879243:PORAS RS01650
gene id: 879243:PORAS_RS01650
uniprot id: F4KMN9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

879243:PORAS RS00865
gene id: 879243:PORAS_RS00865
uniprot id: F4KLM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

879243:PORAS RS04435
gene id: 879243:PORAS_RS04435
uniprot id: F4KKA7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

879243:PORAS RS03375
gene id: 879243:PORAS_RS03375
uniprot id: F4KJQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

879243:PORAS RS04140
gene id: 879243:PORAS_RS04140
uniprot id: F4KK50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

879243:PORAS RS04820
gene id: 879243:PORAS_RS04820
uniprot id: F4KKI3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

879243:PORAS RS05520
gene id: 879243:PORAS_RS05520
uniprot id: F4KL32
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

879243:PORAS RS01595
gene id: 879243:PORAS_RS01595
uniprot id: F4KMG0
names: Similarity
messages: Belongs to the peptidase S41A family.

879243:PORAS RS02425
gene id: 879243:PORAS_RS02425
uniprot id: F4KNI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

879243:PORAS RS03685
gene id: 879243:PORAS_RS03685
uniprot id: F4KJW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

879243:PORAS RS04670
gene id: 879243:PORAS_RS04670
uniprot id: F4KKF3
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS06900
gene id: 879243:PORAS_RS06900
uniprot id: F4KMM0
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS08445
gene id: 879243:PORAS_RS08445
uniprot id: F4KJK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

879243:PORAS RS03680
gene id: 879243:PORAS_RS03680
uniprot id: F4KJW2
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

879243:PORAS RS00480
gene id: 879243:PORAS_RS00480
uniprot id: F4KL77
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

879243:PORAS RS02110
gene id: 879243:PORAS_RS02110
uniprot id: F4KN47
names: Similarity
messages: Belongs to the peptidase C25 family.

879243:PORAS RS00115
gene id: 879243:PORAS_RS00115
uniprot id: F4KKU6
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

879243:PORAS RS05895
gene id: 879243:PORAS_RS05895
uniprot id: F4KLH3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS01680
gene id: 879243:PORAS_RS01680
uniprot id: F4KMP5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

879243:PORAS RS07490
gene id: 879243:PORAS_RS07490
uniprot id: F4KNC4
names: Similarity
messages: Belongs to the sigma-54 factor family.

879243:PORAS RS05195
gene id: 879243:PORAS_RS05195
uniprot id: F4KKR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

879243:PORAS RS05830
gene id: 879243:PORAS_RS05830
uniprot id: F4KLG0
names: Similarity
messages: Belongs to the Skp family.

879243:PORAS RS01600
gene id: 879243:PORAS_RS01600
uniprot id: F4KMG1
names: Similarity
messages: Belongs to the type IA topoisomerase family.

879243:PORAS RS08355
gene id: 879243:PORAS_RS08355
uniprot id: F4KJI7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS05060
gene id: 879243:PORAS_RS05060
uniprot id: F4KJD1
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

879243:PORAS RS07560
gene id: 879243:PORAS_RS07560
uniprot id: F4KND8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS06435
gene id: 879243:PORAS_RS06435
uniprot id: F4KM60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

879243:PORAS RS08160
gene id: 879243:PORAS_RS08160
uniprot id: F4KP41
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

879243:PORAS RS07950
gene id: 879243:PORAS_RS07950
uniprot id: F4KNZ9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

879243:PORAS RS05610
gene id: 879243:PORAS_RS05610
uniprot id: F4KLB4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

879243:PORAS RS06525
gene id: 879243:PORAS_RS06525
uniprot id: F4KM78
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

879243:PORAS RS05640
gene id: 879243:PORAS_RS05640
uniprot id: F4KLC1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

879243:PORAS RS03250
gene id: 879243:PORAS_RS03250
uniprot id: F4KJN2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

879243:PORAS RS05470
gene id: 879243:PORAS_RS05470
uniprot id: F4KL21
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

879243:PORAS RS00440
gene id: 879243:PORAS_RS00440
uniprot id: F4KL69
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

879243:PORAS RS02485
gene id: 879243:PORAS_RS02485
uniprot id: F4KNJ2
names: Similarity
messages: Belongs to the peptidase M24B family.

879243:PORAS RS06520
gene id: 879243:PORAS_RS06520
uniprot id: F4KM77
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS05435
gene id: 879243:PORAS_RS05435
uniprot id: F4KL17
names: Similarity
messages: Belongs to the heat shock protein 90 family.

879243:PORAS RS02380
gene id: 879243:PORAS_RS02380
uniprot id: F4KNH2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

879243:PORAS RS00185
gene id: 879243:PORAS_RS00185
uniprot id: F4KKW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

879243:PORAS RS00050
gene id: 879243:PORAS_RS00050
uniprot id: F4KKT2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

879243:PORAS RS01520
gene id: 879243:PORAS_RS01520
uniprot id: F4KME5
names: Similarity
messages: Belongs to the RecJ family.

879243:PORAS RS08470
gene id: 879243:PORAS_RS08470
uniprot id: F4KJL0
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

879243:PORAS RS01000
gene id: 879243:PORAS_RS01000
uniprot id: F4KLW7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

879243:PORAS RS02065
gene id: 879243:PORAS_RS02065
uniprot id: F4KN38
names: Subcellular Location Annotation
messages: Cytoplasm

879243:PORAS RS08420
gene id: 879243:PORAS_RS08420
uniprot id: F4KJK0
names: Similarity
messages: Belongs to the fabD family.

879243:PORAS RS00830
gene id: 879243:PORAS_RS00830
uniprot id: F4KLL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

879243:PORAS RS03455
gene id: 879243:PORAS_RS03455
uniprot id: F4KJS0
names: Similarity
messages: Belongs to the MreC family.

879243:PORAS RS08465
gene id: 879243:PORAS_RS08465
uniprot id: F4KJK9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

879243:PORAS RS00945
gene id: 879243:PORAS_RS00945
uniprot id: F4KLN7
names: Similarity
messages: Belongs to the peptidase S13 family.

879243:PORAS RS03745
gene id: 879243:PORAS_RS03745
uniprot id: F4KJX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

879243:PORAS RS05045
gene id: 879243:PORAS_RS05045
uniprot id: F4KKM9
names: Similarity
messages: Belongs to the Skp family.

879243:PORAS RS08380
gene id: 879243:PORAS_RS08380
uniprot id: F4KJJ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

879243:PORAS RS05170
gene id: 879243:PORAS_RS05170
uniprot id: F4KKQ6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

879243:PORAS RS02015
gene id: 879243:PORAS_RS02015
uniprot id: F4KN27
names: Similarity
messages: Belongs to the peptidase S46 family.

879243:PORAS RS05210
gene id: 879243:PORAS_RS05210
uniprot id: F4KKR4
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

879243:PORAS RS01490
gene id: 879243:PORAS_RS01490
uniprot id: F4KMD6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

879243:PORAS RS08205
gene id: 879243:PORAS_RS08205
uniprot id: F4KP50
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS07245
gene id: 879243:PORAS_RS07245
uniprot id: F4KN09
names: Similarity
messages: Belongs to the universal stress protein A family.

879243:PORAS RS07845
gene id: 879243:PORAS_RS07845
uniprot id: F4KNQ6
names: Similarity
messages: Belongs to the peptidase C15 family.

879243:PORAS RS00100
gene id: 879243:PORAS_RS00100
uniprot id: F4KKU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

879243:PORAS RS04750
gene id: 879243:PORAS_RS04750
uniprot id: F4KKG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

879243:PORAS RS07450
gene id: 879243:PORAS_RS07450
uniprot id: F4KNB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

879243:PORAS RS04445
gene id: 879243:PORAS_RS04445
uniprot id: F4KKA9
names: Similarity
messages: Belongs to the peptidase C10 family.

879243:PORAS RS03710
gene id: 879243:PORAS_RS03710
uniprot id: F4KJW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

879243:PORAS RS04980
gene id: 879243:PORAS_RS04980
uniprot id: F4KKL6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS05460
gene id: 879243:PORAS_RS05460
uniprot id: F4KL19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

879243:PORAS RS04540
gene id: 879243:PORAS_RS04540
uniprot id: F4KKC8
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS01495
gene id: 879243:PORAS_RS01495
uniprot id: F4KMD7
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

879243:PORAS RS01700
gene id: 879243:PORAS_RS01700
uniprot id: F4KMP9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

879243:PORAS RS05395
gene id: 879243:PORAS_RS05395
uniprot id: F4KL09
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

879243:PORAS RS05960
gene id: 879243:PORAS_RS05960
uniprot id: F4KLP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

879243:PORAS RS00920
gene id: 879243:PORAS_RS00920
uniprot id: F4KLN2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

879243:PORAS RS02090
gene id: 879243:PORAS_RS02090
uniprot id: F4KN43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

879243:PORAS RS03605
gene id: 879243:PORAS_RS03605
uniprot id: F4KJU9
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS01125
gene id: 879243:PORAS_RS01125
uniprot id: F4KLZ3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

879243:PORAS RS02325
gene id: 879243:PORAS_RS02325
uniprot id: F4KNF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

879243:PORAS RS06645
gene id: 879243:PORAS_RS06645
uniprot id: F4KMH0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

879243:PORAS RS04915
gene id: 879243:PORAS_RS04915
uniprot id: F4KKK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell inner membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

879243:PORAS RS05585
gene id: 879243:PORAS_RS05585
uniprot id: F4KLA9
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS03690
gene id: 879243:PORAS_RS03690
uniprot id: F4KJW4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

879243:PORAS RS05260
gene id: 879243:PORAS_RS05260
uniprot id: F4KKY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

879243:PORAS RS03740
gene id: 879243:PORAS_RS03740
uniprot id: F4KJX1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS01745
gene id: 879243:PORAS_RS01745
uniprot id: F4KMQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

879243:PORAS RS02945
gene id: 879243:PORAS_RS02945
uniprot id: F4KJB1
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

879243:PORAS RS04535
gene id: 879243:PORAS_RS04535
uniprot id: F4KKC7
names: Similarity
messages: Belongs to the glutathione peroxidase family.

