8839:PIGW
gene id: 8839:PIGW
uniprot id: R0LTQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGW family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.

8839:NPY4R2
gene id: 8839:NPY4R2
uniprot id: R0JPY5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8839:SLC7A6
gene id: 8839:SLC7A6
uniprot id: R0JI70
names: Subcellular Location Annotation
messages: Membrane

8839:TSHR
gene id: 8839:TSHR
uniprot id: R0LII3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane
messages: Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.

8839:ASIP
gene id: 8839:ASIP
uniprot id: S4S2Z6
names: Subcellular Location Annotation
messages: Secreted

8839:GLDC
gene id: 8839:GLDC
uniprot id: Q9PUU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvP family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

8839:LOC101795347
gene id: 8839:LOC101795347
uniprot id: A0A8B9TDA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-microseminoprotein family.
messages: Secreted

8839:ALG2
gene id: 8839:ALG2
uniprot id: R0JF31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.
messages: Membrane

8839:EIF4A2
gene id: 8839:EIF4A2
uniprot id: A0A8B9TQG1
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

8839:CTTNBP2
gene id: 8839:CTTNBP2
uniprot id: A0A8B9TLS3
names: Subcellular Location Annotation
messages: cell cortex
messages: dendritic spine

8839:ROPN1L
gene id: 8839:ROPN1L
uniprot id: A0A8B9QR07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ropporin family.
messages: flagellum

8839:TMEM182
gene id: 8839:TMEM182
uniprot id: A0A8B9SF66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM182 family.
messages: Cell membrane
messages: Membrane

8839:ST3GAL6
gene id: 8839:ST3GAL6
uniprot id: R0M6H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8839:A4GNT
gene id: 8839:A4GNT
uniprot id: A0A8B9QRS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 32 family.
messages: Golgi apparatus membrane

8839:ALDH8A1
gene id: 8839:ALDH8A1
uniprot id: R0LUD3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

8839:HAO1
gene id: 8839:HAO1
uniprot id: A0A8B9T251
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

8839:CDX4
gene id: 8839:CDX4
uniprot id: A0A8B9QXL8
uniprot id: R0KF85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

8839:MC4R
gene id: 8839:MC4R
uniprot id: R0K294
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).

8839:MMP7
gene id: 8839:MMP7
uniprot id: A0A8B9QZI0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

8839:LOC101795634
gene id: 8839:LOC101795634
uniprot id: A0A8B9SGH2
names: Similarity
messages: Belongs to the protein kinase superfamily.

8839:LOC101805135
gene id: 8839:LOC101805135
uniprot id: A0A8B9SGR1
uniprot id: A0A8B9SHT1
names: Subcellular Location Annotation
messages: Membrane

8839:CHST8
gene id: 8839:CHST8
uniprot id: A0A8B9SW31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

8839:BLK
gene id: 8839:BLK
uniprot id: A0A8B9QV67
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8839:GSTT2B
gene id: 8839:GSTT2B
uniprot id: A0A8B9SM10
names: Similarity
messages: Belongs to the GST superfamily. Theta family.

8839:MYD88
gene id: 8839:MYD88
uniprot id: A0A0G2YMQ3
names: Function
names: Subcellular Location Annotation
messages: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
messages: Cytoplasm

8839:MSRB3
gene id: 8839:MSRB3
uniprot id: R0L7M1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.
messages: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.

8839:IDH1
gene id: 8839:IDH1
uniprot id: A0A8B9SQI5
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

8839:LOC101803775
gene id: 8839:LOC101803775
uniprot id: A0A8B9SQS1
names: Similarity
messages: Belongs to the serpin family.

8839:CTNNB1
gene id: 8839:CTNNB1
uniprot id: B5U453
names: Similarity
messages: Belongs to the beta-catenin family.

8839:SGMS2
gene id: 8839:SGMS2
uniprot id: R0LL24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

8839:LDB2
gene id: 8839:LDB2
uniprot id: R0K0T1
names: Similarity
messages: Belongs to the LDB family.

8839:KEG62 p11
gene id: 8839:KEG62_p11
uniprot id: A6ZJ01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

8839:SMC6
gene id: 8839:SMC6
uniprot id: A0A8B9QX51
names: Subcellular Location Annotation
messages: Chromosome

8839:GTF2H1
gene id: 8839:GTF2H1
uniprot id: R0L479
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB1 family.
messages: Nucleus

8839:PRIMPOL
gene id: 8839:PRIMPOL
uniprot id: R0J9J2
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

8839:PPM1K
gene id: 8839:PPM1K
uniprot id: R0KJ09
names: Similarity
messages: Belongs to the PP2C family.

8839:LOC101800713
gene id: 8839:LOC101800713
uniprot id: R0JDK1
names: Similarity
messages: Belongs to the globin family.

8839:HNF1A
gene id: 8839:HNF1A
uniprot id: R0L7K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HNF1 homeobox family.
messages: Nucleus

8839:TMEM144
gene id: 8839:TMEM144
uniprot id: R0K0M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM144 family.
messages: Membrane

8839:AGPAT3
gene id: 8839:AGPAT3
uniprot id: R0K9G9
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8839:RNH1
gene id: 8839:RNH1
uniprot id: R0LWZ6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Forms high-affinity heterodimers with RNASE1, ANG and RNASE2.
messages: Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play a role in redox homeostasis.

8839:LOC101789606
gene id: 8839:LOC101789606
uniprot id: Q27YS3
names: Caution
names: Function
names: Subunit
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.
messages: Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.

8839:FAM174B
gene id: 8839:FAM174B
uniprot id: R0KAY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM174 family.
messages: Membrane

8839:C1D
gene id: 8839:C1D
uniprot id: A0A8B9T8N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the C1D family.
messages: Cytoplasm
messages: Monomer and homodimer.
messages: Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA.
messages: nucleolus

8839:RPL15
gene id: 8839:RPL15
uniprot id: A0A8B9TMD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL15 family.
messages: Cytoplasm

8839:HSPB2
gene id: 8839:HSPB2
uniprot id: A0A8B9QZH2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

8839:TLR2
gene id: 8839:TLR2
uniprot id: M9NII1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
messages: Membrane

8839:LSM3
gene id: 8839:LSM3
uniprot id: A0A8B9T9S9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

8839:AZIN1
gene id: 8839:AZIN1
uniprot id: R0KD83
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

8839:PAX3
gene id: 8839:PAX3
uniprot id: I7EXJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

8839:SMIM18
gene id: 8839:SMIM18
uniprot id: R0KVR2
names: Subcellular Location Annotation
messages: Membrane

8839:FRMPD2
gene id: 8839:FRMPD2
uniprot id: A0A8B9TDT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

8839:LOC101797338
gene id: 8839:LOC101797338
uniprot id: R0LXX7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8839:KCNJ8
gene id: 8839:KCNJ8
uniprot id: R0LBG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8839:ATP11A
gene id: 8839:ATP11A
uniprot id: A0A8B9R6J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8839:ATP2A2
gene id: 8839:ATP2A2
uniprot id: R0LTI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Endoplasmic reticulum membrane
messages: Sarcoplasmic reticulum membrane

8839:RNASET2
gene id: 8839:RNASET2
uniprot id: R0JWF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase T2 family.
messages: Lysosome lumen

8839:CWC15
gene id: 8839:CWC15
uniprot id: R0M0S7
names: Similarity
messages: Belongs to the CWC15 family.

8839:FUT7
gene id: 8839:FUT7
uniprot id: R0K5B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

8839:STMN2
gene id: 8839:STMN2
uniprot id: A0A8B9SPQ2
names: Similarity
messages: Belongs to the stathmin family.

8839:LOC101803429
gene id: 8839:LOC101803429
uniprot id: A0A8B9ZAQ4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes.
messages: Homodimer; disulfide-linked.
messages: Membrane

8839:DDX58
gene id: 8839:DDX58
uniprot id: D3TI84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

8839:TRAF6
gene id: 8839:TRAF6
uniprot id: X5FNT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family. A subfamily.
messages: Lipid droplet
messages: Nucleus
messages: cell cortex

8839:PIWIL1
gene id: 8839:PIWIL1
uniprot id: A0A8B9T7Q0
names: Similarity
messages: Belongs to the argonaute family.

8839:LOC101802620
gene id: 8839:LOC101802620
uniprot id: A0A8B9TJS8
names: Subcellular Location Annotation
messages: Membrane

8839:CRHR2
gene id: 8839:CRHR2
uniprot id: R0M1I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Membrane

8839:MCM8
gene id: 8839:MCM8
uniprot id: R0L7Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

8839:TPM1
gene id: 8839:TPM1
uniprot id: A0A8B9TEN7
uniprot id: A0A8B9TER4
uniprot id: A0A8B9ZI02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

8839:GNB1
gene id: 8839:GNB1
uniprot id: A0A8B9ZJ82
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

8839:LOC101803608
gene id: 8839:LOC101803608
uniprot id: R0LP91
names: Subcellular Location Annotation
messages: Membrane

8839:LOC101800783
gene id: 8839:LOC101800783
uniprot id: V5J2K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MUSTANG family.
messages: Nucleus

8839:P2RY13
gene id: 8839:P2RY13
uniprot id: A0A8B9THN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8839:PIK3CA
gene id: 8839:PIK3CA
uniprot id: A0A8B9TNQ1
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8839:BTG4
gene id: 8839:BTG4
uniprot id: R0LF13
names: Similarity
messages: Belongs to the BTG family.

8839:LOC101792626
gene id: 8839:LOC101792626
uniprot id: Q2HZF4
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8839:MB
gene id: 8839:MB
uniprot id: R0K422
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

8839:OLAH
gene id: 8839:OLAH
uniprot id: A0A8B9TK78
uniprot id: P00633
names: Function
names: Similarity
messages: Belongs to the thioesterase family.
messages: In fatty acid biosynthesis chain termination and release of the free fatty acid product is achieved by hydrolysis of the thio ester by a thioesterase I, a component of the fatty acid synthetase complex. The chain length of the released fatty acid is usually C16. However, in the mammary glands of non-ruminant mammals, and in the uropygial gland of certain waterfowl there exists a second thioesterase which releases medium-chain length fatty acids (C8 to C2).

8839:IL2RG
gene id: 8839:IL2RG
uniprot id: F2W9Z7
names: Subcellular Location Annotation
messages: Membrane

8839:TNFAIP1
gene id: 8839:TNFAIP1
uniprot id: R0L3R1
names: Similarity
messages: Belongs to the BACURD family.

8839:TSSC4
gene id: 8839:TSSC4
uniprot id: R0L6J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TSSC4 family.
messages: Cytoplasm
messages: Nucleus

8839:GNGT2
gene id: 8839:GNGT2
uniprot id: R0JH78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8839:PRLR
gene id: 8839:PRLR
uniprot id: A5HDY5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Membrane
messages: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
messages: The box 1 motif is required for JAK interaction and/or activation.
messages: This is a receptor for the anterior pituitary hormone prolactin.

8839:GJB1
gene id: 8839:GJB1
uniprot id: R0K0K1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Beta-type (group I) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8839:LOC101802909
gene id: 8839:LOC101802909
uniprot id: Q4VSK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

8839:EHD3
gene id: 8839:EHD3
uniprot id: R0LDH3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

8839:BOK
gene id: 8839:BOK
uniprot id: R0KNK1
names: Similarity
messages: Belongs to the Bcl-2 family.

8839:EGF
gene id: 8839:EGF
uniprot id: R0JVC3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8839:NKAIN4
gene id: 8839:NKAIN4
uniprot id: A0A8B9SVG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

8839:FLI1
gene id: 8839:FLI1
uniprot id: A0A8B9TAP7
uniprot id: A0A8B9TBN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8839:MAB21L1
gene id: 8839:MAB21L1
uniprot id: R0LNV1
names: Similarity
messages: Belongs to the mab-21 family.

8839:PRL
gene id: 8839:PRL
uniprot id: Q75RW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

8839:CYLD
gene id: 8839:CYLD
uniprot id: R0LE64
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: centrosome
messages: cilium basal body
messages: perinuclear region
messages: spindle

8839:POLR2K
gene id: 8839:POLR2K
uniprot id: A0A8B9QXW2
names: Similarity
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.

8839:SLC1A1
gene id: 8839:SLC1A1
uniprot id: A0A088MHD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

8839:TF
gene id: 8839:TF
uniprot id: A0A8B9TQT4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferrin family.
messages: Monomer.
messages: Secreted

8839:LOC101802625
gene id: 8839:LOC101802625
uniprot id: A0A8B9SRR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tdpoz family.
messages: Nucleus speckle

8839:PFDN4
gene id: 8839:PFDN4
uniprot id: A0A8B9TNT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

8839:MPPED2
gene id: 8839:MPPED2
uniprot id: R0L1Q0
names: Similarity
messages: Belongs to the UPF0046 family.

8839:MGST2
gene id: 8839:MGST2
uniprot id: A0A8B9QUL6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8839:OAZ1
gene id: 8839:OAZ1
uniprot id: A0A8B9TH31
names: Similarity
messages: Belongs to the ODC antizyme family.

8839:LIPI
gene id: 8839:LIPI
uniprot id: A0A8B9QPL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

8839:HOXB9
gene id: 8839:HOXB9
uniprot id: A0A8B9QYJ6
uniprot id: R0L8K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8839:FAM83H
gene id: 8839:FAM83H
uniprot id: R0JHG4
names: Similarity
messages: Belongs to the FAM83 family.

8839:VPS26B
gene id: 8839:VPS26B
uniprot id: A0A8B9T247
names: Similarity
messages: Belongs to the VPS26 family.

8839:MYF6
gene id: 8839:MYF6
uniprot id: D5FZH6
names: Subcellular Location Annotation
messages: Nucleus

8839:NTMT1
gene id: 8839:NTMT1
uniprot id: A0A8B9STA9
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

8839:ARPC1A
gene id: 8839:ARPC1A
uniprot id: A0A8B9TDG1
names: Function
names: Similarity
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.

8839:LZIC
gene id: 8839:LZIC
uniprot id: A0A8B9TWP3
names: Similarity
messages: Belongs to the CTNNBIP1 family.

8839:ADI1
gene id: 8839:ADI1
uniprot id: A0A8B9Z7D8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.
messages: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

8839:SLC7A4
gene id: 8839:SLC7A4
uniprot id: A0A088MKA6
names: Subcellular Location Annotation
messages: Membrane

8839:NPTX2
gene id: 8839:NPTX2
uniprot id: R0LKI1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8839:LOC101791461
gene id: 8839:LOC101791461
uniprot id: R0JUP5
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

8839:LOC101797718
gene id: 8839:LOC101797718
uniprot id: Q5QFI1
names: Function
names: Similarity
messages: Belongs to the apovitellenin family.
messages: Protein component of the very low density lipoprotein (VLDL) of egg-laying females. Potent lipoprotein lipase inhibitor, preventing the loss of triglycerides from VLDL on their way from the liver to the growing oocytes.

8839:VGLL4
gene id: 8839:VGLL4
uniprot id: R0K604
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

8839:GFRA4
gene id: 8839:GFRA4
uniprot id: A0A8B9T090
names: Similarity
messages: Belongs to the GDNFR family.

8839:SSTR3
gene id: 8839:SSTR3
uniprot id: R0LU63
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8839:SPI1
gene id: 8839:SPI1
uniprot id: A0A8B9SQM9
uniprot id: A0A8B9SQR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8839:MMP23B
gene id: 8839:MMP23B
uniprot id: R0LPB3
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8839:LOC101799765
gene id: 8839:LOC101799765
uniprot id: L7R9Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

8839:IGF1
gene id: 8839:IGF1
uniprot id: A2IT63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

8839:AMOT
gene id: 8839:AMOT
uniprot id: A0A8B9T9B2
names: Similarity
messages: Belongs to the angiomotin family.

8839:UTS2
gene id: 8839:UTS2
uniprot id: A0A8B9T0V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urotensin-2 family.
messages: Secreted

8839:B3GNT9
gene id: 8839:B3GNT9
uniprot id: A0A8B9TQF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8839:CLDN16
gene id: 8839:CLDN16
uniprot id: A0A8B9T7V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8839:LOC101794808
gene id: 8839:LOC101794808
uniprot id: A0A8B9ZHJ8
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

8839:CCND1
gene id: 8839:CCND1
uniprot id: R0JP78
names: Similarity
messages: Belongs to the cyclin family.

8839:IL2RB
gene id: 8839:IL2RB
uniprot id: A0A8B9SUF6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Cell membrane
messages: Membrane
messages: Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit. Interacts with SHB upon interleukin stimulation.

8839:CYFIP1
gene id: 8839:CYFIP1
uniprot id: A0A8B9QUM5
names: Similarity
messages: Belongs to the CYFIP family.

8839:FGG
gene id: 8839:FGG
uniprot id: A0A8B9SHX5
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

8839:LOC101789562
gene id: 8839:LOC101789562
uniprot id: A0A8B9SWM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

8839:LOC101794184
gene id: 8839:LOC101794184
uniprot id: A0A8B9R3M6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8839:LOC101793492
gene id: 8839:LOC101793492
uniprot id: A0A8B9QTQ5
uniprot id: P33238
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
messages: By interferons.
messages: Cytoplasm
messages: Does not show activity against influenza virus or VSV.
messages: Nucleus

8839:DUSP26
gene id: 8839:DUSP26
uniprot id: A0A8B9SVG7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

8839:LOC101789807
gene id: 8839:LOC101789807
uniprot id: A0A8B9SPQ4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8839:COMT
gene id: 8839:COMT
uniprot id: R0JKM2
names: Cofactor
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Binds 1 Mg(2+) ion per subunit.

8839:LOC101792815
gene id: 8839:LOC101792815
uniprot id: A0A8B9SPZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: May play a role in lipid transport protein in Schwann cells. May bind cholesterol.
messages: Monomer.

8839:SLC41A3
gene id: 8839:SLC41A3
uniprot id: R0JJE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

8839:VAMP7
gene id: 8839:VAMP7
uniprot id: A0A8B9SI66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

8839:PLOD1
gene id: 8839:PLOD1
uniprot id: A0A8B9T868
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

8839:LOC101800628
gene id: 8839:LOC101800628
uniprot id: R0JY18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYBC1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8839:ZC3H12B
gene id: 8839:ZC3H12B
uniprot id: R0LIW5
names: Similarity
messages: Belongs to the ZC3H12 family.

8839:SEC23B
gene id: 8839:SEC23B
uniprot id: R0KAE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

8839:FAM20B
gene id: 8839:FAM20B
uniprot id: R0L7G4
names: Similarity
messages: Belongs to the FAM20 family.

8839:CRYAB
gene id: 8839:CRYAB
uniprot id: Q05557
names: Function
names: Similarity
names: Subunit
names: Tissue Specificity
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Heteromer composed of three CRYAA and one CRYAB subunits. Aggregates with homologous proteins, including the small heat shock protein HSPB1, to form large heteromeric complexes. Inter-subunit bridging via zinc ions enhances stability, which is crucial as there is no protein turn over in the lens (By similarity).
messages: Lens as well as other tissues.
messages: May contribute to the transparency and refractive index of the lens.

8839:EML4
gene id: 8839:EML4
uniprot id: A0A8B9SIS3
names: Similarity
messages: Belongs to the WD repeat EMAP family.

8839:TMEM45B
gene id: 8839:TMEM45B
uniprot id: R0JVR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

8839:SCPEP1
gene id: 8839:SCPEP1
uniprot id: A0A8B9SRQ2
names: Similarity
messages: Belongs to the peptidase S10 family.

8839:SGMS1
gene id: 8839:SGMS1
uniprot id: A0A8B9T045
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

8839:CX3CR1
gene id: 8839:CX3CR1
uniprot id: A0A8B9TLI6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8839:FOXJ2
gene id: 8839:FOXJ2
uniprot id: A0A8B9TEJ3
names: Subcellular Location Annotation
messages: Nucleus

8839:SNX5
gene id: 8839:SNX5
uniprot id: A0A8B9R1J2
names: Similarity
messages: Belongs to the sorting nexin family.

8839:POLR3F
gene id: 8839:POLR3F
uniprot id: R0M2C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
messages: Nucleus

8839:FGD3
gene id: 8839:FGD3
uniprot id: A0A8B9TVD5
names: Subcellular Location Annotation
messages: cytoskeleton

8839:EXOG
gene id: 8839:EXOG
uniprot id: A0A8B9QN82
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

8839:LOC101799083
gene id: 8839:LOC101799083
uniprot id: A0A8B9SFM4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8839:LOC101791068
gene id: 8839:LOC101791068
uniprot id: A0A8B9SGL2
names: Similarity
messages: Belongs to the cytochrome P450 family.

8839:MAPK13
gene id: 8839:MAPK13
uniprot id: R0JM53
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Interacts with MAPK8IP2.

8839:LOC101794704
gene id: 8839:LOC101794704
uniprot id: A0A8B9SW49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFI6/IFI27 family.
messages: Membrane

8839:GPATCH11
gene id: 8839:GPATCH11
uniprot id: A0A8B9SZQ9
names: Similarity
messages: Belongs to the GPATCH11 family.

8839:GJC1
gene id: 8839:GJC1
uniprot id: R0L8V9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Gamma-type subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8839:IL-2
gene id: 8839:IL-2
uniprot id: Q8JFF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-15/IL-21 family.
messages: Secreted

8839:EPS8
gene id: 8839:EPS8
uniprot id: A0A8B9TGA0
names: Similarity
messages: Belongs to the EPS8 family.

8839:C1GALT1
gene id: 8839:C1GALT1
uniprot id: R0KB96
names: Subcellular Location Annotation
messages: Membrane

8839:MED7
gene id: 8839:MED7
uniprot id: R0KLM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 7 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
messages: Component of the Mediator complex.
messages: Nucleus

8839:RAB27B
gene id: 8839:RAB27B
uniprot id: R0KAX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

8839:PARVB
gene id: 8839:PARVB
uniprot id: A0A8B9SMT9
names: Similarity
messages: Belongs to the parvin family.

8839:CER1
gene id: 8839:CER1
uniprot id: R0L8F5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8839:LOC101794469
gene id: 8839:LOC101794469
uniprot id: A0A8B9ZK04
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

8839:SLC1A7
gene id: 8839:SLC1A7
uniprot id: R0JFA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

8839:NDUFA8
gene id: 8839:NDUFA8
uniprot id: R0JBK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I NDUFA8 subunit family.
messages: Mitochondrion intermembrane space

8839:KEG62 p04
gene id: 8839:KEG62_p04
uniprot id: A6ZJ08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion membrane

8839:SULF1
gene id: 8839:SULF1
uniprot id: A0A8B9THE6
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

8839:ATP1B1
gene id: 8839:ATP1B1
uniprot id: Q6TG02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

8839:PDE7B
gene id: 8839:PDE7B
uniprot id: A0A8B9TB56
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8839:RIOX1
gene id: 8839:RIOX1
uniprot id: R0JQV0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROX family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Nucleus
messages: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.

8839:MAFB
gene id: 8839:MAFB
uniprot id: R0KAI9
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

8839:RIC8A
gene id: 8839:RIC8A
uniprot id: R0JAB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synembryn family.
messages: Cytoplasm
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
messages: Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.

8839:WNT8A
gene id: 8839:WNT8A
uniprot id: R0JCI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8839:LOC101790057
gene id: 8839:LOC101790057
uniprot id: R0KF96
names: Similarity
messages: Belongs to the cytochrome P450 family.

8839:LOC101794661
gene id: 8839:LOC101794661
uniprot id: A0A8B9R519
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8839:TFAP2D
gene id: 8839:TFAP2D
uniprot id: A0A8B9SH76
names: Similarity
messages: Belongs to the AP-2 family.

8839:ZNF532
gene id: 8839:ZNF532
uniprot id: R0LDY0
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

8839:DGLUCY
gene id: 8839:DGLUCY
uniprot id: A0A8B9SR88
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

8839:BDKRB2
gene id: 8839:BDKRB2
uniprot id: R0LJA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Forms a complex with PECAM1 and GNAQ. Interacts with PECAM1.
messages: Membrane
messages: Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.

8839:RFC1
gene id: 8839:RFC1
uniprot id: Q90238
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the activator 1 large subunit family.
messages: Nucleus

8839:TICAM1
gene id: 8839:TICAM1
uniprot id: A0A023PSZ2
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer. Found in a multi-helicase-TICAM1 complex at least composed of DHX36, DDX1, DDX21 and TICAM1.
messages: Involved in innate immunity against invading pathogens. Adapter used by TLR3, TLR4 (through TICAM2) and TLR5 to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively. Phosphorylation by TBK1 on the pLxIS motif leads to recruitment and subsequent activation of the transcription factor IRF3 to induce expression of type I interferon and exert a potent immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of pro-inflammatory cytokines.
messages: Mitochondrion
messages: The N-terminal region is essential for activation of the IFNB promoter activity.
messages: autophagosome
messages: cytosol

8839:GRIA4
gene id: 8839:GRIA4
uniprot id: A0A8B9QT37
uniprot id: R0K213
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8839:NIPAL2
gene id: 8839:NIPAL2
uniprot id: A0A8B9QZJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

8839:SCN3B
gene id: 8839:SCN3B
uniprot id: A0A8B9TQU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel auxiliary subunit SCN3B (TC 8.A.17) family.
messages: Membrane
messages: Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.

8839:RNF146
gene id: 8839:RNF146
uniprot id: R0M7I3
names: Domain
names: Function
names: PTM
names: Subcellular Location Annotation
messages: E3 ubiquitin-protein ligase that specifically binds poly-ADP-ribosylated proteins and mediates their ubiquitination and subsequent degradation.
messages: The WWE domain mediates non-covalent poly(ADP-ribose)-binding.
messages: Ubiquitinated; autoubiquitinated.
messages: cytosol

8839:MFN1
gene id: 8839:MFN1
uniprot id: A0A8B9TRP9
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

8839:PHB
gene id: 8839:PHB
uniprot id: A0A8B9QZA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

8839:RAB27A
gene id: 8839:RAB27A
uniprot id: R0M2P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

8839:LOC101803101
gene id: 8839:LOC101803101
uniprot id: R0LYJ5
names: Similarity
messages: In the C-terminal section; belongs to the GART family.
messages: In the N-terminal section; belongs to the GARS family.
messages: In the central section; belongs to the AIR synthase family.

8839:CD9
gene id: 8839:CD9
uniprot id: A0A8B9SFD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Cell membrane
messages: Membrane
messages: extracellular exosome

8839:CTLA4
gene id: 8839:CTLA4
uniprot id: D0V088
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
messages: Membrane

8839:ATP5F1E
gene id: 8839:ATP5F1E
uniprot id: R0LQK3
names: Function
names: Similarity
messages: Belongs to the eukaryotic ATPase epsilon family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

8839:ADIPOR2
gene id: 8839:ADIPOR2
uniprot id: Q2I0Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8839:RSPO3
gene id: 8839:RSPO3
uniprot id: A0A8B9Z827
names: Similarity
messages: Belongs to the R-spondin family.

8839:LOC101801660
gene id: 8839:LOC101801660
uniprot id: A0A8B9T190
names: Subcellular Location Annotation
messages: Membrane

8839:SLC24A1
gene id: 8839:SLC24A1
uniprot id: R0LV70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

8839:GDF2
gene id: 8839:GDF2
uniprot id: R0LGL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

8839:LOC101800520
gene id: 8839:LOC101800520
uniprot id: P04442
names: Developmental Stage
names: Function
names: Similarity
names: Subunit
names: Tissue Specificity
messages: Belongs to the globin family.
messages: Heterotetramer of two alpha-D chains and two beta chains.
messages: In birds, the alpha-D chain occurs in a minor hemoglobin component, called hemoglobin d, which is expressed in late embryonic and adult life.
messages: Involved in oxygen transport from the lung to the various peripheral tissues.
messages: Red blood cells.

8839:LOC101790335
gene id: 8839:LOC101790335
uniprot id: R0LMR1
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8839:EDNRA
gene id: 8839:EDNRA
uniprot id: R0LH46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with HDAC7 and KAT5.
messages: Membrane
messages: Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.

8839:GPNMB
gene id: 8839:GPNMB
uniprot id: A0A8B9QSZ3
names: Similarity
messages: Belongs to the PMEL/NMB family.

8839:UGP2
gene id: 8839:UGP2
uniprot id: A0A8B9T7Q7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDPGP type 1 family.
messages: Homooctamer.
messages: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.

8839:LOC101799731
gene id: 8839:LOC101799731
uniprot id: A0A8B9T1H7
names: Similarity
messages: Belongs to the peptidase C14A family.

8839:ANAPC10
gene id: 8839:ANAPC10
uniprot id: R0K4H8
names: Similarity
messages: Belongs to the APC10 family.

8839:LOC101805222
gene id: 8839:LOC101805222
uniprot id: A0A8B9QZH1
names: Similarity
messages: Belongs to the osteocalcin/matrix Gla protein family.

8839:MEF2C
gene id: 8839:MEF2C
uniprot id: I6VVT0
names: Subcellular Location Annotation
messages: Nucleus

8839:RAB32
gene id: 8839:RAB32
uniprot id: A0A8B9TBF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

8839:GPR155
gene id: 8839:GPR155
uniprot id: A0A8B9SKP0
names: Subcellular Location Annotation
messages: Membrane

8839:CD40LG
gene id: 8839:CD40LG
uniprot id: B5LX77
uniprot id: B5LX80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a ligand for integrins, specifically ITGA5:ITGB1 and ITGAV:ITGB3; both integrins and the CD40 receptor are required for activation of CD40-CD40LG signaling, which have cell-type dependent effects, such as B-cell activation, NF-kappa-B signaling and anti-apoptotic signaling.
messages: Belongs to the tumor necrosis factor family.
messages: Cell surface
messages: Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
messages: Homotrimer.

8839:ANXA13
gene id: 8839:ANXA13
uniprot id: A0A8B9TDN2
uniprot id: A0A8B9TE93
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

8839:LRRC8B
gene id: 8839:LRRC8B
uniprot id: R0L2M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

8839:GPR55
gene id: 8839:GPR55
uniprot id: A0A8B9TDE9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8839:KCNG1
gene id: 8839:KCNG1
uniprot id: A0A8B9TMF8
names: Subcellular Location Annotation
messages: Membrane

8839:TACR3
gene id: 8839:TACR3
uniprot id: A0A8B9ZL63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8839:TTI2
gene id: 8839:TTI2
uniprot id: R0KWG9
names: Similarity
messages: Belongs to the TTI2 family.

8839:KCND3
gene id: 8839:KCND3
uniprot id: R0K771
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

8839:SFR1
gene id: 8839:SFR1
uniprot id: R0M8M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFR1/MEI5 family.
messages: Nucleus

8839:RPL7
gene id: 8839:RPL7
uniprot id: A0A8B9SQN3
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

8839:NSMCE1
gene id: 8839:NSMCE1
uniprot id: A0A8B9QVV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE1 family.
messages: Component of the Smc5-Smc6 complex.
messages: Nucleus
messages: RING-type zinc finger-containing E3 ubiquitin ligase that assembles with melanoma antigen protein (MAGE) to catalyze the direct transfer of ubiquitin from E2 ubiquitin-conjugating enzyme to a specific substrate. Involved in maintenance of genome integrity, DNA damage response and DNA repair.
messages: telomere

8839:ELAVL4
gene id: 8839:ELAVL4
uniprot id: A0A8B9ZKL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM elav family.
messages: Cytoplasm
messages: Perikaryon
messages: axon
messages: dendrite
messages: growth cone

8839:LOC101797806
gene id: 8839:LOC101797806
uniprot id: R0L488
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

8839:RTN1
gene id: 8839:RTN1
uniprot id: A0A8B9SNC6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8839:DLX1
gene id: 8839:DLX1
uniprot id: A0A8B9SUL8
names: Subcellular Location Annotation
messages: Nucleus

8839:MC2R
gene id: 8839:MC2R
uniprot id: R0LPF7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with MRAP; increasing ligand-sensitivity and generation of cAMP. Interacts with MRAP2; competing with MRAP for binding to MC2R and impairing the binding of corticotropin (ACTH).
messages: Membrane

8839:MAPKAPK3
gene id: 8839:MAPKAPK3
uniprot id: R0JHI4
names: Similarity
messages: Belongs to the protein kinase superfamily.

8839:SOAT1
gene id: 8839:SOAT1
uniprot id: A0A8B9TQK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

8839:LOC101793645
gene id: 8839:LOC101793645
uniprot id: R0LUA1
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

8839:RAB9B
gene id: 8839:RAB9B
uniprot id: R0L267
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: phagosome membrane

8839:EREG
gene id: 8839:EREG
uniprot id: A0A8B9T3C9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8839:TIMP3
gene id: 8839:TIMP3
uniprot id: R0KBG0
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

8839:CALHM2
gene id: 8839:CALHM2
uniprot id: R0L4V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

8839:MPPED1
gene id: 8839:MPPED1
uniprot id: R0JBB5
names: Similarity
messages: Belongs to the UPF0046 family.

8839:ASPN
gene id: 8839:ASPN
uniprot id: A0A8B9TVJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: extracellular matrix

8839:LANCL1
gene id: 8839:LANCL1
uniprot id: R0JR71
names: Similarity
messages: Belongs to the LanC-like protein family.

8839:LOC101804810
gene id: 8839:LOC101804810
uniprot id: A0A8B9ZH41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8839:DLC1
gene id: 8839:DLC1
uniprot id: A0A8B9T536
names: Subcellular Location Annotation
messages: Cytoplasm

8839:GLP1R
gene id: 8839:GLP1R
uniprot id: A0A8B9SQS9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8839:EHF
gene id: 8839:EHF
uniprot id: R0LNP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8839:BFSP1
gene id: 8839:BFSP1
uniprot id: A0A8B9ZFN2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: cell cortex
messages: cytoskeleton

8839:GPR34
gene id: 8839:GPR34
uniprot id: A0A8B9T978
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Orphan receptor.

8839:LOC101792365
gene id: 8839:LOC101792365
uniprot id: A0A8B9SRL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

8839:MALL
gene id: 8839:MALL
uniprot id: A0A8B9ZGS2
names: Subcellular Location Annotation
messages: Membrane

8839:FUT8
gene id: 8839:FUT8
uniprot id: A0A8B9SQH4
uniprot id: R0L7J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 23 family.
messages: Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.
messages: Golgi stack membrane
messages: Membrane

8839:IFITM5
gene id: 8839:IFITM5
uniprot id: W8W3S8
names: Similarity
messages: Belongs to the CD225/Dispanin family.

8839:WNT11
gene id: 8839:WNT11
uniprot id: A0A8B9SG73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8839:B3GALT5
gene id: 8839:B3GALT5
uniprot id: A0A8B9ZD01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8839:ORMDL1
gene id: 8839:ORMDL1
uniprot id: R0KBM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Membrane

8839:PPP1R13B
gene id: 8839:PPP1R13B
uniprot id: A0A8B9TPN8
names: Subcellular Location Annotation
messages: Nucleus

8839:WNT7A
gene id: 8839:WNT7A
uniprot id: R0LCX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8839:LOC101803950
gene id: 8839:LOC101803950
uniprot id: R0K8E4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8839:ABCG1
gene id: 8839:ABCG1
uniprot id: A0A8B9QRZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

8839:CDH5
gene id: 8839:CDH5
uniprot id: R0L614
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

8839:GPER1
gene id: 8839:GPER1
uniprot id: A0A8B9R2A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8839:ZDHHC3
gene id: 8839:ZDHHC3
uniprot id: A0A8B9SMZ1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8839:IFIH1
gene id: 8839:IFIH1
uniprot id: A0A023NCT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

8839:PPP1R1C
gene id: 8839:PPP1R1C
uniprot id: A0A8B9SRA9
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 1 family.

8839:LOC101794114
gene id: 8839:LOC101794114
uniprot id: A0A8B9TQX8
names: Similarity
messages: Belongs to the folate receptor family.

8839:LOC101797666
gene id: 8839:LOC101797666
uniprot id: R0JJ64
names: Similarity
messages: Belongs to the cytochrome P450 family.

8839:ID2
gene id: 8839:ID2
uniprot id: R0LU90
names: Subcellular Location Annotation
messages: Nucleus

8839:PDGFRA
gene id: 8839:PDGFRA
uniprot id: A0A8B9T5H7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Interacts with homodimeric PDGFA, PDGFB and PDGFC, and with heterodimers formed by PDGFA and PDGFB. Monomer in the absence of bound ligand.
messages: Membrane
messages: Present in an inactive conformation in the absence of bound ligand. Binding of PDGFA and/or PDGFB leads to dimerization and activation by autophosphorylation on tyrosine residues.
messages: Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.

8839:HMOX1
gene id: 8839:HMOX1
uniprot id: A0A172QNS1
names: Similarity
messages: Belongs to the heme oxygenase family.

8839:SYS1
gene id: 8839:SYS1
uniprot id: R0L9I0
names: Subcellular Location Annotation
messages: Membrane

8839:CPD
gene id: 8839:CPD
uniprot id: Q90240
names: Cofactor
names: Domain
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Belongs to the peptidase M14 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Binds to pre-S, hepatitis B virus large envelope protein, via the carboxypeptidase-like domain.
messages: Cell membrane
messages: Expressed in liver, lung, kidney, heart, stomach, pancreas, spleen, gall bladder and intestine, but not in skeletal muscle.
messages: The N-terminus is blocked.
messages: There are 3 carboxypeptidase domains. Only the first two domains have any catalytic activity. The first domain preferentially cleaves C-terminal Arg residues, whereas the second preferentially cleaves C-terminal Lys residues. The third domain binds to pre-S, hepatitis B virus large envelope protein.

8839:LOC101803851
gene id: 8839:LOC101803851
uniprot id: A0A8B9TSP5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8839:IP6K1
gene id: 8839:IP6K1
uniprot id: A0A8B9TY83
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

8839:LOC101800358
gene id: 8839:LOC101800358
uniprot id: A0A8B9ZF72
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

8839:HINT1
gene id: 8839:HINT1
uniprot id: Q9I839
names: Similarity
messages: Belongs to the HINT family.

8839:NTS
gene id: 8839:NTS
uniprot id: A0A8B9R0V9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurotensin family.
messages: Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.
messages: Secreted
messages: Vesicle
messages: secretory vesicle

8839:LOC101804095
gene id: 8839:LOC101804095
uniprot id: A0A8B9ZCR5
names: Similarity
messages: Belongs to the serpin family.

8839:EMP2
gene id: 8839:EMP2
uniprot id: A0A8B9T340
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Membrane raft
messages: Nucleus
messages: perinuclear region

8839:ACTB
gene id: 8839:ACTB
uniprot id: A6ZIB9
names: Similarity
messages: Belongs to the actin family.

8839:RNF4
gene id: 8839:RNF4
uniprot id: A0A8B9T1V0
names: Subcellular Location Annotation
messages: Nucleus

8839:ATP6V1G3
gene id: 8839:ATP6V1G3
uniprot id: A0A8B9SLE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

8839:NR2F2
gene id: 8839:NR2F2
uniprot id: A0A8B9TGA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8839:NR0B2
gene id: 8839:NR0B2
uniprot id: A0A8B9SK79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus

8839:SOST
gene id: 8839:SOST
uniprot id: A0A8B9SYP6
names: Caution
names: Similarity
messages: Belongs to the sclerostin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8839:LOC101795199
gene id: 8839:LOC101795199
uniprot id: A0A089RQF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

8839:ALB
gene id: 8839:ALB
uniprot id: I6U3L8
names: Subcellular Location Annotation
messages: Secreted

8839:GLRA2
gene id: 8839:GLRA2
uniprot id: A0A8B9TQD0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

8839:LOC101802261
gene id: 8839:LOC101802261
uniprot id: R0L6P5
names: Similarity
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.

8839:PLA2G4A
gene id: 8839:PLA2G4A
uniprot id: A0A8B9SJF3
names: Domain
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.

8839:FABP2
gene id: 8839:FABP2
uniprot id: G1FHQ9
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8839:SULT6B1
gene id: 8839:SULT6B1
uniprot id: A0A8B9T4Z3
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8839:FOXO1
gene id: 8839:FOXO1
uniprot id: R0LSX8
names: Subcellular Location Annotation
messages: Nucleus

8839:BRS3
gene id: 8839:BRS3
uniprot id: R0JM57
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with C6orf89.
messages: Membrane

8839:KEG62 p09
gene id: 8839:KEG62_p09
uniprot id: A6ZJ03
uniprot id: P50655
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase protein 8 family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane (By similarity).
messages: Mitochondrion membrane

8839:ACE2
gene id: 8839:ACE2
uniprot id: R0LHX5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M2 family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Secreted
messages: cilium

8839:PKIB
gene id: 8839:PKIB
uniprot id: R0JZ82
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

8839:SPOCK1
gene id: 8839:SPOCK1
uniprot id: A0A8B9TTZ1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8839:TLR4
gene id: 8839:TLR4
uniprot id: G8FUB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8839:CSGALNACT1
gene id: 8839:CSGALNACT1
uniprot id: R0L7C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

8839:HCRTR2
gene id: 8839:HCRTR2
uniprot id: R0KET9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8839:LRP8
gene id: 8839:LRP8
uniprot id: I6VXR2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8839:DCP1B
gene id: 8839:DCP1B
uniprot id: R0KCP9
names: Similarity
messages: Belongs to the DCP1 family.

8839:LOC101792171
gene id: 8839:LOC101792171
uniprot id: A0A8B9T535
names: Subcellular Location Annotation
messages: Membrane

8839:KEG62 p13
gene id: 8839:KEG62_p13
uniprot id: A6ZIZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 1 family.
messages: Membrane
messages: Mitochondrion inner membrane

8839:LOC101803171
gene id: 8839:LOC101803171
uniprot id: R0LKG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Cell membrane
messages: Membrane

8839:TEF
gene id: 8839:TEF
uniprot id: A0A8B9QYT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

8839:FBLN5
gene id: 8839:FBLN5
uniprot id: A0A8B9SRD4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8839:GEM
gene id: 8839:GEM
uniprot id: R0KL90
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

8839:LOC101794349
gene id: 8839:LOC101794349
uniprot id: A0A8B9QYW3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

8839:UBE3A
gene id: 8839:UBE3A
uniprot id: A0A8B9QVL0
uniprot id: A0A8B9R429
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
messages: Nucleus

8839:GPX8
gene id: 8839:GPX8
uniprot id: R0L669
names: Similarity
messages: Belongs to the glutathione peroxidase family.

8839:SLC15A1
gene id: 8839:SLC15A1
uniprot id: A0A088MTY4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Interacts (via extracellular domain region) with trypsin.
messages: Membrane

8839:SLC34A2
gene id: 8839:SLC34A2
uniprot id: A0A8B9TMR3
uniprot id: R0L7I2
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Membrane

8839:LOC101791108
gene id: 8839:LOC101791108
uniprot id: R0L2K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRPH2/ROM1 family.
messages: Membrane

8839:NTNG1
gene id: 8839:NTNG1
uniprot id: R0L0R7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8839:TXK
gene id: 8839:TXK
uniprot id: A0A8B9ZHS1
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8839:LOC101800121
gene id: 8839:LOC101800121
uniprot id: A0A8B9TVX5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-5/CLCN5 subfamily.
messages: Cell membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Interacts with NEDD4 and NEDD4L.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8839:GPR6
gene id: 8839:GPR6
uniprot id: A0A8E7PED9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8839:MYOD1
gene id: 8839:MYOD1
uniprot id: C3U0I1
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

8839:TAC1
gene id: 8839:TAC1
uniprot id: A0A8B9R0S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted
messages: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.

8839:RECQL
gene id: 8839:RECQL
uniprot id: A0A8B9QPF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecQ subfamily.
messages: Nucleus

8839:HOXD12
gene id: 8839:HOXD12
uniprot id: A0A8B9SJV5
uniprot id: R0LVC1
names: Subcellular Location Annotation
messages: Nucleus

8839:FAM118B
gene id: 8839:FAM118B
uniprot id: A0A8B9TAN4
names: Similarity
messages: Belongs to the FAM118 family.

8839:ZFX
gene id: 8839:ZFX
uniprot id: A0A8B9T2X2
names: Subcellular Location Annotation
messages: Nucleus

8839:GRIN2B
gene id: 8839:GRIN2B
uniprot id: R0M229
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

8839:FZD4
gene id: 8839:FZD4
uniprot id: R0JEY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Membrane

8839:LOC101795933
gene id: 8839:LOC101795933
uniprot id: A0A3G2VSX8
names: Similarity
messages: Belongs to the NLRP family.

8839:SFRP2
gene id: 8839:SFRP2
uniprot id: C7AFG0
uniprot id: R0L3X7
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8839:ST6GAL2
gene id: 8839:ST6GAL2
uniprot id: A0A8B9QRS5
uniprot id: R0M1I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8839:GH1
gene id: 8839:GH1
uniprot id: P11228
uniprot id: Q549W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Growth hormone plays an important role in growth control.
messages: Secreted

8839:MAFG
gene id: 8839:MAFG
uniprot id: R0LZB5
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

8839:MBOAT4
gene id: 8839:MBOAT4
uniprot id: A0A8B9SGV1
names: Subcellular Location Annotation
messages: Membrane

8839:MED9
gene id: 8839:MED9
uniprot id: R0KC06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 9 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8839:RAB9A
gene id: 8839:RAB9A
uniprot id: R0LG13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: phagosome membrane

8839:LOC101795398
gene id: 8839:LOC101795398
uniprot id: L7X0M5
names: Similarity
messages: Belongs to the LECT2/MIM-1 family.

8839:ENTPD1
gene id: 8839:ENTPD1
uniprot id: A0A8B9TQS8
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

8839:TECR
gene id: 8839:TECR
uniprot id: A0A8B9T559
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane

8839:STK38L
gene id: 8839:STK38L
uniprot id: A0A8B9SPQ8
names: Similarity
messages: Belongs to the protein kinase superfamily.

8839:KCNMB1
gene id: 8839:KCNMB1
uniprot id: R0LAZ7
names: Subcellular Location Annotation
messages: Membrane

8839:NPBWR2
gene id: 8839:NPBWR2
uniprot id: A0A8B9T8H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8839:CNOT6
gene id: 8839:CNOT6
uniprot id: R0L9D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

8839:SPP2
gene id: 8839:SPP2
uniprot id: A0A386GZQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPP2 family.
messages: Could coordinate an aspect of bone turnover.
messages: Secreted

8839:GIMD1
gene id: 8839:GIMD1
uniprot id: R0L6C2
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8839:LOC101798542
gene id: 8839:LOC101798542
uniprot id: R0LY36
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8839:LOC101802825
gene id: 8839:LOC101802825
uniprot id: A0A8B9SSG6
names: Similarity
messages: Belongs to the intercrine gamma family.

8839:RPS6KA3
gene id: 8839:RPS6KA3
uniprot id: A0A8B9T3Q9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

8839:CHRNA9
gene id: 8839:CHRNA9
uniprot id: A0A8B9TKP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8839:HAPLN1
gene id: 8839:HAPLN1
uniprot id: R0K8V6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8839:PLIN1
gene id: 8839:PLIN1
uniprot id: F6KFT3
names: Similarity
messages: Belongs to the perilipin family.

8839:GGT1
gene id: 8839:GGT1
uniprot id: A0A8B9R6I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

8839:LOC101800257
gene id: 8839:LOC101800257
uniprot id: A0A8B9QQA0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted

8839:KEG62 p05
gene id: 8839:KEG62_p05
uniprot id: A6ZJ07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4L family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
messages: Membrane
messages: Mitochondrion inner membrane

8839:GALNT18
gene id: 8839:GALNT18
uniprot id: A0A8B9SUI9
uniprot id: A0A8B9SUL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8839:B3GNT2
gene id: 8839:B3GNT2
uniprot id: R0JVT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8839:GJC2
gene id: 8839:GJC2
uniprot id: R0JLL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8839:S1PR4
gene id: 8839:S1PR4
uniprot id: A0A8B9ST54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8839:DNAAF6
gene id: 8839:DNAAF6
uniprot id: A0A8B9ZKV3
names: Similarity
messages: Belongs to the PIH1 family.

8839:BRINP3
gene id: 8839:BRINP3
uniprot id: R0M2X6
names: Similarity
messages: Belongs to the BRINP family.

8839:ENO1
gene id: 8839:ENO1
uniprot id: P19140
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Binds two Mg(2+) per subunit. Required for catalysis and for stabilizing the dimer.
messages: Both an enzyme and a lens structural protein.
messages: Cytoplasm
messages: Homodimer.

8839:PKIG
gene id: 8839:PKIG
uniprot id: A0A8B9T269
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

8839:SULF2
gene id: 8839:SULF2
uniprot id: A0A8B9SZZ0
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

8839:CD2
gene id: 8839:CD2
uniprot id: A0A8B9TJC2
uniprot id: A0A8B9TLB4
names: Subcellular Location Annotation
messages: Membrane

8839:RHBDF1
gene id: 8839:RHBDF1
uniprot id: A0A8B9TX08
uniprot id: R0JDL0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

8839:UTS2B
gene id: 8839:UTS2B
uniprot id: A0A8B9T8J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urotensin-2 family.
messages: Secreted

8839:MSTN
gene id: 8839:MSTN
uniprot id: R0KAD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts specifically as a negative regulator of skeletal muscle growth.
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Secreted

8839:CFLAR
gene id: 8839:CFLAR
uniprot id: A0A8B9T0L2
names: Similarity
messages: Belongs to the peptidase C14A family.

8839:MRRF
gene id: 8839:MRRF
uniprot id: A0A8B9TK29
names: Function
names: Similarity
messages: Belongs to the RRF family.
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

8839:LOC101797566
gene id: 8839:LOC101797566
uniprot id: R0KFP7
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

8839:HOXA11
gene id: 8839:HOXA11
uniprot id: A0A8B9QTJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8839:SLC7A1
gene id: 8839:SLC7A1
uniprot id: A0A088MGN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

8839:RCAN1
gene id: 8839:RCAN1
uniprot id: R0K6W3
names: Similarity
messages: Belongs to the RCAN family.

8839:SKI
gene id: 8839:SKI
uniprot id: R0M4F9
names: Similarity
messages: Belongs to the SKI family.

8839:CHRM3
gene id: 8839:CHRM3
uniprot id: A0A8B9SMB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

8839:CLDN18
gene id: 8839:CLDN18
uniprot id: R0L7C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

8839:B3GNT5
gene id: 8839:B3GNT5
uniprot id: A0A8B9TQ03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8839:LOC101793815
gene id: 8839:LOC101793815
uniprot id: A0A8B9R2I9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8839:FUT9
gene id: 8839:FUT9
uniprot id: R0JS59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

8839:ACTN2
gene id: 8839:ACTN2
uniprot id: R0JMH7
names: Similarity
messages: Belongs to the alpha-actinin family.

8839:POU1F1
gene id: 8839:POU1F1
uniprot id: A0A8X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

8839:LOC101804267
gene id: 8839:LOC101804267
uniprot id: A0A8B9R7M0
names: Similarity
messages: Belongs to the cytochrome P450 family.

8839:DDC
gene id: 8839:DDC
uniprot id: R0LFC9
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

8839:F13A1
gene id: 8839:F13A1
uniprot id: R0KCX2
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

8839:NLGN1
gene id: 8839:NLGN1
uniprot id: A0A8B9TNM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

8839:LOC101801612
gene id: 8839:LOC101801612
uniprot id: A0A8B9R5V6
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

8839:LPIN1
gene id: 8839:LPIN1
uniprot id: A0A8B9SG69
names: Similarity
messages: Belongs to the lipin family.

8839:STIM2
gene id: 8839:STIM2
uniprot id: A0A8B9TK12
names: Subcellular Location Annotation
messages: Membrane

8839:SLCO5A1
gene id: 8839:SLCO5A1
uniprot id: R0L7E6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted

8839:LOC101795602
gene id: 8839:LOC101795602
uniprot id: A0A8B9TK09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

8839:TMEM229B
gene id: 8839:TMEM229B
uniprot id: R0JPG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM229 family.
messages: Membrane

8839:LIPA
gene id: 8839:LIPA
uniprot id: A0A8B9ZHY0
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

8839:NOS2
gene id: 8839:NOS2
uniprot id: F0UYP7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NOS family.
messages: Binds 1 FAD.
messages: Binds 1 FMN.
messages: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.

8839:PPP2R2B
gene id: 8839:PPP2R2B
uniprot id: A0A8B9TB29
uniprot id: A0A8B9ZHU3
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

8839:LOC101794702
gene id: 8839:LOC101794702
uniprot id: A0A8B9TUS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 2H phosphoesterase superfamily. CNPase family.
messages: Exists as monomers and homodimers.
messages: May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin.
messages: Melanosome
messages: Membrane

8839:LOC101801566
gene id: 8839:LOC101801566
uniprot id: A0A8B9T9A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

8839:GFRA1
gene id: 8839:GFRA1
uniprot id: A0A8B9SPA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDNFR family.
messages: Cell membrane
messages: Membrane

8839:VDAC3
gene id: 8839:VDAC3
uniprot id: A0A8B9T595
names: Similarity
messages: Belongs to the eukaryotic mitochondrial porin family.

8839:WNT3
gene id: 8839:WNT3
uniprot id: A0A8B9QYQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8839:CDR2L
gene id: 8839:CDR2L
uniprot id: A0A8B9SVN3
names: Similarity
messages: Belongs to the CDR2 family.

8839:ST3GAL1
gene id: 8839:ST3GAL1
uniprot id: R0M5M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8839:MB21D2
gene id: 8839:MB21D2
uniprot id: R0JBC9
names: Similarity
messages: Belongs to the mab-21 family.

8839:MEOX1
gene id: 8839:MEOX1
uniprot id: A0A8B9SY94
names: Subcellular Location Annotation
messages: Nucleus

8839:HOXB8
gene id: 8839:HOXB8
uniprot id: A0A8B9QYE4
uniprot id: R0L5D3
names: Subcellular Location Annotation
messages: Nucleus

8839:EXOC1
gene id: 8839:EXOC1
uniprot id: A0A8B9T5E8
names: Similarity
messages: Belongs to the SEC3 family.

8839:DUSP29
gene id: 8839:DUSP29
uniprot id: A0A8B9TGB6
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

8839:P2RX7
gene id: 8839:P2RX7
uniprot id: A0A8B9T9J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P2X receptor family.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

8839:CCR6
gene id: 8839:CCR6
uniprot id: A0A8B9QT21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

8839:PRPF38B
gene id: 8839:PRPF38B
uniprot id: R0L434
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP38 family.
messages: May be required for pre-mRNA splicing.
messages: Nucleus

8839:HEATR5B
gene id: 8839:HEATR5B
uniprot id: R0JPU4
names: Similarity
messages: Belongs to the HEATR5 family.

8839:TLL1
gene id: 8839:TLL1
uniprot id: A0A8B9SGP9
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8839:SLC7A9
gene id: 8839:SLC7A9
uniprot id: A0A088MKB1
names: Subcellular Location Annotation
messages: Membrane

8839:LOC106018249
gene id: 8839:LOC106018249
uniprot id: A0A0C4WTG8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8839:RFTN2
gene id: 8839:RFTN2
uniprot id: R0LDK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the raftlin family.
messages: Cell membrane
messages: Membrane

8839:PRPH2
gene id: 8839:PRPH2
uniprot id: R0K469
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRPH2/ROM1 family.
messages: Membrane

8839:SYN3
gene id: 8839:SYN3
uniprot id: A0A8B9TT72
names: Similarity
messages: Belongs to the synapsin family.

8839:LOC101802686
gene id: 8839:LOC101802686
uniprot id: A0A8B9TKX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIG1 family.
messages: Membrane

8839:TNFSF13B
gene id: 8839:TNFSF13B
uniprot id: Q0QCV8
names: Similarity
messages: Belongs to the tumor necrosis factor family.

8839:ADSL
gene id: 8839:ADSL
uniprot id: K9LGB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

8839:LOC101792898
gene id: 8839:LOC101792898
uniprot id: A0A8B9SZL1
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8839:HOXB3
gene id: 8839:HOXB3
uniprot id: R0L5D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

8839:CCNI
gene id: 8839:CCNI
uniprot id: A0A8B9SJ09
names: Similarity
messages: Belongs to the cyclin family.

8839:MRPL20
gene id: 8839:MRPL20
uniprot id: R0M552
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.

8839:NSFL1C
gene id: 8839:NSFL1C
uniprot id: R0KV36
names: Subcellular Location Annotation
messages: Golgi stack

8839:IL10RB
gene id: 8839:IL10RB
uniprot id: L7X844
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tissue factor family.
messages: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
messages: Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII.

8839:GJA1
gene id: 8839:GJA1
uniprot id: R0LB91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8839:HOXB6
gene id: 8839:HOXB6
uniprot id: A0A8B9QYM4
uniprot id: R0JHZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

8839:LOC101797113
gene id: 8839:LOC101797113
uniprot id: R0LQE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

8839:CDPF1
gene id: 8839:CDPF1
uniprot id: R0LRD9
names: Similarity
messages: Belongs to the CDPF1 family.

8839:PPARGC1A
gene id: 8839:PPARGC1A
uniprot id: A0A8B9TLU8
names: Subcellular Location Annotation
messages: PML body

8839:SLC24A5
gene id: 8839:SLC24A5
uniprot id: S4SXD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

8839:TLR-15
gene id: 8839:TLR-15
uniprot id: J7FJ07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8839:ADORA2A
gene id: 8839:ADORA2A
uniprot id: A0A8B9SHX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

8839:KEG62 p07
gene id: 8839:KEG62_p07
uniprot id: Q0ZA04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane

8839:A1CF
gene id: 8839:A1CF
uniprot id: R0JZB9
names: Subcellular Location Annotation
messages: Cytoplasm

8839:LOC101799801
gene id: 8839:LOC101799801
uniprot id: A0A8B9QL37
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted

8839:CAPN6
gene id: 8839:CAPN6
uniprot id: R0LVR4
names: Similarity
messages: Belongs to the peptidase C2 family.

8839:DLGAP1
gene id: 8839:DLGAP1
uniprot id: R0LSN8
names: Similarity
messages: Belongs to the SAPAP family.

8839:SLC20A2
gene id: 8839:SLC20A2
uniprot id: R0JJB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter.

8839:LOC101793992
gene id: 8839:LOC101793992
uniprot id: R0LM15
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8839:SERPINA10
gene id: 8839:SERPINA10
uniprot id: A0A8B9SQL8
names: Similarity
messages: Belongs to the serpin family.

8839:IFITM2
gene id: 8839:IFITM2
uniprot id: A0A0C4K5J8
names: Similarity
messages: Belongs to the CD225/Dispanin family.

8839:PCK1
gene id: 8839:PCK1
uniprot id: R0LQQ0
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.

8839:FSHB
gene id: 8839:FSHB
uniprot id: Q0ZR38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

8839:PCBD1
gene id: 8839:PCBD1
uniprot id: A0A8B9SN49
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

8839:INO80
gene id: 8839:INO80
uniprot id: A0A8B9QS26
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Component of the INO80 chromatin-remodeling complex.
messages: Nucleus
messages: The DBINO region is involved in binding to DNA.

8839:KCNJ3
gene id: 8839:KCNJ3
uniprot id: R0KE04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
messages: Membrane
messages: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

8839:FGF7
gene id: 8839:FGF7
uniprot id: R0LIH0
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8839:LOC101801984
gene id: 8839:LOC101801984
uniprot id: R0JS98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted

8839:GDAP2
gene id: 8839:GDAP2
uniprot id: A0A8B9Z8I7
names: Similarity
messages: Belongs to the GDAP2 family.

8839:SMAD5
gene id: 8839:SMAD5
uniprot id: A0A8B9TUN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

8839:RPF2
gene id: 8839:RPF2
uniprot id: A0A8B9SUP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPF2 family.
messages: nucleolus

8839:SEMA3E
gene id: 8839:SEMA3E
uniprot id: R0LRL3
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8839:TM4SF18
gene id: 8839:TM4SF18
uniprot id: A0A8B9R087
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

8839:ANTXRL
gene id: 8839:ANTXRL
uniprot id: A0A8B9TDV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

8839:TNFAIP6
gene id: 8839:TNFAIP6
uniprot id: R0M6H9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8839:FZD10
gene id: 8839:FZD10
uniprot id: A0A8B9T6D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

8839:LOC101805249
gene id: 8839:LOC101805249
uniprot id: A0A0C5B1C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8839:PTAFR
gene id: 8839:PTAFR
uniprot id: A0A8B9TFD8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with ARRB1.
messages: Membrane

8839:MIGA2
gene id: 8839:MIGA2
uniprot id: R0LVY4
names: Similarity
messages: Belongs to the mitoguardin family.

8839:HAL
gene id: 8839:HAL
uniprot id: R0LGR4
names: Similarity
messages: Belongs to the PAL/histidase family.

8839:HAUS3
gene id: 8839:HAUS3
uniprot id: A0A8B9T2B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS3 family.
messages: spindle

8839:CCDC181
gene id: 8839:CCDC181
uniprot id: R0JHX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC181 family.
messages: Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids.
messages: cytoskeleton

8839:SMPX
gene id: 8839:SMPX
uniprot id: A0A8B9ZG25
names: Function
names: Similarity
messages: Belongs to the SMPX family.
messages: Plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair.

8839:LOC101791705
gene id: 8839:LOC101791705
uniprot id: K7WPA4
names: Subcellular Location Annotation
messages: Nucleus

8839:YPEL5
gene id: 8839:YPEL5
uniprot id: R0JQY4
names: Similarity
messages: Belongs to the yippee family.

8839:SPSB1
gene id: 8839:SPSB1
uniprot id: R0LRP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

8839:FASN
gene id: 8839:FASN
uniprot id: A0A0D3LZ43
names: Function
messages: Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ([ACP]) domain.

8839:RHO
gene id: 8839:RHO
uniprot id: A0A8B9TPD2
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Contains one covalently linked retinal chromophore.
messages: Membrane

8839:NFYA
gene id: 8839:NFYA
uniprot id: A0A8B9TR73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NFYA/HAP2 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
messages: Heterotrimer.
messages: Nucleus

8839:FGF13
gene id: 8839:FGF13
uniprot id: R0KY24
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8839:TGM4
gene id: 8839:TGM4
uniprot id: A0A8B9ZBF7
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

8839:LOC101796052
gene id: 8839:LOC101796052
uniprot id: A0A089G6D2
uniprot id: A0A915Y4P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Has antiviral activities.
messages: Secreted

8839:TAT
gene id: 8839:TAT
uniprot id: R0KNP9
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

8839:MAPK1
gene id: 8839:MAPK1
uniprot id: A0A076G731
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

8839:CCL20
gene id: 8839:CCL20
uniprot id: A0A8B9TB73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

8839:PPARA
gene id: 8839:PPARA
uniprot id: A0A8B9SM95
uniprot id: A5HJM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

8839:CRYZ
gene id: 8839:CRYZ
uniprot id: R0JVP4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

8839:PLIN2
gene id: 8839:PLIN2
uniprot id: A9YVJ0
names: Similarity
messages: Belongs to the perilipin family.

8839:FIGNL1
gene id: 8839:FIGNL1
uniprot id: R0JPA3
names: Similarity
messages: Belongs to the AAA ATPase family.

8839:EZH2
gene id: 8839:EZH2
uniprot id: A0A8B9T753
names: Subcellular Location Annotation
messages: Nucleus

8839:CACNG2
gene id: 8839:CACNG2
uniprot id: R0K2U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

8839:DPT
gene id: 8839:DPT
uniprot id: R0KYN8
names: Similarity
messages: Belongs to the dermatopontin family.

8839:RPS7
gene id: 8839:RPS7
uniprot id: A0A8B9SIY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eS7 family.
messages: centrosome

8839:CPT1A
gene id: 8839:CPT1A
uniprot id: R0L018
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

8839:NOL10
gene id: 8839:NOL10
uniprot id: A0A8B9QWB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat NOL10/ENP2 family.
messages: nucleolus

8839:STX19
gene id: 8839:STX19
uniprot id: R0LLM7
names: Similarity
messages: Belongs to the syntaxin family.

8839:CHST1
gene id: 8839:CHST1
uniprot id: R0LID9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

8839:DCLRE1A
gene id: 8839:DCLRE1A
uniprot id: R0LHF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

8839:GPR65
gene id: 8839:GPR65
uniprot id: A0A8B9SLI5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8839:PARK7
gene id: 8839:PARK7
uniprot id: R0KXC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C56 family.
messages: Membrane raft

8839:GJA4
gene id: 8839:GJA4
uniprot id: R0JIT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8839:CNRIP1
gene id: 8839:CNRIP1
uniprot id: R0L7A2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CNRIP family.
messages: Interacts with the cannabinoid receptor CNR1 (via C-terminus). Does not interact with cannabinoid receptor CNR2.
messages: Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels.

8839:LOC101797182
gene id: 8839:LOC101797182
uniprot id: A0A8B9R125
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8839:DDT
gene id: 8839:DDT
uniprot id: R0LA79
names: Similarity
messages: Belongs to the MIF family.

8839:ELOVL5
gene id: 8839:ELOVL5
uniprot id: A0A068C605
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL5 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: dendrite

8839:ZMPSTE24
gene id: 8839:ZMPSTE24
uniprot id: A0A8B9TGF7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.

8839:TAFA4
gene id: 8839:TAFA4
uniprot id: A0A8B9TG61
names: Similarity
messages: Belongs to the TAFA family.

8839:LOC101790517
gene id: 8839:LOC101790517
uniprot id: A0A8B9ZI60
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

8839:LOC101795838
gene id: 8839:LOC101795838
uniprot id: R0JVT9
names: Similarity
messages: Belongs to the pancreatic ribonuclease family.

8839:SAA2
gene id: 8839:SAA2
uniprot id: P02740
names: Disease Annotation
names: Function
names: Induction
names: PTM
names: Polymorphism
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: At least two alleles exist. The sequence of the B allele is shown here.
messages: Belongs to the SAA family.
messages: Expressed by the liver; secreted in plasma. Also present in the liver and lung irrespective of induction.
messages: Major acute phase reactant. Apolipoprotein of the HDL complex.
messages: Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function.
messages: Secreted
messages: This protein is the precursor of amyloid protein A, which is formed by the removal of approximately 3 residues from the C-terminal end.
messages: Upon cytokine stimulation.

8839:MRPS17
gene id: 8839:MRPS17
uniprot id: R0KD36
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

8839:RIPOR2
gene id: 8839:RIPOR2
uniprot id: A0A8B9SU96
names: Similarity
messages: Belongs to the RIPOR family.

8839:DHRS9
gene id: 8839:DHRS9
uniprot id: A0A8B9ZGN4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8839:MAT1A
gene id: 8839:MAT1A
uniprot id: R0LR17
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

8839:DRD1
gene id: 8839:DRD1
uniprot id: I6Q8X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8839:GPR87
gene id: 8839:GPR87
uniprot id: A0A8B9TJJ8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8839:CMBL
gene id: 8839:CMBL
uniprot id: R0L8L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dienelactone hydrolase family.
messages: cytosol

8839:PLAU
gene id: 8839:PLAU
uniprot id: A0A8B9ZI57
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8839:GOLGA5
gene id: 8839:GOLGA5
uniprot id: R0JRZ4
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport.

8839:TLR7
gene id: 8839:TLR7
uniprot id: A9X7P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Endoplasmic reticulum membrane
messages: Lysosome
messages: Membrane
messages: phagosome

8839:NCF2
gene id: 8839:NCF2
uniprot id: A0A8B9Z8G3
names: Similarity
messages: Belongs to the NCF2/NOXA1 family.

8839:LOC101793166
gene id: 8839:LOC101793166
uniprot id: Q38HW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

8839:TLR1-A
gene id: 8839:TLR1-A
uniprot id: M9NJN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8839:BMP4
gene id: 8839:BMP4
uniprot id: A5HMF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

8839:KEG62 p03
gene id: 8839:KEG62_p03
uniprot id: A6ZJ09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

8839:YPEL2
gene id: 8839:YPEL2
uniprot id: A0A8B9TSM1
names: Similarity
messages: Belongs to the yippee family.

8839:TTC39C
gene id: 8839:TTC39C
uniprot id: A0A8B9SPR2
names: Similarity
messages: Belongs to the TTC39 family.

8839:CACNB2
gene id: 8839:CACNB2
uniprot id: A0A8B9SFE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: sarcolemma

8839:NTRK3
gene id: 8839:NTRK3
uniprot id: A0A8B9SGX7
uniprot id: A0A8B9SGY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

8839:FGF9
gene id: 8839:FGF9
uniprot id: R0J7C8
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8839:LOC101802312
gene id: 8839:LOC101802312
uniprot id: A0A8B9QKT2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted

8839:GPR1
gene id: 8839:GPR1
uniprot id: A0A8B9QTU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

8839:UBL3
gene id: 8839:UBL3
uniprot id: A0A8B9R0E7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8839:FAR2
gene id: 8839:FAR2
uniprot id: A0A8B9SK50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acyl-CoA reductase family.
messages: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
messages: Peroxisome membrane

8839:HOXD11
gene id: 8839:HOXD11
uniprot id: A0A8B9SJX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8839:RGS4
gene id: 8839:RGS4
uniprot id: A0A8B9TFY3
names: Function
messages: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein.

8839:NDC80
gene id: 8839:NDC80
uniprot id: A0A8B9TRY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the NDC80/HEC1 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

8839:NADK
gene id: 8839:NADK
uniprot id: A0A8B9THS8
names: Similarity
messages: Belongs to the NAD kinase family.

8839:TBC1D7
gene id: 8839:TBC1D7
uniprot id: A0A8B9ZJY2
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Vesicle

8839:PDE8A
gene id: 8839:PDE8A
uniprot id: A0A8B9ZKR9
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8839:PDE6H
gene id: 8839:PDE6H
uniprot id: A0A8B9R0J7
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

8839:LOC101791292
gene id: 8839:LOC101791292
uniprot id: A0A8B9T8F3
uniprot id: A0A8B9TA28
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

8839:FAM167A
gene id: 8839:FAM167A
uniprot id: R0KZW7
names: Similarity
messages: Belongs to the FAM167 (SEC) family.

8839:LOC101792344
gene id: 8839:LOC101792344
uniprot id: A0A8B9ZKT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8839:PTGFR
gene id: 8839:PTGFR
uniprot id: R0KCM1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8839:LOC101797297
gene id: 8839:LOC101797297
uniprot id: A0A8B9TBU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

8839:IL15
gene id: 8839:IL15
uniprot id: A0A7S9TS10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-15/IL-21 family.
messages: Secreted

8839:LOC101804644
gene id: 8839:LOC101804644
uniprot id: R0LH27
names: Similarity
messages: Belongs to the TFIIE alpha subunit family.

8839:ABCC9
gene id: 8839:ABCC9
uniprot id: A0A8B9SRM1
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with KCNJ11.
messages: Membrane

8839:TH
gene id: 8839:TH
uniprot id: R0JUR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
messages: axon
messages: perinuclear region

8839:F2RL3
gene id: 8839:F2RL3
uniprot id: A0A8B9ZJV4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8839:KBP
gene id: 8839:KBP
uniprot id: Q90218
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists (By similarity).

8839:ZEB2
gene id: 8839:ZEB2
uniprot id: A0A8B9T699
names: Similarity
messages: Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.

8839:LOC101797138
gene id: 8839:LOC101797138
uniprot id: R0KET6
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

8839:GRPR
gene id: 8839:GRPR
uniprot id: R0K6D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8839:TAFA1
gene id: 8839:TAFA1
uniprot id: A0A8B9ZHZ8
names: Similarity
messages: Belongs to the TAFA family.

8839:SEMA3C
gene id: 8839:SEMA3C
uniprot id: A0A8B9R497
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8839:BRD1
gene id: 8839:BRD1
uniprot id: R0L443
names: Subcellular Location Annotation
messages: Nucleus

8839:RBP7
gene id: 8839:RBP7
uniprot id: R0L522
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8839:ANAPC13
gene id: 8839:ANAPC13
uniprot id: R0JW70
names: Function
names: Similarity
messages: Belongs to the APC13 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

8839:PABIR2
gene id: 8839:PABIR2
uniprot id: A0A8B9T849
names: Similarity
messages: Belongs to the FAM122 family.

8839:LSM14A
gene id: 8839:LSM14A
uniprot id: A0A023PUY5
names: Similarity
messages: Belongs to the LSM14 family.

8839:LHFPL2
gene id: 8839:LHFPL2
uniprot id: R0M4R0
names: Subcellular Location Annotation
messages: Membrane

8839:CTSK
gene id: 8839:CTSK
uniprot id: A0A8B9ZGA0
names: Similarity
messages: Belongs to the peptidase C1 family.

8839:KEG62 p10
gene id: 8839:KEG62_p10
uniprot id: A6ZJ02
uniprot id: P98019
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Binds a dinuclear copper A center per subunit.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)) (By similarity). Found in a complex with TMEM177, COA6, COX18, COX20, SCO1 and SCO2. Interacts with TMEM177 in a COX20-dependent manner. Interacts with COX20. Interacts with COX16 (By similarity).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

8839:SLC16A12
gene id: 8839:SLC16A12
uniprot id: R0JB22
names: Subcellular Location Annotation
messages: Membrane

8839:TMEM126A
gene id: 8839:TMEM126A
uniprot id: R0LJC4
names: Subcellular Location Annotation
messages: Membrane

8839:CCL26
gene id: 8839:CCL26
uniprot id: Q4VSK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

8839:ERGIC2
gene id: 8839:ERGIC2
uniprot id: A0A8B9SXP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

8839:SEC23A
gene id: 8839:SEC23A
uniprot id: R0L318
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

8839:GSN
gene id: 8839:GSN
uniprot id: R0L173
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the villin/gelsolin family.
messages: Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis.
messages: cytoskeleton

8839:CETP
gene id: 8839:CETP
uniprot id: S4SLP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Secreted

8839:CASP3
gene id: 8839:CASP3
uniprot id: A0A8B9SSZ4
names: Similarity
messages: Belongs to the peptidase C14A family.

8839:OGN
gene id: 8839:OGN
uniprot id: R0L6G4
names: Similarity
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.

8839:CA7
gene id: 8839:CA7
uniprot id: A0A8B9SKU2
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

8839:SPECC1L
gene id: 8839:SPECC1L
uniprot id: A0A8B9QZM4
uniprot id: R0KYM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytospin-A family.
messages: Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration.
messages: May interact with both microtubules and actin cytoskeleton.
messages: cytoskeleton
messages: gap junction
messages: spindle

8839:IL8
gene id: 8839:IL8
uniprot id: Q0WZB5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Homodimer.
messages: Secreted

8839:FAM120B
gene id: 8839:FAM120B
uniprot id: A0A8B9SGK3
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

8839:EHD4
gene id: 8839:EHD4
uniprot id: R0J902
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

8839:NR1H3
gene id: 8839:NR1H3
uniprot id: C5IUM7
uniprot id: R0KNX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

8839:IL10
gene id: 8839:IL10
uniprot id: I6N8I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

8839:EXTL2
gene id: 8839:EXTL2
uniprot id: A0A8B9TLH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

8839:NFYB
gene id: 8839:NFYB
uniprot id: A0A8B9TXA9
names: Function
names: Similarity
messages: Belongs to the NFYB/HAP3 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.

8839:PTH
gene id: 8839:PTH
uniprot id: A0A8B9T173
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion.
messages: Secreted

8839:TRAF3
gene id: 8839:TRAF3
uniprot id: R0JSP4
names: Subcellular Location Annotation
messages: Cytoplasm

8839:ADCY7
gene id: 8839:ADCY7
uniprot id: A0A8B9QZN7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

8839:CYGB
gene id: 8839:CYGB
uniprot id: R0K683
names: Similarity
messages: Belongs to the globin family.

8839:LOC101795902
gene id: 8839:LOC101795902
uniprot id: A0A8B9R150
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

8839:HSPA2
gene id: 8839:HSPA2
uniprot id: B2ZP77
names: Similarity
messages: Belongs to the heat shock protein 70 family.

8839:LOC101795539
gene id: 8839:LOC101795539
uniprot id: A0A8B9TBT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-microseminoprotein family.
messages: Secreted

8839:LOC101802760
gene id: 8839:LOC101802760
uniprot id: A0A0C4WVM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8839:LOC101791691
gene id: 8839:LOC101791691
uniprot id: R0M3S3
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

8839:TNFSF8
gene id: 8839:TNFSF8
uniprot id: A0A8B9TNY3
names: Similarity
messages: Belongs to the tumor necrosis factor family.

8839:RCAN2
gene id: 8839:RCAN2
uniprot id: R0KKK3
names: Function
names: Similarity
messages: Belongs to the RCAN family.
messages: Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.

8839:KEG62 p08
gene id: 8839:KEG62_p08
uniprot id: A6ZJ04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
messages: Mitochondrion inner membrane

8839:HOXD10
gene id: 8839:HOXD10
uniprot id: A0A8B9SJS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8839:SLC6A19
gene id: 8839:SLC6A19
uniprot id: A0A088MGN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8839:ARMC1
gene id: 8839:ARMC1
uniprot id: R0L473
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.
messages: Membrane
messages: Mitochondrion outer membrane

8839:GPHB5
gene id: 8839:GPHB5
uniprot id: R0JNV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

8839:HOXD4
gene id: 8839:HOXD4
uniprot id: A0A8B9SJM7
uniprot id: R0K7E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

8839:LDAH
gene id: 8839:LDAH
uniprot id: A0A8B9QUF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. LDAH family.
messages: Lipid droplet

8839:FTH1
gene id: 8839:FTH1
uniprot id: P80145
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Belongs to the ferritin family.
messages: By duck hepatitis virus type I (DHV-1) (PubMed:24981929). By polyinosinic:polycytidylic acid (poly I:C) which mimicks viral double-stranded RNA (PubMed:1499559).
messages: Cytoplasm
messages: Expressed in erythroblasts (at protein level) (PubMed:1499559). Expressed in heart, liver, spleen, lung, kidney, large intestine, small intestine, muscle, glandular stomach, ovary and oviduct (PubMed:24981929).
messages: Inhibits translation of various mRNA species in vitro. Associates with a 35S prosome-like particle that contains non-translated mRNAs in a complex with proteins. May be involved in pre-translational regulation of some mRNA.
messages: Oligomer of 24 subunits. There are two types of subunits: L (light) chain and H (heavy) chain. The major chain can be light or heavy, depending on the species and tissue type. The functional molecule forms a roughly spherical shell with a diameter of 12 nm and contains a central cavity into which the insoluble mineral iron core is deposited.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney.

8839:LOC101804190
gene id: 8839:LOC101804190
uniprot id: A0A8B9TQH4
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8839:GNPDA2
gene id: 8839:GNPDA2
uniprot id: A0A8B9QR64
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

8839:CAV3
gene id: 8839:CAV3
uniprot id: D7RF71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

8839:KEG62 p01
gene id: 8839:KEG62_p01
uniprot id: A6ZJ11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion membrane

8839:ASL
gene id: 8839:ASL
uniprot id: P24057
names: Function
names: Similarity
names: Subunit
names: Tissue Specificity
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Delta crystallin, the principal crystallin in embryonic lens, is found only in birds and reptiles. Despite possessing the necessary catalytic residues, this protein does not function as an enzymatically active argininosuccinate lyase.
messages: Eye lens.
messages: Homotetramer.

8839:DOCK2
gene id: 8839:DOCK2
uniprot id: A0A8B9T599
names: Similarity
messages: Belongs to the DOCK family.

8839:SLA
gene id: 8839:SLA
uniprot id: A0A8B9TBV5
names: Subcellular Location Annotation
messages: Cytoplasm

8839:LOC101795858
gene id: 8839:LOC101795858
uniprot id: A0A8B9ZGT4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8839:PDCL
gene id: 8839:PDCL
uniprot id: R0JBI8
names: Similarity
messages: Belongs to the phosducin family.

8839:ADIPOR1
gene id: 8839:ADIPOR1
uniprot id: Q09LK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8839:STXBP3
gene id: 8839:STXBP3
uniprot id: A0A8B9SJ47
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

8839:PRPF3
gene id: 8839:PRPF3
uniprot id: R0KYC6
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).

8839:FBXO32
gene id: 8839:FBXO32
uniprot id: E5FXJ0
names: Subcellular Location Annotation
messages: Nucleus

8839:KEG62 p02
gene id: 8839:KEG62_p02
uniprot id: A6ZJ10
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
messages: Membrane
messages: Mitochondrion inner membrane

8839:NT5C3A
gene id: 8839:NT5C3A
uniprot id: A0A8B9ZKJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

8839:CLDN14
gene id: 8839:CLDN14
uniprot id: R0LWV6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8839:RPRD1A
gene id: 8839:RPRD1A
uniprot id: A0A8B9SGM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0400 (RTT103) family.
messages: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle.
messages: Nucleus

8839:LOC101798172
gene id: 8839:LOC101798172
uniprot id: A0A8B9R0U8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8839:TADA2A
gene id: 8839:TADA2A
uniprot id: A0A8B9TNC9
names: Subcellular Location Annotation
messages: Nucleus

8839:LOC101799614
gene id: 8839:LOC101799614
uniprot id: R0JN79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcitonin family.
messages: Secreted

8839:KCNG4
gene id: 8839:KCNG4
uniprot id: A0A8B9T105
names: Subcellular Location Annotation
messages: Membrane

8839:LOC101790354
gene id: 8839:LOC101790354
uniprot id: A0A8B9QZR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

8839:RRH
gene id: 8839:RRH
uniprot id: R0JUG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8839:RARB
gene id: 8839:RARB
uniprot id: A0A8B9TJH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

8839:MTMR9
gene id: 8839:MTMR9
uniprot id: R0KZW3
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

8839:CDKN1B
gene id: 8839:CDKN1B
uniprot id: Q6QWC3
names: Similarity
messages: Belongs to the CDI family.

8839:CDC42EP3
gene id: 8839:CDC42EP3
uniprot id: A0A8B9SZR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

8839:PCYT1A
gene id: 8839:PCYT1A
uniprot id: R0L7H3
names: Function
names: Similarity
messages: Belongs to the cytidylyltransferase family.
messages: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.

8839:RPL19
gene id: 8839:RPL19
uniprot id: S4V6M7
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Component of the large ribosomal subunit.

8839:LOC101795677
gene id: 8839:LOC101795677
uniprot id: A0A8B9T4E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8839:AMH
gene id: 8839:AMH
uniprot id: Q0P6K6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Secreted

8839:CAV1
gene id: 8839:CAV1
uniprot id: D7RF70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

8839:TSHZ2
gene id: 8839:TSHZ2
uniprot id: A0A8B9TMK3
names: Similarity
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.

8839:LOC101798456
gene id: 8839:LOC101798456
uniprot id: A0A8B9SQM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIP family.
messages: adherens junction
messages: centriolar satellite

8839:TRAK2
gene id: 8839:TRAK2
uniprot id: A0A8B9T134
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the milton family.
messages: Early endosome
messages: Mitochondrion

8839:SLC5A3
gene id: 8839:SLC5A3
uniprot id: R0K5X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8839:KLHL40
gene id: 8839:KLHL40
uniprot id: R0JMM7
names: Similarity
names: Subcellular Location Annotation
messages: A band
messages: Belongs to the KLHL40 family.
messages: I band

8839:IFITM1
gene id: 8839:IFITM1
uniprot id: A0A0C4K292
names: Similarity
messages: Belongs to the CD225/Dispanin family.

8839:LITAF
gene id: 8839:LITAF
uniprot id: R0KR32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

8839:GYS2
gene id: 8839:GYS2
uniprot id: R0LET4
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

8839:HDAC10
gene id: 8839:HDAC10
uniprot id: A0A8B9TL37
names: Similarity
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.

8839:POMT1
gene id: 8839:POMT1
uniprot id: A0A8B9ZF33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

8839:IL17A
gene id: 8839:IL17A
uniprot id: B0FYQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

8839:DYDC1
gene id: 8839:DYDC1
uniprot id: A0A8B9TG86
names: Similarity
messages: Belongs to the dpy-30 family.

8839:LOC101796851
gene id: 8839:LOC101796851
uniprot id: A0A8B9T9I6
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

8839:HOXB5
gene id: 8839:HOXB5
uniprot id: A0A8B9SH00
uniprot id: R0L8J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

8839:MYOG
gene id: 8839:MYOG
uniprot id: E5CYI9
names: Subcellular Location Annotation
messages: Nucleus

8839:GPR146
gene id: 8839:GPR146
uniprot id: R0LKI7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8839:TRPM5
gene id: 8839:TRPM5
uniprot id: A0A8B9R3K9
names: Subcellular Location Annotation
messages: Membrane

8839:EPHA7
gene id: 8839:EPHA7
uniprot id: A0A8B9T9N8
uniprot id: R0M1N5
names: Subcellular Location Annotation
messages: Membrane

8839:SNX20
gene id: 8839:SNX20
uniprot id: R0LE57
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Membrane

8839:FIGN
gene id: 8839:FIGN
uniprot id: A0A8B9TW69
names: Similarity
messages: Belongs to the AAA ATPase family.

8839:LOC101793493
gene id: 8839:LOC101793493
uniprot id: Q8UWE2
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8839:HDC
gene id: 8839:HDC
uniprot id: A0A8B9TV17
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

8839:SEC22A
gene id: 8839:SEC22A
uniprot id: R0LM61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in vesicle transport between the ER and the Golgi complex.
messages: Membrane

8839:IRF8
gene id: 8839:IRF8
uniprot id: Q0ZQ58
names: Subcellular Location Annotation
messages: Nucleus

8839:TNFSF15
gene id: 8839:TNFSF15
uniprot id: R0LCQ5
names: Similarity
messages: Belongs to the tumor necrosis factor family.

8839:CCNE2
gene id: 8839:CCNE2
uniprot id: A0A8B9R8X6
names: Similarity
messages: Belongs to the cyclin family.

8839:FUT10
gene id: 8839:FUT10
uniprot id: A0A8B9R0I9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane
messages: Probable fucosyltransferase.

8839:MC1R
gene id: 8839:MC1R
uniprot id: G0XMW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

8839:SNTB1
gene id: 8839:SNTB1
uniprot id: R0JVY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

8839:CAP2
gene id: 8839:CAP2
uniprot id: R0JNL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAP family.
messages: Cell membrane

8839:GHR
gene id: 8839:GHR
uniprot id: C7DY43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Cell membrane
messages: The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.

8839:NFE2L2
gene id: 8839:NFE2L2
uniprot id: A0A088MGY0
names: Similarity
messages: Belongs to the bZIP family. CNC subfamily.

8839:CEPT1
gene id: 8839:CEPT1
uniprot id: R0JFZ2
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

8839:ZNF622
gene id: 8839:ZNF622
uniprot id: R0M156
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the REI1 family.
messages: Cytoplasm

8839:AGPAT5
gene id: 8839:AGPAT5
uniprot id: R0M4A0
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8839:LIMK2
gene id: 8839:LIMK2
uniprot id: A0A8B9SMZ3
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

8839:LOC101796828
gene id: 8839:LOC101796828
uniprot id: A0A8B9TRF4
names: Subcellular Location Annotation
messages: Membrane

8839:MIEF1
gene id: 8839:MIEF1
uniprot id: R0JDV1
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

8839:TSPAN7
gene id: 8839:TSPAN7
uniprot id: A0A8B9T7K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8839:LOC101802880
gene id: 8839:LOC101802880
uniprot id: A0A8B9QVT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dienelactone hydrolase family.
messages: cytosol

8839:MINAR1
gene id: 8839:MINAR1
uniprot id: R0KJZ6
names: Similarity
messages: Belongs to the MINAR family.

8839:TUBB1
gene id: 8839:TUBB1
uniprot id: A0A8B9SJR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

8839:ARHGEF6
gene id: 8839:ARHGEF6
uniprot id: R0JLG7
names: Subcellular Location Annotation
messages: lamellipodium

8839:ABHD2
gene id: 8839:ABHD2
uniprot id: A0A8B9QUB7
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

8839:PSKH1
gene id: 8839:PSKH1
uniprot id: R0JAC2
names: Similarity
messages: Belongs to the protein kinase superfamily.

8839:RAP2A
gene id: 8839:RAP2A
uniprot id: R0L5P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

8839:ST6GAL1
gene id: 8839:ST6GAL1
uniprot id: R0JBS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8839:LCAT
gene id: 8839:LCAT
uniprot id: Q9DDJ6
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

8839:TMEM19
gene id: 8839:TMEM19
uniprot id: A0A8B9SGH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

8839:RFFL
gene id: 8839:RFFL
uniprot id: R0LQ56
names: Subcellular Location Annotation
messages: Cell membrane

8839:LOC101799119
gene id: 8839:LOC101799119
uniprot id: R0LBP6
names: Similarity
messages: Belongs to the serpin family.

8839:TTR
gene id: 8839:TTR
uniprot id: Q2LDE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transthyretin family.
messages: Homotetramer.
messages: Secreted
messages: Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.

8839:LOC101802994
gene id: 8839:LOC101802994
uniprot id: A0A8B9SY46
names: Similarity
messages: Belongs to the FBPase class 1 family.

8839:XPO1
gene id: 8839:XPO1
uniprot id: A0A8B9T4L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm

8839:HSD17B2
gene id: 8839:HSD17B2
uniprot id: R0LKH5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8839:PPARG
gene id: 8839:PPARG
uniprot id: A5HNY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Cytoplasm
messages: Heterodimer with other nuclear receptors.
messages: Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. May play a role in the regulation of circadian rhythm.
messages: Nucleus

8839:ADGRD1
gene id: 8839:ADGRD1
uniprot id: R0JXN5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8839:EXOC2
gene id: 8839:EXOC2
uniprot id: A0A8B9T0V9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SEC5 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: Component of the exocyst complex.

8839:LOC101794119
gene id: 8839:LOC101794119
uniprot id: A0A8B9QTP4
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

8839:GJD2
gene id: 8839:GJD2
uniprot id: R0M753
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8839:LOC110351185
gene id: 8839:LOC110351185
uniprot id: C7AFF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
messages: Membrane

8839:LOC101799748
gene id: 8839:LOC101799748
uniprot id: A0A8B9R0A2
names: Similarity
messages: Belongs to the DeSI family.

8839:PRKCZ
gene id: 8839:PRKCZ
uniprot id: A0A8B9TIB7
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

8839:ATP6V0D2
gene id: 8839:ATP6V0D2
uniprot id: A0A8B9SNQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

8839:SLC2A8
gene id: 8839:SLC2A8
uniprot id: A0A8B9R0J2
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8839:C12H19orf12
gene id: 8839:C12H19orf12
uniprot id: A0A8B9TGU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the C19orf12 family.
messages: Mitochondrion membrane

8839:LOC101803572
gene id: 8839:LOC101803572
uniprot id: R0LHU9
names: Similarity
messages: Belongs to the serpin family.

8839:VANGL1
gene id: 8839:VANGL1
uniprot id: A0A8B9SQ27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

8839:TLR3
gene id: 8839:TLR3
uniprot id: A0A0A0V0T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8839:UPP1
gene id: 8839:UPP1
uniprot id: A0A8B9R2P5
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

8839:THYN1
gene id: 8839:THYN1
uniprot id: A0A8B9T216
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

8839:JAKMIP1
gene id: 8839:JAKMIP1
uniprot id: A0A8B9SP89
names: Similarity
messages: Belongs to the JAKMIP family.

8839:CEBPG
gene id: 8839:CEBPG
uniprot id: R0JU53
names: Similarity
messages: Belongs to the bZIP family. C/EBP subfamily.

8839:LOC101796665
gene id: 8839:LOC101796665
uniprot id: A0A8B9QYB5
names: Subcellular Location Annotation
messages: Membrane

8839:HENMT1
gene id: 8839:HENMT1
uniprot id: R0JDI5
names: Similarity
messages: Belongs to the methyltransferase superfamily. HEN1 family.

8839:SPARC
gene id: 8839:SPARC
uniprot id: A0A8B9SQ92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
messages: Belongs to the SPARC family.
messages: Membrane
messages: basement membrane

8839:FGF12
gene id: 8839:FGF12
uniprot id: A0A8B9T793
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8839:ACTA2
gene id: 8839:ACTA2
uniprot id: A0A8B9TDD8
names: Similarity
messages: Belongs to the actin family.

8839:NOG
gene id: 8839:NOG
uniprot id: R0LLV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the noggin family.
messages: Secreted

8839:LOC101791654
gene id: 8839:LOC101791654
uniprot id: R0L5N3
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

8839:DHRS7
gene id: 8839:DHRS7
uniprot id: A0A8B9ZAW0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8839:TLR5
gene id: 8839:TLR5
uniprot id: V9XUA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8839:BCL2A1
gene id: 8839:BCL2A1
uniprot id: R0KRS9
names: Similarity
messages: Belongs to the Bcl-2 family.

8839:RSAD2
gene id: 8839:RSAD2
uniprot id: A0A0B5JQU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RSAD2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8839:HECTD1
gene id: 8839:HECTD1
uniprot id: A0A8B9TUS2
names: Function
names: Similarity
messages: Belongs to the UPL family. K-HECT subfamily.
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

8839:NOP14
gene id: 8839:NOP14
uniprot id: R0LDU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP14 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
messages: nucleolus

8839:SLC35A3
gene id: 8839:SLC35A3
uniprot id: A0A8B9TN86
uniprot id: A0A8B9TNE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8839:TEKT3
gene id: 8839:TEKT3
uniprot id: R0JIS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

8839:TENT5D
gene id: 8839:TENT5D
uniprot id: A0A8B9TRE7
names: Similarity
messages: Belongs to the TENT family.

8839:MDFIC
gene id: 8839:MDFIC
uniprot id: A0A8B9ZJS6
names: Similarity
messages: Belongs to the MDFI family.

8839:DKK2
gene id: 8839:DKK2
uniprot id: R0LL40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

8839:ERRFI1
gene id: 8839:ERRFI1
uniprot id: R0JKY1
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus

8839:STAMBPL1
gene id: 8839:STAMBPL1
uniprot id: A0A8B9TBB8
names: Similarity
messages: Belongs to the peptidase M67C family.

8839:PSPH
gene id: 8839:PSPH
uniprot id: R0LQ88
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

8839:INHBA
gene id: 8839:INHBA
uniprot id: R0LSN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

8839:FYN
gene id: 8839:FYN
uniprot id: R0JAE7
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8839:KIN
gene id: 8839:KIN
uniprot id: A0A8B9R1X8
names: Similarity
messages: Belongs to the KIN17 family.

8839:SLC6A12
gene id: 8839:SLC6A12
uniprot id: R0LZH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8839:ZDHHC22
gene id: 8839:ZDHHC22
uniprot id: R0K5U8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8839:NIT2
gene id: 8839:NIT2
uniprot id: A0A8B9R6T2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

8839:NMUR2
gene id: 8839:NMUR2
uniprot id: R0L5B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

8839:MEOX2
gene id: 8839:MEOX2
uniprot id: A0A8B9SHC2
uniprot id: R0K3I0
names: Subcellular Location Annotation
messages: Nucleus

8839:CAVIN4
gene id: 8839:CAVIN4
uniprot id: A0A8B9SWW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

8839:DCN
gene id: 8839:DCN
uniprot id: R0LLK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: Binds to type I and type II collagen, fibronectin and TGF-beta. Forms a ternary complex with MFAP2 and ELN.
messages: May affect the rate of fibrils formation.
messages: extracellular matrix

8839:PDP2
gene id: 8839:PDP2
uniprot id: A0A8B9SKN7
names: Similarity
messages: Belongs to the PP2C family.

8839:LOC101796420
gene id: 8839:LOC101796420
uniprot id: R0LUG4
names: Similarity
messages: Belongs to the cytochrome P450 family.

8839:SERPINH1
gene id: 8839:SERPINH1
uniprot id: R0JPJ8
names: Function
names: Similarity
messages: Belongs to the serpin family.
messages: Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.

8839:LOC101801574
gene id: 8839:LOC101801574
uniprot id: A0A8B9T4A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8839:HOXA6
gene id: 8839:HOXA6
uniprot id: A0A8B9QNS9
uniprot id: R0LGR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

8839:LOC101798290
gene id: 8839:LOC101798290
uniprot id: R0J7H7
names: Similarity
messages: Belongs to the globin family.

8839:RAB19
gene id: 8839:RAB19
uniprot id: A0A8B9TYN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane

8839:IFITM10
gene id: 8839:IFITM10
uniprot id: A0A0C4K5J3
names: Similarity
messages: Belongs to the CD225/Dispanin family.

8839:LOC101790670
gene id: 8839:LOC101790670
uniprot id: Q04791
names: Function
names: Similarity
names: Tissue Specificity
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Fatty acid biosynthesis chain termination and release of the free fatty acid product is achieved by hydrolysis of the thio ester by a thioesterase. This thioesterase may be associated with peroxisome proliferation and may play a role in the production of 3-hydroxy fatty acid diester pheromones.
messages: Highest levels in uropygial gland, much lower in liver and kidney.

8839:TSHB
gene id: 8839:TSHB
uniprot id: Q2Q1W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

8839:FGFBP2
gene id: 8839:FGFBP2
uniprot id: R0LBY3
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

8839:GPX7
gene id: 8839:GPX7
uniprot id: R0JF99
names: Similarity
messages: Belongs to the glutathione peroxidase family.

8839:KPNA2
gene id: 8839:KPNA2
uniprot id: R0M1W9
names: Similarity
messages: Belongs to the importin alpha family.

8839:VTI1A
gene id: 8839:VTI1A
uniprot id: A0A8B9SSE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

8839:CD8A
gene id: 8839:CD8A
uniprot id: J7FMN6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8839:ADPRHL1
gene id: 8839:ADPRHL1
uniprot id: A0A8B9SIJ3
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

8839:LOC101790267
gene id: 8839:LOC101790267
uniprot id: I6V7Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

8839:LOC101790527
gene id: 8839:LOC101790527
uniprot id: R0JUF1
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

8839:SPON2
gene id: 8839:SPON2
uniprot id: R0K2H0
names: Subcellular Location Annotation
messages: extracellular matrix

8839:AMER3
gene id: 8839:AMER3
uniprot id: R0LXF8
names: Similarity
messages: Belongs to the Amer family.

8839:KEG62 p12
gene id: 8839:KEG62_p12
uniprot id: Q7J4X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 2 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

8839:LOC101792508
gene id: 8839:LOC101792508
uniprot id: A0A8B9TUS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8839:VLDLR
gene id: 8839:VLDLR
uniprot id: G1D8U0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8839:GPR137B
gene id: 8839:GPR137B
uniprot id: A0A8B9TV76
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

8839:CHRM5
gene id: 8839:CHRM5
uniprot id: R0M314
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

8839:STK11
gene id: 8839:STK11
uniprot id: A0A8B9SWH7
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. LKB1 subfamily.

8839:CXXC5
gene id: 8839:CXXC5
uniprot id: A0A8B9TAK1
names: Subcellular Location Annotation
messages: Cytoplasm

8839:LYRM9
gene id: 8839:LYRM9
uniprot id: A0A8B9ZH21
names: Similarity
messages: Belongs to the complex I LYR family. LYRM9 subfamily.

8839:PLCB2
gene id: 8839:PLCB2
uniprot id: A0A8B9QRH3
uniprot id: A0A8B9SGS7
names: Cofactor
names: Function
messages: Binds 1 Ca(2+) ion per subunit.
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

8839:HOXA5
gene id: 8839:HOXA5
uniprot id: A0A8B9QQG2
uniprot id: R0L1L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

8839:PAX7
gene id: 8839:PAX7
uniprot id: I7FSJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

8839:GRIN1
gene id: 8839:GRIN1
uniprot id: Q91979
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8839:FGF23
gene id: 8839:FGF23
uniprot id: A0A8B9TA87
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8839:PDLIM3
gene id: 8839:PDLIM3
uniprot id: A0A8B9SRF7
uniprot id: A0A8B9ZCD2
names: Subcellular Location Annotation
messages: Z line

8839:LOC101799623
gene id: 8839:LOC101799623
uniprot id: A0A8B9TWX1
names: Subcellular Location Annotation
messages: Cell membrane
messages: invadopodium membrane
messages: lamellipodium membrane

8839:CPZ
gene id: 8839:CPZ
uniprot id: A0A8B9ZFR8
names: Caution
names: Similarity
messages: Belongs to the peptidase M14 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8839:LOC101792573
gene id: 8839:LOC101792573
uniprot id: A0A8B9QZP4
names: Similarity
messages: Belongs to the cytochrome P450 family.

8839:AQP1
gene id: 8839:AQP1
uniprot id: R0K8H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8839:AKIRIN2
gene id: 8839:AKIRIN2
uniprot id: G0TA26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

8839:ETFRF1
gene id: 8839:ETFRF1
uniprot id: R0JN64
names: Similarity
messages: Belongs to the complex I LYR family.

8839:MYF5
gene id: 8839:MYF5
uniprot id: D6BU30
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

8839:GABRA1
gene id: 8839:GABRA1
uniprot id: R0LMX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA1 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8839:SLC16A9
gene id: 8839:SLC16A9
uniprot id: R0LF40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cell membrane
messages: Membrane

8839:BET1L
gene id: 8839:BET1L
uniprot id: A0A8B9QUP7
names: Subcellular Location Annotation
messages: Membrane

8839:IFNG
gene id: 8839:IFNG
uniprot id: Q0MRR0
uniprot id: Q9YGB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II (or gamma) interferon family.
messages: Homodimer.
messages: Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
messages: Secreted

8839:BTBD10
gene id: 8839:BTBD10
uniprot id: A0A8B9T0I5
names: Subcellular Location Annotation
messages: Cytoplasm

8839:SUCNR1
gene id: 8839:SUCNR1
uniprot id: A0A8B9TJ60
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8839:C2H7orf25
gene id: 8839:C2H7orf25
uniprot id: A0A8B9R366
names: Similarity
messages: Belongs to the UPF0415 family.

8839:LOC101802682
gene id: 8839:LOC101802682
uniprot id: R0JP17
names: Similarity
messages: Belongs to the serpin family.

8839:KEG62 p06
gene id: 8839:KEG62_p06
uniprot id: A6ZJ06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I.
messages: Mitochondrion membrane

8839:LPAR3
gene id: 8839:LPAR3
uniprot id: A0A8B9ZCP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8839:LOC101798228
gene id: 8839:LOC101798228
uniprot id: R0LSB2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

8839:LOC101795719
gene id: 8839:LOC101795719
uniprot id: A0A8B9ZE04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARL2BP family.
messages: Cytoplasm
messages: Mitochondrion intermembrane space
messages: Nucleus
messages: Plays a role as an effector of the ADP-ribosylation factor-like protein 2, ARL2.
messages: centrosome
messages: cilium basal body

8839:CDK3
gene id: 8839:CDK3
uniprot id: A0A8B9ZGH0
names: Similarity
messages: Belongs to the protein kinase superfamily.

8839:LOC101803044
gene id: 8839:LOC101803044
uniprot id: A0A8B9Z9Z3
names: Subcellular Location Annotation
messages: Membrane

8839:P2RY8
gene id: 8839:P2RY8
uniprot id: A0A8B9QQ50
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8839:SLC16A1
gene id: 8839:SLC16A1
uniprot id: R0K776
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

8839:GCG
gene id: 8839:GCG
uniprot id: A0A8B9TVD6
names: Similarity
messages: Belongs to the glucagon family.

8839:PLA2R1
gene id: 8839:PLA2R1
uniprot id: A0A0D3RVN4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8839:TSPAN4
gene id: 8839:TSPAN4
uniprot id: A0A8B9TSJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8839:GDPD1
gene id: 8839:GDPD1
uniprot id: A0A8B9TRE4
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

8839:TPRA1
gene id: 8839:TPRA1
uniprot id: A0A8B9T1X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0359 family.
messages: Membrane

8839:FABP1
gene id: 8839:FABP1
uniprot id: A0A8B9SJJ1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport.
messages: Cytoplasm
messages: Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.

8839:LOC101795406
gene id: 8839:LOC101795406
uniprot id: A0A076FVB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lambda interferon family.
messages: Secreted

8839:PRKACB
gene id: 8839:PRKACB
uniprot id: R0JPM8
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.

8839:ATP1A1
gene id: 8839:ATP1A1
uniprot id: Q7ZYV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane

8839:NDST4
gene id: 8839:NDST4
uniprot id: R0L8A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

8839:TADA1
gene id: 8839:TADA1
uniprot id: A0A8B9ZIZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TADA1 family.
messages: Nucleus
messages: Probably involved in transcriptional regulation.

8839:LOC101790996
gene id: 8839:LOC101790996
uniprot id: R0JRB7
names: Similarity
messages: Belongs to the serpin family.

8839:PTHLH
gene id: 8839:PTHLH
uniprot id: A0A8B9SKY8
uniprot id: R0KD54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: Secreted

8839:ASPA
gene id: 8839:ASPA
uniprot id: R0JND7
names: Cofactor
names: Similarity
messages: Belongs to the AspA/AstE family. Aspartoacylase subfamily.
messages: Binds 1 zinc ion per subunit.

8839:LOC101804741
gene id: 8839:LOC101804741
uniprot id: A0A8B9TTK1
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8839:TXNL4B
gene id: 8839:TXNL4B
uniprot id: R0M356
names: Similarity
messages: Belongs to the DIM1 family.

8839:PBRM1
gene id: 8839:PBRM1
uniprot id: A0A8B9TJ89
uniprot id: R0JIY6
names: Subcellular Location Annotation
messages: Nucleus

8839:RPL17
gene id: 8839:RPL17
uniprot id: A0A8B9TX19
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

8839:WNT7B
gene id: 8839:WNT7B
uniprot id: R0M2F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix