880071:FLELI RS02640
gene id: 880071:FLELI_RS02640
uniprot id: I4AGC8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

880071:FLELI RS20615
gene id: 880071:FLELI_RS20615
uniprot id: I4AKW9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

880071:FLELI RS00260
gene id: 880071:FLELI_RS00260
uniprot id: I4AF29
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

880071:FLELI RS19975
gene id: 880071:FLELI_RS19975
uniprot id: I4AQY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

880071:FLELI RS06820
gene id: 880071:FLELI_RS06820
uniprot id: I4AIP3
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS02290
gene id: 880071:FLELI_RS02290
uniprot id: I4AG64
names: Similarity
messages: Belongs to the Dps family.

880071:FLELI RS12480
gene id: 880071:FLELI_RS12480
uniprot id: I4ALS6
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS08660
gene id: 880071:FLELI_RS08660
uniprot id: I4AJN5
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

880071:FLELI RS07405
gene id: 880071:FLELI_RS07405
uniprot id: I4AJ03
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

880071:FLELI RS17405
gene id: 880071:FLELI_RS17405
uniprot id: I4APH8
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

880071:FLELI RS14595
gene id: 880071:FLELI_RS14595
uniprot id: I4AMY3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

880071:FLELI RS15190
gene id: 880071:FLELI_RS15190
uniprot id: I4ANA0
names: Function
names: Similarity
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.

880071:FLELI RS06275
gene id: 880071:FLELI_RS06275
uniprot id: I4AID6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS07555
gene id: 880071:FLELI_RS07555
uniprot id: I4AJ33
names: Similarity
messages: Belongs to the Skp family.

880071:FLELI RS15705
gene id: 880071:FLELI_RS15705
uniprot id: I4ANJ3
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

880071:FLELI RS18440
gene id: 880071:FLELI_RS18440
uniprot id: I4AQ32
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

880071:FLELI RS12585
gene id: 880071:FLELI_RS12585
uniprot id: I4ALU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

880071:FLELI RS01845
gene id: 880071:FLELI_RS01845
uniprot id: I4AFX2
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

880071:FLELI RS15440
gene id: 880071:FLELI_RS15440
uniprot id: I4ANE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

880071:FLELI RS09750
gene id: 880071:FLELI_RS09750
uniprot id: I4AK89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

880071:FLELI RS14610
gene id: 880071:FLELI_RS14610
uniprot id: I4AMY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

880071:FLELI RS06575
gene id: 880071:FLELI_RS06575
uniprot id: I4AIJ4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

880071:FLELI RS03635
gene id: 880071:FLELI_RS03635
uniprot id: I4AGX4
names: Similarity
messages: Belongs to the peptidase S13 family.

880071:FLELI RS03955
gene id: 880071:FLELI_RS03955
uniprot id: I4AH40
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

880071:FLELI RS05765
gene id: 880071:FLELI_RS05765
uniprot id: I4AI36
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

880071:FLELI RS16605
gene id: 880071:FLELI_RS16605
uniprot id: I4AP19
names: Similarity
messages: Belongs to the peptidase M17 family.

880071:FLELI RS14280
gene id: 880071:FLELI_RS14280
uniprot id: I4AMS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

880071:FLELI RS13315
gene id: 880071:FLELI_RS13315
uniprot id: I4AM88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

880071:FLELI RS07730
gene id: 880071:FLELI_RS07730
uniprot id: I4AJ66
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

880071:FLELI RS02965
gene id: 880071:FLELI_RS02965
uniprot id: I4AGJ1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

880071:FLELI RS16345
gene id: 880071:FLELI_RS16345
uniprot id: I4ANX2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS00645
gene id: 880071:FLELI_RS00645
uniprot id: I4AF96
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

880071:FLELI RS06760
gene id: 880071:FLELI_RS06760
uniprot id: I4AIN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

880071:FLELI RS17750
gene id: 880071:FLELI_RS17750
uniprot id: I4APP6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS07270
gene id: 880071:FLELI_RS07270
uniprot id: I4AIX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

880071:FLELI RS07200
gene id: 880071:FLELI_RS07200
uniprot id: I4AIW5
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS03315
gene id: 880071:FLELI_RS03315
uniprot id: I4AGR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

880071:FLELI RS05780
gene id: 880071:FLELI_RS05780
uniprot id: I4AI39
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

880071:FLELI RS13225
gene id: 880071:FLELI_RS13225
uniprot id: I4AM69
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

880071:FLELI RS12210
gene id: 880071:FLELI_RS12210
uniprot id: I4ALL9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

880071:FLELI RS12215
gene id: 880071:FLELI_RS12215
uniprot id: I4ALM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

880071:FLELI RS12620
gene id: 880071:FLELI_RS12620
uniprot id: I4ALV4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

880071:FLELI RS16835
gene id: 880071:FLELI_RS16835
uniprot id: I4AP63
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

880071:FLELI RS04675
gene id: 880071:FLELI_RS04675
uniprot id: I4AHI2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

880071:FLELI RS13280
gene id: 880071:FLELI_RS13280
uniprot id: I4AM80
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS18150
gene id: 880071:FLELI_RS18150
uniprot id: I4APX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

880071:FLELI RS05220
gene id: 880071:FLELI_RS05220
uniprot id: I4AHS5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS14850
gene id: 880071:FLELI_RS14850
uniprot id: I4AN31
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

880071:FLELI RS18200
gene id: 880071:FLELI_RS18200
uniprot id: I4APY3
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

880071:FLELI RS12120
gene id: 880071:FLELI_RS12120
uniprot id: I4ALK1
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS01015
gene id: 880071:FLELI_RS01015
uniprot id: I4AFG6
names: Similarity
messages: Belongs to the IMPACT family.

880071:FLELI RS18520
gene id: 880071:FLELI_RS18520
uniprot id: I4AQ49
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

880071:FLELI RS02430
gene id: 880071:FLELI_RS02430
uniprot id: I4AG93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

880071:FLELI RS11780
gene id: 880071:FLELI_RS11780
uniprot id: I4ALD4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

880071:FLELI RS04130
gene id: 880071:FLELI_RS04130
uniprot id: I4AH75
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

880071:FLELI RS07985
gene id: 880071:FLELI_RS07985
uniprot id: I4AJB6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

880071:FLELI RS15065
gene id: 880071:FLELI_RS15065
uniprot id: I4AN75
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS08330
gene id: 880071:FLELI_RS08330
uniprot id: I4AJI0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

880071:FLELI RS06360
gene id: 880071:FLELI_RS06360
uniprot id: I4AIF1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

880071:FLELI RS18190
gene id: 880071:FLELI_RS18190
uniprot id: I4APY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

880071:FLELI RS20560
gene id: 880071:FLELI_RS20560
uniprot id: I4AK26
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS06685
gene id: 880071:FLELI_RS06685
uniprot id: I4AIL6
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS07655
gene id: 880071:FLELI_RS07655
uniprot id: I4AJ51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

880071:FLELI RS19850
gene id: 880071:FLELI_RS19850
uniprot id: I4AQV5
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

880071:FLELI RS05730
gene id: 880071:FLELI_RS05730
uniprot id: I4AI29
names: Subcellular Location Annotation
messages: Cytoplasm

880071:FLELI RS04310
gene id: 880071:FLELI_RS04310
uniprot id: I4AHA9
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

880071:FLELI RS18970
gene id: 880071:FLELI_RS18970
uniprot id: I4AQD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

880071:FLELI RS17620
gene id: 880071:FLELI_RS17620
uniprot id: I4APM2
names: Similarity
messages: Belongs to the DEAD box helicase family.

880071:FLELI RS22225
gene id: 880071:FLELI_RS22225
uniprot id: I4AG54
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS12510
gene id: 880071:FLELI_RS12510
uniprot id: I4ALT1
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS04355
gene id: 880071:FLELI_RS04355
uniprot id: I4AHB7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

880071:FLELI RS01040
gene id: 880071:FLELI_RS01040
uniprot id: I4AFH1
names: Similarity
messages: Belongs to the SAICAR synthetase family.

880071:FLELI RS02810
gene id: 880071:FLELI_RS02810
uniprot id: I4AGG3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

880071:FLELI RS05300
gene id: 880071:FLELI_RS05300
uniprot id: I4AHU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

880071:FLELI RS11405
gene id: 880071:FLELI_RS11405
uniprot id: I4AL65
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS10910
gene id: 880071:FLELI_RS10910
uniprot id: I4AKW8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

880071:FLELI RS11370
gene id: 880071:FLELI_RS11370
uniprot id: I4AL58
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

880071:FLELI RS19225
gene id: 880071:FLELI_RS19225
uniprot id: I4AQI2
names: Similarity
messages: Belongs to the AlaDH/PNT family.

880071:FLELI RS06935
gene id: 880071:FLELI_RS06935
uniprot id: I4AIR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

880071:FLELI RS06865
gene id: 880071:FLELI_RS06865
uniprot id: I4AIQ1
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

880071:FLELI RS17550
gene id: 880071:FLELI_RS17550
uniprot id: I4APK8
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS06110
gene id: 880071:FLELI_RS06110
uniprot id: I4AIA4
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS18290
gene id: 880071:FLELI_RS18290
uniprot id: I4AQ02
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

880071:FLELI RS01825
gene id: 880071:FLELI_RS01825
uniprot id: I4AFW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

880071:FLELI RS04125
gene id: 880071:FLELI_RS04125
uniprot id: I4AH74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

880071:FLELI RS11835
gene id: 880071:FLELI_RS11835
uniprot id: I4ALE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

880071:FLELI RS14325
gene id: 880071:FLELI_RS14325
uniprot id: I4AMT3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

880071:FLELI RS06695
gene id: 880071:FLELI_RS06695
uniprot id: I4AIL8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

880071:FLELI RS09475
gene id: 880071:FLELI_RS09475
uniprot id: I4AK36
names: Similarity
messages: Belongs to the UPF0102 family.

880071:FLELI RS18285
gene id: 880071:FLELI_RS18285
uniprot id: I4AQ01
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS16580
gene id: 880071:FLELI_RS16580
uniprot id: I4AP14
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

880071:FLELI RS19110
gene id: 880071:FLELI_RS19110
uniprot id: I4AQF9
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

880071:FLELI RS12640
gene id: 880071:FLELI_RS12640
uniprot id: I4ALV8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

880071:FLELI RS04615
gene id: 880071:FLELI_RS04615
uniprot id: I4AHH2
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

880071:FLELI RS12575
gene id: 880071:FLELI_RS12575
uniprot id: I4ALU5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

880071:FLELI RS01520
gene id: 880071:FLELI_RS01520
uniprot id: I4AFR1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

880071:FLELI RS12975
gene id: 880071:FLELI_RS12975
uniprot id: I4AM22
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

880071:FLELI RS00530
gene id: 880071:FLELI_RS00530
uniprot id: I4AF75
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

880071:FLELI RS06705
gene id: 880071:FLELI_RS06705
uniprot id: I4AIL9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

880071:FLELI RS00550
gene id: 880071:FLELI_RS00550
uniprot id: I4AF79
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

880071:FLELI RS13055
gene id: 880071:FLELI_RS13055
uniprot id: I4AM36
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

880071:FLELI RS06145
gene id: 880071:FLELI_RS06145
uniprot id: I4AIB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

880071:FLELI RS12905
gene id: 880071:FLELI_RS12905
uniprot id: I4AM10
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

880071:FLELI RS07990
gene id: 880071:FLELI_RS07990
uniprot id: I4AJB7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

880071:FLELI RS18050
gene id: 880071:FLELI_RS18050
uniprot id: I4APV4
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS14920
gene id: 880071:FLELI_RS14920
uniprot id: I4AN46
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

880071:FLELI RS04305
gene id: 880071:FLELI_RS04305
uniprot id: I4AHA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

880071:FLELI RS08540
gene id: 880071:FLELI_RS08540
uniprot id: I4AJL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell inner membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

880071:FLELI RS03130
gene id: 880071:FLELI_RS03130
uniprot id: I4AGM4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

880071:FLELI RS08065
gene id: 880071:FLELI_RS08065
uniprot id: I4AJC9
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS11975
gene id: 880071:FLELI_RS11975
uniprot id: I4ALH4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

880071:FLELI RS04165
gene id: 880071:FLELI_RS04165
uniprot id: I4AH81
names: Similarity
messages: Belongs to the thioredoxin family.

880071:FLELI RS05625
gene id: 880071:FLELI_RS05625
uniprot id: I4AI07
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

880071:FLELI RS16960
gene id: 880071:FLELI_RS16960
uniprot id: I4AP88
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

880071:FLELI RS10815
gene id: 880071:FLELI_RS10815
uniprot id: I4AKV1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

880071:FLELI RS10235
gene id: 880071:FLELI_RS10235
uniprot id: I4AKI6
names: Similarity
messages: Belongs to the Nth/MutY family.

880071:FLELI RS02295
gene id: 880071:FLELI_RS02295
uniprot id: I4AG65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

880071:FLELI RS19600
gene id: 880071:FLELI_RS19600
uniprot id: I4AQQ9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

880071:FLELI RS16810
gene id: 880071:FLELI_RS16810
uniprot id: I4AP58
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

880071:FLELI RS00035
gene id: 880071:FLELI_RS00035
uniprot id: I4AEY4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

880071:FLELI RS18745
gene id: 880071:FLELI_RS18745
uniprot id: I4AQ87
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

880071:FLELI RS02050
gene id: 880071:FLELI_RS02050
uniprot id: I4AG14
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

880071:FLELI RS03890
gene id: 880071:FLELI_RS03890
uniprot id: I4AH28
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS17415
gene id: 880071:FLELI_RS17415
uniprot id: I4API0
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS18155
gene id: 880071:FLELI_RS18155
uniprot id: I4APX5
names: Similarity
messages: Belongs to the TrpF family.

880071:FLELI RS02775
gene id: 880071:FLELI_RS02775
uniprot id: I4AGF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

880071:FLELI RS18555
gene id: 880071:FLELI_RS18555
uniprot id: I4AQ55
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

880071:FLELI RS10575
gene id: 880071:FLELI_RS10575
uniprot id: I4AKQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

880071:FLELI RS10200
gene id: 880071:FLELI_RS10200
uniprot id: I4AKH9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

880071:FLELI RS07400
gene id: 880071:FLELI_RS07400
uniprot id: I4AJ02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

880071:FLELI RS00500
gene id: 880071:FLELI_RS00500
uniprot id: I4AF71
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS13760
gene id: 880071:FLELI_RS13760
uniprot id: I4AMH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

880071:FLELI RS20440
gene id: 880071:FLELI_RS20440
uniprot id: I4AIT0
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

880071:FLELI RS09625
gene id: 880071:FLELI_RS09625
uniprot id: I4AK64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

880071:FLELI RS17220
gene id: 880071:FLELI_RS17220
uniprot id: I4APE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

880071:FLELI RS04475
gene id: 880071:FLELI_RS04475
uniprot id: I4AHE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

880071:FLELI RS15180
gene id: 880071:FLELI_RS15180
uniprot id: I4AN98
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS12230
gene id: 880071:FLELI_RS12230
uniprot id: I4ALM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Mitochondrion

880071:FLELI RS20725
gene id: 880071:FLELI_RS20725
uniprot id: I4AML2
names: Subcellular Location Annotation
messages: Cytoplasm

880071:FLELI RS07795
gene id: 880071:FLELI_RS07795
uniprot id: I4AJ79
names: Similarity
messages: Belongs to the methyltransferase superfamily. PrmA family.

880071:FLELI RS03625
gene id: 880071:FLELI_RS03625
uniprot id: I4AGX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

880071:FLELI RS02715
gene id: 880071:FLELI_RS02715
uniprot id: I4AGE3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

880071:FLELI RS07365
gene id: 880071:FLELI_RS07365
uniprot id: I4AIZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

880071:FLELI RS16900
gene id: 880071:FLELI_RS16900
uniprot id: I4AP76
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

880071:FLELI RS02180
gene id: 880071:FLELI_RS02180
uniprot id: I4AG41
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS07625
gene id: 880071:FLELI_RS07625
uniprot id: I4AJ45
names: Similarity
messages: Belongs to the asparagine synthetase family.

880071:FLELI RS00465
gene id: 880071:FLELI_RS00465
uniprot id: I4AF66
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS03430
gene id: 880071:FLELI_RS03430
uniprot id: I4AGT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

880071:FLELI RS07190
gene id: 880071:FLELI_RS07190
uniprot id: I4AIW3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS09360
gene id: 880071:FLELI_RS09360
uniprot id: I4AK15
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

880071:FLELI RS04945
gene id: 880071:FLELI_RS04945
uniprot id: I4AHN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

880071:FLELI RS15620
gene id: 880071:FLELI_RS15620
uniprot id: I4ANH6
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

880071:FLELI RS07540
gene id: 880071:FLELI_RS07540
uniprot id: I4AJ30
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

880071:FLELI RS04905
gene id: 880071:FLELI_RS04905
uniprot id: I4AHM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

880071:FLELI RS08165
gene id: 880071:FLELI_RS08165
uniprot id: I4AJE9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

880071:FLELI RS11965
gene id: 880071:FLELI_RS11965
uniprot id: I4ALH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

880071:FLELI RS06560
gene id: 880071:FLELI_RS06560
uniprot id: I4AIJ1
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS17655
gene id: 880071:FLELI_RS17655
uniprot id: I4APM8
names: Similarity
messages: Belongs to the sterol desaturase family.

880071:FLELI RS17390
gene id: 880071:FLELI_RS17390
uniprot id: I4APH5
names: Similarity
messages: Belongs to the polysaccharide synthase family.

880071:FLELI RS12550
gene id: 880071:FLELI_RS12550
uniprot id: I4ALU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

880071:FLELI RS19520
gene id: 880071:FLELI_RS19520
uniprot id: I4AQP3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS12475
gene id: 880071:FLELI_RS12475
uniprot id: I4ALS5
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

880071:FLELI RS14695
gene id: 880071:FLELI_RS14695
uniprot id: I4AN02
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

880071:FLELI RS05805
gene id: 880071:FLELI_RS05805
uniprot id: I4AI44
names: Similarity
messages: Belongs to the ABC transporter superfamily.

880071:FLELI RS11425
gene id: 880071:FLELI_RS11425
uniprot id: I4AL69
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

880071:FLELI RS02850
gene id: 880071:FLELI_RS02850
uniprot id: I4AGH1
names: Function
messages: Might have a role analogous to that of eukaryotic histone proteins.

880071:FLELI RS13920
gene id: 880071:FLELI_RS13920
uniprot id: I4AMK9
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

880071:FLELI RS05900
gene id: 880071:FLELI_RS05900
uniprot id: I4AI63
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

880071:FLELI RS14265
gene id: 880071:FLELI_RS14265
uniprot id: I4AMS2
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

880071:FLELI RS15520
gene id: 880071:FLELI_RS15520
uniprot id: I4ANG1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

880071:FLELI RS16265
gene id: 880071:FLELI_RS16265
uniprot id: I4ANV6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS10240
gene id: 880071:FLELI_RS10240
uniprot id: I4AKI7
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

880071:FLELI RS09045
gene id: 880071:FLELI_RS09045
uniprot id: I4AJW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

880071:FLELI RS19695
gene id: 880071:FLELI_RS19695
uniprot id: I4AQS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

880071:FLELI RS05360
gene id: 880071:FLELI_RS05360
uniprot id: I4AHV4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

880071:FLELI RS07450
gene id: 880071:FLELI_RS07450
uniprot id: I4AJ13
names: Similarity
messages: Belongs to the CarB family.

880071:FLELI RS14725
gene id: 880071:FLELI_RS14725
uniprot id: I4AN08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

880071:FLELI RS15150
gene id: 880071:FLELI_RS15150
uniprot id: I4AN92
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

880071:FLELI RS19410
gene id: 880071:FLELI_RS19410
uniprot id: I4AQM1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

880071:FLELI RS19965
gene id: 880071:FLELI_RS19965
uniprot id: I4AQX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

880071:FLELI RS07530
gene id: 880071:FLELI_RS07530
uniprot id: I4AJ28
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

880071:FLELI RS08135
gene id: 880071:FLELI_RS08135
uniprot id: I4AJE3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

880071:FLELI RS10255
gene id: 880071:FLELI_RS10255
uniprot id: I4AKJ0
names: Similarity
messages: Belongs to the NDK family.

880071:FLELI RS20025
gene id: 880071:FLELI_RS20025
uniprot id: I4AQZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

880071:FLELI RS02130
gene id: 880071:FLELI_RS02130
uniprot id: I4AG31
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

880071:FLELI RS06965
gene id: 880071:FLELI_RS06965
uniprot id: I4AIS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

880071:FLELI RS12590
gene id: 880071:FLELI_RS12590
uniprot id: I4ALU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

880071:FLELI RS20080
gene id: 880071:FLELI_RS20080
uniprot id: I4AR00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

880071:FLELI RS00250
gene id: 880071:FLELI_RS00250
uniprot id: I4AF27
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

880071:FLELI RS20570
gene id: 880071:FLELI_RS20570
uniprot id: I4AK48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

880071:FLELI RS14735
gene id: 880071:FLELI_RS14735
uniprot id: I4AN10
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS14925
gene id: 880071:FLELI_RS14925
uniprot id: I4AN47
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

880071:FLELI RS01130
gene id: 880071:FLELI_RS01130
uniprot id: I4AFI9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

880071:FLELI RS18585
gene id: 880071:FLELI_RS18585
uniprot id: I4AQ61
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

880071:FLELI RS09860
gene id: 880071:FLELI_RS09860
uniprot id: I4AKB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

880071:FLELI RS11730
gene id: 880071:FLELI_RS11730
uniprot id: I4ALC5
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

880071:FLELI RS14225
gene id: 880071:FLELI_RS14225
uniprot id: I4AMR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

880071:FLELI RS05140
gene id: 880071:FLELI_RS05140
uniprot id: U3GJK1
names: Similarity
messages: Belongs to the SCO1/2 family.

880071:FLELI RS18805
gene id: 880071:FLELI_RS18805
uniprot id: I4AQ99
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS04215
gene id: 880071:FLELI_RS04215
uniprot id: I4AH91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

880071:FLELI RS12015
gene id: 880071:FLELI_RS12015
uniprot id: I4ALI3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

880071:FLELI RS10115
gene id: 880071:FLELI_RS10115
uniprot id: I4AKG2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

880071:FLELI RS04745
gene id: 880071:FLELI_RS04745
uniprot id: I4AHJ3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

880071:FLELI RS15785
gene id: 880071:FLELI_RS15785
uniprot id: I4ANK9
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

880071:FLELI RS09440
gene id: 880071:FLELI_RS09440
uniprot id: I4AK31
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

880071:FLELI RS06670
gene id: 880071:FLELI_RS06670
uniprot id: I4AIL3
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

880071:FLELI RS05400
gene id: 880071:FLELI_RS05400
uniprot id: I4AHW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

880071:FLELI RS11985
gene id: 880071:FLELI_RS11985
uniprot id: I4ALH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

880071:FLELI RS11200
gene id: 880071:FLELI_RS11200
uniprot id: I4AL24
names: Similarity
messages: Belongs to the AlaDH/PNT family.

880071:FLELI RS07310
gene id: 880071:FLELI_RS07310
uniprot id: I4AIY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

880071:FLELI RS12615
gene id: 880071:FLELI_RS12615
uniprot id: I4ALV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

880071:FLELI RS01525
gene id: 880071:FLELI_RS01525
uniprot id: I4AFR2
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

880071:FLELI RS16870
gene id: 880071:FLELI_RS16870
uniprot id: I4AP70
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

880071:FLELI RS03505
gene id: 880071:FLELI_RS03505
uniprot id: I4AGU8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

880071:FLELI RS16090
gene id: 880071:FLELI_RS16090
uniprot id: I4ANS1
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

880071:FLELI RS09830
gene id: 880071:FLELI_RS09830
uniprot id: I4AKA5
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

880071:FLELI RS07735
gene id: 880071:FLELI_RS07735
uniprot id: I4AJ67
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

880071:FLELI RS01775
gene id: 880071:FLELI_RS01775
uniprot id: I4AFV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

880071:FLELI RS05745
gene id: 880071:FLELI_RS05745
uniprot id: I4AI32
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS18355
gene id: 880071:FLELI_RS18355
uniprot id: I4AQ15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

880071:FLELI RS14985
gene id: 880071:FLELI_RS14985
uniprot id: I4AN59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

880071:FLELI RS06825
gene id: 880071:FLELI_RS06825
uniprot id: I4AIP4
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS14360
gene id: 880071:FLELI_RS14360
uniprot id: I4AMU0
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS07435
gene id: 880071:FLELI_RS07435
uniprot id: I4AJ09
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

880071:FLELI RS18400
gene id: 880071:FLELI_RS18400
uniprot id: I4AQ24
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

880071:FLELI RS01155
gene id: 880071:FLELI_RS01155
uniprot id: I4AFJ4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

880071:FLELI RS12600
gene id: 880071:FLELI_RS12600
uniprot id: I4ALV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

880071:FLELI RS13625
gene id: 880071:FLELI_RS13625
uniprot id: I4AMF0
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

880071:FLELI RS02660
gene id: 880071:FLELI_RS02660
uniprot id: I4AGD2
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

880071:FLELI RS02985
gene id: 880071:FLELI_RS02985
uniprot id: I4AGJ5
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS17020
gene id: 880071:FLELI_RS17020
uniprot id: I4APA1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

880071:FLELI RS02030
gene id: 880071:FLELI_RS02030
uniprot id: I4AG10
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

880071:FLELI RS17860
gene id: 880071:FLELI_RS17860
uniprot id: I4APR7
names: Caution
names: Function
names: Similarity
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).

880071:FLELI RS05060
gene id: 880071:FLELI_RS05060
uniprot id: I4AHQ1
names: Similarity
messages: Belongs to the SusD family.

880071:FLELI RS14685
gene id: 880071:FLELI_RS14685
uniprot id: I4AN00
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS16860
gene id: 880071:FLELI_RS16860
uniprot id: I4AP68
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS16275
gene id: 880071:FLELI_RS16275
uniprot id: I4ANV8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

880071:FLELI RS02805
gene id: 880071:FLELI_RS02805
uniprot id: I4AGG2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell inner membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

880071:FLELI RS03050
gene id: 880071:FLELI_RS03050
uniprot id: I4AGK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

880071:FLELI RS14905
gene id: 880071:FLELI_RS14905
uniprot id: I4AN43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

880071:FLELI RS05330
gene id: 880071:FLELI_RS05330
uniprot id: I4AHU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

880071:FLELI RS13480
gene id: 880071:FLELI_RS13480
uniprot id: I4AMC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

880071:FLELI RS15885
gene id: 880071:FLELI_RS15885
uniprot id: I4ANN0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

880071:FLELI RS17590
gene id: 880071:FLELI_RS17590
uniprot id: I4APL6
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

880071:FLELI RS12310
gene id: 880071:FLELI_RS12310
uniprot id: I4ALP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

880071:FLELI RS19010
gene id: 880071:FLELI_RS19010
uniprot id: I4AQD9
names: Similarity
messages: Belongs to the universal stress protein A family.

880071:FLELI RS04030
gene id: 880071:FLELI_RS04030
uniprot id: I4AH55
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

880071:FLELI RS16950
gene id: 880071:FLELI_RS16950
uniprot id: I4AP86
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

880071:FLELI RS05800
gene id: 880071:FLELI_RS05800
uniprot id: I4AI43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

880071:FLELI RS09620
gene id: 880071:FLELI_RS09620
uniprot id: I4AK63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

880071:FLELI RS15210
gene id: 880071:FLELI_RS15210
uniprot id: I4ANA4
names: Similarity
messages: Belongs to the peptidase S8 family.

880071:FLELI RS06200
gene id: 880071:FLELI_RS06200
uniprot id: I4AIC0
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS12515
gene id: 880071:FLELI_RS12515
uniprot id: I4ALT2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

880071:FLELI RS13420
gene id: 880071:FLELI_RS13420
uniprot id: I4AMA9
names: Similarity
messages: Belongs to the UPF0145 family.

880071:FLELI RS01495
gene id: 880071:FLELI_RS01495
uniprot id: I4AFQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Membrane

880071:FLELI RS11225
gene id: 880071:FLELI_RS11225
uniprot id: I4AL30
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

880071:FLELI RS14175
gene id: 880071:FLELI_RS14175
uniprot id: I4AMQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

880071:FLELI RS05195
gene id: 880071:FLELI_RS05195
uniprot id: I4AHS0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS07110
gene id: 880071:FLELI_RS07110
uniprot id: I4AIU9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

880071:FLELI RS20595
gene id: 880071:FLELI_RS20595
uniprot id: I4AKJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

880071:FLELI RS02750
gene id: 880071:FLELI_RS02750
uniprot id: I4AGF1
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS13320
gene id: 880071:FLELI_RS13320
uniprot id: I4AM89
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

880071:FLELI RS03900
gene id: 880071:FLELI_RS03900
uniprot id: I4AH30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

880071:FLELI RS03615
gene id: 880071:FLELI_RS03615
uniprot id: I4AGX0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

880071:FLELI RS00540
gene id: 880071:FLELI_RS00540
uniprot id: I4AF77
names: Similarity
messages: Belongs to the threonine aldolase family.

880071:FLELI RS19555
gene id: 880071:FLELI_RS19555
uniprot id: I4AQQ0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS10330
gene id: 880071:FLELI_RS10330
uniprot id: I4AKK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

880071:FLELI RS03280
gene id: 880071:FLELI_RS03280
uniprot id: I4AGQ6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

880071:FLELI RS16915
gene id: 880071:FLELI_RS16915
uniprot id: I4AP79
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

880071:FLELI RS03915
gene id: 880071:FLELI_RS03915
uniprot id: I4AH33
names: Similarity
messages: Belongs to the histone deacetylase family.

880071:FLELI RS12525
gene id: 880071:FLELI_RS12525
uniprot id: I4ALT5
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

880071:FLELI RS13510
gene id: 880071:FLELI_RS13510
uniprot id: I4AMC7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

880071:FLELI RS15775
gene id: 880071:FLELI_RS15775
uniprot id: I4ANK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

880071:FLELI RS14780
gene id: 880071:FLELI_RS14780
uniprot id: I4AN17
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS14365
gene id: 880071:FLELI_RS14365
uniprot id: I4AMU1
names: Subunit
messages: Homodimer.

880071:FLELI RS11930
gene id: 880071:FLELI_RS11930
uniprot id: I4ALG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

880071:FLELI RS17205
gene id: 880071:FLELI_RS17205
uniprot id: I4APD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

880071:FLELI RS10315
gene id: 880071:FLELI_RS10315
uniprot id: I4AKK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

880071:FLELI RS01760
gene id: 880071:FLELI_RS01760
uniprot id: I4AFV5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

880071:FLELI RS08445
gene id: 880071:FLELI_RS08445
uniprot id: I4AJJ2
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

880071:FLELI RS01755
gene id: 880071:FLELI_RS01755
uniprot id: I4AFV4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

880071:FLELI RS21295
gene id: 880071:FLELI_RS21295
uniprot id: I4AN42
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

880071:FLELI RS19015
gene id: 880071:FLELI_RS19015
uniprot id: I4AQE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

880071:FLELI RS08690
gene id: 880071:FLELI_RS08690
uniprot id: I4AJP1
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

880071:FLELI RS01835
gene id: 880071:FLELI_RS01835
uniprot id: I4AFX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

880071:FLELI RS02710
gene id: 880071:FLELI_RS02710
uniprot id: I4AGE2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

880071:FLELI RS16965
gene id: 880071:FLELI_RS16965
uniprot id: I4AP89
names: Similarity
messages: Belongs to the glutamine synthetase family.

880071:FLELI RS01515
gene id: 880071:FLELI_RS01515
uniprot id: I4AFR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

880071:FLELI RS03535
gene id: 880071:FLELI_RS03535
uniprot id: I4AGV4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS07275
gene id: 880071:FLELI_RS07275
uniprot id: I4AIX9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

880071:FLELI RS04500
gene id: 880071:FLELI_RS04500
uniprot id: I4AHE7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

880071:FLELI RS05250
gene id: 880071:FLELI_RS05250
uniprot id: I4AHT2
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

880071:FLELI RS12635
gene id: 880071:FLELI_RS12635
uniprot id: I4ALV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

880071:FLELI RS04085
gene id: 880071:FLELI_RS04085
uniprot id: I4AH66
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

880071:FLELI RS05375
gene id: 880071:FLELI_RS05375
uniprot id: I4AHV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

880071:FLELI RS10320
gene id: 880071:FLELI_RS10320
uniprot id: I4AKK3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

880071:FLELI RS15485
gene id: 880071:FLELI_RS15485
uniprot id: I4ANF4
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

880071:FLELI RS10100
gene id: 880071:FLELI_RS10100
uniprot id: I4AKF9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

880071:FLELI RS04750
gene id: 880071:FLELI_RS04750
uniprot id: I4AHJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

880071:FLELI RS06595
gene id: 880071:FLELI_RS06595
uniprot id: I4AIJ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

880071:FLELI RS08715
gene id: 880071:FLELI_RS08715
uniprot id: I4AJP6
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS02910
gene id: 880071:FLELI_RS02910
uniprot id: I4AGI0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

880071:FLELI RS12570
gene id: 880071:FLELI_RS12570
uniprot id: I4ALU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

880071:FLELI RS02680
gene id: 880071:FLELI_RS02680
uniprot id: I4AGD6
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

880071:FLELI RS10270
gene id: 880071:FLELI_RS10270
uniprot id: I4AKJ3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

880071:FLELI RS06845
gene id: 880071:FLELI_RS06845
uniprot id: I4AIP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

880071:FLELI RS03620
gene id: 880071:FLELI_RS03620
uniprot id: I4AGX1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

880071:FLELI RS04315
gene id: 880071:FLELI_RS04315
uniprot id: I4AHB0
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

880071:FLELI RS15730
gene id: 880071:FLELI_RS15730
uniprot id: I4ANJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

880071:FLELI RS17190
gene id: 880071:FLELI_RS17190
uniprot id: I4APD6
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

880071:FLELI RS11205
gene id: 880071:FLELI_RS11205
uniprot id: I4AL25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

880071:FLELI RS18995
gene id: 880071:FLELI_RS18995
uniprot id: I4AQD6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

880071:FLELI RS01225
gene id: 880071:FLELI_RS01225
uniprot id: I4AFK2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

880071:FLELI RS01250
gene id: 880071:FLELI_RS01250
uniprot id: I4AL65
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS04250
gene id: 880071:FLELI_RS04250
uniprot id: I4AH97
names: Similarity
messages: Belongs to the peptidase S8 family.

880071:FLELI RS02605
gene id: 880071:FLELI_RS02605
uniprot id: I4AGC1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

880071:FLELI RS03655
gene id: 880071:FLELI_RS03655
uniprot id: I4AGX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

880071:FLELI RS17140
gene id: 880071:FLELI_RS17140
uniprot id: I4APC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

880071:FLELI RS17235
gene id: 880071:FLELI_RS17235
uniprot id: I4APE5
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

880071:FLELI RS03780
gene id: 880071:FLELI_RS03780
uniprot id: I4AH04
names: Similarity
messages: Belongs to the GbsR family.

880071:FLELI RS10325
gene id: 880071:FLELI_RS10325
uniprot id: I4AKK4
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

880071:FLELI RS11990
gene id: 880071:FLELI_RS11990
uniprot id: I4ALH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

880071:FLELI RS06265
gene id: 880071:FLELI_RS06265
uniprot id: I4AID3
names: Similarity
messages: Belongs to the peptidase S41A family.

880071:FLELI RS11420
gene id: 880071:FLELI_RS11420
uniprot id: I4AL68
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

880071:FLELI RS18905
gene id: 880071:FLELI_RS18905
uniprot id: I4AQB8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

880071:FLELI RS07930
gene id: 880071:FLELI_RS07930
uniprot id: I4AJA4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

880071:FLELI RS07815
gene id: 880071:FLELI_RS07815
uniprot id: I4AJ83
names: Similarity
messages: Belongs to the CinA family.

880071:FLELI RS02845
gene id: 880071:FLELI_RS02845
uniprot id: I4AGH0
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

880071:FLELI RS16220
gene id: 880071:FLELI_RS16220
uniprot id: I4ANU8
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS04600
gene id: 880071:FLELI_RS04600
uniprot id: I4AHG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

880071:FLELI RS02040
gene id: 880071:FLELI_RS02040
uniprot id: I4AG12
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS02435
gene id: 880071:FLELI_RS02435
uniprot id: I4AG94
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS06835
gene id: 880071:FLELI_RS06835
uniprot id: I4AIP6
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

880071:FLELI RS02305
gene id: 880071:FLELI_RS02305
uniprot id: I4AG67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

880071:FLELI RS02120
gene id: 880071:FLELI_RS02120
uniprot id: I4AG29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

880071:FLELI RS16715
gene id: 880071:FLELI_RS16715
uniprot id: I4AP40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

880071:FLELI RS07780
gene id: 880071:FLELI_RS07780
uniprot id: I4AJ76
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

880071:FLELI RS10010
gene id: 880071:FLELI_RS10010
uniprot id: I4AKE1
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS19870
gene id: 880071:FLELI_RS19870
uniprot id: I4AQV9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

880071:FLELI RS17300
gene id: 880071:FLELI_RS17300
uniprot id: I4APF8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

880071:FLELI RS02300
gene id: 880071:FLELI_RS02300
uniprot id: I4AG66
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

880071:FLELI RS17010
gene id: 880071:FLELI_RS17010
uniprot id: I4AP99
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

880071:FLELI RS19535
gene id: 880071:FLELI_RS19535
uniprot id: I4AQP6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

880071:FLELI RS14230
gene id: 880071:FLELI_RS14230
uniprot id: I4AMR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

880071:FLELI RS15735
gene id: 880071:FLELI_RS15735
uniprot id: I4ANJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

880071:FLELI RS18895
gene id: 880071:FLELI_RS18895
uniprot id: I4AQB6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

880071:FLELI RS08120
gene id: 880071:FLELI_RS08120
uniprot id: I4AJE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

880071:FLELI RS00200
gene id: 880071:FLELI_RS00200
uniprot id: I4AF17
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

880071:FLELI RS00680
gene id: 880071:FLELI_RS00680
uniprot id: I4AFA3
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

880071:FLELI RS12305
gene id: 880071:FLELI_RS12305
uniprot id: I4ALP0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

880071:FLELI RS12680
gene id: 880071:FLELI_RS12680
uniprot id: I4ALW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

880071:FLELI RS18880
gene id: 880071:FLELI_RS18880
uniprot id: I4AQB3
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

880071:FLELI RS13715
gene id: 880071:FLELI_RS13715
uniprot id: I4AMG8
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

880071:FLELI RS02455
gene id: 880071:FLELI_RS02455
uniprot id: I4AG98
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

880071:FLELI RS14970
gene id: 880071:FLELI_RS14970
uniprot id: I4AN56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

880071:FLELI RS11350
gene id: 880071:FLELI_RS11350
uniprot id: I4AL54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

880071:FLELI RS05505
gene id: 880071:FLELI_RS05505
uniprot id: I4AHY4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

880071:FLELI RS03770
gene id: 880071:FLELI_RS03770
uniprot id: I4AH02
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

880071:FLELI RS03215
gene id: 880071:FLELI_RS03215
uniprot id: I4AGP2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS07740
gene id: 880071:FLELI_RS07740
uniprot id: I4AJ68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

880071:FLELI RS20120
gene id: 880071:FLELI_RS20120
uniprot id: I4AEX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

880071:FLELI RS14910
gene id: 880071:FLELI_RS14910
uniprot id: I4AN44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

880071:FLELI RS04780
gene id: 880071:FLELI_RS04780
uniprot id: I4AHJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

880071:FLELI RS12880
gene id: 880071:FLELI_RS12880
uniprot id: I4AM07
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

880071:FLELI RS10635
gene id: 880071:FLELI_RS10635
uniprot id: I4AKR4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

880071:FLELI RS14060
gene id: 880071:FLELI_RS14060
uniprot id: I4AMN5
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

880071:FLELI RS16165
gene id: 880071:FLELI_RS16165
uniprot id: I4ANT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

880071:FLELI RS08535
gene id: 880071:FLELI_RS08535
uniprot id: I4AJL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

880071:FLELI RS20185
gene id: 880071:FLELI_RS20185
uniprot id: I4AFT9
names: Similarity
messages: Belongs to the Skp family.

880071:FLELI RS12250
gene id: 880071:FLELI_RS12250
uniprot id: I4ALM7
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS07860
gene id: 880071:FLELI_RS07860
uniprot id: I4AJ92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

880071:FLELI RS04505
gene id: 880071:FLELI_RS04505
uniprot id: I4AHE8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

880071:FLELI RS06745
gene id: 880071:FLELI_RS06745
uniprot id: I4AIM8
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS00055
gene id: 880071:FLELI_RS00055
uniprot id: I4AEY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

880071:FLELI RS17270
gene id: 880071:FLELI_RS17270
uniprot id: I4APF2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

880071:FLELI RS16905
gene id: 880071:FLELI_RS16905
uniprot id: I4AP77
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

880071:FLELI RS00985
gene id: 880071:FLELI_RS00985
uniprot id: I4AFG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

880071:FLELI RS03250
gene id: 880071:FLELI_RS03250
uniprot id: I4AGP9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

880071:FLELI RS12430
gene id: 880071:FLELI_RS12430
uniprot id: I4ALR6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

880071:FLELI RS14980
gene id: 880071:FLELI_RS14980
uniprot id: I4AN58
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS04980
gene id: 880071:FLELI_RS04980
uniprot id: I4AHN6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

880071:FLELI RS13340
gene id: 880071:FLELI_RS13340
uniprot id: I4AM93
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

880071:FLELI RS19990
gene id: 880071:FLELI_RS19990
uniprot id: I4AQY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

880071:FLELI RS12560
gene id: 880071:FLELI_RS12560
uniprot id: I4ALU2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

880071:FLELI RS08140
gene id: 880071:FLELI_RS08140
uniprot id: I4AJE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

880071:FLELI RS10780
gene id: 880071:FLELI_RS10780
uniprot id: I4AKU4
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

880071:FLELI RS18000
gene id: 880071:FLELI_RS18000
uniprot id: I4APU5
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS14645
gene id: 880071:FLELI_RS14645
uniprot id: I4AMZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

880071:FLELI RS00835
gene id: 880071:FLELI_RS00835
uniprot id: I4AFD3
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

880071:FLELI RS19950
gene id: 880071:FLELI_RS19950
uniprot id: I4AQX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

880071:FLELI RS15870
gene id: 880071:FLELI_RS15870
uniprot id: I4ANM7
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

880071:FLELI RS16610
gene id: 880071:FLELI_RS16610
uniprot id: I4AP20
names: Similarity
messages: Belongs to the LacAB/RpiB family.

880071:FLELI RS15005
gene id: 880071:FLELI_RS15005
uniprot id: I4AN63
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

880071:FLELI RS14890
gene id: 880071:FLELI_RS14890
uniprot id: I4AN39
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

880071:FLELI RS09235
gene id: 880071:FLELI_RS09235
uniprot id: I4AJZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

880071:FLELI RS19830
gene id: 880071:FLELI_RS19830
uniprot id: I4AQV1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

880071:FLELI RS18460
gene id: 880071:FLELI_RS18460
uniprot id: I4AQ36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

880071:FLELI RS20660
gene id: 880071:FLELI_RS20660
uniprot id: I4ALD0
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

880071:FLELI RS08050
gene id: 880071:FLELI_RS08050
uniprot id: I4AJC7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

880071:FLELI RS03590
gene id: 880071:FLELI_RS03590
uniprot id: I4AGW5
names: Subunit
messages: Homodimer.

880071:FLELI RS07520
gene id: 880071:FLELI_RS07520
uniprot id: I4AJ26
names: Similarity
messages: Belongs to the peptidase M13 family.

880071:FLELI RS08765
gene id: 880071:FLELI_RS08765
uniprot id: I4AJQ5
names: Similarity
messages: Belongs to the SufE family.

880071:FLELI RS12610
gene id: 880071:FLELI_RS12610
uniprot id: I4ALV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

880071:FLELI RS15755
gene id: 880071:FLELI_RS15755
uniprot id: I4ANK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

880071:FLELI RS18385
gene id: 880071:FLELI_RS18385
uniprot id: I4AQ21
names: Similarity
messages: Belongs to the thioredoxin family.

880071:FLELI RS04715
gene id: 880071:FLELI_RS04715
uniprot id: I4AHI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

880071:FLELI RS18295
gene id: 880071:FLELI_RS18295
uniprot id: I4AQ03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

880071:FLELI RS17775
gene id: 880071:FLELI_RS17775
uniprot id: I4APQ1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

880071:FLELI RS13065
gene id: 880071:FLELI_RS13065
uniprot id: I4AM38
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

880071:FLELI RS07605
gene id: 880071:FLELI_RS07605
uniprot id: I4AJ41
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

880071:FLELI RS13540
gene id: 880071:FLELI_RS13540
uniprot id: I4AMD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool.
messages: Golgi apparatus
messages: Homooctamer, including four polyglutamate binding sites. The subunits are arranged as a tetramer of dimers, and form a planar ring-shaped structure.
messages: In the C-terminal section; belongs to the cyclodeaminase/cyclohydrolase family.
messages: In the N-terminal section; belongs to the formiminotransferase family.
messages: centriole

880071:FLELI RS15750
gene id: 880071:FLELI_RS15750
uniprot id: I4ANK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

880071:FLELI RS11340
gene id: 880071:FLELI_RS11340
uniprot id: I4AL51
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS01790
gene id: 880071:FLELI_RS01790
uniprot id: I4AFW1
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS10740
gene id: 880071:FLELI_RS10740
uniprot id: U3GKI4
names: Similarity
messages: Belongs to the SCO1/2 family.

880071:FLELI RS04565
gene id: 880071:FLELI_RS04565
uniprot id: I4AHG2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS00240
gene id: 880071:FLELI_RS00240
uniprot id: I4AF25
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS17310
gene id: 880071:FLELI_RS17310
uniprot id: I4APF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

880071:FLELI RS19285
gene id: 880071:FLELI_RS19285
uniprot id: I4AQJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

880071:FLELI RS19915
gene id: 880071:FLELI_RS19915
uniprot id: I4AQW8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

880071:FLELI RS16695
gene id: 880071:FLELI_RS16695
uniprot id: I4AP35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

880071:FLELI RS04335
gene id: 880071:FLELI_RS04335
uniprot id: I4AHB3
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

880071:FLELI RS10880
gene id: 880071:FLELI_RS10880
uniprot id: I4AKW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

880071:FLELI RS01860
gene id: 880071:FLELI_RS01860
uniprot id: I4AFX5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

880071:FLELI RS16800
gene id: 880071:FLELI_RS16800
uniprot id: I4AP56
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

880071:FLELI RS15725
gene id: 880071:FLELI_RS15725
uniprot id: I4ANJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

880071:FLELI RS15300
gene id: 880071:FLELI_RS15300
uniprot id: I4ANC1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

880071:FLELI RS06475
gene id: 880071:FLELI_RS06475
uniprot id: I4AIH4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

880071:FLELI RS05990
gene id: 880071:FLELI_RS05990
uniprot id: I4AI80
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Belongs to the spermidine/spermine synthase family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Homodimer or homotetramer.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS03180
gene id: 880071:FLELI_RS03180
uniprot id: I4AGN5
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS07850
gene id: 880071:FLELI_RS07850
uniprot id: I4AJ90
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS09685
gene id: 880071:FLELI_RS09685
uniprot id: I4AK76
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

880071:FLELI RS15380
gene id: 880071:FLELI_RS15380
uniprot id: I4AND6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

880071:FLELI RS11915
gene id: 880071:FLELI_RS11915
uniprot id: I4ALG2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

880071:FLELI RS08205
gene id: 880071:FLELI_RS08205
uniprot id: I4AJF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

880071:FLELI RS12800
gene id: 880071:FLELI_RS12800
uniprot id: I4ALZ1
names: Similarity
messages: Belongs to the DinB family.

880071:FLELI RS10465
gene id: 880071:FLELI_RS10465
uniprot id: I4AKN1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

880071:FLELI RS05680
gene id: 880071:FLELI_RS05680
uniprot id: I4AI18
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS16215
gene id: 880071:FLELI_RS16215
uniprot id: I4ANU7
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS08950
gene id: 880071:FLELI_RS08950
uniprot id: I4AJU2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

880071:FLELI RS10250
gene id: 880071:FLELI_RS10250
uniprot id: I4AKI9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

880071:FLELI RS12595
gene id: 880071:FLELI_RS12595
uniprot id: I4ALU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

880071:FLELI RS07350
gene id: 880071:FLELI_RS07350
uniprot id: I4AIZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

880071:FLELI RS06075
gene id: 880071:FLELI_RS06075
uniprot id: I4AI97
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS13675
gene id: 880071:FLELI_RS13675
uniprot id: I4AMG0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

880071:FLELI RS19570
gene id: 880071:FLELI_RS19570
uniprot id: I4AQQ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

880071:FLELI RS00225
gene id: 880071:FLELI_RS00225
uniprot id: I4AF22
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS12850
gene id: 880071:FLELI_RS12850
uniprot id: I4AM00
names: Similarity
messages: Belongs to the PspA/IM30 family.

880071:FLELI RS17225
gene id: 880071:FLELI_RS17225
uniprot id: I4APE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

880071:FLELI RS04300
gene id: 880071:FLELI_RS04300
uniprot id: I4AHA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

880071:FLELI RS03390
gene id: 880071:FLELI_RS03390
uniprot id: I4AGS6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

880071:FLELI RS03950
gene id: 880071:FLELI_RS03950
uniprot id: I4AH39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS09025
gene id: 880071:FLELI_RS09025
uniprot id: I4AJV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

880071:FLELI RS14005
gene id: 880071:FLELI_RS14005
uniprot id: I4AMM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

880071:FLELI RS14135
gene id: 880071:FLELI_RS14135
uniprot id: I4AMP8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

880071:FLELI RS05475
gene id: 880071:FLELI_RS05475
uniprot id: I4AHX8
names: Similarity
messages: Belongs to the peptidase S8 family.

880071:FLELI RS02800
gene id: 880071:FLELI_RS02800
uniprot id: I4AGG1
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

880071:FLELI RS19980
gene id: 880071:FLELI_RS19980
uniprot id: I4AQY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.
messages: Homotrimer.

880071:FLELI RS15340
gene id: 880071:FLELI_RS15340
uniprot id: I4ANC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

880071:FLELI RS17085
gene id: 880071:FLELI_RS17085
uniprot id: I4APB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

880071:FLELI RS19295
gene id: 880071:FLELI_RS19295
uniprot id: I4AQJ8
names: Similarity
messages: Belongs to the NodU/CmcH family.

880071:FLELI RS19125
gene id: 880071:FLELI_RS19125
uniprot id: I4AQG2
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

880071:FLELI RS18350
gene id: 880071:FLELI_RS18350
uniprot id: I4AQ14
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

880071:FLELI RS09545
gene id: 880071:FLELI_RS09545
uniprot id: I4AK52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

880071:FLELI RS14495
gene id: 880071:FLELI_RS14495
uniprot id: I4AMW6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

880071:FLELI RS17960
gene id: 880071:FLELI_RS17960
uniprot id: I4APT7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

880071:FLELI RS03185
gene id: 880071:FLELI_RS03185
uniprot id: I4AGN6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

880071:FLELI RS09405
gene id: 880071:FLELI_RS09405
uniprot id: I4AK24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

880071:FLELI RS16110
gene id: 880071:FLELI_RS16110
uniprot id: I4ANS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

880071:FLELI RS07295
gene id: 880071:FLELI_RS07295
uniprot id: I4AIY2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

880071:FLELI RS12930
gene id: 880071:FLELI_RS12930
uniprot id: I4AM14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

880071:FLELI RS16180
gene id: 880071:FLELI_RS16180
uniprot id: I4ANU0
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

880071:FLELI RS01910
gene id: 880071:FLELI_RS01910
uniprot id: I4AFY3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

880071:FLELI RS07545
gene id: 880071:FLELI_RS07545
uniprot id: I4AJ31
names: Similarity
messages: Belongs to the Skp family.

880071:FLELI RS21200
gene id: 880071:FLELI_RS21200
uniprot id: I4AK50
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

880071:FLELI RS15745
gene id: 880071:FLELI_RS15745
uniprot id: I4ANK1
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

880071:FLELI RS07040
gene id: 880071:FLELI_RS07040
uniprot id: I4AIT5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

880071:FLELI RS03355
gene id: 880071:FLELI_RS03355
uniprot id: I4AGR9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

880071:FLELI RS06115
gene id: 880071:FLELI_RS06115
uniprot id: I4AIA5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

880071:FLELI RS11795
gene id: 880071:FLELI_RS11795
uniprot id: I4ALD7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

880071:FLELI RS01240
gene id: 880071:FLELI_RS01240
uniprot id: I4AFK5
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

880071:FLELI RS16095
gene id: 880071:FLELI_RS16095
uniprot id: I4ANS2
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

880071:FLELI RS05660
gene id: 880071:FLELI_RS05660
uniprot id: I4AI14
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

880071:FLELI RS16920
gene id: 880071:FLELI_RS16920
uniprot id: I4AP80
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

880071:FLELI RS10185
gene id: 880071:FLELI_RS10185
uniprot id: I4AKH6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

880071:FLELI RS07745
gene id: 880071:FLELI_RS07745
uniprot id: I4AJ69
names: Similarity
messages: Belongs to the MscS (TC 1.A.23) family.

880071:FLELI RS17050
gene id: 880071:FLELI_RS17050
uniprot id: I4APA7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

880071:FLELI RS07085
gene id: 880071:FLELI_RS07085
uniprot id: I4AIU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

880071:FLELI RS10765
gene id: 880071:FLELI_RS10765
uniprot id: I4AKU1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

880071:FLELI RS00350
gene id: 880071:FLELI_RS00350
uniprot id: I4AF46
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

880071:FLELI RS08980
gene id: 880071:FLELI_RS08980
uniprot id: I4AJU8
names: Similarity
messages: Belongs to the heat shock protein 90 family.

880071:FLELI RS14335
gene id: 880071:FLELI_RS14335
uniprot id: I4AMT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

880071:FLELI RS06525
gene id: 880071:FLELI_RS06525
uniprot id: I4AII4
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS09390
gene id: 880071:FLELI_RS09390
uniprot id: I4AK21
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS14880
gene id: 880071:FLELI_RS14880
uniprot id: I4AN37
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

880071:FLELI RS05420
gene id: 880071:FLELI_RS05420
uniprot id: I4AHW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

880071:FLELI RS13850
gene id: 880071:FLELI_RS13850
uniprot id: I4AMJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

880071:FLELI RS14900
gene id: 880071:FLELI_RS14900
uniprot id: I4AN41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

880071:FLELI RS12830
gene id: 880071:FLELI_RS12830
uniprot id: I4ALZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

880071:FLELI RS17525
gene id: 880071:FLELI_RS17525
uniprot id: I4APK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

880071:FLELI RS07285
gene id: 880071:FLELI_RS07285
uniprot id: I4AIY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

880071:FLELI RS14340
gene id: 880071:FLELI_RS14340
uniprot id: I4AMT6
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

880071:FLELI RS05135
gene id: 880071:FLELI_RS05135
uniprot id: I4AHR6
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS14965
gene id: 880071:FLELI_RS14965
uniprot id: I4AN55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

880071:FLELI RS16315
gene id: 880071:FLELI_RS16315
uniprot id: I4ANW6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

880071:FLELI RS14640
gene id: 880071:FLELI_RS14640
uniprot id: I4AMZ2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

880071:FLELI RS14270
gene id: 880071:FLELI_RS14270
uniprot id: I4AMS3
names: Similarity
messages: Belongs to the peptidase C40 family.

880071:FLELI RS18725
gene id: 880071:FLELI_RS18725
uniprot id: I4AQ82
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

880071:FLELI RS04160
gene id: 880071:FLELI_RS04160
uniprot id: I4AH80
names: Similarity
messages: Belongs to the peptidase S41A family.

880071:FLELI RS20015
gene id: 880071:FLELI_RS20015
uniprot id: I4AQY8
names: Similarity
messages: Belongs to the peptidase C56 family.

880071:FLELI RS14960
gene id: 880071:FLELI_RS14960
uniprot id: I4AN54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

880071:FLELI RS19460
gene id: 880071:FLELI_RS19460
uniprot id: I4AQN1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

880071:FLELI RS12935
gene id: 880071:FLELI_RS12935
uniprot id: I4AM15
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

880071:FLELI RS19095
gene id: 880071:FLELI_RS19095
uniprot id: I4AQF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

880071:FLELI RS18850
gene id: 880071:FLELI_RS18850
uniprot id: I4AQA9
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS18415
gene id: 880071:FLELI_RS18415
uniprot id: I4AQ27
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

880071:FLELI RS07760
gene id: 880071:FLELI_RS07760
uniprot id: I4AJ72
names: Similarity
messages: Belongs to the BshC family.

880071:FLELI RS08680
gene id: 880071:FLELI_RS08680
uniprot id: I4AJN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

880071:FLELI RS02635
gene id: 880071:FLELI_RS02635
uniprot id: I4AGC7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS14945
gene id: 880071:FLELI_RS14945
uniprot id: I4AN51
names: Similarity
messages: Belongs to the histone deacetylase family.

880071:FLELI RS13400
gene id: 880071:FLELI_RS13400
uniprot id: I4AMA5
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

880071:FLELI RS03705
gene id: 880071:FLELI_RS03705
uniprot id: I4AGY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

880071:FLELI RS12630
gene id: 880071:FLELI_RS12630
uniprot id: I4ALV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

880071:FLELI RS02010
gene id: 880071:FLELI_RS02010
uniprot id: I4AG06
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

880071:FLELI RS09895
gene id: 880071:FLELI_RS09895
uniprot id: I4AKB8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 3-HAO family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.

880071:FLELI RS05410
gene id: 880071:FLELI_RS05410
uniprot id: I4AHW5
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

880071:FLELI RS17155
gene id: 880071:FLELI_RS17155
uniprot id: I4APC9
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

880071:FLELI RS00620
gene id: 880071:FLELI_RS00620
uniprot id: I4AF91
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

880071:FLELI RS06300
gene id: 880071:FLELI_RS06300
uniprot id: I4AIE1
names: Similarity
messages: Belongs to the RecJ family.

880071:FLELI RS10450
gene id: 880071:FLELI_RS10450
uniprot id: I4AKM9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

880071:FLELI RS08500
gene id: 880071:FLELI_RS08500
uniprot id: I4AJK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

880071:FLELI RS15800
gene id: 880071:FLELI_RS15800
uniprot id: I4ANL2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS12450
gene id: 880071:FLELI_RS12450
uniprot id: I4ALS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

880071:FLELI RS19575
gene id: 880071:FLELI_RS19575
uniprot id: I4AQQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

880071:FLELI RS16750
gene id: 880071:FLELI_RS16750
uniprot id: I4AP47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRISPR system Cmr5 family.
messages: Cytoplasm

880071:FLELI RS16030
gene id: 880071:FLELI_RS16030
uniprot id: I4ANQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

880071:FLELI RS04380
gene id: 880071:FLELI_RS04380
uniprot id: I4AHC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

880071:FLELI RS18550
gene id: 880071:FLELI_RS18550
uniprot id: I4AQ54
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS17385
gene id: 880071:FLELI_RS17385
uniprot id: I4APH4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

880071:FLELI RS09325
gene id: 880071:FLELI_RS09325
uniprot id: I4AK08
names: Similarity
messages: Belongs to the CvfB family.

880071:FLELI RS18855
gene id: 880071:FLELI_RS18855
uniprot id: I4AQB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

880071:FLELI RS03710
gene id: 880071:FLELI_RS03710
uniprot id: I4AGY9
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS01105
gene id: 880071:FLELI_RS01105
uniprot id: I4AFI4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

880071:FLELI RS19080
gene id: 880071:FLELI_RS19080
uniprot id: I4AQF3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

880071:FLELI RS17075
gene id: 880071:FLELI_RS17075
uniprot id: I4APB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

880071:FLELI RS17280
gene id: 880071:FLELI_RS17280
uniprot id: I4APF4
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS13040
gene id: 880071:FLELI_RS13040
uniprot id: I4AM33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

880071:FLELI RS05395
gene id: 880071:FLELI_RS05395
uniprot id: I4AHW2
names: Cofactor
messages: Binds 1 zinc ion per subunit.

880071:FLELI RS13260
gene id: 880071:FLELI_RS13260
uniprot id: I4AM76
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS10350
gene id: 880071:FLELI_RS10350
uniprot id: I4AKK8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

880071:FLELI RS14210
gene id: 880071:FLELI_RS14210
uniprot id: I4AMR0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS07665
gene id: 880071:FLELI_RS07665
uniprot id: I4AJ53
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

880071:FLELI RS17400
gene id: 880071:FLELI_RS17400
uniprot id: I4APH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

880071:FLELI RS15740
gene id: 880071:FLELI_RS15740
uniprot id: I4ANK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

880071:FLELI RS05695
gene id: 880071:FLELI_RS05695
uniprot id: I4AI21
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

880071:FLELI RS17765
gene id: 880071:FLELI_RS17765
uniprot id: I4APP9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

880071:FLELI RS00440
gene id: 880071:FLELI_RS00440
uniprot id: I4AF61
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

880071:FLELI RS15715
gene id: 880071:FLELI_RS15715
uniprot id: I4ANJ5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS09945
gene id: 880071:FLELI_RS09945
uniprot id: I4AKC8
names: Similarity
messages: Belongs to the glutamate synthase family.

880071:FLELI RS14375
gene id: 880071:FLELI_RS14375
uniprot id: I4AMU2
names: Similarity
messages: Belongs to the class-D beta-lactamase family.

880071:FLELI RS14845
gene id: 880071:FLELI_RS14845
uniprot id: I4AN30
names: Similarity
messages: Belongs to the aspartokinase family.

880071:FLELI RS11135
gene id: 880071:FLELI_RS11135
uniprot id: I4AL11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

880071:FLELI RS10305
gene id: 880071:FLELI_RS10305
uniprot id: I4AKK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

880071:FLELI RS08525
gene id: 880071:FLELI_RS08525
uniprot id: I4AJK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

880071:FLELI RS03065
gene id: 880071:FLELI_RS03065
uniprot id: I4AGL1
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS00420
gene id: 880071:FLELI_RS00420
uniprot id: I4AF57
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

880071:FLELI RS08770
gene id: 880071:FLELI_RS08770
uniprot id: I4AJQ6
names: Cofactor
messages: Can also use Mn(2+) ion.

880071:FLELI RS18015
gene id: 880071:FLELI_RS18015
uniprot id: I4APU7
names: Similarity
messages: Belongs to the peptidase S41A family.

880071:FLELI RS08845
gene id: 880071:FLELI_RS08845
uniprot id: I4AJS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

880071:FLELI RS18960
gene id: 880071:FLELI_RS18960
uniprot id: I4AQC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

880071:FLELI RS00870
gene id: 880071:FLELI_RS00870
uniprot id: I4AFE0
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

880071:FLELI RS20150
gene id: 880071:FLELI_RS20150
uniprot id: I4AF82
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

880071:FLELI RS13165
gene id: 880071:FLELI_RS13165
uniprot id: I4AM57
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

880071:FLELI RS07260
gene id: 880071:FLELI_RS07260
uniprot id: I4AIX6
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS16930
gene id: 880071:FLELI_RS16930
uniprot id: I4AP82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

880071:FLELI RS11025
gene id: 880071:FLELI_RS11025
uniprot id: I4AKZ0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

880071:FLELI RS19005
gene id: 880071:FLELI_RS19005
uniprot id: I4AQD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

880071:FLELI RS10735
gene id: 880071:FLELI_RS10735
uniprot id: I4AKT5
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS13355
gene id: 880071:FLELI_RS13355
uniprot id: I4AM96
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

880071:FLELI RS12740
gene id: 880071:FLELI_RS12740
uniprot id: I4ALX9
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS18570
gene id: 880071:FLELI_RS18570
uniprot id: I4AQ58
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS17805
gene id: 880071:FLELI_RS17805
uniprot id: I4APQ7
names: Similarity
messages: Belongs to the sigma-54 factor family.

880071:FLELI RS18565
gene id: 880071:FLELI_RS18565
uniprot id: I4AQ57
names: Similarity
messages: Belongs to the universal stress protein A family.

880071:FLELI RS19270
gene id: 880071:FLELI_RS19270
uniprot id: I4AQJ2
names: Similarity
messages: Belongs to the peptidase S8 family.

880071:FLELI RS09100
gene id: 880071:FLELI_RS09100
uniprot id: I4AJX2
names: Similarity
messages: Belongs to the glutamate synthase family.

880071:FLELI RS06945
gene id: 880071:FLELI_RS06945
uniprot id: I4AIR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

880071:FLELI RS10845
gene id: 880071:FLELI_RS10845
uniprot id: I4AKV7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

880071:FLELI RS09145
gene id: 880071:FLELI_RS09145
uniprot id: I4AJY1
names: Similarity
messages: Belongs to the nitroreductase family.

880071:FLELI RS15185
gene id: 880071:FLELI_RS15185
uniprot id: I4AN99
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS06540
gene id: 880071:FLELI_RS06540
uniprot id: I4AII7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS18245
gene id: 880071:FLELI_RS18245
uniprot id: I4APZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

880071:FLELI RS11000
gene id: 880071:FLELI_RS11000
uniprot id: I4AKY5
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

880071:FLELI RS08310
gene id: 880071:FLELI_RS08310
uniprot id: I4AJH6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

880071:FLELI RS08110
gene id: 880071:FLELI_RS08110
uniprot id: I4AJD8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

880071:FLELI RS01090
gene id: 880071:FLELI_RS01090
uniprot id: I4AFI1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

880071:FLELI RS09130
gene id: 880071:FLELI_RS09130
uniprot id: I4AJX8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

880071:FLELI RS15905
gene id: 880071:FLELI_RS15905
uniprot id: I4ANN3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

880071:FLELI RS19255
gene id: 880071:FLELI_RS19255
uniprot id: I4AQI9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

880071:FLELI RS00860
gene id: 880071:FLELI_RS00860
uniprot id: I4AFD8
names: Similarity
messages: Belongs to the HsdR family.

880071:FLELI RS02270
gene id: 880071:FLELI_RS02270
uniprot id: I4AG60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

880071:FLELI RS00855
gene id: 880071:FLELI_RS00855
uniprot id: I4AFD7
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

880071:FLELI RS11950
gene id: 880071:FLELI_RS11950
uniprot id: I4ALG9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

880071:FLELI RS03580
gene id: 880071:FLELI_RS03580
uniprot id: I4AGW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

880071:FLELI RS20285
gene id: 880071:FLELI_RS20285
uniprot id: I4AGW8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

880071:FLELI RS10500
gene id: 880071:FLELI_RS10500
uniprot id: I4AKN8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

880071:FLELI RS16195
gene id: 880071:FLELI_RS16195
uniprot id: I4ANU3
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

880071:FLELI RS17865
gene id: 880071:FLELI_RS17865
uniprot id: I4APR8
names: Similarity
messages: Belongs to the pyruvate kinase family.

880071:FLELI RS17545
gene id: 880071:FLELI_RS17545
uniprot id: I4APK7
names: Similarity
messages: Belongs to the NodU/CmcH family.

880071:FLELI RS11220
gene id: 880071:FLELI_RS11220
uniprot id: I4AL28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

880071:FLELI RS19085
gene id: 880071:FLELI_RS19085
uniprot id: I4AQF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

880071:FLELI RS02475
gene id: 880071:FLELI_RS02475
uniprot id: I4AGA2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

880071:FLELI RS05255
gene id: 880071:FLELI_RS05255
uniprot id: I4AHT3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

880071:FLELI RS06785
gene id: 880071:FLELI_RS06785
uniprot id: I4AIN6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS14810
gene id: 880071:FLELI_RS14810
uniprot id: I4AN23
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

880071:FLELI RS08790
gene id: 880071:FLELI_RS08790
uniprot id: I4AJR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

880071:FLELI RS08460
gene id: 880071:FLELI_RS08460
uniprot id: I4AJJ5
names: Similarity
messages: Belongs to the CapA family.

880071:FLELI RS04575
gene id: 880071:FLELI_RS04575
uniprot id: I4AHG4
names: Similarity
messages: Belongs to the DEAD box helicase family.

880071:FLELI RS07770
gene id: 880071:FLELI_RS07770
uniprot id: I4AJ74
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

880071:FLELI RS00135
gene id: 880071:FLELI_RS00135
uniprot id: I4AF04
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

880071:FLELI RS07805
gene id: 880071:FLELI_RS07805
uniprot id: I4AJ81
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

880071:FLELI RS04895
gene id: 880071:FLELI_RS04895
uniprot id: I4AHM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

880071:FLELI RS14915
gene id: 880071:FLELI_RS14915
uniprot id: I4AN45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

880071:FLELI RS16990
gene id: 880071:FLELI_RS16990
uniprot id: I4AP95
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

880071:FLELI RS06135
gene id: 880071:FLELI_RS06135
uniprot id: I4AIA8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS08150
gene id: 880071:FLELI_RS08150
uniprot id: I4AJE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

880071:FLELI RS10375
gene id: 880071:FLELI_RS10375
uniprot id: I4AKL3
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

880071:FLELI RS19700
gene id: 880071:FLELI_RS19700
uniprot id: I4AQS7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

880071:FLELI RS08710
gene id: 880071:FLELI_RS08710
uniprot id: I4AJP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

880071:FLELI RS06770
gene id: 880071:FLELI_RS06770
uniprot id: I4AIN3
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

880071:FLELI RS02790
gene id: 880071:FLELI_RS02790
uniprot id: I4AGF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

880071:FLELI RS07010
gene id: 880071:FLELI_RS07010
uniprot id: I4AIS9
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

880071:FLELI RS13150
gene id: 880071:FLELI_RS13150
uniprot id: I4AM55
names: Similarity
messages: Belongs to the GARS family.

880071:FLELI RS06940
gene id: 880071:FLELI_RS06940
uniprot id: I4AIR5
names: Caution
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS14250
gene id: 880071:FLELI_RS14250
uniprot id: I4AMR9
names: Similarity
messages: Belongs to the UPF0045 family.

880071:FLELI RS18695
gene id: 880071:FLELI_RS18695
uniprot id: I4AQ78
names: Similarity
messages: Belongs to the peptidase C40 family.

880071:FLELI RS11140
gene id: 880071:FLELI_RS11140
uniprot id: I4AL12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

880071:FLELI RS15085
gene id: 880071:FLELI_RS15085
uniprot id: I4AN79
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS04630
gene id: 880071:FLELI_RS04630
uniprot id: I4AHH3
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS18390
gene id: 880071:FLELI_RS18390
uniprot id: I4AQ22
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

880071:FLELI RS09845
gene id: 880071:FLELI_RS09845
uniprot id: I4AKA8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

880071:FLELI RS10825
gene id: 880071:FLELI_RS10825
uniprot id: I4AKV3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

880071:FLELI RS05065
gene id: 880071:FLELI_RS05065
uniprot id: I4AHQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

880071:FLELI RS06985
gene id: 880071:FLELI_RS06985
uniprot id: I4AIS4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

880071:FLELI RS17895
gene id: 880071:FLELI_RS17895
uniprot id: I4APS4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

880071:FLELI RS09655
gene id: 880071:FLELI_RS09655
uniprot id: I4AK70
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

880071:FLELI RS15910
gene id: 880071:FLELI_RS15910
uniprot id: I4ANN4
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

880071:FLELI RS14020
gene id: 880071:FLELI_RS14020
uniprot id: I4AMM8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

880071:FLELI RS02110
gene id: 880071:FLELI_RS02110
uniprot id: I4AG26
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS03105
gene id: 880071:FLELI_RS03105
uniprot id: I4AGL9
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

880071:FLELI RS02745
gene id: 880071:FLELI_RS02745
uniprot id: I4AGE9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

880071:FLELI RS03585
gene id: 880071:FLELI_RS03585
uniprot id: I4AGW4
names: Similarity
messages: Belongs to the threonine synthase family.

880071:FLELI RS12580
gene id: 880071:FLELI_RS12580
uniprot id: I4ALU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

880071:FLELI RS03310
gene id: 880071:FLELI_RS03310
uniprot id: I4AGR2
names: Similarity
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

880071:FLELI RS10395
gene id: 880071:FLELI_RS10395
uniprot id: I4AKL8
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

880071:FLELI RS13945
gene id: 880071:FLELI_RS13945
uniprot id: I4AML4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

880071:FLELI RS04200
gene id: 880071:FLELI_RS04200
uniprot id: I4AH88
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

880071:FLELI RS14130
gene id: 880071:FLELI_RS14130
uniprot id: I4AMP7
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

880071:FLELI RS02840
gene id: 880071:FLELI_RS02840
uniprot id: I4AGG9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

880071:FLELI RS00565
gene id: 880071:FLELI_RS00565
uniprot id: I4AF80
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

880071:FLELI RS13975
gene id: 880071:FLELI_RS13975
uniprot id: I4AML9
names: Similarity
messages: Belongs to the peptidase S8 family.

880071:FLELI RS19930
gene id: 880071:FLELI_RS19930
uniprot id: I4AQX1
names: Similarity
messages: Belongs to the DprA/Smf family.

880071:FLELI RS11145
gene id: 880071:FLELI_RS11145
uniprot id: I4AL13
names: Similarity
messages: Belongs to the glutathione peroxidase family.

880071:FLELI RS07320
gene id: 880071:FLELI_RS07320
uniprot id: I4AIY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

880071:FLELI RS19070
gene id: 880071:FLELI_RS19070
uniprot id: I4AQF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

880071:FLELI RS15595
gene id: 880071:FLELI_RS15595
uniprot id: I4ANH1
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS15455
gene id: 880071:FLELI_RS15455
uniprot id: I4ANE8
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

880071:FLELI RS10310
gene id: 880071:FLELI_RS10310
uniprot id: I4AKK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

880071:FLELI RS09500
gene id: 880071:FLELI_RS09500
uniprot id: I4AK41
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS19920
gene id: 880071:FLELI_RS19920
uniprot id: I4AQW9
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

880071:FLELI RS14540
gene id: 880071:FLELI_RS14540
uniprot id: I4AMX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

880071:FLELI RS12625
gene id: 880071:FLELI_RS12625
uniprot id: I4ALV5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

880071:FLELI RS17260
gene id: 880071:FLELI_RS17260
uniprot id: I4APF0
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS06830
gene id: 880071:FLELI_RS06830
uniprot id: I4AIP5
names: Similarity
messages: Belongs to the thioesterase PaaI family.

880071:FLELI RS13565
gene id: 880071:FLELI_RS13565
uniprot id: I4AMD8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

880071:FLELI RS14320
gene id: 880071:FLELI_RS14320
uniprot id: I4AMT2
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS08930
gene id: 880071:FLELI_RS08930
uniprot id: I4AJT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

880071:FLELI RS10805
gene id: 880071:FLELI_RS10805
uniprot id: I4AKU9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

880071:FLELI RS09640
gene id: 880071:FLELI_RS09640
uniprot id: I4AK67
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

880071:FLELI RS13060
gene id: 880071:FLELI_RS13060
uniprot id: I4AM37
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

880071:FLELI RS16935
gene id: 880071:FLELI_RS16935
uniprot id: I4AP83
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

880071:FLELI RS15315
gene id: 880071:FLELI_RS15315
uniprot id: I4ANC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

880071:FLELI RS01020
gene id: 880071:FLELI_RS01020
uniprot id: I4AFG7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

880071:FLELI RS18985
gene id: 880071:FLELI_RS18985
uniprot id: I4AQD4
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS17265
gene id: 880071:FLELI_RS17265
uniprot id: I4APF1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

880071:FLELI RS18785
gene id: 880071:FLELI_RS18785
uniprot id: I4AQ95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

880071:FLELI RS08905
gene id: 880071:FLELI_RS08905
uniprot id: I4AJT3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

880071:FLELI RS09775
gene id: 880071:FLELI_RS09775
uniprot id: I4AK94
names: Similarity
messages: Belongs to the OsmC/Ohr family.

880071:FLELI RS07550
gene id: 880071:FLELI_RS07550
uniprot id: I4AJ32
names: Similarity
messages: Belongs to the Skp family.

880071:FLELI RS20045
gene id: 880071:FLELI_RS20045
uniprot id: I4AQZ4
names: Similarity
messages: Belongs to the SufE family.

880071:FLELI RS03200
gene id: 880071:FLELI_RS03200
uniprot id: I4AGN9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

880071:FLELI RS20095
gene id: 880071:FLELI_RS20095
uniprot id: I4AR03
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

880071:FLELI RS14435
gene id: 880071:FLELI_RS14435
uniprot id: I4AMV4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

880071:FLELI RS15200
gene id: 880071:FLELI_RS15200
uniprot id: I4ANA2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

880071:FLELI RS19435
gene id: 880071:FLELI_RS19435
uniprot id: I4AQM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

880071:FLELI RS14620
gene id: 880071:FLELI_RS14620
uniprot id: I4AMY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

880071:FLELI RS03690
gene id: 880071:FLELI_RS03690
uniprot id: I4AGY5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

880071:FLELI RS13360
gene id: 880071:FLELI_RS13360
uniprot id: I4AM97
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

880071:FLELI RS18335
gene id: 880071:FLELI_RS18335
uniprot id: I4AQ11
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

880071:FLELI RS10360
gene id: 880071:FLELI_RS10360
uniprot id: I4AKL0
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

880071:FLELI RS16470
gene id: 880071:FLELI_RS16470
uniprot id: I4ANZ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS18370
gene id: 880071:FLELI_RS18370
uniprot id: I4AQ18
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS13050
gene id: 880071:FLELI_RS13050
uniprot id: I4AM35
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

880071:FLELI RS03070
gene id: 880071:FLELI_RS03070
uniprot id: I4AGL2
names: Similarity
messages: Belongs to the fabD family.

880071:FLELI RS19045
gene id: 880071:FLELI_RS19045
uniprot id: I4AQE6
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

880071:FLELI RS09355
gene id: 880071:FLELI_RS09355
uniprot id: I4AK14
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

880071:FLELI RS05760
gene id: 880071:FLELI_RS05760
uniprot id: I4AI35
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

880071:FLELI RS08355
gene id: 880071:FLELI_RS08355
uniprot id: I4AJI5
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

880071:FLELI RS13530
gene id: 880071:FLELI_RS13530
uniprot id: I4AMD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

880071:FLELI RS03175
gene id: 880071:FLELI_RS03175
uniprot id: I4AGN3
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

880071:FLELI RS19925
gene id: 880071:FLELI_RS19925
uniprot id: I4AQX0
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

880071:FLELI RS19770
gene id: 880071:FLELI_RS19770
uniprot id: I4AQU1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

880071:FLELI RS06480
gene id: 880071:FLELI_RS06480
uniprot id: I4AIH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

880071:FLELI RS05205
gene id: 880071:FLELI_RS05205
uniprot id: I4AHS2
names: Similarity
messages: Belongs to the ComB family.

880071:FLELI RS09590
gene id: 880071:FLELI_RS09590
uniprot id: I4AK57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

880071:FLELI RS19730
gene id: 880071:FLELI_RS19730
uniprot id: I4AQT3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

880071:FLELI RS02945
gene id: 880071:FLELI_RS02945
uniprot id: I4AGI7
names: Cofactor
names: PTM
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.

880071:FLELI RS19430
gene id: 880071:FLELI_RS19430
uniprot id: I4AQM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

880071:FLELI RS10220
gene id: 880071:FLELI_RS10220
uniprot id: I4AKI3
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

880071:FLELI RS01695
gene id: 880071:FLELI_RS01695
uniprot id: I4AFU1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

880071:FLELI RS12715
gene id: 880071:FLELI_RS12715
uniprot id: I4ALX4
names: Similarity
messages: Belongs to the peptidase S9A family.

880071:FLELI RS13955
gene id: 880071:FLELI_RS13955
uniprot id: I4AML6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

880071:FLELI RS04890
gene id: 880071:FLELI_RS04890
uniprot id: I4AHL9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

880071:FLELI RS00155
gene id: 880071:FLELI_RS00155
uniprot id: I4AF08
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

880071:FLELI RS06030
gene id: 880071:FLELI_RS06030
uniprot id: I4AI88
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS19230
gene id: 880071:FLELI_RS19230
uniprot id: I4AQI3
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS01705
gene id: 880071:FLELI_RS01705
uniprot id: I4AFU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

880071:FLELI RS16385
gene id: 880071:FLELI_RS16385
uniprot id: I4ANY0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

880071:FLELI RS16640
gene id: 880071:FLELI_RS16640
uniprot id: I4AP25
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS02310
gene id: 880071:FLELI_RS02310
uniprot id: I4AG68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

880071:FLELI RS03400
gene id: 880071:FLELI_RS03400
uniprot id: I4AGS8
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

880071:FLELI RS15525
gene id: 880071:FLELI_RS15525
uniprot id: I4ANG2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

880071:FLELI RS14955
gene id: 880071:FLELI_RS14955
uniprot id: I4AN53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

880071:FLELI RS00990
gene id: 880071:FLELI_RS00990
uniprot id: I4AFG1
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS12285
gene id: 880071:FLELI_RS12285
uniprot id: I4ALN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

880071:FLELI RS14170
gene id: 880071:FLELI_RS14170
uniprot id: I4AMQ5
names: Similarity
messages: Belongs to the UPF0246 family.

880071:FLELI RS03715
gene id: 880071:FLELI_RS03715
uniprot id: I4AGZ0
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

880071:FLELI RS14030
gene id: 880071:FLELI_RS14030
uniprot id: I4AMN0
names: Similarity
messages: Belongs to the SUI1 family.

880071:FLELI RS04150
gene id: 880071:FLELI_RS04150
uniprot id: I4AH78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

880071:FLELI RS09155
gene id: 880071:FLELI_RS09155
uniprot id: I4AJY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

880071:FLELI RS07305
gene id: 880071:FLELI_RS07305
uniprot id: I4AIY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

880071:FLELI RS14310
gene id: 880071:FLELI_RS14310
uniprot id: I4AMT0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

880071:FLELI RS15960
gene id: 880071:FLELI_RS15960
uniprot id: I4ANP6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

880071:FLELI RS09445
gene id: 880071:FLELI_RS09445
uniprot id: I4AK32
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

880071:FLELI RS16615
gene id: 880071:FLELI_RS16615
uniprot id: I4AP21
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

880071:FLELI RS11085
gene id: 880071:FLELI_RS11085
uniprot id: I4AL02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

880071:FLELI RS14525
gene id: 880071:FLELI_RS14525
uniprot id: I4AMX0
names: Similarity
messages: Belongs to the phosphosulfolactate synthase family.

880071:FLELI RS10210
gene id: 880071:FLELI_RS10210
uniprot id: I4AKI1
names: Similarity
messages: Belongs to the PspA/IM30 family.

880071:FLELI RS12320
gene id: 880071:FLELI_RS12320
uniprot id: I4ALP3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

880071:FLELI RS08470
gene id: 880071:FLELI_RS08470
uniprot id: I4AJJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

880071:FLELI RS02285
gene id: 880071:FLELI_RS02285
uniprot id: I4AG63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

880071:FLELI RS08550
gene id: 880071:FLELI_RS08550
uniprot id: I4AJL3
names: Similarity
messages: Belongs to the asparagine synthetase family.

880071:FLELI RS16890
gene id: 880071:FLELI_RS16890
uniprot id: I4AP74
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

880071:FLELI RS09630
gene id: 880071:FLELI_RS09630
uniprot id: I4AK65
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

880071:FLELI RS18330
gene id: 880071:FLELI_RS18330
uniprot id: I4AQ10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

880071:FLELI RS04340
gene id: 880071:FLELI_RS04340
uniprot id: I4AHB4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS13865
gene id: 880071:FLELI_RS13865
uniprot id: I4AMJ8
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

880071:FLELI RS01075
gene id: 880071:FLELI_RS01075
uniprot id: I4AFH8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

880071:FLELI RS13620
gene id: 880071:FLELI_RS13620
uniprot id: I4AME9
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

880071:FLELI RS08600
gene id: 880071:FLELI_RS08600
uniprot id: I4AJM3
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

880071:FLELI RS13585
gene id: 880071:FLELI_RS13585
uniprot id: I4AME2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

880071:FLELI RS11980
gene id: 880071:FLELI_RS11980
uniprot id: I4ALH5
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS15275
gene id: 880071:FLELI_RS15275
uniprot id: I4ANB6
names: Similarity
messages: Belongs to the nitroreductase family.

880071:FLELI RS19640
gene id: 880071:FLELI_RS19640
uniprot id: I4AQR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

880071:FLELI RS14055
gene id: 880071:FLELI_RS14055
uniprot id: I4AMN4
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

880071:FLELI RS19605
gene id: 880071:FLELI_RS19605
uniprot id: I4AQR0
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

880071:FLELI RS09645
gene id: 880071:FLELI_RS09645
uniprot id: I4AK68
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

880071:FLELI RS14615
gene id: 880071:FLELI_RS14615
uniprot id: I4AMY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

880071:FLELI RS10045
gene id: 880071:FLELI_RS10045
uniprot id: I4AKE9
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

880071:FLELI RS06925
gene id: 880071:FLELI_RS06925
uniprot id: I4AIR2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS17060
gene id: 880071:FLELI_RS17060
uniprot id: I4APA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

880071:FLELI RS11885
gene id: 880071:FLELI_RS11885
uniprot id: I4ALF6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.
messages: Belongs to the aromatic-ring hydroxylase family. TetX subfamily.
messages: Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.
messages: Cytoplasm
messages: Monomer.

880071:FLELI RS08270
gene id: 880071:FLELI_RS08270
uniprot id: I4AJG7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

880071:FLELI RS06765
gene id: 880071:FLELI_RS06765
uniprot id: I4AIN2
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS18500
gene id: 880071:FLELI_RS18500
uniprot id: I4AQ45
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

880071:FLELI RS11775
gene id: 880071:FLELI_RS11775
uniprot id: I4ALD3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS18470
gene id: 880071:FLELI_RS18470
uniprot id: I4AQ38
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

880071:FLELI RS17185
gene id: 880071:FLELI_RS17185
uniprot id: I4APD5
names: Similarity
messages: Belongs to the peptidase S66 family.

880071:FLELI RS03775
gene id: 880071:FLELI_RS03775
uniprot id: I4AH03
names: Similarity
messages: Belongs to the ribF family.

880071:FLELI RS03970
gene id: 880071:FLELI_RS03970
uniprot id: I4AH43
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

880071:FLELI RS05675
gene id: 880071:FLELI_RS05675
uniprot id: I4AI17
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

880071:FLELI RS11170
gene id: 880071:FLELI_RS11170
uniprot id: I4AL18
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

880071:FLELI RS01065
gene id: 880071:FLELI_RS01065
uniprot id: I4AFH6
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

880071:FLELI RS05500
gene id: 880071:FLELI_RS05500
uniprot id: I4AHY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

880071:FLELI RS02815
gene id: 880071:FLELI_RS02815
uniprot id: I4AGG4
names: Similarity
messages: Belongs to the asparaginase 1 family.

880071:FLELI RS17730
gene id: 880071:FLELI_RS17730
uniprot id: I4APP2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

880071:FLELI RS19265
gene id: 880071:FLELI_RS19265
uniprot id: I4AQJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

880071:FLELI RS10810
gene id: 880071:FLELI_RS10810
uniprot id: I4AKV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

880071:FLELI RS05210
gene id: 880071:FLELI_RS05210
uniprot id: I4AHS3
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

880071:FLELI RS16790
gene id: 880071:FLELI_RS16790
uniprot id: I4AP54
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

880071:FLELI RS20970
gene id: 880071:FLELI_RS20970
uniprot id: I4AQV4
names: Similarity
messages: Belongs to the peptidase C40 family.

880071:FLELI RS19750
gene id: 880071:FLELI_RS19750
uniprot id: I4AQT7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

880071:FLELI RS05435
gene id: 880071:FLELI_RS05435
uniprot id: I4AHX0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

880071:FLELI RS07155
gene id: 880071:FLELI_RS07155
uniprot id: I4AIV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

880071:FLELI RS07965
gene id: 880071:FLELI_RS07965
uniprot id: I4AJB2
names: Similarity
messages: Belongs to the threonine synthase family.

880071:FLELI RS09970
gene id: 880071:FLELI_RS09970
uniprot id: I4AKD3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

880071:FLELI RS20005
gene id: 880071:FLELI_RS20005
uniprot id: I4AQY6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS05425
gene id: 880071:FLELI_RS05425
uniprot id: I4AHW8
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

880071:FLELI RS09540
gene id: 880071:FLELI_RS09540
uniprot id: I4AK49
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

880071:FLELI RS11330
gene id: 880071:FLELI_RS11330
uniprot id: I4AL49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

880071:FLELI RS19480
gene id: 880071:FLELI_RS19480
uniprot id: I4AQN5
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS02480
gene id: 880071:FLELI_RS02480
uniprot id: I4AGA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

880071:FLELI RS09165
gene id: 880071:FLELI_RS09165
uniprot id: I4AJY5
names: Subcellular Location Annotation
messages: Cytoplasm

880071:FLELI RS10560
gene id: 880071:FLELI_RS10560
uniprot id: I4AKP9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS19945
gene id: 880071:FLELI_RS19945
uniprot id: I4AQX4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

880071:FLELI RS08940
gene id: 880071:FLELI_RS08940
uniprot id: I4AJU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

880071:FLELI RS06605
gene id: 880071:FLELI_RS06605
uniprot id: I4AIK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

880071:FLELI RS06815
gene id: 880071:FLELI_RS06815
uniprot id: I4AIP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

880071:FLELI RS02190
gene id: 880071:FLELI_RS02190
uniprot id: I4AG43
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

880071:FLELI RS18065
gene id: 880071:FLELI_RS18065
uniprot id: I4APV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

880071:FLELI RS04850
gene id: 880071:FLELI_RS04850
uniprot id: I4AHL2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

880071:FLELI RS19645
gene id: 880071:FLELI_RS19645
uniprot id: I4AQR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

880071:FLELI RS05825
gene id: 880071:FLELI_RS05825
uniprot id: I4AI48
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS13910
gene id: 880071:FLELI_RS13910
uniprot id: I4AMK7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

880071:FLELI RS06445
gene id: 880071:FLELI_RS06445
uniprot id: I4AIG8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

880071:FLELI RS03020
gene id: 880071:FLELI_RS03020
uniprot id: I4AGK2
names: Similarity
messages: Belongs to the ClpA/ClpB family.

880071:FLELI RS14530
gene id: 880071:FLELI_RS14530
uniprot id: I4AMX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

880071:FLELI RS19900
gene id: 880071:FLELI_RS19900
uniprot id: I4AQW5
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

880071:FLELI RS12605
gene id: 880071:FLELI_RS12605
uniprot id: I4ALV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

880071:FLELI RS04240
gene id: 880071:FLELI_RS04240
uniprot id: I4AH96
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS08195
gene id: 880071:FLELI_RS08195
uniprot id: I4AJF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

880071:FLELI RS11385
gene id: 880071:FLELI_RS11385
uniprot id: I4AL61
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

880071:FLELI RS19040
gene id: 880071:FLELI_RS19040
uniprot id: I4AQE5
names: Similarity
messages: Belongs to the peptidase S8 family.

880071:FLELI RS18435
gene id: 880071:FLELI_RS18435
uniprot id: I4AQ31
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS19985
gene id: 880071:FLELI_RS19985
uniprot id: I4AQY2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

880071:FLELI RS02115
gene id: 880071:FLELI_RS02115
uniprot id: I4AG27
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

880071:FLELI RS01615
gene id: 880071:FLELI_RS01615
uniprot id: I4AFS7
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

880071:FLELI RS00875
gene id: 880071:FLELI_RS00875
uniprot id: I4AFE1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

880071:FLELI RS09030
gene id: 880071:FLELI_RS09030
uniprot id: I4AJV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

880071:FLELI RS00020
gene id: 880071:FLELI_RS00020
uniprot id: I4AEY1
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS03700
gene id: 880071:FLELI_RS03700
uniprot id: I4AGY7
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

880071:FLELI RS18425
gene id: 880071:FLELI_RS18425
uniprot id: I4AQ29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

880071:FLELI RS12835
gene id: 880071:FLELI_RS12835
uniprot id: I4ALZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

880071:FLELI RS16390
gene id: 880071:FLELI_RS16390
uniprot id: I4ANY1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

880071:FLELI RS19345
gene id: 880071:FLELI_RS19345
uniprot id: I4AQK9
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

880071:FLELI RS14605
gene id: 880071:FLELI_RS14605
uniprot id: I4AMY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

880071:FLELI RS01865
gene id: 880071:FLELI_RS01865
uniprot id: I4AFX6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

880071:FLELI RS15955
gene id: 880071:FLELI_RS15955
uniprot id: I4ANP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

880071:FLELI RS20145
gene id: 880071:FLELI_RS20145
uniprot id: I4AF81
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

880071:FLELI RS18110
gene id: 880071:FLELI_RS18110
uniprot id: I4APW7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS05710
gene id: 880071:FLELI_RS05710
uniprot id: I4AI25
names: Similarity
messages: Belongs to the CapA family.

880071:FLELI RS08155
gene id: 880071:FLELI_RS08155
uniprot id: I4AJE7
names: Similarity
messages: Belongs to the UPF0162 family.

880071:FLELI RS16850
gene id: 880071:FLELI_RS16850
uniprot id: I4AP66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

880071:FLELI RS16585
gene id: 880071:FLELI_RS16585
uniprot id: I4AP15
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

880071:FLELI RS16875
gene id: 880071:FLELI_RS16875
uniprot id: I4AP71
names: Similarity
messages: Belongs to the Gfa family.

880071:FLELI RS11970
gene id: 880071:FLELI_RS11970
uniprot id: I4ALH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

880071:FLELI RS06095
gene id: 880071:FLELI_RS06095
uniprot id: I4AIA1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

880071:FLELI RS15480
gene id: 880071:FLELI_RS15480
uniprot id: I4ANF3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

880071:FLELI RS15590
gene id: 880071:FLELI_RS15590
uniprot id: I4ANH0
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

880071:FLELI RS10475
gene id: 880071:FLELI_RS10475
uniprot id: I4AKN3
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS15345
gene id: 880071:FLELI_RS15345
uniprot id: I4AND0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

880071:FLELI RS08895
gene id: 880071:FLELI_RS08895
uniprot id: I4AJT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

880071:FLELI RS06255
gene id: 880071:FLELI_RS06255
uniprot id: I4AID1
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS06715
gene id: 880071:FLELI_RS06715
uniprot id: I4AIM2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

880071:FLELI RS05050
gene id: 880071:FLELI_RS05050
uniprot id: I4AHP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

880071:FLELI RS06370
gene id: 880071:FLELI_RS06370
uniprot id: I4AIF3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

880071:FLELI RS07125
gene id: 880071:FLELI_RS07125
uniprot id: I4AIV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

880071:FLELI RS02155
gene id: 880071:FLELI_RS02155
uniprot id: I4AG36
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS09585
gene id: 880071:FLELI_RS09585
uniprot id: I4AK56
names: Similarity
messages: Belongs to the universal stress protein A family.

880071:FLELI RS01565
gene id: 880071:FLELI_RS01565
uniprot id: I4AFS0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

880071:FLELI RS16455
gene id: 880071:FLELI_RS16455
uniprot id: I4ANZ4
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

880071:FLELI RS14710
gene id: 880071:FLELI_RS14710
uniprot id: I4AN05
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

880071:FLELI RS04470
gene id: 880071:FLELI_RS04470
uniprot id: I4AHE1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

880071:FLELI RS05975
gene id: 880071:FLELI_RS05975
uniprot id: I4AI77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

880071:FLELI RS20020
gene id: 880071:FLELI_RS20020
uniprot id: I4AQY9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

880071:FLELI RS04755
gene id: 880071:FLELI_RS04755
uniprot id: I4AHJ5
names: Similarity
messages: Belongs to the citrate synthase family.

880071:FLELI RS17395
gene id: 880071:FLELI_RS17395
uniprot id: I4APH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

880071:FLELI RS04105
gene id: 880071:FLELI_RS04105
uniprot id: I4AH70
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

880071:FLELI RS12710
gene id: 880071:FLELI_RS12710
uniprot id: I4ALX3
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS16205
gene id: 880071:FLELI_RS16205
uniprot id: I4ANU5
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

880071:FLELI RS08130
gene id: 880071:FLELI_RS08130
uniprot id: I4AJE2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

880071:FLELI RS17920
gene id: 880071:FLELI_RS17920
uniprot id: I4APS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

880071:FLELI RS09580
gene id: 880071:FLELI_RS09580
uniprot id: I4AK55
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

880071:FLELI RS04225
gene id: 880071:FLELI_RS04225
uniprot id: I4AH93
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

880071:FLELI RS17000
gene id: 880071:FLELI_RS17000
uniprot id: I4AP97
names: Similarity
messages: Belongs to the DtxR/MntR family.

880071:FLELI RS02450
gene id: 880071:FLELI_RS02450
uniprot id: I4AG97
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS15935
gene id: 880071:FLELI_RS15935
uniprot id: I4ANP0
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

880071:FLELI RS11215
gene id: 880071:FLELI_RS11215
uniprot id: I4AL27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

880071:FLELI RS07410
gene id: 880071:FLELI_RS07410
uniprot id: I4AJ04
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

880071:FLELI RS14565
gene id: 880071:FLELI_RS14565
uniprot id: I4AMX8
names: Subcellular Location Annotation
messages: Membrane

880071:FLELI RS01795
gene id: 880071:FLELI_RS01795
uniprot id: I4AFW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

880071:FLELI RS17065
gene id: 880071:FLELI_RS17065
uniprot id: I4APB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

880071:FLELI RS16865
gene id: 880071:FLELI_RS16865
uniprot id: I4AP69
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

880071:FLELI RS09650
gene id: 880071:FLELI_RS09650
uniprot id: I4AK69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

880071:FLELI RS16190
gene id: 880071:FLELI_RS16190
uniprot id: I4ANU2
names: Similarity
messages: Belongs to the CutA family.

880071:FLELI RS07195
gene id: 880071:FLELI_RS07195
uniprot id: I4AIW4
names: Similarity
messages: Belongs to the thioesterase PaaI family.