879243:PORAS RS01415
gene id: 879243:PORAS_RS01415
uniprot id: F4KMC2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Fimbrium
messages: Membrane

879243:PORAS RS03825
gene id: 879243:PORAS_RS03825
uniprot id: F4KJY7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

879243:PORAS RS05535
gene id: 879243:PORAS_RS05535
uniprot id: F4KL35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

879243:PORAS RS05905
gene id: 879243:PORAS_RS05905
uniprot id: F4KLN8
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

879243:PORAS RS08265
gene id: 879243:PORAS_RS08265
uniprot id: F4KJG8
names: Similarity
messages: Belongs to the peptidase C10 family.

879243:PORAS RS05715
gene id: 879243:PORAS_RS05715
uniprot id: F4KLD7
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

879243:PORAS RS03785
gene id: 879243:PORAS_RS03785
uniprot id: F4KJX9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

879243:PORAS RS03240
gene id: 879243:PORAS_RS03240
uniprot id: F4KJN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

879243:PORAS RS07290
gene id: 879243:PORAS_RS07290
uniprot id: F4KN84
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

879243:PORAS RS06720
gene id: 879243:PORAS_RS06720
uniprot id: F4KMI6
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

879243:PORAS RS04340
gene id: 879243:PORAS_RS04340
uniprot id: F4KK87
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

879243:PORAS RS02095
gene id: 879243:PORAS_RS02095
uniprot id: F4KN44
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS01690
gene id: 879243:PORAS_RS01690
uniprot id: F4KMP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

879243:PORAS RS07205
gene id: 879243:PORAS_RS07205
uniprot id: F4KN02
names: Similarity
messages: Belongs to the peptidase C1 family.

879243:PORAS RS01735
gene id: 879243:PORAS_RS01735
uniprot id: F4KMQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

879243:PORAS RS05515
gene id: 879243:PORAS_RS05515
uniprot id: F4KL31
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

879243:PORAS RS06705
gene id: 879243:PORAS_RS06705
uniprot id: F4KMI3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

879243:PORAS RS04240
gene id: 879243:PORAS_RS04240
uniprot id: F4KK68
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

879243:PORAS RS00345
gene id: 879243:PORAS_RS00345
uniprot id: F4KL51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

879243:PORAS RS05700
gene id: 879243:PORAS_RS05700
uniprot id: F4KLD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

879243:PORAS RS00725
gene id: 879243:PORAS_RS00725
uniprot id: F4KLJ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

879243:PORAS RS03535
gene id: 879243:PORAS_RS03535
uniprot id: F4KJT4
names: Similarity
messages: Belongs to the SBNO family.

879243:PORAS RS02840
gene id: 879243:PORAS_RS02840
uniprot id: F4KNX8
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

879243:PORAS RS04210
gene id: 879243:PORAS_RS04210
uniprot id: F4KK62
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS01905
gene id: 879243:PORAS_RS01905
uniprot id: F4KMU2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

879243:PORAS RS06565
gene id: 879243:PORAS_RS06565
uniprot id: F4KM85
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

879243:PORAS RS03135
gene id: 879243:PORAS_RS03135
uniprot id: F4KJE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

879243:PORAS RS00385
gene id: 879243:PORAS_RS00385
uniprot id: F4KL59
names: Similarity
messages: Belongs to the peptidase M13 family.

879243:PORAS RS01530
gene id: 879243:PORAS_RS01530
uniprot id: F4KME7
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

879243:PORAS RS06735
gene id: 879243:PORAS_RS06735
uniprot id: F4KMI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

879243:PORAS RS00365
gene id: 879243:PORAS_RS00365
uniprot id: F4KL55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

879243:PORAS RS01625
gene id: 879243:PORAS_RS01625
uniprot id: F4KMN4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

879243:PORAS RS00075
gene id: 879243:PORAS_RS00075
uniprot id: F4KKT7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

879243:PORAS RS08490
gene id: 879243:PORAS_RS08490
uniprot id: F4KJL4
names: Similarity
messages: Belongs to the FBPase class 3 family.

879243:PORAS RS06795
gene id: 879243:PORAS_RS06795
uniprot id: F4KMK1
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

879243:PORAS RS04975
gene id: 879243:PORAS_RS04975
uniprot id: F4KKL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

879243:PORAS RS07110
gene id: 879243:PORAS_RS07110
uniprot id: F4KMY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

879243:PORAS RS02735
gene id: 879243:PORAS_RS02735
uniprot id: F4KNV3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

879243:PORAS RS07535
gene id: 879243:PORAS_RS07535
uniprot id: F4KND3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

879243:PORAS RS04630
gene id: 879243:PORAS_RS04630
uniprot id: F4KKE5
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS02855
gene id: 879243:PORAS_RS02855
uniprot id: F4KNY1
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

879243:PORAS RS02385
gene id: 879243:PORAS_RS02385
uniprot id: F4KNH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

879243:PORAS RS06665
gene id: 879243:PORAS_RS06665
uniprot id: F4KMH4
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS05720
gene id: 879243:PORAS_RS05720
uniprot id: F4KLD8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

879243:PORAS RS05385
gene id: 879243:PORAS_RS05385
uniprot id: F4KL07
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS03875
gene id: 879243:PORAS_RS03875
uniprot id: F4KJZ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

879243:PORAS RS02890
gene id: 879243:PORAS_RS02890
uniprot id: F4KNY8
names: Similarity
messages: Belongs to the peptidase C69 family.

879243:PORAS RS04465
gene id: 879243:PORAS_RS04465
uniprot id: F4KJD1
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

879243:PORAS RS04325
gene id: 879243:PORAS_RS04325
uniprot id: F4KK85
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.
messages: Belongs to the peptidase C25 family.

879243:PORAS RS05815
gene id: 879243:PORAS_RS05815
uniprot id: F4KLF7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

879243:PORAS RS00340
gene id: 879243:PORAS_RS00340
uniprot id: F4KL50
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

879243:PORAS RS02235
gene id: 879243:PORAS_RS02235
uniprot id: F4KN73
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS07140
gene id: 879243:PORAS_RS07140
uniprot id: F4KMY9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

879243:PORAS RS01925
gene id: 879243:PORAS_RS01925
uniprot id: F4KMU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

879243:PORAS RS07480
gene id: 879243:PORAS_RS07480
uniprot id: F4KNC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

879243:PORAS RS03475
gene id: 879243:PORAS_RS03475
uniprot id: F4KJS4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

879243:PORAS RS04185
gene id: 879243:PORAS_RS04185
uniprot id: F4KK57
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

879243:PORAS RS06450
gene id: 879243:PORAS_RS06450
uniprot id: F4KM63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

879243:PORAS RS06005
gene id: 879243:PORAS_RS06005
uniprot id: F4KLQ7
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

879243:PORAS RS00615
gene id: 879243:PORAS_RS00615
uniprot id: F4KLA3
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

879243:PORAS RS01795
gene id: 879243:PORAS_RS01795
uniprot id: F4KMR8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

879243:PORAS RS06285
gene id: 879243:PORAS_RS06285
uniprot id: F4KM30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

879243:PORAS RS08165
gene id: 879243:PORAS_RS08165
uniprot id: F4KP42
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

879243:PORAS RS02215
gene id: 879243:PORAS_RS02215
uniprot id: F4KN69
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

879243:PORAS RS08410
gene id: 879243:PORAS_RS08410
uniprot id: F4KJJ8
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS03220
gene id: 879243:PORAS_RS03220
uniprot id: F4KJG0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

879243:PORAS RS06060
gene id: 879243:PORAS_RS06060
uniprot id: F4KLR8
names: Similarity
messages: Belongs to the V-ATPase D subunit family.

879243:PORAS RS00935
gene id: 879243:PORAS_RS00935
uniprot id: F4KLN5
names: Similarity
messages: Belongs to the peptidase C1 family.

879243:PORAS RS06020
gene id: 879243:PORAS_RS06020
uniprot id: F4KLR0
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS00995
gene id: 879243:PORAS_RS00995
uniprot id: F4KLW6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

879243:PORAS RS02420
gene id: 879243:PORAS_RS02420
uniprot id: F4KNI0
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

879243:PORAS RS08320
gene id: 879243:PORAS_RS08320
uniprot id: F4KJI0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

879243:PORAS RS02520
gene id: 879243:PORAS_RS02520
uniprot id: F4KNJ9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

879243:PORAS RS01685
gene id: 879243:PORAS_RS01685
uniprot id: F4KMP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

879243:PORAS RS03935
gene id: 879243:PORAS_RS03935
uniprot id: F4KK07
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

879243:PORAS RS06575
gene id: 879243:PORAS_RS06575
uniprot id: F4KM87
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS02270
gene id: 879243:PORAS_RS02270
uniprot id: F4KN80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

879243:PORAS RS07370
gene id: 879243:PORAS_RS07370
uniprot id: F4KNA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

879243:PORAS RS01050
gene id: 879243:PORAS_RS01050
uniprot id: F4KLX8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS07405
gene id: 879243:PORAS_RS07405
uniprot id: F4KNA7
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS04830
gene id: 879243:PORAS_RS04830
uniprot id: F4KKI5
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

879243:PORAS RS02620
gene id: 879243:PORAS_RS02620
uniprot id: F4KNT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

879243:PORAS RS00320
gene id: 879243:PORAS_RS00320
uniprot id: F4KL46
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

879243:PORAS RS06130
gene id: 879243:PORAS_RS06130
uniprot id: F4KLT1
names: Similarity
messages: Belongs to the ComB family.

879243:PORAS RS01800
gene id: 879243:PORAS_RS01800
uniprot id: F4KMR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

879243:PORAS RS07745
gene id: 879243:PORAS_RS07745
uniprot id: F4KNN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

879243:PORAS RS08425
gene id: 879243:PORAS_RS08425
uniprot id: F4KJK1
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

879243:PORAS RS02515
gene id: 879243:PORAS_RS02515
uniprot id: F4KNJ8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS05280
gene id: 879243:PORAS_RS05280
uniprot id: F4KKZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

879243:PORAS RS02075
gene id: 879243:PORAS_RS02075
uniprot id: F4KN40
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

879243:PORAS RS01410
gene id: 879243:PORAS_RS01410
uniprot id: F4KMC1
names: Similarity
messages: Belongs to the bacteroidetes fimbrillin superfamily. FimB/Mfa2 family.

879243:PORAS RS05160
gene id: 879243:PORAS_RS05160
uniprot id: F4KKQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

879243:PORAS RS06685
gene id: 879243:PORAS_RS06685
uniprot id: F4KMH9
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

879243:PORAS RS01265
gene id: 879243:PORAS_RS01265
uniprot id: F4KM23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

879243:PORAS RS04475
gene id: 879243:PORAS_RS04475
uniprot id: F4KKB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

879243:PORAS RS01755
gene id: 879243:PORAS_RS01755
uniprot id: F4KMR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

879243:PORAS RS01920
gene id: 879243:PORAS_RS01920
uniprot id: F4KMU5
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

879243:PORAS RS03365
gene id: 879243:PORAS_RS03365
uniprot id: F4KJQ4
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS02725
gene id: 879243:PORAS_RS02725
uniprot id: F4KNV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell inner membrane
messages: Membrane

879243:PORAS RS00085
gene id: 879243:PORAS_RS00085
uniprot id: F4KKT9
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

879243:PORAS RS04510
gene id: 879243:PORAS_RS04510
uniprot id: F4KKC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

879243:PORAS RS00270
gene id: 879243:PORAS_RS00270
uniprot id: F4KKX7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

879243:PORAS RS08065
gene id: 879243:PORAS_RS08065
uniprot id: F4KP22
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

879243:PORAS RS06155
gene id: 879243:PORAS_RS06155
uniprot id: F4KLT5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS07040
gene id: 879243:PORAS_RS07040
uniprot id: F4KMW8
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

879243:PORAS RS02130
gene id: 879243:PORAS_RS02130
uniprot id: F4KN51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

879243:PORAS RS01235
gene id: 879243:PORAS_RS01235
uniprot id: F4KM16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

879243:PORAS RS02650
gene id: 879243:PORAS_RS02650
uniprot id: F4KNT8
names: Similarity
messages: Belongs to the RutC family.

879243:PORAS RS01115
gene id: 879243:PORAS_RS01115
uniprot id: F4KLZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

879243:PORAS RS01045
gene id: 879243:PORAS_RS01045
uniprot id: F4KLX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

879243:PORAS RS07035
gene id: 879243:PORAS_RS07035
uniprot id: F4KMW7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

879243:PORAS RS02475
gene id: 879243:PORAS_RS02475
uniprot id: F4KNJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

879243:PORAS RS06805
gene id: 879243:PORAS_RS06805
uniprot id: F4KMK3
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

879243:PORAS RS06555
gene id: 879243:PORAS_RS06555
uniprot id: F4KM83
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

879243:PORAS RS06760
gene id: 879243:PORAS_RS06760
uniprot id: F4KMJ4
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

879243:PORAS RS00925
gene id: 879243:PORAS_RS00925
uniprot id: F4KLN3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

879243:PORAS RS04585
gene id: 879243:PORAS_RS04585
uniprot id: F4KKD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

879243:PORAS RS00960
gene id: 879243:PORAS_RS00960
uniprot id: F4KLV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

879243:PORAS RS07795
gene id: 879243:PORAS_RS07795
uniprot id: F4KNP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

879243:PORAS RS08180
gene id: 879243:PORAS_RS08180
uniprot id: F4KP45
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS06070
gene id: 879243:PORAS_RS06070
uniprot id: F4KLS0
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

879243:PORAS RS08285
gene id: 879243:PORAS_RS08285
uniprot id: F4KJH2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

879243:PORAS RS03555
gene id: 879243:PORAS_RS03555
uniprot id: F4KJT7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

879243:PORAS RS02930
gene id: 879243:PORAS_RS02930
uniprot id: F4KJA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

879243:PORAS RS02750
gene id: 879243:PORAS_RS02750
uniprot id: F4KNV8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

879243:PORAS RS01485
gene id: 879243:PORAS_RS01485
uniprot id: F4KMD5
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS06260
gene id: 879243:PORAS_RS06260
uniprot id: F4KLV6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

879243:PORAS RS06390
gene id: 879243:PORAS_RS06390
uniprot id: F4KM51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

879243:PORAS RS05545
gene id: 879243:PORAS_RS05545
uniprot id: F4KL37
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

879243:PORAS RS03700
gene id: 879243:PORAS_RS03700
uniprot id: F4KJW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

879243:PORAS RS06065
gene id: 879243:PORAS_RS06065
uniprot id: F4KLR9
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.

879243:PORAS RS03235
gene id: 879243:PORAS_RS03235
uniprot id: F4KJG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

879243:PORAS RS03940
gene id: 879243:PORAS_RS03940
uniprot id: F4KK08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

879243:PORAS RS05040
gene id: 879243:PORAS_RS05040
uniprot id: F4KKM8
names: Similarity
messages: Belongs to the DapB family.

879243:PORAS RS02240
gene id: 879243:PORAS_RS02240
uniprot id: F4KN74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

879243:PORAS RS07120
gene id: 879243:PORAS_RS07120
uniprot id: F4KMY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

879243:PORAS RS01760
gene id: 879243:PORAS_RS01760
uniprot id: F4KMR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

879243:PORAS RS08280
gene id: 879243:PORAS_RS08280
uniprot id: F4KJH1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

879243:PORAS RS08370
gene id: 879243:PORAS_RS08370
uniprot id: F4KJJ0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

879243:PORAS RS03115
gene id: 879243:PORAS_RS03115
uniprot id: F4KJE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

879243:PORAS RS05660
gene id: 879243:PORAS_RS05660
uniprot id: F4KLC5
names: Cofactor
messages: Binds 1 zinc ion per subunit.

879243:PORAS RS02360
gene id: 879243:PORAS_RS02360
uniprot id: F4KNG7
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS05370
gene id: 879243:PORAS_RS05370
uniprot id: F4KL04
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

879243:PORAS RS00360
gene id: 879243:PORAS_RS00360
uniprot id: F4KL54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

879243:PORAS RS04855
gene id: 879243:PORAS_RS04855
uniprot id: F4KKJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

879243:PORAS RS07170
gene id: 879243:PORAS_RS07170
uniprot id: F4KMZ5
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

879243:PORAS RS05785
gene id: 879243:PORAS_RS05785
uniprot id: F4KLF1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

879243:PORAS RS05975
gene id: 879243:PORAS_RS05975
uniprot id: F4KLQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

879243:PORAS RS00835
gene id: 879243:PORAS_RS00835
uniprot id: F4KLL5
names: Similarity
messages: Belongs to the peptidase C25 family.

879243:PORAS RS01785
gene id: 879243:PORAS_RS01785
uniprot id: F4KMR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

879243:PORAS RS07130
gene id: 879243:PORAS_RS07130
uniprot id: F4KMY6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

879243:PORAS RS07320
gene id: 879243:PORAS_RS07320
uniprot id: F4KN90
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

879243:PORAS RS01105
gene id: 879243:PORAS_RS01105
uniprot id: F4KLY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

879243:PORAS RS01435
gene id: 879243:PORAS_RS01435
uniprot id: F4KMC6
names: Similarity
messages: Belongs to the serpin family.

879243:PORAS RS07975
gene id: 879243:PORAS_RS07975
uniprot id: F4KP04
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS03480
gene id: 879243:PORAS_RS03480
uniprot id: F4KJS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

879243:PORAS RS05430
gene id: 879243:PORAS_RS05430
uniprot id: F4KL16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

879243:PORAS RS04735
gene id: 879243:PORAS_RS04735
uniprot id: F4KKG6
names: Cofactor
messages: Binds 1 zinc ion per subunit.

