880478:THESIDRAFT1 RS11625
gene id: 880478:THESIDRAFT1_RS11625
uniprot id: I9KW63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

880478:THESIDRAFT1 RS07300
gene id: 880478:THESIDRAFT1_RS07300
uniprot id: I8QZC6
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

880478:THESIDRAFT1 RS04415
gene id: 880478:THESIDRAFT1_RS04415
uniprot id: I8QY30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

880478:THESIDRAFT1 RS07495
gene id: 880478:THESIDRAFT1_RS07495
uniprot id: I9AEP2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

880478:THESIDRAFT1 RS04420
gene id: 880478:THESIDRAFT1_RS04420
uniprot id: I9KSM9
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

880478:THESIDRAFT1 RS03725
gene id: 880478:THESIDRAFT1_RS03725
uniprot id: I8R2Z9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

880478:THESIDRAFT1 RS10405
gene id: 880478:THESIDRAFT1_RS10405
uniprot id: I8R0Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

880478:THESIDRAFT1 RS03760
gene id: 880478:THESIDRAFT1_RS03760
uniprot id: I9ACN4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

880478:THESIDRAFT1 RS00810
gene id: 880478:THESIDRAFT1_RS00810
uniprot id: I9KQZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

880478:THESIDRAFT1 RS06145
gene id: 880478:THESIDRAFT1_RS06145
uniprot id: I8QYP6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

880478:THESIDRAFT1 RS02055
gene id: 880478:THESIDRAFT1_RS02055
uniprot id: I9KRF0
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

880478:THESIDRAFT1 RS11140
gene id: 880478:THESIDRAFT1_RS11140
uniprot id: I8R6G6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

880478:THESIDRAFT1 RS06880
gene id: 880478:THESIDRAFT1_RS06880
uniprot id: I8R4L9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS00680
gene id: 880478:THESIDRAFT1_RS00680
uniprot id: I9KQM6
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

880478:THESIDRAFT1 RS06205
gene id: 880478:THESIDRAFT1_RS06205
uniprot id: I8QYQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS06130
gene id: 880478:THESIDRAFT1_RS06130
uniprot id: I8R489
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

880478:THESIDRAFT1 RS08015
gene id: 880478:THESIDRAFT1_RS08015
uniprot id: I9KUD7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

880478:THESIDRAFT1 RS07655
gene id: 880478:THESIDRAFT1_RS07655
uniprot id: I8QZG5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

880478:THESIDRAFT1 RS11190
gene id: 880478:THESIDRAFT1_RS11190
uniprot id: I9KVX8
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

880478:THESIDRAFT1 RS06810
gene id: 880478:THESIDRAFT1_RS06810
uniprot id: I9AEA5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

880478:THESIDRAFT1 RS06070
gene id: 880478:THESIDRAFT1_RS06070
uniprot id: I8QYN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

880478:THESIDRAFT1 RS11945
gene id: 880478:THESIDRAFT1_RS11945
uniprot id: I9KWC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS02470
gene id: 880478:THESIDRAFT1_RS02470
uniprot id: I8QX70
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS04820
gene id: 880478:THESIDRAFT1_RS04820
uniprot id: I9KT43
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Binds 1 Fe(2+) ion per subunit. The iron ion 2 is coordinated via four histidines and one cysteine residue.
messages: Binds 1 Fe(3+) ion per subunit. The iron ion 1 is coordinated via 4 cysteine residues.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

880478:THESIDRAFT1 RS09605
gene id: 880478:THESIDRAFT1_RS09605
uniprot id: I9KV63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

880478:THESIDRAFT1 RS01395
gene id: 880478:THESIDRAFT1_RS01395
uniprot id: I9KR99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

880478:THESIDRAFT1 RS02160
gene id: 880478:THESIDRAFT1_RS02160
uniprot id: I9ABT5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS04880
gene id: 880478:THESIDRAFT1_RS04880
uniprot id: I9KSU1
names: Subcellular Location Annotation
messages: Nucleus

880478:THESIDRAFT1 RS12190
gene id: 880478:THESIDRAFT1_RS12190
uniprot id: I8R6Z9
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

880478:THESIDRAFT1 RS05750
gene id: 880478:THESIDRAFT1_RS05750
uniprot id: I8R422
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

880478:THESIDRAFT1 RS06230
gene id: 880478:THESIDRAFT1_RS06230
uniprot id: I8QYR0
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS03445
gene id: 880478:THESIDRAFT1_RS03445
uniprot id: I8QXK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

880478:THESIDRAFT1 RS11070
gene id: 880478:THESIDRAFT1_RS11070
uniprot id: I9KW83
names: Similarity
messages: Belongs to the CinA family.

880478:THESIDRAFT1 RS10930
gene id: 880478:THESIDRAFT1_RS10930
uniprot id: I8R0Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

880478:THESIDRAFT1 RS10075
gene id: 880478:THESIDRAFT1_RS10075
uniprot id: I8R626
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

880478:THESIDRAFT1 RS05870
gene id: 880478:THESIDRAFT1_RS05870
uniprot id: I8QYL0
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS00855
gene id: 880478:THESIDRAFT1_RS00855
uniprot id: I8QWB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

880478:THESIDRAFT1 RS05450
gene id: 880478:THESIDRAFT1_RS05450
uniprot id: I9KT36
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

880478:THESIDRAFT1 RS07635
gene id: 880478:THESIDRAFT1_RS07635
uniprot id: I9KU70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

880478:THESIDRAFT1 RS09420
gene id: 880478:THESIDRAFT1_RS09420
uniprot id: I8R081
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS00370
gene id: 880478:THESIDRAFT1_RS00370
uniprot id: I9KQG7
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS05925
gene id: 880478:THESIDRAFT1_RS05925
uniprot id: I8R451
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

880478:THESIDRAFT1 RS08555
gene id: 880478:THESIDRAFT1_RS08555
uniprot id: I9KUM2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

880478:THESIDRAFT1 RS11040
gene id: 880478:THESIDRAFT1_RS11040
uniprot id: I8R6F0
names: Similarity
messages: Belongs to the peptidase S14 family.

880478:THESIDRAFT1 RS11280
gene id: 880478:THESIDRAFT1_RS11280
uniprot id: I9AGP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

880478:THESIDRAFT1 RS07665
gene id: 880478:THESIDRAFT1_RS07665
uniprot id: I8R525
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

880478:THESIDRAFT1 RS01135
gene id: 880478:THESIDRAFT1_RS01135
uniprot id: I9AB87
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

880478:THESIDRAFT1 RS00200
gene id: 880478:THESIDRAFT1_RS00200
uniprot id: I9KQN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

880478:THESIDRAFT1 RS10650
gene id: 880478:THESIDRAFT1_RS10650
uniprot id: I9AGC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

880478:THESIDRAFT1 RS02400
gene id: 880478:THESIDRAFT1_RS02400
uniprot id: I9KRJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS12250
gene id: 880478:THESIDRAFT1_RS12250
uniprot id: I8R1T1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS10575
gene id: 880478:THESIDRAFT1_RS10575
uniprot id: I9AGB1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

880478:THESIDRAFT1 RS00165
gene id: 880478:THESIDRAFT1_RS00165
uniprot id: I8R155
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

880478:THESIDRAFT1 RS02090
gene id: 880478:THESIDRAFT1_RS02090
uniprot id: I9KRQ0
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

880478:THESIDRAFT1 RS07780
gene id: 880478:THESIDRAFT1_RS07780
uniprot id: I9KUK0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

880478:THESIDRAFT1 RS04815
gene id: 880478:THESIDRAFT1_RS04815
uniprot id: I8R3M4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

880478:THESIDRAFT1 RS04065
gene id: 880478:THESIDRAFT1_RS04065
uniprot id: I8QXU2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

880478:THESIDRAFT1 RS05920
gene id: 880478:THESIDRAFT1_RS05920
uniprot id: I9KTC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

880478:THESIDRAFT1 RS00745
gene id: 880478:THESIDRAFT1_RS00745
uniprot id: I8R1F5
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS06660
gene id: 880478:THESIDRAFT1_RS06660
uniprot id: I9AE75
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

880478:THESIDRAFT1 RS01815
gene id: 880478:THESIDRAFT1_RS01815
uniprot id: I8R214
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS03285
gene id: 880478:THESIDRAFT1_RS03285
uniprot id: I9KS99
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

880478:THESIDRAFT1 RS01965
gene id: 880478:THESIDRAFT1_RS01965
uniprot id: I9KRM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

880478:THESIDRAFT1 RS12480
gene id: 880478:THESIDRAFT1_RS12480
uniprot id: I9AHG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

880478:THESIDRAFT1 RS00355
gene id: 880478:THESIDRAFT1_RS00355
uniprot id: I8R185
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

880478:THESIDRAFT1 RS08855
gene id: 880478:THESIDRAFT1_RS08855
uniprot id: I9AFD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

880478:THESIDRAFT1 RS03990
gene id: 880478:THESIDRAFT1_RS03990
uniprot id: I8QXS6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

880478:THESIDRAFT1 RS10270
gene id: 880478:THESIDRAFT1_RS10270
uniprot id: I8R0P7
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

880478:THESIDRAFT1 RS08870
gene id: 880478:THESIDRAFT1_RS08870
uniprot id: I8R5J3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

880478:THESIDRAFT1 RS01565
gene id: 880478:THESIDRAFT1_RS01565
uniprot id: I9ABH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

880478:THESIDRAFT1 RS10820
gene id: 880478:THESIDRAFT1_RS10820
uniprot id: I9KW36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

880478:THESIDRAFT1 RS02770
gene id: 880478:THESIDRAFT1_RS02770
uniprot id: I8QXB7
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS05485
gene id: 880478:THESIDRAFT1_RS05485
uniprot id: I9KTF3
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

880478:THESIDRAFT1 RS05210
gene id: 880478:THESIDRAFT1_RS05210
uniprot id: I9KTA1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

880478:THESIDRAFT1 RS00950
gene id: 880478:THESIDRAFT1_RS00950
uniprot id: I9KR22
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

880478:THESIDRAFT1 RS00450
gene id: 880478:THESIDRAFT1_RS00450
uniprot id: I8R1A5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS10045
gene id: 880478:THESIDRAFT1_RS10045
uniprot id: I9KVD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

880478:THESIDRAFT1 RS01015
gene id: 880478:THESIDRAFT1_RS01015
uniprot id: I9KQT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS02640
gene id: 880478:THESIDRAFT1_RS02640
uniprot id: I9AC17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

880478:THESIDRAFT1 RS03055
gene id: 880478:THESIDRAFT1_RS03055
uniprot id: I8R2N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

880478:THESIDRAFT1 RS10600
gene id: 880478:THESIDRAFT1_RS10600
uniprot id: I9AGB3
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

880478:THESIDRAFT1 RS07185
gene id: 880478:THESIDRAFT1_RS07185
uniprot id: I8R4W2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

880478:THESIDRAFT1 RS05380
gene id: 880478:THESIDRAFT1_RS05380
uniprot id: I8R3V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

880478:THESIDRAFT1 RS00195
gene id: 880478:THESIDRAFT1_RS00195
uniprot id: I8R160
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

880478:THESIDRAFT1 RS03530
gene id: 880478:THESIDRAFT1_RS03530
uniprot id: I9KSD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

880478:THESIDRAFT1 RS08260
gene id: 880478:THESIDRAFT1_RS08260
uniprot id: I8QZN2
names: Similarity
messages: Belongs to the ThiD family.

880478:THESIDRAFT1 RS02445
gene id: 880478:THESIDRAFT1_RS02445
uniprot id: I8QX65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

880478:THESIDRAFT1 RS08010
gene id: 880478:THESIDRAFT1_RS08010
uniprot id: I8QZL2
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS06510
gene id: 880478:THESIDRAFT1_RS06510
uniprot id: I9KTV5
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

880478:THESIDRAFT1 RS12585
gene id: 880478:THESIDRAFT1_RS12585
uniprot id: I9KX00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

880478:THESIDRAFT1 RS05235
gene id: 880478:THESIDRAFT1_RS05235
uniprot id: I9KTA7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS02740
gene id: 880478:THESIDRAFT1_RS02740
uniprot id: I9AC33
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

880478:THESIDRAFT1 RS12530
gene id: 880478:THESIDRAFT1_RS12530
uniprot id: I9AHG5
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS07265
gene id: 880478:THESIDRAFT1_RS07265
uniprot id: I9KUC2
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

880478:THESIDRAFT1 RS00900
gene id: 880478:THESIDRAFT1_RS00900
uniprot id: I9AB38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

880478:THESIDRAFT1 RS11115
gene id: 880478:THESIDRAFT1_RS11115
uniprot id: I8R6G1
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

880478:THESIDRAFT1 RS09245
gene id: 880478:THESIDRAFT1_RS09245
uniprot id: I9AFL4
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

880478:THESIDRAFT1 RS09175
gene id: 880478:THESIDRAFT1_RS09175
uniprot id: I8R035
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS07900
gene id: 880478:THESIDRAFT1_RS07900
uniprot id: I9KUM0
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

880478:THESIDRAFT1 RS00560
gene id: 880478:THESIDRAFT1_RS00560
uniprot id: I9AAX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS03050
gene id: 880478:THESIDRAFT1_RS03050
uniprot id: I9KRW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

880478:THESIDRAFT1 RS07245
gene id: 880478:THESIDRAFT1_RS07245
uniprot id: I9AEL0
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

880478:THESIDRAFT1 RS09715
gene id: 880478:THESIDRAFT1_RS09715
uniprot id: I9AFY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

880478:THESIDRAFT1 RS08265
gene id: 880478:THESIDRAFT1_RS08265
uniprot id: I9KUH3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

880478:THESIDRAFT1 RS06235
gene id: 880478:THESIDRAFT1_RS06235
uniprot id: I9KTH6
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS10785
gene id: 880478:THESIDRAFT1_RS10785
uniprot id: I9KVP9
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

880478:THESIDRAFT1 RS09165
gene id: 880478:THESIDRAFT1_RS09165
uniprot id: I9KV69
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

880478:THESIDRAFT1 RS03160
gene id: 880478:THESIDRAFT1_RS03160
uniprot id: I9KS73
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

880478:THESIDRAFT1 RS01150
gene id: 880478:THESIDRAFT1_RS01150
uniprot id: I8R1M4
names: Similarity
messages: Belongs to the Tlp family.

880478:THESIDRAFT1 RS02520
gene id: 880478:THESIDRAFT1_RS02520
uniprot id: I8QX79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS12635
gene id: 880478:THESIDRAFT1_RS12635
uniprot id: I9KX09
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

880478:THESIDRAFT1 RS03640
gene id: 880478:THESIDRAFT1_RS03640
uniprot id: I8QXM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

880478:THESIDRAFT1 RS06150
gene id: 880478:THESIDRAFT1_RS06150
uniprot id: I9KTG3
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

880478:THESIDRAFT1 RS03720
gene id: 880478:THESIDRAFT1_RS03720
uniprot id: I9KS71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

880478:THESIDRAFT1 RS08635
gene id: 880478:THESIDRAFT1_RS08635
uniprot id: I8R5F8
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

880478:THESIDRAFT1 RS00050
gene id: 880478:THESIDRAFT1_RS00050
uniprot id: I8QVZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

880478:THESIDRAFT1 RS10030
gene id: 880478:THESIDRAFT1_RS10030
uniprot id: I9KVP7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.

880478:THESIDRAFT1 RS03200
gene id: 880478:THESIDRAFT1_RS03200
uniprot id: I9KRY8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS02130
gene id: 880478:THESIDRAFT1_RS02130
uniprot id: I9KRG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Cell membrane

880478:THESIDRAFT1 RS09720
gene id: 880478:THESIDRAFT1_RS09720
uniprot id: I8R0G4
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

880478:THESIDRAFT1 RS08970
gene id: 880478:THESIDRAFT1_RS08970
uniprot id: I8QZZ6
names: Similarity
messages: Belongs to the UDPGP type 2 family.

880478:THESIDRAFT1 RS10635
gene id: 880478:THESIDRAFT1_RS10635
uniprot id: I9KVM0
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

880478:THESIDRAFT1 RS09635
gene id: 880478:THESIDRAFT1_RS09635
uniprot id: I9KVF2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

880478:THESIDRAFT1 RS09885
gene id: 880478:THESIDRAFT1_RS09885
uniprot id: I9KVC3
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

880478:THESIDRAFT1 RS06085
gene id: 880478:THESIDRAFT1_RS06085
uniprot id: I9KTP2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

880478:THESIDRAFT1 RS03995
gene id: 880478:THESIDRAFT1_RS03995
uniprot id: I9KSC6
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

880478:THESIDRAFT1 RS03580
gene id: 880478:THESIDRAFT1_RS03580
uniprot id: I9KSE9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

880478:THESIDRAFT1 RS08315
gene id: 880478:THESIDRAFT1_RS08315
uniprot id: I8QZP0
names: Similarity
messages: Belongs to the leucine-binding protein family.

880478:THESIDRAFT1 RS02230
gene id: 880478:THESIDRAFT1_RS02230
uniprot id: I8R290
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

880478:THESIDRAFT1 RS03985
gene id: 880478:THESIDRAFT1_RS03985
uniprot id: I9ACT0
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

880478:THESIDRAFT1 RS07035
gene id: 880478:THESIDRAFT1_RS07035
uniprot id: I9KTX4
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

880478:THESIDRAFT1 RS07335
gene id: 880478:THESIDRAFT1_RS07335
uniprot id: I8QZC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

880478:THESIDRAFT1 RS00890
gene id: 880478:THESIDRAFT1_RS00890
uniprot id: I8R1H6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

880478:THESIDRAFT1 RS03570
gene id: 880478:THESIDRAFT1_RS03570
uniprot id: I9KS39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

880478:THESIDRAFT1 RS09835
gene id: 880478:THESIDRAFT1_RS09835
uniprot id: I8R5Z6
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS07415
gene id: 880478:THESIDRAFT1_RS07415
uniprot id: I9KUE3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

880478:THESIDRAFT1 RS02750
gene id: 880478:THESIDRAFT1_RS02750
uniprot id: I9KRQ9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

880478:THESIDRAFT1 RS12070
gene id: 880478:THESIDRAFT1_RS12070
uniprot id: I9KWQ5
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS03535
gene id: 880478:THESIDRAFT1_RS03535
uniprot id: I9ACI7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS04035
gene id: 880478:THESIDRAFT1_RS04035
uniprot id: I9ACU0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

880478:THESIDRAFT1 RS02285
gene id: 880478:THESIDRAFT1_RS02285
uniprot id: I9KRT1
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

880478:THESIDRAFT1 RS06320
gene id: 880478:THESIDRAFT1_RS06320
uniprot id: I8QYS2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

880478:THESIDRAFT1 RS11060
gene id: 880478:THESIDRAFT1_RS11060
uniprot id: I9KVV0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

880478:THESIDRAFT1 RS03920
gene id: 880478:THESIDRAFT1_RS03920
uniprot id: I8QXR5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

880478:THESIDRAFT1 RS06115
gene id: 880478:THESIDRAFT1_RS06115
uniprot id: I9ADY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

880478:THESIDRAFT1 RS02900
gene id: 880478:THESIDRAFT1_RS02900
uniprot id: I9KRT8
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

880478:THESIDRAFT1 RS09615
gene id: 880478:THESIDRAFT1_RS09615
uniprot id: I9AFT8
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

880478:THESIDRAFT1 RS07105
gene id: 880478:THESIDRAFT1_RS07105
uniprot id: I8R4U9
names: Function
names: Similarity
names: Subunit
messages: Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.
messages: Belongs to the HutP family.
messages: Homohexamer.

880478:THESIDRAFT1 RS09045
gene id: 880478:THESIDRAFT1_RS09045
uniprot id: I8R012
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS05780
gene id: 880478:THESIDRAFT1_RS05780
uniprot id: I8R426
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

880478:THESIDRAFT1 RS03585
gene id: 880478:THESIDRAFT1_RS03585
uniprot id: I9ACJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

880478:THESIDRAFT1 RS06110
gene id: 880478:THESIDRAFT1_RS06110
uniprot id: I9KTP6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

880478:THESIDRAFT1 RS12300
gene id: 880478:THESIDRAFT1_RS12300
uniprot id: I8R1V4
names: Similarity
messages: Belongs to the peptidase C56 family.

880478:THESIDRAFT1 RS09025
gene id: 880478:THESIDRAFT1_RS09025
uniprot id: I9KUV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Amj family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.

880478:THESIDRAFT1 RS09935
gene id: 880478:THESIDRAFT1_RS09935
uniprot id: I8R0K1
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

880478:THESIDRAFT1 RS11080
gene id: 880478:THESIDRAFT1_RS11080
uniprot id: I8R115
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

880478:THESIDRAFT1 RS07170
gene id: 880478:THESIDRAFT1_RS07170
uniprot id: I9AEK0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

880478:THESIDRAFT1 RS07930
gene id: 880478:THESIDRAFT1_RS07930
uniprot id: I9AEX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

880478:THESIDRAFT1 RS10145
gene id: 880478:THESIDRAFT1_RS10145
uniprot id: I8R0M9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

880478:THESIDRAFT1 RS09200
gene id: 880478:THESIDRAFT1_RS09200
uniprot id: I8R039
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS01985
gene id: 880478:THESIDRAFT1_RS01985
uniprot id: I8R251
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS03235
gene id: 880478:THESIDRAFT1_RS03235
uniprot id: I9KS89
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

880478:THESIDRAFT1 RS01645
gene id: 880478:THESIDRAFT1_RS01645
uniprot id: I9KR57
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS07190
gene id: 880478:THESIDRAFT1_RS07190
uniprot id: I9KUA9
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

880478:THESIDRAFT1 RS03880
gene id: 880478:THESIDRAFT1_RS03880
uniprot id: I8R330
names: Activity Regulation
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.

880478:THESIDRAFT1 RS09580
gene id: 880478:THESIDRAFT1_RS09580
uniprot id: I9KV58
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS03380
gene id: 880478:THESIDRAFT1_RS03380
uniprot id: I8R2U7
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

880478:THESIDRAFT1 RS00975
gene id: 880478:THESIDRAFT1_RS00975
uniprot id: I9KR25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

880478:THESIDRAFT1 RS11890
gene id: 880478:THESIDRAFT1_RS11890
uniprot id: I8R1I3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

880478:THESIDRAFT1 RS11550
gene id: 880478:THESIDRAFT1_RS11550
uniprot id: I9KW48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

880478:THESIDRAFT1 RS08385
gene id: 880478:THESIDRAFT1_RS08385
uniprot id: I9KUU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

880478:THESIDRAFT1 RS07670
gene id: 880478:THESIDRAFT1_RS07670
uniprot id: I9KUI0
names: Similarity
messages: Belongs to the MotB family.

880478:THESIDRAFT1 RS03335
gene id: 880478:THESIDRAFT1_RS03335
uniprot id: I9KSA8
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

880478:THESIDRAFT1 RS02815
gene id: 880478:THESIDRAFT1_RS02815
uniprot id: I9AC48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

880478:THESIDRAFT1 RS03690
gene id: 880478:THESIDRAFT1_RS03690
uniprot id: I8QXN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

880478:THESIDRAFT1 RS02835
gene id: 880478:THESIDRAFT1_RS02835
uniprot id: I9AC53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

880478:THESIDRAFT1 RS05770
gene id: 880478:THESIDRAFT1_RS05770
uniprot id: I8QYK4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

880478:THESIDRAFT1 RS06555
gene id: 880478:THESIDRAFT1_RS06555
uniprot id: I9KQR5
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

880478:THESIDRAFT1 RS04920
gene id: 880478:THESIDRAFT1_RS04920
uniprot id: I9KT54
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

880478:THESIDRAFT1 RS10800
gene id: 880478:THESIDRAFT1_RS10800
uniprot id: I9AGE8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

880478:THESIDRAFT1 RS07685
gene id: 880478:THESIDRAFT1_RS07685
uniprot id: I9KU78
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

880478:THESIDRAFT1 RS11640
gene id: 880478:THESIDRAFT1_RS11640
uniprot id: I9AGX2
names: Similarity
messages: Belongs to the GSP E family.

880478:THESIDRAFT1 RS03645
gene id: 880478:THESIDRAFT1_RS03645
uniprot id: I9KS56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

880478:THESIDRAFT1 RS11460
gene id: 880478:THESIDRAFT1_RS11460
uniprot id: I9KWF7
names: Similarity
messages: Belongs to the TlyA family.

880478:THESIDRAFT1 RS05595
gene id: 880478:THESIDRAFT1_RS05595
uniprot id: I8QYI6
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

880478:THESIDRAFT1 RS06580
gene id: 880478:THESIDRAFT1_RS06580
uniprot id: I9KTW6
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

880478:THESIDRAFT1 RS11825
gene id: 880478:THESIDRAFT1_RS11825
uniprot id: I9KWA1
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS04105
gene id: 880478:THESIDRAFT1_RS04105
uniprot id: I9KSP2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

880478:THESIDRAFT1 RS00245
gene id: 880478:THESIDRAFT1_RS00245
uniprot id: I8R168
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

880478:THESIDRAFT1 RS02650
gene id: 880478:THESIDRAFT1_RS02650
uniprot id: I9KRP2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

880478:THESIDRAFT1 RS10425
gene id: 880478:THESIDRAFT1_RS10425
uniprot id: I9AG83
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

880478:THESIDRAFT1 RS11950
gene id: 880478:THESIDRAFT1_RS11950
uniprot id: I8R6V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS03320
gene id: 880478:THESIDRAFT1_RS03320
uniprot id: I8QXJ4
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

880478:THESIDRAFT1 RS03710
gene id: 880478:THESIDRAFT1_RS03710
uniprot id: I9ACM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

880478:THESIDRAFT1 RS09570
gene id: 880478:THESIDRAFT1_RS09570
uniprot id: I9AFS9
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS08395
gene id: 880478:THESIDRAFT1_RS08395
uniprot id: I8QZQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

880478:THESIDRAFT1 RS06945
gene id: 880478:THESIDRAFT1_RS06945
uniprot id: I8QZ37
names: Similarity
names: Subunit
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

880478:THESIDRAFT1 RS03810
gene id: 880478:THESIDRAFT1_RS03810
uniprot id: I9ACP4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

880478:THESIDRAFT1 RS11910
gene id: 880478:THESIDRAFT1_RS11910
uniprot id: I9AH30
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

880478:THESIDRAFT1 RS00250
gene id: 880478:THESIDRAFT1_RS00250
uniprot id: I9KQP0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

880478:THESIDRAFT1 RS01625
gene id: 880478:THESIDRAFT1_RS01625
uniprot id: I9KR52
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS06290
gene id: 880478:THESIDRAFT1_RS06290
uniprot id: I9KTI6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

880478:THESIDRAFT1 RS09860
gene id: 880478:THESIDRAFT1_RS09860
uniprot id: I9KVB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

880478:THESIDRAFT1 RS07675
gene id: 880478:THESIDRAFT1_RS07675
uniprot id: I9AER9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

880478:THESIDRAFT1 RS05725
gene id: 880478:THESIDRAFT1_RS05725
uniprot id: I8R415
names: Cofactor
messages: Binds 1 zinc ion per subunit.

880478:THESIDRAFT1 RS05515
gene id: 880478:THESIDRAFT1_RS05515
uniprot id: I9ADL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

880478:THESIDRAFT1 RS01005
gene id: 880478:THESIDRAFT1_RS01005
uniprot id: I9AB61
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

880478:THESIDRAFT1 RS05525
gene id: 880478:THESIDRAFT1_RS05525
uniprot id: I9KT51
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

880478:THESIDRAFT1 RS00405
gene id: 880478:THESIDRAFT1_RS00405
uniprot id: I9KQR9
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

880478:THESIDRAFT1 RS02995
gene id: 880478:THESIDRAFT1_RS02995
uniprot id: I9AC84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

880478:THESIDRAFT1 RS06860
gene id: 880478:THESIDRAFT1_RS06860
uniprot id: I9KU19
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS00420
gene id: 880478:THESIDRAFT1_RS00420
uniprot id: I9KQH7
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS12565
gene id: 880478:THESIDRAFT1_RS12565
uniprot id: I9KWQ6
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

880478:THESIDRAFT1 RS07710
gene id: 880478:THESIDRAFT1_RS07710
uniprot id: I8R534
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

880478:THESIDRAFT1 RS01560
gene id: 880478:THESIDRAFT1_RS01560
uniprot id: I9KRC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

880478:THESIDRAFT1 RS06790
gene id: 880478:THESIDRAFT1_RS06790
uniprot id: I8QZ03
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

880478:THESIDRAFT1 RS09215
gene id: 880478:THESIDRAFT1_RS09215
uniprot id: I9KV78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S8 family.
messages: Monomer.
messages: Serine protease with a broad substrate specificity.

880478:THESIDRAFT1 RS03865
gene id: 880478:THESIDRAFT1_RS03865
uniprot id: I9ACQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

880478:THESIDRAFT1 RS02060
gene id: 880478:THESIDRAFT1_RS02060
uniprot id: I8R264
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

880478:THESIDRAFT1 RS12225
gene id: 880478:THESIDRAFT1_RS12225
uniprot id: I9AH91
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

880478:THESIDRAFT1 RS07275
gene id: 880478:THESIDRAFT1_RS07275
uniprot id: I8QZC4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

880478:THESIDRAFT1 RS08880
gene id: 880478:THESIDRAFT1_RS08880
uniprot id: I9AFE2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

880478:THESIDRAFT1 RS12465
gene id: 880478:THESIDRAFT1_RS12465
uniprot id: I9KWP2
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

880478:THESIDRAFT1 RS01175
gene id: 880478:THESIDRAFT1_RS01175
uniprot id: I8R1M9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS08980
gene id: 880478:THESIDRAFT1_RS08980
uniprot id: I8R5L0
names: Similarity
messages: Belongs to the CpsD/CapB family.

880478:THESIDRAFT1 RS11715
gene id: 880478:THESIDRAFT1_RS11715
uniprot id: I9AGY7
names: Similarity
messages: Belongs to the UPF0297 family.

880478:THESIDRAFT1 RS11110
gene id: 880478:THESIDRAFT1_RS11110
uniprot id: I9KVW2
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

880478:THESIDRAFT1 RS09090
gene id: 880478:THESIDRAFT1_RS09090
uniprot id: I9AFI4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

880478:THESIDRAFT1 RS01075
gene id: 880478:THESIDRAFT1_RS01075
uniprot id: I8R1K8
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

880478:THESIDRAFT1 RS01540
gene id: 880478:THESIDRAFT1_RS01540
uniprot id: I8R1U0
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this 1-Cys peroxiredoxin, no C(R) is present and C(P) instead forms a disulfide with a cysteine from another protein or with a small thiol molecule.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

880478:THESIDRAFT1 RS10940
gene id: 880478:THESIDRAFT1_RS10940
uniprot id: I8R6D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

880478:THESIDRAFT1 RS00115
gene id: 880478:THESIDRAFT1_RS00115
uniprot id: I9KQL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

880478:THESIDRAFT1 RS06165
gene id: 880478:THESIDRAFT1_RS06165
uniprot id: I8QYQ0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS10290
gene id: 880478:THESIDRAFT1_RS10290
uniprot id: I9AG66
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

880478:THESIDRAFT1 RS04325
gene id: 880478:THESIDRAFT1_RS04325
uniprot id: I9ACZ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 66 family.

880478:THESIDRAFT1 RS12385
gene id: 880478:THESIDRAFT1_RS12385
uniprot id: I9KWN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

880478:THESIDRAFT1 RS08960
gene id: 880478:THESIDRAFT1_RS08960
uniprot id: I9KV35
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

880478:THESIDRAFT1 RS13470
gene id: 880478:THESIDRAFT1_RS13470
uniprot id: I9KRN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS03765
gene id: 880478:THESIDRAFT1_RS03765
uniprot id: I8QXP3
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

880478:THESIDRAFT1 RS10840
gene id: 880478:THESIDRAFT1_RS10840
uniprot id: I8R6C2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

880478:THESIDRAFT1 RS03970
gene id: 880478:THESIDRAFT1_RS03970
uniprot id: I9KSC1
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

880478:THESIDRAFT1 RS06035
gene id: 880478:THESIDRAFT1_RS06035
uniprot id: I9KTN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

880478:THESIDRAFT1 RS06730
gene id: 880478:THESIDRAFT1_RS06730
uniprot id: I9KTZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Membrane

880478:THESIDRAFT1 RS01130
gene id: 880478:THESIDRAFT1_RS01130
uniprot id: I9KR54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YdjC deacetylase family.
messages: Homodimer.
messages: Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides.

880478:THESIDRAFT1 RS10040
gene id: 880478:THESIDRAFT1_RS10040
uniprot id: I8R0L5
names: Similarity
messages: Belongs to the UPF0045 family.

880478:THESIDRAFT1 RS02435
gene id: 880478:THESIDRAFT1_RS02435
uniprot id: I9KRV4
names: Similarity
messages: Belongs to the transpeptidase family.

880478:THESIDRAFT1 RS11490
gene id: 880478:THESIDRAFT1_RS11490
uniprot id: I9AGT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

880478:THESIDRAFT1 RS11020
gene id: 880478:THESIDRAFT1_RS11020
uniprot id: I9KW75
names: Similarity
messages: Belongs to the peptidase M16 family.

