89673:SLC44A1
gene id: 89673:SLC44A1
uniprot id: A0A6J2L566
uniprot id: A0A7E6DFR9
uniprot id: A0A7E6DFY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

89673:LOC114515208
gene id: 89673:LOC114515208
uniprot id: A0A6J2NCV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiA prenyltransferase family.
messages: Converts protoheme IX and farnesyl diphosphate to heme O.
messages: Membrane
messages: Mitochondrion membrane

89673:B3GNT7
gene id: 89673:B3GNT7
uniprot id: A0A6J2LJ96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

89673:GCNT3
gene id: 89673:GCNT3
uniprot id: A0A6J2LBY0
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

89673:GJC2
gene id: 89673:GJC2
uniprot id: A0A6J2NJL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

89673:LOC114495147
gene id: 89673:LOC114495147
uniprot id: A0A7E6DHZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

89673:LOC118496641
gene id: 89673:LOC118496641
uniprot id: A0A7E6E4P6
uniprot id: A0A7E6E4U0
names: Subcellular Location Annotation
messages: Nucleus

89673:MIS12
gene id: 89673:MIS12
uniprot id: A0A6J2NEN3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mis12 family.
messages: Component of the MIS12 complex composed of MIS12, DSN1, NSL1 and PMF1. Also interacts with KNL1, CBX3, CBX5, NDC80 and ZWINT.
messages: kinetochore

89673:PKNOX2
gene id: 89673:PKNOX2
uniprot id: A0A6J2MTH6
uniprot id: A0A7E6CU49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

89673:LOC114511114
gene id: 89673:LOC114511114
uniprot id: A0A7E6CPH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

89673:RAMP2
gene id: 89673:RAMP2
uniprot id: A0A6J2MBT5
uniprot id: A0A6J2MF66
uniprot id: A0A7E6EE09
uniprot id: A0A7E6EFL6
uniprot id: A0A7E6EFS6
names: Similarity
messages: Belongs to the RAMP family.

89673:AGRN
gene id: 89673:AGRN
uniprot id: A0A6J2LLL4
uniprot id: A0A6J2LMX5
uniprot id: A0A6J2LRY5
uniprot id: A0A7E6DPC2
uniprot id: A0A7E6DPC7
uniprot id: A0A7E6DPC8
uniprot id: A0A7E6DPW3
uniprot id: A0A7E6DPW6
uniprot id: A0A7E6DQ32
uniprot id: A0A7E6DQE5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114497386
gene id: 89673:LOC114497386
uniprot id: A0A6J2LSL7
names: Similarity
messages: Belongs to the CLCR family.

89673:LOC114496538
gene id: 89673:LOC114496538
uniprot id: A0A7E6DS21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL15 family.
messages: Cytoplasm

89673:SUCLG2
gene id: 89673:SUCLG2
uniprot id: A0A6J2M1L5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family. GTP-specific subunit beta subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
messages: Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for GTP.
messages: Mitochondrion

89673:PTBP1
gene id: 89673:PTBP1
uniprot id: A0A6J2MBG8
uniprot id: A0A6J2MGN6
names: Subcellular Location Annotation
messages: Nucleus

89673:CREBL2
gene id: 89673:CREBL2
uniprot id: A0A6J2N7T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Nucleus

89673:CD36
gene id: 89673:CD36
uniprot id: A0A6J2MTS8
names: Similarity
messages: Belongs to the CD36 family.

89673:LOC114492295
gene id: 89673:LOC114492295
uniprot id: A0A6J2L496
uniprot id: A0A7E6DE09
uniprot id: A0A7E6DE22
uniprot id: A0A7E6DE33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

89673:SEC31B
gene id: 89673:SEC31B
uniprot id: A0A6J2LTJ7
uniprot id: A0A7E6DV00
uniprot id: A0A7E6DV42
uniprot id: A0A7E6DVK2
uniprot id: A0A7E6DVW8
uniprot id: A0A7E6DVX5
uniprot id: A0A7E6DWC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC31 family.
messages: Endoplasmic reticulum membrane

89673:LIPE
gene id: 89673:LIPE
uniprot id: A0A6J2N2S6
uniprot id: A0A6J2N2T9
uniprot id: A0A6J2N883
uniprot id: A0A7E6CP32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 'GDXG' lipolytic enzyme family.
messages: Cell membrane
messages: Lipid droplet
messages: caveola
messages: cytosol

89673:LOC114498470
gene id: 89673:LOC114498470
uniprot id: A0A6J2LR25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens.
messages: Belongs to the IL-1 family.
messages: Secreted

89673:RNF145
gene id: 89673:RNF145
uniprot id: A0A6J2N0W6
uniprot id: A0A7E6CT06
names: Subcellular Location Annotation
messages: Membrane

89673:PSMC4
gene id: 89673:PSMC4
uniprot id: A0A6J2N6X8
names: Similarity
messages: Belongs to the AAA ATPase family.

89673:CD82
gene id: 89673:CD82
uniprot id: A0A7E6E0W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

89673:SLC12A6
gene id: 89673:SLC12A6
uniprot id: A0A6J2KX87
uniprot id: A0A6J2L171
uniprot id: A0A6J2L322
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

89673:ATRX
gene id: 89673:ATRX
uniprot id: A0A6J2MI61
uniprot id: A0A7E6D0V5
uniprot id: A0A7E6D0W1
uniprot id: A0A7E6D0Y0
uniprot id: A0A7E6D122
uniprot id: A0A7E6D1T2
uniprot id: A0A7E6D1T8
uniprot id: A0A7E6D3N0
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

89673:LOC114506918
gene id: 89673:LOC114506918
uniprot id: A0A7E6CGU5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

89673:LOC114503625
gene id: 89673:LOC114503625
uniprot id: A0A7E6EGE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

89673:SIDT2
gene id: 89673:SIDT2
uniprot id: A0A7E6E354
uniprot id: A0A7E6E3Q3
uniprot id: A0A7E6E3Q8
uniprot id: A0A7E6E3V2
uniprot id: A0A7E6E4N0
uniprot id: A0A7E6E4N5
uniprot id: A0A7E6E4S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SID1 family.
messages: Membrane

89673:PSMD13
gene id: 89673:PSMD13
uniprot id: A0A6J2LXQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S11 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP). The regulatory particle is made of a lid composed of 9 subunits including PSMD13, a base containing 6 ATPases and few additional components.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

89673:ENTPD5
gene id: 89673:ENTPD5
uniprot id: A0A6J2L887
uniprot id: A0A6J2LCW1
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

89673:LOC114514639
gene id: 89673:LOC114514639
uniprot id: A0A6J2NCY5
names: Function
names: Similarity
messages: Belongs to the E(R) family.
messages: May have a role in the cell cycle.

89673:CSGALNACT2
gene id: 89673:CSGALNACT2
uniprot id: A0A6J2LRM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

89673:ATP6V1C1
gene id: 89673:ATP6V1C1
uniprot id: A0A6J2NB02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits.

89673:LOC114491765
gene id: 89673:LOC114491765
uniprot id: A0A6J2L4M5
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

89673:PRPS2
gene id: 89673:PRPS2
uniprot id: A0A6J2MIG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family.
messages: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
messages: Homodimer. The active form is probably a hexamer composed of 3 homodimers.

89673:TSPAN2
gene id: 89673:TSPAN2
uniprot id: A0A6J2KTN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

89673:NPEPPS
gene id: 89673:NPEPPS
uniprot id: A0A6J2M454
uniprot id: A0A6J2M998
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Membrane

89673:CNOT9
gene id: 89673:CNOT9
uniprot id: A0A6J2LBA9
uniprot id: A0A6J2LC54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT9 family.
messages: P-body

89673:SLC16A11
gene id: 89673:SLC16A11
uniprot id: A0A6J2NJ93
uniprot id: A0A7E6ECI9
uniprot id: A0A7E6EDC2
names: Subcellular Location Annotation
messages: Membrane

89673:MRPS31
gene id: 89673:MRPS31
uniprot id: A0A6J2MQY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS31 family.
messages: Mitochondrion

89673:SSTR1
gene id: 89673:SSTR1
uniprot id: A0A7E6E093
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:ITGAE
gene id: 89673:ITGAE
uniprot id: A0A7E6ECP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

89673:CYRIA
gene id: 89673:CYRIA
uniprot id: A0A7E6DXU7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CYRI family.
messages: Interacts with RAC1 (GTP-bound form preferentially).
messages: Membrane

89673:AK1
gene id: 89673:AK1
uniprot id: A0A6J2LTW8
uniprot id: A0A6J2LYX8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK1 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

89673:SERINC4
gene id: 89673:SERINC4
uniprot id: A0A6J2L5W2
uniprot id: A0A7E6EB32
uniprot id: A0A7E6EB37
uniprot id: A0A7E6EB42
uniprot id: A0A7E6EBP6
uniprot id: A0A7E6EBQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

89673:EIF4EBP1
gene id: 89673:EIF4EBP1
uniprot id: A0A6J2MXY5
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

89673:LOC114510112
gene id: 89673:LOC114510112
uniprot id: A0A6J2N3T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL15 family.
messages: Cytoplasm

89673:PTGES
gene id: 89673:PTGES
uniprot id: A0A6J2MM57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Membrane

89673:UNC93A
gene id: 89673:UNC93A
uniprot id: A0A6J2KX90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

89673:CRH
gene id: 89673:CRH
uniprot id: A0A6J2NB19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

89673:RPL7
gene id: 89673:RPL7
uniprot id: A0A6J2M339
uniprot id: A0A6J2M4L3
uniprot id: A0A7E6E6J2
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

89673:LOC114501573
gene id: 89673:LOC114501573
uniprot id: A0A7E6E7P9
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

89673:USE1
gene id: 89673:USE1
uniprot id: A0A6J2M7T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the USE1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:YTHDF1
gene id: 89673:YTHDF1
uniprot id: A0A6J2MK52
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

89673:LARS1
gene id: 89673:LARS1
uniprot id: A0A6J2MSP1
uniprot id: A0A7E6CU17
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

89673:GOT2
gene id: 89673:GOT2
uniprot id: A0A6J2KT27
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

89673:PARP12
gene id: 89673:PARP12
uniprot id: A0A6J2MR72
names: Similarity
messages: Belongs to the ARTD/PARP family.

89673:LOC114513021
gene id: 89673:LOC114513021
uniprot id: A0A6J2N812
uniprot id: A0A7E6D7K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

89673:LOC114490753
gene id: 89673:LOC114490753
uniprot id: A0A7E6D9W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

89673:CDK5
gene id: 89673:CDK5
uniprot id: A0A7E6CIY9
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:CMTM4
gene id: 89673:CMTM4
uniprot id: A0A6J2KQW2
uniprot id: A0A7E6CNX1
names: Subcellular Location Annotation
messages: Membrane

89673:LMLN
gene id: 89673:LMLN
uniprot id: A0A6J2L1G7
uniprot id: A0A6J2L4W6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M8 family.
messages: Binds 1 zinc ion per subunit.

89673:CKAP2
gene id: 89673:CKAP2
uniprot id: A0A6J2MSW8
uniprot id: A0A6J2MXT2
uniprot id: A0A7E6CJL7
uniprot id: A0A7E6CJR6
uniprot id: A0A7E6CJS0
uniprot id: A0A7E6CLP2
names: Similarity
messages: Belongs to the CKAP2 family.

89673:LOC114499468
gene id: 89673:LOC114499468
uniprot id: A0A6J2LZP8
names: Similarity
messages: Belongs to the folate receptor family.

89673:RNASE9
gene id: 89673:RNASE9
uniprot id: A0A6J2KXI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

89673:DDX1
gene id: 89673:DDX1
uniprot id: A0A6J2LVT0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX1 subfamily.
messages: Cytoplasmic granule
messages: RNA helicase.
messages: The helicase domain is involved in the stimulation of RELA transcriptional activity.

89673:ALDH7A1
gene id: 89673:ALDH7A1
uniprot id: A0A6J2MKC6
uniprot id: A0A7E6DB59
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

89673:EIF2B1
gene id: 89673:EIF2B1
uniprot id: A0A6J2MUT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.
messages: Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
messages: Complex of five different subunits; alpha, beta, gamma, delta and epsilon.

89673:KCNC2
gene id: 89673:KCNC2
uniprot id: A0A6J2NB43
uniprot id: A0A6J2NBH0
uniprot id: A0A7E6D5M1
uniprot id: A0A7E6D5P2
uniprot id: A0A7E6D5P7
uniprot id: A0A7E6D5R2
uniprot id: A0A7E6D6A7
uniprot id: A0A7E6D8G1
uniprot id: A0A7E6D8G8
names: Subcellular Location Annotation
messages: Membrane

89673:P3H2
gene id: 89673:P3H2
uniprot id: A0A6J2KZZ2
names: Similarity
messages: Belongs to the leprecan family.

89673:PHETA1
gene id: 89673:PHETA1
uniprot id: A0A7E6CUC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sesquipedalian family.
messages: Early endosome
messages: Forms homodimers and heterodimers with PHETA. Interacts with OCRL and INPP5B.
messages: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
messages: Recycling endosome
messages: clathrin-coated vesicle
messages: trans-Golgi network

89673:LAMC1
gene id: 89673:LAMC1
uniprot id: A0A6J2N8B5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

89673:HNRNPC
gene id: 89673:HNRNPC
uniprot id: A0A6J2KXA9
uniprot id: A0A6J2KXV8
uniprot id: A0A6J2KXW2
uniprot id: A0A7E6E4W2
uniprot id: A0A7E6E5F0
uniprot id: A0A7E6E5I5
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

89673:ELOVL7
gene id: 89673:ELOVL7
uniprot id: A0A6J2LVT8
uniprot id: A0A7E6DA85
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Belongs to the ELO family. ELOVL7 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0-, or C26:0-CoAs. May participate to the production of saturated and polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

89673:ARF5
gene id: 89673:ARF5
uniprot id: A0A6J2MLT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

89673:LOC118498517
gene id: 89673:LOC118498517
uniprot id: A0A7E6D0Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

89673:DOK5
gene id: 89673:DOK5
uniprot id: A0A6J2MIK9
uniprot id: A0A7E6CG41
names: Similarity
messages: Belongs to the DOK family. Type B subfamily.

89673:GCSH
gene id: 89673:GCSH
uniprot id: A0A6J2KU50
uniprot id: A0A7E6CPZ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

89673:C6H11orf49
gene id: 89673:C6H11orf49
uniprot id: A0A6J2LUU9
uniprot id: A0A6J2LYQ9
uniprot id: A0A6J2LZC1
uniprot id: A0A7E6E1J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSTPP1 family.
messages: cytoskeleton

89673:TMED10
gene id: 89673:TMED10
uniprot id: A0A6J2LAK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:TBXT
gene id: 89673:TBXT
uniprot id: A0A6J2L0J2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

89673:LOC114505457
gene id: 89673:LOC114505457
uniprot id: A0A7E6D127
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: lamellipodium

89673:LOC114505033
gene id: 89673:LOC114505033
uniprot id: A0A7E6CZA5
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

89673:PLK3
gene id: 89673:PLK3
uniprot id: A0A6J2LP83
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

89673:SEMA4F
gene id: 89673:SEMA4F
uniprot id: A0A6J2M1E6
uniprot id: A0A6J2M5M8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:DHODH
gene id: 89673:DHODH
uniprot id: A0A6J2KSD9
uniprot id: A0A7E6CM94
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. Required for UMP biosynthesis via de novo pathway.
messages: Mitochondrion inner membrane

89673:CHST6
gene id: 89673:CHST6
uniprot id: A0A6J2KT77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

89673:LOC114495073
gene id: 89673:LOC114495073
uniprot id: A0A7E6DHJ6
names: Subcellular Location Annotation
messages: Nucleus

89673:SKOR2
gene id: 89673:SKOR2
uniprot id: A0A6J2MMH2
names: Similarity
messages: Belongs to the SKI family.

89673:CPN1
gene id: 89673:CPN1
uniprot id: A0A6J2LMZ4
names: Similarity
messages: Belongs to the peptidase M14 family.

89673:ACTRT3
gene id: 89673:ACTRT3
uniprot id: A0A6J2KY98
uniprot id: A0A7E6D2Q7
names: Similarity
messages: Belongs to the actin family.

89673:SLC1A3
gene id: 89673:SLC1A3
uniprot id: A0A6J2MM03
uniprot id: A0A7E6D9Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

89673:SLC7A6
gene id: 89673:SLC7A6
uniprot id: A0A6J2KWV5
uniprot id: A0A7E6CLY8
uniprot id: A0A7E6CM19
names: Subcellular Location Annotation
messages: Membrane

89673:GFM1
gene id: 89673:GFM1
uniprot id: A0A6J2KY12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis.
messages: Mitochondrion

89673:LOC114498404
gene id: 89673:LOC114498404
uniprot id: A0A6J2LRY4
uniprot id: A0A6J2M5N8
uniprot id: A0A7E6E332
uniprot id: A0A7E6E337
uniprot id: A0A7E6E3N8
uniprot id: A0A7E6E3T1
uniprot id: A0A7E6E4L5
uniprot id: A0A7E6E4Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Cell membrane
messages: Membrane
messages: Metal transporter.

89673:LOC114499069
gene id: 89673:LOC114499069
uniprot id: A0A6J2LU10
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114492678
gene id: 89673:LOC114492678
uniprot id: A0A7E6E0D2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

89673:OAT
gene id: 89673:OAT
uniprot id: A0A6J2LQV2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

89673:EML4
gene id: 89673:EML4
uniprot id: A0A6J2LS89
uniprot id: A0A6J2LW45
names: Similarity
messages: Belongs to the WD repeat EMAP family.

89673:LOC114499014
gene id: 89673:LOC114499014
uniprot id: A0A6J2LY78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ELSPBP1
gene id: 89673:ELSPBP1
uniprot id: A0A6J2N1K0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114494628
gene id: 89673:LOC114494628
uniprot id: A0A6J2LE88
uniprot id: A0A6J2LIS1
uniprot id: A0A7E6DLX5
uniprot id: A0A7E6DME8
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

89673:LOC114489888
gene id: 89673:LOC114489888
uniprot id: A0A6J2KY25
uniprot id: A0A6J2KZP9
uniprot id: A0A7E6D1I1
uniprot id: A0A7E6D1I8
uniprot id: A0A7E6D1J2
uniprot id: A0A7E6D1J3
uniprot id: A0A7E6D1M5
uniprot id: A0A7E6D1N2
uniprot id: A0A7E6D2E6
uniprot id: A0A7E6D2F1
uniprot id: A0A7E6D491
uniprot id: A0A7E6D498
uniprot id: A0A7E6D4A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTX family.
messages: Nucleus

89673:MED15
gene id: 89673:MED15
uniprot id: A0A6J2MWD6
uniprot id: A0A6J2N1K5
uniprot id: A0A7E6CR73
uniprot id: A0A7E6CR79
uniprot id: A0A7E6CRA2
uniprot id: A0A7E6CRA7
uniprot id: A0A7E6CRK8
uniprot id: A0A7E6CRN0
uniprot id: A0A7E6CRN7
uniprot id: A0A7E6CTW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 15 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

89673:CHM
gene id: 89673:CHM
uniprot id: A0A6J2MHQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.

89673:ESRRB
gene id: 89673:ESRRB
uniprot id: A0A6J2L7R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

89673:RNF4
gene id: 89673:RNF4
uniprot id: A0A6J2L208
names: Subcellular Location Annotation
messages: Nucleus

89673:RPL10L
gene id: 89673:RPL10L
uniprot id: A0A6J2L5X2
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

89673:DNAJC2
gene id: 89673:DNAJC2
uniprot id: A0A7E6CGQ3
names: Function
messages: Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain. When nuclear, mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at 'Lys-119' (H2AK119ub), and promotes the displacement of the polycomb PRC1 complex from chromatin, thereby facilitating transcription activation.

89673:LOC114488180
gene id: 89673:LOC114488180
uniprot id: A0A6J2KUC1
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

89673:SCARB1
gene id: 89673:SCARB1
uniprot id: A0A6J2MWQ9
uniprot id: A0A7E6CUX4
names: Similarity
messages: Belongs to the CD36 family.

89673:ABCC1
gene id: 89673:ABCC1
uniprot id: A0A6J2LHY4
uniprot id: A0A7E6DBM6
uniprot id: A0A7E6DCV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

89673:LOC114498931
gene id: 89673:LOC114498931
uniprot id: A0A6J2LTT2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:PML
gene id: 89673:PML
uniprot id: A0A6J2L747
uniprot id: A0A6J2LD37
uniprot id: A0A7E6DXK7
uniprot id: A0A7E6DXS0
uniprot id: A0A7E6DY29
uniprot id: A0A7E6DY57
uniprot id: A0A7E6DYZ2
uniprot id: A0A7E6DYZ6
uniprot id: A0A7E6DZ02
names: Subcellular Location Annotation
messages: Cytoplasm

89673:LOC114499064
gene id: 89673:LOC114499064
uniprot id: A0A6J2LU05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CTU2
gene id: 89673:CTU2
uniprot id: A0A6J2KU39
uniprot id: A0A7E6CMX8
uniprot id: A0A7E6CQB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTU2/NCS2 family.
messages: Component of a complex at least composed of URM1, CTU2/NCS2 and CTU1/ATPBD3.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with CTU1/ATPBD3 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

89673:DNAJC24
gene id: 89673:DNAJC24
uniprot id: A0A6J2LYC3
uniprot id: A0A7E6E204
names: Similarity
messages: Belongs to the DPH4 family.

89673:OTOP3
gene id: 89673:OTOP3
uniprot id: A0A6J2MG71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

89673:FBXO48
gene id: 89673:FBXO48
uniprot id: A0A6J2LZY8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complex SCF(FBXO9) composed of CUL1, SKP1, RBX1 and FBXO9. Interacts with TTI1 and TELO2; when TTI1 and TELO2 are phosphorylated by CK2.
messages: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins and plays a role in several biological processes such as cell cycle, cell proliferation, or maintenance of chromosome stability. Ubiquitinates mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation. In contrast, does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex. As a consequence, mTORC1 is inactivated to restrain cell growth and protein translation, while mTORC2 is the activated due to the relief of feedback inhibition by mTORC1. Plays a role in maintaining epithelial cell survival by regulating the turn-over of chromatin modulator PRMT4 through ubiquitination and degradation by the proteasomal pathway. Regulates also PPARgamma stability by facilitating PPARgamma/PPARG ubiquitination and thereby plays a role in adipocyte differentiation.

89673:VAPA
gene id: 89673:VAPA
uniprot id: A0A6J2MMR7
uniprot id: A0A6J2MS75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:LOC114490344
gene id: 89673:LOC114490344
uniprot id: A0A6J2KY24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 6c family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

89673:WARS1
gene id: 89673:WARS1
uniprot id: A0A6J2L3G4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

89673:SERPINB11
gene id: 89673:SERPINB11
uniprot id: A0A7E6CGX2
names: Similarity
messages: Belongs to the serpin family.

89673:LOC114501386
gene id: 89673:LOC114501386
uniprot id: A0A7E6E6R6
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

89673:SPTBN1
gene id: 89673:SPTBN1
uniprot id: A0A6J2LW53
uniprot id: A0A6J2M169
uniprot id: A0A7E6DXF0
names: Similarity
messages: Belongs to the spectrin family.

89673:LOC114500989
gene id: 89673:LOC114500989
uniprot id: A0A6J2M5G6
names: Function
messages: Synthesizes selenophosphate from selenide and ATP.

89673:LOC114499837
gene id: 89673:LOC114499837
uniprot id: A0A6J2LYP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114500057
gene id: 89673:LOC114500057
uniprot id: A0A6J2LZK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ATPase subunit F6 family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.
messages: Mitochondrion
messages: Mitochondrion inner membrane

89673:NKX2-8
gene id: 89673:NKX2-8
uniprot id: A0A6J2L6A5
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC118498210
gene id: 89673:LOC118498210
uniprot id: A0A6J2KUL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:LOC114511981
gene id: 89673:LOC114511981
uniprot id: A0A6J2N472
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).
messages: Nucleus

89673:STT3A
gene id: 89673:STT3A
uniprot id: A0A6J2MUQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

89673:GRIA2
gene id: 89673:GRIA2
uniprot id: A0A6J2M4M0
uniprot id: A0A6J2M6R1
uniprot id: A0A6J2M9P9
uniprot id: A0A6J2MA86
uniprot id: A0A6J2MA92
uniprot id: A0A7E6E8A5
uniprot id: A0A7E6E919
uniprot id: A0A7E6E989
uniprot id: A0A7E6E9W0
uniprot id: A0A7E6EA95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

89673:LOC114488278
gene id: 89673:LOC114488278
uniprot id: A0A6J2KQR6
names: Function
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.
messages: Metallothioneins have a high content of cysteine residues that bind various heavy metals.

89673:SEC24C
gene id: 89673:SEC24C
uniprot id: A0A6J2LPW8
uniprot id: A0A6J2LQU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

89673:RP1
gene id: 89673:RP1
uniprot id: A0A7E6E6I1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114501826
gene id: 89673:LOC114501826
uniprot id: A0A7E6DB13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIIc family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits, encoded in the mitochondrial DNA, and 11 supernumerary subunits, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

89673:LOC114490176
gene id: 89673:LOC114490176
uniprot id: A0A6J2KZ47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:DMRTB1
gene id: 89673:DMRTB1
uniprot id: A0A7E6DW37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

89673:HMOX2
gene id: 89673:HMOX2
uniprot id: A0A6J2M379
names: Similarity
messages: Belongs to the heme oxygenase family.

89673:OPHN1
gene id: 89673:OPHN1
uniprot id: A0A6J2ME29
uniprot id: A0A6J2MJH6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Postsynapse
messages: Presynapse
messages: dendrite

89673:LOC114510764
gene id: 89673:LOC114510764
uniprot id: A0A6J2MZN9
names: Similarity
messages: Belongs to the MHC class I family.

89673:TECRL
gene id: 89673:TECRL
uniprot id: A0A6J2LCK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane

89673:EFNA2
gene id: 89673:EFNA2
uniprot id: A0A6J2MIC4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:SGCA
gene id: 89673:SGCA
uniprot id: A0A6J2ME51
names: Function
names: Similarity
messages: Belongs to the sarcoglycan alpha/epsilon family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.

89673:LOC114501767
gene id: 89673:LOC114501767
uniprot id: A0A6J2M464
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the secretoglobin family.
messages: Secreted

89673:TIMM17A
gene id: 89673:TIMM17A
uniprot id: A0A6J2N4Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex at least composed of TIMM23, TIMM17 (TIMM17A or TIMM17B) and TIMM50.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

89673:MAML2
gene id: 89673:MAML2
uniprot id: A0A6J2LWY8
uniprot id: A0A7E6E099
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

89673:RARS2
gene id: 89673:RARS2
uniprot id: A0A7E6DMH0
uniprot id: A0A7E6DNA6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

89673:PDRG1
gene id: 89673:PDRG1
uniprot id: A0A6J2MJH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Component of the PAQosome complex which is responsible for the biogenesis of several protein complexes and which consists of R2TP complex members RUVBL1, RUVBL2, RPAP3 and PIH1D1, URI complex members PFDN2, PFDN6, PDRG1, UXT and URI1 as well as ASDURF, POLR2E and DNAAF10/WDR92.
messages: Cytoplasm
messages: May play a role in chaperone-mediated protein folding.

89673:GPRC5D
gene id: 89673:GPRC5D
uniprot id: A0A6J2N666
uniprot id: A0A7E6D7F5
uniprot id: A0A7E6D7M7
uniprot id: A0A7E6D883
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:CGA
gene id: 89673:CGA
uniprot id: A0A6J2LIW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit alpha family.
messages: Heterodimer. The active hormones thyrotropin, lutropin and follitropin are heterodimers composed of CGA, a common alpha chain described here and a unique beta chain which confers their biological specificity to the hormones: TSHB for thyrotropin, LHB for lutropin and FSHB for follitropin.
messages: Secreted
messages: Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.

89673:SNRPB
gene id: 89673:SNRPB
uniprot id: A0A6J2MLV9
uniprot id: A0A6J2MR89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP SmB/SmN family.
messages: Nucleus

89673:SPIRE2
gene id: 89673:SPIRE2
uniprot id: A0A7E6CQE8
uniprot id: A0A7E6CQQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spire family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytoskeleton

89673:VKORC1
gene id: 89673:VKORC1
uniprot id: A0A6J2MJ38
uniprot id: A0A6J2MN90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:DUSP3
gene id: 89673:DUSP3
uniprot id: A0A6J2MDU6
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

89673:TSHZ3
gene id: 89673:TSHZ3
uniprot id: A0A7E6CQS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.
messages: Nucleus

89673:TAF1
gene id: 89673:TAF1
uniprot id: A0A7E6D022
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF1 family.
messages: Nucleus

89673:WDR83OS
gene id: 89673:WDR83OS
uniprot id: A0A6J2MCX1
uniprot id: A0A7E6EB90
names: Similarity
messages: Belongs to the Asterix family.

89673:BARX2
gene id: 89673:BARX2
uniprot id: A0A6J2MYF6
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114501989
gene id: 89673:LOC114501989
uniprot id: A0A7E6E5P1
uniprot id: A0A7E6E777
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family.
messages: nucleolus

89673:ETV6
gene id: 89673:ETV6
uniprot id: A0A6J2N4E8
uniprot id: A0A6J2N6C6
uniprot id: A0A6J2NAX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

89673:RAX2
gene id: 89673:RAX2
uniprot id: A0A6J2M4U2
uniprot id: A0A7E6EF63
names: Subcellular Location Annotation
messages: Nucleus

89673:PGAP3
gene id: 89673:PGAP3
uniprot id: A0A6J2M7T3
uniprot id: A0A6J2MCI8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP3 family.
messages: Golgi apparatus membrane
messages: Involved in the lipid remodeling steps of GPI-anchor maturation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:CRYAA
gene id: 89673:CRYAA
uniprot id: A0A6J2KZJ1
uniprot id: A0A6J2L050
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.
messages: Nucleus

89673:PXMP2
gene id: 89673:PXMP2
uniprot id: A0A6J2KVG3
uniprot id: A0A7E6CWF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

89673:TTC30B
gene id: 89673:TTC30B
uniprot id: A0A6J2LFP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TTC30/dfy-1/fleer family.
messages: Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip.
messages: cilium

89673:ABCB6
gene id: 89673:ABCB6
uniprot id: A0A7E6DI11
uniprot id: A0A7E6DIC6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Late endosome membrane
messages: Lysosome membrane
messages: Melanosome membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: extracellular exosome
messages: multivesicular body membrane

89673:SYPL2
gene id: 89673:SYPL2
uniprot id: A0A6J2KUJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

89673:LOC114494355
gene id: 89673:LOC114494355
uniprot id: A0A6J2LBQ4
uniprot id: A0A7E6DHM7
uniprot id: A0A7E6DHR9
uniprot id: A0A7E6DHV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

89673:GPC6
gene id: 89673:GPC6
uniprot id: A0A6J2MQH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

89673:TMA16
gene id: 89673:TMA16
uniprot id: A0A6J2MD80
uniprot id: A0A7E6E962
names: Function
names: Similarity
names: Subunit
messages: Associates with pre-60S ribosomal particles.
messages: Belongs to the TMA16 family.
messages: Involved in the biogenesis of the 60S ribosomal subunit in the nucleus.

89673:PPP1R15A
gene id: 89673:PPP1R15A
uniprot id: A0A6J2N8D2
uniprot id: A0A7E6CNE1
uniprot id: A0A7E6CNE9
names: Similarity
messages: Belongs to the PPP1R15 family.

89673:NETO2
gene id: 89673:NETO2
uniprot id: A0A7E6CQZ2
uniprot id: A0A7E6CTK4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:HDX
gene id: 89673:HDX
uniprot id: A0A6J2MKM8
uniprot id: A0A7E6D1Y6
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114502765
gene id: 89673:LOC114502765
uniprot id: A0A6J2M8A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

89673:DGCR2
gene id: 89673:DGCR2
uniprot id: A0A6J2MTB6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:TNFSF13B
gene id: 89673:TNFSF13B
uniprot id: A0A6J2MQR5
names: Similarity
messages: Belongs to the tumor necrosis factor family.

89673:LOC114504751
gene id: 89673:LOC114504751
uniprot id: A0A6J2MGG4
names: Similarity
messages: Belongs to the BEX family.

89673:CHRM3
gene id: 89673:CHRM3
uniprot id: A0A6J2N566
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

89673:MAPK8IP2
gene id: 89673:MAPK8IP2
uniprot id: A0A6J2N9S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JIP scaffold family.
messages: Cytoplasm

89673:FAM102A
gene id: 89673:FAM102A
uniprot id: A0A6J2LWJ6
names: Similarity
messages: Belongs to the EEIG family.

89673:LOC114492908
gene id: 89673:LOC114492908
uniprot id: A0A6J2LBC2
uniprot id: A0A7E6DIE0
uniprot id: A0A7E6DIH5
uniprot id: A0A7E6DII0
uniprot id: A0A7E6DIL2
uniprot id: A0A7E6DIM9
uniprot id: A0A7E6DIS5
names: Similarity
messages: Belongs to the SELO family.

89673:HDAC8
gene id: 89673:HDAC8
uniprot id: A0A6J2MI64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

89673:LOC114507833
gene id: 89673:LOC114507833
uniprot id: A0A6J2MN89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114497556
gene id: 89673:LOC114497556
uniprot id: A0A6J2LN10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Membrane

89673:CNOT6
gene id: 89673:CNOT6
uniprot id: A0A6J2MUX0
uniprot id: A0A6J2N010
uniprot id: A0A7E6CSU2
uniprot id: A0A7E6CVK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

89673:MED23
gene id: 89673:MED23
uniprot id: A0A6J2LA56
uniprot id: A0A6J2LAQ1
uniprot id: A0A7E6DNQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 23 family.
messages: Nucleus

89673:LOC114498448
gene id: 89673:LOC114498448
uniprot id: A0A7E6E1N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the jagunal family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:MRPS27
gene id: 89673:MRPS27
uniprot id: A0A6J2M6H9
names: Subcellular Location Annotation
messages: Mitochondrion

89673:INHA
gene id: 89673:INHA
uniprot id: A0A6J2LL62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Dimeric, linked by one or more disulfide bonds. Inhibin A is a dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition.
messages: Secreted

89673:SLC37A1
gene id: 89673:SLC37A1
uniprot id: A0A6J2L0H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Inorganic phosphate and glucose-6-phosphate antiporter. May transport cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocate inorganic phosphate into the opposite direction. Independent of a lumenal glucose-6-phosphatase. May not play a role in homeostatic regulation of blood glucose levels.
messages: Membrane

89673:INTS10
gene id: 89673:INTS10
uniprot id: A0A6J2MQA0
uniprot id: A0A6J2MQA6
uniprot id: A0A6J2MS31
uniprot id: A0A6J2MWI1
uniprot id: A0A7E6CKI5
uniprot id: A0A7E6CKK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 10 family.
messages: Nucleus

89673:LOC114490202
gene id: 89673:LOC114490202
uniprot id: A0A6J2L0V9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:AMH
gene id: 89673:AMH
uniprot id: A0A6J2MDC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Plays an important role in several reproductive functions. Induces Muellerian duct regression during male fetal sexual differentiation and plays a role in Leydig cell differentiation and function. In female acts as a negative regulator of the primordial to primary follicle transition and decreases FSH sensitivity of growing follicles. AMH signals by binding to a specific type-II receptor, AMHR2, that heterodimerizes with type-I receptors (ACVR1 and BMPR1A), and recruiting SMAD proteins that are translocated to the nucleus to regulate target gene expression.
messages: Secreted

89673:IYD
gene id: 89673:IYD
uniprot id: A0A6J2LHY9
names: Subcellular Location Annotation
messages: Cell membrane

89673:YES1
gene id: 89673:YES1
uniprot id: A0A6J2MJI7
uniprot id: A0A7E6CG21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

89673:LOC114490348
gene id: 89673:LOC114490348
uniprot id: A0A7E6E6S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TRABD2A
gene id: 89673:TRABD2A
uniprot id: A0A7E6E492
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIKI family.
messages: Cell membrane
messages: Divalent metal cations. Mn(2+) or Co(2+).
messages: Membrane
messages: Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation.

89673:CITED2
gene id: 89673:CITED2
uniprot id: A0A6J2LET8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

89673:PTPN12
gene id: 89673:PTPN12
uniprot id: A0A7E6CI10
uniprot id: A0A7E6CI43
uniprot id: A0A7E6CIB0
uniprot id: A0A7E6CIF5
uniprot id: A0A7E6CK41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 4 subfamily.
messages: Cytoplasm
messages: Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades.

89673:SLC6A7
gene id: 89673:SLC6A7
uniprot id: A0A6J2N1G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

89673:MTMR11
gene id: 89673:MTMR11
uniprot id: A0A7E6CVJ8
uniprot id: A0A7E6CW01
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

89673:LOC114505747
gene id: 89673:LOC114505747
uniprot id: A0A7E6D0C4
names: Similarity
messages: Belongs to the RASGRP family.

89673:KCNS1
gene id: 89673:KCNS1
uniprot id: A0A6J2MRK3
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114501027
gene id: 89673:LOC114501027
uniprot id: A0A6J2M5K8
names: Function
names: Similarity
messages: Belongs to the PET191 family.
messages: Involved in an early step of the mitochondrial complex IV assembly process.

89673:MUSTN1
gene id: 89673:MUSTN1
uniprot id: A0A6J2M3E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MUSTANG family.
messages: Nucleus

89673:PCOLCE
gene id: 89673:PCOLCE
uniprot id: A0A6J2MEL7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:SH3BP5L
gene id: 89673:SH3BP5L
uniprot id: A0A6J2NJB4
uniprot id: A0A7E6EAP5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

89673:DGKQ
gene id: 89673:DGKQ
uniprot id: A0A7E6D366
uniprot id: A0A7E6D3A8
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

89673:IWS1
gene id: 89673:IWS1
uniprot id: A0A6J2LCE2
uniprot id: A0A6J2LF75
uniprot id: A0A7E6DKH3
uniprot id: A0A7E6DKS3
uniprot id: A0A7E6DKU2
uniprot id: A0A7E6DL45
names: Subcellular Location Annotation
messages: Nucleus

89673:UXT
gene id: 89673:UXT
uniprot id: A0A6J2MKY8
names: Similarity
messages: Belongs to the UXT family.

89673:LOC114497455
gene id: 89673:LOC114497455
uniprot id: A0A6J2LPV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Membrane
messages: Microsome membrane

89673:TP53BP1
gene id: 89673:TP53BP1
uniprot id: A0A7E6E9B9
names: Subcellular Location Annotation
messages: Nucleus

89673:CTSE
gene id: 89673:CTSE
uniprot id: A0A6J2N491
names: Similarity
messages: Belongs to the peptidase A1 family.

89673:MPC1
gene id: 89673:MPC1
uniprot id: A0A6J2KX70
uniprot id: A0A7E6DNW2
uniprot id: A0A7E6DPY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

89673:ARRDC2
gene id: 89673:ARRDC2
uniprot id: A0A7E6E9X9
uniprot id: A0A7E6EBJ3
names: Similarity
messages: Belongs to the arrestin family.

89673:LOC114510289
gene id: 89673:LOC114510289
uniprot id: A0A6J2N451
uniprot id: A0A6J2N455
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

89673:FGF23
gene id: 89673:FGF23
uniprot id: A0A6J2N9E2
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

89673:VPS37B
gene id: 89673:VPS37B
uniprot id: A0A6J2N2Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

89673:LOC114507970
gene id: 89673:LOC114507970
uniprot id: A0A7E6CHR3
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

89673:MMP24
gene id: 89673:MMP24
uniprot id: A0A6J2ML45
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

89673:ABCA12
gene id: 89673:ABCA12
uniprot id: A0A7E6DIF7
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114490334
gene id: 89673:LOC114490334
uniprot id: A0A6J2L391
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:KCNH4
gene id: 89673:KCNH4
uniprot id: A0A6J2MFD2
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

89673:LOC114493970
gene id: 89673:LOC114493970
uniprot id: A0A6J2LAW8
names: Similarity
messages: Belongs to the MHC class II family.

89673:C12H19orf54
gene id: 89673:C12H19orf54
uniprot id: A0A6J2MZN8
names: Similarity
messages: Belongs to the ACTMAP family.

89673:LOC114497243
gene id: 89673:LOC114497243
uniprot id: A0A7E6DCU9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.

89673:HEXA
gene id: 89673:HEXA
uniprot id: A0A6J2LBF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 20 family.
messages: Lysosome

89673:LOC118499773
gene id: 89673:LOC118499773
uniprot id: A0A7E6DG63
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

89673:USP26
gene id: 89673:USP26
uniprot id: A0A6J2MM25
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

89673:ANAPC5
gene id: 89673:ANAPC5
uniprot id: A0A6J2MUX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC5 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: spindle

89673:BPIFC
gene id: 89673:BPIFC
uniprot id: A0A6J2N6E9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

89673:LOC114506432
gene id: 89673:LOC114506432
uniprot id: A0A6J2MKP8
names: Similarity
messages: Belongs to the vasopressin/oxytocin family.

89673:LUC7L3
gene id: 89673:LUC7L3
uniprot id: A0A6J2MC33
uniprot id: A0A6J2ME82
uniprot id: A0A6J2MEB7
uniprot id: A0A6J2MH76
uniprot id: A0A6J2MI39
uniprot id: A0A7E6EE20
names: Similarity
messages: Belongs to the Luc7 family.

89673:IRF3
gene id: 89673:IRF3
uniprot id: A0A6J2N0L8
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114505649
gene id: 89673:LOC114505649
uniprot id: A0A7E6D0H8
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

89673:CCR2
gene id: 89673:CCR2
uniprot id: A0A6J2M752
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:SLC13A1
gene id: 89673:SLC13A1
uniprot id: A0A6J2MSQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

89673:DLX4
gene id: 89673:DLX4
uniprot id: A0A7E6EDK4
names: Subcellular Location Annotation
messages: Nucleus

89673:TMEM126A
gene id: 89673:TMEM126A
uniprot id: A0A6J2LUI4
names: Subcellular Location Annotation
messages: Membrane

89673:CDK9
gene id: 89673:CDK9
uniprot id: A0A6J2MFI0
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:DYDC1
gene id: 89673:DYDC1
uniprot id: A0A6J2LLJ0
names: Similarity
messages: Belongs to the dpy-30 family.

89673:PSMA6
gene id: 89673:PSMA6
uniprot id: A0A6J2L922
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

89673:LTF
gene id: 89673:LTF
uniprot id: A0A6J2M8P2
names: Similarity
messages: Belongs to the transferrin family.

89673:BPNT2
gene id: 89673:BPNT2
uniprot id: A0A6J2NAC7
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

89673:LOC114501782
gene id: 89673:LOC114501782
uniprot id: A0A7E6E7M0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

89673:DHDDS
gene id: 89673:DHDDS
uniprot id: A0A6J2LLR3
uniprot id: A0A6J2LQ10
names: Similarity
messages: Belongs to the UPP synthase family.

89673:DECR2
gene id: 89673:DECR2
uniprot id: A0A6J2LTM1
uniprot id: A0A7E6DD89
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily.
messages: Monomer, dimer and oligomer.

89673:IFIH1
gene id: 89673:IFIH1
uniprot id: A0A6J2LG14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

89673:LOC114510219
gene id: 89673:LOC114510219
uniprot id: A0A6J2MYL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SERPINB1
gene id: 89673:SERPINB1
uniprot id: A0A6J2LSE3
uniprot id: A0A7E6DU21
names: Similarity
messages: Belongs to the serpin family.

89673:KRTCAP3
gene id: 89673:KRTCAP3
uniprot id: A0A6J2LRQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM54 family.
messages: Membrane

89673:LOC114515330
gene id: 89673:LOC114515330
uniprot id: A0A6J2NJK5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:JAG2
gene id: 89673:JAG2
uniprot id: A0A6J2LDL4
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

89673:EP300
gene id: 89673:EP300
uniprot id: A0A6J2N7F7
names: Subcellular Location Annotation
messages: Cytoplasm

89673:VEGFD
gene id: 89673:VEGFD
uniprot id: A0A7E6D069
uniprot id: A0A7E6D0F3
uniprot id: A0A7E6D135
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Secreted

89673:LOC114495968
gene id: 89673:LOC114495968
uniprot id: A0A6J2LLM2
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

89673:NPTX2
gene id: 89673:NPTX2
uniprot id: A0A6J2N2R7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114505429
gene id: 89673:LOC114505429
uniprot id: A0A6J2MLX6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

89673:LOC114497700
gene id: 89673:LOC114497700
uniprot id: A0A7E6DUN6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:ESYT2
gene id: 89673:ESYT2
uniprot id: A0A6J2MPB6
uniprot id: A0A6J2MTW1
uniprot id: A0A7E6CJ96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the extended synaptotagmin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:CLDN7
gene id: 89673:CLDN7
uniprot id: A0A6J2NJ67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

89673:LOC114503444
gene id: 89673:LOC114503444
uniprot id: A0A6J2MC46
names: Similarity
messages: Belongs to the cytochrome P450 family.

89673:NOL12
gene id: 89673:NOL12
uniprot id: A0A6J2N8P4
uniprot id: A0A7E6D8A5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRP17 family.
messages: Interacts with KIAA1191.
messages: nucleolus

89673:MRPL41
gene id: 89673:MRPL41
uniprot id: A0A6J2MA77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL41 family.
messages: Mitochondrion

89673:DOK4
gene id: 89673:DOK4
uniprot id: A0A6J2KQX6
uniprot id: A0A7E6CLH9
names: Similarity
messages: Belongs to the DOK family. Type B subfamily.

89673:CPT1C
gene id: 89673:CPT1C
uniprot id: A0A6J2MZK4
uniprot id: A0A7E6CNL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

89673:CAND2
gene id: 89673:CAND2
uniprot id: A0A6J2M8Z8
uniprot id: A0A7E6E5R1
names: Similarity
messages: Belongs to the CAND family.

89673:IMPA1
gene id: 89673:IMPA1
uniprot id: A0A6J2M319
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

89673:AP3S1
gene id: 89673:AP3S1
uniprot id: A0A6J2LR59
uniprot id: A0A6J2LV75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

89673:XPC
gene id: 89673:XPC
uniprot id: A0A6J2M5A7
uniprot id: A0A7E6E6K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPC family.
messages: Nucleus

89673:LOC114498815
gene id: 89673:LOC114498815
uniprot id: A0A6J2LTL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

89673:NFIC
gene id: 89673:NFIC
uniprot id: A0A6J2M4S6
uniprot id: A0A6J2M6G7
uniprot id: A0A6J2M6W5
uniprot id: A0A6J2M9U5
uniprot id: A0A6J2MAE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

89673:MAS1
gene id: 89673:MAS1
uniprot id: A0A6J2LAS6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:SERPINA9
gene id: 89673:SERPINA9
uniprot id: A0A6J2LAE5
names: Similarity
messages: Belongs to the serpin family.

89673:PSMA4
gene id: 89673:PSMA4
uniprot id: A0A6J2KRX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

89673:CDC6
gene id: 89673:CDC6
uniprot id: A0A6J2M9E7
uniprot id: A0A7E6EFL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.
messages: Nucleus

89673:ULK3
gene id: 89673:ULK3
uniprot id: A0A6J2LC48
uniprot id: A0A7E6DXL1
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:ERLEC1
gene id: 89673:ERLEC1
uniprot id: A0A6J2M0H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OS-9 family.
messages: Endoplasmic reticulum lumen
messages: Lectin involved in the quality control of the secretory pathway. As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, targets misfolded endoplasmic reticulum lumenal glycoproteins for degradation.

89673:CNTFR
gene id: 89673:CNTFR
uniprot id: A0A6J2MP61
names: Similarity
messages: Belongs to the type I cytokine receptor family. Type 3 subfamily.

89673:C4H6orf120
gene id: 89673:C4H6orf120
uniprot id: A0A6J2L2H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0669 family.
messages: May be involved in induction of apoptosis in CD4(+) T-cells, but not CD8(+) T-cells or hepatocytes.
messages: Secreted

89673:EMC7
gene id: 89673:EMC7
uniprot id: A0A6J2L1C2
names: Similarity
names: Subunit
messages: Belongs to the EMC7 family.
messages: Component of the ER membrane protein complex (EMC).

89673:LOC114505265
gene id: 89673:LOC114505265
uniprot id: A0A7E6CZZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs. Binds with high affinity to IPO4. Interacts with DDIT3.
messages: Cytoplasm
messages: May play a role during erythropoiesis through regulation of transcription factor DDIT3.
messages: Nucleus
messages: nucleolus

89673:ACKR3
gene id: 89673:ACKR3
uniprot id: A0A6J2LB92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:AIMP2
gene id: 89673:AIMP2
uniprot id: A0A6J2MWE3
uniprot id: A0A6J2N3C9
names: Subcellular Location Annotation
messages: Nucleus
messages: cytosol

89673:LOC114503019
gene id: 89673:LOC114503019
uniprot id: A0A7E6EB73
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LMF2
gene id: 89673:LMF2
uniprot id: A0A6J2NAA3
uniprot id: A0A7E6D8V6
uniprot id: A0A7E6D8Y6
uniprot id: A0A7E6D9N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase maturation factor family.
messages: Endoplasmic reticulum membrane
messages: Involved in the maturation of specific proteins in the endoplasmic reticulum.
messages: Membrane

89673:LOC114490177
gene id: 89673:LOC114490177
uniprot id: A0A6J2L2Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:USP20
gene id: 89673:USP20
uniprot id: A0A6J2MYH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP20/USP33 subfamily.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: centrosome
messages: perinuclear region

89673:PNN
gene id: 89673:PNN
uniprot id: A0A6J2L338
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pinin family.
messages: Found in a mRNA splicing-dependent exon junction complex (EJC). Found in a complex with SR proteins. Found in a mRNP complex with RNPS1. Component of the PSAP complex consisting of RNPS1, SAP18 and PNN. Interacts with PNISR, CTBP1, CTBP2, KRT8, KRT18, KRT19, PS1D/PNO40, PPIG, RNPS1, SFRS4 and SRRM2. Identified in the spliceosome C complex.
messages: Nucleus speckle
messages: desmosome

89673:SHTN1
gene id: 89673:SHTN1
uniprot id: A0A6J2LPS9
uniprot id: A0A6J2LTX9
uniprot id: A0A7E6DWJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shootin family.
messages: Perikaryon
messages: axon
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

89673:LOC114491049
gene id: 89673:LOC114491049
uniprot id: A0A6J2L007
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CLDN20
gene id: 89673:CLDN20
uniprot id: A0A6J2LEG0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

89673:SERPINB9
gene id: 89673:SERPINB9
uniprot id: A0A7E6DTF4
names: Similarity
messages: Belongs to the serpin family. Ov-serpin subfamily.

89673:SCUBE2
gene id: 89673:SCUBE2
uniprot id: A0A6J2M257
uniprot id: A0A7E6E0E8
uniprot id: A0A7E6E0S3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:C4H6orf58
gene id: 89673:C4H6orf58
uniprot id: A0A6J2LF60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEG1 family.
messages: Secreted

89673:CDK5R1
gene id: 89673:CDK5R1
uniprot id: A0A6J2MBW4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin-dependent kinase 5 activator family.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit and a regulatory subunit.
messages: Membrane

89673:ZSCAN16
gene id: 89673:ZSCAN16
uniprot id: A0A6J2KZ08
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114493931
gene id: 89673:LOC114493931
uniprot id: A0A6J2LAM2
uniprot id: A0A7E6DLA0
uniprot id: A0A7E6DLN5
uniprot id: A0A7E6DM10
names: Similarity
messages: Belongs to the MHC class I family.

89673:LOC114496814
gene id: 89673:LOC114496814
uniprot id: A0A7E6DP60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecE/SEC61-gamma family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:AURKB
gene id: 89673:AURKB
uniprot id: A0A6J2NJS2
uniprot id: A0A7E6EBB0
uniprot id: A0A7E6EC44
uniprot id: A0A7E6ED76
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.

89673:PLG
gene id: 89673:PLG
uniprot id: A0A6J2KX86
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Converted into plasmin by plasminogen activators, both plasminogen and its activator being bound to fibrin.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells.
messages: Secreted

89673:ALG9
gene id: 89673:ALG9
uniprot id: A0A6J2LV72
uniprot id: A0A7E6DZ32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:LOC114511186
gene id: 89673:LOC114511186
uniprot id: A0A6J2N1E8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

89673:LOC114503642
gene id: 89673:LOC114503642
uniprot id: A0A6J2MFN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:EPHB2
gene id: 89673:EPHB2
uniprot id: A0A6J2LQ75
uniprot id: A0A7E6DR16
uniprot id: A0A7E6DRI5
names: Subcellular Location Annotation
messages: Membrane

89673:ELP3
gene id: 89673:ELP3
uniprot id: A0A6J2MFT7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.

89673:NAP1L3
gene id: 89673:NAP1L3
uniprot id: A0A6J2MKV3
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

89673:LOC114505602
gene id: 89673:LOC114505602
uniprot id: A0A6J2MGL5
names: Similarity
messages: Belongs to the SMEK family.

89673:TMCO3
gene id: 89673:TMCO3
uniprot id: A0A6J2MQN3
uniprot id: A0A6J2MWX9
names: Subcellular Location Annotation
messages: Membrane

89673:AGO2
gene id: 89673:AGO2
uniprot id: A0A6J2ND23
uniprot id: A0A7E6E7U5
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argonaute family. Ago subfamily.
messages: Hydroxylated. 4-hydroxylation appears to enhance protein stability but is not required for miRNA-binding or endonuclease activity.
messages: Interacts with DICER1 through its Piwi domain and with TARBP2 during assembly of the RNA-induced silencing complex (RISC). Together, DICER1, AGO2 and TARBP2 constitute the trimeric RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC). Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. Note however that the term RISC has also been used to describe the trimeric RLC/miRLC. The formation of RISC complexes containing siRNAs rather than miRNAs appears to occur independently of DICER1. Interacts with AGO1. Also interacts with DDB1, DDX5, DDX6, DDX20, DHX30, DHX36, DDX47, DHX9, ELAVL, FXR1, GEMIN4, HNRNPF, IGF2BP1, ILF3, IMP8, MATR3, PABPC1, PRMT5, P4HA1, P4HB, RBM4, SART3, TNRC6A, TNRC6B, UPF1 and YBX1. Interacts with the P-body components DCP1A and XRN1. Associates with polysomes and messenger ribonucleoproteins (mNRPs). Interacts with RBM4; the interaction is modulated under stress-induced conditions, occurs under both cell proliferation and differentiation conditions and in an RNA-and phosphorylation-independent manner. Interacts with LIMD1, WTIP and AJUBA. Interacts with TRIM71. Interacts with APOBEC3G in an RNA-dependent manner. Interacts with APOBEC3A, APOBEC3C, APOBEC3F and APOBEC3H. Interacts with DICER1, TARBP2, EIF6, MOV10 and RPL7A (60S ribosome subunit); they form a large RNA-induced silencing complex (RISC). Interacts with FMR1. Interacts with ZFP36.
messages: Nucleus
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the mRNA specifically by AGO2. Binding of RISC to a partially complementary mRNA results in silencing through inhibition of translation, and this is independent of endonuclease activity. May inhibit translation initiation by binding to the 7-methylguanosine cap, thereby preventing the recruitment of the translation initiation factor eIF4-E. May also inhibit translation initiation via interaction with EIF6, which itself binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit. The inhibition of translational initiation leads to the accumulation of the affected mRNA in cytoplasmic processing bodies (P-bodies), where mRNA degradation may subsequently occur. In some cases RISC-mediated translational repression is also observed for miRNAs that perfectly match the 3' untranslated region (3'-UTR). Can also up-regulate the translation of specific mRNAs under certain growth conditions. Binds to the AU element of the 3'-UTR of the TNF (TNF-alpha) mRNA and up-regulates translation under conditions of serum starvation. Also required for transcriptional gene silencing (TGS), in which short RNAs known as antigene RNAs or agRNAs direct the transcriptional repression of complementary promoter regions.
messages: The Piwi domain may perform RNA cleavage by a mechanism similar to that of RNase H. However, while RNase H utilizes a triad of Asp-Asp-Glu (DDE) for metal ion coordination, this protein appears to utilize a triad of Asp-Asp-His (DDH).

89673:B3GAT1
gene id: 89673:B3GAT1
uniprot id: A0A6J2MWK2
uniprot id: A0A6J2MWL5
uniprot id: A0A7E6CRM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

89673:SMARCD1
gene id: 89673:SMARCD1
uniprot id: A0A6J2NC03
uniprot id: A0A7E6D9L2
names: Similarity
messages: Belongs to the SMARCD family.

89673:GLUL
gene id: 89673:GLUL
uniprot id: A0A6J2N3F6
uniprot id: A0A6J2N863
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamine synthetase family.
messages: Cell membrane
messages: Membrane
messages: Microsome
messages: Mitochondrion

89673:GRK2
gene id: 89673:GRK2
uniprot id: A0A6J2LYM9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

89673:LOC114500030
gene id: 89673:LOC114500030
uniprot id: A0A6J2LYJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:IPO8
gene id: 89673:IPO8
uniprot id: A0A6J2NBI2
names: Subcellular Location Annotation
messages: Cytoplasm

89673:MFF
gene id: 89673:MFF
uniprot id: A0A6J2LCR3
uniprot id: A0A6J2LHM3
uniprot id: A0A6J2LIK0
uniprot id: A0A7E6DHX2
uniprot id: A0A7E6DHX6
uniprot id: A0A7E6DI06
uniprot id: A0A7E6DI37
uniprot id: A0A7E6DI41
uniprot id: A0A7E6DI56
uniprot id: A0A7E6DI90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tango11 family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Peroxisome
messages: Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface.
messages: synaptic vesicle

89673:PIGK
gene id: 89673:PIGK
uniprot id: A0A6J2LLR8
names: Similarity
names: Subunit
messages: Belongs to the peptidase C13 family.
messages: Forms a complex with PIGT, PIGS, PIGU and GAA1.

89673:HACD3
gene id: 89673:HACD3
uniprot id: A0A6J2LC37
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:MED7
gene id: 89673:MED7
uniprot id: A0A6J2MWL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 7 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
messages: Component of the Mediator complex.
messages: Nucleus

89673:LOC114492662
gene id: 89673:LOC114492662
uniprot id: A0A6J2L7K2
names: Similarity
messages: Belongs to the GSKIP family.

89673:PPIL2
gene id: 89673:PPIL2
uniprot id: A0A6J2N1T9
uniprot id: A0A7E6CTQ8
uniprot id: A0A7E6CU81
uniprot id: A0A7E6CUH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.
messages: Nucleus

89673:FUT8
gene id: 89673:FUT8
uniprot id: A0A6J2L4S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 23 family.
messages: Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.
messages: Golgi stack membrane
messages: Membrane

89673:CCDC149
gene id: 89673:CCDC149
uniprot id: A0A6J2L9Q5
uniprot id: A0A6J2LDP9
names: Similarity
messages: Belongs to the CCDC149 family.

89673:FOXJ3
gene id: 89673:FOXJ3
uniprot id: A0A6J2LMP0
uniprot id: A0A6J2LNF2
names: Subcellular Location Annotation
messages: Nucleus

89673:FOXB2
gene id: 89673:FOXB2
uniprot id: A0A6J2L4Q8
names: Subcellular Location Annotation
messages: Nucleus

89673:HENMT1
gene id: 89673:HENMT1
uniprot id: A0A6J2KXT0
names: Similarity
messages: Belongs to the methyltransferase superfamily. HEN1 family.

89673:PJVK
gene id: 89673:PJVK
uniprot id: A0A6J2LC39
names: Similarity
messages: Belongs to the gasdermin family.

89673:LOC114500155
gene id: 89673:LOC114500155
uniprot id: A0A6J2M2X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114507288
gene id: 89673:LOC114507288
uniprot id: A0A6J2MLF7
names: Similarity
messages: Belongs to the MISS family.

89673:TBC1D24
gene id: 89673:TBC1D24
uniprot id: A0A6J2LET7
uniprot id: A0A6J2LFJ1
uniprot id: A0A6J2LGZ7
uniprot id: A0A7E6D946
uniprot id: A0A7E6D948
uniprot id: A0A7E6D972
uniprot id: A0A7E6D9C2
uniprot id: A0A7E6D9C7
uniprot id: A0A7E6DA15
uniprot id: A0A7E6DC41
names: Caution
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasmic vesicle membrane
messages: Interacts with ARF6.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Presynapse

89673:OXSR1
gene id: 89673:OXSR1
uniprot id: A0A6J2M4J8
uniprot id: A0A7E6E4V4
uniprot id: A0A7E6E4Z5
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

89673:GNRHR
gene id: 89673:GNRHR
uniprot id: A0A6J2L8P9
uniprot id: A0A6J2LDX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system.

89673:CSNK1G3
gene id: 89673:CSNK1G3
uniprot id: A0A6J2L4B8
uniprot id: A0A6J2L535
uniprot id: A0A6J2L6L9
uniprot id: A0A6J2LAH0
uniprot id: A0A7E6DB53
uniprot id: A0A7E6DBA2
uniprot id: A0A7E6DBM1
uniprot id: A0A7E6DCC8
uniprot id: A0A7E6DDF2
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

89673:PPFIBP1
gene id: 89673:PPFIBP1
uniprot id: A0A6J2N5I4
uniprot id: A0A6J2N7B4
uniprot id: A0A6J2N7M4
uniprot id: A0A6J2NCS3
uniprot id: A0A7E6D781
uniprot id: A0A7E6D7B7
uniprot id: A0A7E6D7V8
uniprot id: A0A7E6DA27
names: Similarity
messages: Belongs to the liprin family. Liprin-beta subfamily.

89673:LOC114492998
gene id: 89673:LOC114492998
uniprot id: A0A6J2L8W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 5A family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

89673:GRB7
gene id: 89673:GRB7
uniprot id: A0A6J2ME47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

89673:LOC114488214
gene id: 89673:LOC114488214
uniprot id: A0A6J2KUG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the p22phox family.
messages: Cell membrane
messages: Composed of a heavy chain (beta) and a light chain (alpha). Component of an NADPH oxidase complex composed of a heterodimer formed by the membrane proteins CYBA and CYBB and the cytosolic subunits NCF1, NCF2 and NCF4. Interacts with NCF1 (via SH3 domain).
messages: Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
messages: Membrane

89673:LYN
gene id: 89673:LYN
uniprot id: A0A6J2NHY6
uniprot id: A0A7E6E7N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

89673:ANXA2
gene id: 89673:ANXA2
uniprot id: A0A6J2L7B4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9.
messages: Membrane
messages: basement membrane

89673:RSPO2
gene id: 89673:RSPO2
uniprot id: A0A6J2NAI0
names: Similarity
messages: Belongs to the R-spondin family.

89673:RRAGB
gene id: 89673:RRAGB
uniprot id: A0A6J2MDA0
uniprot id: A0A6J2MFB4
uniprot id: A0A6J2MFB9
uniprot id: A0A6J2MFF0
uniprot id: A0A6J2MIL6
uniprot id: A0A6J2MJA1
uniprot id: A0A6J2MJA7
uniprot id: A0A7E6D068
uniprot id: A0A7E6D0U6
uniprot id: A0A7E6D0V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

89673:DLX6
gene id: 89673:DLX6
uniprot id: A0A6J2MPM7
names: Subcellular Location Annotation
messages: Nucleus

89673:PTEN
gene id: 89673:PTEN
uniprot id: A0A6J2LRJ7
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

89673:NIPAL3
gene id: 89673:NIPAL3
uniprot id: A0A6J2LPW3
uniprot id: A0A7E6DRK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

89673:TOMM40
gene id: 89673:TOMM40
uniprot id: A0A6J2N7C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

89673:BRCA1
gene id: 89673:BRCA1
uniprot id: A0A6J2MC80
uniprot id: A0A7E6EEV4
uniprot id: A0A7E6EFP3
uniprot id: A0A7E6EFU4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Chromosome
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Regulates centrosomal microtubule nucleation. Required for appropriate cell cycle arrests after ionizing irradiation in both the S-phase and the G2 phase of the cell cycle. Required for FANCD2 targeting to sites of DNA damage. Inhibits lipid synthesis by binding to inactive phosphorylated ACACA and preventing its dephosphorylation. Contributes to homologous recombination repair (HRR) via its direct interaction with PALB2, fine-tunes recombinational repair partly through its modulatory role in the PALB2-dependent loading of BRCA2-RAD51 repair machinery at DNA breaks. Component of the BRCA1-RBBP8 complex which regulates CHEK1 activation and controls cell cycle G2/M checkpoints on DNA damage via BRCA1-mediated ubiquitination of RBBP8. Acts as a transcriptional activator.
messages: Heterodimer with BARD1. Part of the BRCA1-associated genome surveillance complex (BASC), which contains BRCA1, MSH2, MSH6, MLH1, ATM, BLM, PMS2 and the MRE11-RAD50-NBN protein (MRN) complex. This association could be a dynamic process changing throughout the cell cycle and within subnuclear domains. Component of the BRCA1-A complex, at least composed of BRCA1, BARD1, UIMC1/RAP80, ABRAXAS1, BRCC3/BRCC36, BABAM2 and BABAM1/NBA1. Interacts (via the BRCT domains) with ABRAXAS1 (phosphorylated form); this is important for recruitment to sites of DNA damage. Can form a heterotetramer with two molecules of ABRAXAS1 (phosphorylated form). Component of the BRCA1-RBBP8 complex. Interacts (via the BRCT domains) with RBBP8 ('Ser-327' phosphorylated form); the interaction ubiquitinates RBBP8, regulates CHEK1 activation, and involves RBBP8 in BRCA1-dependent G2/M checkpoint control on DNA damage. Associates with RNA polymerase II holoenzyme. Interacts with SMC1A, NELFB, DCLRE1C, CLSPN. CHEK1, CHEK2, BAP1, BRCC3, UBXN1 and PCLAF. Interacts (via BRCT domains) with BRIP1 (phosphorylated form). Interacts with FANCD2 (ubiquitinated form). Interacts with H2AX (phosphorylated on 'Ser-140'). Interacts (via the BRCT domains) with ACACA (phosphorylated form); the interaction prevents dephosphorylation of ACACA. Part of a BRCA complex containing BRCA1, BRCA2 and PALB2. Interacts directly with PALB2; the interaction is essential for its function in HRR. Interacts directly with BRCA2; the interaction occurs only in the presence of PALB2 which serves as the bridging protein. Interacts (via the BRCT domains) with LMO4; the interaction represses the transcriptional activity of BRCA1. Interacts (via the BRCT domains) with CCAR2 (via N-terminus); the interaction represses the transcriptional activator activity of BRCA1. Interacts with EXD2. Interacts (via C-terminus) with DHX9; this interaction is direct and links BRCA1 to the RNA polymerase II holoenzyme.
messages: Nucleus

89673:CLDN3
gene id: 89673:CLDN3
uniprot id: A0A6J2LVA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the claudin family.
messages: Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN1 and CLDN2 homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

89673:LOC114506740
gene id: 89673:LOC114506740
uniprot id: A0A7E6CGI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

89673:TGM3
gene id: 89673:TGM3
uniprot id: A0A7E6CEW3
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

89673:NPPA
gene id: 89673:NPPA
uniprot id: A0A6J2LVT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the natriuretic peptide family.
messages: Cell projection
messages: Homodimer; disulfide-linked antiparallel dimer.
messages: Hormone produced in the kidneys that appears to be important for maintaining cardio-renal homeostasis. Mediates vasodilation, natriuresis and diuresis primarily in the renal system, in order to maintain the extracellular fluid volume and control the fluid-electrolyte balance. Specifically binds and stimulates cGMP production by renal transmembrane receptors, likely NPR1. Urodilatin not ANP, may be the natriuretic peptide responsible for the regulation of sodium and water homeostasis in the kidney.
messages: May have a role in cardio-renal homeostasis through regulation of diuresis and inhibiting aldosterone synthesis. In vitro, promotes the production of cGMP and induces vasodilation. May promote natriuresis, at least in part, by enhancing prostaglandin E2 synthesis resulting in the inhibition of renal Na+-K+-ATPase. May have a role in potassium excretion but not sodium excretion (natriuresis). Possibly enhances protein excretion in urine by decreasing proximal tubular protein reabsorption.
messages: May have a role in cardio-renal homeostasis through regulation of natriuresis and vasodilation. In vivo promotes natriuresis and in vitro, vasodilates renal artery strips.
messages: May have a role in cardio-renal homeostasis through regulation of natriuresis and vasodilation. In vivo promotes natriuresis. In vitro, selectively vasodilates intestinal and vascular smooth muscle strips.
messages: May have a role in cardio-renal homeostasis through regulation of natriuresis and vasodilation. In vivo promotes natriuresis. In vitro, selectively vasodilates intestinal smooth muscle but not vascular smooth muscle strips.
messages: May have a role in cardio-renal homeostasis through regulation of natriuresis, diuresis, and vasodilation. In vitro, promotes the production of cGMP and induces vasodilation. May promote natriuresis, at least in part, by enhancing prostaglandin E2 synthesis resulting in the inhibition of renal Na+-K+-ATPase. However reports on the involvement of this peptide in mammal blood volume and blood pressure homeostasis are conflicting; according to a report it is not sufficient to activate cGMP and does not inhibit collecting duct transport nor effect diuresis and natriuresis. Appears to bind to specific receptors that are distinct from the receptors bound by the atrial natriuretic and long-acting natriuretic peptides. Possibly functions in protein excretion in urine by maintaining the integrity of the proximal tubules and enhancing protein excretion by decreasing proximal tubular protein reabsorption.
messages: May have a role in cardio-renal homeostasis through regulation of natriuresis, diuresis, vasodilation, and inhibiting aldosterone synthesis. In vitro, promotes the production of cGMP and induces vasodilation. May promote natriuresis, at least in part, by enhancing prostaglandin E2 synthesis resulting in the inhibition of renal Na+-K+-ATPase (By similarity). However reports on the involvement of this peptide in mammal blood volume and blood pressure homeostasis are conflicting; according to a report, in vivo it is not sufficient to activate cGMP and does not inhibit collecting duct transport nor effect diuresis and natriuresis (By similarity). Appears to bind to specific receptors that are distinct from the receptors bound by atrial natriuretic peptide and vessel dilator. Possibly enhances protein excretion in urine by decreasing proximal tubular protein reabsorption.
messages: May have a role in cardio-renal homeostasis through regulation of regulation of natriuresis and vasodilation. In vivo promotes natriuresis. In vitro, vasodilates intestinal smooth muscle but not smooth muscle strips.
messages: Secreted

89673:LOC114503718
gene id: 89673:LOC114503718
uniprot id: A0A6J2MFV5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SRRT
gene id: 89673:SRRT
uniprot id: A0A7E6DBB9
names: Similarity
messages: Belongs to the ARS2 family.

89673:PTPN4
gene id: 89673:PTPN4
uniprot id: A0A6J2NBV4
uniprot id: A0A7E6DKK5
uniprot id: A0A7E6DKU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: May act at junctions between the membrane and the cytoskeleton.
messages: cytoskeleton

89673:SCAMP3
gene id: 89673:SCAMP3
uniprot id: A0A6J2KSV1
uniprot id: A0A6J2KY97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

89673:GSR
gene id: 89673:GSR
uniprot id: A0A6J2MWB2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: Maintains high levels of reduced glutathione in the cytosol.

89673:MYOC
gene id: 89673:MYOC
uniprot id: A0A6J2N9T0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:CENPH
gene id: 89673:CENPH
uniprot id: A0A6J2LUQ1
uniprot id: A0A7E6DAL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-H/MCM16 family.
messages: Nucleus
messages: kinetochore

89673:KCNMA1
gene id: 89673:KCNMA1
uniprot id: A0A7E6DW21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa1.1/KCNMA1 sub-subfamily.
messages: Membrane

89673:LOC114509180
gene id: 89673:LOC114509180
uniprot id: A0A6J2MYW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat HIR1 family.
messages: Nucleus
messages: Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

89673:GRIK3
gene id: 89673:GRIK3
uniprot id: A0A6J2LQE6
uniprot id: A0A6J2LUJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

89673:RSPO1
gene id: 89673:RSPO1
uniprot id: A0A6J2LUA0
names: Similarity
messages: Belongs to the R-spondin family.

89673:LOC114503540
gene id: 89673:LOC114503540
uniprot id: A0A6J2MAA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SRPX
gene id: 89673:SRPX
uniprot id: A0A6J2MMC2
uniprot id: A0A7E6CZJ8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:SLC25A18
gene id: 89673:SLC25A18
uniprot id: A0A6J2MT76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

89673:CWF19L2
gene id: 89673:CWF19L2
uniprot id: A0A6J2LYU8
uniprot id: A0A6J2M2S8
names: Similarity
messages: Belongs to the CWF19 family.

89673:ETNPPL
gene id: 89673:ETNPPL
uniprot id: A0A6J2L6H5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

89673:TSPAN4
gene id: 89673:TSPAN4
uniprot id: A0A6J2LV70
uniprot id: A0A7E6E340
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

89673:GBGT1
gene id: 89673:GBGT1
uniprot id: A0A6J2MG23
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Membrane

89673:GART
gene id: 89673:GART
uniprot id: A0A6J2L2B2
names: Similarity
messages: In the C-terminal section; belongs to the GART family.
messages: In the N-terminal section; belongs to the GARS family.
messages: In the central section; belongs to the AIR synthase family.

89673:ZFHX3
gene id: 89673:ZFHX3
uniprot id: A0A7E6CM53
names: Subcellular Location Annotation
messages: Nucleus

89673:SCAMP5
gene id: 89673:SCAMP5
uniprot id: A0A6J2L7A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

89673:WNT4
gene id: 89673:WNT4
uniprot id: A0A6J2LLU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

89673:LOC114498976
gene id: 89673:LOC114498976
uniprot id: A0A6J2LSM8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:LOC114500097
gene id: 89673:LOC114500097
uniprot id: A0A6J2M353
uniprot id: A0A7E6E273
uniprot id: A0A7E6E2C6
uniprot id: A0A7E6E338
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INCENP family.
messages: Midbody
messages: Nucleus
messages: kinetochore
messages: spindle

89673:CHST12
gene id: 89673:CHST12
uniprot id: A0A6J2MWP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

89673:SMARCA2
gene id: 89673:SMARCA2
uniprot id: A0A6J2LTI7
uniprot id: A0A6J2LXE2
uniprot id: A0A6J2LXS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

89673:ADRM1
gene id: 89673:ADRM1
uniprot id: A0A6J2MK08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADRM1 family.
messages: Cytoplasm
messages: Nucleus

89673:CDH2
gene id: 89673:CDH2
uniprot id: A0A6J2MNH8
uniprot id: A0A7E6CFW3
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

89673:TDP2
gene id: 89673:TDP2
uniprot id: A0A6J2L0W2
names: Subcellular Location Annotation
messages: PML body

89673:PARP10
gene id: 89673:PARP10
uniprot id: A0A7E6E871
names: Similarity
messages: Belongs to the ARTD/PARP family.

89673:GTF3C5
gene id: 89673:GTF3C5
uniprot id: A0A6J2LZF0
names: Subcellular Location Annotation
messages: Nucleus

89673:CCDC172
gene id: 89673:CCDC172
uniprot id: A0A7E6DX00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC172 family.
messages: Cytoplasm

89673:CALCR
gene id: 89673:CALCR
uniprot id: A0A6J2MQI0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Interacts with GPRASP2.
messages: Membrane

89673:CSF3
gene id: 89673:CSF3
uniprot id: A0A6J2MD58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IL-6 superfamily.
messages: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes.
messages: Monomer.

89673:PURG
gene id: 89673:PURG
uniprot id: A0A6J2MPZ2
uniprot id: A0A6J2MRT1
uniprot id: A0A6J2MW73
uniprot id: A0A7E6CKX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

89673:LOC114505981
gene id: 89673:LOC114505981
uniprot id: A0A7E6CGJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ATPase B chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion
messages: Mitochondrion inner membrane

89673:ACSL4
gene id: 89673:ACSL4
uniprot id: A0A6J2MGB1
uniprot id: A0A6J2MLU4
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

89673:SELENOO
gene id: 89673:SELENOO
uniprot id: A0A6J2NDU8
names: Similarity
messages: Belongs to the SELO family.

89673:LHCGR
gene id: 89673:LHCGR
uniprot id: A0A6J2M161
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

89673:DNTTIP2
gene id: 89673:DNTTIP2
uniprot id: A0A6J2LLX5
names: Subcellular Location Annotation
messages: nucleolus

89673:SEPTIN2
gene id: 89673:SEPTIN2
uniprot id: A0A6J2LBC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Filament-forming cytoskeletal GTPase.
messages: Midbody
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.
messages: cilium membrane
messages: flagellum
messages: spindle

89673:GRB2
gene id: 89673:GRB2
uniprot id: A0A6J2MFB6
names: Subcellular Location Annotation
messages: Endosome
messages: Golgi apparatus
messages: Nucleus

89673:CDC5L
gene id: 89673:CDC5L
uniprot id: A0A6J2LB67
names: Similarity
messages: Belongs to the CEF1 family.

89673:LOC118499104
gene id: 89673:LOC118499104
uniprot id: A0A7E6D737
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

89673:LOC114499085
gene id: 89673:LOC114499085
uniprot id: A0A6J2LU22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ATPAF1
gene id: 89673:ATPAF1
uniprot id: A0A6J2LPF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP11 family.
messages: Mitochondrion

89673:LOC114490424
gene id: 89673:LOC114490424
uniprot id: A0A6J2L1L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TOM1L2
gene id: 89673:TOM1L2
uniprot id: A0A6J2NC61
uniprot id: A0A6J2NC66
uniprot id: A0A6J2NC69
uniprot id: A0A6J2NDS4
uniprot id: A0A6J2NDS8
uniprot id: A0A6J2NE96
uniprot id: A0A6J2NEA1
uniprot id: A0A6J2NIX0
uniprot id: A0A6J2NJC7
uniprot id: A0A7E6EBN8
uniprot id: A0A7E6EBR8
uniprot id: A0A7E6ECE9
uniprot id: A0A7E6ECF9
uniprot id: A0A7E6ECS3
names: Similarity
messages: Belongs to the TOM1 family.

89673:BTK
gene id: 89673:BTK
uniprot id: A0A6J2ML47
uniprot id: A0A7E6D215
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

89673:PLXNA1
gene id: 89673:PLXNA1
uniprot id: A0A6J2MMV9
uniprot id: A0A7E6CE66
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:LOC114515183
gene id: 89673:LOC114515183
uniprot id: A0A6J2NEV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: myofibril

89673:DUSP13
gene id: 89673:DUSP13
uniprot id: A0A6J2LM10
uniprot id: A0A6J2LSF4
uniprot id: A0A7E6DTX1
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

89673:GPRIN1
gene id: 89673:GPRIN1
uniprot id: A0A7E6CTE9
names: Function
messages: May be involved in neurite outgrowth.

89673:NCK1
gene id: 89673:NCK1
uniprot id: A0A6J2M6V7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum

89673:VAMP4
gene id: 89673:VAMP4
uniprot id: A0A6J2N2I0
uniprot id: A0A7E6CV67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

89673:S100Z
gene id: 89673:S100Z
uniprot id: A0A6J2N6K5
names: Similarity
messages: Belongs to the S-100 family.

89673:LOC114496903
gene id: 89673:LOC114496903
uniprot id: A0A7E6DW32
names: Similarity
messages: Belongs to the SAP18 family.

89673:SPTLC2
gene id: 89673:SPTLC2
uniprot id: A0A6J2L604
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

89673:ANXA9
gene id: 89673:ANXA9
uniprot id: A0A6J2KW43
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

89673:LOC114508146
gene id: 89673:LOC114508146
uniprot id: A0A6J2MVT0
uniprot id: A0A7E6CIG6
names: Similarity
messages: Belongs to the leptin family.

89673:REEP4
gene id: 89673:REEP4
uniprot id: A0A6J2MBC3
uniprot id: A0A7E6EB74
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:NOP16
gene id: 89673:NOP16
uniprot id: A0A6J2MUS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP16 family.
messages: nucleolus

89673:ACOX3
gene id: 89673:ACOX3
uniprot id: A0A6J2KZY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

89673:LOC114500427
gene id: 89673:LOC114500427
uniprot id: A0A6J2M3W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:PPP1R12A
gene id: 89673:PPP1R12A
uniprot id: A0A6J2NE83
uniprot id: A0A6J2NEV9
uniprot id: A0A7E6D5L2
uniprot id: A0A7E6D5M9
uniprot id: A0A7E6D675
uniprot id: A0A7E6D8D3
names: Subcellular Location Annotation
names: Subunit
messages: PP1 comprises a catalytic subunit, and one or several targeting or regulatory subunits.
messages: stress fiber

89673:LOC114490164
gene id: 89673:LOC114490164
uniprot id: A0A6J2L2P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114511686
gene id: 89673:LOC114511686
uniprot id: A0A7E6D9V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenoprotein P family.
messages: Secreted

89673:LOC114504290
gene id: 89673:LOC114504290
uniprot id: A0A6J2MEV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:C9H20orf173
gene id: 89673:C9H20orf173
uniprot id: A0A6J2MMV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

89673:PARP11
gene id: 89673:PARP11
uniprot id: A0A6J2NGC4
uniprot id: A0A7E6D584
uniprot id: A0A7E6D5A0
uniprot id: A0A7E6D5E0
uniprot id: A0A7E6D850
names: Similarity
messages: Belongs to the ARTD/PARP family.

89673:LOC114513439
gene id: 89673:LOC114513439
uniprot id: A0A6J2N9S1
uniprot id: A0A7E6D6U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM198 family.
messages: Membrane

89673:MEF2A
gene id: 89673:MEF2A
uniprot id: A0A6J2KTS6
uniprot id: A0A6J2KVE9
uniprot id: A0A6J2KXN9
uniprot id: A0A7E6CPG7
uniprot id: A0A7E6CRY3
names: Subcellular Location Annotation
messages: Nucleus

89673:SLC39A5
gene id: 89673:SLC39A5
uniprot id: A0A6J2N8H5
names: Subcellular Location Annotation
messages: Membrane

89673:TMPRSS15
gene id: 89673:TMPRSS15
uniprot id: A0A6J2L001
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMBT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:ARID1A
gene id: 89673:ARID1A
uniprot id: A0A6J2LPX0
uniprot id: A0A6J2LS22
uniprot id: A0A6J2LV38
uniprot id: A0A6J2LVD5
names: Subcellular Location Annotation
messages: Nucleus

89673:MEGF11
gene id: 89673:MEGF11
uniprot id: A0A6J2L8X9
uniprot id: A0A6J2L9D0
uniprot id: A0A6J2LDG0
uniprot id: A0A7E6CE71
uniprot id: A0A7E6CGE9
uniprot id: A0A7E6CGF1
uniprot id: A0A7E6CGG4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:GPC5
gene id: 89673:GPC5
uniprot id: A0A6J2MWN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

89673:LOC118501112
gene id: 89673:LOC118501112
uniprot id: A0A7E6DXJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

89673:LOC118502267
gene id: 89673:LOC118502267
uniprot id: A0A7E6EFK7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

89673:ZC3H14
gene id: 89673:ZC3H14
uniprot id: A0A6J2L3I5
uniprot id: A0A6J2L468
uniprot id: A0A6J2L5U5
uniprot id: A0A6J2L5V0
uniprot id: A0A6J2L9I9
uniprot id: A0A7E6CPJ6
uniprot id: A0A7E6CPS1
uniprot id: A0A7E6CPU5
uniprot id: A0A7E6CRX6
uniprot id: A0A7E6CRZ6
uniprot id: A0A7E6CS00
uniprot id: A0A7E6CS33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZC3H14 family.
messages: Involved in poly(A) tail length control in neuronal cells. Binds the polyadenosine RNA oligonucleotides.
messages: Nucleus speckle

89673:TOMM20
gene id: 89673:TOMM20
uniprot id: A0A6J2N5N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

89673:GHRL
gene id: 89673:GHRL
uniprot id: A0A6J2M3N3
uniprot id: A0A7E6E549
uniprot id: A0A7E6E6N7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the motilin family.
messages: Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation.
messages: O-octanoylation is essential for ghrelin activity.
messages: Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility.
messages: Secreted

89673:ABLIM2
gene id: 89673:ABLIM2
uniprot id: A0A7E6D4T3
uniprot id: A0A7E6D4W7
uniprot id: A0A7E6D4Y1
uniprot id: A0A7E6D4Z2
uniprot id: A0A7E6D4Z6
uniprot id: A0A7E6D504
uniprot id: A0A7E6D508
uniprot id: A0A7E6D512
uniprot id: A0A7E6D517
uniprot id: A0A7E6D519
uniprot id: A0A7E6D521
uniprot id: A0A7E6D529
uniprot id: A0A7E6D5J1
uniprot id: A0A7E6D5J3
uniprot id: A0A7E6D5L1
names: Subcellular Location Annotation
messages: Cytoplasm

89673:USH1G
gene id: 89673:USH1G
uniprot id: A0A6J2MFQ8
names: Function
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

89673:PLD2
gene id: 89673:PLD2
uniprot id: A0A6J2NJ35
uniprot id: A0A7E6EDE0
names: Similarity
messages: Belongs to the phospholipase D family.

89673:MFSD14A
gene id: 89673:MFSD14A
uniprot id: A0A6J2KU91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

89673:LOC114506818
gene id: 89673:LOC114506818
uniprot id: A0A7E6CF00
names: Similarity
messages: Belongs to the cullin family.

89673:LOC114510804
gene id: 89673:LOC114510804
uniprot id: A0A6J2MZR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:DCLRE1B
gene id: 89673:DCLRE1B
uniprot id: A0A6J2KV26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

89673:LOC114513398
gene id: 89673:LOC114513398
uniprot id: A0A7E6D9E1
names: Similarity
messages: Belongs to the intermediate filament family.

89673:PPIF
gene id: 89673:PPIF
uniprot id: A0A6J2LM79
uniprot id: A0A7E6DTV9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

89673:LDB1
gene id: 89673:LDB1
uniprot id: A0A6J2LI82
uniprot id: A0A6J2LLY7
uniprot id: A0A6J2LMP7
uniprot id: A0A7E6DV33
names: Similarity
messages: Belongs to the LDB family.

89673:RGN
gene id: 89673:RGN
uniprot id: A0A6J2MIL8
uniprot id: A0A6J2MM17
uniprot id: A0A7E6CYT9
uniprot id: A0A7E6D1H4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMP-30/CGR1 family.
messages: Cytoplasm
messages: Monomer.

89673:JAKMIP3
gene id: 89673:JAKMIP3
uniprot id: A0A7E6DWM0
names: Similarity
messages: Belongs to the JAKMIP family.

89673:PGPEP1
gene id: 89673:PGPEP1
uniprot id: A0A6J2M7S5
uniprot id: A0A6J2MB77
uniprot id: A0A7E6EA05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

89673:FZD2
gene id: 89673:FZD2
uniprot id: A0A6J2MEV4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:PPP1R2C
gene id: 89673:PPP1R2C
uniprot id: A0A6J2MGP1
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 2 family.

89673:PPP1CC
gene id: 89673:PPP1CC
uniprot id: A0A6J2MUA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: nucleolus
messages: nucleoplasm

89673:TOR4A
gene id: 89673:TOR4A
uniprot id: A0A6J2MRX2
names: Similarity
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.

89673:PTPRF
gene id: 89673:PTPRF
uniprot id: A0A6J2LJD9
uniprot id: A0A6J2LKK1
uniprot id: A0A6J2LPX3
uniprot id: A0A7E6DRG4
uniprot id: A0A7E6DRG6
uniprot id: A0A7E6DRH1
uniprot id: A0A7E6DRH4
uniprot id: A0A7E6DRH8
uniprot id: A0A7E6DRI3
uniprot id: A0A7E6DS44
uniprot id: A0A7E6DS51
uniprot id: A0A7E6DS56
uniprot id: A0A7E6DS82
uniprot id: A0A7E6DS88
uniprot id: A0A7E6DS93
uniprot id: A0A7E6DSL5
uniprot id: A0A7E6DSM0
uniprot id: A0A7E6DSM5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.

89673:AK4
gene id: 89673:AK4
uniprot id: A0A6J2LRU8
uniprot id: A0A6J2LV40
uniprot id: A0A7E6DTK6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP/ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP/ATP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity.
messages: Mitochondrion matrix
messages: Monomer.

89673:B3GNT9
gene id: 89673:B3GNT9
uniprot id: A0A7E6CLS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

89673:RIN2
gene id: 89673:RIN2
uniprot id: A0A6J2MHB5
uniprot id: A0A7E6CEF1
uniprot id: A0A7E6CEK8
uniprot id: A0A7E6CEL2
uniprot id: A0A7E6CF44
uniprot id: A0A7E6CF49
names: Similarity
messages: Belongs to the RIN (Ras interaction/interference) family.

89673:GFOD2
gene id: 89673:GFOD2
uniprot id: A0A6J2KQV8
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

89673:CDT1
gene id: 89673:CDT1
uniprot id: A0A7E6CN27
names: Similarity
messages: Belongs to the Cdt1 family.

89673:CAPN12
gene id: 89673:CAPN12
uniprot id: A0A6J2N777
names: Similarity
messages: Belongs to the peptidase C2 family.

89673:PDGFRL
gene id: 89673:PDGFRL
uniprot id: A0A6J2MXD6
names: Subunit
messages: Forms a complex composed of PDGFRL, TNK2 and GRB2.

89673:NDUFA12
gene id: 89673:NDUFA12
uniprot id: A0A6J2NEX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA12 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

89673:LOC114501630
gene id: 89673:LOC114501630
uniprot id: A0A7E6E4M7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

89673:SLC2A1
gene id: 89673:SLC2A1
uniprot id: A0A6J2LKV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane
messages: Membrane
messages: Photoreceptor inner segment

89673:COMTD1
gene id: 89673:COMTD1
uniprot id: A0A6J2LSG5
uniprot id: A0A7E6DUV3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

89673:PFKL
gene id: 89673:PFKL
uniprot id: A0A6J2KZK7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114490248
gene id: 89673:LOC114490248
uniprot id: A0A6J2KZE1
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:DNM2
gene id: 89673:DNM2
uniprot id: A0A6J2M7I7
uniprot id: A0A6J2M8V1
uniprot id: A0A6J2M8V8
uniprot id: A0A6J2M9G5
uniprot id: A0A6J2MC87
uniprot id: A0A6J2MC91
uniprot id: A0A6J2MCU9
uniprot id: A0A7E6EA36
uniprot id: A0A7E6EAB8
uniprot id: A0A7E6EBB3
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

89673:POLD3
gene id: 89673:POLD3
uniprot id: A0A6J2LVL8
uniprot id: A0A7E6DZT5
uniprot id: A0A7E6E0A5
names: Subcellular Location Annotation
messages: Nucleus

89673:CDKN3
gene id: 89673:CDKN3
uniprot id: A0A6J2L1Q4
uniprot id: A0A7E6CGD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family.
messages: May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues.
messages: perinuclear region

89673:HOXD9
gene id: 89673:HOXD9
uniprot id: A0A6J2LJ65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

89673:SLC25A12
gene id: 89673:SLC25A12
uniprot id: A0A6J2LGS7
uniprot id: A0A6J2LJB4
uniprot id: A0A6J2LJB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

89673:TMEM38A
gene id: 89673:TMEM38A
uniprot id: A0A6J2MCG8
uniprot id: A0A7E6EBS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

89673:SLC39A10
gene id: 89673:SLC39A10
uniprot id: A0A6J2LBP5
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114509373
gene id: 89673:LOC114509373
uniprot id: A0A7E6DCA9
names: Subcellular Location Annotation
messages: Membrane

89673:NNAT
gene id: 89673:NNAT
uniprot id: A0A6J2MHE3
uniprot id: A0A6J2MJI2
uniprot id: A0A6J2MNB4
names: Similarity
messages: Belongs to the neuronatin family.

89673:NIBAN1
gene id: 89673:NIBAN1
uniprot id: A0A7E6CV02
uniprot id: A0A7E6CVI1
names: Similarity
messages: Belongs to the Niban family.

89673:KCNG4
gene id: 89673:KCNG4
uniprot id: A0A6J2KUQ7
uniprot id: A0A7E6CML4
names: Subcellular Location Annotation
messages: Membrane

89673:CTSS
gene id: 89673:CTSS
uniprot id: A0A6J2KUZ7
uniprot id: A0A7E6CVT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

89673:VTI1B
gene id: 89673:VTI1B
uniprot id: A0A6J2L6N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

89673:NFE2L1
gene id: 89673:NFE2L1
uniprot id: A0A6J2M931
uniprot id: A0A6J2M9M1
uniprot id: A0A6J2MCZ6
uniprot id: A0A6J2MD03
uniprot id: A0A7E6EEA5
uniprot id: A0A7E6EFA4
uniprot id: A0A7E6EFG3
names: Similarity
messages: Belongs to the bZIP family. CNC subfamily.

89673:LOC114495134
gene id: 89673:LOC114495134
uniprot id: A0A6J2LJX1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:GPR158
gene id: 89673:GPR158
uniprot id: A0A6J2L8M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

89673:LOC114510119
gene id: 89673:LOC114510119
uniprot id: A0A6J2MYG0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:FERMT2
gene id: 89673:FERMT2
uniprot id: A0A6J2L3P5
uniprot id: A0A6J2L6Y5
uniprot id: A0A7E6CG97
uniprot id: A0A7E6CGC9
uniprot id: A0A7E6CGD9
uniprot id: A0A7E6CGL5
names: Similarity
messages: Belongs to the kindlin family.

89673:MCRIP2
gene id: 89673:MCRIP2
uniprot id: A0A6J2N556
uniprot id: A0A7E6DCW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCRIP family.
messages: Nucleus
messages: Stress granule

89673:SRPRA
gene id: 89673:SRPRA
uniprot id: A0A6J2MZ45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:IDH3G
gene id: 89673:IDH3G
uniprot id: A0A6J2MHA4
uniprot id: A0A6J2MKJ8
uniprot id: A0A7E6D032
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

89673:OLFM1
gene id: 89673:OLFM1
uniprot id: A0A6J2MH70
uniprot id: A0A6J2MH77
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

89673:PAICS
gene id: 89673:PAICS
uniprot id: A0A6J2LAX2
names: Similarity
names: Subunit
messages: Homooctamer.
messages: In the C-terminal section; belongs to the AIR carboxylase family. Class II subfamily.
messages: In the N-terminal section; belongs to the SAICAR synthetase family.

89673:PRKCE
gene id: 89673:PRKCE
uniprot id: A0A6J2LUK9
uniprot id: A0A7E6DY45
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin-dependent signaling, by mediating angiotensin-2-induced activation of integrin beta-1 (ITGB1) in cardiac fibroblasts. Phosphorylates MARCKS, which phosphorylates and activates PTK2/FAK, leading to the spread of cardiomyocytes. Involved in the control of the directional transport of ITGB1 in mesenchymal cells by phosphorylating vimentin (VIM), an intermediate filament (IF) protein. In epithelial cells, associates with and phosphorylates keratin-8 (KRT8), which induces targeting of desmoplakin at desmosomes and regulates cell-cell contact. Phosphorylates IQGAP1, which binds to CDC42, mediating epithelial cell-cell detachment prior to migration.
messages: Cell membrane
messages: Cytoplasm
messages: Novel PKCs (PRKCD, PRKCE, PRKCH and PRKCQ) are calcium-insensitive, but activated by diacylglycerol (DAG) and phosphatidylserine.
messages: Nucleus
messages: cytoskeleton
messages: perinuclear region

89673:LOC114490323
gene id: 89673:LOC114490323
uniprot id: A0A6J2L376
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ADAMTS14
gene id: 89673:ADAMTS14
uniprot id: A0A6J2LL86
uniprot id: A0A7E6DU52
uniprot id: A0A7E6DU95
uniprot id: A0A7E6DU99
uniprot id: A0A7E6DUQ2
uniprot id: A0A7E6DV25
uniprot id: A0A7E6DVF7
uniprot id: A0A7E6DVG1
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

89673:BORCS7
gene id: 89673:BORCS7
uniprot id: A0A6J2LSR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS7 family.
messages: Lysosome membrane
messages: Membrane

89673:SHMT2
gene id: 89673:SHMT2
uniprot id: A0A6J2NDB1
uniprot id: A0A7E6D5V8
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

89673:LOC114497039
gene id: 89673:LOC114497039
uniprot id: A0A7E6DW01
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

89673:RAD51
gene id: 89673:RAD51
uniprot id: A0A6J2L4E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Nucleus
messages: Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR). Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Recruited to resolve stalled replication forks during replication stress. Also involved in interstrand cross-link repair.

89673:CCNJ
gene id: 89673:CCNJ
uniprot id: A0A6J2LHW0
uniprot id: A0A6J2LMT4
names: Similarity
messages: Belongs to the cyclin family.

89673:PFKFB4
gene id: 89673:PFKFB4
uniprot id: A0A6J2M3X0
uniprot id: A0A6J2M6N9
uniprot id: A0A7E6E4L0
uniprot id: A0A7E6E5J2
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

89673:EML1
gene id: 89673:EML1
uniprot id: A0A6J2L3L3
uniprot id: A0A6J2L491
uniprot id: A0A7E6CS43
uniprot id: A0A7E6CS44
names: Similarity
messages: Belongs to the WD repeat EMAP family.

89673:LOC114510755
gene id: 89673:LOC114510755
uniprot id: A0A6J2MZN4
names: Similarity
messages: Belongs to the MHC class I family.

89673:ATP5ME
gene id: 89673:ATP5ME
uniprot id: A0A6J2L226
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase e subunit family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

89673:KIF4A
gene id: 89673:KIF4A
uniprot id: A0A6J2ME43
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

89673:PDIA6
gene id: 89673:PDIA6
uniprot id: A0A6J2LUM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen
messages: Melanosome

89673:FMO2
gene id: 89673:FMO2
uniprot id: A0A6J2N8E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

89673:CMC2
gene id: 89673:CMC2
uniprot id: A0A6J2KSZ7
uniprot id: A0A7E6CMM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion

89673:TGFB2
gene id: 89673:TGFB2
uniprot id: A0A6J2N3X0
uniprot id: A0A6J2N5Q0
uniprot id: A0A7E6CYG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.
messages: extracellular matrix

89673:LOC114500611
gene id: 89673:LOC114500611
uniprot id: A0A7E6E0V1
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

89673:LOC114508218
gene id: 89673:LOC114508218
uniprot id: A0A6J2MVM5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:PPP1R12C
gene id: 89673:PPP1R12C
uniprot id: A0A6J2N2H6
names: Subcellular Location Annotation
names: Subunit
messages: PP1 comprises a catalytic subunit, and one or several targeting or regulatory subunits.
messages: stress fiber

89673:LOC114507616
gene id: 89673:LOC114507616
uniprot id: A0A6J2MTV1
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

89673:SNAPC3
gene id: 89673:SNAPC3
uniprot id: A0A6J2MNY8
uniprot id: A0A7E6DEN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNAPC3/SRD2 family.
messages: Nucleus
messages: Part of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC3 interacts with SNAPC1.
messages: Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.

89673:LOC114505596
gene id: 89673:LOC114505596
uniprot id: A0A6J2MIT0
uniprot id: A0A6J2MMU8
uniprot id: A0A7E6DC58
uniprot id: A0A7E6DD22
names: Similarity
messages: Belongs to the TIM16/PAM16 family.
messages: Belongs to the WD repeat coronin family.

89673:LOC114500354
gene id: 89673:LOC114500354
uniprot id: A0A6J2LYL1
uniprot id: A0A6J2M443
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:PKLR
gene id: 89673:PKLR
uniprot id: A0A6J2KV45
uniprot id: A0A6J2KWT7
uniprot id: A0A7E6CXY1
names: Similarity
messages: Belongs to the pyruvate kinase family.

89673:LOC114507636
gene id: 89673:LOC114507636
uniprot id: A0A6J2MPD1
uniprot id: A0A7E6DAB2
uniprot id: A0A7E6DBG2
uniprot id: A0A7E6DD47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTF2H2 family.
messages: Nucleus

89673:PDGFRB
gene id: 89673:PDGFRB
uniprot id: A0A7E6CTN7
uniprot id: A0A7E6CTX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Interacts with homodimeric PDGFB and PDGFD, and with heterodimers formed by PDGFA and PDGFB.
messages: Lysosome lumen
messages: Membrane
messages: Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells.
messages: Vesicle

89673:MAP3K13
gene id: 89673:MAP3K13
uniprot id: A0A6J2L1T4
names: Function
names: Similarity
messages: Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7.
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

89673:AMER2
gene id: 89673:AMER2
uniprot id: A0A6J2N7Z1
uniprot id: A0A6J2N9Q4
uniprot id: A0A7E6D7R4
names: Similarity
messages: Belongs to the Amer family.

89673:ATP1B1
gene id: 89673:ATP1B1
uniprot id: A0A6J2N2E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

89673:MICOS13
gene id: 89673:MICOS13
uniprot id: A0A6J2MDE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic13 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

89673:LOC114507421
gene id: 89673:LOC114507421
uniprot id: A0A7E6CL34
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

89673:KREMEN1
gene id: 89673:KREMEN1
uniprot id: A0A6J2N0M4
uniprot id: A0A7E6CU38
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6.

89673:TMEM244
gene id: 89673:TMEM244
uniprot id: A0A7E6DN54
uniprot id: A0A7E6DNL6
names: Subcellular Location Annotation
messages: Membrane

89673:FABP1
gene id: 89673:FABP1
uniprot id: A0A6J2M500
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport.
messages: Cytoplasm
messages: Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.

89673:SGO1
gene id: 89673:SGO1
uniprot id: A0A6J2M3B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

89673:LOC114499595
gene id: 89673:LOC114499595
uniprot id: A0A6J2LWJ1
names: Similarity
messages: Belongs to the CD225/Dispanin family.

89673:RPL4
gene id: 89673:RPL4
uniprot id: A0A6J2L823
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

89673:ETV5
gene id: 89673:ETV5
uniprot id: A0A6J2L3K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

89673:POLE
gene id: 89673:POLE
uniprot id: A0A6J2KVY8
uniprot id: A0A7E6CTK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: DNA polymerase II participates in chromosomal DNA replication.
messages: Nucleus

89673:HTR4
gene id: 89673:HTR4
uniprot id: A0A7E6CSH4
uniprot id: A0A7E6CSS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Endosome
messages: Membrane
messages: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.

89673:LOC114513675
gene id: 89673:LOC114513675
uniprot id: A0A7E6D8J2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

89673:ZADH2
gene id: 89673:ZADH2
uniprot id: A0A6J2ML94
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

89673:ZDHHC2
gene id: 89673:ZDHHC2
uniprot id: A0A6J2MX44
uniprot id: A0A7E6CKY2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

89673:LOC114507860
gene id: 89673:LOC114507860
uniprot id: A0A6J2MQA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TCP1
gene id: 89673:TCP1
uniprot id: A0A6J2LFR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: centrosome

89673:RICTOR
gene id: 89673:RICTOR
uniprot id: A0A6J2L2W4
uniprot id: A0A7E6D9W9
uniprot id: A0A7E6DA47
names: Similarity
messages: Belongs to the RICTOR family.

89673:GRAMD1A
gene id: 89673:GRAMD1A
uniprot id: A0A6J2MYJ7
uniprot id: A0A6J2N070
uniprot id: A0A6J2N4V7
uniprot id: A0A7E6CMU9
uniprot id: A0A7E6CMV4
uniprot id: A0A7E6CMV9
uniprot id: A0A7E6CMW3
uniprot id: A0A7E6CN04
uniprot id: A0A7E6CN07
uniprot id: A0A7E6CQ96
uniprot id: A0A7E6CQA1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:TCF7L1
gene id: 89673:TCF7L1
uniprot id: A0A6J2M0S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

89673:LOC114502617
gene id: 89673:LOC114502617
uniprot id: A0A6J2MBG5
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:KIF3C
gene id: 89673:KIF3C
uniprot id: A0A6J2LW34
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

89673:TCL1A
gene id: 89673:TCL1A
uniprot id: A0A6J2L332
names: Similarity
messages: Belongs to the TCL1 family.

89673:ZNF202
gene id: 89673:ZNF202
uniprot id: A0A6J2MWN7
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114491433
gene id: 89673:LOC114491433
uniprot id: A0A7E6DMI1
names: Similarity
messages: Belongs to the eukaryotic mitochondrial porin family.

89673:NUDT12
gene id: 89673:NUDT12
uniprot id: A0A6J2MFP5
uniprot id: A0A7E6DDD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Cytoplasmic granule
messages: Peroxisome

89673:KARS1
gene id: 89673:KARS1
uniprot id: A0A6J2KQ13
uniprot id: A0A6J2KQM9
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

89673:PDCL2
gene id: 89673:PDCL2
uniprot id: A0A6J2L8V4
names: Similarity
messages: Belongs to the phosducin family.

89673:LOC114490113
gene id: 89673:LOC114490113
uniprot id: A0A7E6CZH3
names: Subcellular Location Annotation
messages: Membrane

89673:HTR2B
gene id: 89673:HTR2B
uniprot id: A0A6J2LEC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: synaptosome

89673:LOC114498593
gene id: 89673:LOC114498593
uniprot id: A0A6J2LWN3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114504605
gene id: 89673:LOC114504605
uniprot id: A0A6J2MJI6
names: Similarity
messages: Belongs to the FAM47 family.

89673:CACUL1
gene id: 89673:CACUL1
uniprot id: A0A6J2LNT6
names: Similarity
messages: Belongs to the cullin family.

89673:TMC6
gene id: 89673:TMC6
uniprot id: A0A7E6EFB5
uniprot id: A0A7E6EFM3
uniprot id: A0A7E6EGJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

89673:TMEM70
gene id: 89673:TMEM70
uniprot id: A0A6J2M8V4
names: Similarity
messages: Belongs to the TMEM70 family.

89673:NKX1-1
gene id: 89673:NKX1-1
uniprot id: A0A6J2KVY7
names: Subcellular Location Annotation
messages: Nucleus

89673:SNW1
gene id: 89673:SNW1
uniprot id: A0A6J2L469
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNW family.
messages: Identified in the spliceosome C complex.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

89673:RRM1
gene id: 89673:RRM1
uniprot id: A0A6J2LT53
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

89673:ESD
gene id: 89673:ESD
uniprot id: A0A6J2MSV1
uniprot id: A0A7E6CLN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the esterase D family.
messages: Cytoplasmic vesicle
messages: Serine hydrolase involved in the detoxification of formaldehyde.

89673:NEURL2
gene id: 89673:NEURL2
uniprot id: A0A6J2MLE5
names: Subcellular Location Annotation
messages: Cytoplasm

89673:ANXA11
gene id: 89673:ANXA11
uniprot id: A0A6J2LMQ6
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

89673:LOC114496094
gene id: 89673:LOC114496094
uniprot id: A0A6J2LMZ7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Membrane

89673:CSMD2
gene id: 89673:CSMD2
uniprot id: A0A6J2LMQ9
uniprot id: A0A7E6DRS0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114503622
gene id: 89673:LOC114503622
uniprot id: A0A7E6EG37
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

89673:MPP2
gene id: 89673:MPP2
uniprot id: A0A6J2MC30
uniprot id: A0A6J2MH71
uniprot id: A0A7E6EFW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane

89673:CNFN
gene id: 89673:CNFN
uniprot id: A0A6J2N8B3
uniprot id: A0A7E6CPC7
names: Similarity
messages: Belongs to the cornifelin family.

89673:FAM83H
gene id: 89673:FAM83H
uniprot id: A0A6J2NHD8
uniprot id: A0A7E6E7A9
names: Similarity
messages: Belongs to the FAM83 family.

89673:LOC114513309
gene id: 89673:LOC114513309
uniprot id: A0A7E6D4P1
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

89673:NSG1
gene id: 89673:NSG1
uniprot id: A0A6J2LCF3
names: Similarity
messages: Belongs to the NSG family.

89673:MANEA
gene id: 89673:MANEA
uniprot id: A0A6J2LEK1
uniprot id: A0A7E6DN24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

89673:LAPTM4A
gene id: 89673:LAPTM4A
uniprot id: A0A6J2LZU1
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

89673:TRMT61A
gene id: 89673:TRMT61A
uniprot id: A0A6J2L5G7
uniprot id: A0A7E6CTI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
messages: Nucleus

89673:ACVR1C
gene id: 89673:ACVR1C
uniprot id: A0A6J2LI61
uniprot id: A0A7E6DK31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

89673:KIF15
gene id: 89673:KIF15
uniprot id: A0A6J2M4G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-12 subfamily.
messages: spindle

89673:GSTO2
gene id: 89673:GSTO2
uniprot id: A0A6J2LT10
names: Function
names: Similarity
messages: Belongs to the GST superfamily. Omega family.
messages: Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA).

89673:SRD5A2
gene id: 89673:SRD5A2
uniprot id: A0A6J2M1W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane
messages: Microsome membrane

89673:TMEM147
gene id: 89673:TMEM147
uniprot id: A0A7E6CPT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM147 family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane

89673:SLC9A9
gene id: 89673:SLC9A9
uniprot id: A0A6J2L0N0
uniprot id: A0A7E6D3H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Endosome membrane
messages: Recycling endosome membrane

89673:AGPAT4
gene id: 89673:AGPAT4
uniprot id: A0A6J2KYW4
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

89673:LOC114509210
gene id: 89673:LOC114509210
uniprot id: A0A6J2MZJ8
uniprot id: A0A7E6DH52
names: Similarity
messages: Belongs to the ficolin lectin family.

89673:PGBD1
gene id: 89673:PGBD1
uniprot id: A0A7E6CW17
names: Subcellular Location Annotation
messages: Nucleus

89673:MSH6
gene id: 89673:MSH6
uniprot id: A0A6J2LR95
uniprot id: A0A7E6DXR3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).

89673:LOC114494322
gene id: 89673:LOC114494322
uniprot id: A0A6J2LHF0
names: Similarity
messages: Belongs to the cytochrome P450 family.

89673:PTMA
gene id: 89673:PTMA
uniprot id: A0A6J2LBI0
uniprot id: A0A6J2LCI9
names: Similarity
messages: Belongs to the pro/parathymosin family.

89673:PPDPFL
gene id: 89673:PPDPFL
uniprot id: A0A6J2M8Z3
names: Similarity
messages: Belongs to the PPDPF family.

89673:TRPM2
gene id: 89673:TRPM2
uniprot id: A0A6J2L5S5
uniprot id: A0A7E6D281
uniprot id: A0A7E6D2Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. TRPM2 sub-subfamily.
messages: Cell membrane
messages: Membrane

89673:RALY
gene id: 89673:RALY
uniprot id: A0A6J2MI25
uniprot id: A0A6J2MI31
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

89673:PDIK1L
gene id: 89673:PDIK1L
uniprot id: A0A6J2LIX9
uniprot id: A0A6J2LMM3
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:LOC114494739
gene id: 89673:LOC114494739
uniprot id: A0A7E6DAH0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:CHRNA10
gene id: 89673:CHRNA10
uniprot id: A0A6J2LXX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

89673:KIF5B
gene id: 89673:KIF5B
uniprot id: A0A7E6DX15
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

89673:CSF1R
gene id: 89673:CSF1R
uniprot id: A0A6J2N0N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

89673:CACNG3
gene id: 89673:CACNG3
uniprot id: A0A6J2MMH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane

89673:EVC
gene id: 89673:EVC
uniprot id: A0A6J2L606
uniprot id: A0A7E6D8H4
names: Subcellular Location Annotation
messages: Membrane
messages: cilium basal body
messages: cilium membrane

89673:LOC114502413
gene id: 89673:LOC114502413
uniprot id: A0A7E6E999
names: Similarity
messages: Belongs to the GroES chaperonin family.

89673:SLC35E3
gene id: 89673:SLC35E3
uniprot id: A0A6J2NGH7
names: Subcellular Location Annotation
messages: Membrane

89673:SLC25A17
gene id: 89673:SLC25A17
uniprot id: A0A6J2NAZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

89673:SLC27A3
gene id: 89673:SLC27A3
uniprot id: A0A6J2KTH0
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

89673:KCNE1
gene id: 89673:KCNE1
uniprot id: A0A6J2KX32
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the potassium channel KCNE family.
messages: Cell membrane
messages: Membrane

89673:LOC114499470
gene id: 89673:LOC114499470
uniprot id: A0A7E6DY94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

89673:LOC114503707
gene id: 89673:LOC114503707
uniprot id: A0A6J2MFU3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114505279
gene id: 89673:LOC114505279
uniprot id: A0A7E6D2A6
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

89673:SFRP2
gene id: 89673:SFRP2
uniprot id: A0A6J2MDS6
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:ESRRG
gene id: 89673:ESRRG
uniprot id: A0A6J2NAH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

89673:PRRT2
gene id: 89673:PRRT2
uniprot id: A0A6J2L2M4
uniprot id: A0A7E6DDR5
names: Similarity
messages: Belongs to the CD225/Dispanin family.

89673:LOC114504152
gene id: 89673:LOC114504152
uniprot id: A0A6J2MI33
names: Similarity
messages: Belongs to the peptidase S14 family.

89673:LOC114500365
gene id: 89673:LOC114500365
uniprot id: A0A6J2LZT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:DGCR6L
gene id: 89673:DGCR6L
uniprot id: A0A6J2MXI9
uniprot id: A0A7E6CU29
uniprot id: A0A7E6CUL7
uniprot id: A0A7E6CUT3
names: Similarity
messages: Belongs to the gonadal family.

89673:LOC114489411
gene id: 89673:LOC114489411
uniprot id: A0A6J2L0Q6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:DPYSL4
gene id: 89673:DPYSL4
uniprot id: A0A6J2LQ54
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

89673:SLC30A6
gene id: 89673:SLC30A6
uniprot id: A0A6J2M0P7
uniprot id: A0A6J2M449
uniprot id: A0A7E6DY90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

89673:RNF20
gene id: 89673:RNF20
uniprot id: A0A6J2LLQ4
uniprot id: A0A6J2LPF4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BRE1 family.
messages: Component of the RNF20/40 complex (also known as BRE1 complex) probably composed of 2 copies of RNF20/BRE1A and 2 copies of RNF40/BRE1B. Interacts with UBE2E1/UBCH6.
messages: Nucleus

89673:LOC114510242
gene id: 89673:LOC114510242
uniprot id: A0A6J2N397
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:BLOC1S6
gene id: 89673:BLOC1S6
uniprot id: A0A6J2L9Y3
uniprot id: A0A7E6EC15
uniprot id: A0A7E6EC30
uniprot id: A0A7E6ECX9
uniprot id: A0A7E6ED61
uniprot id: A0A7E6ED66
names: Function
names: Similarity
messages: Belongs to the BLOC1S6 family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particularly in the vesicle-docking and fusion process.

89673:ADPRHL1
gene id: 89673:ADPRHL1
uniprot id: A0A6J2MR10
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

89673:ITPA
gene id: 89673:ITPA
uniprot id: A0A6J2MPU6
uniprot id: A0A7E6CEV4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Cytoplasm
messages: Homodimer.
messages: Pyrophosphatase that hydrolyzes the non-canonical purine (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.

89673:TNFRSF9
gene id: 89673:TNFRSF9
uniprot id: A0A7E6DP96
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:MZT1
gene id: 89673:MZT1
uniprot id: A0A6J2MRV6
uniprot id: A0A7E6CJU9
names: Function
names: Similarity
messages: Belongs to the MOZART1 family.
messages: Required for gamma-tubulin complex recruitment to the centrosome.

89673:HBEGF
gene id: 89673:HBEGF
uniprot id: A0A6J2N1W6
uniprot id: A0A7E6CS35
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114494311
gene id: 89673:LOC114494311
uniprot id: A0A7E6DNC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

89673:APOC3
gene id: 89673:APOC3
uniprot id: A0A7E6E3I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apolipoprotein C3 family.
messages: Secreted

89673:SMAD9
gene id: 89673:SMAD9
uniprot id: A0A6J2MS69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

89673:CCDC130
gene id: 89673:CCDC130
uniprot id: A0A6J2MC55
names: Similarity
messages: Belongs to the CWC16 family.

89673:GLB1L
gene id: 89673:GLB1L
uniprot id: A0A6J2LAG4
uniprot id: A0A6J2LG55
uniprot id: A0A7E6DI48
uniprot id: A0A7E6DI91
uniprot id: A0A7E6DID6
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

89673:CA14
gene id: 89673:CA14
uniprot id: A0A6J2KUD9
uniprot id: A0A7E6CW75
uniprot id: A0A7E6CWN9
uniprot id: A0A7E6CYX3
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

89673:CENPK
gene id: 89673:CENPK
uniprot id: A0A6J2MH61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-K/MCM22 family.
messages: Nucleus
messages: centromere

89673:TEKT3
gene id: 89673:TEKT3
uniprot id: A0A6J2NCN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

89673:LOC114496999
gene id: 89673:LOC114496999
uniprot id: A0A7E6DXD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

89673:ARL14
gene id: 89673:ARL14
uniprot id: A0A7E6D2J5
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

89673:S1PR1
gene id: 89673:S1PR1
uniprot id: A0A6J2L094
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:NRN1L
gene id: 89673:NRN1L
uniprot id: A0A6J2KRH5
names: Similarity
messages: Belongs to the neuritin family.

89673:DDX52
gene id: 89673:DDX52
uniprot id: A0A6J2MAV6
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

89673:MFSD8
gene id: 89673:MFSD8
uniprot id: A0A6J2MD15
uniprot id: A0A7E6E8L6
uniprot id: A0A7E6E8T0
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114497606
gene id: 89673:LOC114497606
uniprot id: A0A6J2LTN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCP1 family.
messages: May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ).
messages: Nucleus
messages: spindle pole

89673:ACKR2
gene id: 89673:ACKR2
uniprot id: A0A6J2M844
names: Subcellular Location Annotation
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

89673:MCM2
gene id: 89673:MCM2
uniprot id: A0A6J2MPD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Chromosome
messages: Nucleus

89673:LOC114513506
gene id: 89673:LOC114513506
uniprot id: A0A6J2N7Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

89673:PDC
gene id: 89673:PDC
uniprot id: A0A6J2N953
names: Similarity
messages: Belongs to the phosducin family.

89673:COPS8
gene id: 89673:COPS8
uniprot id: A0A6J2LJH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN8 family.
messages: Cytoplasm
messages: Nucleus

89673:GTF2H1
gene id: 89673:GTF2H1
uniprot id: A0A7E6E1S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB1 family.
messages: Nucleus

89673:PDE3B
gene id: 89673:PDE3B
uniprot id: A0A6J2LW64
uniprot id: A0A7E6E1N5
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

89673:EHD2
gene id: 89673:EHD2
uniprot id: A0A6J2N1A0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

89673:RIDA
gene id: 89673:RIDA
uniprot id: A0A6J2NI65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RutC family.
messages: Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase.
messages: Peroxisome

89673:MSI1
gene id: 89673:MSI1
uniprot id: A0A6J2MVU6
uniprot id: A0A6J2MXH8
uniprot id: A0A6J2N210
uniprot id: A0A7E6CTY3
uniprot id: A0A7E6CWR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Musashi family.
messages: Cytoplasm

89673:KIF7
gene id: 89673:KIF7
uniprot id: A0A7E6CMP8
uniprot id: A0A7E6CMP9
uniprot id: A0A7E6CMU7
uniprot id: A0A7E6CQ50
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

89673:HOXC6
gene id: 89673:HOXC6
uniprot id: A0A6J2N9V3
uniprot id: A0A7E6D6D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

89673:INTS14
gene id: 89673:INTS14
uniprot id: A0A6J2L917
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INTS14 family.
messages: Nucleus
messages: Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.

89673:MAP2K5
gene id: 89673:MAP2K5
uniprot id: A0A6J2L3G1
uniprot id: A0A6J2L5D5
uniprot id: A0A7E6CEL9
uniprot id: A0A7E6CEM6
uniprot id: A0A7E6CEM7
uniprot id: A0A7E6CF61
uniprot id: A0A7E6CFA2
uniprot id: A0A7E6CGQ0
uniprot id: A0A7E6CGQ5
uniprot id: A0A7E6CGS5
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:LOC114498004
gene id: 89673:LOC114498004
uniprot id: A0A6J2LPZ1
uniprot id: A0A7E6DR67
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114502361
gene id: 89673:LOC114502361
uniprot id: A0A6J2M9R1
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.

89673:LOC114499900
gene id: 89673:LOC114499900
uniprot id: A0A6J2LWW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:PRICKLE3
gene id: 89673:PRICKLE3
uniprot id: A0A6J2MFD5
uniprot id: A0A7E6D1Q0
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

89673:ADGRL1
gene id: 89673:ADGRL1
uniprot id: A0A6J2M9C4
uniprot id: A0A6J2MC52
uniprot id: A0A7E6E9D3
uniprot id: A0A7E6EA60
uniprot id: A0A7E6EAE9
names: Subcellular Location Annotation
messages: Membrane

89673:DYDC2
gene id: 89673:DYDC2
uniprot id: A0A6J2LQN6
uniprot id: A0A7E6DTU4
uniprot id: A0A7E6DUG0
uniprot id: A0A7E6DV43
names: Similarity
messages: Belongs to the dpy-30 family.

89673:LOC114497263
gene id: 89673:LOC114497263
uniprot id: A0A7E6DTC4
names: Similarity
messages: Belongs to the SGT1 family.

89673:SMIM7
gene id: 89673:SMIM7
uniprot id: A0A6J2MCR5
names: Similarity
messages: Belongs to the SMIM7 family.

89673:LOC114501000
gene id: 89673:LOC114501000
uniprot id: A0A6J2M2N1
uniprot id: A0A7E6E210
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:MYOZ1
gene id: 89673:MYOZ1
uniprot id: A0A6J2LR55
names: Similarity
messages: Belongs to the myozenin family.

89673:LOC114492382
gene id: 89673:LOC114492382
uniprot id: A0A7E6CTC5
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114503706
gene id: 89673:LOC114503706
uniprot id: A0A6J2MCX9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114491003
gene id: 89673:LOC114491003
uniprot id: A0A6J2KZW1
names: Subcellular Location Annotation
messages: Membrane

89673:MPZ
gene id: 89673:MPZ
uniprot id: A0A6J2KWX4
uniprot id: A0A7E6CW65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the myelin P0 protein family.
messages: Cell membrane
messages: Homodimer and homotetramer.
messages: Is an adhesion molecule necessary for normal myelination in the peripheral nervous system. It mediates adhesion between adjacent myelin wraps and ultimately drives myelin compaction.
messages: Membrane

89673:LOC114499962
gene id: 89673:LOC114499962
uniprot id: A0A6J2LY85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TSPAN17
gene id: 89673:TSPAN17
uniprot id: A0A6J2MZY7
uniprot id: A0A7E6CRW4
uniprot id: A0A7E6CUI5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:LOC114503290
gene id: 89673:LOC114503290
uniprot id: A0A7E6EFF6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

89673:TBXA2R
gene id: 89673:TBXA2R
uniprot id: A0A6J2M9V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:SLC13A5
gene id: 89673:SLC13A5
uniprot id: A0A6J2NE80
uniprot id: A0A6J2NEN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

89673:DDX51
gene id: 89673:DDX51
uniprot id: A0A7E6CTD7
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

89673:RRAGA
gene id: 89673:RRAGA
uniprot id: A0A6J2LSC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

89673:RPL26
gene id: 89673:RPL26
uniprot id: A0A6J2NCW9
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

89673:AMER1
gene id: 89673:AMER1
uniprot id: A0A6J2MG89
names: Similarity
messages: Belongs to the Amer family.

89673:PTGS1
gene id: 89673:PTGS1
uniprot id: A0A6J2MS61
names: Caution
names: Similarity
messages: Belongs to the prostaglandin G/H synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:GABRR1
gene id: 89673:GABRR1
uniprot id: A0A6J2LEE4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Interacts with SQSTM1.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

89673:TMX2
gene id: 89673:TMX2
uniprot id: A0A6J2LXG1
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum and mitochondria-associated protein that probably functions as a regulator of cellular redox state and thereby regulates protein post-translational modification, protein folding and mitochondrial activity. Indirectly regulates neuronal proliferation, migration, and organization in the developing brain.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

89673:CRLF1
gene id: 89673:CRLF1
uniprot id: A0A6J2MAT3
uniprot id: A0A7E6EB15
uniprot id: A0A7E6EBP0
names: Subcellular Location Annotation
messages: Membrane

89673:SCGB1C1
gene id: 89673:SCGB1C1
uniprot id: A0A6J2M2L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the secretoglobin family.
messages: Secreted

89673:PLRG1
gene id: 89673:PLRG1
uniprot id: A0A6J2M7P1
uniprot id: A0A6J2M916
names: Similarity
messages: Belongs to the WD repeat PRL1/PRL2 family.

89673:ADAMTS19
gene id: 89673:ADAMTS19
uniprot id: A0A6J2MY96
uniprot id: A0A7E6CUU5
uniprot id: A0A7E6CVL2
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

89673:LOC114509078
gene id: 89673:LOC114509078
uniprot id: A0A7E6CVL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

89673:ITGAX
gene id: 89673:ITGAX
uniprot id: A0A7E6D9N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

89673:LOC114507719
gene id: 89673:LOC114507719
uniprot id: A0A6J2MPQ7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be a regulator of keratinocyte proliferation or differentiation.
messages: Nucleus

89673:TMEFF2
gene id: 89673:TMEFF2
uniprot id: A0A6J2LF62
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:SETD7
gene id: 89673:SETD7
uniprot id: A0A6J2MBU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET7 subfamily.
messages: Chromosome
messages: Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes.
messages: Nucleus

89673:HEBP2
gene id: 89673:HEBP2
uniprot id: A0A6J2LI56
names: Similarity
messages: Belongs to the HEBP family.

89673:LOC114496495
gene id: 89673:LOC114496495
uniprot id: A0A6J2LP37
names: Similarity
messages: Belongs to the EXO5 family.

89673:THBS3
gene id: 89673:THBS3
uniprot id: A0A6J2L085
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:ADAM29
gene id: 89673:ADAM29
uniprot id: A0A6J2MG37
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:SMAD3
gene id: 89673:SMAD3
uniprot id: A0A6J2L502
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

89673:GAB1
gene id: 89673:GAB1
uniprot id: A0A6J2MDY5
uniprot id: A0A7E6E814
uniprot id: A0A7E6E9J6
uniprot id: A0A7E6E9X0
names: Similarity
messages: Belongs to the GAB family.

89673:ANAPC10
gene id: 89673:ANAPC10
uniprot id: A0A6J2MCW3
names: Function
names: Similarity
messages: Belongs to the APC10 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.

89673:ST3GAL6
gene id: 89673:ST3GAL6
uniprot id: A0A6J2KXX2
uniprot id: A0A7E6D3Q3
uniprot id: A0A7E6D4F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

89673:EN2
gene id: 89673:EN2
uniprot id: A0A6J2MQK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Engrailed homeobox family.
messages: Nucleus

89673:LOC114510838
gene id: 89673:LOC114510838
uniprot id: A0A7E6CRB2
names: Similarity
messages: Belongs to the MHC class I family.

89673:LSM1
gene id: 89673:LSM1
uniprot id: A0A6J2L7P4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Cytoplasm
messages: Interacts with SLBP; interaction with SLBP occurs when histone mRNA is being rapidly degraded during the S phase. LSm subunits form a heteromer with a donut shape.
messages: P-body
messages: Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation.

89673:BRI3
gene id: 89673:BRI3
uniprot id: A0A6J2MWF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRI3 family.
messages: Membrane
messages: perinuclear region

89673:TMEM88B
gene id: 89673:TMEM88B
uniprot id: A0A6J2LQZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM88 family.
messages: Membrane

89673:DERL3
gene id: 89673:DERL3
uniprot id: A0A6J2MVV6
uniprot id: A0A6J2N0F7
uniprot id: A0A6J2N114
uniprot id: A0A7E6CT67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:LOC114499766
gene id: 89673:LOC114499766
uniprot id: A0A6J2M1C7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aldolase class II family. Adducin subfamily.
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death.
messages: Cytoplasm
messages: Homotetramer. Interacts with APAF1. May interact with CASP1.

89673:HSFX3
gene id: 89673:HSFX3
uniprot id: A0A7E6CZU0
names: Subcellular Location Annotation
messages: Nucleus

89673:ACAD8
gene id: 89673:ACAD8
uniprot id: A0A6J2MVV5
uniprot id: A0A7E6CTS3
uniprot id: A0A7E6CTT8
uniprot id: A0A7E6CUA0
uniprot id: A0A7E6CUI7
uniprot id: A0A7E6CWL5
uniprot id: A0A7E6CWM0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

89673:LOC118498911
gene id: 89673:LOC118498911
uniprot id: A0A7E6D516
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

89673:PLPP1
gene id: 89673:PLPP1
uniprot id: A0A6J2M6N3
uniprot id: A0A7E6DA05
uniprot id: A0A7E6DAQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

89673:TCTEX1D4
gene id: 89673:TCTEX1D4
uniprot id: A0A6J2LLS6
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

89673:SLC7A8
gene id: 89673:SLC7A8
uniprot id: A0A6J2L4S0
uniprot id: A0A7E6E444
uniprot id: A0A7E6E555
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Cell membrane
messages: Membrane

89673:BRK1
gene id: 89673:BRK1
uniprot id: A0A6J2M3D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRK1 family.
messages: cytoskeleton

89673:C5H1orf174
gene id: 89673:C5H1orf174
uniprot id: A0A6J2LRD5
uniprot id: A0A7E6DQ51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0688 family.
messages: Nucleus

89673:SPRING1
gene id: 89673:SPRING1
uniprot id: A0A6J2MWI3
uniprot id: A0A6J2MWJ4
uniprot id: A0A7E6CUH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPRING family.
messages: Golgi apparatus membrane
messages: Membrane

89673:ATG5
gene id: 89673:ATG5
uniprot id: A0A6J2LC46
uniprot id: A0A7E6DMP8
uniprot id: A0A7E6DNA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG5 family.
messages: Conjugated with ATG12.
messages: Involved in autophagic vesicle formation.
messages: Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control after oxidative damage, and in subsequent cellular longevity. Plays a critical role in multiple aspects of lymphocyte development and is essential for both B and T lymphocyte survival and proliferation. Required for optimal processing and presentation of antigens for MHC II. Involved in the maintenance of axon morphology and membrane structures, as well as in normal adipocyte differentiation. Promotes primary ciliogenesis through removal of OFD1 from centriolar satellites and degradation of IFT20 via the autophagic pathway.
messages: May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. Plays a crucial role in IFN-gamma-induced autophagic cell death by interacting with FADD.
messages: Preautophagosomal structure membrane

89673:ACTN2
gene id: 89673:ACTN2
uniprot id: A0A6J2N5H4
names: Similarity
messages: Belongs to the alpha-actinin family.

89673:LOC114499105
gene id: 89673:LOC114499105
uniprot id: A0A6J2LSX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:EGR3
gene id: 89673:EGR3
uniprot id: A0A6J2MCK9
uniprot id: A0A6J2MER6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus

89673:SLC11A2
gene id: 89673:SLC11A2
uniprot id: A0A6J2N9X7
uniprot id: A0A6J2NEN9
uniprot id: A0A6J2NFD0
uniprot id: A0A7E6D6M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Macrophage-specific antiporter that fluxes metal ions in either direction against a proton gradient. Localized to late endosomal lysosomal membranes, delivers bivalent cations from the cytosol into these acidic compartments where they may directly affect antimicrobial activity. Involved in iron metabolism and host natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis of its protective enzymes.

89673:PLXND1
gene id: 89673:PLXND1
uniprot id: A0A6J2M6D1
names: Caution
names: Similarity
messages: Belongs to the plexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114489482
gene id: 89673:LOC114489482
uniprot id: A0A7E6CY48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

89673:PELP1
gene id: 89673:PELP1
uniprot id: A0A6J2NIV8
uniprot id: A0A7E6ECF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RIX1/PELP1 family.
messages: Cytoplasm
messages: Nucleus

89673:LOC114499116
gene id: 89673:LOC114499116
uniprot id: A0A7E6E2Y9
names: Similarity
messages: Belongs to the MS4A family.

89673:LOC118497678
gene id: 89673:LOC118497678
uniprot id: A0A7E6CRM0
names: Subcellular Location Annotation
messages: Membrane

89673:DCAF13
gene id: 89673:DCAF13
uniprot id: A0A6J2NCW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DCAF13/WDSOF1 family.
messages: nucleolus

89673:LOC114490355
gene id: 89673:LOC114490355
uniprot id: A0A6J2KXH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

89673:PRDX1
gene id: 89673:PRDX1
uniprot id: A0A6J2LKI2
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

89673:CLIC2
gene id: 89673:CLIC2
uniprot id: A0A6J2MGE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Membrane

89673:TULP1
gene id: 89673:TULP1
uniprot id: A0A6J2LG89
uniprot id: A0A7E6DL85
uniprot id: A0A7E6DLM2
uniprot id: A0A7E6DLP8
uniprot id: A0A7E6DLZ6
names: Similarity
messages: Belongs to the TUB family.

89673:NDRG4
gene id: 89673:NDRG4
uniprot id: A0A6J2KPY0
uniprot id: A0A6J2KQJ9
uniprot id: A0A6J2KQK4
uniprot id: A0A6J2KS79
uniprot id: A0A6J2KTW2
uniprot id: A0A6J2KW40
names: Similarity
messages: Belongs to the NDRG family.

89673:PWP2
gene id: 89673:PWP2
uniprot id: A0A6J2L038
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PWP2 family.
messages: nucleolus

89673:LOC114508228
gene id: 89673:LOC114508228
uniprot id: A0A6J2MPD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TIMM13
gene id: 89673:TIMM13
uniprot id: A0A6J2M8F4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

89673:ATP5F1D
gene id: 89673:ATP5F1D
uniprot id: A0A6J2MEE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase epsilon chain family.
messages: Mitochondrion inner membrane

89673:PNOC
gene id: 89673:PNOC
uniprot id: A0A6J2ME69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Secreted

89673:PFKFB3
gene id: 89673:PFKFB3
uniprot id: A0A6J2L3E5
uniprot id: A0A6J2L426
uniprot id: A0A6J2L5R0
uniprot id: A0A6J2L5R3
uniprot id: A0A6J2L800
uniprot id: A0A7E6DMG2
uniprot id: A0A7E6DMG4
uniprot id: A0A7E6DMX6
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

89673:INSR
gene id: 89673:INSR
uniprot id: A0A6J2MZ70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

89673:NINJ2
gene id: 89673:NINJ2
uniprot id: A0A6J2NGG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ninjurin family.
messages: Membrane

89673:NXPH1
gene id: 89673:NXPH1
uniprot id: A0A6J2MMU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

89673:KATNA1
gene id: 89673:KATNA1
uniprot id: A0A6J2LEM8
names: Activity Regulation
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.
messages: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit. Interacts with ASPM; the katanin complex formation KATNA1:KATNB1 is required for the association of ASPM. Interacts with dynein and NDEL1. Associates with the E3 ligase complex containing DYRK2, EDD/UBR5, DDB1 and DCAF1 proteins (EDVP complex). Interacts with KLHL42 (via the kelch domains). Interacts with CUL3; the interaction is enhanced by KLHL42. Interacts with KATNB1 and KATNBL1. Interacts with CAMSAP2 and CAMSAP3; leading to regulate the length of CAMSAP-decorated microtubule stretches.
messages: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.
messages: Cytoplasm
messages: Midbody
messages: Phosphorylation by DYRK2 triggers ubiquitination and subsequent degradation.
messages: The N-terminus is sufficient for interaction with microtubules, although high affinity binding to microtubules also requires an intact C-terminal domain and ATP, which promotes oligomerization.
messages: Ubiquitinated by the BCR(KLHL42) E3 ubiquitin ligase complex, leading to its proteasomal degradation. Ubiquitinated by the EDVP E3 ligase complex and subsequently targeted for proteasomal degradation.
messages: centrosome
messages: spindle
messages: spindle pole

89673:LHX8
gene id: 89673:LHX8
uniprot id: A0A6J2LMT7
names: Subcellular Location Annotation
messages: Nucleus

89673:RPS19BP1
gene id: 89673:RPS19BP1
uniprot id: A0A6J2NA76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AROS family.
messages: nucleolus

89673:LOC114490327
gene id: 89673:LOC114490327
uniprot id: A0A6J2KZQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114506582
gene id: 89673:LOC114506582
uniprot id: A0A7E6CIG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin basic protein family.
messages: Myelin membrane

89673:WASHC3
gene id: 89673:WASHC3
uniprot id: A0A6J2NBI0
names: Similarity
messages: Belongs to the CCDC53 family.

89673:TRIO
gene id: 89673:TRIO
uniprot id: A0A6J2M057
uniprot id: A0A7E6D9Z9
uniprot id: A0A7E6DA36
uniprot id: A0A7E6DAB1
uniprot id: A0A7E6DB15
uniprot id: A0A7E6DCX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cytoplasm

89673:ACTG2
gene id: 89673:ACTG2
uniprot id: A0A6J2LX38
names: Similarity
messages: Belongs to the actin family.

89673:ICOS
gene id: 89673:ICOS
uniprot id: A0A6J2LGX0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes.
messages: Homodimer; disulfide-linked.
messages: Membrane

89673:LOC114490339
gene id: 89673:LOC114490339
uniprot id: A0A6J2L395
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:PFN4
gene id: 89673:PFN4
uniprot id: A0A6J2M649
uniprot id: A0A7E6DY03
names: Similarity
messages: Belongs to the profilin family.

89673:CX3CL1
gene id: 89673:CX3CL1
uniprot id: A0A6J2KX16
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.

89673:HOOK1
gene id: 89673:HOOK1
uniprot id: A0A6J2LI71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hook family.
messages: cytoskeleton

89673:RAF1
gene id: 89673:RAF1
uniprot id: A0A6J2M874
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

89673:SGMS2
gene id: 89673:SGMS2
uniprot id: A0A6J2LCU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

89673:GREM1
gene id: 89673:GREM1
uniprot id: A0A7E6E6R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

89673:AK6
gene id: 89673:AK6
uniprot id: A0A6J2L3B3
uniprot id: A0A7E6DAN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation.
messages: Cajal body
messages: Monomer and homodimer. Interacts with COIL (via C-terminus).
messages: nucleoplasm

89673:SGK3
gene id: 89673:SGK3
uniprot id: A0A6J2NBA8
uniprot id: A0A6J2NCZ5
uniprot id: A0A6J2NIQ3
uniprot id: A0A7E6E6Q1
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

89673:F3
gene id: 89673:F3
uniprot id: A0A6J2LP75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tissue factor family.
messages: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
messages: Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII.

89673:LOC114508980
gene id: 89673:LOC114508980
uniprot id: A0A6J2MRV8
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:CCDC65
gene id: 89673:CCDC65
uniprot id: A0A6J2N9D2
names: Subcellular Location Annotation
messages: flagellum axoneme

89673:SLC30A1
gene id: 89673:SLC30A1
uniprot id: A0A6J2N8X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

89673:LOC114508265
gene id: 89673:LOC114508265
uniprot id: A0A6J2MW28
names: Similarity
messages: Belongs to the TDD superfamily. DTWD2 family.

89673:EXOC7
gene id: 89673:EXOC7
uniprot id: A0A6J2M5H2
uniprot id: A0A6J2M5H7
uniprot id: A0A6J2M6Z8
uniprot id: A0A6J2M702
uniprot id: A0A6J2M7F0
uniprot id: A0A6J2MAB7
uniprot id: A0A6J2MAW1
uniprot id: A0A7E6EEM7
names: Function
names: Similarity
messages: Belongs to the EXO70 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

89673:SYBU
gene id: 89673:SYBU
uniprot id: A0A6J2NB35
uniprot id: A0A6J2NCS2
uniprot id: A0A6J2NHZ0
uniprot id: A0A7E6E6P4
uniprot id: A0A7E6E6P9
uniprot id: A0A7E6E7J3
uniprot id: A0A7E6E860
uniprot id: A0A7E6E8I4
names: Subcellular Location Annotation
messages: Membrane

89673:BARHL1
gene id: 89673:BARHL1
uniprot id: A0A6J2L9N0
names: Subcellular Location Annotation
messages: Nucleus

89673:DNAJC22
gene id: 89673:DNAJC22
uniprot id: A0A7E6D6R8
uniprot id: A0A7E6D7H3
names: Function
names: Subcellular Location Annotation
messages: May function as a co-chaperone.
messages: Membrane

89673:TBX18
gene id: 89673:TBX18
uniprot id: A0A6J2LHK1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

89673:DACT1
gene id: 89673:DACT1
uniprot id: A0A6J2L740
uniprot id: A0A6J2LCE3
names: Similarity
messages: Belongs to the dapper family.

89673:LOC114503647
gene id: 89673:LOC114503647
uniprot id: A0A6J2MFP4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:NUBP1
gene id: 89673:NUBP1
uniprot id: A0A6J2LXS8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.
messages: Cell projection
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication.
messages: Cytoplasm
messages: Heterotetramer of 2 NUBP1 and 2 NUBP2 chains. Interacts with KIFC1.

89673:MED27
gene id: 89673:MED27
uniprot id: A0A6J2M2G3
uniprot id: A0A7E6DH16
uniprot id: A0A7E6DH54
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 27 family.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

89673:LOC114501006
gene id: 89673:LOC114501006
uniprot id: A0A6J2M5I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114492077
gene id: 89673:LOC114492077
uniprot id: A0A7E6CVC1
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

89673:ATP2A3
gene id: 89673:ATP2A3
uniprot id: A0A7E6EC12
uniprot id: A0A7E6EDL6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

89673:EIF3I
gene id: 89673:EIF3I
uniprot id: A0A6J2LSD0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm
messages: Phosphorylated by TGF-beta type II receptor.

89673:NIF3L1
gene id: 89673:NIF3L1
uniprot id: A0A6J2LAE8
uniprot id: A0A7E6DIU6
uniprot id: A0A7E6DJ22
uniprot id: A0A7E6DJ33
uniprot id: A0A7E6DJ86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
messages: Cytoplasm
messages: Homodimer. Interacts with COPS2. Interacts with THOC7.
messages: May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation.
messages: Nucleus

89673:NPC2
gene id: 89673:NPC2
uniprot id: A0A6J2L4C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPC2 family.
messages: Secreted

89673:LOC114507905
gene id: 89673:LOC114507905
uniprot id: A0A7E6CH34
names: Subcellular Location Annotation
messages: Mitochondrion

89673:LOC114500304
gene id: 89673:LOC114500304
uniprot id: A0A6J2LYE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114493900
gene id: 89673:LOC114493900
uniprot id: A0A6J2LEE1
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

89673:HEG1
gene id: 89673:HEG1
uniprot id: A0A7E6D4E3
uniprot id: A0A7E6D4H0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:VANGL1
gene id: 89673:VANGL1
uniprot id: A0A6J2KYT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

89673:LOC114491709
gene id: 89673:LOC114491709
uniprot id: A0A6J2L228
uniprot id: A0A6J2L2R6
uniprot id: A0A6J2L6F3
names: Similarity
messages: Belongs to the cyclin family. Cyclin Y subfamily.

89673:NDOR1
gene id: 89673:NDOR1
uniprot id: A0A6J2LIH1
uniprot id: A0A6J2LJV9
uniprot id: A0A7E6DH34
uniprot id: A0A7E6DHG6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Interacts with CIAPIN1; as part of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of CIAPIN1, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. It can also reduce the [2Fe-2S] cluster of CISD1 and activate this protein implicated in Fe/S cluster repair.
messages: perinuclear region

89673:LTC4S
gene id: 89673:LTC4S
uniprot id: A0A6J2N2P0
uniprot id: A0A7E6CSV9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:LOC114500745
gene id: 89673:LOC114500745
uniprot id: A0A6J2LZZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ABRAXAS2
gene id: 89673:ABRAXAS2
uniprot id: A0A6J2LSZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM175 family. Abro1 subfamily.
messages: Nucleus
messages: spindle pole

89673:HDAC9
gene id: 89673:HDAC9
uniprot id: A0A6J2MLY6
uniprot id: A0A6J2MNR7
uniprot id: A0A6J2MNV4
uniprot id: A0A7E6CHT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

89673:COG2
gene id: 89673:COG2
uniprot id: A0A6J2N569
uniprot id: A0A7E6CYC4
names: Similarity
messages: Belongs to the COG2 family.

89673:KIF19
gene id: 89673:KIF19
uniprot id: A0A6J2MEJ1
uniprot id: A0A7E6EEZ2
uniprot id: A0A7E6EF83
uniprot id: A0A7E6EG71
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

89673:CDK15
gene id: 89673:CDK15
uniprot id: A0A6J2LFB8
uniprot id: A0A7E6DIY7
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:STARD13
gene id: 89673:STARD13
uniprot id: A0A6J2MRX8
uniprot id: A0A7E6CJJ3
uniprot id: A0A7E6CJJ6
uniprot id: A0A7E6CJM4
names: Subcellular Location Annotation
messages: Cytoplasm

89673:LOC114490179
gene id: 89673:LOC114490179
uniprot id: A0A6J2KWW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:KCNJ12
gene id: 89673:KCNJ12
uniprot id: A0A6J2NEA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ12 subfamily.
messages: Cell membrane
messages: Membrane

89673:ATP6V1E2
gene id: 89673:ATP6V1E2
uniprot id: A0A6J2M4I1
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

89673:LOC114488196
gene id: 89673:LOC114488196
uniprot id: A0A6J2KSN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKD family.
messages: Cell autonomous antagonist of the canonical Wnt signaling pathway.
messages: Cell membrane
messages: Cytoplasm

89673:LOC114513056
gene id: 89673:LOC114513056
uniprot id: A0A7E6D715
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:MYF6
gene id: 89673:MYF6
uniprot id: A0A6J2NAM6
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114495180
gene id: 89673:LOC114495180
uniprot id: A0A7E6DH86
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

89673:LOC114498889
gene id: 89673:LOC114498889
uniprot id: A0A7E6DXK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:RNF146
gene id: 89673:RNF146
uniprot id: A0A6J2LBF8
names: Domain
names: Function
names: PTM
names: Subcellular Location Annotation
messages: E3 ubiquitin-protein ligase that specifically binds poly-ADP-ribosylated proteins and mediates their ubiquitination and subsequent degradation.
messages: The WWE domain mediates non-covalent poly(ADP-ribose)-binding.
messages: Ubiquitinated; autoubiquitinated.
messages: cytosol

89673:GABRA1
gene id: 89673:GABRA1
uniprot id: A0A7E6CRE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA1 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

89673:NOTUM
gene id: 89673:NOTUM
uniprot id: A0A6J2MA35
names: Similarity
messages: Belongs to the pectinacetylesterase family. Notum subfamily.

89673:KCNA1
gene id: 89673:KCNA1
uniprot id: A0A6J2N640
names: Subcellular Location Annotation
messages: Membrane

89673:TRAF3
gene id: 89673:TRAF3
uniprot id: A0A6J2L639
uniprot id: A0A6J2L8D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

89673:CDSN
gene id: 89673:CDSN
uniprot id: A0A7E6DLD4
names: Function
names: Subcellular Location Annotation
messages: Important for the epidermal barrier integrity.
messages: Secreted

89673:INSM2
gene id: 89673:INSM2
uniprot id: A0A6J2L330
names: Subcellular Location Annotation
messages: Nucleus

89673:MRTO4
gene id: 89673:MRTO4
uniprot id: A0A6J2LQT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the pre-60S ribosomal particle.
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
messages: Cytoplasm
messages: nucleolus

89673:DNASE2
gene id: 89673:DNASE2
uniprot id: A0A6J2MAR0
names: Similarity
messages: Belongs to the DNase II family.

89673:PIF1
gene id: 89673:PIF1
uniprot id: A0A7E6CFT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the helicase family. PIF1 subfamily.
messages: DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA ends. Releases telomerase by unwinding the short telomerase RNA/telomeric DNA hybrid that is the intermediate in the telomerase reaction. Possesses an intrinsic strand annealing activity.
messages: Mitochondrion
messages: Monomer. Interacts with telomerase.
messages: Nucleus

89673:COQ6
gene id: 89673:COQ6
uniprot id: A0A6J2L3D2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiH/COQ6 family.
messages: Cell projection
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ7.
messages: FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
messages: Golgi apparatus
messages: Mitochondrion inner membrane

89673:CDKAL1
gene id: 89673:CDKAL1
uniprot id: A0A6J2LMV7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
messages: Endoplasmic reticulum membrane

89673:SERPINH1
gene id: 89673:SERPINH1
uniprot id: A0A6J2LWN1
names: Function
names: Similarity
messages: Belongs to the serpin family.
messages: Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.

89673:PER2
gene id: 89673:PER2
uniprot id: A0A7E6DHR8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

89673:RUNDC3B
gene id: 89673:RUNDC3B
uniprot id: A0A6J2MMQ6
uniprot id: A0A6J2MPM2
uniprot id: A0A6J2MU83
uniprot id: A0A7E6CHV7
uniprot id: A0A7E6CI54
uniprot id: A0A7E6CI99
names: Similarity
names: Subunit
messages: Belongs to the RUNDC3 family.
messages: Interacts with RAP2A.

89673:ATP1A1
gene id: 89673:ATP1A1
uniprot id: A0A6J2KUY7
uniprot id: A0A6J2KY86
uniprot id: A0A7E6CWQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Membrane

89673:FGF6
gene id: 89673:FGF6
uniprot id: A0A6J2N660
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

89673:FABP5
gene id: 89673:FABP5
uniprot id: A0A6J2M3L4
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

89673:CLCF1
gene id: 89673:CLCF1
uniprot id: A0A6J2M5B4
uniprot id: A0A7E6E3P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

89673:CACNB3
gene id: 89673:CACNB3
uniprot id: A0A6J2N5Q5
uniprot id: A0A6J2N7H5
uniprot id: A0A7E6D6W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: Cytoplasm

89673:ARL5C
gene id: 89673:ARL5C
uniprot id: A0A6J2MEA4
uniprot id: A0A7E6EEE8
uniprot id: A0A7E6EFK5
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

89673:LOC114496528
gene id: 89673:LOC114496528
uniprot id: A0A6J2LPY2
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

89673:MAP4K1
gene id: 89673:MAP4K1
uniprot id: A0A6J2N2Y5
uniprot id: A0A7E6CPV5
uniprot id: A0A7E6CSC8
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

89673:LOC114498907
gene id: 89673:LOC114498907
uniprot id: A0A7E6E1A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:EIF2S2
gene id: 89673:EIF2S2
uniprot id: A0A6J2MHD8
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

89673:DAD1
gene id: 89673:DAD1
uniprot id: A0A6J2L666
uniprot id: A0A7E6E5K5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DAD/OST2 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

89673:TSPAN1
gene id: 89673:TSPAN1
uniprot id: A0A6J2LSB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

89673:MYO1C
gene id: 89673:MYO1C
uniprot id: A0A6J2M4Y8
uniprot id: A0A6J2M724
uniprot id: A0A6J2MAJ0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

89673:DNAAF2
gene id: 89673:DNAAF2
uniprot id: A0A7E6DZJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PIH1 family. Kintoun subfamily.
messages: Cytoplasm
messages: Interacts with CFAP300. Interacts with DNAI2 and HSPA1A. Interacts with DYX1C1. Interacts with PIH1D3.
messages: Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment.

89673:LOC114498124
gene id: 89673:LOC114498124
uniprot id: A0A6J2LSN1
uniprot id: A0A7E6DTC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIG1 family.
messages: Membrane

89673:BTG3
gene id: 89673:BTG3
uniprot id: A0A7E6D349
names: Similarity
messages: Belongs to the BTG family.

89673:ITGA9
gene id: 89673:ITGA9
uniprot id: A0A6J2M922
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

89673:MYH7
gene id: 89673:MYH7
uniprot id: A0A6J2L147
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: myofibril

89673:SH2B2
gene id: 89673:SH2B2
uniprot id: A0A6J2LYH8
uniprot id: A0A7E6DBC8
uniprot id: A0A7E6DBI9
names: Similarity
messages: Belongs to the SH2B adapter family.

89673:PAPSS2
gene id: 89673:PAPSS2
uniprot id: A0A7E6DVZ1
names: Similarity
messages: In the C-terminal section; belongs to the sulfate adenylyltransferase family.
messages: In the N-terminal section; belongs to the APS kinase family.

89673:SLC22A3
gene id: 89673:SLC22A3
uniprot id: A0A6J2KWN2
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

89673:TFDP2
gene id: 89673:TFDP2
uniprot id: A0A6J2M3G5
uniprot id: A0A6J2M496
uniprot id: A0A6J2M727
uniprot id: A0A6J2M7N0
uniprot id: A0A6J2M7N6
uniprot id: A0A7E6E5J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

89673:GPD2
gene id: 89673:GPD2
uniprot id: A0A6J2LBK3
names: Function
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta-cell glucose-sensing device.

89673:GDF5
gene id: 89673:GDF5
uniprot id: A0A6J2ML12
names: Similarity
messages: Belongs to the TGF-beta family.

89673:ANKRD13A
gene id: 89673:ANKRD13A
uniprot id: A0A6J2MV60
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

89673:SLCO6A1
gene id: 89673:SLCO6A1
uniprot id: A0A6J2LFN9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:LTA4H
gene id: 89673:LTA4H
uniprot id: A0A6J2N7U7
uniprot id: A0A7E6D7Z2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

89673:LOC114495176
gene id: 89673:LOC114495176
uniprot id: A0A6J2LJA2
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

89673:LOC114495079
gene id: 89673:LOC114495079
uniprot id: A0A6J2LIX5
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

89673:LOC114499157
gene id: 89673:LOC114499157
uniprot id: A0A7E6E3H3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

89673:LOC114500595
gene id: 89673:LOC114500595
uniprot id: A0A6J2M0L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114506519
gene id: 89673:LOC114506519
uniprot id: A0A6J2MQ16
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space
messages: Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

89673:HNRNPDL
gene id: 89673:HNRNPDL
uniprot id: A0A7E6DWQ9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

89673:OPRK1
gene id: 89673:OPRK1
uniprot id: A0A6J2M8X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain. Plays a role in mediating reduced physical activity upon treatment with synthetic opioids. Plays a role in the regulation of salivation in response to synthetic opioids. May play a role in arousal and regulation of autonomic and neuroendocrine functions.
messages: Interacts with NHERF1. Interacts with GABARAPL1.
messages: Membrane

89673:CPB1
gene id: 89673:CPB1
uniprot id: A0A6J2L045
names: Similarity
messages: Belongs to the peptidase M14 family.

89673:GPAT3
gene id: 89673:GPAT3
uniprot id: A0A6J2LCS7
uniprot id: A0A7E6DVQ1
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

89673:LOC114507243
gene id: 89673:LOC114507243
uniprot id: A0A6J2MN47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

89673:SLCO5A1
gene id: 89673:SLCO5A1
uniprot id: A0A6J2NAZ2
uniprot id: A0A7E6E7Q8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:TNFSF4
gene id: 89673:TNFSF4
uniprot id: A0A6J2N9A5
names: Similarity
messages: Belongs to the tumor necrosis factor family.

89673:NDUFB7
gene id: 89673:NDUFB7
uniprot id: A0A6J2MAX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB7 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

89673:LOC118499356
gene id: 89673:LOC118499356
uniprot id: A0A7E6D9E5
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

89673:SLC16A14
gene id: 89673:SLC16A14
uniprot id: A0A6J2LG65
uniprot id: A0A7E6DHU2
names: Subcellular Location Annotation
messages: Membrane

89673:ANP32E
gene id: 89673:ANP32E
uniprot id: A0A6J2KTS8
uniprot id: A0A6J2KVZ6
uniprot id: A0A7E6CWB9
uniprot id: A0A7E6CWP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANP32 family.
messages: Multifunctional protein that is involved in the regulation of many processes.
messages: Nucleus

89673:WNT6
gene id: 89673:WNT6
uniprot id: A0A6J2LGZ6
uniprot id: A0A7E6DIB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

89673:SNTB2
gene id: 89673:SNTB2
uniprot id: A0A6J2KR17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

89673:KLHL21
gene id: 89673:KLHL21
uniprot id: A0A6J2LMR4
names: Subcellular Location Annotation
messages: spindle

89673:MIGA1
gene id: 89673:MIGA1
uniprot id: A0A6J2LP52
uniprot id: A0A7E6DSQ3
uniprot id: A0A7E6DTB7
names: Similarity
messages: Belongs to the mitoguardin family.

89673:PLA2G2A
gene id: 89673:PLA2G2A
uniprot id: A0A6J2LUX7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

89673:LOC114510641
gene id: 89673:LOC114510641
uniprot id: A0A6J2MXT4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.

89673:LOC114489892
gene id: 89673:LOC114489892
uniprot id: A0A6J2KWG1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

89673:LOC114510220
gene id: 89673:LOC114510220
uniprot id: A0A7E6CVB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114502930
gene id: 89673:LOC114502930
uniprot id: A0A6J2MCY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYBC1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:HOXB7
gene id: 89673:HOXB7
uniprot id: A0A6J2MI18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

89673:NTHL1
gene id: 89673:NTHL1
uniprot id: A0A6J2LW92
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nth/MutY family.
messages: Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.
messages: Binds 1 [4Fe-4S] cluster. The cluster does not appear to play a role in catalysis, but is probably involved in the proper positioning of the enzyme along the DNA strand.
messages: Interacts with YBX1.
messages: Mitochondrion
messages: Nucleus

89673:CPLANE2
gene id: 89673:CPLANE2
uniprot id: A0A6J2LPB3
uniprot id: A0A7E6DPZ2
uniprot id: A0A7E6DQ14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Potential effector of the planar cell polarity signaling pathway. Plays a role in targeted membrane trafficking most probably at the level of vesicle fusion with membranes. Involved in cilium biogenesis by regulating the transport of cargo proteins to the basal body and to the apical tips of cilia. More generally involved in exocytosis in secretory cells.
messages: cilium basal body

89673:LOC114511166
gene id: 89673:LOC114511166
uniprot id: A0A6J2N6S8
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

89673:LOC114488869
gene id: 89673:LOC114488869
uniprot id: A0A6J2KZ01
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:TRPC3
gene id: 89673:TRPC3
uniprot id: A0A6J2M9W9
uniprot id: A0A6J2MCZ8
uniprot id: A0A7E6E7W1
names: Subcellular Location Annotation
messages: Membrane

89673:TNPO2
gene id: 89673:TNPO2
uniprot id: A0A6J2MFS8
names: Subcellular Location Annotation
messages: Cytoplasm

89673:GJA4
gene id: 89673:GJA4
uniprot id: A0A6J2LQ99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

89673:NR4A2
gene id: 89673:NR4A2
uniprot id: A0A6J2LCE5
uniprot id: A0A7E6DJU6
uniprot id: A0A7E6DK42
uniprot id: A0A7E6DKA0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family.
messages: Cytoplasm
messages: Interacts with SFPQ, NCOR2, SIN3A and HADC1. The interaction with NCOR2 increases in the absence of PITX3. Interacts with PER2.
messages: Nucleus

89673:GPR68
gene id: 89673:GPR68
uniprot id: A0A7E6CQ76
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:FNTB
gene id: 89673:FNTB
uniprot id: A0A6J2L189
uniprot id: A0A7E6CIW8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.
messages: Heterodimer of FNTA and FNTB.

89673:CACNA1B
gene id: 89673:CACNA1B
uniprot id: A0A6J2LDZ6
uniprot id: A0A7E6DH55
uniprot id: A0A7E6DH60
uniprot id: A0A7E6DH67
uniprot id: A0A7E6DHB0
uniprot id: A0A7E6DHC0
uniprot id: A0A7E6DHD5
uniprot id: A0A7E6DHE1
uniprot id: A0A7E6DHE3
uniprot id: A0A7E6DHE7
uniprot id: A0A7E6DHE9
uniprot id: A0A7E6DHF4
uniprot id: A0A7E6DHI0
uniprot id: A0A7E6DHI6
uniprot id: A0A7E6DHJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This alpha-1B subunit gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated' (HVA) group. They are involved in pain signaling. Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons.

89673:LOC114500674
gene id: 89673:LOC114500674
uniprot id: A0A6J2LZQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ZYG11B
gene id: 89673:ZYG11B
uniprot id: A0A6J2LQD3
uniprot id: A0A7E6DT57
names: Similarity
messages: Belongs to the zyg-11 family.

89673:CNIH2
gene id: 89673:CNIH2
uniprot id: A0A6J2LXR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

89673:COPS4
gene id: 89673:COPS4
uniprot id: A0A6J2L3U1
uniprot id: A0A7E6DWG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN4 family.
messages: Nucleus
messages: Vesicle
messages: synaptic vesicle

89673:ETHE1
gene id: 89673:ETHE1
uniprot id: A0A6J2N0J8
uniprot id: A0A7E6CPX8
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

89673:LOC114509173
gene id: 89673:LOC114509173
uniprot id: A0A6J2MU99
uniprot id: A0A7E6CV03
uniprot id: A0A7E6CVA1
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

89673:ANKRD34A
gene id: 89673:ANKRD34A
uniprot id: A0A6J2L0C6
uniprot id: A0A7E6CW14
names: Similarity
messages: Belongs to the ANKRD34 family.

89673:TELO2
gene id: 89673:TELO2
uniprot id: A0A6J2N5K6
names: Similarity
messages: Belongs to the TEL2 family.

89673:MGAT5B
gene id: 89673:MGAT5B
uniprot id: A0A6J2MDJ1
uniprot id: A0A6J2ME41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 18 family.
messages: Golgi apparatus membrane
messages: Membrane

89673:PTPRJ
gene id: 89673:PTPRJ
uniprot id: A0A6J2LXK5
uniprot id: A0A7E6E1R1
uniprot id: A0A7E6E1X8
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily.

89673:GJA5
gene id: 89673:GJA5
uniprot id: A0A6J2KZV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

89673:IL36B
gene id: 89673:IL36B
uniprot id: A0A6J2LSA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens.
messages: Belongs to the IL-1 family.
messages: Secreted

89673:DRD3
gene id: 89673:DRD3
uniprot id: A0A6J2L027
uniprot id: A0A6J2L550
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation.
messages: Membrane

89673:GPR101
gene id: 89673:GPR101
uniprot id: A0A6J2MIG5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:LOC114503924
gene id: 89673:LOC114503924
uniprot id: A0A6J2MG95
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114508079
gene id: 89673:LOC114508079
uniprot id: A0A6J2MVJ9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

89673:AMPD1
gene id: 89673:AMPD1
uniprot id: A0A6J2KU16
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

89673:SF3A3
gene id: 89673:SF3A3
uniprot id: A0A6J2LR82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3A3 family.
messages: Nucleus

89673:LOC114512052
gene id: 89673:LOC114512052
uniprot id: A0A6J2N4H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:FDXR
gene id: 89673:FDXR
uniprot id: A0A6J2MDG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferredoxin--NADP reductase type 1 family.
messages: Mitochondrion
messages: Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver.

89673:MTMR3
gene id: 89673:MTMR3
uniprot id: A0A6J2MT19
uniprot id: A0A6J2MUM9
uniprot id: A0A6J2MUP4
uniprot id: A0A7E6CSP5
uniprot id: A0A7E6CSP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm
messages: Membrane

89673:VARS2
gene id: 89673:VARS2
uniprot id: A0A6J2LCR5
uniprot id: A0A7E6DKN7
uniprot id: A0A7E6DLC3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

89673:LOC114492373
gene id: 89673:LOC114492373
uniprot id: A0A7E6D9X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

89673:PSMB2
gene id: 89673:PSMB2
uniprot id: A0A6J2LQJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

89673:CARMIL3
gene id: 89673:CARMIL3
uniprot id: A0A6J2L7M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CARMIL family.
messages: Cytoplasm

89673:OVCH1
gene id: 89673:OVCH1
uniprot id: A0A7E6D065
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:CDH15
gene id: 89673:CDH15
uniprot id: A0A6J2KSR4
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

89673:MMP2
gene id: 89673:MMP2
uniprot id: A0A6J2KRE3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.
messages: extracellular matrix

89673:LOC114490008
gene id: 89673:LOC114490008
uniprot id: A0A6J2KWV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

89673:LOC114510890
gene id: 89673:LOC114510890
uniprot id: A0A7E6CQW0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL27 family.

89673:CXXC1
gene id: 89673:CXXC1
uniprot id: A0A6J2MPG0
uniprot id: A0A7E6CGQ1
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114498416
gene id: 89673:LOC114498416
uniprot id: A0A6J2LQS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:C2
gene id: 89673:C2
uniprot id: A0A6J2LGR3
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:SLC41A1
gene id: 89673:SLC41A1
uniprot id: A0A6J2N859
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

89673:PARK7
gene id: 89673:PARK7
uniprot id: A0A6J2LT54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C56 family.
messages: Membrane raft

89673:SH3GL1
gene id: 89673:SH3GL1
uniprot id: A0A6J2M9R4
uniprot id: A0A7E6E8Y2
uniprot id: A0A7E6E9Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Membrane

89673:ECI1
gene id: 89673:ECI1
uniprot id: A0A6J2LRP1
uniprot id: A0A7E6DC78
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

89673:SFTPD
gene id: 89673:SFTPD
uniprot id: A0A7E6DTU8
uniprot id: A0A7E6DU02
uniprot id: A0A7E6DUG7
uniprot id: A0A7E6DUT4
uniprot id: A0A7E6DV49
names: Similarity
names: Subunit
messages: Belongs to the SFTPD family.
messages: Oligomeric complex of 4 set of homotrimers.

89673:SMO
gene id: 89673:SMO
uniprot id: A0A6J2MTP7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: cilium

89673:RAN
gene id: 89673:RAN
uniprot id: A0A6J2L1D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ran family.
messages: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.
messages: Nucleus

89673:HAGH
gene id: 89673:HAGH
uniprot id: A0A6J2MZS4
uniprot id: A0A7E6DD57
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

89673:IL33
gene id: 89673:IL33
uniprot id: A0A7E6DAM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family. Highly divergent.
messages: Chromosome
messages: Nucleus
messages: Secreted
messages: Vesicle
messages: secretory vesicle

89673:YIPF7
gene id: 89673:YIPF7
uniprot id: A0A7E6DCL4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:SUOX
gene id: 89673:SUOX
uniprot id: A0A6J2NEP7
uniprot id: A0A7E6D8Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome b5 family.
messages: Catalyzes the oxidation of sulfite to sulfate, the terminal reaction in the oxidative degradation of sulfur-containing amino acids.
messages: Mitochondrion intermembrane space

89673:ADCK1
gene id: 89673:ADCK1
uniprot id: A0A6J2L6T1
uniprot id: A0A7E6CRC3
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

89673:ATP5F1A
gene id: 89673:ATP5F1A
uniprot id: A0A6J2MNW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

89673:POPDC3
gene id: 89673:POPDC3
uniprot id: A0A6J2LHD4
names: Similarity
messages: Belongs to the popeye family.

89673:TNFRSF4
gene id: 89673:TNFRSF4
uniprot id: A0A6J2LPD9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114503176
gene id: 89673:LOC114503176
uniprot id: A0A6J2M8V2
names: Function
names: Subcellular Location Annotation
messages: Promotes integrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells.
messages: extracellular matrix

89673:RAB3A
gene id: 89673:RAB3A
uniprot id: A0A6J2M7C0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

89673:LOC114510247
gene id: 89673:LOC114510247
uniprot id: A0A7E6CRC0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CXXC4
gene id: 89673:CXXC4
uniprot id: A0A6J2LD97
uniprot id: A0A7E6DSC2
names: Subcellular Location Annotation
messages: Cytoplasm

89673:ELMO1
gene id: 89673:ELMO1
uniprot id: A0A6J2MNP6
uniprot id: A0A6J2MQP5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

89673:LOC114492627
gene id: 89673:LOC114492627
uniprot id: A0A6J2L7F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DUOXA family.
messages: Membrane

89673:AKIRIN1
gene id: 89673:AKIRIN1
uniprot id: A0A6J2LNG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

89673:GFRAL
gene id: 89673:GFRAL
uniprot id: A0A6J2LGB9
names: Similarity
messages: Belongs to the GDNFR family.

89673:USO1
gene id: 89673:USO1
uniprot id: A0A6J2L8R2
uniprot id: A0A6J2LAG2
uniprot id: A0A6J2LDA3
uniprot id: A0A7E6DGD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VDP/USO1/EDE1 family.
messages: Membrane

89673:SLC23A2
gene id: 89673:SLC23A2
uniprot id: A0A6J2MHL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

89673:DVL2
gene id: 89673:DVL2
uniprot id: A0A6J2NDG9
uniprot id: A0A6J2NJ53
uniprot id: A0A7E6ECD5
names: Similarity
messages: Belongs to the DSH family.

89673:IGFBP6
gene id: 89673:IGFBP6
uniprot id: A0A6J2NDQ3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:MB21D2
gene id: 89673:MB21D2
uniprot id: A0A6J2L1B0
uniprot id: A0A6J2L346
names: Similarity
messages: Belongs to the mab-21 family.

89673:LOC114514573
gene id: 89673:LOC114514573
uniprot id: A0A6J2NCP4
uniprot id: A0A7E6E8C3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme c group covalently per subunit.
messages: Membrane
messages: Mitochondrion inner membrane

89673:GLO1
gene id: 89673:GLO1
uniprot id: A0A6J2LF90
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

89673:LOC114500592
gene id: 89673:LOC114500592
uniprot id: A0A6J2M1H7
names: Similarity
messages: Belongs to the histone H3 family.

89673:DPY19L1
gene id: 89673:DPY19L1
uniprot id: A0A6J2MUC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

89673:TIGD2
gene id: 89673:TIGD2
uniprot id: A0A6J2L852
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114512477
gene id: 89673:LOC114512477
uniprot id: A0A6J2N416
uniprot id: A0A7E6D163
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114499865
gene id: 89673:LOC114499865
uniprot id: A0A6J2LYT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114499172
gene id: 89673:LOC114499172
uniprot id: A0A6J2LYL0
names: Similarity
messages: Belongs to the CD225/Dispanin family.

89673:ARCN1
gene id: 89673:ARCN1
uniprot id: A0A6J2LU92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

89673:PRKCZ
gene id: 89673:PRKCZ
uniprot id: A0A6J2LL80
uniprot id: A0A7E6DPH5
uniprot id: A0A7E6DPI7
uniprot id: A0A7E6DQ21
uniprot id: A0A7E6DQK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

89673:SOHLH1
gene id: 89673:SOHLH1
uniprot id: A0A7E6DAP2
names: Subcellular Location Annotation
messages: Nucleus

89673:DHRS7B
gene id: 89673:DHRS7B
uniprot id: A0A7E6EG70
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

89673:LOC114500905
gene id: 89673:LOC114500905
uniprot id: A0A7E6DZ88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mago nashi family.
messages: Nucleus

89673:PTS
gene id: 89673:PTS
uniprot id: A0A6J2M4Q3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the PTPS family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin.

89673:B3GNT4
gene id: 89673:B3GNT4
uniprot id: A0A6J2MWB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

89673:CLDN34
gene id: 89673:CLDN34
uniprot id: A0A6J2L1M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

89673:LOC114512472
gene id: 89673:LOC114512472
uniprot id: A0A6J2N3P8
uniprot id: A0A6J2N5V4
uniprot id: A0A7E6CYI3
uniprot id: A0A7E6CYM9
uniprot id: A0A7E6CYN3
uniprot id: A0A7E6CYZ1
uniprot id: A0A7E6CYZ6
uniprot id: A0A7E6CZG7
uniprot id: A0A7E6CZH2
uniprot id: A0A7E6D153
uniprot id: A0A7E6D158
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:GPBP1L1
gene id: 89673:GPBP1L1
uniprot id: A0A6J2LQK4
uniprot id: A0A7E6DRT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vasculin family.
messages: Nucleus

89673:TMEM18
gene id: 89673:TMEM18
uniprot id: A0A6J2M436
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM18 family.
messages: Membrane
messages: Nucleus membrane

89673:CSRNP3
gene id: 89673:CSRNP3
uniprot id: A0A7E6DJL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

89673:LOC118502201
gene id: 89673:LOC118502201
uniprot id: A0A7E6EDE7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

89673:LOC114492296
gene id: 89673:LOC114492296
uniprot id: A0A6J2L4A2
uniprot id: A0A7E6DE26
uniprot id: A0A7E6DE42
uniprot id: A0A7E6DE43
uniprot id: A0A7E6DE68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

89673:KPNA6
gene id: 89673:KPNA6
uniprot id: A0A6J2LMK8
names: Function
names: Similarity
messages: Belongs to the importin alpha family.
messages: Functions in nuclear protein import.

89673:LOC114502887
gene id: 89673:LOC114502887
uniprot id: A0A6J2MCT6
names: Similarity
messages: Belongs to the intermediate filament family.

89673:CFAP206
gene id: 89673:CFAP206
uniprot id: A0A6J2LEA2
uniprot id: A0A7E6DN07
uniprot id: A0A7E6DNA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP206 family.
messages: cilium axoneme

89673:KRT19
gene id: 89673:KRT19
uniprot id: A0A6J2MHD5
names: Similarity
messages: Belongs to the intermediate filament family.

89673:LOC114511479
gene id: 89673:LOC114511479
uniprot id: A0A6J2N7Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 11 family.
messages: Golgi stack membrane
messages: Membrane

89673:ITPK1
gene id: 89673:ITPK1
uniprot id: A0A6J2L626
uniprot id: A0A7E6CQP0
uniprot id: A0A7E6CR64
names: Similarity
messages: Belongs to the ITPK1 family.

89673:LOC118498388
gene id: 89673:LOC118498388
uniprot id: A0A7E6CYZ3
names: Similarity
messages: Belongs to the PICALM/SNAP91 family.

89673:LOC114491906
gene id: 89673:LOC114491906
uniprot id: A0A6J2L8U6
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

89673:SAP130
gene id: 89673:SAP130
uniprot id: A0A6J2L9Q2
uniprot id: A0A6J2LA96
uniprot id: A0A6J2LAA2
uniprot id: A0A6J2LBI8
uniprot id: A0A6J2LBJ4
uniprot id: A0A6J2LE94
uniprot id: A0A6J2LE99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAP130 family.
messages: Nucleus

89673:LOC114510842
gene id: 89673:LOC114510842
uniprot id: A0A6J2N4H4
names: Similarity
messages: Belongs to the MHC class I family.

89673:EPHA2
gene id: 89673:EPHA2
uniprot id: A0A6J2LLG1
uniprot id: A0A7E6DQ03
names: Subcellular Location Annotation
messages: Membrane

89673:STAB2
gene id: 89673:STAB2
uniprot id: A0A7E6D8Q4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:SNX6
gene id: 89673:SNX6
uniprot id: A0A6J2L4K6
uniprot id: A0A6J2L9Z1
names: Function
names: Similarity
messages: Belongs to the sorting nexin family.
messages: Involved in several stages of intracellular trafficking.

89673:TTC19
gene id: 89673:TTC19
uniprot id: A0A6J2NDK6
uniprot id: A0A7E6EB08
uniprot id: A0A7E6ECK8
uniprot id: A0A7E6ECX6
names: Similarity
messages: Belongs to the TTC19 family.

89673:RNF13
gene id: 89673:RNF13
uniprot id: A0A6J2KXV5
names: Subcellular Location Annotation
messages: Membrane

89673:KRT35
gene id: 89673:KRT35
uniprot id: A0A6J2M8Z7
names: Similarity
messages: Belongs to the intermediate filament family.

89673:HSPA4L
gene id: 89673:HSPA4L
uniprot id: A0A6J2M6P6
names: Similarity
messages: Belongs to the heat shock protein 70 family.

89673:MTRF1L
gene id: 89673:MTRF1L
uniprot id: A0A6J2LF44
uniprot id: A0A7E6DNS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

89673:TPD52
gene id: 89673:TPD52
uniprot id: A0A6J2M1H3
uniprot id: A0A6J2M3R8
uniprot id: A0A6J2M746
uniprot id: A0A7E6E5R9
uniprot id: A0A7E6E5S4
uniprot id: A0A7E6E6C2
uniprot id: A0A7E6E6C5
uniprot id: A0A7E6E6C9
uniprot id: A0A7E6E6L3
uniprot id: A0A7E6E6L9
uniprot id: A0A7E6E6M3
uniprot id: A0A7E6E7A4
uniprot id: A0A7E6E7B0
uniprot id: A0A7E6E7B6
uniprot id: A0A7E6E7G3
uniprot id: A0A7E6E7G8
names: Similarity
messages: Belongs to the TPD52 family.

89673:LOC114498900
gene id: 89673:LOC114498900
uniprot id: A0A6J2LUL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:THOC7
gene id: 89673:THOC7
uniprot id: A0A6J2M8G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC7 family.
messages: Nucleus
messages: Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.

89673:TES
gene id: 89673:TES
uniprot id: A0A6J2MPY8
uniprot id: A0A7E6CIN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prickle / espinas / testin family.
messages: Cytoplasm
messages: Interacts via LIM domain 1 with ZYX. Interacts (via LIM domain 3) with ENAH and VASP. Interacts with ALKBH4, talin, actin, alpha-actinin, GRIP1 and PXN (By similarity). Interacts (via LIM domain 2) with ACTL7A (via N-terminus). Heterodimer with ACTL7A; the heterodimer interacts with ENAH to form a heterotrimer.
messages: Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor.
messages: focal adhesion

89673:LOC114500307
gene id: 89673:LOC114500307
uniprot id: A0A6J2M0H2
uniprot id: A0A7E6E1N9
uniprot id: A0A7E6E1P4
uniprot id: A0A7E6E276
uniprot id: A0A7E6E280
uniprot id: A0A7E6E2D3
uniprot id: A0A7E6E2D8
uniprot id: A0A7E6E324
uniprot id: A0A7E6E331
uniprot id: A0A7E6E343
uniprot id: A0A7E6E347
names: Subcellular Location Annotation
messages: Secreted

89673:MTF2
gene id: 89673:MTF2
uniprot id: A0A6J2LLN7
uniprot id: A0A7E6DT04
uniprot id: A0A7E6DTL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus

89673:HNRNPR
gene id: 89673:HNRNPR
uniprot id: A0A6J2LTB9
uniprot id: A0A6J2LTG4
uniprot id: A0A7E6DQC7
uniprot id: A0A7E6DR27
names: Subcellular Location Annotation
messages: Cytoplasm

89673:LOC114507486
gene id: 89673:LOC114507486
uniprot id: A0A6J2MNM2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:SLC25A28
gene id: 89673:SLC25A28
uniprot id: A0A6J2LM95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

89673:MARCHF9
gene id: 89673:MARCHF9
uniprot id: A0A6J2NFA3
names: Subcellular Location Annotation
messages: Membrane

89673:PLIN1
gene id: 89673:PLIN1
uniprot id: A0A6J2KXW7
names: Similarity
messages: Belongs to the perilipin family.

89673:LOC114499178
gene id: 89673:LOC114499178
uniprot id: A0A6J2LY55
names: Similarity
messages: Belongs to the CD225/Dispanin family.

89673:CARNMT1
gene id: 89673:CARNMT1
uniprot id: A0A6J2MEA7
uniprot id: A0A7E6DF58
names: Similarity
messages: Belongs to the carnosine N-methyltransferase family.

89673:LOC114499022
gene id: 89673:LOC114499022
uniprot id: A0A6J2LUS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CCND2
gene id: 89673:CCND2
uniprot id: A0A6J2NH39
names: Similarity
messages: Belongs to the cyclin family.

89673:LTBR
gene id: 89673:LTBR
uniprot id: A0A6J2N5B7
uniprot id: A0A6J2NBW7
uniprot id: A0A7E6D1Y5
uniprot id: A0A7E6D2N8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:FNIP2
gene id: 89673:FNIP2
uniprot id: A0A6J2M504
uniprot id: A0A6J2M728
uniprot id: A0A6J2MA05
uniprot id: A0A6J2MAJ9
uniprot id: A0A7E6E978
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNIP family.
messages: Lysosome membrane
messages: Membrane

89673:KRR1
gene id: 89673:KRR1
uniprot id: A0A7E6D698
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KRR1 family.
messages: nucleolus

89673:CDC14B
gene id: 89673:CDC14B
uniprot id: A0A6J2N464
uniprot id: A0A6J2NAP6
uniprot id: A0A7E6DEC0
uniprot id: A0A7E6DEC6
uniprot id: A0A7E6DEE8
uniprot id: A0A7E6DEF7
uniprot id: A0A7E6DEF8
uniprot id: A0A7E6DEF9
uniprot id: A0A7E6DEG2
uniprot id: A0A7E6DEG4
uniprot id: A0A7E6DEH1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

89673:LOC114507469
gene id: 89673:LOC114507469
uniprot id: A0A6J2MT07
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

89673:LOC114490160
gene id: 89673:LOC114490160
uniprot id: A0A6J2KXE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SLC5A11
gene id: 89673:SLC5A11
uniprot id: A0A6J2M1W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

89673:SCN10A
gene id: 89673:SCN10A
uniprot id: A0A6J2M3I4
uniprot id: A0A6J2M535
uniprot id: A0A6J2M986
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

89673:MPC2
gene id: 89673:MPC2
uniprot id: A0A6J2N403
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

89673:LOC114500910
gene id: 89673:LOC114500910
uniprot id: A0A6J2M5V4
uniprot id: A0A7E6DC01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM186 family.
messages: Membrane

89673:ABCD3
gene id: 89673:ABCD3
uniprot id: A0A6J2LNL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.
messages: Membrane
messages: Peroxisome membrane

89673:GSK3A
gene id: 89673:GSK3A
uniprot id: A0A6J2N2T3
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

89673:PFAS
gene id: 89673:PFAS
uniprot id: A0A6J2NDK2
names: Similarity
messages: In the N-terminal section; belongs to the FGAMS family.

89673:SEC13
gene id: 89673:SEC13
uniprot id: A0A6J2M5N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Lysosome membrane

89673:LOC114499928
gene id: 89673:LOC114499928
uniprot id: A0A6J2LY39
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

89673:GGA2
gene id: 89673:GGA2
uniprot id: A0A6J2LMK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

89673:LOC114500704
gene id: 89673:LOC114500704
uniprot id: A0A6J2M4V3
uniprot id: A0A7E6E2T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:RRAD
gene id: 89673:RRAD
uniprot id: A0A6J2KUD8
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

89673:SDHD
gene id: 89673:SDHD
uniprot id: A0A6J2LWP1
uniprot id: A0A7E6DZJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CybS family.
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

89673:LOC114502107
gene id: 89673:LOC114502107
uniprot id: A0A7E6E7H0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

89673:LOC114500384
gene id: 89673:LOC114500384
uniprot id: A0A6J2M469
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TFCP2
gene id: 89673:TFCP2
uniprot id: A0A6J2N8W9
uniprot id: A0A7E6D7B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

89673:ATP5PD
gene id: 89673:ATP5PD
uniprot id: A0A6J2M9K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase d subunit family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion inner membrane

89673:SNRPF
gene id: 89673:SNRPF
uniprot id: A0A6J2NDC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

89673:UBE2B
gene id: 89673:UBE2B
uniprot id: A0A6J2MU23
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

89673:LOC114499919
gene id: 89673:LOC114499919
uniprot id: A0A6J2LWZ5
uniprot id: A0A7E6E1T1
names: Function
names: Similarity
messages: Belongs to the SAA family.
messages: Major acute phase reactant. Apolipoprotein of the HDL complex.

89673:LOC114490353
gene id: 89673:LOC114490353
uniprot id: A0A6J2L3B0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:MSX1
gene id: 89673:MSX1
uniprot id: A0A6J2L4T7
names: Subcellular Location Annotation
messages: Nucleus

89673:THPO
gene id: 89673:THPO
uniprot id: A0A6J2L510
uniprot id: A0A7E6D5W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPO/TPO family.
messages: Secreted

89673:CSNK2B
gene id: 89673:CSNK2B
uniprot id: A0A6J2LFB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Participates in Wnt signaling.
messages: Tetramer of two alpha and two beta subunits.

89673:LOC114507437
gene id: 89673:LOC114507437
uniprot id: A0A6J2MSZ7
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

89673:NPNT
gene id: 89673:NPNT
uniprot id: A0A6J2L8N3
uniprot id: A0A6J2L9X3
uniprot id: A0A6J2LDV8
uniprot id: A0A7E6DRK9
names: Caution
names: Similarity
messages: Belongs to the nephronectin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:CDC42SE2
gene id: 89673:CDC42SE2
uniprot id: A0A7E6CUL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Interacts with CDC42 (in GTP-bound form). Interacts weakly with RAC1 and not at all with RHOA.
messages: Membrane
messages: Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages.
messages: cytoskeleton

89673:DIO3
gene id: 89673:DIO3
uniprot id: A0A6J2L5Y3
names: Function
names: Similarity
messages: Belongs to the iodothyronine deiodinase family.
messages: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).

89673:ENGASE
gene id: 89673:ENGASE
uniprot id: A0A6J2MDA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 85 family.
messages: cytosol

89673:PDP2
gene id: 89673:PDP2
uniprot id: A0A7E6CNY3
names: Similarity
messages: Belongs to the PP2C family.

89673:UNG
gene id: 89673:UNG
uniprot id: A0A6J2N175
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
messages: Mitochondrion
messages: Monomer. Interacts with FAM72A.
messages: Nucleus

89673:RPL18A
gene id: 89673:RPL18A
uniprot id: A0A6J2MB00
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL20 family.

89673:GNA11
gene id: 89673:GNA11
uniprot id: A0A6J2M7H2
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

89673:MRPS21
gene id: 89673:MRPS21
uniprot id: A0A6J2KTK3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

89673:XKR7
gene id: 89673:XKR7
uniprot id: A0A6J2MN44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

89673:LOC114511533
gene id: 89673:LOC114511533
uniprot id: A0A7E6CP93
names: Subcellular Location Annotation
messages: Membrane

89673:PPP1R1A
gene id: 89673:PPP1R1A
uniprot id: A0A6J2ND78
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 1 family.

89673:LOC114490029
gene id: 89673:LOC114490029
uniprot id: A0A6J2L087
names: Function
names: Subunit
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

89673:TDRD7
gene id: 89673:TDRD7
uniprot id: A0A6J2N0I0
uniprot id: A0A7E6DFU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TDRD7 family.
messages: Component of specific cytoplasmic RNA granules involved in post-transcriptional regulation of specific genes: probably acts by binding to specific mRNAs and regulating their translation. Required for lens transparency during lens development, by regulating translation of genes such as CRYBB3 and HSPB1 in the developing lens. Also required during spermatogenesis.
messages: Cytoplasm
messages: Found in a mRNP complex, at least composed of TDRD1, TDRD6, TDRD7 and DDX4. Found in a complex containing CABLES1, CDK16 and CDK17. Interacts with CABLES1, CDK17 and PIWIL1.

89673:EDC4
gene id: 89673:EDC4
uniprot id: A0A6J2NJN1
uniprot id: A0A7E6CM28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat EDC4 family.
messages: P-body

89673:RPN1
gene id: 89673:RPN1
uniprot id: A0A6J2MPY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

89673:CTPS2
gene id: 89673:CTPS2
uniprot id: A0A6J2ML98
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

89673:LOC114500292
gene id: 89673:LOC114500292
uniprot id: A0A6J2M3F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CADM3
gene id: 89673:CADM3
uniprot id: A0A6J2N3N0
uniprot id: A0A6J2N926
names: Similarity
messages: Belongs to the nectin family.

89673:LOC114500179
gene id: 89673:LOC114500179
uniprot id: A0A6J2M3F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114500172
gene id: 89673:LOC114500172
uniprot id: A0A6J2M2Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:WASF3
gene id: 89673:WASF3
uniprot id: A0A6J2KZC7
uniprot id: A0A6J2L1K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

89673:STAT4
gene id: 89673:STAT4
uniprot id: A0A6J2LGY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

89673:OVOL3
gene id: 89673:OVOL3
uniprot id: A0A7E6CNW5
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114500353
gene id: 89673:LOC114500353
uniprot id: A0A6J2LZR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SMARCB1
gene id: 89673:SMARCB1
uniprot id: A0A6J2MV01
uniprot id: A0A6J2N032
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNF5 family.
messages: Component of the multiprotein chromatin-remodeling complexes SWI/SNF.
messages: Nucleus

89673:PUS10
gene id: 89673:PUS10
uniprot id: A0A6J2M241
uniprot id: A0A7E6DXJ9
uniprot id: A0A7E6DXZ5
uniprot id: A0A7E6DYU4
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.

89673:LOC114499905
gene id: 89673:LOC114499905
uniprot id: A0A6J2LWW9
names: Similarity
messages: Belongs to the cytochrome P450 family.

89673:PPP1R35
gene id: 89673:PPP1R35
uniprot id: A0A6J2MLU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP1R35 family.
messages: centriole

89673:FEZ1
gene id: 89673:FEZ1
uniprot id: A0A6J2MYZ0
names: Similarity
messages: Belongs to the zygin family.

89673:RNASE10
gene id: 89673:RNASE10
uniprot id: A0A6J2KY33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

89673:BTF3
gene id: 89673:BTF3
uniprot id: A0A6J2M1C2
uniprot id: A0A6J2M3K1
names: Similarity
messages: Belongs to the NAC-beta family.

89673:MRS2
gene id: 89673:MRS2
uniprot id: A0A6J2KYQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mitochondrion inner membrane

89673:TACC3
gene id: 89673:TACC3
uniprot id: A0A6J2KW83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

89673:MPP6
gene id: 89673:MPP6
uniprot id: A0A7E6CHD7
uniprot id: A0A7E6CHU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane

89673:LOC114495561
gene id: 89673:LOC114495561
uniprot id: A0A6J2LIA1
names: Similarity
messages: Belongs to the cytochrome P450 family.

89673:CTSC
gene id: 89673:CTSC
uniprot id: A0A6J2LW46
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C1 family.
messages: Lysosome
messages: Tetramer of heterotrimers consisting of exclusion domain, heavy- and light chains.

89673:ATG4D
gene id: 89673:ATG4D
uniprot id: A0A6J2M5N3
uniprot id: A0A7E6EAA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

89673:ELOVL5
gene id: 89673:ELOVL5
uniprot id: A0A6J2LC29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL5 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: dendrite

89673:SEC16B
gene id: 89673:SEC16B
uniprot id: A0A7E6CXY6
uniprot id: A0A7E6CYS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC16 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.
messages: SEC16A and SEC16B are each present in multiple copies in a heteromeric complex.

89673:EIF3J
gene id: 89673:EIF3J
uniprot id: A0A6J2L571
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit J family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. This subunit binds directly within the mRNA entry channel of the 40S ribosome to the aminoacyl (A) site. It may regulate the interaction between the 43S PIC and mRNA.
messages: Cytoplasm
messages: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.

89673:ALLC
gene id: 89673:ALLC
uniprot id: A0A6J2M610
names: Function
names: Similarity
messages: Belongs to the allantoicase family.
messages: The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals.

89673:ATF7
gene id: 89673:ATF7
uniprot id: A0A6J2N9X1
uniprot id: A0A7E6D977
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

89673:BUD23
gene id: 89673:BUD23
uniprot id: A0A6J2N085
uniprot id: A0A7E6DDH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.
messages: Cytoplasm
messages: Nucleus

89673:LOC114506915
gene id: 89673:LOC114506915
uniprot id: A0A6J2MKJ5
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

89673:SH2D1A
gene id: 89673:SH2D1A
uniprot id: A0A6J2MFA5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2.

89673:LOC114493443
gene id: 89673:LOC114493443
uniprot id: A0A7E6DDU9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

89673:SF3B5
gene id: 89673:SF3B5
uniprot id: A0A6J2LII1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SF3B5 family.
messages: Component of the spliceosome B complex.
messages: Nucleus

89673:RNASEH1
gene id: 89673:RNASEH1
uniprot id: A0A6J2M3E5
names: Function
names: Similarity
messages: Belongs to the RNase H family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

89673:LOC114499220
gene id: 89673:LOC114499220
uniprot id: A0A6J2LVF9
names: Similarity
messages: Belongs to the PRORSD1 family.

89673:SYNPR
gene id: 89673:SYNPR
uniprot id: A0A6J2M5D9
uniprot id: A0A6J2M8W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

89673:IVD
gene id: 89673:IVD
uniprot id: A0A6J2L850
uniprot id: A0A7E6E9G6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

89673:LOC114497501
gene id: 89673:LOC114497501
uniprot id: A0A6J2LMS7
names: Similarity
messages: Belongs to the serpin family.

89673:HOXA10
gene id: 89673:HOXA10
uniprot id: A0A6J2MTS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

89673:LOC114499664
gene id: 89673:LOC114499664
uniprot id: A0A6J2LVS9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space
messages: Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

89673:DLK1
gene id: 89673:DLK1
uniprot id: A0A6J2L5K4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:DHX8
gene id: 89673:DHX8
uniprot id: A0A6J2M9K4
uniprot id: A0A7E6EE38
names: Subcellular Location Annotation
messages: Nucleus

89673:SAMM50
gene id: 89673:SAMM50
uniprot id: A0A6J2N915
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAM50/omp85 family.
messages: Mitochondrion outer membrane

89673:JMY
gene id: 89673:JMY
uniprot id: A0A6J2LCK6
names: Subcellular Location Annotation
messages: Membrane

89673:POLR2A
gene id: 89673:POLR2A
uniprot id: A0A6J2NJJ4
uniprot id: A0A7E6ECC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

89673:LDLRAD3
gene id: 89673:LDLRAD3
uniprot id: A0A6J2M0L5
uniprot id: A0A7E6E1A2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:FES
gene id: 89673:FES
uniprot id: A0A6J2KRE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.
messages: Cell membrane
messages: Membrane
messages: cytoskeleton

89673:LOC114494366
gene id: 89673:LOC114494366
uniprot id: A0A7E6DJV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

89673:PIGO
gene id: 89673:PIGO
uniprot id: A0A6J2NE82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:UBAC2
gene id: 89673:UBAC2
uniprot id: A0A6J2MRP5
uniprot id: A0A6J2MW32
names: Subcellular Location Annotation
messages: Membrane

89673:TMEM11
gene id: 89673:TMEM11
uniprot id: A0A6J2NJD2
uniprot id: A0A7E6EBJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM11 family.
messages: Membrane
messages: Plays a role in mitochondrial morphogenesis.

89673:NUP88
gene id: 89673:NUP88
uniprot id: A0A6J2NJI7
uniprot id: A0A7E6ECI6
names: Subcellular Location Annotation
messages: nuclear pore complex

89673:SLC5A1
gene id: 89673:SLC5A1
uniprot id: A0A6J2MW27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

89673:HKDC1
gene id: 89673:HKDC1
uniprot id: A0A6J2LQW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hexokinase family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: cytosol

89673:KCNAB2
gene id: 89673:KCNAB2
uniprot id: A0A6J2LHU6
uniprot id: A0A6J2LK75
uniprot id: A0A6J2LMR9
uniprot id: A0A7E6DPN7
uniprot id: A0A7E6DPP4
uniprot id: A0A7E6DQS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: axon
messages: cytoskeleton
messages: synaptosome

89673:LOC114498954
gene id: 89673:LOC114498954
uniprot id: A0A7E6E067
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:GANAB
gene id: 89673:GANAB
uniprot id: A0A6J2LTY5
uniprot id: A0A6J2LXB8
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

89673:GPR55
gene id: 89673:GPR55
uniprot id: A0A6J2LAU4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:LOC114512022
gene id: 89673:LOC114512022
uniprot id: A0A6J2N4C6
uniprot id: A0A7E6CY21
uniprot id: A0A7E6CYF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:SLC17A8
gene id: 89673:SLC17A8
uniprot id: A0A6J2N7S9
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114513234
gene id: 89673:LOC114513234
uniprot id: A0A6J2N6U0
names: Similarity
messages: Belongs to the intermediate filament family.

89673:LOC114503164
gene id: 89673:LOC114503164
uniprot id: A0A6J2MAH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SEMA7A
gene id: 89673:SEMA7A
uniprot id: A0A6J2L901
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:GFUS
gene id: 89673:GFUS
uniprot id: A0A6J2NI69
uniprot id: A0A7E6E7X4
uniprot id: A0A7E6E8H7
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

89673:RER1
gene id: 89673:RER1
uniprot id: A0A6J2LP13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RER1 family.
messages: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
messages: Membrane

89673:PRDM16
gene id: 89673:PRDM16
uniprot id: A0A6J2LKQ4
uniprot id: A0A7E6DPL0
uniprot id: A0A7E6DQA3
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114492388
gene id: 89673:LOC114492388
uniprot id: A0A6J2L423
uniprot id: A0A6J2L4P9
uniprot id: A0A6J2L8N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX16 family.
messages: Membrane
messages: Mitochondrion inner membrane

89673:ABCA4
gene id: 89673:ABCA4
uniprot id: A0A6J2LK23
uniprot id: A0A7E6DT18
uniprot id: A0A7E6DT54
uniprot id: A0A7E6DTT8
uniprot id: A0A7E6DU79
names: Subcellular Location Annotation
messages: Membrane

89673:STX19
gene id: 89673:STX19
uniprot id: A0A6J2KYX4
names: Similarity
messages: Belongs to the syntaxin family.

89673:MUC2
gene id: 89673:MUC2
uniprot id: A0A6J2LYN6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114490340
gene id: 89673:LOC114490340
uniprot id: A0A7E6E6C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CDK11A
gene id: 89673:CDK11A
uniprot id: A0A6J2LPK4
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

89673:PSMG1
gene id: 89673:PSMG1
uniprot id: A0A6J2L396
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PSMG1 family.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with psmg2.
messages: Cytoplasm
messages: Forms a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer interacts directly with the PSMA5 and PSMA7 proteasome alpha subunits.
messages: Forms a heterodimer with psmg2.

89673:LOC114503922
gene id: 89673:LOC114503922
uniprot id: A0A6J2MH15
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114508381
gene id: 89673:LOC114508381
uniprot id: A0A6J2MVV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

89673:KMO
gene id: 89673:KMO
uniprot id: A0A6J2N3Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.
messages: Mitochondrion outer membrane

89673:TP53BP2
gene id: 89673:TP53BP2
uniprot id: A0A6J2N5L9
names: Subcellular Location Annotation
messages: Nucleus

89673:HNRNPH2
gene id: 89673:HNRNPH2
uniprot id: A0A6J2MDR8
names: Subcellular Location Annotation
messages: nucleoplasm

89673:ATG9B
gene id: 89673:ATG9B
uniprot id: A0A6J2MNJ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

89673:CXCL6
gene id: 89673:CXCL6
uniprot id: A0A6J2L3F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

89673:LOC118500232
gene id: 89673:LOC118500232
uniprot id: A0A7E6DM52
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:GAREM1
gene id: 89673:GAREM1
uniprot id: A0A6J2MP76
names: Similarity
messages: Belongs to the GAREM family.

89673:JPT2
gene id: 89673:JPT2
uniprot id: A0A6J2LTE7
uniprot id: A0A6J2LYX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

89673:USP15
gene id: 89673:USP15
uniprot id: A0A6J2NAT2
uniprot id: A0A6J2NFL3
uniprot id: A0A7E6D5S6
uniprot id: A0A7E6D5V4
uniprot id: A0A7E6D6G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: Nucleus

89673:PHKG2
gene id: 89673:PHKG2
uniprot id: A0A6J2L9K4
uniprot id: A0A7E6DDW8
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily.
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.

89673:LOC114507399
gene id: 89673:LOC114507399
uniprot id: A0A7E6CH94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ZIM2
gene id: 89673:ZIM2
uniprot id: A0A7E6CRD3
names: Subcellular Location Annotation
messages: Nucleus

89673:POT1
gene id: 89673:POT1
uniprot id: A0A6J2MR18
uniprot id: A0A7E6CKP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the telombin family.
messages: Nucleus
messages: telomere

89673:NHS
gene id: 89673:NHS
uniprot id: A0A6J2MD73
uniprot id: A0A6J2MFB8
uniprot id: A0A6J2MJ79
uniprot id: A0A7E6D115
names: Similarity
messages: Belongs to the NHS family.

89673:PIK3C2B
gene id: 89673:PIK3C2B
uniprot id: A0A6J2N1R1
uniprot id: A0A7E6CWS0
uniprot id: A0A7E6CXH9
uniprot id: A0A7E6CZB2
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

89673:LOC114500156
gene id: 89673:LOC114500156
uniprot id: A0A6J2LYZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SF1
gene id: 89673:SF1
uniprot id: A0A6J2LW63
uniprot id: A0A6J2LW68
uniprot id: A0A6J2LXB1
uniprot id: A0A6J2LY96
uniprot id: A0A6J2M180
uniprot id: A0A6J2M187
uniprot id: A0A6J2M1P9
uniprot id: A0A6J2M1Q5
uniprot id: A0A7E6E214
uniprot id: A0A7E6E3G5
uniprot id: A0A7E6E3H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBP/SF1 family.
messages: Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.
messages: Nucleus

89673:DGAT2L6
gene id: 89673:DGAT2L6
uniprot id: A0A6J2MKL8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:MIDN
gene id: 89673:MIDN
uniprot id: A0A6J2M6I6
uniprot id: A0A6J2M7X1
uniprot id: A0A7E6E9N6
names: Subcellular Location Annotation
messages: Nucleus

89673:POMT1
gene id: 89673:POMT1
uniprot id: A0A6J2MN63
uniprot id: A0A7E6DGY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

89673:IL6
gene id: 89673:IL6
uniprot id: A0A7E6CHJ1
uniprot id: A0A7E6CJI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-6 superfamily.
messages: Component of a hexamer of two molecules each of IL6, IL6R and IL6ST; first binds to IL6R to associate with the signaling subunit IL6ST. Interacts with IL6R (via the N-terminal ectodomain); this interaction may be affected by IL6R-binding with SORL1, hence decreasing IL6 cis signaling. Interacts with SORL1 (via the N-terminal ectodomain); this interaction leads to IL6 internalization and lysosomal degradation. May form a trimeric complex with the soluble SORL1 ectodomain and soluble IL6R receptor; this interaction might stabilize circulating IL6, hence promoting IL6 trans signaling.
messages: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway. The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells.
messages: IL6 is a potent inducer of the acute phase response. Rapid production of IL6 contributes to host defense during infection and tissue injury, but excessive IL6 synthesis is involved in disease pathology. In the innate immune response, is synthesized by myeloid cells, such as macrophages and dendritic cells, upon recognition of pathogens through toll-like receptors (TLRs) at the site of infection or tissue injury (By similarity). In the adaptive immune response, is required for the differentiation of B cells into immunoglobulin-secreting cells. Plays a major role in the differentiation of CD4(+) T cell subsets. Essential factor for the development of T follicular helper (Tfh) cells that are required for the induction of germinal-center formation. Required to drive naive CD4(+) T cells to the Th17 lineage. Also required for proliferation of myeloma cells and the survival of plasmablast cells.
messages: Secreted

89673:YTHDF2
gene id: 89673:YTHDF2
uniprot id: A0A6J2LJB6
uniprot id: A0A6J2LLW9
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

89673:HAPLN4
gene id: 89673:HAPLN4
uniprot id: A0A6J2M900
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

89673:OTUD7A
gene id: 89673:OTUD7A
uniprot id: A0A7E6CPD4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

89673:SPIRE1
gene id: 89673:SPIRE1
uniprot id: A0A6J2MI67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spire family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytoskeleton

89673:CSTA
gene id: 89673:CSTA
uniprot id: A0A6J2KZY9
names: Similarity
messages: Belongs to the cystatin family.

89673:ATP6V1G2
gene id: 89673:ATP6V1G2
uniprot id: A0A6J2LDD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

89673:FGF9
gene id: 89673:FGF9
uniprot id: A0A6J2NGZ9
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

89673:FMO3
gene id: 89673:FMO3
uniprot id: A0A6J2N2Z1
uniprot id: A0A7E6CXN3
uniprot id: A0A7E6CYF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

89673:LOC114500087
gene id: 89673:LOC114500087
uniprot id: A0A6J2M342
uniprot id: A0A7E6DG44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SOSS-C family.
messages: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs).
messages: Component of the SOSS complex.
messages: Nucleus

89673:LOC114508064
gene id: 89673:LOC114508064
uniprot id: A0A6J2MNU3
uniprot id: A0A6J2MQS8
uniprot id: A0A6J2MV74
uniprot id: A0A6J2MVI4
uniprot id: A0A7E6CIP1
names: Similarity
messages: Belongs to the Luc7 family.

89673:DUSP8
gene id: 89673:DUSP8
uniprot id: A0A6J2LV58
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

89673:PPP1R16B
gene id: 89673:PPP1R16B
uniprot id: A0A6J2MLW4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:NLGN2
gene id: 89673:NLGN2
uniprot id: A0A6J2NJ46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

89673:IL1RL2
gene id: 89673:IL1RL2
uniprot id: A0A6J2M1X2
uniprot id: A0A7E6DYE4
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

89673:DPH6
gene id: 89673:DPH6
uniprot id: A0A6J2L8R8
uniprot id: A0A7E6E705
uniprot id: A0A7E6E8U8
uniprot id: A0A7E6E8V5
names: Function
names: Similarity
messages: Amidase that catalyzes the last step of diphthamide biosynthesis using ammonium and ATP.
messages: Belongs to the Diphthine--ammonia ligase family.

89673:GFM2
gene id: 89673:GFM2
uniprot id: A0A6J2KX06
uniprot id: A0A7E6DAE8
uniprot id: A0A7E6DAH5
uniprot id: A0A7E6DAS2
uniprot id: A0A7E6DBK1
uniprot id: A0A7E6DBK6
uniprot id: A0A7E6DD58
uniprot id: A0A7E6DD59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
messages: Mitochondrion

89673:CA11
gene id: 89673:CA11
uniprot id: A0A6J2N1A7
uniprot id: A0A7E6CN72
uniprot id: A0A7E6CN80
uniprot id: A0A7E6CND1
uniprot id: A0A7E6CND9
uniprot id: A0A7E6CQK8
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Does not have a catalytic activity.

89673:MAP2K2
gene id: 89673:MAP2K2
uniprot id: A0A6J2MEL3
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:FOXP4
gene id: 89673:FOXP4
uniprot id: A0A6J2L929
uniprot id: A0A7E6DLI2
uniprot id: A0A7E6DLI3
uniprot id: A0A7E6DLW1
uniprot id: A0A7E6DLZ3
uniprot id: A0A7E6DM94
names: Subcellular Location Annotation
messages: Nucleus

89673:WDFY2
gene id: 89673:WDFY2
uniprot id: A0A6J2MX09
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

89673:TMBIM4
gene id: 89673:TMBIM4
uniprot id: A0A6J2N923
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

89673:ACTR3
gene id: 89673:ACTR3
uniprot id: A0A6J2LEF7
names: Similarity
messages: Belongs to the actin family.

89673:TMCO4
gene id: 89673:TMCO4
uniprot id: A0A6J2LR07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMCO4 family.
messages: Membrane

89673:CTSF
gene id: 89673:CTSF
uniprot id: A0A6J2M1X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

89673:SLC16A3
gene id: 89673:SLC16A3
uniprot id: A0A6J2MC97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

89673:LOC114490329
gene id: 89673:LOC114490329
uniprot id: A0A6J2KY09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:BSX
gene id: 89673:BSX
uniprot id: A0A6J2MU74
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114492577
gene id: 89673:LOC114492577
uniprot id: A0A6J2L4X8
uniprot id: A0A6J2L9N1
uniprot id: A0A7E6DFL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

89673:TFE3
gene id: 89673:TFE3
uniprot id: A0A6J2MFY5
uniprot id: A0A6J2MJ72
uniprot id: A0A7E6D159
uniprot id: A0A7E6D3W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

89673:TMBIM1
gene id: 89673:TMBIM1
uniprot id: A0A6J2LFU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

89673:MARVELD1
gene id: 89673:MARVELD1
uniprot id: A0A6J2LQE3
names: Subcellular Location Annotation
messages: Membrane

89673:RRP8
gene id: 89673:RRP8
uniprot id: A0A6J2M4B7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RRP8 family.
messages: Component of the eNoSC complex.
messages: Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase.
messages: nucleolus

89673:LOC118496670
gene id: 89673:LOC118496670
uniprot id: A0A7E6CD95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

89673:LOC114499033
gene id: 89673:LOC114499033
uniprot id: A0A6J2LUT5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CD37
gene id: 89673:CD37
uniprot id: A0A7E6CNA2
uniprot id: A0A7E6CNA9
uniprot id: A0A7E6CNH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

89673:COQ4
gene id: 89673:COQ4
uniprot id: A0A6J2MHH8
uniprot id: A0A7E6DGU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ4 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.
messages: Mitochondrion inner membrane

89673:LOC114505146
gene id: 89673:LOC114505146
uniprot id: A0A7E6D1D8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

89673:TRPM5
gene id: 89673:TRPM5
uniprot id: A0A7E6E2Y2
names: Subcellular Location Annotation
messages: Membrane

89673:IP6K1
gene id: 89673:IP6K1
uniprot id: A0A6J2M118
uniprot id: A0A7E6E5F4
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

89673:NDUFV1
gene id: 89673:NDUFV1
uniprot id: A0A6J2LY92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 51 kDa subunit family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion inner membrane

89673:SERPINF2
gene id: 89673:SERPINF2
uniprot id: A0A6J2MDC1
names: Similarity
messages: Belongs to the serpin family.

89673:LOC114495272
gene id: 89673:LOC114495272
uniprot id: A0A7E6DHF5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

89673:KCNK4
gene id: 89673:KCNK4
uniprot id: A0A6J2LZL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

89673:LOC114503651
gene id: 89673:LOC114503651
uniprot id: A0A6J2MCT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:RBM15
gene id: 89673:RBM15
uniprot id: A0A6J2KWM1
uniprot id: A0A6J2KYD1
names: Similarity
messages: Belongs to the RRM Spen family.

89673:AP4B1
gene id: 89673:AP4B1
uniprot id: A0A6J2KUH2
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

89673:LOC118499353
gene id: 89673:LOC118499353
uniprot id: A0A7E6D9Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

89673:SLC13A2
gene id: 89673:SLC13A2
uniprot id: A0A6J2M9S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

89673:TACC1
gene id: 89673:TACC1
uniprot id: A0A6J2MTK3
uniprot id: A0A6J2MTL0
uniprot id: A0A6J2MTL5
uniprot id: A0A6J2MY45
uniprot id: A0A6J2MY49
uniprot id: A0A6J2MYK6
uniprot id: A0A6J2MYL2
uniprot id: A0A7E6CKN5
uniprot id: A0A7E6CKN9
uniprot id: A0A7E6CMS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

89673:SERPINI2
gene id: 89673:SERPINI2
uniprot id: A0A6J2L0Z7
names: Similarity
messages: Belongs to the serpin family.

89673:AGBL1
gene id: 89673:AGBL1
uniprot id: A0A7E6CTP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

89673:PRRX2
gene id: 89673:PRRX2
uniprot id: A0A6J2MAD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

89673:LOC114508886
gene id: 89673:LOC114508886
uniprot id: A0A7E6CM34
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.

89673:TLR2
gene id: 89673:TLR2
uniprot id: A0A6J2MAA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
messages: Membrane

89673:TBX10
gene id: 89673:TBX10
uniprot id: A0A7E6E3M5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

89673:QSOX2
gene id: 89673:QSOX2
uniprot id: A0A6J2MID7
names: Function
names: Similarity
messages: Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.
messages: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide.

89673:ZKSCAN2
gene id: 89673:ZKSCAN2
uniprot id: A0A6J2M324
uniprot id: A0A7E6DDZ9
uniprot id: A0A7E6DE16
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

89673:LEO1
gene id: 89673:LEO1
uniprot id: A0A6J2L4F7
uniprot id: A0A6J2L8C8
names: Similarity
messages: Belongs to the LEO1 family.

89673:LOC114499746
gene id: 89673:LOC114499746
uniprot id: A0A6J2LW73
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

89673:SLC10A2
gene id: 89673:SLC10A2
uniprot id: A0A6J2MTA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

89673:NIT2
gene id: 89673:NIT2
uniprot id: A0A6J2L0K8
uniprot id: A0A7E6D3V4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

89673:LOC114496646
gene id: 89673:LOC114496646
uniprot id: A0A6J2LL77
uniprot id: A0A7E6DRW2
uniprot id: A0A7E6DSJ4
uniprot id: A0A7E6DSN1
uniprot id: A0A7E6DT21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

89673:LOC114499060
gene id: 89673:LOC114499060
uniprot id: A0A6J2LSU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CCL16
gene id: 89673:CCL16
uniprot id: A0A6J2MD82
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.

89673:HBQ1
gene id: 89673:HBQ1
uniprot id: A0A6J2MZM6
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: Involved in oxygen transport from the lung to the various peripheral tissues.

89673:CACNG8
gene id: 89673:CACNG8
uniprot id: A0A6J2MZG7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits.

89673:TP53RK
gene id: 89673:TP53RK
uniprot id: A0A6J2MM26
names: Similarity
messages: Belongs to the protein kinase superfamily. BUD32 family.

89673:ACTA1
gene id: 89673:ACTA1
uniprot id: A0A6J2NA43
names: Similarity
messages: Belongs to the actin family.

89673:WNT7A
gene id: 89673:WNT7A
uniprot id: A0A6J2L1X3
uniprot id: A0A7E6D4K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

89673:LOC114506724
gene id: 89673:LOC114506724
uniprot id: A0A6J2MQW7
names: Similarity
messages: Belongs to the cytochrome b5 family.

89673:FAR2
gene id: 89673:FAR2
uniprot id: A0A6J2NGX9
uniprot id: A0A7E6DA17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acyl-CoA reductase family.
messages: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
messages: Peroxisome membrane

89673:PURA
gene id: 89673:PURA
uniprot id: A0A6J2MVF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

89673:PABPC1
gene id: 89673:PABPC1
uniprot id: A0A6J2NIS2
uniprot id: A0A7E6E6J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

89673:LIPM
gene id: 89673:LIPM
uniprot id: A0A6J2LPW4
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

89673:MSL3
gene id: 89673:MSL3
uniprot id: A0A6J2MF78
uniprot id: A0A6J2MHC1
uniprot id: A0A7E6D2B2
names: Subcellular Location Annotation
messages: Nucleus

89673:SOAT1
gene id: 89673:SOAT1
uniprot id: A0A6J2N3Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:LOC114496229
gene id: 89673:LOC114496229
uniprot id: A0A6J2LNE1
names: Similarity
messages: Belongs to the cytochrome P450 family.

89673:PTPN1
gene id: 89673:PTPN1
uniprot id: A0A6J2MMJ8
uniprot id: A0A7E6CFX0
uniprot id: A0A7E6CGD3
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

89673:CLK1
gene id: 89673:CLK1
uniprot id: A0A6J2L9N7
uniprot id: A0A6J2LE84
uniprot id: A0A7E6DJ28
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:GPR156
gene id: 89673:GPR156
uniprot id: A0A6J2L4Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Membrane

89673:HSD17B2
gene id: 89673:HSD17B2
uniprot id: A0A6J2KQX8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

89673:LOC114500362
gene id: 89673:LOC114500362
uniprot id: A0A7E6DW61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL15 family.
messages: Cytoplasm

89673:ORC1
gene id: 89673:ORC1
uniprot id: A0A6J2LIM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC1 family.
messages: Component of ORC, a complex composed of at least 6 subunits: ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. ORC is regulated in a cell-cycle dependent manner. It is sequentially assembled at the exit from anaphase of mitosis and disassembled as cells enter S phase. Interacts with CDC6 and KAT7/HBO1. Interacts with LRWD1 predominantly during the G1 phase and with less affinity during mitosis, when phosphorylated.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Nucleus

89673:MED12
gene id: 89673:MED12
uniprot id: A0A6J2MHS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 12 family.
messages: Nucleus

89673:PAM
gene id: 89673:PAM
uniprot id: A0A6J2LCN0
uniprot id: A0A6J2LD15
uniprot id: A0A6J2LDW0
uniprot id: A0A6J2LE16
uniprot id: A0A6J2LF23
uniprot id: A0A6J2LIJ8
uniprot id: A0A6J2LIP2
uniprot id: A0A7E6DAX3
uniprot id: A0A7E6DB04
uniprot id: A0A7E6DB09
uniprot id: A0A7E6DBB5
uniprot id: A0A7E6DBC0
uniprot id: A0A7E6DC31
uniprot id: A0A7E6DDD0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Binds 2 Cu(2+) ions per subunit.
messages: Binds one Zn(2+) ion per subunit.
messages: In the C-terminal section; belongs to the peptidyl-alpha-hydroxyglycine alpha-amidating lyase family.
messages: In the N-terminal section; belongs to the copper type II ascorbate-dependent monooxygenase family.
messages: Membrane
messages: secretory vesicle membrane

89673:RUNX3
gene id: 89673:RUNX3
uniprot id: A0A6J2LMT5
names: Function
names: Subcellular Location Annotation
messages: Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'-TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
messages: Nucleus

89673:YARS1
gene id: 89673:YARS1
uniprot id: A0A6J2LTR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Nucleus

89673:LOC114500244
gene id: 89673:LOC114500244
uniprot id: A0A6J2M088
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:KCNJ3
gene id: 89673:KCNJ3
uniprot id: A0A6J2LLN4
uniprot id: A0A7E6DK44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
messages: Membrane
messages: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

89673:SEH1L
gene id: 89673:SEH1L
uniprot id: A0A6J2ML67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Lysosome membrane

89673:BCO2
gene id: 89673:BCO2
uniprot id: A0A7E6DZ10
uniprot id: A0A7E6DZI0
uniprot id: A0A7E6E0B6
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

89673:NETO1
gene id: 89673:NETO1
uniprot id: A0A7E6CGG5
uniprot id: A0A7E6CGW0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:RPS7
gene id: 89673:RPS7
uniprot id: A0A6J2M1W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eS7 family.
messages: centrosome

89673:LOC114510638
gene id: 89673:LOC114510638
uniprot id: A0A6J2MZF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:NTN4
gene id: 89673:NTN4
uniprot id: A0A6J2N6J9
uniprot id: A0A7E6DAP4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:SSC5D
gene id: 89673:SSC5D
uniprot id: A0A6J2N6Y3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:JAKMIP1
gene id: 89673:JAKMIP1
uniprot id: A0A6J2L6U4
uniprot id: A0A7E6D5N3
uniprot id: A0A7E6D5P3
names: Similarity
messages: Belongs to the JAKMIP family.

89673:TADA2B
gene id: 89673:TADA2B
uniprot id: A0A6J2LDC9
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC118497679
gene id: 89673:LOC118497679
uniprot id: A0A7E6CPF0
names: Subcellular Location Annotation
messages: Membrane

89673:TAX1BP3
gene id: 89673:TAX1BP3
uniprot id: A0A6J2NJE6
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: May regulate a number of protein-protein interactions by competing for PDZ domain binding sites.
messages: Nucleus

89673:ANK3
gene id: 89673:ANK3
uniprot id: A0A7E6DV96
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

89673:PARP3
gene id: 89673:PARP3
uniprot id: A0A6J2M4Y9
uniprot id: A0A7E6E469
uniprot id: A0A7E6E485
uniprot id: A0A7E6E490
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Nucleus

89673:SNRPE
gene id: 89673:SNRPE
uniprot id: A0A6J2N3X7
uniprot id: A0A7E6CVF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. As part of the U7 snRNP it is involved in histone 3'-end processing.
messages: cytosol

89673:TMCC1
gene id: 89673:TMCC1
uniprot id: A0A6J2M0T1
uniprot id: A0A6J2M252
uniprot id: A0A6J2M2W8
uniprot id: A0A6J2M2X5
uniprot id: A0A6J2M5R9
uniprot id: A0A6J2M5S4
uniprot id: A0A6J2M6C2
names: Similarity
messages: Belongs to the TEX28 family.

89673:TFR2
gene id: 89673:TFR2
uniprot id: A0A6J2NBG1
uniprot id: A0A7E6DDG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

89673:LOC114500439
gene id: 89673:LOC114500439
uniprot id: A0A6J2M4F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:PROCA1
gene id: 89673:PROCA1
uniprot id: A0A6J2ME32
uniprot id: A0A6J2ME72
uniprot id: A0A6J2MHY0
uniprot id: A0A7E6ECA8
uniprot id: A0A7E6EE42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Secreted

89673:LOC114505113
gene id: 89673:LOC114505113
uniprot id: A0A6J2MLI5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:EGFL7
gene id: 89673:EGFL7
uniprot id: A0A7E6DH20
uniprot id: A0A7E6DH47
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:CADM2
gene id: 89673:CADM2
uniprot id: A0A6J2KYJ2
uniprot id: A0A7E6D3N5
uniprot id: A0A7E6D3N9
names: Similarity
messages: Belongs to the nectin family.

89673:LOC114488203
gene id: 89673:LOC114488203
uniprot id: A0A6J2KUE7
uniprot id: A0A7E6CM86
uniprot id: A0A7E6CM88
uniprot id: A0A7E6CM98
uniprot id: A0A7E6CMB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IST1 family.
messages: Cytoplasmic vesicle
messages: Nucleus envelope

89673:SUSD6
gene id: 89673:SUSD6
uniprot id: A0A6J2LD63
uniprot id: A0A7E6CMA7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:BOLA3
gene id: 89673:BOLA3
uniprot id: A0A6J2LYV2
names: Similarity
messages: Belongs to the BolA/IbaG family.

89673:BRIX1
gene id: 89673:BRIX1
uniprot id: A0A6J2M4F5
uniprot id: A0A7E6DAX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRX1 family.
messages: Required for biogenesis of the 60S ribosomal subunit.
messages: nucleolus

89673:LAPTM5
gene id: 89673:LAPTM5
uniprot id: A0A6J2LRD9
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

89673:MTHFR
gene id: 89673:MTHFR
uniprot id: A0A6J2LM08
uniprot id: A0A7E6DPW5
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

89673:HIP1R
gene id: 89673:HIP1R
uniprot id: A0A6J2MZU8
names: Similarity
messages: Belongs to the SLA2 family.

89673:TRMU
gene id: 89673:TRMU
uniprot id: A0A6J2NAZ6
uniprot id: A0A7E6D9I4
names: Function
names: Similarity
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base.

89673:DTX4
gene id: 89673:DTX4
uniprot id: A0A6J2M583
uniprot id: A0A7E6E2X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

89673:NPEPL1
gene id: 89673:NPEPL1
uniprot id: A0A6J2MLL6
names: Similarity
messages: Belongs to the peptidase M17 family.

89673:LOC114503872
gene id: 89673:LOC114503872
uniprot id: A0A7E6EED2
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.

89673:SLC46A3
gene id: 89673:SLC46A3
uniprot id: A0A6J2L5X4
names: Subcellular Location Annotation
messages: Membrane

89673:DERL1
gene id: 89673:DERL1
uniprot id: A0A6J2NCV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Membrane

89673:DPYD
gene id: 89673:DPYD
uniprot id: A0A6J2L0S5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.
messages: Binds 4 [4Fe-4S] clusters. Contains approximately 16 iron atoms per subunit.
messages: Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine.

89673:CNOT6L
gene id: 89673:CNOT6L
uniprot id: A0A6J2L5N6
uniprot id: A0A6J2LAY0
uniprot id: A0A7E6DHF7
uniprot id: A0A7E6DHK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

89673:MPC1L
gene id: 89673:MPC1L
uniprot id: A0A6J2MMX5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

89673:INPP5D
gene id: 89673:INPP5D
uniprot id: A0A7E6DHU6
uniprot id: A0A7E6DHZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.
messages: Membrane

89673:DTNA
gene id: 89673:DTNA
uniprot id: A0A6J2MHP7
uniprot id: A0A6J2MNM7
uniprot id: A0A7E6CDH4
uniprot id: A0A7E6CDH5
uniprot id: A0A7E6CDH8
uniprot id: A0A7E6CDI0
uniprot id: A0A7E6CDI3
uniprot id: A0A7E6CDK4
uniprot id: A0A7E6CDK9
uniprot id: A0A7E6CE80
uniprot id: A0A7E6CE85
uniprot id: A0A7E6CE91
uniprot id: A0A7E6CFU0
uniprot id: A0A7E6CFU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dystrophin family. Dystrobrevin subfamily.
messages: Cytoplasm

89673:LOC114511138
gene id: 89673:LOC114511138
uniprot id: A0A6J2MZJ0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:MAST2
gene id: 89673:MAST2
uniprot id: A0A6J2LHD2
uniprot id: A0A6J2LII6
uniprot id: A0A6J2LJP4
uniprot id: A0A6J2LMB2
uniprot id: A0A7E6DRR3
uniprot id: A0A7E6DRR8
uniprot id: A0A7E6DRS3
uniprot id: A0A7E6DRT6
uniprot id: A0A7E6DRU1
uniprot id: A0A7E6DSE6
uniprot id: A0A7E6DSF3
uniprot id: A0A7E6DSF9
uniprot id: A0A7E6DSI3
uniprot id: A0A7E6DSI7
uniprot id: A0A7E6DSJ1
uniprot id: A0A7E6DSX1
uniprot id: A0A7E6DSX7
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

89673:AMZ2
gene id: 89673:AMZ2
uniprot id: A0A6J2MBY5
uniprot id: A0A6J2MFE0
names: Function
names: Similarity
messages: Belongs to the peptidase M54 family.
messages: Probable zinc metalloprotease.

89673:CLCN7
gene id: 89673:CLCN7
uniprot id: A0A6J2M949
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

89673:SLC24A5
gene id: 89673:SLC24A5
uniprot id: A0A6J2L6T2
uniprot id: A0A7E6EBU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

89673:PCNX2
gene id: 89673:PCNX2
uniprot id: A0A6J2N584
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

89673:PARVB
gene id: 89673:PARVB
uniprot id: A0A6J2N8R9
uniprot id: A0A7E6DBH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parvin family.
messages: Cell membrane

89673:SBF1
gene id: 89673:SBF1
uniprot id: A0A6J2N4Z6
uniprot id: A0A7E6D8R9
uniprot id: A0A7E6D8X2
uniprot id: A0A7E6DBP7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

89673:XKR8
gene id: 89673:XKR8
uniprot id: A0A6J2LPM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

89673:HSPA2
gene id: 89673:HSPA2
uniprot id: A0A6J2L2X1
names: Similarity
messages: Belongs to the heat shock protein 70 family.

89673:HTRA4
gene id: 89673:HTRA4
uniprot id: A0A7E6CKQ7
names: Similarity
messages: Belongs to the peptidase S1C family.

89673:NOP56
gene id: 89673:NOP56
uniprot id: A0A7E6CEX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

89673:RBM8A
gene id: 89673:RBM8A
uniprot id: A0A6J2KWQ6
uniprot id: A0A6J2KYV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RBM8A family.
messages: Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
messages: Cytoplasm
messages: Heterodimer with MAGOH. Part of the mRNA splicing-dependent exon junction complex (EJC) complex; the core complex contains CASC3, EIF4A3, MAGOH and RBM8A.
messages: Nucleus
messages: Nucleus speckle

89673:E2F7
gene id: 89673:E2F7
uniprot id: A0A6J2NB00
uniprot id: A0A7E6D5J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

89673:STXBP5
gene id: 89673:STXBP5
uniprot id: A0A6J2LC40
uniprot id: A0A6J2LFY4
uniprot id: A0A7E6DNK8
uniprot id: A0A7E6DNM1
uniprot id: A0A7E6DP42
uniprot id: A0A7E6DPA1
uniprot id: A0A7E6DPM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat L(2)GL family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

89673:IPO4
gene id: 89673:IPO4
uniprot id: A0A6J2L7J0
uniprot id: A0A7E6E2R5
names: Subcellular Location Annotation
messages: Cytoplasm

89673:RNF8
gene id: 89673:RNF8
uniprot id: A0A6J2LES1
uniprot id: A0A6J2LFQ5
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: According to a well-established model, RNF8 initiate H2A 'Lys-63'-linked ubiquitination leading to recruitment of RNF168 to amplify H2A 'Lys-63'-linked ubiquitination. However, other data suggest that RNF168 is the priming ubiquitin ligase by mediating monoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histone H2A (H2AK13Ub and H2AK15Ub respectively). These data suggest that RNF168 might be recruited to DSBs sites in a RNF8-dependent manner by binding to non-histone proteins ubiquitinated via 'Lys-63'-linked and initiates monoubiquitination of H2A, which is then amplified by RNF8. Additional evidences are however required to confirm these data.
messages: Autoubiquitinated through 'Lys-48' and 'Lys-63' of ubiquitin. 'Lys-63' polyubiquitination is mediated by UBE2N. 'Lys-29'-type polyubiquitination is also observed, but it doesn't require its own functional RING-type zinc finger.
messages: Belongs to the CHFR family.
messages: Belongs to the RNF8 family.
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53BP1 and BRCA1 ionizing radiation-induced foci (IRIF). Also controls the recruitment of UIMC1-BRCC3 (RAP80-BRCC36) and PAXIP1/PTIP to DNA damage sites. Also recruited at DNA interstrand cross-links (ICLs) sites and catalyzes 'Lys-63'-linked ubiquitination of histones H2A and H2AX, leading to recruitment of FAAP20 and Fanconi anemia (FA) complex, followed by interstrand cross-link repair. H2A ubiquitination also mediates the ATM-dependent transcriptional silencing at regions flanking DSBs in cis, a mechanism to avoid collision between transcription and repair intermediates. Promotes the formation of 'Lys-63'-linked polyubiquitin chains via interactions with the specific ubiquitin-conjugating UBE2N/UBC13 and ubiquitinates non-histone substrates such as PCNA. Substrates that are polyubiquitinated at 'Lys-63' are usually not targeted for degradation. Also catalyzes the formation of 'Lys-48'-linked polyubiquitin chains via interaction with the ubiquitin-conjugating UBE2L6/UBCH8, leading to degradation of substrate proteins such as CHEK2, JMJD2A/KDM4A and KU80/XRCC5: it is still unclear how the preference toward 'Lys-48'- versus 'Lys-63'-linked ubiquitination is regulated but it could be due to RNF8 ability to interact with specific E2 specific ligases. For instance, interaction with phosphorylated HERC2 promotes the association between RNF8 and UBE2N/UBC13 and favors the specific formation of 'Lys-63'-linked ubiquitin chains…
messages: Homodimer. Forms a E2-E3 ubiquitin ligase complex composed of the RNF8 homodimer and a E2 heterodimer of UBE2N and UBE2V2. Interacts with class III E2s, including UBE2E1, UBE2E2, and UBE2E3 and with UBE2N. Interacts with RXRA. Interacts (via FHA domain) with phosphorylated HERC2 (via C-terminus). Interacts with PIWIL1; leading to sequester RNF8 in the cytoplasm.
messages: Midbody
messages: Nucleus
messages: The FHA domain specifically recognizes and binds ATM-phosphorylated MDC1 and phosphorylated HERC2.
messages: telomere

89673:CCNA2
gene id: 89673:CCNA2
uniprot id: A0A6J2MB43
uniprot id: A0A7E6E9Q7
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

89673:PPT1
gene id: 89673:PPT1
uniprot id: A0A6J2LQM7
names: Similarity
messages: Belongs to the palmitoyl-protein thioesterase family.

89673:LOC114500121
gene id: 89673:LOC114500121
uniprot id: A0A6J2LZQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:IFRD2
gene id: 89673:IFRD2
uniprot id: A0A6J2M6N5
names: Similarity
messages: Belongs to the IFRD family.

89673:LAMP2
gene id: 89673:LAMP2
uniprot id: A0A6J2MD67
uniprot id: A0A6J2MFB3
uniprot id: A0A6J2MIH9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lysosome membrane
messages: Membrane

89673:SEMA5B
gene id: 89673:SEMA5B
uniprot id: A0A6J2L2K1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114489037
gene id: 89673:LOC114489037
uniprot id: A0A7E6CYE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

89673:KRT10
gene id: 89673:KRT10
uniprot id: A0A7E6EDV1
uniprot id: A0A7E6EEG1
uniprot id: A0A7E6EEL6
uniprot id: A0A7E6EEM4
names: Similarity
messages: Belongs to the intermediate filament family.

89673:CDC25B
gene id: 89673:CDC25B
uniprot id: A0A6J2MLY5
uniprot id: A0A7E6CER8
uniprot id: A0A7E6CES7
uniprot id: A0A7E6CFF1
uniprot id: A0A7E6CGZ6
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

89673:ATG4C
gene id: 89673:ATG4C
uniprot id: A0A7E6DTJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

89673:LOC114513292
gene id: 89673:LOC114513292
uniprot id: A0A6J2N732
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

89673:LCN9
gene id: 89673:LCN9
uniprot id: A0A7E6D9R7
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

89673:HNF1B
gene id: 89673:HNF1B
uniprot id: A0A6J2M9P7
uniprot id: A0A6J2MCH0
uniprot id: A0A6J2MD22
uniprot id: A0A7E6EDS9
uniprot id: A0A7E6EES2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HNF1 homeobox family.
messages: Nucleus

89673:ATP5MC2
gene id: 89673:ATP5MC2
uniprot id: A0A6J2N784
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

89673:USP2
gene id: 89673:USP2
uniprot id: A0A6J2LWM7
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

89673:SLC18B1
gene id: 89673:SLC18B1
uniprot id: A0A6J2LC94
names: Subcellular Location Annotation
messages: Membrane

89673:CXCR3
gene id: 89673:CXCR3
uniprot id: A0A7E6CZK1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Homomer. Forms heteromers with ACKR4.
messages: Membrane

89673:NARF
gene id: 89673:NARF
uniprot id: A0A6J2MDT0
names: Similarity
messages: Belongs to the NARF family.

89673:PNPT1
gene id: 89673:PNPT1
uniprot id: A0A6J2LVP0
uniprot id: A0A7E6DYB4
names: Similarity
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.

89673:CORO2B
gene id: 89673:CORO2B
uniprot id: A0A6J2L8X7
uniprot id: A0A6J2LD17
names: Similarity
messages: Belongs to the WD repeat coronin family.

89673:GABRA5
gene id: 89673:GABRA5
uniprot id: A0A6J2KZJ0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

89673:KIF1A
gene id: 89673:KIF1A
uniprot id: A0A7E6DHQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: axon

89673:SNCG
gene id: 89673:SNCG
uniprot id: A0A6J2LM60
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synuclein family.
messages: May be a centrosome-associated protein. Interacts with MYOC; affects its secretion and its aggregation.
messages: spindle

89673:LOC114500657
gene id: 89673:LOC114500657
uniprot id: A0A6J2M1Q4
names: Subcellular Location Annotation
messages: Secreted

89673:PTPRZ1
gene id: 89673:PTPRZ1
uniprot id: A0A6J2MMG8
uniprot id: A0A6J2MPE0
uniprot id: A0A6J2MTQ2
uniprot id: A0A6J2MTY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily.
messages: Membrane

89673:FSCN1
gene id: 89673:FSCN1
uniprot id: A0A6J2MU57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

89673:LOC114499990
gene id: 89673:LOC114499990
uniprot id: A0A6J2M2B0
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

89673:LOC114509950
gene id: 89673:LOC114509950
uniprot id: A0A6J2MXQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:UHRF2
gene id: 89673:UHRF2
uniprot id: A0A6J2MYV6
uniprot id: A0A7E6DEU3
uniprot id: A0A7E6DEW4
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Multi domain E3 ubiquitin ligase that also plays a role in DNA methylation and histone modifications.
messages: Nucleus
messages: The YDG domain mediates the interaction with histone H3.
messages: The tudor-like regions specifically recognize and bind histone H3 unmethylated at 'Arg-2' (H3R2me0), while the PHD-type zinc finger specifically recognizes and binds histone H3 trimethylated at 'Lys-9' (H3K9me3).

89673:STXBP3
gene id: 89673:STXBP3
uniprot id: A0A6J2KXD5
uniprot id: A0A7E6CXW8
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

89673:LOC114509416
gene id: 89673:LOC114509416
uniprot id: A0A7E6CSE0
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

89673:NEXMIF
gene id: 89673:NEXMIF
uniprot id: A0A6J2MFJ8
names: Subcellular Location Annotation
messages: Nucleus

89673:MEX3A
gene id: 89673:MEX3A
uniprot id: A0A6J2KSR1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

89673:FUT4
gene id: 89673:FUT4
uniprot id: A0A7E6DZR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

89673:SIRT5
gene id: 89673:SIRT5
uniprot id: A0A6J2LUZ3
uniprot id: A0A7E6DTR5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: In contrast to class I sirtuins, class III sirtuins have only weak deacetylase activity. Difference in substrate specificity is probably due to a larger hydrophobic pocket with 2 residues (Tyr-102 and Arg-105) that bind to malonylated and succinylated substrates and define the specificity.
messages: In contrast to class I sirtuins, class III sirtuins have only weak deacetylase activity. Difference in substrate specificity is probably due to a larger hydrophobic pocket with 2 residues (Tyr-63 and Arg-66) that bind to malonylated and succinylated substrates and define the specificity.
messages: Mitochondrion
messages: Monomer. Homodimer. Interacts with CPS1.
messages: NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinylation and activation of HMGCS2. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro such as Uox.
messages: Nucleus
messages: cytosol

89673:RIC3
gene id: 89673:RIC3
uniprot id: A0A6J2LYJ3
names: Similarity
messages: Belongs to the ric-3 family.

89673:LOC114514587
gene id: 89673:LOC114514587
uniprot id: A0A6J2NAS8
uniprot id: A0A6J2NHM7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:MPI
gene id: 89673:MPI
uniprot id: A0A6J2L5C3
uniprot id: A0A7E6DWZ1
uniprot id: A0A7E6DX42
uniprot id: A0A7E6DXF8
uniprot id: A0A7E6DXH7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

89673:NOXA1
gene id: 89673:NOXA1
uniprot id: A0A7E6D9N0
names: Similarity
messages: Belongs to the NCF2/NOXA1 family.

89673:CLN3
gene id: 89673:CLN3
uniprot id: A0A7E6DD11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the battenin family.
messages: Lysosome membrane
messages: Membrane

89673:LOC114494580
gene id: 89673:LOC114494580
uniprot id: A0A6J2LCZ0
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

89673:TICAM1
gene id: 89673:TICAM1
uniprot id: A0A6J2M770
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer. Found in a multi-helicase-TICAM1 complex at least composed of DHX36, DDX1, DDX21 and TICAM1.
messages: Involved in innate immunity against invading pathogens. Adapter used by TLR3, TLR4 (through TICAM2) and TLR5 to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively. Phosphorylation by TBK1 on the pLxIS motif leads to recruitment and subsequent activation of the transcription factor IRF3 to induce expression of type I interferon and exert a potent immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of pro-inflammatory cytokines.
messages: Mitochondrion
messages: The N-terminal region is essential for activation of the IFNB promoter activity.
messages: autophagosome
messages: cytosol

89673:LOC114507861
gene id: 89673:LOC114507861
uniprot id: A0A6J2MUQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CCR9
gene id: 89673:CCR9
uniprot id: A0A6J2M571
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:PRPF4B
gene id: 89673:PRPF4B
uniprot id: A0A6J2LNA8
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.
messages: Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF.

89673:SDHAF3
gene id: 89673:SDHAF3
uniprot id: A0A7E6CJQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I LYR family. SDHAF3 subfamily.
messages: Interacts with the iron-sulfur protein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.

89673:AMPD3
gene id: 89673:AMPD3
uniprot id: A0A6J2LWD3
uniprot id: A0A7E6E0A1
uniprot id: A0A7E6E0G2
uniprot id: A0A7E6E0G8
uniprot id: A0A7E6E0T6
uniprot id: A0A7E6E1I8
uniprot id: A0A7E6E1J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
messages: Cell junction
messages: Cell membrane
messages: Cytoplasmic vesicle lumen

89673:HAP1
gene id: 89673:HAP1
uniprot id: A0A6J2M8B2
names: Subcellular Location Annotation
messages: Early endosome
messages: Mitochondrion

89673:MAP2
gene id: 89673:MAP2
uniprot id: A0A6J2L9G7
uniprot id: A0A6J2L9H5
uniprot id: A0A6J2L9I0
uniprot id: A0A6J2L9I6
uniprot id: A0A6J2LA16
uniprot id: A0A6J2LA21
uniprot id: A0A6J2LA26
uniprot id: A0A6J2LF65
uniprot id: A0A7E6DIB4
uniprot id: A0A7E6DIC0
uniprot id: A0A7E6DIC5
uniprot id: A0A7E6DID5
uniprot id: A0A7E6DIE2
uniprot id: A0A7E6DIE6
uniprot id: A0A7E6DIE8
uniprot id: A0A7E6DIF0
uniprot id: A0A7E6DIG0
uniprot id: A0A7E6DIG5
uniprot id: A0A7E6DIH0
uniprot id: A0A7E6DIJ5
uniprot id: A0A7E6DIJ6
uniprot id: A0A7E6DIK0
uniprot id: A0A7E6DIK1
uniprot id: A0A7E6DIK5
uniprot id: A0A7E6DIK6
uniprot id: A0A7E6DIL6
uniprot id: A0A7E6DIM1
uniprot id: A0A7E6DIM4
uniprot id: A0A7E6DIM7
uniprot id: A0A7E6DIN9
uniprot id: A0A7E6DIP4
uniprot id: A0A7E6DIQ0
uniprot id: A0A7E6DIQ8
uniprot id: A0A7E6DIR3
names: Subcellular Location Annotation
messages: cytoskeleton

89673:PNCK
gene id: 89673:PNCK
uniprot id: A0A6J2MFI6
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:IL12B
gene id: 89673:IL12B
uniprot id: A0A6J2N2T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-12B family.
messages: Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.
messages: Heterodimer with IL12A; disulfide-linked. The heterodimer is known as interleukin IL-12. Heterodimer with IL23A; disulfide-linked. The heterodimer is known as interleukin IL-23. Also secreted as a monomer. Interacts with NBR1; this interaction promotes IL-12 secretion.
messages: Secreted

89673:LGSN
gene id: 89673:LGSN
uniprot id: A0A6J2LL82
uniprot id: A0A7E6DM35
uniprot id: A0A7E6DML5
uniprot id: A0A7E6DMW4
names: Similarity
messages: Belongs to the glutamine synthetase family.

89673:ANXA3
gene id: 89673:ANXA3
uniprot id: A0A6J2L9J8
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

89673:FTCD
gene id: 89673:FTCD
uniprot id: A0A6J2L1K2
uniprot id: A0A7E6D2B3
uniprot id: A0A7E6D563
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds and promotes bundling of vimentin filaments originating from the Golgi.
messages: Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool.
messages: Golgi apparatus
messages: Homooctamer, including four polyglutamate binding sites. The subunits are arranged as a tetramer of dimers, and form a planar ring-shaped structure.
messages: In the C-terminal section; belongs to the cyclodeaminase/cyclohydrolase family.
messages: In the N-terminal section; belongs to the formiminotransferase family.
messages: centriole

89673:KBTBD8
gene id: 89673:KBTBD8
uniprot id: A0A6J2M3J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KBTBD8 family.
messages: Golgi apparatus
messages: spindle

89673:PIGW
gene id: 89673:PIGW
uniprot id: A0A6J2MEL1
uniprot id: A0A7E6ED38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGW family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.

89673:GATA3
gene id: 89673:GATA3
uniprot id: A0A6J2L3N2
uniprot id: A0A6J2L888
names: Subcellular Location Annotation
messages: Nucleus

89673:MS4A1
gene id: 89673:MS4A1
uniprot id: A0A6J2LZ65
uniprot id: A0A7E6E1I0
names: Similarity
messages: Belongs to the MS4A family.

89673:SRP9
gene id: 89673:SRP9
uniprot id: A0A6J2NAR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP9 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm

89673:LOC114505480
gene id: 89673:LOC114505480
uniprot id: A0A6J2MMP8
names: Similarity
messages: Belongs to the pro/parathymosin family.

89673:KRT18
gene id: 89673:KRT18
uniprot id: A0A6J2NAY5
names: Similarity
messages: Belongs to the intermediate filament family.

89673:VXN
gene id: 89673:VXN
uniprot id: A0A6J2NDJ0
uniprot id: A0A6J2NIV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vexin family.
messages: Cell membrane
messages: Membrane
messages: Nucleus

89673:CETN2
gene id: 89673:CETN2
uniprot id: A0A6J2MG93
names: Similarity
messages: Belongs to the centrin family.

89673:LOC114490131
gene id: 89673:LOC114490131
uniprot id: A0A6J2L2L6
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.

89673:PCSK6
gene id: 89673:PCSK6
uniprot id: A0A7E6CPE9
names: Similarity
messages: Belongs to the peptidase S8 family.

89673:CRYBB1
gene id: 89673:CRYBB1
uniprot id: A0A6J2N197
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

89673:ATP8A2
gene id: 89673:ATP8A2
uniprot id: A0A7E6D4R0
uniprot id: A0A7E6D4U3
uniprot id: A0A7E6D5B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

89673:SLC9A3
gene id: 89673:SLC9A3
uniprot id: A0A6J2ND48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Membrane
messages: Recycling endosome membrane

89673:PDE9A
gene id: 89673:PDE9A
uniprot id: A0A6J2L0D8
uniprot id: A0A7E6D263
uniprot id: A0A7E6D284
uniprot id: A0A7E6D518
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

89673:LOC114507395
gene id: 89673:LOC114507395
uniprot id: A0A6J2MSW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TBC1D23
gene id: 89673:TBC1D23
uniprot id: A0A6J2L0E8
uniprot id: A0A6J2L2E0
uniprot id: A0A7E6D3U2
uniprot id: A0A7E6D6I1
names: Subcellular Location Annotation
messages: trans-Golgi network

89673:TMEM50A
gene id: 89673:TMEM50A
uniprot id: A0A6J2LLC8
uniprot id: A0A7E6DR73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

89673:KCNJ5
gene id: 89673:KCNJ5
uniprot id: A0A6J2MXA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ5 subfamily.
messages: Membrane

89673:LOC114508039
gene id: 89673:LOC114508039
uniprot id: A0A7E6CIE3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

89673:PDK2
gene id: 89673:PDK2
uniprot id: A0A6J2MD51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

89673:CBWD3
gene id: 89673:CBWD3
uniprot id: A0A6J2MGU1
uniprot id: A0A7E6DF02
uniprot id: A0A7E6DF04
uniprot id: A0A7E6DF07
uniprot id: A0A7E6DF31
uniprot id: A0A7E6DF34
uniprot id: A0A7E6DF45
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

89673:HABP4
gene id: 89673:HABP4
uniprot id: A0A6J2NBJ5
uniprot id: A0A7E6DEE7
names: Similarity
messages: Belongs to the SERBP1-HABP4 family.

89673:CLDN6
gene id: 89673:CLDN6
uniprot id: A0A6J2LLK1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

89673:LOC114491008
gene id: 89673:LOC114491008
uniprot id: A0A6J2L242
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

89673:SLC1A4
gene id: 89673:SLC1A4
uniprot id: A0A6J2LX75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

89673:LOC114503643
gene id: 89673:LOC114503643
uniprot id: A0A6J2MCQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114507470
gene id: 89673:LOC114507470
uniprot id: A0A6J2MLP6
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

89673:ITGA2
gene id: 89673:ITGA2
uniprot id: A0A7E6D9P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

89673:CDH4
gene id: 89673:CDH4
uniprot id: A0A7E6CGG7
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

89673:PDCL3
gene id: 89673:PDCL3
uniprot id: A0A6J2LWJ7
names: Similarity
messages: Belongs to the phosducin family.

89673:MYO1D
gene id: 89673:MYO1D
uniprot id: A0A6J2M886
uniprot id: A0A7E6ED32
uniprot id: A0A7E6EEA2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

89673:PFDN5
gene id: 89673:PFDN5
uniprot id: A0A6J2N8C1
uniprot id: A0A7E6D6D6
names: Similarity
messages: Belongs to the prefoldin subunit alpha family.

89673:MYO15B
gene id: 89673:MYO15B
uniprot id: A0A7E6CD88
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

89673:LTBP3
gene id: 89673:LTBP3
uniprot id: A0A6J2LZZ2
uniprot id: A0A7E6E3G7
uniprot id: A0A7E6E4Z2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

89673:METTL6
gene id: 89673:METTL6
uniprot id: A0A6J2M388
uniprot id: A0A6J2M420
uniprot id: A0A7E6E574
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

89673:LOC114494267
gene id: 89673:LOC114494267
uniprot id: A0A6J2LG71
names: Similarity
messages: Belongs to the histone H3 family.

89673:INPP5A
gene id: 89673:INPP5A
uniprot id: A0A6J2LL75
uniprot id: A0A7E6DVU7
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family.

89673:CHAF1A
gene id: 89673:CHAF1A
uniprot id: A0A6J2M9C3
uniprot id: A0A7E6E9R5
uniprot id: A0A7E6EAZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CHAF1A family.
messages: Nucleus

89673:DUOX1
gene id: 89673:DUOX1
uniprot id: A0A6J2L8Z4
uniprot id: A0A7E6ECB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.
messages: In the N-terminal section; belongs to the peroxidase family.
messages: Membrane

89673:ADGRF1
gene id: 89673:ADGRF1
uniprot id: A0A6J2LEB1
uniprot id: A0A7E6DM67
uniprot id: A0A7E6DMA7
uniprot id: A0A7E6DMJ0
names: Subcellular Location Annotation
messages: Membrane

89673:PTCH1
gene id: 89673:PTCH1
uniprot id: A0A6J2N498
uniprot id: A0A6J2N632
uniprot id: A0A7E6DEA4
uniprot id: A0A7E6DED0
uniprot id: A0A7E6DED4
uniprot id: A0A7E6DEE4
uniprot id: A0A7E6DEE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

89673:LOC114510923
gene id: 89673:LOC114510923
uniprot id: A0A7E6CQI9
uniprot id: A0A7E6CQV1
uniprot id: A0A7E6CQV5
uniprot id: A0A7E6CT42
names: Similarity
messages: Belongs to the MHC class I family.

89673:TCF7L2
gene id: 89673:TCF7L2
uniprot id: A0A6J2LK51
uniprot id: A0A6J2LK56
uniprot id: A0A6J2LK67
uniprot id: A0A6J2LLE0
uniprot id: A0A6J2LLE5
uniprot id: A0A6J2LMF2
uniprot id: A0A6J2LMF7
uniprot id: A0A6J2LQ88
uniprot id: A0A6J2LQA1
uniprot id: A0A6J2LQA8
uniprot id: A0A6J2LQJ6
uniprot id: A0A6J2LQK5
uniprot id: A0A6J2LQL0
uniprot id: A0A7E6DVD6
uniprot id: A0A7E6DVE4
uniprot id: A0A7E6DVE9
uniprot id: A0A7E6DVF3
uniprot id: A0A7E6DVF8
uniprot id: A0A7E6DVJ9
uniprot id: A0A7E6DVK4
uniprot id: A0A7E6DVL1
uniprot id: A0A7E6DVL6
uniprot id: A0A7E6DW00
uniprot id: A0A7E6DW06
uniprot id: A0A7E6DW11
uniprot id: A0A7E6DW15
uniprot id: A0A7E6DW20
uniprot id: A0A7E6DW24
uniprot id: A0A7E6DWC6
uniprot id: A0A7E6DWD1
uniprot id: A0A7E6DWE3
uniprot id: A0A7E6DWE8
uniprot id: A0A7E6DWT0
uniprot id: A0A7E6DWT3
uniprot id: A0A7E6DWT8
uniprot id: A0A7E6DWU4
uniprot id: A0A7E6DWU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

89673:LOC114491701
gene id: 89673:LOC114491701
uniprot id: A0A6J2L2Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFamide neuropeptide family.
messages: Secreted

89673:BTNL9
gene id: 89673:BTNL9
uniprot id: A0A7E6CSN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

89673:ADGRF2
gene id: 89673:ADGRF2
uniprot id: A0A6J2LIU2
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114505301
gene id: 89673:LOC114505301
uniprot id: A0A6J2MHQ5
names: Similarity
messages: Belongs to the histone H3 family.

89673:HOXB2
gene id: 89673:HOXB2
uniprot id: A0A6J2MH56
uniprot id: A0A7E6EFF7
names: Subcellular Location Annotation
messages: Nucleus

89673:CPPED1
gene id: 89673:CPPED1
uniprot id: A0A6J2MRU4
names: Function
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. CPPED1 family.
messages: Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. May play an inhibitory role in glucose uptake by adipocytes.

89673:LOC114489505
gene id: 89673:LOC114489505
uniprot id: A0A6J2KUL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:LOC114513663
gene id: 89673:LOC114513663
uniprot id: A0A6J2NFB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ataxin-10 family.
messages: Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis.
messages: perinuclear region

89673:TIMM21
gene id: 89673:TIMM21
uniprot id: A0A6J2MR32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM21 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane
messages: Participates in the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Also required for assembly of mitochondrial respiratory chain complex I and complex IV as component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex. Probably shuttles between the presequence translocase and respiratory-chain assembly intermediates in a process that promotes incorporation of early nuclear-encoded subunits into these complexes.

89673:LOC114515180
gene id: 89673:LOC114515180
uniprot id: A0A6J2NCS4
names: Similarity
messages: Belongs to the actin family.

89673:PI4KB
gene id: 89673:PI4KB
uniprot id: A0A6J2KSM6
uniprot id: A0A6J2KT81
uniprot id: A0A6J2KYM0
uniprot id: A0A6J2KYM6
uniprot id: A0A7E6CW56
uniprot id: A0A7E6CYR5
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

89673:WASHC1
gene id: 89673:WASHC1
uniprot id: A0A7E6D560
uniprot id: A0A7E6D824
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WASH1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Recycling endosome membrane

89673:ELOC
gene id: 89673:ELOC
uniprot id: A0A6J2M4E5
names: Similarity
messages: Belongs to the SKP1 family.

89673:NDUFC1
gene id: 89673:NDUFC1
uniprot id: A0A6J2MBT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFC1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

89673:RHOT2
gene id: 89673:RHOT2
uniprot id: A0A6J2MBM0
uniprot id: A0A6J2MEJ9
uniprot id: A0A7E6DCI4
uniprot id: A0A7E6DDN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking.
messages: Mitochondrion outer membrane

89673:PIGX
gene id: 89673:PIGX
uniprot id: A0A7E6CZF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGX family.
messages: Endoplasmic reticulum membrane
messages: Essential component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis.

89673:CSTF1
gene id: 89673:CSTF1
uniprot id: A0A6J2MIX1
names: Subcellular Location Annotation
messages: Nucleus

89673:KIF1C
gene id: 89673:KIF1C
uniprot id: A0A6J2NJV9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

89673:ACADS
gene id: 89673:ACADS
uniprot id: A0A6J2N3I0
uniprot id: A0A7E6CUN1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

89673:SWI5
gene id: 89673:SWI5
uniprot id: A0A7E6DGJ9
names: Function
names: Similarity
messages: Belongs to the SWI5/SAE3 family.
messages: Component of the swi5-sfr1 complex, a complex required for double-strand break repair via homologous recombination.

89673:EHF
gene id: 89673:EHF
uniprot id: A0A6J2M5I6
uniprot id: A0A7E6E0S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

89673:NOX3
gene id: 89673:NOX3
uniprot id: A0A6J2LLD0
names: Subcellular Location Annotation
messages: Membrane

89673:CFL2
gene id: 89673:CFL2
uniprot id: A0A6J2L4H5
uniprot id: A0A6J2L7X7
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

89673:ADGRG2
gene id: 89673:ADGRG2
uniprot id: A0A6J2MD31
uniprot id: A0A6J2MF68
uniprot id: A0A6J2MF81
uniprot id: A0A7E6D0M7
uniprot id: A0A7E6D0N2
uniprot id: A0A7E6D0Q2
uniprot id: A0A7E6D0Q9
uniprot id: A0A7E6D0V7
uniprot id: A0A7E6D1K9
uniprot id: A0A7E6D3G8
uniprot id: A0A7E6D3H3
names: Subcellular Location Annotation
messages: Membrane

89673:MACF1
gene id: 89673:MACF1
uniprot id: A0A7E6DXA9
names: Subcellular Location Annotation
messages: cytoskeleton

89673:FXYD4
gene id: 89673:FXYD4
uniprot id: A0A6J2LHW3
uniprot id: A0A7E6DUW4
names: Similarity
messages: Belongs to the FXYD family.

89673:SMC3
gene id: 89673:SMC3
uniprot id: A0A6J2LJN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC3 subfamily.
messages: Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex also plays an important role in spindle pole assembly during mitosis and in chromosomes movement.
messages: Nucleus
messages: centromere

89673:LOC114499010
gene id: 89673:LOC114499010
uniprot id: A0A6J2LUR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:FBN2
gene id: 89673:FBN2
uniprot id: A0A6J2L3J9
uniprot id: A0A7E6DB67
uniprot id: A0A7E6DCE7
uniprot id: A0A7E6DDF6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fibrillin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

89673:YPEL1
gene id: 89673:YPEL1
uniprot id: A0A6J2N2H4
names: Similarity
messages: Belongs to the yippee family.

89673:ENTPD3
gene id: 89673:ENTPD3
uniprot id: A0A6J2M804
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

89673:APPL1
gene id: 89673:APPL1
uniprot id: A0A6J2M2J2
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: Nucleus
messages: phagosome
messages: ruffle

89673:CHMP4C
gene id: 89673:CHMP4C
uniprot id: A0A6J2M7S2
names: Similarity
messages: Belongs to the SNF7 family.

89673:AGAP3
gene id: 89673:AGAP3
uniprot id: A0A6J2MM83
uniprot id: A0A6J2MTG4
uniprot id: A0A7E6CJ39
uniprot id: A0A7E6CJ60
uniprot id: A0A7E6CJ80
uniprot id: A0A7E6CJC0
names: Similarity
messages: Belongs to the centaurin gamma-like family.

89673:EEF1AKMT2
gene id: 89673:EEF1AKMT2
uniprot id: A0A6J2LNB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.
messages: Cytoplasm
messages: Nucleus
messages: Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'.

89673:FGF21
gene id: 89673:FGF21
uniprot id: A0A6J2N576
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

89673:CPE
gene id: 89673:CPE
uniprot id: A0A6J2MAL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M14 family.
messages: Interacts with Secretogranin III/SCG3.
messages: Membrane
messages: Sorting receptor that directs prohormones to the regulated secretory pathway. Acts also as a prohormone processing enzyme in neuro/endocrine cells, removing dibasic residues from the C-terminal end of peptide hormone precursors after initial endoprotease cleavage.
messages: secretory vesicle membrane

89673:LOC114505527
gene id: 89673:LOC114505527
uniprot id: A0A7E6D1K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Nucleus

89673:PPP1R15B
gene id: 89673:PPP1R15B
uniprot id: A0A6J2N3M0
uniprot id: A0A6J2N890
names: Similarity
messages: Belongs to the PPP1R15 family.

89673:CELF5
gene id: 89673:CELF5
uniprot id: A0A6J2M4T1
uniprot id: A0A7E6EF46
uniprot id: A0A7E6EFN5
uniprot id: A0A7E6EFZ8
uniprot id: A0A7E6EGX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Nucleus

89673:GPHB5
gene id: 89673:GPHB5
uniprot id: A0A6J2L353
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

89673:GTF2B
gene id: 89673:GTF2B
uniprot id: A0A6J2LSD3
names: Similarity
messages: Belongs to the TFIIB family.

89673:LOC114510478
gene id: 89673:LOC114510478
uniprot id: A0A7E6DC33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND2 (condensin subunit 2) family.
messages: Chromosome
messages: Cytoplasm
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.

89673:INTS7
gene id: 89673:INTS7
uniprot id: A0A6J2N3V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 7 family.
messages: Nucleus

89673:RASGRP1
gene id: 89673:RASGRP1
uniprot id: A0A6J2L7L9
uniprot id: A0A7E6E8U5
names: Similarity
messages: Belongs to the RASGRP family.

89673:LOC114513013
gene id: 89673:LOC114513013
uniprot id: A0A6J2NCJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

89673:VIRMA
gene id: 89673:VIRMA
uniprot id: A0A6J2NDH5
uniprot id: A0A6J2NI92
names: Similarity
messages: Belongs to the vir family.

89673:FGB
gene id: 89673:FGB
uniprot id: A0A7E6EA46
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

89673:ACSS3
gene id: 89673:ACSS3
uniprot id: A0A6J2NFP6
uniprot id: A0A7E6D5K7
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

89673:FAM118B
gene id: 89673:FAM118B
uniprot id: A0A6J2N3Q9
names: Similarity
messages: Belongs to the FAM118 family.

89673:LSM14A
gene id: 89673:LSM14A
uniprot id: A0A6J2MY69
uniprot id: A0A6J2MZU2
uniprot id: A0A6J2N4H9
uniprot id: A0A6J2N4I4
names: Similarity
messages: Belongs to the LSM14 family.

89673:PPP2CB
gene id: 89673:PPP2CB
uniprot id: A0A6J2MT60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family.
messages: Cytoplasm

89673:ADD3
gene id: 89673:ADD3
uniprot id: A0A6J2LIH7
uniprot id: A0A6J2LN02
uniprot id: A0A7E6DVB5
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

89673:LOC114489502
gene id: 89673:LOC114489502
uniprot id: A0A7E6CVR8
names: Similarity
messages: Belongs to the histone H3 family.

89673:IRF8
gene id: 89673:IRF8
uniprot id: A0A6J2KTI2
names: Subcellular Location Annotation
messages: Nucleus

89673:PDGFRA
gene id: 89673:PDGFRA
uniprot id: A0A6J2L7S5
uniprot id: A0A7E6DAR9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Interacts with homodimeric PDGFA, PDGFB and PDGFC, and with heterodimers formed by PDGFA and PDGFB. Monomer in the absence of bound ligand.
messages: Membrane
messages: Present in an inactive conformation in the absence of bound ligand. Binding of PDGFA and/or PDGFB leads to dimerization and activation by autophosphorylation on tyrosine residues.
messages: Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.

89673:CCDC181
gene id: 89673:CCDC181
uniprot id: A0A6J2N2T8
uniprot id: A0A6J2N2U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC181 family.
messages: Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids.
messages: cytoskeleton

89673:FSIP1
gene id: 89673:FSIP1
uniprot id: A0A6J2LCB0
names: Similarity
messages: Belongs to the FSIP1 family.

89673:LOC114513491
gene id: 89673:LOC114513491
uniprot id: A0A6J2N7U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:MON1B
gene id: 89673:MON1B
uniprot id: A0A6J2KQP8
uniprot id: A0A6J2KUM5
names: Function
names: Similarity
messages: Belongs to the MON1/SAND family.
messages: Plays an important role in membrane trafficking through the secretory apparatus.

89673:DHRS7
gene id: 89673:DHRS7
uniprot id: A0A6J2L8M0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

89673:LOC114500996
gene id: 89673:LOC114500996
uniprot id: A0A6J2M2M6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ADH5
gene id: 89673:ADH5
uniprot id: A0A6J2L3X1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

89673:ARTN
gene id: 89673:ARTN
uniprot id: A0A6J2LV97
uniprot id: A0A7E6DRJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

89673:LOC114508100
gene id: 89673:LOC114508100
uniprot id: A0A7E6CHG2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space
messages: Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

89673:PAQR5
gene id: 89673:PAQR5
uniprot id: A0A6J2L5W8
uniprot id: A0A7E6CF80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

89673:TMTC1
gene id: 89673:TMTC1
uniprot id: A0A6J2N9J9
uniprot id: A0A7E6D7U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

89673:GAL3ST2
gene id: 89673:GAL3ST2
uniprot id: A0A7E6DHF1
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

89673:LOC114503378
gene id: 89673:LOC114503378
uniprot id: A0A6J2MBU6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TMPRSS3
gene id: 89673:TMPRSS3
uniprot id: A0A6J2L1B5
uniprot id: A0A6J2L352
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:FAM216A
gene id: 89673:FAM216A
uniprot id: A0A6J2MVK0
uniprot id: A0A7E6CS25
uniprot id: A0A7E6CSA7
names: Similarity
messages: Belongs to the FAM216 family.

89673:ZC2HC1C
gene id: 89673:ZC2HC1C
uniprot id: A0A6J2L7K9
names: Similarity
messages: Belongs to the ZC2HC1 family.

89673:FFAR3
gene id: 89673:FFAR3
uniprot id: A0A6J2N8L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:LOC114490469
gene id: 89673:LOC114490469
uniprot id: A0A6J2L1V4
uniprot id: A0A7E6D2V2
names: Similarity
messages: Belongs to the actin family.

89673:HMGB2
gene id: 89673:HMGB2
uniprot id: A0A6J2MA32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

89673:FAR1
gene id: 89673:FAR1
uniprot id: A0A6J2M0H3
uniprot id: A0A7E6E0D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acyl-CoA reductase family.
messages: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
messages: Peroxisome membrane

89673:TOR1AIP1
gene id: 89673:TOR1AIP1
uniprot id: A0A7E6CXF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOR1AIP family.
messages: Membrane

89673:PDXK
gene id: 89673:PDXK
uniprot id: A0A6J2L2L9
names: Similarity
messages: Belongs to the pyridoxine kinase family.

89673:ELAC2
gene id: 89673:ELAC2
uniprot id: A0A6J2NJL2
uniprot id: A0A7E6EBW3
uniprot id: A0A7E6EBZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Z family.
messages: mitochondrion nucleoid

89673:LOC114501916
gene id: 89673:LOC114501916
uniprot id: A0A7E6E6B8
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

89673:PSMC3
gene id: 89673:PSMC3
uniprot id: A0A6J2LYD8
names: Similarity
messages: Belongs to the AAA ATPase family.

89673:PXN
gene id: 89673:PXN
uniprot id: A0A6J2MW91
uniprot id: A0A6J2N0T2
uniprot id: A0A7E6CW77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paxillin family.
messages: cell cortex
messages: cytoskeleton
messages: focal adhesion

89673:SLC26A4
gene id: 89673:SLC26A4
uniprot id: A0A6J2MUX2
uniprot id: A0A7E6CI89
uniprot id: A0A7E6CIM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane
messages: Sodium-independent transporter of chloride and iodide.

89673:PRKCB
gene id: 89673:PRKCB
uniprot id: A0A7E6DE27
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domain.
messages: Cytoplasm
messages: Membrane

89673:LOC114511650
gene id: 89673:LOC114511650
uniprot id: A0A6J2KZF7
uniprot id: A0A6J2N8D7
uniprot id: A0A7E6CLR2
uniprot id: A0A7E6CLV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

89673:TLL1
gene id: 89673:TLL1
uniprot id: A0A6J2MF28
uniprot id: A0A7E6E873
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:KCNJ1
gene id: 89673:KCNJ1
uniprot id: A0A6J2N250
uniprot id: A0A7E6CSK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

89673:NDUFB1
gene id: 89673:NDUFB1
uniprot id: A0A6J2L7B0
uniprot id: A0A6J2L7W9
uniprot id: A0A7E6CQW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

89673:CCNO
gene id: 89673:CCNO
uniprot id: A0A6J2L591
names: Similarity
messages: Belongs to the cyclin family.

89673:TMEM33
gene id: 89673:TMEM33
uniprot id: A0A6J2L794
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

89673:ADHFE1
gene id: 89673:ADHFE1
uniprot id: A0A6J2NCT0
uniprot id: A0A7E6E6P3
uniprot id: A0A7E6E7T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
messages: Mitochondrion

89673:CUTC
gene id: 89673:CUTC
uniprot id: A0A6J2LKL1
names: Similarity
messages: Belongs to the CutC family.

89673:TMEM161B
gene id: 89673:TMEM161B
uniprot id: A0A6J2LZF2
uniprot id: A0A6J2M1I5
uniprot id: A0A7E6DAN4
uniprot id: A0A7E6DAR6
uniprot id: A0A7E6DB19
uniprot id: A0A7E6DD94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM161 family.
messages: Membrane

89673:LIM2
gene id: 89673:LIM2
uniprot id: A0A6J2N1J5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis.

89673:CPOX
gene id: 89673:CPOX
uniprot id: A0A6J2L4A4
names: Similarity
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Homodimer.

89673:LOC114514614
gene id: 89673:LOC114514614
uniprot id: A0A6J2NAW2
names: Similarity
messages: Belongs to the histone H3 family.

89673:VCAM1
gene id: 89673:VCAM1
uniprot id: A0A6J2KU52
uniprot id: A0A6J2KVP9
names: Subcellular Location Annotation
messages: Cell membrane

89673:RELL1
gene id: 89673:RELL1
uniprot id: A0A6J2LE34
names: Similarity
messages: Belongs to the RELT family.

89673:LOC114496815
gene id: 89673:LOC114496815
uniprot id: A0A7E6DPS2
names: Subcellular Location Annotation
messages: Nucleus

89673:AP4M1
gene id: 89673:AP4M1
uniprot id: A0A7E6DBS7
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

89673:HTT
gene id: 89673:HTT
uniprot id: A0A6J2L221
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the huntingtin family.
messages: Cytoplasm
messages: May play a role in microtubule-mediated transport or vesicle function.
messages: Nucleus

89673:TGFA
gene id: 89673:TGFA
uniprot id: A0A7E6DYN4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:NFIL3
gene id: 89673:NFIL3
uniprot id: A0A6J2N601
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts. Represses transcriptional activity of PER1. Represses transcriptional activity of PER2 via the B-site on the promoter. Activates transcription from the interleukin-3 promoter in T-cells. Competes for the same consensus-binding site with PAR DNA-binding factors (DBP, HLF and TEF). Component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock. Protects pro-B cells from programmed cell death.
messages: Belongs to the bZIP family. NFIL3 subfamily.
messages: Homodimer. Binds DNA as a dimer.
messages: Nucleus

89673:NT5DC1
gene id: 89673:NT5DC1
uniprot id: A0A6J2LDC1
uniprot id: A0A7E6DMW3
uniprot id: A0A7E6DND5
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

89673:YIPF2
gene id: 89673:YIPF2
uniprot id: A0A6J2M9X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Late endosome membrane
messages: Membrane
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

89673:LOC114503680
gene id: 89673:LOC114503680
uniprot id: A0A7E6E9C8
names: Subcellular Location Annotation
messages: Membrane

89673:ELMO3
gene id: 89673:ELMO3
uniprot id: A0A6J2KX31
uniprot id: A0A7E6CLZ2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

89673:LUC7L
gene id: 89673:LUC7L
uniprot id: A0A6J2L7V2
uniprot id: A0A6J2LAE7
uniprot id: A0A6J2LAG7
uniprot id: A0A7E6DCG3
uniprot id: A0A7E6DD95
names: Similarity
messages: Belongs to the Luc7 family.

89673:HSCB
gene id: 89673:HSCB
uniprot id: A0A6J2N4B6
uniprot id: A0A7E6CUA9
uniprot id: A0A7E6CUB1
uniprot id: A0A7E6CUU6
uniprot id: A0A7E6CV45
uniprot id: A0A7E6CX40
names: Similarity
messages: Belongs to the HscB family.

89673:ARHGEF12
gene id: 89673:ARHGEF12
uniprot id: A0A7E6DYH1
uniprot id: A0A7E6DYH5
uniprot id: A0A7E6DYK7
uniprot id: A0A7E6DYL2
uniprot id: A0A7E6DZ08
uniprot id: A0A7E6DZF5
uniprot id: A0A7E6DZG1
uniprot id: A0A7E6DZU7
uniprot id: A0A7E6DZV1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane

89673:LOC114490172
gene id: 89673:LOC114490172
uniprot id: A0A6J2KXF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ABCC6
gene id: 89673:ABCC6
uniprot id: A0A6J2L164
uniprot id: A0A7E6DBU7
uniprot id: A0A7E6DC84
uniprot id: A0A7E6DCV6
uniprot id: A0A7E6DDJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

89673:FCF1
gene id: 89673:FCF1
uniprot id: A0A6J2L725
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP23/FCF1 family. FCF1 subfamily.
messages: nucleolus

89673:TCTN2
gene id: 89673:TCTN2
uniprot id: A0A7E6CU08
uniprot id: A0A7E6CU15
uniprot id: A0A7E6CWU2
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

89673:KIF11
gene id: 89673:KIF11
uniprot id: A0A6J2LQI8
uniprot id: A0A7E6DVG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-5/BimC subfamily.
messages: spindle pole

89673:XRCC6
gene id: 89673:XRCC6
uniprot id: A0A6J2NE88
uniprot id: A0A7E6D8L6
uniprot id: A0A7E6D9B4
uniprot id: A0A7E6DBD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ku70 family.
messages: Nucleus

89673:MED14
gene id: 89673:MED14
uniprot id: A0A6J2MJ09
uniprot id: A0A7E6CZ53
uniprot id: A0A7E6D007
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 14 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

89673:MIGA2
gene id: 89673:MIGA2
uniprot id: A0A6J2LTK5
names: Similarity
messages: Belongs to the mitoguardin family.

89673:GPR135
gene id: 89673:GPR135
uniprot id: A0A6J2LCM6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:OPN4
gene id: 89673:OPN4
uniprot id: A0A7E6DTS1
uniprot id: A0A7E6DUE1
uniprot id: A0A7E6DV17
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:LOC114506608
gene id: 89673:LOC114506608
uniprot id: A0A6J2MJ70
uniprot id: A0A7E6CEX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prion family.
messages: Cell membrane
messages: Golgi apparatus
messages: Membrane

89673:NFE2L3
gene id: 89673:NFE2L3
uniprot id: A0A6J2MVP2
uniprot id: A0A7E6CHB4
uniprot id: A0A7E6CHE2
uniprot id: A0A7E6CHE5
uniprot id: A0A7E6CHL2
uniprot id: A0A7E6CHR9
uniprot id: A0A7E6CHS3
uniprot id: A0A7E6CJE9
names: Similarity
messages: Belongs to the bZIP family. CNC subfamily.

89673:LOC114514370
gene id: 89673:LOC114514370
uniprot id: A0A6J2NA36
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

89673:POLG
gene id: 89673:POLG
uniprot id: A0A7E6CPX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-A family.
messages: Involved in the replication of mitochondrial DNA. Associates with mitochondrial DNA.
messages: mitochondrion nucleoid

89673:LOC114512762
gene id: 89673:LOC114512762
uniprot id: A0A6J2NCC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAGP family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane

89673:GCAT
gene id: 89673:GCAT
uniprot id: A0A6J2N8R4
uniprot id: A0A7E6D906
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

89673:MC5R
gene id: 89673:MC5R
uniprot id: A0A6J2MR61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.

89673:DNAH17
gene id: 89673:DNAH17
uniprot id: A0A6J2MCQ2
names: Similarity
messages: Belongs to the dynein heavy chain family.

89673:MGST2
gene id: 89673:MGST2
uniprot id: A0A7E6E9V8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:LOC114511822
gene id: 89673:LOC114511822
uniprot id: A0A6J2N3D2
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Belongs to the intercrine gamma family.

89673:PIP4P2
gene id: 89673:PIP4P2
uniprot id: A0A6J2M4K4
uniprot id: A0A6J2M7C5
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane
messages: phagosome membrane

89673:SLC2A10
gene id: 89673:SLC2A10
uniprot id: A0A7E6CHW0
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

89673:LOC114502314
gene id: 89673:LOC114502314
uniprot id: A0A6J2M618
uniprot id: A0A7E6E947
uniprot id: A0A7E6EAR0
uniprot id: A0A7E6EB57
names: Subcellular Location Annotation
messages: Nucleus

89673:SPNS3
gene id: 89673:SPNS3
uniprot id: A0A6J2NCI9
uniprot id: A0A7E6EBZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

89673:ROPN1L
gene id: 89673:ROPN1L
uniprot id: A0A7E6DB55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ropporin family.
messages: flagellum

89673:TGS1
gene id: 89673:TGS1
uniprot id: A0A6J2NIN1
names: Similarity
messages: Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.

89673:TCAF2
gene id: 89673:TCAF2
uniprot id: A0A6J2MPC4
names: Similarity
messages: Belongs to the TCAF family.

89673:FLT1
gene id: 89673:FLT1
uniprot id: A0A7E6D4W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

89673:NUP62
gene id: 89673:NUP62
uniprot id: A0A6J2N086
names: Similarity
messages: Belongs to the nucleoporin NSP1/NUP62 family.

89673:GOLM1
gene id: 89673:GOLM1
uniprot id: A0A6J2LDX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLM family.
messages: Membrane

89673:WDR44
gene id: 89673:WDR44
uniprot id: A0A6J2MET3
names: Subcellular Location Annotation
messages: trans-Golgi network

89673:LOC114499545
gene id: 89673:LOC114499545
uniprot id: A0A6J2M0M2
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

89673:SUFU
gene id: 89673:SUFU
uniprot id: A0A6J2LQH1
uniprot id: A0A6J2LUL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUFU family.
messages: Cytoplasm
messages: Negative regulator in the hedgehog signaling pathway. Down-regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of GLI3 (GLI3FL). GLI3FL is complexed with SUFU in the cytoplasm and is maintained in a neutral state. Without the Hh signal, the SUFU-GLI3 complex is recruited to cilia, leading to the efficient processing of GLI3FL into GLI3R. When Hh signaling is initiated, SUFU dissociates from GLI3FL and the latter translocates to the nucleus, where it is phosphorylated, destabilized, and converted to a transcriptional activator (GLI3A).
messages: Nucleus

89673:MYCBP2
gene id: 89673:MYCBP2
uniprot id: A0A6J2MPS6
uniprot id: A0A7E6CJR1
uniprot id: A0A7E6CJR7
uniprot id: A0A7E6CJR8
uniprot id: A0A7E6CJS4
uniprot id: A0A7E6CJT4
uniprot id: A0A7E6CJT6
uniprot id: A0A7E6CJU1
uniprot id: A0A7E6CJU7
uniprot id: A0A7E6CJV6
uniprot id: A0A7E6CJW7
uniprot id: A0A7E6CLT3
uniprot id: A0A7E6CLU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RING-Cys relay (RCR) family.
messages: axon

89673:PLSCR3
gene id: 89673:PLSCR3
uniprot id: A0A6J2NEY5
uniprot id: A0A7E6ECE4
uniprot id: A0A7E6EDF6
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

89673:UNCX
gene id: 89673:UNCX
uniprot id: A0A6J2MRY2
names: Subcellular Location Annotation
messages: Nucleus

89673:EIF4A3
gene id: 89673:EIF4A3
uniprot id: A0A6J2MB32
names: Similarity
messages: Belongs to the DEAD box helicase family.

89673:LOC114498935
gene id: 89673:LOC114498935
uniprot id: A0A6J2LXN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:HR
gene id: 89673:HR
uniprot id: A0A6J2MED0
uniprot id: A0A7E6EBV1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM2 histone demethylase family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code.
messages: Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors.
messages: Nucleus
messages: The JmjC domain and the C6-type zinc-finger are required for the demethylation activity.

89673:CBFB
gene id: 89673:CBFB
uniprot id: A0A6J2NDG2
uniprot id: A0A6J2NFG8
uniprot id: A0A6J2NJN7
uniprot id: A0A6J2NJX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF-beta family.
messages: Nucleus

89673:NUTF2
gene id: 89673:NUTF2
uniprot id: A0A6J2KW85
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

89673:PTGDS
gene id: 89673:PTGDS
uniprot id: A0A6J2MUF1
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

89673:TUBGCP3
gene id: 89673:TUBGCP3
uniprot id: A0A6J2MRR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

89673:RFT1
gene id: 89673:RFT1
uniprot id: A0A6J2M955
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFT1 family.
messages: May be involved in N-linked oligosaccharide assembly.
messages: Membrane

89673:EEF2K
gene id: 89673:EEF2K
uniprot id: A0A7E6DE38
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. Alpha-type protein kinase family.
messages: Monomer or homodimer.
messages: Undergoes calcium/calmodulin-dependent intramolecular autophosphorylation, and this results in it becoming partially calcium/calmodulin-independent.

89673:VPS45
gene id: 89673:VPS45
uniprot id: A0A6J2KTG5
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

89673:TRPV3
gene id: 89673:TRPV3
uniprot id: A0A6J2NJN0
names: Subcellular Location Annotation
messages: Membrane

89673:DPYS
gene id: 89673:DPYS
uniprot id: A0A6J2NIE0
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

89673:SLC14A1
gene id: 89673:SLC14A1
uniprot id: A0A7E6CFN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

89673:RORA
gene id: 89673:RORA
uniprot id: A0A6J2L8Z2
uniprot id: A0A6J2L9E6
uniprot id: A0A6J2LEL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

89673:INPP5B
gene id: 89673:INPP5B
uniprot id: A0A6J2LL64
uniprot id: A0A7E6DR45
uniprot id: A0A7E6DR82
uniprot id: A0A7E6DRZ7
uniprot id: A0A7E6DSD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: phagosome membrane

89673:LIPG
gene id: 89673:LIPG
uniprot id: A0A6J2MJK3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:SFR1
gene id: 89673:SFR1
uniprot id: A0A6J2LQ35
uniprot id: A0A7E6DVA5
uniprot id: A0A7E6DVF0
uniprot id: A0A7E6DVX2
uniprot id: A0A7E6DW91
uniprot id: A0A7E6DWP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFR1/MEI5 family.
messages: Nucleus

89673:ENY2
gene id: 89673:ENY2
uniprot id: A0A6J2NCC6
uniprot id: A0A6J2NH81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ENY2 family.
messages: Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2), composed of at least ENY2, GANP, PCID2, DSS1, and either centrin CETN2 or CETN3. TREX-2 contains 2 ENY2 chains. The TREX-2 complex interacts with the nucleoporin NUP153. Component of some SAGA transcription coactivator-HAT complexes, at least composed of ATXN7, ATXN7L3, ENY2, GCN5L2, SUPT3H, TAF10, TRRAP and USP22. Within the SAGA complex, ENY2, ATXN7, ATXN7L3, and USP22 form an additional subcomplex of SAGA called the DUB module (deubiquitination module). Interacts directly with ATXN7L3, GANP and with the RNA polymerase II. Interacts strongly with ATXN7L3 and ATXN7L3B.
messages: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
messages: nucleoplasm

89673:LOC114501998
gene id: 89673:LOC114501998
uniprot id: A0A7E6E7D5
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

89673:RIPK2
gene id: 89673:RIPK2
uniprot id: A0A7E6E6T9
uniprot id: A0A7E6E7G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
messages: Cytoplasm
messages: Found in a signaling complex consisting of at least ARHGEF2, NOD2 and RIPK2.
messages: Serine/threonine/tyrosine-protein kinase that plays an essential role in modulation of innate and adaptive immune responses. Acts as a key effector of NOD1 and NOD2 signaling pathways: upon activation by bacterial peptidoglycans, NOD1 and NOD2 oligomerize and recruit RIPK2 via CARD-CARD domains, leading to the formation of RIPK2 filaments.

89673:SEMA3G
gene id: 89673:SEMA3G
uniprot id: A0A6J2M947
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:UTP23
gene id: 89673:UTP23
uniprot id: A0A6J2NCX1
names: Subcellular Location Annotation
messages: nucleolus

89673:LOC114500479
gene id: 89673:LOC114500479
uniprot id: A0A6J2M132
names: Subcellular Location Annotation
messages: Membrane

89673:PRDM10
gene id: 89673:PRDM10
uniprot id: A0A6J2MXN3
uniprot id: A0A7E6CU20
uniprot id: A0A7E6CWU7
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

89673:HERC4
gene id: 89673:HERC4
uniprot id: A0A7E6DU90
uniprot id: A0A7E6DUU5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:FER
gene id: 89673:FER
uniprot id: A0A7E6DB11
uniprot id: A0A7E6DBG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.
messages: Cell membrane
messages: Membrane
messages: cytoskeleton

89673:PON1
gene id: 89673:PON1
uniprot id: A0A6J2MQA1
uniprot id: A0A7E6CHS1
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the paraoxonase family.
messages: Binds 2 calcium ions per subunit.
messages: Glycosylated.

89673:ADRA2C
gene id: 89673:ADRA2C
uniprot id: A0A6J2KW54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:LOC114504959
gene id: 89673:LOC114504959
uniprot id: A0A7E6CZV9
names: Similarity
messages: Belongs to the uridine kinase family.

89673:BCLAF3
gene id: 89673:BCLAF3
uniprot id: A0A7E6CZK2
uniprot id: A0A7E6D037
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

89673:AUP1
gene id: 89673:AUP1
uniprot id: A0A6J2M5W2
uniprot id: A0A7E6DY33
uniprot id: A0A7E6DYH4
uniprot id: A0A7E6DYZ4
uniprot id: A0A7E6DZC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AUP1 family.
messages: Membrane

89673:CDC42BPG
gene id: 89673:CDC42BPG
uniprot id: A0A6J2LYN9
uniprot id: A0A7E6E2K4
uniprot id: A0A7E6E2R9
uniprot id: A0A7E6E3H1
uniprot id: A0A7E6E3H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
messages: Cytoplasm

89673:CHDH
gene id: 89673:CHDH
uniprot id: A0A6J2M981
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

89673:BAG6
gene id: 89673:BAG6
uniprot id: A0A6J2LF37
uniprot id: A0A6J2LF42
uniprot id: A0A6J2LG29
uniprot id: A0A6J2LHB2
uniprot id: A0A6J2LHC1
uniprot id: A0A6J2LJU5
uniprot id: A0A6J2LJW0
uniprot id: A0A6J2LKP3
uniprot id: A0A6J2LKQ1
uniprot id: A0A7E6DKS5
uniprot id: A0A7E6DL36
uniprot id: A0A7E6DL65
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Released extracellularly via exosomes, it is a ligand of the natural killer/NK cells receptor NCR3 and stimulates NK cells cytotoxicity. It may thereby trigger NK cells cytotoxicity against neighboring tumor cells and immature myeloid dendritic cells (DC).
messages: cytosol
messages: extracellular exosome

89673:CLUH
gene id: 89673:CLUH
uniprot id: A0A6J2M627
uniprot id: A0A6J2M6I5
uniprot id: A0A7E6EDX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLU family.
messages: Cytoplasm
messages: Cytoplasmic granule
messages: mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear-encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis.

89673:RET
gene id: 89673:RET
uniprot id: A0A6J2LSV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane
messages: Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.

89673:CAD
gene id: 89673:CAD
uniprot id: A0A6J2LSQ5
uniprot id: A0A6J2LTJ8
uniprot id: A0A7E6DX93
uniprot id: A0A7E6DY46
names: Similarity
messages: In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily.

89673:CNTN1
gene id: 89673:CNTN1
uniprot id: A0A6J2N5E7
uniprot id: A0A6J2N7I4
names: Similarity
messages: Belongs to the immunoglobulin superfamily. Contactin family.

89673:ITFG1
gene id: 89673:ITFG1
uniprot id: A0A6J2KSM5
names: Similarity
messages: Belongs to the TIP family.

89673:GAB2
gene id: 89673:GAB2
uniprot id: A0A6J2M2C3
names: Similarity
messages: Belongs to the GAB family.

89673:NKX2-3
gene id: 89673:NKX2-3
uniprot id: A0A6J2LJQ5
names: Subcellular Location Annotation
messages: Nucleus

89673:TGM6
gene id: 89673:TGM6
uniprot id: A0A6J2MJ56
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

89673:TAZ
gene id: 89673:TAZ
uniprot id: A0A6J2MH36
uniprot id: A0A6J2MHG6
uniprot id: A0A6J2MLD6
uniprot id: A0A7E6D0L1
uniprot id: A0A7E6D1A1
uniprot id: A0A7E6D1A5
uniprot id: A0A7E6D368
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acyltransferase which is required to remodel newly synthesized phospholipid cardiolipin, a key component of the mitochondrial inner membrane. Required for the initiation of mitophagy. Required to ensure progression of spermatocytes through meiosis.
messages: Associates with multiple protein complexes.
messages: Belongs to the taffazin family.
messages: Mitochondrion inner membrane
messages: Mitochondrion outer membrane

89673:CLUAP1
gene id: 89673:CLUAP1
uniprot id: A0A6J2LKS9
uniprot id: A0A6J2LKT6
uniprot id: A0A7E6D978
uniprot id: A0A7E6D9B1
uniprot id: A0A7E6D9H2
uniprot id: A0A7E6DA61
uniprot id: A0A7E6DC85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLUAP1 family.
messages: cilium

89673:LOC114504712
gene id: 89673:LOC114504712
uniprot id: A0A7E6D458
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. As part of the U7 snRNP it is involved in histone 3'-end processing.
messages: cytosol

89673:GPR3
gene id: 89673:GPR3
uniprot id: A0A6J2LRX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:LOC114490189
gene id: 89673:LOC114490189
uniprot id: A0A6J2KXH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SLC25A31
gene id: 89673:SLC25A31
uniprot id: A0A6J2MDI6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

89673:LMLN2
gene id: 89673:LMLN2
uniprot id: A0A7E6CVM8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M8 family.
messages: Binds 1 zinc ion per subunit.

89673:GNG2
gene id: 89673:GNG2
uniprot id: A0A7E6CGC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

89673:EPC2
gene id: 89673:EPC2
uniprot id: A0A6J2L938
uniprot id: A0A6J2L9K3
uniprot id: A0A7E6DJZ9
uniprot id: A0A7E6DK99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enhancer of polycomb family.
messages: Nucleus

89673:PIK3C3
gene id: 89673:PIK3C3
uniprot id: A0A6J2MLC3
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

89673:SNX8
gene id: 89673:SNX8
uniprot id: A0A6J2MUM8
uniprot id: A0A6J2MWA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

89673:RAB19
gene id: 89673:RAB19
uniprot id: A0A6J2MV72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane

89673:MYBBP1A
gene id: 89673:MYBBP1A
uniprot id: A0A6J2NDM6
uniprot id: A0A7E6ECL9
uniprot id: A0A7E6EDT1
names: Similarity
messages: Belongs to the MYBBP1A family.

89673:PSD2
gene id: 89673:PSD2
uniprot id: A0A6J2MX49
uniprot id: A0A7E6CSI9
names: Subcellular Location Annotation
messages: Membrane
messages: ruffle membrane

89673:PLD5
gene id: 89673:PLD5
uniprot id: A0A6J2NA19
uniprot id: A0A7E6CYG6
uniprot id: A0A7E6CYL2
uniprot id: A0A7E6D136
names: Similarity
messages: Belongs to the phospholipase D family.

89673:CISD2
gene id: 89673:CISD2
uniprot id: A0A6J2L6H2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CISD protein family. CISD2 subfamily.
messages: Binds 1 [2Fe-2S] cluster.
messages: Endoplasmic reticulum membrane
messages: Homodimer.
messages: Mitochondrion outer membrane
messages: Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy.

89673:B4GALT6
gene id: 89673:B4GALT6
uniprot id: A0A6J2MSF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

89673:MGAT5
gene id: 89673:MGAT5
uniprot id: A0A6J2L9J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 18 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Secreted

89673:NHEJ1
gene id: 89673:NHEJ1
uniprot id: A0A6J2LJ21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XRCC4-XLF family. XLF subfamily.
messages: Nucleus

89673:LOC114498973
gene id: 89673:LOC114498973
uniprot id: A0A7E6E3K3
names: Similarity
messages: Belongs to the nucleobindin family.

89673:NADSYN1
gene id: 89673:NADSYN1
uniprot id: A0A6J2L261
uniprot id: A0A7E6E370
names: Similarity
names: Subunit
messages: Homohexamer.
messages: In the C-terminal section; belongs to the NAD synthetase family.

89673:LOC114498540
gene id: 89673:LOC114498540
uniprot id: A0A6J2LRC7
names: Subcellular Location Annotation
messages: Membrane

89673:SPOUT1
gene id: 89673:SPOUT1
uniprot id: A0A6J2MPG1
uniprot id: A0A7E6DGU8
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily.

89673:RAB3D
gene id: 89673:RAB3D
uniprot id: A0A6J2MDH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

89673:PACS1
gene id: 89673:PACS1
uniprot id: A0A6J2LZ30
uniprot id: A0A7E6E2T8
names: Similarity
messages: Belongs to the PACS family.

89673:PBX3
gene id: 89673:PBX3
uniprot id: A0A6J2L7P5
uniprot id: A0A6J2LBW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

89673:LOC114504252
gene id: 89673:LOC114504252
uniprot id: A0A6J2MEN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:MDGA2
gene id: 89673:MDGA2
uniprot id: A0A7E6DZP8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:LOC114498469
gene id: 89673:LOC114498469
uniprot id: A0A6J2LS98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Secreted

89673:PLXNC1
gene id: 89673:PLXNC1
uniprot id: A0A6J2ND52
names: Caution
names: Similarity
messages: Belongs to the plexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:FGF22
gene id: 89673:FGF22
uniprot id: A0A6J2MCQ4
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

89673:LOC114499099
gene id: 89673:LOC114499099
uniprot id: A0A6J2LSX3
uniprot id: A0A7E6DX65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:MFN1
gene id: 89673:MFN1
uniprot id: A0A6J2KU48
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

89673:GLIS3
gene id: 89673:GLIS3
uniprot id: A0A6J2MX63
uniprot id: A0A7E6DEW9
uniprot id: A0A7E6DEZ6
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

89673:ACTR2
gene id: 89673:ACTR2
uniprot id: A0A6J2LTQ1
uniprot id: A0A6J2LUV4
names: Similarity
messages: Belongs to the actin family.

89673:SIN3A
gene id: 89673:SIN3A
uniprot id: A0A6J2LA45
names: Subcellular Location Annotation
messages: Nucleus

89673:SLC30A10
gene id: 89673:SLC30A10
uniprot id: A0A6J2NB06
uniprot id: A0A7E6CYZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

89673:WDR3
gene id: 89673:WDR3
uniprot id: A0A6J2KXU9
names: Subcellular Location Annotation
messages: nucleolus

89673:LOC114488384
gene id: 89673:LOC114488384
uniprot id: A0A7E6CM72
names: Caution
names: Function
names: Similarity
messages: As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.
messages: Belongs to the peptidase S1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:SFRP5
gene id: 89673:SFRP5
uniprot id: A0A6J2LS76
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114500870
gene id: 89673:LOC114500870
uniprot id: A0A6J2M0A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114490770
gene id: 89673:LOC114490770
uniprot id: A0A7E6D2R0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:SOGA3
gene id: 89673:SOGA3
uniprot id: A0A6J2LD35
uniprot id: A0A7E6DN33
uniprot id: A0A7E6DP19
names: Similarity
messages: Belongs to the SOGA family.

89673:LOC114506163
gene id: 89673:LOC114506163
uniprot id: A0A7E6CGL9
names: Subcellular Location Annotation
messages: Nucleus

89673:PTTG1
gene id: 89673:PTTG1
uniprot id: A0A6J2MVD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the securin family.
messages: Cytoplasm
messages: Nucleus

89673:LOC114505553
gene id: 89673:LOC114505553
uniprot id: A0A7E6D1J5
names: Similarity
messages: Belongs to the pro/parathymosin family.

89673:PELI2
gene id: 89673:PELI2
uniprot id: A0A6J2L735
names: Function
names: Similarity
messages: Belongs to the pellino family.
messages: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.

89673:LOC114500438
gene id: 89673:LOC114500438
uniprot id: A0A6J2LYW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TAGLN
gene id: 89673:TAGLN
uniprot id: A0A6J2M0Q0
names: Similarity
messages: Belongs to the calponin family.

89673:VAMP5
gene id: 89673:VAMP5
uniprot id: A0A6J2LYE4
uniprot id: A0A7E6DY65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

89673:ALDH3A2
gene id: 89673:ALDH3A2
uniprot id: A0A6J2NE75
uniprot id: A0A7E6EAZ5
uniprot id: A0A7E6ECJ5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

89673:CCDC22
gene id: 89673:CCDC22
uniprot id: A0A6J2MG61
uniprot id: A0A7E6D0R7
names: Similarity
messages: Belongs to the CCDC22 family.

89673:FAN1
gene id: 89673:FAN1
uniprot id: A0A6J2KSC9
uniprot id: A0A7E6CPP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAN1 family.
messages: Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
messages: Nucleus

89673:RNF40
gene id: 89673:RNF40
uniprot id: A0A6J2L659
uniprot id: A0A6J2L8A9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BRE1 family.
messages: Component of the RNF20/40 complex (also known as BRE1 complex) probably composed of 2 copies of RNF20/BRE1A and 2 copies of RNF40/BRE1B. Interacts with UBE2E1/UBCH6.
messages: Nucleus

89673:FBLN1
gene id: 89673:FBLN1
uniprot id: A0A6J2N9N6
uniprot id: A0A6J2NEA8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fibulin family.
messages: Homomultimerizes and interacts with various extracellular matrix components.
messages: Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

89673:DNAH11
gene id: 89673:DNAH11
uniprot id: A0A7E6CHG0
uniprot id: A0A7E6CHQ9
uniprot id: A0A7E6CHW3
names: Similarity
messages: Belongs to the dynein heavy chain family.

89673:SATB2
gene id: 89673:SATB2
uniprot id: A0A6J2LCK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

89673:MAPKAPK2
gene id: 89673:MAPKAPK2
uniprot id: A0A6J2N8W2
uniprot id: A0A7E6CZ87
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:ALKBH8
gene id: 89673:ALKBH8
uniprot id: A0A6J2M4E9
uniprot id: A0A7E6DZ67
uniprot id: A0A7E6DZN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkB family.
messages: Cytoplasm

89673:PCSK2
gene id: 89673:PCSK2
uniprot id: A0A6J2MRN9
names: Similarity
messages: Belongs to the peptidase S8 family.

89673:SOGA1
gene id: 89673:SOGA1
uniprot id: A0A6J2MPB9
uniprot id: A0A7E6CFD8
uniprot id: A0A7E6CG00
names: Similarity
messages: Belongs to the SOGA family.

89673:UBL4A
gene id: 89673:UBL4A
uniprot id: A0A6J2MHQ9
uniprot id: A0A7E6D0R9
names: Subcellular Location Annotation
messages: cytosol

89673:UCP3
gene id: 89673:UCP3
uniprot id: A0A6J2LZH4
uniprot id: A0A7E6DZU0
uniprot id: A0A7E6E0B1
uniprot id: A0A7E6E100
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

89673:TSFM
gene id: 89673:TSFM
uniprot id: A0A6J2N931
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Mitochondrion

89673:WEE1
gene id: 89673:WEE1
uniprot id: A0A6J2LZB7
uniprot id: A0A7E6E0F3
uniprot id: A0A7E6E1F5
uniprot id: A0A7E6E1H7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
messages: Binds 2 magnesium ions per subunit.
messages: Nucleus

89673:SLC13A4
gene id: 89673:SLC13A4
uniprot id: A0A6J2MUQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

89673:SLC25A35
gene id: 89673:SLC25A35
uniprot id: A0A6J2NEC8
uniprot id: A0A6J2NJB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

89673:ARV1
gene id: 89673:ARV1
uniprot id: A0A7E6CYF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARV1 family.
messages: Endoplasmic reticulum membrane
messages: Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.
messages: Membrane

89673:GMFG
gene id: 89673:GMFG
uniprot id: A0A7E6CMH5
uniprot id: A0A7E6CML5
names: Similarity
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.

89673:LOC114488724
gene id: 89673:LOC114488724
uniprot id: A0A6J2KUE0
uniprot id: A0A6J2KY92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Golgi pH regulator (TC 1.A.38) family.
messages: Membrane

89673:WT1
gene id: 89673:WT1
uniprot id: A0A7E6E0Q2
uniprot id: A0A7E6E140
uniprot id: A0A7E6E1A9
uniprot id: A0A7E6E1Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Cytoplasm
messages: Nucleus speckle

89673:MMP7
gene id: 89673:MMP7
uniprot id: A0A6J2LXM5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

89673:LIG3
gene id: 89673:LIG3
uniprot id: A0A6J2MDJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

89673:MAST1
gene id: 89673:MAST1
uniprot id: A0A6J2M7V6
uniprot id: A0A6J2MBA4
uniprot id: A0A7E6E9H7
uniprot id: A0A7E6EAB6
uniprot id: A0A7E6EAJ1
uniprot id: A0A7E6EB63
uniprot id: A0A7E6EBJ0
uniprot id: A0A7E6EBK0
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

89673:LOC114512182
gene id: 89673:LOC114512182
uniprot id: A0A6J2N4U9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114490331
gene id: 89673:LOC114490331
uniprot id: A0A6J2L1E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:IFT20
gene id: 89673:IFT20
uniprot id: A0A6J2M6Q9
uniprot id: A0A6J2M8M7
names: Subcellular Location Annotation
messages: centriole
messages: cilium
messages: cis-Golgi network

89673:CDH1
gene id: 89673:CDH1
uniprot id: A0A6J2KQM2
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

89673:LOC114507789
gene id: 89673:LOC114507789
uniprot id: A0A6J2MQ18
uniprot id: A0A7E6CIS6
uniprot id: A0A7E6CJ51
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:LOC114515177
gene id: 89673:LOC114515177
uniprot id: A0A6J2NEU5
uniprot id: A0A7E6ECQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:GPRC5A
gene id: 89673:GPRC5A
uniprot id: A0A7E6D7I6
uniprot id: A0A7E6DAD2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:LOC114509653
gene id: 89673:LOC114509653
uniprot id: A0A6J2N0X0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Adapter involved in the TLR2 and TLR4 signaling pathways in the innate immune response.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer.
messages: Membrane

89673:GPR182
gene id: 89673:GPR182
uniprot id: A0A6J2NAW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:LOC114510724
gene id: 89673:LOC114510724
uniprot id: A0A6J2N503
names: Similarity
messages: Belongs to the MHC class I family.

89673:LOC114505360
gene id: 89673:LOC114505360
uniprot id: A0A6J2MHW5
uniprot id: A0A7E6CZB7
names: Subcellular Location Annotation
messages: Nucleus

89673:C5
gene id: 89673:C5
uniprot id: A0A7E6DG67
uniprot id: A0A7E6DG83
uniprot id: A0A7E6DG84
uniprot id: A0A7E6DG90
uniprot id: A0A7E6DG91
uniprot id: A0A7E6DGD3
uniprot id: A0A7E6DGD8
names: Subcellular Location Annotation
messages: Secreted

89673:LOC114490328
gene id: 89673:LOC114490328
uniprot id: A0A6J2L387
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114493117
gene id: 89673:LOC114493117
uniprot id: A0A6J2LDC9
names: Subcellular Location Annotation
messages: Nucleus

89673:SAG
gene id: 89673:SAG
uniprot id: A0A7E6DHS4
uniprot id: A0A7E6DHW3
uniprot id: A0A7E6DHZ0
names: Similarity
messages: Belongs to the arrestin family.

89673:TET1
gene id: 89673:TET1
uniprot id: A0A6J2LMB8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TET family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Chromosome
messages: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development.
messages: The zinc ions have a structural role.

89673:CKAP2L
gene id: 89673:CKAP2L
uniprot id: A0A6J2LUK8
names: Similarity
messages: Belongs to the CKAP2 family.

89673:TMC4
gene id: 89673:TMC4
uniprot id: A0A6J2N1K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

89673:DHFR
gene id: 89673:DHFR
uniprot id: A0A6J2LR40
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

89673:LOC118500483
gene id: 89673:LOC118500483
uniprot id: A0A7E6DP76
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

89673:LOC114499057
gene id: 89673:LOC114499057
uniprot id: A0A6J2LUV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:DOK3
gene id: 89673:DOK3
uniprot id: A0A6J2N0Y3
names: Similarity
messages: Belongs to the DOK family. Type A subfamily.

89673:TAF9
gene id: 89673:TAF9
uniprot id: A0A6J2L1K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus

89673:N4BP3
gene id: 89673:N4BP3
uniprot id: A0A6J2N0S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the N4BP3 family.
messages: Vesicle
messages: dendrite

89673:DPAGT1
gene id: 89673:DPAGT1
uniprot id: A0A6J2LVQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family.
messages: Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:MAP3K14
gene id: 89673:MAP3K14
uniprot id: A0A6J2MC36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Cytoplasm
messages: Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity.

89673:BLK
gene id: 89673:BLK
uniprot id: A0A6J2M7K7
uniprot id: A0A7E6EA10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

89673:SERF1A
gene id: 89673:SERF1A
uniprot id: A0A7E6DAF0
uniprot id: A0A7E6DAP0
uniprot id: A0A7E6DBG9
names: Similarity
messages: Belongs to the SERF family.

89673:PNPO
gene id: 89673:PNPO
uniprot id: A0A6J2MD48
uniprot id: A0A7E6EFA9
names: Function
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).

89673:LOC114494096
gene id: 89673:LOC114494096
uniprot id: A0A6J2LBC3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:LOC114503096
gene id: 89673:LOC114503096
uniprot id: A0A6J2M8I5
uniprot id: A0A6J2MAK7
uniprot id: A0A6J2MD91
uniprot id: A0A6J2MDV2
uniprot id: A0A7E6EDU9
uniprot id: A0A7E6EE02
uniprot id: A0A7E6EF15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

89673:RDH16
gene id: 89673:RDH16
uniprot id: A0A6J2NBP0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

89673:MUC6
gene id: 89673:MUC6
uniprot id: A0A7E6E4K8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:AGBL2
gene id: 89673:AGBL2
uniprot id: A0A6J2LWI0
uniprot id: A0A7E6E171
uniprot id: A0A7E6E177
uniprot id: A0A7E6E2N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

89673:TOP2A
gene id: 89673:TOP2A
uniprot id: A0A6J2M719
uniprot id: A0A6J2M9Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Homodimer.
messages: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand.
messages: nucleolus
messages: nucleoplasm

89673:PODXL2
gene id: 89673:PODXL2
uniprot id: A0A6J2MLL8
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114511839
gene id: 89673:LOC114511839
uniprot id: A0A6J2N3J8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:RPAIN
gene id: 89673:RPAIN
uniprot id: A0A6J2NFC3
uniprot id: A0A7E6ECP7
uniprot id: A0A7E6EDG5
names: Subcellular Location Annotation
messages: Nucleus

89673:EIF4E1B
gene id: 89673:EIF4E1B
uniprot id: A0A6J2N490
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

89673:LOC114499966
gene id: 89673:LOC114499966
uniprot id: A0A6J2LX70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:RRP7A
gene id: 89673:RRP7A
uniprot id: A0A7E6D9D1
names: Similarity
messages: Belongs to the RRP7 family.

89673:KCNH6
gene id: 89673:KCNH6
uniprot id: A0A6J2MER7
uniprot id: A0A7E6ECW5
names: Subcellular Location Annotation
messages: Membrane

89673:KYNU
gene id: 89673:KYNU
uniprot id: A0A6J2LDP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:CDNF
gene id: 89673:CDNF
uniprot id: A0A6J2L2U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARMET family.
messages: Secreted

89673:CACNG5
gene id: 89673:CACNG5
uniprot id: A0A6J2MBN5
names: Similarity
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.

89673:ASB8
gene id: 89673:ASB8
uniprot id: A0A6J2N4X9
names: Function
messages: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

89673:ATP5MG
gene id: 89673:ATP5MG
uniprot id: A0A6J2M1H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase g subunit family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion

89673:SF3A2
gene id: 89673:SF3A2
uniprot id: A0A6J2MEU8
names: Similarity
messages: Belongs to the SF3A2 family.

89673:MEGF10
gene id: 89673:MEGF10
uniprot id: A0A6J2N7C0
uniprot id: A0A7E6DBN2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:ITPRIPL2
gene id: 89673:ITPRIPL2
uniprot id: A0A7E6DC71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Membrane

89673:LOC114513903
gene id: 89673:LOC114513903
uniprot id: A0A7E6D0X3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:TAS2R38
gene id: 89673:TAS2R38
uniprot id: A0A6J2MLD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

89673:TSPAN14
gene id: 89673:TSPAN14
uniprot id: A0A6J2LLX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

89673:CS
gene id: 89673:CS
uniprot id: A0A6J2NBS6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the citrate synthase family.
messages: Homodimer.
messages: Mitochondrion matrix

89673:LOC114493336
gene id: 89673:LOC114493336
uniprot id: A0A6J2LA41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFI6/IFI27 family.
messages: Membrane

89673:HNRNPA3
gene id: 89673:HNRNPA3
uniprot id: A0A7E6DJH4
names: Subcellular Location Annotation
messages: Nucleus

89673:MEP1B
gene id: 89673:MEP1B
uniprot id: A0A6J2MMM0
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:MS4A13
gene id: 89673:MS4A13
uniprot id: A0A6J2LZY3
uniprot id: A0A7E6E229
uniprot id: A0A7E6E2X6
names: Similarity
messages: Belongs to the MS4A family.

89673:TIMELESS
gene id: 89673:TIMELESS
uniprot id: A0A7E6D6P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the timeless family.
messages: Nucleus

89673:LOC114495196
gene id: 89673:LOC114495196
uniprot id: A0A7E6DHM2
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

89673:RAB3C
gene id: 89673:RAB3C
uniprot id: A0A6J2MTZ4
uniprot id: A0A6J2MVK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

89673:JAK2
gene id: 89673:JAK2
uniprot id: A0A6J2LMK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system
messages: Nucleus

89673:LOC114506203
gene id: 89673:LOC114506203
uniprot id: A0A6J2MHC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PET117 family.
messages: Mitochondrion

89673:CAB39
gene id: 89673:CAB39
uniprot id: A0A6J2LH79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

89673:ARF4
gene id: 89673:ARF4
uniprot id: A0A6J2M3Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

89673:TSSK4
gene id: 89673:TSSK4
uniprot id: A0A6J2L9S6
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:FOXN1
gene id: 89673:FOXN1
uniprot id: A0A6J2MB80
uniprot id: A0A7E6EDX7
names: Subcellular Location Annotation
messages: Nucleus

89673:NAA35
gene id: 89673:NAA35
uniprot id: A0A6J2L865
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues. Involved in regulation of apoptosis and proliferation of smooth muscle cells.
messages: Belongs to the MAK10 family.
messages: Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.
messages: Cytoplasm

89673:SIGIRR
gene id: 89673:SIGIRR
uniprot id: A0A6J2LYM0
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

89673:NMU
gene id: 89673:NMU
uniprot id: A0A7E6DBX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NmU family.
messages: Secreted

89673:MED1
gene id: 89673:MED1
uniprot id: A0A6J2M9V9
uniprot id: A0A6J2MBW6
uniprot id: A0A7E6EFY5
uniprot id: A0A7E6EG81
uniprot id: A0A7E6EGZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 1 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

89673:ALDH1B1
gene id: 89673:ALDH1B1
uniprot id: A0A6J2LYH6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

89673:SH3RF2
gene id: 89673:SH3RF2
uniprot id: A0A6J2N230
uniprot id: A0A7E6CU89
names: Similarity
messages: Belongs to the SH3RF family.

89673:CRKL
gene id: 89673:CRKL
uniprot id: A0A6J2MUD0
names: Similarity
messages: Belongs to the CRK family.

89673:THOC2
gene id: 89673:THOC2
uniprot id: A0A6J2ME48
uniprot id: A0A6J2MK49
uniprot id: A0A7E6CZD8
uniprot id: A0A7E6CZE5
uniprot id: A0A7E6CZF3
uniprot id: A0A7E6CZR5
uniprot id: A0A7E6D207
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the THOC2 family.
messages: Component of the THO complex, which is composed of THOC1, THOC2, THOC3, THOC5, THOC6 and THOC7; together with at least ALYREF/THOC4, DDX39B, SARNP/CIP29 and CHTOP, THO forms the transcription/export (TREX) complex which seems to have a dynamic structure involving ATP-dependent remodeling. Interacts with THOC1, POLDIP3 and ZC3H11A.
messages: Nucleus

89673:GOSR1
gene id: 89673:GOSR1
uniprot id: A0A6J2MDI4
uniprot id: A0A6J2MHA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GOSR1 family.
messages: Component of several multiprotein Golgi SNARE complexes.
messages: Golgi apparatus membrane
messages: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.
messages: Membrane

89673:FLOT1
gene id: 89673:FLOT1
uniprot id: A0A6J2LH82
uniprot id: A0A7E6DKL6
uniprot id: A0A7E6DLB5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Cell membrane
messages: Endosome
messages: Heterooligomeric complex of flotillin-1 and flotillin-2 and caveolin-1 and caveolin-2. Interacts with ECPAS.
messages: Membrane
messages: caveola

89673:CCR3
gene id: 89673:CCR3
uniprot id: A0A7E6E5S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

89673:ACMSD
gene id: 89673:ACMSD
uniprot id: A0A6J2LFT0
uniprot id: A0A7E6DKC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. ACMSD family.
messages: Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway.
messages: Monomer.

89673:ARHGAP33
gene id: 89673:ARHGAP33
uniprot id: A0A6J2MYX3
names: Similarity
messages: Belongs to the PX domain-containing GAP family.

89673:PPOX
gene id: 89673:PPOX
uniprot id: A0A6J2KUU9
uniprot id: A0A6J2KVC3
uniprot id: A0A7E6CXB9
uniprot id: A0A7E6CZ56
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily.
messages: Binds 1 FAD per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
messages: Mitochondrion inner membrane

89673:TYSND1
gene id: 89673:TYSND1
uniprot id: A0A6J2LLL3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1B family.
messages: Peroxisomal protease that mediates both the removal of the leader peptide from proteins containing a PTS2 target sequence and processes several PTS1-containing proteins. Catalyzes the processing of PTS1-proteins involved in the peroxisomal beta-oxidation of fatty acids.
messages: Peroxisome
messages: The full-lengh TYSND1 is the active the proteolytic processing of PTS1- and PTS2-proteins and in self-cleavage, and intermolecular self-cleavage of TYSND1 down-regulates its protease activity.

89673:SULT2A1
gene id: 89673:SULT2A1
uniprot id: A0A6J2N7Q4
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

89673:GANC
gene id: 89673:GANC
uniprot id: A0A6J2L7G6
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

89673:LOC114498892
gene id: 89673:LOC114498892
uniprot id: A0A6J2LXJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ATP12A
gene id: 89673:ATP12A
uniprot id: A0A7E6D4Y8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:PRKN
gene id: 89673:PRKN
uniprot id: A0A7E6DNV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RBR family. Parkin subfamily.
messages: Forms an E3 ubiquitin ligase complex.
messages: Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.
messages: Mitochondrion
messages: cytosol

89673:LOC114505594
gene id: 89673:LOC114505594
uniprot id: A0A7E6D0F6
names: Similarity
messages: Belongs to the SPT20 family.

89673:GUF1
gene id: 89673:GUF1
uniprot id: A0A6J2LCD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. LepA subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Mitochondrion inner membrane
messages: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.

89673:AP2A1
gene id: 89673:AP2A1
uniprot id: A0A7E6CNE2
uniprot id: A0A7E6CNL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit AP2A1 or AP2A2 and beta-type subunit AP2B1), a medium adaptin (mu-type subunit AP2M1) and a small adaptin (sigma-type subunit AP2S1).
messages: Belongs to the adaptor complexes large subunit family.
messages: Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules. AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway. The AP-2 alpha subunit binds polyphosphoinositide-containing lipids, positioning AP-2 on the membrane. The AP-2 alpha subunit acts via its C-terminal appendage domain as a scaffolding platform for endocytic accessory proteins. The AP-2 alpha and AP-2 sigma subunits are thought to contribute to the recognition of the [ED]-X-X-X-L-[LI] motif.
messages: coated pit

89673:FOXE3
gene id: 89673:FOXE3
uniprot id: A0A7E6DWH7
names: Subcellular Location Annotation
messages: Nucleus

89673:CRYBA4
gene id: 89673:CRYBA4
uniprot id: A0A6J2N0P5
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

89673:LOC114500219
gene id: 89673:LOC114500219
uniprot id: A0A6J2M361
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ABLIM1
gene id: 89673:ABLIM1
uniprot id: A0A6J2LJ78
uniprot id: A0A6J2LKE6
uniprot id: A0A6J2LLH2
uniprot id: A0A6J2LP56
uniprot id: A0A6J2LPS3
uniprot id: A0A7E6DVH6
uniprot id: A0A7E6DVI5
uniprot id: A0A7E6DVI9
uniprot id: A0A7E6DVN8
uniprot id: A0A7E6DVP1
uniprot id: A0A7E6DVQ0
uniprot id: A0A7E6DVR0
uniprot id: A0A7E6DW41
uniprot id: A0A7E6DW47
uniprot id: A0A7E6DW49
uniprot id: A0A7E6DW55
uniprot id: A0A7E6DWG4
uniprot id: A0A7E6DWG9
uniprot id: A0A7E6DWH2
uniprot id: A0A7E6DWH8
uniprot id: A0A7E6DWX3
uniprot id: A0A7E6DWX8
uniprot id: A0A7E6DWY4
uniprot id: A0A7E6DWY9
names: Subcellular Location Annotation
messages: Cytoplasm

89673:G6PC3
gene id: 89673:G6PC3
uniprot id: A0A6J2M8U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

89673:CSTB
gene id: 89673:CSTB
uniprot id: A0A6J2L2H7
names: Similarity
messages: Belongs to the cystatin family.

89673:FAT4
gene id: 89673:FAT4
uniprot id: A0A6J2MBE5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114514088
gene id: 89673:LOC114514088
uniprot id: A0A6J2NB61
uniprot id: A0A7E6D842
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PARI family.
messages: Cytoplasm
messages: Nucleus

89673:ZNF446
gene id: 89673:ZNF446
uniprot id: A0A6J2N8K8
uniprot id: A0A7E6CQR5
uniprot id: A0A7E6CR78
uniprot id: A0A7E6CTF8
names: Subcellular Location Annotation
messages: Nucleus

89673:COL4A5
gene id: 89673:COL4A5
uniprot id: A0A7E6D039
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

89673:EPDR1
gene id: 89673:EPDR1
uniprot id: A0A6J2MPY2
uniprot id: A0A6J2MUA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ependymin family.
messages: Binds anionic lipids and gangliosides at acidic pH.
messages: Lysosome lumen

89673:LSM7
gene id: 89673:LSM7
uniprot id: A0A6J2M9B4
uniprot id: A0A7E6EAU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

89673:HCN1
gene id: 89673:HCN1
uniprot id: A0A6J2MH81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

89673:XPR1
gene id: 89673:XPR1
uniprot id: A0A6J2N3F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYG1 (TC 2.A.94) family.
messages: Membrane

89673:COL18A1
gene id: 89673:COL18A1
uniprot id: A0A7E6D2E5
uniprot id: A0A7E6D2Z5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114493418
gene id: 89673:LOC114493418
uniprot id: A0A7E6CRB5
names: Similarity
messages: Belongs to the serpin family.

89673:AGT
gene id: 89673:AGT
uniprot id: A0A7E6D0Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the serpin family.
messages: Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis.
messages: Secreted
messages: Stimulates aldosterone release.

89673:TCF7
gene id: 89673:TCF7
uniprot id: A0A6J2MVZ7
uniprot id: A0A6J2MXL2
uniprot id: A0A6J2MXM5
uniprot id: A0A6J2N262
uniprot id: A0A6J2N2Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

89673:LOC114505054
gene id: 89673:LOC114505054
uniprot id: A0A7E6D0D9
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

89673:LOC114510949
gene id: 89673:LOC114510949
uniprot id: A0A7E6CS42
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

89673:TMEM255A
gene id: 89673:TMEM255A
uniprot id: A0A6J2MEQ8
uniprot id: A0A6J2MGH9
uniprot id: A0A6J2MKM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM255 family.
messages: Membrane

89673:LOC114492536
gene id: 89673:LOC114492536
uniprot id: A0A6J2L5F6
names: Similarity
messages: Belongs to the UPF0547 family.

89673:TMEM131
gene id: 89673:TMEM131
uniprot id: A0A6J2M670
uniprot id: A0A7E6E4I4
names: Similarity
messages: Belongs to the TMEM131 family.

89673:SLC28A2
gene id: 89673:SLC28A2
uniprot id: A0A7E6EBT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

89673:LOC114503641
gene id: 89673:LOC114503641
uniprot id: A0A6J2MCS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:AGTR2
gene id: 89673:AGTR2
uniprot id: A0A6J2MLH0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with MTUS1.
messages: Membrane

89673:CAPRIN2
gene id: 89673:CAPRIN2
uniprot id: A0A6J2N6K2
uniprot id: A0A6J2N6K4
uniprot id: A0A6J2N8N8
uniprot id: A0A6J2ND70
uniprot id: A0A7E6D733
uniprot id: A0A7E6D738
uniprot id: A0A7E6D743
uniprot id: A0A7E6D798
uniprot id: A0A7E6D7T8
names: Similarity
messages: Belongs to the caprin family.

89673:CPXM2
gene id: 89673:CPXM2
uniprot id: A0A6J2LNY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

89673:LOC114496656
gene id: 89673:LOC114496656
uniprot id: A0A6J2LQ27
uniprot id: A0A7E6DRJ8
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

89673:LOC114500259
gene id: 89673:LOC114500259
uniprot id: A0A6J2M0A5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114509804
gene id: 89673:LOC114509804
uniprot id: A0A6J2N1L7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114500222
gene id: 89673:LOC114500222
uniprot id: A0A6J2LY58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:DYNLT1
gene id: 89673:DYNLT1
uniprot id: A0A6J2LH46
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

89673:LOC114490026
gene id: 89673:LOC114490026
uniprot id: A0A6J2KWX5
names: Function
names: Subunit
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

89673:ATP4A
gene id: 89673:ATP4A
uniprot id: A0A6J2N2Y8
uniprot id: A0A7E6CPU7
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Membrane

89673:CACNA1G
gene id: 89673:CACNA1G
uniprot id: A0A6J2MCX4
uniprot id: A0A6J2MF05
uniprot id: A0A6J2MF11
uniprot id: A0A6J2MF14
uniprot id: A0A6J2MF16
uniprot id: A0A6J2MF17
uniprot id: A0A6J2MF23
uniprot id: A0A6J2MI47
uniprot id: A0A6J2MI78
uniprot id: A0A7E6EDG7
uniprot id: A0A7E6EDH4
uniprot id: A0A7E6EE25
uniprot id: A0A7E6EF93
uniprot id: A0A7E6EF95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite negative potentials, and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes.

89673:LOC114511244
gene id: 89673:LOC114511244
uniprot id: A0A7E6CTN2
names: Subcellular Location Annotation
messages: Nucleus

89673:NUMBL
gene id: 89673:NUMBL
uniprot id: A0A6J2MYS6
uniprot id: A0A6J2N0H6
names: Function
messages: Plays a role in the process of neurogenesis.

89673:LOC114513262
gene id: 89673:LOC114513262
uniprot id: A0A6J2N8Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:MS4A15
gene id: 89673:MS4A15
uniprot id: A0A6J2M1X7
names: Similarity
messages: Belongs to the MS4A family.

89673:HMOX1
gene id: 89673:HMOX1
uniprot id: A0A6J2NEV7
names: Similarity
messages: Belongs to the heme oxygenase family.

89673:SMAD6
gene id: 89673:SMAD6
uniprot id: A0A6J2L736
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

89673:ISOC2
gene id: 89673:ISOC2
uniprot id: A0A6J2N5C6
names: Similarity
messages: Belongs to the isochorismatase family.

89673:MFNG
gene id: 89673:MFNG
uniprot id: A0A6J2N7Q5
uniprot id: A0A7E6D861
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114505252
gene id: 89673:LOC114505252
uniprot id: A0A7E6CZS1
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

89673:PTGES3L
gene id: 89673:PTGES3L
uniprot id: A0A6J2M974
uniprot id: A0A6J2MB12
uniprot id: A0A7E6EEU4
uniprot id: A0A7E6EFN2
names: Similarity
messages: Belongs to the p23/wos2 family.

89673:ACE
gene id: 89673:ACE
uniprot id: A0A6J2M647
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M2 family.
messages: Binds 2 Zn(2+) ions per subunit.

89673:LOC118496709
gene id: 89673:LOC118496709
uniprot id: A0A7E6CDT4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

89673:UBE2F
gene id: 89673:UBE2F
uniprot id: A0A6J2LIF8
uniprot id: A0A7E6DHI3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

89673:TLX2
gene id: 89673:TLX2
uniprot id: A0A6J2M3X4
names: Subcellular Location Annotation
messages: Nucleus

89673:TSPAN13
gene id: 89673:TSPAN13
uniprot id: A0A6J2MP09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

89673:CDC42BPB
gene id: 89673:CDC42BPB
uniprot id: A0A7E6CSL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
messages: Cytoplasm
messages: lamellipodium

89673:TMEM53
gene id: 89673:TMEM53
uniprot id: A0A6J2LLY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM53 family.
messages: Membrane
messages: Nucleus outer membrane

89673:FICD
gene id: 89673:FICD
uniprot id: A0A6J2MU03
names: Similarity
messages: Belongs to the fic family.

89673:CLCN2
gene id: 89673:CLCN2
uniprot id: A0A6J2L4X7
uniprot id: A0A7E6D352
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-2/CLCN2 subfamily.
messages: Cell membrane
messages: Membrane

89673:LOC114511303
gene id: 89673:LOC114511303
uniprot id: A0A6J2N031
uniprot id: A0A6J2N1U3
names: Similarity
messages: Belongs to the AAA ATPase family.

89673:ATG4A
gene id: 89673:ATG4A
uniprot id: A0A6J2MLM1
uniprot id: A0A7E6D2X2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

89673:ATP6V1H
gene id: 89673:ATP6V1H
uniprot id: A0A6J2M2B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase H subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

89673:SUCLA2
gene id: 89673:SUCLA2
uniprot id: A0A6J2MS98
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
messages: Belongs to the succinate/malate CoA ligase beta subunit family. ATP-specific subunit beta subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for ATP.
messages: Mitochondrion

89673:ANKRD13D
gene id: 89673:ANKRD13D
uniprot id: A0A6J2LVW3
uniprot id: A0A7E6E2S0
uniprot id: A0A7E6E3N3
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

89673:LOC118499536
gene id: 89673:LOC118499536
uniprot id: A0A7E6DBL2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

89673:STX12
gene id: 89673:STX12
uniprot id: A0A6J2LLT9
names: Similarity
messages: Belongs to the syntaxin family.

89673:RPS15
gene id: 89673:RPS15
uniprot id: A0A6J2M8H2
uniprot id: A0A7E6E9H6
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Component of the small ribosomal subunit.

89673:CPSF4L
gene id: 89673:CPSF4L
uniprot id: A0A6J2MEP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex.
messages: Nucleus

89673:IGFBP5
gene id: 89673:IGFBP5
uniprot id: A0A6J2LBV6
uniprot id: A0A6J2LGV0
names: Caution
names: Function
names: Subcellular Location Annotation
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:NUP210L
gene id: 89673:NUP210L
uniprot id: A0A7E6CW54
names: Similarity
messages: Belongs to the NUP210 family.

89673:LOC114499106
gene id: 89673:LOC114499106
uniprot id: A0A7E6E241
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:RIOK2
gene id: 89673:RIOK2
uniprot id: A0A6J2MQ95
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

89673:AHSA1
gene id: 89673:AHSA1
uniprot id: A0A6J2LCU0
uniprot id: A0A7E6CNS1
names: Similarity
messages: Belongs to the AHA1 family.

89673:LAMP1
gene id: 89673:LAMP1
uniprot id: A0A6J2MRT5
uniprot id: A0A7E6CKF5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lysosome membrane
messages: Membrane

89673:CTBS
gene id: 89673:CTBS
uniprot id: A0A6J2LR53
uniprot id: A0A7E6DSW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 18 family.
messages: Lysosome

89673:ABITRAM
gene id: 89673:ABITRAM
uniprot id: A0A6J2M6X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABITRAM family.
messages: growth cone
messages: lamellipodium

89673:WIF1
gene id: 89673:WIF1
uniprot id: A0A6J2NFR9
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:LOC114488279
gene id: 89673:LOC114488279
uniprot id: A0A6J2KUP2
names: Function
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.
messages: Metallothioneins have a high content of cysteine residues that bind various heavy metals.

89673:CTNND2
gene id: 89673:CTNND2
uniprot id: A0A6J2M425
uniprot id: A0A7E6DA41
uniprot id: A0A7E6DAC4
uniprot id: A0A7E6DB49
uniprot id: A0A7E6DCY1
names: Similarity
messages: Belongs to the beta-catenin family.

89673:MSH4
gene id: 89673:MSH4
uniprot id: A0A7E6DT83
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.

89673:GRK1
gene id: 89673:GRK1
uniprot id: A0A6J2MXS2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

89673:OXER1
gene id: 89673:OXER1
uniprot id: A0A7E6DX46
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:PEX19
gene id: 89673:PEX19
uniprot id: A0A7E6CXW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxin-19 family.
messages: Interacts with a broad range of peroxisomal membrane proteins, including PEX3, PEX10, PEX11A, PEX11B, PEX12, PEX13, PEX14 and PEX16, PXMP2/PMP22, PXMP4/PMP24, SLC25A17/PMP34, ABCD1/ALDP, ABCD2/ALDRP, and ABCD3/PMP70. Also interacts with the tumor suppressor CDKN2A/p19ARF.
messages: Membrane
messages: Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53.
messages: Peroxisome membrane

89673:LOC114509847
gene id: 89673:LOC114509847
uniprot id: A0A6J2MX99
uniprot id: A0A7E6CS54
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Refilin family.
messages: Interacts with FLNA and FLNB.
messages: cytoskeleton

89673:WDR24
gene id: 89673:WDR24
uniprot id: A0A6J2M589
uniprot id: A0A7E6DCV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR24 family.
messages: Lysosome membrane

89673:CHRNB3
gene id: 89673:CHRNB3
uniprot id: A0A6J2MXL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

89673:LAMTOR2
gene id: 89673:LAMTOR2
uniprot id: A0A6J2KT04
uniprot id: A0A7E6CXC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GAMAD family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

89673:NKX3-1
gene id: 89673:NKX3-1
uniprot id: A0A6J2MET0
names: Subcellular Location Annotation
messages: Nucleus

89673:PTHLH
gene id: 89673:PTHLH
uniprot id: A0A6J2NHC0
uniprot id: A0A7E6D752
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the parathyroid hormone family.
messages: Cytoplasm
messages: Neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Required for skeletal homeostasis. Promotes mammary mesenchyme differentiation and bud outgrowth by modulating mesenchymal cell responsiveness to BMPs. Up-regulates BMPR1A expression in the mammary mesenchyme and this increases the sensitivity of these cells to BMPs and allows them to respond to BMP4 in a paracrine and/or autocrine fashion. BMP4 signaling in the mesenchyme, in turn, triggers epithelial outgrowth and augments MSX2 expression, which causes the mammary mesenchyme to inhibit hair follicle formation within the nipple sheath.
messages: Nucleus
messages: Osteostatin is a potent inhibitor of osteoclastic bone resorption.
messages: PTHrP interacts with PTH1R (via N-terminal extracellular domain).
messages: Secreted
messages: There are several secretory forms, including osteostatin, arising from endoproteolytic cleavage of the initial translation product. Each of these secretory forms is believed to have one or more of its own receptors that mediates the normal paracrine, autocrine and endocrine actions.

89673:LOC114500218
gene id: 89673:LOC114500218
uniprot id: A0A6J2M051
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:HCRTR1
gene id: 89673:HCRTR1
uniprot id: A0A6J2LPN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:LOC114512243
gene id: 89673:LOC114512243
uniprot id: A0A6J2NAH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TBCE
gene id: 89673:TBCE
uniprot id: A0A6J2N543
uniprot id: A0A7E6CY76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCE family.
messages: Cytoplasm

89673:NUDT19
gene id: 89673:NUDT19
uniprot id: A0A6J2KR42
names: Similarity
messages: Belongs to the Nudix hydrolase family.

89673:VEGFC
gene id: 89673:VEGFC
uniprot id: A0A6J2MSK0
uniprot id: A0A7E6CLA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Secreted

89673:CAPN9
gene id: 89673:CAPN9
uniprot id: A0A6J2N5F1
names: Similarity
messages: Belongs to the peptidase C2 family.

89673:TMED9
gene id: 89673:TMED9
uniprot id: A0A6J2N2E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:FERMT3
gene id: 89673:FERMT3
uniprot id: A0A6J2LVI6
names: Similarity
messages: Belongs to the kindlin family.

89673:RPS21
gene id: 89673:RPS21
uniprot id: A0A6J2MQR0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS21 family.
messages: Component of the 40S small ribosomal subunit.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum
messages: cytosol

89673:PLIN4
gene id: 89673:PLIN4
uniprot id: A0A6J2MCM9
names: Similarity
messages: Belongs to the perilipin family.

89673:LOC114506435
gene id: 89673:LOC114506435
uniprot id: A0A7E6DAD7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.

89673:BET1
gene id: 89673:BET1
uniprot id: A0A6J2MMM2
names: Subcellular Location Annotation
messages: Membrane

89673:TRPM7
gene id: 89673:TRPM7
uniprot id: A0A7E6EDD3
uniprot id: A0A7E6EE50
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: In the C-terminal section; belongs to the protein kinase superfamily. Alpha-type protein kinase family. ALPK subfamily.
messages: Membrane

89673:MYLK4
gene id: 89673:MYLK4
uniprot id: A0A7E6DTL0
uniprot id: A0A7E6DU96
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:LHX3
gene id: 89673:LHX3
uniprot id: A0A6J2MXS7
uniprot id: A0A6J2MXT9
names: Subcellular Location Annotation
messages: Nucleus

89673:TUT7
gene id: 89673:TUT7
uniprot id: A0A6J2L5T4
uniprot id: A0A6J2L7Z6
uniprot id: A0A7E6DF80
uniprot id: A0A7E6DF90
uniprot id: A0A7E6DFB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B-like family.
messages: Cytoplasm

89673:IL1RL1
gene id: 89673:IL1RL1
uniprot id: A0A6J2LXY4
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

89673:HPD
gene id: 89673:HPD
uniprot id: A0A6J2N0D2
uniprot id: A0A7E6CRU8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

89673:SLX1A
gene id: 89673:SLX1A
uniprot id: A0A6J2M0Q9
uniprot id: A0A6J2M219
uniprot id: A0A7E6DDQ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLX1 family.
messages: Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products.
messages: Forms a heterodimer with SLX4.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

89673:PRR15
gene id: 89673:PRR15
uniprot id: A0A6J2MNS8
names: Similarity
messages: Belongs to the PRR15 family.

89673:PALM3
gene id: 89673:PALM3
uniprot id: A0A7E6E9D7
uniprot id: A0A7E6EA65
uniprot id: A0A7E6EAF3
uniprot id: A0A7E6EB16
names: Similarity
messages: Belongs to the paralemmin family.

89673:BRAF
gene id: 89673:BRAF
uniprot id: A0A6J2MN37
uniprot id: A0A7E6CIQ1
uniprot id: A0A7E6CIT1
uniprot id: A0A7E6CKY5
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

89673:AQR
gene id: 89673:AQR
uniprot id: A0A6J2L3R1
uniprot id: A0A7E6E7T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CWF11 family.
messages: Identified in the spliceosome C complex. Component of the XAB2 complex, a multimeric protein complex composed of XAB2, PRPF19, AQR, ZNF830, ISY1, and PPIE.
messages: Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.
messages: Nucleus

89673:LOC114490165
gene id: 89673:LOC114490165
uniprot id: A0A6J2KXF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114499049
gene id: 89673:LOC114499049
uniprot id: A0A6J2LUV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114502438
gene id: 89673:LOC114502438
uniprot id: A0A6J2MA44
names: Similarity
messages: Belongs to the intermediate filament family.

89673:CACNA1E
gene id: 89673:CACNA1E
uniprot id: A0A7E6CY79
uniprot id: A0A7E6CYM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents.

89673:LOC114496611
gene id: 89673:LOC114496611
uniprot id: A0A6J2LL16
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

89673:PRRC1
gene id: 89673:PRRC1
uniprot id: A0A6J2MPR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRRC1 family.
messages: Golgi apparatus

89673:KMT2D
gene id: 89673:KMT2D
uniprot id: A0A6J2N6X0
uniprot id: A0A7E6D6S5
uniprot id: A0A7E6D6T4
uniprot id: A0A7E6D6Z2
uniprot id: A0A7E6D6Z9
uniprot id: A0A7E6D7I1
uniprot id: A0A7E6D7I7
uniprot id: A0A7E6D9Q5
uniprot id: A0A7E6D9R0
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114501818
gene id: 89673:LOC114501818
uniprot id: A0A6J2M4B8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

89673:DTYMK
gene id: 89673:DTYMK
uniprot id: A0A6J2LJK9
names: Similarity
messages: Belongs to the thymidylate kinase family.

89673:TAFA5
gene id: 89673:TAFA5
uniprot id: A0A7E6D8N2
uniprot id: A0A7E6DBK4
names: Similarity
messages: Belongs to the TAFA family.

89673:CPSF6
gene id: 89673:CPSF6
uniprot id: A0A6J2N4R5
uniprot id: A0A6J2N6P9
uniprot id: A0A6J2NBB7
uniprot id: A0A6J2NC07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CPSF6/7 family.
messages: Nucleus

89673:OLFML1
gene id: 89673:OLFML1
uniprot id: A0A6J2LSV0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:CLU
gene id: 89673:CLU
uniprot id: A0A6J2ME68
uniprot id: A0A7E6E8H1
uniprot id: A0A7E6EAH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Antiparallel disulfide-linked heterodimer of an alpha chain and a beta chain. Self-associates and forms higher oligomers.
messages: Belongs to the clusterin family.
messages: Endoplasmic reticulum
messages: Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins.
messages: Membrane
messages: Microsome
messages: Mitochondrion membrane
messages: Nucleus
messages: Secreted
messages: chromaffin granule
messages: cytosol
messages: perinuclear region

89673:AATF
gene id: 89673:AATF
uniprot id: A0A6J2MCD4
uniprot id: A0A7E6ED50
names: Similarity
messages: Belongs to the AATF family.

89673:DSC1
gene id: 89673:DSC1
uniprot id: A0A6J2MJY2
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

89673:KCND3
gene id: 89673:KCND3
uniprot id: A0A6J2KWN1
uniprot id: A0A7E6D0I0
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

89673:UBE2D2
gene id: 89673:UBE2D2
uniprot id: A0A6J2MYF9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

89673:GOLPH3L
gene id: 89673:GOLPH3L
uniprot id: A0A6J2KT35
uniprot id: A0A6J2KWX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

89673:WSCD1
gene id: 89673:WSCD1
uniprot id: A0A6J2NDE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WSCD family.
messages: Golgi apparatus membrane
messages: Sialate:O-sulfotransferase which catalyzes 8-O-sulfation at the Sia-glycan level using 3'-phosphoadenosine 5'-phosphosulfate (PAPS) as a donor, forming 8-O-sulfated Sia (Sia8S)-glycans.

89673:LOC114503332
gene id: 89673:LOC114503332
uniprot id: A0A7E6EDL4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL27 family.

89673:LOC114496711
gene id: 89673:LOC114496711
uniprot id: A0A6J2LKD8
names: Similarity
messages: Belongs to the TMEM14 family.

89673:NR1H4
gene id: 89673:NR1H4
uniprot id: A0A6J2N8X7
uniprot id: A0A6J2N9A6
uniprot id: A0A6J2NDY3
uniprot id: A0A6J2NEJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

89673:ORMDL1
gene id: 89673:ORMDL1
uniprot id: A0A6J2LCK4
uniprot id: A0A7E6DJA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

89673:LOC114510576
gene id: 89673:LOC114510576
uniprot id: A0A7E6CN14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:LOC114500433
gene id: 89673:LOC114500433
uniprot id: A0A6J2LYV7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:AGTPBP1
gene id: 89673:AGTPBP1
uniprot id: A0A6J2LS84
uniprot id: A0A6J2LWD6
uniprot id: A0A7E6DF84
uniprot id: A0A7E6DFB3
uniprot id: A0A7E6DFC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

89673:LOC118500943
gene id: 89673:LOC118500943
uniprot id: A0A7E6DW42
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

89673:SORCS1
gene id: 89673:SORCS1
uniprot id: A0A6J2LME5
uniprot id: A0A6J2LNR2
uniprot id: A0A6J2LST7
uniprot id: A0A7E6DVB0
uniprot id: A0A7E6DW96
names: Similarity
messages: Belongs to the VPS10-related sortilin family. SORCS subfamily.

89673:LOC114512681
gene id: 89673:LOC114512681
uniprot id: A0A6J2NB64
names: Similarity
messages: Belongs to the actin family.

89673:HOXB4
gene id: 89673:HOXB4
uniprot id: A0A6J2MEX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

89673:BCL2A1
gene id: 89673:BCL2A1
uniprot id: A0A6J2KSP3
names: Similarity
messages: Belongs to the Bcl-2 family.

89673:AVPR1A
gene id: 89673:AVPR1A
uniprot id: A0A6J2NBS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.

89673:EPS8
gene id: 89673:EPS8
uniprot id: A0A6J2N5V1
uniprot id: A0A7E6D7D5
uniprot id: A0A7E6D7E0
uniprot id: A0A7E6D7G7
uniprot id: A0A7E6D7H1
uniprot id: A0A7E6D7K5
uniprot id: A0A7E6D7L0
uniprot id: A0A7E6D866
uniprot id: A0A7E6D870
uniprot id: A0A7E6DAB9
names: Similarity
messages: Belongs to the EPS8 family.

89673:ARL6IP5
gene id: 89673:ARL6IP5
uniprot id: A0A6J2M4E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

89673:FAM166A
gene id: 89673:FAM166A
uniprot id: A0A6J2LAS2
names: Similarity
messages: Belongs to the CIMIP2 family.

89673:PLXNB3
gene id: 89673:PLXNB3
uniprot id: A0A6J2MFP0
uniprot id: A0A7E6D0B6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:SPEN
gene id: 89673:SPEN
uniprot id: A0A6J2LJX8
names: Similarity
messages: Belongs to the RRM Spen family.

89673:TAFA2
gene id: 89673:TAFA2
uniprot id: A0A6J2N9S8
names: Similarity
messages: Belongs to the TAFA family.

89673:GREB1
gene id: 89673:GREB1
uniprot id: A0A6J2M3M4
uniprot id: A0A7E6DWK7
uniprot id: A0A7E6DXU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GREB1 family.
messages: Membrane

89673:TAF5
gene id: 89673:TAF5
uniprot id: A0A6J2LK98
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

89673:LOC114500361
gene id: 89673:LOC114500361
uniprot id: A0A6J2LYM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCC3 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex), mediating cytochrome b recruitment and probably stabilization within the complex. Thereby, plays an important role in ATP production by mitochondria. Cardiolipin-binding protein, it may also control the cardiolipin composition of mitochondria membranes and their morphology.

89673:LOC114490123
gene id: 89673:LOC114490123
uniprot id: A0A6J2L2K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the C19orf12 family.
messages: Mitochondrion membrane

89673:ANAPC2
gene id: 89673:ANAPC2
uniprot id: A0A6J2M214
names: Similarity
messages: Belongs to the cullin family.

89673:LOC114500614
gene id: 89673:LOC114500614
uniprot id: A0A6J2M4G9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SLC22A18
gene id: 89673:SLC22A18
uniprot id: A0A6J2M341
uniprot id: A0A7E6E2G7
names: Subcellular Location Annotation
messages: Membrane

89673:PPFIA2
gene id: 89673:PPFIA2
uniprot id: A0A6J2N901
uniprot id: A0A6J2NE13
uniprot id: A0A7E6D5F8
uniprot id: A0A7E6D5G3
uniprot id: A0A7E6D5G8
uniprot id: A0A7E6D5H6
uniprot id: A0A7E6D5H8
uniprot id: A0A7E6D5J8
uniprot id: A0A7E6D5K2
uniprot id: A0A7E6D5K9
uniprot id: A0A7E6D5L4
uniprot id: A0A7E6D5L9
uniprot id: A0A7E6D650
uniprot id: A0A7E6D655
uniprot id: A0A7E6D660
uniprot id: A0A7E6D665
uniprot id: A0A7E6D8B2
uniprot id: A0A7E6D8B7
uniprot id: A0A7E6D8C4
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

89673:STT3B
gene id: 89673:STT3B
uniprot id: A0A6J2M4S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

89673:TSEN15
gene id: 89673:TSEN15
uniprot id: A0A6J2N933
uniprot id: A0A7E6CXL5
uniprot id: A0A7E6CXP7
uniprot id: A0A7E6CY41
uniprot id: A0A7E6CYI8
names: Similarity
messages: Belongs to the SEN15 family.

89673:LOC114509365
gene id: 89673:LOC114509365
uniprot id: A0A6J2N0E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RBM8A family.
messages: Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
messages: Cytoplasm
messages: Heterodimer with MAGOH. Part of the mRNA splicing-dependent exon junction complex (EJC) complex; the core complex contains CASC3, EIF4A3, MAGOH and RBM8A.
messages: Nucleus
messages: Nucleus speckle

89673:LOC114506081
gene id: 89673:LOC114506081
uniprot id: A0A6J2MN98
names: Similarity
messages: Belongs to the vasopressin/oxytocin family.

89673:EBF3
gene id: 89673:EBF3
uniprot id: A0A6J2LPE0
uniprot id: A0A6J2LRL7
uniprot id: A0A6J2LUU8
uniprot id: A0A6J2LUV8
uniprot id: A0A7E6DVT8
uniprot id: A0A7E6DVZ7
uniprot id: A0A7E6DW02
uniprot id: A0A7E6DWE0
uniprot id: A0A7E6DWE5
uniprot id: A0A7E6DWE9
uniprot id: A0A7E6DWS3
uniprot id: A0A7E6DWS9
uniprot id: A0A7E6DX78
uniprot id: A0A7E6DX82
uniprot id: A0A7E6DX87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

89673:SPTBN2
gene id: 89673:SPTBN2
uniprot id: A0A7E6E3M0
uniprot id: A0A7E6E3M6
names: Similarity
messages: Belongs to the spectrin family.

89673:LOC114498856
gene id: 89673:LOC114498856
uniprot id: A0A7E6E2U0
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

89673:SHANK2
gene id: 89673:SHANK2
uniprot id: A0A6J2KYI8
uniprot id: A0A7E6E2E0
uniprot id: A0A7E6E3W1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.
messages: Postsynaptic density

89673:SUMO1
gene id: 89673:SUMO1
uniprot id: A0A6J2LEG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

89673:LOC114499791
gene id: 89673:LOC114499791
uniprot id: A0A7E6DXP1
names: Subcellular Location Annotation
messages: Nucleus

89673:DLX2
gene id: 89673:DLX2
uniprot id: A0A6J2LF98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

89673:PAX9
gene id: 89673:PAX9
uniprot id: A0A6J2L6C0
uniprot id: A0A7E6E1Q9
names: Subcellular Location Annotation
messages: Nucleus

89673:PLP2
gene id: 89673:PLP2
uniprot id: A0A6J2MEG2
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114506980
gene id: 89673:LOC114506980
uniprot id: A0A7E6CGK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
messages: Forms a homohexamer that can probably bind six kinase subunits.

89673:KCNC4
gene id: 89673:KCNC4
uniprot id: A0A6J2KWJ1
uniprot id: A0A6J2KY96
uniprot id: A0A7E6CXJ7
names: Subcellular Location Annotation
messages: Membrane

89673:IFNB1
gene id: 89673:IFNB1
uniprot id: A0A6J2N430
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

89673:TSPO
gene id: 89673:TSPO
uniprot id: A0A6J2NA12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

89673:PPP1R3B
gene id: 89673:PPP1R3B
uniprot id: A0A6J2MTH3
uniprot id: A0A6J2MYG8
names: Subunit
messages: Interacts with glycogen, PPP1CC catalytic subunit of PP1 and PYGL. Associates with glycogen particles. Forms complexes with debranching enzyme, glycogen phosphorylase, glycogen synthase and phosphorylase kinase which is necessary for its regulation of PP1 activity.

89673:LOC114511582
gene id: 89673:LOC114511582
uniprot id: A0A6J2N0Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lambda interferon family.
messages: Secreted

89673:ARPC2
gene id: 89673:ARPC2
uniprot id: A0A6J2LI02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC2 family.
messages: Cell projection
messages: Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC. Interacts with SHANK3; the interaction probably mediates the association of SHANK3 with the Arp2/3 complex.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton
messages: synaptosome

89673:TRAPPC3L
gene id: 89673:TRAPPC3L
uniprot id: A0A6J2LI74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Homodimer.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: cis-Golgi network

89673:GDF7
gene id: 89673:GDF7
uniprot id: A0A6J2M2E0
names: Similarity
messages: Belongs to the TGF-beta family.

89673:CNOT10
gene id: 89673:CNOT10
uniprot id: A0A6J2M293
uniprot id: A0A6J2M7X9
uniprot id: A0A7E6E4Z9
uniprot id: A0A7E6E545
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT10 family.
messages: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.
messages: Cytoplasm
messages: Nucleus

89673:NDUFC2
gene id: 89673:NDUFC2
uniprot id: A0A6J2M152
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFC2 subunit family.
messages: Mitochondrion inner membrane

89673:SLC12A4
gene id: 89673:SLC12A4
uniprot id: A0A6J2KQ23
uniprot id: A0A6J2KSB4
uniprot id: A0A6J2KW76
uniprot id: A0A7E6CLY3
uniprot id: A0A7E6CP60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

89673:EVA1B
gene id: 89673:EVA1B
uniprot id: A0A6J2LS14
names: Similarity
messages: Belongs to the EVA1 family.

89673:TXK
gene id: 89673:TXK
uniprot id: A0A7E6DA72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

89673:ZCCHC8
gene id: 89673:ZCCHC8
uniprot id: A0A6J2MWE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZCCHC8 family.
messages: nucleoplasm

89673:TRIM71
gene id: 89673:TRIM71
uniprot id: A0A6J2M4B9
names: Similarity
messages: Belongs to the TRIM/RBCC family.

89673:POFUT1
gene id: 89673:POFUT1
uniprot id: A0A6J2MMJ3
names: Similarity
messages: Belongs to the glycosyltransferase 65 family.

89673:TPRG1
gene id: 89673:TPRG1
uniprot id: A0A6J2L3S5
names: Similarity
messages: Belongs to the TPRG1 family.

89673:THAP1
gene id: 89673:THAP1
uniprot id: A0A6J2MSM8
uniprot id: A0A7E6CKJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the THAP1 family.
messages: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes.
messages: Interacts with PAWR. Component of a THAP1/THAP3-HCFC1-OGT complex that contains, either THAP1 or THAP3, HCFC1 and OGT. Interacts with OGT. Interacts (via the HBM) with HCFC1 (via the Kelch-repeat domain); the interaction recruits HCFC1 to the RRM1 promoter.
messages: nucleoplasm

89673:SENP5
gene id: 89673:SENP5
uniprot id: A0A6J2L064
uniprot id: A0A6J2L2H0
uniprot id: A0A6J2L4H0
uniprot id: A0A7E6D4L0
uniprot id: A0A7E6D4P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C48 family.
messages: nucleolus

89673:NUDT21
gene id: 89673:NUDT21
uniprot id: A0A6J2KU64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family. CPSF5 subfamily.
messages: Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.
messages: Cytoplasm
messages: Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.
messages: Nucleus

89673:SLC25A4
gene id: 89673:SLC25A4
uniprot id: A0A6J2MSX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

89673:DUSP29
gene id: 89673:DUSP29
uniprot id: A0A6J2LQK8
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

89673:TRPM4
gene id: 89673:TRPM4
uniprot id: A0A6J2N0L4
uniprot id: A0A7E6CN97
uniprot id: A0A7E6CQN1
names: Subcellular Location Annotation
messages: Membrane

89673:RBM42
gene id: 89673:RBM42
uniprot id: A0A6J2MZR6
uniprot id: A0A6J2N1F1
uniprot id: A0A7E6CRI1
uniprot id: A0A7E6CRK2
names: Similarity
messages: Belongs to the RRM RBM42 family.

89673:URAD
gene id: 89673:URAD
uniprot id: A0A6J2KZW6
names: Function
names: Similarity
messages: Belongs to the OHCU decarboxylase family.
messages: Catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin.

89673:RELT
gene id: 89673:RELT
uniprot id: A0A7E6E0C0
uniprot id: A0A7E6E108
names: Similarity
messages: Belongs to the RELT family.

89673:ADGRG3
gene id: 89673:ADGRG3
uniprot id: A0A6J2KTA0
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114498925
gene id: 89673:LOC114498925
uniprot id: A0A6J2LXM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TMEM233
gene id: 89673:TMEM233
uniprot id: A0A6J2MWT6
uniprot id: A0A7E6CRW5
names: Similarity
messages: Belongs to the CD225/Dispanin family.

89673:LOC114504243
gene id: 89673:LOC114504243
uniprot id: A0A6J2MII0
names: Similarity
messages: Belongs to the Schlafen family. Subgroup III subfamily.

89673:PDZK1IP1
gene id: 89673:PDZK1IP1
uniprot id: A0A6J2LN84
uniprot id: A0A7E6DRX6
names: Subcellular Location Annotation
messages: Membrane

89673:GGH
gene id: 89673:GGH
uniprot id: A0A6J2ND50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C26 family.
messages: extracellular space

89673:ORM1
gene id: 89673:ORM1
uniprot id: A0A6J2NEY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

89673:ATP5MC3
gene id: 89673:ATP5MC3
uniprot id: A0A7E6DJB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

89673:CELSR3
gene id: 89673:CELSR3
uniprot id: A0A7E6E3W6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor that may have an important role in cell/cell signaling during nervous system formation.

89673:TDRD9
gene id: 89673:TDRD9
uniprot id: A0A7E6CSW0
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily.

89673:PSMA7
gene id: 89673:PSMA7
uniprot id: A0A6J2MQ47
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

89673:LOC114508003
gene id: 89673:LOC114508003
uniprot id: A0A7E6CL39
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

89673:LOC114503696
gene id: 89673:LOC114503696
uniprot id: A0A7E6EAF0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:MAF1
gene id: 89673:MAF1
uniprot id: A0A6J2NCE0
uniprot id: A0A6J2NHL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAF1 family.
messages: Element of the TORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.
messages: Nucleus

89673:PYGM
gene id: 89673:PYGM
uniprot id: A0A6J2LZI8
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

89673:TIMM44
gene id: 89673:TIMM44
uniprot id: A0A6J2NJF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tim44 family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion inner membrane

89673:MGAT1
gene id: 89673:MGAT1
uniprot id: A0A6J2MW76
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.
messages: Membrane
messages: The cofactor is mostly bound to the substrate.

89673:OCRL
gene id: 89673:OCRL
uniprot id: A0A7E6D0U4
uniprot id: A0A7E6D1S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: phagosome membrane

89673:LOC114510000
gene id: 89673:LOC114510000
uniprot id: A0A6J2N2H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

89673:LOC114511032
gene id: 89673:LOC114511032
uniprot id: A0A6J2N0Q2
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

89673:LOC114492926
gene id: 89673:LOC114492926
uniprot id: A0A6J2LCP4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Membrane

89673:PPP1CA
gene id: 89673:PPP1CA
uniprot id: A0A6J2LZB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: nucleolus
messages: nucleoplasm

89673:MRPL4
gene id: 89673:MRPL4
uniprot id: A0A6J2MB16
uniprot id: A0A7E6EB92
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

89673:LOC114488219
gene id: 89673:LOC114488219
uniprot id: A0A6J2KQI3
uniprot id: A0A7E6CLY1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
messages: Homodimer; disulfide-linked.
messages: Membrane

89673:IKBKB
gene id: 89673:IKBKB
uniprot id: A0A6J2MRQ5
uniprot id: A0A7E6CKK7
uniprot id: A0A7E6CKK9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

89673:LOC114507832
gene id: 89673:LOC114507832
uniprot id: A0A6J2MQ73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:BARX1
gene id: 89673:BARX1
uniprot id: A0A6J2N648
names: Subcellular Location Annotation
messages: Nucleus

89673:ATP6V1C2
gene id: 89673:ATP6V1C2
uniprot id: A0A6J2M2I9
uniprot id: A0A7E6DWE2
uniprot id: A0A7E6DWJ7
uniprot id: A0A7E6DXD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits.

89673:COPZ1
gene id: 89673:COPZ1
uniprot id: A0A6J2NBS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

89673:SERPINI1
gene id: 89673:SERPINI1
uniprot id: A0A6J2L247
names: Similarity
messages: Belongs to the serpin family.

89673:TMEM132B
gene id: 89673:TMEM132B
uniprot id: A0A7E6CUV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

89673:JUNB
gene id: 89673:JUNB
uniprot id: A0A6J2MDS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

89673:COLGALT2
gene id: 89673:COLGALT2
uniprot id: A0A6J2N295
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

89673:FAM160B2
gene id: 89673:FAM160B2
uniprot id: A0A6J2MBE7
names: Similarity
messages: Belongs to the FHIP family.

89673:KCNK18
gene id: 89673:KCNK18
uniprot id: A0A6J2LLV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

89673:LOC114489087
gene id: 89673:LOC114489087
uniprot id: A0A7E6CWP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGR2 family.
messages: Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.
messages: Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation.
messages: Mitochondrion inner membrane

89673:FAM120B
gene id: 89673:FAM120B
uniprot id: A0A6J2L0I2
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

89673:HS3ST5
gene id: 89673:HS3ST5
uniprot id: A0A6J2LDG2
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

89673:BCAN
gene id: 89673:BCAN
uniprot id: A0A7E6CWJ2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aggrecan/versican proteoglycan family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

89673:HSF1
gene id: 89673:HSF1
uniprot id: A0A6J2NCL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

89673:AOC1
gene id: 89673:AOC1
uniprot id: A0A7E6CJ76
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

89673:CENPL
gene id: 89673:CENPL
uniprot id: A0A6J2N4C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-L/IML3 family.
messages: Nucleus

89673:LOC114513408
gene id: 89673:LOC114513408
uniprot id: A0A6J2N7I6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG10 glucosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:KLHL15
gene id: 89673:KLHL15
uniprot id: A0A6J2MJ47
names: Subcellular Location Annotation
messages: Nucleus

89673:TMEM211
gene id: 89673:TMEM211
uniprot id: A0A6J2N007
names: Subcellular Location Annotation
messages: Membrane

89673:IGFBP1
gene id: 89673:IGFBP1
uniprot id: A0A7E6CJ45
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds equally well IGF1 and IGF2.
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:LOC114495208
gene id: 89673:LOC114495208
uniprot id: A0A7E6DIP1
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

89673:AMT
gene id: 89673:AMT
uniprot id: A0A6J2M945
uniprot id: A0A7E6E4C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvT family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

89673:ST3GAL4
gene id: 89673:ST3GAL4
uniprot id: A0A6J2MWE8
uniprot id: A0A6J2MY41
uniprot id: A0A6J2N3E0
uniprot id: A0A7E6CU72
uniprot id: A0A7E6CUR8
uniprot id: A0A7E6CV12
uniprot id: A0A7E6CX03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

89673:MRPS18A
gene id: 89673:MRPS18A
uniprot id: A0A6J2LKV1
uniprot id: A0A7E6DM21
uniprot id: A0A7E6DMF6
names: Subcellular Location Annotation
messages: Mitochondrion

89673:HYLS1
gene id: 89673:HYLS1
uniprot id: A0A6J2MUW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HYLS1 family.
messages: centriole
messages: cilium

89673:TOMM20L
gene id: 89673:TOMM20L
uniprot id: A0A6J2L1Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

89673:LOC114493055
gene id: 89673:LOC114493055
uniprot id: A0A6J2L7U9
uniprot id: A0A7E6DS41
uniprot id: A0A7E6DS46
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

89673:PIP4P1
gene id: 89673:PIP4P1
uniprot id: A0A6J2KXB7
uniprot id: A0A6J2L351
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane
messages: phagosome membrane

89673:OSBPL6
gene id: 89673:OSBPL6
uniprot id: A0A6J2LCF8
uniprot id: A0A6J2LDL2
uniprot id: A0A6J2LET4
uniprot id: A0A7E6DJ93
uniprot id: A0A7E6DJ94
uniprot id: A0A7E6DJG3
uniprot id: A0A7E6DJH6
names: Similarity
messages: Belongs to the OSBP family.

89673:LOC114508130
gene id: 89673:LOC114508130
uniprot id: A0A6J2MR07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

89673:SCOC
gene id: 89673:SCOC
uniprot id: A0A6J2M6T8
uniprot id: A0A6J2M857
uniprot id: A0A6J2M8Q2
uniprot id: A0A6J2MBH2
uniprot id: A0A6J2MC35
uniprot id: A0A6J2MC39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCOC family.
messages: Positive regulator of amino acid starvation-induced autophagy.
messages: trans-Golgi network

89673:PLET1
gene id: 89673:PLET1
uniprot id: A0A6J2LUF5
names: Function
messages: Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle.

89673:HSP90AA1
gene id: 89673:HSP90AA1
uniprot id: A0A6J2L1V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 90 family.
messages: Melanosome

89673:DEFB123
gene id: 89673:DEFB123
uniprot id: A0A6J2MMU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

89673:MTFR1L
gene id: 89673:MTFR1L
uniprot id: A0A6J2LIP1
uniprot id: A0A6J2LJZ1
uniprot id: A0A6J2LPC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

89673:MOV10
gene id: 89673:MOV10
uniprot id: A0A6J2KTV0
uniprot id: A0A7E6CYK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
messages: P-body

89673:POLL
gene id: 89673:POLL
uniprot id: A0A6J2LV59
uniprot id: A0A7E6DV24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
messages: Nucleus

89673:AP5M1
gene id: 89673:AP5M1
uniprot id: A0A6J2L498
uniprot id: A0A7E6CGW6
names: Subcellular Location Annotation
names: Subunit
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane
messages: Probably part of the adaptor protein complex 5 (AP-5) a tetramer composed of AP5B1, AP5M1, AP5S1 and AP5Z1.

89673:EOMES
gene id: 89673:EOMES
uniprot id: A0A6J2M678
uniprot id: A0A6J2M978
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

89673:LOC114504791
gene id: 89673:LOC114504791
uniprot id: A0A7E6CZC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

89673:CLP1
gene id: 89673:CLP1
uniprot id: A0A6J2LYJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Clp1 family. Clp1 subfamily.
messages: Component of the tRNA splicing endonuclease complex, composed of CLP1, TSEN2, TSEN15, TSEN34 and TSEN54. Component of pre-mRNA cleavage complex II (CF-II). Also associates with numerous components of the pre-mRNA cleavage complex I (CF-I/CFIm), including NUDT21, CPSF2, CPSF3, CPSF6 and CPSF7. Interacts with CSTF2 and SYMPK.
messages: Nucleus
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; this phosphorylation event is a prerequisite for the subsequent ligation of the two exon halves and the production of a mature tRNA. Component of the pre-mRNA cleavage complex II (CF-II), which seems to be required for mRNA 3'-end formation. Also phosphorylates the 5'-terminus of exogenously introduced short interfering RNAs (siRNAs), which is a necessary prerequisite for their incorporation into the RNA-induced silencing complex (RISC). However, endogenous siRNAs and microRNAs (miRNAs) that are produced by the cleavage of dsRNA precursors by DICER1 already contain a 5'-phosphate group, so this protein may be dispensible for normal RNA-mediated gene silencing.

89673:LOC114490734
gene id: 89673:LOC114490734
uniprot id: A0A6J2L2U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:AMER3
gene id: 89673:AMER3
uniprot id: A0A6J2MVZ1
names: Similarity
messages: Belongs to the Amer family.

89673:FFAR1
gene id: 89673:FFAR1
uniprot id: A0A6J2N1N4
uniprot id: A0A7E6CQF2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:LOC114509813
gene id: 89673:LOC114509813
uniprot id: A0A6J2N1N2
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit C family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.

89673:LOC114504872
gene id: 89673:LOC114504872
uniprot id: A0A7E6CZM7
names: Subcellular Location Annotation
messages: Membrane

89673:SLC6A11
gene id: 89673:SLC6A11
uniprot id: A0A6J2M9G8
uniprot id: A0A7E6E5U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

89673:CAPN1
gene id: 89673:CAPN1
uniprot id: A0A6J2LWX6
names: Similarity
messages: Belongs to the peptidase C2 family.

89673:LOC114490520
gene id: 89673:LOC114490520
uniprot id: A0A6J2KY39
uniprot id: A0A7E6D657
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

89673:LOC114499098
gene id: 89673:LOC114499098
uniprot id: A0A6J2LU35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114497297
gene id: 89673:LOC114497297
uniprot id: A0A6J2LP96
uniprot id: A0A7E6DV21
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

89673:LOC114497821
gene id: 89673:LOC114497821
uniprot id: A0A6J2LUI0
names: Similarity
messages: Belongs to the TAF9 family. CENP-S/MHF1 subfamily.

89673:GASK1A
gene id: 89673:GASK1A
uniprot id: A0A7E6E458
uniprot id: A0A7E6E5M9
names: Similarity
messages: Belongs to the GASK family.

89673:FXYD3
gene id: 89673:FXYD3
uniprot id: A0A7E6CLH0
names: Similarity
messages: Belongs to the FXYD family.

89673:KIZ
gene id: 89673:KIZ
uniprot id: A0A7E6CEK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kizuna family.
messages: Centrosomal protein required for establishing a robust mitotic centrosome architecture that can endure the forces that converge on the centrosomes during spindle formation. Required for stabilizing the expanded pericentriolar material around the centriole.
messages: centrosome
messages: cilium basal body

89673:ATP5MC1
gene id: 89673:ATP5MC1
uniprot id: A0A6J2MHU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

89673:SLC27A1
gene id: 89673:SLC27A1
uniprot id: A0A6J2M8N5
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

89673:ATP6V1E1
gene id: 89673:ATP6V1E1
uniprot id: A0A6J2MX40
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

89673:E2F8
gene id: 89673:E2F8
uniprot id: A0A6J2M0P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

89673:HDAC10
gene id: 89673:HDAC10
uniprot id: A0A7E6D8Q9
uniprot id: A0A7E6D8T6
uniprot id: A0A7E6D9L4
uniprot id: A0A7E6DBN3
names: Similarity
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.

89673:JPH2
gene id: 89673:JPH2
uniprot id: A0A6J2MLL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

89673:PSEN1
gene id: 89673:PSEN1
uniprot id: A0A6J2L3E2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Cytoplasmic granule
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: Synapse
messages: The PAL motif is required for normal active site conformation.
messages: axon
messages: neuron projection

89673:MAP7D1
gene id: 89673:MAP7D1
uniprot id: A0A6J2LI19
uniprot id: A0A6J2LKD9
uniprot id: A0A6J2LMZ3
uniprot id: A0A7E6DRW5
names: Similarity
messages: Belongs to the MAP7 family.

89673:LPAR5
gene id: 89673:LPAR5
uniprot id: A0A7E6D2P0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:HAT1
gene id: 89673:HAT1
uniprot id: A0A6J2LGT2
uniprot id: A0A6J2LK58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAT1 family.
messages: Catalytic subunit of the type B histone acetyltransferase (HAT) complex, composed of RBBP7 and HAT1. Interacts with histones H4 and H2A.
messages: Histone acetyltransferase that plays a role in different biological processes including cell cycle progression, glucose metabolism, histone production or DNA damage repair. Coordinates histone production and acetylation via H4 promoter binding. Acetylates histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, histone H2A at 'Lys-5' (H2AK5ac).

89673:IFNK
gene id: 89673:IFNK
uniprot id: A0A6J2MQV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

89673:PNPLA7
gene id: 89673:PNPLA7
uniprot id: A0A7E6DHA2
uniprot id: A0A7E6DHC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:NOS1
gene id: 89673:NOS1
uniprot id: A0A6J2N0G7
uniprot id: A0A7E6CRS9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOS family.
messages: Binds 1 FAD.
messages: Binds 1 FMN.
messages: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.
messages: dendritic spine
messages: sarcolemma

89673:DMD
gene id: 89673:DMD
uniprot id: A0A7E6CZS6
uniprot id: A0A7E6D020
uniprot id: A0A7E6D0P5
names: Subcellular Location Annotation
messages: cytoskeleton

89673:CHST11
gene id: 89673:CHST11
uniprot id: A0A6J2N7X3
uniprot id: A0A6J2NDF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

89673:LHX5
gene id: 89673:LHX5
uniprot id: A0A6J2MXF3
names: Subcellular Location Annotation
messages: Nucleus

89673:TCEA3
gene id: 89673:TCEA3
uniprot id: A0A7E6DQD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

89673:LOC114509904
gene id: 89673:LOC114509904
uniprot id: A0A6J2MVV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCRQ/QCR8 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 11 subunits. The complex is composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein UQCRFS1, 2 core protein subunits UQCRC1/QCR1 and UQCRC2/QCR2, and 6 low-molecular weight protein subunits UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and subunit 9, the cleavage product of Rieske protein UQCRFS1. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and cytochrome c oxidase (complex IV, CIV), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)). Interacts with UQCC6.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

89673:DGAT2
gene id: 89673:DGAT2
uniprot id: A0A6J2M4U4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:RPS6KB1
gene id: 89673:RPS6KB1
uniprot id: A0A6J2M7Y3
uniprot id: A0A6J2MB90
uniprot id: A0A6J2MBU1
uniprot id: A0A6J2MBU7
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

89673:DCTN5
gene id: 89673:DCTN5
uniprot id: A0A6J2LTC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunits 5/6 family. Dynactin subunit 5 subfamily.
messages: cytoskeleton

89673:GTF2A1
gene id: 89673:GTF2A1
uniprot id: A0A6J2L5C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus

89673:PRR15L
gene id: 89673:PRR15L
uniprot id: A0A6J2MEC5
names: Similarity
messages: Belongs to the PRR15 family.

89673:LOC114511294
gene id: 89673:LOC114511294
uniprot id: A0A7E6CNY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lambda interferon family.
messages: Secreted

89673:PPP6R1
gene id: 89673:PPP6R1
uniprot id: A0A6J2N2K9
uniprot id: A0A6J2N773
uniprot id: A0A7E6CNX7
uniprot id: A0A7E6CNZ5
names: Similarity
messages: Belongs to the SAPS family.

89673:POLR3GL
gene id: 89673:POLR3GL
uniprot id: A0A6J2KUG1
uniprot id: A0A6J2KYA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC7 RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

89673:GPKOW
gene id: 89673:GPKOW
uniprot id: A0A7E6D0V0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MOS2 family.
messages: Nucleus
messages: RNA-binding protein involved in pre-mRNA splicing.

89673:PDE6G
gene id: 89673:PDE6G
uniprot id: A0A6J2MGK0
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

89673:CPS1
gene id: 89673:CPS1
uniprot id: A0A6J2LE23
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:TAF4B
gene id: 89673:TAF4B
uniprot id: A0A6J2MKD3
uniprot id: A0A7E6CEB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Nucleus

89673:LOC114490380
gene id: 89673:LOC114490380
uniprot id: A0A6J2L3C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

89673:SLC37A2
gene id: 89673:SLC37A2
uniprot id: A0A6J2MUR5
uniprot id: A0A7E6CRT2
uniprot id: A0A7E6CUF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Inorganic phosphate and glucose-6-phosphate antiporter. May transport cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocate inorganic phosphate into the opposite direction. Independent of a lumenal glucose-6-phosphatase. May not play a role in homeostatic regulation of blood glucose levels.
messages: Membrane

89673:LOC114489679
gene id: 89673:LOC114489679
uniprot id: A0A7E6DXL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Lysosome membrane

89673:C6H2orf68
gene id: 89673:C6H2orf68
uniprot id: A0A6J2LTI4
names: Similarity
messages: Belongs to the UPF0561 family.

89673:ZHX1
gene id: 89673:ZHX1
uniprot id: A0A7E6E6S1
uniprot id: A0A7E6E8K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

89673:DIO2
gene id: 89673:DIO2
uniprot id: A0A6J2L668
names: Function
names: Similarity
messages: Belongs to the iodothyronine deiodinase family.
messages: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).

89673:TMEM190
gene id: 89673:TMEM190
uniprot id: A0A6J2MZK7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:YRDC
gene id: 89673:YRDC
uniprot id: A0A6J2LMG2
names: Similarity
messages: Belongs to the SUA5 family.

89673:TMEM167B
gene id: 89673:TMEM167B
uniprot id: A0A6J2KTJ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KISH family.
messages: Golgi apparatus membrane
messages: Involved in the early part of the secretory pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:ACOD1
gene id: 89673:ACOD1
uniprot id: A0A6J2MPP3
names: Similarity
messages: Belongs to the PrpD family.

89673:LOC114499179
gene id: 89673:LOC114499179
uniprot id: A0A6J2LUA5
names: Similarity
messages: Belongs to the CD225/Dispanin family.

89673:LOC114489773
gene id: 89673:LOC114489773
uniprot id: A0A6J2KW52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

89673:EFNB3
gene id: 89673:EFNB3
uniprot id: A0A6J2NDE1
uniprot id: A0A7E6ED44
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:CLSTN1
gene id: 89673:CLSTN1
uniprot id: A0A6J2LR83
uniprot id: A0A7E6DPR6
uniprot id: A0A7E6DPS5
uniprot id: A0A7E6DQE6
uniprot id: A0A7E6DQV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsyntenin family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Postsynaptic cell membrane

89673:LOC114502747
gene id: 89673:LOC114502747
uniprot id: A0A6J2MBJ7
names: Similarity
messages: Belongs to the cytochrome P450 family.

89673:HTR1E
gene id: 89673:HTR1E
uniprot id: A0A6J2LG22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:ATP1B4
gene id: 89673:ATP1B4
uniprot id: A0A6J2MHU0
uniprot id: A0A6J2MMA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

89673:SNX14
gene id: 89673:SNX14
uniprot id: A0A6J2L9L7
uniprot id: A0A6J2LA64
uniprot id: A0A6J2LBF2
uniprot id: A0A6J2LFA7
uniprot id: A0A7E6DMX7
uniprot id: A0A7E6DN95
names: Similarity
messages: Belongs to the sorting nexin family.

89673:LOC114506255
gene id: 89673:LOC114506255
uniprot id: A0A6J2MP04
names: Similarity
messages: Belongs to the copine family.

89673:LOC114503676
gene id: 89673:LOC114503676
uniprot id: A0A7E6E9B5
uniprot id: A0A7E6EAD1
uniprot id: A0A7E6EAY9
uniprot id: A0A7E6EBC3
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:PLA2G2D
gene id: 89673:PLA2G2D
uniprot id: A0A6J2LS12
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

89673:HMGCS1
gene id: 89673:HMGCS1
uniprot id: A0A6J2LZV2
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

89673:LOC114491362
gene id: 89673:LOC114491362
uniprot id: A0A6J2L4W5
names: Similarity
messages: Belongs to the SPATA31 family.

89673:ALKAL2
gene id: 89673:ALKAL2
uniprot id: A0A6J2M4T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALKAL family.
messages: Secreted

89673:SEC63
gene id: 89673:SEC63
uniprot id: A0A6J2L9E9
names: Subcellular Location Annotation
messages: Membrane

89673:FAM219B
gene id: 89673:FAM219B
uniprot id: A0A6J2L9D8
uniprot id: A0A7E6DX70
uniprot id: A0A7E6DY07
names: Similarity
messages: Belongs to the FAM219 family.

89673:ERH
gene id: 89673:ERH
uniprot id: A0A6J2NCY5
names: Function
names: Similarity
messages: Belongs to the E(R) family.
messages: May have a role in the cell cycle.

89673:BRINP2
gene id: 89673:BRINP2
uniprot id: A0A6J2N437
names: Similarity
messages: Belongs to the BRINP family.

89673:MRPL11
gene id: 89673:MRPL11
uniprot id: A0A6J2M1L3
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

89673:HS3ST6
gene id: 89673:HS3ST6
uniprot id: A0A6J2MMG4
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

89673:SOX21
gene id: 89673:SOX21
uniprot id: A0A7E6CJS8
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114499004
gene id: 89673:LOC114499004
uniprot id: A0A6J2LY67
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TMEM121B
gene id: 89673:TMEM121B
uniprot id: A0A6J2MY57
names: Similarity
messages: Belongs to the TMEM121 family.

89673:EBF4
gene id: 89673:EBF4
uniprot id: A0A6J2MK26
uniprot id: A0A7E6CEV6
uniprot id: A0A7E6CFI7
uniprot id: A0A7E6CH27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

89673:LOC114512992
gene id: 89673:LOC114512992
uniprot id: A0A6J2NCI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:DARS1
gene id: 89673:DARS1
uniprot id: A0A7E6DKP6
names: Function
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.

89673:DEFB113
gene id: 89673:DEFB113
uniprot id: A0A6J2LGA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

89673:MON1A
gene id: 89673:MON1A
uniprot id: A0A6J2M6K5
names: Function
names: Similarity
messages: Belongs to the MON1/SAND family.
messages: Plays an important role in membrane trafficking through the secretory apparatus.

89673:PCMTD1
gene id: 89673:PCMTD1
uniprot id: A0A6J2M149
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

89673:LOC114495412
gene id: 89673:LOC114495412
uniprot id: A0A7E6DH90
names: Similarity
messages: Belongs to the SUI1 family.

89673:PDE7B
gene id: 89673:PDE7B
uniprot id: A0A6J2LH29
uniprot id: A0A6J2LI12
uniprot id: A0A7E6DNT0
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

89673:COQ9
gene id: 89673:COQ9
uniprot id: A0A6J2KX63
uniprot id: A0A7E6CLK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ9 family.
messages: Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
messages: Mitochondrion

89673:CRTC3
gene id: 89673:CRTC3
uniprot id: A0A6J2KRF9
uniprot id: A0A6J2KS13
uniprot id: A0A7E6CMW6
uniprot id: A0A7E6CMW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TORC family.
messages: Cytoplasm
messages: Nucleus

89673:RAG1
gene id: 89673:RAG1
uniprot id: A0A6J2M5H8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAG1 family.
messages: Binds 1 divalent metal cation per subunit. Mg(2+) or Mn(2+).
messages: Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities. DNA cleavage occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the phosphodiester bond on the opposite strand in a direct transesterification reaction, thereby creating 4 DNA ends: 2 hairpin coding ends and 2 blunt, 5'-phosphorylated ends.
messages: Homodimer.
messages: Nucleus
messages: The NBD (nonamer binding) DNA-binding domain mediates the specific binding to the nonamer RSS motif by forming a tightly interwoven homodimer that binds and synapses 2 nonamer elements, with each NBD making contact with both DNA molecules. Each RSS is composed of well-conserved heptamer (consensus 5'-CACAGTG-3') and nonamer (consensus 5'-ACAAAAACC-3') sequences separated by a spacer of either 12 bp or 23 bp.

89673:DMGDH
gene id: 89673:DMGDH
uniprot id: A0A6J2MQW6
names: Similarity
messages: Belongs to the GcvT family.

89673:LOC114513341
gene id: 89673:LOC114513341
uniprot id: A0A6J2NE29
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

89673:MADD
gene id: 89673:MADD
uniprot id: A0A6J2LT88
uniprot id: A0A6J2LT95
uniprot id: A0A6J2LT99
uniprot id: A0A6J2LTA5
uniprot id: A0A6J2LTA9
uniprot id: A0A6J2LUG6
uniprot id: A0A6J2LUH1
uniprot id: A0A6J2LVD8
uniprot id: A0A6J2LVE3
uniprot id: A0A6J2LVF0
uniprot id: A0A6J2LYA5
uniprot id: A0A6J2LYB0
uniprot id: A0A6J2LYC4
uniprot id: A0A6J2LYS1
uniprot id: A0A6J2LYT2
uniprot id: A0A6J2LYU3
uniprot id: A0A7E6E114
uniprot id: A0A7E6E119
uniprot id: A0A7E6E124
uniprot id: A0A7E6E130
uniprot id: A0A7E6E137
uniprot id: A0A7E6E141
uniprot id: A0A7E6E145
uniprot id: A0A7E6E1J5
uniprot id: A0A7E6E1K2
uniprot id: A0A7E6E1K7
uniprot id: A0A7E6E1L2
uniprot id: A0A7E6E1L7
uniprot id: A0A7E6E1M3
uniprot id: A0A7E6E1R3
uniprot id: A0A7E6E1R9
uniprot id: A0A7E6E1S5
uniprot id: A0A7E6E1T0
uniprot id: A0A7E6E1T4
uniprot id: A0A7E6E1T7
uniprot id: A0A7E6E2F1
uniprot id: A0A7E6E2F6
uniprot id: A0A7E6E2G0
uniprot id: A0A7E6E2G2
uniprot id: A0A7E6E2G6
uniprot id: A0A7E6E2G8
uniprot id: A0A7E6E2H0
uniprot id: A0A7E6E2H4
uniprot id: A0A7E6E2H6
uniprot id: A0A7E6E2H9
uniprot id: A0A7E6E2I1
uniprot id: A0A7E6E2I6
uniprot id: A0A7E6E2J0
uniprot id: A0A7E6E2J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MADD family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

89673:DRAM2
gene id: 89673:DRAM2
uniprot id: A0A6J2KTL8
uniprot id: A0A7E6CWX3
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114511168
gene id: 89673:LOC114511168
uniprot id: A0A6J2MZN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

89673:FAM76A
gene id: 89673:FAM76A
uniprot id: A0A6J2LQG0
names: Similarity
messages: Belongs to the FAM76 family.

89673:RPF1
gene id: 89673:RPF1
uniprot id: A0A6J2LP59
names: Subcellular Location Annotation
messages: nucleolus

89673:LOC114495183
gene id: 89673:LOC114495183
uniprot id: A0A7E6DJJ7
names: Domain
names: Function
names: Similarity
messages: Belongs to the Xin family.
messages: Protects actin filaments from depolymerization.
messages: Xin repeats bind F-actin.

89673:SMIM8
gene id: 89673:SMIM8
uniprot id: A0A7E6DMG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM8 family.
messages: Membrane

89673:SFXN3
gene id: 89673:SFXN3
uniprot id: A0A6J2LTT7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

89673:LOC114494261
gene id: 89673:LOC114494261
uniprot id: A0A6J2LBC4
names: Similarity
messages: Belongs to the histone H2B family.

89673:LRRFIP1
gene id: 89673:LRRFIP1
uniprot id: A0A6J2LCG7
uniprot id: A0A6J2LEU3
uniprot id: A0A6J2LHF4
uniprot id: A0A7E6DHI7
uniprot id: A0A7E6DHJ7
uniprot id: A0A7E6DHN8
uniprot id: A0A7E6DHP2
uniprot id: A0A7E6DHP8
uniprot id: A0A7E6DHR1
uniprot id: A0A7E6DHR6
uniprot id: A0A7E6DHS2
uniprot id: A0A7E6DHT0
uniprot id: A0A7E6DHT5
uniprot id: A0A7E6DHU0
uniprot id: A0A7E6DHW0
uniprot id: A0A7E6DHW5
names: Similarity
messages: Belongs to the LRRFIP family.

89673:OPN1SW
gene id: 89673:OPN1SW
uniprot id: A0A6J2MPC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: Photoreceptor inner segment
messages: photoreceptor outer segment

89673:CNOT7
gene id: 89673:CNOT7
uniprot id: A0A6J2MW94
uniprot id: A0A7E6CKY4
uniprot id: A0A7E6CL16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

89673:TMEM225B
gene id: 89673:TMEM225B
uniprot id: A0A6J2L4S8
uniprot id: A0A6J2L6F9
names: Subcellular Location Annotation
messages: Membrane

89673:CLDN23
gene id: 89673:CLDN23
uniprot id: A0A6J2MR74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

89673:LOC114513575
gene id: 89673:LOC114513575
uniprot id: A0A6J2N879
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114492628
gene id: 89673:LOC114492628
uniprot id: A0A6J2LB98
uniprot id: A0A7E6EBU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DUOXA family.
messages: Membrane

89673:OLFML2B
gene id: 89673:OLFML2B
uniprot id: A0A7E6CVP1
uniprot id: A0A7E6CYG0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:TMEM216
gene id: 89673:TMEM216
uniprot id: A0A6J2LTQ8
uniprot id: A0A6J2LWQ1
names: Subcellular Location Annotation
messages: Membrane

89673:RRH
gene id: 89673:RRH
uniprot id: A0A6J2L7W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

89673:RHCE
gene id: 89673:RHCE
uniprot id: A0A6J2LTB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

89673:SLC15A3
gene id: 89673:SLC15A3
uniprot id: A0A6J2M1Y6
names: Similarity
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.

89673:SLC30A5
gene id: 89673:SLC30A5
uniprot id: A0A6J2L7S3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Functions as a zinc transporter.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: trans-Golgi network membrane

89673:ADH6
gene id: 89673:ADH6
uniprot id: A0A6J2L3P3
uniprot id: A0A7E6DSZ3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

89673:DCK
gene id: 89673:DCK
uniprot id: A0A6J2L5Y8
names: Similarity
messages: Belongs to the DCK/DGK family.

89673:NAPG
gene id: 89673:NAPG
uniprot id: A0A6J2MQE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

89673:CDK5R2
gene id: 89673:CDK5R2
uniprot id: A0A6J2LG53
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin-dependent kinase 5 activator family.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit and a regulatory subunit.
messages: Membrane

89673:TERF2
gene id: 89673:TERF2
uniprot id: A0A6J2NDH4
uniprot id: A0A6J2NF41
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.
messages: Homodimer.
messages: Nucleus
messages: telomere

89673:LOC114501716
gene id: 89673:LOC114501716
uniprot id: A0A6J2M7J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYT1 family.
messages: Nucleus

89673:SLC10A5
gene id: 89673:SLC10A5
uniprot id: A0A6J2M5B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

89673:INKA1
gene id: 89673:INKA1
uniprot id: A0A6J2M135
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INKA family.
messages: Nucleus

89673:ENTR1
gene id: 89673:ENTR1
uniprot id: A0A6J2M6L1
uniprot id: A0A7E6DGX2
names: Similarity
messages: Belongs to the ENTR1 family.

89673:LOC118498385
gene id: 89673:LOC118498385
uniprot id: A0A7E6CZT0
names: Similarity
messages: Belongs to the SSX family.

89673:LOC114488537
gene id: 89673:LOC114488537
uniprot id: A0A6J2KRH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the neugrin family.
messages: Forms a regulatory protein-RNA complex, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mt-rRNA. Interacts with 16S mt-rRNA; this interaction is direct.
messages: Mitochondrion membrane
messages: Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.

89673:ABCC3
gene id: 89673:ABCC3
uniprot id: A0A6J2MF19
uniprot id: A0A7E6EE75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

89673:DOCK4
gene id: 89673:DOCK4
uniprot id: A0A6J2MNW2
uniprot id: A0A7E6CH67
uniprot id: A0A7E6CJ68
names: Similarity
messages: Belongs to the DOCK family.

89673:UNC5CL
gene id: 89673:UNC5CL
uniprot id: A0A6J2LG99
names: Similarity
messages: Belongs to the unc-5 family.

89673:SPDYA
gene id: 89673:SPDYA
uniprot id: A0A6J2M2Q6
names: Similarity
messages: Belongs to the Speedy/Ringo family.

89673:PIGM
gene id: 89673:PIGM
uniprot id: A0A6J2N251
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGM family.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly.
messages: Membrane

89673:STOM
gene id: 89673:STOM
uniprot id: A0A6J2LAF8
names: Similarity
messages: Belongs to the band 7/mec-2 family.

89673:UFD1
gene id: 89673:UFD1
uniprot id: A0A6J2N225
uniprot id: A0A7E6CUJ9
names: Similarity
messages: Belongs to the UFD1 family.

89673:CTNS
gene id: 89673:CTNS
uniprot id: A0A7E6ECP3
uniprot id: A0A7E6EDN2
uniprot id: A0A7E6EDV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cystinosin family.
messages: Membrane

89673:OLAH
gene id: 89673:OLAH
uniprot id: A0A7E6DLX7
names: Similarity
messages: Belongs to the thioesterase family.

89673:JAGN1
gene id: 89673:JAGN1
uniprot id: A0A6J2M6Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the jagunal family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:ARVCF
gene id: 89673:ARVCF
uniprot id: A0A6J2MT27
uniprot id: A0A6J2MUN8
uniprot id: A0A6J2MUQ3
uniprot id: A0A6J2MZA2
uniprot id: A0A6J2MZA5
uniprot id: A0A6J2MZS2
uniprot id: A0A7E6CSK1
uniprot id: A0A7E6CT08
uniprot id: A0A7E6CT94
names: Similarity
messages: Belongs to the beta-catenin family.

89673:LOC114498086
gene id: 89673:LOC114498086
uniprot id: A0A7E6DPR1
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.

89673:SEMA3B
gene id: 89673:SEMA3B
uniprot id: A0A6J2M2E4
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:SSH2
gene id: 89673:SSH2
uniprot id: A0A6J2MDX4
uniprot id: A0A6J2MHT1
uniprot id: A0A7E6ECT6
uniprot id: A0A7E6ECZ8
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

89673:LOC114500481
gene id: 89673:LOC114500481
uniprot id: A0A7E6E2N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:IL17D
gene id: 89673:IL17D
uniprot id: A0A7E6CZB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

89673:CACNA2D1
gene id: 89673:CACNA2D1
uniprot id: A0A6J2MLW7
uniprot id: A0A6J2MLX2
uniprot id: A0A6J2MNQ3
uniprot id: A0A6J2MNU0
uniprot id: A0A6J2MT43
uniprot id: A0A6J2MT47
uniprot id: A0A7E6CHY5
uniprot id: A0A7E6CI17
uniprot id: A0A7E6CI80
uniprot id: A0A7E6CIC6
uniprot id: A0A7E6CK05
uniprot id: A0A7E6CK12
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

89673:LOC114501650
gene id: 89673:LOC114501650
uniprot id: A0A6J2M9E5
uniprot id: A0A7E6DDZ7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Inflammasome

89673:RNF5
gene id: 89673:RNF5
uniprot id: A0A6J2LB34
uniprot id: A0A6J2LFV7
names: Domain
names: Function
names: Subcellular Location Annotation
messages: E3 ubiquitin-protein ligase.
messages: Endoplasmic reticulum membrane
messages: Mitochondrion membrane
messages: The RING-type zinc finger domain is responsible for E3 ligase activity.

89673:ANAPC13
gene id: 89673:ANAPC13
uniprot id: A0A6J2M7E1
names: Function
names: Similarity
messages: Belongs to the APC13 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

89673:SUPT6H
gene id: 89673:SUPT6H
uniprot id: A0A6J2MAZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT6 family.
messages: Nucleus
messages: Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII).

89673:MTHFD1
gene id: 89673:MTHFD1
uniprot id: A0A6J2L3C2
uniprot id: A0A6J2L6M2
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

89673:ALG12
gene id: 89673:ALG12
uniprot id: A0A6J2NEN1
uniprot id: A0A7E6D8R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:TWSG1
gene id: 89673:TWSG1
uniprot id: A0A6J2MQ88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the twisted gastrulation protein family.
messages: Secreted

89673:PDX1
gene id: 89673:PDX1
uniprot id: A0A6J2L0B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

89673:CHSY1
gene id: 89673:CHSY1
uniprot id: A0A7E6CPF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

89673:LOC114508230
gene id: 89673:LOC114508230
uniprot id: A0A6J2MW23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

89673:LOC114498456
gene id: 89673:LOC114498456
uniprot id: A0A6J2LT40
names: Similarity
messages: Belongs to the MS4A family.

89673:PTX4
gene id: 89673:PTX4
uniprot id: A0A6J2MSZ2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:RDH10
gene id: 89673:RDH10
uniprot id: A0A6J2M7Q8
uniprot id: A0A7E6E6A5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

89673:STAB1
gene id: 89673:STAB1
uniprot id: A0A6J2M2Q7
uniprot id: A0A7E6E5A5
uniprot id: A0A7E6E6T8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:RPL9
gene id: 89673:RPL9
uniprot id: A0A6J2LBT4
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

89673:LOC114500278
gene id: 89673:LOC114500278
uniprot id: A0A6J2M3D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114500436
gene id: 89673:LOC114500436
uniprot id: A0A6J2M024
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:NCBP3
gene id: 89673:NCBP3
uniprot id: A0A6J2NE06
uniprot id: A0A7E6EDM1
names: Similarity
messages: Belongs to the NCBP3 family.

89673:LOC114497271
gene id: 89673:LOC114497271
uniprot id: A0A6J2LS63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVBP family.
messages: Secreted
messages: cytoskeleton

89673:LOC114500377
gene id: 89673:LOC114500377
uniprot id: A0A6J2M3P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:MINDY2
gene id: 89673:MINDY2
uniprot id: A0A6J2L1V8
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM63 subfamily.
messages: Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins. Has exodeubiquitinase activity and has a preference for long polyubiquitin chains. May play a regulatory role at the level of protein turnover.

89673:AP4S1
gene id: 89673:AP4S1
uniprot id: A0A6J2LAD4
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

89673:GTF2E2
gene id: 89673:GTF2E2
uniprot id: A0A6J2MY50
uniprot id: A0A7E6CKY3
uniprot id: A0A7E6CN00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFIIE beta subunit family.
messages: Nucleus
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
messages: Tetramer of two alpha and two beta chains.

89673:SLC16A1
gene id: 89673:SLC16A1
uniprot id: A0A6J2KV87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

89673:ACADSB
gene id: 89673:ACADSB
uniprot id: A0A6J2LRT4
uniprot id: A0A7E6DVX7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

89673:LOC114502881
gene id: 89673:LOC114502881
uniprot id: A0A6J2M8S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM98 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: extracellular exosome

89673:ERO1B
gene id: 89673:ERO1B
uniprot id: A0A6J2NB51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane

89673:EDNRB
gene id: 89673:EDNRB
uniprot id: A0A6J2MWS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:EXT2
gene id: 89673:EXT2
uniprot id: A0A6J2LYU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:PUS3
gene id: 89673:PUS3
uniprot id: A0A6J2MWJ2
uniprot id: A0A7E6CV69
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

89673:INO80
gene id: 89673:INO80
uniprot id: A0A7E6D4I1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Component of the INO80 chromatin-remodeling complex.
messages: Nucleus
messages: The DBINO region is involved in binding to DNA.

89673:LOC114511039
gene id: 89673:LOC114511039
uniprot id: A0A6J2MZ33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOSIP family.
messages: Cytoplasm
messages: Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity.
messages: Nucleus

89673:LOC114504039
gene id: 89673:LOC114504039
uniprot id: A0A6J2MGR8
uniprot id: A0A7E6EEL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HOP2 family.
messages: Nucleus

89673:PSMA5
gene id: 89673:PSMA5
uniprot id: A0A6J2L032
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

89673:TAS2R9
gene id: 89673:TAS2R9
uniprot id: A0A6J2NB17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

89673:ADM
gene id: 89673:ADM
uniprot id: A0A6J2M2G1
uniprot id: A0A7E6E1G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adrenomedullin family.
messages: Secreted

89673:TMEM30B
gene id: 89673:TMEM30B
uniprot id: A0A7E6CIA7
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

89673:TSEN54
gene id: 89673:TSEN54
uniprot id: A0A6J2M8T8
uniprot id: A0A7E6EFD1
names: Similarity
messages: Belongs to the SEN54 family.

89673:ATP2B1
gene id: 89673:ATP2B1
uniprot id: A0A6J2N4H2
uniprot id: A0A7E6D5E2
uniprot id: A0A7E6D5I2
uniprot id: A0A7E6D618
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:LOC114494272
gene id: 89673:LOC114494272
uniprot id: A0A6J2LBD5
names: Similarity
messages: Belongs to the peptidase S9A family.

89673:LANCL1
gene id: 89673:LANCL1
uniprot id: A0A6J2LGN9
names: Similarity
messages: Belongs to the LanC-like protein family.

89673:PSMD5
gene id: 89673:PSMD5
uniprot id: A0A6J2MFW4
names: Similarity
messages: Belongs to the proteasome subunit S5B/HSM3 family.

89673:PRAME
gene id: 89673:PRAME
uniprot id: A0A6J2N3Y4
names: Similarity
messages: Belongs to the PRAME family.

89673:HIRIP3
gene id: 89673:HIRIP3
uniprot id: A0A6J2N372
uniprot id: A0A7E6DD26
names: Subcellular Location Annotation
messages: Nucleus

89673:HGF
gene id: 89673:HGF
uniprot id: A0A6J2MMV3
uniprot id: A0A6J2MPS4
uniprot id: A0A7E6CI85
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Dimer of an alpha chain and a beta chain linked by a disulfide bond.
messages: Dimer of an alpha chain and a beta chain linked by a disulfide bond. Interacts with SRPX2; the interaction increases HGF mitogenic activity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization.

89673:IMPDH1
gene id: 89673:IMPDH1
uniprot id: A0A6J2MQ52
uniprot id: A0A6J2MUJ4
uniprot id: A0A6J2MUT0
uniprot id: A0A7E6CIH0
uniprot id: A0A7E6CIW4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.
messages: Nucleus

89673:RSPO4
gene id: 89673:RSPO4
uniprot id: A0A6J2MNB0
names: Similarity
messages: Belongs to the R-spondin family.

89673:LOC114511295
gene id: 89673:LOC114511295
uniprot id: A0A6J2N6C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hepcidin family.
messages: Secreted

89673:CD27
gene id: 89673:CD27
uniprot id: A0A6J2NET6
uniprot id: A0A7E6D1V0
uniprot id: A0A7E6D2P4
uniprot id: A0A7E6D4M7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114505595
gene id: 89673:LOC114505595
uniprot id: A0A6J2MMU3
names: Similarity
messages: Belongs to the SPT20 family.

89673:EIF2B5
gene id: 89673:EIF2B5
uniprot id: A0A6J2L3P7
names: Similarity
messages: Belongs to the eIF-2B gamma/epsilon subunits family.

89673:FGF4
gene id: 89673:FGF4
uniprot id: A0A6J2M575
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

89673:LOC114510571
gene id: 89673:LOC114510571
uniprot id: A0A7E6CQX3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:TPD52L3
gene id: 89673:TPD52L3
uniprot id: A0A7E6D9I5
names: Similarity
messages: Belongs to the TPD52 family.

89673:RRAGC
gene id: 89673:RRAGC
uniprot id: A0A6J2LIP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

89673:CCL24
gene id: 89673:CCL24
uniprot id: A0A6J2LXX6
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.

89673:CRYGN
gene id: 89673:CRYGN
uniprot id: A0A6J2MN32
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

89673:STPG4
gene id: 89673:STPG4
uniprot id: A0A6J2M280
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

89673:NECTIN3
gene id: 89673:NECTIN3
uniprot id: A0A6J2KXK0
uniprot id: A0A6J2KXL5
uniprot id: A0A7E6D3Z9
uniprot id: A0A7E6D430
uniprot id: A0A7E6D4J5
names: Similarity
messages: Belongs to the nectin family.

89673:BLOC1S3
gene id: 89673:BLOC1S3
uniprot id: A0A7E6CPR8
names: Similarity
messages: Belongs to the BLOC1S3 family.

89673:PRPF38B
gene id: 89673:PRPF38B
uniprot id: A0A6J2KYL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP38 family.
messages: May be required for pre-mRNA splicing.
messages: Nucleus

89673:MB
gene id: 89673:MB
uniprot id: A0A6J2N7N6
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

89673:AFMID
gene id: 89673:AFMID
uniprot id: A0A6J2MEB0
uniprot id: A0A7E6EGK8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynurenine formamidase family.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.
messages: Homodimer.
messages: Nucleus
messages: The main chain amide nitrogen atoms of the second glycine and its adjacent residue in the HGGXW motif define the oxyanion hole, and stabilize the oxyanion that forms during the nucleophilic attack by the catalytic serine during substrate cleavage.
messages: cytosol

89673:DOT1L
gene id: 89673:DOT1L
uniprot id: A0A6J2M8B1
uniprot id: A0A6J2MB39
uniprot id: A0A7E6E8T2
uniprot id: A0A7E6E9M0
uniprot id: A0A7E6E9T1
uniprot id: A0A7E6E9T6
uniprot id: A0A7E6EAE8
uniprot id: A0A7E6EAT7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.
messages: Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.
messages: Histone methyltransferase. Methylates 'Lys-79' of histone H3.
messages: In contrast to other lysine histone methyltransferases, it does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones.
messages: Nucleus

89673:PHLDA1
gene id: 89673:PHLDA1
uniprot id: A0A6J2L1L4
uniprot id: A0A7E6D5L0
names: Subcellular Location Annotation
messages: Cytoplasm

89673:GNPAT
gene id: 89673:GNPAT
uniprot id: A0A6J2N561
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Peroxisome membrane

89673:ITGB2
gene id: 89673:ITGB2
uniprot id: A0A6J2KYN0
uniprot id: A0A7E6D544
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane
messages: Membrane raft

89673:FZR1
gene id: 89673:FZR1
uniprot id: A0A6J2M4R9
uniprot id: A0A6J2MAD8
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

89673:BVES
gene id: 89673:BVES
uniprot id: A0A6J2LED0
names: Similarity
messages: Belongs to the popeye family.

89673:LOC114488437
gene id: 89673:LOC114488437
uniprot id: A0A6J2KRU0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:ESR1
gene id: 89673:ESR1
uniprot id: A0A6J2LFK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Binds DNA as a homodimer.
messages: Membrane
messages: Nucleus
messages: The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.

89673:RCL1
gene id: 89673:RCL1
uniprot id: A0A6J2MQS1
uniprot id: A0A7E6DEU9
uniprot id: A0A7E6DEZ5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
messages: Part of the small subunit (SSU) processome, composed of more than 70 proteins and the RNA chaperone small nucleolar RNA (snoRNA) U3.
messages: nucleolus

89673:FAM53C
gene id: 89673:FAM53C
uniprot id: A0A6J2MZ16
names: Similarity
messages: Belongs to the FAM53 family.

89673:GNGT2
gene id: 89673:GNGT2
uniprot id: A0A6J2ME49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

89673:UEVLD
gene id: 89673:UEVLD
uniprot id: A0A7E6E0U5
uniprot id: A0A7E6E1S8
names: Similarity
messages: Belongs to the LDH/MDH superfamily.

89673:EML2
gene id: 89673:EML2
uniprot id: A0A6J2N016
uniprot id: A0A6J2N1R2
uniprot id: A0A6J2N770
uniprot id: A0A7E6CPU4
uniprot id: A0A7E6CPY9
names: Similarity
messages: Belongs to the WD repeat EMAP family.

89673:LIMS1
gene id: 89673:LIMS1
uniprot id: A0A6J2LNM1
uniprot id: A0A7E6DTI6
uniprot id: A0A7E6DTN3
uniprot id: A0A7E6DU56
uniprot id: A0A7E6DUS4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Adapter protein in a cytoplasmic complex linking beta-integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors.
messages: Cell membrane
messages: Part of the heterotrimeric IPP complex composed of integrin-linked kinase (ILK), LIMS1 or LIMS2, and PARVA.
messages: focal adhesion

89673:LOC114505677
gene id: 89673:LOC114505677
uniprot id: A0A7E6D0J1
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

89673:SLC19A1
gene id: 89673:SLC19A1
uniprot id: A0A6J2KXS8
uniprot id: A0A6J2KZH9
uniprot id: A0A7E6D2C1
uniprot id: A0A7E6D553
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

89673:METAP1
gene id: 89673:METAP1
uniprot id: A0A6J2L8J0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

89673:LOC114500508
gene id: 89673:LOC114500508
uniprot id: A0A6J2M176
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CHD5
gene id: 89673:CHD5
uniprot id: A0A6J2LMQ4
uniprot id: A0A7E6DPM1
uniprot id: A0A7E6DQB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

89673:HTR7
gene id: 89673:HTR7
uniprot id: A0A6J2LQ51
uniprot id: A0A6J2LRC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:SLC10A4
gene id: 89673:SLC10A4
uniprot id: A0A6J2L7A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

89673:MCRIP1
gene id: 89673:MCRIP1
uniprot id: A0A6J2MCJ1
uniprot id: A0A7E6EGR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCRIP family.
messages: Nucleus
messages: Stress granule

89673:REV3L
gene id: 89673:REV3L
uniprot id: A0A6J2LCN7
uniprot id: A0A7E6DMT3
uniprot id: A0A7E6DNA9
uniprot id: A0A7E6DND8
uniprot id: A0A7E6DNQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

89673:LOC114489883
gene id: 89673:LOC114489883
uniprot id: A0A6J2KVU6
uniprot id: A0A6J2L1Q5
uniprot id: A0A7E6D1G7
uniprot id: A0A7E6D474
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Component of the 43S pre-initiation complex (43S PIC), which binds to the mRNA cap-proximal region, scans mRNA 5'-untranslated region, and locates the initiation codon. This protein enhances formation of the cap-proximal complex. Together with EIF1, facilitates scanning, start codon recognition, promotion of the assembly of 48S complex at the initiation codon (43S PIC becomes 48S PIC after the start codon is reached), and dissociation of aberrant complexes. After start codon location, together with EIF5B orients the initiator methionine-tRNA in a conformation that allows 60S ribosomal subunit joining to form the 80S initiation complex. Is released after 80S initiation complex formation, just after GTP hydrolysis by EIF5B, and before release of EIF5B. Its globular part is located in the A site of the 40S ribosomal subunit. Its interaction with EIF5 during scanning contribute to the maintenance of EIF1 within the open 43S PIC. In contrast to yeast orthologs, does not bind EIF1.

89673:LOC114501033
gene id: 89673:LOC114501033
uniprot id: A0A6J2M2S1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SLC8A3
gene id: 89673:SLC8A3
uniprot id: A0A6J2L8N5
uniprot id: A0A6J2L8P0
uniprot id: A0A6J2LAD2
uniprot id: A0A6J2LEB2
uniprot id: A0A7E6CKF6
uniprot id: A0A7E6CKG0
uniprot id: A0A7E6CKJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

89673:NEIL3
gene id: 89673:NEIL3
uniprot id: A0A6J2MT39
names: Similarity
messages: Belongs to the FPG family.

89673:ACVR2B
gene id: 89673:ACVR2B
uniprot id: A0A6J2M3X9
uniprot id: A0A7E6E4U9
uniprot id: A0A7E6E4Z1
uniprot id: A0A7E6E5S8
uniprot id: A0A7E6E5Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

89673:ARMC1
gene id: 89673:ARMC1
uniprot id: A0A6J2NCB6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.
messages: Membrane
messages: Mitochondrion outer membrane

89673:ATP5F1C
gene id: 89673:ATP5F1C
uniprot id: A0A6J2L4D2
uniprot id: A0A6J2L518
uniprot id: A0A6J2L6N9
uniprot id: A0A6J2LAE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

89673:LOC114498967
gene id: 89673:LOC114498967
uniprot id: A0A7E6E3E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL18 family.
messages: Rough endoplasmic reticulum

89673:LOC114500016
gene id: 89673:LOC114500016
uniprot id: A0A6J2LXD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

89673:ARHGEF11
gene id: 89673:ARHGEF11
uniprot id: A0A6J2KUK0
uniprot id: A0A6J2KV42
uniprot id: A0A7E6CWS8
uniprot id: A0A7E6CWT3
uniprot id: A0A7E6CWU1
uniprot id: A0A7E6CWX0
uniprot id: A0A7E6CWX4
uniprot id: A0A7E6CWX8
uniprot id: A0A7E6CXA5
uniprot id: A0A7E6CXB0
uniprot id: A0A7E6CXB6
uniprot id: A0A7E6CXN1
uniprot id: A0A7E6CXN5
uniprot id: A0A7E6CXP1
uniprot id: A0A7E6CZG3
uniprot id: A0A7E6CZG8
uniprot id: A0A7E6CZH1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane

89673:HK1
gene id: 89673:HK1
uniprot id: A0A6J2LIS2
uniprot id: A0A7E6DU69
uniprot id: A0A7E6DV45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hexokinase family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: cytosol

89673:LOC114503940
gene id: 89673:LOC114503940
uniprot id: A0A7E6EE24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SERINC3
gene id: 89673:SERINC3
uniprot id: A0A6J2MKF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

89673:AEBP1
gene id: 89673:AEBP1
uniprot id: A0A6J2KX53
uniprot id: A0A7E6CH19
uniprot id: A0A7E6CH84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

89673:IKBKE
gene id: 89673:IKBKE
uniprot id: A0A6J2N4S4
names: Subcellular Location Annotation
messages: Cytoplasm

89673:LOC114498667
gene id: 89673:LOC114498667
uniprot id: A0A7E6DY17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

89673:LOC114509085
gene id: 89673:LOC114509085
uniprot id: A0A6J2MYR7
uniprot id: A0A7E6DH63
names: Similarity
messages: Belongs to the ficolin lectin family.

89673:LOC114513835
gene id: 89673:LOC114513835
uniprot id: A0A6J2NAS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

89673:LOC114490006
gene id: 89673:LOC114490006
uniprot id: A0A6J2KYJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

89673:MINAR2
gene id: 89673:MINAR2
uniprot id: A0A6J2MU05
names: Similarity
messages: Belongs to the MINAR family.

89673:PARP16
gene id: 89673:PARP16
uniprot id: A0A6J2L8M5
uniprot id: A0A6J2LDV0
uniprot id: A0A7E6CG26
names: Similarity
messages: Belongs to the ARTD/PARP family.

89673:CENPX
gene id: 89673:CENPX
uniprot id: A0A6J2MHR1
uniprot id: A0A7E6EF11
names: Similarity
messages: Belongs to the CENP-X/MHF2 family.

89673:HACD1
gene id: 89673:HACD1
uniprot id: A0A6J2L8P2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:IQSEC1
gene id: 89673:IQSEC1
uniprot id: A0A6J2KYU9
uniprot id: A0A6J2KZE9
uniprot id: A0A6J2KZF4
uniprot id: A0A6J2L127
uniprot id: A0A6J2L129
uniprot id: A0A6J2L2U9
uniprot id: A0A6J2L4I2
uniprot id: A0A6J2L4I7
uniprot id: A0A7E6D4J2
uniprot id: A0A7E6D4N0
uniprot id: A0A7E6D4Q9
uniprot id: A0A7E6D585
uniprot id: A0A7E6D588
uniprot id: A0A7E6D7D3
names: Similarity
messages: Belongs to the BRAG family.

89673:POU2F2
gene id: 89673:POU2F2
uniprot id: A0A6J2N165
uniprot id: A0A6J2N7G9
uniprot id: A0A7E6CP37
uniprot id: A0A7E6CP49
uniprot id: A0A7E6CPB3
uniprot id: A0A7E6CPC8
uniprot id: A0A7E6CRJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-2 subfamily.
messages: Nucleus
messages: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR.

89673:LOC114497505
gene id: 89673:LOC114497505
uniprot id: A0A6J2LT47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Mitochondrion

89673:LOC114512060
gene id: 89673:LOC114512060
uniprot id: A0A6J2N4I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

89673:LOC114513382
gene id: 89673:LOC114513382
uniprot id: A0A6J2NEV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114491360
gene id: 89673:LOC114491360
uniprot id: A0A7E6E2W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KISH family.
messages: Golgi apparatus membrane
messages: Involved in the early part of the secretory pathway.
messages: Membrane

89673:LOC114499960
gene id: 89673:LOC114499960
uniprot id: A0A6J2M272
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.

89673:LOC114499681
gene id: 89673:LOC114499681
uniprot id: A0A6J2M0V3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:SLC7A1
gene id: 89673:SLC7A1
uniprot id: A0A6J2KYM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

89673:GPHN
gene id: 89673:GPHN
uniprot id: A0A6J2L995
uniprot id: A0A6J2LDD0
uniprot id: A0A6J2LEH2
uniprot id: A0A7E6CJA1
uniprot id: A0A7E6CJF8
uniprot id: A0A7E6CLA8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
messages: In the C-terminal section; belongs to the MoeA family.
messages: In the N-terminal section; belongs to the MoaB/Mog family.

89673:RPL26L1
gene id: 89673:RPL26L1
uniprot id: A0A6J2N103
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

89673:TAP1
gene id: 89673:TAP1
uniprot id: A0A6J2LEP3
uniprot id: A0A7E6DLB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCB family. MHC peptide exporter (TC 3.A.1.209) subfamily.
messages: Membrane

89673:NKRF
gene id: 89673:NKRF
uniprot id: A0A6J2MJ83
names: Similarity
messages: Belongs to the CARF family.

89673:CKMT2
gene id: 89673:CKMT2
uniprot id: A0A6J2MFD9
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

89673:ABT1
gene id: 89673:ABT1
uniprot id: A0A6J2L128
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF2/ABP1 family.
messages: nucleolus

89673:SKOR1
gene id: 89673:SKOR1
uniprot id: A0A6J2L602
names: Similarity
messages: Belongs to the SKI family.

89673:GRIK1
gene id: 89673:GRIK1
uniprot id: A0A6J2KYP9
uniprot id: A0A6J2L2C3
uniprot id: A0A7E6D2R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

89673:SOD3
gene id: 89673:SOD3
uniprot id: A0A6J2LBN4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

89673:RAD18
gene id: 89673:RAD18
uniprot id: A0A6J2M9F2
uniprot id: A0A7E6E583
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD18 family.
messages: Nucleus

89673:SCNM1
gene id: 89673:SCNM1
uniprot id: A0A6J2KSY8
uniprot id: A0A6J2KWS5
uniprot id: A0A7E6CXF1
names: Subcellular Location Annotation
messages: Nucleus speckle
messages: nucleoplasm

89673:LRWD1
gene id: 89673:LRWD1
uniprot id: A0A6J2MFD6
uniprot id: A0A7E6DDG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRWD1 family.
messages: centrosome
messages: kinetochore
messages: telomere

89673:RPRD1B
gene id: 89673:RPRD1B
uniprot id: A0A6J2MK85
uniprot id: A0A7E6CFF4
uniprot id: A0A7E6CHK8
names: Function
names: Similarity
names: Subunit
messages: Associates with the RNA polymerase II complex.
messages: Belongs to the UPF0400 (RTT103) family.
messages: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD.

89673:LOC114490854
gene id: 89673:LOC114490854
uniprot id: A0A7E6DEG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

89673:USH2A
gene id: 89673:USH2A
uniprot id: A0A6J2N5J9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:VPS26A
gene id: 89673:VPS26A
uniprot id: A0A6J2LIC4
uniprot id: A0A6J2LJN7
uniprot id: A0A6J2LNB8
names: Similarity
messages: Belongs to the VPS26 family.

89673:DYNLL1
gene id: 89673:DYNLL1
uniprot id: A0A6J2MU72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

89673:MPHOSPH10
gene id: 89673:MPHOSPH10
uniprot id: A0A6J2KTZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPP10 family.
messages: Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.
messages: nucleolus

89673:LOC114494333
gene id: 89673:LOC114494333
uniprot id: A0A6J2LGG9
uniprot id: A0A7E6DIA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STK11IP family.
messages: Cytoplasm

89673:LOC114496860
gene id: 89673:LOC114496860
uniprot id: A0A7E6DCB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:LRRC8D
gene id: 89673:LRRC8D
uniprot id: A0A6J2LVG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

89673:NDUFB2
gene id: 89673:NDUFB2
uniprot id: A0A6J2MVD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB2 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

89673:PATZ1
gene id: 89673:PATZ1
uniprot id: A0A6J2MVC5
uniprot id: A0A6J2MWZ7
uniprot id: A0A6J2MX12
uniprot id: A0A6J2N1J3
uniprot id: A0A6J2N280
uniprot id: A0A7E6CSS9
names: Subcellular Location Annotation
messages: Nucleus

89673:GABRA2
gene id: 89673:GABRA2
uniprot id: A0A6J2L9R8
uniprot id: A0A6J2LDR1
uniprot id: A0A7E6D9X5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA2 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: dendrite

89673:RPS8
gene id: 89673:RPS8
uniprot id: A0A6J2LTI6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS8 family.

89673:DPF1
gene id: 89673:DPF1
uniprot id: A0A6J2N0F3
uniprot id: A0A6J2N0H9
uniprot id: A0A6J2N5W0
uniprot id: A0A7E6CM61
uniprot id: A0A7E6CM90
uniprot id: A0A7E6CPF5
names: Similarity
messages: Belongs to the requiem/DPF family.

89673:MNS1
gene id: 89673:MNS1
uniprot id: A0A6J2L8D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MNS1 family.
messages: Nucleus
messages: cilium axoneme
messages: flagellum axoneme

89673:TM9SF3
gene id: 89673:TM9SF3
uniprot id: A0A6J2LP69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

89673:UBE2D1
gene id: 89673:UBE2D1
uniprot id: A0A6J2LP86
uniprot id: A0A7E6DUI8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

89673:RPS6KB2
gene id: 89673:RPS6KB2
uniprot id: A0A6J2LUH2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

89673:NDUFS6
gene id: 89673:NDUFS6
uniprot id: A0A6J2MBA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS6 subunit family.
messages: Mitochondrion inner membrane

89673:SARDH
gene id: 89673:SARDH
uniprot id: A0A6J2MBD4
names: Similarity
messages: Belongs to the GcvT family.

89673:HTR1A
gene id: 89673:HTR1A
uniprot id: A0A7E6DA60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.
messages: Membrane
messages: dendrite

89673:LOC114503636
gene id: 89673:LOC114503636
uniprot id: A0A6J2MG81
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:GSG1L2
gene id: 89673:GSG1L2
uniprot id: A0A7E6ECS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

89673:RIMBP2
gene id: 89673:RIMBP2
uniprot id: A0A6J2KXK9
uniprot id: A0A6J2KZA4
uniprot id: A0A7E6CRT5
uniprot id: A0A7E6CRT6
uniprot id: A0A7E6CRT8
uniprot id: A0A7E6CS45
uniprot id: A0A7E6CS50
names: Similarity
messages: Belongs to the RIMBP family.

89673:NKX2-1
gene id: 89673:NKX2-1
uniprot id: A0A6J2LE09
names: Subcellular Location Annotation
messages: Nucleus

89673:DBR1
gene id: 89673:DBR1
uniprot id: A0A6J2M5A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lariat debranching enzyme family.
messages: Nucleus

89673:MYO9A
gene id: 89673:MYO9A
uniprot id: A0A6J2L8I7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

89673:LOC118498778
gene id: 89673:LOC118498778
uniprot id: A0A7E6D329
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

89673:MORF4L1
gene id: 89673:MORF4L1
uniprot id: A0A6J2KSD5
uniprot id: A0A6J2KXU8
names: Subcellular Location Annotation
messages: Nucleus

89673:SLIT1
gene id: 89673:SLIT1
uniprot id: A0A6J2LJI0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:ABCA13
gene id: 89673:ABCA13
uniprot id: A0A7E6CHM1
names: Subcellular Location Annotation
messages: Membrane

89673:SNRPG
gene id: 89673:SNRPG
uniprot id: A0A6J2LZ93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing.
messages: cytosol

89673:APC2
gene id: 89673:APC2
uniprot id: A0A6J2M7H7
uniprot id: A0A6J2MCU0
uniprot id: A0A7E6EAB5
names: Similarity
messages: Belongs to the adenomatous polyposis coli (APC) family.

89673:LOC114505269
gene id: 89673:LOC114505269
uniprot id: A0A6J2MI27
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

89673:LOC114503775
gene id: 89673:LOC114503775
uniprot id: A0A6J2MD17
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114507859
gene id: 89673:LOC114507859
uniprot id: A0A6J2MUZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114496243
gene id: 89673:LOC114496243
uniprot id: A0A7E6DXC1
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

89673:LOC114513633
gene id: 89673:LOC114513633
uniprot id: A0A6J2NF87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KRR1 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
messages: nucleolus

89673:LOC114491169
gene id: 89673:LOC114491169
uniprot id: A0A7E6D9K9
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

89673:FOXI3
gene id: 89673:FOXI3
uniprot id: A0A6J2LVY1
names: Subcellular Location Annotation
messages: Nucleus

89673:RDH8
gene id: 89673:RDH8
uniprot id: A0A6J2M4G2
uniprot id: A0A7E6EAU3
uniprot id: A0A7E6EB85
uniprot id: A0A7E6EB87
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

89673:LOC114504063
gene id: 89673:LOC114504063
uniprot id: A0A6J2MHQ4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ACAT1
gene id: 89673:ACAT1
uniprot id: A0A6J2M0K8
uniprot id: A0A7E6DZ62
uniprot id: A0A7E6E046
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

89673:B4GALT7
gene id: 89673:B4GALT7
uniprot id: A0A6J2N352
uniprot id: A0A7E6CRR5
uniprot id: A0A7E6CRU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

89673:LOC114492395
gene id: 89673:LOC114492395
uniprot id: A0A6J2L6D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

89673:GPR12
gene id: 89673:GPR12
uniprot id: A0A6J2L2R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:HSD17B11
gene id: 89673:HSD17B11
uniprot id: A0A6J2LE62
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

89673:LOC114501971
gene id: 89673:LOC114501971
uniprot id: A0A6J2M4W3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.

89673:TRMT2A
gene id: 89673:TRMT2A
uniprot id: A0A6J2MUR4
uniprot id: A0A6J2MZB5
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:GLRA3
gene id: 89673:GLRA3
uniprot id: A0A6J2MA23
uniprot id: A0A6J2MC32
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

89673:LTB4R2
gene id: 89673:LTB4R2
uniprot id: A0A6J2L7I1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:CPLX4
gene id: 89673:CPLX4
uniprot id: A0A6J2MSC0
uniprot id: A0A7E6CGA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

89673:LOC114513621
gene id: 89673:LOC114513621
uniprot id: A0A6J2NAD3
uniprot id: A0A6J2NFW0
uniprot id: A0A7E6D5S2
uniprot id: A0A7E6D8I2
names: Similarity
messages: Belongs to the SEC2 family.

89673:YTHDF3
gene id: 89673:YTHDF3
uniprot id: A0A6J2NCS6
uniprot id: A0A6J2NHN9
uniprot id: A0A6J2NI99
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

89673:PKP3
gene id: 89673:PKP3
uniprot id: A0A6J2M1T9
names: Similarity
messages: Belongs to the beta-catenin family.

89673:TP53INP2
gene id: 89673:TP53INP2
uniprot id: A0A6J2MP31
names: Subcellular Location Annotation
messages: PML body
messages: autophagosome
messages: cytosol

89673:PCBD1
gene id: 89673:PCBD1
uniprot id: A0A6J2LP49
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

89673:BMP2
gene id: 89673:BMP2
uniprot id: A0A6J2MQM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

89673:DSEL
gene id: 89673:DSEL
uniprot id: A0A6J2MKH8
names: Similarity
messages: Belongs to the dermatan-sulfate isomerase family.

89673:LOC114498948
gene id: 89673:LOC114498948
uniprot id: A0A6J2LY38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CSNK1D
gene id: 89673:CSNK1D
uniprot id: A0A6J2M7J7
uniprot id: A0A6J2M8W4
uniprot id: A0A6J2M9H6
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:SNRPD3
gene id: 89673:SNRPD3
uniprot id: A0A6J2MW67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing.
messages: cytosol

89673:NPFFR1
gene id: 89673:NPFFR1
uniprot id: A0A7E6DWJ6
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

89673:MDGA1
gene id: 89673:MDGA1
uniprot id: A0A6J2LJZ4
uniprot id: A0A7E6DLF2
uniprot id: A0A7E6DLT3
uniprot id: A0A7E6DLW2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:SGCZ
gene id: 89673:SGCZ
uniprot id: A0A6J2MY43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

89673:VTA1
gene id: 89673:VTA1
uniprot id: A0A6J2LBS3
uniprot id: A0A6J2LHM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTA1 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

89673:TEAD4
gene id: 89673:TEAD4
uniprot id: A0A7E6D564
uniprot id: A0A7E6D5B9
names: Subcellular Location Annotation
messages: Nucleus

89673:LTN1
gene id: 89673:LTN1
uniprot id: A0A6J2L063
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LTN1 family.
messages: Component of the ribosome quality control complex (RQC).
messages: E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.
messages: cytosol

89673:ARSL
gene id: 89673:ARSL
uniprot id: A0A7E6D1K1
names: Similarity
messages: Belongs to the sulfatase family.

89673:ITGA4
gene id: 89673:ITGA4
uniprot id: A0A6J2LDH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

89673:CASP7
gene id: 89673:CASP7
uniprot id: A0A6J2LSQ9
uniprot id: A0A7E6DWF3
names: Similarity
messages: Belongs to the peptidase C14A family.

89673:DPY19L4
gene id: 89673:DPY19L4
uniprot id: A0A6J2NHC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

89673:ST14
gene id: 89673:ST14
uniprot id: A0A6J2MYJ2
uniprot id: A0A7E6CVE7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S1 family.
messages: Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site.
messages: Interacts with CDCP1. May interact with TMEFF1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:TRAPPC1
gene id: 89673:TRAPPC1
uniprot id: A0A6J2NJA7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

89673:HMX2
gene id: 89673:HMX2
uniprot id: A0A6J2LP06
names: Subcellular Location Annotation
messages: Nucleus

89673:TADA3
gene id: 89673:TADA3
uniprot id: A0A6J2M799
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGG1 family.
messages: Nucleus

89673:IDH2
gene id: 89673:IDH2
uniprot id: A0A6J2KRU2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Homodimer.

89673:PEX1
gene id: 89673:PEX1
uniprot id: A0A6J2MUK7
uniprot id: A0A7E6CI09
uniprot id: A0A7E6CI60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: cytosol

89673:DONSON
gene id: 89673:DONSON
uniprot id: A0A6J2L2D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DONSON family.
messages: Nucleus

89673:ZDHHC18
gene id: 89673:ZDHHC18
uniprot id: A0A6J2LNL5
uniprot id: A0A7E6DR85
uniprot id: A0A7E6DRA6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

89673:ZHX3
gene id: 89673:ZHX3
uniprot id: A0A7E6CG30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

89673:KRT222
gene id: 89673:KRT222
uniprot id: A0A6J2MBA1
uniprot id: A0A6J2MH85
names: Similarity
messages: Belongs to the intermediate filament family.

89673:INSRR
gene id: 89673:INSRR
uniprot id: A0A6J2KTQ3
uniprot id: A0A7E6CVB4
uniprot id: A0A7E6CW34
uniprot id: A0A7E6CY40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

89673:SLCO1C1
gene id: 89673:SLCO1C1
uniprot id: A0A6J2NES7
uniprot id: A0A7E6D810
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:EDA2R
gene id: 89673:EDA2R
uniprot id: A0A6J2MG21
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:NDST1
gene id: 89673:NDST1
uniprot id: A0A6J2MZG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

89673:MOK
gene id: 89673:MOK
uniprot id: A0A7E6CSF2
uniprot id: A0A7E6CV53
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:NR2F2
gene id: 89673:NR2F2
uniprot id: A0A6J2KTK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

89673:C4H6orf89
gene id: 89673:C4H6orf89
uniprot id: A0A6J2LDZ1
uniprot id: A0A7E6DLD1
uniprot id: A0A7E6DLD5
uniprot id: A0A7E6DLR4
uniprot id: A0A7E6DLU7
uniprot id: A0A7E6DM38
uniprot id: A0A7E6DM43
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

89673:TMEM176A
gene id: 89673:TMEM176A
uniprot id: A0A6J2MW04
uniprot id: A0A7E6CIY4
names: Similarity
messages: Belongs to the TMEM176 family.

89673:UGT2A3
gene id: 89673:UGT2A3
uniprot id: A0A7E6DE92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

89673:MSTN
gene id: 89673:MSTN
uniprot id: A0A6J2LHG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts specifically as a negative regulator of skeletal muscle growth.
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked. Interacts with WFIKKN2, leading to inhibit its activity. Interacts with FSTL3.
messages: Secreted

89673:ALOX5
gene id: 89673:ALOX5
uniprot id: A0A6J2LI97
uniprot id: A0A6J2LM01
uniprot id: A0A7E6DTN5
uniprot id: A0A7E6DUB2
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:DRGX
gene id: 89673:DRGX
uniprot id: A0A6J2LRA0
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114489455
gene id: 89673:LOC114489455
uniprot id: A0A7E6CX24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

89673:MEIS2
gene id: 89673:MEIS2
uniprot id: A0A6J2L0L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

89673:LOC114498862
gene id: 89673:LOC114498862
uniprot id: A0A6J2LSD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TET3
gene id: 89673:TET3
uniprot id: A0A6J2LWK4
uniprot id: A0A7E6DY00
uniprot id: A0A7E6DYV2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TET family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Chromosome
messages: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development.
messages: The zinc ions have a structural role.

89673:IRAK2
gene id: 89673:IRAK2
uniprot id: A0A6J2M3R5
uniprot id: A0A7E6E5V5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
messages: Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.
messages: Interacts with MYD88. IL-1 stimulation leads to the formation of a signaling complex which dissociates from the IL-1 receptor following the binding of PELI1.

89673:IL23A
gene id: 89673:IL23A
uniprot id: A0A7E6D6Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

89673:MYH11
gene id: 89673:MYH11
uniprot id: A0A6J2M819
uniprot id: A0A6J2M9M7
uniprot id: A0A7E6DBN4
uniprot id: A0A7E6DDJ3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

89673:MAP3K21
gene id: 89673:MAP3K21
uniprot id: A0A7E6CYV3
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

89673:ADGRB1
gene id: 89673:ADGRB1
uniprot id: A0A7E6E700
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114513265
gene id: 89673:LOC114513265
uniprot id: A0A6J2N942
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:AGAP2
gene id: 89673:AGAP2
uniprot id: A0A6J2N6M6
uniprot id: A0A6J2NB91
uniprot id: A0A7E6D5T4
uniprot id: A0A7E6D8M9
names: Similarity
messages: Belongs to the centaurin gamma-like family.

89673:EFNA3
gene id: 89673:EFNA3
uniprot id: A0A6J2KY76
uniprot id: A0A7E6CVL3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:LOC114507406
gene id: 89673:LOC114507406
uniprot id: A0A6J2MNI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TIMM9
gene id: 89673:TIMM9
uniprot id: A0A6J2L5J4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

89673:PALM
gene id: 89673:PALM
uniprot id: A0A6J2M6C7
uniprot id: A0A6J2MB21
uniprot id: A0A6J2MBM1
uniprot id: A0A7E6E8K0
names: Similarity
messages: Belongs to the paralemmin family.

89673:SLC35A2
gene id: 89673:SLC35A2
uniprot id: A0A6J2MGD1
uniprot id: A0A6J2MGN0
uniprot id: A0A6J2MKF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

89673:ABCC9
gene id: 89673:ABCC9
uniprot id: A0A6J2N6U5
uniprot id: A0A6J2N8K7
uniprot id: A0A7E6D794
uniprot id: A0A7E6D7G5
uniprot id: A0A7E6D7Z8
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with KCNJ11.
messages: Membrane

89673:MAN2C1
gene id: 89673:MAN2C1
uniprot id: A0A6J2L325
uniprot id: A0A7E6DWC3
uniprot id: A0A7E6DWD2
uniprot id: A0A7E6DWY8
uniprot id: A0A7E6DXB8
uniprot id: A0A7E6DXQ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

89673:DNER
gene id: 89673:DNER
uniprot id: A0A6J2LH69
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:CASP10
gene id: 89673:CASP10
uniprot id: A0A6J2LDU5
uniprot id: A0A7E6DJ03
names: Similarity
messages: Belongs to the peptidase C14A family.

89673:SS18L2
gene id: 89673:SS18L2
uniprot id: A0A6J2M387
names: Similarity
messages: Belongs to the SS18 family.

89673:EWSR1
gene id: 89673:EWSR1
uniprot id: A0A6J2MUM2
uniprot id: A0A6J2MZQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TET family.
messages: Nucleus

89673:LOC114510351
gene id: 89673:LOC114510351
uniprot id: A0A6J2N482
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:IL5RA
gene id: 89673:IL5RA
uniprot id: A0A7E6E7M6
names: Subcellular Location Annotation
messages: Membrane

89673:POLA1
gene id: 89673:POLA1
uniprot id: A0A7E6D002
uniprot id: A0A7E6D005
uniprot id: A0A7E6D2S0
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

89673:RPP14
gene id: 89673:RPP14
uniprot id: A0A6J2M3F2
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.

89673:ST8SIA4
gene id: 89673:ST8SIA4
uniprot id: A0A6J2LZH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

89673:SPESP1
gene id: 89673:SPESP1
uniprot id: A0A6J2LD95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPESP1 family.
messages: Involved in fertilization ability of sperm.
messages: acrosome

89673:UPK1B
gene id: 89673:UPK1B
uniprot id: A0A6J2L2I5
uniprot id: A0A7E6D6U3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:FUT7
gene id: 89673:FUT7
uniprot id: A0A7E6DH93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

89673:COG7
gene id: 89673:COG7
uniprot id: A0A6J2LCX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG7 family.
messages: Golgi apparatus membrane
messages: Membrane

89673:TPM3
gene id: 89673:TPM3
uniprot id: A0A6J2KSB1
uniprot id: A0A6J2KSB6
uniprot id: A0A6J2KSV9
uniprot id: A0A6J2KSW4
uniprot id: A0A6J2KSW9
uniprot id: A0A6J2KUF3
uniprot id: A0A6J2KUF8
uniprot id: A0A6J2KW56
uniprot id: A0A6J2KW60
uniprot id: A0A6J2KW65
uniprot id: A0A6J2KW70
uniprot id: A0A6J2KYA5
uniprot id: A0A6J2KYA9
uniprot id: A0A6J2KYB3
uniprot id: A0A7E6CW41
uniprot id: A0A7E6CWZ2
uniprot id: A0A7E6CYU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

89673:ITGA11
gene id: 89673:ITGA11
uniprot id: A0A6J2L3W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

89673:PDHA2
gene id: 89673:PDHA2
uniprot id: A0A6J2LCD2
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.

89673:LOC114500032
gene id: 89673:LOC114500032
uniprot id: A0A6J2M2W9
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Component of the 43S pre-initiation complex (43S PIC), which binds to the mRNA cap-proximal region, scans mRNA 5'-untranslated region, and locates the initiation codon. This protein enhances formation of the cap-proximal complex. Together with EIF1, facilitates scanning, start codon recognition, promotion of the assembly of 48S complex at the initiation codon (43S PIC becomes 48S PIC after the start codon is reached), and dissociation of aberrant complexes. After start codon location, together with EIF5B orients the initiator methionine-tRNA in a conformation that allows 60S ribosomal subunit joining to form the 80S initiation complex. Is released after 80S initiation complex formation, just after GTP hydrolysis by EIF5B, and before release of EIF5B. Its globular part is located in the A site of the 40S ribosomal subunit. Its interaction with EIF5 during scanning contribute to the maintenance of EIF1 within the open 43S PIC. In contrast to yeast orthologs, does not bind EIF1.

89673:MAP4K3
gene id: 89673:MAP4K3
uniprot id: A0A6J2LRX6
uniprot id: A0A6J2LU28
uniprot id: A0A7E6DX25
uniprot id: A0A7E6DX83
uniprot id: A0A7E6DYG6
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

89673:BCOR
gene id: 89673:BCOR
uniprot id: A0A6J2MH51
uniprot id: A0A6J2MHI0
uniprot id: A0A7E6CZZ2
uniprot id: A0A7E6D0W0
names: Similarity
messages: Belongs to the BCOR family.

89673:SAP30L
gene id: 89673:SAP30L
uniprot id: A0A6J2N2R2
names: Similarity
messages: Belongs to the SAP30 family.

89673:MOGAT1
gene id: 89673:MOGAT1
uniprot id: A0A6J2LKV8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:CRABP1
gene id: 89673:CRABP1
uniprot id: A0A6J2KSE9
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

89673:FGF11
gene id: 89673:FGF11
uniprot id: A0A6J2NEI9
uniprot id: A0A6J2NJP0
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

89673:MAP3K9
gene id: 89673:MAP3K9
uniprot id: A0A6J2L9E2
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

89673:SUGT1
gene id: 89673:SUGT1
uniprot id: A0A6J2MWU9
names: Similarity
messages: Belongs to the SGT1 family.

89673:FEN1
gene id: 89673:FEN1
uniprot id: A0A6J2LSZ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Mitochondrion
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
messages: nucleolus
messages: nucleoplasm

89673:FAM135B
gene id: 89673:FAM135B
uniprot id: A0A6J2NCZ0
names: Similarity
messages: Belongs to the FAM135 family.

89673:LOC114490954
gene id: 89673:LOC114490954
uniprot id: A0A6J2KZP3
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Component of the 43S pre-initiation complex (43S PIC), which binds to the mRNA cap-proximal region, scans mRNA 5'-untranslated region, and locates the initiation codon. This protein enhances formation of the cap-proximal complex. Together with EIF1, facilitates scanning, start codon recognition, promotion of the assembly of 48S complex at the initiation codon (43S PIC becomes 48S PIC after the start codon is reached), and dissociation of aberrant complexes. After start codon location, together with EIF5B orients the initiator methionine-tRNA in a conformation that allows 60S ribosomal subunit joining to form the 80S initiation complex. Is released after 80S initiation complex formation, just after GTP hydrolysis by EIF5B, and before release of EIF5B. Its globular part is located in the A site of the 40S ribosomal subunit. Its interaction with EIF5 during scanning contribute to the maintenance of EIF1 within the open 43S PIC. In contrast to yeast orthologs, does not bind EIF1.

89673:ACOT8
gene id: 89673:ACOT8
uniprot id: A0A6J2MQK9
uniprot id: A0A7E6CFN9
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

89673:LOC114490147
gene id: 89673:LOC114490147
uniprot id: A0A6J2KZ28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the C19orf12 family.
messages: Mitochondrion membrane

89673:CCNP
gene id: 89673:CCNP
uniprot id: A0A7E6CLL4
names: Similarity
messages: Belongs to the cyclin family.

89673:PLPP2
gene id: 89673:PLPP2
uniprot id: A0A6J2M6F0
uniprot id: A0A7E6E8I7
uniprot id: A0A7E6EA66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

89673:NR0B1
gene id: 89673:NR0B1
uniprot id: A0A6J2MFQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus
messages: Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency.

89673:LOC114510642
gene id: 89673:LOC114510642
uniprot id: A0A6J2N438
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:CD247
gene id: 89673:CD247
uniprot id: A0A7E6CWD8
uniprot id: A0A7E6CWP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD3Z/FCER1G family.
messages: Cell membrane
messages: Membrane

89673:METTL15
gene id: 89673:METTL15
uniprot id: A0A6J2M1S7
uniprot id: A0A7E6E181
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmH family.

89673:MESD
gene id: 89673:MESD
uniprot id: A0A6J2KVC9
uniprot id: A0A7E6CSJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MESD family.
messages: Endoplasmic reticulum

89673:LOC114500148
gene id: 89673:LOC114500148
uniprot id: A0A6J2M3D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ATP5MD
gene id: 89673:ATP5MD
uniprot id: A0A6J2N9K8
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion membrane

89673:TTC26
gene id: 89673:TTC26
uniprot id: A0A6J2MM87
names: Similarity
messages: Belongs to the IFT56 family.

89673:PLA2G1B
gene id: 89673:PLA2G1B
uniprot id: A0A6J2MTS0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

89673:PPARGC1B
gene id: 89673:PPARGC1B
uniprot id: A0A6J2N215
uniprot id: A0A7E6CU79
names: Subcellular Location Annotation
messages: Nucleus

89673:BNIP1
gene id: 89673:BNIP1
uniprot id: A0A6J2MX26
names: Subcellular Location Annotation
messages: Membrane

89673:PFDN2
gene id: 89673:PFDN2
uniprot id: A0A6J2KX14
uniprot id: A0A7E6CXM5
names: Function
names: Similarity
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

89673:SLC2A9
gene id: 89673:SLC2A9
uniprot id: A0A6J2L7X5
uniprot id: A0A6J2LBV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane

89673:VIPR1
gene id: 89673:VIPR1
uniprot id: A0A6J2M4U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

89673:CBL
gene id: 89673:CBL
uniprot id: A0A6J2M281
uniprot id: A0A7E6DYN1
uniprot id: A0A7E6DZJ2
names: Domain
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

89673:SPOCK3
gene id: 89673:SPOCK3
uniprot id: A0A6J2MA98
uniprot id: A0A6J2MFC7
uniprot id: A0A6J2MFT2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114507593
gene id: 89673:LOC114507593
uniprot id: A0A7E6CIQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs. Binds with high affinity to IPO4. Interacts with DDIT3.
messages: Cytoplasm
messages: May play a role during erythropoiesis through regulation of transcription factor DDIT3.
messages: Nucleus
messages: nucleolus

89673:LOC114499024
gene id: 89673:LOC114499024
uniprot id: A0A6J2LTX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SLC1A6
gene id: 89673:SLC1A6
uniprot id: A0A6J2MB59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

89673:PPIL4
gene id: 89673:PPIL4
uniprot id: A0A6J2LH88
uniprot id: A0A7E6DPC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.
messages: Nucleus
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

89673:ARSB
gene id: 89673:ARSB
uniprot id: A0A6J2MXM0
uniprot id: A0A7E6DAI7
names: Similarity
messages: Belongs to the sulfatase family.

89673:CHRNA3
gene id: 89673:CHRNA3
uniprot id: A0A6J2KV78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

89673:MAPK4
gene id: 89673:MAPK4
uniprot id: A0A6J2MM09
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

89673:BTC
gene id: 89673:BTC
uniprot id: A0A7E6DG38
uniprot id: A0A7E6DG42
uniprot id: A0A7E6DGC2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:PPP1R14A
gene id: 89673:PPP1R14A
uniprot id: A0A6J2N223
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP1 inhibitor family.
messages: Cytoplasm
messages: Inhibitor of PPP1CA.

89673:SLC8A2
gene id: 89673:SLC8A2
uniprot id: A0A6J2N7Y6
uniprot id: A0A7E6CNA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

89673:LOC114491737
gene id: 89673:LOC114491737
uniprot id: A0A6J2L7X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ABCB10
gene id: 89673:ABCB10
uniprot id: A0A6J2N5T2
names: Subcellular Location Annotation
messages: Membrane

89673:ST6GALNAC1
gene id: 89673:ST6GALNAC1
uniprot id: A0A7E6EF84
uniprot id: A0A7E6EFI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

89673:LOC118499951
gene id: 89673:LOC118499951
uniprot id: A0A7E6DHD6
names: Similarity
messages: Belongs to the TMA7 family.

89673:UBA3
gene id: 89673:UBA3
uniprot id: A0A6J2M6T9
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
messages: Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.

89673:SPATA18
gene id: 89673:SPATA18
uniprot id: A0A7E6DAJ2
uniprot id: A0A7E6DD73
uniprot id: A0A7E6DD76
uniprot id: A0A7E6DD80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIEAP family.
messages: Cytoplasm
messages: Membrane
messages: Mitochondrion outer membrane

89673:LOC114511891
gene id: 89673:LOC114511891
uniprot id: A0A6J2N3U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOR1AIP family.
messages: Membrane

89673:MYC
gene id: 89673:MYC
uniprot id: A0A6J2NCU8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). Positively regulates transcription of HNRNPA1, HNRNPA2 and PTBP1 which in turn regulate splicing of pyruvate kinase PKM by binding repressively to sequences flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform.
messages: nucleolus
messages: nucleoplasm

89673:LOC114506120
gene id: 89673:LOC114506120
uniprot id: A0A6J2MH35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase g subunit family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.

89673:CAMK4
gene id: 89673:CAMK4
uniprot id: A0A6J2N1K7
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:TENT5C
gene id: 89673:TENT5C
uniprot id: A0A6J2KX22
names: Similarity
messages: Belongs to the TENT family.

89673:CDK19
gene id: 89673:CDK19
uniprot id: A0A7E6DMS6
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:COPG1
gene id: 89673:COPG1
uniprot id: A0A6J2MNI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

89673:SCARF2
gene id: 89673:SCARF2
uniprot id: A0A6J2MVG1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:AKAP8
gene id: 89673:AKAP8
uniprot id: A0A6J2MAJ5
uniprot id: A0A7E6E9N8
uniprot id: A0A7E6EAG8
uniprot id: A0A7E6EAN7
uniprot id: A0A7E6EBB4
uniprot id: A0A7E6EBN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AKAP95 family.
messages: Nucleus matrix

89673:PTCH2
gene id: 89673:PTCH2
uniprot id: A0A6J2LNZ7
uniprot id: A0A6J2LPY3
uniprot id: A0A7E6DRL5
uniprot id: A0A7E6DSA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

89673:ADGRG6
gene id: 89673:ADGRG6
uniprot id: A0A6J2LFY8
uniprot id: A0A7E6DNH8
uniprot id: A0A7E6DNX2
uniprot id: A0A7E6DP41
uniprot id: A0A7E6DPE8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:LOC114501604
gene id: 89673:LOC114501604
uniprot id: A0A7E6E431
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:NMUR1
gene id: 89673:NMUR1
uniprot id: A0A6J2LAV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

89673:LOC114500261
gene id: 89673:LOC114500261
uniprot id: A0A6J2LZD7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:RPL18
gene id: 89673:RPL18
uniprot id: A0A6J2N5V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL18 family.
messages: Rough endoplasmic reticulum

89673:LOC114494586
gene id: 89673:LOC114494586
uniprot id: A0A6J2LF77
uniprot id: A0A7E6DKY3
uniprot id: A0A7E6DLA6
uniprot id: A0A7E6DLN1
names: Caution
names: Similarity
messages: Belongs to the palmitoyl-protein thioesterase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:NT5DC3
gene id: 89673:NT5DC3
uniprot id: A0A6J2NDP9
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

89673:LOC114513025
gene id: 89673:LOC114513025
uniprot id: A0A6J2N7R9
names: Similarity
messages: Belongs to the intermediate filament family.

89673:RPS9
gene id: 89673:RPS9
uniprot id: A0A7E6CR28
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

89673:LOC114505201
gene id: 89673:LOC114505201
uniprot id: A0A7E6D235
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

89673:SNAPIN
gene id: 89673:SNAPIN
uniprot id: A0A6J2KX42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAPIN family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling.
messages: synaptic vesicle membrane

89673:POP7
gene id: 89673:POP7
uniprot id: A0A6J2MNB3
uniprot id: A0A7E6DBG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone-like Alba family.
messages: Component of nuclear RNase P and RNase MRP complexes. RNase P consists of a catalytic RNA moiety and 10 different protein chains; POP1, POP4, POP5, POP7, RPP14, RPP21, RPP25, RPP30, RPP38 and RPP40. Within the RNase P complex, POP1, POP7 and RPP25 form the 'finger' subcomplex, POP5, RPP14, RPP40 and homodimeric RPP30 form the 'palm' subcomplex, and RPP21, POP4 and RPP38 form the 'wrist' subcomplex. All subunits of the RNase P complex interact with the catalytic RNA. Several subunits of RNase P are also part of the RNase MRP complex. RNase MRP consists of a catalytic RNA moiety and about 8 protein subunits; POP1, POP7, RPP25, RPP30, RPP38, RPP40 and possibly also POP4 and POP5. Interacts with SMN1. POP7 forms a heterodimer with RPP25 that binds to the P3 stem loop of the catalytic RNA.
messages: Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences.
messages: Cytoplasmic granule
messages: nucleolus

89673:GPR157
gene id: 89673:GPR157
uniprot id: A0A6J2LN53
names: Subcellular Location Annotation
messages: Membrane

89673:MAGI2
gene id: 89673:MAGI2
uniprot id: A0A6J2MPR4
uniprot id: A0A6J2MUD3
uniprot id: A0A7E6CI03
names: Subcellular Location Annotation
messages: Membrane

89673:GRIN1
gene id: 89673:GRIN1
uniprot id: A0A6J2LZW3
uniprot id: A0A6J2M151
uniprot id: A0A6J2M189
uniprot id: A0A6J2M4Y0
uniprot id: A0A6J2M4Z0
uniprot id: A0A6J2M5G5
uniprot id: A0A7E6DH92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

89673:LOC114490730
gene id: 89673:LOC114490730
uniprot id: A0A6J2L4H7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:CAMK1D
gene id: 89673:CAMK1D
uniprot id: A0A6J2L8Z8
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:ELP1
gene id: 89673:ELP1
uniprot id: A0A6J2LNA9
uniprot id: A0A7E6DFY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP1/IKA1 family.
messages: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
messages: Cytoplasm
messages: Nucleus

89673:CA10
gene id: 89673:CA10
uniprot id: A0A6J2MFE2
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Does not have a catalytic activity.

89673:LOC114507405
gene id: 89673:LOC114507405
uniprot id: A0A6J2MSX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SCN4A
gene id: 89673:SCN4A
uniprot id: A0A6J2MAZ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

89673:SNCB
gene id: 89673:SNCB
uniprot id: A0A6J2N1U2
names: Similarity
messages: Belongs to the synuclein family.

89673:ITIH2
gene id: 89673:ITIH2
uniprot id: A0A6J2LCT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

89673:LOC114512241
gene id: 89673:LOC114512241
uniprot id: A0A6J2NAD5
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:CEP57
gene id: 89673:CEP57
uniprot id: A0A6J2M298
names: Similarity
messages: Belongs to the translokin family.

89673:LOC114491805
gene id: 89673:LOC114491805
uniprot id: A0A6J2L718
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates IFNG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.

89673:VGLL2
gene id: 89673:VGLL2
uniprot id: A0A6J2LER0
uniprot id: A0A7E6DMX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: Nucleus

89673:GNPTAB
gene id: 89673:GNPTAB
uniprot id: A0A6J2NCR3
uniprot id: A0A7E6D7Y1
uniprot id: A0A7E6D839
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the stealth family.
messages: Membrane

89673:AQP11
gene id: 89673:AQP11
uniprot id: A0A6J2M2B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

89673:P4HB
gene id: 89673:P4HB
uniprot id: A0A6J2M858
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

89673:RHBDF1
gene id: 89673:RHBDF1
uniprot id: A0A6J2LYA6
uniprot id: A0A7E6DCG8
uniprot id: A0A7E6DCN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

89673:KRT1
gene id: 89673:KRT1
uniprot id: A0A6J2N6D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intermediate filament family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

89673:LOC114490213
gene id: 89673:LOC114490213
uniprot id: A0A6J2KWZ1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CHL1
gene id: 89673:CHL1
uniprot id: A0A6J2M2T7
names: Similarity
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.

89673:TMEM94
gene id: 89673:TMEM94
uniprot id: A0A6J2M748
uniprot id: A0A6J2M915
uniprot id: A0A6J2MBT7
uniprot id: A0A7E6EEJ2
uniprot id: A0A7E6EG47
uniprot id: A0A7E6EGA8
names: Subcellular Location Annotation
messages: Membrane

89673:SPI1
gene id: 89673:SPI1
uniprot id: A0A6J2LVX2
uniprot id: A0A6J2M1E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

89673:NDUFA3
gene id: 89673:NDUFA3
uniprot id: A0A6J2N1P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA3 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Membrane
messages: Mitochondrion inner membrane

89673:LOC114503300
gene id: 89673:LOC114503300
uniprot id: A0A7E6EGB1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114489526
gene id: 89673:LOC114489526
uniprot id: A0A6J2KV77
uniprot id: A0A7E6CX10
names: Subcellular Location Annotation
messages: Membrane

89673:PHF1
gene id: 89673:PHF1
uniprot id: A0A6J2LAZ8
uniprot id: A0A7E6DL47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus

89673:PTGR2
gene id: 89673:PTGR2
uniprot id: A0A7E6CLS7
uniprot id: A0A7E6CLT1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADP-dependent oxidoreductase L4BD family.
messages: Cytoplasm
messages: Monomer.

89673:CHRDL1
gene id: 89673:CHRDL1
uniprot id: A0A7E6D1F2
uniprot id: A0A7E6D274
uniprot id: A0A7E6D415
names: Subcellular Location Annotation
messages: Secreted

89673:NDUFB4
gene id: 89673:NDUFB4
uniprot id: A0A6J2L412
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB4 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

89673:C5H1orf52
gene id: 89673:C5H1orf52
uniprot id: A0A7E6DTE6
names: Similarity
messages: Belongs to the UPF0690 family.

89673:ELP2
gene id: 89673:ELP2
uniprot id: A0A6J2MP58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ELP2 family.
messages: Cytoplasm
messages: Nucleus

89673:TMEM14A
gene id: 89673:TMEM14A
uniprot id: A0A6J2LI89
uniprot id: A0A7E6DMN1
names: Similarity
messages: Belongs to the TMEM14 family.

89673:LOC114500203
gene id: 89673:LOC114500203
uniprot id: A0A6J2LY16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:HS2ST1
gene id: 89673:HS2ST1
uniprot id: A0A6J2LJR5
uniprot id: A0A6J2LP44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Golgi apparatus membrane
messages: Membrane

89673:FXR1
gene id: 89673:FXR1
uniprot id: A0A6J2L0B1
uniprot id: A0A6J2L1X4
uniprot id: A0A6J2L3V9
uniprot id: A0A6J2L3W5
uniprot id: A0A6J2L5C8
uniprot id: A0A7E6D2W8
uniprot id: A0A7E6D3M7
uniprot id: A0A7E6D5Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMR1 family.
messages: Cytoplasmic ribonucleoprotein granule
messages: Nucleus envelope
messages: Postsynapse
messages: Synapse
messages: dendritic spine

89673:DLGAP1
gene id: 89673:DLGAP1
uniprot id: A0A6J2MK28
uniprot id: A0A6J2MKE7
uniprot id: A0A6J2MPA2
uniprot id: A0A6J2MPA8
uniprot id: A0A6J2MPH9
uniprot id: A0A7E6CDT8
uniprot id: A0A7E6CDZ7
uniprot id: A0A7E6CEJ2
uniprot id: A0A7E6CG34
names: Similarity
messages: Belongs to the SAPAP family.

89673:EBNA1BP2
gene id: 89673:EBNA1BP2
uniprot id: A0A6J2LTG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP2 family.
messages: Required for the processing of the 27S pre-rRNA.
messages: nucleolus

89673:LOC114509108
gene id: 89673:LOC114509108
uniprot id: A0A6J2MTW5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:ARSI
gene id: 89673:ARSI
uniprot id: A0A6J2N0V3
names: Similarity
messages: Belongs to the sulfatase family.

89673:DBH
gene id: 89673:DBH
uniprot id: A0A6J2MSD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the copper type II ascorbate-dependent monooxygenase family.
messages: Conversion of dopamine to noradrenaline.
messages: Homotetramer; composed of two disulfide-linked dimers.
messages: chromaffin granule lumen
messages: chromaffin granule membrane
messages: secretory vesicle lumen
messages: secretory vesicle membrane

89673:LYRM1
gene id: 89673:LYRM1
uniprot id: A0A6J2NAQ6
uniprot id: A0A7E6DE37
uniprot id: A0A7E6DE74
names: Similarity
messages: Belongs to the complex I LYR family.

89673:PTDSS2
gene id: 89673:PTDSS2
uniprot id: A0A6J2LYM5
uniprot id: A0A7E6E472
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:LOC114511145
gene id: 89673:LOC114511145
uniprot id: A0A6J2N182
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:AGK
gene id: 89673:AGK
uniprot id: A0A6J2MPQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AGK family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

89673:KCNA3
gene id: 89673:KCNA3
uniprot id: A0A6J2KWI6
names: Subcellular Location Annotation
messages: Membrane

89673:MCEE
gene id: 89673:MCEE
uniprot id: A0A6J2KS40
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

89673:PPP2R5E
gene id: 89673:PPP2R5E
uniprot id: A0A6J2L695
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

89673:LOC114498878
gene id: 89673:LOC114498878
uniprot id: A0A6J2LTP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:GSPT2
gene id: 89673:GSPT2
uniprot id: A0A6J2MK84
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

89673:CAV1
gene id: 89673:CAV1
uniprot id: A0A6J2MQ92
uniprot id: A0A6J2MUY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

89673:ATP1A2
gene id: 89673:ATP1A2
uniprot id: A0A6J2N839
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:TGM5
gene id: 89673:TGM5
uniprot id: A0A6J2LD42
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

89673:TAGLN3
gene id: 89673:TAGLN3
uniprot id: A0A6J2KY00
names: Similarity
messages: Belongs to the calponin family.

89673:GBA2
gene id: 89673:GBA2
uniprot id: A0A6J2N1E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the non-lysosomal glucosylceramidase family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.

89673:NUDT5
gene id: 89673:NUDT5
uniprot id: A0A6J2L2S4
uniprot id: A0A7E6DMN2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

89673:LOC114515045
gene id: 89673:LOC114515045
uniprot id: A0A7E6EBM1
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

89673:LOC114499464
gene id: 89673:LOC114499464
uniprot id: A0A6J2LVT5
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: Involved in oxygen transport from the lung to the various peripheral tissues.

89673:CFAP45
gene id: 89673:CFAP45
uniprot id: A0A6J2N992
uniprot id: A0A7E6D023
names: Similarity
messages: Belongs to the CFAP45 family.

89673:SEC11A
gene id: 89673:SEC11A
uniprot id: A0A6J2KTW6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Component of the signal peptidase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:DOCK6
gene id: 89673:DOCK6
uniprot id: A0A6J2M4P9
uniprot id: A0A6J2M6E0
uniprot id: A0A6J2MAB8
uniprot id: A0A7E6EFR7
uniprot id: A0A7E6EG34
names: Similarity
messages: Belongs to the DOCK family.

89673:NUDT1
gene id: 89673:NUDT1
uniprot id: A0A6J2N1E3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Monomer.
messages: Nucleus

89673:LOC114510118
gene id: 89673:LOC114510118
uniprot id: A0A6J2N317
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:WNT7B
gene id: 89673:WNT7B
uniprot id: A0A6J2N911
uniprot id: A0A6J2NE19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

89673:CHRDL2
gene id: 89673:CHRDL2
uniprot id: A0A6J2LXH0
names: Subcellular Location Annotation
messages: Secreted

89673:NLGN3
gene id: 89673:NLGN3
uniprot id: A0A6J2MHV6
uniprot id: A0A6J2ML42
uniprot id: A0A6J2MLV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

89673:LOC114494581
gene id: 89673:LOC114494581
uniprot id: A0A6J2LF71
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

89673:PARL
gene id: 89673:PARL
uniprot id: A0A6J2L3A1
names: Subcellular Location Annotation
messages: Membrane

89673:CLPS
gene id: 89673:CLPS
uniprot id: A0A6J2LM68
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.
messages: Enterostatin has a biological activity as a satiety signal.
messages: Forms a 1:1 stoichiometric complex with pancreatic lipase.
messages: Secreted

89673:LOC114512406
gene id: 89673:LOC114512406
uniprot id: A0A6J2N3U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

89673:YEATS2
gene id: 89673:YEATS2
uniprot id: A0A6J2L0F2
uniprot id: A0A6J2L236
uniprot id: A0A7E6D3P2
uniprot id: A0A7E6D5T0
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114489919
gene id: 89673:LOC114489919
uniprot id: A0A7E6D320
uniprot id: A0A7E6D347
uniprot id: A0A7E6D3N7
uniprot id: A0A7E6D3R5
names: Subcellular Location Annotation
messages: Nucleus

89673:LDLRAD1
gene id: 89673:LDLRAD1
uniprot id: A0A6J2LV65
uniprot id: A0A7E6DSS3
uniprot id: A0A7E6DTA0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:ART5
gene id: 89673:ART5
uniprot id: A0A6J2LXZ3
uniprot id: A0A6J2LYX6
uniprot id: A0A7E6E003
uniprot id: A0A7E6E148
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

89673:UPP1
gene id: 89673:UPP1
uniprot id: A0A6J2M3P2
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

89673:LOC114512096
gene id: 89673:LOC114512096
uniprot id: A0A6J2N4L3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

89673:LOC114512278
gene id: 89673:LOC114512278
uniprot id: A0A6J2NAH9
uniprot id: A0A7E6CY09
names: Similarity
messages: Belongs to the COX20 family.

89673:IL17A
gene id: 89673:IL17A
uniprot id: A0A6J2LFL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

89673:CD14
gene id: 89673:CD14
uniprot id: A0A7E6CS67
names: Subcellular Location Annotation
messages: Cell membrane
messages: Golgi apparatus
messages: Membrane raft
messages: Secreted

89673:ELL3
gene id: 89673:ELL3
uniprot id: A0A7E6EC25
uniprot id: A0A7E6EC34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

89673:ELF1
gene id: 89673:ELF1
uniprot id: A0A6J2MQ85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

89673:USP39
gene id: 89673:USP39
uniprot id: A0A6J2LWW3
names: Subcellular Location Annotation
messages: Nucleus

89673:CDADC1
gene id: 89673:CDADC1
uniprot id: A0A6J2MQ70
uniprot id: A0A7E6CK33
uniprot id: A0A7E6CK51
uniprot id: A0A7E6CK61
uniprot id: A0A7E6CM64
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

89673:ZFYVE9
gene id: 89673:ZFYVE9
uniprot id: A0A6J2LIG4
uniprot id: A0A6J2LMY2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Early endosome membrane

89673:DDX50
gene id: 89673:DDX50
uniprot id: A0A6J2LI88
uniprot id: A0A6J2LJJ5
uniprot id: A0A7E6DUB9
uniprot id: A0A7E6DVI1
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.

89673:EFNB2
gene id: 89673:EFNB2
uniprot id: A0A6J2MRF6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:STARD9
gene id: 89673:STARD9
uniprot id: A0A6J2L5M2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

89673:LOC114512740
gene id: 89673:LOC114512740
uniprot id: A0A6J2N730
uniprot id: A0A7E6DG89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:PGLYRP1
gene id: 89673:PGLYRP1
uniprot id: A0A6J2N1Y1
names: Function
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
messages: Innate immunity protein that plays several important functions in antimicrobial and antitumor defense systems.

89673:LOC114511290
gene id: 89673:LOC114511290
uniprot id: A0A7E6CP52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lambda interferon family.
messages: Secreted

89673:MLH1
gene id: 89673:MLH1
uniprot id: A0A6J2M455
uniprot id: A0A7E6E4X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: Nucleus

89673:LOC114509942
gene id: 89673:LOC114509942
uniprot id: A0A6J2MW10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:PPME1
gene id: 89673:PPME1
uniprot id: A0A6J2LX77
uniprot id: A0A6J2M0M7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily.
messages: Binds PPP2CA and PPP2CB.
messages: Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA. Binding to PPP2CA displaces the manganese ion and inactivates the enzyme.

89673:VPS37D
gene id: 89673:VPS37D
uniprot id: A0A6J2N6T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

89673:GK2
gene id: 89673:GK2
uniprot id: A0A6J2L832
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FGGY kinase family.
messages: Cytoplasm

89673:RTN2
gene id: 89673:RTN2
uniprot id: A0A6J2N7A6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:THRB
gene id: 89673:THRB
uniprot id: A0A6J2M742
uniprot id: A0A7E6E749
uniprot id: A0A7E6E753
uniprot id: A0A7E6E7P5
uniprot id: A0A7E6E806
uniprot id: A0A7E6E8L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

89673:AKT3
gene id: 89673:AKT3
uniprot id: A0A6J2N9Z9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

89673:KRI1
gene id: 89673:KRI1
uniprot id: A0A6J2M745
names: Similarity
messages: Belongs to the KRI1 family.

89673:LOC114491859
gene id: 89673:LOC114491859
uniprot id: A0A7E6DDY1
uniprot id: A0A7E6DDZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Membrane

89673:TNK2
gene id: 89673:TNK2
uniprot id: A0A6J2KZ43
uniprot id: A0A7E6D4D9
uniprot id: A0A7E6D4F4
uniprot id: A0A7E6D4H9
uniprot id: A0A7E6D4J1
uniprot id: A0A7E6D4K8
uniprot id: A0A7E6D4L5
uniprot id: A0A7E6D4M1
uniprot id: A0A7E6D528
uniprot id: A0A7E6D539
uniprot id: A0A7E6D549
uniprot id: A0A7E6D783
uniprot id: A0A7E6D795
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Nucleus

89673:FGF8
gene id: 89673:FGF8
uniprot id: A0A6J2LKA2
uniprot id: A0A6J2LLJ1
uniprot id: A0A6J2LMK1
uniprot id: A0A6J2LQP4
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

89673:HUS1B
gene id: 89673:HUS1B
uniprot id: A0A7E6DUQ5
names: Similarity
messages: Belongs to the HUS1 family.

89673:FER1L5
gene id: 89673:FER1L5
uniprot id: A0A7E6E2S2
names: Similarity
messages: Belongs to the ferlin family.

89673:FRZB
gene id: 89673:FRZB
uniprot id: A0A6J2LEE8
names: Caution
names: Function
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development.

89673:LIAS
gene id: 89673:LIAS
uniprot id: A0A6J2L6M7
uniprot id: A0A7E6D8X4
uniprot id: A0A7E6D931
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion

89673:SYCP2
gene id: 89673:SYCP2
uniprot id: A0A7E6CEJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYCP2 family.
messages: Nucleus

89673:FGD6
gene id: 89673:FGD6
uniprot id: A0A6J2N9F3
uniprot id: A0A7E6DAN3
names: Subcellular Location Annotation
messages: cytoskeleton

89673:SEMA6B
gene id: 89673:SEMA6B
uniprot id: A0A6J2M765
uniprot id: A0A7E6E8Y6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:CSF2
gene id: 89673:CSF2
uniprot id: A0A6J2MYG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GM-CSF family.
messages: Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.
messages: Monomer. The signaling GM-CSF receptor complex is a dodecamer of two head-to-head hexamers of two alpha, two beta, and two ligand subunits.
messages: Secreted

89673:TNF
gene id: 89673:TNF
uniprot id: A0A6J2LJY4
uniprot id: A0A7E6DL56
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tumor necrosis factor family.
messages: Cell membrane
messages: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces GKAP42 protein degradation in adipocytes which is partially responsible for TNF-induced insulin resistance. Plays a role in angiogenesis by inducing VEGF production synergistically with IL1B and IL6.
messages: Homotrimer. Interacts with SPPL2B.
messages: Membrane
messages: O-glycosylated; glycans contain galactose, N-acetylgalactosamine and N-acetylneuraminic acid.
messages: Secreted
messages: The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.
messages: The membrane form, but not the soluble form, is phosphorylated on serine residues. Dephosphorylation of the membrane form occurs by binding to soluble TNFRSF1A/TNFR1.
messages: The soluble form derives from the membrane form by proteolytic processing. The membrane-bound form is further proteolytically processed by SPPL2A or SPPL2B through regulated intramembrane proteolysis producing TNF intracellular domains (ICD1 and ICD2) released in the cytosol and TNF C-domain 1 and C-domain 2 secreted into the extracellular space.

89673:TTI2
gene id: 89673:TTI2
uniprot id: A0A6J2MRD9
uniprot id: A0A7E6CKS7
uniprot id: A0A7E6CMW9
names: Similarity
messages: Belongs to the TTI2 family.

89673:PLSCR5
gene id: 89673:PLSCR5
uniprot id: A0A7E6CXE2
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

89673:SLC35A5
gene id: 89673:SLC35A5
uniprot id: A0A6J2KYG5
uniprot id: A0A7E6D422
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

89673:LOC114500711
gene id: 89673:LOC114500711
uniprot id: A0A7E6DAI2
names: Subcellular Location Annotation
messages: Nucleus

89673:CLDN12
gene id: 89673:CLDN12
uniprot id: A0A6J2MQA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Membrane
messages: tight junction

89673:ARMC8
gene id: 89673:ARMC8
uniprot id: A0A6J2M3R1
uniprot id: A0A6J2M5D7
uniprot id: A0A7E6E4S3
uniprot id: A0A7E6E5E5
uniprot id: A0A7E6E5I2
uniprot id: A0A7E6E6D0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

89673:LOC114504788
gene id: 89673:LOC114504788
uniprot id: A0A6J2MGL7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

89673:TAS1R2
gene id: 89673:TAS1R2
uniprot id: A0A6J2LQE1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:GALNT2
gene id: 89673:GALNT2
uniprot id: A0A6J2N5N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

89673:PEPD
gene id: 89673:PEPD
uniprot id: A0A6J2N358
uniprot id: A0A7E6CNB2
names: Similarity
messages: Belongs to the peptidase M24B family.

89673:LSM2
gene id: 89673:LSM2
uniprot id: A0A6J2LIK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: Nucleus

89673:GIPC3
gene id: 89673:GIPC3
uniprot id: A0A6J2M6X9
uniprot id: A0A7E6EGP3
names: Similarity
messages: Belongs to the GIPC family.

89673:FAM72A
gene id: 89673:FAM72A
uniprot id: A0A6J2N452
uniprot id: A0A6J2N9K3
uniprot id: A0A7E6CWR3
names: Similarity
messages: Belongs to the FAM72 family.

89673:C3H16orf91
gene id: 89673:C3H16orf91
uniprot id: A0A6J2M5Q9
names: Similarity
messages: Belongs to the UQCC4 family.

89673:QRSL1
gene id: 89673:QRSL1
uniprot id: A0A6J2LGS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

89673:LOC114512171
gene id: 89673:LOC114512171
uniprot id: A0A6J2N332
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

89673:FABP6
gene id: 89673:FABP6
uniprot id: A0A6J2MWX5
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

89673:MAPK9
gene id: 89673:MAPK9
uniprot id: A0A6J2N0V0
uniprot id: A0A7E6CU62
uniprot id: A0A7E6CV01
uniprot id: A0A7E6CWZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

89673:ACSL1
gene id: 89673:ACSL1
uniprot id: A0A6J2MRW5
uniprot id: A0A6J2MRX3
uniprot id: A0A7E6CL62
uniprot id: A0A7E6CL75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.
messages: Endoplasmic reticulum membrane
messages: Mitochondrion outer membrane

89673:BRF1
gene id: 89673:BRF1
uniprot id: A0A6J2L748
names: Similarity
messages: Belongs to the TFIIB family.

89673:GCNT1
gene id: 89673:GCNT1
uniprot id: A0A6J2MXR1
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

89673:SELL
gene id: 89673:SELL
uniprot id: A0A6J2N2P5
uniprot id: A0A7E6CVR5
uniprot id: A0A7E6CYH8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the selectin/LECAM family.
messages: Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia.
messages: Cell membrane
messages: Interaction with SELPLG/PSGL1 and PODXL2 is required for promoting recruitment and rolling of leukocytes. This interaction is dependent on the sialyl Lewis X glycan modification of SELPLG and PODXL2, and tyrosine sulfation modifications of SELPLG. Sulfation on 'Tyr-51' of SELPLG is important for L-selectin binding.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:LOC114489884
gene id: 89673:LOC114489884
uniprot id: A0A6J2KWF1
uniprot id: A0A6J2KZP5
uniprot id: A0A7E6D1L9
uniprot id: A0A7E6D2H1
uniprot id: A0A7E6D4C7
names: Subcellular Location Annotation
messages: Nucleus

89673:DKC1
gene id: 89673:DKC1
uniprot id: A0A6J2MH32
uniprot id: A0A7E6D0U5
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

89673:ABCB5
gene id: 89673:ABCB5
uniprot id: A0A6J2MSP8
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114507918
gene id: 89673:LOC114507918
uniprot id: A0A6J2MNH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CUL2
gene id: 89673:CUL2
uniprot id: A0A7E6DWI6
names: Similarity
messages: Belongs to the cullin family.

89673:FAM160A1
gene id: 89673:FAM160A1
uniprot id: A0A6J2MEV6
names: Similarity
messages: Belongs to the FHIP family.

89673:ENAH
gene id: 89673:ENAH
uniprot id: A0A6J2N9P6
uniprot id: A0A7E6CYB1
uniprot id: A0A7E6CYF8
uniprot id: A0A7E6CYG2
uniprot id: A0A7E6CYR8
uniprot id: A0A7E6CZ85
uniprot id: A0A7E6D0Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ena/VASP family.
messages: cytoskeleton

89673:LOC114498071
gene id: 89673:LOC114498071
uniprot id: A0A6J2LVS6
names: Similarity
messages: Belongs to the peptidase M16 family.

89673:ITM2C
gene id: 89673:ITM2C
uniprot id: A0A6J2LHX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

89673:RNASE12
gene id: 89673:RNASE12
uniprot id: A0A7E6E697
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

89673:MXRA8
gene id: 89673:MXRA8
uniprot id: A0A6J2LLV6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:TLR3
gene id: 89673:TLR3
uniprot id: A0A7E6CL36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

89673:NDUFV3
gene id: 89673:NDUFV3
uniprot id: A0A6J2L1L5
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. May be the terminally assembled subunit of Complex I.
messages: Belongs to the complex I NDUFV3 subunit family.
messages: Complex I is composed of 45 different subunits. This is a component of the flavoprotein-sulfur (FP) fragment of the enzyme.

89673:ZAR1
gene id: 89673:ZAR1
uniprot id: A0A6J2L2X0
names: Similarity
names: Subunit
messages: Belongs to the ZAR1 family.
messages: Interacts with YBX2.

89673:GHSR
gene id: 89673:GHSR
uniprot id: A0A6J2NCM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:EFNA1
gene id: 89673:EFNA1
uniprot id: A0A6J2KZY0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:LOC114490335
gene id: 89673:LOC114490335
uniprot id: A0A6J2KY14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:BCAS2
gene id: 89673:BCAS2
uniprot id: A0A6J2KZ95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPF27 family.
messages: Nucleus

89673:NR5A1
gene id: 89673:NR5A1
uniprot id: A0A6J2MB08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR5 subfamily.
messages: Nucleus

89673:BROX
gene id: 89673:BROX
uniprot id: A0A6J2N3H0
uniprot id: A0A6J2N9U5
names: Similarity
messages: Belongs to the BROX family.

89673:INTS3
gene id: 89673:INTS3
uniprot id: A0A6J2KW75
names: Similarity
messages: Belongs to the Integrator subunit 3 family.

89673:MYBL1
gene id: 89673:MYBL1
uniprot id: A0A7E6E659
uniprot id: A0A7E6E712
uniprot id: A0A7E6E7P1
uniprot id: A0A7E6E7T9
names: Subcellular Location Annotation
messages: Nucleus

89673:THBD
gene id: 89673:THBD
uniprot id: A0A6J2MLG5
names: Caution
names: Function
names: Subunit
messages: Interacts with ITGAL, ITGAM and ITGB2.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.

89673:ANK1
gene id: 89673:ANK1
uniprot id: A0A6J2MRQ9
uniprot id: A0A7E6CKL2
uniprot id: A0A7E6CKL6
uniprot id: A0A7E6CKM0
uniprot id: A0A7E6CKM3
uniprot id: A0A7E6CKP3
uniprot id: A0A7E6CMR3
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

89673:ITGA3
gene id: 89673:ITGA3
uniprot id: A0A7E6EEB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

89673:GUCA2A
gene id: 89673:GUCA2A
uniprot id: A0A6J2LLS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylin family.
messages: Secreted

89673:IGF2BP1
gene id: 89673:IGF2BP1
uniprot id: A0A6J2M6N8
uniprot id: A0A6J2M810
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM IMP/VICKZ family.
messages: Nucleus
messages: P-body
messages: Stress granule
messages: filopodium
messages: growth cone
messages: lamellipodium
messages: perinuclear region

89673:LOC114512112
gene id: 89673:LOC114512112
uniprot id: A0A7E6CX43
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: acrosome inner membrane

89673:CCDC86
gene id: 89673:CCDC86
uniprot id: A0A6J2LY34
names: Subcellular Location Annotation
messages: Nucleus

89673:NOS3
gene id: 89673:NOS3
uniprot id: A0A6J2MV82
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NOS family.
messages: Binds 1 FAD.
messages: Binds 1 FMN.
messages: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.

89673:SERP1
gene id: 89673:SERP1
uniprot id: A0A6J2KZJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.
messages: Membrane

89673:TRAM1
gene id: 89673:TRAM1
uniprot id: A0A6J2NHQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

89673:LOC114513247
gene id: 89673:LOC114513247
uniprot id: A0A6J2N6X3
uniprot id: A0A7E6D7I2
uniprot id: A0A7E6D7M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCAF family.
messages: Nucleus

89673:CRYZ
gene id: 89673:CRYZ
uniprot id: A0A6J2LNW6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

89673:LOC114489983
gene id: 89673:LOC114489983
uniprot id: A0A6J2KW87
names: Similarity
messages: Belongs to the actin family.

89673:MUC5AC
gene id: 89673:MUC5AC
uniprot id: A0A7E6E2Y5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114495078
gene id: 89673:LOC114495078
uniprot id: A0A6J2LE82
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

89673:IL1RAPL1
gene id: 89673:IL1RAPL1
uniprot id: A0A6J2MLB2
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

89673:LOC114508160
gene id: 89673:LOC114508160
uniprot id: A0A6J2MP60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114498863
gene id: 89673:LOC114498863
uniprot id: A0A6J2LXX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TBCCD1
gene id: 89673:TBCCD1
uniprot id: A0A6J2L3U8
uniprot id: A0A7E6D3V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCC family.
messages: centrosome
messages: spindle pole

89673:METTL26
gene id: 89673:METTL26
uniprot id: A0A6J2LX55
uniprot id: A0A6J2M134
uniprot id: A0A7E6DDP2
names: Similarity
messages: Belongs to the UPF0585 family.

89673:B4GALNT3
gene id: 89673:B4GALNT3
uniprot id: A0A6J2N8P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane
messages: Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.

89673:SPTB
gene id: 89673:SPTB
uniprot id: A0A6J2L6D4
names: Similarity
messages: Belongs to the spectrin family.

89673:POLH
gene id: 89673:POLH
uniprot id: A0A6J2LEQ5
names: Subcellular Location Annotation
messages: Nucleus

89673:SLC6A13
gene id: 89673:SLC6A13
uniprot id: A0A6J2N805
uniprot id: A0A7E6D552
uniprot id: A0A7E6D572
uniprot id: A0A7E6D5A3
uniprot id: A0A7E6D5U4
uniprot id: A0A7E6D812
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A13 subfamily.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane

89673:PON3
gene id: 89673:PON3
uniprot id: A0A6J2MUB5
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the paraoxonase family.
messages: Binds 2 calcium ions per subunit.
messages: Glycosylated.

89673:PRKG2
gene id: 89673:PRKG2
uniprot id: A0A6J2L8Q6
uniprot id: A0A6J2L954
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

89673:ADK
gene id: 89673:ADK
uniprot id: A0A6J2LIC3
uniprot id: A0A6J2LMU1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Monomer.
messages: Nucleus

89673:CA8
gene id: 89673:CA8
uniprot id: A0A6J2ND24
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

89673:DOCK3
gene id: 89673:DOCK3
uniprot id: A0A6J2M439
uniprot id: A0A7E6E3N2
uniprot id: A0A7E6E4A1
uniprot id: A0A7E6E550
uniprot id: A0A7E6E554
uniprot id: A0A7E6E596
names: Similarity
messages: Belongs to the DOCK family.

89673:LOC114499463
gene id: 89673:LOC114499463
uniprot id: A0A6J2LZP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GST superfamily. Pi family.
messages: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
messages: Cytoplasm
messages: Homodimer.
messages: Mitochondrion
messages: Nucleus

89673:INPP1
gene id: 89673:INPP1
uniprot id: A0A6J2LI03
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

89673:MEAF6
gene id: 89673:MEAF6
uniprot id: A0A6J2LPD5
uniprot id: A0A6J2LQK3
uniprot id: A0A7E6DRU3
uniprot id: A0A7E6DRY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EAF6 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
messages: Component of the NuA4 histone acetyltransferase complex. Component of the hbo1 complex. Component of the moz/morf complex.
messages: kinetochore
messages: nucleolus

89673:LOC114499025
gene id: 89673:LOC114499025
uniprot id: A0A6J2LSQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CPLX2
gene id: 89673:CPLX2
uniprot id: A0A6J2N2P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

89673:P2RX5
gene id: 89673:P2RX5
uniprot id: A0A7E6EC16
uniprot id: A0A7E6EC21
uniprot id: A0A7E6ECP1
uniprot id: A0A7E6ECU9
uniprot id: A0A7E6EDM8
uniprot id: A0A7E6EDV2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

89673:ORAI3
gene id: 89673:ORAI3
uniprot id: A0A6J2N8T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

89673:PWWP3B
gene id: 89673:PWWP3B
uniprot id: A0A6J2MMJ0
names: Similarity
messages: Belongs to the PWWP3A family.

89673:LOC114490315
gene id: 89673:LOC114490315
uniprot id: A0A6J2KXY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:DYNLRB2
gene id: 89673:DYNLRB2
uniprot id: A0A6J2KRH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
messages: Belongs to the GAMAD family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs); the composition seems to vary in respect to the IC, LIC and LC composition. The heavy chain homodimer serves as a scaffold for the probable homodimeric assembly of the respective non-catalytic subunits. The ICs and LICs bind directly to the HC dimer and the LCs assemble on the IC dimer.
messages: cytoskeleton

89673:ANKS3
gene id: 89673:ANKS3
uniprot id: A0A6J2M3I7
uniprot id: A0A7E6DBT6
uniprot id: A0A7E6DBT9
uniprot id: A0A7E6DC29
uniprot id: A0A7E6DC34
uniprot id: A0A7E6DC39
uniprot id: A0A7E6DCF7
uniprot id: A0A7E6DCG1
uniprot id: A0A7E6DCH2
uniprot id: A0A7E6DD05
uniprot id: A0A7E6DDL0
names: Function
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

89673:MRPL36
gene id: 89673:MRPL36
uniprot id: A0A6J2MBC8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

89673:ZSCAN25
gene id: 89673:ZSCAN25
uniprot id: A0A6J2L9S0
uniprot id: A0A7E6D8Z7
uniprot id: A0A7E6D9V8
names: Subcellular Location Annotation
messages: Nucleus

89673:CHST8
gene id: 89673:CHST8
uniprot id: A0A6J2N741
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

89673:IRX6
gene id: 89673:IRX6
uniprot id: A0A6J2KRM5
uniprot id: A0A7E6CLF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

89673:DEDD2
gene id: 89673:DEDD2
uniprot id: A0A6J2N2V8
names: Subcellular Location Annotation
messages: nucleolus

89673:UBA6
gene id: 89673:UBA6
uniprot id: A0A6J2L295
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

89673:EHD3
gene id: 89673:EHD3
uniprot id: A0A6J2LYK7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

89673:MBTD1
gene id: 89673:MBTD1
uniprot id: A0A6J2MC08
uniprot id: A0A6J2MEY9
uniprot id: A0A6J2MFG0
uniprot id: A0A7E6EF66
names: Subcellular Location Annotation
messages: Nucleus

89673:MACO1
gene id: 89673:MACO1
uniprot id: A0A6J2LJH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the macoilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane
messages: Plays a role in the regulation of neuronal activity.
messages: Rough endoplasmic reticulum membrane

89673:MOCS1
gene id: 89673:MOCS1
uniprot id: A0A6J2LDW5
uniprot id: A0A6J2LHQ1
names: Similarity
messages: In the C-terminal section; belongs to the MoaC family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. MoaA family.

89673:LARP7
gene id: 89673:LARP7
uniprot id: A0A6J2MBS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LARP7 family.
messages: nucleoplasm

89673:MEIS3
gene id: 89673:MEIS3
uniprot id: A0A6J2N0D7
uniprot id: A0A6J2N5U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

89673:ZNF687
gene id: 89673:ZNF687
uniprot id: A0A6J2KUR7
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

89673:VILL
gene id: 89673:VILL
uniprot id: A0A6J2M8B4
uniprot id: A0A7E6E5T7
names: Similarity
messages: Belongs to the villin/gelsolin family.

89673:FDPS
gene id: 89673:FDPS
uniprot id: A0A6J2KYR1
uniprot id: A0A7E6CX79
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

89673:PFN2
gene id: 89673:PFN2
uniprot id: A0A6J2KVA0
uniprot id: A0A6J2KVS5
uniprot id: A0A6J2KZ20
uniprot id: A0A6J2KZ31
uniprot id: A0A7E6D432
names: Similarity
messages: Belongs to the profilin family.

89673:YARS2
gene id: 89673:YARS2
uniprot id: A0A6J2NED4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

89673:ELF2
gene id: 89673:ELF2
uniprot id: A0A6J2MC43
uniprot id: A0A6J2MI48
uniprot id: A0A7E6E7Z9
uniprot id: A0A7E6E8V3
uniprot id: A0A7E6E9V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

89673:BEX3
gene id: 89673:BEX3
uniprot id: A0A7E6CZN4
names: Similarity
messages: Belongs to the BEX family.

89673:GSDMA
gene id: 89673:GSDMA
uniprot id: A0A6J2MG36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

89673:MTCL1
gene id: 89673:MTCL1
uniprot id: A0A6J2MQB8
uniprot id: A0A7E6CDX9
uniprot id: A0A7E6CDY0
uniprot id: A0A7E6CDY5
uniprot id: A0A7E6CE42
uniprot id: A0A7E6CE47
uniprot id: A0A7E6CEM9
uniprot id: A0A7E6CEN4
uniprot id: A0A7E6CG74
uniprot id: A0A7E6CG77
names: Similarity
messages: Belongs to the SOGA family.

89673:IP6K2
gene id: 89673:IP6K2
uniprot id: A0A6J2M179
uniprot id: A0A7E6E3W3
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

89673:LOC114503806
gene id: 89673:LOC114503806
uniprot id: A0A6J2MD34
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114493261
gene id: 89673:LOC114493261
uniprot id: A0A6J2L9V4
names: Function
names: Subcellular Location Annotation
messages: Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment.
messages: Secreted

89673:ZNF622
gene id: 89673:ZNF622
uniprot id: A0A6J2MSA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the REI1 family.
messages: Cytoplasm

89673:ADGRL4
gene id: 89673:ADGRL4
uniprot id: A0A7E6DTH3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:LOC114489791
gene id: 89673:LOC114489791
uniprot id: A0A7E6CR21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: microtubule organizing center

89673:HOXC10
gene id: 89673:HOXC10
uniprot id: A0A6J2N8J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

89673:CENPO
gene id: 89673:CENPO
uniprot id: A0A6J2M2Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-O/MCM21 family.
messages: Nucleus

89673:ID2
gene id: 89673:ID2
uniprot id: A0A6J2LVZ4
names: Subcellular Location Annotation
messages: Nucleus

89673:PGAM1
gene id: 89673:PGAM1
uniprot id: A0A6J2LNN0
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

89673:GPAT4
gene id: 89673:GPAT4
uniprot id: A0A6J2MRY9
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

89673:PDLIM1
gene id: 89673:PDLIM1
uniprot id: A0A6J2LUR7
names: Subcellular Location Annotation
messages: Z line

89673:TARS2
gene id: 89673:TARS2
uniprot id: A0A6J2KTV5
uniprot id: A0A6J2KUF9
uniprot id: A0A7E6D003
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

89673:TMEM65
gene id: 89673:TMEM65
uniprot id: A0A6J2NCM7
uniprot id: A0A7E6E896
names: Subcellular Location Annotation
messages: Membrane

89673:RPS4X
gene id: 89673:RPS4X
uniprot id: A0A6J2MGI9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

89673:CD8B
gene id: 89673:CD8B
uniprot id: A0A6J2LR37
names: Subcellular Location Annotation
messages: Membrane

89673:TMC7
gene id: 89673:TMC7
uniprot id: A0A6J2MX37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

89673:GPR179
gene id: 89673:GPR179
uniprot id: A0A6J2MGT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

89673:AMOTL2
gene id: 89673:AMOTL2
uniprot id: A0A6J2M1T2
uniprot id: A0A6J2M6V5
names: Similarity
messages: Belongs to the angiomotin family.

89673:NANOS2
gene id: 89673:NANOS2
uniprot id: A0A6J2N1Y6
names: Similarity
messages: Belongs to the nanos family.

89673:LOC114490986
gene id: 89673:LOC114490986
uniprot id: A0A6J2L0F5
uniprot id: A0A6J2L216
uniprot id: A0A6J2L409
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

89673:LOC114508185
gene id: 89673:LOC114508185
uniprot id: A0A6J2MR59
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

89673:SLC35B2
gene id: 89673:SLC35B2
uniprot id: A0A6J2LDV6
uniprot id: A0A7E6DM36
uniprot id: A0A7E6DM75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

89673:RDH13
gene id: 89673:RDH13
uniprot id: A0A6J2N195
uniprot id: A0A7E6CNQ8
uniprot id: A0A7E6CR52
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

89673:GPR61
gene id: 89673:GPR61
uniprot id: A0A6J2KU69
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:KCNH1
gene id: 89673:KCNH1
uniprot id: A0A6J2N2A5
uniprot id: A0A6J2N3Z0
names: Subcellular Location Annotation
messages: Membrane

89673:RPE
gene id: 89673:RPE
uniprot id: A0A6J2LI16
uniprot id: A0A7E6DIH9
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

89673:GLYATL3
gene id: 89673:GLYATL3
uniprot id: A0A6J2LKN0
uniprot id: A0A7E6DM78
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

89673:SMARCA5
gene id: 89673:SMARCA5
uniprot id: A0A6J2MA34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

89673:SMC5
gene id: 89673:SMC5
uniprot id: A0A6J2LCX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC5 subfamily.
messages: Chromosome
messages: Nucleus

89673:APOA4
gene id: 89673:APOA4
uniprot id: A0A6J2LXT8
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

89673:AVPR1B
gene id: 89673:AVPR1B
uniprot id: A0A6J2N4M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.

89673:IRAK4
gene id: 89673:IRAK4
uniprot id: A0A6J2NH27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with MYD88 and IRAK2 to form a ternary complex called the Myddosome.
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
messages: Cytoplasm
messages: Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens.

89673:SEC23B
gene id: 89673:SEC23B
uniprot id: A0A6J2MJA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

89673:LOC114506713
gene id: 89673:LOC114506713
uniprot id: A0A6J2MQS9
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

89673:KIF13B
gene id: 89673:KIF13B
uniprot id: A0A7E6E977
uniprot id: A0A7E6E9E7
uniprot id: A0A7E6EA21
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

89673:MVD
gene id: 89673:MVD
uniprot id: A0A6J2KQV4
names: Function
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.
messages: Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis.

89673:SST
gene id: 89673:SST
uniprot id: A0A6J2KZR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted

89673:DNASE2B
gene id: 89673:DNASE2B
uniprot id: A0A6J2LRG4
uniprot id: A0A7E6DSR1
uniprot id: A0A7E6DTC9
names: Similarity
messages: Belongs to the DNase II family.

89673:GDA
gene id: 89673:GDA
uniprot id: A0A6J2LXK9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

89673:LOC114496976
gene id: 89673:LOC114496976
uniprot id: A0A7E6DXC6
names: Similarity
messages: Belongs to the SUI1 family.

89673:DNTT
gene id: 89673:DNTT
uniprot id: A0A6J2LQ60
uniprot id: A0A6J2LU94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Nucleus
messages: Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator.

89673:SAXO2
gene id: 89673:SAXO2
uniprot id: A0A6J2KY66
names: Similarity
messages: Belongs to the FAM154 family.

89673:PRKG1
gene id: 89673:PRKG1
uniprot id: A0A6J2LJA5
uniprot id: A0A6J2LML2
uniprot id: A0A7E6DW89
uniprot id: A0A7E6DX20
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

89673:EPHB4
gene id: 89673:EPHB4
uniprot id: A0A6J2L9V7
uniprot id: A0A7E6DBB4
names: Subcellular Location Annotation
messages: Membrane

89673:COG3
gene id: 89673:COG3
uniprot id: A0A6J2MW51
names: Function
names: Similarity
messages: Belongs to the COG3 family.
messages: Involved in ER-Golgi transport.

89673:PRICKLE2
gene id: 89673:PRICKLE2
uniprot id: A0A6J2M1B7
uniprot id: A0A6J2M3K6
uniprot id: A0A7E6E6F6
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

89673:COL4A3
gene id: 89673:COL4A3
uniprot id: A0A6J2LBP7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

89673:LGMN
gene id: 89673:LGMN
uniprot id: A0A6J2L6W8
names: Similarity
messages: Belongs to the peptidase C13 family.

89673:APEX2
gene id: 89673:APEX2
uniprot id: A0A6J2ML61
uniprot id: A0A7E6D110
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Cytoplasm
messages: Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
messages: Mitochondrion
messages: Nucleus
messages: Probably binds two magnesium or manganese ions per subunit.

89673:LPIN2
gene id: 89673:LPIN2
uniprot id: A0A7E6CDY6
names: Similarity
messages: Belongs to the lipin family.

89673:ZNF277
gene id: 89673:ZNF277
uniprot id: A0A6J2MQH6
names: Similarity
messages: Belongs to the ZNF277 family.

89673:SERPINB2
gene id: 89673:SERPINB2
uniprot id: A0A6J2MS59
uniprot id: A0A7E6CGH6
names: Similarity
messages: Belongs to the serpin family.

89673:VPS37A
gene id: 89673:VPS37A
uniprot id: A0A6J2MRG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

89673:LRP8
gene id: 89673:LRP8
uniprot id: A0A7E6DS12
uniprot id: A0A7E6DS18
uniprot id: A0A7E6DS25
uniprot id: A0A7E6DS35
uniprot id: A0A7E6DS42
uniprot id: A0A7E6DS49
uniprot id: A0A7E6DSP0
uniprot id: A0A7E6DSP5
uniprot id: A0A7E6DSQ1
uniprot id: A0A7E6DST6
uniprot id: A0A7E6DSU3
uniprot id: A0A7E6DSV0
uniprot id: A0A7E6DT74
uniprot id: A0A7E6DT79
uniprot id: A0A7E6DT84
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:TMEM59
gene id: 89673:TMEM59
uniprot id: A0A6J2LMH9
uniprot id: A0A6J2LSV2
uniprot id: A0A6J2LSX5
uniprot id: A0A7E6DSX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM59 family.
messages: Golgi apparatus membrane
messages: Membrane

89673:LOC114503017
gene id: 89673:LOC114503017
uniprot id: A0A6J2M856
uniprot id: A0A6J2MDH4
names: Similarity
messages: Belongs to the intermediate filament family.

89673:DTNBP1
gene id: 89673:DTNBP1
uniprot id: A0A6J2LKI5
uniprot id: A0A7E6DT96
names: Similarity
messages: Belongs to the dysbindin family.

89673:ALAD
gene id: 89673:ALAD
uniprot id: A0A6J2MQK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer; active form. Homohexamer; low activity form.

89673:FOXN3
gene id: 89673:FOXN3
uniprot id: A0A6J2L4D5
uniprot id: A0A6J2L6F8
uniprot id: A0A7E6CPY0
names: Function
names: Subcellular Location Annotation
messages: Acts as a transcriptional repressor. May be involved in DNA damage-inducible cell cycle arrests (checkpoints).
messages: Nucleus

89673:ITPKC
gene id: 89673:ITPKC
uniprot id: A0A6J2N0V6
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

89673:ATL2
gene id: 89673:ATL2
uniprot id: A0A6J2M037
uniprot id: A0A6J2M254
uniprot id: A0A6J2M5L7
uniprot id: A0A7E6DXK0
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

89673:TTC21A
gene id: 89673:TTC21A
uniprot id: A0A6J2M7J9
names: Similarity
messages: Belongs to the TTC21 family.

89673:SLC9A1
gene id: 89673:SLC9A1
uniprot id: A0A6J2LNM4
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane

89673:COQ5
gene id: 89673:COQ5
uniprot id: A0A6J2N0Z5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
messages: Mitochondrion inner membrane

89673:TMEM17
gene id: 89673:TMEM17
uniprot id: A0A6J2LYN4
uniprot id: A0A7E6DYG5
names: Subcellular Location Annotation
messages: Membrane

89673:NDUFB8
gene id: 89673:NDUFB8
uniprot id: A0A6J2LJB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB8 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

89673:TPP1
gene id: 89673:TPP1
uniprot id: A0A6J2M0V2
uniprot id: A0A6J2M4B2
names: Cofactor
messages: Binds 1 Ca(2+) ion per subunit.

89673:MFSD3
gene id: 89673:MFSD3
uniprot id: A0A6J2NCM9
names: Subcellular Location Annotation
messages: Membrane

89673:IDE
gene id: 89673:IDE
uniprot id: A0A6J2LHM6
uniprot id: A0A6J2LIV0
uniprot id: A0A7E6DUN4
uniprot id: A0A7E6DVV6
names: Similarity
messages: Belongs to the peptidase M16 family.

89673:LOC114499058
gene id: 89673:LOC114499058
uniprot id: A0A7E6E3L1
names: Subcellular Location Annotation
messages: Membrane

89673:CHPF2
gene id: 89673:CHPF2
uniprot id: A0A6J2MQX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

89673:CD5
gene id: 89673:CD5
uniprot id: A0A7E6E4H9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:GLRX
gene id: 89673:GLRX
uniprot id: A0A6J2M946
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

89673:NCEH1
gene id: 89673:NCEH1
uniprot id: A0A6J2L3R9
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

89673:SLC12A5
gene id: 89673:SLC12A5
uniprot id: A0A6J2MJ37
uniprot id: A0A6J2MQ74
uniprot id: A0A7E6CFN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

89673:LOC118499330
gene id: 89673:LOC118499330
uniprot id: A0A7E6D9H1
names: Similarity
messages: Belongs to the NUT family.

89673:LOC114489500
gene id: 89673:LOC114489500
uniprot id: A0A7E6CZJ1
names: Subcellular Location Annotation
messages: Nucleus

89673:MRPL13
gene id: 89673:MRPL13
uniprot id: A0A6J2NB66
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

89673:LOC114491310
gene id: 89673:LOC114491310
uniprot id: A0A7E6DQT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

89673:LOC114498859
gene id: 89673:LOC114498859
uniprot id: A0A7E6E3D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ATPase B chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion
messages: Mitochondrion inner membrane

89673:LOC114505000
gene id: 89673:LOC114505000
uniprot id: A0A7E6CZV1
names: Subcellular Location Annotation
messages: Mitochondrion

89673:IL17RE
gene id: 89673:IL17RE
uniprot id: A0A7E6E571
uniprot id: A0A7E6E5T2
uniprot id: A0A7E6E5X8
uniprot id: A0A7E6E6Q6
uniprot id: A0A7E6E6U8
uniprot id: A0A7E6E6V3
names: Subcellular Location Annotation
messages: Membrane

89673:ABCG8
gene id: 89673:ABCG8
uniprot id: A0A6J2M2Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

89673:POLR2H
gene id: 89673:POLR2H
uniprot id: A0A6J2KYK5
uniprot id: A0A6J2L098
names: Function
names: Similarity
messages: Belongs to the eukaryotic RPB8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.

89673:LOC114505646
gene id: 89673:LOC114505646
uniprot id: A0A7E6D0Q0
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

89673:SCD
gene id: 89673:SCD
uniprot id: A0A6J2LMT9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

89673:GRHL3
gene id: 89673:GRHL3
uniprot id: A0A6J2LS23
names: Subcellular Location Annotation
messages: Nucleus

89673:TRMT13
gene id: 89673:TRMT13
uniprot id: A0A6J2KZU5
uniprot id: A0A7E6CXD1
uniprot id: A0A7E6CZY9
names: Function
names: Similarity
messages: Belongs to the methyltransferase TRM13 family.
messages: tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).

89673:LSM12
gene id: 89673:LSM12
uniprot id: A0A6J2MAY4
names: Similarity
messages: Belongs to the LSM12 family.

89673:LOC114492418
gene id: 89673:LOC114492418
uniprot id: A0A6J2L2A5
uniprot id: A0A6J2L2Y0
uniprot id: A0A6J2L471
uniprot id: A0A6J2L577
uniprot id: A0A6J2L987
uniprot id: A0A7E6DP47
uniprot id: A0A7E6DP48
uniprot id: A0A7E6DP52
uniprot id: A0A7E6DPN8
uniprot id: A0A7E6DPU2
uniprot id: A0A7E6DPU7
uniprot id: A0A7E6DPV2
uniprot id: A0A7E6DQ76
uniprot id: A0A7E6DQ81
names: Similarity
messages: Belongs to the aldo/keto reductase family.

89673:EXOG
gene id: 89673:EXOG
uniprot id: A0A6J2M2R9
uniprot id: A0A6J2M489
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

89673:NFKB2
gene id: 89673:NFKB2
uniprot id: A0A6J2LL24
uniprot id: A0A6J2LNP4
uniprot id: A0A7E6DVA6
uniprot id: A0A7E6DVR4
uniprot id: A0A7E6DWJ4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

89673:TFAP2D
gene id: 89673:TFAP2D
uniprot id: A0A6J2LH96
uniprot id: A0A7E6DLW4
names: Similarity
messages: Belongs to the AP-2 family.

89673:BCL7B
gene id: 89673:BCL7B
uniprot id: A0A6J2M008
names: Similarity
messages: Belongs to the BCL7 family.

89673:STPG1
gene id: 89673:STPG1
uniprot id: A0A6J2LVQ8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

89673:HNRNPF
gene id: 89673:HNRNPF
uniprot id: A0A6J2LMD5
names: Subcellular Location Annotation
messages: nucleoplasm

89673:GRIK4
gene id: 89673:GRIK4
uniprot id: A0A6J2MV81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

89673:ETV3L
gene id: 89673:ETV3L
uniprot id: A0A7E6CX97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

89673:SDR16C5
gene id: 89673:SDR16C5
uniprot id: A0A6J2NDG7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

89673:LGI2
gene id: 89673:LGI2
uniprot id: A0A6J2LB20
names: Subcellular Location Annotation
messages: Secreted

89673:LOC114489256
gene id: 89673:LOC114489256
uniprot id: A0A6J2KYF0
names: Similarity
messages: Belongs to the 3-beta-HSD family.

89673:RFC4
gene id: 89673:RFC4
uniprot id: A0A6J2L3Q7
names: Similarity
messages: Belongs to the activator 1 small subunits family.

89673:LOC114514180
gene id: 89673:LOC114514180
uniprot id: A0A7E6D6B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:FBLL1
gene id: 89673:FBLL1
uniprot id: A0A6J2N1D0
names: Similarity
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.

89673:CASP8
gene id: 89673:CASP8
uniprot id: A0A7E6DIS3
uniprot id: A0A7E6DJ04
uniprot id: A0A7E6DJ58
names: Similarity
messages: Belongs to the peptidase C14A family.

89673:ENDOU
gene id: 89673:ENDOU
uniprot id: A0A7E6D7M3
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

89673:PPP2R2C
gene id: 89673:PPP2R2C
uniprot id: A0A6J2L655
uniprot id: A0A7E6D5I8
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

89673:ERBB4
gene id: 89673:ERBB4
uniprot id: A0A6J2LDT9
uniprot id: A0A7E6DI92
uniprot id: A0A7E6DIB7
uniprot id: A0A7E6DIG8
uniprot id: A0A7E6DIH1
uniprot id: A0A7E6DIL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

89673:C8G
gene id: 89673:C8G
uniprot id: A0A7E6DH14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

89673:LOC114496142
gene id: 89673:LOC114496142
uniprot id: A0A7E6DPY2
names: Similarity
messages: Belongs to the intermediate filament family.

89673:STN1
gene id: 89673:STN1
uniprot id: A0A6J2LPH8
uniprot id: A0A7E6DV93
uniprot id: A0A7E6DVE0
uniprot id: A0A7E6DVV1
uniprot id: A0A7E6DVV4
uniprot id: A0A7E6DW77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the STN1 family.
messages: Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.
messages: Component of the CST complex.
messages: Nucleus
messages: telomere

89673:KCNK15
gene id: 89673:KCNK15
uniprot id: A0A6J2MQ08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

89673:LRRFIP2
gene id: 89673:LRRFIP2
uniprot id: A0A6J2M2M4
uniprot id: A0A6J2M4W4
uniprot id: A0A6J2M7N7
uniprot id: A0A6J2M7P2
uniprot id: A0A6J2M8A0
uniprot id: A0A6J2M8A5
uniprot id: A0A7E6E4B2
uniprot id: A0A7E6E4B6
uniprot id: A0A7E6E4W4
uniprot id: A0A7E6E4W8
uniprot id: A0A7E6E505
uniprot id: A0A7E6E511
uniprot id: A0A7E6E5U2
uniprot id: A0A7E6E5U7
uniprot id: A0A7E6E604
uniprot id: A0A7E6E610
names: Similarity
messages: Belongs to the LRRFIP family.

89673:ADSS1
gene id: 89673:ADSS1
uniprot id: A0A6J2LAJ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

89673:ORAI1
gene id: 89673:ORAI1
uniprot id: A0A6J2MV43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

89673:SLC37A4
gene id: 89673:SLC37A4
uniprot id: A0A6J2M1C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

89673:LOC114502885
gene id: 89673:LOC114502885
uniprot id: A0A6J2M8T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COA3 family.
messages: Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.
messages: Core component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly.
messages: Membrane
messages: Required for assembly of cytochrome c oxidase (complex IV).

89673:BPI
gene id: 89673:BPI
uniprot id: A0A6J2MLV1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

89673:BEX4
gene id: 89673:BEX4
uniprot id: A0A6J2MH48
names: Similarity
messages: Belongs to the BEX family.

89673:LOC114500512
gene id: 89673:LOC114500512
uniprot id: A0A6J2M0A8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:FMNL3
gene id: 89673:FMNL3
uniprot id: A0A6J2N6I0
uniprot id: A0A6J2N877
uniprot id: A0A6J2N8K4
uniprot id: A0A6J2NDS7
uniprot id: A0A7E6D6Q5
uniprot id: A0A7E6D6T0
uniprot id: A0A7E6D9M7
names: Similarity
messages: Belongs to the formin homology family.

89673:GBX1
gene id: 89673:GBX1
uniprot id: A0A6J2MPA5
names: Subcellular Location Annotation
messages: Nucleus

89673:GSTK1
gene id: 89673:GSTK1
uniprot id: A0A6J2MUT7
names: Similarity
messages: Belongs to the GST superfamily. Kappa family.

89673:KCNJ11
gene id: 89673:KCNJ11
uniprot id: A0A6J2M329
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ11 subfamily.
messages: Membrane

89673:DLST
gene id: 89673:DLST
uniprot id: A0A6J2L746
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Mitochondrion matrix

89673:ATP6AP2
gene id: 89673:ATP6AP2
uniprot id: A0A6J2MGQ2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Lysosome membrane
messages: Membrane
messages: autophagosome membrane
messages: clathrin-coated vesicle membrane
messages: dendritic spine membrane
messages: synaptic vesicle membrane

89673:GSS
gene id: 89673:GSS
uniprot id: A0A6J2MKT8
uniprot id: A0A6J2MMK8
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic GSH synthase family.
messages: Binds 1 Mg(2+) ion per subunit.

89673:MRPS2
gene id: 89673:MRPS2
uniprot id: A0A7E6DCP8
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

89673:LOC114488950
gene id: 89673:LOC114488950
uniprot id: A0A7E6CYA6
names: Similarity
messages: Belongs to the GST superfamily. Mu family.

89673:TPRA1
gene id: 89673:TPRA1
uniprot id: A0A6J2MM59
uniprot id: A0A7E6CE73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0359 family.
messages: Membrane

89673:NKX1-2
gene id: 89673:NKX1-2
uniprot id: A0A6J2LI87
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114513220
gene id: 89673:LOC114513220
uniprot id: A0A6J2N8W6
names: Subcellular Location Annotation
messages: Membrane

89673:INO80C
gene id: 89673:INO80C
uniprot id: A0A6J2MKI2
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC118498503
gene id: 89673:LOC118498503
uniprot id: A0A7E6D2D8
names: Similarity
messages: Belongs to the learning-associated protein family.

89673:RRP1
gene id: 89673:RRP1
uniprot id: A0A6J2KZF8
names: Similarity
messages: Belongs to the RRP1 family.

89673:LACC1
gene id: 89673:LACC1
uniprot id: A0A6J2MSW6
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

89673:YBEY
gene id: 89673:YBEY
uniprot id: A0A6J2KZA0
uniprot id: A0A7E6D310
names: Similarity
messages: Belongs to the endoribonuclease YbeY family.

89673:LOC114490201
gene id: 89673:LOC114490201
uniprot id: A0A6J2KWY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ZC3H12C
gene id: 89673:ZC3H12C
uniprot id: A0A6J2LVQ6
uniprot id: A0A7E6DZ70
uniprot id: A0A7E6E036
names: Similarity
messages: Belongs to the ZC3H12 family.

89673:LOC114498984
gene id: 89673:LOC114498984
uniprot id: A0A7E6E3K7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

89673:LOC114500937
gene id: 89673:LOC114500937
uniprot id: A0A6J2M5B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

89673:PTGDR2
gene id: 89673:PTGDR2
uniprot id: A0A6J2LZ27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

89673:CCM2L
gene id: 89673:CCM2L
uniprot id: A0A6J2MJD8
uniprot id: A0A6J2MLH5
uniprot id: A0A7E6CF17
uniprot id: A0A7E6CH82
names: Similarity
messages: Belongs to the CCM2 family.

89673:SNX3
gene id: 89673:SNX3
uniprot id: A0A6J2LFK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome
messages: Endosome
messages: phagosome

89673:RBM48
gene id: 89673:RBM48
uniprot id: A0A6J2MP28
names: Function
names: Similarity
names: Subunit
messages: As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.
messages: Belongs to the RBM48 family.
messages: Component of the minor spliceosome. Within this complex, interacts with ARMC7 and PRPF8/PRP8.

89673:LOC114489470
gene id: 89673:LOC114489470
uniprot id: A0A7E6CXZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

89673:POLR2J
gene id: 89673:POLR2J
uniprot id: A0A6J2MBZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft.
messages: Nucleus

89673:SLC17A5
gene id: 89673:SLC17A5
uniprot id: A0A6J2LE97
uniprot id: A0A7E6DM92
uniprot id: A0A7E6DN20
names: Subcellular Location Annotation
messages: Membrane

89673:LIPI
gene id: 89673:LIPI
uniprot id: A0A6J2L091
uniprot id: A0A7E6D3L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

89673:MRM1
gene id: 89673:MRM1
uniprot id: A0A6J2M8J8
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

89673:SMARCA1
gene id: 89673:SMARCA1
uniprot id: A0A6J2MF52
uniprot id: A0A6J2MID3
uniprot id: A0A6J2MJ20
uniprot id: A0A7E6D0H3
uniprot id: A0A7E6D0J3
uniprot id: A0A7E6D0Q6
uniprot id: A0A7E6D1E7
uniprot id: A0A7E6D3B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

89673:RAB38
gene id: 89673:RAB38
uniprot id: A0A6J2LW05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

89673:LOC114489529
gene id: 89673:LOC114489529
uniprot id: A0A6J2KWT5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:ERGIC2
gene id: 89673:ERGIC2
uniprot id: A0A6J2N7W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

89673:LOC114512289
gene id: 89673:LOC114512289
uniprot id: A0A6J2N3C6
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

89673:TLCD3B
gene id: 89673:TLCD3B
uniprot id: A0A6J2MJF3
names: Subcellular Location Annotation
messages: Membrane

89673:SCN11A
gene id: 89673:SCN11A
uniprot id: A0A7E6E4Y5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

89673:PTCD2
gene id: 89673:PTCD2
uniprot id: A0A7E6DAC1
uniprot id: A0A7E6DBH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTCD2 family.
messages: Mitochondrion

89673:ROS1
gene id: 89673:ROS1
uniprot id: A0A7E6DNF0
uniprot id: A0A7E6DNH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

89673:EIF2B4
gene id: 89673:EIF2B4
uniprot id: A0A6J2LY26
uniprot id: A0A6J2LZ57
uniprot id: A0A6J2M016
uniprot id: A0A6J2M336
uniprot id: A0A6J2M3J3
uniprot id: A0A7E6DY50
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

89673:LOC114504538
gene id: 89673:LOC114504538
uniprot id: A0A6J2MF75
names: Similarity
messages: Belongs to the IAP family.

89673:LOC114489528
gene id: 89673:LOC114489528
uniprot id: A0A6J2KWT5
uniprot id: A0A6J2L138
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:LCK
gene id: 89673:LCK
uniprot id: A0A6J2LTN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

89673:LOC114508134
gene id: 89673:LOC114508134
uniprot id: A0A6J2MR12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114488691
gene id: 89673:LOC114488691
uniprot id: A0A6J2KW20
uniprot id: A0A7E6CQ02
names: Similarity
messages: Belongs to the CEMIP family.

89673:PTPN11
gene id: 89673:PTPN11
uniprot id: A0A6J2MWG1
uniprot id: A0A7E6CU71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm

89673:LOC114492481
gene id: 89673:LOC114492481
uniprot id: A0A6J2L6S8
names: Subcellular Location Annotation
messages: Nucleus

89673:HOMER3
gene id: 89673:HOMER3
uniprot id: A0A6J2M6F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

89673:NEIL1
gene id: 89673:NEIL1
uniprot id: A0A6J2L5G2
uniprot id: A0A7E6DWN4
uniprot id: A0A7E6DWZ7
uniprot id: A0A7E6DX21
names: Similarity
messages: Belongs to the FPG family.

89673:E2F4
gene id: 89673:E2F4
uniprot id: A0A6J2KR49
uniprot id: A0A7E6CLT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

89673:TLR4
gene id: 89673:TLR4
uniprot id: A0A6J2N586
uniprot id: A0A7E6DG53
uniprot id: A0A7E6DGC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

89673:SNX33
gene id: 89673:SNX33
uniprot id: A0A6J2L2G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

89673:BAZ1B
gene id: 89673:BAZ1B
uniprot id: A0A6J2LQR1
names: Subcellular Location Annotation
messages: Nucleus

89673:SFT2D2
gene id: 89673:SFT2D2
uniprot id: A0A6J2N2V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

89673:HCFC1
gene id: 89673:HCFC1
uniprot id: A0A6J2MG56
uniprot id: A0A6J2MGD7
uniprot id: A0A6J2MJM4
uniprot id: A0A7E6CZU9
uniprot id: A0A7E6CZV2
uniprot id: A0A7E6D2K3
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114514157
gene id: 89673:LOC114514157
uniprot id: A0A6J2N9V2
uniprot id: A0A7E6D7C3
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

89673:XRN2
gene id: 89673:XRN2
uniprot id: A0A6J2MJ94
uniprot id: A0A7E6CED8
names: Function
names: Similarity
messages: Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
messages: Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.

89673:TRIP13
gene id: 89673:TRIP13
uniprot id: A0A6J2LVW5
uniprot id: A0A7E6DA75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AAA ATPase family. PCH2 subfamily.
messages: Nucleus
messages: Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways.
messages: Specifically interacts with the ligand binding domain of the thyroid receptor (TR). This interaction does not require the presence of thyroid hormone for its interaction. Interacts with proteasome subunit PSMA8; to participate in meiosis progression during spermatogenesis.

89673:CPA1
gene id: 89673:CPA1
uniprot id: A0A6J2MQG3
names: Similarity
messages: Belongs to the peptidase M14 family.

89673:CENPQ
gene id: 89673:CENPQ
uniprot id: A0A7E6DLV3
uniprot id: A0A7E6DM83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-Q/OKP1 family.
messages: Nucleus

89673:C7H8orf37
gene id: 89673:C7H8orf37
uniprot id: A0A6J2NCR1
uniprot id: A0A7E6E6G3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in photoreceptor outer segment disk morphogenesis.
messages: Photoreceptor inner segment

89673:ISM1
gene id: 89673:ISM1
uniprot id: A0A6J2MS16
names: Similarity
messages: Belongs to the isthmin family.

89673:LOC114504778
gene id: 89673:LOC114504778
uniprot id: A0A6J2MKE5
names: Similarity
messages: Belongs to the SPIN/STSY family.

89673:ABO
gene id: 89673:ABO
uniprot id: A0A6J2MY88
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Membrane

89673:SLC2A2
gene id: 89673:SLC2A2
uniprot id: A0A6J2NJ90
uniprot id: A0A7E6D2Y0
uniprot id: A0A7E6D3I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane
messages: Membrane

89673:KIDINS220
gene id: 89673:KIDINS220
uniprot id: A0A6J2LZI1
uniprot id: A0A6J2M0T4
uniprot id: A0A6J2M4K5
uniprot id: A0A6J2M4L0
uniprot id: A0A6J2M544
uniprot id: A0A7E6DXA1
names: Function
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

89673:FPGS
gene id: 89673:FPGS
uniprot id: A0A6J2LXH8
uniprot id: A0A7E6DGK8
uniprot id: A0A7E6DGQ3
names: Cofactor
names: Function
names: Similarity
messages: A monovalent cation.
messages: Belongs to the folylpolyglutamate synthase family.
messages: Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis.

89673:KPNA3
gene id: 89673:KPNA3
uniprot id: A0A7E6CM37
names: Function
names: Similarity
messages: Belongs to the importin alpha family.
messages: Functions in nuclear protein import.

89673:SLC12A3
gene id: 89673:SLC12A3
uniprot id: A0A6J2KQ91
uniprot id: A0A7E6CNM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

89673:LITAF
gene id: 89673:LITAF
uniprot id: A0A6J2N269
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

89673:SLC25A11
gene id: 89673:SLC25A11
uniprot id: A0A6J2NDU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

89673:SCN2A
gene id: 89673:SCN2A
uniprot id: A0A6J2L957
uniprot id: A0A7E6DJJ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

89673:ARPC4
gene id: 89673:ARPC4
uniprot id: A0A6J2M6W3
uniprot id: A0A7E6E6Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARPC4 family.
messages: Cell projection
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
messages: cytoskeleton

89673:DNMT3B
gene id: 89673:DNMT3B
uniprot id: A0A6J2MM51
uniprot id: A0A7E6CF34
uniprot id: A0A7E6CF86
uniprot id: A0A7E6CF92
uniprot id: A0A7E6CFQ3
uniprot id: A0A7E6CH96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

89673:LOC114500323
gene id: 89673:LOC114500323
uniprot id: A0A6J2LZM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ATP2A2
gene id: 89673:ATP2A2
uniprot id: A0A6J2MW64
uniprot id: A0A6J2N2D4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

89673:LOC114488894
gene id: 89673:LOC114488894
uniprot id: A0A6J2KVB6
uniprot id: A0A7E6CXH7
uniprot id: A0A7E6CY02
names: Similarity
messages: Belongs to the arrestin family.

89673:KIF21A
gene id: 89673:KIF21A
uniprot id: A0A6J2NG24
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

89673:BORA
gene id: 89673:BORA
uniprot id: A0A7E6CJX3
uniprot id: A0A7E6CJZ6
names: Similarity
messages: Belongs to the BORA family.

89673:PPCS
gene id: 89673:PPCS
uniprot id: A0A6J2LL35
uniprot id: A0A7E6DRB2
uniprot id: A0A7E6DRE7
uniprot id: A0A7E6DS15
uniprot id: A0A7E6DSJ2
names: Similarity
messages: Belongs to the PPC synthetase family.

89673:KCNE3
gene id: 89673:KCNE3
uniprot id: A0A6J2LYK6
names: Similarity
messages: Belongs to the potassium channel KCNE family.

89673:LOC114488380
gene id: 89673:LOC114488380
uniprot id: A0A7E6CM38
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL28 family.

89673:LOC114500257
gene id: 89673:LOC114500257
uniprot id: A0A6J2M3S5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ENTPD2
gene id: 89673:ENTPD2
uniprot id: A0A6J2MZZ6
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

89673:ST8SIA1
gene id: 89673:ST8SIA1
uniprot id: A0A6J2N724
uniprot id: A0A7E6D7F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

89673:CRAT
gene id: 89673:CRAT
uniprot id: A0A6J2LMN6
uniprot id: A0A6J2LNQ2
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

89673:SMG6
gene id: 89673:SMG6
uniprot id: A0A6J2M4A0
uniprot id: A0A6J2M6E2
uniprot id: A0A6J2M9W2
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini.
messages: Plays a role in nonsense-mediated mRNA decay.
messages: The PINc domain confers endonuclease activity and is expected to bind the catalytic metal ion.
messages: cytosol
messages: nucleolus
messages: telomere

89673:LOC114493838
gene id: 89673:LOC114493838
uniprot id: A0A6J2L9F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

89673:PYGL
gene id: 89673:PYGL
uniprot id: A0A6J2L1R3
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

89673:LOC114490215
gene id: 89673:LOC114490215
uniprot id: A0A7E6DL90
uniprot id: A0A7E6DL94
uniprot id: A0A7E6DL95
uniprot id: A0A7E6DLM5
uniprot id: A0A7E6DLQ3
uniprot id: A0A7E6DLQ9
uniprot id: A0A7E6DM01
names: Similarity
messages: Belongs to the MHC class I family.

89673:LOC118498547
gene id: 89673:LOC118498547
uniprot id: A0A7E6D0F4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

89673:LOC114496168
gene id: 89673:LOC114496168
uniprot id: A0A7E6DEQ7
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

89673:SUPT5H
gene id: 89673:SUPT5H
uniprot id: A0A6J2N362
uniprot id: A0A6J2N7T7
uniprot id: A0A7E6CLD8
uniprot id: A0A7E6CLE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT5 family.
messages: Nucleus

89673:EIF4E
gene id: 89673:EIF4E
uniprot id: A0A6J2L7V1
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

89673:LAMB1
gene id: 89673:LAMB1
uniprot id: A0A6J2MNB7
uniprot id: A0A7E6CIJ3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

89673:LOC114506484
gene id: 89673:LOC114506484
uniprot id: A0A6J2MPW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

89673:LOC114500726
gene id: 89673:LOC114500726
uniprot id: A0A6J2M4X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114490027
gene id: 89673:LOC114490027
uniprot id: A0A6J2KWD1
names: Function
names: Subunit
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

89673:TRIM36
gene id: 89673:TRIM36
uniprot id: A0A6J2MSX1
uniprot id: A0A6J2MXT6
uniprot id: A0A7E6DB75
uniprot id: A0A7E6DCA1
uniprot id: A0A7E6DDE6
names: Subcellular Location Annotation
messages: cytoskeleton

89673:MATK
gene id: 89673:MATK
uniprot id: A0A6J2M9V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

89673:GPT2
gene id: 89673:GPT2
uniprot id: A0A6J2KUZ6
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

89673:SPTSSB
gene id: 89673:SPTSSB
uniprot id: A0A7E6D2S5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:FOXF1
gene id: 89673:FOXF1
uniprot id: A0A6J2KQG9
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114507856
gene id: 89673:LOC114507856
uniprot id: A0A6J2MNB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SSU72
gene id: 89673:SSU72
uniprot id: A0A6J2LQX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSU72 phosphatase family.
messages: Nucleus
messages: Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination.

89673:TAF1B
gene id: 89673:TAF1B
uniprot id: A0A6J2LZG7
uniprot id: A0A7E6DWD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRN7/TAF1B family.
messages: Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment as a component of the SL1/TIF-IB complex and, possibly, directly through its interaction with RRN3.
messages: nucleolus

89673:ATP13A1
gene id: 89673:ATP13A1
uniprot id: A0A7E6EHG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

89673:ECHDC1
gene id: 89673:ECHDC1
uniprot id: A0A6J2LHY3
uniprot id: A0A6J2LLB7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

89673:UBE2N
gene id: 89673:UBE2N
uniprot id: A0A6J2LM97
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

89673:SMDT1
gene id: 89673:SMDT1
uniprot id: A0A6J2N9P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMDT1/EMRE family.
messages: Component of the uniplex complex. Interacts (via the transmembrane region) with MCU (via the first transmembrane region); the interaction is direct.
messages: Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

89673:UBR2
gene id: 89673:UBR2
uniprot id: A0A6J2LBR1
uniprot id: A0A6J2LEG7
uniprot id: A0A7E6DP22
uniprot id: A0A7E6DPK8
uniprot id: A0A7E6DQ46
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

89673:ADAMTS5
gene id: 89673:ADAMTS5
uniprot id: A0A6J2L5Q7
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

89673:EPOR
gene id: 89673:EPOR
uniprot id: A0A6J2MA55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Forms homodimers on EPO stimulation.
messages: Membrane
messages: Receptor for erythropoietin.

89673:ZNF215
gene id: 89673:ZNF215
uniprot id: A0A6J2M0H6
uniprot id: A0A7E6E1B9
names: Subcellular Location Annotation
messages: Nucleus

89673:FZD4
gene id: 89673:FZD4
uniprot id: A0A6J2LYG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Membrane

89673:LOC114513353
gene id: 89673:LOC114513353
uniprot id: A0A6J2N7C5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:ATP5F1E
gene id: 89673:ATP5F1E
uniprot id: A0A6J2MM84
names: Function
names: Similarity
messages: Belongs to the eukaryotic ATPase epsilon family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

89673:CDH24
gene id: 89673:CDH24
uniprot id: A0A6J2L755
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

89673:DCLRE1C
gene id: 89673:DCLRE1C
uniprot id: A0A6J2LCA1
uniprot id: A0A7E6DLC5
uniprot id: A0A7E6DLD6
uniprot id: A0A7E6DLQ8
uniprot id: A0A7E6DM49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

89673:APC
gene id: 89673:APC
uniprot id: A0A6J2L900
uniprot id: A0A6J2L9F6
uniprot id: A0A6J2LAQ5
uniprot id: A0A6J2LAR1
uniprot id: A0A6J2LDH7
uniprot id: A0A6J2LDI2
uniprot id: A0A7E6DB23
uniprot id: A0A7E6DB68
uniprot id: A0A7E6DC97
uniprot id: A0A7E6DDE5
names: Similarity
messages: Belongs to the adenomatous polyposis coli (APC) family.

89673:SLC8B1
gene id: 89673:SLC8B1
uniprot id: A0A7E6CS02
names: Subcellular Location Annotation
messages: Membrane

89673:GNA12
gene id: 89673:GNA12
uniprot id: A0A6J2MU52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

89673:TMEM265
gene id: 89673:TMEM265
uniprot id: A0A6J2N205
names: Similarity
messages: Belongs to the CD225/Dispanin family.

89673:TMC1
gene id: 89673:TMC1
uniprot id: A0A6J2L0R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

89673:AGXT2
gene id: 89673:AGXT2
uniprot id: A0A6J2MT20
uniprot id: A0A7E6D9Z8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

89673:LOC114496071
gene id: 89673:LOC114496071
uniprot id: A0A6J2LMV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

89673:SERPINA5
gene id: 89673:SERPINA5
uniprot id: A0A6J2LBI7
names: Similarity
messages: Belongs to the serpin family.

89673:FAM13A
gene id: 89673:FAM13A
uniprot id: A0A6J2L493
uniprot id: A0A6J2L6A9
uniprot id: A0A7E6DTF6
uniprot id: A0A7E6DTJ3
uniprot id: A0A7E6DTV8
uniprot id: A0A7E6DU27
uniprot id: A0A7E6DU67
uniprot id: A0A7E6DU71
uniprot id: A0A7E6DUJ3
uniprot id: A0A7E6DUN0
uniprot id: A0A7E6DUN5
names: Similarity
messages: Belongs to the FAM13 family.

89673:C6H11orf87
gene id: 89673:C6H11orf87
uniprot id: A0A6J2M5M1
names: Subcellular Location Annotation
messages: Membrane

89673:PROK1
gene id: 89673:PROK1
uniprot id: A0A6J2KST5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AVIT (prokineticin) family.
messages: Secreted

89673:ARAP2
gene id: 89673:ARAP2
uniprot id: A0A6J2L8R0
uniprot id: A0A7E6D979
uniprot id: A0A7E6DBB6
names: Subcellular Location Annotation
messages: Cytoplasm

89673:JUND
gene id: 89673:JUND
uniprot id: A0A6J2M5W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

89673:LOC114495081
gene id: 89673:LOC114495081
uniprot id: A0A7E6DN28
names: Subcellular Location Annotation
messages: Membrane
messages: Sarcoplasmic reticulum membrane

89673:NQO1
gene id: 89673:NQO1
uniprot id: A0A6J2KT16
names: Similarity
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family.

89673:LOC114498565
gene id: 89673:LOC114498565
uniprot id: A0A6J2LSN5
uniprot id: A0A7E6DYQ1
uniprot id: A0A7E6DZ82
names: Similarity
messages: Belongs to the glycosyl hydrolase 37 family.

89673:LOC114497384
gene id: 89673:LOC114497384
uniprot id: A0A6J2LM97
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

89673:LOC114509361
gene id: 89673:LOC114509361
uniprot id: A0A7E6CRB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-5A synthase family.
messages: Cytoplasm

89673:HADH
gene id: 89673:HADH
uniprot id: A0A6J2L410
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

89673:SEPTIN7
gene id: 89673:SEPTIN7
uniprot id: A0A6J2MNP5
uniprot id: A0A6J2MNT2
uniprot id: A0A6J2MT29
uniprot id: A0A7E6CHL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Filament-forming cytoskeletal GTPase.
messages: Midbody
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.
messages: cilium axoneme
messages: flagellum
messages: kinetochore
messages: spindle

89673:NEUROD4
gene id: 89673:NEUROD4
uniprot id: A0A6J2NEQ8
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114497619
gene id: 89673:LOC114497619
uniprot id: A0A7E6DTS3
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

89673:TMEM150C
gene id: 89673:TMEM150C
uniprot id: A0A7E6DWR8
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114505032
gene id: 89673:LOC114505032
uniprot id: A0A7E6D1G9
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

89673:ASF1B
gene id: 89673:ASF1B
uniprot id: A0A6J2MGG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

89673:NPC1L1
gene id: 89673:NPC1L1
uniprot id: A0A6J2L2T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

89673:GPR21
gene id: 89673:GPR21
uniprot id: A0A6J2LAM8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:LOC114489398
gene id: 89673:LOC114489398
uniprot id: A0A6J2KWV1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:RECQL4
gene id: 89673:RECQL4
uniprot id: A0A7E6E8T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecQ subfamily.
messages: Nucleus

89673:ATP6V0A4
gene id: 89673:ATP6V0A4
uniprot id: A0A6J2MVH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

89673:CCKAR
gene id: 89673:CCKAR
uniprot id: A0A6J2L9C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

89673:EZH2
gene id: 89673:EZH2
uniprot id: A0A7E6CL23
names: Subcellular Location Annotation
messages: Nucleus

89673:SOX2
gene id: 89673:SOX2
uniprot id: A0A6J2NIG5
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114490214
gene id: 89673:LOC114490214
uniprot id: A0A6J2KZ79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114489252
gene id: 89673:LOC114489252
uniprot id: A0A6J2KYE7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:GMFB
gene id: 89673:GMFB
uniprot id: A0A6J2L7M3
names: Similarity
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.

89673:PLPP3
gene id: 89673:PLPP3
uniprot id: A0A6J2LI73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

89673:CRLS1
gene id: 89673:CRLS1
uniprot id: A0A6J2MJB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

89673:VPS36
gene id: 89673:VPS36
uniprot id: A0A6J2MX36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS36 family.
messages: Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).
messages: Cytoplasm
messages: Endosome

89673:CXCR2
gene id: 89673:CXCR2
uniprot id: A0A6J2LDB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:LOC114498754
gene id: 89673:LOC114498754
uniprot id: A0A7E6DWU6
names: Subcellular Location Annotation
messages: Nucleus

89673:NCAPG
gene id: 89673:NCAPG
uniprot id: A0A6J2L3U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND3 (condensin subunit 3) family.
messages: Chromosome

89673:FRG1
gene id: 89673:FRG1
uniprot id: A0A6J2MQI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRG1 family.
messages: Cajal body
messages: nucleolus

89673:DARS2
gene id: 89673:DARS2
uniprot id: A0A6J2N3Y2
uniprot id: A0A7E6CXU0
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.

89673:LOC114510654
gene id: 89673:LOC114510654
uniprot id: A0A6J2N448
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:AXL
gene id: 89673:AXL
uniprot id: A0A6J2MYL5
uniprot id: A0A6J2N4X6
uniprot id: A0A7E6CM14
uniprot id: A0A7E6CPA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Membrane

89673:CD3G
gene id: 89673:CD3G
uniprot id: A0A7E6E051
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Membrane
messages: The TCR-CD3 complex is composed of a CD3D/CD3E and a CD3G/CD3E heterodimers that preferentially associate with TCRalpha and TCRbeta, respectively, to form TCRalpha/CD3E/CD3G and TCRbeta/CD3G/CD3E trimers. In turn, the hexamer interacts with CD3Z homodimer to form the TCR-CD3 complex. Alternatively, TCRalpha and TCRbeta can be replaced by TCRgamma and TCRdelta.

89673:ITGAM
gene id: 89673:ITGAM
uniprot id: A0A6J2LRU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

89673:TUBD1
gene id: 89673:TUBD1
uniprot id: A0A6J2M7U9
uniprot id: A0A6J2MBQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: Nucleus
messages: centriole
messages: cilium

89673:AP3M1
gene id: 89673:AP3M1
uniprot id: A0A6J2LN86
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

89673:LOC114500145
gene id: 89673:LOC114500145
uniprot id: A0A6J2M2W4
uniprot id: A0A7E6DYF0
names: Similarity
messages: Belongs to the AHA1 family.

89673:NOTCH2
gene id: 89673:NOTCH2
uniprot id: A0A6J2KTJ7
uniprot id: A0A6J2KYY0
uniprot id: A0A7E6CWZ5
uniprot id: A0A7E6CXH6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

89673:GALE
gene id: 89673:GALE
uniprot id: A0A6J2LPE2
uniprot id: A0A7E6DR32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids.
messages: Homodimer.

89673:TMEM138
gene id: 89673:TMEM138
uniprot id: A0A6J2M0S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM138 family.
messages: Membrane
messages: Required for ciliogenesis.
messages: Vacuole membrane
messages: cilium

89673:GLCE
gene id: 89673:GLCE
uniprot id: A0A6J2L1S9
names: Similarity
messages: Belongs to the D-glucuronyl C5-epimerase family.

89673:LOC114501854
gene id: 89673:LOC114501854
uniprot id: A0A6J2M814
uniprot id: A0A7E6E3Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Secreted

89673:AGPAT3
gene id: 89673:AGPAT3
uniprot id: A0A6J2L0G5
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

89673:AAR2
gene id: 89673:AAR2
uniprot id: A0A6J2MJK7
names: Function
names: Similarity
messages: Belongs to the AAR2 family.
messages: Component of the U5 snRNP complex that is required for spliceosome assembly and for pre-mRNA splicing.

89673:CEBPG
gene id: 89673:CEBPG
uniprot id: A0A6J2N0K2
uniprot id: A0A7E6CN61
names: Similarity
messages: Belongs to the bZIP family. C/EBP subfamily.

89673:LOC114507234
gene id: 89673:LOC114507234
uniprot id: A0A6J2MSL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

89673:FZD1
gene id: 89673:FZD1
uniprot id: A0A6J2MPL2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:METAP2
gene id: 89673:METAP2
uniprot id: A0A6J2N6N1
uniprot id: A0A6J2NBZ1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Binds EIF2S1 at low magnesium concentrations. Interacts strongly with the eIF-2 gamma-subunit EIF2S3.
messages: Contains approximately 12 O-linked N-acetylglucosamine (GlcNAc) residues. O-glycosylation is required for EIF2S1 binding.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Cytoplasm
messages: Protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2/PKR and EIF2AK1/HCR. Plays a critical role in the regulation of protein synthesis.

89673:PARP9
gene id: 89673:PARP9
uniprot id: A0A7E6D465
uniprot id: A0A7E6D4W5
names: Similarity
messages: Belongs to the ARTD/PARP family.

89673:FAM229B
gene id: 89673:FAM229B
uniprot id: A0A6J2LEQ3
names: Similarity
messages: Belongs to the FAM229 family.

89673:UBE2R2
gene id: 89673:UBE2R2
uniprot id: A0A6J2LNB3
uniprot id: A0A7E6DFC0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

89673:OXA1L
gene id: 89673:OXA1L
uniprot id: A0A6J2LB02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

89673:IDO2
gene id: 89673:IDO2
uniprot id: A0A6J2MQW4
uniprot id: A0A7E6CKN4
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

89673:LOC114500268
gene id: 89673:LOC114500268
uniprot id: A0A6J2LZE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SERPINB7
gene id: 89673:SERPINB7
uniprot id: A0A6J2MMS7
names: Similarity
messages: Belongs to the serpin family.

89673:ACLY
gene id: 89673:ACLY
uniprot id: A0A6J2MBF9
uniprot id: A0A6J2MDM0
uniprot id: A0A6J2MGM2
uniprot id: A0A6J2MHG1
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
messages: In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.

89673:LOC114508000
gene id: 89673:LOC114508000
uniprot id: A0A6J2MNN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:MLF2
gene id: 89673:MLF2
uniprot id: A0A6J2N673
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLF family.
messages: Cytoplasm

89673:TNFSF8
gene id: 89673:TNFSF8
uniprot id: A0A6J2M6T5
names: Similarity
messages: Belongs to the tumor necrosis factor family.

89673:LOC114510920
gene id: 89673:LOC114510920
uniprot id: A0A6J2N060
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LicD transferase family.
messages: Golgi apparatus membrane

89673:CLTRN
gene id: 89673:CLTRN
uniprot id: A0A6J2MF13
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:GDI2
gene id: 89673:GDI2
uniprot id: A0A6J2L130
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

89673:LOC114504923
gene id: 89673:LOC114504923
uniprot id: A0A7E6D1C6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIIc family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits, encoded in the mitochondrial DNA, and 11 supernumerary subunits, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

89673:PI4K2B
gene id: 89673:PI4K2B
uniprot id: A0A7E6D7W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
messages: Membrane

89673:HOMER1
gene id: 89673:HOMER1
uniprot id: A0A6J2LFL0
uniprot id: A0A7E6DBP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

89673:HSD17B12
gene id: 89673:HSD17B12
uniprot id: A0A6J2LXG9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

89673:LOC114514446
gene id: 89673:LOC114514446
uniprot id: A0A6J2NH25
names: Similarity
messages: Belongs to the cytochrome P450 family.

89673:TGM7
gene id: 89673:TGM7
uniprot id: A0A7E6E9A4
uniprot id: A0A7E6EAB3
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

89673:SRD5A1
gene id: 89673:SRD5A1
uniprot id: A0A6J2MG78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane
messages: Microsome membrane

89673:ELK4
gene id: 89673:ELK4
uniprot id: A0A6J2N9Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

89673:NAPB
gene id: 89673:NAPB
uniprot id: A0A6J2MHB4
uniprot id: A0A6J2MJ33
uniprot id: A0A6J2MJE9
uniprot id: A0A6J2MN73
uniprot id: A0A7E6CE97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

89673:FREM2
gene id: 89673:FREM2
uniprot id: A0A6J2MS87
names: Similarity
messages: Belongs to the FRAS1 family.

89673:AK8
gene id: 89673:AK8
uniprot id: A0A6J2MV98
uniprot id: A0A7E6DGU3
uniprot id: A0A7E6DGZ8
uniprot id: A0A7E6DH19
uniprot id: A0A7E6DH69
names: Similarity
messages: Belongs to the adenylate kinase family.

89673:LOC114512923
gene id: 89673:LOC114512923
uniprot id: A0A7E6CZG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRK1 family.
messages: cytoskeleton

89673:PRIMPOL
gene id: 89673:PRIMPOL
uniprot id: A0A6J2MT01
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

89673:SMYD2
gene id: 89673:SMYD2
uniprot id: A0A6J2N9D9
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically trimethylates histone H3 'Lys-4' (H3K4me3) in vivo. The activity requires interaction with HSP90alpha. Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'.
messages: cytosol

89673:LOC114499053
gene id: 89673:LOC114499053
uniprot id: A0A6J2LTZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ROR1
gene id: 89673:ROR1
uniprot id: A0A6J2LJK6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:TNFSF12
gene id: 89673:TNFSF12
uniprot id: A0A6J2NDX1
names: Similarity
messages: Belongs to the tumor necrosis factor family.

89673:CCDC103
gene id: 89673:CCDC103
uniprot id: A0A7E6EE96
uniprot id: A0A7E6EET7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CCDC103/PR46b family.
messages: Cytoplasm
messages: Dynein-attachment factor required for cilia motility.
messages: Homodimer.
messages: flagellum

89673:TMEM45B
gene id: 89673:TMEM45B
uniprot id: A0A6J2MWW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

89673:SNX21
gene id: 89673:SNX21
uniprot id: A0A6J2MPV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Membrane

89673:SERPINB12
gene id: 89673:SERPINB12
uniprot id: A0A7E6CGI0
names: Similarity
messages: Belongs to the serpin family.

89673:EXOC2
gene id: 89673:EXOC2
uniprot id: A0A6J2LI13
uniprot id: A0A7E6DU36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SEC5 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: Component of the exocyst complex.

89673:GTF2F2
gene id: 89673:GTF2F2
uniprot id: A0A6J2MQE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB.

89673:LOC114509913
gene id: 89673:LOC114509913
uniprot id: A0A6J2MXJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SPP1
gene id: 89673:SPP1
uniprot id: A0A6J2L8D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the osteopontin family.
messages: Secreted

89673:ANKS1B
gene id: 89673:ANKS1B
uniprot id: A0A6J2N5C2
uniprot id: A0A6J2N755
uniprot id: A0A6J2N760
uniprot id: A0A6J2N7E8
uniprot id: A0A6J2N7F6
uniprot id: A0A6J2NCK7
uniprot id: A0A6J2NCL7
uniprot id: A0A7E6D7T9
uniprot id: A0A7E6D7U4
uniprot id: A0A7E6D802
uniprot id: A0A7E6D8K1
uniprot id: A0A7E6D8K6
uniprot id: A0A7E6DAQ8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

89673:LOC114504280
gene id: 89673:LOC114504280
uniprot id: A0A6J2MCP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:AP1G2
gene id: 89673:AP1G2
uniprot id: A0A6J2LAD9
uniprot id: A0A7E6E3B6
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

89673:PADI3
gene id: 89673:PADI3
uniprot id: A0A7E6DQQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Catalyzes the deimination of arginine residues of proteins.
messages: Cytoplasm

89673:EIF1B
gene id: 89673:EIF1B
uniprot id: A0A6J2M3J7
names: Similarity
messages: Belongs to the SUI1 family.

89673:LAMP5
gene id: 89673:LAMP5
uniprot id: A0A7E6CGR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane
messages: Membrane

89673:LOC114499169
gene id: 89673:LOC114499169
uniprot id: A0A7E6E493
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114490183
gene id: 89673:LOC114490183
uniprot id: A0A6J2KXG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:RBX1
gene id: 89673:RBX1
uniprot id: A0A6J2NE05
names: Similarity
messages: Belongs to the RING-box family.

89673:ITPKB
gene id: 89673:ITPKB
uniprot id: A0A6J2N3N2
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

89673:PSD
gene id: 89673:PSD
uniprot id: A0A6J2LK01
names: Subcellular Location Annotation
messages: Membrane
messages: ruffle membrane

89673:LAMTOR3
gene id: 89673:LAMTOR3
uniprot id: A0A6J2L9P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMTOR3 family.
messages: Endosome membrane
messages: Late endosome membrane

89673:NPLOC4
gene id: 89673:NPLOC4
uniprot id: A0A7E6CE03
names: Similarity
messages: Belongs to the NPL4 family.

89673:GCFC2
gene id: 89673:GCFC2
uniprot id: A0A7E6DY02
uniprot id: A0A7E6DYZ9
names: Similarity
messages: Belongs to the GCF family.

89673:MTHFS
gene id: 89673:MTHFS
uniprot id: A0A6J2KSF5
uniprot id: A0A7E6CQ33
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

89673:PAXBP1
gene id: 89673:PAXBP1
uniprot id: A0A6J2L299
names: Similarity
messages: Belongs to the GCF family.

89673:LIFR
gene id: 89673:LIFR
uniprot id: A0A6J2MNK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

89673:SF3A1
gene id: 89673:SF3A1
uniprot id: A0A6J2MSJ7
names: Subcellular Location Annotation
messages: Nucleus

89673:KRT5
gene id: 89673:KRT5
uniprot id: A0A6J2NDY2
names: Similarity
messages: Belongs to the intermediate filament family.

89673:OGFOD1
gene id: 89673:OGFOD1
uniprot id: A0A6J2KQW7
uniprot id: A0A7E6CLI5
names: Similarity
messages: Belongs to the TPA1 family.

89673:IL17RC
gene id: 89673:IL17RC
uniprot id: A0A7E6E556
uniprot id: A0A7E6E561
uniprot id: A0A7E6E5R8
uniprot id: A0A7E6E5W1
uniprot id: A0A7E6E5W8
uniprot id: A0A7E6E6P6
uniprot id: A0A7E6E6Q0
names: Subcellular Location Annotation
messages: Membrane

89673:PACSIN2
gene id: 89673:PACSIN2
uniprot id: A0A6J2N914
uniprot id: A0A6J2NAQ5
uniprot id: A0A6J2NFS4
uniprot id: A0A6J2NGI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PACSIN family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Early endosome
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: caveola
messages: cytoskeleton
messages: ruffle membrane

89673:GABRR2
gene id: 89673:GABRR2
uniprot id: A0A6J2LFG0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Interacts with SQSTM1.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

89673:MMP11
gene id: 89673:MMP11
uniprot id: A0A7E6CT66
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

89673:LOC114507885
gene id: 89673:LOC114507885
uniprot id: A0A6J2MQF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SYCE1
gene id: 89673:SYCE1
uniprot id: A0A7E6DWH4
names: Similarity
messages: Belongs to the SYCE family.

89673:LOC114488208
gene id: 89673:LOC114488208
uniprot id: A0A6J2KWN3
uniprot id: A0A6J2L5F6
uniprot id: A0A7E6CQI7
names: Similarity
messages: Belongs to the UPF0547 family.

89673:HSF2
gene id: 89673:HSF2
uniprot id: A0A6J2LAG9
uniprot id: A0A6J2LF40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

89673:DCLK2
gene id: 89673:DCLK2
uniprot id: A0A6J2MBK6
uniprot id: A0A6J2MEH9
uniprot id: A0A7E6E834
uniprot id: A0A7E6E8T1
uniprot id: A0A7E6E903
uniprot id: A0A7E6E9M4
uniprot id: A0A7E6E9Z8
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

89673:ADAM11
gene id: 89673:ADAM11
uniprot id: A0A6J2M7V9
uniprot id: A0A6J2MB57
uniprot id: A0A7E6EG05
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:ADGRG1
gene id: 89673:ADGRG1
uniprot id: A0A6J2KUM9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: Secreted

89673:NPR2
gene id: 89673:NPR2
uniprot id: A0A6J2LCC8
uniprot id: A0A7E6DFJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

89673:MCTP2
gene id: 89673:MCTP2
uniprot id: A0A6J2KRY7
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114504764
gene id: 89673:LOC114504764
uniprot id: A0A6J2MGI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114513372
gene id: 89673:LOC114513372
uniprot id: A0A6J2NEU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SNCA
gene id: 89673:SNCA
uniprot id: A0A6J2L5S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synuclein family.
messages: Membrane
messages: Nucleus
messages: Secreted
messages: Synapse
messages: axon

89673:PCSK1
gene id: 89673:PCSK1
uniprot id: A0A6J2M6A6
uniprot id: A0A7E6DAV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin, insulin and AGRP.
messages: Vesicle
messages: secretory vesicle

89673:FNTA
gene id: 89673:FNTA
uniprot id: A0A6J2MX23
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

89673:PMEPA1
gene id: 89673:PMEPA1
uniprot id: A0A6J2ML81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMEPA1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

89673:MTG2
gene id: 89673:MTG2
uniprot id: A0A6J2MM27
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

89673:ASF1A
gene id: 89673:ASF1A
uniprot id: A0A6J2LET1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

89673:LOC118499275
gene id: 89673:LOC118499275
uniprot id: A0A7E6D9A0
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

89673:TDO2
gene id: 89673:TDO2
uniprot id: A0A6J2M9S2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer. Dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:FGF2
gene id: 89673:FGF2
uniprot id: A0A6J2M5U1
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

89673:EXOC4
gene id: 89673:EXOC4
uniprot id: A0A6J2MTL3
uniprot id: A0A7E6CIX5
uniprot id: A0A7E6CJ02
names: Function
names: Similarity
messages: Belongs to the SEC8 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

89673:VWC2
gene id: 89673:VWC2
uniprot id: A0A7E6CHB3
names: Subcellular Location Annotation
messages: Synapse

89673:COPS5
gene id: 89673:COPS5
uniprot id: A0A6J2NAG0
uniprot id: A0A6J2NC36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M67A family. CSN5 subfamily.
messages: synaptic vesicle

89673:ARL2
gene id: 89673:ARL2
uniprot id: A0A6J2LUS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

89673:PRPF3
gene id: 89673:PRPF3
uniprot id: A0A6J2KYJ3
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).

89673:CNTNAP1
gene id: 89673:CNTNAP1
uniprot id: A0A6J2MCM5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: paranodal septate junction

89673:MAN1A1
gene id: 89673:MAN1A1
uniprot id: A0A6J2LCC2
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

89673:LOC118497255
gene id: 89673:LOC118497255
uniprot id: A0A7E6CJB7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:S100A11
gene id: 89673:S100A11
uniprot id: A0A6J2KTF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the S-100 family.
messages: Facilitates the differentiation and the cornification of keratinocytes.
messages: Homodimer; disulfide-linked.

89673:FAXC
gene id: 89673:FAXC
uniprot id: A0A7E6DN82
names: Similarity
messages: Belongs to the FAX family.

89673:KIF18B
gene id: 89673:KIF18B
uniprot id: A0A6J2M9T5
uniprot id: A0A7E6EF25
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

89673:LOC114492584
gene id: 89673:LOC114492584
uniprot id: A0A6J2LAX6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:CD109
gene id: 89673:CD109
uniprot id: A0A6J2LLJ7
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.

89673:NUPR2
gene id: 89673:NUPR2
uniprot id: A0A6J2MLK5
names: Similarity
messages: Belongs to the NUPR family.

89673:IFI44L
gene id: 89673:IFI44L
uniprot id: A0A6J2LHZ1
names: Similarity
messages: Belongs to the IFI44 family.

89673:TM9SF2
gene id: 89673:TM9SF2
uniprot id: A0A6J2MRH1
uniprot id: A0A7E6CKA1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:SYNGR1
gene id: 89673:SYNGR1
uniprot id: A0A6J2N9B6
uniprot id: A0A6J2N9M6
uniprot id: A0A6J2NEA0
uniprot id: A0A6J2NEX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

89673:LOC114500308
gene id: 89673:LOC114500308
uniprot id: A0A6J2M3G2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CASC3
gene id: 89673:CASC3
uniprot id: A0A6J2M5Y1
uniprot id: A0A7E6EFE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CASC3 family.
messages: Nucleus speckle
messages: dendrite
messages: perinuclear region

89673:CNPY1
gene id: 89673:CNPY1
uniprot id: A0A7E6CJ52
names: Similarity
messages: Belongs to the canopy family.

89673:LOC114496179
gene id: 89673:LOC114496179
uniprot id: A0A7E6DPR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

89673:BMPR1B
gene id: 89673:BMPR1B
uniprot id: A0A6J2L8Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

89673:TMOD4
gene id: 89673:TMOD4
uniprot id: A0A6J2KYW7
uniprot id: A0A7E6CXX7
names: Subcellular Location Annotation
messages: cytoskeleton

89673:CCK
gene id: 89673:CCK
uniprot id: A0A6J2M9H8
uniprot id: A0A7E6E470
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gastrin/cholecystokinin family.
messages: Secreted

89673:LOC114490157
gene id: 89673:LOC114490157
uniprot id: A0A6J2L2N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:IGF2R
gene id: 89673:IGF2R
uniprot id: A0A6J2LEQ9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114504892
gene id: 89673:LOC114504892
uniprot id: A0A7E6CZV6
names: Similarity
messages: Belongs to the E2F/DP family.

89673:BID
gene id: 89673:BID
uniprot id: A0A6J2MSN3
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Forms heterodimers either with the pro-apoptotic protein BAX or the anti-apoptotic protein BCL2.
messages: Induces caspases and apoptosis. Counters the protective effect of BCL2.
messages: Intact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family.
messages: Membrane
messages: Mitochondrion outer membrane

89673:BAZ1A
gene id: 89673:BAZ1A
uniprot id: A0A6J2L990
names: Subcellular Location Annotation
messages: Nucleus

89673:PKD1
gene id: 89673:PKD1
uniprot id: A0A7E6DBZ8
uniprot id: A0A7E6DC88
uniprot id: A0A7E6DD40
uniprot id: A0A7E6DDM0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:LOC114508650
gene id: 89673:LOC114508650
uniprot id: A0A6J2MSF0
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

89673:CATSPERE
gene id: 89673:CATSPERE
uniprot id: A0A7E6CYU3
names: Similarity
messages: Belongs to the CATSPERD family.

89673:LOC114490366
gene id: 89673:LOC114490366
uniprot id: A0A7E6E755
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SMC1B
gene id: 89673:SMC1B
uniprot id: A0A7E6D8S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Chromosome
messages: Nucleus

89673:LYRM9
gene id: 89673:LYRM9
uniprot id: A0A6J2MCN1
names: Similarity
messages: Belongs to the complex I LYR family. LYRM9 subfamily.

89673:TMEM39A
gene id: 89673:TMEM39A
uniprot id: A0A6J2L0W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM39 family.
messages: Membrane

89673:LOC114507542
gene id: 89673:LOC114507542
uniprot id: A0A7E6CI67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the F-actin-capping protein beta subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.
messages: cytoskeleton

89673:LOC114503698
gene id: 89673:LOC114503698
uniprot id: A0A6J2MGE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:PPARG
gene id: 89673:PPARG
uniprot id: A0A6J2M4W9
uniprot id: A0A6J2M8H4
uniprot id: A0A7E6E6Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Cytoplasm
messages: Heterodimer with other nuclear receptors.
messages: Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. May play a role in the regulation of circadian rhythm.
messages: Nucleus

89673:HCFC2
gene id: 89673:HCFC2
uniprot id: A0A6J2N5K2
uniprot id: A0A7E6D8R3
names: Subcellular Location Annotation
messages: Nucleus

89673:HIGD1B
gene id: 89673:HIGD1B
uniprot id: A0A6J2MF34
uniprot id: A0A7E6EFU8
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

89673:ANO3
gene id: 89673:ANO3
uniprot id: A0A6J2LYJ6
uniprot id: A0A6J2M201
uniprot id: A0A6J2M206
uniprot id: A0A7E6E0M5
uniprot id: A0A7E6E0Z6
uniprot id: A0A7E6E1V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Membrane

89673:DIPK2B
gene id: 89673:DIPK2B
uniprot id: A0A6J2MGX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Secreted

89673:TCP11L2
gene id: 89673:TCP11L2
uniprot id: A0A6J2NGJ1
names: Similarity
messages: Belongs to the TCP11 family.

89673:MTMR6
gene id: 89673:MTMR6
uniprot id: A0A6J2KXY0
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

89673:LOC114490403
gene id: 89673:LOC114490403
uniprot id: A0A6J2KY56
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:TAC3
gene id: 89673:TAC3
uniprot id: A0A6J2N8M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted

89673:OPN3
gene id: 89673:OPN3
uniprot id: A0A6J2N9W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

89673:LOC114494199
gene id: 89673:LOC114494199
uniprot id: A0A7E6DN41
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

89673:LOC114514394
gene id: 89673:LOC114514394
uniprot id: A0A7E6E775
names: Subcellular Location Annotation
messages: Membrane

89673:CHRD
gene id: 89673:CHRD
uniprot id: A0A6J2L0U1
uniprot id: A0A7E6D322
uniprot id: A0A7E6D3T3
uniprot id: A0A7E6D5W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chordin family.
messages: Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes.
messages: Secreted

89673:SLC27A2
gene id: 89673:SLC27A2
uniprot id: A0A6J2L9A8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

89673:OTULIN
gene id: 89673:OTULIN
uniprot id: A0A6J2LR91
uniprot id: A0A7E6DA31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C65 family. Otulin subfamily.
messages: Cytoplasm

89673:LOC114514121
gene id: 89673:LOC114514121
uniprot id: A0A7E6DFZ3
uniprot id: A0A7E6DFZ7
uniprot id: A0A7E6DG52
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

89673:IER5
gene id: 89673:IER5
uniprot id: A0A6J2N3W4
names: Similarity
messages: Belongs to the IER family.

89673:NAT10
gene id: 89673:NAT10
uniprot id: A0A6J2LYR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.
messages: Interacts with THUMPD1.
messages: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA-binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
messages: nucleolus

89673:ME1
gene id: 89673:ME1
uniprot id: A0A6J2LH36
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

89673:SORCS3
gene id: 89673:SORCS3
uniprot id: A0A6J2LQ40
uniprot id: A0A7E6DVG2
names: Similarity
messages: Belongs to the VPS10-related sortilin family. SORCS subfamily.

89673:COPB1
gene id: 89673:COPB1
uniprot id: A0A6J2LZL2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Endoplasmic reticulum-Golgi intermediate compartment
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

89673:ADPRH
gene id: 89673:ADPRH
uniprot id: A0A6J2L401
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

89673:LOC114504575
gene id: 89673:LOC114504575
uniprot id: A0A6J2MFG6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

89673:RPL27A
gene id: 89673:RPL27A
uniprot id: A0A6J2LZ83
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

89673:TFAP2A
gene id: 89673:TFAP2A
uniprot id: A0A7E6DTB6
uniprot id: A0A7E6DTG0
uniprot id: A0A7E6DTH0
uniprot id: A0A7E6DTX4
uniprot id: A0A7E6DTX9
uniprot id: A0A7E6DU39
uniprot id: A0A7E6DUJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AP-2 family.
messages: Nucleus

89673:DOP1A
gene id: 89673:DOP1A
uniprot id: A0A6J2LFB3
uniprot id: A0A6J2LGB7
uniprot id: A0A6J2LGC5
uniprot id: A0A6J2LK24
uniprot id: A0A7E6DMC8
uniprot id: A0A7E6DMW2
uniprot id: A0A7E6DN60
names: Similarity
messages: Belongs to the dopey family.

89673:LOC114499029
gene id: 89673:LOC114499029
uniprot id: A0A7E6DX60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:DDX56
gene id: 89673:DDX56
uniprot id: A0A6J2KXM6
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

89673:GPR65
gene id: 89673:GPR65
uniprot id: A0A6J2LCY6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:MMP19
gene id: 89673:MMP19
uniprot id: A0A7E6D685
uniprot id: A0A7E6D912
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

89673:LOC114500662
gene id: 89673:LOC114500662
uniprot id: A0A6J2M4P6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SOX1
gene id: 89673:SOX1
uniprot id: A0A6J2MXF2
names: Subcellular Location Annotation
messages: Nucleus

89673:EIF4ENIF1
gene id: 89673:EIF4ENIF1
uniprot id: A0A6J2MTS4
uniprot id: A0A6J2MTS6
uniprot id: A0A6J2MYS2
uniprot id: A0A7E6CRH3
names: Subcellular Location Annotation
messages: Cytoplasm

89673:EFHC2
gene id: 89673:EFHC2
uniprot id: A0A6J2MI42
uniprot id: A0A7E6CYS5
names: Subcellular Location Annotation
messages: cilium axoneme

89673:USP33
gene id: 89673:USP33
uniprot id: A0A7E6DT93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP20/USP33 subfamily.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: centrosome
messages: perinuclear region

89673:UCHL5
gene id: 89673:UCHL5
uniprot id: A0A6J2N5M1
uniprot id: A0A6J2NB28
uniprot id: A0A7E6CY62
names: Similarity
messages: Belongs to the peptidase C12 family.

89673:HABP2
gene id: 89673:HABP2
uniprot id: A0A6J2LUN3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:P2RY1
gene id: 89673:P2RY1
uniprot id: A0A6J2L023
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:LOC114502311
gene id: 89673:LOC114502311
uniprot id: A0A6J2M4D8
names: Subcellular Location Annotation
messages: Membrane

89673:KIF22
gene id: 89673:KIF22
uniprot id: A0A6J2MFH3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

89673:SLC39A2
gene id: 89673:SLC39A2
uniprot id: A0A6J2KZN0
uniprot id: A0A7E6E680
uniprot id: A0A7E6E709
names: Subcellular Location Annotation
messages: Membrane

89673:FOXC1
gene id: 89673:FOXC1
uniprot id: A0A6J2LQM3
uniprot id: A0A7E6DTG3
names: Subcellular Location Annotation
messages: Nucleus

89673:DYM
gene id: 89673:DYM
uniprot id: A0A6J2MMI9
uniprot id: A0A6J2MS03
names: Similarity
messages: Belongs to the dymeclin family.

89673:SLC16A9
gene id: 89673:SLC16A9
uniprot id: A0A6J2LNE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cell membrane
messages: Membrane

89673:DRAXIN
gene id: 89673:DRAXIN
uniprot id: A0A6J2LQ65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the draxin family.
messages: Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.
messages: Interacts with LRP6.
messages: Secreted

89673:ELAC1
gene id: 89673:ELAC1
uniprot id: A0A6J2MMY5
uniprot id: A0A7E6CGL6
names: Subunit
messages: Homodimer.

89673:LOC114499576
gene id: 89673:LOC114499576
uniprot id: A0A6J2LXD0
uniprot id: A0A7E6E0X6
names: Subcellular Location Annotation
messages: Membrane

89673:POLR3F
gene id: 89673:POLR3F
uniprot id: A0A6J2MKB0
uniprot id: A0A7E6CEG6
uniprot id: A0A7E6CF57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

89673:LOC114506659
gene id: 89673:LOC114506659
uniprot id: A0A6J2ML99
uniprot id: A0A7E6DG62
names: Similarity
names: Subunit
messages: Belongs to the CutA family.
messages: Homotrimer.

89673:AUH
gene id: 89673:AUH
uniprot id: A0A6J2N613
uniprot id: A0A6J2NBH3
uniprot id: A0A7E6DE64
uniprot id: A0A7E6DE88
uniprot id: A0A7E6DE97
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

89673:ISCA1
gene id: 89673:ISCA1
uniprot id: A0A6J2LTL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HesB/IscA family.
messages: Mitochondrion

89673:LOC114493866
gene id: 89673:LOC114493866
uniprot id: A0A6J2L9N2
names: Similarity
messages: Belongs to the GroES chaperonin family.

89673:TMEM63B
gene id: 89673:TMEM63B
uniprot id: A0A6J2LA42
uniprot id: A0A6J2LBD0
uniprot id: A0A7E6DLP3
uniprot id: A0A7E6DM65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

89673:PAPSS1
gene id: 89673:PAPSS1
uniprot id: A0A6J2L8G3
uniprot id: A0A7E6DRA8
names: Similarity
messages: In the C-terminal section; belongs to the sulfate adenylyltransferase family.
messages: In the N-terminal section; belongs to the APS kinase family.

89673:PLA2G4F
gene id: 89673:PLA2G4F
uniprot id: A0A6J2L598
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

89673:APPL2
gene id: 89673:APPL2
uniprot id: A0A6J2N8Q8
uniprot id: A0A6J2NAN6
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: Nucleus
messages: phagosome
messages: ruffle

89673:GALNT11
gene id: 89673:GALNT11
uniprot id: A0A6J2MU93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

89673:RPIA
gene id: 89673:RPIA
uniprot id: A0A6J2LUW9
uniprot id: A0A7E6DTK7
uniprot id: A0A7E6DUF3
names: Similarity
messages: Belongs to the ribose 5-phosphate isomerase family.

89673:TMPRSS13
gene id: 89673:TMPRSS13
uniprot id: A0A6J2LUE7
uniprot id: A0A7E6DYU7
uniprot id: A0A7E6DYX4
uniprot id: A0A7E6DZC1
uniprot id: A0A7E6DZT9
uniprot id: A0A7E6E069
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:GADD45G
gene id: 89673:GADD45G
uniprot id: A0A6J2NBI3
names: Similarity
messages: Belongs to the GADD45 family.

89673:LOC114495335
gene id: 89673:LOC114495335
uniprot id: A0A6J2LG67
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

89673:INSL3
gene id: 89673:INSL3
uniprot id: A0A6J2MHW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted
messages: Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor.

89673:LOC114492798
gene id: 89673:LOC114492798
uniprot id: A0A6J2L855
names: Similarity
messages: Belongs to the BolA/IbaG family.

89673:ARRDC4
gene id: 89673:ARRDC4
uniprot id: A0A6J2KSK4
names: Similarity
messages: Belongs to the arrestin family.

89673:LOC114498881
gene id: 89673:LOC114498881
uniprot id: A0A7E6E176
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SERPINB5
gene id: 89673:SERPINB5
uniprot id: A0A6J2MRL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the serpin family. Ov-serpin subfamily.
messages: extracellular space

89673:MCCC2
gene id: 89673:MCCC2
uniprot id: A0A6J2MRS7
names: Similarity
messages: Belongs to the AccD/PCCB family.

89673:LOC114497005
gene id: 89673:LOC114497005
uniprot id: A0A7E6DXG6
names: Subcellular Location Annotation
messages: Nucleus

89673:STRN3
gene id: 89673:STRN3
uniprot id: A0A6J2L9N8
uniprot id: A0A6J2LCM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

89673:SPIN1
gene id: 89673:SPIN1
uniprot id: A0A6J2N5Y2
names: Similarity
messages: Belongs to the SPIN/STSY family.

89673:CLK2
gene id: 89673:CLK2
uniprot id: A0A6J2KW46
uniprot id: A0A7E6CWR6
uniprot id: A0A7E6CX56
uniprot id: A0A7E6CXH4
uniprot id: A0A7E6CZA7
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:THADA
gene id: 89673:THADA
uniprot id: A0A6J2LT00
uniprot id: A0A7E6DXA0
uniprot id: A0A7E6DXN1
uniprot id: A0A7E6DY36
uniprot id: A0A7E6DYI5
names: Function
names: Similarity
messages: Belongs to the THADA family.
messages: Together with methyltransferase FTSJ1, methylates the 2'-O-ribose of nucleotides at position 32 of the anticodon loop of substrate tRNAs.

89673:FBXO32
gene id: 89673:FBXO32
uniprot id: A0A6J2NB41
uniprot id: A0A7E6E8L0
names: Subcellular Location Annotation
messages: Nucleus

89673:PPA2
gene id: 89673:PPA2
uniprot id: A0A6J2L8K2
uniprot id: A0A7E6DQY5
names: Similarity
messages: Belongs to the PPase family.

89673:YIPF6
gene id: 89673:YIPF6
uniprot id: A0A7E6D0G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Golgi apparatus membrane
messages: Membrane

89673:LDHB
gene id: 89673:LDHB
uniprot id: A0A6J2NA01
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

89673:LOC114514887
gene id: 89673:LOC114514887
uniprot id: A0A6J2NIE4
names: Similarity
messages: Belongs to the histone H3 family.

89673:GPR20
gene id: 89673:GPR20
uniprot id: A0A6J2ND87
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:MYMK
gene id: 89673:MYMK
uniprot id: A0A6J2N831
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Membrane

89673:HIBCH
gene id: 89673:HIBCH
uniprot id: A0A6J2LEU6
uniprot id: A0A7E6DJ07
uniprot id: A0A7E6DJ25
uniprot id: A0A7E6DJ85
uniprot id: A0A7E6DJ99
uniprot id: A0A7E6DJF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA.
messages: Mitochondrion

89673:LOC114507394
gene id: 89673:LOC114507394
uniprot id: A0A6J2MND3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:MIF
gene id: 89673:MIF
uniprot id: A0A6J2MV69
names: Similarity
messages: Belongs to the MIF family.

89673:NPSR1
gene id: 89673:NPSR1
uniprot id: A0A7E6CHQ3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:GPR1
gene id: 89673:GPR1
uniprot id: A0A7E6DIR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

89673:TTYH3
gene id: 89673:TTYH3
uniprot id: A0A6J2MYP5
uniprot id: A0A7E6CTP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

89673:DYRK1B
gene id: 89673:DYRK1B
uniprot id: A0A6J2MZ20
uniprot id: A0A6J2N0P8
uniprot id: A0A6J2N0R4
uniprot id: A0A6J2N658
uniprot id: A0A7E6CLG1
uniprot id: A0A7E6CLG8
uniprot id: A0A7E6CLH1
uniprot id: A0A7E6CLI2
uniprot id: A0A7E6CLJ0
uniprot id: A0A7E6CNN2
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

89673:C1H15orf65
gene id: 89673:C1H15orf65
uniprot id: A0A6J2L8R3
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with CFAP53, ODAD1 and ODAD3; the interactions link the outer dynein arms docking complex (ODA-DC) to the internal microtubule inner proteins (MIP) in cilium axoneme.
messages: cilium axoneme

89673:SLC10A1
gene id: 89673:SLC10A1
uniprot id: A0A6J2L977
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

89673:ZNF213
gene id: 89673:ZNF213
uniprot id: A0A6J2LF57
uniprot id: A0A6J2LHA5
uniprot id: A0A7E6DA76
names: Subcellular Location Annotation
messages: Nucleus

89673:PLXNB2
gene id: 89673:PLXNB2
uniprot id: A0A6J2N558
uniprot id: A0A7E6D8Q5
names: Caution
names: Similarity
messages: Belongs to the plexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:ESYT3
gene id: 89673:ESYT3
uniprot id: A0A6J2M2P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the extended synaptotagmin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:DTWD2
gene id: 89673:DTWD2
uniprot id: A0A6J2LL92
names: Similarity
messages: Belongs to the TDD superfamily. DTWD2 family.

89673:RGMB
gene id: 89673:RGMB
uniprot id: A0A6J2LU25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

89673:LOC114488211
gene id: 89673:LOC114488211
uniprot id: A0A6J2KUF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARL2BP family.
messages: Cytoplasm
messages: Mitochondrion intermembrane space
messages: Nucleus
messages: Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2.
messages: centrosome
messages: cilium basal body

89673:RARRES2
gene id: 89673:RARRES2
uniprot id: A0A6J2MUF4
names: Subcellular Location Annotation
messages: Secreted

89673:MAGI1
gene id: 89673:MAGI1
uniprot id: A0A6J2M5W7
uniprot id: A0A7E6E758
uniprot id: A0A7E6E763
uniprot id: A0A7E6E768
uniprot id: A0A7E6E773
uniprot id: A0A7E6E7Q3
uniprot id: A0A7E6E7Q7
uniprot id: A0A7E6E7R1
uniprot id: A0A7E6E816
uniprot id: A0A7E6E822
uniprot id: A0A7E6E827
uniprot id: A0A7E6E833
uniprot id: A0A7E6E8L8
uniprot id: A0A7E6E8M4
uniprot id: A0A7E6E8N0
uniprot id: A0A7E6E8N7
uniprot id: A0A7E6E8P2
uniprot id: A0A7E6E8Y7
uniprot id: A0A7E6E8Z1
uniprot id: A0A7E6E8Z7
names: Subcellular Location Annotation
messages: Membrane

89673:SGK2
gene id: 89673:SGK2
uniprot id: A0A6J2MKY9
uniprot id: A0A7E6CFI8
uniprot id: A0A7E6CG48
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:RBFOX1
gene id: 89673:RBFOX1
uniprot id: A0A6J2N033
uniprot id: A0A6J2N038
uniprot id: A0A6J2N0L5
uniprot id: A0A6J2N0N0
uniprot id: A0A7E6D929
uniprot id: A0A7E6D934
uniprot id: A0A7E6D951
uniprot id: A0A7E6D954
uniprot id: A0A7E6D999
uniprot id: A0A7E6D9A5
uniprot id: A0A7E6D9Y4
uniprot id: A0A7E6D9Z1
uniprot id: A0A7E6DC14
uniprot id: A0A7E6DC19
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

89673:EIF4G3
gene id: 89673:EIF4G3
uniprot id: A0A7E6DQ63
uniprot id: A0A7E6DQ68
uniprot id: A0A7E6DQ71
uniprot id: A0A7E6DQ74
uniprot id: A0A7E6DQ75
uniprot id: A0A7E6DQ79
uniprot id: A0A7E6DQ83
uniprot id: A0A7E6DQ88
uniprot id: A0A7E6DQ91
uniprot id: A0A7E6DQ95
uniprot id: A0A7E6DQU7
uniprot id: A0A7E6DQV2
uniprot id: A0A7E6DQW3
uniprot id: A0A7E6DQW6
uniprot id: A0A7E6DQW7
uniprot id: A0A7E6DQX5
uniprot id: A0A7E6DQY0
uniprot id: A0A7E6DQY7
uniprot id: A0A7E6DQZ2
uniprot id: A0A7E6DQZ6
uniprot id: A0A7E6DRB8
uniprot id: A0A7E6DRC1
uniprot id: A0A7E6DRC7
uniprot id: A0A7E6DRD1
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4G family.

89673:CEP170B
gene id: 89673:CEP170B
uniprot id: A0A6J2L4V5
names: Similarity
messages: Belongs to the CEP170 family.

89673:EPB42
gene id: 89673:EPB42
uniprot id: A0A6J2LA85
uniprot id: A0A7E6EA14
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.

89673:LOC114496072
gene id: 89673:LOC114496072
uniprot id: A0A6J2LH65
uniprot id: A0A6J2LJH5
uniprot id: A0A7E6DUQ3
uniprot id: A0A7E6DV69
uniprot id: A0A7E6DVX6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics.
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane
messages: Interacts with chaperones HSP70 and HSP90; this interaction is required for initial targeting to mitochondria.
messages: Membrane
messages: Microsome membrane
messages: Mitochondrion inner membrane
messages: The omega-1 hydroxylase activity is stimulated by cytochrome b5.

89673:ERCC2
gene id: 89673:ERCC2
uniprot id: A0A6J2N776
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Nucleus

89673:SLC27A6
gene id: 89673:SLC27A6
uniprot id: A0A6J2LSS1
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

89673:EIF3A
gene id: 89673:EIF3A
uniprot id: A0A6J2LNC6
uniprot id: A0A7E6DW74
uniprot id: A0A7E6DX08
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit A family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3L and EIF3K. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with EIF4G1. Also interacts with KRT7 and PIWIL2.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.

89673:PHOX2B
gene id: 89673:PHOX2B
uniprot id: A0A6J2L2Y2
names: Subcellular Location Annotation
messages: Nucleus

89673:GTPBP10
gene id: 89673:GTPBP10
uniprot id: A0A6J2MTG9
uniprot id: A0A7E6CHW5
uniprot id: A0A7E6CI73
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

89673:NEDD9
gene id: 89673:NEDD9
uniprot id: A0A6J2LH86
uniprot id: A0A7E6DU01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

89673:GPT
gene id: 89673:GPT
uniprot id: A0A6J2NI26
uniprot id: A0A7E6E8X4
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

89673:HAO1
gene id: 89673:HAO1
uniprot id: A0A6J2MQH2
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

89673:TBR1
gene id: 89673:TBR1
uniprot id: A0A6J2LLU1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

89673:CDC73
gene id: 89673:CDC73
uniprot id: A0A6J2N5C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC73 family.
messages: Nucleus

89673:ABI3
gene id: 89673:ABI3
uniprot id: A0A6J2MBL5
names: Similarity
messages: Belongs to the ABI family.

89673:RAD21L1
gene id: 89673:RAD21L1
uniprot id: A0A6J2MRZ0
uniprot id: A0A7E6CFL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

89673:KCNH3
gene id: 89673:KCNH3
uniprot id: A0A6J2N6L0
uniprot id: A0A7E6D6W7
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

89673:OVOL1
gene id: 89673:OVOL1
uniprot id: A0A6J2LYM7
names: Subcellular Location Annotation
messages: Nucleus

89673:HHEX
gene id: 89673:HHEX
uniprot id: A0A6J2LQB3
names: Subcellular Location Annotation
messages: Nucleus

89673:PSMF1
gene id: 89673:PSMF1
uniprot id: A0A6J2MK82
uniprot id: A0A6J2MRA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proteasome inhibitor PI31 family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28.

89673:LOC118496811
gene id: 89673:LOC118496811
uniprot id: A0A7E6CH71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

89673:AMBN
gene id: 89673:AMBN
uniprot id: A0A6J2L791
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ameloblastin family.
messages: Involved in the mineralization and structural organization of enamel.
messages: extracellular matrix

89673:LIN9
gene id: 89673:LIN9
uniprot id: A0A6J2N5K8
uniprot id: A0A7E6CXY8
names: Similarity
messages: Belongs to the lin-9 family.

89673:MCU
gene id: 89673:MCU
uniprot id: A0A6J2LJY0
uniprot id: A0A6J2LPB0
uniprot id: A0A7E6DU68
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCU (TC 1.A.77) family.
messages: Forms a well-packed pentamer with an overall cylindrical shape. The inner core of the pentamer is formed with the second transmembrane region and the second coiled-coil region: while the transmembrane regions pack into a five-helix bundle having a largely polar pore across the membrane, the coiled-coil outside the membrane forms a pentamer with a hydrophobic core. The inner core is wrapped by the first transmembrane region through contacts between the first and the second transmembrane regions. The second transmembrane is followed by the inner juxtamembrane region (IJMH) that orients at a wide angle relative to the second transmembrane. The two core domains are held together on the periphery by the outer juxtamembrane helix (OJMH).
messages: Membrane
messages: Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
messages: Mitochondrion inner membrane

89673:MYCL
gene id: 89673:MYCL
uniprot id: A0A6J2LUM4
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

89673:EEF1G
gene id: 89673:EEF1G
uniprot id: A0A6J2M1F8
names: Function
names: Subunit
messages: EF-1 is composed of four subunits: alpha, beta, delta, and gamma.
messages: Probably plays a role in anchoring the complex to other cellular components.

89673:BHMT2
gene id: 89673:BHMT2
uniprot id: A0A6J2MQY3
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

89673:DLG1
gene id: 89673:DLG1
uniprot id: A0A6J2L0E0
uniprot id: A0A6J2L200
uniprot id: A0A6J2L3Y9
uniprot id: A0A6J2L5F4
uniprot id: A0A7E6D4I0
uniprot id: A0A7E6D4I4
uniprot id: A0A7E6D4L7
uniprot id: A0A7E6D4M2
uniprot id: A0A7E6D4P9
uniprot id: A0A7E6D574
uniprot id: A0A7E6D7C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: Membrane

89673:ME3
gene id: 89673:ME3
uniprot id: A0A6J2M2T1
uniprot id: A0A7E6E0F6
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

89673:LOC114498634
gene id: 89673:LOC114498634
uniprot id: A0A6J2LWY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:DBNL
gene id: 89673:DBNL
uniprot id: A0A6J2KXN6
uniprot id: A0A6J2L2X2
uniprot id: A0A7E6CHE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABP1 family.
messages: Early endosome
messages: Golgi apparatus membrane
messages: Perikaryon
messages: Postsynaptic density
messages: cell cortex
messages: clathrin-coated vesicle membrane
messages: dendrite
messages: lamellipodium
messages: neuron projection
messages: podosome
messages: ruffle

89673:LOC114512403
gene id: 89673:LOC114512403
uniprot id: A0A7E6CYD4
names: Similarity
messages: Belongs to the CATSPERD family.

89673:YWHAB
gene id: 89673:YWHAB
uniprot id: A0A6J2MJU2
names: Similarity
messages: Belongs to the 14-3-3 family.

89673:CLCA4
gene id: 89673:CLCA4
uniprot id: A0A6J2LPR0
uniprot id: A0A7E6DSU4
names: Similarity
messages: Belongs to the CLCR family.

89673:LOC114498949
gene id: 89673:LOC114498949
uniprot id: A0A6J2LUN8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:HPS6
gene id: 89673:HPS6
uniprot id: A0A6J2LI23
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the biogenesis of lysosome-related organelles complex-2 (or BLOC2) composed of HPS3, HPS5 and HPS6. Interacts with HPS5 and HPS3. Interacts with biogenesis of lysosome-related organelles complex-1 (BLOC1). Interacts with AP-3 complex.
messages: May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.
messages: Microsome membrane

89673:SIVA1
gene id: 89673:SIVA1
uniprot id: A0A6J2LD54
names: Function
names: PTM
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl-x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.
messages: Nucleus
messages: Phosphorylated by ABL2/ARG in response to oxidative stress.

89673:SUGP2
gene id: 89673:SUGP2
uniprot id: A0A6J2M906
names: Subcellular Location Annotation
messages: Nucleus

89673:ABCB7
gene id: 89673:ABCB7
uniprot id: A0A6J2MDG8
names: Subcellular Location Annotation
messages: Membrane

89673:LOC118496637
gene id: 89673:LOC118496637
uniprot id: A0A7E6E496
names: Similarity
messages: Belongs to the FAM178 family.

89673:SETD6
gene id: 89673:SETD6
uniprot id: A0A7E6CLL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily.
messages: Nucleus
messages: Protein-lysine N-methyltransferase.

89673:KCNK17
gene id: 89673:KCNK17
uniprot id: A0A6J2LJC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

89673:IL36RN
gene id: 89673:IL36RN
uniprot id: A0A6J2M2H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens.
messages: Belongs to the IL-1 family.
messages: Secreted

89673:NAV2
gene id: 89673:NAV2
uniprot id: A0A6J2LWL2
uniprot id: A0A6J2LZJ2
uniprot id: A0A6J2M036
uniprot id: A0A7E6E0L1
uniprot id: A0A7E6E1U2
names: Similarity
messages: Belongs to the Nav/unc-53 family.

89673:SNX10
gene id: 89673:SNX10
uniprot id: A0A6J2MTZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

89673:CNN2
gene id: 89673:CNN2
uniprot id: A0A6J2ME07
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

89673:LOC114499756
gene id: 89673:LOC114499756
uniprot id: A0A6J2LXD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LIG1
gene id: 89673:LIG1
uniprot id: A0A7E6CNB9
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.

89673:MAN2A1
gene id: 89673:MAN2A1
uniprot id: A0A6J2LIV2
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

89673:ALG14
gene id: 89673:ALG14
uniprot id: A0A6J2KYT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG14 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane

89673:ENKD1
gene id: 89673:ENKD1
uniprot id: A0A6J2KSL6
uniprot id: A0A7E6CM20
names: Subcellular Location Annotation
messages: cilium axoneme

89673:AFF3
gene id: 89673:AFF3
uniprot id: A0A7E6DZ79
names: Similarity
messages: Belongs to the AF4 family.

89673:SPECC1L
gene id: 89673:SPECC1L
uniprot id: A0A6J2MVP9
uniprot id: A0A7E6CSW6
uniprot id: A0A7E6CSW9
uniprot id: A0A7E6CTD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytospin-A family.
messages: Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration.
messages: May interact with both microtubules and actin cytoskeleton.
messages: cytoskeleton
messages: gap junction
messages: spindle

89673:VPS28
gene id: 89673:VPS28
uniprot id: A0A6J2NCE9
names: Function
names: Similarity
messages: Belongs to the VPS28 family.
messages: Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.

89673:LOC114499122
gene id: 89673:LOC114499122
uniprot id: A0A7E6E3G4
names: Similarity
messages: Belongs to the peptidase A1 family.

89673:NPM1
gene id: 89673:NPM1
uniprot id: A0A6J2MVT1
uniprot id: A0A7E6CRY0
names: Similarity
messages: Belongs to the nucleoplasmin family.

89673:FOLR2
gene id: 89673:FOLR2
uniprot id: A0A6J2M434
uniprot id: A0A7E6E122
names: Similarity
messages: Belongs to the folate receptor family.

89673:LIN7B
gene id: 89673:LIN7B
uniprot id: A0A6J2N106
uniprot id: A0A7E6CQM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the lin-7 family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.
messages: Postsynaptic density membrane
messages: tight junction

89673:GPD1L
gene id: 89673:GPD1L
uniprot id: A0A6J2M3Y3
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

89673:MAPK14
gene id: 89673:MAPK14
uniprot id: A0A6J2LBJ9
uniprot id: A0A6J2LEA4
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

89673:ANTXR2
gene id: 89673:ANTXR2
uniprot id: A0A6J2L3H9
uniprot id: A0A6J2L5F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

89673:LOC114499065
gene id: 89673:LOC114499065
uniprot id: A0A6J2LSU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SLCO3A1
gene id: 89673:SLCO3A1
uniprot id: A0A6J2KSN4
uniprot id: A0A6J2KY35
uniprot id: A0A7E6CPW0
uniprot id: A0A7E6CQ25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

89673:ATG3
gene id: 89673:ATG3
uniprot id: A0A6J2KZ67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG3 family.
messages: Cytoplasm

89673:FAM210B
gene id: 89673:FAM210B
uniprot id: A0A6J2MSB1
names: Similarity
messages: Belongs to the FAM210 family.

89673:FUT9
gene id: 89673:FUT9
uniprot id: A0A6J2LDJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

89673:ATAD2B
gene id: 89673:ATAD2B
uniprot id: A0A6J2LRG3
uniprot id: A0A7E6DWI2
uniprot id: A0A7E6DX26
names: Similarity
messages: Belongs to the AAA ATPase family.

89673:MRPS7
gene id: 89673:MRPS7
uniprot id: A0A6J2MAN9
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

89673:TMEM132C
gene id: 89673:TMEM132C
uniprot id: A0A7E6CXL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

89673:SPPL2A
gene id: 89673:SPPL2A
uniprot id: A0A7E6EE63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Endosome membrane
messages: Lysosome membrane
messages: Membrane

89673:SLC29A2
gene id: 89673:SLC29A2
uniprot id: A0A6J2M1K5
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Basolateral cell membrane
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Lateral cell membrane
messages: Membrane

89673:PLA2G2E
gene id: 89673:PLA2G2E
uniprot id: A0A6J2LVL3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

89673:SPOCK1
gene id: 89673:SPOCK1
uniprot id: A0A6J2N298
uniprot id: A0A6J2N314
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:PTGER3
gene id: 89673:PTGER3
uniprot id: A0A6J2LN33
uniprot id: A0A7E6DSQ5
uniprot id: A0A7E6DTC2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:RANBP6
gene id: 89673:RANBP6
uniprot id: A0A6J2LER6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

89673:KALRN
gene id: 89673:KALRN
uniprot id: A0A6J2KYV8
uniprot id: A0A6J2KZG5
uniprot id: A0A6J2L2W2
uniprot id: A0A7E6D489
uniprot id: A0A7E6D4D6
uniprot id: A0A7E6D4G0
uniprot id: A0A7E6D4Y2
uniprot id: A0A7E6D4Y7
uniprot id: A0A7E6D725
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cytoplasm

89673:GALNT7
gene id: 89673:GALNT7
uniprot id: A0A6J2M4L2
uniprot id: A0A6J2MA82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

89673:AGO3
gene id: 89673:AGO3
uniprot id: A0A6J2LJL0
uniprot id: A0A6J2LLV0
uniprot id: A0A7E6DR17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argonaute family.
messages: Belongs to the argonaute family. Ago subfamily.
messages: Interacts with EIF4B, IMP8, PRMT5 and TNRC6B. Interacts with APOBEC3F, APOBEC3G and APOBEC3H.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.

89673:RNASEH2A
gene id: 89673:RNASEH2A
uniprot id: A0A6J2M7G2
uniprot id: A0A7E6EAC5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family. Eukaryotic subfamily.
messages: Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

89673:PPP1R12B
gene id: 89673:PPP1R12B
uniprot id: A0A7E6CYF4
names: Subcellular Location Annotation
names: Subunit
messages: PP1 comprises a catalytic subunit, and one or several targeting or regulatory subunits.
messages: stress fiber

89673:LOC114496544
gene id: 89673:LOC114496544
uniprot id: A0A6J2LQ06
uniprot id: A0A7E6DQM1
uniprot id: A0A7E6DRC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TRSPAP family.
messages: Cytoplasm
messages: Involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins. Stabilizes the SECISBP2, EEFSEC and tRNA(Sec) complex. May be involved in the methylation of tRNA(Sec). Enhances efficiency of selenoproteins synthesis.
messages: Nucleus

89673:ASL
gene id: 89673:ASL
uniprot id: A0A6J2LUL3
names: Similarity
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

89673:NME5
gene id: 89673:NME5
uniprot id: A0A6J2N340
names: Similarity
messages: Belongs to the NDK family.

89673:NSUN7
gene id: 89673:NSUN7
uniprot id: A0A6J2L4R5
uniprot id: A0A7E6D9L8
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:CPQ
gene id: 89673:CPQ
uniprot id: A0A6J2NIR4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Carboxypeptidase that may play an important role in the hydrolysis of circulating peptides. Catalyzes the hydrolysis of dipeptides with unsubstituted terminals into amino acids. May play a role in the liberation of thyroxine hormone from its thyroglobulin (Tg) precursor.
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer. The monomeric form is inactive while the homodimer is active.
messages: Lysosome

89673:LOC114490700
gene id: 89673:LOC114490700
uniprot id: A0A6J2L0Y7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Cytoplasm
messages: Monomer.

89673:NONO
gene id: 89673:NONO
uniprot id: A0A6J2MFL8
names: Subcellular Location Annotation
messages: Nucleus speckle

89673:LOC114511308
gene id: 89673:LOC114511308
uniprot id: A0A6J2N787
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lambda interferon family.
messages: Secreted

89673:SLC12A1
gene id: 89673:SLC12A1
uniprot id: A0A6J2L8D9
uniprot id: A0A6J2LCD3
uniprot id: A0A7E6EDH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

89673:NOP2
gene id: 89673:NOP2
uniprot id: A0A6J2N6L4
uniprot id: A0A7E6D2M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: nucleolus

89673:GLYATL2
gene id: 89673:GLYATL2
uniprot id: A0A6J2M1Q8
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

89673:STARD3NL
gene id: 89673:STARD3NL
uniprot id: A0A6J2MNY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STARD3 family.
messages: Membrane

89673:SSRP1
gene id: 89673:SSRP1
uniprot id: A0A6J2LUU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSRP1 family.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Nucleus

89673:TM4SF1
gene id: 89673:TM4SF1
uniprot id: A0A6J2L2C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

89673:ADCYAP1
gene id: 89673:ADCYAP1
uniprot id: A0A6J2MMY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

89673:LOC114496153
gene id: 89673:LOC114496153
uniprot id: A0A7E6DP74
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

89673:P2RY4
gene id: 89673:P2RY4
uniprot id: A0A6J2MFX5
uniprot id: A0A7E6CZB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:USP1
gene id: 89673:USP1
uniprot id: A0A6J2LH26
uniprot id: A0A6J2LMR6
uniprot id: A0A7E6DSA9
uniprot id: A0A7E6DT41
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

89673:LOC114512674
gene id: 89673:LOC114512674
uniprot id: A0A7E6D7R7
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

89673:CHN1
gene id: 89673:CHN1
uniprot id: A0A6J2LCX7
uniprot id: A0A7E6DJJ6
names: Function
messages: GTPase-activating protein for p21-rac.

89673:FUCA2
gene id: 89673:FUCA2
uniprot id: A0A6J2LEJ5
names: Function
names: Similarity
names: Subunit
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
messages: Belongs to the glycosyl hydrolase 29 family.
messages: Homotetramer.

89673:LOC114504890
gene id: 89673:LOC114504890
uniprot id: A0A6J2MK45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

89673:RPLP1
gene id: 89673:RPLP1
uniprot id: A0A6J2L975
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

89673:LOC114511428
gene id: 89673:LOC114511428
uniprot id: A0A7E6CTJ0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

89673:LOC114514997
gene id: 89673:LOC114514997
uniprot id: A0A7E6DFZ8
uniprot id: A0A7E6DG03
uniprot id: A0A7E6DG14
uniprot id: A0A7E6DG57
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

89673:TMED3
gene id: 89673:TMED3
uniprot id: A0A6J2KSG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

89673:DYNC1I1
gene id: 89673:DYNC1I1
uniprot id: A0A7E6CJR2
names: Similarity
messages: Belongs to the dynein intermediate chain family.

89673:XDH
gene id: 89673:XDH
uniprot id: A0A6J2LYC0
uniprot id: A0A7E6DWT9
uniprot id: A0A7E6DXT4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Homodimer. Interacts with BTN1A1.
messages: Peroxisome

89673:LOC114502299
gene id: 89673:LOC114502299
uniprot id: A0A6J2M9F1
names: Subcellular Location Annotation
messages: Membrane

89673:SOX3
gene id: 89673:SOX3
uniprot id: A0A6J2MMC9
names: Subcellular Location Annotation
messages: Nucleus

89673:MC4R
gene id: 89673:MC4R
uniprot id: A0A6J2MK77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).

89673:ABRACL
gene id: 89673:ABRACL
uniprot id: A0A6J2LGT9
names: Similarity
messages: Belongs to the costars family.

89673:DIPK1A
gene id: 89673:DIPK1A
uniprot id: A0A6J2LHH2
names: Similarity
messages: Belongs to the DIPK family.

89673:PITX3
gene id: 89673:PITX3
uniprot id: A0A6J2LUS0
names: Subcellular Location Annotation
messages: Nucleus

89673:BSCL2
gene id: 89673:BSCL2
uniprot id: A0A6J2M1M8
uniprot id: A0A7E6E1S2
uniprot id: A0A7E6E1S7
uniprot id: A0A7E6E2A8
uniprot id: A0A7E6E2H1
uniprot id: A0A7E6E368
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:LOC114508583
gene id: 89673:LOC114508583
uniprot id: A0A6J2MWZ0
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.

89673:KRT8
gene id: 89673:KRT8
uniprot id: A0A6J2N9S9
names: Similarity
messages: Belongs to the intermediate filament family.

89673:LOC114507007
gene id: 89673:LOC114507007
uniprot id: A0A7E6CDK6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS19 family.

89673:PMS2
gene id: 89673:PMS2
uniprot id: A0A6J2MWF0
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

89673:GMPR
gene id: 89673:GMPR
uniprot id: A0A6J2LPR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

89673:MAP3K6
gene id: 89673:MAP3K6
uniprot id: A0A6J2LNG2
uniprot id: A0A6J2LTX1
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

89673:GAS8
gene id: 89673:GAS8
uniprot id: A0A6J2KZ03
uniprot id: A0A7E6CQB4
uniprot id: A0A7E6CSV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC4 family.
messages: flagellum
messages: flagellum axoneme

89673:KMT2A
gene id: 89673:KMT2A
uniprot id: A0A7E6DYU3
uniprot id: A0A7E6DZQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.
messages: Nucleus

89673:MYO10
gene id: 89673:MYO10
uniprot id: A0A6J2N2T4
uniprot id: A0A6J2N4J0
uniprot id: A0A7E6DAA5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

89673:PPM1B
gene id: 89673:PPM1B
uniprot id: A0A6J2LY37
uniprot id: A0A6J2LZ71
uniprot id: A0A6J2M3L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

89673:LOC114502151
gene id: 89673:LOC114502151
uniprot id: A0A6J2M5P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

89673:ODF2L
gene id: 89673:ODF2L
uniprot id: A0A7E6DSU0
uniprot id: A0A7E6DTF2
uniprot id: A0A7E6DTF7
uniprot id: A0A7E6DTL4
uniprot id: A0A7E6DU04
uniprot id: A0A7E6DU09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

89673:LOC114500877
gene id: 89673:LOC114500877
uniprot id: A0A6J2M1J2
names: Subcellular Location Annotation
messages: Membrane

89673:CLDN8
gene id: 89673:CLDN8
uniprot id: A0A6J2L0E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

89673:LTB4R
gene id: 89673:LTB4R
uniprot id: A0A6J2L8X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

89673:MOGAT2
gene id: 89673:MOGAT2
uniprot id: A0A6J2M2E7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:GBE1
gene id: 89673:GBE1
uniprot id: A0A7E6D472
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

89673:B3GAT2
gene id: 89673:B3GAT2
uniprot id: A0A6J2LCI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

89673:LOC114512462
gene id: 89673:LOC114512462
uniprot id: A0A7E6D0T3
names: Similarity
messages: Belongs to the peptidase C2 family.

89673:LOC114507464
gene id: 89673:LOC114507464
uniprot id: A0A7E6CIZ8
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

89673:CAPN7
gene id: 89673:CAPN7
uniprot id: A0A6J2M422
uniprot id: A0A7E6E4L1
names: Similarity
messages: Belongs to the peptidase C2 family.

89673:PDS5B
gene id: 89673:PDS5B
uniprot id: A0A6J2MSP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDS5 family.
messages: Nucleus

89673:UBE2T
gene id: 89673:UBE2T
uniprot id: A0A7E6CY31
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

89673:C3H9orf78
gene id: 89673:C3H9orf78
uniprot id: A0A6J2MCI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TLS1 family.
messages: Nucleus

89673:WSCD2
gene id: 89673:WSCD2
uniprot id: A0A6J2N1L5
names: Function
names: Similarity
messages: Belongs to the WSCD family.
messages: Sialate:O-sulfotransferase which catalyzes 8-O-sulfation at the Sia-glycan level using 3'-phosphoadenosine 5'-phosphosulfate (PAPS) as a donor, forming 8-O-sulfated Sia (Sia8S)-glycans.

89673:DBT
gene id: 89673:DBT
uniprot id: A0A6J2KVP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Mitochondrion matrix

89673:LOC114500149
gene id: 89673:LOC114500149
uniprot id: A0A7E6E034
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:NGF
gene id: 89673:NGF
uniprot id: A0A6J2KZA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Secreted

89673:LZIC
gene id: 89673:LZIC
uniprot id: A0A6J2LTN9
names: Similarity
messages: Belongs to the CTNNBIP1 family.

89673:LOC118500744
gene id: 89673:LOC118500744
uniprot id: A0A7E6DTH5
uniprot id: A0A7E6DU55
uniprot id: A0A7E6DUK5
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

89673:SBF2
gene id: 89673:SBF2
uniprot id: A0A6J2LSC0
uniprot id: A0A7E6E1I3
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

89673:CEP290
gene id: 89673:CEP290
uniprot id: A0A6J2NAW3
uniprot id: A0A7E6D5D8
uniprot id: A0A7E6D5F2
uniprot id: A0A7E6D628
names: Subcellular Location Annotation
messages: cilium basal body

89673:PRKCH
gene id: 89673:PRKCH
uniprot id: A0A6J2LAB6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentiation. Associates with the cyclin CCNE1-CDK2-CDKN1B complex and inhibits CDK2 kinase activity, leading to RB1 dephosphorylation and thereby G1 arrest in keratinocytes. In association with RALA activates actin depolymerization, which is necessary for keratinocyte differentiation. In the pre-B cell receptor signaling, functions downstream of BLNK by up-regulating IRF4, which in turn activates L chain gene rearrangement. Regulates epithelial tight junctions (TJs) by phosphorylating occludin (OCLN) on threonine residues, which is necessary for the assembly and maintenance of TJs. In association with PLD2 and via TLR4 signaling, is involved in lipopolysaccharide (LPS)-induced RGS2 down-regulation and foam cell formation. Upon PMA stimulation, mediates glioblastoma cell proliferation by activating the mTOR pathway, the PI3K/AKT pathway and the ERK1-dependent phosphorylation of ELK1. Involved in the protection of glioblastoma cells from irradiation-induced apoptosis by preventing caspase-9 activation. In camptothecin-treated MCF-7 cells, regulates NF-kappa-B upstream signaling by activating IKBKB, and confers protection against DNA damage-induced apoptosis.
messages: Cytoplasm
messages: Novel PKCs (PRKCD, PRKCE, PRKCH and PRKCQ) are calcium-insensitive, but activated by diacylglycerol (DAG) and phosphatidylserine. Three specific sites; Thr-513 (activation loop of the kinase domain), Thr-656 (turn motif) and Ser-675 (hydrophobic region), need to be phosphorylated for its full activation.

89673:ANKH
gene id: 89673:ANKH
uniprot id: A0A6J2LMC0
uniprot id: A0A7E6DCX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKH family.
messages: Membrane
messages: Regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter.

89673:WDR12
gene id: 89673:WDR12
uniprot id: A0A7E6DIX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat WDR12/YTM1 family.
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

89673:MPDU1
gene id: 89673:MPDU1
uniprot id: A0A6J2NE74
uniprot id: A0A7E6EBH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPDU1 (TC 2.A.43.3) family.
messages: Membrane
messages: Required for normal utilization of mannose-dolichol phosphate (Dol-P-Man) in the synthesis of N-linked and O-linked oligosaccharides and GPI anchors.

89673:LIX1
gene id: 89673:LIX1
uniprot id: A0A6J2LQI9
uniprot id: A0A7E6DBA4
names: Similarity
messages: Belongs to the LIX1 family.

89673:IK
gene id: 89673:IK
uniprot id: A0A6J2N018
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RED family.
messages: Nucleus

89673:C3H16orf71
gene id: 89673:C3H16orf71
uniprot id: A0A6J2M6C9
uniprot id: A0A7E6DBV4
uniprot id: A0A7E6DBV8
uniprot id: A0A7E6DC44
uniprot id: A0A7E6DCH7
uniprot id: A0A7E6DD12
uniprot id: A0A7E6DDL1
uniprot id: A0A7E6DDL2
names: Function
names: Subcellular Location Annotation
messages: Dynein axonemal particle
messages: In cyliated cells, dynein axonemal particle-specific protein required for deployment of ODA to the axoneme. Interacts with outer dynein arm (ODA) subunits.

89673:DPP4
gene id: 89673:DPP4
uniprot id: A0A7E6DJX9
names: Subcellular Location Annotation
messages: Cell membrane
messages: invadopodium membrane
messages: lamellipodium membrane

89673:GNG7
gene id: 89673:GNG7
uniprot id: A0A6J2MBK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

89673:DLGAP4
gene id: 89673:DLGAP4
uniprot id: A0A6J2MHH2
uniprot id: A0A6J2MNS2
uniprot id: A0A7E6CFD3
uniprot id: A0A7E6CFZ5
names: Similarity
messages: Belongs to the SAPAP family.

89673:MED28
gene id: 89673:MED28
uniprot id: A0A6J2LAI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 28 family.
messages: Nucleus

89673:NPFFR2
gene id: 89673:NPFFR2
uniprot id: A0A6J2L8C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

89673:TCFL5
gene id: 89673:TCFL5
uniprot id: A0A6J2ML89
uniprot id: A0A6J2MQJ6
names: Subcellular Location Annotation
messages: Nucleus

89673:CHST3
gene id: 89673:CHST3
uniprot id: A0A6J2LK07
uniprot id: A0A7E6DV10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

89673:NAT9
gene id: 89673:NAT9
uniprot id: A0A6J2M9L6
uniprot id: A0A7E6EEH1
names: Similarity
messages: Belongs to the acetyltransferase family. GNAT subfamily.

89673:LOC114510844
gene id: 89673:LOC114510844
uniprot id: A0A7E6CT62
names: Similarity
messages: Belongs to the MHC class I family.

89673:UPF3A
gene id: 89673:UPF3A
uniprot id: A0A6J2MT09
uniprot id: A0A6J2MT16
uniprot id: A0A7E6CKH0
uniprot id: A0A7E6CKH3
uniprot id: A0A7E6CMJ5
names: Similarity
messages: Belongs to the RENT3 family.

89673:LOC114492693
gene id: 89673:LOC114492693
uniprot id: A0A7E6CFM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIIc family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits, encoded in the mitochondrial DNA, and 11 supernumerary subunits, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

89673:NGDN
gene id: 89673:NGDN
uniprot id: A0A6J2L878
uniprot id: A0A6J2LDH9
uniprot id: A0A7E6E3F7
names: Subcellular Location Annotation
messages: nucleolus

89673:NOTCH4
gene id: 89673:NOTCH4
uniprot id: A0A7E6DLC2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

89673:SLC8A1
gene id: 89673:SLC8A1
uniprot id: A0A6J2LT64
uniprot id: A0A6J2LT70
uniprot id: A0A6J2LW70
uniprot id: A0A7E6DX91
uniprot id: A0A7E6DX95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

89673:LOC114496360
gene id: 89673:LOC114496360
uniprot id: A0A6J2LN54
names: Similarity
messages: Belongs to the cytochrome P450 family.

89673:MBTPS2
gene id: 89673:MBTPS2
uniprot id: A0A6J2MJ55
names: Similarity
messages: Belongs to the peptidase M50A family.

89673:BORCS8
gene id: 89673:BORCS8
uniprot id: A0A6J2M7C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS8 family.
messages: Lysosome membrane
messages: Membrane

89673:SNRPA1
gene id: 89673:SNRPA1
uniprot id: A0A7E6CRG0
names: Similarity
messages: Belongs to the U2 small nuclear ribonucleoprotein A family.

89673:TXLNB
gene id: 89673:TXLNB
uniprot id: A0A6J2LHH5
names: Similarity
messages: Belongs to the taxilin family.

89673:PLK5
gene id: 89673:PLK5
uniprot id: A0A7E6E8P9
uniprot id: A0A7E6E9P9
uniprot id: A0A7E6E9Q5
uniprot id: A0A7E6EAB9
uniprot id: A0A7E6EAC3
names: Similarity
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

89673:TBX3
gene id: 89673:TBX3
uniprot id: A0A6J2MU43
uniprot id: A0A6J2N0C0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

89673:SLC34A2
gene id: 89673:SLC34A2
uniprot id: A0A7E6D855
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Membrane

89673:HMGN2
gene id: 89673:HMGN2
uniprot id: A0A6J2LLX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

89673:HAUS3
gene id: 89673:HAUS3
uniprot id: A0A6J2L1X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS3 family.
messages: spindle

89673:LOC118498402
gene id: 89673:LOC118498402
uniprot id: A0A7E6CZ30
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

89673:ZDHHC1
gene id: 89673:ZDHHC1
uniprot id: A0A6J2KTV3
uniprot id: A0A7E6CLT4
uniprot id: A0A7E6CLU5
uniprot id: A0A7E6CLW1
uniprot id: A0A7E6CLZ6
uniprot id: A0A7E6CP17
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

89673:SCRIB
gene id: 89673:SCRIB
uniprot id: A0A7E6E7A0
uniprot id: A0A7E6E7A3
uniprot id: A0A7E6E7U0
uniprot id: A0A7E6E7U3
uniprot id: A0A7E6E858
uniprot id: A0A7E6E861
uniprot id: A0A7E6E8R9
uniprot id: A0A7E6E8S3
uniprot id: A0A7E6E934
names: Similarity
messages: Belongs to the LAP (LRR and PDZ) protein family.

89673:SMG1
gene id: 89673:SMG1
uniprot id: A0A6J2MY23
uniprot id: A0A7E6DC76
names: Similarity
messages: Belongs to the PI3/PI4-kinase family.

89673:B4GALT5
gene id: 89673:B4GALT5
uniprot id: A0A6J2MPR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

89673:LOC114511087
gene id: 89673:LOC114511087
uniprot id: A0A6J2N105
uniprot id: A0A6J2N5P7
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.

89673:AP2S1
gene id: 89673:AP2S1
uniprot id: A0A6J2N589
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cell membrane
messages: coated pit

89673:ADGB
gene id: 89673:ADGB
uniprot id: A0A7E6DNL9
uniprot id: A0A7E6DP38
uniprot id: A0A7E6DPA0
uniprot id: A0A7E6DPL9
names: Caution
names: Similarity
messages: Belongs to the peptidase C2 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114498646
gene id: 89673:LOC114498646
uniprot id: A0A6J2LU23
uniprot id: A0A7E6E0F5
names: Subcellular Location Annotation
messages: Cytoplasm

89673:LOC114500191
gene id: 89673:LOC114500191
uniprot id: A0A6J2LY03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:MED8
gene id: 89673:MED8
uniprot id: A0A6J2LU26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 8 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

89673:LOC114503653
gene id: 89673:LOC114503653
uniprot id: A0A7E6E971
names: Subcellular Location Annotation
messages: Secreted

89673:USP11
gene id: 89673:USP11
uniprot id: A0A7E6CZ15
uniprot id: A0A7E6CZ18
uniprot id: A0A7E6CZF8
uniprot id: A0A7E6CZG2
uniprot id: A0A7E6CZZ1
uniprot id: A0A7E6D1N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

89673:LOC114501611
gene id: 89673:LOC114501611
uniprot id: A0A6J2M3G1
names: Similarity
messages: Belongs to the transferrin family.

89673:HOXB13
gene id: 89673:HOXB13
uniprot id: A0A6J2MD50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

89673:BST1
gene id: 89673:BST1
uniprot id: A0A6J2LA94
names: Similarity
messages: Belongs to the ADP-ribosyl cyclase family.

89673:DHX15
gene id: 89673:DHX15
uniprot id: A0A6J2L511
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.

89673:LOC114500434
gene id: 89673:LOC114500434
uniprot id: A0A7E6E425
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114498876
gene id: 89673:LOC114498876
uniprot id: A0A6J2LUJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TAS2R10
gene id: 89673:TAS2R10
uniprot id: A0A6J2NFU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

89673:EIF4E2
gene id: 89673:EIF4E2
uniprot id: A0A6J2LBA4
uniprot id: A0A6J2LH39
uniprot id: A0A7E6DHT9
uniprot id: A0A7E6DHW1
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

89673:CCDC167
gene id: 89673:CCDC167
uniprot id: A0A6J2LER7
uniprot id: A0A7E6DLF0
uniprot id: A0A7E6DM59
names: Subcellular Location Annotation
messages: Membrane

89673:HGS
gene id: 89673:HGS
uniprot id: A0A6J2M9Q6
uniprot id: A0A6J2MBQ7
uniprot id: A0A6J2MF43
uniprot id: A0A7E6EFG7
uniprot id: A0A7E6EFT2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Early endosome membrane
messages: Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin-coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes. May contribute to the efficient recruitment of SMADs to the activin receptor complex. Involved in receptor recycling via its association with the CART complex, a multiprotein complex required for efficient transferrin receptor recycling but not for EGFR degradation.
messages: multivesicular body membrane

89673:CPEB4
gene id: 89673:CPEB4
uniprot id: A0A6J2MUG8
uniprot id: A0A6J2MUI4
uniprot id: A0A6J2MZ32
uniprot id: A0A6J2MZJ9
names: Similarity
messages: Belongs to the RRM CPEB family.

89673:SLC2A7
gene id: 89673:SLC2A7
uniprot id: A0A7E6DQ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane

89673:PRDX6
gene id: 89673:PRDX6
uniprot id: A0A6J2N8M5
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

89673:HDAC6
gene id: 89673:HDAC6
uniprot id: A0A6J2MDP3
uniprot id: A0A6J2MFU1
names: Similarity
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.

89673:AFG3L2
gene id: 89673:AFG3L2
uniprot id: A0A6J2MIF0
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

89673:MYO16
gene id: 89673:MYO16
uniprot id: A0A7E6CK98
uniprot id: A0A7E6CKB5
uniprot id: A0A7E6CKC2
uniprot id: A0A7E6CMD5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

89673:KCNT2
gene id: 89673:KCNT2
uniprot id: A0A6J2N599
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:GET4
gene id: 89673:GET4
uniprot id: A0A6J2MYP1
names: Similarity
messages: Belongs to the GET4 family.

89673:EFHB
gene id: 89673:EFHB
uniprot id: A0A6J2M3Q6
names: Subcellular Location Annotation
messages: cilium axoneme

89673:TMEM87A
gene id: 89673:TMEM87A
uniprot id: A0A6J2L820
uniprot id: A0A6J2L997
uniprot id: A0A6J2LDC4
uniprot id: A0A7E6EA85
uniprot id: A0A7E6EAK8
names: Subcellular Location Annotation
messages: Membrane

89673:MRPL53
gene id: 89673:MRPL53
uniprot id: A0A6J2M292
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL53 family.
messages: Mitochondrion

89673:LOC114505542
gene id: 89673:LOC114505542
uniprot id: A0A7E6D1B4
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

89673:NRCAM
gene id: 89673:NRCAM
uniprot id: A0A6J2MNW0
uniprot id: A0A6J2MNW4
uniprot id: A0A6J2MNZ6
uniprot id: A0A6J2MTA3
uniprot id: A0A6J2MTH8
uniprot id: A0A7E6CI98
uniprot id: A0A7E6CIA2
uniprot id: A0A7E6CIC5
uniprot id: A0A7E6CID0
uniprot id: A0A7E6CIJ9
uniprot id: A0A7E6CIK3
uniprot id: A0A7E6CIK8
uniprot id: A0A7E6CIN4
uniprot id: A0A7E6CIN8
uniprot id: A0A7E6CKD4
uniprot id: A0A7E6CKD8
names: Similarity
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.

89673:SNX2
gene id: 89673:SNX2
uniprot id: A0A6J2LB61
uniprot id: A0A6J2LF72
uniprot id: A0A6J2LG90
uniprot id: A0A7E6DBL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: lamellipodium

89673:LRP1B
gene id: 89673:LRP1B
uniprot id: A0A7E6DK23
names: Caution
names: Similarity
messages: Belongs to the LDLR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC118499907
gene id: 89673:LOC118499907
uniprot id: A0A7E6DH95
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

89673:RFC5
gene id: 89673:RFC5
uniprot id: A0A6J2N3U8
names: Similarity
messages: Belongs to the activator 1 small subunits family.

89673:ADGRD1
gene id: 89673:ADGRD1
uniprot id: A0A7E6CRN5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:SIX3
gene id: 89673:SIX3
uniprot id: A0A6J2M5D5
uniprot id: A0A7E6DXP3
names: Subcellular Location Annotation
messages: Nucleus

89673:SNX30
gene id: 89673:SNX30
uniprot id: A0A6J2LVC1
names: Similarity
messages: Belongs to the sorting nexin family.

89673:LOC114489859
gene id: 89673:LOC114489859
uniprot id: A0A6J2L1M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

89673:LOC118500995
gene id: 89673:LOC118500995
uniprot id: A0A7E6DWB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:DCBLD1
gene id: 89673:DCBLD1
uniprot id: A0A6J2LH00
uniprot id: A0A7E6DMX8
uniprot id: A0A7E6DNI2
uniprot id: A0A7E6DNW1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:GADD45A
gene id: 89673:GADD45A
uniprot id: A0A6J2LTL1
names: Similarity
messages: Belongs to the GADD45 family.

89673:BAZ2A
gene id: 89673:BAZ2A
uniprot id: A0A6J2N4V1
uniprot id: A0A6J2N6L6
uniprot id: A0A6J2NC26
uniprot id: A0A6J2NC34
uniprot id: A0A7E6D5Y0
names: Similarity
messages: Belongs to the WAL family.

89673:UFL1
gene id: 89673:UFL1
uniprot id: A0A6J2LAZ9
names: Similarity
messages: Belongs to the UFL1 family.

89673:NCBP2
gene id: 89673:NCBP2
uniprot id: A0A6J2L0U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRM NCBP2 family.
messages: Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U snRNA and intronless mRNAs export from the nucleus. The CBC complex is essential for a pioneer round of mRNA translation, before steady state translation when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. The pioneer round of mRNA translation mediated by the CBC complex plays a central role in nonsense-mediated mRNA decay (NMD), NMD only taking place in mRNAs bound to the CBC complex, but not on eIF4E-bound mRNAs. The CBC complex enhances NMD in mRNAs containing at least one exon-junction complex (EJC), promoting the interaction between upf1 and upf2. The CBC complex is also involved in 'failsafe' NMD, which is independent of the EJC complex, while it does not participate in Staufen-mediated mRNA decay (SMD). During cell proliferation, the CBC complex is also involved in microRNAs (miRNAs) biogenesis via its interaction with srrt/ars2, thereby being required for miRNA-mediated RNA interference. The CBC complex also acts as a negative regulator of parn, thereby acting as an inhibitor of mRNA deadenylation. In the CBC complex, ncbp2/cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp1/cbp80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure. The conventional cap-binding complex with NCBP2 binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus.
messages: Component of the nuclear cap-binding complex (CBC), a heterodimer composed of ncbp1/cbp80 and ncbp2/cbp20 that interacts with m7GpppG-capped RNA.
messages: Nucleus

89673:LOC118498569
gene id: 89673:LOC118498569
uniprot id: A0A7E6D1H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGR2 family.
messages: Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.
messages: Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation.
messages: Mitochondrion inner membrane

89673:C10H7orf25
gene id: 89673:C10H7orf25
uniprot id: A0A6J2MNX1
names: Similarity
messages: Belongs to the UPF0415 family.

89673:DESI2
gene id: 89673:DESI2
uniprot id: A0A6J2N554
uniprot id: A0A6J2N9R4
names: Similarity
messages: Belongs to the DeSI family.

89673:DLGAP2
gene id: 89673:DLGAP2
uniprot id: A0A7E6CJA0
names: Similarity
messages: Belongs to the SAPAP family.

89673:TCF25
gene id: 89673:TCF25
uniprot id: A0A6J2KXC3
uniprot id: A0A6J2KZ19
uniprot id: A0A7E6CQB9
names: Similarity
messages: Belongs to the TCF25 family.

89673:LOC114504819
gene id: 89673:LOC114504819
uniprot id: A0A7E6D156
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

89673:COPS6
gene id: 89673:COPS6
uniprot id: A0A6J2MNQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M67A family. CSN6 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.
messages: Cytoplasm
messages: Nucleus

89673:LOC114515409
gene id: 89673:LOC114515409
uniprot id: A0A6J2NFD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SEM1
gene id: 89673:SEM1
uniprot id: A0A6J2MPP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DSS1/SEM1 family.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Nucleus

89673:ADAMTS8
gene id: 89673:ADAMTS8
uniprot id: A0A6J2MX11
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

89673:NLE1
gene id: 89673:NLE1
uniprot id: A0A6J2MC64
uniprot id: A0A7E6EEX4
names: Subcellular Location Annotation
messages: nucleolus

89673:LOC114513026
gene id: 89673:LOC114513026
uniprot id: A0A6J2N5Z5
names: Similarity
messages: Belongs to the intermediate filament family.

89673:NAALAD2
gene id: 89673:NAALAD2
uniprot id: A0A6J2LVG6
uniprot id: A0A7E6E0N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

89673:GRM7
gene id: 89673:GRM7
uniprot id: A0A6J2M9L8
uniprot id: A0A7E6E5Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

89673:LDHA
gene id: 89673:LDHA
uniprot id: A0A6J2LZU4
uniprot id: A0A7E6E133
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

89673:PI4K2A
gene id: 89673:PI4K2A
uniprot id: A0A6J2LSS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
messages: Membrane

89673:LOC114496648
gene id: 89673:LOC114496648
uniprot id: A0A7E6DT25
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL29 family.

89673:FAM189A2
gene id: 89673:FAM189A2
uniprot id: A0A6J2LZ37
names: Similarity
messages: Belongs to the ENTREP family.

89673:LOC114506046
gene id: 89673:LOC114506046
uniprot id: A0A6J2MJ44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cystatin family.
messages: Secreted

89673:SDC4
gene id: 89673:SDC4
uniprot id: A0A6J2MKL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

89673:AQP4
gene id: 89673:AQP4
uniprot id: A0A6J2MMP6
uniprot id: A0A6J2MRW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

89673:NSMCE2
gene id: 89673:NSMCE2
uniprot id: A0A6J2ND57
uniprot id: A0A7E6E7E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NSE2 family.
messages: Nucleus

89673:PIK3R1
gene id: 89673:PIK3R1
uniprot id: A0A6J2M0P0
uniprot id: A0A6J2M2S7
uniprot id: A0A6J2M675
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

89673:SEMA6A
gene id: 89673:SEMA6A
uniprot id: A0A6J2L0T4
uniprot id: A0A6J2L4I3
uniprot id: A0A6J2L5U9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:MYD88
gene id: 89673:MYD88
uniprot id: A0A6J2M3C2
uniprot id: A0A6J2M7J6
uniprot id: A0A7E6E5Z7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
messages: Cytoplasm
messages: Homodimer. Also forms heterodimers with TIRAP. Binds to TLR2, TLR4, IRAK1, IRAK2 and IRAK4 via their respective TIR domains.

89673:SRP19
gene id: 89673:SRP19
uniprot id: A0A6J2LAL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP19 family.
messages: Cytoplasm

89673:LOC114509253
gene id: 89673:LOC114509253
uniprot id: A0A6J2MT69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

89673:MED13
gene id: 89673:MED13
uniprot id: A0A6J2M5W1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

89673:HOXA6
gene id: 89673:HOXA6
uniprot id: A0A6J2MPF7
uniprot id: A0A6J2MTS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

89673:ISG15
gene id: 89673:ISG15
uniprot id: A0A6J2LR51
names: Subcellular Location Annotation
messages: cytosol

89673:DUSP10
gene id: 89673:DUSP10
uniprot id: A0A6J2N5U9
uniprot id: A0A7E6CYW4
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

89673:PSMD2
gene id: 89673:PSMD2
uniprot id: A0A6J2KUT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S2 family.
messages: Binds to the intracellular domain of tumor necrosis factor type 1 receptor. The binding domain of TRAP1 and TRAP2 resides outside the death domain of TNFR1.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

89673:PRC1
gene id: 89673:PRC1
uniprot id: A0A6J2KRF4
uniprot id: A0A6J2KS07
uniprot id: A0A6J2KXJ9
uniprot id: A0A7E6CMR7
names: Similarity
messages: Belongs to the MAP65/ASE1 family.

89673:PDSS2
gene id: 89673:PDSS2
uniprot id: A0A6J2LDN1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

89673:NMNAT2
gene id: 89673:NMNAT2
uniprot id: A0A6J2N998
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

89673:LOC114489407
gene id: 89673:LOC114489407
uniprot id: A0A6J2L0P7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:ACTL9
gene id: 89673:ACTL9
uniprot id: A0A7E6EH50
names: Similarity
messages: Belongs to the actin family.

89673:CSRNP2
gene id: 89673:CSRNP2
uniprot id: A0A6J2N5W2
uniprot id: A0A7E6D6L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

89673:IL3RA
gene id: 89673:IL3RA
uniprot id: A0A7E6D4B0
names: Subcellular Location Annotation
messages: Membrane

89673:C9H20orf27
gene id: 89673:C9H20orf27
uniprot id: A0A6J2MMN8
names: Similarity
messages: Belongs to the ADISSP family.

89673:F13A1
gene id: 89673:F13A1
uniprot id: A0A6J2LRV5
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

89673:LOC114503991
gene id: 89673:LOC114503991
uniprot id: A0A6J2MBF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

89673:SLC25A43
gene id: 89673:SLC25A43
uniprot id: A0A6J2MGE8
uniprot id: A0A7E6D0X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

89673:KDELR1
gene id: 89673:KDELR1
uniprot id: A0A6J2N198
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:TGM2
gene id: 89673:TGM2
uniprot id: A0A6J2MPY6
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

89673:LOC114495689
gene id: 89673:LOC114495689
uniprot id: A0A7E6DL03
uniprot id: A0A7E6DLC4
uniprot id: A0A7E6DLF5
uniprot id: A0A7E6DLQ6
names: Similarity
messages: Belongs to the MHC class II family.

89673:PTPRN
gene id: 89673:PTPRN
uniprot id: A0A6J2LDT3
uniprot id: A0A6J2LIJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily.
messages: Membrane
messages: secretory vesicle membrane

89673:GRPEL2
gene id: 89673:GRPEL2
uniprot id: A0A6J2N3R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

89673:LNPK
gene id: 89673:LNPK
uniprot id: A0A6J2LHM8
uniprot id: A0A7E6DJB0
uniprot id: A0A7E6DJJ1
uniprot id: A0A7E6DJQ0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Homodimer; homodimerization requires the C4-type zinc finger motif and decreases during mitosis in a phosphorylation-dependent manner.
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

89673:GREM2
gene id: 89673:GREM2
uniprot id: A0A6J2NAU4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:HOXB9
gene id: 89673:HOXB9
uniprot id: A0A6J2MCT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

89673:TMEM19
gene id: 89673:TMEM19
uniprot id: A0A6J2NFN5
uniprot id: A0A7E6D6B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

89673:MMP23B
gene id: 89673:MMP23B
uniprot id: A0A6J2LR01
uniprot id: A0A7E6DQ06
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114499040
gene id: 89673:LOC114499040
uniprot id: A0A6J2LXU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:RANBP9
gene id: 89673:RANBP9
uniprot id: A0A6J2LH35
names: Similarity
messages: Belongs to the RANBP9/10 family.

89673:LOC114503383
gene id: 89673:LOC114503383
uniprot id: A0A7E6EH30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

89673:LOC114512268
gene id: 89673:LOC114512268
uniprot id: A0A6J2N506
names: Similarity
messages: Belongs to the NUT family.

89673:DYNLT2B
gene id: 89673:DYNLT2B
uniprot id: A0A6J2L0N1
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

89673:FAM161A
gene id: 89673:FAM161A
uniprot id: A0A6J2LXG5
uniprot id: A0A7E6DYV0
names: Similarity
messages: Belongs to the FAM161 family.

89673:PSKH1
gene id: 89673:PSKH1
uniprot id: A0A6J2KU03
uniprot id: A0A7E6CM04
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:LOC114505727
gene id: 89673:LOC114505727
uniprot id: A0A6J2MIV9
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

89673:STX6
gene id: 89673:STX6
uniprot id: A0A6J2N9W2
names: Similarity
messages: Belongs to the syntaxin family.

89673:LOC114511454
gene id: 89673:LOC114511454
uniprot id: A0A7E6CPR3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

89673:GOLT1B
gene id: 89673:GOLT1B
uniprot id: A0A6J2NE51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

89673:TMEM39B
gene id: 89673:TMEM39B
uniprot id: A0A6J2LSM7
uniprot id: A0A6J2LSQ4
uniprot id: A0A7E6DQX7
uniprot id: A0A7E6DS23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM39 family.
messages: Membrane

89673:TIPIN
gene id: 89673:TIPIN
uniprot id: A0A6J2LCH0
uniprot id: A0A7E6CGJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSM3 family.
messages: Nucleus
messages: Plays an important role in the control of DNA replication and the maintenance of replication fork stability.

89673:TINAG
gene id: 89673:TINAG
uniprot id: A0A6J2LH02
uniprot id: A0A7E6DMD2
names: Similarity
messages: Belongs to the peptidase C1 family.

89673:LOC114510271
gene id: 89673:LOC114510271
uniprot id: A0A6J2MX27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114489472
gene id: 89673:LOC114489472
uniprot id: A0A6J2KYV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

89673:PFDN6
gene id: 89673:PFDN6
uniprot id: A0A6J2LHB9
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

89673:CHMP6
gene id: 89673:CHMP6
uniprot id: A0A6J2MF12
names: Similarity
messages: Belongs to the SNF7 family.

89673:EIF4A1
gene id: 89673:EIF4A1
uniprot id: A0A6J2NDW0
uniprot id: A0A6J2NJ48
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

89673:SSR2
gene id: 89673:SSR2
uniprot id: A0A6J2KU73
uniprot id: A0A6J2L070
uniprot id: A0A7E6CY82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-beta family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

89673:LOC114496718
gene id: 89673:LOC114496718
uniprot id: A0A6J2LQU3
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

89673:ARL6
gene id: 89673:ARL6
uniprot id: A0A6J2L556
uniprot id: A0A7E6D3K3
uniprot id: A0A7E6D3R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: cilium membrane

89673:GABARAPL2
gene id: 89673:GABARAPL2
uniprot id: A0A6J2KR45
names: Similarity
messages: Belongs to the ATG8 family.

89673:LOC114500435
gene id: 89673:LOC114500435
uniprot id: A0A7E6E405
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114504293
gene id: 89673:LOC114504293
uniprot id: A0A7E6EG17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Early endosome
messages: Endosome
messages: Involved in trafficking and recycling of synaptic vesicles.
messages: Late endosome
messages: Membrane
messages: Recycling endosome
messages: autophagosome
messages: synaptic vesicle
messages: trans-Golgi network

89673:LOXL1
gene id: 89673:LOXL1
uniprot id: A0A6J2L774
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

89673:HACD4
gene id: 89673:HACD4
uniprot id: A0A6J2ME19
uniprot id: A0A7E6DEJ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:HOXD3
gene id: 89673:HOXD3
uniprot id: A0A6J2LIA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

89673:KCNG3
gene id: 89673:KCNG3
uniprot id: A0A6J2LZG6
uniprot id: A0A6J2M0Q6
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114496116
gene id: 89673:LOC114496116
uniprot id: A0A6J2LJU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AMY1 family.
messages: Nucleus

89673:ACTR6
gene id: 89673:ACTR6
uniprot id: A0A6J2N9L2
uniprot id: A0A7E6D811
names: Similarity
messages: Belongs to the actin family.

89673:LOC114493937
gene id: 89673:LOC114493937
uniprot id: A0A6J2LEM9
names: Similarity
messages: Belongs to the heat shock protein 70 family.

89673:ARL4D
gene id: 89673:ARL4D
uniprot id: A0A6J2M840
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

89673:CCDC58
gene id: 89673:CCDC58
uniprot id: A0A6J2KYC8
uniprot id: A0A7E6D4C9
names: Similarity
messages: Belongs to the MIX23 family.

89673:MTMR4
gene id: 89673:MTMR4
uniprot id: A0A6J2MBC0
uniprot id: A0A6J2ME88
uniprot id: A0A6J2MEQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm
messages: Membrane

89673:MSRB3
gene id: 89673:MSRB3
uniprot id: A0A6J2NCT4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.
messages: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.

89673:RPS3A
gene id: 89673:RPS3A
uniprot id: A0A6J2MAW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs. Binds with high affinity to IPO4. Interacts with DDIT3.
messages: Cytoplasm
messages: May play a role during erythropoiesis through regulation of transcription factor DDIT3.
messages: Nucleus
messages: nucleolus

89673:PHOSPHO1
gene id: 89673:PHOSPHO1
uniprot id: A0A6J2MDA2
uniprot id: A0A6J2MDV7
uniprot id: A0A7E6EDN1
uniprot id: A0A7E6EE89
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.

89673:TAGLN2
gene id: 89673:TAGLN2
uniprot id: A0A6J2N811
names: Similarity
messages: Belongs to the calponin family.

89673:LOC114489395
gene id: 89673:LOC114489395
uniprot id: A0A6J2L0N2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:LOC114499059
gene id: 89673:LOC114499059
uniprot id: A0A6J2LU01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114489200
gene id: 89673:LOC114489200
uniprot id: A0A7E6CWT5
names: Similarity
messages: Belongs to the SNF7 family.

89673:TMEM116
gene id: 89673:TMEM116
uniprot id: A0A6J2MWJ8
names: Subcellular Location Annotation
messages: Membrane

89673:EIF3F
gene id: 89673:EIF3F
uniprot id: A0A6J2LVA9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit F family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm
messages: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.

89673:UTP14A
gene id: 89673:UTP14A
uniprot id: A0A6J2MJD6
uniprot id: A0A7E6D121
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP14 family.
messages: nucleolus

89673:TBXAS1
gene id: 89673:TBXAS1
uniprot id: A0A6J2MMY6
uniprot id: A0A7E6CIS8
names: Similarity
messages: Belongs to the cytochrome P450 family.

89673:LOC114497283
gene id: 89673:LOC114497283
uniprot id: A0A6J2LS88
uniprot id: A0A6J2LS95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

89673:KCNJ4
gene id: 89673:KCNJ4
uniprot id: A0A6J2N9I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

89673:NDUFA2
gene id: 89673:NDUFA2
uniprot id: A0A6J2MUI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA2 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

89673:LOC114489404
gene id: 89673:LOC114489404
uniprot id: A0A6J2KUU4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:TMSB15B
gene id: 89673:TMSB15B
uniprot id: A0A7E6CZB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

89673:ELOVL3
gene id: 89673:ELOVL3
uniprot id: A0A6J2LNH2
uniprot id: A0A7E6DW22
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:CDK2
gene id: 89673:CDK2
uniprot id: A0A6J2N8F8
uniprot id: A0A6J2NCZ6
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:LOC114515185
gene id: 89673:LOC114515185
uniprot id: A0A6J2NCS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: myofibril

89673:CKS1B
gene id: 89673:CKS1B
uniprot id: A0A6J2KYW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
messages: Forms a homohexamer that can probably bind six kinase subunits.

89673:AGPAT5
gene id: 89673:AGPAT5
uniprot id: A0A6J2MSP5
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

89673:MOCS2
gene id: 89673:MOCS2
uniprot id: A0A6J2MYJ9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MoaE family. MOCS2B subfamily.
messages: Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
messages: Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.
messages: This protein is produced by a bicistronic gene which also produces the small subunit (MOCS2A) from an overlapping reading frame.
messages: cytosol

89673:RDX
gene id: 89673:RDX
uniprot id: A0A7E6E0E5
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton
messages: microvillus

89673:ECHDC2
gene id: 89673:ECHDC2
uniprot id: A0A6J2LS05
uniprot id: A0A7E6DS22
uniprot id: A0A7E6DSR9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

89673:LOC114515184
gene id: 89673:LOC114515184
uniprot id: A0A6J2NJM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: myofibril

89673:SLC2A6
gene id: 89673:SLC2A6
uniprot id: A0A6J2MJV6
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

89673:LOC114490322
gene id: 89673:LOC114490322
uniprot id: A0A6J2KZN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114511214
gene id: 89673:LOC114511214
uniprot id: A0A6J2N665
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
messages: Component of a complex at least composed of URM1, CTU2/NCS2 and CTU1/ATPBD3. May form a heterodimer with CTU2/NCS2.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

89673:TMPRSS11A
gene id: 89673:TMPRSS11A
uniprot id: A0A7E6DDV5
uniprot id: A0A7E6DDW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Membrane

89673:SLC52A2
gene id: 89673:SLC52A2
uniprot id: A0A6J2NAP4
uniprot id: A0A7E6E7G1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

89673:TRMT5
gene id: 89673:TRMT5
uniprot id: A0A6J2L8A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM5 / TYW2 family.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Mitochondrion matrix
messages: Monomer.
messages: Nucleus
messages: Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.

89673:GTF2H3
gene id: 89673:GTF2H3
uniprot id: A0A6J2MUV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB4 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
messages: Nucleus
messages: Part of a TFIID-containing RNA polymerase II pre-initiation complex that is composed of TBP and at least GTF2A1, GTF2A2, GTF2E1, GTF2E2, GTF2F1, GTF2H2, GTF2H3, GTF2H4, GTF2H5, GTF2B, TCEA1, ERCC2, ERCC3, TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. Component of the 7-subunit TFIIH core complex composed of XPB/ERCC3, XPD/ERCC2, GTF2H1, GTF2H2, GTF2H3, GTF2H4 and GTF2H5, which is active in NER. The core complex associates with the 3-subunit CDK-activating kinase (CAK) module composed of CCNH/cyclin H, CDK7 and MNAT1 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription. Interacts with RARA; the interaction requires prior phosphorylation of RARA on 'Ser-369' which then enhances interaction of RARA with CDK7.

89673:LOC114500945
gene id: 89673:LOC114500945
uniprot id: A0A6J2M5X4
uniprot id: A0A7E6E1Z5
uniprot id: A0A7E6E247
uniprot id: A0A7E6E2V9
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

89673:NUBPL
gene id: 89673:NUBPL
uniprot id: A0A6J2L7A9
uniprot id: A0A7E6E1W0
names: Similarity
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.

89673:HBP1
gene id: 89673:HBP1
uniprot id: A0A6J2MLS6
uniprot id: A0A6J2MNK7
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

89673:PCMT1
gene id: 89673:PCMT1
uniprot id: A0A6J2LCC4
uniprot id: A0A6J2LF58
uniprot id: A0A6J2LG82
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

89673:NKIRAS1
gene id: 89673:NKIRAS1
uniprot id: A0A7E6E8Y3
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

89673:UBLCP1
gene id: 89673:UBLCP1
uniprot id: A0A6J2MVC3
uniprot id: A0A7E6CSS1
names: Subcellular Location Annotation
messages: Nucleus

89673:CIT
gene id: 89673:CIT
uniprot id: A0A6J2MTN3
uniprot id: A0A6J2MTP0
uniprot id: A0A6J2MYN5
uniprot id: A0A6J2MYP3
uniprot id: A0A7E6CTW5
uniprot id: A0A7E6CTX0
uniprot id: A0A7E6CTX1
uniprot id: A0A7E6CTX6
uniprot id: A0A7E6CTY5
uniprot id: A0A7E6CUE9
uniprot id: A0A7E6CUG2
uniprot id: A0A7E6CUM5
uniprot id: A0A7E6CUN0
uniprot id: A0A7E6CWQ0
uniprot id: A0A7E6CWQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cytoplasm
messages: Plays a role in cytokinesis. Displays serine/threonine protein kinase activity.

89673:PTPRA
gene id: 89673:PTPRA
uniprot id: A0A6J2MHI3
uniprot id: A0A7E6CEU7
uniprot id: A0A7E6CFI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 4 subfamily.
messages: Cell membrane
messages: Membrane

89673:CASKIN2
gene id: 89673:CASKIN2
uniprot id: A0A6J2MDZ9
uniprot id: A0A7E6EEJ8
uniprot id: A0A7E6EGB4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

89673:EID1
gene id: 89673:EID1
uniprot id: A0A6J2L8R9
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114492220
gene id: 89673:LOC114492220
uniprot id: A0A7E6EDA7
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Component of the large ribosomal subunit.

89673:WASF1
gene id: 89673:WASF1
uniprot id: A0A6J2LDM3
uniprot id: A0A6J2LJ90
uniprot id: A0A7E6DN99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

89673:ADCY7
gene id: 89673:ADCY7
uniprot id: A0A6J2KR03
uniprot id: A0A6J2KWK7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

89673:SDHA
gene id: 89673:SDHA
uniprot id: A0A6J2LMF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

89673:ETV2
gene id: 89673:ETV2
uniprot id: A0A7E6CR51
uniprot id: A0A7E6CR72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

89673:TMC2
gene id: 89673:TMC2
uniprot id: A0A6J2MMI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

89673:NACC2
gene id: 89673:NACC2
uniprot id: A0A6J2LUR0
names: Subcellular Location Annotation
messages: Nucleus

89673:EXOSC1
gene id: 89673:EXOSC1
uniprot id: A0A6J2LQI2
names: Subcellular Location Annotation
messages: Cytoplasm

89673:PTCD3
gene id: 89673:PTCD3
uniprot id: A0A6J2M470
uniprot id: A0A7E6DY53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS39 family.
messages: Mitochondrion

89673:LOC114512110
gene id: 89673:LOC114512110
uniprot id: A0A7E6CXM6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:CHST4
gene id: 89673:CHST4
uniprot id: A0A6J2KT02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

89673:PRICKLE1
gene id: 89673:PRICKLE1
uniprot id: A0A6J2N4Y4
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

89673:SLC25A23
gene id: 89673:SLC25A23
uniprot id: A0A6J2M7G1
uniprot id: A0A6J2MCS6
uniprot id: A0A7E6E951
uniprot id: A0A7E6E9X2
uniprot id: A0A7E6EA64
uniprot id: A0A7E6EAR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

89673:LLGL2
gene id: 89673:LLGL2
uniprot id: A0A6J2MHV9
uniprot id: A0A7E6EEK5
uniprot id: A0A7E6EF39
uniprot id: A0A7E6EF43
uniprot id: A0A7E6EFD4
uniprot id: A0A7E6EFE4
uniprot id: A0A7E6EG64
uniprot id: A0A7E6EGB8
names: Similarity
messages: Belongs to the WD repeat L(2)GL family.

89673:ITGA7
gene id: 89673:ITGA7
uniprot id: A0A6J2NA42
uniprot id: A0A6J2NFV4
uniprot id: A0A7E6D656
uniprot id: A0A7E6D6V9
uniprot id: A0A7E6D922
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:LOC118498581
gene id: 89673:LOC118498581
uniprot id: A0A7E6D168
names: Similarity
messages: Belongs to the apolipoprotein L family.

89673:LOC114513077
gene id: 89673:LOC114513077
uniprot id: A0A7E6D5T2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

89673:NR2F6
gene id: 89673:NR2F6
uniprot id: A0A6J2MAV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

89673:LOC114495207
gene id: 89673:LOC114495207
uniprot id: A0A6J2LFM4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

89673:GALNT3
gene id: 89673:GALNT3
uniprot id: A0A6J2LHU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

89673:CORO6
gene id: 89673:CORO6
uniprot id: A0A6J2MBU8
uniprot id: A0A6J2MC16
uniprot id: A0A6J2MF95
uniprot id: A0A7E6EC77
uniprot id: A0A7E6EC81
uniprot id: A0A7E6ED04
uniprot id: A0A7E6EDT3
uniprot id: A0A7E6EE08
uniprot id: A0A7E6EE12
names: Similarity
messages: Belongs to the WD repeat coronin family.

89673:LOC114514844
gene id: 89673:LOC114514844
uniprot id: A0A6J2NIA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

89673:GLI2
gene id: 89673:GLI2
uniprot id: A0A7E6DK80
uniprot id: A0A7E6DK82
uniprot id: A0A7E6DKI6
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

89673:FGFR2
gene id: 89673:FGFR2
uniprot id: A0A6J2LMP1
uniprot id: A0A6J2LQK7
uniprot id: A0A7E6DVN0
uniprot id: A0A7E6DVN4
uniprot id: A0A7E6DVN9
uniprot id: A0A7E6DVV0
uniprot id: A0A7E6DVV8
uniprot id: A0A7E6DVV9
uniprot id: A0A7E6DW92
uniprot id: A0A7E6DW99
uniprot id: A0A7E6DWM5
uniprot id: A0A7E6DWN1
uniprot id: A0A7E6DWN3
uniprot id: A0A7E6DX34
uniprot id: A0A7E6DX39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Cell membrane
messages: Membrane

89673:CAMK2N2
gene id: 89673:CAMK2N2
uniprot id: A0A6J2L480
names: Similarity
messages: Belongs to the CAMK2N family.

89673:CHPF
gene id: 89673:CHPF
uniprot id: A0A6J2LGN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

89673:GALNT13
gene id: 89673:GALNT13
uniprot id: A0A6J2LHF6
uniprot id: A0A7E6DJV1
uniprot id: A0A7E6DK49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

89673:LMX1A
gene id: 89673:LMX1A
uniprot id: A0A6J2N4G4
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114490777
gene id: 89673:LOC114490777
uniprot id: A0A7E6CXT0
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Ribosomal protein P0 is the functional equivalent of E.coli protein L10.

89673:LOC114499021
gene id: 89673:LOC114499021
uniprot id: A0A6J2LY84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:DGLUCY
gene id: 89673:DGLUCY
uniprot id: A0A6J2L8Q3
uniprot id: A0A7E6CQ26
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

89673:CDC34
gene id: 89673:CDC34
uniprot id: A0A6J2M9W3
uniprot id: A0A6J2MC42
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

89673:LOC114499695
gene id: 89673:LOC114499695
uniprot id: A0A6J2M0Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat EIPR1 family.
messages: trans-Golgi network

89673:UNC13A
gene id: 89673:UNC13A
uniprot id: A0A6J2M8J4
names: Subcellular Location Annotation
messages: Cytoplasm

89673:C14H1orf43
gene id: 89673:C14H1orf43
uniprot id: A0A6J2KSG6
uniprot id: A0A6J2KT17
uniprot id: A0A6J2KUL8
uniprot id: A0A6J2KWB9
uniprot id: A0A6J2KYF7
names: Function
names: Subcellular Location Annotation
messages: General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages.
messages: Golgi apparatus
messages: Membrane
messages: Mitochondrion

89673:SLIT2
gene id: 89673:SLIT2
uniprot id: A0A6J2L6Z5
uniprot id: A0A6J2L8B3
uniprot id: A0A6J2LCA5
uniprot id: A0A7E6D755
uniprot id: A0A7E6D789
uniprot id: A0A7E6D7A8
uniprot id: A0A7E6D7D9
uniprot id: A0A7E6D7W2
uniprot id: A0A7E6D7W7
uniprot id: A0A7E6D7Y4
uniprot id: A0A7E6DA23
uniprot id: A0A7E6DA48
uniprot id: A0A7E6DA58
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:MED13L
gene id: 89673:MED13L
uniprot id: A0A6J2MYL1
uniprot id: A0A7E6CRY4
uniprot id: A0A7E6CSL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

89673:LOC114507401
gene id: 89673:LOC114507401
uniprot id: A0A6J2MLL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114506244
gene id: 89673:LOC114506244
uniprot id: A0A6J2MHK6
uniprot id: A0A6J2MHL0
uniprot id: A0A6J2MJC6
uniprot id: A0A6J2MJQ1
names: Similarity
messages: Belongs to the G-alpha family. G(s) subfamily.

89673:MRPL3
gene id: 89673:MRPL3
uniprot id: A0A6J2M3P5
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

89673:MANBAL
gene id: 89673:MANBAL
uniprot id: A0A6J2MKW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0239 family.
messages: Membrane

89673:PLXNB1
gene id: 89673:PLXNB1
uniprot id: A0A6J2M839
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:AMDHD2
gene id: 89673:AMDHD2
uniprot id: A0A6J2LFD2
uniprot id: A0A7E6D9B9
uniprot id: A0A7E6DA81
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.
messages: Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.

89673:LOC114513055
gene id: 89673:LOC114513055
uniprot id: A0A6J2NDB9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC118499647
gene id: 89673:LOC118499647
uniprot id: A0A7E6DEI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ENSA
gene id: 89673:ENSA
uniprot id: A0A6J2KYL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.

89673:CCT6A
gene id: 89673:CCT6A
uniprot id: A0A6J2LJA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

89673:LOC114490091
gene id: 89673:LOC114490091
uniprot id: A0A7E6DHE6
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114490797
gene id: 89673:LOC114490797
uniprot id: A0A7E6DCL9
names: Subcellular Location Annotation
messages: Nucleus

89673:MEF2D
gene id: 89673:MEF2D
uniprot id: A0A6J2KSV4
uniprot id: A0A7E6CWB3
uniprot id: A0A7E6CX16
uniprot id: A0A7E6CYW8
names: Subcellular Location Annotation
messages: Nucleus

89673:BTG1
gene id: 89673:BTG1
uniprot id: A0A6J2N7C4
names: Similarity
messages: Belongs to the BTG family.

89673:TCTN3
gene id: 89673:TCTN3
uniprot id: A0A6J2LMZ9
uniprot id: A0A7E6DUV7
uniprot id: A0A7E6DW31
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

89673:TMEM50B
gene id: 89673:TMEM50B
uniprot id: A0A6J2KX15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

89673:LEAP2
gene id: 89673:LEAP2
uniprot id: A0A6J2N3P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEAP2 family.
messages: Has an antimicrobial activity.
messages: Secreted

89673:CDC42SE1
gene id: 89673:CDC42SE1
uniprot id: A0A7E6CWC8
uniprot id: A0A7E6CZ13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Interacts with CDC42 (in GTP-bound form). Interacts weakly with RAC1 and not at all with RHOA.
messages: Membrane
messages: Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages.
messages: cytoskeleton

89673:LOC114495658
gene id: 89673:LOC114495658
uniprot id: A0A6J2LL95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

89673:DHH
gene id: 89673:DHH
uniprot id: A0A6J2N9S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

89673:LOC114498000
gene id: 89673:LOC114498000
uniprot id: A0A6J2LR50
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:DHCR7
gene id: 89673:DHCR7
uniprot id: A0A6J2KWU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

89673:KRT2
gene id: 89673:KRT2
uniprot id: A0A6J2NDH8
names: Similarity
messages: Belongs to the intermediate filament family.

89673:LOC114512914
gene id: 89673:LOC114512914
uniprot id: A0A6J2N7G3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

89673:SMOC2
gene id: 89673:SMOC2
uniprot id: A0A7E6DNY4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114500163
gene id: 89673:LOC114500163
uniprot id: A0A6J2LZ05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ACAD9
gene id: 89673:ACAD9
uniprot id: A0A6J2L4X4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

89673:LOC114488893
gene id: 89673:LOC114488893
uniprot id: A0A6J2KTA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:RFTN2
gene id: 89673:RFTN2
uniprot id: A0A6J2LD18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the raftlin family.
messages: Cell membrane
messages: Membrane

89673:PPP1R9A
gene id: 89673:PPP1R9A
uniprot id: A0A7E6CHP3
uniprot id: A0A7E6CHP7
uniprot id: A0A7E6CHS6
uniprot id: A0A7E6CHZ1
uniprot id: A0A7E6CHZ6
uniprot id: A0A7E6CI41
uniprot id: A0A7E6CJR5
uniprot id: A0A7E6CJS1
names: Subcellular Location Annotation
messages: cytoskeleton

89673:LOC114496355
gene id: 89673:LOC114496355
uniprot id: A0A6J2LNU8
uniprot id: A0A7E6DRQ4
uniprot id: A0A7E6DRS5
uniprot id: A0A7E6DSD9
uniprot id: A0A7E6DSW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NASP family.
messages: Nucleus

89673:NEK6
gene id: 89673:NEK6
uniprot id: A0A6J2M4E1
uniprot id: A0A7E6DGB0
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:LOC114513221
gene id: 89673:LOC114513221
uniprot id: A0A6J2NE41
names: Similarity
messages: Belongs to the intermediate filament family.

89673:BCL2
gene id: 89673:BCL2
uniprot id: A0A6J2MSC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: Nucleus membrane

89673:TNFSF14
gene id: 89673:TNFSF14
uniprot id: A0A6J2MI84
names: Similarity
messages: Belongs to the tumor necrosis factor family.

89673:RECQL
gene id: 89673:RECQL
uniprot id: A0A6J2N6Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecQ subfamily.
messages: Nucleus

89673:SAP18
gene id: 89673:SAP18
uniprot id: A0A6J2NDK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAP18 family.
messages: Component of the SIN3-repressing complex. Enhances the ability of SIN3-HDAC1-mediated transcriptional repression. When tethered to the promoter, it can direct the formation of a repressive complex to core histone proteins. Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Component of the ASAP and PSAP complexes which bind RNA in a sequence-independent manner and are proposed to be recruited to the EJC prior to or during the splicing process and to regulate specific excision of introns in specific transcription subsets. The ASAP complex can inhibit mRNA processing during in vitro splicing reactions. The ASAP complex promotes apoptosis and is disassembled after induction of apoptosis. Involved in the splicing modulation of BCL2L1/Bcl-X (and probably other apoptotic genes); specifically inhibits the formation of proapoptotic isoforms such as Bcl-X(S); the activity is different from the established EJC assembly and function.
messages: Cytoplasm
messages: Nucleus speckle

89673:THNSL1
gene id: 89673:THNSL1
uniprot id: A0A6J2L5T0
names: Similarity
messages: Belongs to the threonine synthase family.

89673:GSG1
gene id: 89673:GSG1
uniprot id: A0A6J2NFH4
uniprot id: A0A7E6DAC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

89673:ADD1
gene id: 89673:ADD1
uniprot id: A0A6J2KW27
uniprot id: A0A6J2KW32
uniprot id: A0A6J2KWM8
uniprot id: A0A6J2KYB0
uniprot id: A0A6J2KYB5
uniprot id: A0A6J2KZX7
uniprot id: A0A6J2KZY1
uniprot id: A0A6J2L1Z3
uniprot id: A0A7E6D4A1
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

89673:AKAP3
gene id: 89673:AKAP3
uniprot id: A0A6J2NE62
names: Similarity
messages: Belongs to the AKAP110 family.

89673:LHFPL3
gene id: 89673:LHFPL3
uniprot id: A0A6J2MNS7
uniprot id: A0A6J2MTD1
names: Subcellular Location Annotation
messages: Membrane

89673:ATXN3
gene id: 89673:ATXN3
uniprot id: A0A6J2L3I8
uniprot id: A0A6J2L843
uniprot id: A0A7E6CQD3
uniprot id: A0A7E6CQH8
uniprot id: A0A7E6CQU0
uniprot id: A0A7E6CSY2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

89673:MAN1C1
gene id: 89673:MAN1C1
uniprot id: A0A6J2LVE4
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

89673:TNRC6B
gene id: 89673:TNRC6B
uniprot id: A0A7E6D8F9
uniprot id: A0A7E6D8I4
uniprot id: A0A7E6D974
names: Similarity
messages: Belongs to the GW182 family.

89673:ARSA
gene id: 89673:ARSA
uniprot id: A0A6J2NDU4
names: Similarity
messages: Belongs to the sulfatase family.

89673:CPSF3
gene id: 89673:CPSF3
uniprot id: A0A6J2LVD0
names: Subcellular Location Annotation
messages: Nucleus

89673:GRIA3
gene id: 89673:GRIA3
uniprot id: A0A6J2MGY9
uniprot id: A0A6J2MK81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

89673:TMED5
gene id: 89673:TMED5
uniprot id: A0A6J2LK03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

89673:NOTCH3
gene id: 89673:NOTCH3
uniprot id: A0A6J2M716
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

89673:POLE2
gene id: 89673:POLE2
uniprot id: A0A6J2L509
uniprot id: A0A6J2L8M3
uniprot id: A0A7E6DZY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase epsilon subunit B family.
messages: Nucleus
messages: Participates in DNA repair and in chromosomal DNA replication.

89673:PTH2
gene id: 89673:PTH2
uniprot id: A0A6J2N5A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: Secreted

89673:SPPL2B
gene id: 89673:SPPL2B
uniprot id: A0A6J2MBH0
uniprot id: A0A6J2MEN5
uniprot id: A0A7E6E8U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Endosome membrane
messages: Lysosome membrane
messages: Membrane

89673:LOC114514434
gene id: 89673:LOC114514434
uniprot id: A0A7E6E7R8
names: Similarity
messages: Belongs to the gasdermin family.

89673:LOC114504888
gene id: 89673:LOC114504888
uniprot id: A0A7E6D211
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Cytoplasm

89673:TGIF2LX
gene id: 89673:TGIF2LX
uniprot id: A0A6J2MK51
names: Subcellular Location Annotation
messages: Nucleus

89673:PPP6R3
gene id: 89673:PPP6R3
uniprot id: A0A6J2LYT9
uniprot id: A0A7E6E2B7
uniprot id: A0A7E6E2C3
uniprot id: A0A7E6E2C7
uniprot id: A0A7E6E2V6
uniprot id: A0A7E6E2V7
uniprot id: A0A7E6E2W2
uniprot id: A0A7E6E339
uniprot id: A0A7E6E344
uniprot id: A0A7E6E346
uniprot id: A0A7E6E3S4
uniprot id: A0A7E6E3S5
uniprot id: A0A7E6E3S9
uniprot id: A0A7E6E3T2
uniprot id: A0A7E6E3T4
uniprot id: A0A7E6E3T7
names: Similarity
messages: Belongs to the SAPS family.

89673:ROM1
gene id: 89673:ROM1
uniprot id: A0A6J2LYF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRPH2/ROM1 family.
messages: Membrane

89673:TRPM3
gene id: 89673:TRPM3
uniprot id: A0A7E6DF47
names: Subcellular Location Annotation
messages: Membrane

89673:FLNC
gene id: 89673:FLNC
uniprot id: A0A6J2MSQ6
names: Similarity
messages: Belongs to the filamin family.

89673:ADGRG7
gene id: 89673:ADGRG7
uniprot id: A0A7E6D3U1
names: Subcellular Location Annotation
messages: Membrane

89673:TECR
gene id: 89673:TECR
uniprot id: A0A6J2M841
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:ACTL6B
gene id: 89673:ACTL6B
uniprot id: A0A6J2M4F1
uniprot id: A0A7E6DBU9
uniprot id: A0A7E6DCI7
names: Similarity
messages: Belongs to the actin family.

89673:LOC114513843
gene id: 89673:LOC114513843
uniprot id: A0A7E6DAE1
names: Subcellular Location Annotation
messages: Membrane

89673:PMS1
gene id: 89673:PMS1
uniprot id: A0A7E6DJ31
uniprot id: A0A7E6DJ95
uniprot id: A0A7E6DJA3
uniprot id: A0A7E6DJG0
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

89673:CCT3
gene id: 89673:CCT3
uniprot id: A0A6J2KSV5
uniprot id: A0A6J2KWP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

89673:LOC114492756
gene id: 89673:LOC114492756
uniprot id: A0A7E6E284
names: Similarity
messages: Belongs to the NipSnap family.

89673:LOC114497479
gene id: 89673:LOC114497479
uniprot id: A0A7E6DVS4
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

89673:RNGTT
gene id: 89673:RNGTT
uniprot id: A0A6J2LBH5
uniprot id: A0A6J2LCI3
uniprot id: A0A7E6DMH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate.
messages: In the C-terminal section; belongs to the eukaryotic GTase family.
messages: In the N-terminal section; belongs to the non-receptor class of the protein-tyrosine phosphatase family.
messages: Nucleus

89673:LOC114489378
gene id: 89673:LOC114489378
uniprot id: A0A6J2L0L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

89673:KCNA4
gene id: 89673:KCNA4
uniprot id: A0A6J2M0L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.4/KCNA4 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: axon

89673:PHACTR1
gene id: 89673:PHACTR1
uniprot id: A0A7E6DT62
uniprot id: A0A7E6DTA9
uniprot id: A0A7E6DTR8
uniprot id: A0A7E6DTY6
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

89673:SLC11A1
gene id: 89673:SLC11A1
uniprot id: A0A6J2LJE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Macrophage-specific antiporter that fluxes metal ions in either direction against a proton gradient. Localized to late endosomal lysosomal membranes, delivers bivalent cations from the cytosol into these acidic compartments where they may directly affect antimicrobial activity. Involved in iron metabolism and host natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis of its protective enzymes.

89673:AP2B1
gene id: 89673:AP2B1
uniprot id: A0A6J2MC57
uniprot id: A0A6J2MCR6
uniprot id: A0A7E6EF60
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

89673:GPR137C
gene id: 89673:GPR137C
uniprot id: A0A6J2L4N7
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

89673:IP6K3
gene id: 89673:IP6K3
uniprot id: A0A6J2LG06
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

89673:SPNS2
gene id: 89673:SPNS2
uniprot id: A0A6J2NJW1
uniprot id: A0A7E6ECT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

89673:C6H11orf1
gene id: 89673:C6H11orf1
uniprot id: A0A6J2LYA9
uniprot id: A0A6J2LZE0
uniprot id: A0A7E6DZ54
uniprot id: A0A7E6E023
names: Function
names: Subcellular Location Annotation
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.
messages: cilium axoneme

89673:ZNF483
gene id: 89673:ZNF483
uniprot id: A0A6J2L9C8
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114501915
gene id: 89673:LOC114501915
uniprot id: A0A6J2LFE8
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: Involved in oxygen transport from the lung to the various peripheral tissues.

89673:HTR6
gene id: 89673:HTR6
uniprot id: A0A6J2LVL5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:LOC114501567
gene id: 89673:LOC114501567
uniprot id: A0A6J2M383
names: Similarity
messages: Belongs to the peptidase C14A family.

89673:TNC
gene id: 89673:TNC
uniprot id: A0A6J2LQ01
uniprot id: A0A7E6DG47
uniprot id: A0A7E6DG59
uniprot id: A0A7E6DG66
uniprot id: A0A7E6DGB6
uniprot id: A0A7E6DGB8
uniprot id: A0A7E6DGC4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

89673:LOC114499895
gene id: 89673:LOC114499895
uniprot id: A0A7E6DZ96
names: Similarity
messages: Belongs to the peptidase C14A family.

89673:CDR2L
gene id: 89673:CDR2L
uniprot id: A0A6J2MH33
names: Similarity
messages: Belongs to the CDR2 family.

89673:APOA5
gene id: 89673:APOA5
uniprot id: A0A6J2M2Q9
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

89673:LOC114504315
gene id: 89673:LOC114504315
uniprot id: A0A6J2MCT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CWC25
gene id: 89673:CWC25
uniprot id: A0A6J2MFM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CWC25 family.
messages: Nucleus

89673:HCK
gene id: 89673:HCK
uniprot id: A0A6J2MME7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

89673:ADAM8
gene id: 89673:ADAM8
uniprot id: A0A6J2LPL8
uniprot id: A0A7E6DWU0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:VIL1
gene id: 89673:VIL1
uniprot id: A0A6J2LIP6
names: Similarity
messages: Belongs to the villin/gelsolin family.

89673:PPP1R14B
gene id: 89673:PPP1R14B
uniprot id: A0A6J2LW41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP1 inhibitor family.
messages: Cytoplasm
messages: Inhibitor of PPP1CA.

89673:CNOT1
gene id: 89673:CNOT1
uniprot id: A0A6J2KR63
uniprot id: A0A6J2KR68
uniprot id: A0A6J2KRT1
uniprot id: A0A6J2KRT6
uniprot id: A0A6J2KTF5
uniprot id: A0A6J2KXC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT1 family.
messages: Nucleus

89673:LOC118499685
gene id: 89673:LOC118499685
uniprot id: A0A7E6DEX5
names: Subcellular Location Annotation
messages: Secreted

89673:RACK1
gene id: 89673:RACK1
uniprot id: A0A6J2MVY0
names: Similarity
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.

89673:STRA6
gene id: 89673:STRA6
uniprot id: A0A6J2LCB4
uniprot id: A0A7E6DYS8
uniprot id: A0A7E6DYT2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:SMPD1
gene id: 89673:SMPD1
uniprot id: A0A6J2LYT1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Converts sphingomyelin to ceramide.
messages: Secreted

89673:LOC114490351
gene id: 89673:LOC114490351
uniprot id: A0A6J2L1G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CSNK1A1
gene id: 89673:CSNK1A1
uniprot id: A0A6J2MUD2
uniprot id: A0A6J2MVZ0
uniprot id: A0A6J2MVZ5
uniprot id: A0A6J2MW08
uniprot id: A0A6J2MW12
uniprot id: A0A6J2N0K6
uniprot id: A0A6J2N0L1
uniprot id: A0A6J2N169
uniprot id: A0A7E6CS82
uniprot id: A0A7E6CSX4
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:PARD6B
gene id: 89673:PARD6B
uniprot id: A0A6J2MLQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

89673:KXD1
gene id: 89673:KXD1
uniprot id: A0A6J2M7X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KXD1 family.
messages: Lysosome membrane

89673:NPRL2
gene id: 89673:NPRL2
uniprot id: A0A6J2M121
names: Similarity
messages: Belongs to the NPR2 family.

89673:LOC114490703
gene id: 89673:LOC114490703
uniprot id: A0A7E6DF10
uniprot id: A0A7E6DF21
names: Subcellular Location Annotation
messages: Nucleus

89673:TMEM41B
gene id: 89673:TMEM41B
uniprot id: A0A6J2M1D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM41 family.
messages: Membrane

89673:PREB
gene id: 89673:PREB
uniprot id: A0A6J2M258
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat SEC12 family.
messages: Endoplasmic reticulum membrane
messages: Guanine nucleotide exchange factor that specifically activates the small GTPase SAR1B. Mediates the recruitment of SAR1B and other COPII coat components to endoplasmic reticulum membranes and is therefore required for the formation of COPII transport vesicles from the ER.
messages: Interacts with SAR1B (GDP-bound form). Interacts with MIA2; recruits PREB to endoplasmic reticulum exit sites.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Was first identified based on its probable role in the regulation of pituitary gene transcription. Binds to the prolactin gene (PRL) promoter and seems to activate transcription.

89673:TSPAN9
gene id: 89673:TSPAN9
uniprot id: A0A6J2NAD9
uniprot id: A0A6J2NG60
uniprot id: A0A7E6D834
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

89673:DTX3
gene id: 89673:DTX3
uniprot id: A0A6J2N5R0
uniprot id: A0A6J2N7I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

89673:RPL35A
gene id: 89673:RPL35A
uniprot id: A0A6J2L207
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

89673:LOC114500712
gene id: 89673:LOC114500712
uniprot id: A0A6J2M1X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CRELD1
gene id: 89673:CRELD1
uniprot id: A0A6J2M1F2
uniprot id: A0A6J2M720
uniprot id: A0A7E6E6U0
names: Caution
names: Similarity
messages: Belongs to the CRELD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:TSHZ1
gene id: 89673:TSHZ1
uniprot id: A0A7E6CGV5
names: Similarity
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.

89673:TFEB
gene id: 89673:TFEB
uniprot id: A0A6J2LHU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

89673:TFRC
gene id: 89673:TFRC
uniprot id: A0A6J2L3J2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Acts as a lipid sensor that regulates mitochondrial fusion by regulating activation of the JNK pathway.
messages: Homodimer; disulfide-linked.
messages: Melanosome
messages: Membrane
messages: Stearoylated.

89673:PTGIR
gene id: 89673:PTGIR
uniprot id: A0A6J2N758
uniprot id: A0A7E6CN25
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:CLCA1
gene id: 89673:CLCA1
uniprot id: A0A6J2LGN2
names: Similarity
messages: Belongs to the CLCR family.

89673:PSMG2
gene id: 89673:PSMG2
uniprot id: A0A6J2MKW3
uniprot id: A0A7E6CE10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PSMG2 family.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1.
messages: Forms a heterodimer with PSMG1.

89673:TFDP1
gene id: 89673:TFDP1
uniprot id: A0A7E6CKG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

89673:LOC114498978
gene id: 89673:LOC114498978
uniprot id: A0A7E6E3E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.

89673:RPL12
gene id: 89673:RPL12
uniprot id: A0A6J2M6M6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Binds directly to 26S ribosomal RNA.

89673:EPS8L2
gene id: 89673:EPS8L2
uniprot id: A0A6J2LZ06
uniprot id: A0A7E6E2J2
names: Similarity
messages: Belongs to the EPS8 family.

89673:GALR1
gene id: 89673:GALR1
uniprot id: A0A6J2MSC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

89673:LOC114505644
gene id: 89673:LOC114505644
uniprot id: A0A7E6D1E1
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

89673:KCNAB3
gene id: 89673:KCNAB3
uniprot id: A0A6J2NJD0
uniprot id: A0A7E6EC69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cytoplasm

89673:FAM189A1
gene id: 89673:FAM189A1
uniprot id: A0A7E6CPE8
names: Similarity
messages: Belongs to the ENTREP family.

89673:IL1F10
gene id: 89673:IL1F10
uniprot id: A0A6J2LT77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens.
messages: Belongs to the IL-1 family.
messages: Secreted

89673:NEU3
gene id: 89673:NEU3
uniprot id: A0A6J2LVV8
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

89673:NXN
gene id: 89673:NXN
uniprot id: A0A6J2MCA7
names: Similarity
messages: Belongs to the nucleoredoxin family.

89673:RPA3
gene id: 89673:RPA3
uniprot id: A0A6J2MUJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 3 family.
messages: Nucleus

89673:CCDC43
gene id: 89673:CCDC43
uniprot id: A0A6J2M8G4
uniprot id: A0A7E6EE90
names: Similarity
messages: Belongs to the CCDC43 family.

89673:KIF9
gene id: 89673:KIF9
uniprot id: A0A6J2M3S8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

89673:PIH1D2
gene id: 89673:PIH1D2
uniprot id: A0A6J2LS94
uniprot id: A0A6J2LT45
uniprot id: A0A7E6DZ45
uniprot id: A0A7E6E011
names: Similarity
messages: Belongs to the PIH1 family.

89673:UBALD2
gene id: 89673:UBALD2
uniprot id: A0A6J2MCM0
names: Similarity
messages: Belongs to the UBALD family.

89673:NOG
gene id: 89673:NOG
uniprot id: A0A6J2M938
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the noggin family.
messages: Homodimer.
messages: Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.
messages: Secreted

89673:LOC114499068
gene id: 89673:LOC114499068
uniprot id: A0A6J2LXX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114489568
gene id: 89673:LOC114489568
uniprot id: A0A6J2KXD7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with UHRF2/NIRF.
messages: May be involved in cell cycle regulation.
messages: Nucleus

89673:LOC118499397
gene id: 89673:LOC118499397
uniprot id: A0A7E6D9M1
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

89673:PSMD3
gene id: 89673:PSMD3
uniprot id: A0A6J2MEB4
names: Similarity
messages: Belongs to the proteasome subunit S3 family.

89673:DPM1
gene id: 89673:DPM1
uniprot id: A0A6J2MKC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum
messages: Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins; catalytic subunit of the dolichol-phosphate mannose (DPM) synthase complex.

89673:LOC114492624
gene id: 89673:LOC114492624
uniprot id: A0A6J2L5X3
uniprot id: A0A7E6E8M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro.
messages: Belongs to the 7B2 family.
messages: Interacts with PCSK2/PC2 early in the secretory pathway. Dissociation occurs at later stages.
messages: Secreted

89673:IFNE
gene id: 89673:IFNE
uniprot id: A0A6J2L7A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

89673:PKIG
gene id: 89673:PKIG
uniprot id: A0A6J2MJY6
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

89673:LOC114492349
gene id: 89673:LOC114492349
uniprot id: A0A6J2L671
uniprot id: A0A7E6D9W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

89673:GORASP1
gene id: 89673:GORASP1
uniprot id: A0A6J2M864
uniprot id: A0A7E6E4U7
names: Similarity
messages: Belongs to the GORASP family.

89673:STRN4
gene id: 89673:STRN4
uniprot id: A0A6J2N4U7
uniprot id: A0A7E6CQG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

89673:UBE2E3
gene id: 89673:UBE2E3
uniprot id: A0A6J2LFC7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

89673:PHKA2
gene id: 89673:PHKA2
uniprot id: A0A6J2MFQ5
uniprot id: A0A6J2MJ40
uniprot id: A0A7E6D0V2
uniprot id: A0A7E6D1K4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

89673:LOC114504811
gene id: 89673:LOC114504811
uniprot id: A0A7E6D2M3
names: Similarity
messages: Belongs to the TMA7 family.

89673:LOC114510426
gene id: 89673:LOC114510426
uniprot id: A0A6J2MXI6
uniprot id: A0A6J2MZ51
uniprot id: A0A6J2MZ54
uniprot id: A0A6J2MZ62
uniprot id: A0A6J2MZ68
uniprot id: A0A6J2N3Q5
uniprot id: A0A6J2N4G6
uniprot id: A0A7E6DBI3
uniprot id: A0A7E6DBP3
uniprot id: A0A7E6DC28
uniprot id: A0A7E6DCR4
names: Subcellular Location Annotation
messages: Nucleus

89673:RBM15B
gene id: 89673:RBM15B
uniprot id: A0A6J2M4F6
names: Similarity
messages: Belongs to the RRM Spen family.

89673:DBX1
gene id: 89673:DBX1
uniprot id: A0A6J2LWE2
names: Subcellular Location Annotation
messages: Nucleus

89673:CREB5
gene id: 89673:CREB5
uniprot id: A0A6J2MRA2
uniprot id: A0A6J2MW13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

89673:MYO18A
gene id: 89673:MYO18A
uniprot id: A0A7E6EC94
uniprot id: A0A7E6ECV9
uniprot id: A0A7E6ED18
uniprot id: A0A7E6EDU8
uniprot id: A0A7E6EE28
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:CDIPT
gene id: 89673:CDIPT
uniprot id: A0A6J2N1R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

89673:SLC6A20
gene id: 89673:SLC6A20
uniprot id: A0A6J2M7W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

89673:CER1
gene id: 89673:CER1
uniprot id: A0A6J2N523
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:SCFD1
gene id: 89673:SCFD1
uniprot id: A0A6J2L7Z2
uniprot id: A0A6J2L9E7
uniprot id: A0A7E6E301
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

89673:NKX2-5
gene id: 89673:NKX2-5
uniprot id: A0A6J2MY26
names: Subcellular Location Annotation
messages: Nucleus

89673:SHH
gene id: 89673:SHH
uniprot id: A0A6J2MQ69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

89673:LOC114499047
gene id: 89673:LOC114499047
uniprot id: A0A6J2LTZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114500490
gene id: 89673:LOC114500490
uniprot id: A0A6J2M4L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:IFT57
gene id: 89673:IFT57
uniprot id: A0A6J2L414
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFT57 family.
messages: cilium basal body

89673:NDUFS2
gene id: 89673:NDUFS2
uniprot id: A0A6J2KX33
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

89673:MICAL3
gene id: 89673:MICAL3
uniprot id: A0A7E6CJG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Cytoplasm

89673:CAP1
gene id: 89673:CAP1
uniprot id: A0A6J2LQM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAP family.
messages: Cell membrane
messages: Membrane

89673:LOC114507838
gene id: 89673:LOC114507838
uniprot id: A0A6J2MUL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SLC29A3
gene id: 89673:SLC29A3
uniprot id: A0A6J2LVC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

89673:ARMT1
gene id: 89673:ARMT1
uniprot id: A0A6J2LI66
uniprot id: A0A7E6DP83
names: Domain
names: Function
names: Similarity
messages: Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.
messages: Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism. Has also been shown to have O-methyltransferase activity that methylates glutamate residues of target proteins to form gamma-glutamyl methyl ester residues. Possibly methylates PCNA, suggesting it is involved in the DNA damage response.
messages: Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine.

89673:MAP1LC3C
gene id: 89673:MAP1LC3C
uniprot id: A0A6J2NAG6
uniprot id: A0A7E6CY47
names: Similarity
messages: Belongs to the ATG8 family.

89673:FOXD3
gene id: 89673:FOXD3
uniprot id: A0A6J2LRS5
names: Subcellular Location Annotation
messages: Nucleus

89673:PROX2
gene id: 89673:PROX2
uniprot id: A0A6J2L7P1
names: Subcellular Location Annotation
messages: Nucleus

89673:LYVE1
gene id: 89673:LYVE1
uniprot id: A0A6J2LWH0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:RTRAF
gene id: 89673:RTRAF
uniprot id: A0A6J2L2F0
names: Similarity
messages: Belongs to the RTRAF family.

89673:PTPN22
gene id: 89673:PTPN22
uniprot id: A0A7E6CWN5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 4 subfamily.

89673:LOC114503776
gene id: 89673:LOC114503776
uniprot id: A0A6J2MD41
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

89673:MRPS33
gene id: 89673:MRPS33
uniprot id: A0A6J2MUE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS33 family.
messages: Mitochondrion

89673:TNK1
gene id: 89673:TNK1
uniprot id: A0A6J2NE04
uniprot id: A0A6J2NJH1
uniprot id: A0A7E6ECA6
uniprot id: A0A7E6ED62
names: Subcellular Location Annotation
messages: Cell membrane

89673:ATP6V1B2
gene id: 89673:ATP6V1B2
uniprot id: A0A6J2M8T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.

89673:SGSM3
gene id: 89673:SGSM3
uniprot id: A0A6J2N8F7
uniprot id: A0A6J2NF82
uniprot id: A0A7E6D8E0
uniprot id: A0A7E6D8G7
uniprot id: A0A7E6D8J4
names: Similarity
messages: Belongs to the small G protein signaling modulator family.

89673:LOC114490295
gene id: 89673:LOC114490295
uniprot id: A0A6J2KZL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

89673:RIN1
gene id: 89673:RIN1
uniprot id: A0A6J2M2I0
uniprot id: A0A7E6E2N9
names: Similarity
messages: Belongs to the RIN (Ras interaction/interference) family.

89673:PDE1C
gene id: 89673:PDE1C
uniprot id: A0A6J2MR62
uniprot id: A0A6J2MVV9
uniprot id: A0A7E6CHB5
uniprot id: A0A7E6CHN5
uniprot id: A0A7E6CJB6
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

89673:IL19
gene id: 89673:IL19
uniprot id: A0A6J2N9F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

89673:LOC114504657
gene id: 89673:LOC114504657
uniprot id: A0A6J2MFU6
names: Similarity
messages: Belongs to the GPRASP family.

89673:BRPF3
gene id: 89673:BRPF3
uniprot id: A0A7E6DLB3
uniprot id: A0A7E6DLB8
uniprot id: A0A7E6DM19
names: Subcellular Location Annotation
messages: Nucleus

89673:DNAH6
gene id: 89673:DNAH6
uniprot id: A0A7E6DZ14
uniprot id: A0A7E6DZE7
names: Similarity
messages: Belongs to the dynein heavy chain family.

89673:GNB3
gene id: 89673:GNB3
uniprot id: A0A6J2N6D3
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

89673:PSMD4
gene id: 89673:PSMD4
uniprot id: A0A6J2KUD5
uniprot id: A0A6J2KW34
names: Similarity
messages: Belongs to the proteasome subunit S5A family.

89673:C13H12orf43
gene id: 89673:C13H12orf43
uniprot id: A0A6J2MVN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUSTOS family.
messages: Nucleus envelope

89673:ZSCAN2
gene id: 89673:ZSCAN2
uniprot id: A0A6J2KTY2
names: Subcellular Location Annotation
messages: Nucleus

89673:ASPM
gene id: 89673:ASPM
uniprot id: A0A7E6CY50
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114500847
gene id: 89673:LOC114500847
uniprot id: A0A6J2M568
names: Subcellular Location Annotation
messages: Membrane

89673:CLDND2
gene id: 89673:CLDND2
uniprot id: A0A6J2N804
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

89673:SGCB
gene id: 89673:SGCB
uniprot id: A0A6J2L9D4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
messages: Cross-link to form 2 major subcomplexes: one consisting of SGCB, SGCD and SGCG and the other consisting of SGCB and SGCD. The association between SGCB and SGCG is particularly strong while SGCA is loosely associated with the other sarcoglycans.
messages: cytoskeleton
messages: sarcolemma

89673:LOC114507695
gene id: 89673:LOC114507695
uniprot id: A0A6J2MPL9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

89673:THEMIS2
gene id: 89673:THEMIS2
uniprot id: A0A6J2LSB3
uniprot id: A0A7E6DRD3
names: Similarity
messages: Belongs to the themis family.

89673:STAC3
gene id: 89673:STAC3
uniprot id: A0A6J2N7J6
uniprot id: A0A7E6D5Z2
uniprot id: A0A7E6D8Q3
names: Subcellular Location Annotation
messages: sarcolemma

89673:NMI
gene id: 89673:NMI
uniprot id: A0A6J2LCP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NMI family.
messages: Cytoplasm
messages: Nucleus
messages: Secreted

89673:LOC114492701
gene id: 89673:LOC114492701
uniprot id: A0A6J2L7Q1
names: Similarity
messages: Belongs to the cytochrome P450 family.

89673:AKT1
gene id: 89673:AKT1
uniprot id: A0A6J2L5H7
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

89673:VLDLR
gene id: 89673:VLDLR
uniprot id: A0A6J2LRU0
uniprot id: A0A6J2LRV0
uniprot id: A0A7E6DEY0
uniprot id: A0A7E6DF14
uniprot id: A0A7E6DF26
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC118498105
gene id: 89673:LOC118498105
uniprot id: A0A7E6CVR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

89673:THRAP3
gene id: 89673:THRAP3
uniprot id: A0A6J2LJF3
uniprot id: A0A6J2LKM4
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

89673:TATDN3
gene id: 89673:TATDN3
uniprot id: A0A6J2N3Y6
uniprot id: A0A6J2N9E5
uniprot id: A0A7E6CUY9
uniprot id: A0A7E6CUZ6
uniprot id: A0A7E6CUZ9
uniprot id: A0A7E6CVG7
uniprot id: A0A7E6CVQ9
uniprot id: A0A7E6CVR4
uniprot id: A0A7E6CXS2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

89673:LIG4
gene id: 89673:LIG4
uniprot id: A0A6J2MWU8
uniprot id: A0A7E6CKB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

89673:ISOC1
gene id: 89673:ISOC1
uniprot id: A0A6J2MN77
names: Similarity
messages: Belongs to the isochorismatase family.

89673:GCH1
gene id: 89673:GCH1
uniprot id: A0A6J2LBW3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

89673:ADA2
gene id: 89673:ADA2
uniprot id: A0A6J2MXL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. ADGF subfamily.
messages: Secreted

89673:EXTL2
gene id: 89673:EXTL2
uniprot id: A0A7E6CX37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:FAS
gene id: 89673:FAS
uniprot id: A0A7E6DWK1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

89673:PLAT
gene id: 89673:PLAT
uniprot id: A0A6J2MSZ0
uniprot id: A0A6J2MXH1
uniprot id: A0A6J2MXV7
uniprot id: A0A7E6CKL1
uniprot id: A0A7E6CKL3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:PARP8
gene id: 89673:PARP8
uniprot id: A0A6J2LQD1
names: Similarity
messages: Belongs to the ARTD/PARP family.

89673:LOC114513051
gene id: 89673:LOC114513051
uniprot id: A0A6J2NDB4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ADGRG4
gene id: 89673:ADGRG4
uniprot id: A0A6J2MI77
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:LOC114503716
gene id: 89673:LOC114503716
uniprot id: A0A6J2MAR1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:DOCK11
gene id: 89673:DOCK11
uniprot id: A0A6J2MFA3
uniprot id: A0A7E6CZT6
uniprot id: A0A7E6D2F3
names: Similarity
messages: Belongs to the DOCK family.

89673:LOC114508036
gene id: 89673:LOC114508036
uniprot id: A0A7E6DCH5
uniprot id: A0A7E6DD75
names: Similarity
messages: Belongs to the mesothelin family.

89673:MEGF8
gene id: 89673:MEGF8
uniprot id: A0A7E6CP14
uniprot id: A0A7E6CP84
uniprot id: A0A7E6CPA3
uniprot id: A0A7E6CRG9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:EYA3
gene id: 89673:EYA3
uniprot id: A0A6J2LJ09
uniprot id: A0A6J2LNZ0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

89673:ALDH4A1
gene id: 89673:ALDH4A1
uniprot id: A0A6J2LP50
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

89673:LOC114498643
gene id: 89673:LOC114498643
uniprot id: A0A7E6DZY7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

89673:LOC114490749
gene id: 89673:LOC114490749
uniprot id: A0A7E6D9K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TORC family.
messages: Nucleus

89673:LOC114503092
gene id: 89673:LOC114503092
uniprot id: A0A6J2MA45
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114497089
gene id: 89673:LOC114497089
uniprot id: A0A6J2LMH6
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

89673:SLC37A3
gene id: 89673:SLC37A3
uniprot id: A0A6J2MMF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

89673:LOC114488676
gene id: 89673:LOC114488676
uniprot id: A0A7E6DFX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114500954
gene id: 89673:LOC114500954
uniprot id: A0A6J2M0F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:HEBP1
gene id: 89673:HEBP1
uniprot id: A0A6J2N771
names: Similarity
messages: Belongs to the HEBP family.

89673:YY1
gene id: 89673:YY1
uniprot id: A0A6J2L210
names: Similarity
messages: Belongs to the YY transcription factor family.

89673:LOC114504428
gene id: 89673:LOC114504428
uniprot id: A0A7E6DET9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC7 family.
messages: Nucleus
messages: Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.

89673:HDDC2
gene id: 89673:HDDC2
uniprot id: A0A6J2LE81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HDDC2 family.
messages: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
messages: Homodimer.

89673:SLC5A12
gene id: 89673:SLC5A12
uniprot id: A0A6J2LYS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

89673:BCAT1
gene id: 89673:BCAT1
uniprot id: A0A6J2N9B2
uniprot id: A0A6J2N9L9
uniprot id: A0A6J2NEW8
uniprot id: A0A7E6D7B5
uniprot id: A0A7E6D7F2
uniprot id: A0A7E6DA62
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

89673:TUSC3
gene id: 89673:TUSC3
uniprot id: A0A6J2MRQ7
uniprot id: A0A7E6CL06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:HSPA4
gene id: 89673:HSPA4
uniprot id: A0A6J2MZE2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 70 family.
messages: Cytoplasm
messages: Interacts with TJP1/ZO-1.

89673:TEX13D
gene id: 89673:TEX13D
uniprot id: A0A7E6CYX6
names: Similarity
messages: Belongs to the TEX13 family.

89673:BDH1
gene id: 89673:BDH1
uniprot id: A0A6J2KYI3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

89673:CPVL
gene id: 89673:CPVL
uniprot id: A0A6J2MQT0
names: Similarity
messages: Belongs to the peptidase S10 family.

89673:CDH22
gene id: 89673:CDH22
uniprot id: A0A6J2MLY2
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

89673:CENPU
gene id: 89673:CENPU
uniprot id: A0A7E6CJ95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-U/AME1 family.
messages: Nucleus

89673:GNPNAT1
gene id: 89673:GNPNAT1
uniprot id: A0A6J2LDG9
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. GNA1 subfamily.
messages: Homodimer.

89673:ASXL3
gene id: 89673:ASXL3
uniprot id: A0A7E6CDJ6
uniprot id: A0A7E6CDM4
uniprot id: A0A7E6CFV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Asx family.
messages: Nucleus

89673:DRD2
gene id: 89673:DRD2
uniprot id: A0A6J2LWG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Membrane

89673:LOC118497691
gene id: 89673:LOC118497691
uniprot id: A0A7E6CRT9
names: Subcellular Location Annotation
messages: Nucleus

89673:DAPK2
gene id: 89673:DAPK2
uniprot id: A0A6J2L8H4
uniprot id: A0A7E6EFN4
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:SCNN1A
gene id: 89673:SCNN1A
uniprot id: A0A6J2N7E0
uniprot id: A0A6J2NCK3
uniprot id: A0A7E6D1S4
names: Subcellular Location Annotation
messages: Membrane

89673:FAM241A
gene id: 89673:FAM241A
uniprot id: A0A6J2MBT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM241 family.
messages: Membrane

89673:LOC114498906
gene id: 89673:LOC114498906
uniprot id: A0A6J2LUL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:POLM
gene id: 89673:POLM
uniprot id: A0A6J2L126
uniprot id: A0A7E6CH10
uniprot id: A0A7E6CH80
uniprot id: A0A7E6CJ25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ).
messages: Nucleus

89673:HFE
gene id: 89673:HFE
uniprot id: A0A7E6CZK0
names: Similarity
messages: Belongs to the MHC class I family.

89673:FAM20B
gene id: 89673:FAM20B
uniprot id: A0A6J2N3P5
names: Similarity
messages: Belongs to the FAM20 family.

89673:EBAG9
gene id: 89673:EBAG9
uniprot id: A0A6J2NCD9
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.

89673:CPM
gene id: 89673:CPM
uniprot id: A0A6J2NBU1
names: Similarity
messages: Belongs to the peptidase M14 family.

89673:CBFA2T2
gene id: 89673:CBFA2T2
uniprot id: A0A6J2MLF4
uniprot id: A0A7E6CF65
names: Similarity
messages: Belongs to the CBFA2T family.

89673:RHO
gene id: 89673:RHO
uniprot id: A0A6J2M6I8
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Contains one covalently linked retinal chromophore.
messages: Membrane

89673:EPB41
gene id: 89673:EPB41
uniprot id: A0A6J2LKC4
uniprot id: A0A6J2LMX3
uniprot id: A0A7E6DQN4
uniprot id: A0A7E6DQN8
uniprot id: A0A7E6DQP3
uniprot id: A0A7E6DQP6
uniprot id: A0A7E6DQR3
uniprot id: A0A7E6DQR9
uniprot id: A0A7E6DQS4
uniprot id: A0A7E6DQS9
uniprot id: A0A7E6DRD4
uniprot id: A0A7E6DRD9
uniprot id: A0A7E6DRE1
uniprot id: A0A7E6DRE5
uniprot id: A0A7E6DRG3
uniprot id: A0A7E6DRG9
uniprot id: A0A7E6DRH3
uniprot id: A0A7E6DRH9
uniprot id: A0A7E6DRV8
uniprot id: A0A7E6DRW3
uniprot id: A0A7E6DRW7
uniprot id: A0A7E6DRX3
names: Subcellular Location Annotation
messages: Nucleus
messages: cell cortex
messages: cytoskeleton

89673:GNG14
gene id: 89673:GNG14
uniprot id: A0A6J2MH39
uniprot id: A0A7E6E9K3
uniprot id: A0A7E6EAE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

89673:NAA40
gene id: 89673:NAA40
uniprot id: A0A6J2M586
uniprot id: A0A7E6E392
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA40 subfamily.
messages: Cytoplasm
messages: Nucleus

89673:LOC114505410
gene id: 89673:LOC114505410
uniprot id: A0A6J2MIH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:GUCA2B
gene id: 89673:GUCA2B
uniprot id: A0A6J2LN97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylin family.
messages: Secreted

89673:IPO5
gene id: 89673:IPO5
uniprot id: A0A6J2MT72
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

89673:LAMC3
gene id: 89673:LAMC3
uniprot id: A0A7E6DH45
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

89673:PCSK7
gene id: 89673:PCSK7
uniprot id: A0A7E6E360
names: Similarity
messages: Belongs to the peptidase S8 family.

89673:KPNA1
gene id: 89673:KPNA1
uniprot id: A0A6J2L0N9
names: Function
names: Similarity
messages: Belongs to the importin alpha family.
messages: Functions in nuclear protein import.

89673:LOC114498484
gene id: 89673:LOC114498484
uniprot id: A0A7E6E2U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:NPY
gene id: 89673:NPY
uniprot id: A0A6J2MV68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

89673:SEC22A
gene id: 89673:SEC22A
uniprot id: A0A6J2L578
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in vesicle transport between the ER and the Golgi complex.
messages: Membrane

89673:PGM2
gene id: 89673:PGM2
uniprot id: A0A6J2L761
names: Similarity
messages: Belongs to the phosphohexose mutase family.

89673:IL17RD
gene id: 89673:IL17RD
uniprot id: A0A6J2M3P8
uniprot id: A0A7E6E629
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114503455
gene id: 89673:LOC114503455
uniprot id: A0A6J2MEX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

89673:TRPV6
gene id: 89673:TRPV6
uniprot id: A0A6J2MTN0
uniprot id: A0A7E6CIV1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:POP4
gene id: 89673:POP4
uniprot id: A0A6J2L0P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Component of nuclear RNase P and RNase MRP.
messages: Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends.
messages: nucleolus

89673:LOC114495042
gene id: 89673:LOC114495042
uniprot id: A0A7E6DHF0
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

89673:ALDH3A1
gene id: 89673:ALDH3A1
uniprot id: A0A7E6EB35
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

89673:MFSD6L
gene id: 89673:MFSD6L
uniprot id: A0A6J2NER6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. MFSD6 family.
messages: Membrane

89673:CAMTA2
gene id: 89673:CAMTA2
uniprot id: A0A6J2NDD1
uniprot id: A0A6J2NF10
uniprot id: A0A6J2NF15
uniprot id: A0A6J2NFD9
uniprot id: A0A6J2NJM4
uniprot id: A0A6J2NJM6
uniprot id: A0A6J2NJW6
uniprot id: A0A7E6EDE9
names: Similarity
names: Subunit
messages: Belongs to the CAMTA family.
messages: May interact with calmodulin.

89673:PPFIA1
gene id: 89673:PPFIA1
uniprot id: A0A7E6E2E4
uniprot id: A0A7E6E2X9
uniprot id: A0A7E6E2Y3
uniprot id: A0A7E6E362
uniprot id: A0A7E6E365
uniprot id: A0A7E6E3V0
uniprot id: A0A7E6E3W0
uniprot id: A0A7E6E3W8
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

89673:ADAM15
gene id: 89673:ADAM15
uniprot id: A0A6J2KTP6
uniprot id: A0A6J2KVA3
uniprot id: A0A6J2KVB0
uniprot id: A0A6J2KWZ0
uniprot id: A0A6J2KZ35
uniprot id: A0A7E6CV36
uniprot id: A0A7E6CV43
uniprot id: A0A7E6CVK8
uniprot id: A0A7E6CVU8
uniprot id: A0A7E6CVV5
uniprot id: A0A7E6CXW7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:ADGRE1
gene id: 89673:ADGRE1
uniprot id: A0A7E6E9Y2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:LOC118499395
gene id: 89673:LOC118499395
uniprot id: A0A7E6DAN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

89673:CHAC1
gene id: 89673:CHAC1
uniprot id: A0A7E6E859
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

89673:LOC114500303
gene id: 89673:LOC114500303
uniprot id: A0A6J2LZI3
uniprot id: A0A7E6DWB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:DIS3
gene id: 89673:DIS3
uniprot id: A0A6J2MRV1
names: Similarity
messages: Belongs to the RNR ribonuclease family.

89673:TERT
gene id: 89673:TERT
uniprot id: A0A6J2LMK3
uniprot id: A0A7E6DA29
uniprot id: A0A7E6DAF5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reverse transcriptase family. Telomerase subfamily.
messages: Cytoplasm
messages: Nucleus
messages: PML body
messages: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nucleotide telomeric repeat unit, 5'-TTAGGG-3'. The catalytic cycle involves primer binding, primer extension and release of product once the template boundary has been reached or nascent product translocation followed by further extension. More active on substrates containing 2 or 3 telomeric repeats. Telomerase activity is regulated by a number of factors including telomerase complex-associated proteins, chaperones and polypeptide modifiers. Modulates Wnt signaling. Plays important roles in aging and antiapoptosis.
messages: The RNA-interacting domain 1 (RD1)/N-terminal extension (NTE) is required for interaction with the pseudoknot-template domain of each of TERC dimers. It contains anchor sites that bind primer nucleotides upstream of the RNA-DNA hybrid and is thus an essential determinant of repeat addition processivity.
messages: The RNA-interacting domain 2 (RD2) is essential for both interaction with the CR4-CR5 domain of TERC and for DNA synthesis.
messages: The primer grip sequence in the RT domain is required for telomerase activity and for stable association with short telomeric primers.
messages: nucleolus
messages: nucleoplasm
messages: telomere

89673:KIF27
gene id: 89673:KIF27
uniprot id: A0A6J2LYE8
uniprot id: A0A7E6DFB7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

89673:ATL3
gene id: 89673:ATL3
uniprot id: A0A6J2LVY4
uniprot id: A0A6J2LWW8
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

89673:DYNLRB1
gene id: 89673:DYNLRB1
uniprot id: A0A6J2MQ55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
messages: Belongs to the GAMAD family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs); the composition seems to vary in respect to the IC, LIC and LC composition. The heavy chain homodimer serves as a scaffold for the probable homodimeric assembly of the respective non-catalytic subunits. The ICs and LICs bind directly to the HC dimer and the LCs assemble on the IC dimer.
messages: cytoskeleton

89673:USP48
gene id: 89673:USP48
uniprot id: A0A6J2LIN2
uniprot id: A0A6J2LN38
uniprot id: A0A7E6DQB2
uniprot id: A0A7E6DR19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Nucleus

89673:PARP15
gene id: 89673:PARP15
uniprot id: A0A7E6D470
uniprot id: A0A7E6D4B7
uniprot id: A0A7E6D4E1
uniprot id: A0A7E6D706
names: Similarity
messages: Belongs to the ARTD/PARP family.

89673:LOC114490167
gene id: 89673:LOC114490167
uniprot id: A0A6J2KZ54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:HTATSF1
gene id: 89673:HTATSF1
uniprot id: A0A6J2MFI3
names: Similarity
messages: Belongs to the HTATSF1 family.

89673:GDI1
gene id: 89673:GDI1
uniprot id: A0A6J2MKQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

89673:TAF5L
gene id: 89673:TAF5L
uniprot id: A0A6J2NAJ0
uniprot id: A0A7E6CY91
uniprot id: A0A7E6CYM3
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

89673:PPP3CB
gene id: 89673:PPP3CB
uniprot id: A0A6J2LNU9
uniprot id: A0A6J2LQ38
uniprot id: A0A6J2LR34
uniprot id: A0A6J2LU77
uniprot id: A0A6J2LU82
uniprot id: A0A7E6DU54
uniprot id: A0A7E6DVA8
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

89673:SGSM1
gene id: 89673:SGSM1
uniprot id: A0A6J2N2C5
uniprot id: A0A7E6CUF3
uniprot id: A0A7E6CV88
uniprot id: A0A7E6CX84
names: Similarity
messages: Belongs to the RUTBC family.

89673:LOC114513052
gene id: 89673:LOC114513052
uniprot id: A0A6J2N7U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TMEM120A
gene id: 89673:TMEM120A
uniprot id: A0A6J2MUR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM120 family.
messages: Membrane
messages: Nucleus inner membrane

89673:SCRN1
gene id: 89673:SCRN1
uniprot id: A0A6J2MMB9
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

89673:ANO10
gene id: 89673:ANO10
uniprot id: A0A6J2M4H3
uniprot id: A0A6J2M793
uniprot id: A0A7E6E4Q6
uniprot id: A0A7E6E4V1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:CYRIB
gene id: 89673:CYRIB
uniprot id: A0A6J2NCW2
uniprot id: A0A6J2NI21
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CYRI family.
messages: Interacts with RAC1 (GTP-bound form preferentially).
messages: Membrane

89673:ECRG4
gene id: 89673:ECRG4
uniprot id: A0A6J2M4H0
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the augurin family.
messages: Cytoplasm
messages: Membrane
messages: Secreted

89673:LOC114489882
gene id: 89673:LOC114489882
uniprot id: A0A7E6D1L2
uniprot id: A0A7E6D1M8
uniprot id: A0A7E6D1Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

89673:CUL4A
gene id: 89673:CUL4A
uniprot id: A0A6J2MRL2
names: Similarity
messages: Belongs to the cullin family.

89673:PDE10A
gene id: 89673:PDE10A
uniprot id: A0A6J2KWM2
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

89673:RIPOR3
gene id: 89673:RIPOR3
uniprot id: A0A6J2MQU7
names: Similarity
messages: Belongs to the RIPOR family.

89673:NKAIN3
gene id: 89673:NKAIN3
uniprot id: A0A6J2NIT8
uniprot id: A0A7E6E6M9
uniprot id: A0A7E6E7S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

89673:SLC24A3
gene id: 89673:SLC24A3
uniprot id: A0A6J2MP11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

89673:C3H5orf63
gene id: 89673:C3H5orf63
uniprot id: A0A6J2N8E4
names: Similarity
messages: Belongs to the glutaredoxin family.

89673:CAPZA2
gene id: 89673:CAPZA2
uniprot id: A0A6J2MP20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

89673:SCG2
gene id: 89673:SCG2
uniprot id: A0A6J2LL99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Interacts with Secretogranin III/SCG3.
messages: Neuroendocrine protein of the granin family that regulates the biogenesis of secretory granules.
messages: Secreted

89673:SELENOM
gene id: 89673:SELENOM
uniprot id: A0A6J2MWH3
names: Similarity
messages: Belongs to the selenoprotein M/F family.

89673:TBC1D31
gene id: 89673:TBC1D31
uniprot id: A0A6J2ND74
names: Function
names: Subcellular Location Annotation
messages: Molecular adapter which is involved in cilium biogenesis. Part of a functional complex including OFD1 a centriolar protein involved in cilium assembly. Could regulate the cAMP-dependent phosphorylation of OFD1, and its subsequent ubiquitination by PJA2 which ultimately leads to its proteasomal degradation.
messages: centriolar satellite
messages: cilium basal body

89673:EFNB1
gene id: 89673:EFNB1
uniprot id: A0A6J2MJZ0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:KCND1
gene id: 89673:KCND1
uniprot id: A0A6J2MGR7
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

89673:LOC114505968
gene id: 89673:LOC114505968
uniprot id: A0A7E6CGA6
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

89673:LOC114491878
gene id: 89673:LOC114491878
uniprot id: A0A6J2L2S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

89673:DYNC2LI1
gene id: 89673:DYNC2LI1
uniprot id: A0A6J2LY61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light intermediate chain family.
messages: centrosome
messages: cilium
messages: cilium axoneme
messages: cilium basal body

89673:ZDHHC15
gene id: 89673:ZDHHC15
uniprot id: A0A6J2ME05
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

89673:LOC114489254
gene id: 89673:LOC114489254
uniprot id: A0A6J2KV50
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:KCNT1
gene id: 89673:KCNT1
uniprot id: A0A6J2MK18
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:IGF2BP3
gene id: 89673:IGF2BP3
uniprot id: A0A6J2MTB7
uniprot id: A0A7E6CJH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM IMP/VICKZ family.
messages: P-body
messages: Stress granule

89673:CNR1
gene id: 89673:CNR1
uniprot id: A0A6J2LFX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for cannabinoids, including endocannabinoids (eCBs), such as N-arachidonoylethanolamide (also called anandamide or AEA) and 2-arachidonoylglycerol (2-AG). Signaling typically involves reduction in cyclic AMP.
messages: Interacts (via C-terminus) with CNRIP1.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Presynapse
messages: Synapse
messages: axon

89673:LOC114510650
gene id: 89673:LOC114510650
uniprot id: A0A7E6CQ93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

89673:CDK4
gene id: 89673:CDK4
uniprot id: A0A6J2NBY6
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:TBX22
gene id: 89673:TBX22
uniprot id: A0A6J2MKQ6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

89673:SCD5
gene id: 89673:SCD5
uniprot id: A0A6J2L4E1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

89673:CCL17
gene id: 89673:CCL17
uniprot id: A0A6J2KX84
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.

89673:ACAP1
gene id: 89673:ACAP1
uniprot id: A0A6J2NJI6
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

89673:GPR137B
gene id: 89673:GPR137B
uniprot id: A0A6J2N5R3
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

89673:GSC
gene id: 89673:GSC
uniprot id: A0A6J2L729
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114507843
gene id: 89673:LOC114507843
uniprot id: A0A6J2MQ82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC118499946
gene id: 89673:LOC118499946
uniprot id: A0A7E6DHK6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:PTPN6
gene id: 89673:PTPN6
uniprot id: A0A6J2N7T5
uniprot id: A0A7E6D2N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm

89673:CAV2
gene id: 89673:CAV2
uniprot id: A0A6J2MPJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

89673:RPS6KA1
gene id: 89673:RPS6KA1
uniprot id: A0A6J2LI62
uniprot id: A0A6J2LKJ0
uniprot id: A0A6J2LN43
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

89673:LOC114506325
gene id: 89673:LOC114506325
uniprot id: A0A7E6CE51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ATPase B chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion
messages: Mitochondrion inner membrane

89673:GGA3
gene id: 89673:GGA3
uniprot id: A0A6J2MEA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

89673:TM2D1
gene id: 89673:TM2D1
uniprot id: A0A7E6DS90
uniprot id: A0A7E6DTG8
names: Subcellular Location Annotation
messages: Membrane

89673:EXOC6B
gene id: 89673:EXOC6B
uniprot id: A0A6J2LU70
uniprot id: A0A6J2LX59
uniprot id: A0A6J2LX64
uniprot id: A0A7E6DXL8
uniprot id: A0A7E6DXQ9
uniprot id: A0A7E6DY49
uniprot id: A0A7E6DYJ9
names: Function
names: Similarity
messages: Belongs to the SEC15 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

89673:WNT9B
gene id: 89673:WNT9B
uniprot id: A0A6J2MGS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

89673:SHKBP1
gene id: 89673:SHKBP1
uniprot id: A0A6J2N1E2
uniprot id: A0A7E6CNU0
names: Similarity
messages: Belongs to the KCTD3 family.

89673:PFN3
gene id: 89673:PFN3
uniprot id: A0A7E6CSL8
names: Similarity
messages: Belongs to the profilin family.

89673:STEAP1
gene id: 89673:STEAP1
uniprot id: A0A6J2MPN8
uniprot id: A0A7E6CHU3
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114493370
gene id: 89673:LOC114493370
uniprot id: A0A7E6E308
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

89673:SERPINE1
gene id: 89673:SERPINE1
uniprot id: A0A6J2LIV3
names: Similarity
messages: Belongs to the serpin family.

89673:LSM3
gene id: 89673:LSM3
uniprot id: A0A6J2M7I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

89673:LOC114512991
gene id: 89673:LOC114512991
uniprot id: A0A6J2N5W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:PRF1
gene id: 89673:PRF1
uniprot id: A0A6J2LRA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Secreted

89673:LSM6
gene id: 89673:LSM6
uniprot id: A0A6J2MB40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

89673:SDHAF2
gene id: 89673:SDHAF2
uniprot id: A0A6J2LYN7
uniprot id: A0A7E6E1K3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SDHAF2 family.
messages: Interacts with SDHA within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer.

89673:LOC114502708
gene id: 89673:LOC114502708
uniprot id: A0A6J2M5G6
names: Function
messages: Synthesizes selenophosphate from selenide and ATP.

89673:NME6
gene id: 89673:NME6
uniprot id: A0A6J2M569
uniprot id: A0A7E6E4H3
names: Similarity
messages: Belongs to the NDK family.

89673:CMTM8
gene id: 89673:CMTM8
uniprot id: A0A6J2M285
names: Subcellular Location Annotation
messages: Membrane

89673:GRAMD1C
gene id: 89673:GRAMD1C
uniprot id: A0A7E6D449
uniprot id: A0A7E6D6S7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:PLD4
gene id: 89673:PLD4
uniprot id: A0A7E6CSX5
names: Similarity
messages: Belongs to the phospholipase D family.

89673:B3GALNT1
gene id: 89673:B3GALNT1
uniprot id: A0A6J2L0L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

89673:PPY
gene id: 89673:PPY
uniprot id: A0A6J2M483
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

89673:CHD8
gene id: 89673:CHD8
uniprot id: A0A7E6E6L1
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. CHD8 subfamily.
messages: DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive genes. Involved in both enhancer blocking and epigenetic remodeling at chromatin boundary via its interaction with CTCF. Acts as a suppressor of STAT3 activity by suppressing the LIF-induced STAT3 transcriptional activity. Also acts as a transcription activator via its interaction with ZNF143 by participating in efficient U6 RNA polymerase III transcription.
messages: Interacts with p53/TP53, histone H1, CTNNB1, CTCF and PIAS3. Component of some MLL1/MLL complex, at least composed of the core components KMT2A/MLL1, ASH2L, HCFC1/HCF1, WDR5 and RBBP5, as well as the facultative components BAP18, CHD8, E2F6, HSP70, INO80C, KANSL1, LAS1L, MAX, MCRS1, MGA, KAT8/MOF, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 and TEX10. Interacts with CHD7. Interacts with FAM124B.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Sumoylated.

89673:TMEM176B
gene id: 89673:TMEM176B
uniprot id: A0A6J2MUT8
names: Similarity
messages: Belongs to the TMEM176 family.

89673:FMN1
gene id: 89673:FMN1
uniprot id: A0A7E6D1G2
names: Similarity
messages: Belongs to the formin homology family. Cappuccino subfamily.

89673:LOC114510032
gene id: 89673:LOC114510032
uniprot id: A0A6J2MWF9
uniprot id: A0A7E6CS87
uniprot id: A0A7E6CS93
uniprot id: A0A7E6CS94
uniprot id: A0A7E6CSN1
uniprot id: A0A7E6CSX9
uniprot id: A0A7E6CUY1
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. TRA1 subfamily.

89673:PAIP2B
gene id: 89673:PAIP2B
uniprot id: A0A6J2M0X7
names: Similarity
messages: Belongs to the PAIP2 family.

89673:OCLN
gene id: 89673:OCLN
uniprot id: A0A6J2MCZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
messages: Membrane
messages: tight junction

89673:MYO9B
gene id: 89673:MYO9B
uniprot id: A0A6J2MIP8
uniprot id: A0A7E6E9S4
uniprot id: A0A7E6E9S9
uniprot id: A0A7E6EAK4
uniprot id: A0A7E6EAK9
uniprot id: A0A7E6EAL4
uniprot id: A0A7E6EAS3
uniprot id: A0A7E6EAS9
uniprot id: A0A7E6EBE9
uniprot id: A0A7E6EBF0
uniprot id: A0A7E6EBT2
uniprot id: A0A7E6EBU4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

89673:PPP2R5D
gene id: 89673:PPP2R5D
uniprot id: A0A6J2LGI1
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

89673:LOC114513387
gene id: 89673:LOC114513387
uniprot id: A0A6J2N9A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:EIF3D
gene id: 89673:EIF3D
uniprot id: A0A6J2NAF4
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit D family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3.
messages: Cytoplasm
messages: Phosphorylated upon DNA damage, probably by ATM or ATR.
messages: The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. In the eIF-3 complex, EIF3D specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.

89673:A1CF
gene id: 89673:A1CF
uniprot id: A0A6J2LP93
uniprot id: A0A7E6DW98
uniprot id: A0A7E6DWN7
uniprot id: A0A7E6DXI4
names: Subcellular Location Annotation
messages: Cytoplasm

89673:SLC27A5
gene id: 89673:SLC27A5
uniprot id: A0A6J2N1F0
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

89673:DIAPH3
gene id: 89673:DIAPH3
uniprot id: A0A6J2MSU4
uniprot id: A0A6J2MXD1
names: Similarity
messages: Belongs to the formin homology family. Diaphanous subfamily.

89673:SAR1A
gene id: 89673:SAR1A
uniprot id: A0A6J2LKR6
names: Similarity
messages: Belongs to the small GTPase superfamily. SAR1 family.

89673:MYO5A
gene id: 89673:MYO5A
uniprot id: A0A6J2L958
uniprot id: A0A7E6EDQ8
uniprot id: A0A7E6EDX6
uniprot id: A0A7E6EDY1
uniprot id: A0A7E6EEQ6
uniprot id: A0A7E6EF01
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

89673:DNAJA1
gene id: 89673:DNAJA1
uniprot id: A0A6J2LCC0
names: Subcellular Location Annotation
messages: Membrane

89673:SLC25A45
gene id: 89673:SLC25A45
uniprot id: A0A6J2LWH6
uniprot id: A0A7E6E3H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

89673:FAM234A
gene id: 89673:FAM234A
uniprot id: A0A6J2MTC4
names: Similarity
messages: Belongs to the FAM234 family.

89673:SHANK1
gene id: 89673:SHANK1
uniprot id: A0A6J2N2G2
uniprot id: A0A7E6CNI3
uniprot id: A0A7E6CQX1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.
messages: Postsynaptic density

89673:LOC114503717
gene id: 89673:LOC114503717
uniprot id: A0A6J2MCY8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:PDE7A
gene id: 89673:PDE7A
uniprot id: A0A6J2NC02
uniprot id: A0A6J2NHT9
uniprot id: A0A7E6E6N2
uniprot id: A0A7E6E7S3
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

89673:RBP5
gene id: 89673:RBP5
uniprot id: A0A6J2N9L7
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

89673:TBCC
gene id: 89673:TBCC
uniprot id: A0A6J2LK99
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCC family.
messages: Cytoplasm
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.

89673:F13B
gene id: 89673:F13B
uniprot id: A0A6J2NAI9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114504322
gene id: 89673:LOC114504322
uniprot id: A0A7E6EEG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

89673:LOC114494143
gene id: 89673:LOC114494143
uniprot id: A0A6J2LGJ8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.

89673:PPP2R5A
gene id: 89673:PPP2R5A
uniprot id: A0A6J2N3D5
uniprot id: A0A7E6CWA4
uniprot id: A0A7E6CWK7
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

89673:ACTR10
gene id: 89673:ACTR10
uniprot id: A0A6J2L5N0
names: Similarity
messages: Belongs to the actin family.

89673:RPS18
gene id: 89673:RPS18
uniprot id: A0A6J2LGI8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Component of the small ribosomal subunit.

89673:LOC114500132
gene id: 89673:LOC114500132
uniprot id: A0A6J2LYW5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

89673:SLC25A37
gene id: 89673:SLC25A37
uniprot id: A0A6J2MBF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

89673:TULP2
gene id: 89673:TULP2
uniprot id: A0A7E6CPE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUB family.
messages: Secreted

89673:MANEAL
gene id: 89673:MANEAL
uniprot id: A0A6J2LQQ8
uniprot id: A0A7E6DR40
uniprot id: A0A7E6DRV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

89673:ABRAXAS1
gene id: 89673:ABRAXAS1
uniprot id: A0A6J2L5M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM175 family. Abraxas subfamily.
messages: Nucleus

89673:LOC114500714
gene id: 89673:LOC114500714
uniprot id: A0A6J2LZV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:EME2
gene id: 89673:EME2
uniprot id: A0A6J2MI16
uniprot id: A0A7E6DCC9
uniprot id: A0A7E6DDM8
names: Similarity
messages: Belongs to the EME1/MMS4 family.

89673:UNK
gene id: 89673:UNK
uniprot id: A0A6J2MC63
uniprot id: A0A7E6EGD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unkempt family.
messages: Cytoplasm

89673:LOC114488218
gene id: 89673:LOC114488218
uniprot id: A0A6J2KR40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Golgi apparatus
messages: May play an important role in formation and fusion of Golgi-derived vesicles during acrosome biogenesis.
messages: Nucleus
messages: cytoskeleton

89673:GPR37
gene id: 89673:GPR37
uniprot id: A0A6J2MQU8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:SLC25A46
gene id: 89673:SLC25A46
uniprot id: A0A6J2LRB7
uniprot id: A0A6J2LTE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion outer membrane

89673:TXLNA
gene id: 89673:TXLNA
uniprot id: A0A6J2LNJ7
uniprot id: A0A7E6DQU3
names: Similarity
messages: Belongs to the taxilin family.

89673:RETNLB
gene id: 89673:RETNLB
uniprot id: A0A6J2KSI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistin/FIZZ family.
messages: Secreted

89673:GFRA4
gene id: 89673:GFRA4
uniprot id: A0A7E6CEC1
names: Similarity
messages: Belongs to the GDNFR family.

89673:NUSAP1
gene id: 89673:NUSAP1
uniprot id: A0A6J2L4X0
uniprot id: A0A7E6E958
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NUSAP family.
messages: Cytoplasm

89673:OPRD1
gene id: 89673:OPRD1
uniprot id: A0A6J2LNT5
uniprot id: A0A7E6DQN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:MYO18B
gene id: 89673:MYO18B
uniprot id: A0A7E6CRB1
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:CROT
gene id: 89673:CROT
uniprot id: A0A6J2MR03
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

89673:GALM
gene id: 89673:GALM
uniprot id: A0A6J2LX22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldose epimerase family.
messages: Monomer.
messages: Mutarotase that catalyzes the interconversion of beta-D-galactose and alpha-D-galactose during galactose metabolism.

89673:LOC114501005
gene id: 89673:LOC114501005
uniprot id: A0A6J2M2N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SPSB4
gene id: 89673:SPSB4
uniprot id: A0A6J2M4R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

89673:TMEM106C
gene id: 89673:TMEM106C
uniprot id: A0A6J2ND36
names: Similarity
messages: Belongs to the TMEM106 family.

89673:LOC114503779
gene id: 89673:LOC114503779
uniprot id: A0A6J2MGP2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:USP37
gene id: 89673:USP37
uniprot id: A0A6J2LC31
uniprot id: A0A7E6DI79
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

89673:LOC114488868
gene id: 89673:LOC114488868
uniprot id: A0A6J2KV50
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:EMC9
gene id: 89673:EMC9
uniprot id: A0A6J2L529
names: Similarity
messages: Belongs to the EMC8/EMC9 family.

89673:LOC114507847
gene id: 89673:LOC114507847
uniprot id: A0A6J2MQ87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LGR5
gene id: 89673:LGR5
uniprot id: A0A6J2NBR9
names: Subcellular Location Annotation
messages: Membrane

89673:EXOC1
gene id: 89673:EXOC1
uniprot id: A0A6J2L0V3
uniprot id: A0A6J2L1J1
uniprot id: A0A6J2L390
uniprot id: A0A6J2L6I9
uniprot id: A0A7E6DBF5
uniprot id: A0A7E6DDH1
uniprot id: A0A7E6DDH3
names: Similarity
messages: Belongs to the SEC3 family.

89673:LOC114499564
gene id: 89673:LOC114499564
uniprot id: A0A7E6DXI0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

89673:ARRB1
gene id: 89673:ARRB1
uniprot id: A0A6J2LVB1
uniprot id: A0A6J2LXC5
uniprot id: A0A6J2M0A4
uniprot id: A0A7E6DZR9
uniprot id: A0A7E6DZS5
uniprot id: A0A7E6E0Y6
names: Similarity
messages: Belongs to the arrestin family.

89673:SLC25A10
gene id: 89673:SLC25A10
uniprot id: A0A6J2MBP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

89673:ATP5IF1
gene id: 89673:ATP5IF1
uniprot id: A0A6J2LNI2
uniprot id: A0A6J2LSI3
uniprot id: A0A7E6DQL4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase inhibitor family.
messages: Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase.
messages: Forms an alpha-helical dimer with monomers associated via an antiparallel alpha-helical coiled coil, leaving each N-terminal inhibitory region accessible for interaction with an F1 catalytic domain. The inhibitory N-terminal region binds the alpha(ADP-bound)-beta(ADP-bound) (ATP5F1A-ATP5F1B) interface of F1-ATPase, and also contact the central gamma subunit (ATP5F1C). This dimeric state is favored by pH values below 7.0, and at higher values the dimers associate to form inactive homotetramer, where the inhibitory region is occluded, masking its inhibitory activity.
messages: Homodimer; represents the active form and is present at a pH value below 6.5. Homotetramer; represents the inactive form and is present at a pH value above 7.0.
messages: Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing fech to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme.
messages: Mitochondrion

89673:HSD17B1
gene id: 89673:HSD17B1
uniprot id: A0A7E6EEK1
uniprot id: A0A7E6EER8
uniprot id: A0A7E6EFR0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

89673:LOC114500345
gene id: 89673:LOC114500345
uniprot id: A0A6J2LZQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114490247
gene id: 89673:LOC114490247
uniprot id: A0A6J2L132
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

89673:RPS11
gene id: 89673:RPS11
uniprot id: A0A6J2N0E8
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

89673:HOXA3
gene id: 89673:HOXA3
uniprot id: A0A6J2MPF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

89673:EDN2
gene id: 89673:EDN2
uniprot id: A0A6J2LR21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

89673:PARN
gene id: 89673:PARN
uniprot id: A0A6J2LNK8
uniprot id: A0A7E6DBP5
uniprot id: A0A7E6DDJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Cytoplasm

89673:CHST9
gene id: 89673:CHST9
uniprot id: A0A6J2MQJ1
uniprot id: A0A7E6CDK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

89673:PKN1
gene id: 89673:PKN1
uniprot id: A0A6J2M674
uniprot id: A0A6J2M7M2
uniprot id: A0A6J2M826
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cleavage furrow
messages: Midbody
messages: Nucleus

89673:SLC25A42
gene id: 89673:SLC25A42
uniprot id: A0A6J2MBI4
uniprot id: A0A6J2MEQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

89673:SS18L1
gene id: 89673:SS18L1
uniprot id: A0A6J2MIG1
names: Similarity
messages: Belongs to the SS18 family.

89673:BAIAP2
gene id: 89673:BAIAP2
uniprot id: A0A6J2M8B8
uniprot id: A0A7E6EFF0
uniprot id: A0A7E6EFR6
names: Function
names: Subcellular Location Annotation
messages: Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions.
messages: Membrane
messages: cytoskeleton
messages: filopodium
messages: ruffle

89673:MTERF1
gene id: 89673:MTERF1
uniprot id: A0A6J2MPA3
names: Similarity
messages: Belongs to the mTERF family.

89673:GGT5
gene id: 89673:GGT5
uniprot id: A0A7E6CU60
names: Similarity
messages: Belongs to the gamma-glutamyltransferase family.

89673:LOC114489781
gene id: 89673:LOC114489781
uniprot id: A0A6J2KVL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC118499272
gene id: 89673:LOC118499272
uniprot id: A0A7E6DCB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

89673:LOC114506226
gene id: 89673:LOC114506226
uniprot id: A0A7E6D9Q6
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

89673:PHB2
gene id: 89673:PHB2
uniprot id: A0A6J2NEW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

89673:ARHGEF1
gene id: 89673:ARHGEF1
uniprot id: A0A7E6CP24
uniprot id: A0A7E6CP35
uniprot id: A0A7E6CPA0
uniprot id: A0A7E6CRH8
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114515372
gene id: 89673:LOC114515372
uniprot id: A0A7E6EFG0
names: Similarity
messages: Belongs to the NAC-beta family.

89673:LOC114488685
gene id: 89673:LOC114488685
uniprot id: A0A6J2KSR7
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114492971
gene id: 89673:LOC114492971
uniprot id: A0A6J2LCV3
names: Subcellular Location Annotation
messages: Membrane

89673:PSMB9
gene id: 89673:PSMB9
uniprot id: A0A6J2LGW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

89673:CANX
gene id: 89673:CANX
uniprot id: A0A6J2MTV4
names: Similarity
messages: Belongs to the calreticulin family.

89673:ALOX15
gene id: 89673:ALOX15
uniprot id: A0A7E6EDK5
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:HAUS1
gene id: 89673:HAUS1
uniprot id: A0A6J2MQC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS1 family.
messages: spindle

89673:LOC114499275
gene id: 89673:LOC114499275
uniprot id: A0A6J2LVS8
names: Similarity
messages: Belongs to the FAM178 family.

89673:USP4
gene id: 89673:USP4
uniprot id: A0A6J2M509
uniprot id: A0A6J2M7U6
uniprot id: A0A7E6E3U2
uniprot id: A0A7E6E5G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: Nucleus

89673:RBP2
gene id: 89673:RBP2
uniprot id: A0A6J2M992
uniprot id: A0A7E6E4U3
uniprot id: A0A7E6E6E6
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

89673:SNED1
gene id: 89673:SNED1
uniprot id: A0A7E6DPQ4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:SULF2
gene id: 89673:SULF2
uniprot id: A0A6J2MRB6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin.
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

89673:MYO1F
gene id: 89673:MYO1F
uniprot id: A0A6J2ME60
uniprot id: A0A7E6EB54
uniprot id: A0A7E6EBB5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

89673:CPD
gene id: 89673:CPD
uniprot id: A0A6J2MDF9
names: Similarity
messages: Belongs to the peptidase M14 family.

89673:LOC114490203
gene id: 89673:LOC114490203
uniprot id: A0A6J2L2S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TUBB1
gene id: 89673:TUBB1
uniprot id: A0A6J2MIX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

89673:LOC114490240
gene id: 89673:LOC114490240
uniprot id: A0A6J2KZD2
uniprot id: A0A7E6CGX1
uniprot id: A0A7E6CH76
uniprot id: A0A7E6CHE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

89673:SCN3A
gene id: 89673:SCN3A
uniprot id: A0A6J2LC09
uniprot id: A0A6J2LCZ4
uniprot id: A0A6J2LFZ6
uniprot id: A0A6J2LGZ0
uniprot id: A0A6J2LGZ9
uniprot id: A0A7E6DJU9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

89673:SEC24A
gene id: 89673:SEC24A
uniprot id: A0A6J2MU22
uniprot id: A0A6J2MU27
uniprot id: A0A6J2MZ37
uniprot id: A0A7E6CSA8
uniprot id: A0A7E6CUZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

89673:HSPB3
gene id: 89673:HSPB3
uniprot id: A0A6J2L413
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: Nucleus

89673:LOC114503588
gene id: 89673:LOC114503588
uniprot id: A0A6J2MFJ9
uniprot id: A0A7E6DCS5
names: Function
names: Similarity
messages: Belongs to the TYW1 family.
messages: Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis.

89673:ATP6AP1
gene id: 89673:ATP6AP1
uniprot id: A0A6J2MH29
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

89673:FGF10
gene id: 89673:FGF10
uniprot id: A0A6J2M402
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

89673:GKAP1
gene id: 89673:GKAP1
uniprot id: A0A6J2MMA5
uniprot id: A0A7E6DF64
uniprot id: A0A7E6DF96
uniprot id: A0A7E6DF97
uniprot id: A0A7E6DFB2
names: Similarity
messages: Belongs to the GKAP1 family.

89673:MRPS18C
gene id: 89673:MRPS18C
uniprot id: A0A6J2L7S4
uniprot id: A0A6J2LAC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Mitochondrion

89673:PPP1R13B
gene id: 89673:PPP1R13B
uniprot id: A0A7E6D2P1
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114503409
gene id: 89673:LOC114503409
uniprot id: A0A6J2MF54
names: Function
names: Subcellular Location Annotation
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.
messages: Mitochondrion inner membrane

89673:E2F6
gene id: 89673:E2F6
uniprot id: A0A6J2LYK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

89673:SERPINF1
gene id: 89673:SERPINF1
uniprot id: A0A6J2MHE6
names: Similarity
messages: Belongs to the serpin family.

89673:KCNA5
gene id: 89673:KCNA5
uniprot id: A0A6J2N9P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.5/KCNA5 sub-subfamily.
messages: Cell membrane
messages: Membrane

89673:CDK2AP2
gene id: 89673:CDK2AP2
uniprot id: A0A6J2LYW9
uniprot id: A0A6J2M4F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDK2AP family.
messages: Nucleus

89673:MLLT3
gene id: 89673:MLLT3
uniprot id: A0A6J2MFZ2
names: Subcellular Location Annotation
messages: Nucleus

89673:PIH1D1
gene id: 89673:PIH1D1
uniprot id: A0A6J2N1K2
uniprot id: A0A7E6CNI6
names: Similarity
messages: Belongs to the PIH1 family.

89673:CCN3
gene id: 89673:CCN3
uniprot id: A0A6J2NB71
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:CEP170
gene id: 89673:CEP170
uniprot id: A0A6J2N363
uniprot id: A0A6J2N4X0
uniprot id: A0A6J2N9H4
uniprot id: A0A7E6CYA3
uniprot id: A0A7E6CYA7
uniprot id: A0A7E6CYF3
uniprot id: A0A7E6CYQ8
uniprot id: A0A7E6CYR3
uniprot id: A0A7E6CZ80
uniprot id: A0A7E6D0X7
uniprot id: A0A7E6D0Y2
names: Similarity
messages: Belongs to the CEP170 family.

89673:CPNE2
gene id: 89673:CPNE2
uniprot id: A0A6J2KUX7
names: Similarity
messages: Belongs to the copine family.

89673:TMEM150A
gene id: 89673:TMEM150A
uniprot id: A0A6J2LRF8
uniprot id: A0A7E6DZH1
names: Subcellular Location Annotation
messages: Membrane

89673:ATP7A
gene id: 89673:ATP7A
uniprot id: A0A6J2MHB6
uniprot id: A0A7E6D089
uniprot id: A0A7E6D161
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane
messages: trans-Golgi network membrane

89673:GATB
gene id: 89673:GATB
uniprot id: A0A6J2MHD0
uniprot id: A0A7E6E920
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

89673:ADRB2
gene id: 89673:ADRB2
uniprot id: A0A6J2MWU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB2 sub-subfamily.
messages: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.
messages: Cell membrane
messages: Early endosome
messages: Golgi apparatus
messages: Membrane

89673:PDGFA
gene id: 89673:PDGFA
uniprot id: A0A6J2N4D2
uniprot id: A0A7E6CRN1
uniprot id: A0A7E6CRZ4
uniprot id: A0A7E6CS72
uniprot id: A0A7E6CS77
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

89673:STC1
gene id: 89673:STC1
uniprot id: A0A6J2MDQ2
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.

89673:NDUFA11
gene id: 89673:NDUFA11
uniprot id: A0A6J2MCB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA11 subunit family.
messages: Mitochondrion inner membrane

89673:LOC114498879
gene id: 89673:LOC114498879
uniprot id: A0A6J2LSG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114506770
gene id: 89673:LOC114506770
uniprot id: A0A6J2MM02
names: Similarity
messages: Belongs to the vasopressin/oxytocin family.

89673:P2RY13
gene id: 89673:P2RY13
uniprot id: A0A7E6D3J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:VCAN
gene id: 89673:VCAN
uniprot id: A0A6J2N282
uniprot id: A0A7E6DAM5
uniprot id: A0A7E6DD92
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aggrecan/versican proteoglycan family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

89673:GABRD
gene id: 89673:GABRD
uniprot id: A0A6J2LRL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

89673:UNC5A
gene id: 89673:UNC5A
uniprot id: A0A6J2MVW1
uniprot id: A0A7E6CT20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

89673:LOC114497911
gene id: 89673:LOC114497911
uniprot id: A0A6J2LUW6
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: Involved in oxygen transport from the lung to the various peripheral tissues.
messages: The zeta chain is an alpha-type chain of mammalian embryonic hemoglobin.

89673:BDNF
gene id: 89673:BDNF
uniprot id: A0A6J2M2C1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NGF-beta family.
messages: During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.
messages: Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
messages: Monomers and homodimers (By similarity). Binds to NTRK2/TRKB. Can form heterodimers with other neurotrophin family members, such as NTF3 and NTF4 (in vitro), but the physiological relevance of this is not clear (By similarity). BDNF precursor form: interacts with the heterodimer formed by NGFR and SORCS2. Mature BDNF has much lower affinity for the heterodimer formed by NGFR and SORCS2.
messages: Monomers and homodimers. Binds to NTRK2/TRKB.
messages: Secreted

89673:NIPBL
gene id: 89673:NIPBL
uniprot id: A0A7E6D9T8
uniprot id: A0A7E6DA57
uniprot id: A0A7E6DAV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC2/Nipped-B family.
messages: Nucleus

89673:KCNK13
gene id: 89673:KCNK13
uniprot id: A0A6J2L3T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

89673:ACTL8
gene id: 89673:ACTL8
uniprot id: A0A6J2LM56
names: Similarity
messages: Belongs to the actin family.

89673:HLF
gene id: 89673:HLF
uniprot id: A0A6J2MEF3
uniprot id: A0A6J2MHF1
uniprot id: A0A6J2MI96
uniprot id: A0A7E6EEZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

89673:PRPH2
gene id: 89673:PRPH2
uniprot id: A0A6J2LIN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRPH2/ROM1 family.
messages: Membrane

89673:PGAP1
gene id: 89673:PGAP1
uniprot id: A0A6J2LGI7
uniprot id: A0A7E6DJC6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI inositol-deacylase family.
messages: Endoplasmic reticulum membrane
messages: Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:TAFA3
gene id: 89673:TAFA3
uniprot id: A0A6J2KUF4
uniprot id: A0A7E6CV58
uniprot id: A0A7E6CV61
uniprot id: A0A7E6CVM2
uniprot id: A0A7E6CVX1
names: Similarity
messages: Belongs to the TAFA family.

89673:FUT1
gene id: 89673:FUT1
uniprot id: A0A6J2N2A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 11 family.
messages: Golgi stack membrane
messages: Membrane

89673:PDYN
gene id: 89673:PDYN
uniprot id: A0A6J2MMJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A(1-13) has a typical opioid activity, it is 700 times more potent than Leu-enkephalin.
messages: Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress.
messages: Leumorphin has a typical opioid activity and may have anti-apoptotic effect.
messages: Secreted

89673:COLGALT1
gene id: 89673:COLGALT1
uniprot id: A0A6J2M9Q1
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

89673:NCBP1
gene id: 89673:NCBP1
uniprot id: A0A6J2LGY8
uniprot id: A0A6J2LJB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NCBP1 family.
messages: Nucleus

89673:CLCN6
gene id: 89673:CLCN6
uniprot id: A0A6J2LPA5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:CARMIL2
gene id: 89673:CARMIL2
uniprot id: A0A6J2KRD0
uniprot id: A0A7E6CP40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CARMIL family.
messages: Cytoplasm

89673:ABCD1
gene id: 89673:ABCD1
uniprot id: A0A6J2MGA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.
messages: Membrane
messages: Peroxisome membrane

89673:LOC114513809
gene id: 89673:LOC114513809
uniprot id: A0A7E6D0A6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114512650
gene id: 89673:LOC114512650
uniprot id: A0A6J2NAZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

89673:TGFB1
gene id: 89673:TGFB1
uniprot id: A0A6J2N544
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Required to maintain the Transforming growth factor beta-1 (TGF-beta-1) chain in a latent state during storage in extracellular matrix. Associates non-covalently with TGF-beta-1 and regulates its activation via interaction with 'milieu molecules', such as LTBP1, LRRC32/GARP and LRRC33/NRROS, that control activation of TGF-beta-1. Interaction with LRRC33/NRROS regulates activation of TGF-beta-1 in macrophages and microglia. Interaction with LRRC32/GARP controls activation of TGF-beta-1 on the surface of activated regulatory T-cells (Tregs). Interaction with integrins (ITGAV:ITGB6 or ITGAV:ITGB8) results in distortion of the Latency-associated peptide chain and subsequent release of the active TGF-beta-1.
messages: Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.
messages: extracellular matrix

89673:AIG1
gene id: 89673:AIG1
uniprot id: A0A6J2LK04
uniprot id: A0A7E6DNG2
uniprot id: A0A7E6DNG4
uniprot id: A0A7E6DNI6
uniprot id: A0A7E6DNI9
uniprot id: A0A7E6DNY2
uniprot id: A0A7E6DNY7
uniprot id: A0A7E6DP54
uniprot id: A0A7E6DP58
uniprot id: A0A7E6DPF8
uniprot id: A0A7E6DPG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIG1 family.
messages: Membrane

89673:TK2
gene id: 89673:TK2
uniprot id: A0A6J2KQT9
names: Similarity
messages: Belongs to the DCK/DGK family.

89673:LIN28A
gene id: 89673:LIN28A
uniprot id: A0A6J2LPD7
names: Similarity
messages: Belongs to the lin-28 family.

89673:LOC114494393
gene id: 89673:LOC114494393
uniprot id: A0A6J2LHR8
uniprot id: A0A7E6DIN7
names: Similarity
messages: Belongs to the cytochrome P450 family.

89673:LOC114509216
gene id: 89673:LOC114509216
uniprot id: A0A6J2MSW4
uniprot id: A0A6J2MSW9
uniprot id: A0A6J2MSX4
uniprot id: A0A6J2MSY1
uniprot id: A0A6J2MUH7
uniprot id: A0A6J2MUI2
uniprot id: A0A6J2MUJ1
uniprot id: A0A6J2MUJ8
uniprot id: A0A6J2MUK2
uniprot id: A0A6J2MUK6
uniprot id: A0A6J2MZ46
uniprot id: A0A6J2MZ56
uniprot id: A0A6J2MZ61
uniprot id: A0A6J2MZL0
uniprot id: A0A6J2MZL8
uniprot id: A0A6J2MZL9
uniprot id: A0A6J2MZN1
uniprot id: A0A7E6CUS5
uniprot id: A0A7E6CV92
uniprot id: A0A7E6CVJ7
uniprot id: A0A7E6CXJ2
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

89673:CHST14
gene id: 89673:CHST14
uniprot id: A0A6J2L6S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

89673:LOC114500779
gene id: 89673:LOC114500779
uniprot id: A0A7E6D9E2
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

89673:POLR2E
gene id: 89673:POLR2E
uniprot id: A0A6J2M7N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. Seems to be the major component in this process.
messages: Nucleus

89673:LONP1
gene id: 89673:LONP1
uniprot id: A0A6J2MBB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand-specific manner. May regulate mitochondrial DNA replication and/or gene expression using site-specific, single-stranded DNA binding to target the degradation of regulatory proteins binding to adjacent sites in mitochondrial promoters.
messages: Belongs to the peptidase S16 family.
messages: Homohexamer. Organized in a ring with a central cavity. The ATP-binding and proteolytic domains (AP-domain) form a hexameric chamber, while the N-terminal domain is arranged as a trimer of dimers. DNA and RNA binding is stimulated by substrate and inhibited by ATP binding. Interacts with TWNK and mitochondrial DNA polymerase subunit POLG.
messages: Mitochondrion matrix

89673:TMEM97
gene id: 89673:TMEM97
uniprot id: A0A6J2M8D5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TMEM97/sigma-2 receptor family.
messages: Endoplasmic reticulum membrane
messages: Interacts with NPC1.
messages: Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.
messages: Membrane
messages: Nucleus membrane
messages: Rough endoplasmic reticulum membrane

89673:TH
gene id: 89673:TH
uniprot id: A0A6J2LZH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
messages: axon
messages: perinuclear region
messages: synaptic vesicle

89673:LOC114493903
gene id: 89673:LOC114493903
uniprot id: A0A7E6DKP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIIc family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits, encoded in the mitochondrial DNA, and 11 supernumerary subunits, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

89673:NDUFB6
gene id: 89673:NDUFB6
uniprot id: A0A6J2MZI2
uniprot id: A0A6J2MZK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB6 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

89673:PTPRU
gene id: 89673:PTPRU
uniprot id: A0A6J2LKS4
uniprot id: A0A6J2LNC8
uniprot id: A0A7E6DQT6
uniprot id: A0A7E6DRI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Membrane

89673:NCF2
gene id: 89673:NCF2
uniprot id: A0A7E6CW51
names: Similarity
messages: Belongs to the NCF2/NOXA1 family.

89673:PTGES2
gene id: 89673:PTGES2
uniprot id: A0A6J2LQI0
uniprot id: A0A7E6DGM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GST superfamily.
messages: Membrane

89673:ZBED6
gene id: 89673:ZBED6
uniprot id: A0A6J2N4Q8
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC118499667
gene id: 89673:LOC118499667
uniprot id: A0A7E6DEP1
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

89673:NTAQ1
gene id: 89673:NTAQ1
uniprot id: A0A6J2NJ03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NTAQ1 family.
messages: Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.
messages: Monomer.

89673:GALNT6
gene id: 89673:GALNT6
uniprot id: A0A6J2NFE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

89673:IMPDH2
gene id: 89673:IMPDH2
uniprot id: A0A6J2M406
uniprot id: A0A6J2M6T6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.
messages: Nucleus

89673:KRT40
gene id: 89673:KRT40
uniprot id: A0A6J2MBZ9
names: Similarity
messages: Belongs to the intermediate filament family.

89673:LOC114510937
gene id: 89673:LOC114510937
uniprot id: A0A7E6CQX8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

89673:ADIPOR2
gene id: 89673:ADIPOR2
uniprot id: A0A6J2NB14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

89673:LRP10
gene id: 89673:LRP10
uniprot id: A0A6J2L225
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114509930
gene id: 89673:LOC114509930
uniprot id: A0A6J2MXL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SSTR3
gene id: 89673:SSTR3
uniprot id: A0A6J2NA20
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:PPP1CB
gene id: 89673:PPP1CB
uniprot id: A0A6J2M2Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: nucleolus
messages: nucleoplasm

89673:LOC114488778
gene id: 89673:LOC114488778
uniprot id: A0A6J2KUN9
names: Similarity
messages: Belongs to the CD200R family.

89673:NT5E
gene id: 89673:NT5E
uniprot id: A0A6J2LLM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 5'-nucleotidase family.
messages: Membrane

89673:LOC114491018
gene id: 89673:LOC114491018
uniprot id: A0A7E6D028
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

89673:GUCY2C
gene id: 89673:GUCY2C
uniprot id: A0A6J2N8D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

89673:PSD4
gene id: 89673:PSD4
uniprot id: A0A7E6DZ57
uniprot id: A0A7E6DZK1
names: Subcellular Location Annotation
messages: Membrane
messages: ruffle membrane

89673:TNXB
gene id: 89673:TNXB
uniprot id: A0A7E6DKV1
uniprot id: A0A7E6DKV9
uniprot id: A0A7E6DL73
uniprot id: A0A7E6DL98
uniprot id: A0A7E6DLK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family.
messages: extracellular matrix

89673:DNAAF3
gene id: 89673:DNAAF3
uniprot id: A0A6J2N238
uniprot id: A0A6J2N7I7
uniprot id: A0A7E6CNR8
uniprot id: A0A7E6CNX2
uniprot id: A0A7E6CNZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNAAF3 family.
messages: Cytoplasm
messages: Dynein axonemal particle
messages: Required for the assembly of axonemal inner and outer dynein arms. Involved in preassembly of dyneins into complexes before their transport into cilia.

89673:CDH6
gene id: 89673:CDH6
uniprot id: A0A6J2MZZ1
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

89673:TMBIM6
gene id: 89673:TMBIM6
uniprot id: A0A6J2N7I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

89673:LOC114515353
gene id: 89673:LOC114515353
uniprot id: A0A6J2NFA6
uniprot id: A0A7E6ED30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCO1/2 family.
messages: Mitochondrion inner membrane

89673:SNURF
gene id: 89673:SNURF
uniprot id: A0A6J2KW78
names: Similarity
messages: Belongs to the SNURF family.

89673:STYXL2
gene id: 89673:STYXL2
uniprot id: A0A6J2N4S3
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

89673:ZNF326
gene id: 89673:ZNF326
uniprot id: A0A7E6DSZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AKAP95 family.
messages: Nucleus matrix

89673:HDAC4
gene id: 89673:HDAC4
uniprot id: A0A7E6DHG8
uniprot id: A0A7E6DHH4
uniprot id: A0A7E6DHL4
uniprot id: A0A7E6DHL9
uniprot id: A0A7E6DHN6
uniprot id: A0A7E6DHP1
uniprot id: A0A7E6DHR3
uniprot id: A0A7E6DHT3
uniprot id: A0A7E6DHT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

89673:LOC114489962
gene id: 89673:LOC114489962
uniprot id: A0A6J2KW63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

89673:PGLYRP4
gene id: 89673:PGLYRP4
uniprot id: A0A7E6CVQ4
uniprot id: A0A7E6CWD0
uniprot id: A0A7E6CYC5
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

89673:OSBPL7
gene id: 89673:OSBPL7
uniprot id: A0A6J2MDP4
uniprot id: A0A7E6EEH3
names: Similarity
messages: Belongs to the OSBP family.

89673:LOC114503719
gene id: 89673:LOC114503719
uniprot id: A0A7E6EHG0
names: Function
messages: May play an important role in spermatogenesis and/or testis development.

89673:PDE11A
gene id: 89673:PDE11A
uniprot id: A0A6J2LI44
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

89673:NCOA2
gene id: 89673:NCOA2
uniprot id: A0A6J2NH76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.
messages: Nucleus

89673:TOMM7
gene id: 89673:TOMM7
uniprot id: A0A6J2MN55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom7 family.
messages: Membrane
messages: Mitochondrion outer membrane

89673:GNG4
gene id: 89673:GNG4
uniprot id: A0A6J2NB36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

89673:GRIN2B
gene id: 89673:GRIN2B
uniprot id: A0A6J2NHF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

89673:OPRL1
gene id: 89673:OPRL1
uniprot id: A0A6J2MJX3
uniprot id: A0A6J2MR19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin.
messages: Membrane
messages: Vesicle

89673:LOC114507866
gene id: 89673:LOC114507866
uniprot id: A0A6J2MQB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114498455
gene id: 89673:LOC114498455
uniprot id: A0A6J2LWF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:KCNAB1
gene id: 89673:KCNAB1
uniprot id: A0A6J2L417
uniprot id: A0A6J2L5I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

89673:S100B
gene id: 89673:S100B
uniprot id: A0A6J2L0V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the S-100 family.
messages: Cytoplasm
messages: Nucleus
messages: Secreted

89673:ABCD2
gene id: 89673:ABCD2
uniprot id: A0A6J2NBU6
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114497487
gene id: 89673:LOC114497487
uniprot id: A0A6J2LQ05
names: Subcellular Location Annotation
messages: Membrane

89673:MELK
gene id: 89673:MELK
uniprot id: A0A7E6DFK6
uniprot id: A0A7E6DFP5
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

89673:ACTRT1
gene id: 89673:ACTRT1
uniprot id: A0A7E6CZ14
names: Similarity
messages: Belongs to the actin family.

89673:ALG5
gene id: 89673:ALG5
uniprot id: A0A6J2MXU7
uniprot id: A0A7E6CJH5
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

89673:UCHL3
gene id: 89673:UCHL3
uniprot id: A0A6J2MWC1
uniprot id: A0A7E6CJV5
names: Similarity
messages: Belongs to the peptidase C12 family.

89673:LRP6
gene id: 89673:LRP6
uniprot id: A0A6J2NAQ2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDLR family.
messages: Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalosomes.
messages: Homodimer; disulfide-linked. Forms phosphorylated oligomer aggregates on Wnt-signaling.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:SP4
gene id: 89673:SP4
uniprot id: A0A6J2MRB1
uniprot id: A0A6J2MVN6
names: Subcellular Location Annotation
messages: Nucleus

89673:HPGD
gene id: 89673:HPGD
uniprot id: A0A6J2MHJ2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

89673:RSPH3
gene id: 89673:RSPH3
uniprot id: A0A6J2LJY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the flagellar radial spoke RSP3 family.
messages: flagellum axoneme

89673:LOC114513461
gene id: 89673:LOC114513461
uniprot id: A0A6J2N9S6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

89673:TP73
gene id: 89673:TP73
uniprot id: A0A6J2LLU0
uniprot id: A0A6J2LP53
uniprot id: A0A7E6DQB1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Found in a complex with p53/TP53 and CABLES1.
messages: Mitochondrion matrix
messages: Nucleus
messages: PML body
messages: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
messages: centrosome

89673:IZUMO4
gene id: 89673:IZUMO4
uniprot id: A0A7E6EH40
names: Similarity
messages: Belongs to the Izumo family.

89673:LOC114493251
gene id: 89673:LOC114493251
uniprot id: A0A6J2LCS1
names: Subcellular Location Annotation
messages: extracellular matrix

89673:SYT2
gene id: 89673:SYT2
uniprot id: A0A6J2N9I9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: synaptic vesicle membrane

89673:GPR17
gene id: 89673:GPR17
uniprot id: A0A6J2LGY3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:KCNQ4
gene id: 89673:KCNQ4
uniprot id: A0A6J2LL50
uniprot id: A0A6J2LNS7
uniprot id: A0A7E6DS02
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:CD40LG
gene id: 89673:CD40LG
uniprot id: A0A6J2MLJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a ligand for integrins, specifically ITGA5:ITGB1 and ITGAV:ITGB3; both integrins and the CD40 receptor are required for activation of CD40-CD40LG signaling, which have cell-type dependent effects, such as B-cell activation, NF-kappa-B signaling and anti-apoptotic signaling.
messages: Belongs to the tumor necrosis factor family.
messages: Cell surface
messages: Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
messages: Homotrimer.

89673:MND1
gene id: 89673:MND1
uniprot id: A0A6J2MHS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MND1 family.
messages: Nucleus
messages: Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis.

89673:LOC114491866
gene id: 89673:LOC114491866
uniprot id: A0A6J2L2R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-casein family.
messages: Important role in determination of the surface properties of the casein micelles.
messages: Secreted

89673:SERINC1
gene id: 89673:SERINC1
uniprot id: A0A6J2LGM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

89673:CACNB1
gene id: 89673:CACNB1
uniprot id: A0A6J2M9A3
uniprot id: A0A6J2MBF1
uniprot id: A0A7E6EDT7
uniprot id: A0A7E6EFE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: Membrane
messages: sarcolemma

89673:GNB4
gene id: 89673:GNB4
uniprot id: A0A6J2L0W8
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

89673:LOC114491563
gene id: 89673:LOC114491563
uniprot id: A0A7E6D7L9
uniprot id: A0A7E6D7T5
uniprot id: A0A7E6D7U1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

89673:LAPTM4B
gene id: 89673:LAPTM4B
uniprot id: A0A6J2NBB3
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

89673:PAQR4
gene id: 89673:PAQR4
uniprot id: A0A6J2LFR0
uniprot id: A0A6J2LI24
uniprot id: A0A6J2LKK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

89673:WAS
gene id: 89673:WAS
uniprot id: A0A6J2MGH3
names: Subcellular Location Annotation
messages: Nucleus

89673:ERO1A
gene id: 89673:ERO1A
uniprot id: A0A7E6CG72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane

89673:HMX1
gene id: 89673:HMX1
uniprot id: A0A6J2KWH6
names: Subcellular Location Annotation
messages: Nucleus

89673:B9D1
gene id: 89673:B9D1
uniprot id: A0A6J2NC91
uniprot id: A0A6J2NDV4
uniprot id: A0A7E6EAY4
uniprot id: A0A7E6EBR2
uniprot id: A0A7E6ECI0
uniprot id: A0A7E6ECV1
names: Subcellular Location Annotation
messages: cilium basal body

89673:PPARGC1A
gene id: 89673:PPARGC1A
uniprot id: A0A6J2L166
uniprot id: A0A6J2L1X7
uniprot id: A0A6J2L5H5
uniprot id: A0A7E6D7N8
uniprot id: A0A7E6D7P2
names: Subcellular Location Annotation
messages: PML body

89673:HSPB9
gene id: 89673:HSPB9
uniprot id: A0A6J2MEJ0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

89673:SKA2
gene id: 89673:SKA2
uniprot id: A0A7E6EDY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKA2 family.
messages: spindle

89673:TAP2
gene id: 89673:TAP2
uniprot id: A0A6J2LEJ9
uniprot id: A0A6J2LJ76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCB family. MHC peptide exporter (TC 3.A.1.209) subfamily.
messages: Membrane

89673:THEMIS
gene id: 89673:THEMIS
uniprot id: A0A7E6DN38
uniprot id: A0A7E6DNS0
names: Similarity
messages: Belongs to the themis family.

89673:KDM6B
gene id: 89673:KDM6B
uniprot id: A0A6J2NJQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTX family.
messages: Nucleus

89673:PLA2G6
gene id: 89673:PLA2G6
uniprot id: A0A7E6D8F4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:POLR1A
gene id: 89673:POLR1A
uniprot id: A0A6J2LYU4
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

89673:NCOR1
gene id: 89673:NCOR1
uniprot id: A0A7E6EBW6
names: Similarity
messages: Belongs to the N-CoR nuclear receptor corepressors family.

89673:NACC1
gene id: 89673:NACC1
uniprot id: A0A6J2M9K9
names: Subcellular Location Annotation
messages: Nucleus

89673:CDH20
gene id: 89673:CDH20
uniprot id: A0A6J2MQL9
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

89673:GFRA2
gene id: 89673:GFRA2
uniprot id: A0A6J2MEN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDNFR family.
messages: Cell membrane
messages: Membrane
messages: Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.

89673:PAX4
gene id: 89673:PAX4
uniprot id: A0A6J2MSU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

89673:YPEL4
gene id: 89673:YPEL4
uniprot id: A0A6J2M1E0
names: Similarity
messages: Belongs to the yippee family.

89673:SKAP1
gene id: 89673:SKAP1
uniprot id: A0A7E6EEA0
names: Similarity
messages: Belongs to the SKAP family.

89673:CFAP299
gene id: 89673:CFAP299
uniprot id: A0A7E6DHA0
uniprot id: A0A7E6DHJ3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in spermatogenesis.
messages: Nucleus

89673:TUBB4A
gene id: 89673:TUBB4A
uniprot id: A0A6J2M8Q6
uniprot id: A0A7E6E9X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

89673:FADS2
gene id: 89673:FADS2
uniprot id: A0A6J2LZM4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

89673:BLMH
gene id: 89673:BLMH
uniprot id: A0A6J2MA71
uniprot id: A0A7E6EE01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Cytoplasm

89673:BNIP3
gene id: 89673:BNIP3
uniprot id: A0A6J2LRC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

89673:MEX3D
gene id: 89673:MEX3D
uniprot id: A0A7E6E8R0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

89673:RNMT
gene id: 89673:RNMT
uniprot id: A0A6J2MKP2
uniprot id: A0A7E6CE27
uniprot id: A0A7E6CET6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
messages: In the N-terminal section; belongs to the dsDNA virus mRNA guanylyltransferase family.
messages: Nucleus

89673:RAB5IF
gene id: 89673:RAB5IF
uniprot id: A0A6J2MP95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:LOC114498075
gene id: 89673:LOC114498075
uniprot id: A0A6J2LVH3
names: Subcellular Location Annotation
messages: Nucleus

89673:FAM168A
gene id: 89673:FAM168A
uniprot id: A0A6J2LVM5
uniprot id: A0A6J2M0L4
uniprot id: A0A6J2M136
uniprot id: A0A7E6DZU6
names: Similarity
messages: Belongs to the FAM168 family.

89673:LOC114493439
gene id: 89673:LOC114493439
uniprot id: A0A6J2LDF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase VIIb family.
messages: Membrane
messages: Mitochondrion inner membrane

89673:DCTD
gene id: 89673:DCTD
uniprot id: A0A6J2MSI3
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

89673:BORCS5
gene id: 89673:BORCS5
uniprot id: A0A6J2NDT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS5 family.
messages: Lysosome membrane
messages: Membrane

89673:KAT7
gene id: 89673:KAT7
uniprot id: A0A6J2MBI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

89673:FGG
gene id: 89673:FGG
uniprot id: A0A6J2M8G0
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

89673:KCNK1
gene id: 89673:KCNK1
uniprot id: A0A6J2N5M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: Recycling endosome
messages: Synaptic cell membrane
messages: Vesicle
messages: dendrite

89673:CSMD3
gene id: 89673:CSMD3
uniprot id: A0A6J2NC60
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:CCL26
gene id: 89673:CCL26
uniprot id: A0A6J2LZ74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

89673:NCDN
gene id: 89673:NCDN
uniprot id: A0A6J2LIE7
uniprot id: A0A6J2LIF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurochondrin family.
messages: Postsynapse

89673:PKP1
gene id: 89673:PKP1
uniprot id: A0A6J2N5F0
names: Similarity
messages: Belongs to the beta-catenin family.

89673:CDH7
gene id: 89673:CDH7
uniprot id: A0A6J2MKV4
uniprot id: A0A7E6CGX0
uniprot id: A0A7E6CIL2
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

89673:LOC114489982
gene id: 89673:LOC114489982
uniprot id: A0A7E6DLA8
uniprot id: A0A7E6DLR8
names: Similarity
messages: Belongs to the MHC class I family.

89673:FRAT2
gene id: 89673:FRAT2
uniprot id: A0A7E6DVR6
names: Similarity
messages: Belongs to the GSK-3-binding protein family.

89673:UBE2S
gene id: 89673:UBE2S
uniprot id: A0A6J2N5P8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

89673:RBM17
gene id: 89673:RBM17
uniprot id: A0A6J2L7M5
uniprot id: A0A7E6DN25
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the spliceosome.
messages: Nucleus
messages: Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites.

89673:ERG28
gene id: 89673:ERG28
uniprot id: A0A6J2L658
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG28 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:BRCC3
gene id: 89673:BRCC3
uniprot id: A0A6J2MKS7
uniprot id: A0A7E6D010
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M67A family. BRCC36 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Component of the ARISC complex, at least composed of UIMC1/RAP80, ABRAXAS1, BRCC3/BRCC36, BABAM2 and BABAM1/NBA1. Component of the BRCA1-A complex, at least composed of BRCA1, BARD1, UIMC1/RAP80, ABRAXAS1, BRCC3/BRCC36, BABAM2 and BABAM1/NBA1. In the BRCA1-A complex, interacts directly with ABRAXAS1 and BABAM2. Component of the BRISC complex, at least composed of ABRAXAS2, BRCC3/BRCC36, BABAM2 and BABAM1/NBA1. Identified in a complex with SHMT2 and the other subunits of the BRISC complex. In the BRISC complex, interacts directly with ABRAXAS2. Identified in a complex with ABRAXAS2 and NUMA1. The BRISC complex interacts with the CSN complex. Component of the BRCA1/BRCA2 containing complex (BRCC), which also contains BRCA1, BRCA2, BARD1, BABAM2 and RAD51. BRCC is a ubiquitin E3 ligase complex that enhances cellular survival following DNA damage. Interacts with BRCA1. Binds polyubiquitin. Interacts with PWWP2B. Interacts with HDAC1; this interaction is enhanced in the presence of PWWP2B.
messages: Cytoplasm
messages: Metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the brca1-bard1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). Catalytic subunit of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin in various substrates. Mediates the specific 'Lys-63'-specific deubiquitination associated with the COP9 signalosome complex (CSN), via the interaction of the BRISC complex with the CSN complex. The BRISC complex is required for normal mitotic spindle assembly and microtubule attachment to kinetochores via its role in deubiquitinating NUMA1.
messages: Nucleus
messages: spindle pole

89673:RPUSD2
gene id: 89673:RPUSD2
uniprot id: A0A7E6E8G4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

89673:SEMA3A
gene id: 89673:SEMA3A
uniprot id: A0A6J2MP10
uniprot id: A0A7E6CIB5
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:CAMK1
gene id: 89673:CAMK1
uniprot id: A0A6J2M6Q8
uniprot id: A0A7E6E579
uniprot id: A0A7E6E6R5
uniprot id: A0A7E6E6W2
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:LOC114490184
gene id: 89673:LOC114490184
uniprot id: A0A6J2KWX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ELL
gene id: 89673:ELL
uniprot id: A0A7E6EC40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

89673:SLC45A1
gene id: 89673:SLC45A1
uniprot id: A0A6J2LQC8
names: Subcellular Location Annotation
messages: Membrane

89673:DHTKD1
gene id: 89673:DHTKD1
uniprot id: A0A6J2LCE8
uniprot id: A0A7E6DMN8
uniprot id: A0A7E6DMP5
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

89673:C5H10orf53
gene id: 89673:C5H10orf53
uniprot id: A0A6J2LH54
names: Similarity
messages: Belongs to the UPF0728 family.

89673:ABHD1
gene id: 89673:ABHD1
uniprot id: A0A6J2LWP2
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

89673:POLR2G
gene id: 89673:POLR2G
uniprot id: A0A6J2M0B9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits. RPB4 and RPB7 form a subcomplex that protrudes from the 10-subunit Pol II core complex.
messages: DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

89673:NUP58
gene id: 89673:NUP58
uniprot id: A0A6J2L1V2
uniprot id: A0A6J2L3P2
names: Subcellular Location Annotation
messages: nuclear pore complex

89673:PRPF18
gene id: 89673:PRPF18
uniprot id: A0A6J2L4T0
uniprot id: A0A6J2L6Y3
uniprot id: A0A7E6DN45
uniprot id: A0A7E6DN50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP18 family.
messages: Nucleus speckle

89673:TRIP12
gene id: 89673:TRIP12
uniprot id: A0A6J2L980
uniprot id: A0A6J2L985
uniprot id: A0A6J2L988
uniprot id: A0A6J2L9Q4
uniprot id: A0A6J2L9R1
uniprot id: A0A6J2LB22
uniprot id: A0A6J2LDS7
uniprot id: A0A7E6DHT2
uniprot id: A0A7E6DHX3
uniprot id: A0A7E6DHX9
uniprot id: A0A7E6DHZ7
uniprot id: A0A7E6DI02
uniprot id: A0A7E6DI17
uniprot id: A0A7E6DI22
uniprot id: A0A7E6DI45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPL family. K-HECT subfamily.
messages: E3 ubiquitin-protein ligase involved in ubiquitin fusion degradation (UFD) pathway and regulation of DNA repair. Part of the ubiquitin fusion degradation (UFD) pathway, a process that mediates ubiquitination of protein at their N-terminus, regardless of the presence of lysine residues in target proteins.
messages: nucleoplasm

89673:ST6GALNAC6
gene id: 89673:ST6GALNAC6
uniprot id: A0A6J2LUR1
uniprot id: A0A7E6DGI1
uniprot id: A0A7E6DGL5
uniprot id: A0A7E6DGL9
uniprot id: A0A7E6DGQ9
uniprot id: A0A7E6DGS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

89673:MPDZ
gene id: 89673:MPDZ
uniprot id: A0A6J2LGL3
uniprot id: A0A7E6DEM1
uniprot id: A0A7E6DEN6
uniprot id: A0A7E6DER0
uniprot id: A0A7E6DER3
names: Subcellular Location Annotation
messages: Cell membrane
messages: tight junction

89673:LOC114508802
gene id: 89673:LOC114508802
uniprot id: A0A7E6CKW5
names: Similarity
messages: Belongs to the SKP1 family.

89673:KPNB1
gene id: 89673:KPNB1
uniprot id: A0A6J2M818
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the importin beta family. Importin beta-1 subfamily.
messages: Cytoplasm

89673:PSENEN
gene id: 89673:PSENEN
uniprot id: A0A6J2N0Z8
uniprot id: A0A7E6CQU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEN-2 family.
messages: Golgi stack membrane
messages: Membrane

89673:SH3PXD2A
gene id: 89673:SH3PXD2A
uniprot id: A0A6J2LIV6
uniprot id: A0A6J2LL68
uniprot id: A0A6J2LNV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3PXD2 family.
messages: Cytoplasm

89673:LOC114514975
gene id: 89673:LOC114514975
uniprot id: A0A6J2NII5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:PPP6C
gene id: 89673:PPP6C
uniprot id: A0A6J2N8U6
uniprot id: A0A7E6DGG4
uniprot id: A0A7E6DGK5
uniprot id: A0A7E6DGM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family.
messages: Cytoplasm

89673:MAT2B
gene id: 89673:MAT2B
uniprot id: A0A6J2MY46
uniprot id: A0A6J2N3G7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family. MAT2B subfamily.
messages: Heterotrimer; composed of a catalytic MAT2A homodimer that binds one regulatory MAT2B chain. Heterohexamer; composed of a central, catalytic MAT2A homotetramer flanked on either side by a regulatory MAT2B chain. NADP binding increases the affinity for MAT2A.
messages: Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.

89673:EDIL3
gene id: 89673:EDIL3
uniprot id: A0A6J2MN86
uniprot id: A0A6J2MUV4
uniprot id: A0A7E6DBT8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:ACADM
gene id: 89673:ACADM
uniprot id: A0A6J2LNH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Mitochondrion matrix

89673:PDPR
gene id: 89673:PDPR
uniprot id: A0A6J2KQ38
uniprot id: A0A7E6CME3
uniprot id: A0A7E6CMH1
uniprot id: A0A7E6CPQ6
names: Similarity
messages: Belongs to the GcvT family.

89673:MRPS11
gene id: 89673:MRPS11
uniprot id: A0A6J2KS09
uniprot id: A0A7E6CPY7
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

89673:FAM193B
gene id: 89673:FAM193B
uniprot id: A0A6J2MWM6
uniprot id: A0A7E6CTR0
uniprot id: A0A7E6CTS2
uniprot id: A0A7E6CTT2
uniprot id: A0A7E6CU91
uniprot id: A0A7E6CU95
uniprot id: A0A7E6CUH6
uniprot id: A0A7E6CWK5
names: Similarity
messages: Belongs to the FAM193 family.

89673:C1H4orf48
gene id: 89673:C1H4orf48
uniprot id: A0A6J2L036
names: Subcellular Location Annotation
messages: Secreted

89673:ROGDI
gene id: 89673:ROGDI
uniprot id: A0A6J2LL43
uniprot id: A0A7E6DBT3
uniprot id: A0A7E6DDK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rogdi family.
messages: Presynapse
messages: Vesicle
messages: synaptic vesicle

89673:PLXNA4
gene id: 89673:PLXNA4
uniprot id: A0A6J2MP01
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:LOC114498762
gene id: 89673:LOC114498762
uniprot id: A0A7E6DYR0
uniprot id: A0A7E6DZM1
names: Subcellular Location Annotation
messages: Nucleus

89673:NLRP5
gene id: 89673:NLRP5
uniprot id: A0A7E6CRC8
names: Similarity
messages: Belongs to the NLRP family.

89673:TIMM10
gene id: 89673:TIMM10
uniprot id: A0A6J2M237
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

89673:HOXC9
gene id: 89673:HOXC9
uniprot id: A0A6J2NAL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

89673:SLC44A4
gene id: 89673:SLC44A4
uniprot id: A0A7E6DKV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

89673:SLC17A4
gene id: 89673:SLC17A4
uniprot id: A0A6J2KVJ8
names: Subcellular Location Annotation
messages: Membrane

89673:YWHAG
gene id: 89673:YWHAG
uniprot id: A0A6J2L5C0
names: Similarity
messages: Belongs to the 14-3-3 family.

89673:LOC114507443
gene id: 89673:LOC114507443
uniprot id: A0A6J2MLN6
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

89673:TRAK1
gene id: 89673:TRAK1
uniprot id: A0A6J2M6L4
uniprot id: A0A6J2M6L9
uniprot id: A0A6J2M771
uniprot id: A0A7E6E4S7
uniprot id: A0A7E6E4X0
uniprot id: A0A7E6E5Q2
uniprot id: A0A7E6E5W0
uniprot id: A0A7E6E5W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the milton family.
messages: Early endosome
messages: Mitochondrion

89673:LOC114500255
gene id: 89673:LOC114500255
uniprot id: A0A6J2LZD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TIMM8A
gene id: 89673:TIMM8A
uniprot id: A0A6J2MHV0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

89673:FAM163A
gene id: 89673:FAM163A
uniprot id: A0A6J2N4J2
uniprot id: A0A7E6CYB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

89673:RPAP2
gene id: 89673:RPAP2
uniprot id: A0A7E6DTQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the RNA polymerase II complex. Interacts with transcribing RNA polymerase II phosphorylated on 'Ser-7' on CTD.
messages: Belongs to the RPAP2 family.
messages: Nucleus
messages: Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated 'Ser-7' of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of 'Ser-5' of the CTD, thereby promoting transcription of snRNA genes.

89673:LOC114494380
gene id: 89673:LOC114494380
uniprot id: A0A7E6DIC2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

89673:ZFYVE27
gene id: 89673:ZFYVE27
uniprot id: A0A6J2LLQ5
uniprot id: A0A6J2LN21
uniprot id: A0A6J2LS43
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: growth cone membrane

89673:FOXO4
gene id: 89673:FOXO4
uniprot id: A0A7E6D262
names: Subcellular Location Annotation
messages: Nucleus

89673:MACIR
gene id: 89673:MACIR
uniprot id: A0A6J2LM93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UNC119-binding protein family.
messages: Cytoplasm
messages: cilium

89673:FAM53A
gene id: 89673:FAM53A
uniprot id: A0A7E6D446
names: Similarity
messages: Belongs to the FAM53 family.

89673:MRPL27
gene id: 89673:MRPL27
uniprot id: A0A6J2MBX7
uniprot id: A0A7E6EEA3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

89673:MED31
gene id: 89673:MED31
uniprot id: A0A6J2NJ44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 31 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

89673:RTN3
gene id: 89673:RTN3
uniprot id: A0A6J2LUU2
uniprot id: A0A6J2M0C3
uniprot id: A0A6J2M0C8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:B3GALT5
gene id: 89673:B3GALT5
uniprot id: A0A6J2L2E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

89673:FAM219A
gene id: 89673:FAM219A
uniprot id: A0A6J2M3W5
uniprot id: A0A6J2M5L9
uniprot id: A0A6J2M624
uniprot id: A0A6J2M655
uniprot id: A0A7E6DFD5
uniprot id: A0A7E6DFF4
uniprot id: A0A7E6DFH2
uniprot id: A0A7E6DFH9
names: Similarity
messages: Belongs to the FAM219 family.

89673:JUN
gene id: 89673:JUN
uniprot id: A0A6J2LL01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

89673:CDCA2
gene id: 89673:CDCA2
uniprot id: A0A6J2M8B6
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114489466
gene id: 89673:LOC114489466
uniprot id: A0A7E6CZW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

89673:LOC114498915
gene id: 89673:LOC114498915
uniprot id: A0A6J2LUM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114507400
gene id: 89673:LOC114507400
uniprot id: A0A6J2MNI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CD8A
gene id: 89673:CD8A
uniprot id: A0A6J2LZD4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:LOC114504168
gene id: 89673:LOC114504168
uniprot id: A0A6J2MHA6
names: Caution
names: Similarity
messages: Belongs to the HHIP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114497203
gene id: 89673:LOC114497203
uniprot id: A0A6J2LLH5
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

89673:EPHA1
gene id: 89673:EPHA1
uniprot id: A0A6J2MV40
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114500786
gene id: 89673:LOC114500786
uniprot id: A0A6J2M261
names: Similarity
messages: Belongs to the calcitonin family.

89673:SLC25A22
gene id: 89673:SLC25A22
uniprot id: A0A6J2LW62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

89673:FAM207A
gene id: 89673:FAM207A
uniprot id: A0A6J2L339
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLX9 family.
messages: nucleolus

89673:RAB39A
gene id: 89673:RAB39A
uniprot id: A0A6J2LWP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

89673:ARHGDIG
gene id: 89673:ARHGDIG
uniprot id: A0A6J2MD01
uniprot id: A0A7E6DCL8
uniprot id: A0A7E6DDP6
names: Similarity
messages: Belongs to the Rho GDI family.

89673:MMP13
gene id: 89673:MMP13
uniprot id: A0A6J2M2N5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

89673:TLE5
gene id: 89673:TLE5
uniprot id: A0A6J2MIR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

89673:TRAPPC3
gene id: 89673:TRAPPC3
uniprot id: A0A6J2LJ34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Homodimer.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: cis-Golgi network

89673:NUMB
gene id: 89673:NUMB
uniprot id: A0A6J2L260
uniprot id: A0A6J2L5S7
uniprot id: A0A7E6CLE0
names: Function
messages: Plays a role in the process of neurogenesis.

89673:SLC25A29
gene id: 89673:SLC25A29
uniprot id: A0A6J2LAZ6
uniprot id: A0A7E6CSW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

89673:ADAMTS2
gene id: 89673:ADAMTS2
uniprot id: A0A6J2NEW3
uniprot id: A0A7E6ECJ6
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

89673:GAPDHS
gene id: 89673:GAPDHS
uniprot id: A0A6J2N7X6
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

89673:ABCB1
gene id: 89673:ABCB1
uniprot id: A0A6J2MQW9
names: Subcellular Location Annotation
messages: Membrane

89673:RNF182
gene id: 89673:RNF182
uniprot id: A0A6J2LKT1
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with ATP6V0C.
messages: Membrane

89673:ADAM21
gene id: 89673:ADAM21
uniprot id: A0A6J2L7X0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:COPS7B
gene id: 89673:COPS7B
uniprot id: A0A6J2LHQ0
uniprot id: A0A7E6DHR0
uniprot id: A0A7E6DHU9
uniprot id: A0A7E6DHV3
uniprot id: A0A7E6DHY8
uniprot id: A0A7E6DHZ3
uniprot id: A0A7E6DI20
uniprot id: A0A7E6DI24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
messages: Cytoplasm
messages: Nucleus

89673:RHCG
gene id: 89673:RHCG
uniprot id: A0A6J2KXZ2
uniprot id: A0A7E6CPY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

89673:LGI4
gene id: 89673:LGI4
uniprot id: A0A6J2N194
uniprot id: A0A7E6CLE2
uniprot id: A0A7E6CLG4
names: Subcellular Location Annotation
messages: Secreted

89673:CUL4B
gene id: 89673:CUL4B
uniprot id: A0A6J2MLE8
uniprot id: A0A6J2MM79
uniprot id: A0A7E6D094
uniprot id: A0A7E6D099
uniprot id: A0A7E6D0A4
uniprot id: A0A7E6D0H1
uniprot id: A0A7E6D0H6
uniprot id: A0A7E6D166
uniprot id: A0A7E6D331
uniprot id: A0A7E6D336
names: Similarity
messages: Belongs to the cullin family.

89673:LOC114509079
gene id: 89673:LOC114509079
uniprot id: A0A6J2MS04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114500166
gene id: 89673:LOC114500166
uniprot id: A0A6J2LZW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SIAH2
gene id: 89673:SIAH2
uniprot id: A0A6J2L1G0
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

89673:PFDN4
gene id: 89673:PFDN4
uniprot id: A0A6J2MLP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

89673:OGFRL1
gene id: 89673:OGFRL1
uniprot id: A0A6J2LH19
uniprot id: A0A7E6DMY7
names: Similarity
messages: Belongs to the opioid growth factor receptor family.

89673:MAP3K5
gene id: 89673:MAP3K5
uniprot id: A0A6J2LB47
uniprot id: A0A7E6DNG7
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

89673:SLC5A5
gene id: 89673:SLC5A5
uniprot id: A0A7E6E9X4
uniprot id: A0A7E6EAX1
uniprot id: A0A7E6EBZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

89673:LOC114497753
gene id: 89673:LOC114497753
uniprot id: A0A6J2LU73
uniprot id: A0A7E6DR04
names: Subcellular Location Annotation
messages: Membrane

89673:SOX14
gene id: 89673:SOX14
uniprot id: A0A6J2M5I7
names: Subcellular Location Annotation
messages: Nucleus

89673:ATP6V0D1
gene id: 89673:ATP6V0D1
uniprot id: A0A6J2KWD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

89673:KATNB1
gene id: 89673:KATNB1
uniprot id: A0A6J2KT43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat KATNB1 family.
messages: Cytoplasm
messages: Interacts with KATNA1. This interaction enhances the microtubule binding and severing activity of KATNA1 and also targets this activity to the centrosome. This interaction is weakly competed by KATNBL1 which has a lower affinity for it. Interacts with ASPM; the katanin complex formation KATNA1:KATNB1 is required for the association of ASPM. Interacts with dynein, microtubules, NDEL1 and PAFAH1B1. Interacts with KATNAL1; this interaction is weakly competed by KATNBL1 which has a lower affinity for it. Interacts with CAMSAP2 and CAMSAP3; leading to regulate the length of CAMSAP-decorated microtubule stretches.
messages: Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.
messages: centrosome
messages: cytoskeleton
messages: spindle
messages: spindle pole

89673:SPX
gene id: 89673:SPX
uniprot id: A0A7E6DA73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spexin family.
messages: Secreted

89673:CD40
gene id: 89673:CD40
uniprot id: A0A6J2MJZ1
uniprot id: A0A7E6CFQ2
uniprot id: A0A7E6CFU9
uniprot id: A0A7E6CG87
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:SYCE1L
gene id: 89673:SYCE1L
uniprot id: A0A7E6CPX5
names: Similarity
messages: Belongs to the SYCE family.

89673:HYOU1
gene id: 89673:HYOU1
uniprot id: A0A6J2LXE4
names: Similarity
messages: Belongs to the heat shock protein 70 family.

89673:LOC114512668
gene id: 89673:LOC114512668
uniprot id: A0A6J2N6I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

89673:LOC114511480
gene id: 89673:LOC114511480
uniprot id: A0A6J2N2A6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 11 family.
messages: Golgi stack membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:OSGEPL1
gene id: 89673:OSGEPL1
uniprot id: A0A6J2LGL1
uniprot id: A0A7E6DJ34
uniprot id: A0A7E6DJA7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Mitochondrion
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.

89673:PDP1
gene id: 89673:PDP1
uniprot id: A0A6J2NAD2
uniprot id: A0A6J2NC93
names: Similarity
messages: Belongs to the PP2C family.

89673:IL10
gene id: 89673:IL10
uniprot id: A0A6J2N9K1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-10 family.
messages: Homodimer. Interacts with IL10RA and IL10RB.
messages: Immune regulatory cytokine.
messages: Secreted

89673:NEU2
gene id: 89673:NEU2
uniprot id: A0A6J2LHH6
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

89673:LYPLAL1
gene id: 89673:LYPLAL1
uniprot id: A0A6J2N3U6
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

89673:KCNN3
gene id: 89673:KCNN3
uniprot id: A0A6J2KYA8
uniprot id: A0A7E6CX78
uniprot id: A0A7E6CXR0
uniprot id: A0A7E6CY43
uniprot id: A0A7E6CZX4
names: Subcellular Location Annotation
messages: Membrane

89673:FEZ2
gene id: 89673:FEZ2
uniprot id: A0A6J2LV00
uniprot id: A0A6J2LW36
names: Similarity
messages: Belongs to the zygin family.

89673:SLC30A9
gene id: 89673:SLC30A9
uniprot id: A0A6J2L570
uniprot id: A0A6J2L5V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Endoplasmic reticulum
messages: Membrane
messages: Mitochondrion membrane
messages: Nucleus

89673:ACADVL
gene id: 89673:ACADVL
uniprot id: A0A6J2NDX5
uniprot id: A0A6J2NIL0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

89673:FIGNL1
gene id: 89673:FIGNL1
uniprot id: A0A6J2MQS6
names: Similarity
messages: Belongs to the AAA ATPase family.

89673:ASIC2
gene id: 89673:ASIC2
uniprot id: A0A6J2MB66
uniprot id: A0A6J2MDD7
names: Subcellular Location Annotation
messages: Membrane

89673:FCGRT
gene id: 89673:FCGRT
uniprot id: A0A6J2MZC3
uniprot id: A0A7E6CNC3
names: Similarity
messages: Belongs to the MHC class I family.

89673:TMEM198
gene id: 89673:TMEM198
uniprot id: A0A6J2LHN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM198 family.
messages: Membrane

89673:CHGA
gene id: 89673:CHGA
uniprot id: A0A7E6CR41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

89673:TPI1
gene id: 89673:TPI1
uniprot id: A0A6J2NF89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.
messages: It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
messages: Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.

89673:LOC114492164
gene id: 89673:LOC114492164
uniprot id: A0A6J2L981
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

89673:SCUBE3
gene id: 89673:SCUBE3
uniprot id: A0A6J2LD53
uniprot id: A0A6J2LE38
uniprot id: A0A7E6DL70
uniprot id: A0A7E6DLK2
uniprot id: A0A7E6DLX8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:RBM47
gene id: 89673:RBM47
uniprot id: A0A7E6D9F2
uniprot id: A0A7E6D9K5
uniprot id: A0A7E6DCC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM RBM47 family.
messages: Cytoplasm
messages: Nucleus

89673:NDUFA5
gene id: 89673:NDUFA5
uniprot id: A0A6J2MP56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA5 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

89673:TRAPPC11
gene id: 89673:TRAPPC11
uniprot id: A0A6J2MWV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPPC11 family.
messages: Involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage.
messages: cis-Golgi network

89673:LOC114504798
gene id: 89673:LOC114504798
uniprot id: A0A6J2MJX4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

89673:MOCOS
gene id: 89673:MOCOS
uniprot id: A0A6J2MKN1
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.
messages: Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.

89673:BAP1
gene id: 89673:BAP1
uniprot id: A0A6J2M468
uniprot id: A0A7E6E5V9
names: Similarity
messages: Belongs to the peptidase C12 family.

89673:LOC114505154
gene id: 89673:LOC114505154
uniprot id: A0A7E6CZV8
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

89673:ACAT2
gene id: 89673:ACAT2
uniprot id: A0A6J2LCT4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

89673:ADAM22
gene id: 89673:ADAM22
uniprot id: A0A6J2MN25
uniprot id: A0A6J2MN31
uniprot id: A0A6J2MQ07
uniprot id: A0A6J2MQ10
uniprot id: A0A6J2MUC9
uniprot id: A0A6J2MUD5
uniprot id: A0A6J2MUN1
uniprot id: A0A7E6CHU5
uniprot id: A0A7E6CHY4
uniprot id: A0A7E6CI88
uniprot id: A0A7E6CJX0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114490173
gene id: 89673:LOC114490173
uniprot id: A0A6J2KWW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:OAF
gene id: 89673:OAF
uniprot id: A0A6J2LXD2
names: Similarity
messages: Belongs to the OAF family.

89673:LOC114500298
gene id: 89673:LOC114500298
uniprot id: A0A6J2M3F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:GALK1
gene id: 89673:GALK1
uniprot id: A0A6J2M8C7
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

89673:LOC114501816
gene id: 89673:LOC114501816
uniprot id: A0A7E6CHF7
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

89673:KRT71
gene id: 89673:KRT71
uniprot id: A0A6J2N8P2
uniprot id: A0A7E6D6K7
names: Similarity
messages: Belongs to the intermediate filament family.

89673:ATP5PO
gene id: 89673:ATP5PO
uniprot id: A0A6J2KWI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion inner membrane

89673:SPDL1
gene id: 89673:SPDL1
uniprot id: A0A6J2MX34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Spindly family.
messages: Interacts with KNTC1 and ZW10. These interactions appear weak and may be transient or indirect.
messages: Nucleus
messages: Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment.
messages: centrosome
messages: kinetochore
messages: spindle pole

89673:GSX1
gene id: 89673:GSX1
uniprot id: A0A6J2KX57
names: Subcellular Location Annotation
messages: Nucleus

89673:NDC80
gene id: 89673:NDC80
uniprot id: A0A6J2MM63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the NDC80/HEC1 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

89673:NKX6-2
gene id: 89673:NKX6-2
uniprot id: A0A6J2LVF3
names: Subcellular Location Annotation
messages: Nucleus

89673:MGAM
gene id: 89673:MGAM
uniprot id: A0A7E6CJ18
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:KCNB1
gene id: 89673:KCNB1
uniprot id: A0A6J2MPZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.1/KCNB1 sub-subfamily.
messages: Lateral cell membrane
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: axon
messages: dendrite
messages: sarcolemma
messages: synaptosome

89673:LOC118496655
gene id: 89673:LOC118496655
uniprot id: A0A7E6E0J4
names: Function
names: Similarity
messages: Belongs to the SAA family.
messages: Major acute phase reactant. Apolipoprotein of the HDL complex.

89673:LOC114511971
gene id: 89673:LOC114511971
uniprot id: A0A6J2N9K8
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion membrane

89673:CHRNA5
gene id: 89673:CHRNA5
uniprot id: A0A7E6CQ47
uniprot id: A0A7E6CQB5
uniprot id: A0A7E6CQG8
uniprot id: A0A7E6CQH3
uniprot id: A0A7E6CSL6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

89673:MTCP1
gene id: 89673:MTCP1
uniprot id: A0A6J2MK25
names: Similarity
messages: Belongs to the TCL1 family.

89673:SLC10A7
gene id: 89673:SLC10A7
uniprot id: A0A6J2MHN4
uniprot id: A0A7E6E9Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Cell membrane
messages: Does not show transport activity towards bile acids or steroid sulfates.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

89673:LOC114489876
gene id: 89673:LOC114489876
uniprot id: A0A7E6D1N7
names: Subcellular Location Annotation
messages: Membrane

89673:MGRN1
gene id: 89673:MGRN1
uniprot id: A0A6J2LRC3
uniprot id: A0A6J2LUE9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin ligase.

89673:AQP1
gene id: 89673:AQP1
uniprot id: A0A6J2MPW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

89673:SLCO2A1
gene id: 89673:SLCO2A1
uniprot id: A0A6J2M776
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:TSPOAP1
gene id: 89673:TSPOAP1
uniprot id: A0A7E6EDA3
uniprot id: A0A7E6EDV4
uniprot id: A0A7E6EE06
uniprot id: A0A7E6EEV0
uniprot id: A0A7E6EF20
names: Similarity
messages: Belongs to the RIMBP family.

89673:CCN4
gene id: 89673:CCN4
uniprot id: A0A7E6E8C1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:CDR2
gene id: 89673:CDR2
uniprot id: A0A6J2N5U8
names: Similarity
messages: Belongs to the CDR2 family.

89673:GPR132
gene id: 89673:GPR132
uniprot id: A0A7E6D2V4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:TSPAN33
gene id: 89673:TSPAN33
uniprot id: A0A6J2MPJ0
uniprot id: A0A7E6CIM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

89673:GLYAT
gene id: 89673:GLYAT
uniprot id: A0A6J2M0E8
uniprot id: A0A7E6E211
uniprot id: A0A7E6E257
uniprot id: A0A7E6E2V4
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

89673:PITX2
gene id: 89673:PITX2
uniprot id: A0A6J2L891
uniprot id: A0A6J2LA14
uniprot id: A0A6J2LCW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

89673:LOC114492764
gene id: 89673:LOC114492764
uniprot id: A0A7E6CGQ8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

89673:EIF3H
gene id: 89673:EIF3H
uniprot id: A0A6J2NDF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit H family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with RNF139; the interaction leads to protein translation inhibitions in a ubiquitination-dependent manner.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm

89673:PPIL1
gene id: 89673:PPIL1
uniprot id: A0A6J2LK77
uniprot id: A0A7E6DLC6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

89673:CCNH
gene id: 89673:CCNH
uniprot id: A0A6J2MXX1
uniprot id: A0A7E6DAM9
names: Function
names: Similarity
names: Subunit
messages: Associates primarily with CDK7 and MAT1 to form the CAK complex. CAK can further associate with the core-TFIIH to form the TFIIH basal transcription factor.
messages: Belongs to the cyclin family. Cyclin C subfamily.
messages: Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

89673:LOC114492614
gene id: 89673:LOC114492614
uniprot id: A0A6J2LB36
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114511674
gene id: 89673:LOC114511674
uniprot id: A0A7E6DA01
names: Similarity
messages: Belongs to the heat shock protein 70 family.

89673:CCR10
gene id: 89673:CCR10
uniprot id: A0A7E6CDY3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:IDH3B
gene id: 89673:IDH3B
uniprot id: A0A6J2MJ57
uniprot id: A0A6J2MNA9
uniprot id: A0A7E6CF14
uniprot id: A0A7E6CFJ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

89673:TRAK2
gene id: 89673:TRAK2
uniprot id: A0A6J2L943
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the milton family.
messages: Early endosome
messages: Mitochondrion

89673:BOLA1
gene id: 89673:BOLA1
uniprot id: A0A6J2KV98
names: Similarity
messages: Belongs to the BolA/IbaG family.

89673:FAM171A2
gene id: 89673:FAM171A2
uniprot id: A0A6J2MFJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

89673:LOC114489485
gene id: 89673:LOC114489485
uniprot id: A0A6J2KV38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

89673:LOC114512999
gene id: 89673:LOC114512999
uniprot id: A0A6J2N7Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:NAB1
gene id: 89673:NAB1
uniprot id: A0A6J2L9Z4
uniprot id: A0A6J2LAJ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAB family.
messages: Homomultimers may associate with EGR1 bound to DNA.
messages: Nucleus

89673:WDR4
gene id: 89673:WDR4
uniprot id: A0A6J2KZ12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat TRM82 family.
messages: Nucleus
messages: Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

89673:LOC114500224
gene id: 89673:LOC114500224
uniprot id: A0A6J2M3M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ITGAV
gene id: 89673:ITGAV
uniprot id: A0A6J2LC50
uniprot id: A0A6J2LFZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

89673:DMBT1
gene id: 89673:DMBT1
uniprot id: A0A7E6DVQ6
names: Caution
names: Similarity
messages: Belongs to the DMBT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114507846
gene id: 89673:LOC114507846
uniprot id: A0A6J2MUN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:MRPL16
gene id: 89673:MRPL16
uniprot id: A0A6J2M054
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

89673:SDC1
gene id: 89673:SDC1
uniprot id: A0A6J2LWD4
uniprot id: A0A7E6DWM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

89673:TACC2
gene id: 89673:TACC2
uniprot id: A0A6J2LMQ0
uniprot id: A0A6J2LP14
uniprot id: A0A6J2LT14
uniprot id: A0A7E6DVP7
uniprot id: A0A7E6DWA8
uniprot id: A0A7E6DX51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

89673:PSME4
gene id: 89673:PSME4
uniprot id: A0A6J2M2K8
uniprot id: A0A7E6DX84
names: Similarity
messages: Belongs to the BLM10 family.

89673:MAP4K2
gene id: 89673:MAP4K2
uniprot id: A0A6J2LZP0
uniprot id: A0A7E6E2L1
uniprot id: A0A7E6E2S5
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

89673:EGFLAM
gene id: 89673:EGFLAM
uniprot id: A0A7E6DA53
uniprot id: A0A7E6DAV4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:ST6GALNAC2
gene id: 89673:ST6GALNAC2
uniprot id: A0A6J2MEY3
uniprot id: A0A7E6EEP2
uniprot id: A0A7E6EF77
uniprot id: A0A7E6EFH8
uniprot id: A0A7E6EG97
uniprot id: A0A7E6EGG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

89673:RPS27A
gene id: 89673:RPS27A
uniprot id: A0A6J2LYK9
names: Similarity
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.

89673:PTGFR
gene id: 89673:PTGFR
uniprot id: A0A6J2LP20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:PABPC4
gene id: 89673:PABPC4
uniprot id: A0A6J2LPN5
uniprot id: A0A6J2LQV0
uniprot id: A0A6J2LRV3
uniprot id: A0A6J2LV45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

89673:LOC114498733
gene id: 89673:LOC114498733
uniprot id: A0A7E6E498
names: Similarity
messages: Belongs to the SKP1 family.

89673:LOC114493134
gene id: 89673:LOC114493134
uniprot id: A0A6J2L7K6
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

89673:MYCN
gene id: 89673:MYCN
uniprot id: A0A6J2LWP3
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

89673:CDC25C
gene id: 89673:CDC25C
uniprot id: A0A7E6CS63
uniprot id: A0A7E6CSK9
uniprot id: A0A7E6CSU9
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

89673:NXPH2
gene id: 89673:NXPH2
uniprot id: A0A7E6DKD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

89673:METTL14
gene id: 89673:METTL14
uniprot id: A0A6J2M914
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MT-A70-like family.
messages: Heterodimer; heterodimerizes with METTL3 to form an antiparallel heterodimer that constitutes an active methyltransferase.
messages: Nucleus
messages: The METTL3-METTL14 heterodimer forms a N6-methyltransferase complex that methylates adenosine residues at the N(6) position of some mRNAs and regulates the circadian clock, differentiation of embryonic stem cells and cortical neurogenesis. In the heterodimer formed with METTL3, METTL14 constitutes the RNA-binding scaffold that recognizes the substrate rather than the catalytic core. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in mRNA stability and processing. M6A acts as a key regulator of mRNA stability by promoting mRNA destabilization and degradation. In embryonic stem cells (ESCs), m6A methylation of mRNAs encoding key naive pluripotency-promoting transcripts results in transcript destabilization. M6A regulates spermatogonial differentiation and meiosis and is essential for male fertility and spermatogenesis. M6A also regulates cortical neurogenesis: m6A methylation of transcripts related to transcription factors, neural stem cells, the cell cycle and neuronal differentiation during brain development promotes their destabilization and decay, promoting differentiation of radial glial cells.

89673:WNT11
gene id: 89673:WNT11
uniprot id: A0A6J2LVL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

89673:MFSD9
gene id: 89673:MFSD9
uniprot id: A0A6J2M080
names: Subcellular Location Annotation
messages: Membrane

89673:STAT2
gene id: 89673:STAT2
uniprot id: A0A6J2N949
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

89673:DAO
gene id: 89673:DAO
uniprot id: A0A6J2N3C4
uniprot id: A0A7E6CS62
uniprot id: A0A7E6CSU7
uniprot id: A0A7E6CUU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

89673:CRY2
gene id: 89673:CRY2
uniprot id: A0A7E6E2A5
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 FAD per subunit.

89673:SARS2
gene id: 89673:SARS2
uniprot id: A0A6J2N0B1
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.

89673:SMPDL3A
gene id: 89673:SMPDL3A
uniprot id: A0A6J2LEN0
uniprot id: A0A7E6DN04
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) per subunit.
messages: Secreted

89673:DIMT1
gene id: 89673:DIMT1
uniprot id: A0A6J2MGB6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

89673:LOC114500549
gene id: 89673:LOC114500549
uniprot id: A0A7E6E0X2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:GDF3
gene id: 89673:GDF3
uniprot id: A0A6J2NEY7
names: Similarity
messages: Belongs to the TGF-beta family.

89673:LOC114508150
gene id: 89673:LOC114508150
uniprot id: A0A7E6CJ17
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

89673:AHCY
gene id: 89673:AHCY
uniprot id: A0A6J2MPI3
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

89673:EBF2
gene id: 89673:EBF2
uniprot id: A0A6J2MDR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

89673:AGBL5
gene id: 89673:AGBL5
uniprot id: A0A6J2LZG5
uniprot id: A0A7E6DX80
uniprot id: A0A7E6DY34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Midbody
messages: Nucleus
messages: cytosol
messages: spindle

89673:HS6ST3
gene id: 89673:HS6ST3
uniprot id: A0A6J2MXK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

89673:LOC114490269
gene id: 89673:LOC114490269
uniprot id: A0A7E6E6L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:GABRB3
gene id: 89673:GABRB3
uniprot id: A0A6J2KXU7
uniprot id: A0A7E6CP45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

89673:LOC114503445
gene id: 89673:LOC114503445
uniprot id: A0A6J2M9X1
uniprot id: A0A6J2MC51
uniprot id: A0A7E6EBQ4
names: Similarity
messages: Belongs to the cytochrome P450 family.

89673:PTPRT
gene id: 89673:PTPRT
uniprot id: A0A6J2MM43
uniprot id: A0A6J2MMB8
uniprot id: A0A7E6CFH9
uniprot id: A0A7E6CFJ5
uniprot id: A0A7E6CFK0
uniprot id: A0A7E6CFN5
uniprot id: A0A7E6CFP2
uniprot id: A0A7E6CG33
uniprot id: A0A7E6CG37
uniprot id: A0A7E6CHN3
uniprot id: A0A7E6CHN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Membrane

89673:PACS2
gene id: 89673:PACS2
uniprot id: A0A6J2L8P5
uniprot id: A0A7E6CT51
uniprot id: A0A7E6CT58
uniprot id: A0A7E6CT71
uniprot id: A0A7E6CVZ0
uniprot id: A0A7E6CW05
names: Similarity
messages: Belongs to the PACS family.

89673:LOC114500604
gene id: 89673:LOC114500604
uniprot id: A0A6J2LZD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114494223
gene id: 89673:LOC114494223
uniprot id: A0A6J2LFX2
uniprot id: A0A7E6DLI8
names: Similarity
messages: Belongs to the BZW family.

89673:RAPGEF2
gene id: 89673:RAPGEF2
uniprot id: A0A6J2MDF3
uniprot id: A0A6J2MDF5
uniprot id: A0A6J2MGD2
uniprot id: A0A6J2MH62
uniprot id: A0A7E6E887
uniprot id: A0A7E6E893
uniprot id: A0A7E6E906
uniprot id: A0A7E6E909
uniprot id: A0A7E6E972
uniprot id: A0A7E6E9U1
uniprot id: A0A7E6E9U5
uniprot id: A0A7E6EA71
uniprot id: A0A7E6EA80
names: Similarity
messages: Belongs to the RAPGEF2 family.

89673:NIPA1
gene id: 89673:NIPA1
uniprot id: A0A6J2KW89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

89673:LOC114503633
gene id: 89673:LOC114503633
uniprot id: A0A7E6EA72
uniprot id: A0A7E6EAS4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:TSNAX
gene id: 89673:TSNAX
uniprot id: A0A6J2N3E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the translin family.
messages: Nucleus

89673:CENPC
gene id: 89673:CENPC
uniprot id: A0A6J2L552
uniprot id: A0A7E6DCL0
uniprot id: A0A7E6DCR9
uniprot id: A0A7E6DCS3
uniprot id: A0A7E6DD20
uniprot id: A0A7E6DDC3
names: Similarity
messages: Belongs to the CENP-C/MIF2 family.

89673:MYB
gene id: 89673:MYB
uniprot id: A0A6J2LGP3
uniprot id: A0A6J2LHV0
uniprot id: A0A7E6DP02
uniprot id: A0A7E6DPA8
names: Subcellular Location Annotation
messages: Nucleus

89673:ZNF592
gene id: 89673:ZNF592
uniprot id: A0A6J2KSR2
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

89673:ATP9A
gene id: 89673:ATP9A
uniprot id: A0A6J2MPV0
uniprot id: A0A7E6CFX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

89673:CTBP1
gene id: 89673:CTBP1
uniprot id: A0A6J2L1Y8
uniprot id: A0A7E6D3H0
uniprot id: A0A7E6D3J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

89673:LOC114490191
gene id: 89673:LOC114490191
uniprot id: A0A6J2KZ59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114511433
gene id: 89673:LOC114511433
uniprot id: A0A7E6CP04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA5 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

89673:PPDPF
gene id: 89673:PPDPF
uniprot id: A0A6J2MR49
uniprot id: A0A7E6CGJ7
names: Similarity
messages: Belongs to the PPDPF family.

89673:ZRANB1
gene id: 89673:ZRANB1
uniprot id: A0A6J2LLM1
names: Similarity
messages: Belongs to the peptidase C64 family.

89673:MYO5B
gene id: 89673:MYO5B
uniprot id: A0A7E6CGL7
uniprot id: A0A7E6CIT8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

89673:OTULINL
gene id: 89673:OTULINL
uniprot id: A0A6J2MDF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C65 family. Otulin subfamily.
messages: Cytoplasm

89673:FTO
gene id: 89673:FTO
uniprot id: A0A6J2KXC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fto family.
messages: Cytoplasm
messages: Nucleus speckle

89673:SEPTIN3
gene id: 89673:SEPTIN3
uniprot id: A0A6J2N7U8
uniprot id: A0A6J2NCB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cytoplasm
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

89673:HS3ST2
gene id: 89673:HS3ST2
uniprot id: A0A6J2MGH1
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

89673:ST6GAL2
gene id: 89673:ST6GAL2
uniprot id: A0A6J2LQ46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

89673:APAF1
gene id: 89673:APAF1
uniprot id: A0A6J2N7H1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Monomer. Oligomerizes upon binding of cytochrome c and dATP.
messages: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.

89673:LOC114512023
gene id: 89673:LOC114512023
uniprot id: A0A6J2N4E0
uniprot id: A0A6J2N922
uniprot id: A0A7E6CXL7
uniprot id: A0A7E6CZS8
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: acrosome inner membrane

89673:LOC114488933
gene id: 89673:LOC114488933
uniprot id: A0A7E6CVN2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

89673:SLC1A7
gene id: 89673:SLC1A7
uniprot id: A0A6J2LPA9
uniprot id: A0A7E6DS04
uniprot id: A0A7E6DS33
uniprot id: A0A7E6DSS9
uniprot id: A0A7E6DT69
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:GALNS
gene id: 89673:GALNS
uniprot id: A0A6J2KWS6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Homodimer.
messages: Lysosome

89673:RAD21
gene id: 89673:RAD21
uniprot id: A0A6J2NGV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

89673:ADCYAP1R1
gene id: 89673:ADCYAP1R1
uniprot id: A0A6J2MMM7
uniprot id: A0A6J2MPI1
uniprot id: A0A6J2MPJ5
uniprot id: A0A7E6CHC0
names: Subcellular Location Annotation
messages: Membrane

89673:FMO5
gene id: 89673:FMO5
uniprot id: A0A6J2KTB4
uniprot id: A0A7E6CXB8
uniprot id: A0A7E6CXF2
uniprot id: A0A7E6D009
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

89673:PUF60
gene id: 89673:PUF60
uniprot id: A0A6J2NAM1
uniprot id: A0A6J2NCA8
uniprot id: A0A6J2NCJ1
uniprot id: A0A6J2NCK5
uniprot id: A0A6J2NI28
uniprot id: A0A6J2NI32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM half pint family.
messages: Nucleus

89673:MPP5
gene id: 89673:MPP5
uniprot id: A0A6J2L4F2
uniprot id: A0A6J2L6H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: Endomembrane system
messages: adherens junction
messages: tight junction

89673:CHST13
gene id: 89673:CHST13
uniprot id: A0A6J2MJ35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

89673:SCAMP1
gene id: 89673:SCAMP1
uniprot id: A0A6J2LN94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

89673:PSMB6
gene id: 89673:PSMB6
uniprot id: A0A6J2NE43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

89673:EXOC8
gene id: 89673:EXOC8
uniprot id: A0A6J2N5K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EXO84 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: growth cone
messages: perinuclear region

89673:RCAN3
gene id: 89673:RCAN3
uniprot id: A0A6J2LQL5
names: Similarity
messages: Belongs to the RCAN family.

89673:AP3D1
gene id: 89673:AP3D1
uniprot id: A0A6J2M6W0
uniprot id: A0A7E6E8T6
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

89673:RPS3
gene id: 89673:RPS3
uniprot id: A0A6J2LXS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: spindle

89673:LOC114495588
gene id: 89673:LOC114495588
uniprot id: A0A6J2LKY9
uniprot id: A0A7E6D973
uniprot id: A0A7E6D9A6
uniprot id: A0A7E6D9G7
uniprot id: A0A7E6DA56
names: Similarity
messages: Belongs to the peptidase C14A family.

89673:FERMT1
gene id: 89673:FERMT1
uniprot id: A0A6J2MPI9
uniprot id: A0A7E6CEU9
uniprot id: A0A7E6CFD2
names: Similarity
messages: Belongs to the kindlin family.

89673:NPY5R
gene id: 89673:NPY5R
uniprot id: A0A6J2MAH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders.

89673:DZIP3
gene id: 89673:DZIP3
uniprot id: A0A6J2KU29
names: Subcellular Location Annotation
messages: Cytoplasm

89673:NR1H2
gene id: 89673:NR1H2
uniprot id: A0A6J2MZ25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

89673:CD79B
gene id: 89673:CD79B
uniprot id: A0A7E6ECU8
uniprot id: A0A7E6EDD4
uniprot id: A0A7E6EEK9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:SPO11
gene id: 89673:SPO11
uniprot id: A0A6J2MS58
names: Similarity
messages: Belongs to the TOP6A family.

89673:LOC114508966
gene id: 89673:LOC114508966
uniprot id: A0A6J2MYJ4
uniprot id: A0A7E6DGY0
names: Similarity
messages: Belongs to the ficolin lectin family.

89673:EXOC5
gene id: 89673:EXOC5
uniprot id: A0A6J2L6T6
names: Similarity
messages: Belongs to the SEC10 family.

89673:ADGRA1
gene id: 89673:ADGRA1
uniprot id: A0A7E6DW19
names: Subcellular Location Annotation
messages: Membrane

89673:MDH1
gene id: 89673:MDH1
uniprot id: A0A6J2LV44
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Homodimer.

89673:LOC114493871
gene id: 89673:LOC114493871
uniprot id: A0A6J2LA93
names: Similarity
messages: Belongs to the MHC class I family.

89673:MMUT
gene id: 89673:MMUT
uniprot id: A0A6J2LCE0
uniprot id: A0A7E6DMJ5
names: Function
names: Similarity
messages: Belongs to the methylmalonyl-CoA mutase family.
messages: Catalyzes the reversible isomerization of methylmalonyl-CoA (MMCoA) (generated from branched-chain amino acid metabolism and degradation of dietary odd chain fatty acids and cholesterol) to succinyl-CoA (3-carboxypropionyl-CoA), a key intermediate of the tricarboxylic acid cycle.

89673:MCM7
gene id: 89673:MCM7
uniprot id: A0A6J2LLI0
uniprot id: A0A6J2LMA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Nucleus

89673:MMACHC
gene id: 89673:MMACHC
uniprot id: A0A6J2LQX0
uniprot id: A0A7E6DSV6
names: Similarity
messages: Belongs to the MMACHC family.

89673:SURF6
gene id: 89673:SURF6
uniprot id: A0A6J2M6M2
uniprot id: A0A7E6DH65
names: Similarity
messages: Belongs to the SURF6 family.

89673:LOC114489501
gene id: 89673:LOC114489501
uniprot id: A0A7E6CXF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CDC42EP2
gene id: 89673:CDC42EP2
uniprot id: A0A6J2LZF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system
messages: Probably involved in the organization of the actin cytoskeleton.
messages: cytoskeleton

89673:LOC114498934
gene id: 89673:LOC114498934
uniprot id: A0A6J2LUN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:FZD10
gene id: 89673:FZD10
uniprot id: A0A6J2KVL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

89673:CDC42EP1
gene id: 89673:CDC42EP1
uniprot id: A0A6J2NCN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

89673:CPNE7
gene id: 89673:CPNE7
uniprot id: A0A7E6CSX0
names: Similarity
messages: Belongs to the copine family.

89673:INA
gene id: 89673:INA
uniprot id: A0A6J2LPF2
names: Similarity
messages: Belongs to the intermediate filament family.

89673:MED29
gene id: 89673:MED29
uniprot id: A0A6J2N623
uniprot id: A0A7E6CLB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 29 family.
messages: Nucleus

89673:LOC114513927
gene id: 89673:LOC114513927
uniprot id: A0A6J2N9A2
names: Similarity
messages: Belongs to the apolipoprotein L family.

89673:TSC22D3
gene id: 89673:TSC22D3
uniprot id: A0A6J2MII7
uniprot id: A0A6J2MN02
uniprot id: A0A7E6D0M5
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

89673:PBRM1
gene id: 89673:PBRM1
uniprot id: A0A7E6E6Z3
names: Subcellular Location Annotation
messages: Nucleus

89673:SLC25A19
gene id: 89673:SLC25A19
uniprot id: A0A6J2MAR2
uniprot id: A0A7E6EFC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

89673:TXNDC5
gene id: 89673:TXNDC5
uniprot id: A0A6J2LPW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

89673:LOC114500111
gene id: 89673:LOC114500111
uniprot id: A0A6J2LZP7
names: Similarity
messages: Belongs to the CD225/Dispanin family.

89673:RFLNB
gene id: 89673:RFLNB
uniprot id: A0A6J2M9V5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Refilin family.
messages: Interacts with FLNA and FLNB.
messages: cytoskeleton

89673:LOC114490204
gene id: 89673:LOC114490204
uniprot id: A0A6J2KXI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114497112
gene id: 89673:LOC114497112
uniprot id: A0A7E6DVY7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

89673:LOC114499071
gene id: 89673:LOC114499071
uniprot id: A0A6J2LSU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ZER1
gene id: 89673:ZER1
uniprot id: A0A7E6DGT6
uniprot id: A0A7E6DGX0
names: Similarity
messages: Belongs to the zyg-11 family.

89673:CENPA
gene id: 89673:CENPA
uniprot id: A0A7E6DX67
names: Similarity
messages: Belongs to the histone H3 family.

89673:LOC114493019
gene id: 89673:LOC114493019
uniprot id: A0A6J2L8Y1
uniprot id: A0A7E6DFT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

89673:NMNAT1
gene id: 89673:NMNAT1
uniprot id: A0A6J2LPX2
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

89673:LOC114515157
gene id: 89673:LOC114515157
uniprot id: A0A6J2NJL5
names: Caution
names: Cofactor
messages: Binds 1 Fe cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:ATL1
gene id: 89673:ATL1
uniprot id: A0A6J2LCU8
uniprot id: A0A6J2LDW2
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

89673:NPM3
gene id: 89673:NPM3
uniprot id: A0A6J2LNS0
names: Similarity
messages: Belongs to the nucleoplasmin family.

89673:TSC22D2
gene id: 89673:TSC22D2
uniprot id: A0A6J2NE84
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

89673:CPSF7
gene id: 89673:CPSF7
uniprot id: A0A6J2LSW0
uniprot id: A0A6J2LTQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CPSF6/7 family.
messages: Nucleus

89673:TPRG1L
gene id: 89673:TPRG1L
uniprot id: A0A6J2LKP7
names: Similarity
messages: Belongs to the TPRG1 family.

89673:TMEM9B
gene id: 89673:TMEM9B
uniprot id: A0A6J2LYG9
uniprot id: A0A6J2LZK5
uniprot id: A0A6J2M0J7
names: Similarity
messages: Belongs to the TMEM9 family.

89673:BABAM2
gene id: 89673:BABAM2
uniprot id: A0A6J2M1B6
uniprot id: A0A7E6DWR9
uniprot id: A0A7E6DXR9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BABAM2 family.
messages: Component of the ARISC complex. Component of the BRCA1-A complex. Component of the BRISC complex. Binds polyubiquitin.
messages: Contains 2 ubiquitin-conjugating enzyme family-like (UEV-like) regions. These regions lack the critical Cys residues required for ubiquitination but retain the ability to bind ubiquitin.
messages: Cytoplasm
messages: May play a role in homeostasis or cellular differentiation in cells of neural, epithelial and germline origins. May also act as a death receptor-associated anti-apoptotic protein, which inhibits the mitochondrial apoptotic pathway.
messages: Nucleus

89673:GABRQ
gene id: 89673:GABRQ
uniprot id: A0A6J2MK10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

89673:LOC114493989
gene id: 89673:LOC114493989
uniprot id: A0A6J2LB16
names: Similarity
messages: Belongs to the fl(2)d family.

89673:YJU2
gene id: 89673:YJU2
uniprot id: A0A6J2LCQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CWC16 family. YJU2 subfamily.
messages: Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.
messages: Nucleus
messages: Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex.

89673:SLCO4A1
gene id: 89673:SLCO4A1
uniprot id: A0A6J2MMH5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:LOC114513465
gene id: 89673:LOC114513465
uniprot id: A0A6J2NEJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ELOVL1
gene id: 89673:ELOVL1
uniprot id: A0A6J2LNT4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ELO family. ELOVL1 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs.
messages: Endoplasmic reticulum membrane
messages: Interacts with LASS2, TECR and HSD17B12.
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

89673:VPS52
gene id: 89673:VPS52
uniprot id: A0A6J2LJW6
uniprot id: A0A7E6DL25
uniprot id: A0A7E6DL26
uniprot id: A0A7E6DLT0
names: Similarity
messages: Belongs to the VPS52 family.

89673:TMEM151B
gene id: 89673:TMEM151B
uniprot id: A0A6J2LFY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM151 family.
messages: Membrane

89673:POU1F1
gene id: 89673:POU1F1
uniprot id: A0A6J2KZC2
uniprot id: A0A6J2L3G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

89673:HSD17B3
gene id: 89673:HSD17B3
uniprot id: A0A6J2N5W4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

89673:UBE3D
gene id: 89673:UBE3D
uniprot id: A0A6J2LBY3
uniprot id: A0A7E6DMD3
uniprot id: A0A7E6DME1
uniprot id: A0A7E6DMW7
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.

89673:PNPLA6
gene id: 89673:PNPLA6
uniprot id: A0A6J2MT56
uniprot id: A0A6J2MUR9
uniprot id: A0A6J2MUT2
uniprot id: A0A7E6CTC0
uniprot id: A0A7E6CTC4
uniprot id: A0A7E6CTU9
uniprot id: A0A7E6CTV4
uniprot id: A0A7E6CU45
uniprot id: A0A7E6CU50
uniprot id: A0A7E6CW62
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:UCHL1
gene id: 89673:UCHL1
uniprot id: A0A6J2L433
uniprot id: A0A6J2L4Q9
names: Similarity
messages: Belongs to the peptidase C12 family.

89673:SATB1
gene id: 89673:SATB1
uniprot id: A0A6J2M1E2
uniprot id: A0A6J2M2V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

89673:ACTN1
gene id: 89673:ACTN1
uniprot id: A0A6J2L3W1
uniprot id: A0A6J2L5V8
uniprot id: A0A6J2L765
names: Similarity
messages: Belongs to the alpha-actinin family.

89673:LOC114489249
gene id: 89673:LOC114489249
uniprot id: A0A7E6CYW0
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:TMED4
gene id: 89673:TMED4
uniprot id: A0A6J2KXM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:CACNG4
gene id: 89673:CACNG4
uniprot id: A0A6J2M9D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization.

89673:POU5F1
gene id: 89673:POU5F1
uniprot id: A0A6J2LFN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

89673:CFDP1
gene id: 89673:CFDP1
uniprot id: A0A6J2KTE0
uniprot id: A0A7E6CMG8
names: Function
names: Subcellular Location Annotation
messages: May play a role during embryogenesis.
messages: kinetochore

89673:LOC114501665
gene id: 89673:LOC114501665
uniprot id: A0A7E6E4L4
uniprot id: A0A7E6E4R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SCAP family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

89673:ADCY4
gene id: 89673:ADCY4
uniprot id: A0A6J2LCD6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

89673:TENM2
gene id: 89673:TENM2
uniprot id: A0A6J2MWM7
uniprot id: A0A7E6CT95
uniprot id: A0A7E6CTS0
uniprot id: A0A7E6CU14
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:MINPP1
gene id: 89673:MINPP1
uniprot id: A0A6J2LPL1
names: Similarity
messages: Belongs to the histidine acid phosphatase family. MINPP1 subfamily.

89673:ADAT2
gene id: 89673:ADAT2
uniprot id: A0A6J2LKE4
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family. ADAT2 subfamily.
messages: Probably participates in deamination of adenosine-34 to inosine in many tRNAs.

89673:RNF112
gene id: 89673:RNF112
uniprot id: A0A6J2NEB2
uniprot id: A0A7E6EAY5
uniprot id: A0A7E6EAZ0
uniprot id: A0A7E6EBR5
uniprot id: A0A7E6EBU1
uniprot id: A0A7E6ECV4
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

89673:LOC114510352
gene id: 89673:LOC114510352
uniprot id: A0A6J2MYV0
uniprot id: A0A7E6CSX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114499660
gene id: 89673:LOC114499660
uniprot id: A0A7E6DXC4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

89673:ILVBL
gene id: 89673:ILVBL
uniprot id: A0A6J2M707
names: Similarity
messages: Belongs to the TPP enzyme family.

89673:SLC25A33
gene id: 89673:SLC25A33
uniprot id: A0A6J2LMB5
uniprot id: A0A7E6DPR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

89673:CAND1
gene id: 89673:CAND1
uniprot id: A0A6J2NCF5
names: Similarity
messages: Belongs to the CAND family.

89673:QKI
gene id: 89673:QKI
uniprot id: A0A7E6DNW3
uniprot id: A0A7E6DPE5
uniprot id: A0A7E6DPJ9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer. Does not require RNA to homodimerize. Able to heterodimerize with BICC1.
messages: Nucleus
messages: RNA-binding protein that plays a central role in myelinization. Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B which promotes oligodendrocyte differentiation. Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor.

89673:GJA8
gene id: 89673:GJA8
uniprot id: A0A6J2KY72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

89673:PRIM2
gene id: 89673:PRIM2
uniprot id: A0A6J2LHJ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.

89673:POU3F3
gene id: 89673:POU3F3
uniprot id: A0A6J2LX98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

89673:MPP3
gene id: 89673:MPP3
uniprot id: A0A6J2MB91
uniprot id: A0A7E6EFW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane

89673:CAVIN3
gene id: 89673:CAVIN3
uniprot id: A0A6J2M0X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

89673:LOC114506931
gene id: 89673:LOC114506931
uniprot id: A0A6J2MRS9
names: Subcellular Location Annotation
messages: Membrane

89673:SSBP2
gene id: 89673:SSBP2
uniprot id: A0A6J2L9A5
uniprot id: A0A6J2L9B4
uniprot id: A0A6J2LDT6
uniprot id: A0A6J2LDW4
uniprot id: A0A6J2LEX5
uniprot id: A0A7E6DAL6
uniprot id: A0A7E6DD88
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114500538
gene id: 89673:LOC114500538
uniprot id: A0A6J2M481
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114498719
gene id: 89673:LOC114498719
uniprot id: A0A6J2LTG2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

89673:ATOH7
gene id: 89673:ATOH7
uniprot id: A0A7E6DPQ7
names: Subcellular Location Annotation
messages: Nucleus
messages: Perikaryon
messages: axon

89673:TIMP2
gene id: 89673:TIMP2
uniprot id: A0A6J2M9A9
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

89673:EMC3
gene id: 89673:EMC3
uniprot id: A0A6J2M833
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC3 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

89673:LOC114496610
gene id: 89673:LOC114496610
uniprot id: A0A6J2LQA4
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

89673:LOC114489059
gene id: 89673:LOC114489059
uniprot id: A0A7E6CVT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM237 family.
messages: Component of the transition zone in primary cilia. Required for ciliogenesis.
messages: Membrane
messages: cilium

89673:SLC47A2
gene id: 89673:SLC47A2
uniprot id: A0A7E6EBS4
uniprot id: A0A7E6EBV0
uniprot id: A0A7E6ECW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

89673:MYO3B
gene id: 89673:MYO3B
uniprot id: A0A7E6DJV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: In the C-terminal section; belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: cytoskeleton

89673:CLDN19
gene id: 89673:CLDN19
uniprot id: A0A6J2LPE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

89673:SPCS3
gene id: 89673:SPCS3
uniprot id: A0A6J2MWK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS3 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:LOC118499859
gene id: 89673:LOC118499859
uniprot id: A0A7E6DHG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

89673:LOC118497649
gene id: 89673:LOC118497649
uniprot id: A0A7E6CNX9
names: Similarity
messages: Belongs to the Speedy/Ringo family.

89673:MMAB
gene id: 89673:MMAB
uniprot id: A0A6J2MV96
uniprot id: A0A7E6CUM4
uniprot id: A0A7E6CUM7
uniprot id: A0A7E6CVF3
uniprot id: A0A7E6CXE9
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

89673:CXCR6
gene id: 89673:CXCR6
uniprot id: A0A6J2M8X2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:PSMD11
gene id: 89673:PSMD11
uniprot id: A0A6J2MB74
names: Similarity
messages: Belongs to the proteasome subunit S9 family.

89673:LOC114510241
gene id: 89673:LOC114510241
uniprot id: A0A6J2MX10
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:KCTD13
gene id: 89673:KCTD13
uniprot id: A0A6J2LDM0
names: Similarity
messages: Belongs to the BACURD family.

89673:RGR
gene id: 89673:RGR
uniprot id: A0A7E6DTT2
uniprot id: A0A7E6DUF1
names: Subcellular Location Annotation
messages: Membrane

89673:UROC1
gene id: 89673:UROC1
uniprot id: A0A6J2MLM8
uniprot id: A0A7E6CE60
uniprot id: A0A7E6CE62
uniprot id: A0A7E6CEB9
uniprot id: A0A7E6CEC3
uniprot id: A0A7E6CEV7
names: Similarity
messages: Belongs to the urocanase family.

89673:APOM
gene id: 89673:APOM
uniprot id: A0A7E6DKS6
uniprot id: A0A7E6DKT0
uniprot id: A0A7E6DL41
uniprot id: A0A7E6DL71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family. Highly divergent.
messages: Interacts with LRP2; LRP2 mediates APOM renal uptake and subsequent lysosomal degradation.
messages: Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid.
messages: Secreted

89673:ENTPD1
gene id: 89673:ENTPD1
uniprot id: A0A6J2LMX7
uniprot id: A0A7E6DUQ9
uniprot id: A0A7E6DVC1
uniprot id: A0A7E6DVN6
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

89673:AP2A2
gene id: 89673:AP2A2
uniprot id: A0A6J2LU29
uniprot id: A0A6J2LZL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit AP2A1 or AP2A2 and beta-type subunit AP2B1), a medium adaptin (mu-type subunit AP2M1) and a small adaptin (sigma-type subunit AP2S1).
messages: Belongs to the adaptor complexes large subunit family.
messages: Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules. AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway. The AP-2 alpha subunit binds polyphosphoinositide-containing lipids, positioning AP-2 on the membrane. The AP-2 alpha subunit acts via its C-terminal appendage domain as a scaffolding platform for endocytic accessory proteins. The AP-2 alpha and AP-2 sigma subunits are thought to contribute to the recognition of the [ED]-X-X-X-L-[LI] motif.
messages: coated pit

89673:GLI1
gene id: 89673:GLI1
uniprot id: A0A6J2NAP0
uniprot id: A0A7E6D5Y7
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

89673:UBE2G2
gene id: 89673:UBE2G2
uniprot id: A0A6J2KYX5
uniprot id: A0A7E6D2E0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

89673:CALR
gene id: 89673:CALR
uniprot id: A0A6J2M8L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calreticulin family.
messages: Endoplasmic reticulum lumen

89673:NCOA7
gene id: 89673:NCOA7
uniprot id: A0A6J2LCU1
uniprot id: A0A6J2LFT2
uniprot id: A0A7E6DN39
names: Similarity
messages: Belongs to the OXR1 family.

89673:HCN2
gene id: 89673:HCN2
uniprot id: A0A6J2MEE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

89673:EVX2
gene id: 89673:EVX2
uniprot id: A0A6J2LJX4
names: Subcellular Location Annotation
messages: Nucleus

89673:CYFIP2
gene id: 89673:CYFIP2
uniprot id: A0A6J2MSB9
uniprot id: A0A6J2MYK2
names: Similarity
messages: Belongs to the CYFIP family.

89673:PPFIA3
gene id: 89673:PPFIA3
uniprot id: A0A6J2N1I3
uniprot id: A0A7E6CNF9
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

89673:TMTC3
gene id: 89673:TMTC3
uniprot id: A0A6J2ND45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

89673:LOC114491858
gene id: 89673:LOC114491858
uniprot id: A0A7E6DDW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Membrane

89673:DAPK3
gene id: 89673:DAPK3
uniprot id: A0A6J2M919
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:LOC114499150
gene id: 89673:LOC114499150
uniprot id: A0A6J2LY29
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

89673:IDO1
gene id: 89673:IDO1
uniprot id: A0A6J2MWB1
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

89673:LOC114509736
gene id: 89673:LOC114509736
uniprot id: A0A6J2MWR5
names: Similarity
messages: Belongs to the MIF family.

89673:LOC114490526
gene id: 89673:LOC114490526
uniprot id: A0A7E6DFA3
names: Similarity
messages: Belongs to the NipSnap family.

89673:SLC44A3
gene id: 89673:SLC44A3
uniprot id: A0A7E6CW36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

89673:LOC118497253
gene id: 89673:LOC118497253
uniprot id: A0A7E6CJE0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114502147
gene id: 89673:LOC114502147
uniprot id: A0A6J2M9P5
names: Similarity
messages: Belongs to the PRR23 family.

89673:LOC114499591
gene id: 89673:LOC114499591
uniprot id: A0A6J2M0F2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

89673:CSPG4
gene id: 89673:CSPG4
uniprot id: A0A7E6CQ23
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LDHD
gene id: 89673:LDHD
uniprot id: A0A6J2KQX1
names: Similarity
messages: Belongs to the FAD-binding oxidoreductase/transferase type 4 family.

89673:ETS2
gene id: 89673:ETS2
uniprot id: A0A6J2L202
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus
messages: Transcription factor.

89673:LMOD1
gene id: 89673:LMOD1
uniprot id: A0A7E6CXV9
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

89673:LOC114489537
gene id: 89673:LOC114489537
uniprot id: A0A6J2L148
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:ALDH18A1
gene id: 89673:ALDH18A1
uniprot id: A0A6J2LI45
uniprot id: A0A6J2LN24
uniprot id: A0A7E6DUQ4
uniprot id: A0A7E6DUU9
names: Similarity
messages: In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
messages: In the N-terminal section; belongs to the glutamate 5-kinase family.

89673:PLA2G2F
gene id: 89673:PLA2G2F
uniprot id: A0A7E6DRA9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

89673:SFRP1
gene id: 89673:SFRP1
uniprot id: A0A6J2MT86
uniprot id: A0A7E6CKQ2
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:TBPL1
gene id: 89673:TBPL1
uniprot id: A0A6J2LD23
names: Similarity
names: Subunit
messages: Belongs to the TBP family.
messages: Binds TFIIA and TFIIB.

89673:MEOX2
gene id: 89673:MEOX2
uniprot id: A0A6J2MQL2
names: Subcellular Location Annotation
messages: Nucleus

89673:HOXB1
gene id: 89673:HOXB1
uniprot id: A0A6J2MBW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family. Labial subfamily.
messages: Nucleus

89673:KDELR2
gene id: 89673:KDELR2
uniprot id: A0A6J2MZL4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:EIF3G
gene id: 89673:EIF3G
uniprot id: A0A6J2MBP1
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit G family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of FRAP1 and RAPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts (via C-terminus) with AIFM1 (via N-terminus).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. This subunit can bind 18S rRNA.
messages: perinuclear region

89673:SLC35D2
gene id: 89673:SLC35D2
uniprot id: A0A6J2N609
uniprot id: A0A7E6DEB1
uniprot id: A0A7E6DEE2
uniprot id: A0A7E6DEF2
uniprot id: A0A7E6DEF4
names: Subcellular Location Annotation
messages: Membrane

89673:RGS2
gene id: 89673:RGS2
uniprot id: A0A6J2N582
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: nucleolus

89673:OSBPL11
gene id: 89673:OSBPL11
uniprot id: A0A6J2KXN4
names: Similarity
messages: Belongs to the OSBP family.

89673:IRF7
gene id: 89673:IRF7
uniprot id: A0A6J2LT46
names: Subcellular Location Annotation
messages: Nucleus

89673:CAMSAP3
gene id: 89673:CAMSAP3
uniprot id: A0A6J2MUL1
uniprot id: A0A6J2MW83
uniprot id: A0A6J2N0U1
uniprot id: A0A7E6CSU4
uniprot id: A0A7E6CSV1
uniprot id: A0A7E6CSV3
uniprot id: A0A7E6CSV6
uniprot id: A0A7E6CTK8
uniprot id: A0A7E6CVL4
uniprot id: A0A7E6CVL9
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

89673:LOC114515361
gene id: 89673:LOC114515361
uniprot id: A0A6J2NDA1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114490436
gene id: 89673:LOC114490436
uniprot id: A0A7E6D3J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA5 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

89673:RNF168
gene id: 89673:RNF168
uniprot id: A0A6J2L5H3
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: According to a well-established model, RNF168 cannot initiate H2A 'Lys-63'-linked ubiquitination and is recruited following RNF8-dependent histone ubiquitination to amplify H2A 'Lys-63'-linked ubiquitination. However, other data suggest that RNF168 is the priming ubiquitin ligase by mediating monoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histone H2A (H2AK13Ub and H2AK15Ub respectively). These data suggest that RNF168 might be recruited to DSBs sites in a RNF8-dependent manner by binding to non-histone proteins ubiquitinated via 'Lys-63'-linked and initiates monoubiquitination of H2A, which is then amplified by RNF8. Additional evidences are however required to confirm these data.
messages: Belongs to the RNF168 family.
messages: E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recruited at DNA interstrand cross-links (ICLs) sites and promotes accumulation of 'Lys-63'-linked ubiquitination of histones H2A and H2AX, leading to recruitment of FAAP20 and Fanconi anemia (FA) complex, followed by interstrand cross-link repair. H2A ubiquitination also mediates the ATM-dependent transcriptional silencing at regions flanking DSBs in cis, a mechanism to avoid collision between transcription and repair intermediates. Also involved in class switch recombination in immune system, via its role in regulation of DSBs repair. Following DNA damage, promotes the ubiquitination and degradation of JMJD2A/KDM4A in collaboration with RNF8, leading to unmask H4K20me2 mark and promote the recruitment of TP53BP1 at DNA damage sites. Not able to initiate 'Lys-63'-linked ubiquitination in vitro; possibly due to partial occlusion of the UBE2N/UBC13-binding region. Catalyzes monoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histone H2A (H2AK13Ub and H2AK15Ub, respectively).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with UBE2N/UBC13.
messages: Nucleus
messages: Sumoylated with SUMO1 by PIAS4 in response to double-strand breaks (DSBs).
messages: The MIU motif (motif interacting with ubiquitin) mediates the interaction with both 'Lys-48'- and 'Lys-63'-linked ubiquitin chains. The UMI motif mediates interaction with ubiquitin with a preference for 'Lys-63'-linked ubiquitin. The specificity for different types of ubiquitin is mediated by juxtaposition of ubiquitin-binding motifs (MIU and UMI motifs) with LR motifs (LRMs).
messages: Ubiquitinated.

89673:LOC114513054
gene id: 89673:LOC114513054
uniprot id: A0A7E6D6V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:SEC11C
gene id: 89673:SEC11C
uniprot id: A0A6J2MPR8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Component of the signal peptidase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:CCBE1
gene id: 89673:CCBE1
uniprot id: A0A6J2MLT5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:F12
gene id: 89673:F12
uniprot id: A0A7E6CS73
uniprot id: A0A7E6CS76
uniprot id: A0A7E6CSW1
uniprot id: A0A7E6CUW2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

89673:B4GALT3
gene id: 89673:B4GALT3
uniprot id: A0A6J2L0U8
uniprot id: A0A7E6CX07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

89673:KIAA1191
gene id: 89673:KIAA1191
uniprot id: A0A6J2MV46
uniprot id: A0A6J2MZQ5
uniprot id: A0A7E6CUK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P33MONOX family.
messages: Cytoplasm
messages: Interacts with NELFB, NOL12 and PRNP.
messages: Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth.

89673:LOC114500357
gene id: 89673:LOC114500357
uniprot id: A0A7E6E512
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Binds directly to 26S ribosomal RNA.

89673:GATAD2B
gene id: 89673:GATAD2B
uniprot id: A0A6J2KV10
uniprot id: A0A6J2L0D3
names: Subcellular Location Annotation
messages: Nucleus

89673:NPC1
gene id: 89673:NPC1
uniprot id: A0A7E6CEA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

89673:CANT1
gene id: 89673:CANT1
uniprot id: A0A6J2ME13
uniprot id: A0A7E6EGL3
names: Similarity
messages: Belongs to the apyrase family.

89673:STAM2
gene id: 89673:STAM2
uniprot id: A0A6J2LD05
uniprot id: A0A6J2LDZ9
uniprot id: A0A6J2LHT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Early endosome membrane
messages: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes.

89673:SPPL3
gene id: 89673:SPPL3
uniprot id: A0A6J2MW90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

89673:C1R
gene id: 89673:C1R
uniprot id: A0A6J2NAP7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:EPCAM
gene id: 89673:EPCAM
uniprot id: A0A6J2M0R8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPCAM family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lateral cell membrane
messages: May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.
messages: Membrane
messages: tight junction

89673:LOC114499077
gene id: 89673:LOC114499077
uniprot id: A0A6J2LU14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:FITM2
gene id: 89673:FITM2
uniprot id: A0A6J2MQB7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:CPA5
gene id: 89673:CPA5
uniprot id: A0A6J2MPY0
uniprot id: A0A6J2MPY7
names: Similarity
messages: Belongs to the peptidase M14 family.

89673:RORB
gene id: 89673:RORB
uniprot id: A0A7E6DF25
uniprot id: A0A7E6DF53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

89673:DNAL4
gene id: 89673:DNAL4
uniprot id: A0A6J2NFR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

89673:RRM2B
gene id: 89673:RRM2B
uniprot id: A0A6J2NCT7
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

89673:PROKR1
gene id: 89673:PROKR1
uniprot id: A0A6J2LXV5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:MICOS10
gene id: 89673:MICOS10
uniprot id: A0A6J2LLP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic10 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

89673:LOC114499991
gene id: 89673:LOC114499991
uniprot id: A0A6J2LYE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

89673:CAMTA1
gene id: 89673:CAMTA1
uniprot id: A0A7E6DQB8
names: Similarity
names: Subunit
messages: Belongs to the CAMTA family.
messages: May interact with calmodulin.

89673:PTP4A2
gene id: 89673:PTP4A2
uniprot id: A0A6J2LPP0
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

89673:DOP1B
gene id: 89673:DOP1B
uniprot id: A0A7E6D228
uniprot id: A0A7E6D4T7
names: Similarity
messages: Belongs to the dopey family.

89673:FAM83G
gene id: 89673:FAM83G
uniprot id: A0A7E6EBT1
names: Similarity
messages: Belongs to the FAM83 family.

89673:CEL
gene id: 89673:CEL
uniprot id: A0A6J2MSL5
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

89673:TNNT3
gene id: 89673:TNNT3
uniprot id: A0A6J2LU54
uniprot id: A0A6J2LV82
uniprot id: A0A6J2LZN9
uniprot id: A0A7E6E2K9
uniprot id: A0A7E6E345
uniprot id: A0A7E6E3C4
uniprot id: A0A7E6E423
uniprot id: A0A7E6E427
uniprot id: A0A7E6E447
uniprot id: A0A7E6E450
names: Function
names: Similarity
messages: Belongs to the troponin T family.
messages: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

89673:VWC2L
gene id: 89673:VWC2L
uniprot id: A0A6J2LGA6
names: Subcellular Location Annotation
messages: Synapse

89673:DNTTIP1
gene id: 89673:DNTTIP1
uniprot id: A0A6J2MKM2
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114500770
gene id: 89673:LOC114500770
uniprot id: A0A6J2M1C0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114499042
gene id: 89673:LOC114499042
uniprot id: A0A6J2LYA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TMEM165
gene id: 89673:TMEM165
uniprot id: A0A6J2LAI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

89673:GLB1L2
gene id: 89673:GLB1L2
uniprot id: A0A6J2N1W7
uniprot id: A0A7E6CUZ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

89673:PSPH
gene id: 89673:PSPH
uniprot id: A0A6J2LQP8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

89673:HP1BP3
gene id: 89673:HP1BP3
uniprot id: A0A7E6DRE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

89673:PLB1
gene id: 89673:PLB1
uniprot id: A0A7E6E478
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the 'GDSL' lipolytic enzyme family. Phospholipase B1 subfamily.
messages: Cell membrane
messages: Membrane

89673:HSPB7
gene id: 89673:HSPB7
uniprot id: A0A6J2LRD7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

89673:MALSU1
gene id: 89673:MALSU1
uniprot id: A0A6J2MUI6
names: Similarity
messages: Belongs to the Iojap/RsfS family.

89673:CADM4
gene id: 89673:CADM4
uniprot id: A0A6J2N0V2
names: Similarity
messages: Belongs to the nectin family.

89673:BZW2
gene id: 89673:BZW2
uniprot id: A0A6J2MTJ8
names: Similarity
messages: Belongs to the BZW family.

89673:RUVBL2
gene id: 89673:RUVBL2
uniprot id: A0A6J2N5R2
uniprot id: A0A7E6CN87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Dynein axonemal particle
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

89673:MCL1
gene id: 89673:MCL1
uniprot id: A0A6J2KT26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Cytoplasm
messages: Membrane
messages: nucleoplasm

89673:VSX1
gene id: 89673:VSX1
uniprot id: A0A6J2MN83
names: Subcellular Location Annotation
messages: Nucleus

89673:UNC45A
gene id: 89673:UNC45A
uniprot id: A0A7E6CMV6
names: Subcellular Location Annotation
messages: perinuclear region

89673:MINDY4B
gene id: 89673:MINDY4B
uniprot id: A0A6J2NCA7
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
messages: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

89673:LOC114513914
gene id: 89673:LOC114513914
uniprot id: A0A7E6DAU3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

89673:RRAGD
gene id: 89673:RRAGD
uniprot id: A0A6J2LE92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

89673:FZD6
gene id: 89673:FZD6
uniprot id: A0A6J2NB85
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:MTFR1
gene id: 89673:MTFR1
uniprot id: A0A6J2NCK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

89673:APOB
gene id: 89673:APOB
uniprot id: A0A7E6DWH6
uniprot id: A0A7E6DXH1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:RANBP10
gene id: 89673:RANBP10
uniprot id: A0A6J2KV51
uniprot id: A0A7E6CLZ0
names: Similarity
messages: Belongs to the RANBP9/10 family.

89673:EIF3M
gene id: 89673:EIF3M
uniprot id: A0A6J2LUL5
uniprot id: A0A6J2LYH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Belongs to the eIF-3 subunit M family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm

89673:LOC114509771
gene id: 89673:LOC114509771
uniprot id: A0A6J2MWY2
names: Similarity
messages: Belongs to the protein kinase superfamily.

89673:ROMO1
gene id: 89673:ROMO1
uniprot id: A0A6J2MKS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGR2 family.
messages: Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.
messages: Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation.
messages: Mitochondrion inner membrane

89673:SH3BGRL3
gene id: 89673:SH3BGRL3
uniprot id: A0A6J2LTT1
names: Similarity
messages: Belongs to the SH3BGR family.

89673:SH3RF1
gene id: 89673:SH3RF1
uniprot id: A0A6J2M7N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3RF family.
messages: lamellipodium
messages: perinuclear region
messages: trans-Golgi network

89673:LATS1
gene id: 89673:LATS1
uniprot id: A0A7E6DP62
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

89673:TNFRSF19
gene id: 89673:TNFRSF19
uniprot id: A0A7E6CJK3
uniprot id: A0A7E6CJN3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:SLC25A21
gene id: 89673:SLC25A21
uniprot id: A0A6J2L504
uniprot id: A0A7E6E0T2
uniprot id: A0A7E6E0U0
uniprot id: A0A7E6E1T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

89673:ITGB6
gene id: 89673:ITGB6
uniprot id: A0A6J2LLY3
uniprot id: A0A7E6DJX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

89673:DEFB124
gene id: 89673:DEFB124
uniprot id: A0A6J2MJ68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

89673:USP9X
gene id: 89673:USP9X
uniprot id: A0A6J2MML9
uniprot id: A0A7E6CZ29
uniprot id: A0A7E6D001
uniprot id: A0A7E6D1Q1
names: Similarity
messages: Belongs to the peptidase C19 family.

89673:TNRC6C
gene id: 89673:TNRC6C
uniprot id: A0A6J2ME14
uniprot id: A0A7E6EFB1
uniprot id: A0A7E6EFL5
names: Similarity
messages: Belongs to the GW182 family.

89673:RABGGTA
gene id: 89673:RABGGTA
uniprot id: A0A6J2LAB3
uniprot id: A0A7E6E422
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.
messages: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX, such as RAB1A, RAB3A, RAB5A and RAB7A.

89673:LOC114496555
gene id: 89673:LOC114496555
uniprot id: A0A6J2LPH0
uniprot id: A0A7E6DSL4
names: Similarity
messages: Belongs to the cytochrome P450 family.

89673:ATP6V0C
gene id: 89673:ATP6V0C
uniprot id: A0A6J2LHA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: Vacuole membrane
messages: clathrin-coated vesicle membrane
messages: synaptic vesicle membrane

89673:EGFL6
gene id: 89673:EGFL6
uniprot id: A0A6J2MMT6
uniprot id: A0A7E6D222
names: Caution
names: Similarity
messages: Belongs to the nephronectin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:OTOGL
gene id: 89673:OTOGL
uniprot id: A0A7E6D670
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:SLC5A8
gene id: 89673:SLC5A8
uniprot id: A0A6J2N9D7
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

89673:TOR1B
gene id: 89673:TOR1B
uniprot id: A0A6J2M5Z3
names: Similarity
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.

89673:HECTD3
gene id: 89673:HECTD3
uniprot id: A0A7E6DRN4
uniprot id: A0A7E6DSD7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC114505202
gene id: 89673:LOC114505202
uniprot id: A0A6J2MHV2
uniprot id: A0A6J2ML38
uniprot id: A0A6J2MLU6
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

89673:TRARG1
gene id: 89673:TRARG1
uniprot id: A0A7E6EC73
names: Similarity
messages: Belongs to the CD225/Dispanin family.

89673:LOC114505647
gene id: 89673:LOC114505647
uniprot id: A0A7E6D3B8
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

89673:B9D2
gene id: 89673:B9D2
uniprot id: A0A6J2N6B7
names: Subcellular Location Annotation
messages: cilium basal body

89673:DHX58
gene id: 89673:DHX58
uniprot id: A0A6J2MDG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

89673:LOC114503066
gene id: 89673:LOC114503066
uniprot id: A0A6J2MDR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ITGB8
gene id: 89673:ITGB8
uniprot id: A0A6J2MTJ1
uniprot id: A0A7E6CHR8
uniprot id: A0A7E6CHX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Melanosome
messages: Membrane
messages: Recycling endosome
messages: focal adhesion
messages: invadopodium membrane
messages: lamellipodium
messages: ruffle membrane

89673:GABRG2
gene id: 89673:GABRG2
uniprot id: A0A6J2MVM8
uniprot id: A0A6J2N0R5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRG2 sub-subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

89673:CPNE6
gene id: 89673:CPNE6
uniprot id: A0A7E6E3P5
names: Similarity
messages: Belongs to the copine family.

89673:GNG5
gene id: 89673:GNG5
uniprot id: A0A6J2LS70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

89673:NOC2L
gene id: 89673:NOC2L
uniprot id: A0A6J2LRN4
uniprot id: A0A7E6DPV8
uniprot id: A0A7E6DQE1
names: Similarity
messages: Belongs to the NOC2 family.

89673:LOC114511466
gene id: 89673:LOC114511466
uniprot id: A0A7E6CP09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IGFL family.
messages: Secreted

89673:NOC3L
gene id: 89673:NOC3L
uniprot id: A0A6J2LIU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF/MAK21 family.
messages: nucleolus

89673:ALX3
gene id: 89673:ALX3
uniprot id: A0A6J2KXB3
names: Subcellular Location Annotation
messages: Nucleus

89673:CACNG7
gene id: 89673:CACNG7
uniprot id: A0A6J2N233
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2.

89673:NXPH4
gene id: 89673:NXPH4
uniprot id: A0A6J2N7P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

89673:LOC114500555
gene id: 89673:LOC114500555
uniprot id: A0A6J2LZ92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114507122
gene id: 89673:LOC114507122
uniprot id: A0A6J2MN74
names: Subcellular Location Annotation
messages: Nucleus

89673:DKK3
gene id: 89673:DKK3
uniprot id: A0A6J2LVK4
uniprot id: A0A6J2LZH8
uniprot id: A0A7E6E0B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

89673:KRT78
gene id: 89673:KRT78
uniprot id: A0A6J2NEZ6
names: Similarity
messages: Belongs to the intermediate filament family.

89673:LOC114497930
gene id: 89673:LOC114497930
uniprot id: A0A6J2LQW3
uniprot id: A0A7E6DVI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX15/CtaA family.
messages: Membrane

89673:CHMP2A
gene id: 89673:CHMP2A
uniprot id: A0A6J2N387
names: Similarity
messages: Belongs to the SNF7 family.

89673:ATAT1
gene id: 89673:ATAT1
uniprot id: A0A6J2LDG6
uniprot id: A0A6J2LEN5
uniprot id: A0A6J2LEN9
uniprot id: A0A6J2LI85
uniprot id: A0A7E6DKL3
uniprot id: A0A7E6DKL8
uniprot id: A0A7E6DKM4
uniprot id: A0A7E6DKX6
uniprot id: A0A7E6DL02
uniprot id: A0A7E6DLA2
uniprot id: A0A7E6DLB0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Autoacetylation strongly increases tubulin acetylation.
messages: Belongs to the acetyltransferase ATAT1 family.
messages: Component of the BBSome complex. Interacts with AP2 alpha-adaptins, including AP2A2, but not with AP1 gamma-adaptin (AP1G1/AP1G2); this interaction is required for efficient alpha-tubulin acetylation, hence clathrin-coated pits are sites of microtubule acetylation.
messages: Cytoplasm
messages: Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. Required for normal sperm flagellar function. Promotes directional cell locomotion and chemotaxis, through AP2A2-dependent acetylation of alpha-tubulin at clathrin-coated pits that are concentrated at the leading edge of migrating cells. May facilitate primary cilium assembly.
messages: axon
messages: clathrin-coated pit
messages: cytoskeleton
messages: focal adhesion
messages: spindle

89673:AIDA
gene id: 89673:AIDA
uniprot id: A0A6J2NAK2
names: Similarity
messages: Belongs to the AIDA family.

89673:FASLG
gene id: 89673:FASLG
uniprot id: A0A6J2N4F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Cell membrane
messages: Cytoplasmic form induces gene transcription inhibition.
messages: Cytoplasmic vesicle lumen
messages: Lysosome lumen
messages: Nucleus
messages: Secreted

89673:SLC35F1
gene id: 89673:SLC35F1
uniprot id: A0A6J2LLX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

89673:LOC114488177
gene id: 89673:LOC114488177
uniprot id: A0A6J2KWI3
uniprot id: A0A7E6CLG9
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

89673:LOC114488824
gene id: 89673:LOC114488824
uniprot id: A0A6J2KSX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:RBFOX2
gene id: 89673:RBFOX2
uniprot id: A0A6J2N662
uniprot id: A0A7E6D822
uniprot id: A0A7E6D826
uniprot id: A0A7E6D832
uniprot id: A0A7E6D835
uniprot id: A0A7E6D837
uniprot id: A0A7E6D838
uniprot id: A0A7E6D840
uniprot id: A0A7E6D843
uniprot id: A0A7E6D847
uniprot id: A0A7E6D852
uniprot id: A0A7E6D856
uniprot id: A0A7E6D880
uniprot id: A0A7E6D885
uniprot id: A0A7E6D891
uniprot id: A0A7E6D895
uniprot id: A0A7E6D899
uniprot id: A0A7E6D8A4
uniprot id: A0A7E6D8U2
uniprot id: A0A7E6D8U7
uniprot id: A0A7E6D8V2
uniprot id: A0A7E6D8V9
uniprot id: A0A7E6D8W4
uniprot id: A0A7E6DB00
uniprot id: A0A7E6DB05
uniprot id: A0A7E6DB10
uniprot id: A0A7E6DB16
uniprot id: A0A7E6DB21
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

89673:HDAC1
gene id: 89673:HDAC1
uniprot id: A0A6J2LNC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

89673:AQP6
gene id: 89673:AQP6
uniprot id: A0A6J2N7T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

89673:ROPN1
gene id: 89673:ROPN1
uniprot id: A0A6J2L4Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ropporin family.
messages: flagellum

89673:MECP2
gene id: 89673:MECP2
uniprot id: A0A6J2MDT9
uniprot id: A0A6J2MFZ0
names: Function
names: Subcellular Location Annotation
messages: Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).
messages: Nucleus

89673:MLEC
gene id: 89673:MLEC
uniprot id: A0A6J2MUB6
uniprot id: A0A6J2MVX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the malectin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:PSMA8
gene id: 89673:PSMA8
uniprot id: A0A6J2MR81
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

89673:ZUP1
gene id: 89673:ZUP1
uniprot id: A0A7E6DNE5
names: Similarity
names: Subunit
messages: Belongs to the peptidase C78 family. ZUFSP subfamily.
messages: Interacts with RPA1 and RPA2.

89673:HSPG2
gene id: 89673:HSPG2
uniprot id: A0A7E6DQA1
uniprot id: A0A7E6DQA9
uniprot id: A0A7E6DQB6
uniprot id: A0A7E6DQC0
uniprot id: A0A7E6DQC5
uniprot id: A0A7E6DQZ4
uniprot id: A0A7E6DQZ9
uniprot id: A0A7E6DR06
uniprot id: A0A7E6DR26
uniprot id: A0A7E6DR31
uniprot id: A0A7E6DRG1
uniprot id: A0A7E6DRG8
uniprot id: A0A7E6DRH5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

89673:SEPTIN10
gene id: 89673:SEPTIN10
uniprot id: A0A6J2LLQ6
uniprot id: A0A7E6DTJ6
uniprot id: A0A7E6DTP5
uniprot id: A0A7E6DU65
uniprot id: A0A7E6DUT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

89673:SETD1B
gene id: 89673:SETD1B
uniprot id: A0A6J2MVC8
uniprot id: A0A7E6CTP8
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus speckle

89673:PIEZO2
gene id: 89673:PIEZO2
uniprot id: A0A7E6CDZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIEZO (TC 1.A.75) family.
messages: Membrane

89673:LOC114500440
gene id: 89673:LOC114500440
uniprot id: A0A6J2M0Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TUBB
gene id: 89673:TUBB
uniprot id: A0A6J2LA47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

89673:DLG2
gene id: 89673:DLG2
uniprot id: A0A6J2LQZ2
uniprot id: A0A7E6E373
uniprot id: A0A7E6E3S3
uniprot id: A0A7E6E3V7
uniprot id: A0A7E6E3V9
uniprot id: A0A7E6E4P7
uniprot id: A0A7E6E4U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: Membrane

89673:LOC114512870
gene id: 89673:LOC114512870
uniprot id: A0A6J2NC63
uniprot id: A0A6J2ND32
uniprot id: A0A6J2NEH8
uniprot id: A0A7E6D6G1
names: Similarity
messages: Belongs to the intermediate filament family.

89673:STEAP4
gene id: 89673:STEAP4
uniprot id: A0A6J2MQ48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

89673:EPHA3
gene id: 89673:EPHA3
uniprot id: A0A6J2KYK0
uniprot id: A0A7E6D482
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114502464
gene id: 89673:LOC114502464
uniprot id: A0A7E6DG68
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

89673:LOC114504857
gene id: 89673:LOC114504857
uniprot id: A0A7E6D0G7
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

89673:CD34
gene id: 89673:CD34
uniprot id: A0A6J2N9Z8
uniprot id: A0A7E6CV51
names: Subcellular Location Annotation
messages: Membrane

89673:SLC2A12
gene id: 89673:SLC2A12
uniprot id: A0A6J2LE66
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

89673:SNX4
gene id: 89673:SNX4
uniprot id: A0A6J2L0N5
names: Similarity
messages: Belongs to the sorting nexin family.

89673:SMU1
gene id: 89673:SMU1
uniprot id: A0A6J2LT39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SMU1 family.
messages: Nucleus speckle

89673:VGLL4
gene id: 89673:VGLL4
uniprot id: A0A6J2M1Y4
uniprot id: A0A6J2M7L6
uniprot id: A0A7E6E5T5
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

89673:ZFPM1
gene id: 89673:ZFPM1
uniprot id: A0A7E6CMW8
uniprot id: A0A7E6CN18
names: Subcellular Location Annotation
messages: Nucleus

89673:CCL1
gene id: 89673:CCL1
uniprot id: A0A6J2MD85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

89673:NUBP2
gene id: 89673:NUBP2
uniprot id: A0A6J2LMP4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
messages: Cytoplasm
messages: Heterotetramer of 2 NUBP1 and 2 NUBP2 chains. Interacts with KIFC1.
messages: Nucleus
messages: centrosome

89673:DNAH1
gene id: 89673:DNAH1
uniprot id: A0A7E6E592
uniprot id: A0A7E6E6S8
uniprot id: A0A7E6E6X9
names: Similarity
messages: Belongs to the dynein heavy chain family.

89673:APLP2
gene id: 89673:APLP2
uniprot id: A0A6J2MSM7
uniprot id: A0A6J2MYV5
uniprot id: A0A6J2MYW0
uniprot id: A0A6J2MZD0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:ETFDH
gene id: 89673:ETFDH
uniprot id: A0A6J2MCP4
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

89673:LOC114510639
gene id: 89673:LOC114510639
uniprot id: A0A7E6CSS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:TRMT11
gene id: 89673:TRMT11
uniprot id: A0A6J2LLL6
uniprot id: A0A7E6DN19
uniprot id: A0A7E6DN43
uniprot id: A0A7E6DNQ1
uniprot id: A0A7E6DP01
names: Function
names: Subunit
messages: Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.
messages: Interacts with TRMT112.

89673:RPS26
gene id: 89673:RPS26
uniprot id: A0A6J2NCX2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

89673:MTURN
gene id: 89673:MTURN
uniprot id: A0A6J2MVS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTURN family.
messages: Cytoplasm

89673:ELOVL4
gene id: 89673:ELOVL4
uniprot id: A0A6J2LKN4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ELO family. ELOVL4 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May play a critical role in early brain and skin development.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Oligomer.
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

89673:LOC114510840
gene id: 89673:LOC114510840
uniprot id: A0A6J2MY62
uniprot id: A0A7E6CQI5
names: Similarity
messages: Belongs to the MHC class I family.

89673:OCM2
gene id: 89673:OCM2
uniprot id: A0A6J2N3V7
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

89673:LOC114506663
gene id: 89673:LOC114506663
uniprot id: A0A6J2MQJ4
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

89673:TCTN1
gene id: 89673:TCTN1
uniprot id: A0A7E6CUA6
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

89673:HOXC13
gene id: 89673:HOXC13
uniprot id: A0A6J2N822
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

89673:BZW1
gene id: 89673:BZW1
uniprot id: A0A6J2LII0
uniprot id: A0A6J2LL14
names: Similarity
messages: Belongs to the BZW family.

89673:ZKSCAN1
gene id: 89673:ZKSCAN1
uniprot id: A0A6J2L8G8
uniprot id: A0A6J2L9Q6
uniprot id: A0A6J2L9V2
uniprot id: A0A7E6D966
names: Subcellular Location Annotation
messages: Nucleus

89673:HMCN1
gene id: 89673:HMCN1
uniprot id: A0A6J2N8Z8
uniprot id: A0A7E6CVX4
uniprot id: A0A7E6CW16
uniprot id: A0A7E6CWE4
uniprot id: A0A7E6CYN1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:EMP1
gene id: 89673:EMP1
uniprot id: A0A6J2NFE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

89673:ADAM17
gene id: 89673:ADAM17
uniprot id: A0A6J2LTT0
uniprot id: A0A6J2LUY7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:SLC16A5
gene id: 89673:SLC16A5
uniprot id: A0A6J2MC23
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114494503
gene id: 89673:LOC114494503
uniprot id: A0A6J2LDJ0
uniprot id: A0A6J2LHC5
uniprot id: A0A7E6DJK6
uniprot id: A0A7E6DJT6
uniprot id: A0A7E6DJU5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

89673:SNRNP27
gene id: 89673:SNRNP27
uniprot id: A0A6J2KXA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNUT3 family.
messages: May play a role in mRNA splicing.
messages: Nucleus
messages: Part of a tri-snRNP complex.

89673:ENTPD6
gene id: 89673:ENTPD6
uniprot id: A0A7E6CEB3
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

89673:HIP1
gene id: 89673:HIP1
uniprot id: A0A6J2L8S2
uniprot id: A0A6J2LBK4
uniprot id: A0A7E6DBF1
uniprot id: A0A7E6DBZ5
names: Similarity
messages: Belongs to the SLA2 family.

89673:ARMCX1
gene id: 89673:ARMCX1
uniprot id: A0A6J2MK04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eutherian X-chromosome-specific Armcx family.
messages: Membrane

89673:VAMP8
gene id: 89673:VAMP8
uniprot id: A0A6J2LY07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

89673:LOC114509465
gene id: 89673:LOC114509465
uniprot id: A0A6J2N064
names: Similarity
messages: Belongs to the GST superfamily. Theta family.

89673:UPP2
gene id: 89673:UPP2
uniprot id: A0A6J2LKT2
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

89673:FBXL5
gene id: 89673:FBXL5
uniprot id: A0A6J2L241
uniprot id: A0A7E6D6A4
names: Subcellular Location Annotation
messages: perinuclear region

89673:SEC61B
gene id: 89673:SEC61B
uniprot id: A0A6J2M9B0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC61-beta family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Necessary for protein translocation in the endoplasmic reticulum.

89673:SPTLC3
gene id: 89673:SPTLC3
uniprot id: A0A6J2MQX6
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

89673:LOC114504669
gene id: 89673:LOC114504669
uniprot id: A0A6J2MJD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

89673:LOC114489530
gene id: 89673:LOC114489530
uniprot id: A0A6J2KWT5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:HS3ST3B1
gene id: 89673:HS3ST3B1
uniprot id: A0A6J2NCT3
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

89673:MET
gene id: 89673:MET
uniprot id: A0A6J2MTI3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:GRHL2
gene id: 89673:GRHL2
uniprot id: A0A6J2NB45
uniprot id: A0A7E6E6K3
uniprot id: A0A7E6E7E9
names: Subcellular Location Annotation
messages: Nucleus

89673:CNN1
gene id: 89673:CNN1
uniprot id: A0A6J2MAM0
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

89673:SKA1
gene id: 89673:SKA1
uniprot id: A0A7E6CH43
names: Similarity
messages: Belongs to the SKA1 family.

89673:RPRD1A
gene id: 89673:RPRD1A
uniprot id: A0A6J2MS65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the RNA polymerase II complex.
messages: Belongs to the UPF0400 (RTT103) family.
messages: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle.
messages: Nucleus

89673:PHACTR2
gene id: 89673:PHACTR2
uniprot id: A0A7E6DNH4
uniprot id: A0A7E6DNH9
uniprot id: A0A7E6DNJ2
uniprot id: A0A7E6DNJ4
uniprot id: A0A7E6DNZ2
uniprot id: A0A7E6DNZ9
uniprot id: A0A7E6DP68
uniprot id: A0A7E6DPH3
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

89673:SPAST
gene id: 89673:SPAST
uniprot id: A0A6J2LU87
uniprot id: A0A6J2LWB6
uniprot id: A0A6J2LZ72
uniprot id: A0A6J2LZT6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. It is critical for the biogenesis and maintenance of complex microtubule arrays in axons, spindles and cilia. SPAST is involved in abscission step of cytokinesis and nuclear envelope reassembly during anaphase in cooperation with the ESCRT-III complex. Recruited at the midbody, probably by IST1, and participates in membrane fission during abscission together with the ESCRT-III complex. Recruited to the nuclear membrane by IST1 and mediates microtubule severing, promoting nuclear envelope sealing and mitotic spindle disassembly during late anaphase. Required for membrane traffic from the endoplasmic reticulum (ER) to the Golgi and endosome recycling. Recruited by IST1 to endosomes and regulates early endosomal tubulation and recycling by mediating microtubule severing. Probably plays a role in axon growth and the formation of axonal branches.
messages: Allosteric enzyme with a cooperative mechanism; at least two neighbor subunits influence each other strongly in spastin hexamers. Microtubule binding promotes cooperative interactions among spastin subunits.
messages: Belongs to the AAA ATPase family. Spastin subfamily.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Homohexamer. Mostly monomeric, but assembles into hexameric structure for short periods of time. Oligomerization seems to be a prerequisite for catalytic activity. Binding to ATP in a cleft between two adjacent subunits stabilizes the homohexameric form. Binds to microtubules at least in part via the alpha-tubulin and beta-tubulin tails. The hexamer adopts a ring conformation through which microtubules pass prior to being severed. Does not interact strongly with tubulin heterodimers. Interacts (via MIT domain) with CHMP1B; the interaction is direct. Interacts with SSNA1. Interacts with ATL1. Interacts with RTN1. Interacts with ZFYVE27. Interacts with REEP1. Interacts (via MIT domain) with IST1.
messages: Membrane
messages: Midbody
messages: Nucleus
messages: axon
messages: centrosome
messages: cytoskeleton
messages: perinuclear region
messages: spindle

89673:SLX4
gene id: 89673:SLX4
uniprot id: A0A7E6D968
names: Similarity
messages: Belongs to the SLX4 family.

89673:PSMB4
gene id: 89673:PSMB4
uniprot id: A0A6J2KUI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1B family.
messages: Cytoplasm
messages: Non-catalytic component of the proteasome.
messages: Nucleus

89673:LOC114506497
gene id: 89673:LOC114506497
uniprot id: A0A6J2MPT2
names: Subcellular Location Annotation
messages: Nucleus

89673:SH3BGRL
gene id: 89673:SH3BGRL
uniprot id: A0A6J2MGC7
names: Similarity
messages: Belongs to the SH3BGR family.

89673:ST6GAL1
gene id: 89673:ST6GAL1
uniprot id: A0A7E6D348
uniprot id: A0A7E6D353
uniprot id: A0A7E6D388
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

89673:LOC114501366
gene id: 89673:LOC114501366
uniprot id: A0A7E6E852
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

89673:NTSR1
gene id: 89673:NTSR1
uniprot id: A0A6J2MN34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

89673:ADCY9
gene id: 89673:ADCY9
uniprot id: A0A6J2MN24
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

89673:APOE
gene id: 89673:APOE
uniprot id: A0A6J2N7D0
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

89673:POLD2
gene id: 89673:POLD2
uniprot id: A0A6J2KX13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase delta/II small subunit family.
messages: Nucleus

89673:TMEM150B
gene id: 89673:TMEM150B
uniprot id: A0A6J2MXX9
names: Subcellular Location Annotation
messages: Membrane

89673:ITGB5
gene id: 89673:ITGB5
uniprot id: A0A6J2L248
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

89673:HNMT
gene id: 89673:HNMT
uniprot id: A0A6J2LDX7
uniprot id: A0A7E6DKM0
names: Function
names: Subunit
messages: Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine.
messages: Monomer.

89673:METTL8
gene id: 89673:METTL8
uniprot id: A0A6J2LHP2
uniprot id: A0A7E6DJE8
uniprot id: A0A7E6DJM6
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

89673:ERN2
gene id: 89673:ERN2
uniprot id: A0A7E6DAJ9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:SNX1
gene id: 89673:SNX1
uniprot id: A0A6J2L405
uniprot id: A0A7E6CDY9
uniprot id: A0A7E6CFL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: lamellipodium
messages: trans-Golgi network membrane

89673:TRHDE
gene id: 89673:TRHDE
uniprot id: A0A6J2NDF1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Membrane

89673:LOC114503202
gene id: 89673:LOC114503202
uniprot id: A0A6J2MAQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM98 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: extracellular exosome

89673:STXBP1
gene id: 89673:STXBP1
uniprot id: A0A6J2MN27
uniprot id: A0A6J2MSK5
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

89673:PWWP3A
gene id: 89673:PWWP3A
uniprot id: A0A6J2MCA6
uniprot id: A0A7E6E8M7
uniprot id: A0A7E6EAN8
names: Similarity
messages: Belongs to the PWWP3A family.

89673:LOC114511734
gene id: 89673:LOC114511734
uniprot id: A0A7E6CNF7
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114494188
gene id: 89673:LOC114494188
uniprot id: A0A6J2LFQ7
names: Similarity
names: Subunit
messages: Belongs to the peptidase M18 family.
messages: Tetrahedron-shaped homododecamer built from six homodimers.

89673:CALB2
gene id: 89673:CALB2
uniprot id: A0A6J2KSP7
names: Function
names: Similarity
messages: Belongs to the calbindin family.
messages: Calretinin is a calcium-binding protein which is abundant in auditory neurons.

89673:YWHAQ
gene id: 89673:YWHAQ
uniprot id: A0A6J2LYV1
names: Function
names: Similarity
messages: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.
messages: Belongs to the 14-3-3 family.

89673:FAM229A
gene id: 89673:FAM229A
uniprot id: A0A6J2LU72
names: Similarity
messages: Belongs to the FAM229 family.

89673:RPS23
gene id: 89673:RPS23
uniprot id: A0A6J2LRV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Rough endoplasmic reticulum

89673:CHADL
gene id: 89673:CHADL
uniprot id: A0A7E6DBC2
names: Similarity
messages: Belongs to the Toll-like receptor family.

89673:TIMM22
gene id: 89673:TIMM22
uniprot id: A0A6J2ME56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM22 complex.
messages: Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.
messages: Membrane
messages: Mitochondrion inner membrane

89673:ATG13
gene id: 89673:ATG13
uniprot id: A0A6J2LU69
uniprot id: A0A6J2LW97
uniprot id: A0A6J2LZ54
uniprot id: A0A6J2LZS1
uniprot id: A0A7E6E1Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.
messages: Belongs to the ATG13 family. Metazoan subfamily.
messages: Preautophagosomal structure

89673:TMEM63C
gene id: 89673:TMEM63C
uniprot id: A0A7E6CNT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

89673:CDKN1C
gene id: 89673:CDKN1C
uniprot id: A0A6J2LZR7
uniprot id: A0A7E6E3Z5
names: Similarity
messages: Belongs to the CDI family.

89673:SH3BGR
gene id: 89673:SH3BGR
uniprot id: A0A6J2L082
names: Similarity
messages: Belongs to the SH3BGR family.

89673:ZWILCH
gene id: 89673:ZWILCH
uniprot id: A0A7E6CEI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZWILCH family.
messages: Component of the RZZ complex.
messages: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex.
messages: kinetochore

89673:LOC114500474
gene id: 89673:LOC114500474
uniprot id: A0A6J2LZ08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:TNMD
gene id: 89673:TNMD
uniprot id: A0A6J2MLM5
names: Similarity
messages: Belongs to the chondromodulin-1 family.

89673:LOC118499239
gene id: 89673:LOC118499239
uniprot id: A0A7E6D915
uniprot id: A0A7E6D981
uniprot id: A0A7E6D9X3
names: Similarity
messages: Belongs to the MHC class I family.

89673:SEMA4D
gene id: 89673:SEMA4D
uniprot id: A0A6J2NBF2
uniprot id: A0A7E6DE77
uniprot id: A0A7E6DE87
uniprot id: A0A7E6DE91
uniprot id: A0A7E6DEA2
uniprot id: A0A7E6DEA9
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:FRK
gene id: 89673:FRK
uniprot id: A0A6J2LF54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

89673:TANGO6
gene id: 89673:TANGO6
uniprot id: A0A6J2NJZ1
names: Similarity
messages: Belongs to the Tango6 family.

89673:LOC114512605
gene id: 89673:LOC114512605
uniprot id: A0A6J2N6A1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:FSCN2
gene id: 89673:FSCN2
uniprot id: A0A6J2MGS2
uniprot id: A0A7E6EEX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

89673:SPTSSA
gene id: 89673:SPTSSA
uniprot id: A0A6J2L8N7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:LOC114507012
gene id: 89673:LOC114507012
uniprot id: A0A7E6CGS4
names: Similarity
messages: Belongs to the TCTP family.

89673:GPR83
gene id: 89673:GPR83
uniprot id: A0A6J2M1S6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:GUK1
gene id: 89673:GUK1
uniprot id: A0A6J2NEY9
uniprot id: A0A7E6EBJ1
uniprot id: A0A7E6ECK7
names: Similarity
messages: Belongs to the guanylate kinase family.

89673:ZDHHC3
gene id: 89673:ZDHHC3
uniprot id: A0A6J2M1U4
uniprot id: A0A6J2M435
uniprot id: A0A7E6E4S9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

89673:LOC114495584
gene id: 89673:LOC114495584
uniprot id: A0A6J2LKX3
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

89673:TGFB1I1
gene id: 89673:TGFB1I1
uniprot id: A0A6J2LJ38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paxillin family.
messages: cytoskeleton
messages: focal adhesion

89673:ORC5
gene id: 89673:ORC5
uniprot id: A0A6J2MPK3
uniprot id: A0A7E6CI32
uniprot id: A0A7E6CID1
uniprot id: A0A7E6CIH3
names: Subcellular Location Annotation
messages: Nucleus

89673:HIGD1A
gene id: 89673:HIGD1A
uniprot id: A0A6J2M2Y5
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

89673:NADK
gene id: 89673:NADK
uniprot id: A0A6J2LN30
names: Similarity
messages: Belongs to the NAD kinase family.

89673:PLA2G12A
gene id: 89673:PLA2G12A
uniprot id: A0A6J2L8K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Secreted

89673:MRI1
gene id: 89673:MRI1
uniprot id: A0A6J2MH72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
messages: Cytoplasm
messages: Nucleus

89673:ARL3
gene id: 89673:ARL3
uniprot id: A0A6J2LP89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

89673:LOC114489136
gene id: 89673:LOC114489136
uniprot id: A0A7E6CW42
names: Similarity
messages: Belongs to the histone H3 family.

89673:ADCY6
gene id: 89673:ADCY6
uniprot id: A0A7E6D9S2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

89673:HSPA5
gene id: 89673:HSPA5
uniprot id: A0A6J2N7C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: Cell surface
messages: Endoplasmic reticulum lumen
messages: Melanosome

89673:CACNG1
gene id: 89673:CACNG1
uniprot id: A0A6J2MCV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either CACNB1 or CACNB2.
messages: Membrane
messages: Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
messages: sarcolemma

89673:IL17RA
gene id: 89673:IL17RA
uniprot id: A0A6J2MRK7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

89673:LOC114513407
gene id: 89673:LOC114513407
uniprot id: A0A6J2N9C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:HSPB8
gene id: 89673:HSPB8
uniprot id: A0A6J2MU89
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

89673:FGF18
gene id: 89673:FGF18
uniprot id: A0A6J2N1M7
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

89673:NOP53
gene id: 89673:NOP53
uniprot id: A0A6J2MZM8
uniprot id: A0A6J2N602
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP53 family.
messages: nucleolus
messages: nucleoplasm

89673:LOC114505634
gene id: 89673:LOC114505634
uniprot id: A0A7E6D0P2
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

89673:LOC114503923
gene id: 89673:LOC114503923
uniprot id: A0A6J2MDB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC118500486
gene id: 89673:LOC118500486
uniprot id: A0A7E6DP80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. As part of the U7 snRNP it is involved in histone 3'-end processing.
messages: cytosol

89673:SENP2
gene id: 89673:SENP2
uniprot id: A0A6J2L2N1
uniprot id: A0A6J2L4M2
uniprot id: A0A7E6D330
uniprot id: A0A7E6D364
uniprot id: A0A7E6D5X8
names: Similarity
messages: Belongs to the peptidase C48 family.

89673:TNRC6A
gene id: 89673:TNRC6A
uniprot id: A0A7E6DE15
names: Similarity
messages: Belongs to the GW182 family.

89673:LOC114500681
gene id: 89673:LOC114500681
uniprot id: A0A6J2M1T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:LOC114503560
gene id: 89673:LOC114503560
uniprot id: A0A6J2MFX0
uniprot id: A0A7E6EFY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

89673:ATG9A
gene id: 89673:ATG9A
uniprot id: A0A6J2LF41
uniprot id: A0A7E6DID1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

89673:LOC114489389
gene id: 89673:LOC114489389
uniprot id: A0A6J2KWT5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:GPATCH11
gene id: 89673:GPATCH11
uniprot id: A0A6J2LW01
uniprot id: A0A7E6DXJ3
names: Similarity
messages: Belongs to the GPATCH11 family.

89673:PIK3IP1
gene id: 89673:PIK3IP1
uniprot id: A0A6J2MY22
uniprot id: A0A6J2N2L3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LOC118500231
gene id: 89673:LOC118500231
uniprot id: A0A7E6DMM7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:BBOX1
gene id: 89673:BBOX1
uniprot id: A0A6J2M3M0
names: Function
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.
messages: Catalyzes the formation of L-carnitine from gamma-butyrobetaine.

89673:METTL2A
gene id: 89673:METTL2A
uniprot id: A0A6J2M884
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

89673:LOC114510216
gene id: 89673:LOC114510216
uniprot id: A0A6J2N383
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:HS3ST4
gene id: 89673:HS3ST4
uniprot id: A0A6J2MY63
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

89673:ENKUR
gene id: 89673:ENKUR
uniprot id: A0A6J2L8J3
names: Subcellular Location Annotation
messages: cilium axoneme

89673:LOC114514555
gene id: 89673:LOC114514555
uniprot id: A0A6J2NCM4
names: Similarity
messages: Belongs to the neutral sphingomyelinase family.

89673:SLC7A10
gene id: 89673:SLC7A10
uniprot id: A0A6J2N628
names: Subcellular Location Annotation
messages: Membrane

89673:MCM10
gene id: 89673:MCM10
uniprot id: A0A6J2L8V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM10 family.
messages: Nucleus

89673:FCHO2
gene id: 89673:FCHO2
uniprot id: A0A6J2LJ35
uniprot id: A0A7E6DAC6
uniprot id: A0A7E6DAG1
uniprot id: A0A7E6DAQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FCHO family.
messages: clathrin-coated pit

89673:ELF5
gene id: 89673:ELF5
uniprot id: A0A6J2LRW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

89673:CATSPERD
gene id: 89673:CATSPERD
uniprot id: A0A6J2MEF6
names: Similarity
messages: Belongs to the CATSPERD family.

89673:MYH14
gene id: 89673:MYH14
uniprot id: A0A7E6CNH4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

89673:DNASE1
gene id: 89673:DNASE1
uniprot id: A0A6J2LI53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNase I family.
messages: Nucleus envelope
messages: Zymogen granule

89673:PRND
gene id: 89673:PRND
uniprot id: A0A6J2MK92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prion family.
messages: Cell membrane
messages: Membrane

89673:FAM133B
gene id: 89673:FAM133B
uniprot id: A0A6J2MMF0
names: Similarity
messages: Belongs to the FAM133 family.

89673:DKKL1
gene id: 89673:DKKL1
uniprot id: A0A6J2N6Z0
names: Subcellular Location Annotation
messages: Secreted

89673:FN1
gene id: 89673:FN1
uniprot id: A0A6J2LG16
uniprot id: A0A6J2LG26
uniprot id: A0A6J2LH80
uniprot id: A0A6J2LIF6
uniprot id: A0A6J2LKX8
uniprot id: A0A6J2LKY3
uniprot id: A0A6J2LKZ4
uniprot id: A0A6J2LLN9
uniprot id: A0A6J2LLP8
uniprot id: A0A6J2LLQ2
uniprot id: A0A7E6DIE9
uniprot id: A0A7E6DIJ1
names: Function
messages: Secreted by contracting muscle, induces liver autophagy, a degradative pathway for nutrient mobilization and damage removal, and systemic insulin sensitization via hepatic ITGA5:ITGB1 integrin receptor signaling.

89673:ACSS1
gene id: 89673:ACSS1
uniprot id: A0A7E6CEF5
uniprot id: A0A7E6CEZ0
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

89673:PTN
gene id: 89673:PTN
uniprot id: A0A6J2MTF6
names: Similarity
messages: Belongs to the pleiotrophin family.

89673:FAM3C
gene id: 89673:FAM3C
uniprot id: A0A6J2MMU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

89673:KANSL2
gene id: 89673:KANSL2
uniprot id: A0A6J2NE14
uniprot id: A0A7E6D710
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.
messages: Component of the NSL complex at least composed of MOF/KAT8, KANSL1, KANSL2, KANSL3, MCRS1, PHF20, OGT1/OGT, WDR5 and HCFC1.
messages: Nucleus

89673:GALNT9
gene id: 89673:GALNT9
uniprot id: A0A6J2KW23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

89673:LOC114489536
gene id: 89673:LOC114489536
uniprot id: A0A6J2L0Q6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:SLC16A13
gene id: 89673:SLC16A13
uniprot id: A0A6J2NJE5
uniprot id: A0A7E6ECF3
uniprot id: A0A7E6EDK1
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114513359
gene id: 89673:LOC114513359
uniprot id: A0A6J2N7D3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CEP162
gene id: 89673:CEP162
uniprot id: A0A6J2LHY7
uniprot id: A0A7E6DMZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP162 family.
messages: centriole

89673:DDX31
gene id: 89673:DDX31
uniprot id: A0A6J2N3J3
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

89673:AR
gene id: 89673:AR
uniprot id: A0A6J2MHN5
names: Similarity
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.

89673:CD99L2
gene id: 89673:CD99L2
uniprot id: A0A6J2MGQ1
uniprot id: A0A6J2MJY8
names: Similarity
messages: Belongs to the CD99 family.

89673:CRB2
gene id: 89673:CRB2
uniprot id: A0A6J2LYS2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:WLS
gene id: 89673:WLS
uniprot id: A0A6J2LJW4
uniprot id: A0A7E6DSH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the wntless family.
messages: Golgi apparatus membrane
messages: Membrane

89673:LOC114511071
gene id: 89673:LOC114511071
uniprot id: A0A6J2N0Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMN family.
messages: Cajal body
messages: Perikaryon
messages: Z line
messages: gem
messages: neuron projection

89673:PDHX
gene id: 89673:PDHX
uniprot id: A0A6J2LVB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Mitochondrion matrix

89673:ATP5F1B
gene id: 89673:ATP5F1B
uniprot id: A0A6J2N715
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

89673:NRG3
gene id: 89673:NRG3
uniprot id: A0A6J2LRR9
uniprot id: A0A6J2LVN7
uniprot id: A0A7E6DUF5
names: Caution
names: Similarity
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:UGT8
gene id: 89673:UGT8
uniprot id: A0A6J2M8L9
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

89673:DCLK1
gene id: 89673:DCLK1
uniprot id: A0A6J2MS06
uniprot id: A0A7E6CJJ0
uniprot id: A0A7E6CJP4
uniprot id: A0A7E6CLM0
names: Similarity
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

89673:IAH1
gene id: 89673:IAH1
uniprot id: A0A6J2LZF5
names: Function
names: Similarity
messages: Belongs to the 'GDSL' lipolytic enzyme family. IAH1 subfamily.
messages: Probable lipase.

89673:MELTF
gene id: 89673:MELTF
uniprot id: A0A7E6D4H6
uniprot id: A0A7E6D568
names: Similarity
messages: Belongs to the transferrin family.

89673:MRPL28
gene id: 89673:MRPL28
uniprot id: A0A6J2LPA7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

89673:PSMA2
gene id: 89673:PSMA2
uniprot id: A0A6J2MNT8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

89673:DDX53
gene id: 89673:DDX53
uniprot id: A0A6J2MIR4
names: Similarity
messages: Belongs to the DEAD box helicase family.

89673:SPOPL
gene id: 89673:SPOPL
uniprot id: A0A6J2LC92
names: Similarity
messages: Belongs to the Tdpoz family.

89673:LOC114497007
gene id: 89673:LOC114497007
uniprot id: A0A7E6DX11
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:C13H22orf39
gene id: 89673:C13H22orf39
uniprot id: A0A6J2N1Q0
names: Similarity
messages: Belongs to the UPF0545 family.

89673:LOC118497651
gene id: 89673:LOC118497651
uniprot id: A0A7E6CP58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lambda interferon family.
messages: Secreted

89673:CDCA7L
gene id: 89673:CDCA7L
uniprot id: A0A7E6CJJ2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

89673:ATP2A1
gene id: 89673:ATP2A1
uniprot id: A0A6J2L5Y4
uniprot id: A0A7E6DD08
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

89673:SCG3
gene id: 89673:SCG3
uniprot id: A0A6J2L8P6
names: Subcellular Location Annotation
messages: Membrane
messages: Secreted
messages: secretory vesicle membrane

89673:HSD17B8
gene id: 89673:HSD17B8
uniprot id: A0A7E6DL17
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

89673:MMP21
gene id: 89673:MMP21
uniprot id: A0A6J2LL49
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

89673:MASP2
gene id: 89673:MASP2
uniprot id: A0A6J2LN58
uniprot id: A0A7E6DQJ4
uniprot id: A0A7E6DQY8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:SEC23A
gene id: 89673:SEC23A
uniprot id: A0A6J2L2Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

89673:RNF167
gene id: 89673:RNF167
uniprot id: A0A6J2NBS3
names: Subcellular Location Annotation
messages: Membrane

89673:SIDT1
gene id: 89673:SIDT1
uniprot id: A0A6J2KZY3
uniprot id: A0A6J2L0K1
uniprot id: A0A7E6D466
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SID1 family.
messages: Membrane

89673:LOC114498953
gene id: 89673:LOC114498953
uniprot id: A0A6J2LUP3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:APOA2
gene id: 89673:APOA2
uniprot id: A0A6J2L153
uniprot id: A0A7E6CWK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apolipoprotein A2 family.
messages: Secreted

89673:GRM1
gene id: 89673:GRM1
uniprot id: A0A6J2LF88
uniprot id: A0A6J2LGI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

89673:SPIB
gene id: 89673:SPIB
uniprot id: A0A6J2MZL7
uniprot id: A0A6J2N1B3
uniprot id: A0A6J2N5Z4
uniprot id: A0A7E6CNH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

89673:SLC25A51
gene id: 89673:SLC25A51
uniprot id: A0A6J2MWA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

89673:MTMR8
gene id: 89673:MTMR8
uniprot id: A0A6J2MH73
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

89673:IMMP1L
gene id: 89673:IMMP1L
uniprot id: A0A6J2M1T0
uniprot id: A0A7E6E134
uniprot id: A0A7E6E1A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26 family.
messages: Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO.
messages: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
messages: Mitochondrion inner membrane

89673:C4BPB
gene id: 89673:C4BPB
uniprot id: A0A6J2N1T2
uniprot id: A0A7E6CWD4
uniprot id: A0A7E6CWQ3
uniprot id: A0A7E6CX34
uniprot id: A0A7E6CYY5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:FEV
gene id: 89673:FEV
uniprot id: A0A6J2LGH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

89673:SDR42E2
gene id: 89673:SDR42E2
uniprot id: A0A7E6DE54
names: Similarity
messages: Belongs to the 3-beta-HSD family.

89673:LOC114489390
gene id: 89673:LOC114489390
uniprot id: A0A6J2KWT5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

89673:LOC114488626
gene id: 89673:LOC114488626
uniprot id: A0A6J2KU54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

89673:BTBD10
gene id: 89673:BTBD10
uniprot id: A0A6J2LQY2
uniprot id: A0A6J2LQY7
uniprot id: A0A6J2LT15
names: Subcellular Location Annotation
messages: Cytoplasm

89673:CLDN10
gene id: 89673:CLDN10
uniprot id: A0A6J2MSI1
uniprot id: A0A6J2MX13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

89673:COQ10A
gene id: 89673:COQ10A
uniprot id: A0A6J2N4H7
uniprot id: A0A6J2N6A9
uniprot id: A0A7E6D647
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

89673:CENPBD1
gene id: 89673:CENPBD1
uniprot id: A0A7E6CQQ8
names: Similarity
messages: Belongs to the tigger transposable element derived protein family.

89673:LOC114503964
gene id: 89673:LOC114503964
uniprot id: A0A6J2MDG7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:NKX6-1
gene id: 89673:NKX6-1
uniprot id: A0A6J2L8Q4
names: Subcellular Location Annotation
messages: Nucleus

89673:LOC114509084
gene id: 89673:LOC114509084
uniprot id: A0A6J2MS17
uniprot id: A0A6J2MTR4
uniprot id: A0A6J2MYA7
uniprot id: A0A6J2MYR0
uniprot id: A0A7E6CRL6
uniprot id: A0A7E6CRM4
uniprot id: A0A7E6CRY5
uniprot id: A0A7E6CS61
uniprot id: A0A7E6CU96
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

89673:OSBP2
gene id: 89673:OSBP2
uniprot id: A0A6J2MVQ4
uniprot id: A0A6J2MXC6
uniprot id: A0A6J2MXD7
uniprot id: A0A6J2N2K4
uniprot id: A0A7E6CTH9
uniprot id: A0A7E6CWB7
names: Similarity
messages: Belongs to the OSBP family.

89673:CPSF4
gene id: 89673:CPSF4
uniprot id: A0A6J2N4L6
uniprot id: A0A6J2N4M7
uniprot id: A0A6J2N978
uniprot id: A0A7E6DBC9
uniprot id: A0A7E6DCF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex.
messages: Nucleus

89673:LOC114505971
gene id: 89673:LOC114505971
uniprot id: A0A6J2MML5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL15 family.
messages: Cytoplasm

89673:LOC114489384
gene id: 89673:LOC114489384
uniprot id: A0A6J2KUR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

89673:LOC114491038
gene id: 89673:LOC114491038
uniprot id: A0A7E6DEG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:CHFR
gene id: 89673:CHFR
uniprot id: A0A6J2L1F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CHFR family.
messages: PML body

89673:KDSR
gene id: 89673:KDSR
uniprot id: A0A6J2MLA7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

89673:ALG6
gene id: 89673:ALG6
uniprot id: A0A6J2LPU3
uniprot id: A0A7E6DSH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

89673:CASP14
gene id: 89673:CASP14
uniprot id: A0A6J2M4A5
names: Similarity
messages: Belongs to the peptidase C14A family.

89673:LOC114491861
gene id: 89673:LOC114491861
uniprot id: A0A7E6DDY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Membrane

89673:LOC114509133
gene id: 89673:LOC114509133
uniprot id: A0A6J2MZ47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:ADAMTS15
gene id: 89673:ADAMTS15
uniprot id: A0A6J2N3N4
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

89673:LOC114510145
gene id: 89673:LOC114510145
uniprot id: A0A7E6CUC1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

89673:FIS1
gene id: 89673:FIS1
uniprot id: A0A6J2MYI6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIS1 family.
messages: Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.
messages: Membrane
messages: Mitochondrion outer membrane
messages: The C-terminus is required for mitochondrial localization, while the N-terminus is necessary for mitochondrial fission.

89673:GRWD1
gene id: 89673:GRWD1
uniprot id: A0A6J2N0R9
names: Subcellular Location Annotation
messages: Nucleus

89673:TMEM107
gene id: 89673:TMEM107
uniprot id: A0A6J2NJ19
names: Subcellular Location Annotation
messages: Membrane

89673:FIBIN
gene id: 89673:FIBIN
uniprot id: A0A6J2M183
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FIBIN family.
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer; disulfide-linked. Seems to also exist as monomers.
messages: Secreted

89673:TMEM45A
gene id: 89673:TMEM45A
uniprot id: A0A6J2KZ86
uniprot id: A0A7E6D4C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

89673:DNHD1
gene id: 89673:DNHD1
uniprot id: A0A7E6E4C1
names: Similarity
messages: Belongs to the dynein heavy chain family.

89673:YTHDC1
gene id: 89673:YTHDC1
uniprot id: A0A6J2L6Q0
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

89673:YPEL5
gene id: 89673:YPEL5
uniprot id: A0A6J2LZJ4
names: Similarity
messages: Belongs to the yippee family.

89673:CRIPT
gene id: 89673:CRIPT
uniprot id: A0A6J2LXU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRIPT family.
messages: Cytoplasm

89673:TMEM167A
gene id: 89673:TMEM167A
uniprot id: A0A7E6DB07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KISH family.
messages: Golgi apparatus membrane
messages: Involved in the early part of the secretory pathway.
messages: Membrane

89673:LOC114498460
gene id: 89673:LOC114498460
uniprot id: A0A7E6DB41
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

89673:CENPV
gene id: 89673:CENPV
uniprot id: A0A6J2NEG3
uniprot id: A0A7E6EBV8
names: Similarity
messages: Belongs to the Gfa family.

89673:LOC114490290
gene id: 89673:LOC114490290
uniprot id: A0A7E6E7K0
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

89673:GALNT10
gene id: 89673:GALNT10
uniprot id: A0A6J2N2U5
uniprot id: A0A7E6CT01
uniprot id: A0A7E6CT89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

89673:LOC118496835
gene id: 89673:LOC118496835
uniprot id: A0A7E6CG16
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

89673:BEST1
gene id: 89673:BEST1
uniprot id: A0A6J2LYI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.
messages: Cell membrane
messages: Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
messages: Membrane

89673:MBOAT1
gene id: 89673:MBOAT1
uniprot id: A0A6J2LUU6
names: Subcellular Location Annotation
messages: Membrane

89673:PRLR
gene id: 89673:PRLR
uniprot id: A0A6J2MYU4
uniprot id: A0A7E6DCV4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Interacts with SMARCA1. Interacts with NEK3 and VAV2 and this interaction is prolactin-dependent.
messages: Membrane
messages: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
messages: The box 1 motif is required for JAK interaction and/or activation.
messages: This is a receptor for the anterior pituitary hormone prolactin.

89673:SLC25A15
gene id: 89673:SLC25A15
uniprot id: A0A6J2MQJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

89673:CDC123
gene id: 89673:CDC123
uniprot id: A0A6J2LC63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC123 family.
messages: Cytoplasm
messages: Required for S phase entry of the cell cycle.

89673:RSRP1
gene id: 89673:RSRP1
uniprot id: A0A6J2LT24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RSRP family.
messages: Nucleus
messages: Probably acts as a spliceosomal factor that contributes to spliceosome assembly and regulates the isoform switching of proteins such as PARP6.

89673:FMC1
gene id: 89673:FMC1
uniprot id: A0A6J2MQT9
names: Similarity
messages: Belongs to the FMC1 family.

89673:ZEB2
gene id: 89673:ZEB2
uniprot id: A0A6J2L9G2
uniprot id: A0A7E6DK08
names: Similarity
messages: Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.

89673:TMEM177
gene id: 89673:TMEM177
uniprot id: A0A7E6DK92
names: Function
names: Similarity
messages: Belongs to the TMEM177 family.
messages: Plays a role in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation and is required for the stabilization of COX20 and the newly synthesized MT-CO2/COX2 protein.

89673:LOC114500117
gene id: 89673:LOC114500117
uniprot id: A0A6J2M378
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

89673:RXFP2
gene id: 89673:RXFP2
uniprot id: A0A6J2NGX4
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:JAG1
gene id: 89673:JAG1
uniprot id: A0A6J2MJ46
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

89673:VARS1
gene id: 89673:VARS1
uniprot id: A0A6J2LAB1
uniprot id: A0A7E6DL61
uniprot id: A0A7E6DLI9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

89673:AP3B1
gene id: 89673:AP3B1
uniprot id: A0A6J2N5M4
uniprot id: A0A7E6DAV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes large subunit family.
messages: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
messages: clathrin-coated vesicle membrane

89673:PRLHR
gene id: 89673:PRLHR
uniprot id: A0A7E6DVK6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:ATP2B3
gene id: 89673:ATP2B3
uniprot id: A0A6J2MIE5
uniprot id: A0A6J2MMG5
uniprot id: A0A7E6CYY4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

89673:NCSTN
gene id: 89673:NCSTN
uniprot id: A0A6J2N8V9
uniprot id: A0A7E6CVW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicastrin family.
messages: Membrane

89673:TENT5B
gene id: 89673:TENT5B
uniprot id: A0A6J2LPC2
names: Similarity
messages: Belongs to the TENT family.

89673:VAX1
gene id: 89673:VAX1
uniprot id: A0A6J2LLM6
names: Subcellular Location Annotation
messages: Nucleus

89673:PPARD
gene id: 89673:PPARD
uniprot id: A0A6J2LDA6
uniprot id: A0A6J2LI08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

89673:CMTM7
gene id: 89673:CMTM7
uniprot id: A0A6J2M4P4
names: Subcellular Location Annotation
messages: Membrane

89673:LOC114504678
gene id: 89673:LOC114504678
uniprot id: A0A7E6D0Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. As part of the U7 snRNP it is involved in histone 3'-end processing.
messages: cytosol

89673:LOC114510761
gene id: 89673:LOC114510761
uniprot id: A0A7E6CQK2
names: Similarity
messages: Belongs to the MHC class I family.

89673:SLC34A3
gene id: 89673:SLC34A3
uniprot id: A0A7E6DH41
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Membrane

89673:FBXO45
gene id: 89673:FBXO45
uniprot id: A0A6J2KY93
names: Similarity
messages: Belongs to the FBXO45/Fsn family.

89673:PSMD9
gene id: 89673:PSMD9
uniprot id: A0A6J2N219
names: Similarity
messages: Belongs to the proteasome subunit p27 family.

89673:LDAH
gene id: 89673:LDAH
uniprot id: A0A6J2LXN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. LDAH family.
messages: Lipid droplet

89673:MTIF3
gene id: 89673:MTIF3
uniprot id: A0A6J2L059
names: Similarity
messages: Belongs to the IF-3 family.

89673:LOC118498207
gene id: 89673:LOC118498207
uniprot id: A0A7E6CXG3
names: Similarity
messages: Belongs to the histone H3 family.

89673:LOC114511375
gene id: 89673:LOC114511375
uniprot id: A0A7E6CRB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

89673:LOC114491804
gene id: 89673:LOC114491804
uniprot id: A0A7E6DAD8
uniprot id: A0A7E6DAR2
uniprot id: A0A7E6DD56
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

89673:LACTB2
gene id: 89673:LACTB2
uniprot id: A0A6J2NAZ7
names: Function
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.

89673:ONECUT1
gene id: 89673:ONECUT1
uniprot id: A0A6J2LBJ3
uniprot id: A0A7E6EE79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

89673:LOC114496008
gene id: 89673:LOC114496008
uniprot id: A0A6J2LI26
names: Subcellular Location Annotation
messages: Nucleus

89673:GPR18
gene id: 89673:GPR18
uniprot id: A0A6J2MWI2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

89673:LOC114493964
gene id: 89673:LOC114493964
uniprot id: A0A7E6DIW0
names: Similarity
messages: Belongs to the NAC-beta family.

89673:RNH1
gene id: 89673:RNH1
uniprot id: A0A6J2LWL9
uniprot id: A0A6J2M0I3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Forms high-affinity heterodimers with RNASE1, ANG and RNASE2.
messages: Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play a role in redox homeostasis.

89673:LOC114493171
gene id: 89673:LOC114493171
uniprot id: A0A6J2LDJ3
names: Similarity
messages: Belongs to the FXYD family.

89673:LOC114497544
gene id: 89673:LOC114497544
uniprot id: A0A6J2LPA2
names: Similarity
names: Subunit
messages: Belongs to the SFTPD family.
messages: Oligomeric complex of 4 set of homotrimers.