879243:PORAS RS05765
gene id: 879243:PORAS_RS05765
uniprot id: F4KLE7
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

879243:PORAS RS08100
gene id: 879243:PORAS_RS08100
uniprot id: F4KP29
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

879243:PORAS RS02210
gene id: 879243:PORAS_RS02210
uniprot id: F4KN68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

879243:PORAS RS01220
gene id: 879243:PORAS_RS01220
uniprot id: F4KM13
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

879243:PORAS RS00900
gene id: 879243:PORAS_RS00900
uniprot id: F4KLM8
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

879243:PORAS RS05100
gene id: 879243:PORAS_RS05100
uniprot id: F4KKP2
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS06905
gene id: 879243:PORAS_RS06905
uniprot id: F4KMM1
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS02680
gene id: 879243:PORAS_RS02680
uniprot id: F4KNU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

879243:PORAS RS07485
gene id: 879243:PORAS_RS07485
uniprot id: F4KNC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

879243:PORAS RS08120
gene id: 879243:PORAS_RS08120
uniprot id: F4KP33
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS03995
gene id: 879243:PORAS_RS03995
uniprot id: F4KK21
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

879243:PORAS RS06365
gene id: 879243:PORAS_RS06365
uniprot id: F4KM46
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

879243:PORAS RS03300
gene id: 879243:PORAS_RS03300
uniprot id: F4KJP1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

879243:PORAS RS08570
gene id: 879243:PORAS_RS08570
uniprot id: F4KJU6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS03855
gene id: 879243:PORAS_RS03855
uniprot id: F4KJZ3
names: Similarity
messages: Belongs to the thioredoxin family.

879243:PORAS RS08235
gene id: 879243:PORAS_RS08235
uniprot id: F4KP55
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

879243:PORAS RS05655
gene id: 879243:PORAS_RS05655
uniprot id: F4KLC4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

879243:PORAS RS03245
gene id: 879243:PORAS_RS03245
uniprot id: F4KJN1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

879243:PORAS RS03560
gene id: 879243:PORAS_RS03560
uniprot id: F4KJT8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

879243:PORAS RS01955
gene id: 879243:PORAS_RS01955
uniprot id: F4KN15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

879243:PORAS RS03335
gene id: 879243:PORAS_RS03335
uniprot id: F4KJP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

879243:PORAS RS01720
gene id: 879243:PORAS_RS01720
uniprot id: F4KMQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

879243:PORAS RS01715
gene id: 879243:PORAS_RS01715
uniprot id: F4KMQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

879243:PORAS RS03360
gene id: 879243:PORAS_RS03360
uniprot id: F4KJQ3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

879243:PORAS RS00825
gene id: 879243:PORAS_RS00825
uniprot id: F4KLL3
names: Similarity
messages: Belongs to the SusD family.

879243:PORAS RS05780
gene id: 879243:PORAS_RS05780
uniprot id: F4KLF0
names: Similarity
messages: Belongs to the peptidase C25 family.

879243:PORAS RS05845
gene id: 879243:PORAS_RS05845
uniprot id: F4KLG3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmE subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS01890
gene id: 879243:PORAS_RS01890
uniprot id: F4KMU0
names: Similarity
messages: Belongs to the class-I fumarase family.

879243:PORAS RS01590
gene id: 879243:PORAS_RS01590
uniprot id: F4KMF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane

879243:PORAS RS01225
gene id: 879243:PORAS_RS01225
uniprot id: F4KM14
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS06545
gene id: 879243:PORAS_RS06545
uniprot id: F4KM81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

879243:PORAS RS02080
gene id: 879243:PORAS_RS02080
uniprot id: F4KN41
names: Similarity
messages: Belongs to the DEAD box helicase family.

879243:PORAS RS04890
gene id: 879243:PORAS_RS04890
uniprot id: F4KKJ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

879243:PORAS RS02830
gene id: 879243:PORAS_RS02830
uniprot id: F4KNX6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

879243:PORAS RS01770
gene id: 879243:PORAS_RS01770
uniprot id: F4KMR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

879243:PORAS RS04415
gene id: 879243:PORAS_RS04415
uniprot id: F4KKA3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS01540
gene id: 879243:PORAS_RS01540
uniprot id: F4KME9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

879243:PORAS RS00970
gene id: 879243:PORAS_RS00970
uniprot id: F4KLW1
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

879243:PORAS RS06980
gene id: 879243:PORAS_RS06980
uniprot id: F4KMV8
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

879243:PORAS RS01310
gene id: 879243:PORAS_RS01310
uniprot id: F4KMA0
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

879243:PORAS RS03330
gene id: 879243:PORAS_RS03330
uniprot id: F4KJP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

879243:PORAS RS01895
gene id: 879243:PORAS_RS01895
uniprot id: F4KMU1
names: Similarity
messages: Belongs to the class-I fumarase family.

879243:PORAS RS03585
gene id: 879243:PORAS_RS03585
uniprot id: F4KJU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

879243:PORAS RS01165
gene id: 879243:PORAS_RS01165
uniprot id: F4KM02
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

879243:PORAS RS06000
gene id: 879243:PORAS_RS06000
uniprot id: F4KLQ6
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS00820
gene id: 879243:PORAS_RS00820
uniprot id: F4KLL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

879243:PORAS RS01730
gene id: 879243:PORAS_RS01730
uniprot id: F4KMQ5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

879243:PORAS RS04410
gene id: 879243:PORAS_RS04410
uniprot id: F4KKA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

879243:PORAS RS01505
gene id: 879243:PORAS_RS01505
uniprot id: F4KME1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

879243:PORAS RS00810
gene id: 879243:PORAS_RS00810
uniprot id: F4KLL0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

879243:PORAS RS02835
gene id: 879243:PORAS_RS02835
uniprot id: F4KNX7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

879243:PORAS RS02690
gene id: 879243:PORAS_RS02690
uniprot id: F4KNU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

879243:PORAS RS01095
gene id: 879243:PORAS_RS01095
uniprot id: F4KLY7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

879243:PORAS RS01160
gene id: 879243:PORAS_RS01160
uniprot id: F4KM01
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

879243:PORAS RS03810
gene id: 879243:PORAS_RS03810
uniprot id: F4KJY4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

879243:PORAS RS05190
gene id: 879243:PORAS_RS05190
uniprot id: F4KKR0
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

879243:PORAS RS05800
gene id: 879243:PORAS_RS05800
uniprot id: F4KLF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

879243:PORAS RS00180
gene id: 879243:PORAS_RS00180
uniprot id: F4KKV9
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

879243:PORAS RS06870
gene id: 879243:PORAS_RS06870
uniprot id: F4KML5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

879243:PORAS RS02165
gene id: 879243:PORAS_RS02165
uniprot id: F4KN58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

879243:PORAS RS01070
gene id: 879243:PORAS_RS01070
uniprot id: F4KLY2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

879243:PORAS RS04985
gene id: 879243:PORAS_RS04985
uniprot id: F4KKL7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

879243:PORAS RS05630
gene id: 879243:PORAS_RS05630
uniprot id: F4KLB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

879243:PORAS RS08000
gene id: 879243:PORAS_RS08000
uniprot id: F4KP09
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

879243:PORAS RS00800
gene id: 879243:PORAS_RS00800
uniprot id: F4KLK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

879243:PORAS RS07775
gene id: 879243:PORAS_RS07775
uniprot id: F4KNP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

879243:PORAS RS02230
gene id: 879243:PORAS_RS02230
uniprot id: F4KN72
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

879243:PORAS RS06580
gene id: 879243:PORAS_RS06580
uniprot id: F4KM88
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

879243:PORAS RS04715
gene id: 879243:PORAS_RS04715
uniprot id: F4KKG2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

879243:PORAS RS02120
gene id: 879243:PORAS_RS02120
uniprot id: F4KN49
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

879243:PORAS RS06800
gene id: 879243:PORAS_RS06800
uniprot id: F4KMK2
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

879243:PORAS RS03120
gene id: 879243:PORAS_RS03120
uniprot id: F4KJE1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

879243:PORAS RS06495
gene id: 879243:PORAS_RS06495
uniprot id: F4KM72
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

879243:PORAS RS03975
gene id: 879243:PORAS_RS03975
uniprot id: F4KK17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

879243:PORAS RS00125
gene id: 879243:PORAS_RS00125
uniprot id: F4KKU8
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS05135
gene id: 879243:PORAS_RS05135
uniprot id: F4KKP9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

879243:PORAS RS06995
gene id: 879243:PORAS_RS06995
uniprot id: F4KMW0
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

879243:PORAS RS06470
gene id: 879243:PORAS_RS06470
uniprot id: F4KM67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS00955
gene id: 879243:PORAS_RS00955
uniprot id: F4KLV8
names: Similarity
messages: Belongs to the CobT family.

879243:PORAS RS01940
gene id: 879243:PORAS_RS01940
uniprot id: F4KMU9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS02630
gene id: 879243:PORAS_RS02630
uniprot id: F4KNT4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS00720
gene id: 879243:PORAS_RS00720
uniprot id: F4KLJ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

879243:PORAS RS04885
gene id: 879243:PORAS_RS04885
uniprot id: F4KKJ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

879243:PORAS RS00760
gene id: 879243:PORAS_RS00760
uniprot id: F4KLK0
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS02470
gene id: 879243:PORAS_RS02470
uniprot id: F4KNI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

879243:PORAS RS06540
gene id: 879243:PORAS_RS06540
uniprot id: F4KM80
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS07410
gene id: 879243:PORAS_RS07410
uniprot id: F4KNA8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

879243:PORAS RS06220
gene id: 879243:PORAS_RS06220
uniprot id: F4KLU8
names: Similarity
messages: Belongs to the LacAB/RpiB family.

879243:PORAS RS01620
gene id: 879243:PORAS_RS01620
uniprot id: F4KMN3
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS00395
gene id: 879243:PORAS_RS00395
uniprot id: F4KL61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

879243:PORAS RS04575
gene id: 879243:PORAS_RS04575
uniprot id: F4KKD5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

879243:PORAS RS00450
gene id: 879243:PORAS_RS00450
uniprot id: F4KL71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

879243:PORAS RS02910
gene id: 879243:PORAS_RS02910
uniprot id: F4KNZ2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

879243:PORAS RS01980
gene id: 879243:PORAS_RS01980
uniprot id: F4KN20
names: Similarity
messages: Belongs to the peptidase C25 family.

879243:PORAS RS02115
gene id: 879243:PORAS_RS02115
uniprot id: F4KN48
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS02335
gene id: 879243:PORAS_RS02335
uniprot id: F4KNG1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS08385
gene id: 879243:PORAS_RS08385
uniprot id: F4KJJ3
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS03820
gene id: 879243:PORAS_RS03820
uniprot id: F4KJY6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

879243:PORAS RS04155
gene id: 879243:PORAS_RS04155
uniprot id: F4KK53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

879243:PORAS RS03055
gene id: 879243:PORAS_RS03055
uniprot id: F4KJC7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

879243:PORAS RS00060
gene id: 879243:PORAS_RS00060
uniprot id: F4KKT4
names: Similarity
messages: Belongs to the CobH/CbiC family.

879243:PORAS RS00155
gene id: 879243:PORAS_RS00155
uniprot id: F4KKV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

879243:PORAS RS03650
gene id: 879243:PORAS_RS03650
uniprot id: F4KJV5
names: Similarity
messages: Belongs to the peptidase C25 family.

879243:PORAS RS08150
gene id: 879243:PORAS_RS08150
uniprot id: F4KP39
names: Similarity
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.

879243:PORAS RS05670
gene id: 879243:PORAS_RS05670
uniprot id: F4KLC8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS01455
gene id: 879243:PORAS_RS01455
uniprot id: F4KMD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

879243:PORAS RS07790
gene id: 879243:PORAS_RS07790
uniprot id: F4KNP5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

879243:PORAS RS01375
gene id: 879243:PORAS_RS01375
uniprot id: F4KMB4
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

879243:PORAS RS03230
gene id: 879243:PORAS_RS03230
uniprot id: F4KJG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

879243:PORAS RS00195
gene id: 879243:PORAS_RS00195
uniprot id: F4KKW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

879243:PORAS RS08555
gene id: 879243:PORAS_RS08555
uniprot id: F4KJM7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS06300
gene id: 879243:PORAS_RS06300
uniprot id: F4KM33
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

879243:PORAS RS04740
gene id: 879243:PORAS_RS04740
uniprot id: F4KKG7
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

879243:PORAS RS02395
gene id: 879243:PORAS_RS02395
uniprot id: F4KNH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

879243:PORAS RS04425
gene id: 879243:PORAS_RS04425
uniprot id: F4KKA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

879243:PORAS RS07425
gene id: 879243:PORAS_RS07425
uniprot id: F4KNB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

879243:PORAS RS07025
gene id: 879243:PORAS_RS07025
uniprot id: F4KMW5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

879243:PORAS RS07810
gene id: 879243:PORAS_RS07810
uniprot id: F4KNP9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

879243:PORAS RS01740
gene id: 879243:PORAS_RS01740
uniprot id: F4KMQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

879243:PORAS RS01705
gene id: 879243:PORAS_RS01705
uniprot id: F4KMQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

879243:PORAS RS00090
gene id: 879243:PORAS_RS00090
uniprot id: F4KKU0
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

879243:PORAS RS06430
gene id: 879243:PORAS_RS06430
uniprot id: F4KM59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

879243:PORAS RS07995
gene id: 879243:PORAS_RS07995
uniprot id: F4KP08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

879243:PORAS RS06570
gene id: 879243:PORAS_RS06570
uniprot id: F4KM86
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

879243:PORAS RS03225
gene id: 879243:PORAS_RS03225
uniprot id: F4KJG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

879243:PORAS RS02755
gene id: 879243:PORAS_RS02755
uniprot id: F4KNV9
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

879243:PORAS RS03675
gene id: 879243:PORAS_RS03675
uniprot id: F4KJW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

879243:PORAS RS07805
gene id: 879243:PORAS_RS07805
uniprot id: F4KNP8
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

879243:PORAS RS02050
gene id: 879243:PORAS_RS02050
uniprot id: F4KJD1
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

879243:PORAS RS07275
gene id: 879243:PORAS_RS07275
uniprot id: F4KN81
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

879243:PORAS RS01350
gene id: 879243:PORAS_RS01350
uniprot id: F4KMA9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

879243:PORAS RS01695
gene id: 879243:PORAS_RS01695
uniprot id: F4KMP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

879243:PORAS RS01060
gene id: 879243:PORAS_RS01060
uniprot id: F4KLY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

879243:PORAS RS05480
gene id: 879243:PORAS_RS05480
uniprot id: F4KL23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

879243:PORAS RS00220
gene id: 879243:PORAS_RS00220
uniprot id: F4KKW7
names: Similarity
messages: Belongs to the peptidase M16 family.

879243:PORAS RS01055
gene id: 879243:PORAS_RS01055
uniprot id: F4KLX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

879243:PORAS RS02555
gene id: 879243:PORAS_RS02555
uniprot id: F4KNK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylmalonyl-CoA mutase family.
messages: Catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates.
messages: Heterodimer of an alpha and a beta chain.

879243:PORAS RS05900
gene id: 879243:PORAS_RS05900
uniprot id: F4KLH4
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS05620
gene id: 879243:PORAS_RS05620
uniprot id: F4KLB6
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

879243:PORAS RS07930
gene id: 879243:PORAS_RS07930
uniprot id: F4KNZ5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

879243:PORAS RS02275
gene id: 879243:PORAS_RS02275
uniprot id: F4KNE8
names: Similarity
messages: Belongs to the peptidase C40 family.

879243:PORAS RS07350
gene id: 879243:PORAS_RS07350
uniprot id: F4KN96
names: Similarity
messages: Belongs to the peptidase C25 family.

879243:PORAS RS06140
gene id: 879243:PORAS_RS06140
uniprot id: F4KLT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

879243:PORAS RS03805
gene id: 879243:PORAS_RS03805
uniprot id: F4KJY3
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

879243:PORAS RS01195
gene id: 879243:PORAS_RS01195
uniprot id: F4KM08
names: Similarity
messages: Belongs to the GARS family.

879243:PORAS RS07440
gene id: 879243:PORAS_RS07440
uniprot id: F4KNB4
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS03205
gene id: 879243:PORAS_RS03205
uniprot id: F4KJF7
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS06050
gene id: 879243:PORAS_RS06050
uniprot id: F4KLR6
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS04680
gene id: 879243:PORAS_RS04680
uniprot id: F4KKF5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

879243:PORAS RS01305
gene id: 879243:PORAS_RS01305
uniprot id: F4KM99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

879243:PORAS RS05665
gene id: 879243:PORAS_RS05665
uniprot id: F4KLC7
names: Similarity
messages: Belongs to the Nth/MutY family.

879243:PORAS RS08210
gene id: 879243:PORAS_RS08210
uniprot id: F4KP51
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS02585
gene id: 879243:PORAS_RS02585
uniprot id: F4KNS5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS04015
gene id: 879243:PORAS_RS04015
uniprot id: F4KK25
names: Similarity
messages: Belongs to the ParB family.

879243:PORAS RS01830
gene id: 879243:PORAS_RS01830
uniprot id: F4KMS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

879243:PORAS RS01645
gene id: 879243:PORAS_RS01645
uniprot id: F4KMN8
names: Similarity
messages: Belongs to the beta-eliminating lyase family.

879243:PORAS RS05740
gene id: 879243:PORAS_RS05740
uniprot id: F4KLE2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

879243:PORAS RS04405
gene id: 879243:PORAS_RS04405
uniprot id: F4KKA1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

879243:PORAS RS00880
gene id: 879243:PORAS_RS00880
uniprot id: F4KLM4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

879243:PORAS RS04705
gene id: 879243:PORAS_RS04705
uniprot id: F4KKG0
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

879243:PORAS RS05885
gene id: 879243:PORAS_RS05885
uniprot id: F4KLH1
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

879243:PORAS RS05420
gene id: 879243:PORAS_RS05420
uniprot id: F4KL14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

879243:PORAS RS06195
gene id: 879243:PORAS_RS06195
uniprot id: F4KLU3
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

879243:PORAS RS06310
gene id: 879243:PORAS_RS06310
uniprot id: F4KM35
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

879243:PORAS RS06290
gene id: 879243:PORAS_RS06290
uniprot id: F4KM31
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

879243:PORAS RS06745
gene id: 879243:PORAS_RS06745
uniprot id: F4KMJ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

879243:PORAS RS06420
gene id: 879243:PORAS_RS06420
uniprot id: F4KM57
names: Similarity
messages: Belongs to the peptidase C69 family.

879243:PORAS RS06185
gene id: 879243:PORAS_RS06185
uniprot id: F4KLU1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

879243:PORAS RS01725
gene id: 879243:PORAS_RS01725
uniprot id: F4KMQ4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

879243:PORAS RS01775
gene id: 879243:PORAS_RS01775
uniprot id: F4KMR4
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

879243:PORAS RS08020
gene id: 879243:PORAS_RS08020
uniprot id: F4KP13
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

879243:PORAS RS03990
gene id: 879243:PORAS_RS03990
uniprot id: F4KK20
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

879243:PORAS RS00975
gene id: 879243:PORAS_RS00975
uniprot id: F4KLW2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

879243:PORAS RS01020
gene id: 879243:PORAS_RS01020
uniprot id: F4KLX1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

879243:PORAS RS03985
gene id: 879243:PORAS_RS03985
uniprot id: F4KK19
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

879243:PORAS RS06515
gene id: 879243:PORAS_RS06515
uniprot id: F4KM76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

879243:PORAS RS03665
gene id: 879243:PORAS_RS03665
uniprot id: F4KJV9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

879243:PORAS RS02955
gene id: 879243:PORAS_RS02955
uniprot id: F4KJB3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

879243:PORAS RS06255
gene id: 879243:PORAS_RS06255
uniprot id: F4KLV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XseA family.
messages: Cytoplasm

879243:PORAS RS04395
gene id: 879243:PORAS_RS04395
uniprot id: F4KK99
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

879243:PORAS RS01710
gene id: 879243:PORAS_RS01710
uniprot id: F4KMQ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

879243:PORAS RS07030
gene id: 879243:PORAS_RS07030
uniprot id: F4KMW6
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

879243:PORAS RS06295
gene id: 879243:PORAS_RS06295
uniprot id: F4KM32
names: Similarity
messages: Belongs to the PstS family.

879243:PORAS RS03370
gene id: 879243:PORAS_RS03370
uniprot id: F4KJQ5
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS03470
gene id: 879243:PORAS_RS03470
uniprot id: F4KJS3
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.

879243:PORAS RS09090
gene id: 879243:PORAS_RS09090
uniprot id: F4KKK8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

879243:PORAS RS01230
gene id: 879243:PORAS_RS01230
uniprot id: F4KM15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell inner membrane
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

879243:PORAS RS07830
gene id: 879243:PORAS_RS07830
uniprot id: F4KNQ3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

879243:PORAS RS06225
gene id: 879243:PORAS_RS06225
uniprot id: F4KLU9
names: Similarity
messages: Belongs to the pyruvoyl-dependent arginine decarboxylase family.

879243:PORAS RS03405
gene id: 879243:PORAS_RS03405
uniprot id: F4KJR1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

879243:PORAS RS07085
gene id: 879243:PORAS_RS07085
uniprot id: F4KMX7
names: Similarity
messages: Belongs to the EPSP synthase family.

879243:PORAS RS01065
gene id: 879243:PORAS_RS01065
uniprot id: F4KLY1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

879243:PORAS RS05675
gene id: 879243:PORAS_RS05675
uniprot id: F4KLC9
names: Similarity
messages: Belongs to the UPF0758 family.

879243:PORAS RS03170
gene id: 879243:PORAS_RS03170
uniprot id: F4KJF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

879243:PORAS RS04320
gene id: 879243:PORAS_RS04320
uniprot id: F4KK84
names: Similarity
messages: Belongs to the peptidase C25 family.

879243:PORAS RS04905
gene id: 879243:PORAS_RS04905
uniprot id: F4KKK0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

879243:PORAS RS03355
gene id: 879243:PORAS_RS03355
uniprot id: F4KJQ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

879243:PORAS RS05605
gene id: 879243:PORAS_RS05605
uniprot id: F4KLB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

879243:PORAS RS04030
gene id: 879243:PORAS_RS04030
uniprot id: F4KK28
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

879243:PORAS RS05070
gene id: 879243:PORAS_RS05070
uniprot id: F4KKN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

879243:PORAS RS06560
gene id: 879243:PORAS_RS06560
uniprot id: F4KM84
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

879243:PORAS RS04665
gene id: 879243:PORAS_RS04665
uniprot id: F4KKF2
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS05265
gene id: 879243:PORAS_RS05265
uniprot id: F4KKY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

879243:PORAS RS00465
gene id: 879243:PORAS_RS00465
uniprot id: F4KL74
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

879243:PORAS RS08550
gene id: 879243:PORAS_RS08550
uniprot id: F4KJM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS03815
gene id: 879243:PORAS_RS03815
uniprot id: F4KJY5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

879243:PORAS RS05560
gene id: 879243:PORAS_RS05560
uniprot id: F4KL40
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

879243:PORAS RS06620
gene id: 879243:PORAS_RS06620
uniprot id: F4KMG5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

879243:PORAS RS02450
gene id: 879243:PORAS_RS02450
uniprot id: F4KNI5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily.

879243:PORAS RS02850
gene id: 879243:PORAS_RS02850
uniprot id: F4KNY0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

879243:PORAS RS08505
gene id: 879243:PORAS_RS08505
uniprot id: F4KJL7
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS04900
gene id: 879243:PORAS_RS04900
uniprot id: F4KKJ9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-61 and Arg-64) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

879243:PORAS RS03200
gene id: 879243:PORAS_RS03200
uniprot id: F4KJF6
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS06465
gene id: 879243:PORAS_RS06465
uniprot id: F4KM66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

879243:PORAS RS02435
gene id: 879243:PORAS_RS02435
uniprot id: F4KNI2
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

879243:PORAS RS02900
gene id: 879243:PORAS_RS02900
uniprot id: F4KNZ0
names: Similarity
messages: Belongs to the asparaginase 1 family.

879243:PORAS RS01255
gene id: 879243:PORAS_RS01255
uniprot id: F4KM21
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase H family.
messages: Binds 2 metal ions per subunit. Manganese or magnesium.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

879243:PORAS RS04880
gene id: 879243:PORAS_RS04880
uniprot id: F4KKJ5
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

879243:PORAS RS05270
gene id: 879243:PORAS_RS05270
uniprot id: F4KKY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

879243:PORAS RS07415
gene id: 879243:PORAS_RS07415
uniprot id: F4KNA9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS02925
gene id: 879243:PORAS_RS02925
uniprot id: F4KJA8
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

879243:PORAS RS07325
gene id: 879243:PORAS_RS07325
uniprot id: F4KN91
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

879243:PORAS RS05580
gene id: 879243:PORAS_RS05580
uniprot id: F4KLA8
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS02035
gene id: 879243:PORAS_RS02035
uniprot id: F4KN31
names: Similarity
messages: Belongs to the peptidase C25 family.

879243:PORAS RS03050
gene id: 879243:PORAS_RS03050
uniprot id: F4KJC6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

879243:PORAS RS00140
gene id: 879243:PORAS_RS00140
uniprot id: F4KKV1
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

879243:PORAS RS04285
gene id: 879243:PORAS_RS04285
uniprot id: F4KK78
names: Similarity
messages: Belongs to the bacteroidetes fimbrillin superfamily. FimB/Mfa2 family.

879243:PORAS RS07980
gene id: 879243:PORAS_RS07980
uniprot id: F4KP05
names: Similarity
messages: Belongs to the NusB family.

879243:PORAS RS06030
gene id: 879243:PORAS_RS06030
uniprot id: F4KLR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

879243:PORAS RS07760
gene id: 879243:PORAS_RS07760
uniprot id: F4KNP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

879243:PORAS RS00200
gene id: 879243:PORAS_RS00200
uniprot id: F4KKW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

879243:PORAS RS06010
gene id: 879243:PORAS_RS06010
uniprot id: F4KLQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

879243:PORAS RS01675
gene id: 879243:PORAS_RS01675
uniprot id: F4KMP4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

879243:PORAS RS08530
gene id: 879243:PORAS_RS08530
uniprot id: F4KJM2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

879243:PORAS RS07505
gene id: 879243:PORAS_RS07505
uniprot id: F4KNC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

879243:PORAS RS06360
gene id: 879243:PORAS_RS06360
uniprot id: F4KM45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

879243:PORAS RS06675
gene id: 879243:PORAS_RS06675
uniprot id: F4KMH7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

879243:PORAS RS03565
gene id: 879243:PORAS_RS03565
uniprot id: F4KJT9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

879243:PORAS RS03460
gene id: 879243:PORAS_RS03460
uniprot id: F4KJS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

879243:PORAS RS00805
gene id: 879243:PORAS_RS00805
uniprot id: F4KLK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

879243:PORAS RS08855
gene id: 879243:PORAS_RS08855
uniprot id: F4KLB9
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

879243:PORAS RS01825
gene id: 879243:PORAS_RS01825
uniprot id: F4KMS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

879243:PORAS RS00510
gene id: 879243:PORAS_RS00510
uniprot id: F4KL83
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

879243:PORAS RS08080
gene id: 879243:PORAS_RS08080
uniprot id: F4KP25
names: Similarity
messages: Belongs to the peptidase C25 family.

879243:PORAS RS07765
gene id: 879243:PORAS_RS07765
uniprot id: F4KNP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

879243:PORAS RS06550
gene id: 879243:PORAS_RS06550
uniprot id: F4KM82
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

879243:PORAS RS01270
gene id: 879243:PORAS_RS01270
uniprot id: F4KM24
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

879243:PORAS RS01845
gene id: 879243:PORAS_RS01845
uniprot id: F4KMS9
names: Similarity
messages: Belongs to the peptidase S9C family.

879243:PORAS RS01100
gene id: 879243:PORAS_RS01100
uniprot id: F4KLY8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

879243:PORAS RS06015
gene id: 879243:PORAS_RS06015
uniprot id: F4KLQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

879243:PORAS RS03180
gene id: 879243:PORAS_RS03180
uniprot id: F4KJF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

879243:PORAS RS05550
gene id: 879243:PORAS_RS05550
uniprot id: F4KL38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

879243:PORAS RS00500
gene id: 879243:PORAS_RS00500
uniprot id: F4KL81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

879243:PORAS RS04730
gene id: 879243:PORAS_RS04730
uniprot id: F4KKG5
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

879243:PORAS RS01150
gene id: 879243:PORAS_RS01150
uniprot id: F4KLZ9
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

879243:PORAS RS07075
gene id: 879243:PORAS_RS07075
uniprot id: F4KMX5
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS04365
gene id: 879243:PORAS_RS04365
uniprot id: F4KK93
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS01445
gene id: 879243:PORAS_RS01445
uniprot id: F4KMC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

879243:PORAS RS05155
gene id: 879243:PORAS_RS05155
uniprot id: F4KKQ3
names: Cofactor
names: Similarity
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

879243:PORAS RS05570
gene id: 879243:PORAS_RS05570
uniprot id: F4KL42
names: Similarity
messages: Belongs to the peptidase S49 family.

879243:PORAS RS01805
gene id: 879243:PORAS_RS01805
uniprot id: F4KMS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

879243:PORAS RS04910
gene id: 879243:PORAS_RS04910
uniprot id: F4KKK1
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

879243:PORAS RS05000
gene id: 879243:PORAS_RS05000
uniprot id: F4KKM0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

879243:PORAS RS07300
gene id: 879243:PORAS_RS07300
uniprot id: F4KN86
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS02445
gene id: 879243:PORAS_RS02445
uniprot id: F4KNI4
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

879243:PORAS RS02330
gene id: 879243:PORAS_RS02330
uniprot id: F4KNG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

879243:PORAS RS05795
gene id: 879243:PORAS_RS05795
uniprot id: F4KLF3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS07435
gene id: 879243:PORAS_RS07435
uniprot id: F4KNB3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

879243:PORAS RS00575
gene id: 879243:PORAS_RS00575
uniprot id: F4KL95
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

879243:PORAS RS03670
gene id: 879243:PORAS_RS03670
uniprot id: F4KJW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

879243:PORAS RS07375
gene id: 879243:PORAS_RS07375
uniprot id: F4KNA1
names: Similarity
messages: Belongs to the IMPACT family.

879243:PORAS RS05530
gene id: 879243:PORAS_RS05530
uniprot id: F4KL34
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

879243:PORAS RS04860
gene id: 879243:PORAS_RS04860
uniprot id: F4KKJ1
names: Similarity
messages: Belongs to the disproportionating enzyme family.

879243:PORAS RS00520
gene id: 879243:PORAS_RS00520
uniprot id: F4KL85
names: Similarity
messages: Belongs to the SUI1 family.

879243:PORAS RS05835
gene id: 879243:PORAS_RS05835
uniprot id: F4KLG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmS subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

879243:PORAS RS06305
gene id: 879243:PORAS_RS06305
uniprot id: F4KM34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

879243:PORAS RS07430
gene id: 879243:PORAS_RS07430
uniprot id: F4KNB2
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

879243:PORAS RS04555
gene id: 879243:PORAS_RS04555
uniprot id: F4KKD1
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

879243:PORAS RS08245
gene id: 879243:PORAS_RS08245
uniprot id: F4KJG4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

879243:PORAS RS00045
gene id: 879243:PORAS_RS00045
uniprot id: F4KKT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the precorrin methyltransferase family.
messages: Homodimer.
messages: Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway.

879243:PORAS RS06710
gene id: 879243:PORAS_RS06710
uniprot id: F4KMI4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

879243:PORAS RS02845
gene id: 879243:PORAS_RS02845
uniprot id: F4KNX9
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

879243:PORAS RS00005
gene id: 879243:PORAS_RS00005
uniprot id: F4KKS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

879243:PORAS RS02350
gene id: 879243:PORAS_RS02350
uniprot id: F4KNG5
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

879243:PORAS RS02785
gene id: 879243:PORAS_RS02785
uniprot id: F4KNW7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

879243:PORAS RS00855
gene id: 879243:PORAS_RS00855
uniprot id: F4KLL9
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS06500
gene id: 879243:PORAS_RS06500
uniprot id: F4KM73
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Fimbrium
messages: Membrane

879243:PORAS RS08025
gene id: 879243:PORAS_RS08025
uniprot id: F4KP14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

879243:PORAS RS02705
gene id: 879243:PORAS_RS02705
uniprot id: F4KNU8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

879243:PORAS RS01090
gene id: 879243:PORAS_RS01090
uniprot id: F4KLY6
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

879243:PORAS RS06250
gene id: 879243:PORAS_RS06250
uniprot id: F4KLV4
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

879243:PORAS RS03070
gene id: 879243:PORAS_RS03070
uniprot id: F4KJD1
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

879243:PORAS RS01810
gene id: 879243:PORAS_RS01810
uniprot id: F4KMS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

879243:PORAS RS04515
gene id: 879243:PORAS_RS04515
uniprot id: F4KKC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

879243:PORAS RS06385
gene id: 879243:PORAS_RS06385
uniprot id: F4KM50
names: Similarity
messages: Belongs to the YicC/YloC family.

879243:PORAS RS00020
gene id: 879243:PORAS_RS00020
uniprot id: F4KKS5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

879243:PORAS RS00740
gene id: 879243:PORAS_RS00740
uniprot id: F4KLJ6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

879243:PORAS RS05680
gene id: 879243:PORAS_RS05680
uniprot id: F4KLD0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

879243:PORAS RS08260
gene id: 879243:PORAS_RS08260
uniprot id: F4KJG7
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

879243:PORAS RS00610
gene id: 879243:PORAS_RS00610
uniprot id: F4KLA2
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

879243:PORAS RS05825
gene id: 879243:PORAS_RS05825
uniprot id: F4KLF9
names: Similarity
messages: Belongs to the Skp family.

879243:PORAS RS06670
gene id: 879243:PORAS_RS06670
uniprot id: F4KMH5
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS05005
gene id: 879243:PORAS_RS05005
uniprot id: F4KKM1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

879243:PORAS RS02180
gene id: 879243:PORAS_RS02180
uniprot id: F4KN61
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

879243:PORAS RS02365
gene id: 879243:PORAS_RS02365
uniprot id: F4KNG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

879243:PORAS RS08035
gene id: 879243:PORAS_RS08035
uniprot id: F4KP16
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

879243:PORAS RS01835
gene id: 879243:PORAS_RS01835
uniprot id: F4KMS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

879243:PORAS RS02045
gene id: 879243:PORAS_RS02045
uniprot id: F4KN33
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

879243:PORAS RS05615
gene id: 879243:PORAS_RS05615
uniprot id: F4KLB5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

879243:PORAS RS04675
gene id: 879243:PORAS_RS04675
uniprot id: F4KKF4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

879243:PORAS RS00885
gene id: 879243:PORAS_RS00885
uniprot id: F4KLM5
names: Similarity
messages: Belongs to the SAICAR synthetase family.

879243:PORAS RS00550
gene id: 879243:PORAS_RS00550
uniprot id: F4KL90
names: Similarity
messages: Belongs to the UPF0102 family.

879243:PORAS RS02880
gene id: 879243:PORAS_RS02880
uniprot id: F4KNY6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

879243:PORAS RS02085
gene id: 879243:PORAS_RS02085
uniprot id: F4KN42
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

879243:PORAS RS06715
gene id: 879243:PORAS_RS06715
uniprot id: F4KMI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

879243:PORAS RS07970
gene id: 879243:PORAS_RS07970
uniprot id: F4KP03
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

879243:PORAS RS00780
gene id: 879243:PORAS_RS00780
uniprot id: F4KLK4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

879243:PORAS RS04480
gene id: 879243:PORAS_RS04480
uniprot id: F4KKB7
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

879243:PORAS RS06400
gene id: 879243:PORAS_RS06400
uniprot id: F4KM53
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS02310
gene id: 879243:PORAS_RS02310
uniprot id: F4KNF6
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS04560
gene id: 879243:PORAS_RS04560
uniprot id: F4KKD2
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

879243:PORAS RS01275
gene id: 879243:PORAS_RS01275
uniprot id: F4KM25
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

879243:PORAS RS02875
gene id: 879243:PORAS_RS02875
uniprot id: F4KNY5
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

879243:PORAS RS01930
gene id: 879243:PORAS_RS01930
uniprot id: F4KMU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

879243:PORAS RS04920
gene id: 879243:PORAS_RS04920
uniprot id: F4KKK3
names: Similarity
messages: Belongs to the aspartokinase family.

879243:PORAS RS03100
gene id: 879243:PORAS_RS03100
uniprot id: F4KJD7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS00275
gene id: 879243:PORAS_RS00275
uniprot id: F4KKX8
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

879243:PORAS RS05600
gene id: 879243:PORAS_RS05600
uniprot id: F4KLB2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

879243:PORAS RS01130
gene id: 879243:PORAS_RS01130
uniprot id: F4KLZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

879243:PORAS RS00980
gene id: 879243:PORAS_RS00980
uniprot id: F4KLW3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

879243:PORAS RS03345
gene id: 879243:PORAS_RS03345
uniprot id: F4KJQ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

879243:PORAS RS06120
gene id: 879243:PORAS_RS06120
uniprot id: F4KLS9
names: Similarity
messages: Belongs to the DprA/Smf family.

879243:PORAS RS04150
gene id: 879243:PORAS_RS04150
uniprot id: F4KK52
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

879243:PORAS RS01640
gene id: 879243:PORAS_RS01640
uniprot id: F4KMN7
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

879243:PORAS RS01975
gene id: 879243:PORAS_RS01975
uniprot id: F4KN19
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

879243:PORAS RS03395
gene id: 879243:PORAS_RS03395
uniprot id: F4KJR0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

879243:PORAS RS06700
gene id: 879243:PORAS_RS06700
uniprot id: F4KMI2
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

879243:PORAS RS01330
gene id: 879243:PORAS_RS01330
uniprot id: F4KMA5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

879243:PORAS RS04580
gene id: 879243:PORAS_RS04580
uniprot id: F4KKD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

879243:PORAS RS05770
gene id: 879243:PORAS_RS05770
uniprot id: F4KLE8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

879243:PORAS RS05865
gene id: 879243:PORAS_RS05865
uniprot id: F4KLG7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS04590
gene id: 879243:PORAS_RS04590
uniprot id: F4KKD8
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS01635
gene id: 879243:PORAS_RS01635
uniprot id: F4KMN6
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

879243:PORAS RS05465
gene id: 879243:PORAS_RS05465
uniprot id: F4KL20
names: Similarity
messages: Belongs to the CarB family.

879243:PORAS RS08350
gene id: 879243:PORAS_RS08350
uniprot id: F4KJI6
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

879243:PORAS RS05540
gene id: 879243:PORAS_RS05540
uniprot id: F4KL36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

879243:PORAS RS00645
gene id: 879243:PORAS_RS00645
uniprot id: F4KLH6
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

879243:PORAS RS05915
gene id: 879243:PORAS_RS05915
uniprot id: F4KLP0
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

879243:PORAS RS00765
gene id: 879243:PORAS_RS00765
uniprot id: F4KLK1
names: Similarity
messages: Belongs to the SufE family.

879243:PORAS RS06040
gene id: 879243:PORAS_RS06040
uniprot id: F4KLR4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

879243:PORAS RS08015
gene id: 879243:PORAS_RS08015
uniprot id: F4KP12
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

879243:PORAS RS00860
gene id: 879243:PORAS_RS00860
uniprot id: F4KLM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

879243:PORAS RS01820
gene id: 879243:PORAS_RS01820
uniprot id: F4KMS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

879243:PORAS RS00280
gene id: 879243:PORAS_RS00280
uniprot id: F4KKX9
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS03965
gene id: 879243:PORAS_RS03965
uniprot id: F4KJD1
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

879243:PORAS RS07815
gene id: 879243:PORAS_RS07815
uniprot id: F4KNQ0
names: Cofactor
messages: Binds 1 zinc ion per subunit.

879243:PORAS RS04785
gene id: 879243:PORAS_RS04785
uniprot id: F4KKH6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

879243:PORAS RS04400
gene id: 879243:PORAS_RS04400
uniprot id: F4KKA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

879243:PORAS RS08365
gene id: 879243:PORAS_RS08365
uniprot id: F4KJI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

879243:PORAS RS02305
gene id: 879243:PORAS_RS02305
uniprot id: F4KNF5
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS03590
gene id: 879243:PORAS_RS03590
uniprot id: F4KJU4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

879243:PORAS RS02865
gene id: 879243:PORAS_RS02865
uniprot id: F4KNY3
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

879243:PORAS RS06680
gene id: 879243:PORAS_RS06680
uniprot id: F4KMH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

879243:PORAS RS03465
gene id: 879243:PORAS_RS03465
uniprot id: F4KJS2
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

879243:PORAS RS06055
gene id: 879243:PORAS_RS06055
uniprot id: F4KLR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

879243:PORAS RS03925
gene id: 879243:PORAS_RS03925
uniprot id: F4KK05
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

879243:PORAS RS04375
gene id: 879243:PORAS_RS04375
uniprot id: F4KK95
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS07195
gene id: 879243:PORAS_RS07195
uniprot id: F4KN00
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

879243:PORAS RS03130
gene id: 879243:PORAS_RS03130
uniprot id: F4KJE3
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

879243:PORAS RS06510
gene id: 879243:PORAS_RS06510
uniprot id: F4KM75
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

879243:PORAS RS01765
gene id: 879243:PORAS_RS01765
uniprot id: F4KMR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

879243:PORAS RS07500
gene id: 879243:PORAS_RS07500
uniprot id: F4KNC6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

879243:PORAS RS05485
gene id: 879243:PORAS_RS05485
uniprot id: F4KL24
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879243:PORAS RS03570
gene id: 879243:PORAS_RS03570
uniprot id: F4KJU0
names: Similarity
messages: Belongs to the AIR synthase family.

879243:PORAS RS05185
gene id: 879243:PORAS_RS05185
uniprot id: F4KKQ9
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

879243:PORAS RS04135
gene id: 879243:PORAS_RS04135
uniprot id: F4KK49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

879243:PORAS RS00290
gene id: 879243:PORAS_RS00290
uniprot id: F4KKY1
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

879243:PORAS RS00815
gene id: 879243:PORAS_RS00815
uniprot id: F4KLL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

879243:PORAS RS06635
gene id: 879243:PORAS_RS06635
uniprot id: F4KMG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

879243:PORAS RS07070
gene id: 879243:PORAS_RS07070
uniprot id: F4KMX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

879243:PORAS RS01815
gene id: 879243:PORAS_RS01815
uniprot id: F4KMS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

879243:PORAS RS06380
gene id: 879243:PORAS_RS06380
uniprot id: F4KM49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

879243:PORAS RS03980
gene id: 879243:PORAS_RS03980
uniprot id: F4KK18
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

879243:PORAS RS02640
gene id: 879243:PORAS_RS02640
uniprot id: F4KNT6
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

879243:PORAS RS00400
gene id: 879243:PORAS_RS00400
uniprot id: F4KL62
names: Similarity
messages: Belongs to the peptidase S51 family.

879243:PORAS RS05930
gene id: 879243:PORAS_RS05930
uniprot id: F4KLP3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

879243:PORAS RS04835
gene id: 879243:PORAS_RS04835
uniprot id: F4KKI6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

879243:PORAS RS04875
gene id: 879243:PORAS_RS04875
uniprot id: F4KKJ4
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

879243:PORAS RS02575
gene id: 879243:PORAS_RS02575
uniprot id: F4KNL0
names: Similarity
messages: Belongs to the bacteroidetes fimbrillin superfamily. FimB/Mfa2 family.

879243:PORAS RS03350
gene id: 879243:PORAS_RS03350
uniprot id: F4KJQ1
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

879243:PORAS RS02610
gene id: 879243:PORAS_RS02610
uniprot id: F4KNT0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Belongs to the peptidase C25 family.

879243:PORAS RS08535
gene id: 879243:PORAS_RS08535
uniprot id: F4KJM3
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

879243:PORAS RS02345
gene id: 879243:PORAS_RS02345
uniprot id: F4KNG4
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS07530
gene id: 879243:PORAS_RS07530
uniprot id: F4KND2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

879243:PORAS RS05410
gene id: 879243:PORAS_RS05410
uniprot id: F4KL12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

879243:PORAS RS07955
gene id: 879243:PORAS_RS07955
uniprot id: F4KP00
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

879243:PORAS RS01320
gene id: 879243:PORAS_RS01320
uniprot id: F4KMA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

879243:PORAS RS02805
gene id: 879243:PORAS_RS02805
uniprot id: F4KNX1
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

879243:PORAS RS01470
gene id: 879243:PORAS_RS01470
uniprot id: F4KMD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

879243:PORAS RS01780
gene id: 879243:PORAS_RS01780
uniprot id: F4KMR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

879243:PORAS RS00870
gene id: 879243:PORAS_RS00870
uniprot id: F4KLM2
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS06655
gene id: 879243:PORAS_RS06655
uniprot id: F4KMH2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

879243:PORAS RS03440
gene id: 879243:PORAS_RS03440
uniprot id: F4KJR7
names: Subcellular Location Annotation
messages: Membrane

879243:PORAS RS00375
gene id: 879243:PORAS_RS00375
uniprot id: F4KL57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

879243:PORAS RS07455
gene id: 879243:PORAS_RS07455
uniprot id: F4KNB7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

879243:PORAS RS05275
gene id: 879243:PORAS_RS05275
uniprot id: F4KKZ0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

879243:PORAS RS05565
gene id: 879243:PORAS_RS05565
uniprot id: F4KL41
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

879243:PORAS RS03830
gene id: 879243:PORAS_RS03830
uniprot id: F4KJY8
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

879243:PORAS RS02545
gene id: 879243:PORAS_RS02545
uniprot id: F4KNK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane