889378:SPIAF RS02790
gene id: 889378:SPIAF_RS02790
uniprot id: H9UGL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

889378:SPIAF RS09900
gene id: 889378:SPIAF_RS09900
uniprot id: H9UKK6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

889378:SPIAF RS08050
gene id: 889378:SPIAF_RS08050
uniprot id: H9UJJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

889378:SPIAF RS08825
gene id: 889378:SPIAF_RS08825
uniprot id: H9UJZ8
names: Similarity
messages: Belongs to the peptidase C56 family.

889378:SPIAF RS12030
gene id: 889378:SPIAF_RS12030
uniprot id: H9ULR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

889378:SPIAF RS03515
gene id: 889378:SPIAF_RS03515
uniprot id: H9UH06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

889378:SPIAF RS10460
gene id: 889378:SPIAF_RS10460
uniprot id: H9UKW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

889378:SPIAF RS12725
gene id: 889378:SPIAF_RS12725
uniprot id: H9UM54
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS08945
gene id: 889378:SPIAF_RS08945
uniprot id: H9UK22
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS13395
gene id: 889378:SPIAF_RS13395
uniprot id: H9UMI2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS11660
gene id: 889378:SPIAF_RS11660
uniprot id: H9ULJ3
names: Similarity
messages: Belongs to the NodU/CmcH family.

889378:SPIAF RS07605
gene id: 889378:SPIAF_RS07605
uniprot id: H9UJA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

889378:SPIAF RS10465
gene id: 889378:SPIAF_RS10465
uniprot id: H9UKW7
names: Similarity
messages: Belongs to the DprA/Smf family.

889378:SPIAF RS07475
gene id: 889378:SPIAF_RS07475
uniprot id: H9UJ81
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

889378:SPIAF RS02925
gene id: 889378:SPIAF_RS02925
uniprot id: H9UGN9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

889378:SPIAF RS09785
gene id: 889378:SPIAF_RS09785
uniprot id: H9UKI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

889378:SPIAF RS14140
gene id: 889378:SPIAF_RS14140
uniprot id: H9UMY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homodimer.

889378:SPIAF RS13475
gene id: 889378:SPIAF_RS13475
uniprot id: H9UMJ8
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

889378:SPIAF RS08300
gene id: 889378:SPIAF_RS08300
uniprot id: H9UJP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

889378:SPIAF RS04920
gene id: 889378:SPIAF_RS04920
uniprot id: H9UHT4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

889378:SPIAF RS01845
gene id: 889378:SPIAF_RS01845
uniprot id: H9UG28
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

889378:SPIAF RS09835
gene id: 889378:SPIAF_RS09835
uniprot id: H9UKJ3
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

889378:SPIAF RS03520
gene id: 889378:SPIAF_RS03520
uniprot id: H9UH07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

889378:SPIAF RS05005
gene id: 889378:SPIAF_RS05005
uniprot id: H9UHV1
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

889378:SPIAF RS09285
gene id: 889378:SPIAF_RS09285
uniprot id: H9UK88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

889378:SPIAF RS05275
gene id: 889378:SPIAF_RS05275
uniprot id: H9UI06
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS12340
gene id: 889378:SPIAF_RS12340
uniprot id: H9ULX8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS00890
gene id: 889378:SPIAF_RS00890
uniprot id: H9UFJ3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

889378:SPIAF RS13905
gene id: 889378:SPIAF_RS13905
uniprot id: H9UMT4
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS10130
gene id: 889378:SPIAF_RS10130
uniprot id: H9UKQ0
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

889378:SPIAF RS10515
gene id: 889378:SPIAF_RS10515
uniprot id: H9UKX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

889378:SPIAF RS10455
gene id: 889378:SPIAF_RS10455
uniprot id: H9UKW5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

889378:SPIAF RS12070
gene id: 889378:SPIAF_RS12070
uniprot id: H9ULS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer.

889378:SPIAF RS06565
gene id: 889378:SPIAF_RS06565
uniprot id: H9UIQ6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

889378:SPIAF RS03490
gene id: 889378:SPIAF_RS03490
uniprot id: H9UH01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

889378:SPIAF RS14935
gene id: 889378:SPIAF_RS14935
uniprot id: H9UK55
names: Similarity
messages: Belongs to the peptidase A24 family.

889378:SPIAF RS06005
gene id: 889378:SPIAF_RS06005
uniprot id: H9UIE7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

889378:SPIAF RS02045
gene id: 889378:SPIAF_RS02045
uniprot id: H9UG66
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

889378:SPIAF RS10410
gene id: 889378:SPIAF_RS10410
uniprot id: H9UKV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

889378:SPIAF RS06555
gene id: 889378:SPIAF_RS06555
uniprot id: H9UIQ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

889378:SPIAF RS00780
gene id: 889378:SPIAF_RS00780
uniprot id: H9UFH1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

889378:SPIAF RS04125
gene id: 889378:SPIAF_RS04125
uniprot id: H9UHC5
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

889378:SPIAF RS08940
gene id: 889378:SPIAF_RS08940
uniprot id: H9UK21
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS00325
gene id: 889378:SPIAF_RS00325
uniprot id: H9UF80
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

889378:SPIAF RS07915
gene id: 889378:SPIAF_RS07915
uniprot id: H9UJG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

889378:SPIAF RS02215
gene id: 889378:SPIAF_RS02215
uniprot id: H9UG99
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

889378:SPIAF RS02200
gene id: 889378:SPIAF_RS02200
uniprot id: H9UG96
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

889378:SPIAF RS00030
gene id: 889378:SPIAF_RS00030
uniprot id: H9UF22
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

889378:SPIAF RS13090
gene id: 889378:SPIAF_RS13090
uniprot id: H9UMC2
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS04605
gene id: 889378:SPIAF_RS04605
uniprot id: H9UHM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

889378:SPIAF RS06045
gene id: 889378:SPIAF_RS06045
uniprot id: H9UIF5
names: Similarity
messages: Belongs to the UPF0102 family.

889378:SPIAF RS09920
gene id: 889378:SPIAF_RS09920
uniprot id: H9UKL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

889378:SPIAF RS14255
gene id: 889378:SPIAF_RS14255
uniprot id: H9UMZ9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

889378:SPIAF RS13550
gene id: 889378:SPIAF_RS13550
uniprot id: H9UML2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

889378:SPIAF RS00795
gene id: 889378:SPIAF_RS00795
uniprot id: H9UFH4
names: Function
names: Similarity
messages: Belongs to the bacterial histone-like protein family.
messages: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.

889378:SPIAF RS07310
gene id: 889378:SPIAF_RS07310
uniprot id: H9UJ50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

889378:SPIAF RS07095
gene id: 889378:SPIAF_RS07095
uniprot id: H9UJ09
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

889378:SPIAF RS04865
gene id: 889378:SPIAF_RS04865
uniprot id: H9UHS3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

889378:SPIAF RS03570
gene id: 889378:SPIAF_RS03570
uniprot id: H9UH16
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

889378:SPIAF RS10885
gene id: 889378:SPIAF_RS10885
uniprot id: H9UL41
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS11740
gene id: 889378:SPIAF_RS11740
uniprot id: H9ULK9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

889378:SPIAF RS07590
gene id: 889378:SPIAF_RS07590
uniprot id: H9UJA4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

889378:SPIAF RS02095
gene id: 889378:SPIAF_RS02095
uniprot id: H9UG75
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS04980
gene id: 889378:SPIAF_RS04980
uniprot id: H9UHU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

889378:SPIAF RS13815
gene id: 889378:SPIAF_RS13815
uniprot id: H9UMR5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

889378:SPIAF RS12620
gene id: 889378:SPIAF_RS12620
uniprot id: H9UM33
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

889378:SPIAF RS10220
gene id: 889378:SPIAF_RS10220
uniprot id: H9UKR7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

889378:SPIAF RS08845
gene id: 889378:SPIAF_RS08845
uniprot id: H9UK02
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

889378:SPIAF RS11430
gene id: 889378:SPIAF_RS11430
uniprot id: H9ULE7
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS14070
gene id: 889378:SPIAF_RS14070
uniprot id: H9UMW7
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

889378:SPIAF RS01615
gene id: 889378:SPIAF_RS01615
uniprot id: H9UFY4
names: Similarity
messages: Belongs to the MEMO1 family.

889378:SPIAF RS04120
gene id: 889378:SPIAF_RS04120
uniprot id: H9UHC4
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

889378:SPIAF RS03290
gene id: 889378:SPIAF_RS03290
uniprot id: H9UGW1
names: Similarity
messages: Belongs to the UMP kinase family.

889378:SPIAF RS11635
gene id: 889378:SPIAF_RS11635
uniprot id: H9ULI7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

889378:SPIAF RS14535
gene id: 889378:SPIAF_RS14535
uniprot id: H9UH29
names: Similarity
messages: Belongs to the peptidase C40 family.

889378:SPIAF RS02995
gene id: 889378:SPIAF_RS02995
uniprot id: H9UGQ2
names: Similarity
messages: Belongs to the aspartokinase family.

889378:SPIAF RS05575
gene id: 889378:SPIAF_RS05575
uniprot id: H1NDE6
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

889378:SPIAF RS10330
gene id: 889378:SPIAF_RS10330
uniprot id: H9UKU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

889378:SPIAF RS06600
gene id: 889378:SPIAF_RS06600
uniprot id: H9UIR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

889378:SPIAF RS03005
gene id: 889378:SPIAF_RS03005
uniprot id: H9UGQ4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

889378:SPIAF RS07260
gene id: 889378:SPIAF_RS07260
uniprot id: H9UJ41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

889378:SPIAF RS13890
gene id: 889378:SPIAF_RS13890
uniprot id: H9UMT1
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

889378:SPIAF RS01065
gene id: 889378:SPIAF_RS01065
uniprot id: H9UFM8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

889378:SPIAF RS03740
gene id: 889378:SPIAF_RS03740
uniprot id: H9UH49
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.

889378:SPIAF RS12770
gene id: 889378:SPIAF_RS12770
uniprot id: H9UM63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

889378:SPIAF RS09765
gene id: 889378:SPIAF_RS09765
uniprot id: H9UKI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

889378:SPIAF RS06925
gene id: 889378:SPIAF_RS06925
uniprot id: H1NDE6
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

889378:SPIAF RS08905
gene id: 889378:SPIAF_RS08905
uniprot id: H9UK14
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

889378:SPIAF RS13500
gene id: 889378:SPIAF_RS13500
uniprot id: H9UMK3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

889378:SPIAF RS02105
gene id: 889378:SPIAF_RS02105
uniprot id: H9UG77
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

889378:SPIAF RS04655
gene id: 889378:SPIAF_RS04655
uniprot id: H9UHN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

889378:SPIAF RS03160
gene id: 889378:SPIAF_RS03160
uniprot id: H9UGT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AlgF family.
messages: Periplasm

889378:SPIAF RS09670
gene id: 889378:SPIAF_RS09670
uniprot id: H9UKG1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

889378:SPIAF RS04785
gene id: 889378:SPIAF_RS04785
uniprot id: H9UHQ8
names: Similarity
messages: Belongs to the UPF0145 family.

889378:SPIAF RS08055
gene id: 889378:SPIAF_RS08055
uniprot id: H9UJJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

889378:SPIAF RS06820
gene id: 889378:SPIAF_RS06820
uniprot id: H9UIV3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

889378:SPIAF RS05060
gene id: 889378:SPIAF_RS05060
uniprot id: H1NDE6
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

889378:SPIAF RS10830
gene id: 889378:SPIAF_RS10830
uniprot id: H9UL29
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

889378:SPIAF RS02260
gene id: 889378:SPIAF_RS02260
uniprot id: H9UGA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

889378:SPIAF RS03400
gene id: 889378:SPIAF_RS03400
uniprot id: H9UGY3
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

889378:SPIAF RS00860
gene id: 889378:SPIAF_RS00860
uniprot id: H9UFI7
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS05900
gene id: 889378:SPIAF_RS05900
uniprot id: H9UIC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

889378:SPIAF RS05395
gene id: 889378:SPIAF_RS05395
uniprot id: H9UI31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

889378:SPIAF RS00675
gene id: 889378:SPIAF_RS00675
uniprot id: H9UFE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

889378:SPIAF RS07690
gene id: 889378:SPIAF_RS07690
uniprot id: H9UJC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

889378:SPIAF RS13695
gene id: 889378:SPIAF_RS13695
uniprot id: H9UMP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

889378:SPIAF RS02340
gene id: 889378:SPIAF_RS02340
uniprot id: H9UGC3
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

889378:SPIAF RS00995
gene id: 889378:SPIAF_RS00995
uniprot id: H9UFL4
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS03840
gene id: 889378:SPIAF_RS03840
uniprot id: H9UH69
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

889378:SPIAF RS10450
gene id: 889378:SPIAF_RS10450
uniprot id: H9UKW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

889378:SPIAF RS14075
gene id: 889378:SPIAF_RS14075
uniprot id: H9UMW8
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

889378:SPIAF RS08470
gene id: 889378:SPIAF_RS08470
uniprot id: H9UJS8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

889378:SPIAF RS12145
gene id: 889378:SPIAF_RS12145
uniprot id: H9ULT9
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

889378:SPIAF RS10155
gene id: 889378:SPIAF_RS10155
uniprot id: H9UKQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

889378:SPIAF RS00740
gene id: 889378:SPIAF_RS00740
uniprot id: H9UFG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

889378:SPIAF RS09945
gene id: 889378:SPIAF_RS09945
uniprot id: H9UKL5
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS09880
gene id: 889378:SPIAF_RS09880
uniprot id: H9UKK2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

889378:SPIAF RS14995
gene id: 889378:SPIAF_RS14995
uniprot id: H9UKW1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

889378:SPIAF RS14040
gene id: 889378:SPIAF_RS14040
uniprot id: H9UMW1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

889378:SPIAF RS13155
gene id: 889378:SPIAF_RS13155
uniprot id: H9UMD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

889378:SPIAF RS02710
gene id: 889378:SPIAF_RS02710
uniprot id: H9UGJ7
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

889378:SPIAF RS05810
gene id: 889378:SPIAF_RS05810
uniprot id: H9UIA9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

889378:SPIAF RS01545
gene id: 889378:SPIAF_RS01545
uniprot id: H9UFX2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

889378:SPIAF RS08645
gene id: 889378:SPIAF_RS08645
uniprot id: H9UJW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

889378:SPIAF RS05355
gene id: 889378:SPIAF_RS05355
uniprot id: H9UI23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

889378:SPIAF RS07115
gene id: 889378:SPIAF_RS07115
uniprot id: H9UJ13
names: Similarity
messages: Belongs to the RecJ family.

889378:SPIAF RS12215
gene id: 889378:SPIAF_RS12215
uniprot id: H9ULV3
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

889378:SPIAF RS04240
gene id: 889378:SPIAF_RS04240
uniprot id: H9UHE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

889378:SPIAF RS09280
gene id: 889378:SPIAF_RS09280
uniprot id: H9UK87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

889378:SPIAF RS01640
gene id: 889378:SPIAF_RS01640
uniprot id: H9UFY9
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

889378:SPIAF RS01320
gene id: 889378:SPIAF_RS01320
uniprot id: H9UFS8
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

889378:SPIAF RS00975
gene id: 889378:SPIAF_RS00975
uniprot id: H9UFL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

889378:SPIAF RS06410
gene id: 889378:SPIAF_RS06410
uniprot id: H9UIM6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

889378:SPIAF RS05315
gene id: 889378:SPIAF_RS05315
uniprot id: H9UI14
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

889378:SPIAF RS03245
gene id: 889378:SPIAF_RS03245
uniprot id: H9UGV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

889378:SPIAF RS08730
gene id: 889378:SPIAF_RS08730
uniprot id: H9UJX9
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

889378:SPIAF RS02440
gene id: 889378:SPIAF_RS02440
uniprot id: H9UGE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS08155
gene id: 889378:SPIAF_RS08155
uniprot id: H9UJL6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

889378:SPIAF RS01025
gene id: 889378:SPIAF_RS01025
uniprot id: H9UFM0
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS03135
gene id: 889378:SPIAF_RS03135
uniprot id: H9UGT0
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS02875
gene id: 889378:SPIAF_RS02875
uniprot id: H9UGM9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

889378:SPIAF RS03225
gene id: 889378:SPIAF_RS03225
uniprot id: H9UGU8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

889378:SPIAF RS03185
gene id: 889378:SPIAF_RS03185
uniprot id: H9UGU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

889378:SPIAF RS00875
gene id: 889378:SPIAF_RS00875
uniprot id: H9UFJ0
names: Similarity
messages: Belongs to the band 7/mec-2 family.

889378:SPIAF RS05325
gene id: 889378:SPIAF_RS05325
uniprot id: H9UI17
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

889378:SPIAF RS02895
gene id: 889378:SPIAF_RS02895
uniprot id: H9UGN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

889378:SPIAF RS03785
gene id: 889378:SPIAF_RS03785
uniprot id: H9UH58
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

889378:SPIAF RS10440
gene id: 889378:SPIAF_RS10440
uniprot id: H9UKW2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

889378:SPIAF RS13215
gene id: 889378:SPIAF_RS13215
uniprot id: H9UME7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

889378:SPIAF RS04710
gene id: 889378:SPIAF_RS04710
uniprot id: H9UHP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

889378:SPIAF RS12655
gene id: 889378:SPIAF_RS12655
uniprot id: H9UM40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

889378:SPIAF RS01305
gene id: 889378:SPIAF_RS01305
uniprot id: H9UFS5
names: Similarity
messages: Belongs to the UDPGP type 2 family.

889378:SPIAF RS12005
gene id: 889378:SPIAF_RS12005
uniprot id: H9ULR1
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

889378:SPIAF RS13800
gene id: 889378:SPIAF_RS13800
uniprot id: H9UMR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

889378:SPIAF RS02760
gene id: 889378:SPIAF_RS02760
uniprot id: H9UGK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

889378:SPIAF RS01800
gene id: 889378:SPIAF_RS01800
uniprot id: H9UG18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

889378:SPIAF RS02640
gene id: 889378:SPIAF_RS02640
uniprot id: H9UGI3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

889378:SPIAF RS07430
gene id: 889378:SPIAF_RS07430
uniprot id: H9UJ72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

889378:SPIAF RS08080
gene id: 889378:SPIAF_RS08080
uniprot id: H9UJK1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

889378:SPIAF RS12720
gene id: 889378:SPIAF_RS12720
uniprot id: H9UM53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

889378:SPIAF RS02860
gene id: 889378:SPIAF_RS02860
uniprot id: H9UGM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

889378:SPIAF RS05715
gene id: 889378:SPIAF_RS05715
uniprot id: H9UI89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

889378:SPIAF RS11530
gene id: 889378:SPIAF_RS11530
uniprot id: H9ULG6
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS02645
gene id: 889378:SPIAF_RS02645
uniprot id: H9UGI4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS13365
gene id: 889378:SPIAF_RS13365
uniprot id: H9UMH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

889378:SPIAF RS06315
gene id: 889378:SPIAF_RS06315
uniprot id: H9UIK7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS06670
gene id: 889378:SPIAF_RS06670
uniprot id: H9UIS1
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS06020
gene id: 889378:SPIAF_RS06020
uniprot id: H9UIF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

889378:SPIAF RS11465
gene id: 889378:SPIAF_RS11465
uniprot id: H9ULF3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

889378:SPIAF RS00685
gene id: 889378:SPIAF_RS00685
uniprot id: H9UFF1
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

889378:SPIAF RS11200
gene id: 889378:SPIAF_RS11200
uniprot id: H9ULA4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

889378:SPIAF RS07445
gene id: 889378:SPIAF_RS07445
uniprot id: H1NDE6
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

889378:SPIAF RS13860
gene id: 889378:SPIAF_RS13860
uniprot id: H9UMS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

889378:SPIAF RS13095
gene id: 889378:SPIAF_RS13095
uniprot id: H9UMC3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS05905
gene id: 889378:SPIAF_RS05905
uniprot id: H9UIC8
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

889378:SPIAF RS03935
gene id: 889378:SPIAF_RS03935
uniprot id: H9UH88
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

889378:SPIAF RS09320
gene id: 889378:SPIAF_RS09320
uniprot id: H9UK94
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

889378:SPIAF RS12635
gene id: 889378:SPIAF_RS12635
uniprot id: H9UM36
names: Function
names: Similarity
messages: Belongs to the TrpF family.
messages: Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.
messages: In the C-terminal section; belongs to the TrpF family.
messages: In the N-terminal section; belongs to the TrpC family.

889378:SPIAF RS09555
gene id: 889378:SPIAF_RS09555
uniprot id: H9UKD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

889378:SPIAF RS08475
gene id: 889378:SPIAF_RS08475
uniprot id: H9UJS9
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS07660
gene id: 889378:SPIAF_RS07660
uniprot id: H9UJB8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

889378:SPIAF RS06875
gene id: 889378:SPIAF_RS06875
uniprot id: H9UIW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

889378:SPIAF RS10965
gene id: 889378:SPIAF_RS10965
uniprot id: H9UL57
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

889378:SPIAF RS05640
gene id: 889378:SPIAF_RS05640
uniprot id: H9UI79
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

889378:SPIAF RS05850
gene id: 889378:SPIAF_RS05850
uniprot id: H9UIB7
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

889378:SPIAF RS09700
gene id: 889378:SPIAF_RS09700
uniprot id: H9UKG7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

889378:SPIAF RS02605
gene id: 889378:SPIAF_RS02605
uniprot id: H9UGH6
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS10740
gene id: 889378:SPIAF_RS10740
uniprot id: H9UL12
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

889378:SPIAF RS00665
gene id: 889378:SPIAF_RS00665
uniprot id: H9UFE7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

889378:SPIAF RS09405
gene id: 889378:SPIAF_RS09405
uniprot id: H9UKB0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

889378:SPIAF RS09955
gene id: 889378:SPIAF_RS09955
uniprot id: H9UKL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

889378:SPIAF RS14080
gene id: 889378:SPIAF_RS14080
uniprot id: H9UMW9
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

889378:SPIAF RS11810
gene id: 889378:SPIAF_RS11810
uniprot id: H9ULM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

889378:SPIAF RS02805
gene id: 889378:SPIAF_RS02805
uniprot id: H9UGL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

889378:SPIAF RS05920
gene id: 889378:SPIAF_RS05920
uniprot id: H9UID1
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

889378:SPIAF RS03165
gene id: 889378:SPIAF_RS03165
uniprot id: H9UGT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

889378:SPIAF RS11590
gene id: 889378:SPIAF_RS11590
uniprot id: H9ULH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

889378:SPIAF RS00490
gene id: 889378:SPIAF_RS00490
uniprot id: H9UFB2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

889378:SPIAF RS12830
gene id: 889378:SPIAF_RS12830
uniprot id: H9UM75
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

889378:SPIAF RS03020
gene id: 889378:SPIAF_RS03020
uniprot id: H9UGQ7
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

889378:SPIAF RS03335
gene id: 889378:SPIAF_RS03335
uniprot id: H9UGX0
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

889378:SPIAF RS06675
gene id: 889378:SPIAF_RS06675
uniprot id: H9UIS2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

889378:SPIAF RS08555
gene id: 889378:SPIAF_RS08555
uniprot id: H9UJU5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

889378:SPIAF RS01530
gene id: 889378:SPIAF_RS01530
uniprot id: H9UFW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

889378:SPIAF RS02780
gene id: 889378:SPIAF_RS02780
uniprot id: H9UGK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

889378:SPIAF RS02800
gene id: 889378:SPIAF_RS02800
uniprot id: H9UGL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

889378:SPIAF RS01280
gene id: 889378:SPIAF_RS01280
uniprot id: H9UFS0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

889378:SPIAF RS12605
gene id: 889378:SPIAF_RS12605
uniprot id: H9UM30
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

889378:SPIAF RS05875
gene id: 889378:SPIAF_RS05875
uniprot id: H9UIC2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

889378:SPIAF RS11050
gene id: 889378:SPIAF_RS11050
uniprot id: H9UL74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

889378:SPIAF RS09225
gene id: 889378:SPIAF_RS09225
uniprot id: H9UK76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

889378:SPIAF RS14335
gene id: 889378:SPIAF_RS14335
uniprot id: H9UFF6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

889378:SPIAF RS11095
gene id: 889378:SPIAF_RS11095
uniprot id: H9UL83
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS01110
gene id: 889378:SPIAF_RS01110
uniprot id: H9UFN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

889378:SPIAF RS07580
gene id: 889378:SPIAF_RS07580
uniprot id: H9UJA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

889378:SPIAF RS08260
gene id: 889378:SPIAF_RS08260
uniprot id: H9UJN6
names: Subcellular Location Annotation
messages: Periplasmic flagellum

889378:SPIAF RS12670
gene id: 889378:SPIAF_RS12670
uniprot id: H9UM43
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

889378:SPIAF RS11535
gene id: 889378:SPIAF_RS11535
uniprot id: H9ULG7
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS00415
gene id: 889378:SPIAF_RS00415
uniprot id: H9UF98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

889378:SPIAF RS02320
gene id: 889378:SPIAF_RS02320
uniprot id: H9UGB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

889378:SPIAF RS13785
gene id: 889378:SPIAF_RS13785
uniprot id: H9UMQ9
names: Similarity
messages: Belongs to the peptidase S41A family.

889378:SPIAF RS10375
gene id: 889378:SPIAF_RS10375
uniprot id: H9UKU9
names: Similarity
messages: Belongs to the MotB family.

889378:SPIAF RS08430
gene id: 889378:SPIAF_RS08430
uniprot id: H9UJS0
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS11470
gene id: 889378:SPIAF_RS11470
uniprot id: H9ULF4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

889378:SPIAF RS10910
gene id: 889378:SPIAF_RS10910
uniprot id: H9UL46
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

889378:SPIAF RS12105
gene id: 889378:SPIAF_RS12105
uniprot id: H9ULT1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

889378:SPIAF RS05685
gene id: 889378:SPIAF_RS05685
uniprot id: H9UI83
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

889378:SPIAF RS09680
gene id: 889378:SPIAF_RS09680
uniprot id: H9UKG3
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

889378:SPIAF RS02695
gene id: 889378:SPIAF_RS02695
uniprot id: H9UGJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

889378:SPIAF RS10430
gene id: 889378:SPIAF_RS10430
uniprot id: H9UKW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

889378:SPIAF RS12350
gene id: 889378:SPIAF_RS12350
uniprot id: H9ULY0
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

889378:SPIAF RS09685
gene id: 889378:SPIAF_RS09685
uniprot id: H9UKG4
names: Similarity
messages: Belongs to the GARS family.

889378:SPIAF RS05500
gene id: 889378:SPIAF_RS05500
uniprot id: H9UI52
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

889378:SPIAF RS13710
gene id: 889378:SPIAF_RS13710
uniprot id: H9UMP4
names: Similarity
messages: Belongs to the threonine synthase family.

889378:SPIAF RS02245
gene id: 889378:SPIAF_RS02245
uniprot id: H9UGA4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

889378:SPIAF RS02365
gene id: 889378:SPIAF_RS02365
uniprot id: H9UGC8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

889378:SPIAF RS08160
gene id: 889378:SPIAF_RS08160
uniprot id: H9UJL7
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

889378:SPIAF RS10400
gene id: 889378:SPIAF_RS10400
uniprot id: H9UKV4
names: Function
names: Similarity
messages: Belongs to the FliK family.
messages: Controls the length of the flagellar hook.

889378:SPIAF RS09145
gene id: 889378:SPIAF_RS09145
uniprot id: H9UK62
names: Similarity
messages: Belongs to the CarB family.

889378:SPIAF RS14190
gene id: 889378:SPIAF_RS14190
uniprot id: H9UMZ1
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

889378:SPIAF RS08910
gene id: 889378:SPIAF_RS08910
uniprot id: H9UK15
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

889378:SPIAF RS01450
gene id: 889378:SPIAF_RS01450
uniprot id: H9UFV3
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

889378:SPIAF RS13360
gene id: 889378:SPIAF_RS13360
uniprot id: H9UMH5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

889378:SPIAF RS06015
gene id: 889378:SPIAF_RS06015
uniprot id: H9UIE9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

889378:SPIAF RS11175
gene id: 889378:SPIAF_RS11175
uniprot id: H9UL99
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS00505
gene id: 889378:SPIAF_RS00505
uniprot id: H9UFB5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

889378:SPIAF RS12275
gene id: 889378:SPIAF_RS12275
uniprot id: H9ULW5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

889378:SPIAF RS09030
gene id: 889378:SPIAF_RS09030
uniprot id: H9UK39
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

889378:SPIAF RS03035
gene id: 889378:SPIAF_RS03035
uniprot id: H9UGQ9
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS14095
gene id: 889378:SPIAF_RS14095
uniprot id: H9UMX2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

889378:SPIAF RS10995
gene id: 889378:SPIAF_RS10995
uniprot id: H9UL63
names: Similarity
messages: Belongs to the polysaccharide synthase family.

889378:SPIAF RS12100
gene id: 889378:SPIAF_RS12100
uniprot id: H9ULT0
names: Function
names: Subunit
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

889378:SPIAF RS15185
gene id: 889378:SPIAF_RS15185
uniprot id: H9UML1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

889378:SPIAF RS03970
gene id: 889378:SPIAF_RS03970
uniprot id: H9UH95
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

889378:SPIAF RS00980
gene id: 889378:SPIAF_RS00980
uniprot id: H9UFL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

889378:SPIAF RS09895
gene id: 889378:SPIAF_RS09895
uniprot id: H9UKK5
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS11075
gene id: 889378:SPIAF_RS11075
uniprot id: H9UL79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

889378:SPIAF RS02890
gene id: 889378:SPIAF_RS02890
uniprot id: H9UGN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

889378:SPIAF RS02795
gene id: 889378:SPIAF_RS02795
uniprot id: H9UGL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

889378:SPIAF RS09345
gene id: 889378:SPIAF_RS09345
uniprot id: H9UK99
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

889378:SPIAF RS07655
gene id: 889378:SPIAF_RS07655
uniprot id: H9UJB7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

889378:SPIAF RS10035
gene id: 889378:SPIAF_RS10035
uniprot id: H9UKN2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

889378:SPIAF RS02835
gene id: 889378:SPIAF_RS02835
uniprot id: H9UGM0
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

889378:SPIAF RS11000
gene id: 889378:SPIAF_RS11000
uniprot id: H9UL64
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

889378:SPIAF RS08225
gene id: 889378:SPIAF_RS08225
uniprot id: H9UJN0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS02830
gene id: 889378:SPIAF_RS02830
uniprot id: H9UGL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

889378:SPIAF RS06235
gene id: 889378:SPIAF_RS06235
uniprot id: H9UIJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

889378:SPIAF RS12020
gene id: 889378:SPIAF_RS12020
uniprot id: H9ULR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

889378:SPIAF RS00035
gene id: 889378:SPIAF_RS00035
uniprot id: H9UF24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

889378:SPIAF RS08980
gene id: 889378:SPIAF_RS08980
uniprot id: H9UK29
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

889378:SPIAF RS02700
gene id: 889378:SPIAF_RS02700
uniprot id: H9UGJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

889378:SPIAF RS01890
gene id: 889378:SPIAF_RS01890
uniprot id: H9UG37
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

889378:SPIAF RS04665
gene id: 889378:SPIAF_RS04665
uniprot id: H9UHN4
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS02520
gene id: 889378:SPIAF_RS02520
uniprot id: H9UGF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

889378:SPIAF RS07540
gene id: 889378:SPIAF_RS07540
uniprot id: H9UJ94
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

889378:SPIAF RS11990
gene id: 889378:SPIAF_RS11990
uniprot id: H9ULQ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

889378:SPIAF RS12535
gene id: 889378:SPIAF_RS12535
uniprot id: H9UM16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

889378:SPIAF RS11995
gene id: 889378:SPIAF_RS11995
uniprot id: H9ULQ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

889378:SPIAF RS02785
gene id: 889378:SPIAF_RS02785
uniprot id: H9UGL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

889378:SPIAF RS14440
gene id: 889378:SPIAF_RS14440
uniprot id: H9UG46
names: Similarity
messages: Belongs to the peptidase S33 family.

889378:SPIAF RS12260
gene id: 889378:SPIAF_RS12260
uniprot id: H9ULW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

889378:SPIAF RS01405
gene id: 889378:SPIAF_RS01405
uniprot id: H9UFU4
names: Similarity
messages: Belongs to the glycosyl hydrolase.

889378:SPIAF RS09620
gene id: 889378:SPIAF_RS09620
uniprot id: H9UKF1
names: Function
names: Similarity
messages: Belongs to the bacterial histone-like protein family.
messages: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.

889378:SPIAF RS13240
gene id: 889378:SPIAF_RS13240
uniprot id: H9UMF2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

889378:SPIAF RS15195
gene id: 889378:SPIAF_RS15195
uniprot id: H9UML8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

889378:SPIAF RS15980
gene id: 889378:SPIAF_RS15980
uniprot id: H9UML4
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

889378:SPIAF RS01695
gene id: 889378:SPIAF_RS01695
uniprot id: H9UFZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

889378:SPIAF RS07515
gene id: 889378:SPIAF_RS07515
uniprot id: H9UJ89
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

889378:SPIAF RS03915
gene id: 889378:SPIAF_RS03915
uniprot id: H9UH84
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

889378:SPIAF RS10020
gene id: 889378:SPIAF_RS10020
uniprot id: H9UKM9
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

889378:SPIAF RS00165
gene id: 889378:SPIAF_RS00165
uniprot id: H9UF48
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

889378:SPIAF RS13385
gene id: 889378:SPIAF_RS13385
uniprot id: H9UMI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

889378:SPIAF RS13310
gene id: 889378:SPIAF_RS13310
uniprot id: H9UMG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

889378:SPIAF RS11240
gene id: 889378:SPIAF_RS11240
uniprot id: H9ULB2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

889378:SPIAF RS13205
gene id: 889378:SPIAF_RS13205
uniprot id: H9UME5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

889378:SPIAF RS08220
gene id: 889378:SPIAF_RS08220
uniprot id: H9UJM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

889378:SPIAF RS06970
gene id: 889378:SPIAF_RS06970
uniprot id: H9UIY4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

889378:SPIAF RS00945
gene id: 889378:SPIAF_RS00945
uniprot id: H9UFK4
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS14230
gene id: 889378:SPIAF_RS14230
uniprot id: H9UMZ4
names: Similarity
messages: Belongs to the ParB family.

889378:SPIAF RS05450
gene id: 889378:SPIAF_RS05450
uniprot id: H9UI42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

889378:SPIAF RS02420
gene id: 889378:SPIAF_RS02420
uniprot id: H9UGD8
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

889378:SPIAF RS12385
gene id: 889378:SPIAF_RS12385
uniprot id: H9ULY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

889378:SPIAF RS11650
gene id: 889378:SPIAF_RS11650
uniprot id: H9ULJ0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

889378:SPIAF RS00445
gene id: 889378:SPIAF_RS00445
uniprot id: H9UFA4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

889378:SPIAF RS10500
gene id: 889378:SPIAF_RS10500
uniprot id: H9UKX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

889378:SPIAF RS10125
gene id: 889378:SPIAF_RS10125
uniprot id: H9UKP9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

889378:SPIAF RS00015
gene id: 889378:SPIAF_RS00015
uniprot id: H9UF19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

889378:SPIAF RS00625
gene id: 889378:SPIAF_RS00625
uniprot id: H9UFD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

889378:SPIAF RS01090
gene id: 889378:SPIAF_RS01090
uniprot id: H9UFN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

889378:SPIAF RS03445
gene id: 889378:SPIAF_RS03445
uniprot id: H9UGZ2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

889378:SPIAF RS11030
gene id: 889378:SPIAF_RS11030
uniprot id: H9UL70
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

889378:SPIAF RS03620
gene id: 889378:SPIAF_RS03620
uniprot id: H9UH26
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

889378:SPIAF RS11915
gene id: 889378:SPIAF_RS11915
uniprot id: H9ULP3
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

889378:SPIAF RS03070
gene id: 889378:SPIAF_RS03070
uniprot id: H9UGR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

889378:SPIAF RS07485
gene id: 889378:SPIAF_RS07485
uniprot id: H9UJ83
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

889378:SPIAF RS15085
gene id: 889378:SPIAF_RS15085
uniprot id: H9ULG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

889378:SPIAF RS04060
gene id: 889378:SPIAF_RS04060
uniprot id: H9UHB3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

889378:SPIAF RS10880
gene id: 889378:SPIAF_RS10880
uniprot id: H9UL40
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS06340
gene id: 889378:SPIAF_RS06340
uniprot id: H9UIL2
names: Similarity
messages: Belongs to the SufE family.

889378:SPIAF RS14525
gene id: 889378:SPIAF_RS14525
uniprot id: H9UGY8
names: Similarity
messages: Belongs to the peptidase S8 family.

889378:SPIAF RS05230
gene id: 889378:SPIAF_RS05230
uniprot id: H9UHZ7
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

889378:SPIAF RS10205
gene id: 889378:SPIAF_RS10205
uniprot id: H9UKR5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

889378:SPIAF RS06010
gene id: 889378:SPIAF_RS06010
uniprot id: H9UIE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

889378:SPIAF RS09890
gene id: 889378:SPIAF_RS09890
uniprot id: H9UKK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

889378:SPIAF RS09010
gene id: 889378:SPIAF_RS09010
uniprot id: H9UK35
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

889378:SPIAF RS03350
gene id: 889378:SPIAF_RS03350
uniprot id: H9UGX3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

889378:SPIAF RS11595
gene id: 889378:SPIAF_RS11595
uniprot id: H9ULH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

889378:SPIAF RS09545
gene id: 889378:SPIAF_RS09545
uniprot id: H9UKD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

889378:SPIAF RS09015
gene id: 889378:SPIAF_RS09015
uniprot id: H9UK36
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS06460
gene id: 889378:SPIAF_RS06460
uniprot id: H9UIN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

889378:SPIAF RS03585
gene id: 889378:SPIAF_RS03585
uniprot id: U3GKT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

889378:SPIAF RS11610
gene id: 889378:SPIAF_RS11610
uniprot id: H9ULI2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

889378:SPIAF RS11100
gene id: 889378:SPIAF_RS11100
uniprot id: H9UL84
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

889378:SPIAF RS06400
gene id: 889378:SPIAF_RS06400
uniprot id: H9UIM4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS12265
gene id: 889378:SPIAF_RS12265
uniprot id: H9ULW3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

889378:SPIAF RS01685
gene id: 889378:SPIAF_RS01685
uniprot id: H9UFZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

889378:SPIAF RS12630
gene id: 889378:SPIAF_RS12630
uniprot id: H9UM35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

889378:SPIAF RS15825
gene id: 889378:SPIAF_RS15825
uniprot id: H9UJ82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

889378:SPIAF RS10555
gene id: 889378:SPIAF_RS10555
uniprot id: H9UKY6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS03435
gene id: 889378:SPIAF_RS03435
uniprot id: H9UGZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

889378:SPIAF RS09330
gene id: 889378:SPIAF_RS09330
uniprot id: H9UK96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

889378:SPIAF RS05650
gene id: 889378:SPIAF_RS05650
uniprot id: H9UI81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

889378:SPIAF RS01245
gene id: 889378:SPIAF_RS01245
uniprot id: H9UFR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

889378:SPIAF RS04455
gene id: 889378:SPIAF_RS04455
uniprot id: H9UHJ4
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

889378:SPIAF RS02965
gene id: 889378:SPIAF_RS02965
uniprot id: H9UGP7
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS04460
gene id: 889378:SPIAF_RS04460
uniprot id: H9UHJ5
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS12685
gene id: 889378:SPIAF_RS12685
uniprot id: H9UM46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

889378:SPIAF RS08520
gene id: 889378:SPIAF_RS08520
uniprot id: H9UJT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.

889378:SPIAF RS08400
gene id: 889378:SPIAF_RS08400
uniprot id: H9UJR4
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

889378:SPIAF RS08380
gene id: 889378:SPIAF_RS08380
uniprot id: H9UJR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

889378:SPIAF RS07575
gene id: 889378:SPIAF_RS07575
uniprot id: H9UJA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

889378:SPIAF RS05635
gene id: 889378:SPIAF_RS05635
uniprot id: H9UI78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

889378:SPIAF RS12650
gene id: 889378:SPIAF_RS12650
uniprot id: H9UM39
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS10550
gene id: 889378:SPIAF_RS10550
uniprot id: H9UKY5
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

889378:SPIAF RS13270
gene id: 889378:SPIAF_RS13270
uniprot id: H9UMF8
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS02590
gene id: 889378:SPIAF_RS02590
uniprot id: H9UGH3
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS05910
gene id: 889378:SPIAF_RS05910
uniprot id: H9UIC9
names: Similarity
messages: Belongs to the arginine deiminase family.

889378:SPIAF RS13485
gene id: 889378:SPIAF_RS13485
uniprot id: U3GJI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

889378:SPIAF RS12110
gene id: 889378:SPIAF_RS12110
uniprot id: H9ULT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

889378:SPIAF RS12055
gene id: 889378:SPIAF_RS12055
uniprot id: H9ULS1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

889378:SPIAF RS13355
gene id: 889378:SPIAF_RS13355
uniprot id: H9UMH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

889378:SPIAF RS09875
gene id: 889378:SPIAF_RS09875
uniprot id: H9UKK1
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

889378:SPIAF RS00670
gene id: 889378:SPIAF_RS00670
uniprot id: H9UFE8
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS05145
gene id: 889378:SPIAF_RS05145
uniprot id: H9UHY0
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

889378:SPIAF RS14025
gene id: 889378:SPIAF_RS14025
uniprot id: H9UMV8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

889378:SPIAF RS06170
gene id: 889378:SPIAF_RS06170
uniprot id: H1NDE6
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

889378:SPIAF RS08095
gene id: 889378:SPIAF_RS08095
uniprot id: H9UJK4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

889378:SPIAF RS09065
gene id: 889378:SPIAF_RS09065
uniprot id: H9UK46
names: Similarity
messages: Belongs to the GSP E family.

889378:SPIAF RS08125
gene id: 889378:SPIAF_RS08125
uniprot id: H9UJL0
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

889378:SPIAF RS11505
gene id: 889378:SPIAF_RS11505
uniprot id: H9ULG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

889378:SPIAF RS02820
gene id: 889378:SPIAF_RS02820
uniprot id: H9UGL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

889378:SPIAF RS11385
gene id: 889378:SPIAF_RS11385
uniprot id: H9ULD8
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS00155
gene id: 889378:SPIAF_RS00155
uniprot id: H9UF46
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

889378:SPIAF RS10700
gene id: 889378:SPIAF_RS10700
uniprot id: H9UL05
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS00555
gene id: 889378:SPIAF_RS00555
uniprot id: H9UFC5
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

889378:SPIAF RS05895
gene id: 889378:SPIAF_RS05895
uniprot id: H9UIC6
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS06445
gene id: 889378:SPIAF_RS06445
uniprot id: H9UIN3
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

889378:SPIAF RS09710
gene id: 889378:SPIAF_RS09710
uniprot id: H9UKG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

889378:SPIAF RS10340
gene id: 889378:SPIAF_RS10340
uniprot id: U3GKU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

889378:SPIAF RS11130
gene id: 889378:SPIAF_RS11130
uniprot id: H9UL90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

889378:SPIAF RS06280
gene id: 889378:SPIAF_RS06280
uniprot id: H9UIK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

889378:SPIAF RS07835
gene id: 889378:SPIAF_RS07835
uniprot id: H9UJF3
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS09985
gene id: 889378:SPIAF_RS09985
uniprot id: H9UKM2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

889378:SPIAF RS02125
gene id: 889378:SPIAF_RS02125
uniprot id: H1NB75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

889378:SPIAF RS10875
gene id: 889378:SPIAF_RS10875
uniprot id: H9UL39
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

889378:SPIAF RS09550
gene id: 889378:SPIAF_RS09550
uniprot id: H9UKD7
names: Similarity
messages: Belongs to the ClpA/ClpB family.

889378:SPIAF RS13370
gene id: 889378:SPIAF_RS13370
uniprot id: H9UMH7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

889378:SPIAF RS10750
gene id: 889378:SPIAF_RS10750
uniprot id: H9UL14
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

889378:SPIAF RS03210
gene id: 889378:SPIAF_RS03210
uniprot id: H9UGU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

889378:SPIAF RS09165
gene id: 889378:SPIAF_RS09165
uniprot id: H9UK66
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

889378:SPIAF RS06980
gene id: 889378:SPIAF_RS06980
uniprot id: H9UIY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

889378:SPIAF RS01350
gene id: 889378:SPIAF_RS01350
uniprot id: H9UFT4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

889378:SPIAF RS10975
gene id: 889378:SPIAF_RS10975
uniprot id: H9UL59
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

889378:SPIAF RS04985
gene id: 889378:SPIAF_RS04985
uniprot id: H9UHU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

889378:SPIAF RS06000
gene id: 889378:SPIAF_RS06000
uniprot id: H9UIE6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

889378:SPIAF RS08500
gene id: 889378:SPIAF_RS08500
uniprot id: H9UJT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

889378:SPIAF RS06025
gene id: 889378:SPIAF_RS06025
uniprot id: H9UIF1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

889378:SPIAF RS00650
gene id: 889378:SPIAF_RS00650
uniprot id: H9UFE4
names: Similarity
messages: Belongs to the LacAB/RpiB family.

889378:SPIAF RS11525
gene id: 889378:SPIAF_RS11525
uniprot id: H9ULG5
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS14720
gene id: 889378:SPIAF_RS14720
uniprot id: H9UIA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

889378:SPIAF RS11615
gene id: 889378:SPIAF_RS11615
uniprot id: H9ULI3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

889378:SPIAF RS02130
gene id: 889378:SPIAF_RS02130
uniprot id: H9UG82
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS12740
gene id: 889378:SPIAF_RS12740
uniprot id: H9UM57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

889378:SPIAF RS04085
gene id: 889378:SPIAF_RS04085
uniprot id: H9UHB8
names: Subcellular Location Annotation
messages: Periplasmic flagellum

889378:SPIAF RS02690
gene id: 889378:SPIAF_RS02690
uniprot id: H9UGJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

889378:SPIAF RS01895
gene id: 889378:SPIAF_RS01895
uniprot id: H9UG38
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS02880
gene id: 889378:SPIAF_RS02880
uniprot id: H9UGN0
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

889378:SPIAF RS13340
gene id: 889378:SPIAF_RS13340
uniprot id: H9UMH1
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

889378:SPIAF RS10115
gene id: 889378:SPIAF_RS10115
uniprot id: H9UKP7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

889378:SPIAF RS02920
gene id: 889378:SPIAF_RS02920
uniprot id: H9UGN8
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

889378:SPIAF RS08365
gene id: 889378:SPIAF_RS08365
uniprot id: H9UJQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

889378:SPIAF RS04790
gene id: 889378:SPIAF_RS04790
uniprot id: H9UHQ9
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS14185
gene id: 889378:SPIAF_RS14185
uniprot id: H9UMZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

889378:SPIAF RS07945
gene id: 889378:SPIAF_RS07945
uniprot id: H9UJH4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

889378:SPIAF RS07670
gene id: 889378:SPIAF_RS07670
uniprot id: H9UJC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

889378:SPIAF RS14175
gene id: 889378:SPIAF_RS14175
uniprot id: H9UMY8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

889378:SPIAF RS02960
gene id: 889378:SPIAF_RS02960
uniprot id: H9UGP6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS03755
gene id: 889378:SPIAF_RS03755
uniprot id: H9UH52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

889378:SPIAF RS04145
gene id: 889378:SPIAF_RS04145
uniprot id: H9UHC9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

889378:SPIAF RS11325
gene id: 889378:SPIAF_RS11325
uniprot id: H9ULC6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

889378:SPIAF RS07335
gene id: 889378:SPIAF_RS07335
uniprot id: H9UJ55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasm
messages: Periplasmic flagellum

889378:SPIAF RS04370
gene id: 889378:SPIAF_RS04370
uniprot id: H1NDE6
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

889378:SPIAF RS06690
gene id: 889378:SPIAF_RS06690
uniprot id: H9UIS5
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

889378:SPIAF RS10495
gene id: 889378:SPIAF_RS10495
uniprot id: H9UKX4
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS12520
gene id: 889378:SPIAF_RS12520
uniprot id: H9UM13
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

889378:SPIAF RS02870
gene id: 889378:SPIAF_RS02870
uniprot id: H9UGM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

889378:SPIAF RS08305
gene id: 889378:SPIAF_RS08305
uniprot id: H9UJP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

889378:SPIAF RS11360
gene id: 889378:SPIAF_RS11360
uniprot id: H9ULD3
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS01900
gene id: 889378:SPIAF_RS01900
uniprot id: H9UG39
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

889378:SPIAF RS11195
gene id: 889378:SPIAF_RS11195
uniprot id: H9ULA3
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

889378:SPIAF RS07265
gene id: 889378:SPIAF_RS07265
uniprot id: H9UJ42
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS08370
gene id: 889378:SPIAF_RS08370
uniprot id: H9UJQ8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

889378:SPIAF RS12085
gene id: 889378:SPIAF_RS12085
uniprot id: H9ULS7
names: Similarity
messages: Belongs to the peptidase M29 family.

889378:SPIAF RS03615
gene id: 889378:SPIAF_RS03615
uniprot id: H9UH25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

889378:SPIAF RS01855
gene id: 889378:SPIAF_RS01855
uniprot id: H9UG30
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

889378:SPIAF RS11930
gene id: 889378:SPIAF_RS11930
uniprot id: H9ULP6
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

889378:SPIAF RS01000
gene id: 889378:SPIAF_RS01000
uniprot id: H9UFL5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

889378:SPIAF RS09240
gene id: 889378:SPIAF_RS09240
uniprot id: H9UK79
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

889378:SPIAF RS07955
gene id: 889378:SPIAF_RS07955
uniprot id: H9UJH6
names: Function
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

889378:SPIAF RS11865
gene id: 889378:SPIAF_RS11865
uniprot id: H9ULN2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

889378:SPIAF RS09035
gene id: 889378:SPIAF_RS09035
uniprot id: H9UK40
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

889378:SPIAF RS08560
gene id: 889378:SPIAF_RS08560
uniprot id: H9UJU6
names: Similarity
messages: Belongs to the Nth/MutY family.

889378:SPIAF RS10100
gene id: 889378:SPIAF_RS10100
uniprot id: H9UKP4
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS10575
gene id: 889378:SPIAF_RS10575
uniprot id: H9UKZ0
names: Similarity
messages: Belongs to the DEAD box helicase family.

889378:SPIAF RS04140
gene id: 889378:SPIAF_RS04140
uniprot id: H9UHC8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

889378:SPIAF RS05595
gene id: 889378:SPIAF_RS05595
uniprot id: H1NDE6
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

889378:SPIAF RS05345
gene id: 889378:SPIAF_RS05345
uniprot id: H9UI21
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS01250
gene id: 889378:SPIAF_RS01250
uniprot id: H9UFR4
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

889378:SPIAF RS09045
gene id: 889378:SPIAF_RS09045
uniprot id: H9UK42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

889378:SPIAF RS09675
gene id: 889378:SPIAF_RS09675
uniprot id: H9UKG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

889378:SPIAF RS09520
gene id: 889378:SPIAF_RS09520
uniprot id: H9UKD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

889378:SPIAF RS07600
gene id: 889378:SPIAF_RS07600
uniprot id: H9UJA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

889378:SPIAF RS03195
gene id: 889378:SPIAF_RS03195
uniprot id: H9UGU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

889378:SPIAF RS02675
gene id: 889378:SPIAF_RS02675
uniprot id: H9UGJ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

889378:SPIAF RS08610
gene id: 889378:SPIAF_RS08610
uniprot id: H9UJV6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

889378:SPIAF RS14045
gene id: 889378:SPIAF_RS14045
uniprot id: H9UMW2
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.

889378:SPIAF RS02360
gene id: 889378:SPIAF_RS02360
uniprot id: H9UGC7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

889378:SPIAF RS10395
gene id: 889378:SPIAF_RS10395
uniprot id: H9UKV3
names: Similarity
messages: Belongs to the FlgD family.

889378:SPIAF RS06885
gene id: 889378:SPIAF_RS06885
uniprot id: H9UIW6
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

889378:SPIAF RS13585
gene id: 889378:SPIAF_RS13585
uniprot id: H9UML9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

889378:SPIAF RS02315
gene id: 889378:SPIAF_RS02315
uniprot id: H9UGB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

889378:SPIAF RS03735
gene id: 889378:SPIAF_RS03735
uniprot id: H9UH48
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

889378:SPIAF RS01285
gene id: 889378:SPIAF_RS01285
uniprot id: H9UFS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

889378:SPIAF RS02765
gene id: 889378:SPIAF_RS02765
uniprot id: H9UGK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

889378:SPIAF RS01200
gene id: 889378:SPIAF_RS01200
uniprot id: H9UFQ4
names: Subcellular Location Annotation
messages: Cell inner membrane

889378:SPIAF RS12805
gene id: 889378:SPIAF_RS12805
uniprot id: H9UM70
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

889378:SPIAF RS11800
gene id: 889378:SPIAF_RS11800
uniprot id: H9ULL9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS02040
gene id: 889378:SPIAF_RS02040
uniprot id: H9UG65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

889378:SPIAF RS02235
gene id: 889378:SPIAF_RS02235
uniprot id: H9UGA2
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

889378:SPIAF RS12915
gene id: 889378:SPIAF_RS12915
uniprot id: H9UM88
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

889378:SPIAF RS14945
gene id: 889378:SPIAF_RS14945
uniprot id: H9UK86
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

889378:SPIAF RS01485
gene id: 889378:SPIAF_RS01485
uniprot id: H9UFW0
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

889378:SPIAF RS11140
gene id: 889378:SPIAF_RS11140
uniprot id: H9UL92
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

889378:SPIAF RS08190
gene id: 889378:SPIAF_RS08190
uniprot id: H9UJM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

889378:SPIAF RS08020
gene id: 889378:SPIAF_RS08020
uniprot id: H9UJI9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

889378:SPIAF RS09735
gene id: 889378:SPIAF_RS09735
uniprot id: H9UKH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

889378:SPIAF RS07550
gene id: 889378:SPIAF_RS07550
uniprot id: H9UJ96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

889378:SPIAF RS08345
gene id: 889378:SPIAF_RS08345
uniprot id: H9UJQ3
names: Similarity
messages: Belongs to the UPF0164 family.

889378:SPIAF RS01015
gene id: 889378:SPIAF_RS01015
uniprot id: H9UFL8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

889378:SPIAF RS09635
gene id: 889378:SPIAF_RS09635
uniprot id: H9UKF4
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS00175
gene id: 889378:SPIAF_RS00175
uniprot id: H9UF50
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS04970
gene id: 889378:SPIAF_RS04970
uniprot id: H9UHU3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

889378:SPIAF RS01010
gene id: 889378:SPIAF_RS01010
uniprot id: H9UFL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

889378:SPIAF RS14435
gene id: 889378:SPIAF_RS14435
uniprot id: H9UG42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

889378:SPIAF RS13805
gene id: 889378:SPIAF_RS13805
uniprot id: H9UMR3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

889378:SPIAF RS12780
gene id: 889378:SPIAF_RS12780
uniprot id: H9UM65
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

889378:SPIAF RS10265
gene id: 889378:SPIAF_RS10265
uniprot id: H9UKS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

889378:SPIAF RS04070
gene id: 889378:SPIAF_RS04070
uniprot id: H9UHB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

889378:SPIAF RS11250
gene id: 889378:SPIAF_RS11250
uniprot id: H1ND33
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

889378:SPIAF RS03370
gene id: 889378:SPIAF_RS03370
uniprot id: H9UGX7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

889378:SPIAF RS10110
gene id: 889378:SPIAF_RS10110
uniprot id: H9UKP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

889378:SPIAF RS08570
gene id: 889378:SPIAF_RS08570
uniprot id: H9UJU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

889378:SPIAF RS06295
gene id: 889378:SPIAF_RS06295
uniprot id: H9UIK3
names: Similarity
messages: Belongs to the acetyltransferase family. ArgA subfamily.

889378:SPIAF RS07570
gene id: 889378:SPIAF_RS07570
uniprot id: H9UJA0
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

889378:SPIAF RS06480
gene id: 889378:SPIAF_RS06480
uniprot id: H9UIP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

889378:SPIAF RS09525
gene id: 889378:SPIAF_RS09525
uniprot id: H9UKD2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

889378:SPIAF RS04800
gene id: 889378:SPIAF_RS04800
uniprot id: H9UHR1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

889378:SPIAF RS04715
gene id: 889378:SPIAF_RS04715
uniprot id: H9UHP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

889378:SPIAF RS07330
gene id: 889378:SPIAF_RS07330
uniprot id: H9UJ54
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

889378:SPIAF RS07940
gene id: 889378:SPIAF_RS07940
uniprot id: H9UJH3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

889378:SPIAF RS14950
gene id: 889378:SPIAF_RS14950
uniprot id: H9UK92
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

889378:SPIAF RS14250
gene id: 889378:SPIAF_RS14250
uniprot id: H9UMZ8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS09395
gene id: 889378:SPIAF_RS09395
uniprot id: H9UKA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

889378:SPIAF RS04755
gene id: 889378:SPIAF_RS04755
uniprot id: H9UHQ2
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS02115
gene id: 889378:SPIAF_RS02115
uniprot id: H9UG79
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

889378:SPIAF RS09640
gene id: 889378:SPIAF_RS09640
uniprot id: H9UKF5
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS10365
gene id: 889378:SPIAF_RS10365
uniprot id: H9UKU7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

889378:SPIAF RS03905
gene id: 889378:SPIAF_RS03905
uniprot id: H9UH82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

889378:SPIAF RS04205
gene id: 889378:SPIAF_RS04205
uniprot id: H9UHE0
names: Subcellular Location Annotation
messages: Cell inner membrane

889378:SPIAF RS07680
gene id: 889378:SPIAF_RS07680
uniprot id: H9UJC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

889378:SPIAF RS10475
gene id: 889378:SPIAF_RS10475
uniprot id: H9UKX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

889378:SPIAF RS01290
gene id: 889378:SPIAF_RS01290
uniprot id: H9UFS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

889378:SPIAF RS03180
gene id: 889378:SPIAF_RS03180
uniprot id: H9UGT9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

889378:SPIAF RS08480
gene id: 889378:SPIAF_RS08480
uniprot id: H9UJT0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

889378:SPIAF RS11350
gene id: 889378:SPIAF_RS11350
uniprot id: H9ULD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

889378:SPIAF RS09590
gene id: 889378:SPIAF_RS09590
uniprot id: H9UKE5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS13915
gene id: 889378:SPIAF_RS13915
uniprot id: H9UMT6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS01475
gene id: 889378:SPIAF_RS01475
uniprot id: H9UFV8
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS12850
gene id: 889378:SPIAF_RS12850
uniprot id: H9UM79
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

889378:SPIAF RS02305
gene id: 889378:SPIAF_RS02305
uniprot id: H9UGB6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS03975
gene id: 889378:SPIAF_RS03975
uniprot id: H9UH96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasmic flagellum

889378:SPIAF RS00050
gene id: 889378:SPIAF_RS00050
uniprot id: H9UF27
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

889378:SPIAF RS10360
gene id: 889378:SPIAF_RS10360
uniprot id: H9UKU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

889378:SPIAF RS02740
gene id: 889378:SPIAF_RS02740
uniprot id: H9UGK1
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

889378:SPIAF RS11975
gene id: 889378:SPIAF_RS11975
uniprot id: H9ULQ5
names: Similarity
messages: Belongs to the class II ribonucleoside-triphosphate reductase family.

889378:SPIAF RS13190
gene id: 889378:SPIAF_RS13190
uniprot id: H9UME2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Tetramer of two alpha and two beta subunits.

889378:SPIAF RS10480
gene id: 889378:SPIAF_RS10480
uniprot id: H9UKX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

889378:SPIAF RS14145
gene id: 889378:SPIAF_RS14145
uniprot id: H9UMY2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

889378:SPIAF RS08030
gene id: 889378:SPIAF_RS08030
uniprot id: H9UJJ1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

889378:SPIAF RS01785
gene id: 889378:SPIAF_RS01785
uniprot id: H9UG15
names: Similarity
messages: Belongs to the ArsC family.

889378:SPIAF RS08115
gene id: 889378:SPIAF_RS08115
uniprot id: H9UJK8
names: Similarity
messages: Belongs to the V-ATPase D subunit family.

889378:SPIAF RS05210
gene id: 889378:SPIAF_RS05210
uniprot id: H9UHZ3
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS01020
gene id: 889378:SPIAF_RS01020
uniprot id: H9UFL9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

889378:SPIAF RS10370
gene id: 889378:SPIAF_RS10370
uniprot id: H9UKU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

889378:SPIAF RS09585
gene id: 889378:SPIAF_RS09585
uniprot id: H9UKE4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL31 family.

889378:SPIAF RS07650
gene id: 889378:SPIAF_RS07650
uniprot id: H9UJB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

889378:SPIAF RS00055
gene id: 889378:SPIAF_RS00055
uniprot id: H9UF28
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

889378:SPIAF RS12625
gene id: 889378:SPIAF_RS12625
uniprot id: H9UM34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

889378:SPIAF RS07160
gene id: 889378:SPIAF_RS07160
uniprot id: H9UJ22
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

889378:SPIAF RS01760
gene id: 889378:SPIAF_RS01760
uniprot id: H9UG10
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

889378:SPIAF RS00385
gene id: 889378:SPIAF_RS00385
uniprot id: H9UF92
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

889378:SPIAF RS06435
gene id: 889378:SPIAF_RS06435
uniprot id: H9UIN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

889378:SPIAF RS02355
gene id: 889378:SPIAF_RS02355
uniprot id: H9UGC6
names: Similarity
messages: Belongs to the aldose epimerase family.

889378:SPIAF RS07555
gene id: 889378:SPIAF_RS07555
uniprot id: H9UJ97
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS04090
gene id: 889378:SPIAF_RS04090
uniprot id: H9UHB9
names: Subcellular Location Annotation
messages: Periplasmic flagellum

889378:SPIAF RS03140
gene id: 889378:SPIAF_RS03140
uniprot id: H9UGT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

889378:SPIAF RS15855
gene id: 889378:SPIAF_RS15855
uniprot id: H9UGC2
names: Subcellular Location Annotation
messages: Nucleus

889378:SPIAF RS04820
gene id: 889378:SPIAF_RS04820
uniprot id: H9UHR5
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

889378:SPIAF RS09830
gene id: 889378:SPIAF_RS09830
uniprot id: H9UKJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

889378:SPIAF RS13675
gene id: 889378:SPIAF_RS13675
uniprot id: H9UMN7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

889378:SPIAF RS05970
gene id: 889378:SPIAF_RS05970
uniprot id: H9UIE0
names: Subcellular Location Annotation
messages: Nucleus

889378:SPIAF RS02810
gene id: 889378:SPIAF_RS02810
uniprot id: H9UGL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

889378:SPIAF RS13305
gene id: 889378:SPIAF_RS13305
uniprot id: H9UMG5
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS00790
gene id: 889378:SPIAF_RS00790
uniprot id: H9UFH3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

889378:SPIAF RS08640
gene id: 889378:SPIAF_RS08640
uniprot id: H9UJW2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

889378:SPIAF RS08590
gene id: 889378:SPIAF_RS08590
uniprot id: H9UJV2
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

889378:SPIAF RS02845
gene id: 889378:SPIAF_RS02845
uniprot id: H9UGM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

889378:SPIAF RS07275
gene id: 889378:SPIAF_RS07275
uniprot id: H9UJ44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

889378:SPIAF RS03310
gene id: 889378:SPIAF_RS03310
uniprot id: H9UGW5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

889378:SPIAF RS07220
gene id: 889378:SPIAF_RS07220
uniprot id: H9UJ34
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

889378:SPIAF RS04525
gene id: 889378:SPIAF_RS04525
uniprot id: H9UHK7
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS09360
gene id: 889378:SPIAF_RS09360
uniprot id: H9UKA2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

889378:SPIAF RS12290
gene id: 889378:SPIAF_RS12290
uniprot id: H9ULW8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

889378:SPIAF RS03460
gene id: 889378:SPIAF_RS03460
uniprot id: H9UGZ5
names: Similarity
messages: Belongs to the disproportionating enzyme family.

889378:SPIAF RS11520
gene id: 889378:SPIAF_RS11520
uniprot id: H9ULG4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

889378:SPIAF RS10380
gene id: 889378:SPIAF_RS10380
uniprot id: H9UKV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

889378:SPIAF RS13285
gene id: 889378:SPIAF_RS13285
uniprot id: H9UMG1
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

889378:SPIAF RS10520
gene id: 889378:SPIAF_RS10520
uniprot id: H9UKX9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

889378:SPIAF RS07640
gene id: 889378:SPIAF_RS07640
uniprot id: H9UJB4
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

889378:SPIAF RS12645
gene id: 889378:SPIAF_RS12645
uniprot id: H9UM38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

889378:SPIAF RS08655
gene id: 889378:SPIAF_RS08655
uniprot id: H9UJW5
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

889378:SPIAF RS09375
gene id: 889378:SPIAF_RS09375
uniprot id: H9UKA5
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

889378:SPIAF RS03980
gene id: 889378:SPIAF_RS03980
uniprot id: H9UH97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

889378:SPIAF RS13680
gene id: 889378:SPIAF_RS13680
uniprot id: H9UMN8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

889378:SPIAF RS02900
gene id: 889378:SPIAF_RS02900
uniprot id: H9UGN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

889378:SPIAF RS13425
gene id: 889378:SPIAF_RS13425
uniprot id: H9UMI8
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

889378:SPIAF RS06810
gene id: 889378:SPIAF_RS06810
uniprot id: H1NDE6
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

889378:SPIAF RS10925
gene id: 889378:SPIAF_RS10925
uniprot id: H9UL49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

889378:SPIAF RS12470
gene id: 889378:SPIAF_RS12470
uniprot id: H9UM03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

889378:SPIAF RS02155
gene id: 889378:SPIAF_RS02155
uniprot id: H9UG87
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS13645
gene id: 889378:SPIAF_RS13645
uniprot id: H9UMN1
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

889378:SPIAF RS12710
gene id: 889378:SPIAF_RS12710
uniprot id: H9UM51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

889378:SPIAF RS13400
gene id: 889378:SPIAF_RS13400
uniprot id: H9UMI3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS07995
gene id: 889378:SPIAF_RS07995
uniprot id: H9UJI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

889378:SPIAF RS11550
gene id: 889378:SPIAF_RS11550
uniprot id: H9ULH0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

889378:SPIAF RS01825
gene id: 889378:SPIAF_RS01825
uniprot id: H9UG24
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS04450
gene id: 889378:SPIAF_RS04450
uniprot id: H9UHJ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved Asp active site.

889378:SPIAF RS07950
gene id: 889378:SPIAF_RS07950
uniprot id: H9UJH5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

889378:SPIAF RS02615
gene id: 889378:SPIAF_RS02615
uniprot id: H9UGH8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

889378:SPIAF RS09295
gene id: 889378:SPIAF_RS09295
uniprot id: H9UK89
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

889378:SPIAF RS02655
gene id: 889378:SPIAF_RS02655
uniprot id: H9UGI6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

889378:SPIAF RS07005
gene id: 889378:SPIAF_RS07005
uniprot id: H9UIZ1
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

889378:SPIAF RS12960
gene id: 889378:SPIAF_RS12960
uniprot id: H9UM96
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

889378:SPIAF RS12825
gene id: 889378:SPIAF_RS12825
uniprot id: H9UM74
names: Similarity
messages: Belongs to the peptidase M16 family.

889378:SPIAF RS03865
gene id: 889378:SPIAF_RS03865
uniprot id: H9UH74
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

889378:SPIAF RS13955
gene id: 889378:SPIAF_RS13955
uniprot id: H9UMU4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

889378:SPIAF RS11725
gene id: 889378:SPIAF_RS11725
uniprot id: H9ULK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

889378:SPIAF RS12475
gene id: 889378:SPIAF_RS12475
uniprot id: H9UM04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

889378:SPIAF RS00940
gene id: 889378:SPIAF_RS00940
uniprot id: H9UFK3
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS02715
gene id: 889378:SPIAF_RS02715
uniprot id: H9UGJ8
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

889378:SPIAF RS09270
gene id: 889378:SPIAF_RS09270
uniprot id: H9UK85
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

889378:SPIAF RS01830
gene id: 889378:SPIAF_RS01830
uniprot id: H9UG25
names: Function
names: Similarity
messages: Belongs to the ferredoxin thioredoxin reductase beta subunit family.
messages: Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.

889378:SPIAF RS10755
gene id: 889378:SPIAF_RS10755
uniprot id: H9UL15
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

889378:SPIAF RS11515
gene id: 889378:SPIAF_RS11515
uniprot id: H9ULG3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

889378:SPIAF RS03170
gene id: 889378:SPIAF_RS03170
uniprot id: H9UGT7
names: Subcellular Location Annotation
messages: Periplasm

889378:SPIAF RS14800
gene id: 889378:SPIAF_RS14800
uniprot id: H9UIS0
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS13895
gene id: 889378:SPIAF_RS13895
uniprot id: H9UMT2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

889378:SPIAF RS02755
gene id: 889378:SPIAF_RS02755
uniprot id: H9UGK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

889378:SPIAF RS05845
gene id: 889378:SPIAF_RS05845
uniprot id: H9UIB6
names: Similarity
messages: Belongs to the UPF0178 family.

889378:SPIAF RS10485
gene id: 889378:SPIAF_RS10485
uniprot id: H9UKX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

889378:SPIAF RS03440
gene id: 889378:SPIAF_RS03440
uniprot id: H9UGZ1
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

889378:SPIAF RS09260
gene id: 889378:SPIAF_RS09260
uniprot id: H9UK83
names: Similarity
messages: Belongs to the peptidase S1C family.

889378:SPIAF RS11580
gene id: 889378:SPIAF_RS11580
uniprot id: H9ULH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

889378:SPIAF RS11020
gene id: 889378:SPIAF_RS11020
uniprot id: H9UL68
names: Subcellular Location Annotation
messages: Cytoplasm

889378:SPIAF RS13720
gene id: 889378:SPIAF_RS13720
uniprot id: H9UMP6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS00965
gene id: 889378:SPIAF_RS00965
uniprot id: H9UFK8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

889378:SPIAF RS04115
gene id: 889378:SPIAF_RS04115
uniprot id: H9UHC3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

889378:SPIAF RS02685
gene id: 889378:SPIAF_RS02685
uniprot id: H9UGJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

889378:SPIAF RS09305
gene id: 889378:SPIAF_RS09305
uniprot id: H9UK91
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

889378:SPIAF RS06330
gene id: 889378:SPIAF_RS06330
uniprot id: H9UIL0
names: Similarity
messages: Belongs to the bacterial glucokinase family.

889378:SPIAF RS10270
gene id: 889378:SPIAF_RS10270
uniprot id: H9UKS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

889378:SPIAF RS04030
gene id: 889378:SPIAF_RS04030
uniprot id: H9UHA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasm
messages: Periplasmic flagellum

889378:SPIAF RS05865
gene id: 889378:SPIAF_RS05865
uniprot id: H9UIC0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

889378:SPIAF RS00365
gene id: 889378:SPIAF_RS00365
uniprot id: H9UF88
names: Similarity
messages: Belongs to the YjiK family.

889378:SPIAF RS01795
gene id: 889378:SPIAF_RS01795
uniprot id: H9UG17
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

889378:SPIAF RS04635
gene id: 889378:SPIAF_RS04635
uniprot id: H9UHM8
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

889378:SPIAF RS06570
gene id: 889378:SPIAF_RS06570
uniprot id: H9UIQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

889378:SPIAF RS02150
gene id: 889378:SPIAF_RS02150
uniprot id: H9UG86
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS05335
gene id: 889378:SPIAF_RS05335
uniprot id: H9UI19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

889378:SPIAF RS09355
gene id: 889378:SPIAF_RS09355
uniprot id: H9UKA1
names: Similarity
messages: Belongs to the glutamate synthase family.

889378:SPIAF RS07295
gene id: 889378:SPIAF_RS07295
uniprot id: H9UJ47
names: Similarity
messages: Belongs to the peptidase M18 family.

889378:SPIAF RS07595
gene id: 889378:SPIAF_RS07595
uniprot id: H9UJA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

889378:SPIAF RS12000
gene id: 889378:SPIAF_RS12000
uniprot id: H9ULR0
names: Similarity
messages: Belongs to the fructosamine kinase family.

889378:SPIAF RS10345
gene id: 889378:SPIAF_RS10345
uniprot id: U3GJS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

889378:SPIAF RS06550
gene id: 889378:SPIAF_RS06550
uniprot id: H9UIQ3
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

889378:SPIAF RS13780
gene id: 889378:SPIAF_RS13780
uniprot id: H9UMQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

889378:SPIAF RS01780
gene id: 889378:SPIAF_RS01780
uniprot id: H9UG14
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

889378:SPIAF RS14135
gene id: 889378:SPIAF_RS14135
uniprot id: H9UMY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

889378:SPIAF RS11355
gene id: 889378:SPIAF_RS11355
uniprot id: H9ULD2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS13810
gene id: 889378:SPIAF_RS13810
uniprot id: H9UMR4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

889378:SPIAF RS05935
gene id: 889378:SPIAF_RS05935
uniprot id: H9UID4
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

889378:SPIAF RS06490
gene id: 889378:SPIAF_RS06490
uniprot id: H1NDE6
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

889378:SPIAF RS08460
gene id: 889378:SPIAF_RS08460
uniprot id: H9UJS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

889378:SPIAF RS01390
gene id: 889378:SPIAF_RS01390
uniprot id: H9UFU2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

889378:SPIAF RS00835
gene id: 889378:SPIAF_RS00835
uniprot id: H9UFI2
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

889378:SPIAF RS11345
gene id: 889378:SPIAF_RS11345
uniprot id: H9ULD0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

889378:SPIAF RS04675
gene id: 889378:SPIAF_RS04675
uniprot id: H9UHN6
names: Subcellular Location Annotation
messages: Periplasm

889378:SPIAF RS09615
gene id: 889378:SPIAF_RS09615
uniprot id: H9UKF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

889378:SPIAF RS04025
gene id: 889378:SPIAF_RS04025
uniprot id: H9UHA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasm
messages: Periplasmic flagellum

889378:SPIAF RS00800
gene id: 889378:SPIAF_RS00800
uniprot id: H9UFH5
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS14245
gene id: 889378:SPIAF_RS14245
uniprot id: H9UMZ7
names: Similarity
messages: Belongs to the IMPACT family.

889378:SPIAF RS05615
gene id: 889378:SPIAF_RS05615
uniprot id: H9UI74
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

889378:SPIAF RS03015
gene id: 889378:SPIAF_RS03015
uniprot id: H9UGQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

889378:SPIAF RS05555
gene id: 889378:SPIAF_RS05555
uniprot id: H9UI63
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

889378:SPIAF RS05790
gene id: 889378:SPIAF_RS05790
uniprot id: H9UIA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

889378:SPIAF RS08915
gene id: 889378:SPIAF_RS08915
uniprot id: H9UK16
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

889378:SPIAF RS02775
gene id: 889378:SPIAF_RS02775
uniprot id: H9UGK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

889378:SPIAF RS01885
gene id: 889378:SPIAF_RS01885
uniprot id: H9UG36
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

889378:SPIAF RS10015
gene id: 889378:SPIAF_RS10015
uniprot id: H9UKM8
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

889378:SPIAF RS06650
gene id: 889378:SPIAF_RS06650
uniprot id: H9UIR8
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

889378:SPIAF RS03000
gene id: 889378:SPIAF_RS03000
uniprot id: H9UGQ3
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Homodimer.

889378:SPIAF RS02815
gene id: 889378:SPIAF_RS02815
uniprot id: H9UGL6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

889378:SPIAF RS08210
gene id: 889378:SPIAF_RS08210
uniprot id: H9UJM7
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

889378:SPIAF RS07010
gene id: 889378:SPIAF_RS07010
uniprot id: H9UIZ2
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.

889378:SPIAF RS01385
gene id: 889378:SPIAF_RS01385
uniprot id: H9UFU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

889378:SPIAF RS10720
gene id: 889378:SPIAF_RS10720
uniprot id: H9UL08
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

889378:SPIAF RS11150
gene id: 889378:SPIAF_RS11150
uniprot id: H9UL94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

889378:SPIAF RS11675
gene id: 889378:SPIAF_RS11675
uniprot id: H9ULJ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

889378:SPIAF RS00695
gene id: 889378:SPIAF_RS00695
uniprot id: H9UFF3
names: Similarity
messages: Belongs to the WrbA family.

889378:SPIAF RS12745
gene id: 889378:SPIAF_RS12745
uniprot id: H9UM58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

889378:SPIAF RS03795
gene id: 889378:SPIAF_RS03795
uniprot id: H9UH60
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS12730
gene id: 889378:SPIAF_RS12730
uniprot id: H9UM55
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS12760
gene id: 889378:SPIAF_RS12760
uniprot id: H9UM61
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

889378:SPIAF RS00340
gene id: 889378:SPIAF_RS00340
uniprot id: H9UF83
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS08065
gene id: 889378:SPIAF_RS08065
uniprot id: H9UJJ8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

889378:SPIAF RS03985
gene id: 889378:SPIAF_RS03985
uniprot id: H9UH98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

889378:SPIAF RS08690
gene id: 889378:SPIAF_RS08690
uniprot id: H9UJX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

889378:SPIAF RS07015
gene id: 889378:SPIAF_RS07015
uniprot id: H9UIZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to a coenzyme A (CoA).
messages: Monomer.

889378:SPIAF RS11730
gene id: 889378:SPIAF_RS11730
uniprot id: H9ULK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

889378:SPIAF RS12375
gene id: 889378:SPIAF_RS12375
uniprot id: H9ULY5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

889378:SPIAF RS00955
gene id: 889378:SPIAF_RS00955
uniprot id: H9UFK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

889378:SPIAF RS07110
gene id: 889378:SPIAF_RS07110
uniprot id: H9UJ12
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

889378:SPIAF RS09515
gene id: 889378:SPIAF_RS09515
uniprot id: H9UKD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

889378:SPIAF RS00435
gene id: 889378:SPIAF_RS00435
uniprot id: H9UFA2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

889378:SPIAF RS04840
gene id: 889378:SPIAF_RS04840
uniprot id: H9UHR8
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

889378:SPIAF RS10845
gene id: 889378:SPIAF_RS10845
uniprot id: H9UL32
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS02910
gene id: 889378:SPIAF_RS02910
uniprot id: H9UGN6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

889378:SPIAF RS05510
gene id: 889378:SPIAF_RS05510
uniprot id: H9UI54
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS07300
gene id: 889378:SPIAF_RS07300
uniprot id: H9UJ48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

889378:SPIAF RS09140
gene id: 889378:SPIAF_RS09140
uniprot id: H9UK61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

889378:SPIAF RS05840
gene id: 889378:SPIAF_RS05840
uniprot id: H9UIB5
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

889378:SPIAF RS04340
gene id: 889378:SPIAF_RS04340
uniprot id: H9UHG7
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

889378:SPIAF RS11045
gene id: 889378:SPIAF_RS11045
uniprot id: H9UL73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm

889378:SPIAF RS15115
gene id: 889378:SPIAF_RS15115
uniprot id: H9ULP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

889378:SPIAF RS02940
gene id: 889378:SPIAF_RS02940
uniprot id: H9UGP2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

889378:SPIAF RS12880
gene id: 889378:SPIAF_RS12880
uniprot id: H9UM81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

889378:SPIAF RS10560
gene id: 889378:SPIAF_RS10560
uniprot id: H9UKY7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

889378:SPIAF RS10445
gene id: 889378:SPIAF_RS10445
uniprot id: H9UKW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

889378:SPIAF RS06275
gene id: 889378:SPIAF_RS06275
uniprot id: H9UIJ9
names: Similarity
messages: Belongs to the LOG family.

889378:SPIAF RS08505
gene id: 889378:SPIAF_RS08505
uniprot id: H9UJT5
names: Similarity
messages: Belongs to the DEAD box helicase family.

889378:SPIAF RS12040
gene id: 889378:SPIAF_RS12040
uniprot id: H9ULR8
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

889378:SPIAF RS09850
gene id: 889378:SPIAF_RS09850
uniprot id: H9UKJ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

889378:SPIAF RS06930
gene id: 889378:SPIAF_RS06930
uniprot id: H9UIX6
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

889378:SPIAF RS02745
gene id: 889378:SPIAF_RS02745
uniprot id: H9UGK2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

889378:SPIAF RS05655
gene id: 889378:SPIAF_RS05655
uniprot id: H9UI82
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

889378:SPIAF RS04345
gene id: 889378:SPIAF_RS04345
uniprot id: H1ND33
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

889378:SPIAF RS09050
gene id: 889378:SPIAF_RS09050
uniprot id: H9UK43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

889378:SPIAF RS09935
gene id: 889378:SPIAF_RS09935
uniprot id: H9UKL3
names: Similarity
messages: Belongs to the BMP lipoprotein family.

889378:SPIAF RS10250
gene id: 889378:SPIAF_RS10250
uniprot id: H9UKS3
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

889378:SPIAF RS02735
gene id: 889378:SPIAF_RS02735
uniprot id: H9UGK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

889378:SPIAF RS05505
gene id: 889378:SPIAF_RS05505
uniprot id: H9UI53
names: Similarity
messages: Belongs to the UPF0237 family.

889378:SPIAF RS13630
gene id: 889378:SPIAF_RS13630
uniprot id: H9UMM8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

889378:SPIAF RS00635
gene id: 889378:SPIAF_RS00635
uniprot id: H9UFE1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

889378:SPIAF RS00960
gene id: 889378:SPIAF_RS00960
uniprot id: H9UFK7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS07625
gene id: 889378:SPIAF_RS07625
uniprot id: H9UJB1
names: Similarity
messages: Belongs to the Skp family.

889378:SPIAF RS14515
gene id: 889378:SPIAF_RS14515
uniprot id: H9UGV8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

889378:SPIAF RS08200
gene id: 889378:SPIAF_RS08200
uniprot id: H9UJM5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

889378:SPIAF RS03485
gene id: 889378:SPIAF_RS03485
uniprot id: H9UH00
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

889378:SPIAF RS09500
gene id: 889378:SPIAF_RS09500
uniprot id: H9UKC8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

889378:SPIAF RS13125
gene id: 889378:SPIAF_RS13125
uniprot id: H9UMC9
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

889378:SPIAF RS01155
gene id: 889378:SPIAF_RS01155
uniprot id: H9UFP6
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

889378:SPIAF RS02380
gene id: 889378:SPIAF_RS02380
uniprot id: H9UGD1
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

889378:SPIAF RS09040
gene id: 889378:SPIAF_RS09040
uniprot id: H9UK41
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS00865
gene id: 889378:SPIAF_RS00865
uniprot id: H9UFI8
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS03810
gene id: 889378:SPIAF_RS03810
uniprot id: H1NDE6
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

889378:SPIAF RS10425
gene id: 889378:SPIAF_RS10425
uniprot id: H9UKV9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

889378:SPIAF RS12295
gene id: 889378:SPIAF_RS12295
uniprot id: H9ULW9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

889378:SPIAF RS02930
gene id: 889378:SPIAF_RS02930
uniprot id: H9UGP0
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

889378:SPIAF RS05045
gene id: 889378:SPIAF_RS05045
uniprot id: H1ND33
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

889378:SPIAF RS05940
gene id: 889378:SPIAF_RS05940
uniprot id: H9UID5
names: Similarity
messages: Belongs to the glutamine synthetase family.

889378:SPIAF RS06685
gene id: 889378:SPIAF_RS06685
uniprot id: H9UIS4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

889378:SPIAF RS12310
gene id: 889378:SPIAF_RS12310
uniprot id: H9ULX2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS09580
gene id: 889378:SPIAF_RS09580
uniprot id: H9UKE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

889378:SPIAF RS09950
gene id: 889378:SPIAF_RS09950
uniprot id: H9UKL6
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS13970
gene id: 889378:SPIAF_RS13970
uniprot id: H9UMU7
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

889378:SPIAF RS09315
gene id: 889378:SPIAF_RS09315
uniprot id: H9UK93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

889378:SPIAF RS00160
gene id: 889378:SPIAF_RS00160
uniprot id: H9UF47
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

889378:SPIAF RS05170
gene id: 889378:SPIAF_RS05170
uniprot id: H9UHY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

889378:SPIAF RS13590
gene id: 889378:SPIAF_RS13590
uniprot id: H9UMM0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS14475
gene id: 889378:SPIAF_RS14475
uniprot id: H9UGD7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS10190
gene id: 889378:SPIAF_RS10190
uniprot id: H9UKR2
names: Similarity
messages: Belongs to the DtxR/MntR family.

889378:SPIAF RS04150
gene id: 889378:SPIAF_RS04150
uniprot id: H9UHD0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

889378:SPIAF RS14240
gene id: 889378:SPIAF_RS14240
uniprot id: H9UMZ6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

889378:SPIAF RS02770
gene id: 889378:SPIAF_RS02770
uniprot id: H9UGK7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

889378:SPIAF RS00045
gene id: 889378:SPIAF_RS00045
uniprot id: H9UF26
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

889378:SPIAF RS11585
gene id: 889378:SPIAF_RS11585
uniprot id: H9ULH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

889378:SPIAF RS10525
gene id: 889378:SPIAF_RS10525
uniprot id: H9UKY0
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

889378:SPIAF RS09430
gene id: 889378:SPIAF_RS09430
uniprot id: H9UKB5
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

889378:SPIAF RS13035
gene id: 889378:SPIAF_RS13035
uniprot id: H9UMB1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

889378:SPIAF RS08215
gene id: 889378:SPIAF_RS08215
uniprot id: U3GJS5
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

889378:SPIAF RS09425
gene id: 889378:SPIAF_RS09425
uniprot id: H9UKB4
names: Similarity
names: Subunit
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

889378:SPIAF RS07035
gene id: 889378:SPIAF_RS07035
uniprot id: H9UIZ7
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS08405
gene id: 889378:SPIAF_RS08405
uniprot id: H9UJR5
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

889378:SPIAF RS05965
gene id: 889378:SPIAF_RS05965
uniprot id: H9UID9
names: Similarity
messages: Belongs to the peptidase S49 family.

889378:SPIAF RS03855
gene id: 889378:SPIAF_RS03855
uniprot id: H1ND33
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

889378:SPIAF RS04880
gene id: 889378:SPIAF_RS04880
uniprot id: H9UHS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

889378:SPIAF RS05015
gene id: 889378:SPIAF_RS05015
uniprot id: H1ND33
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

889378:SPIAF RS08620
gene id: 889378:SPIAF_RS08620
uniprot id: H9UJV8
names: Subcellular Location Annotation
messages: Nucleus

889378:SPIAF RS00405
gene id: 889378:SPIAF_RS00405
uniprot id: H9UF96
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

889378:SPIAF RS13825
gene id: 889378:SPIAF_RS13825
uniprot id: H9UMR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

889378:SPIAF RS14195
gene id: 889378:SPIAF_RS14195
uniprot id: H9UMZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

889378:SPIAF RS12815
gene id: 889378:SPIAF_RS12815
uniprot id: H9UM72
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

889378:SPIAF RS11025
gene id: 889378:SPIAF_RS11025
uniprot id: H9UL69
names: Similarity
messages: Belongs to the YggT family.

889378:SPIAF RS04745
gene id: 889378:SPIAF_RS04745
uniprot id: H9UHQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

889378:SPIAF RS10165
gene id: 889378:SPIAF_RS10165
uniprot id: H9UKQ7
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

889378:SPIAF RS10170
gene id: 889378:SPIAF_RS10170
uniprot id: H9UKQ8
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

889378:SPIAF RS12485
gene id: 889378:SPIAF_RS12485
uniprot id: H9UM06
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

889378:SPIAF RS13470
gene id: 889378:SPIAF_RS13470
uniprot id: H9UMJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

889378:SPIAF RS07665
gene id: 889378:SPIAF_RS07665
uniprot id: H9UJB9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

889378:SPIAF RS08550
gene id: 889378:SPIAF_RS08550
uniprot id: H9UJU4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

889378:SPIAF RS08675
gene id: 889378:SPIAF_RS08675
uniprot id: H9UJW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

889378:SPIAF RS10240
gene id: 889378:SPIAF_RS10240
uniprot id: H9UKS1
names: Similarity
messages: Belongs to the UPF0758 family.

889378:SPIAF RS03150
gene id: 889378:SPIAF_RS03150
uniprot id: H9UGT3
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

889378:SPIAF RS05925
gene id: 889378:SPIAF_RS05925
uniprot id: H9UID2
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

889378:SPIAF RS02010
gene id: 889378:SPIAF_RS02010
uniprot id: H9UG59
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

889378:SPIAF RS13350
gene id: 889378:SPIAF_RS13350
uniprot id: H9UMH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

889378:SPIAF RS14010
gene id: 889378:SPIAF_RS14010
uniprot id: H9UMV5
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

889378:SPIAF RS09730
gene id: 889378:SPIAF_RS09730
uniprot id: H9UKH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

889378:SPIAF RS12895
gene id: 889378:SPIAF_RS12895
uniprot id: H9UM84
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

889378:SPIAF RS12580
gene id: 889378:SPIAF_RS12580
uniprot id: H9UM25
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

889378:SPIAF RS09915
gene id: 889378:SPIAF_RS09915
uniprot id: H9UKK9
names: Function
names: Subunit
messages: Interacts with sigma-54.
messages: Required for activation of most nif operons, which are directly involved in nitrogen fixation.

889378:SPIAF RS05410
gene id: 889378:SPIAF_RS05410
uniprot id: H9UI34
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

889378:SPIAF RS02135
gene id: 889378:SPIAF_RS02135
uniprot id: H9UG83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

889378:SPIAF RS02865
gene id: 889378:SPIAF_RS02865
uniprot id: H9UGM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

889378:SPIAF RS08105
gene id: 889378:SPIAF_RS08105
uniprot id: H9UJK6
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS05915
gene id: 889378:SPIAF_RS05915
uniprot id: H9UID0
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase 20 family.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the trehalose phosphatase family.

889378:SPIAF RS03540
gene id: 889378:SPIAF_RS03540
uniprot id: H9UH11
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

889378:SPIAF RS10955
gene id: 889378:SPIAF_RS10955
uniprot id: H9UL55
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

889378:SPIAF RS04015
gene id: 889378:SPIAF_RS04015
uniprot id: H9UHA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Periplasm
messages: Periplasmic flagellum
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.

889378:SPIAF RS12615
gene id: 889378:SPIAF_RS12615
uniprot id: H9UM32
names: Similarity
messages: Belongs to the thioredoxin family.

889378:SPIAF RS06195
gene id: 889378:SPIAF_RS06195
uniprot id: H9UII3
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS13250
gene id: 889378:SPIAF_RS13250
uniprot id: H9UMF4
names: Similarity
messages: Belongs to the sigma-54 factor family.

889378:SPIAF RS02905
gene id: 889378:SPIAF_RS02905
uniprot id: H9UGN5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

889378:SPIAF RS13165
gene id: 889378:SPIAF_RS13165
uniprot id: H9UMD7
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

889378:SPIAF RS02565
gene id: 889378:SPIAF_RS02565
uniprot id: H9UGG8
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS09805
gene id: 889378:SPIAF_RS09805
uniprot id: H9UKI8
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS13750
gene id: 889378:SPIAF_RS13750
uniprot id: H9UMQ2
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

889378:SPIAF RS07420
gene id: 889378:SPIAF_RS07420
uniprot id: H9UJ70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS14150
gene id: 889378:SPIAF_RS14150
uniprot id: H9UMY3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

889378:SPIAF RS08490
gene id: 889378:SPIAF_RS08490
uniprot id: H9UJT2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

889378:SPIAF RS02140
gene id: 889378:SPIAF_RS02140
uniprot id: H9UG84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

889378:SPIAF RS10915
gene id: 889378:SPIAF_RS10915
uniprot id: H9UL47
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

889378:SPIAF RS10950
gene id: 889378:SPIAF_RS10950
uniprot id: H9UL54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

889378:SPIAF RS13410
gene id: 889378:SPIAF_RS13410
uniprot id: H9UMI5
names: Similarity
messages: Belongs to the citrate synthase family.

889378:SPIAF RS03345
gene id: 889378:SPIAF_RS03345
uniprot id: H9UGX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

889378:SPIAF RS13185
gene id: 889378:SPIAF_RS13185
uniprot id: H9UME1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

889378:SPIAF RS12140
gene id: 889378:SPIAF_RS12140
uniprot id: H9ULT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

889378:SPIAF RS11455
gene id: 889378:SPIAF_RS11455
uniprot id: H9ULF1
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS03205
gene id: 889378:SPIAF_RS03205
uniprot id: H9UGU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

889378:SPIAF RS05980
gene id: 889378:SPIAF_RS05980
uniprot id: H9UIE2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

889378:SPIAF RS05200
gene id: 889378:SPIAF_RS05200
uniprot id: H9UHZ1
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

889378:SPIAF RS11145
gene id: 889378:SPIAF_RS11145
uniprot id: H9UL93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

889378:SPIAF RS05975
gene id: 889378:SPIAF_RS05975
uniprot id: H9UIE1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

889378:SPIAF RS01710
gene id: 889378:SPIAF_RS01710
uniprot id: H9UG01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

889378:SPIAF RS09965
gene id: 889378:SPIAF_RS09965
uniprot id: H9UKL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

889378:SPIAF RS00900
gene id: 889378:SPIAF_RS00900
uniprot id: H9UFJ5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

889378:SPIAF RS02825
gene id: 889378:SPIAF_RS02825
uniprot id: H9UGL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

889378:SPIAF RS08375
gene id: 889378:SPIAF_RS08375
uniprot id: H9UJQ9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

889378:SPIAF RS14410
gene id: 889378:SPIAF_RS14410
uniprot id: H9UFW7
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

889378:SPIAF RS07255
gene id: 889378:SPIAF_RS07255
uniprot id: H9UJ40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

889378:SPIAF RS10325
gene id: 889378:SPIAF_RS10325
uniprot id: U3GJI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

889378:SPIAF RS09705
gene id: 889378:SPIAF_RS09705
uniprot id: H9UKG8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

889378:SPIAF RS01205
gene id: 889378:SPIAF_RS01205
uniprot id: H9UFQ5
names: Similarity
messages: Belongs to the Dps family.

889378:SPIAF RS07400
gene id: 889378:SPIAF_RS07400
uniprot id: H9UJ66
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

889378:SPIAF RS00080
gene id: 889378:SPIAF_RS00080
uniprot id: H9UIV3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

889378:SPIAF RS10690
gene id: 889378:SPIAF_RS10690
uniprot id: H9UL03
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

889378:SPIAF RS02325
gene id: 889378:SPIAF_RS02325
uniprot id: H9UGC0
names: Similarity
messages: Belongs to the SAICAR synthetase family.

889378:SPIAF RS05415
gene id: 889378:SPIAF_RS05415
uniprot id: H9UI35
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

889378:SPIAF RS05785
gene id: 889378:SPIAF_RS05785
uniprot id: H9UIA4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

889378:SPIAF RS10785
gene id: 889378:SPIAF_RS10785
uniprot id: H9UL20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

889378:SPIAF RS00280
gene id: 889378:SPIAF_RS00280
uniprot id: H9UF71
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS06880
gene id: 889378:SPIAF_RS06880
uniprot id: H9UIW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

889378:SPIAF RS13940
gene id: 889378:SPIAF_RS13940
uniprot id: H9UMU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

889378:SPIAF RS06835
gene id: 889378:SPIAF_RS06835
uniprot id: H9UIV6
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

889378:SPIAF RS10105
gene id: 889378:SPIAF_RS10105
uniprot id: H9UKP5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

889378:SPIAF RS00410
gene id: 889378:SPIAF_RS00410
uniprot id: H9UF97
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

889378:SPIAF RS13995
gene id: 889378:SPIAF_RS13995
uniprot id: H9UMV2
names: Similarity
messages: Belongs to the band 7/mec-2 family.

889378:SPIAF RS13065
gene id: 889378:SPIAF_RS13065
uniprot id: H9UMB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

889378:SPIAF RS09380
gene id: 889378:SPIAF_RS09380
uniprot id: H9UKA6
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS07405
gene id: 889378:SPIAF_RS07405
uniprot id: H9UJ67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

889378:SPIAF RS05360
gene id: 889378:SPIAF_RS05360
uniprot id: H9UI24
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Monomer.

889378:SPIAF RS09625
gene id: 889378:SPIAF_RS09625
uniprot id: H9UKF2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

889378:SPIAF RS00515
gene id: 889378:SPIAF_RS00515
uniprot id: H9UFB7
names: Similarity
messages: Belongs to the disproportionating enzyme family.

889378:SPIAF RS09385
gene id: 889378:SPIAF_RS09385
uniprot id: H9UKA7
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

889378:SPIAF RS03255
gene id: 889378:SPIAF_RS03255
uniprot id: H9UGV4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

889378:SPIAF RS10290
gene id: 889378:SPIAF_RS10290
uniprot id: H9UKT2
names: Similarity
messages: Belongs to the heat shock protein 70 family.

889378:SPIAF RS09025
gene id: 889378:SPIAF_RS09025
uniprot id: H9UK38
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

889378:SPIAF RS12025
gene id: 889378:SPIAF_RS12025
uniprot id: H9ULR5
names: Similarity
messages: Belongs to the YicC/YloC family.

889378:SPIAF RS08060
gene id: 889378:SPIAF_RS08060
uniprot id: H9UJJ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

889378:SPIAF RS14695
gene id: 889378:SPIAF_RS14695
uniprot id: H9UI22
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

889378:SPIAF RS07025
gene id: 889378:SPIAF_RS07025
uniprot id: H9UIZ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

889378:SPIAF RS04065
gene id: 889378:SPIAF_RS04065
uniprot id: H9UHB4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

889378:SPIAF RS02885
gene id: 889378:SPIAF_RS02885
uniprot id: H9UGN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

889378:SPIAF RS02750
gene id: 889378:SPIAF_RS02750
uniprot id: H9UGK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

889378:SPIAF RS09020
gene id: 889378:SPIAF_RS09020
uniprot id: H9UK37
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

889378:SPIAF RS11625
gene id: 889378:SPIAF_RS11625
uniprot id: H9ULI5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

889378:SPIAF RS15000
gene id: 889378:SPIAF_RS15000
uniprot id: H9UKZ2
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS14200
gene id: 889378:SPIAF_RS14200
uniprot id: H9UMZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

889378:SPIAF RS11070
gene id: 889378:SPIAF_RS11070
uniprot id: H9UL78
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

889378:SPIAF RS05135
gene id: 889378:SPIAF_RS05135
uniprot id: H9UHX8
names: Similarity
messages: Belongs to the RutC family.

889378:SPIAF RS09860
gene id: 889378:SPIAF_RS09860
uniprot id: H9UKJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

889378:SPIAF RS07505
gene id: 889378:SPIAF_RS07505
uniprot id: H9UJ87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

889378:SPIAF RS13235
gene id: 889378:SPIAF_RS13235
uniprot id: H9UMF1
names: Subcellular Location Annotation
messages: Cytoplasm

889378:SPIAF RS00150
gene id: 889378:SPIAF_RS00150
uniprot id: H9UF45
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS08465
gene id: 889378:SPIAF_RS08465
uniprot id: H9UJS7
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

889378:SPIAF RS00335
gene id: 889378:SPIAF_RS00335
uniprot id: H9UF82
names: Subcellular Location Annotation
messages: Membrane

889378:SPIAF RS10645
gene id: 889378:SPIAF_RS10645
uniprot id: H9UKZ6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

889378:SPIAF RS01140
gene id: 889378:SPIAF_RS01140
uniprot id: H9UFP3
names: Similarity
messages: Belongs to the peptidase S16 family.

889378:SPIAF RS05890
gene id: 889378:SPIAF_RS05890
uniprot id: H9UIC5
names: Subcellular Location Annotation
messages: Membrane