880478:THESIDRAFT1 RS10285
gene id: 880478:THESIDRAFT1_RS10285
uniprot id: I9KVU3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

880478:THESIDRAFT1 RS09285
gene id: 880478:THESIDRAFT1_RS09285
uniprot id: I8R5Q6
names: Similarity
messages: Belongs to the glutamine synthetase family.

880478:THESIDRAFT1 RS06215
gene id: 880478:THESIDRAFT1_RS06215
uniprot id: I8R4A3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS00415
gene id: 880478:THESIDRAFT1_RS00415
uniprot id: I8QW49
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS05120
gene id: 880478:THESIDRAFT1_RS05120
uniprot id: I9KSX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.
messages: Membrane

880478:THESIDRAFT1 RS05285
gene id: 880478:THESIDRAFT1_RS05285
uniprot id: I9KTB6
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

880478:THESIDRAFT1 RS04025
gene id: 880478:THESIDRAFT1_RS04025
uniprot id: I8R358
names: Similarity
messages: Belongs to the GerABKA family.

880478:THESIDRAFT1 RS05530
gene id: 880478:THESIDRAFT1_RS05530
uniprot id: I8R3X5
names: Similarity
messages: Belongs to the UPF0735 family.

880478:THESIDRAFT1 RS11635
gene id: 880478:THESIDRAFT1_RS11635
uniprot id: I9KWI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS01170
gene id: 880478:THESIDRAFT1_RS01170
uniprot id: I9KQW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

880478:THESIDRAFT1 RS11560
gene id: 880478:THESIDRAFT1_RS11560
uniprot id: I9KWH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

880478:THESIDRAFT1 RS09485
gene id: 880478:THESIDRAFT1_RS09485
uniprot id: I8R5U0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

880478:THESIDRAFT1 RS11675
gene id: 880478:THESIDRAFT1_RS11675
uniprot id: I9KW71
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS00840
gene id: 880478:THESIDRAFT1_RS00840
uniprot id: I8R1G8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

880478:THESIDRAFT1 RS02125
gene id: 880478:THESIDRAFT1_RS02125
uniprot id: I8QX13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

880478:THESIDRAFT1 RS09630
gene id: 880478:THESIDRAFT1_RS09630
uniprot id: I8R5W5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

880478:THESIDRAFT1 RS10915
gene id: 880478:THESIDRAFT1_RS10915
uniprot id: I8R6D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

880478:THESIDRAFT1 RS11410
gene id: 880478:THESIDRAFT1_RS11410
uniprot id: I9KWE8
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS03165
gene id: 880478:THESIDRAFT1_RS03165
uniprot id: I9ACC1
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

880478:THESIDRAFT1 RS06830
gene id: 880478:THESIDRAFT1_RS06830
uniprot id: I9KU14
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS01435
gene id: 880478:THESIDRAFT1_RS01435
uniprot id: I9KR10
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

880478:THESIDRAFT1 RS09535
gene id: 880478:THESIDRAFT1_RS09535
uniprot id: I8R5U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

880478:THESIDRAFT1 RS03615
gene id: 880478:THESIDRAFT1_RS03615
uniprot id: I8QXM1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

880478:THESIDRAFT1 RS03820
gene id: 880478:THESIDRAFT1_RS03820
uniprot id: I9KS91
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

880478:THESIDRAFT1 RS09710
gene id: 880478:THESIDRAFT1_RS09710
uniprot id: I9KVI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

880478:THESIDRAFT1 RS06520
gene id: 880478:THESIDRAFT1_RS06520
uniprot id: I8QYU9
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

880478:THESIDRAFT1 RS05375
gene id: 880478:THESIDRAFT1_RS05375
uniprot id: I9KT23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

880478:THESIDRAFT1 RS07990
gene id: 880478:THESIDRAFT1_RS07990
uniprot id: I9KUD2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

880478:THESIDRAFT1 RS04965
gene id: 880478:THESIDRAFT1_RS04965
uniprot id: I9KSV3
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS09645
gene id: 880478:THESIDRAFT1_RS09645
uniprot id: I8R0C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

880478:THESIDRAFT1 RS08410
gene id: 880478:THESIDRAFT1_RS08410
uniprot id: I9KUU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS09930
gene id: 880478:THESIDRAFT1_RS09930
uniprot id: I9AG10
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

880478:THESIDRAFT1 RS05545
gene id: 880478:THESIDRAFT1_RS05545
uniprot id: I8QYH9
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

880478:THESIDRAFT1 RS05395
gene id: 880478:THESIDRAFT1_RS05395
uniprot id: I8QYF7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

880478:THESIDRAFT1 RS10010
gene id: 880478:THESIDRAFT1_RS10010
uniprot id: I9AG23
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

880478:THESIDRAFT1 RS05535
gene id: 880478:THESIDRAFT1_RS05535
uniprot id: I9KTG1
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS08465
gene id: 880478:THESIDRAFT1_RS08465
uniprot id: I9KUV4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

880478:THESIDRAFT1 RS01085
gene id: 880478:THESIDRAFT1_RS01085
uniprot id: I9AB80
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

880478:THESIDRAFT1 RS11690
gene id: 880478:THESIDRAFT1_RS11690
uniprot id: I9AGY2
names: Similarity
messages: Belongs to the UPF0342 family.

880478:THESIDRAFT1 RS01405
gene id: 880478:THESIDRAFT1_RS01405
uniprot id: I8QWJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

880478:THESIDRAFT1 RS10880
gene id: 880478:THESIDRAFT1_RS10880
uniprot id: I8R0Y3
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

880478:THESIDRAFT1 RS09185
gene id: 880478:THESIDRAFT1_RS09185
uniprot id: I8R5P1
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

880478:THESIDRAFT1 RS08730
gene id: 880478:THESIDRAFT1_RS08730
uniprot id: I9KUQ3
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

880478:THESIDRAFT1 RS11175
gene id: 880478:THESIDRAFT1_RS11175
uniprot id: I9KW99
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

880478:THESIDRAFT1 RS11500
gene id: 880478:THESIDRAFT1_RS11500
uniprot id: I9KW39
names: Similarity
messages: Belongs to the asp23 family.

880478:THESIDRAFT1 RS04130
gene id: 880478:THESIDRAFT1_RS04130
uniprot id: I8R376
names: Similarity
messages: Belongs to the EamA transporter family.

880478:THESIDRAFT1 RS04060
gene id: 880478:THESIDRAFT1_RS04060
uniprot id: I9ACU5
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

880478:THESIDRAFT1 RS03650
gene id: 880478:THESIDRAFT1_RS03650
uniprot id: I8R2Y7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

880478:THESIDRAFT1 RS09195
gene id: 880478:THESIDRAFT1_RS09195
uniprot id: I9AFK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS09355
gene id: 880478:THESIDRAFT1_RS09355
uniprot id: I9KV20
names: Similarity
messages: Belongs to the peptidase S49 family.

880478:THESIDRAFT1 RS03685
gene id: 880478:THESIDRAFT1_RS03685
uniprot id: I9ACL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

880478:THESIDRAFT1 RS03595
gene id: 880478:THESIDRAFT1_RS03595
uniprot id: I9KS44
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

880478:THESIDRAFT1 RS01195
gene id: 880478:THESIDRAFT1_RS01195
uniprot id: I9KQW8
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS02480
gene id: 880478:THESIDRAFT1_RS02480
uniprot id: I8R2C6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

880478:THESIDRAFT1 RS05180
gene id: 880478:THESIDRAFT1_RS05180
uniprot id: I8R3S5
names: Similarity
messages: Belongs to the peptidase C40 family.

880478:THESIDRAFT1 RS06535
gene id: 880478:THESIDRAFT1_RS06535
uniprot id: I9KTW0
names: Similarity
messages: Belongs to the DsrF/TusC family.

880478:THESIDRAFT1 RS10815
gene id: 880478:THESIDRAFT1_RS10815
uniprot id: I8R6B7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

880478:THESIDRAFT1 RS07305
gene id: 880478:THESIDRAFT1_RS07305
uniprot id: I9KU28
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

880478:THESIDRAFT1 RS01335
gene id: 880478:THESIDRAFT1_RS01335
uniprot id: I9KQZ0
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

880478:THESIDRAFT1 RS03310
gene id: 880478:THESIDRAFT1_RS03310
uniprot id: I9KSA4
names: Similarity
messages: Belongs to the EamA transporter family.

880478:THESIDRAFT1 RS10690
gene id: 880478:THESIDRAFT1_RS10690
uniprot id: I8R6A0
names: Similarity
messages: Belongs to the UPF0102 family.

880478:THESIDRAFT1 RS06415
gene id: 880478:THESIDRAFT1_RS06415
uniprot id: I9AE30
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

880478:THESIDRAFT1 RS10220
gene id: 880478:THESIDRAFT1_RS10220
uniprot id: I8R0N9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

880478:THESIDRAFT1 RS08770
gene id: 880478:THESIDRAFT1_RS08770
uniprot id: I9AFC5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS10450
gene id: 880478:THESIDRAFT1_RS10450
uniprot id: I9AG88
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

880478:THESIDRAFT1 RS03065
gene id: 880478:THESIDRAFT1_RS03065
uniprot id: I9ACA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

880478:THESIDRAFT1 RS08025
gene id: 880478:THESIDRAFT1_RS08025
uniprot id: I9KUP2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

880478:THESIDRAFT1 RS01945
gene id: 880478:THESIDRAFT1_RS01945
uniprot id: I9ABQ4
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.

880478:THESIDRAFT1 RS11010
gene id: 880478:THESIDRAFT1_RS11010
uniprot id: I9KVU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

880478:THESIDRAFT1 RS12430
gene id: 880478:THESIDRAFT1_RS12430
uniprot id: I8R1X9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

880478:THESIDRAFT1 RS05955
gene id: 880478:THESIDRAFT1_RS05955
uniprot id: I9KTM3
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

880478:THESIDRAFT1 RS09560
gene id: 880478:THESIDRAFT1_RS09560
uniprot id: I8R5V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS08340
gene id: 880478:THESIDRAFT1_RS08340
uniprot id: I9AF36
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

880478:THESIDRAFT1 RS03910
gene id: 880478:THESIDRAFT1_RS03910
uniprot id: I9KSK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

880478:THESIDRAFT1 RS05005
gene id: 880478:THESIDRAFT1_RS05005
uniprot id: I9ADC4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS05070
gene id: 880478:THESIDRAFT1_RS05070
uniprot id: I8R3R1
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS08380
gene id: 880478:THESIDRAFT1_RS08380
uniprot id: I8R5B6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

880478:THESIDRAFT1 RS05045
gene id: 880478:THESIDRAFT1_RS05045
uniprot id: I8R3Q8
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

880478:THESIDRAFT1 RS10825
gene id: 880478:THESIDRAFT1_RS10825
uniprot id: I9AGF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

880478:THESIDRAFT1 RS06100
gene id: 880478:THESIDRAFT1_RS06100
uniprot id: I9KTF4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS03045
gene id: 880478:THESIDRAFT1_RS03045
uniprot id: I8QXF4
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

880478:THESIDRAFT1 RS10025
gene id: 880478:THESIDRAFT1_RS10025
uniprot id: I8R619
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

880478:THESIDRAFT1 RS10605
gene id: 880478:THESIDRAFT1_RS10605
uniprot id: I8R0T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

880478:THESIDRAFT1 RS00395
gene id: 880478:THESIDRAFT1_RS00395
uniprot id: I9KQH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

880478:THESIDRAFT1 RS02565
gene id: 880478:THESIDRAFT1_RS02565
uniprot id: I9AC03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS03980
gene id: 880478:THESIDRAFT1_RS03980
uniprot id: I9KSM2
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

880478:THESIDRAFT1 RS05400
gene id: 880478:THESIDRAFT1_RS05400
uniprot id: I9KT27
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS05215
gene id: 880478:THESIDRAFT1_RS05215
uniprot id: I9ADG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS03315
gene id: 880478:THESIDRAFT1_RS03315
uniprot id: I9ACF1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

880478:THESIDRAFT1 RS12645
gene id: 880478:THESIDRAFT1_RS12645
uniprot id: I8R208
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

880478:THESIDRAFT1 RS01455
gene id: 880478:THESIDRAFT1_RS01455
uniprot id: I8QWK1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

880478:THESIDRAFT1 RS06480
gene id: 880478:THESIDRAFT1_RS06480
uniprot id: I8R4E3
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

880478:THESIDRAFT1 RS03875
gene id: 880478:THESIDRAFT1_RS03875
uniprot id: I9KSA1
names: Similarity
messages: Belongs to the ClpA/ClpB family.

880478:THESIDRAFT1 RS07695
gene id: 880478:THESIDRAFT1_RS07695
uniprot id: I9KUI6
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

880478:THESIDRAFT1 RS02250
gene id: 880478:THESIDRAFT1_RS02250
uniprot id: I8R294
names: Function
names: Subcellular Location Annotation
messages: Chaperone that serves for the intracellular sequestration and transport of Cu(+). Delivers Cu(+) to the copper-exporting P-type ATPase A (CopA).
messages: Cytoplasm

880478:THESIDRAFT1 RS01020
gene id: 880478:THESIDRAFT1_RS01020
uniprot id: I8R1J8
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

880478:THESIDRAFT1 RS06400
gene id: 880478:THESIDRAFT1_RS06400
uniprot id: I9KTJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS10070
gene id: 880478:THESIDRAFT1_RS10070
uniprot id: I9KVE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

880478:THESIDRAFT1 RS08460
gene id: 880478:THESIDRAFT1_RS08460
uniprot id: I8R5C9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

880478:THESIDRAFT1 RS09105
gene id: 880478:THESIDRAFT1_RS09105
uniprot id: I8R5M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

880478:THESIDRAFT1 RS00430
gene id: 880478:THESIDRAFT1_RS00430
uniprot id: I9KQS3
names: Similarity
messages: Belongs to the BMP lipoprotein family.

880478:THESIDRAFT1 RS06800
gene id: 880478:THESIDRAFT1_RS06800
uniprot id: I8R4K3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS06095
gene id: 880478:THESIDRAFT1_RS06095
uniprot id: I8QYN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

880478:THESIDRAFT1 RS09965
gene id: 880478:THESIDRAFT1_RS09965
uniprot id: I9KVD0
names: Similarity
messages: Belongs to the RutC family.

880478:THESIDRAFT1 RS05865
gene id: 880478:THESIDRAFT1_RS05865
uniprot id: I9ADS8
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS12090
gene id: 880478:THESIDRAFT1_RS12090
uniprot id: I8R6Y1
names: Similarity
messages: Belongs to the creatininase superfamily.

880478:THESIDRAFT1 RS05040
gene id: 880478:THESIDRAFT1_RS05040
uniprot id: I9KSW4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

880478:THESIDRAFT1 RS05880
gene id: 880478:THESIDRAFT1_RS05880
uniprot id: I9KTL1
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

880478:THESIDRAFT1 RS12520
gene id: 880478:THESIDRAFT1_RS12520
uniprot id: I8R755
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

880478:THESIDRAFT1 RS09740
gene id: 880478:THESIDRAFT1_RS09740
uniprot id: I8R0H3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

880478:THESIDRAFT1 RS07555
gene id: 880478:THESIDRAFT1_RS07555
uniprot id: I8QZF1
names: Similarity
messages: Belongs to the peptidase M18 family.

880478:THESIDRAFT1 RS12175
gene id: 880478:THESIDRAFT1_RS12175
uniprot id: I9AH83
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS11335
gene id: 880478:THESIDRAFT1_RS11335
uniprot id: I8R6K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS00205
gene id: 880478:THESIDRAFT1_RS00205
uniprot id: I9AAQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

880478:THESIDRAFT1 RS10645
gene id: 880478:THESIDRAFT1_RS10645
uniprot id: I9KW00
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

880478:THESIDRAFT1 RS10465
gene id: 880478:THESIDRAFT1_RS10465
uniprot id: I8R674
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

880478:THESIDRAFT1 RS03675
gene id: 880478:THESIDRAFT1_RS03675
uniprot id: I8R2Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

880478:THESIDRAFT1 RS01045
gene id: 880478:THESIDRAFT1_RS01045
uniprot id: I8R1K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS09060
gene id: 880478:THESIDRAFT1_RS09060
uniprot id: I9KV51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

880478:THESIDRAFT1 RS08780
gene id: 880478:THESIDRAFT1_RS08780
uniprot id: I9KUR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

880478:THESIDRAFT1 RS07005
gene id: 880478:THESIDRAFT1_RS07005
uniprot id: I9KU45
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

880478:THESIDRAFT1 RS00315
gene id: 880478:THESIDRAFT1_RS00315
uniprot id: I9AAS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS03075
gene id: 880478:THESIDRAFT1_RS03075
uniprot id: I9KRW6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

880478:THESIDRAFT1 RS10255
gene id: 880478:THESIDRAFT1_RS10255
uniprot id: I8R651
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

880478:THESIDRAFT1 RS01385
gene id: 880478:THESIDRAFT1_RS01385
uniprot id: I9KR00
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

880478:THESIDRAFT1 RS02590
gene id: 880478:THESIDRAFT1_RS02590
uniprot id: I9AC07
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

880478:THESIDRAFT1 RS03000
gene id: 880478:THESIDRAFT1_RS03000
uniprot id: I8QXE8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

880478:THESIDRAFT1 RS00765
gene id: 880478:THESIDRAFT1_RS00765
uniprot id: I9KQY6
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

880478:THESIDRAFT1 RS06725
gene id: 880478:THESIDRAFT1_RS06725
uniprot id: I8R4I6
names: Similarity
messages: Belongs to the AAA ATPase family.
messages: In the C-terminal section; belongs to the peptidase M41 family.

880478:THESIDRAFT1 RS00865
gene id: 880478:THESIDRAFT1_RS00865
uniprot id: I8R1H2
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

880478:THESIDRAFT1 RS07600
gene id: 880478:THESIDRAFT1_RS07600
uniprot id: I8QZF9
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

880478:THESIDRAFT1 RS09410
gene id: 880478:THESIDRAFT1_RS09410
uniprot id: I9KVB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

880478:THESIDRAFT1 RS11340
gene id: 880478:THESIDRAFT1_RS11340
uniprot id: I9KWD4
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

880478:THESIDRAFT1 RS11615
gene id: 880478:THESIDRAFT1_RS11615
uniprot id: I9AGW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP I family.
messages: Membrane

880478:THESIDRAFT1 RS11935
gene id: 880478:THESIDRAFT1_RS11935
uniprot id: I9AH36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

880478:THESIDRAFT1 RS09475
gene id: 880478:THESIDRAFT1_RS09475
uniprot id: I8R092
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

880478:THESIDRAFT1 RS05675
gene id: 880478:THESIDRAFT1_RS05675
uniprot id: I8R405
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS09575
gene id: 880478:THESIDRAFT1_RS09575
uniprot id: I8R0B1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS06275
gene id: 880478:THESIDRAFT1_RS06275
uniprot id: I9KTS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

880478:THESIDRAFT1 RS06775
gene id: 880478:THESIDRAFT1_RS06775
uniprot id: I8R4J9
names: Similarity
messages: Belongs to the HupF/HypC family.

880478:THESIDRAFT1 RS03740
gene id: 880478:THESIDRAFT1_RS03740
uniprot id: I8QXP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

880478:THESIDRAFT1 RS12030
gene id: 880478:THESIDRAFT1_RS12030
uniprot id: I8R1K7
names: Similarity
messages: Belongs to the thioredoxin family.

880478:THESIDRAFT1 RS09600
gene id: 880478:THESIDRAFT1_RS09600
uniprot id: I8R0B8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

880478:THESIDRAFT1 RS00130
gene id: 880478:THESIDRAFT1_RS00130
uniprot id: I9KQC8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

880478:THESIDRAFT1 RS02810
gene id: 880478:THESIDRAFT1_RS02810
uniprot id: I9KS12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

880478:THESIDRAFT1 RS00880
gene id: 880478:THESIDRAFT1_RS00880
uniprot id: I8QWB4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

880478:THESIDRAFT1 RS12380
gene id: 880478:THESIDRAFT1_RS12380
uniprot id: I8R1W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

880478:THESIDRAFT1 RS12475
gene id: 880478:THESIDRAFT1_RS12475
uniprot id: I9KWY2
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

880478:THESIDRAFT1 RS10445
gene id: 880478:THESIDRAFT1_RS10445
uniprot id: I9KVW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

880478:THESIDRAFT1 RS10720
gene id: 880478:THESIDRAFT1_RS10720
uniprot id: I9KW15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.

880478:THESIDRAFT1 RS05630
gene id: 880478:THESIDRAFT1_RS05630
uniprot id: I8R3Z4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Heptamer of 7 subunits arranged in a ring.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

880478:THESIDRAFT1 RS05620
gene id: 880478:THESIDRAFT1_RS05620
uniprot id: I8QYI9
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

880478:THESIDRAFT1 RS10965
gene id: 880478:THESIDRAFT1_RS10965
uniprot id: I8R6D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

880478:THESIDRAFT1 RS10260
gene id: 880478:THESIDRAFT1_RS10260
uniprot id: I9KVT8
names: Similarity
messages: Belongs to the HypE family.

880478:THESIDRAFT1 RS06030
gene id: 880478:THESIDRAFT1_RS06030
uniprot id: I8R468
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

880478:THESIDRAFT1 RS05155
gene id: 880478:THESIDRAFT1_RS05155
uniprot id: I8R3S1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

880478:THESIDRAFT1 RS01400
gene id: 880478:THESIDRAFT1_RS01400
uniprot id: I9ABE0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

880478:THESIDRAFT1 RS05295
gene id: 880478:THESIDRAFT1_RS05295
uniprot id: I8QYE3
names: Similarity
messages: Belongs to the SleB family.

880478:THESIDRAFT1 RS10665
gene id: 880478:THESIDRAFT1_RS10665
uniprot id: I8R696
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

880478:THESIDRAFT1 RS10730
gene id: 880478:THESIDRAFT1_RS10730
uniprot id: I8R0V3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

880478:THESIDRAFT1 RS02665
gene id: 880478:THESIDRAFT1_RS02665
uniprot id: I9AC20
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

880478:THESIDRAFT1 RS08180
gene id: 880478:THESIDRAFT1_RS08180
uniprot id: I9AF06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS06935
gene id: 880478:THESIDRAFT1_RS06935
uniprot id: I9KU33
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS04095
gene id: 880478:THESIDRAFT1_RS04095
uniprot id: I9KSE5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

880478:THESIDRAFT1 RS10710
gene id: 880478:THESIDRAFT1_RS10710
uniprot id: I9KVN3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

880478:THESIDRAFT1 RS09425
gene id: 880478:THESIDRAFT1_RS09425
uniprot id: I9KV33
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

880478:THESIDRAFT1 RS02745
gene id: 880478:THESIDRAFT1_RS02745
uniprot id: I8QXB2
names: Cofactor
names: Similarity
messages: Belongs to the PHP family.
messages: Binds 3 Zn(2+) ions per subunit.

880478:THESIDRAFT1 RS02610
gene id: 880478:THESIDRAFT1_RS02610
uniprot id: I9KRX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS03850
gene id: 880478:THESIDRAFT1_RS03850
uniprot id: I8R324
names: Similarity
messages: Belongs to the ycf81 family.

880478:THESIDRAFT1 RS07825
gene id: 880478:THESIDRAFT1_RS07825
uniprot id: I9KUK7
names: Similarity
messages: Belongs to the peptidase S8 family.

880478:THESIDRAFT1 RS10725
gene id: 880478:THESIDRAFT1_RS10725
uniprot id: I9AGD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

880478:THESIDRAFT1 RS04430
gene id: 880478:THESIDRAFT1_RS04430
uniprot id: I9KSX6
names: Similarity
messages: Belongs to the UPF0236 family.

880478:THESIDRAFT1 RS05430
gene id: 880478:THESIDRAFT1_RS05430
uniprot id: I8R3W0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

880478:THESIDRAFT1 RS08990
gene id: 880478:THESIDRAFT1_RS08990
uniprot id: I9AFG2
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

880478:THESIDRAFT1 RS02385
gene id: 880478:THESIDRAFT1_RS02385
uniprot id: I9KRU8
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

880478:THESIDRAFT1 RS09035
gene id: 880478:THESIDRAFT1_RS09035
uniprot id: I9KQR5
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

880478:THESIDRAFT1 RS01350
gene id: 880478:THESIDRAFT1_RS01350
uniprot id: I9ABD0
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS06000
gene id: 880478:THESIDRAFT1_RS06000
uniprot id: I8R465
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

880478:THESIDRAFT1 RS10810
gene id: 880478:THESIDRAFT1_RS10810
uniprot id: I9KVQ3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

880478:THESIDRAFT1 RS10805
gene id: 880478:THESIDRAFT1_RS10805
uniprot id: I8R0X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

880478:THESIDRAFT1 RS11895
gene id: 880478:THESIDRAFT1_RS11895
uniprot id: I9KWB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

880478:THESIDRAFT1 RS01315
gene id: 880478:THESIDRAFT1_RS01315
uniprot id: I9KR88
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

880478:THESIDRAFT1 RS11430
gene id: 880478:THESIDRAFT1_RS11430
uniprot id: I8R6L7
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

880478:THESIDRAFT1 RS04150
gene id: 880478:THESIDRAFT1_RS04150
uniprot id: I9KSF4
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS04925
gene id: 880478:THESIDRAFT1_RS04925
uniprot id: I9ADB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

880478:THESIDRAFT1 RS01900
gene id: 880478:THESIDRAFT1_RS01900
uniprot id: I8QWX6
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

880478:THESIDRAFT1 RS08310
gene id: 880478:THESIDRAFT1_RS08310
uniprot id: I9AF32
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS05315
gene id: 880478:THESIDRAFT1_RS05315
uniprot id: I9ADH9
names: Similarity
messages: Belongs to the GerABKA family.

880478:THESIDRAFT1 RS03440
gene id: 880478:THESIDRAFT1_RS03440
uniprot id: I9ACH7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

880478:THESIDRAFT1 RS09940
gene id: 880478:THESIDRAFT1_RS09940
uniprot id: I9KVC7
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

880478:THESIDRAFT1 RS00825
gene id: 880478:THESIDRAFT1_RS00825
uniprot id: I9KQQ1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

880478:THESIDRAFT1 RS11700
gene id: 880478:THESIDRAFT1_RS11700
uniprot id: I9KW77
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

880478:THESIDRAFT1 RS07890
gene id: 880478:THESIDRAFT1_RS07890
uniprot id: I9KUB4
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

880478:THESIDRAFT1 RS12065
gene id: 880478:THESIDRAFT1_RS12065
uniprot id: I9KQR5
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

880478:THESIDRAFT1 RS10585
gene id: 880478:THESIDRAFT1_RS10585
uniprot id: I9KVL0
names: Similarity
messages: Belongs to the fabD family.

880478:THESIDRAFT1 RS00325
gene id: 880478:THESIDRAFT1_RS00325
uniprot id: I9KQF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

880478:THESIDRAFT1 RS03665
gene id: 880478:THESIDRAFT1_RS03665
uniprot id: I8QXM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

880478:THESIDRAFT1 RS05480
gene id: 880478:THESIDRAFT1_RS05480
uniprot id: I8R3W4
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

880478:THESIDRAFT1 RS05170
gene id: 880478:THESIDRAFT1_RS05170
uniprot id: I8QYC2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

880478:THESIDRAFT1 RS00970
gene id: 880478:THESIDRAFT1_RS00970
uniprot id: I8R1I9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

880478:THESIDRAFT1 RS05405
gene id: 880478:THESIDRAFT1_RS05405
uniprot id: I8R3V6
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

880478:THESIDRAFT1 RS06315
gene id: 880478:THESIDRAFT1_RS06315
uniprot id: I9AE15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

880478:THESIDRAFT1 RS02295
gene id: 880478:THESIDRAFT1_RS02295
uniprot id: I8QX40
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

880478:THESIDRAFT1 RS11130
gene id: 880478:THESIDRAFT1_RS11130
uniprot id: I8R124
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

880478:THESIDRAFT1 RS01870
gene id: 880478:THESIDRAFT1_RS01870
uniprot id: I9ABP2
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

880478:THESIDRAFT1 RS11915
gene id: 880478:THESIDRAFT1_RS11915
uniprot id: I8R1I6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

880478:THESIDRAFT1 RS00125
gene id: 880478:THESIDRAFT1_RS00125
uniprot id: I8QW08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS06160
gene id: 880478:THESIDRAFT1_RS06160
uniprot id: I9ADZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS02375
gene id: 880478:THESIDRAFT1_RS02375
uniprot id: I9KRJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched-chain polyamine synthase family.
messages: Cytoplasm
messages: Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.

880478:THESIDRAFT1 RS02790
gene id: 880478:THESIDRAFT1_RS02790
uniprot id: I9AC43
names: Similarity
messages: Belongs to the ComB family.

880478:THESIDRAFT1 RS12885
gene id: 880478:THESIDRAFT1_RS12885
uniprot id: I8R310
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

880478:THESIDRAFT1 RS06460
gene id: 880478:THESIDRAFT1_RS06460
uniprot id: I9KTU9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

880478:THESIDRAFT1 RS00335
gene id: 880478:THESIDRAFT1_RS00335
uniprot id: I9KQQ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

880478:THESIDRAFT1 RS09260
gene id: 880478:THESIDRAFT1_RS09260
uniprot id: I8R5Q4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS07650
gene id: 880478:THESIDRAFT1_RS07650
uniprot id: I9AER4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

880478:THESIDRAFT1 RS05500
gene id: 880478:THESIDRAFT1_RS05500
uniprot id: I9KT46
names: Similarity
messages: Belongs to the peptidase S8 family.

880478:THESIDRAFT1 RS01595
gene id: 880478:THESIDRAFT1_RS01595
uniprot id: I8QWN2
names: Similarity
messages: Belongs to the hemerythrin family.

880478:THESIDRAFT1 RS12455
gene id: 880478:THESIDRAFT1_RS12455
uniprot id: I9AHF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

880478:THESIDRAFT1 RS10775
gene id: 880478:THESIDRAFT1_RS10775
uniprot id: I9AGE4
names: Similarity
messages: Belongs to the FlgD family.

880478:THESIDRAFT1 RS00470
gene id: 880478:THESIDRAFT1_RS00470
uniprot id: I9KQI9
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

880478:THESIDRAFT1 RS03475
gene id: 880478:THESIDRAFT1_RS03475
uniprot id: I9ACI2
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

880478:THESIDRAFT1 RS01450
gene id: 880478:THESIDRAFT1_RS01450
uniprot id: I9ABF2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FBP aldolase/phosphatase family.
messages: Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
messages: Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.
messages: Homooctamer; dimer of tetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS05000
gene id: 880478:THESIDRAFT1_RS05000
uniprot id: I9KT66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

880478:THESIDRAFT1 RS06710
gene id: 880478:THESIDRAFT1_RS06710
uniprot id: I9AE85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

880478:THESIDRAFT1 RS05510
gene id: 880478:THESIDRAFT1_RS05510
uniprot id: I9KTF6
names: Similarity
messages: Belongs to the peptidase S41A family.

880478:THESIDRAFT1 RS07915
gene id: 880478:THESIDRAFT1_RS07915
uniprot id: I9KUB9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

880478:THESIDRAFT1 RS08805
gene id: 880478:THESIDRAFT1_RS08805
uniprot id: I9KUR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

880478:THESIDRAFT1 RS11135
gene id: 880478:THESIDRAFT1_RS11135
uniprot id: I9KVW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

880478:THESIDRAFT1 RS07075
gene id: 880478:THESIDRAFT1_RS07075
uniprot id: I9AEI4
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

880478:THESIDRAFT1 RS01120
gene id: 880478:THESIDRAFT1_RS01120
uniprot id: I9KQV3
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

880478:THESIDRAFT1 RS07470
gene id: 880478:THESIDRAFT1_RS07470
uniprot id: I9AEN8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS01925
gene id: 880478:THESIDRAFT1_RS01925
uniprot id: I8QWY0
names: Subcellular Location Annotation
messages: Cytoplasm

880478:THESIDRAFT1 RS08350
gene id: 880478:THESIDRAFT1_RS08350
uniprot id: I9KUI5
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

880478:THESIDRAFT1 RS12205
gene id: 880478:THESIDRAFT1_RS12205
uniprot id: I8R1P6
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS00620
gene id: 880478:THESIDRAFT1_RS00620
uniprot id: I9KQL7
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS06040
gene id: 880478:THESIDRAFT1_RS06040
uniprot id: I9ADW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

880478:THESIDRAFT1 RS01780
gene id: 880478:THESIDRAFT1_RS01780
uniprot id: I9KR82
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

880478:THESIDRAFT1 RS04240
gene id: 880478:THESIDRAFT1_RS04240
uniprot id: I9ACY0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

880478:THESIDRAFT1 RS10130
gene id: 880478:THESIDRAFT1_RS10130
uniprot id: I8R633
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

880478:THESIDRAFT1 RS00300
gene id: 880478:THESIDRAFT1_RS00300
uniprot id: I8QW30
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

880478:THESIDRAFT1 RS06885
gene id: 880478:THESIDRAFT1_RS06885
uniprot id: I9KU23
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS02720
gene id: 880478:THESIDRAFT1_RS02720
uniprot id: I8QXA9
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

880478:THESIDRAFT1 RS01115
gene id: 880478:THESIDRAFT1_RS01115
uniprot id: I8QWD5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

880478:THESIDRAFT1 RS11865
gene id: 880478:THESIDRAFT1_RS11865
uniprot id: I9AH19
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

880478:THESIDRAFT1 RS01830
gene id: 880478:THESIDRAFT1_RS01830
uniprot id: I8QWV3
names: Similarity
messages: Belongs to the BMP lipoprotein family.

880478:THESIDRAFT1 RS01850
gene id: 880478:THESIDRAFT1_RS01850
uniprot id: I9ABP0
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

880478:THESIDRAFT1 RS00400
gene id: 880478:THESIDRAFT1_RS00400
uniprot id: I8R196
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

880478:THESIDRAFT1 RS04550
gene id: 880478:THESIDRAFT1_RS04550
uniprot id: I9KSP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

880478:THESIDRAFT1 RS09180
gene id: 880478:THESIDRAFT1_RS09180
uniprot id: I9KUY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS06470
gene id: 880478:THESIDRAFT1_RS06470
uniprot id: I8QYU3
names: Similarity
messages: Belongs to the class-I fumarase family.

880478:THESIDRAFT1 RS04335
gene id: 880478:THESIDRAFT1_RS04335
uniprot id: I9KSI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS00785
gene id: 880478:THESIDRAFT1_RS00785
uniprot id: I9KQZ1
names: Similarity
messages: Belongs to the band 7/mec-2 family.

880478:THESIDRAFT1 RS02785
gene id: 880478:THESIDRAFT1_RS02785
uniprot id: I9KS09
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

880478:THESIDRAFT1 RS11710
gene id: 880478:THESIDRAFT1_RS11710
uniprot id: I9KWJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

880478:THESIDRAFT1 RS05280
gene id: 880478:THESIDRAFT1_RS05280
uniprot id: I8R3T5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

880478:THESIDRAFT1 RS09655
gene id: 880478:THESIDRAFT1_RS09655
uniprot id: I8R5W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS04165
gene id: 880478:THESIDRAFT1_RS04165
uniprot id: I8QXW3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

880478:THESIDRAFT1 RS09385
gene id: 880478:THESIDRAFT1_RS09385
uniprot id: I8R5S4
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS11860
gene id: 880478:THESIDRAFT1_RS11860
uniprot id: I9KWM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

880478:THESIDRAFT1 RS00045
gene id: 880478:THESIDRAFT1_RS00045
uniprot id: I9AAM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

880478:THESIDRAFT1 RS00485
gene id: 880478:THESIDRAFT1_RS00485
uniprot id: I9AAV7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

880478:THESIDRAFT1 RS02670
gene id: 880478:THESIDRAFT1_RS02670
uniprot id: I8QXA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS06960
gene id: 880478:THESIDRAFT1_RS06960
uniprot id: I9KU37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

880478:THESIDRAFT1 RS03670
gene id: 880478:THESIDRAFT1_RS03670
uniprot id: I9KS61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

880478:THESIDRAFT1 RS06515
gene id: 880478:THESIDRAFT1_RS06515
uniprot id: I9AE46
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

880478:THESIDRAFT1 RS11290
gene id: 880478:THESIDRAFT1_RS11290
uniprot id: I9KVZ6
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

880478:THESIDRAFT1 RS02140
gene id: 880478:THESIDRAFT1_RS02140
uniprot id: I9ABT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

880478:THESIDRAFT1 RS01920
gene id: 880478:THESIDRAFT1_RS01920
uniprot id: I9ABQ0
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS03205
gene id: 880478:THESIDRAFT1_RS03205
uniprot id: I8R2R3
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

880478:THESIDRAFT1 RS06475
gene id: 880478:THESIDRAFT1_RS06475
uniprot id: I9KTK9
names: Similarity
messages: Belongs to the class-I fumarase family.

880478:THESIDRAFT1 RS06200
gene id: 880478:THESIDRAFT1_RS06200
uniprot id: I9ADZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS12010
gene id: 880478:THESIDRAFT1_RS12010
uniprot id: I9KWP7
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

880478:THESIDRAFT1 RS11165
gene id: 880478:THESIDRAFT1_RS11165
uniprot id: I9KVX2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

880478:THESIDRAFT1 RS11375
gene id: 880478:THESIDRAFT1_RS11375
uniprot id: I8R175
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.

880478:THESIDRAFT1 RS06105
gene id: 880478:THESIDRAFT1_RS06105
uniprot id: I8R485
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

880478:THESIDRAFT1 RS08050
gene id: 880478:THESIDRAFT1_RS08050
uniprot id: I8R573
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS04900
gene id: 880478:THESIDRAFT1_RS04900
uniprot id: I9ADA9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

880478:THESIDRAFT1 RS12290
gene id: 880478:THESIDRAFT1_RS12290
uniprot id: I9KWV5
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

880478:THESIDRAFT1 RS04800
gene id: 880478:THESIDRAFT1_RS04800
uniprot id: I9AD95
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS03375
gene id: 880478:THESIDRAFT1_RS03375
uniprot id: I9KS15
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

880478:THESIDRAFT1 RS11370
gene id: 880478:THESIDRAFT1_RS11370
uniprot id: I9AGR2
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

880478:THESIDRAFT1 RS08280
gene id: 880478:THESIDRAFT1_RS08280
uniprot id: I9AF27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

880478:THESIDRAFT1 RS06015
gene id: 880478:THESIDRAFT1_RS06015
uniprot id: I8QYM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

880478:THESIDRAFT1 RS12895
gene id: 880478:THESIDRAFT1_RS12895
uniprot id: I8R345
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

880478:THESIDRAFT1 RS10695
gene id: 880478:THESIDRAFT1_RS10695
uniprot id: I9KW10
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

880478:THESIDRAFT1 RS10415
gene id: 880478:THESIDRAFT1_RS10415
uniprot id: I8R667
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS10510
gene id: 880478:THESIDRAFT1_RS10510
uniprot id: I9KVJ6
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

880478:THESIDRAFT1 RS02200
gene id: 880478:THESIDRAFT1_RS02200
uniprot id: I8R287
names: Similarity
messages: Belongs to the thioesterase PaaI family.

880478:THESIDRAFT1 RS01840
gene id: 880478:THESIDRAFT1_RS01840
uniprot id: I9KQR5
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

880478:THESIDRAFT1 RS05250
gene id: 880478:THESIDRAFT1_RS05250
uniprot id: I9KT01
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS08185
gene id: 880478:THESIDRAFT1_RS08185
uniprot id: I8QZM2
names: Similarity
messages: Belongs to the P(II) protein family.

880478:THESIDRAFT1 RS04330
gene id: 880478:THESIDRAFT1_RS04330
uniprot id: I8QXY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS09750
gene id: 880478:THESIDRAFT1_RS09750
uniprot id: I8R5Y8
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS01025
gene id: 880478:THESIDRAFT1_RS01025
uniprot id: I9KR36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides.
messages: Homodimer.
messages: Monomer.
messages: Secreted

880478:THESIDRAFT1 RS03770
gene id: 880478:THESIDRAFT1_RS03770
uniprot id: I9KS81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

880478:THESIDRAFT1 RS08100
gene id: 880478:THESIDRAFT1_RS08100
uniprot id: I9AF01
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

880478:THESIDRAFT1 RS10000
gene id: 880478:THESIDRAFT1_RS10000
uniprot id: I8R615
names: Subcellular Location Annotation
messages: Cytoplasm

880478:THESIDRAFT1 RS03155
gene id: 880478:THESIDRAFT1_RS03155
uniprot id: I8R2Q2
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

880478:THESIDRAFT1 RS10485
gene id: 880478:THESIDRAFT1_RS10485
uniprot id: I9KVJ3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

880478:THESIDRAFT1 RS02760
gene id: 880478:THESIDRAFT1_RS02760
uniprot id: I9KS05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

880478:THESIDRAFT1 RS03940
gene id: 880478:THESIDRAFT1_RS03940
uniprot id: I9ACS1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

880478:THESIDRAFT1 RS06455
gene id: 880478:THESIDRAFT1_RS06455
uniprot id: I8R4E0
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS03270
gene id: 880478:THESIDRAFT1_RS03270
uniprot id: I8QXI8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

880478:THESIDRAFT1 RS10590
gene id: 880478:THESIDRAFT1_RS10590
uniprot id: I8R689
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

880478:THESIDRAFT1 RS03575
gene id: 880478:THESIDRAFT1_RS03575
uniprot id: I8R2X4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

880478:THESIDRAFT1 RS11845
gene id: 880478:THESIDRAFT1_RS11845
uniprot id: I8R1H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

880478:THESIDRAFT1 RS11105
gene id: 880478:THESIDRAFT1_RS11105
uniprot id: I8R119
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

880478:THESIDRAFT1 RS10925
gene id: 880478:THESIDRAFT1_RS10925
uniprot id: I9AGG9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS12395
gene id: 880478:THESIDRAFT1_RS12395
uniprot id: I9KWX1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

880478:THESIDRAFT1 RS09250
gene id: 880478:THESIDRAFT1_RS09250
uniprot id: I8R048
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

880478:THESIDRAFT1 RS07405
gene id: 880478:THESIDRAFT1_RS07405
uniprot id: I9KU39
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

880478:THESIDRAFT1 RS08975
gene id: 880478:THESIDRAFT1_RS08975
uniprot id: I9KUU7
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS10955
gene id: 880478:THESIDRAFT1_RS10955
uniprot id: I8R0Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

880478:THESIDRAFT1 RS11805
gene id: 880478:THESIDRAFT1_RS11805
uniprot id: I8R6T1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

880478:THESIDRAFT1 RS03830
gene id: 880478:THESIDRAFT1_RS03830
uniprot id: I9KSJ5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

880478:THESIDRAFT1 RS08795
gene id: 880478:THESIDRAFT1_RS08795
uniprot id: I9AFC7
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

880478:THESIDRAFT1 RS05975
gene id: 880478:THESIDRAFT1_RS05975
uniprot id: I8R461
names: Similarity
messages: Belongs to the ParB family.

880478:THESIDRAFT1 RS03695
gene id: 880478:THESIDRAFT1_RS03695
uniprot id: I9KS66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

880478:THESIDRAFT1 RS12365
gene id: 880478:THESIDRAFT1_RS12365
uniprot id: I8R739
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

880478:THESIDRAFT1 RS10340
gene id: 880478:THESIDRAFT1_RS10340
uniprot id: I9KVH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS05440
gene id: 880478:THESIDRAFT1_RS05440
uniprot id: I9ADJ9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

880478:THESIDRAFT1 RS02605
gene id: 880478:THESIDRAFT1_RS02605
uniprot id: I8R2E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS10755
gene id: 880478:THESIDRAFT1_RS10755
uniprot id: I8R0W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cytoplasm

880478:THESIDRAFT1 RS10830
gene id: 880478:THESIDRAFT1_RS10830
uniprot id: I8R0X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

880478:THESIDRAFT1 RS08765
gene id: 880478:THESIDRAFT1_RS08765
uniprot id: I9KV05
names: Similarity
messages: Belongs to the UPF0758 family.

880478:THESIDRAFT1 RS10960
gene id: 880478:THESIDRAFT1_RS10960
uniprot id: I9KVT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

880478:THESIDRAFT1 RS09900
gene id: 880478:THESIDRAFT1_RS09900
uniprot id: I9AG08
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

880478:THESIDRAFT1 RS10400
gene id: 880478:THESIDRAFT1_RS10400
uniprot id: I9AG78
names: Similarity
messages: Belongs to the RemA family.

880478:THESIDRAFT1 RS10550
gene id: 880478:THESIDRAFT1_RS10550
uniprot id: I9AGA6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

880478:THESIDRAFT1 RS02655
gene id: 880478:THESIDRAFT1_RS02655
uniprot id: I8R2F5
names: Function
names: Similarity
messages: Belongs to the UxaE family.
messages: Catalyzes the epimerization of D-tagaturonate (D-TagA) to D-fructuronate (D-FruA).

880478:THESIDRAFT1 RS00220
gene id: 880478:THESIDRAFT1_RS00220
uniprot id: I8R164
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

880478:THESIDRAFT1 RS09290
gene id: 880478:THESIDRAFT1_RS09290
uniprot id: I9KV91
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

880478:THESIDRAFT1 RS01700
gene id: 880478:THESIDRAFT1_RS01700
uniprot id: I9KR67
names: Similarity
messages: Belongs to the phosphopentomutase family.

880478:THESIDRAFT1 RS00180
gene id: 880478:THESIDRAFT1_RS00180
uniprot id: I8QW15
names: Similarity
messages: Belongs to the asparagine synthetase family.

880478:THESIDRAFT1 RS08020
gene id: 880478:THESIDRAFT1_RS08020
uniprot id: I8R568
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

880478:THESIDRAFT1 RS09595
gene id: 880478:THESIDRAFT1_RS09595
uniprot id: I9AFT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

880478:THESIDRAFT1 RS05390
gene id: 880478:THESIDRAFT1_RS05390
uniprot id: I9ADJ1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

880478:THESIDRAFT1 RS07645
gene id: 880478:THESIDRAFT1_RS07645
uniprot id: I9KUH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

880478:THESIDRAFT1 RS10980
gene id: 880478:THESIDRAFT1_RS10980
uniprot id: I8R0Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

880478:THESIDRAFT1 RS01415
gene id: 880478:THESIDRAFT1_RS01415
uniprot id: I8R1S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

880478:THESIDRAFT1 RS08335
gene id: 880478:THESIDRAFT1_RS08335
uniprot id: I9KUT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

880478:THESIDRAFT1 RS05555
gene id: 880478:THESIDRAFT1_RS05555
uniprot id: I8R3Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

880478:THESIDRAFT1 RS11555
gene id: 880478:THESIDRAFT1_RS11555
uniprot id: I8R6N9
names: Similarity
messages: Belongs to the peptidase M24B family.

880478:THESIDRAFT1 RS04785
gene id: 880478:THESIDRAFT1_RS04785
uniprot id: I9KST2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

880478:THESIDRAFT1 RS12180
gene id: 880478:THESIDRAFT1_RS12180
uniprot id: I8R1P1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

880478:THESIDRAFT1 RS01980
gene id: 880478:THESIDRAFT1_RS01980
uniprot id: I9KRD8
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS11565
gene id: 880478:THESIDRAFT1_RS11565
uniprot id: I9AGV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

880478:THESIDRAFT1 RS12610
gene id: 880478:THESIDRAFT1_RS12610
uniprot id: I9KX04
names: Similarity
messages: Belongs to the asparagine synthetase family.

880478:THESIDRAFT1 RS02700
gene id: 880478:THESIDRAFT1_RS02700
uniprot id: I9KRQ1
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

880478:THESIDRAFT1 RS07030
gene id: 880478:THESIDRAFT1_RS07030
uniprot id: I8QZ79
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

880478:THESIDRAFT1 RS10565
gene id: 880478:THESIDRAFT1_RS10565
uniprot id: I8R686
names: Function
names: Similarity
messages: Belongs to the FapR family.
messages: Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism.

880478:THESIDRAFT1 RS08785
gene id: 880478:THESIDRAFT1_RS08785
uniprot id: I8R5I2
names: Similarity
messages: Belongs to the transpeptidase family.

880478:THESIDRAFT1 RS08365
gene id: 880478:THESIDRAFT1_RS08365
uniprot id: I9AF40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

880478:THESIDRAFT1 RS08985
gene id: 880478:THESIDRAFT1_RS08985
uniprot id: I9KV40
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

880478:THESIDRAFT1 RS06635
gene id: 880478:THESIDRAFT1_RS06635
uniprot id: I9AE70
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS07380
gene id: 880478:THESIDRAFT1_RS07380
uniprot id: I9KU35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

880478:THESIDRAFT1 RS09020
gene id: 880478:THESIDRAFT1_RS09020
uniprot id: I8R006
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS06795
gene id: 880478:THESIDRAFT1_RS06795
uniprot id: I9KTR0
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

880478:THESIDRAFT1 RS02405
gene id: 880478:THESIDRAFT1_RS02405
uniprot id: I8R2B5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

880478:THESIDRAFT1 RS05835
gene id: 880478:THESIDRAFT1_RS05835
uniprot id: I8R437
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS06065
gene id: 880478:THESIDRAFT1_RS06065
uniprot id: I9ADX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

880478:THESIDRAFT1 RS09540
gene id: 880478:THESIDRAFT1_RS09540
uniprot id: I9KVD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell membrane
messages: Essential cell division protein.
messages: Membrane

880478:THESIDRAFT1 RS04230
gene id: 880478:THESIDRAFT1_RS04230
uniprot id: I8R393
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

880478:THESIDRAFT1 RS09555
gene id: 880478:THESIDRAFT1_RS09555
uniprot id: I9KV54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

880478:THESIDRAFT1 RS11325
gene id: 880478:THESIDRAFT1_RS11325
uniprot id: I8R165
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

880478:THESIDRAFT1 RS03305
gene id: 880478:THESIDRAFT1_RS03305
uniprot id: I8R2T2
names: Similarity
messages: Belongs to the UPF0047 family.

880478:THESIDRAFT1 RS07545
gene id: 880478:THESIDRAFT1_RS07545
uniprot id: I9KUG0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

880478:THESIDRAFT1 RS12210
gene id: 880478:THESIDRAFT1_RS12210
uniprot id: I9KWH7
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

880478:THESIDRAFT1 RS08390
gene id: 880478:THESIDRAFT1_RS08390
uniprot id: I9AF47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

880478:THESIDRAFT1 RS07480
gene id: 880478:THESIDRAFT1_RS07480
uniprot id: I9KU46
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

880478:THESIDRAFT1 RS00465
gene id: 880478:THESIDRAFT1_RS00465
uniprot id: I8QW55
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS05245
gene id: 880478:THESIDRAFT1_RS05245
uniprot id: I8QYD4
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS03950
gene id: 880478:THESIDRAFT1_RS03950
uniprot id: I9KSB6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

880478:THESIDRAFT1 RS01375
gene id: 880478:THESIDRAFT1_RS01375
uniprot id: I9ABD5
names: Similarity
messages: Belongs to the OsmC/Ohr family.

880478:THESIDRAFT1 RS01875
gene id: 880478:THESIDRAFT1_RS01875
uniprot id: I8QWW8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

880478:THESIDRAFT1 RS07215
gene id: 880478:THESIDRAFT1_RS07215
uniprot id: I9KUB3
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

880478:THESIDRAFT1 RS02390
gene id: 880478:THESIDRAFT1_RS02390
uniprot id: I9ABX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

880478:THESIDRAFT1 RS02755
gene id: 880478:THESIDRAFT1_RS02755
uniprot id: I8R2H2
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

880478:THESIDRAFT1 RS02065
gene id: 880478:THESIDRAFT1_RS02065
uniprot id: I9KRP5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS02920
gene id: 880478:THESIDRAFT1_RS02920
uniprot id: I9AC68
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

880478:THESIDRAFT1 RS10525
gene id: 880478:THESIDRAFT1_RS10525
uniprot id: I9AGA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

880478:THESIDRAFT1 RS07795
gene id: 880478:THESIDRAFT1_RS07795
uniprot id: I8R541
names: Similarity
messages: Belongs to the asp23 family.

880478:THESIDRAFT1 RS05825
gene id: 880478:THESIDRAFT1_RS05825
uniprot id: I8QYK7
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS10105
gene id: 880478:THESIDRAFT1_RS10105
uniprot id: I9KVR2
names: Similarity
messages: Belongs to the UPF0047 family.

880478:THESIDRAFT1 RS10275
gene id: 880478:THESIDRAFT1_RS10275
uniprot id: I9KVG6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS07550
gene id: 880478:THESIDRAFT1_RS07550
uniprot id: I9AEQ0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

880478:THESIDRAFT1 RS03180
gene id: 880478:THESIDRAFT1_RS03180
uniprot id: I8R2Q7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

880478:THESIDRAFT1 RS09115
gene id: 880478:THESIDRAFT1_RS09115
uniprot id: I9AFI7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

880478:THESIDRAFT1 RS08695
gene id: 880478:THESIDRAFT1_RS08695
uniprot id: I9AFA7
names: Similarity
messages: Belongs to the transglycosylase Slt family.

880478:THESIDRAFT1 RS07800
gene id: 880478:THESIDRAFT1_RS07800
uniprot id: I9KUK3
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

880478:THESIDRAFT1 RS04295
gene id: 880478:THESIDRAFT1_RS04295
uniprot id: I9KSS6
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

880478:THESIDRAFT1 RS03845
gene id: 880478:THESIDRAFT1_RS03845
uniprot id: I9KS96
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

880478:THESIDRAFT1 RS03070
gene id: 880478:THESIDRAFT1_RS03070
uniprot id: I8QXF8
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

880478:THESIDRAFT1 RS04310
gene id: 880478:THESIDRAFT1_RS04310
uniprot id: I9KSI4
names: Similarity
messages: Belongs to the glycosyl hydrolase 66 family.

880478:THESIDRAFT1 RS06765
gene id: 880478:THESIDRAFT1_RS06765
uniprot id: I8QYZ7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

880478:THESIDRAFT1 RS10490
gene id: 880478:THESIDRAFT1_RS10490
uniprot id: I8R678
names: Similarity
messages: Belongs to the asp23 family.

880478:THESIDRAFT1 RS03340
gene id: 880478:THESIDRAFT1_RS03340
uniprot id: I9ACF7
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

880478:THESIDRAFT1 RS02085
gene id: 880478:THESIDRAFT1_RS02085
uniprot id: I8R268
names: Function
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

880478:THESIDRAFT1 RS10250
gene id: 880478:THESIDRAFT1_RS10250
uniprot id: I9KVG3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

880478:THESIDRAFT1 RS07410
gene id: 880478:THESIDRAFT1_RS07410
uniprot id: I8R4Z4
names: Subcellular Location Annotation
messages: Cytoplasm

880478:THESIDRAFT1 RS03630
gene id: 880478:THESIDRAFT1_RS03630
uniprot id: I9KSF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

880478:THESIDRAFT1 RS05310
gene id: 880478:THESIDRAFT1_RS05310
uniprot id: I9KTB9
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

880478:THESIDRAFT1 RS10280
gene id: 880478:THESIDRAFT1_RS10280
uniprot id: I8R654
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

880478:THESIDRAFT1 RS12155
gene id: 880478:THESIDRAFT1_RS12155
uniprot id: I8R1N6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

880478:THESIDRAFT1 RS05995
gene id: 880478:THESIDRAFT1_RS05995
uniprot id: I9KTD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

880478:THESIDRAFT1 RS12390
gene id: 880478:THESIDRAFT1_RS12390
uniprot id: I8R742
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

880478:THESIDRAFT1 RS04645
gene id: 880478:THESIDRAFT1_RS04645
uniprot id: I9AD73
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS02515
gene id: 880478:THESIDRAFT1_RS02515
uniprot id: I9ABZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS07255
gene id: 880478:THESIDRAFT1_RS07255
uniprot id: I9KU21
names: Similarity
messages: Belongs to the acylphosphatase family.

880478:THESIDRAFT1 RS11480
gene id: 880478:THESIDRAFT1_RS11480
uniprot id: I8R6M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

880478:THESIDRAFT1 RS07910
gene id: 880478:THESIDRAFT1_RS07910
uniprot id: I8QZJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

880478:THESIDRAFT1 RS06120
gene id: 880478:THESIDRAFT1_RS06120
uniprot id: I8QYP2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS02305
gene id: 880478:THESIDRAFT1_RS02305
uniprot id: I8R2A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

880478:THESIDRAFT1 RS02000
gene id: 880478:THESIDRAFT1_RS02000
uniprot id: I8QWZ3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

880478:THESIDRAFT1 RS06155
gene id: 880478:THESIDRAFT1_RS06155
uniprot id: I8R493
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

880478:THESIDRAFT1 RS01330
gene id: 880478:THESIDRAFT1_RS01330
uniprot id: I8QWH4
names: Subcellular Location Annotation
messages: Cytoplasm

880478:THESIDRAFT1 RS02540
gene id: 880478:THESIDRAFT1_RS02540
uniprot id: I9AC00
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

880478:THESIDRAFT1 RS10760
gene id: 880478:THESIDRAFT1_RS10760
uniprot id: I9KVP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS08270
gene id: 880478:THESIDRAFT1_RS08270
uniprot id: I8R599
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

880478:THESIDRAFT1 RS03755
gene id: 880478:THESIDRAFT1_RS03755
uniprot id: I9KSI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

880478:THESIDRAFT1 RS05160
gene id: 880478:THESIDRAFT1_RS05160
uniprot id: I9KT94
names: Similarity
messages: Belongs to the HepT RNase toxin family.

880478:THESIDRAFT1 RS11380
gene id: 880478:THESIDRAFT1_RS11380
uniprot id: I9KW16
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

880478:THESIDRAFT1 RS07270
gene id: 880478:THESIDRAFT1_RS07270
uniprot id: I9AEL3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

880478:THESIDRAFT1 RS00780
gene id: 880478:THESIDRAFT1_RS00780
uniprot id: I8R1F9
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS11125
gene id: 880478:THESIDRAFT1_RS11125
uniprot id: I9AGL1
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

880478:THESIDRAFT1 RS11940
gene id: 880478:THESIDRAFT1_RS11940
uniprot id: I8R1J2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

880478:THESIDRAFT1 RS01660
gene id: 880478:THESIDRAFT1_RS01660
uniprot id: I9KRF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS09620
gene id: 880478:THESIDRAFT1_RS09620
uniprot id: I8R0C3
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

880478:THESIDRAFT1 RS03870
gene id: 880478:THESIDRAFT1_RS03870
uniprot id: I8QXQ8
names: Similarity
messages: Belongs to the DtxR/MntR family.

880478:THESIDRAFT1 RS08200
gene id: 880478:THESIDRAFT1_RS08200
uniprot id: I9KUR0
names: Similarity
messages: Belongs to the glutamate synthase family.

880478:THESIDRAFT1 RS01080
gene id: 880478:THESIDRAFT1_RS01080
uniprot id: I9KR44
names: Similarity
messages: Belongs to the CapA family.

880478:THESIDRAFT1 RS08400
gene id: 880478:THESIDRAFT1_RS08400
uniprot id: I9KUJ6
names: Similarity
messages: Belongs to the EamA transporter family.

880478:THESIDRAFT1 RS06135
gene id: 880478:THESIDRAFT1_RS06135
uniprot id: I9KTP9
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

880478:THESIDRAFT1 RS01370
gene id: 880478:THESIDRAFT1_RS01370
uniprot id: I9KR95
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

880478:THESIDRAFT1 RS09255
gene id: 880478:THESIDRAFT1_RS09255
uniprot id: I9KV00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

880478:THESIDRAFT1 RS08965
gene id: 880478:THESIDRAFT1_RS08965
uniprot id: I9AFF7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

880478:THESIDRAFT1 RS06620
gene id: 880478:THESIDRAFT1_RS06620
uniprot id: I9KTM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

880478:THESIDRAFT1 RS03565
gene id: 880478:THESIDRAFT1_RS03565
uniprot id: I8QXL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

880478:THESIDRAFT1 RS01110
gene id: 880478:THESIDRAFT1_RS01110
uniprot id: I9AB84
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

880478:THESIDRAFT1 RS02395
gene id: 880478:THESIDRAFT1_RS02395
uniprot id: I8QX57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS04085
gene id: 880478:THESIDRAFT1_RS04085
uniprot id: I9ACV0
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

880478:THESIDRAFT1 RS06325
gene id: 880478:THESIDRAFT1_RS06325
uniprot id: I9KTI9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

880478:THESIDRAFT1 RS03635
gene id: 880478:THESIDRAFT1_RS03635
uniprot id: I9ACK7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

880478:THESIDRAFT1 RS10015
gene id: 880478:THESIDRAFT1_RS10015
uniprot id: I8R0L2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS08005
gene id: 880478:THESIDRAFT1_RS08005
uniprot id: I9AEY4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

880478:THESIDRAFT1 RS02235
gene id: 880478:THESIDRAFT1_RS02235
uniprot id: I9KRS4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

880478:THESIDRAFT1 RS06330
gene id: 880478:THESIDRAFT1_RS06330
uniprot id: I8R4C3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

880478:THESIDRAFT1 RS11680
gene id: 880478:THESIDRAFT1_RS11680
uniprot id: I8R6R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

880478:THESIDRAFT1 RS08690
gene id: 880478:THESIDRAFT1_RS08690
uniprot id: I9KUZ2
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

880478:THESIDRAFT1 RS10350
gene id: 880478:THESIDRAFT1_RS10350
uniprot id: I9KVV2
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

880478:THESIDRAFT1 RS11160
gene id: 880478:THESIDRAFT1_RS11160
uniprot id: I8R128
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

880478:THESIDRAFT1 RS11475
gene id: 880478:THESIDRAFT1_RS11475
uniprot id: I9KW34
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

880478:THESIDRAFT1 RS07955
gene id: 880478:THESIDRAFT1_RS07955
uniprot id: I9AEX6
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

880478:THESIDRAFT1 RS01070
gene id: 880478:THESIDRAFT1_RS01070
uniprot id: I9KQU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS04975
gene id: 880478:THESIDRAFT1_RS04975
uniprot id: I9KT62
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

880478:THESIDRAFT1 RS00820
gene id: 880478:THESIDRAFT1_RS00820
uniprot id: I8QWA8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

880478:THESIDRAFT1 RS03005
gene id: 880478:THESIDRAFT1_RS03005
uniprot id: I9KRV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

880478:THESIDRAFT1 RS07490
gene id: 880478:THESIDRAFT1_RS07490
uniprot id: I9KUF2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

880478:THESIDRAFT1 RS09150
gene id: 880478:THESIDRAFT1_RS09150
uniprot id: I8R032
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

880478:THESIDRAFT1 RS11580
gene id: 880478:THESIDRAFT1_RS11580
uniprot id: I8R6P3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

880478:THESIDRAFT1 RS07820
gene id: 880478:THESIDRAFT1_RS07820
uniprot id: I8R544
names: Function
names: Similarity
names: Subunit
messages: Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.
messages: Belongs to the HutP family.
messages: Homohexamer.

880478:THESIDRAFT1 RS02260
gene id: 880478:THESIDRAFT1_RS02260
uniprot id: I9ABV1
names: Similarity
messages: Belongs to the UPF0251 family.

880478:THESIDRAFT1 RS00215
gene id: 880478:THESIDRAFT1_RS00215
uniprot id: I9KQD9
names: Similarity
messages: Belongs to the bacterial flagellin family.

880478:THESIDRAFT1 RS03080
gene id: 880478:THESIDRAFT1_RS03080
uniprot id: I8R2N7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

880478:THESIDRAFT1 RS10745
gene id: 880478:THESIDRAFT1_RS10745
uniprot id: I9KW19
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

880478:THESIDRAFT1 RS05800
gene id: 880478:THESIDRAFT1_RS05800
uniprot id: I9KTA2
names: Similarity
messages: Belongs to the CapA family.

880478:THESIDRAFT1 RS07100
gene id: 880478:THESIDRAFT1_RS07100
uniprot id: I8QZ99
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS07065
gene id: 880478:THESIDRAFT1_RS07065
uniprot id: I8R4U0
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

880478:THESIDRAFT1 RS06220
gene id: 880478:THESIDRAFT1_RS06220
uniprot id: I9KTR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS05550
gene id: 880478:THESIDRAFT1_RS05550
uniprot id: I9KT56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

880478:THESIDRAFT1 RS05665
gene id: 880478:THESIDRAFT1_RS05665
uniprot id: I9ADP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

880478:THESIDRAFT1 RS01685
gene id: 880478:THESIDRAFT1_RS01685
uniprot id: I9KRF5
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

880478:THESIDRAFT1 RS05010
gene id: 880478:THESIDRAFT1_RS05010
uniprot id: I8QYA3
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS05670
gene id: 880478:THESIDRAFT1_RS05670
uniprot id: I9KT78
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS00790
gene id: 880478:THESIDRAFT1_RS00790
uniprot id: I9AB17
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

880478:THESIDRAFT1 RS10630
gene id: 880478:THESIDRAFT1_RS10630
uniprot id: I8R0T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

880478:THESIDRAFT1 RS11495
gene id: 880478:THESIDRAFT1_RS11495
uniprot id: I8R1A3
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

880478:THESIDRAFT1 RS10905
gene id: 880478:THESIDRAFT1_RS10905
uniprot id: I8R0Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

880478:THESIDRAFT1 RS09470
gene id: 880478:THESIDRAFT1_RS09470
uniprot id: I9AFR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

880478:THESIDRAFT1 RS11075
gene id: 880478:THESIDRAFT1_RS11075
uniprot id: I9AGK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

880478:THESIDRAFT1 RS10265
gene id: 880478:THESIDRAFT1_RS10265
uniprot id: I9AG60
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

880478:THESIDRAFT1 RS02510
gene id: 880478:THESIDRAFT1_RS02510
uniprot id: I9KRW5
names: Similarity
messages: Belongs to the glycosyl hydrolase.

880478:THESIDRAFT1 RS09360
gene id: 880478:THESIDRAFT1_RS09360
uniprot id: I8R5S0
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.

880478:THESIDRAFT1 RS11035
gene id: 880478:THESIDRAFT1_RS11035
uniprot id: I9KVU5
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

880478:THESIDRAFT1 RS07995
gene id: 880478:THESIDRAFT1_RS07995
uniprot id: I8R564
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

880478:THESIDRAFT1 RS00040
gene id: 880478:THESIDRAFT1_RS00040
uniprot id: I9KQK0
names: Similarity
messages: Belongs to the carbamate kinase family.

880478:THESIDRAFT1 RS06655
gene id: 880478:THESIDRAFT1_RS06655
uniprot id: I9KTX9
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

880478:THESIDRAFT1 RS10390
gene id: 880478:THESIDRAFT1_RS10390
uniprot id: I8R664
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS08790
gene id: 880478:THESIDRAFT1_RS08790
uniprot id: I9KV09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

880478:THESIDRAFT1 RS11920
gene id: 880478:THESIDRAFT1_RS11920
uniprot id: I9KWC1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

880478:THESIDRAFT1 RS06560
gene id: 880478:THESIDRAFT1_RS06560
uniprot id: I9KTW3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

880478:THESIDRAFT1 RS02505
gene id: 880478:THESIDRAFT1_RS02505
uniprot id: I8R2D2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

880478:THESIDRAFT1 RS00495
gene id: 880478:THESIDRAFT1_RS00495
uniprot id: I9KQJ3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

880478:THESIDRAFT1 RS00035
gene id: 880478:THESIDRAFT1_RS00035
uniprot id: I8R135
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

880478:THESIDRAFT1 RS12570
gene id: 880478:THESIDRAFT1_RS12570
uniprot id: I8R760
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

880478:THESIDRAFT1 RS07285
gene id: 880478:THESIDRAFT1_RS07285
uniprot id: I8R4X7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

880478:THESIDRAFT1 RS03135
gene id: 880478:THESIDRAFT1_RS03135
uniprot id: I9KS68
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS06420
gene id: 880478:THESIDRAFT1_RS06420
uniprot id: I8QYT6
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

880478:THESIDRAFT1 RS06820
gene id: 880478:THESIDRAFT1_RS06820
uniprot id: I9KTR3
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

880478:THESIDRAFT1 RS03395
gene id: 880478:THESIDRAFT1_RS03395
uniprot id: I8QXK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Probably a homodimer.

880478:THESIDRAFT1 RS05930
gene id: 880478:THESIDRAFT1_RS05930
uniprot id: I9KTL9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

880478:THESIDRAFT1 RS06850
gene id: 880478:THESIDRAFT1_RS06850
uniprot id: I9KTR8
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

880478:THESIDRAFT1 RS08360
gene id: 880478:THESIDRAFT1_RS08360
uniprot id: I9KUT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

880478:THESIDRAFT1 RS08800
gene id: 880478:THESIDRAFT1_RS08800
uniprot id: I8QZW9
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

880478:THESIDRAFT1 RS06735
gene id: 880478:THESIDRAFT1_RS06735
uniprot id: I9AE90
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS04175
gene id: 880478:THESIDRAFT1_RS04175
uniprot id: I8R384
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

880478:THESIDRAFT1 RS06835
gene id: 880478:THESIDRAFT1_RS06835
uniprot id: I9AEA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

880478:THESIDRAFT1 RS06610
gene id: 880478:THESIDRAFT1_RS06610
uniprot id: I9AE64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS05625
gene id: 880478:THESIDRAFT1_RS05625
uniprot id: I9KT69
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

880478:THESIDRAFT1 RS10560
gene id: 880478:THESIDRAFT1_RS10560
uniprot id: I9KVK6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

880478:THESIDRAFT1 RS11310
gene id: 880478:THESIDRAFT1_RS11310
uniprot id: I9KW01
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

880478:THESIDRAFT1 RS09450
gene id: 880478:THESIDRAFT1_RS09450
uniprot id: I9KV36
names: Similarity
messages: Belongs to the NadC/ModD family.

880478:THESIDRAFT1 RS03805
gene id: 880478:THESIDRAFT1_RS03805
uniprot id: I9KSJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

880478:THESIDRAFT1 RS01490
gene id: 880478:THESIDRAFT1_RS01490
uniprot id: I8R1T2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS01990
gene id: 880478:THESIDRAFT1_RS01990
uniprot id: I9KRN2
names: Subcellular Location Annotation
messages: Cytoplasm

880478:THESIDRAFT1 RS06080
gene id: 880478:THESIDRAFT1_RS06080
uniprot id: I8R479
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

880478:THESIDRAFT1 RS06865
gene id: 880478:THESIDRAFT1_RS06865
uniprot id: I9AEB3
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

880478:THESIDRAFT1 RS09465
gene id: 880478:THESIDRAFT1_RS09465
uniprot id: I9KVC1
names: Similarity
messages: Belongs to the peptidase C40 family.

880478:THESIDRAFT1 RS03040
gene id: 880478:THESIDRAFT1_RS03040
uniprot id: I9AC95
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS07090
gene id: 880478:THESIDRAFT1_RS07090
uniprot id: I8R4U4
names: Similarity
messages: Belongs to the manganese catalase family.

880478:THESIDRAFT1 RS10795
gene id: 880478:THESIDRAFT1_RS10795
uniprot id: I9KW29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

880478:THESIDRAFT1 RS05410
gene id: 880478:THESIDRAFT1_RS05410
uniprot id: I9KTD8
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

880478:THESIDRAFT1 RS01765
gene id: 880478:THESIDRAFT1_RS01765
uniprot id: I9KRG7
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS06855
gene id: 880478:THESIDRAFT1_RS06855
uniprot id: I8R4L3
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

880478:THESIDRAFT1 RS07010
gene id: 880478:THESIDRAFT1_RS07010
uniprot id: I9AEE0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

880478:THESIDRAFT1 RS06975
gene id: 880478:THESIDRAFT1_RS06975
uniprot id: I8R4N9
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

880478:THESIDRAFT1 RS06405
gene id: 880478:THESIDRAFT1_RS06405
uniprot id: I8R4D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS06785
gene id: 880478:THESIDRAFT1_RS06785
uniprot id: I9AEA0
names: Similarity
messages: Belongs to the HypE family.

880478:THESIDRAFT1 RS00860
gene id: 880478:THESIDRAFT1_RS00860
uniprot id: I9KQQ6
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

880478:THESIDRAFT1 RS06940
gene id: 880478:THESIDRAFT1_RS06940
uniprot id: I9AEC6
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

880478:THESIDRAFT1 RS11225
gene id: 880478:THESIDRAFT1_RS11225
uniprot id: I9KWA9
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

880478:THESIDRAFT1 RS11660
gene id: 880478:THESIDRAFT1_RS11660
uniprot id: I9KWJ2
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

880478:THESIDRAFT1 RS05790
gene id: 880478:THESIDRAFT1_RS05790
uniprot id: I9ADS0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS12350
gene id: 880478:THESIDRAFT1_RS12350
uniprot id: I9AHE1
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

880478:THESIDRAFT1 RS07060
gene id: 880478:THESIDRAFT1_RS07060
uniprot id: I9KTY3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS00440
gene id: 880478:THESIDRAFT1_RS00440
uniprot id: I8QW53
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

880478:THESIDRAFT1 RS09960
gene id: 880478:THESIDRAFT1_RS09960
uniprot id: I8R0K3
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

880478:THESIDRAFT1 RS06545
gene id: 880478:THESIDRAFT1_RS06545
uniprot id: I8QYV6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

880478:THESIDRAFT1 RS07340
gene id: 880478:THESIDRAFT1_RS07340
uniprot id: I9KU32
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

880478:THESIDRAFT1 RS04100
gene id: 880478:THESIDRAFT1_RS04100
uniprot id: I8R372
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

880478:THESIDRAFT1 RS01665
gene id: 880478:THESIDRAFT1_RS01665
uniprot id: I9ABJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

880478:THESIDRAFT1 RS08535
gene id: 880478:THESIDRAFT1_RS08535
uniprot id: I8R5E1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

880478:THESIDRAFT1 RS08175
gene id: 880478:THESIDRAFT1_RS08175
uniprot id: I9KUQ4
names: Similarity
messages: Belongs to the glutamine synthetase family.

880478:THESIDRAFT1 RS06210
gene id: 880478:THESIDRAFT1_RS06210
uniprot id: I9KTH3
names: Similarity
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family.

880478:THESIDRAFT1 RS10420
gene id: 880478:THESIDRAFT1_RS10420
uniprot id: I9KVW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

880478:THESIDRAFT1 RS05020
gene id: 880478:THESIDRAFT1_RS05020
uniprot id: I8R3Q5
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

880478:THESIDRAFT1 RS00615
gene id: 880478:THESIDRAFT1_RS00615
uniprot id: I8QW77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS11485
gene id: 880478:THESIDRAFT1_RS11485
uniprot id: I9KWG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

880478:THESIDRAFT1 RS06575
gene id: 880478:THESIDRAFT1_RS06575
uniprot id: I8R4F5
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

880478:THESIDRAFT1 RS04655
gene id: 880478:THESIDRAFT1_RS04655
uniprot id: I9KSR6
names: Similarity
messages: Belongs to the GSP E family.

880478:THESIDRAFT1 RS11065
gene id: 880478:THESIDRAFT1_RS11065
uniprot id: I8R6F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

880478:THESIDRAFT1 RS02255
gene id: 880478:THESIDRAFT1_RS02255
uniprot id: I9KRS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS10410
gene id: 880478:THESIDRAFT1_RS10410
uniprot id: I9KVI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

880478:THESIDRAFT1 RS08605
gene id: 880478:THESIDRAFT1_RS08605
uniprot id: I9KUN0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

880478:THESIDRAFT1 RS12185
gene id: 880478:THESIDRAFT1_RS12185
uniprot id: I9KWH0
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

880478:THESIDRAFT1 RS00815
gene id: 880478:THESIDRAFT1_RS00815
uniprot id: I9AB22
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

880478:THESIDRAFT1 RS07705
gene id: 880478:THESIDRAFT1_RS07705
uniprot id: I9KU80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

880478:THESIDRAFT1 RS03525
gene id: 880478:THESIDRAFT1_RS03525
uniprot id: I8R2W6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

880478:THESIDRAFT1 RS02575
gene id: 880478:THESIDRAFT1_RS02575
uniprot id: I9KRN1
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

880478:THESIDRAFT1 RS06410
gene id: 880478:THESIDRAFT1_RS06410
uniprot id: I9KTU0
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

880478:THESIDRAFT1 RS10655
gene id: 880478:THESIDRAFT1_RS10655
uniprot id: I8R0U0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

880478:THESIDRAFT1 RS12605
gene id: 880478:THESIDRAFT1_RS12605
uniprot id: I8R763
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

880478:THESIDRAFT1 RS09275
gene id: 880478:THESIDRAFT1_RS09275
uniprot id: I8R051
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS04825
gene id: 880478:THESIDRAFT1_RS04825
uniprot id: I9AD98
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS02625
gene id: 880478:THESIDRAFT1_RS02625
uniprot id: I9KRN8
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

880478:THESIDRAFT1 RS04030
gene id: 880478:THESIDRAFT1_RS04030
uniprot id: I9KSN0
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

880478:THESIDRAFT1 RS03480
gene id: 880478:THESIDRAFT1_RS03480
uniprot id: I8QXK6
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

880478:THESIDRAFT1 RS01960
gene id: 880478:THESIDRAFT1_RS01960
uniprot id: I8R249
names: Similarity
messages: Belongs to the LacAB/RpiB family.

880478:THESIDRAFT1 RS09300
gene id: 880478:THESIDRAFT1_RS09300
uniprot id: I8R054
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

880478:THESIDRAFT1 RS03085
gene id: 880478:THESIDRAFT1_RS03085
uniprot id: I9KS58
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

880478:THESIDRAFT1 RS06010
gene id: 880478:THESIDRAFT1_RS06010
uniprot id: I9ADW0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS02075
gene id: 880478:THESIDRAFT1_RS02075
uniprot id: I8QX05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

880478:THESIDRAFT1 RS08305
gene id: 880478:THESIDRAFT1_RS08305
uniprot id: I9KUS7
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS08640
gene id: 880478:THESIDRAFT1_RS08640
uniprot id: I9KUY4
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

880478:THESIDRAFT1 RS05490
gene id: 880478:THESIDRAFT1_RS05490
uniprot id: I9ADL0
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

880478:THESIDRAFT1 RS07680
gene id: 880478:THESIDRAFT1_RS07680
uniprot id: I8QZG8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

880478:THESIDRAFT1 RS08525
gene id: 880478:THESIDRAFT1_RS08525
uniprot id: I8QZS0
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

880478:THESIDRAFT1 RS08375
gene id: 880478:THESIDRAFT1_RS08375
uniprot id: I9KUJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

880478:THESIDRAFT1 RS02840
gene id: 880478:THESIDRAFT1_RS02840
uniprot id: I8QXC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

880478:THESIDRAFT1 RS05030
gene id: 880478:THESIDRAFT1_RS05030
uniprot id: I9ADD0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

880478:THESIDRAFT1 RS03245
gene id: 880478:THESIDRAFT1_RS03245
uniprot id: I8QXI4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS12335
gene id: 880478:THESIDRAFT1_RS12335
uniprot id: I9KWM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

880478:THESIDRAFT1 RS01855
gene id: 880478:THESIDRAFT1_RS01855
uniprot id: I9KRB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

880478:THESIDRAFT1 RS11255
gene id: 880478:THESIDRAFT1_RS11255
uniprot id: I9AGN8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

880478:THESIDRAFT1 RS01680
gene id: 880478:THESIDRAFT1_RS01680
uniprot id: I8R1X0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

880478:THESIDRAFT1 RS00455
gene id: 880478:THESIDRAFT1_RS00455
uniprot id: I9KQT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

880478:THESIDRAFT1 RS06955
gene id: 880478:THESIDRAFT1_RS06955
uniprot id: I8R4N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

880478:THESIDRAFT1 RS03555
gene id: 880478:THESIDRAFT1_RS03555
uniprot id: I9KSE4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

880478:THESIDRAFT1 RS02960
gene id: 880478:THESIDRAFT1_RS02960
uniprot id: I8R2L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

880478:THESIDRAFT1 RS10595
gene id: 880478:THESIDRAFT1_RS10595
uniprot id: I9KVZ2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

880478:THESIDRAFT1 RS06060
gene id: 880478:THESIDRAFT1_RS06060
uniprot id: I9KTN8
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

880478:THESIDRAFT1 RS07895
gene id: 880478:THESIDRAFT1_RS07895
uniprot id: I8R551
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS07865
gene id: 880478:THESIDRAFT1_RS07865
uniprot id: I8R549
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

880478:THESIDRAFT1 RS06630
gene id: 880478:THESIDRAFT1_RS06630
uniprot id: I9KTX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

880478:THESIDRAFT1 RS10985
gene id: 880478:THESIDRAFT1_RS10985
uniprot id: I9KVT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

880478:THESIDRAFT1 RS08775
gene id: 880478:THESIDRAFT1_RS08775
uniprot id: I8QZW6
names: Similarity
messages: Belongs to the MreC family.

880478:THESIDRAFT1 RS06225
gene id: 880478:THESIDRAFT1_RS06225
uniprot id: I9AE00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Membrane

880478:THESIDRAFT1 RS14510
gene id: 880478:THESIDRAFT1_RS14510
uniprot id: I9ABS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS01725
gene id: 880478:THESIDRAFT1_RS01725
uniprot id: I9KR71
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS02600
gene id: 880478:THESIDRAFT1_RS02600
uniprot id: I9KRN3
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

880478:THESIDRAFT1 RS10675
gene id: 880478:THESIDRAFT1_RS10675
uniprot id: I9AGC6
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

880478:THESIDRAFT1 RS01820
gene id: 880478:THESIDRAFT1_RS01820
uniprot id: I9KRJ3
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS10680
gene id: 880478:THESIDRAFT1_RS10680
uniprot id: I8R0U4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS06240
gene id: 880478:THESIDRAFT1_RS06240
uniprot id: I8R4A7
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS03965
gene id: 880478:THESIDRAFT1_RS03965
uniprot id: I8QXS3
names: Similarity
messages: Belongs to the SfsA family.

880478:THESIDRAFT1 RS03600
gene id: 880478:THESIDRAFT1_RS03600
uniprot id: I8R2X8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

880478:THESIDRAFT1 RS00380
gene id: 880478:THESIDRAFT1_RS00380
uniprot id: I9KQR5
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

880478:THESIDRAFT1 RS03605
gene id: 880478:THESIDRAFT1_RS03605
uniprot id: I9KSF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

880478:THESIDRAFT1 RS06550
gene id: 880478:THESIDRAFT1_RS06550
uniprot id: I9KTL6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

880478:THESIDRAFT1 RS11145
gene id: 880478:THESIDRAFT1_RS11145
uniprot id: I9KW94
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

880478:THESIDRAFT1 RS03900
gene id: 880478:THESIDRAFT1_RS03900
uniprot id: I9KSA5
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

880478:THESIDRAFT1 RS03550
gene id: 880478:THESIDRAFT1_RS03550
uniprot id: I8R2X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

880478:THESIDRAFT1 RS03680
gene id: 880478:THESIDRAFT1_RS03680
uniprot id: I9KSG7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

880478:THESIDRAFT1 RS11960
gene id: 880478:THESIDRAFT1_RS11960
uniprot id: I9AH40
names: Similarity
messages: Belongs to the IMPACT family.

880478:THESIDRAFT1 RS02135
gene id: 880478:THESIDRAFT1_RS02135
uniprot id: I8R277
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

880478:THESIDRAFT1 RS08955
gene id: 880478:THESIDRAFT1_RS08955
uniprot id: I8R5K6
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS10065
gene id: 880478:THESIDRAFT1_RS10065
uniprot id: I8R0L9
names: Similarity
messages: Belongs to the TrpF family.

880478:THESIDRAFT1 RS06525
gene id: 880478:THESIDRAFT1_RS06525
uniprot id: I9KTL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

880478:THESIDRAFT1 RS03735
gene id: 880478:THESIDRAFT1_RS03735
uniprot id: I9ACM9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

880478:THESIDRAFT1 RS00150
gene id: 880478:THESIDRAFT1_RS00150
uniprot id: I9AAP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

880478:THESIDRAFT1 RS06665
gene id: 880478:THESIDRAFT1_RS06665
uniprot id: I8QYY2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS05560
gene id: 880478:THESIDRAFT1_RS05560
uniprot id: I9KTG6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

880478:THESIDRAFT1 RS01600
gene id: 880478:THESIDRAFT1_RS01600
uniprot id: I9KR45
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS11815
gene id: 880478:THESIDRAFT1_RS11815
uniprot id: I9AH08
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

880478:THESIDRAFT1 RS01525
gene id: 880478:THESIDRAFT1_RS01525
uniprot id: I9ABG8
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

880478:THESIDRAFT1 RS06895
gene id: 880478:THESIDRAFT1_RS06895
uniprot id: I8QZ27
names: Cofactor
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Binds 1 Mg(2+) ion per subunit.

880478:THESIDRAFT1 RS03625
gene id: 880478:THESIDRAFT1_RS03625
uniprot id: I8R2Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

880478:THESIDRAFT1 RS07475
gene id: 880478:THESIDRAFT1_RS07475
uniprot id: I8QZE2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS02545
gene id: 880478:THESIDRAFT1_RS02545
uniprot id: I8QX84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

880478:THESIDRAFT1 RS11800
gene id: 880478:THESIDRAFT1_RS11800
uniprot id: I9KW95
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS07000
gene id: 880478:THESIDRAFT1_RS07000
uniprot id: I8R4P3
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS02800
gene id: 880478:THESIDRAFT1_RS02800
uniprot id: I9KRR8
names: Similarity
messages: Belongs to the peptidase S41A family.

880478:THESIDRAFT1 RS03660
gene id: 880478:THESIDRAFT1_RS03660
uniprot id: I9ACL4
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

880478:THESIDRAFT1 RS02560
gene id: 880478:THESIDRAFT1_RS02560
uniprot id: I9KRX2
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

880478:THESIDRAFT1 RS02045
gene id: 880478:THESIDRAFT1_RS02045
uniprot id: I9ABR8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

880478:THESIDRAFT1 RS06180
gene id: 880478:THESIDRAFT1_RS06180
uniprot id: I9KTG7
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

880478:THESIDRAFT1 RS09665
gene id: 880478:THESIDRAFT1_RS09665
uniprot id: I9AFU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

880478:THESIDRAFT1 RS08760
gene id: 880478:THESIDRAFT1_RS08760
uniprot id: I8R5H7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

880478:THESIDRAFT1 RS04345
gene id: 880478:THESIDRAFT1_RS04345
uniprot id: I9KST4
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

880478:THESIDRAFT1 RS05905
gene id: 880478:THESIDRAFT1_RS05905
uniprot id: I9KTL5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

880478:THESIDRAFT1 RS03715
gene id: 880478:THESIDRAFT1_RS03715
uniprot id: I8QXN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

880478:THESIDRAFT1 RS03745
gene id: 880478:THESIDRAFT1_RS03745
uniprot id: I9KS76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

880478:THESIDRAFT1 RS05520
gene id: 880478:THESIDRAFT1_RS05520
uniprot id: I8QYH5
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

880478:THESIDRAFT1 RS05305
gene id: 880478:THESIDRAFT1_RS05305
uniprot id: I8R3T9
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

880478:THESIDRAFT1 RS03060
gene id: 880478:THESIDRAFT1_RS03060
uniprot id: I9KS53
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

880478:THESIDRAFT1 RS03540
gene id: 880478:THESIDRAFT1_RS03540
uniprot id: I8QXL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

880478:THESIDRAFT1 RS11445
gene id: 880478:THESIDRAFT1_RS11445
uniprot id: I8R193
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

880478:THESIDRAFT1 RS00475
gene id: 880478:THESIDRAFT1_RS00475
uniprot id: I8R1B0
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS09125
gene id: 880478:THESIDRAFT1_RS09125
uniprot id: I9KUX8
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

880478:THESIDRAFT1 RS09210
gene id: 880478:THESIDRAFT1_RS09210
uniprot id: I8R5P6
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

880478:THESIDRAFT1 RS03610
gene id: 880478:THESIDRAFT1_RS03610
uniprot id: I9ACK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

880478:THESIDRAFT1 RS00340
gene id: 880478:THESIDRAFT1_RS00340
uniprot id: I9AAS8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

880478:THESIDRAFT1 RS00480
gene id: 880478:THESIDRAFT1_RS00480
uniprot id: I9KQR5
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

880478:THESIDRAFT1 RS10700
gene id: 880478:THESIDRAFT1_RS10700
uniprot id: I9AGD1
names: Similarity
messages: Belongs to the DprA/Smf family.

880478:THESIDRAFT1 RS10335
gene id: 880478:THESIDRAFT1_RS10335
uniprot id: I8R0Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

880478:THESIDRAFT1 RS05660
gene id: 880478:THESIDRAFT1_RS05660
uniprot id: I9KTI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

880478:THESIDRAFT1 RS08095
gene id: 880478:THESIDRAFT1_RS08095
uniprot id: I9KUQ0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

880478:THESIDRAFT1 RS07885
gene id: 880478:THESIDRAFT1_RS07885
uniprot id: I8QZJ4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

880478:THESIDRAFT1 RS03750
gene id: 880478:THESIDRAFT1_RS03750
uniprot id: I8R304
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

880478:THESIDRAFT1 RS05025
gene id: 880478:THESIDRAFT1_RS05025
uniprot id: I9KT71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

880478:THESIDRAFT1 RS00345
gene id: 880478:THESIDRAFT1_RS00345
uniprot id: I8QW37
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

880478:THESIDRAFT1 RS03250
gene id: 880478:THESIDRAFT1_RS03250
uniprot id: I9KRZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

880478:THESIDRAFT1 RS11085
gene id: 880478:THESIDRAFT1_RS11085
uniprot id: I9KVV7
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

880478:THESIDRAFT1 RS08505
gene id: 880478:THESIDRAFT1_RS08505
uniprot id: I9KUL3
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

880478:THESIDRAFT1 RS00960
gene id: 880478:THESIDRAFT1_RS00960
uniprot id: I8QWC5
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

880478:THESIDRAFT1 RS08345
gene id: 880478:THESIDRAFT1_RS08345
uniprot id: I8QZP4
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

880478:THESIDRAFT1 RS11885
gene id: 880478:THESIDRAFT1_RS11885
uniprot id: I9AH24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

880478:THESIDRAFT1 RS07860
gene id: 880478:THESIDRAFT1_RS07860
uniprot id: I9KUB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

880478:THESIDRAFT1 RS09270
gene id: 880478:THESIDRAFT1_RS09270
uniprot id: I9AFL9
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS09650
gene id: 880478:THESIDRAFT1_RS09650
uniprot id: I9KV72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

880478:THESIDRAFT1 RS03130
gene id: 880478:THESIDRAFT1_RS03130
uniprot id: I8R2P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

880478:THESIDRAFT1 RS08745
gene id: 880478:THESIDRAFT1_RS08745
uniprot id: I9AFB7
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

880478:THESIDRAFT1 RS07330
gene id: 880478:THESIDRAFT1_RS07330
uniprot id: I9AEM0
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

880478:THESIDRAFT1 RS00955
gene id: 880478:THESIDRAFT1_RS00955
uniprot id: I9AB51
names: Similarity
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.

880478:THESIDRAFT1 RS12510
gene id: 880478:THESIDRAFT1_RS12510
uniprot id: I8R1Y9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

880478:THESIDRAFT1 RS05495
gene id: 880478:THESIDRAFT1_RS05495
uniprot id: I8QYH2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

880478:THESIDRAFT1 RS10385
gene id: 880478:THESIDRAFT1_RS10385
uniprot id: I9KVH6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS10060
gene id: 880478:THESIDRAFT1_RS10060
uniprot id: I9AG30
names: Similarity
messages: Belongs to the TrpC family.

880478:THESIDRAFT1 RS06740
gene id: 880478:THESIDRAFT1_RS06740
uniprot id: I8QYZ3
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

880478:THESIDRAFT1 RS10515
gene id: 880478:THESIDRAFT1_RS10515
uniprot id: I8R681
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

880478:THESIDRAFT1 RS03175
gene id: 880478:THESIDRAFT1_RS03175
uniprot id: I9KRY2
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS01105
gene id: 880478:THESIDRAFT1_RS01105
uniprot id: I9KR51
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

880478:THESIDRAFT1 RS11645
gene id: 880478:THESIDRAFT1_RS11645
uniprot id: I8R1D8
names: Similarity
messages: Belongs to the GSP E family.

880478:THESIDRAFT1 RS08090
gene id: 880478:THESIDRAFT1_RS08090
uniprot id: I8R576
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

880478:THESIDRAFT1 RS01040
gene id: 880478:THESIDRAFT1_RS01040
uniprot id: I9KQT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS01160
gene id: 880478:THESIDRAFT1_RS01160
uniprot id: I9AB95
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

880478:THESIDRAFT1 RS06680
gene id: 880478:THESIDRAFT1_RS06680
uniprot id: I9KTY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

880478:THESIDRAFT1 RS03115
gene id: 880478:THESIDRAFT1_RS03115
uniprot id: I9ACB0
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS06780
gene id: 880478:THESIDRAFT1_RS06780
uniprot id: I9KU04
names: Similarity
messages: Belongs to the HypD family.

880478:THESIDRAFT1 RS05900
gene id: 880478:THESIDRAFT1_RS05900
uniprot id: I8R446
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

880478:THESIDRAFT1 RS04905
gene id: 880478:THESIDRAFT1_RS04905
uniprot id: I8QY88
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

880478:THESIDRAFT1 RS04135
gene id: 880478:THESIDRAFT1_RS04135
uniprot id: I9KSP8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

880478:THESIDRAFT1 RS07690
gene id: 880478:THESIDRAFT1_RS07690
uniprot id: I8R530
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

880478:THESIDRAFT1 RS11025
gene id: 880478:THESIDRAFT1_RS11025
uniprot id: I9AGJ1
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

880478:THESIDRAFT1 RS03705
gene id: 880478:THESIDRAFT1_RS03705
uniprot id: I9KSH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

880478:THESIDRAFT1 RS06760
gene id: 880478:THESIDRAFT1_RS06760
uniprot id: I9AE95
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

880478:THESIDRAFT1 RS01155
gene id: 880478:THESIDRAFT1_RS01155
uniprot id: I9KR59
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

880478:THESIDRAFT1 RS03295
gene id: 880478:THESIDRAFT1_RS03295
uniprot id: I8QXJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

880478:THESIDRAFT1 RS10660
gene id: 880478:THESIDRAFT1_RS10660
uniprot id: I9KVM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

880478:THESIDRAFT1 RS07585
gene id: 880478:THESIDRAFT1_RS07585
uniprot id: I9KU61
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

880478:THESIDRAFT1 RS10035
gene id: 880478:THESIDRAFT1_RS10035
uniprot id: I9AG26
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

880478:THESIDRAFT1 RS12375
gene id: 880478:THESIDRAFT1_RS12375
uniprot id: I9AHE5
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

880478:THESIDRAFT1 RS09295
gene id: 880478:THESIDRAFT1_RS09295
uniprot id: I9AFM4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

880478:THESIDRAFT1 RS09490
gene id: 880478:THESIDRAFT1_RS09490
uniprot id: I9KVC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

880478:THESIDRAFT1 RS06050
gene id: 880478:THESIDRAFT1_RS06050
uniprot id: I9KTE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

880478:THESIDRAFT1 RS08680
gene id: 880478:THESIDRAFT1_RS08680
uniprot id: I9KUP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

880478:THESIDRAFT1 RS09015
gene id: 880478:THESIDRAFT1_RS09015
uniprot id: I9AFG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

880478:THESIDRAFT1 RS03150
gene id: 880478:THESIDRAFT1_RS03150
uniprot id: I9KRX8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

880478:THESIDRAFT1 RS05140
gene id: 880478:THESIDRAFT1_RS05140
uniprot id: I9ADE8
names: Subcellular Location Annotation
messages: Membrane

880478:THESIDRAFT1 RS07295
gene id: 880478:THESIDRAFT1_RS07295
uniprot id: I9AEL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

880478:THESIDRAFT1 RS08330
gene id: 880478:THESIDRAFT1_RS08330
uniprot id: I8R5A7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

880478:THESIDRAFT1 RS09550
gene id: 880478:THESIDRAFT1_RS09550
uniprot id: I8R0A6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880478:THESIDRAFT1 RS06245
gene id: 880478:THESIDRAFT1_RS06245
uniprot id: I9KTR5
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

880478:THESIDRAFT1 RS10545
gene id: 880478:THESIDRAFT1_RS10545
uniprot id: I9KVY1
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

880478:THESIDRAFT1 RS07290
gene id: 880478:THESIDRAFT1_RS07290
uniprot id: I9KUC5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

880478:THESIDRAFT1 RS10835
gene id: 880478:THESIDRAFT1_RS10835
uniprot id: I9KVQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

880478:THESIDRAFT1 RS11705
gene id: 880478:THESIDRAFT1_RS11705
uniprot id: I8R6R4
names: Similarity
messages: Belongs to the UPF0473 family.

880478:THESIDRAFT1 RS05895
gene id: 880478:THESIDRAFT1_RS05895
uniprot id: I9KTB8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

880478:THESIDRAFT1 RS12240
gene id: 880478:THESIDRAFT1_RS12240
uniprot id: I8R722
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspI family.
messages: Expressed only in the forespore compartment of sporulating cells.
messages: Spore core

880478:THESIDRAFT1 RS05940
gene id: 880478:THESIDRAFT1_RS05940
uniprot id: I8QYL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

880478:THESIDRAFT1 RS09590
gene id: 880478:THESIDRAFT1_RS09590
uniprot id: I9KVE2
names: Similarity
messages: Belongs to the UPF0749 family.

880478:THESIDRAFT1 RS11720
gene id: 880478:THESIDRAFT1_RS11720
uniprot id: I8R1F2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

880478:THESIDRAFT1 RS10395
gene id: 880478:THESIDRAFT1_RS10395
uniprot id: I9KVV6
names: Similarity
messages: Belongs to the YicC/YloC family.

880478:THESIDRAFT1 RS09330
gene id: 880478:THESIDRAFT1_RS09330
uniprot id: I9KV15
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

880478:THESIDRAFT1 RS06255
gene id: 880478:THESIDRAFT1_RS06255
uniprot id: I8QYR4
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

880478:THESIDRAFT1 RS05175
gene id: 880478:THESIDRAFT1_RS05175
uniprot id: I9KSY6
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

880478:THESIDRAFT1 RS05415
gene id: 880478:THESIDRAFT1_RS05415
uniprot id: I9ADJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

880478:THESIDRAFT1 RS05220
gene id: 880478:THESIDRAFT1_RS05220
uniprot id: I8QYD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

880478:THESIDRAFT1 RS03700
gene id: 880478:THESIDRAFT1_RS03700
uniprot id: I8R2Z4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

880478:THESIDRAFT1 RS05035
gene id: 880478:THESIDRAFT1_RS05035
uniprot id: I8QYA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

880478:THESIDRAFT1 RS01755
gene id: 880478:THESIDRAFT1_RS01755
uniprot id: I9KR77
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.