprot id: A0A378XER8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

90244:I6G29 RS05245
gene id: 90244:I6G29_RS05245
uniprot id: A0A378XDI1
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

90244:I6G29 RS02530
gene id: 90244:I6G29_RS02530
uniprot id: A0A378XBV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

90244:I6G29 RS02120
gene id: 90244:I6G29_RS02120
uniprot id: A0A378XBF4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

90244:I6G29 RS08330
gene id: 90244:I6G29_RS08330
uniprot id: A0A378XI95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

90244:I6G29 RS02315
gene id: 90244:I6G29_RS02315
uniprot id: A0A378XEP2
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

90244:I6G29 RS07700
gene id: 90244:I6G29_RS07700
uniprot id: A0A378XGK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

90244:I6G29 RS06080
gene id: 90244:I6G29_RS06080
uniprot id: A0A378XH04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

90244:I6G29 RS01900
gene id: 90244:I6G29_RS01900
uniprot id: A0A378XDK8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

90244:I6G29 RS09920
gene id: 90244:I6G29_RS09920
uniprot id: A0A378XII9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

90244:I6G29 RS08810
gene id: 90244:I6G29_RS08810
uniprot id: A0A378XG71
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS11405
gene id: 90244:I6G29_RS11405
uniprot id: A0A378XGW2
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

90244:I6G29 RS06730
gene id: 90244:I6G29_RS06730
uniprot id: A0A378XGT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

90244:I6G29 RS03700
gene id: 90244:I6G29_RS03700
uniprot id: A0A378XEC4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-55 and Arg-58) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

90244:I6G29 RS12520
gene id: 90244:I6G29_RS12520
uniprot id: A0A378XJ68
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

90244:I6G29 RS06015
gene id: 90244:I6G29_RS06015
uniprot id: A0A378XDX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

90244:I6G29 RS04695
gene id: 90244:I6G29_RS04695
uniprot id: A0A378XFT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

90244:I6G29 RS09305
gene id: 90244:I6G29_RS09305
uniprot id: A0A378XHI6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

90244:I6G29 RS06055
gene id: 90244:I6G29_RS06055
uniprot id: A0A378XEM5
names: Similarity
messages: Belongs to the MlaA family.

90244:I6G29 RS11685
gene id: 90244:I6G29_RS11685
uniprot id: A0A378XHD1
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

90244:I6G29 RS02525
gene id: 90244:I6G29_RS02525
uniprot id: A0A378XCD6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

90244:I6G29 RS10040
gene id: 90244:I6G29_RS10040
uniprot id: A0A378XGV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

90244:I6G29 RS06340
gene id: 90244:I6G29_RS06340
uniprot id: A0A378XGL3
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

90244:I6G29 RS10815
gene id: 90244:I6G29_RS10815
uniprot id: A0A378XI73
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

90244:I6G29 RS08930
gene id: 90244:I6G29_RS08930
uniprot id: A0A378XH65
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

90244:I6G29 RS01050
gene id: 90244:I6G29_RS01050
uniprot id: A0A378XBH9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

90244:I6G29 RS10860
gene id: 90244:I6G29_RS10860
uniprot id: A0A378XJ65
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

90244:I6G29 RS03480
gene id: 90244:I6G29_RS03480
uniprot id: A0A378XF11
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

90244:I6G29 RS07240
gene id: 90244:I6G29_RS07240
uniprot id: A0A378XGA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

90244:I6G29 RS02450
gene id: 90244:I6G29_RS02450
uniprot id: A0A378XCD0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS04365
gene id: 90244:I6G29_RS04365
uniprot id: A0A378XDA7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

90244:I6G29 RS00095
gene id: 90244:I6G29_RS00095
uniprot id: A0A379B0U2
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS05100
gene id: 90244:I6G29_RS05100
uniprot id: A0A378XG23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

90244:I6G29 RS05210
gene id: 90244:I6G29_RS05210
uniprot id: A0A378XGJ0
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS10820
gene id: 90244:I6G29_RS10820
uniprot id: A0A378XJP5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

90244:I6G29 RS02630
gene id: 90244:I6G29_RS02630
uniprot id: A0A378XEG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.

90244:I6G29 RS03425
gene id: 90244:I6G29_RS03425
uniprot id: A0A378XFH9
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

90244:I6G29 RS10135
gene id: 90244:I6G29_RS10135
uniprot id: A0A378XH15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

90244:I6G29 RS10940
gene id: 90244:I6G29_RS10940
uniprot id: A0A378XIG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

90244:I6G29 RS03825
gene id: 90244:I6G29_RS03825
uniprot id: A0A378XE76
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

90244:I6G29 RS00700
gene id: 90244:I6G29_RS00700
uniprot id: A0A378XCA4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

90244:I6G29 RS07885
gene id: 90244:I6G29_RS07885
uniprot id: A0A378XI08
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

90244:I6G29 RS02930
gene id: 90244:I6G29_RS02930
uniprot id: A0A378XEP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

90244:I6G29 RS11420
gene id: 90244:I6G29_RS11420
uniprot id: A0A378XK30
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

90244:I6G29 RS12625
gene id: 90244:I6G29_RS12625
uniprot id: A0A378XKU1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

90244:I6G29 RS05795
gene id: 90244:I6G29_RS05795
uniprot id: A0A378XGF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

90244:I6G29 RS10915
gene id: 90244:I6G29_RS10915
uniprot id: A0A378XI89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

90244:I6G29 RS08510
gene id: 90244:I6G29_RS08510
uniprot id: A0A378XFZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

90244:I6G29 RS12470
gene id: 90244:I6G29_RS12470
uniprot id: A0A378XKM8
names: Similarity
messages: Belongs to the P(II) protein family.

90244:I6G29 RS00845
gene id: 90244:I6G29_RS00845
uniprot id: A0A378X9T2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

90244:I6G29 RS07935
gene id: 90244:I6G29_RS07935
uniprot id: A0A378XI17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

90244:I6G29 RS05275
gene id: 90244:I6G29_RS05275
uniprot id: A0A378XDT4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

90244:I6G29 RS03355
gene id: 90244:I6G29_RS03355
uniprot id: A0A378XCY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

90244:I6G29 RS05260
gene id: 90244:I6G29_RS05260
uniprot id: A0A378XGK1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

90244:I6G29 RS02890
gene id: 90244:I6G29_RS02890
uniprot id: A0A378XCE6
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

90244:I6G29 RS08680
gene id: 90244:I6G29_RS08680
uniprot id: A0A378XH14
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

90244:I6G29 RS05420
gene id: 90244:I6G29_RS05420
uniprot id: A0A378XG45
names: Subcellular Location Annotation
messages: target cell cytoplasm

90244:I6G29 RS03335
gene id: 90244:I6G29_RS03335
uniprot id: A0A378XEX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

90244:I6G29 RS07870
gene id: 90244:I6G29_RS07870
uniprot id: A0A378XEW5
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

90244:I6G29 RS07780
gene id: 90244:I6G29_RS07780
uniprot id: A0A378XGG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlhC family.
messages: Cytoplasm
messages: Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region.

90244:I6G29 RS01460
gene id: 90244:I6G29_RS01460
uniprot id: A0A378XD34
names: Similarity
messages: Belongs to the asparagine synthetase family.

90244:I6G29 RS03675
gene id: 90244:I6G29_RS03675
uniprot id: A0A378XE43
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

90244:I6G29 RS09670
gene id: 90244:I6G29_RS09670
uniprot id: A0A378XIJ2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

90244:I6G29 RS02875
gene id: 90244:I6G29_RS02875
uniprot id: A0A378XF72
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

90244:I6G29 RS00645
gene id: 90244:I6G29_RS00645
uniprot id: A0A378XB79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

90244:I6G29 RS00340
gene id: 90244:I6G29_RS00340
uniprot id: A0A378XBQ5
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

90244:I6G29 RS07660
gene id: 90244:I6G29_RS07660
uniprot id: A0A378XFH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

90244:I6G29 RS11875
gene id: 90244:I6G29_RS11875
uniprot id: A0A378XKB1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

90244:I6G29 RS07100
gene id: 90244:I6G29_RS07100
uniprot id: A0A378XH39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

90244:I6G29 RS10580
gene id: 90244:I6G29_RS10580
uniprot id: A0A378XGF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

90244:I6G29 RS05430
gene id: 90244:I6G29_RS05430
uniprot id: A0A378XFB0
names: Subcellular Location Annotation
messages: target cell cytoplasm

90244:I6G29 RS02255
gene id: 90244:I6G29_RS02255
uniprot id: A0A378XC47
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

90244:I6G29 RS03840
gene id: 90244:I6G29_RS03840
uniprot id: A0A378XF80
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

90244:I6G29 RS03175
gene id: 90244:I6G29_RS03175
uniprot id: A0A378XCK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

90244:I6G29 RS08530
gene id: 90244:I6G29_RS08530
uniprot id: A0A378XIE0
names: Similarity
messages: Belongs to the CutA family.

90244:I6G29 RS03525
gene id: 90244:I6G29_RS03525
uniprot id: A0A378XE12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

90244:I6G29 RS03950
gene id: 90244:I6G29_RS03950
uniprot id: A0A378XEH6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

90244:I6G29 RS07105
gene id: 90244:I6G29_RS07105
uniprot id: A0A378XG42
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

90244:I6G29 RS07710
gene id: 90244:I6G29_RS07710
uniprot id: A0A378XFI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

90244:I6G29 RS03320
gene id: 90244:I6G29_RS03320
uniprot id: A0A378XBF4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

90244:I6G29 RS05595
gene id: 90244:I6G29_RS05595
uniprot id: A0A378XGA7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

90244:I6G29 RS02010
gene id: 90244:I6G29_RS02010
uniprot id: A0A378XCU0
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS05970
gene id: 90244:I6G29_RS05970
uniprot id: A0A378XGI4
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

90244:I6G29 RS05080
gene id: 90244:I6G29_RS05080
uniprot id: A0A378XF47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

90244:I6G29 RS07685
gene id: 90244:I6G29_RS07685
uniprot id: A0A378XHD2
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS03615
gene id: 90244:I6G29_RS03615
uniprot id: A0A378XCJ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

90244:I6G29 RS12325
gene id: 90244:I6G29_RS12325
uniprot id: A0A378XJT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

90244:I6G29 RS09090
gene id: 90244:I6G29_RS09090
uniprot id: A0A378XI72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

90244:I6G29 RS12810
gene id: 90244:I6G29_RS12810
uniprot id: A0A378XHR7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

90244:I6G29 RS09730
gene id: 90244:I6G29_RS09730
uniprot id: A0A378XJ46
names: Similarity
messages: Belongs to the SCO1/2 family.

90244:I6G29 RS12225
gene id: 90244:I6G29_RS12225
uniprot id: A0A378XJR8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

90244:I6G29 RS08950
gene id: 90244:I6G29_RS08950
uniprot id: A0A378XFS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

90244:I6G29 RS12135
gene id: 90244:I6G29_RS12135
uniprot id: A0A378XJ36
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

90244:I6G29 RS03660
gene id: 90244:I6G29_RS03660
uniprot id: A0A378XD69
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

90244:I6G29 RS08495
gene id: 90244:I6G29_RS08495
uniprot id: A0A378XH08
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

90244:I6G29 RS08870
gene id: 90244:I6G29_RS08870
uniprot id: A0A378XFG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

90244:I6G29 RS06810
gene id: 90244:I6G29_RS06810
uniprot id: A0A378XFY5
names: Similarity
messages: Belongs to the RutC family.

90244:I6G29 RS06285
gene id: 90244:I6G29_RS06285
uniprot id: A0A378XGK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

90244:I6G29 RS06740
gene id: 90244:I6G29_RS06740
uniprot id: A0A378XG08
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

90244:I6G29 RS09770
gene id: 90244:I6G29_RS09770
uniprot id: A0A378XIL4
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS07400
gene id: 90244:I6G29_RS07400
uniprot id: A0A378XFE5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

90244:I6G29 RS08425
gene id: 90244:I6G29_RS08425
uniprot id: A0A378XGV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

90244:I6G29 RS07245
gene id: 90244:I6G29_RS07245
uniprot id: A0A378XFB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

90244:I6G29 RS02295
gene id: 90244:I6G29_RS02295
uniprot id: A0A378XE25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

90244:I6G29 RS12380
gene id: 90244:I6G29_RS12380
uniprot id: A0A378XHR5
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

90244:I6G29 RS00530
gene id: 90244:I6G29_RS00530
uniprot id: A0A378X9E1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

90244:I6G29 RS01440
gene id: 90244:I6G29_RS01440
uniprot id: A0A378XD30
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

90244:I6G29 RS09015
gene id: 90244:I6G29_RS09015
uniprot id: A0A378XG92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

90244:I6G29 RS06705
gene id: 90244:I6G29_RS06705
uniprot id: A0A378XEA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

90244:I6G29 RS10780
gene id: 90244:I6G29_RS10780
uniprot id: A0A378XIZ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

90244:I6G29 RS01565
gene id: 90244:I6G29_RS01565
uniprot id: A0A378XD49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

90244:I6G29 RS09020
gene id: 90244:I6G29_RS09020
uniprot id: A0A378XFK3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

90244:I6G29 RS00220
gene id: 90244:I6G29_RS00220
uniprot id: A0A378XAR0
names: Similarity
messages: Belongs to the DprA/Smf family.

90244:I6G29 RS08005
gene id: 90244:I6G29_RS08005
uniprot id: A0A378XGQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

90244:I6G29 RS01590
gene id: 90244:I6G29_RS01590
uniprot id: A0A378XDU6
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS02400
gene id: 90244:I6G29_RS02400
uniprot id: A0A378XDE2
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS08380
gene id: 90244:I6G29_RS08380
uniprot id: A0A378XIA6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

90244:I6G29 RS10865
gene id: 90244:I6G29_RS10865
uniprot id: A0A378XI80
names: Similarity
messages: Belongs to the fabD family.

90244:I6G29 RS10505
gene id: 90244:I6G29_RS10505
uniprot id: A0A378XIU8
names: Similarity
messages: Belongs to the universal stress protein A family.

90244:I6G29 RS09985
gene id: 90244:I6G29_RS09985
uniprot id: A0A378XGX9
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.

90244:I6G29 RS00795
gene id: 90244:I6G29_RS00795
uniprot id: A0A378XCV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

90244:I6G29 RS06960
gene id: 90244:I6G29_RS06960
uniprot id: A0A378XHH8
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

90244:I6G29 RS07450
gene id: 90244:I6G29_RS07450
uniprot id: A0A378XFF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

90244:I6G29 RS08580
gene id: 90244:I6G29_RS08580
uniprot id: A0A378XIF5
names: Similarity
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

90244:I6G29 RS04965
gene id: 90244:I6G29_RS04965
uniprot id: A0A378XFV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

90244:I6G29 RS13460
gene id: 90244:I6G29_RS13460
uniprot id: A0A378X9H0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

90244:I6G29 RS10995
gene id: 90244:I6G29_RS10995
uniprot id: A0A378XHH2
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

90244:I6G29 RS11805
gene id: 90244:I6G29_RS11805
uniprot id: A0A378XHT0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

90244:I6G29 RS07380
gene id: 90244:I6G29_RS07380
uniprot id: A0A378XH63
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

90244:I6G29 RS04625
gene id: 90244:I6G29_RS04625
uniprot id: A0A378XEV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

90244:I6G29 RS03280
gene id: 90244:I6G29_RS03280
uniprot id: A0A378XEW9
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

90244:I6G29 RS01550
gene id: 90244:I6G29_RS01550
uniprot id: A0A378XBB6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

90244:I6G29 RS11340
gene id: 90244:I6G29_RS11340
uniprot id: A0A378XIM9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

90244:I6G29 RS06865
gene id: 90244:I6G29_RS06865
uniprot id: A0A378XHF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

90244:I6G29 RS03010
gene id: 90244:I6G29_RS03010
uniprot id: A0A378XDX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

90244:I6G29 RS00975
gene id: 90244:I6G29_RS00975
uniprot id: A0A378XBE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

90244:I6G29 RS03770
gene id: 90244:I6G29_RS03770
uniprot id: A0A378XFB7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

90244:I6G29 RS00715
gene id: 90244:I6G29_RS00715
uniprot id: A0A378XA74
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS13405
gene id: 90244:I6G29_RS13405
uniprot id: A0A378X9F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

90244:I6G29 RS10720
gene id: 90244:I6G29_RS10720
uniprot id: A0A378XGG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

90244:I6G29 RS06760
gene id: 90244:I6G29_RS06760
uniprot id: A0A378XGZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

90244:I6G29 RS05280
gene id: 90244:I6G29_RS05280
uniprot id: A0A378XF83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

90244:I6G29 RS03590
gene id: 90244:I6G29_RS03590
uniprot id: A0A378XF28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

90244:I6G29 RS03180
gene id: 90244:I6G29_RS03180
uniprot id: A0A378XE14
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

90244:I6G29 RS12265
gene id: 90244:I6G29_RS12265
uniprot id: A0A378XKI6
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

90244:I6G29 RS04520
gene id: 90244:I6G29_RS04520
uniprot id: A0A378XDE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

90244:I6G29 RS03945
gene id: 90244:I6G29_RS03945
uniprot id: A0A378XD11
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

90244:I6G29 RS11640
gene id: 90244:I6G29_RS11640
uniprot id: A0A378XIT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

90244:I6G29 RS05250
gene id: 90244:I6G29_RS05250
uniprot id: A0A378XG44
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

90244:I6G29 RS13220
gene id: 90244:I6G29_RS13220
uniprot id: A0A378XIP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

90244:I6G29 RS02900
gene id: 90244:I6G29_RS02900
uniprot id: A0A378XCS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

90244:I6G29 RS08755
gene id: 90244:I6G29_RS08755
uniprot id: A0A378XH66
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

90244:I6G29 RS06910
gene id: 90244:I6G29_RS06910
uniprot id: A0A378XHG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

90244:I6G29 RS07945
gene id: 90244:I6G29_RS07945
uniprot id: A0A378XHE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

90244:I6G29 RS08985
gene id: 90244:I6G29_RS08985
uniprot id: A0A378XIN7
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

90244:I6G29 RS10870
gene id: 90244:I6G29_RS10870
uniprot id: A0A378XJR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

90244:I6G29 RS07305
gene id: 90244:I6G29_RS07305
uniprot id: A0A378XF93
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

90244:I6G29 RS06005
gene id: 90244:I6G29_RS06005
uniprot id: A0A378XEL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

90244:I6G29 RS12465
gene id: 90244:I6G29_RS12465
uniprot id: A0A378XJ59
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: In the C-terminal section; belongs to the NAD synthetase family.

90244:I6G29 RS12345
gene id: 90244:I6G29_RS12345
uniprot id: A0A378XI48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

90244:I6G29 RS12980
gene id: 90244:I6G29_RS12980
uniprot id: A0A378XKD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

90244:I6G29 RS09035
gene id: 90244:I6G29_RS09035
uniprot id: A0A378XIP8
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

90244:I6G29 RS05550
gene id: 90244:I6G29_RS05550
uniprot id: A0A378XF81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

90244:I6G29 RS00760
gene id: 90244:I6G29_RS00760
uniprot id: A0A378XAA0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

90244:I6G29 RS04300
gene id: 90244:I6G29_RS04300
uniprot id: A0A378XFZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

90244:I6G29 RS11300
gene id: 90244:I6G29_RS11300
uniprot id: A0A378XHI3
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

90244:I6G29 RS12565
gene id: 90244:I6G29_RS12565
uniprot id: A0A378XK59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

90244:I6G29 RS08335
gene id: 90244:I6G29_RS08335
uniprot id: A0A378XHQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

90244:I6G29 RS10200
gene id: 90244:I6G29_RS10200
uniprot id: A0A378XIU9
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

90244:I6G29 RS04355
gene id: 90244:I6G29_RS04355
uniprot id: A0A378XFI9
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

90244:I6G29 RS11905
gene id: 90244:I6G29_RS11905
uniprot id: A0A378XH78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

90244:I6G29 RS05065
gene id: 90244:I6G29_RS05065
uniprot id: A0A378XFZ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

90244:I6G29 RS02685
gene id: 90244:I6G29_RS02685
uniprot id: A0A378XEH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

90244:I6G29 RS10045
gene id: 90244:I6G29_RS10045
uniprot id: A0A378XG52
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

90244:I6G29 RS05845
gene id: 90244:I6G29_RS05845
uniprot id: A0A378XFE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

90244:I6G29 RS05985
gene id: 90244:I6G29_RS05985
uniprot id: A0A378XGE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

90244:I6G29 RS06155
gene id: 90244:I6G29_RS06155
uniprot id: A0A378XEP5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS13190
gene id: 90244:I6G29_RS13190
uniprot id: A0A378XJJ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

90244:I6G29 RS03850
gene id: 90244:I6G29_RS03850
uniprot id: A0A378XEF3
names: Similarity
messages: Belongs to the barstar family.

90244:I6G29 RS10965
gene id: 90244:I6G29_RS10965
uniprot id: A0A378XIA1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

90244:I6G29 RS11860
gene id: 90244:I6G29_RS11860
uniprot id: A0A378XH68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

90244:I6G29 RS10055
gene id: 90244:I6G29_RS10055
uniprot id: A0A378XHU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

90244:I6G29 RS13350
gene id: 90244:I6G29_RS13350
uniprot id: A0A378XB96
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

90244:I6G29 RS08575
gene id: 90244:I6G29_RS08575
uniprot id: A0A378XGY6
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

90244:I6G29 RS08290
gene id: 90244:I6G29_RS08290
uniprot id: A0A378XFE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

90244:I6G29 RS06710
gene id: 90244:I6G29_RS06710
uniprot id: A0A378XGY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

90244:I6G29 RS00505
gene id: 90244:I6G29_RS00505
uniprot id: A0A378X9Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

90244:I6G29 RS13165
gene id: 90244:I6G29_RS13165
uniprot id: A0A378XJM8
names: Similarity
messages: Belongs to the IMPACT family.

90244:I6G29 RS12100
gene id: 90244:I6G29_RS12100
uniprot id: A0A378XHB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

90244:I6G29 RS10960
gene id: 90244:I6G29_RS10960
uniprot id: A0A378XJ86
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

90244:I6G29 RS10785
gene id: 90244:I6G29_RS10785
uniprot id: A0A378XGT5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS10105
gene id: 90244:I6G29_RS10105
uniprot id: A0A378XJD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

90244:I6G29 RS11900
gene id: 90244:I6G29_RS11900
uniprot id: A0A378XHV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

90244:I6G29 RS00360
gene id: 90244:I6G29_RS00360
uniprot id: A0A378XAL4
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

90244:I6G29 RS10320
gene id: 90244:I6G29_RS10320
uniprot id: A0A378XIW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

90244:I6G29 RS00940
gene id: 90244:I6G29_RS00940
uniprot id: A0A378XA71
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

90244:I6G29 RS12765
gene id: 90244:I6G29_RS12765
uniprot id: A0A378XK98
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

90244:I6G29 RS11355
gene id: 90244:I6G29_RS11355
uniprot id: A0A378XGV1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

90244:I6G29 RS03290
gene id: 90244:I6G29_RS03290
uniprot id: A0A378XCM2
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

90244:I6G29 RS13495
gene id: 90244:I6G29_RS13495
uniprot id: A0A378XAB5
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

90244:I6G29 RS00670
gene id: 90244:I6G29_RS00670
uniprot id: A0A378XA68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

90244:I6G29 RS06540
gene id: 90244:I6G29_RS06540
uniprot id: A0A378XGP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

90244:I6G29 RS10010
gene id: 90244:I6G29_RS10010
uniprot id: A0A378XJB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

90244:I6G29 RS08020
gene id: 90244:I6G29_RS08020
uniprot id: A0A378XEZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

90244:I6G29 RS04985
gene id: 90244:I6G29_RS04985
uniprot id: A0A378XDZ9
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

90244:I6G29 RS11605
gene id: 90244:I6G29_RS11605
uniprot id: A0A378XH21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

90244:I6G29 RS04605
gene id: 90244:I6G29_RS04605
uniprot id: A0A378XG59
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

90244:I6G29 RS09960
gene id: 90244:I6G29_RS09960
uniprot id: A0A378XJA2
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

90244:I6G29 RS00785
gene id: 90244:I6G29_RS00785
uniprot id: A0A378X9R3
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS10540
gene id: 90244:I6G29_RS10540
uniprot id: A0A378XI24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

90244:I6G29 RS04820
gene id: 90244:I6G29_RS04820
uniprot id: A0A378XDJ8
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS08955
gene id: 90244:I6G29_RS08955
uniprot id: A0A378XHB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

90244:I6G29 RS12395
gene id: 90244:I6G29_RS12395
uniprot id: A0A378XI55
names: Cofactor
messages: Can also use Mn(2+) ion.

90244:I6G29 RS05755
gene id: 90244:I6G29_RS05755
uniprot id: A0A378XGV0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

90244:I6G29 RS02475
gene id: 90244:I6G29_RS02475
uniprot id: A0A378XCD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

90244:I6G29 RS11440
gene id: 90244:I6G29_RS11440
uniprot id: A0A378XIQ0
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

90244:I6G29 RS10175
gene id: 90244:I6G29_RS10175
uniprot id: A0A378XGI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

90244:I6G29 RS08615
gene id: 90244:I6G29_RS08615
uniprot id: A0A378XFB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

90244:I6G29 RS12755
gene id: 90244:I6G29_RS12755
uniprot id: A0A378XIC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PriB family.
messages: Binds single-stranded DNA at the primosome assembly site (PAS).
messages: Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome.

90244:I6G29 RS13185
gene id: 90244:I6G29_RS13185
uniprot id: A0A378XKI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

90244:I6G29 RS02460
gene id: 90244:I6G29_RS02460
uniprot id: A0A378XD97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

90244:I6G29 RS11535
gene id: 90244:I6G29_RS11535
uniprot id: A0A378XIR9
names: Similarity
messages: Belongs to the WrbA family.

90244:I6G29 RS13695
gene id: 90244:I6G29_RS13695
uniprot id: A0A378XGM0
names: Subcellular Location Annotation
messages: target cell cytoplasm

90244:I6G29 RS12400
gene id: 90244:I6G29_RS12400
uniprot id: A0A378XHH7
names: Similarity
messages: Belongs to the FrmR/RcnR family.

90244:I6G29 RS12020
gene id: 90244:I6G29_RS12020
uniprot id: A0A378XJM9
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS00710
gene id: 90244:I6G29_RS00710
uniprot id: A0A378X9W6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS00520
gene id: 90244:I6G29_RS00520
uniprot id: A0A378X9M8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

90244:I6G29 RS13255
gene id: 90244:I6G29_RS13255
uniprot id: A0A378XB58
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

90244:I6G29 RS12155
gene id: 90244:I6G29_RS12155
uniprot id: A0A378XJX2
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

90244:I6G29 RS00350
gene id: 90244:I6G29_RS00350
uniprot id: A0A378X9T4
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

90244:I6G29 RS13095
gene id: 90244:I6G29_RS13095
uniprot id: A0A378XL32
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

90244:I6G29 RS01250
gene id: 90244:I6G29_RS01250
uniprot id: A0A378XAA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

90244:I6G29 RS11125
gene id: 90244:I6G29_RS11125
uniprot id: A0A378XJA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

90244:I6G29 RS02260
gene id: 90244:I6G29_RS02260
uniprot id: A0A378XBJ0
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

90244:I6G29 RS02940
gene id: 90244:I6G29_RS02940
uniprot id: A0A378XCF8
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Oligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.

90244:I6G29 RS11585
gene id: 90244:I6G29_RS11585
uniprot id: A0A378XHB1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

90244:I6G29 RS01390
gene id: 90244:I6G29_RS01390
uniprot id: A0A378XDK3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

90244:I6G29 RS11365
gene id: 90244:I6G29_RS11365
uniprot id: A0A378XII3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

90244:I6G29 RS08855
gene id: 90244:I6G29_RS08855
uniprot id: A0A378XH96
names: Similarity
messages: Belongs to the TrpC family.

90244:I6G29 RS00445
gene id: 90244:I6G29_RS00445
uniprot id: A0A378XBS3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

90244:I6G29 RS03490
gene id: 90244:I6G29_RS03490
uniprot id: A0A378XCR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

90244:I6G29 RS13550
gene id: 90244:I6G29_RS13550
uniprot id: A0A378XBI7
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS05600
gene id: 90244:I6G29_RS05600
uniprot id: A0A378XF90
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS12295
gene id: 90244:I6G29_RS12295
uniprot id: A0A378XI31
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

90244:I6G29 RS09230
gene id: 90244:I6G29_RS09230
uniprot id: A0A378XIA2
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS09390
gene id: 90244:I6G29_RS09390
uniprot id: A0A378XID1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

90244:I6G29 RS00305
gene id: 90244:I6G29_RS00305
uniprot id: A0A378XBT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

90244:I6G29 RS07160
gene id: 90244:I6G29_RS07160
uniprot id: A0A378XF64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

90244:I6G29 RS02270
gene id: 90244:I6G29_RS02270
uniprot id: A0A378XE15
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

90244:I6G29 RS01010
gene id: 90244:I6G29_RS01010
uniprot id: A0A378XCI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

90244:I6G29 RS06065
gene id: 90244:I6G29_RS06065
uniprot id: A0A378XDY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

90244:I6G29 RS06010
gene id: 90244:I6G29_RS06010
uniprot id: A0A378XEJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

90244:I6G29 RS00580
gene id: 90244:I6G29_RS00580
uniprot id: A0A378XC52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

90244:I6G29 RS06565
gene id: 90244:I6G29_RS06565
uniprot id: A0A378XEU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

90244:I6G29 RS08475
gene id: 90244:I6G29_RS08475
uniprot id: A0A378XGW4
names: Similarity
messages: Belongs to the UPF0423 family.

90244:I6G29 RS06450
gene id: 90244:I6G29_RS06450
uniprot id: A0A378XFV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

90244:I6G29 RS00600
gene id: 90244:I6G29_RS00600
uniprot id: A0A378X9G9
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

90244:I6G29 RS01260
gene id: 90244:I6G29_RS01260
uniprot id: A0A378XCR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

90244:I6G29 RS09185
gene id: 90244:I6G29_RS09185
uniprot id: A0A378XI43
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

90244:I6G29 RS07785
gene id: 90244:I6G29_RS07785
uniprot id: A0A378XHY9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

90244:I6G29 RS11850
gene id: 90244:I6G29_RS11850
uniprot id: A0A378XHX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

90244:I6G29 RS11855
gene id: 90244:I6G29_RS11855
uniprot id: A0A378XHT9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

90244:I6G29 RS08620
gene id: 90244:I6G29_RS08620
uniprot id: A0A378XHY2
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS00995
gene id: 90244:I6G29_RS00995
uniprot id: A0A378XA09
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

90244:I6G29 RS04765
gene id: 90244:I6G29_RS04765
uniprot id: A0A378XFQ9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

90244:I6G29 RS03375
gene id: 90244:I6G29_RS03375
uniprot id: A0A378XFH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

90244:I6G29 RS02355
gene id: 90244:I6G29_RS02355
uniprot id: A0A378XEA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

90244:I6G29 RS08280
gene id: 90244:I6G29_RS08280
uniprot id: A0A378XHQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

90244:I6G29 RS00435
gene id: 90244:I6G29_RS00435
uniprot id: A0A378XBY7
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS04640
gene id: 90244:I6G29_RS04640
uniprot id: A0A378XD62
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Maintains high levels of reduced glutathione.

90244:I6G29 RS05965
gene id: 90244:I6G29_RS05965
uniprot id: A0A378XDW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

90244:I6G29 RS06890
gene id: 90244:I6G29_RS06890
uniprot id: A0A378XF09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

90244:I6G29 RS08885
gene id: 90244:I6G29_RS08885
uniprot id: A0A378XIL7
names: Similarity
messages: Belongs to the PrpF family.

90244:I6G29 RS08270
gene id: 90244:I6G29_RS08270
uniprot id: A0A378XGS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

90244:I6G29 RS13415
gene id: 90244:I6G29_RS13415
uniprot id: A0A378XBZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

90244:I6G29 RS00730
gene id: 90244:I6G29_RS00730
uniprot id: A0A378XC39
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

90244:I6G29 RS11620
gene id: 90244:I6G29_RS11620
uniprot id: A0A378XK61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

90244:I6G29 RS05980
gene id: 90244:I6G29_RS05980
uniprot id: A0A378XGZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

90244:I6G29 RS07285
gene id: 90244:I6G29_RS07285
uniprot id: A0A378XH38
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

90244:I6G29 RS09060
gene id: 90244:I6G29_RS09060
uniprot id: A0A378XGD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

90244:I6G29 RS08315
gene id: 90244:I6G29_RS08315
uniprot id: A0A378XHS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

90244:I6G29 RS03400
gene id: 90244:I6G29_RS03400
uniprot id: A0A378XD25
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

90244:I6G29 RS07880
gene id: 90244:I6G29_RS07880
uniprot id: A0A378XGI8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

90244:I6G29 RS09785
gene id: 90244:I6G29_RS09785
uniprot id: A0A378XIL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

90244:I6G29 RS02445
gene id: 90244:I6G29_RS02445
uniprot id: A0A378XC11
names: Function
names: Similarity
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.

90244:I6G29 RS03135
gene id: 90244:I6G29_RS03135
uniprot id: A0A378XE02
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

90244:I6G29 RS08880
gene id: 90244:I6G29_RS08880
uniprot id: A0A378XH51
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

90244:I6G29 RS13295
gene id: 90244:I6G29_RS13295
uniprot id: A0A378XA35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

90244:I6G29 RS02290
gene id: 90244:I6G29_RS02290
uniprot id: A0A378XEN2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

90244:I6G29 RS02945
gene id: 90244:I6G29_RS02945
uniprot id: A0A378XDW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein.
messages: Oligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.

90244:I6G29 RS06530
gene id: 90244:I6G29_RS06530
uniprot id: A0A378XFS8
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.
messages: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
messages: The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.

90244:I6G29 RS02385
gene id: 90244:I6G29_RS02385
uniprot id: A0A378XES2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

90244:I6G29 RS09415
gene id: 90244:I6G29_RS09415
uniprot id: A0A378XGI0
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

90244:I6G29 RS00980
gene id: 90244:I6G29_RS00980
uniprot id: A0A378XCH8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

90244:I6G29 RS08000
gene id: 90244:I6G29_RS08000
uniprot id: A0A378XF89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

90244:I6G29 RS04440
gene id: 90244:I6G29_RS04440
uniprot id: A0A378XFN5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

90244:I6G29 RS11940
gene id: 90244:I6G29_RS11940
uniprot id: A0A378XHZ8
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

90244:I6G29 RS09195
gene id: 90244:I6G29_RS09195
uniprot id: A0A378XHG5
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS13320
gene id: 90244:I6G29_RS13320
uniprot id: A0A378XBW0
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

90244:I6G29 RS02695
gene id: 90244:I6G29_RS02695
uniprot id: A0A378XCM3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

90244:I6G29 RS01985
gene id: 90244:I6G29_RS01985
uniprot id: A0A378XB98
names: Subunit
messages: Homodimer.

90244:I6G29 RS02410
gene id: 90244:I6G29_RS02410
uniprot id: A0A378XD79
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

90244:I6G29 RS04685
gene id: 90244:I6G29_RS04685
uniprot id: A0A378XDS8
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

90244:I6G29 RS10910
gene id: 90244:I6G29_RS10910
uniprot id: A0A378XJ75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

90244:I6G29 RS06255
gene id: 90244:I6G29_RS06255
uniprot id: A0A378XER4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

90244:I6G29 RS08310
gene id: 90244:I6G29_RS08310
uniprot id: A0A378XF51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

90244:I6G29 RS00570
gene id: 90244:I6G29_RS00570
uniprot id: A0A378X9P9
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

90244:I6G29 RS04090
gene id: 90244:I6G29_RS04090
uniprot id: A0A378XFD3
names: Subcellular Location Annotation
messages: Cell inner membrane

90244:I6G29 RS00515
gene id: 90244:I6G29_RS00515
uniprot id: A0A378XBX6
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

90244:I6G29 RS04370
gene id: 90244:I6G29_RS04370
uniprot id: A0A378XEQ8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

90244:I6G29 RS12335
gene id: 90244:I6G29_RS12335
uniprot id: A0A378XJ71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

90244:I6G29 RS02805
gene id: 90244:I6G29_RS02805
uniprot id: A0A378XER9
names: Function
names: Subcellular Location Annotation
messages: Involved in mercury resistance. Acts as a mercury scavenger that specifically binds to a mercuric ion in the periplasm and probably passes it to the cytoplasmic mercuric reductase MerA via the mercuric transport protein MerT.
messages: Periplasm

90244:I6G29 RS01165
gene id: 90244:I6G29_RS01165
uniprot id: A0A378XCV1
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS11700
gene id: 90244:I6G29_RS11700
uniprot id: A0A378XHR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

90244:I6G29 RS11680
gene id: 90244:I6G29_RS11680
uniprot id: A0A378XJF5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

90244:I6G29 RS04335
gene id: 90244:I6G29_RS04335
uniprot id: A0A378XCY9
names: Similarity
messages: Belongs to the DEAD box helicase family.

90244:I6G29 RS13215
gene id: 90244:I6G29_RS13215
uniprot id: A0A378XJN6
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

90244:I6G29 RS00575
gene id: 90244:I6G29_RS00575
uniprot id: A0A378XA29
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

90244:I6G29 RS04045
gene id: 90244:I6G29_RS04045
uniprot id: A0A378XFC4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

90244:I6G29 RS00500
gene id: 90244:I6G29_RS00500
uniprot id: A0A378XB20
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

90244:I6G29 RS11150
gene id: 90244:I6G29_RS11150
uniprot id: A0A378XHE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

90244:I6G29 RS08585
gene id: 90244:I6G29_RS08585
uniprot id: A0A378XHV8
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

90244:I6G29 RS04945
gene id: 90244:I6G29_RS04945
uniprot id: A0A378XDY8
names: Caution
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS00695
gene id: 90244:I6G29_RS00695
uniprot id: A0A378XA63
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

90244:I6G29 RS10760
gene id: 90244:I6G29_RS10760
uniprot id: A0A378XJ42
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

90244:I6G29 RS11750
gene id: 90244:I6G29_RS11750
uniprot id: A0A378XHS2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

90244:I6G29 RS11705
gene id: 90244:I6G29_RS11705
uniprot id: A0A378XH42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

90244:I6G29 RS04410
gene id: 90244:I6G29_RS04410
uniprot id: A0A378XFJ1
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS07845
gene id: 90244:I6G29_RS07845
uniprot id: A0A378XHD3
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

90244:I6G29 RS11580
gene id: 90244:I6G29_RS11580
uniprot id: A0A378XJD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

90244:I6G29 RS01195
gene id: 90244:I6G29_RS01195
uniprot id: A0A378XBP7
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS13355
gene id: 90244:I6G29_RS13355
uniprot id: A0A378X8X0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

90244:I6G29 RS02605
gene id: 90244:I6G29_RS02605
uniprot id: A0A378XEF7
names: Similarity
messages: Belongs to the citrate synthase family.

90244:I6G29 RS08745
gene id: 90244:I6G29_RS08745
uniprot id: A0A378XHV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

90244:I6G29 RS03810
gene id: 90244:I6G29_RS03810
uniprot id: A0A378XD98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

90244:I6G29 RS01490
gene id: 90244:I6G29_RS01490
uniprot id: A0A378XAL9
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

90244:I6G29 RS00440
gene id: 90244:I6G29_RS00440
uniprot id: A0A378XAQ2
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS11145
gene id: 90244:I6G29_RS11145
uniprot id: A0A378XHK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Membrane

90244:I6G29 RS11615
gene id: 90244:I6G29_RS11615
uniprot id: A0A378XIN0
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

90244:I6G29 RS03845
gene id: 90244:I6G29_RS03845
uniprot id: A0A378XCZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

90244:I6G29 RS05230
gene id: 90244:I6G29_RS05230
uniprot id: A0A378XF73
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.

90244:I6G29 RS00865
gene id: 90244:I6G29_RS00865
uniprot id: A0A378XAF1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

90244:I6G29 RS12555
gene id: 90244:I6G29_RS12555
uniprot id: A0A378XI87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

90244:I6G29 RS11155
gene id: 90244:I6G29_RS11155
uniprot id: A0A378XGR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

90244:I6G29 RS08160
gene id: 90244:I6G29_RS08160
uniprot id: A0A378XGQ3
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS09620
gene id: 90244:I6G29_RS09620
uniprot id: A0A378XII5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

90244:I6G29 RS02905
gene id: 90244:I6G29_RS02905
uniprot id: A0A378XCP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

90244:I6G29 RS06195
gene id: 90244:I6G29_RS06195
uniprot id: A0A378XE97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

90244:I6G29 RS08215
gene id: 90244:I6G29_RS08215
uniprot id: A0A378XHQ7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

90244:I6G29 RS10900
gene id: 90244:I6G29_RS10900
uniprot id: A0A378XHA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

90244:I6G29 RS06945
gene id: 90244:I6G29_RS06945
uniprot id: A0A378XEE9
names: Similarity
messages: Belongs to the PrpD family.

90244:I6G29 RS02870
gene id: 90244:I6G29_RS02870
uniprot id: A0A378XDN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

90244:I6G29 RS07025
gene id: 90244:I6G29_RS07025
uniprot id: A0A378XEQ7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

90244:I6G29 RS07440
gene id: 90244:I6G29_RS07440
uniprot id: A0A378XEY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

90244:I6G29 RS03600
gene id: 90244:I6G29_RS03600
uniprot id: A0A378XEA3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

90244:I6G29 RS06665
gene id: 90244:I6G29_RS06665
uniprot id: A0A378XGX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

90244:I6G29 RS11555
gene id: 90244:I6G29_RS11555
uniprot id: A0A378XJL0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

90244:I6G29 RS10525
gene id: 90244:I6G29_RS10525
uniprot id: A0A378XH40
names: Similarity
messages: Belongs to the class-I fumarase family.

90244:I6G29 RS12085
gene id: 90244:I6G29_RS12085
uniprot id: A0A378XI22
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS10880
gene id: 90244:I6G29_RS10880
uniprot id: A0A378XJ10
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

90244:I6G29 RS12680
gene id: 90244:I6G29_RS12680
uniprot id: A0A378XK60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

90244:I6G29 RS03715
gene id: 90244:I6G29_RS03715
uniprot id: A0A378XCL2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS08660
gene id: 90244:I6G29_RS08660
uniprot id: A0A378XG22
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

90244:I6G29 RS08505
gene id: 90244:I6G29_RS08505
uniprot id: A0A378XG13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

90244:I6G29 RS07600
gene id: 90244:I6G29_RS07600
uniprot id: A0A378XGI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

90244:I6G29 RS01140
gene id: 90244:I6G29_RS01140
uniprot id: A0A378XCU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

90244:I6G29 RS12930
gene id: 90244:I6G29_RS12930
uniprot id: A0A378XKZ7
names: Function
messages: Abolishes the inhibitory effect of tetracyclin on protein synthesis by a non-covalent modification of the ribosomes.

90244:I6G29 RS11055
gene id: 90244:I6G29_RS11055
uniprot id: A0A378XGP0
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS10555
gene id: 90244:I6G29_RS10555
uniprot id: A0A378XIV4
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS06395
gene id: 90244:I6G29_RS06395
uniprot id: A0A378XGM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TraY family.
messages: Cytoplasm

90244:I6G29 RS07965
gene id: 90244:I6G29_RS07965
uniprot id: A0A378XFM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

90244:I6G29 RS05070
gene id: 90244:I6G29_RS05070
uniprot id: A0A378XFX3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS08600
gene id: 90244:I6G29_RS08600
uniprot id: A0A378XH35
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

90244:I6G29 RS10850
gene id: 90244:I6G29_RS10850
uniprot id: A0A378XH94
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

90244:I6G29 RS11840
gene id: 90244:I6G29_RS11840
uniprot id: A0A378XHG2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

90244:I6G29 RS12175
gene id: 90244:I6G29_RS12175
uniprot id: A0A378XJQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

90244:I6G29 RS12125
gene id: 90244:I6G29_RS12125
uniprot id: A0A378XJP6
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS12560
gene id: 90244:I6G29_RS12560
uniprot id: A0A378XHK7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

90244:I6G29 RS02700
gene id: 90244:I6G29_RS02700
uniprot id: A0A378XC06
names: Similarity
messages: Belongs to the HIBADH-related family.

90244:I6G29 RS00650
gene id: 90244:I6G29_RS00650
uniprot id: A0A378XA51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

90244:I6G29 RS06535
gene id: 90244:I6G29_RS06535
uniprot id: A0A378XH90
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

90244:I6G29 RS07925
gene id: 90244:I6G29_RS07925
uniprot id: A0A378XHJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

90244:I6G29 RS04375
gene id: 90244:I6G29_RS04375
uniprot id: A0A378XDL5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

90244:I6G29 RS01375
gene id: 90244:I6G29_RS01375
uniprot id: A0A378XC64
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

90244:I6G29 RS03310
gene id: 90244:I6G29_RS03310
uniprot id: A0A378XCC9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS01315
gene id: 90244:I6G29_RS01315
uniprot id: A0A378XAE0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

90244:I6G29 RS08815
gene id: 90244:I6G29_RS08815
uniprot id: A0A378XG55
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS04310
gene id: 90244:I6G29_RS04310
uniprot id: A0A378XFH3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

90244:I6G29 RS08265
gene id: 90244:I6G29_RS08265
uniprot id: A0A378XHR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

90244:I6G29 RS00690
gene id: 90244:I6G29_RS00690
uniprot id: A0A378XBA1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

90244:I6G29 RS00030
gene id: 90244:I6G29_RS00030
uniprot id: A0A379B137
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cell inner membrane
messages: Part of the Type IV secretion system.

90244:I6G29 RS08255
gene id: 90244:I6G29_RS08255
uniprot id: A0A378XFU3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

90244:I6G29 RS06900
gene id: 90244:I6G29_RS06900
uniprot id: A0A378XH06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

90244:I6G29 RS02625
gene id: 90244:I6G29_RS02625
uniprot id: A0A378XDG5
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

90244:I6G29 RS04860
gene id: 90244:I6G29_RS04860
uniprot id: A0A378XGC3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

90244:I6G29 RS04730
gene id: 90244:I6G29_RS04730
uniprot id: A0A378XDV1
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

90244:I6G29 RS09760
gene id: 90244:I6G29_RS09760
uniprot id: A0A378XGQ1
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

90244:I6G29 RS04600
gene id: 90244:I6G29_RS04600
uniprot id: A0A378XEP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

90244:I6G29 RS09740
gene id: 90244:I6G29_RS09740
uniprot id: A0A378XIF3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

90244:I6G29 RS03605
gene id: 90244:I6G29_RS03605
uniprot id: A0A378XD46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

90244:I6G29 RS03160
gene id: 90244:I6G29_RS03160
uniprot id: A0A378XDT9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS10665
gene id: 90244:I6G29_RS10665
uniprot id: A0A378XI46
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

90244:I6G29 RS00315
gene id: 90244:I6G29_RS00315
uniprot id: A0A378XBM1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS11100
gene id: 90244:I6G29_RS11100
uniprot id: A0A378XHD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

90244:I6G29 RS05575
gene id: 90244:I6G29_RS05575
uniprot id: A0A378XFE3
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS12445
gene id: 90244:I6G29_RS12445
uniprot id: A0A378XI97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

90244:I6G29 RS02305
gene id: 90244:I6G29_RS02305
uniprot id: A0A378XC54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

90244:I6G29 RS00300
gene id: 90244:I6G29_RS00300
uniprot id: A0A378X949
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

90244:I6G29 RS03140
gene id: 90244:I6G29_RS03140
uniprot id: A0A378XCX8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

90244:I6G29 RS09100
gene id: 90244:I6G29_RS09100
uniprot id: A0A378XFV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

90244:I6G29 RS09545
gene id: 90244:I6G29_RS09545
uniprot id: A0A378XIB2
names: Subcellular Location Annotation
messages: Mitochondrion

90244:I6G29 RS07035
gene id: 90244:I6G29_RS07035
uniprot id: A0A378XF76
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

90244:I6G29 RS10510
gene id: 90244:I6G29_RS10510
uniprot id: A0A378XGP2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

90244:I6G29 RS05125
gene id: 90244:I6G29_RS05125
uniprot id: A0A378XDQ7
names: Similarity
messages: Belongs to the peptidase U62 family.

90244:I6G29 RS07115
gene id: 90244:I6G29_RS07115
uniprot id: A0A378XH16
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS00425
gene id: 90244:I6G29_RS00425
uniprot id: A0A378XAY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

90244:I6G29 RS10790
gene id: 90244:I6G29_RS10790
uniprot id: A0A378XID5
names: Similarity
messages: Belongs to the UPF0246 family.

90244:I6G29 RS03610
gene id: 90244:I6G29_RS03610
uniprot id: A0A378XD58
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

90244:I6G29 RS04345
gene id: 90244:I6G29_RS04345
uniprot id: A0A378XEI9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

90244:I6G29 RS11185
gene id: 90244:I6G29_RS11185
uniprot id: A0A378XH25
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

90244:I6G29 RS07095
gene id: 90244:I6G29_RS07095
uniprot id: A0A378XEH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

90244:I6G29 RS08535
gene id: 90244:I6G29_RS08535
uniprot id: A0A378XHU9
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

90244:I6G29 RS12815
gene id: 90244:I6G29_RS12815
uniprot id: A0A378XKA7
names: Caution
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS01075
gene id: 90244:I6G29_RS01075
uniprot id: A0A378XD61
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

90244:I6G29 RS04245
gene id: 90244:I6G29_RS04245
uniprot id: A0A378XEG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

90244:I6G29 RS07630
gene id: 90244:I6G29_RS07630
uniprot id: A0A378XHV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

90244:I6G29 RS12315
gene id: 90244:I6G29_RS12315
uniprot id: A0A378XKJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

90244:I6G29 RS13665
gene id: 90244:I6G29_RS13665
uniprot id: A0A378XDU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

90244:I6G29 RS05880
gene id: 90244:I6G29_RS05880
uniprot id: A0A378XEH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

90244:I6G29 RS11505
gene id: 90244:I6G29_RS11505
uniprot id: A0A378XJJ6
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

90244:I6G29 RS04280
gene id: 90244:I6G29_RS04280
uniprot id: A0A378XDJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

90244:I6G29 RS05615
gene id: 90244:I6G29_RS05615
uniprot id: A0A378XG84
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

90244:I6G29 RS11950
gene id: 90244:I6G29_RS11950
uniprot id: A0A378XH88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

90244:I6G29 RS08525
gene id: 90244:I6G29_RS08525
uniprot id: A0A378XGX3
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS02205
gene id: 90244:I6G29_RS02205
uniprot id: A0A378XC12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

90244:I6G29 RS01275
gene id: 90244:I6G29_RS01275
uniprot id: A0A378XCZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

90244:I6G29 RS07125
gene id: 90244:I6G29_RS07125
uniprot id: A0A378XH06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

90244:I6G29 RS10675
gene id: 90244:I6G29_RS10675
uniprot id: A0A378XJ24
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

90244:I6G29 RS10550
gene id: 90244:I6G29_RS10550
uniprot id: A0A378XJ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

90244:I6G29 RS09950
gene id: 90244:I6G29_RS09950
uniprot id: A0A378XIP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

90244:I6G29 RS07155
gene id: 90244:I6G29_RS07155
uniprot id: A0A378XF98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

90244:I6G29 RS03585
gene id: 90244:I6G29_RS03585
uniprot id: A0A378XF33
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

90244:I6G29 RS07030
gene id: 90244:I6G29_RS07030
uniprot id: A0A378XG66
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS06965
gene id: 90244:I6G29_RS06965
uniprot id: A0A378XGZ0
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS07530
gene id: 90244:I6G29_RS07530
uniprot id: A0A378XHT7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

90244:I6G29 RS12320
gene id: 90244:I6G29_RS12320
uniprot id: A0A378XJZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

90244:I6G29 RS00400
gene id: 90244:I6G29_RS00400
uniprot id: A0A378X9F0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

90244:I6G29 RS09055
gene id: 90244:I6G29_RS09055
uniprot id: A0A378XHE1
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS07610
gene id: 90244:I6G29_RS07610
uniprot id: A0A378XFF9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

90244:I6G29 RS02640
gene id: 90244:I6G29_RS02640
uniprot id: A0A378XCJ7
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

90244:I6G29 RS00490
gene id: 90244:I6G29_RS00490
uniprot id: A0A378XCI2
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

90244:I6G29 RS05825
gene id: 90244:I6G29_RS05825
uniprot id: A0A378XFI6
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

90244:I6G29 RS01105
gene id: 90244:I6G29_RS01105
uniprot id: A0A378XAF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

90244:I6G29 RS05870
gene id: 90244:I6G29_RS05870
uniprot id: A0A378XFJ6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

90244:I6G29 RS02675
gene id: 90244:I6G29_RS02675
uniprot id: A0A378XEM7
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

90244:I6G29 RS06775
gene id: 90244:I6G29_RS06775
uniprot id: A0A378XGU8
names: Similarity
messages: Belongs to the catalase family.

90244:I6G29 RS04700
gene id: 90244:I6G29_RS04700
uniprot id: A0A378XER6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

90244:I6G29 RS03460
gene id: 90244:I6G29_RS03460
uniprot id: A0A378XCG1
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS01150
gene id: 90244:I6G29_RS01150
uniprot id: A0A378XCM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

90244:I6G29 RS13375
gene id: 90244:I6G29_RS13375
uniprot id: A0A378XB84
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

90244:I6G29 RS05475
gene id: 90244:I6G29_RS05475
uniprot id: A0A378XFC2
names: Subcellular Location Annotation
messages: target cell cytoplasm

90244:I6G29 RS06215
gene id: 90244:I6G29_RS06215
uniprot id: A0A378XE10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

90244:I6G29 RS00025
gene id: 90244:I6G29_RS00025
uniprot id: A0A379B157
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

90244:I6G29 RS12245
gene id: 90244:I6G29_RS12245
uniprot id: A0A378XI12
names: Similarity
messages: Belongs to the PhoH family.

90244:I6G29 RS03580
gene id: 90244:I6G29_RS03580
uniprot id: A0A378XFK7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

90244:I6G29 RS00960
gene id: 90244:I6G29_RS00960
uniprot id: A0A378XCE2
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

90244:I6G29 RS01675
gene id: 90244:I6G29_RS01675
uniprot id: A0A378XCC8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

90244:I6G29 RS08900
gene id: 90244:I6G29_RS08900
uniprot id: A0A378XHY5
names: Similarity
messages: Belongs to the DEAD box helicase family.

90244:I6G29 RS00430
gene id: 90244:I6G29_RS00430
uniprot id: A0A378X9W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

90244:I6G29 RS09425
gene id: 90244:I6G29_RS09425
uniprot id: A0A378XIE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

90244:I6G29 RS04750
gene id: 90244:I6G29_RS04750
uniprot id: A0A378XES8
names: Similarity
messages: Belongs to the serine/threonine dehydratase family. DsdA subfamily.

90244:I6G29 RS03835
gene id: 90244:I6G29_RS03835
uniprot id: A0A378XF87
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

90244:I6G29 RS05860
gene id: 90244:I6G29_RS05860
uniprot id: A0A378XGD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

90244:I6G29 RS04710
gene id: 90244:I6G29_RS04710
uniprot id: A0A378XFS1
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

90244:I6G29 RS04285
gene id: 90244:I6G29_RS04285
uniprot id: A0A378XCX7
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

90244:I6G29 RS05515
gene id: 90244:I6G29_RS05515
uniprot id: A0A378XG61
names: Similarity
messages: Belongs to the Nudix hydrolase family.

90244:I6G29 RS08555
gene id: 90244:I6G29_RS08555
uniprot id: A0A378XG21
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS05505
gene id: 90244:I6G29_RS05505
uniprot id: A0A378XGP9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

90244:I6G29 RS08175
gene id: 90244:I6G29_RS08175
uniprot id: A0A378XHJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

90244:I6G29 RS04790
gene id: 90244:I6G29_RS04790
uniprot id: A0A378XDU9
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS03935
gene id: 90244:I6G29_RS03935
uniprot id: A0A378XFA7
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

90244:I6G29 RS09800
gene id: 90244:I6G29_RS09800
uniprot id: A0A378XHV9
names: Similarity
messages: Belongs to the OsmC/Ohr family.

90244:I6G29 RS09355
gene id: 90244:I6G29_RS09355
uniprot id: A0A378XHJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

90244:I6G29 RS11065
gene id: 90244:I6G29_RS11065
uniprot id: A0A378XIC0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

90244:I6G29 RS05180
gene id: 90244:I6G29_RS05180
uniprot id: A0A378XF65
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

90244:I6G29 RS06600
gene id: 90244:I6G29_RS06600
uniprot id: A0A378XEG8
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

90244:I6G29 RS09475
gene id: 90244:I6G29_RS09475
uniprot id: A0A378XFT3
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS09970
gene id: 90244:I6G29_RS09970
uniprot id: A0A378XIK0
names: Function
names: Similarity
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.

90244:I6G29 RS13555
gene id: 90244:I6G29_RS13555
uniprot id: A0A378X962
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS05765
gene id: 90244:I6G29_RS05765
uniprot id: A0A378XGB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

90244:I6G29 RS05110
gene id: 90244:I6G29_RS05110
uniprot id: A0A378XGG4
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

90244:I6G29 RS07955
gene id: 90244:I6G29_RS07955
uniprot id: A0A378XGQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

90244:I6G29 RS02705
gene id: 90244:I6G29_RS02705
uniprot id: A0A378XDJ0
names: Similarity
messages: Belongs to the aspartokinase family.

90244:I6G29 RS04950
gene id: 90244:I6G29_RS04950
uniprot id: A0A378XDD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

90244:I6G29 RS00020
gene id: 90244:I6G29_RS00020
uniprot id: A0A379B0D7
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

90244:I6G29 RS02185
gene id: 90244:I6G29_RS02185
uniprot id: A0A378XE33
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

90244:I6G29 RS00680
gene id: 90244:I6G29_RS00680
uniprot id: A0A378XB13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

90244:I6G29 RS11115
gene id: 90244:I6G29_RS11115
uniprot id: A0A378XIC9
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

90244:I6G29 RS13175
gene id: 90244:I6G29_RS13175
uniprot id: A0A378XIK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

90244:I6G29 RS05265
gene id: 90244:I6G29_RS05265
uniprot id: A0A378XG32
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

90244:I6G29 RS09615
gene id: 90244:I6G29_RS09615
uniprot id: A0A378XFW2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

90244:I6G29 RS00355
gene id: 90244:I6G29_RS00355
uniprot id: A0A378X969
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

90244:I6G29 RS10450
gene id: 90244:I6G29_RS10450
uniprot id: A0A378XIY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

90244:I6G29 RS03250
gene id: 90244:I6G29_RS03250
uniprot id: A0A378XCZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

90244:I6G29 RS13480
gene id: 90244:I6G29_RS13480
uniprot id: A0A378XAM1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

90244:I6G29 RS07255
gene id: 90244:I6G29_RS07255
uniprot id: A0A378XEL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

90244:I6G29 RS02390
gene id: 90244:I6G29_RS02390
uniprot id: A0A378XE72
names: Similarity
messages: Belongs to the BolA/IbaG family.

90244:I6G29 RS03110
gene id: 90244:I6G29_RS03110
uniprot id: A0A378XDS9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

90244:I6G29 RS12415
gene id: 90244:I6G29_RS12415
uniprot id: A0A378XJ49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

90244:I6G29 RS07405
gene id: 90244:I6G29_RS07405
uniprot id: A0A378XFB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

90244:I6G29 RS08840
gene id: 90244:I6G29_RS08840
uniprot id: A0A378XI15
names: Similarity
messages: Belongs to the DprA/Smf family.

90244:I6G29 RS04450
gene id: 90244:I6G29_RS04450
uniprot id: A0A378XG27
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

90244:I6G29 RS09405
gene id: 90244:I6G29_RS09405
uniprot id: A0A378XHL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

90244:I6G29 RS03150
gene id: 90244:I6G29_RS03150
uniprot id: A0A378XC97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

90244:I6G29 RS05865
gene id: 90244:I6G29_RS05865
uniprot id: A0A378XE42
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS08325
gene id: 90244:I6G29_RS08325
uniprot id: A0A378XGT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

90244:I6G29 RS11810
gene id: 90244:I6G29_RS11810
uniprot id: A0A378XH56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

90244:I6G29 RS06505
gene id: 90244:I6G29_RS06505
uniprot id: A0A378XEW7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

90244:I6G29 RS10975
gene id: 90244:I6G29_RS10975
uniprot id: A0A378XJ76
names: Similarity
messages: Belongs to the UPF0751 family.

90244:I6G29 RS08360
gene id: 90244:I6G29_RS08360
uniprot id: A0A378XFW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

90244:I6G29 RS04495
gene id: 90244:I6G29_RS04495
uniprot id: A0A378XEL7
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

90244:I6G29 RS00805
gene id: 90244:I6G29_RS00805
uniprot id: A0A378XBF2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

90244:I6G29 RS08625
gene id: 90244:I6G29_RS08625
uniprot id: A0A378XH05
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

90244:I6G29 RS10440
gene id: 90244:I6G29_RS10440
uniprot id: A0A378XI05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

90244:I6G29 RS12985
gene id: 90244:I6G29_RS12985
uniprot id: A0A378XJF7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

90244:I6G29 RS12060
gene id: 90244:I6G29_RS12060
uniprot id: A0A378XKE6
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

90244:I6G29 RS02300
gene id: 90244:I6G29_RS02300
uniprot id: A0A378XDA4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS06835
gene id: 90244:I6G29_RS06835
uniprot id: A0A378XG26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

90244:I6G29 RS12915
gene id: 90244:I6G29_RS12915
uniprot id: A0A378XKC6
names: Similarity
messages: Belongs to the peptidase C40 family.

90244:I6G29 RS07835
gene id: 90244:I6G29_RS07835
uniprot id: A0A378XHZ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

90244:I6G29 RS09530
gene id: 90244:I6G29_RS09530
uniprot id: A0A378XHI9
names: Similarity
messages: Belongs to the transglycosylase Slt family.

90244:I6G29 RS12535
gene id: 90244:I6G29_RS12535
uniprot id: A0A378XJX9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS13290
gene id: 90244:I6G29_RS13290
uniprot id: A0A378X8N9
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

90244:I6G29 RS02040
gene id: 90244:I6G29_RS02040
uniprot id: A0A378XDU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane.
messages: Membrane

90244:I6G29 RS03560
gene id: 90244:I6G29_RS03560
uniprot id: A0A378XD26
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

90244:I6G29 RS12715
gene id: 90244:I6G29_RS12715
uniprot id: A0A378XK80
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

90244:I6G29 RS11265
gene id: 90244:I6G29_RS11265
uniprot id: A0A378XJE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

90244:I6G29 RS02965
gene id: 90244:I6G29_RS02965
uniprot id: A0A378XC59
names: Similarity
messages: Belongs to the ModE family.

90244:I6G29 RS11475
gene id: 90244:I6G29_RS11475
uniprot id: A0A378XJB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

90244:I6G29 RS00175
gene id: 90244:I6G29_RS00175
uniprot id: A0A379B186
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

90244:I6G29 RS12610
gene id: 90244:I6G29_RS12610
uniprot id: A0A378XHM1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

90244:I6G29 RS11960
gene id: 90244:I6G29_RS11960
uniprot id: A0A378XIV2
names: Similarity
messages: Belongs to the TrpF family.

90244:I6G29 RS11600
gene id: 90244:I6G29_RS11600
uniprot id: A0A378XHP3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

90244:I6G29 RS07915
gene id: 90244:I6G29_RS07915
uniprot id: A0A378XFL7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

90244:I6G29 RS12330
gene id: 90244:I6G29_RS12330
uniprot id: A0A378XHQ5
names: Similarity
messages: Belongs to the ArsC family.

90244:I6G29 RS08355
gene id: 90244:I6G29_RS08355
uniprot id: A0A378XFY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

90244:I6G29 RS07055
gene id: 90244:I6G29_RS07055
uniprot id: A0A378XG30
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

90244:I6G29 RS12460
gene id: 90244:I6G29_RS12460
uniprot id: A0A378XK37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

90244:I6G29 RS08480
gene id: 90244:I6G29_RS08480
uniprot id: A0A378XID0
names: Subcellular Location Annotation
messages: Periplasm

90244:I6G29 RS01210
gene id: 90244:I6G29_RS01210
uniprot id: A0A378XBZ0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

90244:I6G29 RS01255
gene id: 90244:I6G29_RS01255
uniprot id: A0A378XDD1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

90244:I6G29 RS03285
gene id: 90244:I6G29_RS03285
uniprot id: A0A378XEW3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS13170
gene id: 90244:I6G29_RS13170
uniprot id: A0A378XIN9
names: Similarity
messages: Belongs to the thioredoxin family.

90244:I6G29 RS11320
gene id: 90244:I6G29_RS11320
uniprot id: A0A378XK11
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

90244:I6G29 RS05790
gene id: 90244:I6G29_RS05790
uniprot id: A0A378XDT1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

90244:I6G29 RS05605
gene id: 90244:I6G29_RS05605
uniprot id: A0A378XGR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

90244:I6G29 RS01420
gene id: 90244:I6G29_RS01420
uniprot id: A0A378XCY6
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

90244:I6G29 RS11140
gene id: 90244:I6G29_RS11140
uniprot id: A0A378XIJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

90244:I6G29 RS07575
gene id: 90244:I6G29_RS07575
uniprot id: A0A378XGD1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

90244:I6G29 RS05815
gene id: 90244:I6G29_RS05815
uniprot id: A0A378XGC8
names: Similarity
messages: Belongs to the UPF0250 family.

90244:I6G29 RS01865
gene id: 90244:I6G29_RS01865
uniprot id: A0A378XB37
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

90244:I6G29 RS08490
gene id: 90244:I6G29_RS08490
uniprot id: A0A378XFI0
names: Similarity
messages: Belongs to the EfeM/EfeO family.

90244:I6G29 RS01030
gene id: 90244:I6G29_RS01030
uniprot id: A0A378XD48
names: Subcellular Location Annotation
messages: Cytoplasm

90244:I6G29 RS10430
gene id: 90244:I6G29_RS10430
uniprot id: A0A378XGB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

90244:I6G29 RS02200
gene id: 90244:I6G29_RS02200
uniprot id: A0A378XC30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

90244:I6G29 RS12745
gene id: 90244:I6G29_RS12745
uniprot id: A0A378XJF0
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

90244:I6G29 RS06100
gene id: 90244:I6G29_RS06100
uniprot id: A0A378XFP2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS13245
gene id: 90244:I6G29_RS13245
uniprot id: A0A378X980
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

90244:I6G29 RS01125
gene id: 90244:I6G29_RS01125
uniprot id: A0A378XCK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

90244:I6G29 RS08990
gene id: 90244:I6G29_RS08990
uniprot id: A0A378XI58
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

90244:I6G29 RS06590
gene id: 90244:I6G29_RS06590
uniprot id: A0A378XGQ8
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

90244:I6G29 RS07850
gene id: 90244:I6G29_RS07850
uniprot id: A0A378XF59
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

90244:I6G29 RS13115
gene id: 90244:I6G29_RS13115
uniprot id: A0A378XJL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

90244:I6G29 RS03015
gene id: 90244:I6G29_RS03015
uniprot id: A0A378XCU2
names: Similarity
messages: Belongs to the FMO family.

90244:I6G29 RS13445
gene id: 90244:I6G29_RS13445
uniprot id: A0A378XC08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

90244:I6G29 RS04575
gene id: 90244:I6G29_RS04575
uniprot id: A0A378XEU7
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS08345
gene id: 90244:I6G29_RS08345
uniprot id: A0A378XFF4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

90244:I6G29 RS06615
gene id: 90244:I6G29_RS06615
uniprot id: A0A378XEV1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

90244:I6G29 RS13310
gene id: 90244:I6G29_RS13310
uniprot id: A0A378X9A6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

90244:I6G29 RS09965
gene id: 90244:I6G29_RS09965
uniprot id: A0A378XIP4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NnrE/AIBP family.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS02680
gene id: 90244:I6G29_RS02680
uniprot id: A0A378XF22
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 104 family.
messages: Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes.

90244:I6G29 RS06495
gene id: 90244:I6G29_RS06495
uniprot id: A0A378XEE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

90244:I6G29 RS10190
gene id: 90244:I6G29_RS10190
uniprot id: A0A378XGX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

90244:I6G29 RS10840
gene id: 90244:I6G29_RS10840
uniprot id: A0A378XIE1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

90244:I6G29 RS00325
gene id: 90244:I6G29_RS00325
uniprot id: A0A378X9T0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS09630
gene id: 90244:I6G29_RS09630
uniprot id: A0A378XJ22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

90244:I6G29 RS06185
gene id: 90244:I6G29_RS06185
uniprot id: A0A378XGI7
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

90244:I6G29 RS06205
gene id: 90244:I6G29_RS06205
uniprot id: A0A378XEQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

90244:I6G29 RS10670
gene id: 90244:I6G29_RS10670
uniprot id: A0A378XJM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

90244:I6G29 RS05185
gene id: 90244:I6G29_RS05185
uniprot id: A0A378XE50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

90244:I6G29 RS00635
gene id: 90244:I6G29_RS00635
uniprot id: A0A378XCN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

90244:I6G29 RS11625
gene id: 90244:I6G29_RS11625
uniprot id: A0A378XJK4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

90244:I6G29 RS11645
gene id: 90244:I6G29_RS11645
uniprot id: A0A378XHU1
names: Function
names: Similarity
messages: Belongs to the ClpA/ClpB family.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

90244:I6G29 RS05500
gene id: 90244:I6G29_RS05500
uniprot id: A0A378XF74
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS00850
gene id: 90244:I6G29_RS00850
uniprot id: A0A378XB83
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS06025
gene id: 90244:I6G29_RS06025
uniprot id: A0A378XFH4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

90244:I6G29 RS06800
gene id: 90244:I6G29_RS06800
uniprot id: A0A378XEZ1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

90244:I6G29 RS07745
gene id: 90244:I6G29_RS07745
uniprot id: A0A378XGK9
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

90244:I6G29 RS00205
gene id: 90244:I6G29_RS00205
uniprot id: A0A379B0S2
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

90244:I6G29 RS06500
gene id: 90244:I6G29_RS06500
uniprot id: A0A378XFW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

90244:I6G29 RS09635
gene id: 90244:I6G29_RS09635
uniprot id: A0A378XII7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

90244:I6G29 RS00755
gene id: 90244:I6G29_RS00755
uniprot id: A0A378XBD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

90244:I6G29 RS02645
gene id: 90244:I6G29_RS02645
uniprot id: A0A378XCH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

90244:I6G29 RS05720
gene id: 90244:I6G29_RS05720
uniprot id: A0A378XE11
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

90244:I6G29 RS04275
gene id: 90244:I6G29_RS04275
uniprot id: A0A378XDI7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS05760
gene id: 90244:I6G29_RS05760
uniprot id: A0A378XGC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

90244:I6G29 RS12340
gene id: 90244:I6G29_RS12340
uniprot id: A0A378XI78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

90244:I6G29 RS13335
gene id: 90244:I6G29_RS13335
uniprot id: A0A378X9D8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

90244:I6G29 RS03260
gene id: 90244:I6G29_RS03260
uniprot id: A0A378XCC1
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

90244:I6G29 RS07840
gene id: 90244:I6G29_RS07840
uniprot id: A0A378XHG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

90244:I6G29 RS11415
gene id: 90244:I6G29_RS11415
uniprot id: A0A378XIJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

90244:I6G29 RS07905
gene id: 90244:I6G29_RS07905
uniprot id: A0A378XGN5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

90244:I6G29 RS06870
gene id: 90244:I6G29_RS06870
uniprot id: A0A378XGW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiV subfamily.
messages: Forms an heterodimer with UbiU.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

90244:I6G29 RS07595
gene id: 90244:I6G29_RS07595
uniprot id: A0A378XF14
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

90244:I6G29 RS01880
gene id: 90244:I6G29_RS01880
uniprot id: A0A378XBE9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

90244:I6G29 RS12390
gene id: 90244:I6G29_RS12390
uniprot id: A0A378XI88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

90244:I6G29 RS07090
gene id: 90244:I6G29_RS07090
uniprot id: A0A378XF53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

90244:I6G29 RS08295
gene id: 90244:I6G29_RS08295
uniprot id: A0A378XGW7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

90244:I6G29 RS09435
gene id: 90244:I6G29_RS09435
uniprot id: A0A378XIY0
names: Similarity
messages: Belongs to the peptidase S41A family.

90244:I6G29 RS08565
gene id: 90244:I6G29_RS08565
uniprot id: A0A378XFA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

90244:I6G29 RS01805
gene id: 90244:I6G29_RS01805
uniprot id: A0A378XB06
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS08740
gene id: 90244:I6G29_RS08740
uniprot id: A0A378XHZ2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

90244:I6G29 RS05960
gene id: 90244:I6G29_RS05960
uniprot id: A0A378XEI0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

90244:I6G29 RS04050
gene id: 90244:I6G29_RS04050
uniprot id: A0A378XD29
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

90244:I6G29 RS10845
gene id: 90244:I6G29_RS10845
uniprot id: A0A378XHE4
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

90244:I6G29 RS01160
gene id: 90244:I6G29_RS01160
uniprot id: A0A378XAQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

90244:I6G29 RS11390
gene id: 90244:I6G29_RS11390
uniprot id: A0A378XIP0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

90244:I6G29 RS07875
gene id: 90244:I6G29_RS07875
uniprot id: A0A378XHJ0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

90244:I6G29 RS03545
gene id: 90244:I6G29_RS03545
uniprot id: A0A378XCS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

90244:I6G29 RS09505
gene id: 90244:I6G29_RS09505
uniprot id: A0A378XHN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

90244:I6G29 RS08785
gene id: 90244:I6G29_RS08785
uniprot id: A0A378XIJ3
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

90244:I6G29 RS11975
gene id: 90244:I6G29_RS11975
uniprot id: A0A378XJL9
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

90244:I6G29 RS10195
gene id: 90244:I6G29_RS10195
uniprot id: A0A378XG80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

90244:I6G29 RS05255
gene id: 90244:I6G29_RS05255
uniprot id: A0A378XF24
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS00495
gene id: 90244:I6G29_RS00495
uniprot id: A0A378XBU1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

90244:I6G29 RS06715
gene id: 90244:I6G29_RS06715
uniprot id: A0A378XFW6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

90244:I6G29 RS03385
gene id: 90244:I6G29_RS03385
uniprot id: A0A378XEY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

90244:I6G29 RS06075
gene id: 90244:I6G29_RS06075
uniprot id: A0A378XFI4
names: Similarity
messages: Belongs to the DEAD box helicase family.

90244:I6G29 RS11660
gene id: 90244:I6G29_RS11660
uniprot id: A0A378XJM7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

90244:I6G29 RS07015
gene id: 90244:I6G29_RS07015
uniprot id: A0A378XGZ7
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

90244:I6G29 RS08340
gene id: 90244:I6G29_RS08340
uniprot id: A0A378XHM4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

90244:I6G29 RS00345
gene id: 90244:I6G29_RS00345
uniprot id: A0A378X9E0
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS08550
gene id: 90244:I6G29_RS08550
uniprot id: A0A378XH17
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS05570
gene id: 90244:I6G29_RS05570
uniprot id: A0A378XDY1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS06035
gene id: 90244:I6G29_RS06035
uniprot id: A0A378XGF8
names: Similarity
messages: Belongs to the BolA/IbaG family.

90244:I6G29 RS09710
gene id: 90244:I6G29_RS09710
uniprot id: A0A378XGN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

90244:I6G29 RS10490
gene id: 90244:I6G29_RS10490
uniprot id: A0A378XI13
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

90244:I6G29 RS12160
gene id: 90244:I6G29_RS12160
uniprot id: A0A378XIZ5
names: Similarity
messages: Belongs to the leucine-binding protein family.

90244:I6G29 RS08365
gene id: 90244:I6G29_RS08365
uniprot id: A0A378XF61
names: Similarity
messages: Belongs to the ABC transporter superfamily.

90244:I6G29 RS09845
gene id: 90244:I6G29_RS09845
uniprot id: A0A378XIH6
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

90244:I6G29 RS11435
gene id: 90244:I6G29_RS11435
uniprot id: A0A378XH79
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

90244:I6G29 RS05540
gene id: 90244:I6G29_RS05540
uniprot id: A0A378XDN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

90244:I6G29 RS05495
gene id: 90244:I6G29_RS05495
uniprot id: A0A378XG90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

90244:I6G29 RS04035
gene id: 90244:I6G29_RS04035
uniprot id: A0A378XFU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

90244:I6G29 RS11130
gene id: 90244:I6G29_RS11130
uniprot id: A0A378XJ53
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

90244:I6G29 RS03730
gene id: 90244:I6G29_RS03730
uniprot id: A0A378XFN6
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

90244:I6G29 RS01940
gene id: 90244:I6G29_RS01940
uniprot id: A0A378XBT5
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS13465
gene id: 90244:I6G29_RS13465
uniprot id: A0A378XBI0
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

90244:I6G29 RS00725
gene id: 90244:I6G29_RS00725
uniprot id: A0A378XCS9
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

90244:I6G29 RS12270
gene id: 90244:I6G29_RS12270
uniprot id: A0A378XJY6
names: Similarity
messages: Belongs to the threonine synthase family.

90244:I6G29 RS06995
gene id: 90244:I6G29_RS06995
uniprot id: A0A378XEF9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

90244:I6G29 RS06795
gene id: 90244:I6G29_RS06795
uniprot id: A0A378XF19
names: Function
names: Similarity
messages: Belongs to the histone H1/H5 family. HCT subfamily.
messages: Belongs to the type IA topoisomerase family.
messages: Might have a role in establishing the nucleoid structure of elementary bodies.

90244:I6G29 RS08845
gene id: 90244:I6G29_RS08845
uniprot id: A0A378XHX6
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

90244:I6G29 RS11060
gene id: 90244:I6G29_RS11060
uniprot id: A0A378XJA5
names: Similarity
messages: Belongs to the UPF0758 family.

90244:I6G29 RS01405
gene id: 90244:I6G29_RS01405
uniprot id: A0A378XB16
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

90244:I6G29 RS12355
gene id: 90244:I6G29_RS12355
uniprot id: A0A378XK20
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS10235
gene id: 90244:I6G29_RS10235
uniprot id: A0A378XH34
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

90244:I6G29 RS00460
gene id: 90244:I6G29_RS00460
uniprot id: A0A378XBZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

90244:I6G29 RS11005
gene id: 90244:I6G29_RS11005
uniprot id: A0A378XGM8
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

90244:I6G29 RS06020
gene id: 90244:I6G29_RS06020
uniprot id: A0A378XGJ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

90244:I6G29 RS00290
gene id: 90244:I6G29_RS00290
uniprot id: A0A378XBL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

90244:I6G29 RS07815
gene id: 90244:I6G29_RS07815
uniprot id: A0A378XFK0
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

90244:I6G29 RS11895
gene id: 90244:I6G29_RS11895
uniprot id: A0A378XHY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

90244:I6G29 RS09650
gene id: 90244:I6G29_RS09650
uniprot id: A0A378XHS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

90244:I6G29 RS05270
gene id: 90244:I6G29_RS05270
uniprot id: A0A378XG15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

90244:I6G29 RS09045
gene id: 90244:I6G29_RS09045
uniprot id: A0A378XI19
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

90244:I6G29 RS09165
gene id: 90244:I6G29_RS09165
uniprot id: A0A378XFM4
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

90244:I6G29 RS12665
gene id: 90244:I6G29_RS12665
uniprot id: A0A378XK70
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS11290
gene id: 90244:I6G29_RS11290
uniprot id: A0A378XIM1
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS05285
gene id: 90244:I6G29_RS05285
uniprot id: A0A378XE68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

90244:I6G29 RS03380
gene id: 90244:I6G29_RS03380
uniprot id: A0A378XEZ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

90244:I6G29 RS07830
gene id: 90244:I6G29_RS07830
uniprot id: A0A378XGH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

90244:I6G29 RS00840
gene id: 90244:I6G29_RS00840
uniprot id: A0A378XBG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

90244:I6G29 RS10225
gene id: 90244:I6G29_RS10225
uniprot id: A0A378XGJ3
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

90244:I6G29 RS11540
gene id: 90244:I6G29_RS11540
uniprot id: A0A378XHS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

90244:I6G29 RS07080
gene id: 90244:I6G29_RS07080
uniprot id: A0A378XG75
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

90244:I6G29 RS10765
gene id: 90244:I6G29_RS10765
uniprot id: A0A378XI66
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

90244:I6G29 RS04080
gene id: 90244:I6G29_RS04080
uniprot id: A0A378XED2
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS11275
gene id: 90244:I6G29_RS11275
uniprot id: A0A378XJD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NosZ family.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.
messages: Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide.
messages: Periplasm

90244:I6G29 RS03910
gene id: 90244:I6G29_RS03910
uniprot id: A0A378XDC1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

90244:I6G29 RS13380
gene id: 90244:I6G29_RS13380
uniprot id: A0A378XAI1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

90244:I6G29 RS04265
gene id: 90244:I6G29_RS04265
uniprot id: A0A378XD85
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

90244:I6G29 RS13365
gene id: 90244:I6G29_RS13365
uniprot id: A0A378XBE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

90244:I6G29 RS07910
gene id: 90244:I6G29_RS07910
uniprot id: A0A378XFP3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

90244:I6G29 RS10625
gene id: 90244:I6G29_RS10625
uniprot id: A0A378XJ13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

90244:I6G29 RS12455
gene id: 90244:I6G29_RS12455
uniprot id: A0A378XHI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

90244:I6G29 RS10150
gene id: 90244:I6G29_RS10150
uniprot id: A0A378XIT4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS08775
gene id: 90244:I6G29_RS08775
uniprot id: A0A378XI14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

90244:I6G29 RS08750
gene id: 90244:I6G29_RS08750
uniprot id: A0A378XFN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

90244:I6G29 RS09000
gene id: 90244:I6G29_RS09000
uniprot id: A0A378XFT6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

90244:I6G29 RS04395
gene id: 90244:I6G29_RS04395
uniprot id: A0A378XEJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

90244:I6G29 RS02955
gene id: 90244:I6G29_RS02955
uniprot id: A0A378XCQ9
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS04480
gene id: 90244:I6G29_RS04480
uniprot id: A0A378XDN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

90244:I6G29 RS11095
gene id: 90244:I6G29_RS11095
uniprot id: A0A378XHJ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

90244:I6G29 RS04550
gene id: 90244:I6G29_RS04550
uniprot id: A0A378XFQ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

90244:I6G29 RS12695
gene id: 90244:I6G29_RS12695
uniprot id: A0A378XJD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

90244:I6G29 RS02360
gene id: 90244:I6G29_RS02360
uniprot id: A0A378XER2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

90244:I6G29 RS04560
gene id: 90244:I6G29_RS04560
uniprot id: A0A378XG47
names: Similarity
messages: Belongs to the phosphohexose mutase family.

90244:I6G29 RS11715
gene id: 90244:I6G29_RS11715
uniprot id: A0A378XIQ1
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

90244:I6G29 RS03930
gene id: 90244:I6G29_RS03930
uniprot id: A0A378XFS5
names: Similarity
messages: Belongs to the barstar family.

90244:I6G29 RS05145
gene id: 90244:I6G29_RS05145
uniprot id: A0A378XDG6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

90244:I6G29 RS01520
gene id: 90244:I6G29_RS01520
uniprot id: A0A378XDR3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

90244:I6G29 RS05945
gene id: 90244:I6G29_RS05945
uniprot id: A0A378XE52
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

90244:I6G29 RS06895
gene id: 90244:I6G29_RS06895
uniprot id: A0A378XED9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

90244:I6G29 RS05875
gene id: 90244:I6G29_RS05875
uniprot id: A0A378XEJ2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

90244:I6G29 RS06580
gene id: 90244:I6G29_RS06580
uniprot id: A0A378XFT8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

90244:I6G29 RS10420
gene id: 90244:I6G29_RS10420
uniprot id: A0A378XH64
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

90244:I6G29 RS09955
gene id: 90244:I6G29_RS09955
uniprot id: A0A378XHS6
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

90244:I6G29 RS04590
gene id: 90244:I6G29_RS04590
uniprot id: A0A378XD54
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS10015
gene id: 90244:I6G29_RS10015
uniprot id: A0A378XIQ4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

90244:I6G29 RS06030
gene id: 90244:I6G29_RS06030
uniprot id: A0A378XH02
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS05175
gene id: 90244:I6G29_RS05175
uniprot id: A0A378XDR5
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

90244:I6G29 RS02215
gene id: 90244:I6G29_RS02215
uniprot id: A0A378XEK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

90244:I6G29 RS13345
gene id: 90244:I6G29_RS13345
uniprot id: A0A378XA55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

90244:I6G29 RS01270
gene id: 90244:I6G29_RS01270
uniprot id: A0A378XAV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

90244:I6G29 RS00555
gene id: 90244:I6G29_RS00555
uniprot id: A0A378X9F7
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

90244:I6G29 RS10000
gene id: 90244:I6G29_RS10000
uniprot id: A0A378XIQ3
names: Similarity
messages: Belongs to the pirin family.

90244:I6G29 RS06455
gene id: 90244:I6G29_RS06455
uniprot id: A0A378XEV4
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS02375
gene id: 90244:I6G29_RS02375
uniprot id: A0A378XCA2
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS00625
gene id: 90244:I6G29_RS00625
uniprot id: A0A378XA41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

90244:I6G29 RS10655
gene id: 90244:I6G29_RS10655
uniprot id: A0A378XGG2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

90244:I6G29 RS07345
gene id: 90244:I6G29_RS07345
uniprot id: A0A378XGC7
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

90244:I6G29 RS05240
gene id: 90244:I6G29_RS05240
uniprot id: A0A378XE45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

90244:I6G29 RS11515
gene id: 90244:I6G29_RS11515
uniprot id: A0A378XK46
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS06430
gene id: 90244:I6G29_RS06430
uniprot id: A0A378XH70
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

90244:I6G29 RS11800
gene id: 90244:I6G29_RS11800
uniprot id: A0A378XHW8
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

90244:I6G29 RS10520
gene id: 90244:I6G29_RS10520
uniprot id: A0A378XH83
names: Similarity
messages: Belongs to the class-I fumarase family.

90244:I6G29 RS03405
gene id: 90244:I6G29_RS03405
uniprot id: A0A378XCZ7
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

90244:I6G29 RS05680
gene id: 90244:I6G29_RS05680
uniprot id: A0A378XEF0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

90244:I6G29 RS05195
gene id: 90244:I6G29_RS05195
uniprot id: A0A378XDH6
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

90244:I6G29 RS00510
gene id: 90244:I6G29_RS00510
uniprot id: A0A378XC17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

90244:I6G29 RS11045
gene id: 90244:I6G29_RS11045
uniprot id: A0A378XHI2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family.
messages: Part of the 50S ribosomal subunit.

90244:I6G29 RS09025
gene id: 90244:I6G29_RS09025
uniprot id: A0A378XI64
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

90244:I6G29 RS09500
gene id: 90244:I6G29_RS09500
uniprot id: A0A378XG46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

90244:I6G29 RS13015
gene id: 90244:I6G29_RS13015
uniprot id: A0A378XIL0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

90244:I6G29 RS08915
gene id: 90244:I6G29_RS08915
uniprot id: A0A378XG74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

90244:I6G29 RS10180
gene id: 90244:I6G29_RS10180
uniprot id: A0A378XI30
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

90244:I6G29 RS07385
gene id: 90244:I6G29_RS07385
uniprot id: A0A378XH54
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

90244:I6G29 RS00260
gene id: 90244:I6G29_RS00260
uniprot id: A0A378XBM9
names: Similarity
messages: Belongs to the YicC/YloC family.

90244:I6G29 RS06785
gene id: 90244:I6G29_RS06785
uniprot id: A0A378XEK3
names: Similarity
messages: Belongs to the Smg family.

90244:I6G29 RS07200
gene id: 90244:I6G29_RS07200
uniprot id: A0A378XFA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

90244:I6G29 RS00790
gene id: 90244:I6G29_RS00790
uniprot id: A0A378XCE4
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS09565
gene id: 90244:I6G29_RS09565
uniprot id: A0A378XFV2
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS05995
gene id: 90244:I6G29_RS05995
uniprot id: A0A378XE61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

90244:I6G29 RS12425
gene id: 90244:I6G29_RS12425
uniprot id: A0A378XK16
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

90244:I6G29 RS07000
gene id: 90244:I6G29_RS07000
uniprot id: A0A378XH22
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.

90244:I6G29 RS06085
gene id: 90244:I6G29_RS06085
uniprot id: A0A378XGG6
names: Similarity
messages: Belongs to the SCO1/2 family.

90244:I6G29 RS07730
gene id: 90244:I6G29_RS07730
uniprot id: A0A378XHE3
names: Similarity
messages: Belongs to the HSP15 family.

90244:I6G29 RS09320
gene id: 90244:I6G29_RS09320
uniprot id: A0A378XFQ5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

90244:I6G29 RS06270
gene id: 90244:I6G29_RS06270
uniprot id: A0A378XGQ4
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS04760
gene id: 90244:I6G29_RS04760
uniprot id: A0A378XFT0
names: Similarity
messages: Belongs to the universal stress protein A family.

90244:I6G29 RS13360
gene id: 90244:I6G29_RS13360
uniprot id: A0A378X9E6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

90244:I6G29 RS01265
gene id: 90244:I6G29_RS01265
uniprot id: A0A378XC13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

90244:I6G29 RS00280
gene id: 90244:I6G29_RS00280
uniprot id: A0A378XC96
names: Similarity
messages: Belongs to the glutamine synthetase family.

90244:I6G29 RS09560
gene id: 90244:I6G29_RS09560
uniprot id: A0A378XGL0
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

90244:I6G29 RS11480
gene id: 90244:I6G29_RS11480
uniprot id: A0A378XH89
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

90244:I6G29 RS09595
gene id: 90244:I6G29_RS09595
uniprot id: A0A378XG68
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

90244:I6G29 RS04655
gene id: 90244:I6G29_RS04655
uniprot id: A0A378XG77
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

90244:I6G29 RS08720
gene id: 90244:I6G29_RS08720
uniprot id: A0A378XFD8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

90244:I6G29 RS03520
gene id: 90244:I6G29_RS03520
uniprot id: A0A378XF68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

90244:I6G29 RS13500
gene id: 90244:I6G29_RS13500
uniprot id: A0A378XC27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

90244:I6G29 RS11225
gene id: 90244:I6G29_RS11225
uniprot id: A0A378XJZ1
names: Function
names: Similarity
messages: Belongs to the PhnJ family.
messages: Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose.

90244:I6G29 RS12690
gene id: 90244:I6G29_RS12690
uniprot id: A0A378XHX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

90244:I6G29 RS05545
gene id: 90244:I6G29_RS05545
uniprot id: A0A378XG99
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

90244:I6G29 RS07005
gene id: 90244:I6G29_RS07005
uniprot id: A0A378XG20
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

90244:I6G29 RS04350
gene id: 90244:I6G29_RS04350
uniprot id: A0A378XG07
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

90244:I6G29 RS00265
gene id: 90244:I6G29_RS00265
uniprot id: A0A378X996
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

90244:I6G29 RS05155
gene id: 90244:I6G29_RS05155
uniprot id: A0A378XF03
names: Similarity
messages: Belongs to the YggT family.

90244:I6G29 RS06935
gene id: 90244:I6G29_RS06935
uniprot id: A0A378XF60
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

90244:I6G29 RS08275
gene id: 90244:I6G29_RS08275
uniprot id: A0A378XI83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

90244:I6G29 RS09410
gene id: 90244:I6G29_RS09410
uniprot id: A0A378XGK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

90244:I6G29 RS13370
gene id: 90244:I6G29_RS13370
uniprot id: A0A378XBY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

90244:I6G29 RS10155
gene id: 90244:I6G29_RS10155
uniprot id: A0A378XHW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

90244:I6G29 RS01155
gene id: 90244:I6G29_RS01155
uniprot id: A0A378XBW7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

90244:I6G29 RS13435
gene id: 90244:I6G29_RS13435
uniprot id: A0A378X9G3
names: Similarity
messages: Belongs to the RecJ family.

90244:I6G29 RS03755
gene id: 90244:I6G29_RS03755
uniprot id: A0A378XD76
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

90244:I6G29 RS12530
gene id: 90244:I6G29_RS12530
uniprot id: A0A378XK36
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

90244:I6G29 RS04935
gene id: 90244:I6G29_RS04935
uniprot id: A0A378XF27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

90244:I6G29 RS07540
gene id: 90244:I6G29_RS07540
uniprot id: A0A378XH77
names: Similarity
messages: Belongs to the UPF0178 family.

90244:I6G29 RS05990
gene id: 90244:I6G29_RS05990
uniprot id: A0A378XGF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

90244:I6G29 RS10635
gene id: 90244:I6G29_RS10635
uniprot id: A0A378XGQ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

90244:I6G29 RS11120
gene id: 90244:I6G29_RS11120
uniprot id: A0A378XJW6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

90244:I6G29 RS13395
gene id: 90244:I6G29_RS13395
uniprot id: A0A378XBB7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

90244:I6G29 RS11315
gene id: 90244:I6G29_RS11315
uniprot id: A0A378XIH4
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

90244:I6G29 RS09680
gene id: 90244:I6G29_RS09680
uniprot id: A0A378XJ32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

90244:I6G29 RS03765
gene id: 90244:I6G29_RS03765
uniprot id: A0A378XCM5
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

90244:I6G29 RS05655
gene id: 90244:I6G29_RS05655
uniprot id: A0A378XGS8
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

90244:I6G29 RS09290
gene id: 90244:I6G29_RS09290
uniprot id: A0A378XIA9
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

90244:I6G29 RS06905
gene id: 90244:I6G29_RS06905
uniprot id: A0A378XG05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

90244:I6G29 RS00765
gene id: 90244:I6G29_RS00765
uniprot id: A0A378XCD4
names: Similarity
messages: Belongs to the SCO1/2 family.

90244:I6G29 RS11920
gene id: 90244:I6G29_RS11920
uniprot id: A0A378XKC1
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS05785
gene id: 90244:I6G29_RS05785
uniprot id: A0A378XEF1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

90244:I6G29 RS00640
gene id: 90244:I6G29_RS00640
uniprot id: A0A378XC26
names: Similarity
messages: Belongs to the Skp family.

90244:I6G29 RS05805
gene id: 90244:I6G29_RS05805
uniprot id: A0A378XGW0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

90244:I6G29 RS11820
gene id: 90244:I6G29_RS11820
uniprot id: A0A378XIS1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

90244:I6G29 RS11370
gene id: 90244:I6G29_RS11370
uniprot id: A0A378XK21
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

90244:I6G29 RS05810
gene id: 90244:I6G29_RS05810
uniprot id: A0A378XGC4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

90244:I6G29 RS06720
gene id: 90244:I6G29_RS06720
uniprot id: A0A378XHC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

90244:I6G29 RS02650
gene id: 90244:I6G29_RS02650
uniprot id: A0A378XEL9
names: Similarity
messages: Belongs to the citrate synthase family.

90244:I6G29 RS09385
gene id: 90244:I6G29_RS09385
uniprot id: A0A378XIX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

90244:I6G29 RS00405
gene id: 90244:I6G29_RS00405
uniprot id: A0A378X9V8
names: Similarity
messages: Belongs to the RutC family.

90244:I6G29 RS06130
gene id: 90244:I6G29_RS06130
uniprot id: A0A378XH10
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

90244:I6G29 RS11945
gene id: 90244:I6G29_RS11945
uniprot id: A0A378XHW1
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

90244:I6G29 RS07985
gene id: 90244:I6G29_RS07985
uniprot id: A0A378XI27
names: Similarity
messages: Belongs to the type III secretion exporter family.

90244:I6G29 RS05090
gene id: 90244:I6G29_RS05090
uniprot id: A0A378XE18
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters.

90244:I6G29 RS11350
gene id: 90244:I6G29_RS11350
uniprot id: A0A378XHJ1
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS00270
gene id: 90244:I6G29_RS00270
uniprot id: A0A378X9Q8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

90244:I6G29 RS02665
gene id: 90244:I6G29_RS02665
uniprot id: A0A378XDP6
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

90244:I6G29 RS13270
gene id: 90244:I6G29_RS13270
uniprot id: A0A378XA23
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

90244:I6G29 RS11135
gene id: 90244:I6G29_RS11135
uniprot id: A0A378XH12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

90244:I6G29 RS04435
gene id: 90244:I6G29_RS04435
uniprot id: A0A378XD09
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

90244:I6G29 RS02405
gene id: 90244:I6G29_RS02405
uniprot id: A0A378XC84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.

90244:I6G29 RS06365
gene id: 90244:I6G29_RS06365
uniprot id: A0A378XBF4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

90244:I6G29 RS11590
gene id: 90244:I6G29_RS11590
uniprot id: A0A378XIS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

90244:I6G29 RS06825
gene id: 90244:I6G29_RS06825
uniprot id: A0A378XGV4
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS03815
gene id: 90244:I6G29_RS03815
uniprot id: A0A378XCN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

90244:I6G29 RS08975
gene id: 90244:I6G29_RS08975
uniprot id: A0A378XI56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

90244:I6G29 RS01280
gene id: 90244:I6G29_RS01280
uniprot id: A0A378XCV5
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

90244:I6G29 RS03305
gene id: 90244:I6G29_RS03305
uniprot id: A0A378XCX2
names: Similarity
messages: Belongs to the peptidase M1 family.

90244:I6G29 RS07085
gene id: 90244:I6G29_RS07085
uniprot id: A0A378XF86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

90244:I6G29 RS12735
gene id: 90244:I6G29_RS12735
uniprot id: A0A378XK17
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

90244:I6G29 RS08180
gene id: 90244:I6G29_RS08180
uniprot id: A0A378XFC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

90244:I6G29 RS02455
gene id: 90244:I6G29_RS02455
uniprot id: A0A378XBR5
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

90244:I6G29 RS09580
gene id: 90244:I6G29_RS09580
uniprot id: A0A378XJ09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

90244:I6G29 RS12885
gene id: 90244:I6G29_RS12885
uniprot id: A0A378XK51
names: Similarity
messages: Belongs to the plasmid replication initiation factor family.

90244:I6G29 RS06630
gene id: 90244:I6G29_RS06630
uniprot id: A0A378XFU7
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS09200
gene id: 90244:I6G29_RS09200
uniprot id: A0A378XGG1
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

90244:I6G29 RS04840
gene id: 90244:I6G29_RS04840
uniprot id: A0A378XDW4
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS03925
gene id: 90244:I6G29_RS03925
uniprot id: A0A378XE96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

90244:I6G29 RS04040
gene id: 90244:I6G29_RS04040
uniprot id: A0A378XFC3
names: Similarity
messages: Belongs to the UreD family.

90244:I6G29 RS13260
gene id: 90244:I6G29_RS13260
uniprot id: A0A378X9A7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

90244:I6G29 RS06875
gene id: 90244:I6G29_RS06875
uniprot id: A0A378XGW5
names: Function
names: Similarity
messages: Belongs to the UbiT family.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor.

90244:I6G29 RS03565
gene id: 90244:I6G29_RS03565
uniprot id: A0A378XCI1
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

90244:I6G29 RS06335
gene id: 90244:I6G29_RS06335
uniprot id: A0A378XBF4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

90244:I6G29 RS12790
gene id: 90244:I6G29_RS12790
uniprot id: A0A378XI00
names: Similarity
messages: Belongs to the peptidase S24 family.

90244:I6G29 RS08860
gene id: 90244:I6G29_RS08860
uniprot id: A0A378XG81
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS03165
gene id: 90244:I6G29_RS03165
uniprot id: A0A378XFD5
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

90244:I6G29 RS09300
gene id: 90244:I6G29_RS09300
uniprot id: A0A378XFZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

90244:I6G29 RS03415
gene id: 90244:I6G29_RS03415
uniprot id: A0A378XF42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

90244:I6G29 RS06355
gene id: 90244:I6G29_RS06355
uniprot id: A0A378XGL3
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

90244:I6G29 RS03475
gene id: 90244:I6G29_RS03475
uniprot id: A0A378XFI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

90244:I6G29 RS06685
gene id: 90244:I6G29_RS06685
uniprot id: A0A378XEI7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

90244:I6G29 RS08110
gene id: 90244:I6G29_RS08110
uniprot id: A0A378XHN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

90244:I6G29 RS11735
gene id: 90244:I6G29_RS11735
uniprot id: A0A378XHE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

90244:I6G29 RS11550
gene id: 90244:I6G29_RS11550
uniprot id: A0A378XGZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

90244:I6G29 RS00480
gene id: 90244:I6G29_RS00480
uniprot id: A0A378X9Z1
names: Similarity
messages: Belongs to the GST superfamily.

90244:I6G29 RS05115
gene id: 90244:I6G29_RS05115
uniprot id: A0A378XG00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

90244:I6G29 RS06150
gene id: 90244:I6G29_RS06150
uniprot id: A0A378XFP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

90244:I6G29 RS10480
gene id: 90244:I6G29_RS10480
uniprot id: A0A378XGC5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

90244:I6G29 RS08430
gene id: 90244:I6G29_RS08430
uniprot id: A0A378XIB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

90244:I6G29 RS05060
gene id: 90244:I6G29_RS05060
uniprot id: A0A378XGF6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

90244:I6G29 RS00015
gene id: 90244:I6G29_RS00015
uniprot id: A0A379B0D1
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS06230
gene id: 90244:I6G29_RS06230
uniprot id: A0A378XH27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Periplasm

90244:I6G29 RS04845
gene id: 90244:I6G29_RS04845
uniprot id: A0A378XDA5
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

90244:I6G29 RS11890
gene id: 90244:I6G29_RS11890
uniprot id: A0A378XIY8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

90244:I6G29 RS04630
gene id: 90244:I6G29_RS04630
uniprot id: A0A378XDS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

90244:I6G29 RS00310
gene id: 90244:I6G29_RS00310
uniprot id: A0A378XCA7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS10085
gene id: 90244:I6G29_RS10085
uniprot id: A0A378XGW1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

90244:I6G29 RS00605
gene id: 90244:I6G29_RS00605
uniprot id: A0A378XAX7
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

90244:I6G29 RS00585
gene id: 90244:I6G29_RS00585
uniprot id: A0A378XCL8
names: Similarity
messages: Belongs to the band 7/mec-2 family.

90244:I6G29 RS03340
gene id: 90244:I6G29_RS03340
uniprot id: A0A378XCN7
names: Similarity
messages: Belongs to the GARS family.

90244:I6G29 RS02975
gene id: 90244:I6G29_RS02975
uniprot id: A0A378XDQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

90244:I6G29 RS10810
gene id: 90244:I6G29_RS10810
uniprot id: A0A378XJ55
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

90244:I6G29 RS09855
gene id: 90244:I6G29_RS09855
uniprot id: A0A378XHX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

90244:I6G29 RS12310
gene id: 90244:I6G29_RS12310
uniprot id: A0A378XJ27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

90244:I6G29 RS00855
gene id: 90244:I6G29_RS00855
uniprot id: A0A378XCB8
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS06690
gene id: 90244:I6G29_RS06690
uniprot id: A0A378XFZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

90244:I6G29 RS00330
gene id: 90244:I6G29_RS00330
uniprot id: A0A378X958
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

90244:I6G29 RS06700
gene id: 90244:I6G29_RS06700
uniprot id: A0A378XEX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

90244:I6G29 RS04585
gene id: 90244:I6G29_RS04585
uniprot id: A0A378XDQ5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

90244:I6G29 RS04535
gene id: 90244:I6G29_RS04535
uniprot id: A0A378XDP8
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

90244:I6G29 RS10005
gene id: 90244:I6G29_RS10005
uniprot id: A0A378XHT8
names: Similarity
messages: Belongs to the peptidase S49 family.

90244:I6G29 RS13505
gene id: 90244:I6G29_RS13505
uniprot id: A0A378XBD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

90244:I6G29 RS12420
gene id: 90244:I6G29_RS12420
uniprot id: A0A378XKL8
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

90244:I6G29 RS08260
gene id: 90244:I6G29_RS08260
uniprot id: A0A378XF41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

90244:I6G29 RS07695
gene id: 90244:I6G29_RS07695
uniprot id: A0A378XF30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

90244:I6G29 RS08685
gene id: 90244:I6G29_RS08685
uniprot id: A0A378XIH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

90244:I6G29 RS09160
gene id: 90244:I6G29_RS09160
uniprot id: A0A378XGE7
names: Similarity
messages: Belongs to the ArsC family.

90244:I6G29 RS03915
gene id: 90244:I6G29_RS03915
uniprot id: A0A378XCQ4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

90244:I6G29 RS01025
gene id: 90244:I6G29_RS01025
uniprot id: A0A378XCP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

90244:I6G29 RS08305
gene id: 90244:I6G29_RS08305
uniprot id: A0A378XFV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

90244:I6G29 RS10140
gene id: 90244:I6G29_RS10140
uniprot id: A0A378XGW9
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS13105
gene id: 90244:I6G29_RS13105
uniprot id: A0A378XK94
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

90244:I6G29 RS10425
gene id: 90244:I6G29_RS10425
uniprot id: A0A378XH18
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

90244:I6G29 RS02620
gene id: 90244:I6G29_RS02620
uniprot id: A0A378XBY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

90244:I6G29 RS03410
gene id: 90244:I6G29_RS03410
uniprot id: A0A378XCE9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS13870
gene id: 90244:I6G29_RS13870
uniprot id: A0A378XHR9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

90244:I6G29 RS06200
gene id: 90244:I6G29_RS06200
uniprot id: A0A378XFR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

90244:I6G29 RS03760
gene id: 90244:I6G29_RS03760
uniprot id: A0A378XD88
names: Subcellular Location Annotation
messages: Cytoplasm

90244:I6G29 RS13340
gene id: 90244:I6G29_RS13340
uniprot id: A0A378X8R0
names: Similarity
messages: Belongs to the YfgM family.

90244:I6G29 RS09590
gene id: 90244:I6G29_RS09590
uniprot id: A0A378XIC2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

90244:I6G29 RS04360
gene id: 90244:I6G29_RS04360
uniprot id: A0A378XFI3
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

90244:I6G29 RS03645
gene id: 90244:I6G29_RS03645
uniprot id: A0A378XCU8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

90244:I6G29 RS03265
gene id: 90244:I6G29_RS03265
uniprot id: A0A378XF10
names: Similarity
messages: Belongs to the SAICAR synthetase family.

90244:I6G29 RS11865
gene id: 90244:I6G29_RS11865
uniprot id: A0A378XJR7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

90244:I6G29 RS00620
gene id: 90244:I6G29_RS00620
uniprot id: A0A378XA48
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

90244:I6G29 RS05730
gene id: 90244:I6G29_RS05730
uniprot id: A0A378XEG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

90244:I6G29 RS01810
gene id: 90244:I6G29_RS01810
uniprot id: A0A378XCJ2
names: Similarity
messages: Belongs to the leucine-binding protein family.

90244:I6G29 RS11885
gene id: 90244:I6G29_RS11885
uniprot id: A0A378XHH4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

90244:I6G29 RS04855
gene id: 90244:I6G29_RS04855
uniprot id: A0A378XEU5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

90244:I6G29 RS04540
gene id: 90244:I6G29_RS04540
uniprot id: A0A378XDP4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.

90244:I6G29 RS09315
gene id: 90244:I6G29_RS09315
uniprot id: A0A378XGF5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

90244:I6G29 RS12300
gene id: 90244:I6G29_RS12300
uniprot id: A0A378XHG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

90244:I6G29 RS13510
gene id: 90244:I6G29_RS13510
uniprot id: A0A378X9J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

90244:I6G29 RS10330
gene id: 90244:I6G29_RS10330
uniprot id: A0A378XGL4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

90244:I6G29 RS01505
gene id: 90244:I6G29_RS01505
uniprot id: A0A378XCC3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

90244:I6G29 RS06460
gene id: 90244:I6G29_RS06460
uniprot id: A0A378XES0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

90244:I6G29 RS04060
gene id: 90244:I6G29_RS04060
uniprot id: A0A378XDE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

90244:I6G29 RS09495
gene id: 90244:I6G29_RS09495
uniprot id: A0A378XIA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

90244:I6G29 RS03570
gene id: 90244:I6G29_RS03570
uniprot id: A0A378XF79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

90244:I6G29 RS02480
gene id: 90244:I6G29_RS02480
uniprot id: A0A378XBS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

90244:I6G29 RS05085
gene id: 90244:I6G29_RS05085
uniprot id: A0A378XE29
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

90244:I6G29 RS12450
gene id: 90244:I6G29_RS12450
uniprot id: A0A378XI60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

90244:I6G29 RS13400
gene id: 90244:I6G29_RS13400
uniprot id: A0A378X8Y9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

90244:I6G29 RS09485
gene id: 90244:I6G29_RS09485
uniprot id: A0A378XHH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

90244:I6G29 RS10095
gene id: 90244:I6G29_RS10095
uniprot id: A0A378XIS4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

90244:I6G29 RS11360
gene id: 90244:I6G29_RS11360
uniprot id: A0A378XJG8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

90244:I6G29 RS02005
gene id: 90244:I6G29_RS02005
uniprot id: A0A378XBA8
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS04970
gene id: 90244:I6G29_RS04970
uniprot id: A0A378XDN3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

90244:I6G29 RS12475
gene id: 90244:I6G29_RS12475
uniprot id: A0A378XK26
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

90244:I6G29 RS01120
gene id: 90244:I6G29_RS01120
uniprot id: A0A378XD84
names: Subcellular Location Annotation
messages: Cytoplasm

90244:I6G29 RS02045
gene id: 90244:I6G29_RS02045
uniprot id: A0A378XBL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

90244:I6G29 RS10495
gene id: 90244:I6G29_RS10495
uniprot id: A0A378XJJ4
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

90244:I6G29 RS04415
gene id: 90244:I6G29_RS04415
uniprot id: A0A378XDB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

90244:I6G29 RS02655
gene id: 90244:I6G29_RS02655
uniprot id: A0A378XF15
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

90244:I6G29 RS00410
gene id: 90244:I6G29_RS00410
uniprot id: A0A378X991
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

90244:I6G29 RS06620
gene id: 90244:I6G29_RS06620
uniprot id: A0A378XE84
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

90244:I6G29 RS07045
gene id: 90244:I6G29_RS07045
uniprot id: A0A378XEG9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

90244:I6G29 RS03090
gene id: 90244:I6G29_RS03090
uniprot id: A0A378XCT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

90244:I6G29 RS11430
gene id: 90244:I6G29_RS11430
uniprot id: A0A378XJA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

90244:I6G29 RS08300
gene id: 90244:I6G29_RS08300
uniprot id: A0A378XFX1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

90244:I6G29 RS08375
gene id: 90244:I6G29_RS08375
uniprot id: A0A378XGU4
names: Similarity
messages: Belongs to the PrpF family.

90244:I6G29 RS12730
gene id: 90244:I6G29_RS12730
uniprot id: A0A378XK75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

90244:I6G29 RS07890
gene id: 90244:I6G29_RS07890
uniprot id: A0A378XHH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

90244:I6G29 RS07705
gene id: 90244:I6G29_RS07705
uniprot id: A0A378XFL1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

90244:I6G29 RS13100
gene id: 90244:I6G29_RS13100
uniprot id: A0A378XKF3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

90244:I6G29 RS11105
gene id: 90244:I6G29_RS11105
uniprot id: A0A378XGQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

90244:I6G29 RS00655
gene id: 90244:I6G29_RS00655
uniprot id: A0A378XB03
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS08780
gene id: 90244:I6G29_RS08780
uniprot id: A0A378XH28
names: Similarity
messages: Belongs to the UDPGP type 2 family.

90244:I6G29 RS08545
gene id: 90244:I6G29_RS08545
uniprot id: A0A378XFJ2
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

90244:I6G29 RS10795
gene id: 90244:I6G29_RS10795
uniprot id: A0A378XHD4
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

90244:I6G29 RS10185
gene id: 90244:I6G29_RS10185
uniprot id: A0A378XH26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

90244:I6G29 RS05565
gene id: 90244:I6G29_RS05565
uniprot id: A0A378XG73
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

90244:I6G29 RS07980
gene id: 90244:I6G29_RS07980
uniprot id: A0A378XGK8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

90244:I6G29 RS12675
gene id: 90244:I6G29_RS12675
uniprot id: A0A378XKV2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

90244:I6G29 RS09190
gene id: 90244:I6G29_RS09190
uniprot id: A0A378XFX8
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

90244:I6G29 RS10890
gene id: 90244:I6G29_RS10890
uniprot id: A0A378XIF1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

90244:I6G29 RS05585
gene id: 90244:I6G29_RS05585
uniprot id: A0A378XEB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

90244:I6G29 RS07650
gene id: 90244:I6G29_RS07650
uniprot id: A0A378XGJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

90244:I6G29 RS04705
gene id: 90244:I6G29_RS04705
uniprot id: A0A378XG88
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

90244:I6G29 RS13420
gene id: 90244:I6G29_RS13420
uniprot id: A0A378XBA3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

90244:I6G29 RS01070
gene id: 90244:I6G29_RS01070
uniprot id: A0A378XA32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

90244:I6G29 RS05695
gene id: 90244:I6G29_RS05695
uniprot id: A0A378XGC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

90244:I6G29 RS04895
gene id: 90244:I6G29_RS04895
uniprot id: A0A378XDX9
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

90244:I6G29 RS11675
gene id: 90244:I6G29_RS11675
uniprot id: A0A378XJL7
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

90244:I6G29 RS07040
gene id: 90244:I6G29_RS07040
uniprot id: A0A378XF45
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

90244:I6G29 RS07920
gene id: 90244:I6G29_RS07920
uniprot id: A0A378XEX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

90244:I6G29 RS10515
gene id: 90244:I6G29_RS10515
uniprot id: A0A378XI90
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS03185
gene id: 90244:I6G29_RS03185
uniprot id: A0A378XCY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

90244:I6G29 RS01220
gene id: 90244:I6G29_RS01220
uniprot id: A0A378XBR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell inner membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

90244:I6G29 RS10530
gene id: 90244:I6G29_RS10530
uniprot id: A0A378XGD7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

90244:I6G29 RS00825
gene id: 90244:I6G29_RS00825
uniprot id: A0A378XCW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhE family.
messages: Cytoplasm
messages: Necessary for formate dehydrogenase activity.

90244:I6G29 RS01665
gene id: 90244:I6G29_RS01665
uniprot id: A0A378XCI9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

90244:I6G29 RS10930
gene id: 90244:I6G29_RS10930
uniprot id: A0A378XJ20
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

90244:I6G29 RS03155
gene id: 90244:I6G29_RS03155
uniprot id: A0A378XEY8
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

90244:I6G29 RS13020
gene id: 90244:I6G29_RS13020
uniprot id: A0A378XIH3
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

90244:I6G29 RS08220
gene id: 90244:I6G29_RS08220
uniprot id: A0A378XGR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

90244:I6G29 RS11910
gene id: 90244:I6G29_RS11910
uniprot id: A0A378XJS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

90244:I6G29 RS07235
gene id: 90244:I6G29_RS07235
uniprot id: A0A378XEU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

90244:I6G29 RS03905
gene id: 90244:I6G29_RS03905
uniprot id: A0A378XDB0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

90244:I6G29 RS11795
gene id: 90244:I6G29_RS11795
uniprot id: A0A378XIW9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

90244:I6G29 RS07865
gene id: 90244:I6G29_RS07865
uniprot id: A0A378XFK9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

90244:I6G29 RS11425
gene id: 90244:I6G29_RS11425
uniprot id: A0A378XJG3
names: Similarity
messages: Belongs to the HesB/IscA family.

90244:I6G29 RS00075
gene id: 90244:I6G29_RS00075
uniprot id: A0A379B172
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

90244:I6G29 RS04405
gene id: 90244:I6G29_RS04405
uniprot id: A0A378XFJ9
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

90244:I6G29 RS03245
gene id: 90244:I6G29_RS03245
uniprot id: A0A378XE24
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS13225
gene id: 90244:I6G29_RS13225
uniprot id: A0A378XIL8
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

90244:I6G29 RS00685
gene id: 90244:I6G29_RS00685
uniprot id: A0A378XC49
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

90244:I6G29 RS05955
gene id: 90244:I6G29_RS05955
uniprot id: A0A378XEK7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

90244:I6G29 RS09480
gene id: 90244:I6G29_RS09480
uniprot id: A0A378XIF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

90244:I6G29 RS09515
gene id: 90244:I6G29_RS09515
uniprot id: A0A378XGJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

90244:I6G29 RS00800
gene id: 90244:I6G29_RS00800
uniprot id: A0A378XC67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

90244:I6G29 RS11020
gene id: 90244:I6G29_RS11020
uniprot id: A0A378XJU5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

90244:I6G29 RS07775
gene id: 90244:I6G29_RS07775
uniprot id: A0A378XHH1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhD family.
messages: Cytoplasm
messages: Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.
messages: The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA.

90244:I6G29 RS02810
gene id: 90244:I6G29_RS02810
uniprot id: A0A378XDM1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

90244:I6G29 RS06000
gene id: 90244:I6G29_RS06000
uniprot id: A0A378XFL5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

90244:I6G29 RS08875
gene id: 90244:I6G29_RS08875
uniprot id: A0A378XI36
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

90244:I6G29 RS03255
gene id: 90244:I6G29_RS03255
uniprot id: A0A378XCW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

90244:I6G29 RS09865
gene id: 90244:I6G29_RS09865
uniprot id: A0A378XGS2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

90244:I6G29 RS11345
gene id: 90244:I6G29_RS11345
uniprot id: A0A378XHP0
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

90244:I6G29 RS10955
gene id: 90244:I6G29_RS10955
uniprot id: A0A378XGL5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

90244:I6G29 RS08925
gene id: 90244:I6G29_RS08925
uniprot id: A0A378XI44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

90244:I6G29 RS06780
gene id: 90244:I6G29_RS06780
uniprot id: A0A378XGU3
names: Caution
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

90244:I6G29 RS04425
gene id: 90244:I6G29_RS04425
uniprot id: A0A378XDM6
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

90244:I6G29 RS10990
gene id: 90244:I6G29_RS10990
uniprot id: A0A378XIH0
names: Similarity
messages: Belongs to the peptidase C40 family.

90244:I6G29 RS07010
gene id: 90244:I6G29_RS07010
uniprot id: A0A378XHI7
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.

90244:I6G29 RS10065
gene id: 90244:I6G29_RS10065
uniprot id: A0A378XIR3
names: Subcellular Location Annotation
messages: Membrane

90244:I6G29 RS08835
gene id: 90244:I6G29_RS08835
uniprot id: A0A378XIK4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

90244:I6G29 RS04305
gene id: 90244:I6G29_RS04305
uniprot id: A0A378XFH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

90244:I6G29 RS07260
gene id: 90244:I6G29_RS07260
uniprot id: A0A378XH72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.